Shear-layer structures in near-wall turbulence

NASA Technical Reports Server (NTRS)

Johansson, A. V.; Alfredsson, P. H.; Kim, J.

1987-01-01

The structure of internal shear layer observed in the near-wall region of turbulent flows is investigated by analyzing flow fields obtained from numerical simulations of channel and boundary-layer flows. It is found that the shear layer is an important contributor to the turbulence production. The conditionally averaged production at the center of the structure was almost twice as large as the long-time mean value. The shear-layer structure is also found to retain its coherence over streamwise distances on the order of a thousand viscous length units, and propagates with a constant velocity of about 10.6 u sub rho throughout the near wall region.

Quantification of wall shear stress in large blood vessels using Lagrangian interpolation functions with cine phase-contrast magnetic resonance imaging.

PubMed

Cheng, Christopher P; Parker, David; Taylor, Charles A

2002-09-01

Arterial wall shear stress is hypothesized to be an important factor in the localization of atherosclerosis. Current methods to compute wall shear stress from magnetic resonance imaging (MRI) data do not account for flow profiles characteristic of pulsatile flow in noncircular vessel lumens. We describe a method to quantify wall shear stress in large blood vessels by differentiating velocity interpolation functions defined using cine phase-contrast MRI data on a band of elements in the neighborhood of the vessel wall. Validation was performed with software phantoms and an in vitro flow phantom. At an image resolution corresponding to in vivo imaging data of the human abdominal aorta, time-averaged, spatially averaged wall shear stress for steady and pulsatile flow were determined to be within 16% and 23% of the analytic solution, respectively. These errors were reduced to 5% and 8% with doubling in image resolution. For the pulsatile software phantom, the oscillation in shear stress was predicted to within 5%. The mean absolute error of circumferentially resolved shear stress for the nonaxisymmetric phantom decreased from 28% to 15% with a doubling in image resolution. The irregularly shaped phantom and in vitro investigation demonstrated convergence of the calculated values with increased image resolution. We quantified the shear stress at the supraceliac and infrarenal regions of a human abdominal aorta to be 3.4 and 2.3 dyn/cm2, respectively.

Evaluation of Aortic Blood Flow and Wall Shear Stress in Aortic Stenosis and Its Association With Left Ventricular Remodeling.

PubMed

von Knobelsdorff-Brenkenhoff, Florian; Karunaharamoorthy, Achudhan; Trauzeddel, Ralf Felix; Barker, Alex J; Blaszczyk, Edyta; Markl, Michael; Schulz-Menger, Jeanette

2016-03-01

Aortic stenosis (AS) leads to variable stress for the left ventricle (LV) and consequently a broad range of LV remodeling. The aim of this study was to describe blood flow patterns in the ascending aorta of patients with AS and determine their association with remodeling. Thirty-seven patients with AS (14 mild, 8 moderate, 15 severe; age, 63±13 years) and 37 healthy controls (age, 60±10 years) underwent 4-dimensional-flow magnetic resonance imaging. Helical and vortical flow formations and flow eccentricity were assessed in the ascending aorta. Normalized flow displacement from the vessel center and peak systolic wall shear stress in the ascending aorta were quantified. LV remodeling was assessed based on LV mass index and the ratio of LV mass:end-diastolic volume (relative wall mass). Marked helical and vortical flow formation and eccentricity were more prevalent in patients with AS than in healthy subjects, and patients with AS exhibited an asymmetrical and elevated distribution of peak systolic wall shear stress. In AS, aortic orifice area was strongly negatively associated with vortical flow formation (P=0.0274), eccentricity (P=0.0070), and flow displacement (P=0.0021). Bicuspid aortic valve was associated with more intense helical (P=0.0098) and vortical flow formation (P=0.0536), higher flow displacement (P=0.11), and higher peak systolic wall shear stress (P=0.0926). LV mass index and relative wall mass were significantly associated with aortic orifice area (P=0.0611, P=0.0058) and flow displacement (P=0.0058, P=0.0283). In this pilot study, AS leads to abnormal blood flow pattern and peak systolic wall shear stress in the ascending aorta. In addition to aortic orifice area, normalized flow displacement was significantly associated with LV remodeling. © 2016 American Heart Association, Inc.

Navier-Stokes Computations With One-Equation Turbulence Model for Flows Along Concave Wall Surfaces

NASA Technical Reports Server (NTRS)

Wang, Chi R.

2005-01-01

This report presents the use of a time-marching three-dimensional compressible Navier-Stokes equation numerical solver with a one-equation turbulence model to simulate the flow fields developed along concave wall surfaces without and with a downstream extension flat wall surface. The 3-D Navier- Stokes numerical solver came from the NASA Glenn-HT code. The one-equation turbulence model was derived from the Spalart and Allmaras model. The computational approach was first calibrated with the computations of the velocity and Reynolds shear stress profiles of a steady flat plate boundary layer flow. The computational approach was then used to simulate developing boundary layer flows along concave wall surfaces without and with a downstream extension wall. The author investigated the computational results of surface friction factors, near surface velocity components, near wall temperatures, and a turbulent shear stress component in terms of turbulence modeling, computational mesh configurations, inlet turbulence level, and time iteration step. The computational results were compared with existing measurements of skin friction factors, velocity components, and shear stresses of the developing boundary layer flows. With a fine computational mesh and a one-equation model, the computational approach could predict accurately the skin friction factors, near surface velocity and temperature, and shear stress within the flows. The computed velocity components and shear stresses also showed the vortices effect on the velocity variations over a concave wall. The computed eddy viscosities at the near wall locations were also compared with the results from a two equation turbulence modeling technique. The inlet turbulence length scale was found to have little effect on the eddy viscosities at locations near the concave wall surface. The eddy viscosities, from the one-equation and two-equation modeling, were comparable at most stream-wise stations. The present one-equation turbulence model is an effective approach for turbulence modeling in the near solid wall surface region of flow over a concave wall.

Pulsatile flows and wall-shear stresses in models simulating normal and stenosed aortic arches

NASA Astrophysics Data System (ADS)

Huang, Rong Fung; Yang, Ten-Fang; Lan, Y.-K.

2010-03-01

Pulsatile aqueous glycerol solution flows in the models simulating normal and stenosed human aortic arches are measured by means of particle image velocimetry. Three transparent models were used: normal, 25% stenosed, and 50% stenosed aortic arches. The Womersley parameter, Dean number, and time-averaged Reynolds number are 17.31, 725, and 1,081, respectively. The Reynolds numbers based on the peak velocities of the normal, 25% stenosed, and 50% stenosed aortic arches are 2,484, 3,456, and 3,931, respectively. The study presents the temporal/spatial evolution processes of the flow pattern, velocity distribution, and wall-shear stress during the systolic and diastolic phases. It is found that the flow pattern evolving in the central plane of normal and stenosed aortic arches exhibits (1) a separation bubble around the inner arch, (2) a recirculation vortex around the outer arch wall upstream of the junction of the brachiocephalic artery, (3) an accelerated main stream around the outer arch wall near the junctions of the left carotid and the left subclavian arteries, and (4) the vortices around the entrances of the three main branches. The study identifies and discusses the reasons for the flow physics’ contribution to the formation of these features. The oscillating wall-shear stress distributions are closely related to the featured flow structures. On the outer wall of normal and slightly stenosed aortas, large wall-shear stresses appear in the regions upstream of the junction of the brachiocephalic artery as well as the corner near the junctions of the left carotid artery and the left subclavian artery. On the inner wall, the largest wall-shear stress appears in the region where the boundary layer separates.

Wall Shear Stress, Wall Pressure and Near Wall Velocity Field Relationships in a Whirling Annular Seal

NASA Technical Reports Server (NTRS)

Morrison, Gerald L.; Winslow, Robert B.; Thames, H. Davis, III

1996-01-01

The mean and phase averaged pressure and wall shear stress distributions were measured on the stator wall of a 50% eccentric annular seal which was whirling in a circular orbit at the same speed as the shaft rotation. The shear stresses were measured using flush mounted hot-film probes. Four different operating conditions were considered consisting of Reynolds numbers of 12,000 and 24,000 and Taylor numbers of 3,300 and 6,600. At each of the operating conditions the axial distribution (from Z/L = -0.2 to 1.2) of the mean pressure, shear stress magnitude, and shear stress direction on the stator wall were measured. Also measured were the phase averaged pressure and shear stress. These data were combined to calculate the force distributions along the seal length. Integration of the force distributions result in the net forces and moments generated by the pressure and shear stresses. The flow field inside the seal operating at a Reynolds number of 24,000 and a Taylor number of 6,600 has been measured using a 3-D laser Doppler anemometer system. Phase averaged wall pressure and wall shear stress are presented along with phase averaged mean velocity and turbulence kinetic energy distributions located 0.16c from the stator wall where c is the seal clearance. The relationships between the velocity, turbulence, wall pressure and wall shear stress are very complex and do not follow simple bulk flow predictions.

Near-wall similarity in a pressure-driven three-dimensional turbulent boundary layer

NASA Technical Reports Server (NTRS)

Pierce, F. J.; Mcallister, J. E.

1980-01-01

Mean velocity, measured wall pressure and wall shear stress fields were made in a three dimensional pressure-driven turbulent boundary layer created by a cylinder with trailing edge placed normal to a flat plate floor. The direct force wall shear stress measurements were made with floating element direct force sensing shear meter that responded to both the magnitude and direction of the local wall shear stress. The ability of 10 near wall similarity models to describe the near wall velocity field for the measured flow under a wide range of skewing conditions and a variety of pressure gradient and wall shear vector orientations was used.

Interaction between a normal shock wave and a turbulent boundary layer at high transonic speeds. Part 2: Wall shear stress

NASA Technical Reports Server (NTRS)

Liou, M. S.; Adamson, T. C., Jr.

1979-01-01

An analysis is presented of the flow in the two inner layers, the Reynolds stress sublayer and the wall layer. Included is the calculation of the shear stress at the wall in the interaction region. The limit processes considered are those used for an inviscid flow.

In vivo wall shear measurements within the developing zebrafish heart.

PubMed

Jamison, R Aidan; Samarage, Chaminda R; Bryson-Richardson, Robert J; Fouras, Andreas

2013-01-01

Physical forces can influence the embryonic development of many tissues. Within the cardiovascular system shear forces resulting from blood flow are known to be one of the regulatory signals that shape the developing heart. A key challenge in investigating the role of shear forces in cardiac development is the ability to obtain shear force measurements in vivo. Utilising the zebrafish model system we have developed a methodology that allows the shear force within the developing embryonic heart to be determined. Accurate wall shear measurement requires two essential pieces of information; high-resolution velocity measurements near the heart wall and the location and orientation of the heart wall itself. We have applied high-speed brightfield imaging to capture time-lapse series of blood flow within the beating heart between 3 and 6 days post-fertilization. Cardiac-phase filtering is applied to these time-lapse images to remove the heart wall and other slow moving structures leaving only the red blood cell movement. Using particle image velocimetry to calculate the velocity of red blood cells in different regions within the heart, and using the signal-to-noise ratio of the cardiac-phase filtered images to determine the boundary of blood flow, and therefore the position of the heart wall, we have been able to generate the necessary information to measure wall shear in vivo. We describe the methodology required to measure shear in vivo and the application of this technique to the developing zebrafish heart. We identify a reduction in shear at the ventricular-bulbar valve between 3 and 6 days post-fertilization and demonstrate that the shear environment of the ventricle during systole is constantly developing towards a more uniform level.

Development of a shear stress sensor to analyse the influence of polymers on the turbulent wall shear stress.

PubMed

Nottebrock, Bernardo; Grosse, Sebastian; Schröder, Wolfgang

2011-05-11

The drag reducing effect of polymers in a channel flow is well known and it is assumed that the polymer filaments interfere with the turbulent structures in the very near-wall flow. To analyse their precise effect, a micro-pillar shear stress sensor (MPS³) measurement system is developed which allows the detection of wall shear stress at high spatial and temporal resolutions. Different manufacturing techniques for the required micro-pillars are discussed and their influence on the flow is investigated evidencing the non-intrusive character of the pillars. Subsequently, a complete calibration is presented to relate the recorded deflection to wall shear stress values and to assure the correct detection over the whole expected frequency spectrum. A feasibility study about the ability to visualize the two-dimensional wall shear stress distribution completes the discussion about the validity of MPS³. In the last step, the drag reduction of a polymer filament grafted on a micro-pillar compared to a plain pillar and the application of MPS³ in an ocean-type polymer solution are investigated. The results confirm the expected behaviour found in the literature.

The effects of recirculation flows on mass transfer from the arterial wall to flowing blood.

PubMed

Zhang, Zhiguo; Deng, Xiaoyan; Fan, Yubo; Guidoin, Robert

2008-01-01

Using a sudden tubular expansion as a model of an arterial stenosis, the effect of disturbed flow on mass transfer from the arterial wall to flowing blood was studied theoretically and tested experimentally by measuring the dissolution rate of benzoic acid disks forming the outer tube of a sudden tubular expansion. The study revealed that mass transfer from vessel wall to flowing fluid in regions of disturbed flow is independent of wall shear rates. The rate of mass transfer is significantly higher in regions of disturbed flow with a local maximum around the reattachment point where the wall shear rate is zero. The experimental study also revealed that the rate of mass transfer from the vessel wall to a flowing fluid is much higher in the presence of microspheres (as models of blood cells) in the flowing fluid and under the condition of pulsatile flow than in steady flow. These results imply that flow disturbance may enhance the transport of biochemicals and macromolecules, such as plasma proteins and lipoproteins synthesized within the blood vessel wall, from the blood vessel wall to flowing blood.

Characterisation of minimal-span plane Couette turbulence with pressure gradients

NASA Astrophysics Data System (ADS)

Sekimoto, Atsushi; Atkinson, Callum; Soria, Julio

2018-04-01

The turbulence statistics and dynamics in the spanwise-minimal plane Couette flow with pressure gradients, so-called, Couette-Poiseuille (C-P) flow, are investigated using direct numerical simulation. The large-scale motion is limited in the spanwise box dimension as in the minimal-span channel turbulence of Flores & Jiménez (Phys. Fluids, vol. 22, 2010, 071704). The effect of the top wall, where normal pressure-driven Poiseuille flow is realised, is distinguished from the events on the bottom wall, where the pressure gradient results in mild or almost-zero wall-shear stress. A proper scaling of turbulence statistics in minimal-span C-P flows is presented. Also the ‘shear-less’ wall-bounded turbulence, where the Corrsin shear parameter is very weak compared to normal wall-bounded turbulence, represents local separation, which is also observed as spanwise streaks of reversed flow in full-size plane C-P turbulence. The local separation is a multi-scale event, which grows up to the order of the channel height even in the minimal-span geometry.

Effects of wall curvature on turbulence statistics

NASA Technical Reports Server (NTRS)

Moser, R. D.; Moin, P.

1985-01-01

A three-dimensional, time-dependent, direct numerical simulation of low-Reynolds number turbulent flow in a mildly curved channel was performed, and the results examined to determine the mechanism by which curvature affects wall-bounded turbulent shear flows. A spectral numerical method with about one-million modes was employed, and no explicit subgrid scale model was used. The effects of curvature on this flow were determined by comparing the concave and convex sides of the channel. The observed effects are consistent with experimental observations for mild curvature. The most significant difference in the turbulence statistics between the concave and convex sides is in the Reynolds shear stress. This is accompanied by significant differences in the terms of the Reynolds shear stress balance equations. In addition, it was found that stationary Taylor-Goertler vortices were present and that they had a significant effect on the flow by contributing to the mean Reynolds shear stress, and by enhancing the difference between the wall shear stresses.

Diagnostic Techniques to Elucidate the Aerodynamic Performance of Acoustic Liners

NASA Technical Reports Server (NTRS)

June, Jason; Bertolucci, Brandon; Ukeiley, Lawrence; Cattafesta, Louis N., III; Sheplak, Mark

2017-01-01

In support of Topic A.2.8 of NASA NRA NNH10ZEA001N, the University of Florida (UF) has investigated the use of flow field optical diagnostic and micromachined sensor-based techniques for assessing the wall shear stress on an acoustic liner. Stereoscopic particle image velocimetry (sPIV) was used to study the velocity field over a liner in the Grazing Flow Impedance Duct (GFID). The results indicate that the use of a control volume based method to determine the wall shear stress is prone to significant error. The skin friction over the liner as measured using velocity curve fitting techniques was shown to be locally reduced behind an orifice, relative to the hard wall case in a streamwise plane centered on the orifice. The capacitive wall shear stress sensor exhibited a linear response for a range of shear stresses over a hard wall. PIV over the liner is consistent with lifting of the near wall turbulent structure as it passes over an orifice, followed by a region of low wall shear stress.

Unified description of the slip phenomena in sheared polymer films: A molecular dynamics study

NASA Astrophysics Data System (ADS)

Priezjev, Nikolai

2010-03-01

The dynamic behavior of the slip length in shear flow of polymer melts past atomically smooth surfaces is investigated using MD simulations. The polymer melt was modeled as a collection of FENE-LJ bead-spring chains. We consider shear flow conditions at low pressures and weak wall-fluid interaction energy so that fluid velocity profiles are linear throughout the channel at all shear rates examined. In agreement with earlier studies we confirm that for shear- thinning fluids the slip length passes through a local minimum at low shear rates and then increases rapidly at higher shear rates. We found that the rate dependence of the slip length depends on the lattice orientation at high shear rates. The MD results show that the ratio of slip length to viscosity follows a master curve when plotted as a function of a single variable that depends on the structure factor, contact density and temperature of the first fluid layer near the solid wall. The universal dependence of the slip length holds for a number of parameters of the interface: fluid density and structure (chain length), wall-fluid interaction energy, wall density, lattice orientation, thermal or solid walls.

On the connection between Maximum Drag Reduction and Newtonian fluid flow

NASA Astrophysics Data System (ADS)

Whalley, Richard; Park, Jae-Sung; Kushwaha, Anubhav; Dennis, David; Graham, Michael; Poole, Robert

2014-11-01

To date, the most successful turbulence control technique is the dissolution of certain rheology-modifying additives in liquid flows, which results in a universal maximum drag reduction (MDR) asymptote. The MDR asymptote is a well-known phenomenon in the turbulent flow of complex fluids; yet recent direct numerical simulations of Newtonian fluid flow have identified time intervals showing key features of MDR. These intervals have been termed ``hibernating turbulence'' and are a weak turbulence state which is characterised by low wall-shear stress and weak vortical flow structures. Here, in this experimental investigation, we monitor the instantaneous wall-shear stress in a fully-developed turbulent channel flow of a Newtonian fluid with a hot-film probe whilst simultaneously measuring the streamwise velocity at various distances above the wall with laser Doppler velocimetry. We show, by conditionally sampling the streamwise velocity during low wall-shear stress events, that the MDR velocity profile is approached in an additive-free, Newtonian fluid flow. This result corroborates recent numerical investigations, which suggest that the MDR asymptote in polymer solutions is closely connected to weak, transient Newtonian flow structures.

Simulations of blood flow through a stenosed carotid artery

NASA Astrophysics Data System (ADS)

Lundin, Staffan; Meder, Samuel; Metcalfe, Ralph

2000-11-01

The human carotid artery is often the site of the formation of atherosclerotic lesions that can lead to severe reduction of blood flow to the brain, frequently resulting in a stroke. There is strong evidence that hemodynamic variables such as the wall shear stress and its spatial and temporal derivatives play a role in fostering atherosclerosis. To investigate the potential of these effects, we have performed unsteady, three-dimensional numerical simulations of blood flow through the carotid bifurcation in the presence of stenoses of varying degrees and eccentricities. The simulations indicate that regions of low maximum and minimum shear stress correlate better with lesion prone sites than low average wall shear stress. As the degree of stenosis increases, it is found that the downstream flow changes drastically for stenoses greater than about 25Downstream eddies are generated during systole that create local shear stress peaks on the internal carotid artery wall, resulting in significant reduction in flow rates through the internal carotid artery. Large secondary flows develop, and there are also periods of flow reversal during the systolic/diastolic cycle.

Mathematical modeling of power law and Herschel - Buckley non-Newtonian fluid of blood flow through a stenosed artery with permeable wall: Effects of slip velocity

NASA Astrophysics Data System (ADS)

Chitra, M.; Karthikeyan, D.

2018-04-01

A mathematical model of non-Newtonian blood flow through a stenosed artery is considered. The steadynon-Newtonian model is chosen characterized by the generalized power-law model and Herschel-Bulkley model incorporating the effect of slip velocity due to steanosed artery with permeable wall. The effects of slip velocity for non-Newtonian nature of blood on velocity, flow rate and wall shear stress of the stenosed artery with permeable wall are solved analytically. The effects of various parameters such as slip parameter (λ), power index (m) and different thickness of the stenosis (δ) on velocity, volumetric flow rate and wall shear stress are discussed through graphs.

Fluid Mechanics, Arterial Disease, and Gene Expression.

PubMed

Tarbell, John M; Shi, Zhong-Dong; Dunn, Jessilyn; Jo, Hanjoong

2014-01-01

This review places modern research developments in vascular mechanobiology in the context of hemodynamic phenomena in the cardiovascular system and the discrete localization of vascular disease. The modern origins of this field are traced, beginning in the 1960s when associations between flow characteristics, particularly blood flow-induced wall shear stress, and the localization of atherosclerotic plaques were uncovered, and continuing to fluid shear stress effects on the vascular lining endothelial) cells (ECs), including their effects on EC morphology, biochemical production, and gene expression. The earliest single-gene studies and genome-wide analyses are considered. The final section moves from the ECs lining the vessel wall to the smooth muscle cells and fibroblasts within the wall that are fluid me chanically activated by interstitial flow that imposes shear stresses on their surfaces comparable with those of flowing blood on EC surfaces. Interstitial flow stimulates biochemical production and gene expression, much like blood flow on ECs.

Nonlinear Reynolds stress model for turbulent shear flows

NASA Technical Reports Server (NTRS)

Barton, J. Michael; Rubinstein, R.; Kirtley, K. R.

1991-01-01

A nonlinear algebraic Reynolds stress model, derived using the renormalization group, is applied to equilibrium homogeneous shear flow and fully developed flow in a square duct. The model, which is quadratically nonlinear in the velocity gradients, successfully captures the large-scale inhomogeneity and anisotropy of the flows studied. The ratios of normal stresses, as well as the actual magnitudes of the stresses are correctly predicted for equilibrium homogeneous shear flow. Reynolds normal stress anisotropy and attendant turbulence driven secondary flow are predicted for a square duct. Profiles of mean velocity and normal stresses are in good agreement with measurements. Very close to walls, agreement with measurements diminishes. The model has the benefit of containing no arbitrary constants; all values are determined directly from the theory. It seems that near wall behavior is influenced by more than the large scale anisotropy accommodated in the current model. More accurate near wall calculations may well require a model for anisotropic dissipation.

Anisotropic shear stress patterns predict the orientation of convergent tissue movements in the embryonic heart

PubMed Central

2017-01-01

Myocardial contractility and blood flow provide essential mechanical cues for the morphogenesis of the heart. In general, endothelial cells change their migratory behavior in response to shear stress patterns, according to flow directionality. Here, we assessed the impact of shear stress patterns and flow directionality on the behavior of endocardial cells, the specialized endothelial cells of the heart. At the early stages of zebrafish heart valve formation, we show that endocardial cells are converging to the valve-forming area and that this behavior depends upon mechanical forces. Quantitative live imaging and mathematical modeling allow us to correlate this tissue convergence with the underlying flow forces. We predict that tissue convergence is associated with the direction of the mean wall shear stress and of the gradient of harmonic phase-averaged shear stresses, which surprisingly do not match the overall direction of the flow. This contrasts with the usual role of flow directionality in vascular development and suggests that the full spatial and temporal complexity of the wall shear stress should be taken into account when studying endothelial cell responses to flow in vivo. PMID:29183943

Hydraulic properties of 3D rough-walled fractures during shearing: An experimental study

NASA Astrophysics Data System (ADS)

Yin, Qian; Ma, Guowei; Jing, Hongwen; Wang, Huidong; Su, Haijian; Wang, Yingchao; Liu, Richeng

2017-12-01

This study experimentally analyzed the influence of shear processes on nonlinear flow behavior through 3D rough-walled rock fractures. A high-precision apparatus was developed to perform stress-dependent fluid flow tests of fractured rocks. Then, water flow tests on rough-walled fractures with different mechanical displacements were conducted. At each shear level, the hydraulic pressure ranged from 0 to 0.6 MPa, and the normal load varied from 7 to 35 kN. The results show that (i) the relationship between the volumetric flow rate and hydraulic gradient of rough-walled fractures can be well fit using Forchheimer's law. Notably, both the linear and nonlinear coefficients in Forchheimer's law decrease during shearing; (ii) a sixth-order polynomial function is used to evaluate the transmissivity based on the Reynolds number of fractures during shearing. The transmissivity exhibits a decreasing trend as the Reynolds number increases and an increasing trend as the shear displacement increases; (iii) the critical hydraulic gradient, critical Reynolds number and equivalent hydraulic aperture of the rock fractures all increase as the shear displacement increases. When the shear displacement varies from 0 to 15 mm, the critical hydraulic gradient ranges from 0.3 to 2.2 for a normal load of 7 kN and increases to 1.8-8.6 for a normal load of 35 kN; and (iv) the Forchheimer law results are evaluated by plotting the normalized transmissivity of the fractures during shearing against the Reynolds number. An increase in the normal load shifts the fitted curves downward. Additionally, the Forchheimer coefficient β decreases with the shear displacement but increases with the applied normal load.

Shear stress and flow dynamics of the femoral vein among obese patients who qualify for bariatric surgery.

PubMed

Wiewiora, Maciej; Piecuch, Jerzy; Glűck, Marek; Slowinska-Lozynska, Ludmila; Sosada, Krystyn

2013-01-01

The aim of this study was to evaluate the effects of obesity on wall shear stress and its relationship to erythrocyte aggregation. We studied 35 morbidly obese patients who were qualified for bariatric surgery. The control group consisted of 20 non-obese people. Blood rheological measurements were performed using the Laser-assisted Optical Rotational Cell Analyzer (Mechatronics, the Netherlands) and a cone-plate viscometer (Brookfield DV-II). The venous flow dynamics were assessed using a duplex ultrasound. The shear rate was estimated from the measured blood flow velocity and the diameter of the femoral vein. Venous wall shear stress was calculated from the whole blood viscosity and the shear rate. The shear rate (P < 0.005) and the venous wall shear stress (P < 0.05) were significantly lower in obese patients compared with the controls. The aggregation index (P < 0.001), syllectogram amplitude - AMP (P < 0.05) and Tslow (P < 0.001) were significantly higher in the obese patients; the aggregation half-time (P < 0.001) and Tfast (P < 0.001) were decreased compared with the control group. Multivariate regression analyses found waist circumference (β -0.31, P < 0.05), thigh circumference (β 0.33, P < 0.05) and Tslow (β -0.47, P < 0.005) to be variables that independently influenced the shear rate. Nevertheless, the AMP (β 0.34, P < 0.05) and Tslow (β -0.47, P < 0.01) were independent predictors that influenced the wall shear stress. This study indicates that there is a relationship between wall shear stress in the femoral vein and the rheological impairment of the RBC among obese patients, but further studies are necessary to confirm this suggestion.

Flow and wall shear stress characterization after endovascular aneurysm repair and endovascular aneurysm sealing in an infrarenal aneurysm model.

PubMed

Boersen, Johannes T; Groot Jebbink, Erik; Versluis, Michel; Slump, Cornelis H; Ku, David N; de Vries, Jean-Paul P M; Reijnen, Michel M P J

2017-12-01

Endovascular aneurysm repair (EVAR) with a modular endograft has become the preferred treatment for abdominal aortic aneurysms. A novel concept is endovascular aneurysm sealing (EVAS), consisting of dual endoframes surrounded by polymer-filled endobags. This dual-lumen configuration is different from a bifurcation with a tapered trajectory of the flow lumen into the two limbs and may induce unfavorable flow conditions. These include low and oscillatory wall shear stress (WSS), linked to atherosclerosis, and high shear rates that may result in thrombosis. An in vitro study was performed to assess the impact of EVAR and EVAS on flow patterns and WSS. Four abdominal aortic aneurysm phantoms were constructed, including three stented models, to study the influence of the flow divider on flow (Endurant [Medtronic, Minneapolis, Minn], AFX [Endologix, Irvine, Calif], and Nellix [Endologix]). Experimental models were tested under physiologic resting conditions, and flow was visualized with laser particle imaging velocimetry, quantified by shear rate, WSS, and oscillatory shear index (OSI) in the suprarenal aorta, renal artery (RA), and common iliac artery. WSS and OSI were comparable for all models in the suprarenal aorta. The RA flow profile in the EVAR models was comparable to the control, but a region of lower WSS was observed on the caudal wall compared with the control. The EVAS model showed a stronger jet flow with a higher shear rate in some regions compared with the other models. Small regions of low WSS and high OSI were found near the distal end of all stents in the common iliac artery compared with the control. Maximum shear rates in each region of interest were well below the pathologic threshold for acute thrombosis. The different stent designs do not influence suprarenal flow. Lower WSS is observed in the caudal wall of the RA after EVAR and a higher shear rate after EVAS. All stented models have a small region of low WSS and high OSI near the distal outflow of the stents. Copyright © 2016 Society for Vascular Surgery. Published by Elsevier Inc. All rights reserved.

Stent implantation influence wall shear stress evolution

NASA Astrophysics Data System (ADS)

Bernad, S. I.; Totorean, A. F.; Bosioc, A. I.; Petre, I.; Bernad, E. S.

2016-06-01

Local hemodynamic factors are known affect the natural history of the restenosis critically after coronary stenting of atherosclerosis. Stent-induced flows disturbance magnitude dependent directly on the strut design. The impact of flow alterations around struts vary as the strut geometrical parameters change. Our results provide data regarding the hemodynamic parameters for the blood flow in both stenosed and stented coronary artery under physiological conditions, namely wall shear stress and pressure drop.

Shear localization and effective wall friction in a wall bounded granular flow

NASA Astrophysics Data System (ADS)

Artoni, Riccardo; Richard, Patrick

2017-06-01

In this work, granular flow rheology is investigated by means of discrete numerical simulations of a torsional, cylindrical shear cell. Firstly, we focus on azimuthal velocity profiles and study the effect of (i) the confining pressure, (ii) the particle-wall friction coefficient, (iii) the rotating velocity of the bottom wall and (iv) the cell diameter. For small cell diameters, azimuthal velocity profiles are nearly auto-similar, i.e. they are almost linear with the radial coordinate. Different strain localization regimes are observed : shear can be localized at the bottom, at the top of the shear cell, or it can be even quite distributed. This behavior originates from the competition between dissipation at the sidewalls and dissipation in the bulk of the system. Then we study the effective friction at the cylindrical wall, and point out the strong link between wall friction, slip and fluctuations of forces and velocities. Even if the system is globally below the sliding threshold, force fluctuations trigger slip events, leading to a nonzero wall slip velocity and an effective wall friction coefficient different from the particle-wall one. A scaling law was found linking slip velocity, granular temperature in the main flow direction and effective friction. Our results suggest that fluctuations are an important ingredient for theories aiming to capture the interface rheology of granular materials.

Wall shear stress measurement in blade end-wall corner region

NASA Technical Reports Server (NTRS)

Bhargava, R.; Raj, R.; Boldman, D. R.

1987-01-01

The magnitude and the direction of wall shear stress and surface pressure in the blade end-wall corner region were investigated. The measurements were obtained on a specially designed Preston tube, the tip of which could be concentrically rotated about its axis of rotation at the measurement location. The magnitude of wall shear stress in the vicinity of the corner was observed to increase significantly (170 percent) compared to its far-upstream value; the increase was consistently higher on the blade surface compared to the value on the plate surface of the blade end-wall corner. On both surfaces in the blade end-wall corner, the variation of the wall shear stress direction was found to be more predominant in the vicinity of the blade leading-edge location. The trend of the measured wall shear stress direction showed good agreement with the limiting streamline directions obtained from the flow visualization studies.

Analysis of flow disturbance in a stenosed carotid artery bifurcation using two-equation transitional and turbulence models.

PubMed

Tan, F P P; Soloperto, G; Bashford, S; Wood, N B; Thom, S; Hughes, A; Xu, X Y

2008-12-01

In this study, newly developed two-equation turbulence models and transitional variants are employed for the prediction of blood flow patterns in a diseased carotid artery where the growth, progression, and structure of the plaque at rupture are closely linked to low and oscillating wall shear stresses. Moreover, the laminar-turbulent transition in the poststenotic zone can alter the separation zone length, wall shear stress, and pressure distribution over the plaque, with potential implications for stresses within the plaque. Following the validation with well established experimental measurements and numerical studies, a magnetic-resonance (MR) image-based model of the carotid bifurcation with 70% stenosis was reconstructed and simulated using realistic patient-specific conditions. Laminar flow, a correlation-based transitional version of Menter's hybrid k-epsilon/k-omega shear stress transport (SST) model and its "scale adaptive simulation" (SAS) variant were implemented in pulsatile simulations from which analyses of velocity profiles, wall shear stress, and turbulence intensity were conducted. In general, the transitional version of SST and its SAS variant are shown to give a better overall agreement than their standard counterparts with experimental data for pulsatile flow in an axisymmetric stenosed tube. For the patient-specific case reported, the wall shear stress analysis showed discernable differences between the laminar flow and SST transitional models but virtually no difference between the SST transitional model and its SAS variant.

An experimental study of near wall flow parameters in the blade end-wall corner region

NASA Technical Reports Server (NTRS)

Bhargava, Rakesh K.; Raj, Rishi S.

1989-01-01

The near wall flow parameters in the blade end-wall corner region is investigated. The blade end-wall corner region was simulated by mounting an airfoil section (NACA 65-015 base profile) symmetric blades on both sides of the flat plate with semi-circular leading edge. The initial 7 cm from the leading edge of the flat plate was roughened by gluing No. 4 floor sanding paper to artificially increase the boundary layer thickness on the flat plate. The initial flow conditions of the boundary layer upstream of the corner region are expected to dictate the behavior of flow inside the corner region. Therefore, an experimental investigation was extended to study the combined effect of initial roughness and increased level of free stream turbulence on the development of a 2-D turbulent boundary layer in the absence of the blade. The measurement techniques employed in the present investigation included, the conventional pitot and pitot-static probes, wall taps, the Preston tube, piezoresistive transducer and the normal sensor hot-wire probe. The pitot and pitot-static probes were used to obtain mean velocity profile measurements within the boundary layer. The measurements of mean surface static pressure were obtained with the surface static tube and the conventional wall tap method. The wall shear vector measurements were made with a specially constructed Preston tube. The flush mounted piezoresistive type pressure transducer were employed to measure the wall pressure fluctuation field. The velocity fluctuation measurements, used in obtaining the wall pressure-velocity correlation data, were made with normal single sensor hot-wire probe. At different streamwise stations, in the blade end-wall corner region, the mean values of surface static pressure varied more on the end-wall surface in the corner region were mainly caused by the changes in the curvature of the streamlines. The magnitude of the wall shear stress in the blade end-wall corner region increased significantly in the close vicinity of the corner line. The maximum value of the wall shear stress and its location from the corner line, on both the surfaces forming the corner region, were observed to change along the corner. These observed changes in the maximum values of the wall shear stress and its location from the corner line could be associated with the stretching and attenuation of the horseshoe vortex. The wall shear stress vectors in the blade end-wall corner region were observed to be more skewed on the end-wall surface as compared to that on the blade surface. The differences in the wall shear stress directions obtained with the Preston tube and flow visualization method were within the range in which the Preston tube was found to be insensitive to the yaw angle.

Magnetic resonance imaging 4-D flow-based analysis of aortic hemodynamics in Turner syndrome.

PubMed

Arnold, Raoul; Neu, Marie; Hirtler, Daniel; Gimpel, Charlotte; Markl, Michael; Geiger, Julia

2017-04-01

Cardiovascular surveillance is important in Turner syndrome because of the increased risk of aortic dilation and dissection with consecutively increased mortality. To compare 4-D flow MRI for the characterization of aortic 3-D flow patterns, dimensions and vessel wall parameters in pediatric patients with Turner syndrome and age-matched controls. We performed 4-D flow MRI measuring in vivo 3-D blood flow with coverage of the thoracic aorta in 25 patients with Turner syndrome and in 16 female healthy controls (age mean ± standard deviation were 16 ± 5 years and 17 ± 4 years, respectively). Blood flow was visualized by time-resolved 3-D path lines. Visual grading of aortic flow in terms of helices and vortices was performed by two independent observers. Quantitative analysis included measurement of aortic diameters, quantification of peak systolic wall shear stress, pulsatility index and oscillatory shear index at eight defined sites. Patients with Turner syndrome had significantly larger aortic diameters normalized to BSA, increased vortices in the ascending aorta and elevated helix flow in the ascending and descending aorta compared to controls (all P<0.03). Patients with abnormal helical or vortical flow in the ascending aorta had significantly larger diameters of the ascending aorta (P<0.03). Peak systolic wall shear stress, pulsatility index and oscillatory shear index were significantly lower in Turner patients compared to controls (p=0.02, p=0.002 and p=0.01 respectively). Four-dimensional flow MRI provides new insights into the altered aortic hemodynamics and wall shear stress that could have an impact on the development of aortic dissections.

Turbulence significantly increases pressure and fluid shear stress in an aortic aneurysm model under resting and exercise flow conditions.

PubMed

Khanafer, Khalil M; Bull, Joseph L; Upchurch, Gilbert R; Berguer, Ramon

2007-01-01

The numerical models of abdominal aortic aneurysm (AAA) in use do not take into account the non-Newtonian behavior of blood and the development of local turbulence. This study examines the influence of pulsatile, turbulent, non-Newtonian flow on fluid shear stresses and pressure changes under rest and exercise conditions. We numerically analyzed pulsatile turbulent flow, using simulated physiological rest and exercise waveforms, in axisymmetric-rigid aortic aneurysm models (AAMs). Discretization of governing equations was achieved using a finite element scheme. Maximum turbulence-induced shear stress was found at the distal end of an AAM. In large AAMs (dilated to undilated diameter ratio = 3.33) at peak systolic flow velocity, fluid shear stress during exercise is 70.4% higher than at rest. Our study provides a numerical, noninvasive method for obtaining detailed data on the forces generated by pulsatile turbulent flow in AAAs that are difficult to study in humans and in physical models. Our data suggest that increased flow turbulence results in increased shear stress in aneurysms. While pressure readings are fairly uniform along the length of an aneurysm, the kinetic energy generated by turbulence impacting on the wall of the distal half of the aneurysm increases fluid and wall shear stress at this site. If the increased fluid shear stress results in further dilation and hence further turbulence, wall stress may be a mechanism for aneurysmal growth and eventual rupture.

Gas Near a Wall: Shortened Mean Free Path, Reduced Viscosity, and the Manifestation of the Knudsen Layer in the Navier-Stokes Solution of a Shear Flow

NASA Astrophysics Data System (ADS)

Abramov, Rafail V.

2018-06-01

For the gas near a solid planar wall, we propose a scaling formula for the mean free path of a molecule as a function of the distance from the wall, under the assumption of a uniform distribution of the incident directions of the molecular free flight. We subsequently impose the same scaling onto the viscosity of the gas near the wall and compute the Navier-Stokes solution of the velocity of a shear flow parallel to the wall. Under the simplifying assumption of constant temperature of the gas, the velocity profile becomes an explicit nonlinear function of the distance from the wall and exhibits a Knudsen boundary layer near the wall. To verify the validity of the obtained formula, we perform the Direct Simulation Monte Carlo computations for the shear flow of argon and nitrogen at normal density and temperature. We find excellent agreement between our velocity approximation and the computed DSMC velocity profiles both within the Knudsen boundary layer and away from it.

The dynamics and control of fluctuating pressure loads in the reattachment region of a supersonic free shear layer

NASA Technical Reports Server (NTRS)

Smits, A. J.

1990-01-01

The primary aim is to investigate the mechanisms which cause the unsteady wall-pressure fluctuations in shock wave turbulent shear layer interactions. The secondary aim is to find means to reduce the magnitude of the fluctuating pressure loads by controlling the unsteady shock motion. The particular flow proposed for study is the unsteady shock wave interaction formed in the reattachment zone of a separated supersonic flow. Similar flows are encountered in many practical situations, and they are associated with high levels of fluctuating wall pressure. Wall pressure fluctuations were measured in the reattachment region of the supersonic free shear layer. The free shear layer was formed by the separation of a Mach 2.9 turbulent boundary layer from a backward facing step. Reattachment occurred on a 20 deg ramp. By adjusting the position of the ramp, the base pressure was set equal to the freestream pressure, and the free shear layer formed in the absence of a separation shock. An array of flush-mounted, miniature, high-frequency pressure transducers was used to make multichannel measurements of the fluctuating wall pressure in the vicinity of the reattachment region. Contrary to previous observations of this flow, the reattachment region was found to be highly unsteady, and the pressure fluctuations were found to be significant. The overall behavior of the wall pressure loading is similar in scale and magnitude to the unsteadiness of the wall pressure field in compression ramp flows at the same Mach number. Rayleigh scattering was used to visualize the instantaneous shock structure in the streamwise and spanwise direction. Spanwise wrinkles on the order of half the boundary layer thickness were observed.

Direct and Large Eddy Simulation of non-equilibrium wall-bounded turbulent flows

NASA Astrophysics Data System (ADS)

Park, Hee-Jun

2005-11-01

The performance of several existing SGS models in non-equilibrium wall-bounded turbulent flows is investigated through comparisons of LES and DNS. The test problem is a shear-driven three-dimensional turbulent channel flow at base Reτ˜210 established by impulsive motion of one of the channel walls in the spanwise direction with a spanwise velocity equal to 3/4 of the bulk mean velocity in the channel. The DNS and LES are performed using pseudo-spectral methods with resolutions of 128x128x129 and 32x64x65, respectively. The SGS models tested include the nonlinear Interactions Approximation model (NIA) [Haliloglu and Akhavan (2004)], the Dynamic Smagorinsky model (DSM) [Germano et al. (1991)], and the Dynamic Mixed Model (DMM) [Zang et al. (1993)]. The results show that NIA gives the best overall agreement with DNS. Both DMM and DSM over-predict the decay of the mean streamwise wall shear stress on the moving wall, while NIA gives results in close agreements with DNS. Similarly, NIA gives the best agreement with DNS in the prediction of the mean velocity, the higher-order turbulence statistics, and the lag angle between the mean shear and the turbulent shear stress. These results suggest that non-equilibrium wall-bounded turbulent flows can be accurately computed by LES with NIA as the SGS model.

The Thin Oil Film Equation

NASA Technical Reports Server (NTRS)

Brown, James L.; Naughton, Jonathan W.

1999-01-01

A thin film of oil on a surface responds primarily to the wall shear stress generated on that surface by a three-dimensional flow. The oil film is also subject to wall pressure gradients, surface tension effects and gravity. The partial differential equation governing the oil film flow is shown to be related to Burgers' equation. Analytical and numerical methods for solving the thin oil film equation are presented. A direct numerical solver is developed where the wall shear stress variation on the surface is known and which solves for the oil film thickness spatial and time variation on the surface. An inverse numerical solver is also developed where the oil film thickness spatial variation over the surface at two discrete times is known and which solves for the wall shear stress variation over the test surface. A One-Time-Level inverse solver is also demonstrated. The inverse numerical solver provides a mathematically rigorous basis for an improved form of a wall shear stress instrument suitable for application to complex three-dimensional flows. To demonstrate the complexity of flows for which these oil film methods are now suitable, extensive examination is accomplished for these analytical and numerical methods as applied to a thin oil film in the vicinity of a three-dimensional saddle of separation.

Evolution and dynamics of shear-layer structures in near-wall turbulence

NASA Technical Reports Server (NTRS)

Johansson, Arne V.; Alfredsson, P. H.; Kim, John

1991-01-01

Near-wall flow structures in turbulent shear flows are analyzed, with particular emphasis on the study of their space-time evolution and connection to turbulence production. The results are obtained from investigation of a database generated from direct numerical simulation of turbulent channel flow at a Reynolds number of 180 based on half-channel width and friction velocity. New light is shed on problems associated with conditional sampling techniques, together with methods to improve these techniques, for use both in physical and numerical experiments. The results clearly indicate that earlier conceptual models of the processes associated with near-wall turbulence production, based on flow visualization and probe measurements need to be modified. For instance, the development of asymmetry in the spanwise direction seems to be an important element in the evolution of near-wall structures in general, and for shear layers in particular. The inhibition of spanwise motion of the near-wall streaky pattern may be the primary reason for the ability of small longitudinal riblets to reduce turbulent skin friction below the value for a flat surface.

A three-dimensional turbulent separated flow and related mesurements

NASA Technical Reports Server (NTRS)

Pierce, F. J.

1985-01-01

The applicability of and the limits on the applicability of 11 near wall similarity laws characterizing three-dimensional turbulent boundary layer flows were determined. A direct force sensing local wall shear stress meter was used in both pressure-driven and shear-driven three-dimensional turbulent boundary layers, together with extensive mean velocity field and wall pressure field data. This resulted in a relatively large number of graphical comparisons of the predictive ability of 10 of these 11 similarity models relative to measured data over a wide range of flow conditions. Documentation of a complex, separated three-dimensional turbulent flow as a standard test case for evaluating the predictive ability of numerical codes solving such flows is presented.

Pulsatile extracorporeal circulation during on-pump cardiac surgery enhances aortic wall shear stress.

PubMed

Assmann, Alexander; Benim, Ali Cemal; Gül, Fethi; Lux, Philipp; Akhyari, Payam; Boeken, Udo; Joos, Franz; Feindt, Peter; Lichtenberg, Artur

2012-01-03

Controversy on superiority of pulsatile versus non-pulsatile extracorporeal circulation in cardiac surgery still continues. Stroke as one of the major adverse events during cardiopulmonary bypass is, in the majority of cases, caused by mobilization of aortic arteriosclerotic plaques that is inducible by pathologically elevated wall shear stress values. The present study employs computational fluid dynamics to evaluate the aortic blood flow and wall shear stress profiles under the influence of antegrade or retrograde perfusion with pulsatile versus non-pulsatile extracorporeal circulation. While, compared to physiological flow, a non-pulsatile perfusion resulted in generally decreased blood velocities and only moderately increased shear forces (48 Pa versus 20 Pa antegradely and 127 Pa versus 30 Pa retrogradely), a pulsatile perfusion extensively enhanced the occurrence of turbulences, maximum blood flow speed and maximum wall shear stress (1020 Pa versus 20 Pa antegradely and 1178 Pa versus 30 Pa retrogradely). Under these circumstances arteriosclerotic embolism has to be considered. Further simulations and experimental work are necessary to elucidate the impact of our findings on the scientific discourse of pulsatile versus non-pulsatile extracorporeal circulation. Copyright © 2011 Elsevier Ltd. All rights reserved.

Evolution of hairpin vortices in a shear flow

NASA Technical Reports Server (NTRS)

Hon, T.-L.; Walker, J. D. A.

1988-01-01

Recent experimental studies suggest that the hairpin vortex plays an important (and perhaps dominant) role in the dynamics of turbulent flows near walls. In this study a numerical procedure is developed to allow the accurate computation of the trajectory of a 3-D vortex having a small core radius. For hairpin vortices which are convected in a shear flow above a wall, the calculated results show that a 2-D vortex containing a small 3-D disturbance distorts into a complex shape with subsidiary hairpin vortices forming outboard of the original hairpin vortex. As the vortex moves above the wall, it induces unsteady motion in the viscous flow near the wall: numerical solutions suggest that the boundary-layer flow near the wall will ultimately erupt in response to the motion of the hairpin vortex and in the process a secondary hairpin vortex will be created. The computer results agree with recent experimental investigations.

Dynamics of model blood cells in shear flow

NASA Astrophysics Data System (ADS)

Podgorski, Thomas; Callens, Natacha; Minetti, Christophe; Coupier, Gwennou; Dubois, Frank; Misbah, Chaouqi

The dynamics of a vesicle suspension in shear flow was investigated by digital holographic microscopy [1] in parabolic flights and in the MASER 11 sounding rocket. Vesicles are lipid membranes which mimic the mechanical behaviour of cells, such as red blood cells in flow. In a simple shear flow between parallel walls, a lift force of purely viscous origin pushes vesicles away from walls. Our parabolic flight experiments [2] reveal that the lift velocity in a dilute suspen-sion is well described by theoretical predictions by Olla. As vesicles gather near the center of the flow chamber due to lift forces from both walls, one expects hydrodynamic interactions of pairs of vesicles to result in shear induced diffusion in the suspension. The BIOMICS experi-ment in the MASER 11 sounding rocket revealed a complex spatial structure of a polydisperse vesicle suspension due to the interplay between lift forces from the walls and hydrodynamic interactions. These phenomena have a strong impact on the structure and rheology of blood in small vessels, and a precise knowledge of the dynamics of migration and diffusion of soft particles in flow can lead to alternative ways to separate and sort blood cells. 1. Dubois, F., Schockaert, C., Callens, N., Yourrassowsky, C., "Focus plane detection criteria in digital holography microscopy by amplitude analysis", Opt. Express, Vol. 14, pp 5895-5908, 2006 2. Callens, N., Minetti, C., Coupier, G., Mader, M.-A., Dubois, F., Misbah, C., Podgorski, T., "Hydrodynamics lift of vesicles under shear flow in microgravity", Europhys. Lett., Vol. 83, p. 24002, 2008

Development of a wall-shear-stress sensor and measurements in mini-channels with partial blockages

NASA Astrophysics Data System (ADS)

Afara, Samer; Medvescek, James; Mydlarski, Laurent; Baliga, Bantwal R.; MacDonald, Mark

2014-05-01

The design, construction, operation and validation of a wall-shear-stress sensor, and measurements obtained using this sensor in air flows downstream of partial blockages in a mini-channel are presented. The sensor consisted of a hot wire mounted over a small rectangular slot and operated using a constant-temperature anemometer. It was used to investigate flows similar to those within the mini-channels inside notebook computers. The overall goal of the present work was to develop a sensor suitable for measurements of the wall-shear stress in such flows, which can be used to validate corresponding numerical simulations, as the latter are known to be often surprisingly inaccurate. To this end, measurements of the wall-shear stress, and the corresponding statistical moments and power spectral densities, were obtained at different distances downstream of the partial blockage, with blockage ratios of 39.7, 59.2, and 76.3 %. The Reynolds number (based on average velocity and hydraulic diameter) ranged from 100 to 900. The results confirmed the presence of unsteadiness, separation, reattachment, and laminar-turbulent transition in the ostensibly laminar flow of air in mini-channels with partial blockages. The present results demonstrate why accurate numerical predictions of cooling air flows in laptop and notebook computers remain a challenging task.

Localized modelling and feedback control of linear instabilities in 2-D wall bounded shear flows

NASA Astrophysics Data System (ADS)

Tol, Henry; Kotsonis, Marios; de Visser, Coen

2016-11-01

A new approach is presented for control of instabilities in 2-D wall bounded shear flows described by the linearized Navier-Stokes equations (LNSE). The control design accounts both for spatially localized actuators/sensors and the dominant perturbation dynamics in an optimal control framework. An inflow disturbance model is proposed for streamwise instabilities that drive laminar-turbulent transition. The perturbation modes that contribute to the transition process can be selected and are included in the control design. A reduced order model is derived from the LNSE that captures the input-output behavior and the dominant perturbation dynamics. This model is used to design an optimal controller for suppressing the instability growth. A 2-D channel flow and a 2-D boundary layer flow over a flat plate are considered as application cases. Disturbances are generated upstream of the control domain and the resulting flow perturbations are estimated/controlled using wall shear measurements and localized unsteady blowing and suction at the wall. It will be shown that the controller is able to cancel the perturbations and is robust to unmodelled disturbances.

Wall shear stress characterization of a 3D bluff-body separated flow

NASA Astrophysics Data System (ADS)

Fourrié, Grégoire; Keirsbulck, Laurent; Labraga, Larbi

2013-10-01

Efficient flow control strategies aimed at reducing the aerodynamic drag of road vehicles require a detailed knowledge of the reference flow. In this work, the flow around the rear slanted window of a generic car model was experimentally studied through wall shear stress measurements using an electrochemical method. The mean and fluctuating wall shear stress within the wall impact regions of the recirculation bubble and the main longitudinal vortex structures which develop above the rear window are presented. Correlations allow a more detailed characterization of the recirculation phenomenon within the separation bubble. In the model symmetry plane the recirculation structure compares well with simpler 2D configurations; specific lengths, flapping motion and shedding of large-scale vortices are observed, these similarities diminish when leaving the middle plane due to the strong three-dimensionality of the flow. A specific attention is paid to the convection processes occurring within the recirculation: a downstream convection velocity is observed, in accordance with 2D recirculations from the literature, and an upstream convection is highlighted along the entire bubble length which has not been underlined in some previous canonical configurations.

Shear-induced desorption of isolated polymer molecules from a planar wall

NASA Astrophysics Data System (ADS)

Dutta, Sarit; Dorfman, Kevin; Kumar, Satish

2014-03-01

Shear-induced desorption of isolated polymer molecules is studied using Brownian dynamics simulations. The polymer molecules are modeled as freely jointed bead-spring chains interacting with a planar wall via a short-range potential. The simulations include both intrachain and chain-wall hydrodynamic interactions. Shear flow is found to cause chain flattening, resulting at low shear rates in an increased fraction of chain segments bound to the wall. However, above a critical shear rate the chains desorb completely. The desorption process is nucleated by random protrusions in the shear gradient direction which evolve under the combined effect of drag, hydrodynamic interaction, and vorticity-induced rotation, and subsequently lead to recapture. Above the critical shear rate, these protrusions grow in length until the entire chain is peeled off the wall. For free-draining chains, the protrusions are not sustained and no desorption is observed even at shear rates much higher than the critical value. These simulations can help in interpreting experiments on shear-induced desorption of polymer films and brushes.

NMRI Measurements of Flow of Granular Mixtures

NASA Technical Reports Server (NTRS)

Nakagawa, Masami; Waggoner, R. Allen; Fukushima, Eiichi

1996-01-01

We investigate complex 3D behavior of granular mixtures in shaking and shearing devices. NMRI can non-invasively measure concentration, velocity, and velocity fluctuations of flows of suitable particles. We investigate origins of wall-shear induced convection flow of single component particles by measuring the flow and fluctuating motion of particles near rough boundaries. We also investigate if a mixture of different size particles segregate into their own species under the influence of external shaking and shearing disturbances. These non-invasive measurements will reveal true nature of convecting flow properties and wall disturbance. For experiments in a reduced gravity environment, we will design a light weight NMR imager. The proof of principle development will prepare for the construction of a complete spaceborne system to perform experiments in space.

Simulation of High-Speed Droplet Impact Against Dry Substrates with Partial Velocity Slip

NASA Astrophysics Data System (ADS)

Kondo, Tomoki; Ando, Keita

2017-11-01

High-speed droplet impact can be used to clean substrates such as silicon wafers. Radially spreading shear flow after the impact may allow for mechanically removing contaminant particles at substrate surfaces. Since it is a big challenge to experimentally explore such complicated flow that exhibits contact line motion and water hammer, its flow feature is not well understood. Here, we aim to numerically evaluate shear flow caused by the impact of a spherical water droplet (of submillimeter sizes) at high speed (up to 50 m/s) against a dry rigid wall. We model the flow based on compressible Navier-Stokes equations with Stokes' hypothesis and solve them by a high-order-accurate finite volume method equipped with shock and interface capturing. To treat the motion of a contact line between the three phases (the droplet, the rigid wall, and the ambient air) in a robust manner, we permit velocity slip at the wall with Navier's model, for wall slip is known to come into play under steep velocity gradients that can arise from high-speed droplet impact. In our presentation, we will examine radially spreading flow after the droplet impact and the resulting wall shear stress generation from the simulation. This work was supported by JSPS KAKENHI Grant Number JP17J02211.

Velocity shear, turbulent saturation, and steep plasma gradients in the scrape-off layer of inner-wall limited tokamaks

DOE PAGES

Halpern, Federico D.; Ricci, Paolo

2016-12-19

The narrow power decay-length (λ q), recently found in the scrape-off layer (SOL) of inner wall limited (IWL) discharges in tokamaks, is studied using 3D, flux-driven, global two fluid turbulence simulations. The formation of the steep plasma profiles is found to arise due to radially sheared E×B poloidal flows. A complex interaction between sheared flows and parallel plasma currents outflowing into the sheath regulates the turbulent saturation, determining the transport levels. We quantify the effects of sheared flows, obtaining theoretical estimates in agreement with our non-linear simulations. As a result, analytical calculations suggest that the IWL λ q is roughlymore » equal to the turbulent correlation length.« less

Simulation of blood flow in a small-diameter vascular graft model with a swirl (spiral) flow guider.

PubMed

Zhang, ZhiGuo; Fan, YuBo; Deng, XiaoYan; Wang, GuiXue; Zhang, He; Guidoin, Robert

2008-10-01

Small-diameter vascular grafts are in large demand for coronary and peripheral bypass procedures, but present products still fail in long-term clinical application. In the present communication, a new type of small-diameter graft with a swirl flow guider was proposed to improve graft patency rate. Flow pattern in the graft was simulated numerically and compared with that in a conventional graft. The numerical results revealed that the swirl flow guider could indeed make the blood flow rotate in the new graft. The swirling flow distal to the flow guider significantly altered the flow pattern in the new graft and the velocity profiles were re-distributed. Due to the swirling flow, the blood velocity near the vessel wall and wall shear rate were greatly enhanced. We believe that the increased blood velocity near the wall and the wall shear rate can impede the occurrence of acute thrombus formation and intimal hyperplasia, hence can improve the graft patency rate for long-term clinical use.

Role of endothelium sensitivity to shear stress in noradrenaline-induced constriction of feline femoral arterial bed under constant flow and constant pressure perfusions.

PubMed

Kartamyshev, Sergey P; Balashov, Sergey A; Melkumyants, Arthur M

2007-01-01

The effect of shear stress at the endothelium in the attenuation of the noradrenaline-induced constriction of the femoral vascular bed perfused at a constant blood flow was investigated in 16 anesthetized cats. It is known that the adrenergic vasoconstriction of the femoral vascular bed is considerably greater at a constant pressure perfusion than at a constant blood flow. This difference may depend on the ability of the endothelium to relax smooth muscle in response to an increase in wall shear stress. Since the shear stress is directly related to the blood flow and inversely related to the third power of vessel diameter, vasoconstriction at a constant blood flow increases the wall shear stress that is the stimulus for smooth muscle relaxation opposing constriction. On the other hand, at a constant perfusion pressure, vasoconstriction is accompanied by a decrease in flow rate, which prevents a wall shear stress increase. To reveal the effect of endothelial sensitivity to shear stress, we compared noradrenaline-induced changes in total and proximal arterial resistances during perfusion of the hind limb at a constant blood flow and at a constant pressure in vessels with intact and injured endothelium. We found that in the endothelium-intact bed the same concentration of noradrenaline at a constant flow caused an increase in overall vascular peripheral resistance that was half as large as at a constant perfusion pressure. This difference is mainly confined to the proximal arterial vessels (arteries and large arterioles) whose resistance at a constant flow increased only 0.19 +/- 0.03 times compared to that at a constant pressure. The removal of the endothelium only slightly increased constrictor responses at the perfusion under a constant pressure (noradrenaline-induced increases of both overall and proximal arterial resistance augmented by 12%), while the responses of the proximal vessels at a constant flow became 4.7 +/- 0.4 times greater than in the endothelium-intact bed. A selective blockage of endothelium sensitivity to shear stress using a glutaraldehyde dimer augmented the constrictor responses of the proximal vessels at a constant flow 4.6-fold (+/-0.3), but had no significant effect on the responses at a constant pressure. These results are consistent with the conclusion that the difference in constrictor responses at constant flow and pressure perfusions depends mainly on the smooth muscle relaxation caused by increased wall shear stress. Copyright (c) 2007 S. Karger AG, Basel.

Turbulent structures in wall-bounded shear flows observed via three-dimensional numerical simulators. [using the Illiac 4 computer

NASA Technical Reports Server (NTRS)

Leonard, A.

1980-01-01

Three recent simulations of tubulent shear flow bounded by a wall using the Illiac computer are reported. These are: (1) vibrating-ribbon experiments; (2) study of the evolution of a spot-like disturbance in a laminar boundary layer; and (3) investigation of turbulent channel flow. A number of persistent flow structures were observed, including streamwise and vertical vorticity distributions near the wall, low-speed and high-speed streaks, and local regions of intense vertical velocity. The role of these structures in, for example, the growth or maintenance of turbulence is discussed. The problem of representing the large range of turbulent scales in a computer simulation is also discussed.

Dynamics of liquid slug using particle image velocimetry technique

NASA Astrophysics Data System (ADS)

Siddiqui, M. I.; Aziz, A. Rashid A.; Heikal, M. R.

2016-11-01

Two phase liquid-gas slug flow is a source of vibration and fatigue on pipe walls and downstream equipment. This paper examines the effect of inlet conditions on the stream-wise velocity profiles and on the shear stresses induced by the liquid phase on the pipe wall during the slug flow. Instantaneous velocity vector fields of the liquid-gas (water-air) slug flow regime were obtained using particle image velocimetry (PIV) technique at various inlet conditions. A 6-m long Plexiglas pipe having an internal diameter 74-mm with a slight inclination of about 1.16° was considered for the visualization of the flow pattern. Test section was employed at a point 3.5m from the inlet, mounted with optical correction box filled with water to minimize the curvature effect of pipe on the PIV snapshots. Stream-wise velocity profiles are obtained at the wake of the liquid slug and the effect of inlet conditions were analyzed. A direct relationship was observed in between superficial gas velocity and the liquid stream-wise velocity at wake section of the slug flow. Further, the lower wall shear stresses were obtained using PIV velocity profiles at liquid film and the slug wake sections in a unit slug. The wall shear stress remained higher in the liquid slugy body as compared to the liquid film. Moreover, an increase in the wall shear stress was observed by increasing the gas superficial velocities.

Mathematical modeling of pulsatile flow of non-Newtonian fluid in stenosed arteries

NASA Astrophysics Data System (ADS)

Sankar, D. S.; Lee, Usik

2009-07-01

The pulsatile flow of blood through mild stenosed artery is studied. The effects of pulsatility, stenosis and non-Newtonian behavior of blood, treating the blood as Herschel-Bulkley fluid, are simultaneously considered. A perturbation method is used to analyze the flow. The expressions for the shear stress, velocity, flow rate, wall shear stress, longitudinal impedance and the plug core radius have been obtained. The variations of these flow quantities with different parameters of the fluid have been analyzed. It is found that, the plug core radius, pressure drop and wall shear stress increase with the increase of yield stress or the stenosis height. The velocity and the wall shear stress increase considerably with the increase in the amplitude of the pressure drop. It is clear that for a given value of stenosis height and for the increasing values of the stenosis shape parameter from 3 to 6, there is a sharp increase in the impedance of the flow and also the plots are skewed to the right-hand side. It is observed that the estimates of the increase in the longitudinal impedance increase with the increase of the axial distance or with the increase of the stenosis height. The present study also brings out the effects of asymmetric of the stenosis on the flow quantities.

Assessment of shear stress related parameters in the carotid bifurcation using mouse-specific FSI simulations.

PubMed

De Wilde, David; Trachet, Bram; Debusschere, Nic; Iannaccone, Francesco; Swillens, Abigail; Degroote, Joris; Vierendeels, Jan; De Meyer, Guido R Y; Segers, Patrick

2016-07-26

The ApoE(-)(/)(-) mouse is a common small animal model to study atherosclerosis, an inflammatory disease of the large and medium sized arteries such as the carotid artery. It is generally accepted that the wall shear stress, induced by the blood flow, plays a key role in the onset of this disease. Wall shear stress, however, is difficult to derive from direct in vivo measurements, particularly in mice. In this study, we integrated in vivo imaging (micro-Computed Tomography-µCT and ultrasound) and fluid-structure interaction (FSI) modeling for the mouse-specific assessment of carotid hemodynamics and wall shear stress. Results were provided for 8 carotid bifurcations of 4 ApoE(-)(/)(-) mice. We demonstrated that accounting for the carotid elasticity leads to more realistic flow waveforms over the complete domain of the model due to volume buffering capacity in systole. The 8 simulated cases showed fairly consistent spatial distribution maps of time-averaged wall shear stress (TAWSS) and relative residence time (RRT). Zones with reduced TAWSS and elevated RRT, potential indicators of atherosclerosis-prone regions, were located mainly at the outer sinus of the external carotid artery. In contrast to human carotid hemodynamics, no flow recirculation could be observed in the carotid bifurcation region. Copyright © 2015 Elsevier Ltd. All rights reserved.

Analysis of a dusty wall jet

NASA Technical Reports Server (NTRS)

Lim, Hock-Bin; Roberts, Leonard

1991-01-01

An analysis is given for the entrainment of dust into a turbulent radial wall jet. Equations are solved based on incompressible flow of a radial wall jet into which dust is entrained from the wall and transported by turbulent diffusion and convection throughout the flow. It is shown that the resulting concentration of dust particles in the flow depends on the difference between the applied shear stress at the surface and the maximum level of shear stress that the surface can withstand (varies as rho(sub d)a(sub g)D) i.e., the pressure due to the weight of a single layer of dust. The analysis is expected to have application to the downflow that results from helicopter and VTOL aircraft.

Lattice Boltzmann simulation of shear-induced particle migration in plane Couette-Poiseuille flow: Local ordering of suspension

NASA Astrophysics Data System (ADS)

Chun, Byoungjin; Kwon, Ilyoung; Jung, Hyun Wook; Hyun, Jae Chun

2017-12-01

The shear-induced migration of concentrated non-Brownian monodisperse suspensions in combined plane Couette-Poiseuille (C-P) flows is studied using a lattice Boltzmann simulation. The simulations are mainly performed for a particle volume fraction of ϕbulk = 0.4 and H/a = 44.3, 23.3, where H and a denote the channel height and radius of suspended particles, respectively. The simulation method is validated in two simple flows, plane Poiseuille and plane Couette flows. In the Poiseuille flow, particles migrate to the mid-plane of the channel where the local concentration is close to the limit of random-close-packing, and a random structure is also observed at the plane. In the Couette flow, the particle distribution remains in the initial uniform distribution. In the combined C-P flows, the behaviors of migration are categorized into three groups, namely, Poiseuille-dominant, Couette-dominant, and intermediate regimes, based on the value of a characteristic force, G, where G denotes the relative magnitude of the body force (P) against the wall-driving force (C). With respect to the Poiseuille-dominant regime, the location of the maximum concentration is shifted from the mid-plane to the lower wall moving in the same direction as the external body force, when G decreases. With respect to the Couette-dominant regime, the behavior is similar to that of a simple shear flow with the exception that a slightly higher concentration of particles is observed near the lower wall. However, with respect to the intermediate value of G, several layers of highly ordered particles are unexpectedly observed near the lower wall where the plane of maximum concentration is located. The locally ordered structure is mainly due to the lateral migration of particles and wall confinement. The suspended particles migrate toward a vanishingly small shear rate at the wall, and they are consequently layered into highly ordered two-dimensional structures at the high local volume fraction.

Changes in blood flow due to stented parent artery expansion in an intracranial aneurysm.

PubMed

Mori, Futoshi; Ohta, Makoto; Matsuzawa, Teruo

2015-01-01

Stent placement is thought to obstruct the inflow of blood to an aneurysm. However, we introduced parent artery expansion and demonstrated that this may reduce the blood flow by the stent. In our previous study using idealized shapes, the results showed that flow reduction was greater than 22.2%, even if the expansion rate was only 6%. Furthermore, the parent artery expansion is predominantly caused by the effect of flow reduction as compared to that of flow reduction due to the obstruction of flow under stent placement. However, a realistic shape is complex and the blood flow also becomes complex flow. It is not understood whether the results of flow in the idealized shape are reflective of flow from a realistic 3D model. Therefore, we examined the effect of parent artery expansion using a realistic model. The aim is to clarify the effects of parent artery expansion on inflow rate, wall shear stress, and oscillatory shear index. We used a patient-specific geometry of a human internal carotid artery with an aneurysm. The geometry of parent artery expansion due to oversized stent constructed based on the voronoi diagram. We performed calculations in the unsteady-state situations using constructed models. The complexity of the flow in the aneurysm decreases in case of expanded parent artery. The inflow rate decreases by 33.6% immediately after parent artery expansion alone without a stent. The effect of the parent artery expansion on flow reduction is larger than that of the obstruction flow by stent placement. In addition, wall shear stress and oscillatory shear index on the aneurysm wall decrease by change in blood flow due to the parent artery expansion. The effects of the parent artery expansion in a realistic aneurysm model with different stent lengths were evaluated on the basis of a numerical simulation. Although the flow was complex, the parent artery expansion with stent reduces the inflow to the aneurysm and wall shear stress and oscillatory shear index on the aneurysm. Therefore, we suggest that changes in the blood flow because of the parent artery expansion may be identified and, sometimes, is more effective than the obstruction flow due to the stent placement.

Analysis of flow patterns in a patient-specific aortic dissection model.

PubMed

Cheng, Z; Tan, F P P; Riga, C V; Bicknell, C D; Hamady, M S; Gibbs, R G J; Wood, N B; Xu, X Y

2010-05-01

Aortic dissection is the most common acute catastrophic event affecting the thoracic aorta. The majority of patients presenting with an uncomplicated type B dissection are treated medically, but 25% of these patients develop subsequent aneurysmal dilatation of the thoracic aorta. This study aimed at gaining more detailed knowledge of the flow phenomena associated with this condition. Morphological features and flow patterns in a dissected aortic segment of a presurgery type B dissection patient were analyzed based on computed tomography images acquired from the patient. Computational simulations of blood flow in the patient-specific model were performed by employing a correlation-based transitional version of Menter's hybrid k-epsilon/k-omega shear stress transport turbulence model implemented in ANSYS CFX 11. Our results show that the dissected aorta is dominated by locally highly disturbed, and possibly turbulent, flow with strong recirculation. A significant proportion (about 80%) of the aortic flow enters the false lumen, which may further increase the dilatation of the aorta. High values of wall shear stress have been found around the tear on the true lumen wall, perhaps increasing the likelihood of expanding the tear. Turbulence intensity in the tear region reaches a maximum of 70% at midsystolic deceleration phase. Incorporating the non-Newtonian behavior of blood into the same transitional flow model has yielded a slightly lower peak wall shear stress and higher maximum turbulence intensity without causing discernible changes to the distribution patterns. Comparisons between the laminar and turbulent flow simulations show a qualitatively similar distribution of wall shear stress but a significantly higher magnitude with the transitional turbulence model.

Heat transfer, velocity-temperature correlation, and turbulent shear stress from Navier-Stokes computations of shock wave/turbulent boundary layer interaction flows

NASA Technical Reports Server (NTRS)

Wang, C. R.; Hingst, W. R.; Porro, A. R.

1991-01-01

The properties of 2-D shock wave/turbulent boundary layer interaction flows were calculated by using a compressible turbulent Navier-Stokes numerical computational code. Interaction flows caused by oblique shock wave impingement on the turbulent boundary layer flow were considered. The oblique shock waves were induced with shock generators at angles of attack less than 10 degs in supersonic flows. The surface temperatures were kept at near-adiabatic (ratio of wall static temperature to free stream total temperature) and cold wall (ratio of wall static temperature to free stream total temperature) conditions. The computational results were studied for the surface heat transfer, velocity temperature correlation, and turbulent shear stress in the interaction flow fields. Comparisons of the computational results with existing measurements indicated that (1) the surface heat transfer rates and surface pressures could be correlated with Holden's relationship, (2) the mean flow streamwise velocity components and static temperatures could be correlated with Crocco's relationship if flow separation did not occur, and (3) the Baldwin-Lomax turbulence model should be modified for turbulent shear stress computations in the interaction flows.

Haemodynamic predictors of a penetrating atherosclerotic ulcer rupture using fluid–structure interaction analysis

PubMed Central

D'Ancona, Giuseppe; Amaducci, Andrea; Rinaudo, Antonino; Pasta, Salvatore; Follis, Fabrizio; Pilato, Michele; Baglini, Roberto

2013-01-01

We present preliminary data on the flow-induced haemodynamic and structural loads exerted on a penetrating atherosclerotic aortic ulcer (PAU). Specifically, one-way fluid–structure interaction analysis was performed on the aortic model reconstructed from a 66-year-old male patient with a PAU that evolved into an intramural haematoma and rupture of the thoracic aorta. The results show that elevated blood pressure (117 mmHg) and low flow velocity at the aortic wall (0.15 m/s2) occurred in the region of the PAU. We also found a low value of time-averaged wall shear stress (1.24 N/m2) and a high value of the temporal oscillation in the wall shear stress (oscillatory shear index = 0.13) in the region of the PAU. After endovascular treatment, these haemodynamic parameters were distributed uniformly on the luminal surface of the stent graft. These findings suggest that wall shear stress could be considered one of the major haemodynamic factors indicating the structural fragility of the PAU wall, which ultimately lead to PAU growth and rupture. PMID:23736658

Instability-induced ordering, universal unfolding and the role of gravity in granular Couette flow

NASA Astrophysics Data System (ADS)

Alam, Meheboob; Arakeri, V. H.; Nott, P. R.; Goddard, J. D.; Herrmann, H. J.

2005-01-01

Linear stability theory and bifurcation analysis are used to investigate the role of gravity in shear-band formation in granular Couette flow, considering a kinetic-theory rheological model. We show that the only possible state, at low shear rates, corresponds to a "plug" near the bottom wall, in which the particles are densely packed and the shear rate is close to zero, and a uniformly sheared dilute region above it. The origin of such plugged states is shown to be tied to the spontaneous symmetry-breaking instabilities of the gravity-free uniform shear flow, leading to the formation of ordered bands of alternating dilute and dense regions in the transverse direction, via an infinite hierarchy of pitchfork bifurcations. Gravity plays the role of an "imperfection", thus destroying the "perfect" bifurcation structure of uniform shear. The present bifurcation problem admits universal unfolding of pitchfork bifurcations which subsequently leads to the formation of a sequence of a countably infinite number of "isolas", with the solution structures being a modulated version of their gravity-free counterpart. While the solution with a plug near the bottom wall looks remarkably similar to the shear-banding phenomenon in dense slow granular Couette flows, a "floating" plug near the top wall is also a solution of these equations at high shear rates. A two-dimensional linear stability analysis suggests that these floating plugged states are unstable to long-wave travelling disturbances.The unique solution having a bottom plug can also be unstable to long waves, but remains stable at sufficiently low shear rates. The implications and realizability of the present results are discussed in the light of shear-cell experiments under "microgravity" conditions.

The Relationship Between Pulsatile Flow Impingement and Intraluminal Thrombus Deposition in Abdominal Aortic Aneurysms.

PubMed

Lozowy, Richard J; Kuhn, David C S; Ducas, Annie A; Boyd, April J

2017-03-01

Direct numerical simulations were performed on four patient-specific abdominal aortic aneurysm (AAA) geometries and the resulting pulsatile blood flow dynamics were compared to aneurysm shape and correlated with intraluminal thrombus (ILT) deposition. For three of the cases, turbulent vortex structures impinged/sheared along the anterior wall and along the posterior wall a zone of recirculating blood formed. Within the impingement region the AAA wall was devoid of ILT and remote to this region there was an accumulation of ILT. The high wall shear stress (WSS) caused by the impact of vortexes is thought to prevent the attachment of ILT. WSS from impingement is comparable to peak-systolic WSS in a normal-sized aorta and therefore may not damage the wall. Expansion occurred to a greater extent in the direction of jet impingement and the wall-normal force from the continuous impact of vortexes may contribute to expansion. It was shown that the impingement region has low oscillatory shear index (OSI) and recirculation zones can have either low or high OSI. No correlation could be identified between OSI and ILT deposition since different flow dynamics can have similar OSI values.

Experimenatal analysis of the effect of cartilaginous rings on human tracheobronchial flow

NASA Astrophysics Data System (ADS)

Montoya Segnini, Jose; Bocanegra Evans, Humberto; Castillo, Luciano

2016-11-01

We present a set of high-resolution PIV experiments carried out in a refractive index-matched model of a trachea with cartilage rings at Re 2800. Results show a higher vorticity along the walls of the trachea in the model with cartilaginous rings as well as small recirculation areas on the upstream side of the wall cavities created by the rings. Furthermore, the ringed model experiences higher shear stress in the trachea due to the sudden change in the wall position created by the rings. Additionally, small recirculation areas are identified in the cavities between rings. For the smooth model, a stronger separation bubble is observed at the bronchi entrance, generating a stronger shear layer and increasing the wall shear stress on the bottom bronchi wall. The differences observed go against the notion that the main airway, i.e. trachea and main bronchi, may be modeled as smooth. Our results suggest that cartilage rings will have an impact on the wall shear stress and may affect particle deposition, which is of importance in inhaled drug delivery and pollutant deposition in the airway. Additionally, the effects introduced by the rings may change the flow characteristics in further generations.

Quantifying colloidal particle bands and their formation in combined electroosmotic and Poiseuille flow

NASA Astrophysics Data System (ADS)

Yee, Andrew; Cevheri, Necmettin; Yoda, Minami

2015-11-01

Recently, we have shown that suspended radii a = 245 nm particles flowing through a microchannel driven by the combination of a dc electric field and pressure gradient (where the resulting electroosmotic and shear flows are in opposite directions) are attracted to the wall at low electric field magnitude | E | , then assemble into concentrated bands that only exist within a few μm of the wall above a threshold value of | E | , | Ecr | . The ~ 6 μ m wide bands are aligned with the flow direction and are roughly periodic along the cross-stream direction. This talk focuses on quantitative characterization of these bands, for example how | Ecr | , the time required for bands to form after applying the electric field To, and the number of bands depend upon parameters such as particle volume fraction φ, shear rate γ˙ , | E | , and a. The dynamics of the particles within the bands are visualized by imaging a mixture of particles with different fluorescent labels. The visualizations show that the particles are in a liquid state within these bands, and suggest that the particles nearest the wall move in the direction of the electroosmotic flow, while those farther from the wall move in the direction of the shear flow. Supported by NSF.

Flow-induced adhesion of shear-activated polymers to a substrate

NASA Astrophysics Data System (ADS)

Hoore, Masoud; Rack, Kathrin; Fedosov, Dmitry A.; Gompper, Gerhard

2018-02-01

Adhesion of polymers and proteins to substrates plays a crucial role in many technological applications and biological processes. A prominent example is the von Willebrand factor (VWF) protein, which is essential in blood clotting as it mediates adhesion of blood platelets to the site of injury at high shear rates. VWF is activated by flow and is able to bind efficiently to damaged vessel walls even under extreme flow-stress conditions; however, its adhesion is reversible when the flow strength is significantly reduced or the flow is ceased. Motivated by the properties and behavior of VWF in flow, we investigate adhesion of shear-activated polymers to a planar wall in flow and whether the adhesion is reversible under flow stasis. The main ingredients of the polymer model are cohesive inter-monomer interactions, a catch bond with the adhesive surface, and the shear activation/deactivation of polymer adhesion correlated with its stretching in flow. The cohesive interactions within the polymer maintain a globular conformation under low shear stresses and allow polymer stretching if a critical shear rate is exceeded, which is directly associated with its activation for adhesion. Our results show that polymer adhesion at high shear rates is significantly stabilized by catch bonds, while at the same time they also permit polymer dissociation from a surface at low or no flow stresses. In addition, the activation/deactivation mechanism for adhesion plays a crucial role in the reversibility of its adhesion. These observations help us better understand the adhesive behavior of VWF in flow and interpret its adhesion malfunctioning in VWF-related diseases.

Inflectional instabilities in the wall region of bounded turbulent shear flows

NASA Technical Reports Server (NTRS)

Swearingen, Jerry D.; Blackwelder, Ron F.; Spalart, Philippe R.

1987-01-01

The primary thrust of this research was to identify one or more mechanisms responsible for strong turbulence production events in the wall region of bounded turbulent shear flows. Based upon previous work in a transitional boundary layer, it seemed highly probable that the production events were preceded by an inflectional velocity profile which formed on the interface between the low-speed streak and the surrounding fluid. In bounded transitional flows, this unstable profile developed velocity fluctuations in the streamwise direction and in the direction perpendicular to the sheared surface. The rapid growth of these instabilities leads to a breakdown and production of turbulence. Since bounded turbulent flows have many of the same characteristics, they may also experience a similar type of breakdown and turbulence production mechanism.

Shear flow of dense granular materials near smooth walls. I. Shear localization and constitutive laws in the boundary region.

PubMed

Shojaaee, Zahra; Roux, Jean-Noël; Chevoir, François; Wolf, Dietrich E

2012-07-01

We report on a numerical study of the shear flow of a simple two-dimensional model of a granular material under controlled normal stress between two parallel smooth frictional walls moving with opposite velocities ± V. Discrete simulations, which are carried out with the contact dynamics method in dense assemblies of disks, reveal that, unlike rough walls made of strands of particles, smooth ones can lead to shear strain localization in the boundary layer. Specifically, we observe, for decreasing V, first a fluidlike regime (A), in which the whole granular layer is sheared, with a homogeneous strain rate except near the walls, then (B) a symmetric velocity profile with a solid block in the middle and strain localized near the walls, and finally (C) a state with broken symmetry in which the shear rate is confined to one boundary layer, while the bulk of the material moves together with the opposite wall. Both transitions are independent of system size and occur for specific values of V. Transient times are discussed. We show that the first transition, between regimes A and B, can be deduced from constitutive laws identified for the bulk material and the boundary layer, while the second one could be associated with an instability in the behavior of the boundary layer. The boundary zone constitutive law, however, is observed to depend on the state of the bulk material nearby.

Turbulent Boundary Layer on a Cylinder in Axial Flow

DTIC Science & Technology

1988-09-29

finding the wall shea stress. Finally, ft ;hould be noted that the wall shear stress can be found from the streamwrwise gradient of the mornsntum...somewhat butter collapse than inner scaling, suggesting that the outer flow affects events at the wall. By comparison, the burst frequency in a planar

Oscillatory motion based measurement method and sensor for measuring wall shear stress due to fluid flow

DOEpatents

Armstrong, William D [Laramie, WY; Naughton, Jonathan [Laramie, WY; Lindberg, William R [Laramie, WY

2008-09-02

A shear stress sensor for measuring fluid wall shear stress on a test surface is provided. The wall shear stress sensor is comprised of an active sensing surface and a sensor body. An elastic mechanism mounted between the active sensing surface and the sensor body allows movement between the active sensing surface and the sensor body. A driving mechanism forces the shear stress sensor to oscillate. A measuring mechanism measures displacement of the active sensing surface relative to the sensor body. The sensor may be operated under periodic excitation where changes in the nature of the fluid properties or the fluid flow over the sensor measurably changes the amplitude or phase of the motion of the active sensing surface, or changes the force and power required from a control system in order to maintain constant motion. The device may be operated under non-periodic excitation where changes in the nature of the fluid properties or the fluid flow over the sensor change the transient motion of the active sensor surface or change the force and power required from a control system to maintain a specified transient motion of the active sensor surface.

Turbulent boundary layers with secondary flow

NASA Technical Reports Server (NTRS)

Grushwitz, E.

1984-01-01

An experimental analysis of the boundary layer on a plane wall, along which the flow occurs, whose potential flow lines are curved in plane parallel to the wall is discussed. According to the equation frequently applied to boundary layers in a plane flow, which is usually obtained by using the pulse law, a generalization is derived which is valid for boundary layers with spatial flow. The wall shear stresses were calculated with this equation.

Unsteady behavior of a reattaching shear layer

NASA Technical Reports Server (NTRS)

Driver, D. M.; Seegmiller, H. L.; Marvin, J.

1983-01-01

A detailed investigation of the unsteadiness in a reattaching, turbulent shear layer is reported. Laser-Doppler velocimeter measurements were conditionally sampled on the basis of instantaneous flow direction near reattachment. Conditions of abnormally short reattachment and abnormally long reattachment were considered. Ensemble-averaging of measurements made during these conditions was used to obtain mean velocities and Rreynolds stresses. In the mean flow, conditional streamlines show a global change in flow pattern which correlates with wall-flow direction. This motion can loosely be described as a 'flapping' of the shear layer. Tuft probes show that the flow direction reversals occur quite randomly and are shortlived. Streses shown also vary with the change in flow pattern. Yet, the global'flapping' motion does not appear to contribute significantly to the stress in the flow. A second type of unsteady motion was identified. Spectral analysis of both wall static pressure and streamwise velocity shows that most of the energy in the flow resides in frequencies that are significantly lower than that of the turbulence. The dominant frequency is at a Strouhal number equal to 0.2, which is the characteristic frequency of roll-up and pairing of vortical structure seen in free shear layers. It is conjectured that the 'flapping' is a disorder of the roll-up and pairing process occurring in the shear layer.

Computational Analysis of Intra-Ventricular Flow Pattern Under Partial and Full Support of BJUT-II VAD.

PubMed

Zhang, Qi; Gao, Bin; Chang, Yu

2017-02-27

BACKGROUND Partial support, as a novel support mode, has been widely applied in clinical practice and widely studied. However, the precise mechanism of partial support of LVAD in the intra-ventricular flow pattern is unclear. MATERIAL AND METHODS In this study, a patient-specific left ventricular geometric model was reconstructed based on CT data. The intra-ventricular flow pattern under 3 simulated conditions - "heart failure", "partial support", and "full support" - were simulated by using fluid-structure interaction (FSI). The blood flow pattern, wall shear stress (WSS), time-average wall shear stress (TAWSS), oscillatory shear index (OSI), and relative residence time (RRT) were calculated to evaluate the hemodynamic effects. RESULTS The results demonstrate that the intra-ventricular flow pattern is significantly changed by the support level of BJUT-II VAD. The intra-ventricular vortex was enhanced under partial support and was eliminated under full support, and the high OSI and RRT regions changed from the septum wall to the cardiac apex. CONCLUSIONS In brief, the support level of the BJUT-II VAD has significant effects on the intra-ventricular flow pattern. The partial support mode of BJUT-II VAD can enhance the intra-ventricular vortex, while the distribution of high OSI and RRT moved from the septum wall to the cardiac apex. Hence, the partial support mode of BJUT-II VAD can provide more benefit for intra-ventricular flow pattern.

Measurement of wall shear stress in chick embryonic heart using optical coherence tomography

NASA Astrophysics Data System (ADS)

Ma, Zhenhe; Dou, Shidan; Zhao, Yuqian; Wang, Yi; Suo, Yanyan; Wang, Fengwen

2015-03-01

The cardiac development is a complicated process affected by genetic and environmental factors. Wall shear stress (WSS) is one of the components which have been proved to influence the morphogenesis during early stages of cardiac development. To study the mechanism, WSS measurement is a step with significant importance. WSS is caused by blood flow imposed on the inner surface of the heart wall and it can be determined by calculating velocity gradients of blood flow in a direction perpendicular to the wall. However, the WSS of the early stage embryonic heart is difficult to measure since the embryonic heart is tiny and beating fast. Optical coherence tomography (OCT) is a non-invasive imaging modality with high spatial and temporal resolution, which is uniquely suitable for the study of early stage embryonic heart development. In this paper, we introduce a method to measure the WSS of early stage chick embryonic heart based on high speed spectral domain optical coherence tomography (SDOCT). 4D (x,y,z,t) scan was performed on the outflow tract (OFT) of HH18 (~3 days of incubation) chick embryonic heart. After phase synchronization, OFT boundary segmentation, and OFT center line calculation, Doppler angle of the blood flow in the OFT can be achieved (This method has been described in previous publications). Combining with the Doppler OCT results, we calculate absolute blood flow velocity distribution in the OFT. The boundary of the OFT was segmented at each cross-sectional structural image, then geometrical center of the OFT can be calculated. Thus, the gradients of blood flow in radial direction can be calculated. This velocity gradient near the wall is termed wall shear rate and the WSS value is proportional to the wall shear rate. Based on this method, the WSS at different heart beating phase are compare. The result demonstrates that OCT is capable of early stage chicken embryonic heart WSS study.

The impact of wall shear stress and pressure drop on the stability of the atherosclerotic plaque.

PubMed

Li, Zhi-Yong; Taviani, Valentina; Gillard, Jonathan H

2008-01-01

Rupture of vulnerable atheromatous plaque in the carotid and coronary arteries often leads to stroke and heart attack respectively. The mechanism of blood flow and plaque rupture in stenotic arteries is still not fully understood. A three dimensional rigid wall model was solved under steady state conditions and unsteady conditions by assuming a time-varying inlet velocity profile to investigate the relative importance of axial forces and pressure drops in arteries with asymmetric stenosis. Flow-structure interactions were investigated for the same geometry and the results were compared with those retrieved with the corresponding 2D cross-section structural models. The Navier-Stokes equations were used as the governing equations for the fluid. The tube wall was assumed hyperelastic, homogeneous, isotropic and incompressible. The analysis showed that the three dimensional behavior of velocity, pressure and wall shear stress is in general very different from that predicted by cross-section models. Pressure drop across the stenosis was found to be much higher than shear stress. Therefore, pressure may be the more important mechanical trigger for plaque rupture other than shear stress, although shear stress is closely related to plaque formation and progression.

Time-Resolved Particle Image Velocimetry Measurements with Wall Shear Stress and Uncertainty Quantification for the FDA Nozzle Model.

PubMed

Raben, Jaime S; Hariharan, Prasanna; Robinson, Ronald; Malinauskas, Richard; Vlachos, Pavlos P

2016-03-01

We present advanced particle image velocimetry (PIV) processing, post-processing, and uncertainty estimation techniques to support the validation of computational fluid dynamics analyses of medical devices. This work is an extension of a previous FDA-sponsored multi-laboratory study, which used a medical device mimicking geometry referred to as the FDA benchmark nozzle model. Experimental measurements were performed using time-resolved PIV at five overlapping regions of the model for Reynolds numbers in the nozzle throat of 500, 2000, 5000, and 8000. Images included a twofold increase in spatial resolution in comparison to the previous study. Data was processed using ensemble correlation, dynamic range enhancement, and phase correlations to increase signal-to-noise ratios and measurement accuracy, and to resolve flow regions with large velocity ranges and gradients, which is typical of many blood-contacting medical devices. Parameters relevant to device safety, including shear stress at the wall and in bulk flow, were computed using radial basis functions. In addition, in-field spatially resolved pressure distributions, Reynolds stresses, and energy dissipation rates were computed from PIV measurements. Velocity measurement uncertainty was estimated directly from the PIV correlation plane, and uncertainty analysis for wall shear stress at each measurement location was performed using a Monte Carlo model. Local velocity uncertainty varied greatly and depended largely on local conditions such as particle seeding, velocity gradients, and particle displacements. Uncertainty in low velocity regions in the sudden expansion section of the nozzle was greatly reduced by over an order of magnitude when dynamic range enhancement was applied. Wall shear stress uncertainty was dominated by uncertainty contributions from velocity estimations, which were shown to account for 90-99% of the total uncertainty. This study provides advancements in the PIV processing methodologies over the previous work through increased PIV image resolution, use of robust image processing algorithms for near-wall velocity measurements and wall shear stress calculations, and uncertainty analyses for both velocity and wall shear stress measurements. The velocity and shear stress analysis, with spatially distributed uncertainty estimates, highlights the challenges of flow quantification in medical devices and provides potential methods to overcome such challenges.

Experimental and numerical investigation of low-drag intervals in turbulent boundary layer

NASA Astrophysics Data System (ADS)

Park, Jae Sung; Ryu, Sangjin; Lee, Jin

2017-11-01

It has been widely investigated that there is a substantial intermittency between high and low drag states in wall-bounded shear flows. Recent experimental and computational studies in a turbulent channel flow have identified low-drag time intervals based on wall shear stress measurements. These intervals are a weak turbulence state characterized by low-speed streaks and weak streamwise vortices. In this study, the spatiotemporal dynamics of low-drag intervals in a turbulent boundary layer is investigated using experiments and simulations. The low-drag intervals are monitored based on the wall shear stress measurement. We show that near the wall conditionally-sampled mean velocity profiles during low-drag intervals closely approach that of a low-drag nonlinear traveling wave solution as well as that of the so-called maximum drag reduction asymptote. This observation is consistent with the channel flow studies. Interestingly, the large spatial stretching of the streak is very evident in the wall-normal direction during low-drag intervals. Lastly, a possible connection between the mean velocity profile during the low-drag intervals and the Blasius profile will be discussed. This work was supported by startup funds from the University of Nebraska-Lincoln.

Influence of vibration on structure rheological properties of a highly concentrated suspension

NASA Astrophysics Data System (ADS)

Ouriev Uriev, Boris N.; Uriev, Naum B.

2005-08-01

The influence of mechanical vibration on the flow properties of a highly concentrated multiphase food system is explored in this work. An experimental set-up was designed and adapted to a conventional rotational rheometer with precise rheological characterization capability. A number of calibration tests were performed prior to fundamental experiments with a highly concentrated chocolate suspension. Also, the prediction of wall slippage in shear flow under vibration was evaluated. Analysis of the boundary conditions shows that no side effects such as wall slippage or the Taylor effect were present during the shear experiment under vibration. It was found that superposition of mechanical vibration and shear flow radically decreases the shear viscosity. Comparison between reference shear viscosities at specified shear rates and those measured under vibration shows considerable differences in flow properties. Conversion of the behaviour of the concentrated suspension from strongly shear-thinning to Newtonian flow is reported. Also, the appearance of vibration-induced dilatancy as a new phenomenon is described. It is suggested to relate such phenomena to the non-equilibrium between structure formation and disintegration under vibration and hydrodynamic forces of shear flow. The influence of vibration on structure formation can be well observed during measurement of the yield value of the chocolate suspension under vibration. Comparison with reference data shows how sensitive the structure of the concentrated suspension is to vibration in general. The effects and observations revealed provide a solid basis for further fundamental investigations of structure formation regularities in the flow of any highly concentrated system. The results also show the technological potential for non-conventional treatment of concentrated, multiphase systems.

Applications of a new wall function to turbulent flow computations

NASA Astrophysics Data System (ADS)

Chen, Y. S.

1986-01-01

A new wall function approach is developed based on a wall law suitable for incompressible turbulent boundary layers under strong adverse pressure gradients. This wall law was derived from a one-dimensional analysis of the turbulent kinetic energy equation with gradient diffusion concept employed in modeling the near-wall shear stress gradient. Numerical testing cases for the present wall functions include turbulent separating flows around an airfoil and turbulent recirculating flows in several confined regions. Improvements on the predictions using the present wall functions are illustrated. For cases of internal recirculating flows, one modification factor for improving the performance of the k-epsilon turbulence model in the flow recirculation regions is also included.

In vivo vascular flow profiling combined with optical tweezers based blood routing

NASA Astrophysics Data System (ADS)

Meissner, Robert; Sugden, Wade W.; Siekmann, Arndt F.; Denz, Cornelia

2017-07-01

In vivo wall shear rate is quantified during zebrafish development using particle image velocimetry for biomedical diagnosis and modeling of artificial vessels. By using brightfield microscopy based high speed video tracking we can resolve single heart-beat cycles of blood flow in both space and time. Maximum blood flow velocities and wall shear rates are presented for zebrafish at two and three days post fertilization. By applying biocompatible optical tweezers as an Optical rail we present rerouting of red blood cells in vivo. With purely light-driven means we are able to compensate the lack of proper red blood cell blood flow in so far unperfused capillaries.

Development of a MEMS shear stress sensor for use in wind tunnel applications

NASA Astrophysics Data System (ADS)

Barnard, Casey; Meloy, Jessica; Sheplak, Mark; Interdisciplinary Microsystems Group Team

2013-11-01

The measurement of mean and fluctuating wall shear-stress in laminar, transitional, and turbulent boundary layers and channel flows has applications both in industry and the scientific community. Currently there is no method for time resolved, direct measurement of wall shear stress at the spatial and temporal scales of turbulent flow structures inside model testing facilities. To address this need, a silicon micromachined differential capacitance shear stress sensor system has been developed. Mean measurements are enabled by custom synchronous modulation/demodulation circuitry, which allows for measurement of both magnitude and phase of incident wall shear stress. Sizes of the largest device features are on the order of relevant viscous length scales, to minimize flow disturbance and provide a hydraulically smooth sensing surface. Static calibration is performed in a flow cell setup, and an acoustic plane wave tube is used for dynamic response data. Normalized sensitivity of 1.34 mV/V/Pa has been observed over a bandwidth of 4.8 kHz, with a minimum detectable signal of 6.5 mPa. Initial results show qualitative agreement with contemporary measurement techniques. The design, fabrication, support electronics, characterization, and preliminary experimental performance of this sensor will be presented. The support of NASA SFW-NRA NNX11AI30A, AFOSR grant #FA 9550-12-1-0469, and Sandia Campus Executive Fellowship are gratefully acknowledged.

Abdominal Aortic Hemodynamics in Intermittent Claudication Patients at Rest and During Dynamic Pedaling Exercise

PubMed Central

Cheng, Christopher P.; Taylor, Charles A.; Dalman, Ronald L.

2015-01-01

Introduction Lower extremity exercise has been shown to eliminate adverse hemodynamics conditions, such as low and oscillating blood flow and wall shear stress, in the abdominal aortas of healthy young and older adults. Methods We use cine phase-contrast magnetic resonance imaging and a custom MRI-compatible exercise cycle to quantify hemodynamic changes due to pedaling exercise in patients diagnosed with intermittent claudication. Results and Conclusions With only an average heart increase of 35±18% and exercise workload of 36±16 Watts, the patients experienced approximately 3- and 6-fold increases in blood flow, and 4- and 16-fold increases in wall shear stress at the supraceliac and infrarenal aortic locations, respectively. Also, all oscillations in flow and shear stress at rest were eliminated with exercise. Claudication patients experience 3 to 4-fold lower oscillations in flow and shear stress at rest as compared to healthy age-matched controls, likely due to reduced distal arterial compliance as a result of distal atherosclerosis. The magnitude of flow and shear oscillatory indices may be good indicators of distal arterial compliance and health, and may provide predictive power for the efficacy of focal interventions. PMID:26315797

Elastic turbulence in entangled semi-dilute DNA solutions measured with optical coherence tomography velocimetry.

PubMed

Malm, A V; Waigh, T A

2017-04-26

The flow instabilities of solutions of high molecular weight DNA in the entangled semi-dilute concentration regime were investigated using optical coherence tomography velocimetry, a technique that provides high spatial (probe volumes of 3.4 pL) and temporal resolution (sub μs) information on the flow behaviour of complex fluids in a rheometer. The velocity profiles of the opaque DNA solutions (high and low salt) were measured as a function of the distance across the gap of a parallel plate rheometer, and their evolution over time was measured. At lower DNA concentrations and low shear rates, the velocity fluctuations were well described by Gaussian functions and the velocity gradient was uniform across the rheometer gap, which is expected for Newtonian flows. As the DNA concentration and shear rate were increased there was a stable wall slip regime followed by an evolving wall slip regime, which is finally followed by the onset of elastic turbulence. Strain localization (shear banding) is observed on the boundaries of the flows at intermediate shear rates, but decreases in the high shear elastic turbulence regime, where bulk strain localization occurs. A dynamic phase diagram for non-linear flow was created to describe the different behaviours.

Rôle of contrast media viscosity in altering vessel wall shear stress and relation to the risk of contrast extravasations.

PubMed

Sakellariou, Sophia; Li, Wenguang; Paul, Manosh C; Roditi, Giles

2016-12-01

Iodinated contrast media (CM) are the most commonly used injectables in radiology today. A range of different media are commercially available, combining various physical and chemical characteristics (ionic state, osmolality, viscosity) and thus exhibiting distinct in vivo behaviour and safety profiles. In this paper, numerical simulations of blood flow with contrast media were conducted to investigate the effects of contrast viscosity on generated vessel wall shear stress and vessel wall pressure to elucidate any possible relation to extravasations. Five different types of contrast for Iodine fluxes ranging at 1.5-2.2gI/s were modelled through 18G and 20G cannulae placed in an ideal vein at two different orientation angles. Results demonstrate that the least viscous contrast media generate the least maximum wall shear stress as well as the lowest total pressure for the same flow rate. This supports the empirical clinical observations and hypothesis that more viscous contrast media are responsible for a higher percentage of contrast extravasations. In addition, results support the clinical hypothesis that a catheter tip directed obliquely to the vein wall always produces the highest maximum wall shear stress and total pressure due to impingement of the contrast jet on the vessel wall. Copyright © 2016 IPEM. Published by Elsevier Ltd. All rights reserved.

Large scale structures in a turbulent boundary layer and their imprint on wall shear stress

NASA Astrophysics Data System (ADS)

Pabon, Rommel; Barnard, Casey; Ukeiley, Lawrence; Sheplak, Mark

2015-11-01

Experiments were performed on a turbulent boundary layer developing on a flat plate model under zero pressure gradient flow. A MEMS differential capacitive shear stress sensor with a 1 mm × 1 mm floating element was used to capture the fluctuating wall shear stress simultaneously with streamwise velocity measurements from a hot-wire anemometer traversed in the wall normal direction. Near the wall, the peak in the cross correlation corresponds to an organized motion inclined 45° from the wall. In the outer region, the peak diminishes in value, but is still significant at a distance greater than half the boundary layer thickness, and corresponds to a structure inclined 14° from the wall. High coherence between the two signals was found for the low-frequency content, reinforcing the belief that large scale structures have a vital impact on wall shear stress. Thus, estimation of the wall shear stress from the low-frequency velocity signal will be performed, and is expected to be statistically significant in the outer boundary layer. Additionally, conditionally averaged mean velocity profiles will be presented to assess the effects of high and low shear stress. This material is based upon work supported by the National Science Foundation Graduate Research Fellowship under Grant No. DGE-1315138.

Computational Modeling of Blood Flow in the TrapEase Inferior Vena Cava Filter

DOE Office of Scientific and Technical Information (OSTI.GOV)

Singer, M A; Henshaw, W D; Wang, S L

To evaluate the flow hemodynamics of the TrapEase vena cava filter using three dimensional computational fluid dynamics, including simulated thrombi of multiple shapes, sizes, and trapping positions. The study was performed to identify potential areas of recirculation and stagnation and areas in which trapped thrombi may influence intrafilter thrombosis. Computer models of the TrapEase filter, thrombi (volumes ranging from 0.25mL to 2mL, 3 different shapes), and a 23mm diameter cava were constructed. The hemodynamics of steady-state flow at Reynolds number 600 was examined for the unoccluded and partially occluded filter. Axial velocity contours and wall shear stresses were computed. Flowmore » in the unoccluded TrapEase filter experienced minimal disruption, except near the superior and inferior tips where low velocity flow was observed. For spherical thrombi in the superior trapping position, stagnant and recirculating flow was observed downstream of the thrombus; the volume of stagnant flow and the peak wall shear stress increased monotonically with thrombus volume. For inferiorly trapped spherical thrombi, marked disruption to the flow was observed along the cava wall ipsilateral to the thrombus and in the interior of the filter. Spherically shaped thrombus produced a lower peak wall shear stress than conically shaped thrombus and a larger peak stress than ellipsoidal thrombus. We have designed and constructed a computer model of the flow hemodynamics of the TrapEase IVC filter with varying shapes, sizes, and positions of thrombi. The computer model offers several advantages over in vitro techniques including: improved resolution, ease of evaluating different thrombus sizes and shapes, and easy adaptation for new filter designs and flow parameters. Results from the model also support a previously reported finding from photochromic experiments that suggest the inferior trapping position of the TrapEase IVC filter leads to an intra-filter region of recirculating/stagnant flow with very low shear stress that may be thrombogenic.« less

Fuel Injector With Shear Atomizer

NASA Technical Reports Server (NTRS)

Beal, George W.; Mills, Virgil L.; Smith, Durward B., II; Beacom, William F.

1995-01-01

Atomizer for injecting liquid fuel into combustion chamber uses impact and swirl to break incoming stream of fuel into small, more combustible droplets. Slanted holes direct flow of liquid fuel to stepped cylindrical wall. Impact on wall atomizes liquid. Air flowing past vanes entrains droplets of liquid in swirling flow. Fuel injected at pressure lower than customarily needed.

Vortex dynamics in ruptured and unruptured intracranial aneurysms

NASA Astrophysics Data System (ADS)

Trylesinski, Gabriel; Varble, Nicole; Xiang, Jianping; Meng, Hui

2013-11-01

Intracranial aneurysms (IAs) are potentially devastating pathological dilations of arterial walls that affect 2-5% of the population. In our previous CFD study of 119 IAs, we found that ruptured aneurysms were correlated with complex flow pattern and statistically predictable by low wall shear stress and high oscillatory shear index. To understand flow mechanisms that drive the pathophysiology of aneurysm wall leading to either stabilization or growth and rupture, we aim at exploring vortex dynamics of aneurysmal flow and provide insight into the correlation between the previous predictive morphological parameters and wall hemodynamic metrics. We adopt the Q-criterion definition of coherent structures (CS) and analyze the CS dynamics in aneurysmal flows for both ruptured and unruptured IA cases. For the first time, we draw relevant biological conclusions concerning aneurysm flow mechanisms and pathophysiological outcome. In pulsatile simulations, the coherent structures are analyzed in these 119 patient-specific geometries obtained using 3D angiograms. The images were reconstructed and CFD were performed. Upon conclusion of this work, better understanding of flow patterns of unstable aneurysms may lead to improved clinical outcome.

Shear-Induced Amyloid Formation in the Brain: I. Potential Vascular and Parenchymal Processes.

PubMed

Trumbore, Conrad N

2016-09-06

Shear distortion of amyloid-beta (Aβ) solutions accelerates amyloid cascade reactions that may yield different toxic oligomers than those formed in quiescent solutions. Recent experiments indicate that cerebrospinal fluid (CSF) and interstitial fluid (ISF) containing Aβ flow through narrow brain perivascular pathways and brain parenchyma. This paper suggests that such flow causes shear distortion of Aβ molecules involving conformation changes that may be one of the initiating events in the etiology of Alzheimer's disease. Aβ shearing can occur in or around brain arteries and arterioles and is suggested as the origin of cerebral amyloid angiopathy deposits in cerebrovascular walls. Comparatively low flow rates of ISF within the narrow extracellular spaces (ECS) of the brain parenchyma are suggested as a possible initiating factor in both the formation of neurotoxic Aβ42 oligomers and amyloid fibrils. Aβ42 in slow-flowing ISF can gain significant shear energy at or near the walls of tortuous brain ECS flow paths, promoting the formation of a shear-distorted, excited state hydrophobic Aβ42* conformation. This Aβ42* molecule could possibly be involved in one of two paths, one involving rapid adsorption to a brain membrane surface, ultimately forming neurotoxic oligomers on membranes, and the other ultimately forming plaque within the ECS flow pathways. Rising Aβ concentrations combined with shear at or near critical brain membranes are proposed as contributing factors to Alzheimer's disease neurotoxicity. These hypotheses may be applicable in other neurodegenerative diseases, including tauopathies and alpha-synucleinopathies, in which shear-distorted proteins also may form in the brain ECS.

Two-axis direct fluid shear stress sensor

NASA Technical Reports Server (NTRS)

Bajikar, Sateesh (Inventor); Scott, Michael A. (Inventor); Adcock, Edward E. (Inventor)

2011-01-01

A micro sized multi-axis semiconductor skin friction/wall shear stress induced by fluid flow. The sensor design includes a shear/strain transduction gimble connected to a force collecting plate located at the flow boundary surface. The shear force collecting plate is interconnected by an arm to offset the tortional hinges from the fluid flow. The arm is connected to the shear force collecting plate through dual axis torsional hinges with piezoresistive torsional strain gauges. These gauges are disposed on the tortional hinges and provide a voltage output indicative of applied shear stress acting on the force collection plate proximate the flow boundary surface. Offsetting the torsional hinges creates a force concentration and resolution structure that enables the generation of a large stress on the strain gauge from small shear stress, or small displacement of the collecting plate. The design also isolates the torsional sensors from exposure to the fluid flow.

Impact of wall shear stress on initial bacterial adhesion in rotating annular reactor

PubMed Central

Saur, Thibaut; Morin, Emilie; Habouzit, Frédéric; Bernet, Nicolas

2017-01-01

The objective of this study was to investigate the bacterial adhesion under different wall shear stresses in turbulent flow and using a diverse bacterial consortium. A better understanding of the mechanisms governing microbial adhesion can be useful in diverse domains such as industrial processes, medical fields or environmental biotechnologies. The impact of wall shear stress—four values ranging from 0.09 to 7.3 Pa on polypropylene (PP) and polyvinyl chloride (PVC)—was carried out in rotating annular reactors to evaluate the adhesion in terms of morphological and microbiological structures. A diverse inoculum consisting of activated sludge was used. Epifluorescence microscopy was used to quantitatively and qualitatively characterize the adhesion. Attached bacterial communities were assessed by molecular fingerprinting profiles (CE-SSCP). It has been demonstrated that wall shear stress had a strong impact on both quantitative and qualitative aspects of the bacterial adhesion. ANOVA tests also demonstrated the significant impact of wall shear stress on all three tested morphological parameters (surface coverage, number of objects and size of objects) (p-values < 2.10−16). High wall shear stresses increased the quantity of attached bacteria but also altered their spatial distribution on the substratum surface. As the shear increased, aggregates or clusters appeared and their size grew when increasing the shears. Concerning the microbiological composition, the adhered bacterial communities changed gradually with the applied shear. PMID:28207869

Wall shear stress fixed points in blood flow

NASA Astrophysics Data System (ADS)

Arzani, Amirhossein; Shadden, Shawn

2017-11-01

Patient-specific computational fluid dynamics produces large datasets, and wall shear stress (WSS) is one of the most important parameters due to its close connection with the biological processes at the wall. While some studies have investigated WSS vectorial features, the WSS fixed points have not received much attention. In this talk, we will discuss the importance of WSS fixed points from three viewpoints. First, we will review how WSS fixed points relate to the flow physics away from the wall. Second, we will discuss how certain types of WSS fixed points lead to high biochemical surface concentration in cardiovascular mass transport problems. Finally, we will introduce a new measure to track the exposure of endothelial cells to WSS fixed points.

Numerical investigation of MHD flow of blood and heat transfer in a stenosed arterial segment

NASA Astrophysics Data System (ADS)

Majee, Sreeparna; Shit, G. C.

2017-02-01

A numerical investigation of unsteady flow of blood and heat transfer has been performed with an aim to provide better understanding of blood flow through arteries under stenotic condition. The blood is treated as Newtonian fluid and the arterial wall is considered to be rigid having deposition of plaque in its lumen. The heat transfer characteristic has been analyzed by taking into consideration of the dissipation of energy due to applied magnetic field and the viscosity of blood. The vorticity-stream function formulation has been adopted to solve the problem using implicit finite difference method by developing well known Peaceman-Rachford Alternating Direction Implicit (ADI) scheme. The quantitative profile analysis of velocity, temperature and wall shear stress as well as Nusselt number is carried out over the entire arterial segment. The streamline and temperature contours have been plotted to understand the flow pattern in the diseased artery, which alters significantly in the downstream of the stenosis in the presence of magnetic field. Both the wall shear stress and Nusselt number increases with increasing magnetic field strength. However, wall shear stress decreases and Nusselt number enhances with Reynolds number. The results show that with an increase in the magnetic field strength upto 8 T, does not causes any damage to the arterial wall, but the study is significant for assessing temperature rise during hyperthermic treatment.

Blood Vessel Adaptation with Fluctuations in Capillary Flow Distribution

PubMed Central

Hu, Dan; Cai, David; Rangan, Aaditya V.

2012-01-01

Throughout the life of animals and human beings, blood vessel systems are continuously adapting their structures – the diameter of vessel lumina, the thickness of vessel walls, and the number of micro-vessels – to meet the changing metabolic demand of the tissue. The competition between an ever decreasing tendency of luminal diameters and an increasing stimulus from the wall shear stress plays a key role in the adaptation of luminal diameters. However, it has been shown in previous studies that the adaptation dynamics based only on these two effects is unstable. In this work, we propose a minimal adaptation model of vessel luminal diameters, in which we take into account the effects of metabolic flow regulation in addition to wall shear stresses and the decreasing tendency of luminal diameters. In particular, we study the role, in the adaptation process, of fluctuations in capillary flow distribution which is an important means of metabolic flow regulation. The fluctuation in the flow of a capillary group is idealized as a switch between two states, i.e., an open-state and a close-state. Using this model, we show that the adaptation of blood vessel system driven by wall shear stress can be efficiently stabilized when the open time ratio responds sensitively to capillary flows. As micro-vessel rarefaction is observed in our simulations with a uniformly decreased open time ratio of capillary flows, our results point to a possible origin of micro-vessel rarefaction, which is believed to induce hypertension. PMID:23029014

Instabilities in wormlike micelle systems. From shear-banding to elastic turbulence.

PubMed

Fardin, M-A; Lerouge, S

2012-09-01

Shear-banding is ubiquitous in complex fluids. It is related to the organization of the flow into macroscopic bands bearing different viscosities and local shear rates and stacked along the velocity gradient direction. This flow-induced transition towards a heterogeneous flow state has been reported in a variety of systems, including wormlike micellar solutions, telechelic polymers, emulsions, clay suspensions, colloidal gels, star polymers, granular materials, or foams. In the past twenty years, shear-banding flows have been probed by various techniques, such as rheometry, velocimetry and flow birefringence. In wormlike micelle solutions, many of the data collected exhibit unexplained spatio-temporal fluctuations. Different candidates have been identified, the main ones being wall slip, interfacial instability between bands or bulk instability of one of the bands. In this review, we present experimental evidence for a purely elastic instability of the high shear rate band as the main origin for fluctuating shear-banding flows.

Analysis of two-equation turbulence models for recirculating flows

NASA Technical Reports Server (NTRS)

Thangam, S.

1991-01-01

The two-equation kappa-epsilon model is used to analyze turbulent separated flow past a backward-facing step. It is shown that if the model constraints are modified to be consistent with the accepted energy decay rate for isotropic turbulence, the dominant features of the flow field, namely the size of the separation bubble and the streamwise component of the mean velocity, can be accurately predicted. In addition, except in the vicinity of the step, very good predictions for the turbulent shear stress, the wall pressure, and the wall shear stress are obtained. The model is also shown to provide good predictions for the turbulence intensity in the region downstream of the reattachment point. Estimated long time growth rates for the turbulent kinetic energy and dissipation rate of homogeneous shear flow are utilized to develop an optimal set of constants for the two equation kappa-epsilon model. The physical implications of the model performance are also discussed.

Investigation of blood flow rheology using second-grade viscoelastic model (Phan-Thien-Tanner) within carotid artery.

PubMed

Ramiar, Abas; Larimi, Morsal Momenti; Ranjbar, Ali Akbar

2017-01-01

Hemodynamic factors, such as Wall Shear Stress (WSS), play a substantial role in arterial diseases. In the larger arteries, such as the carotid artery, interaction between the vessel wall and blood flow affects the distribution of hemodynamic factors. The fluid is considered to be non-Newtonian, whose flow is governed by the equation of a second-grade viscoelastic fluid and the effects of viscoelastic on blood flow in carotid artery is investigated. Pulsatile flow studies were carried out in a 3D model of carotid artery. The governing equations were solved using finite volume C++ based on open source code, OpenFOAM. To describe blood flow, conservation of mass and momentum, a constitutive relation of simplified Phan-Thien-Tanner (sPTT), and appropriate relations were used to explain shear thinning behavior. The first recirculation was observed at t = 0.2 s, in deceleration phase. In the acceleration phase from t = 0.3 s to t = 0.5 s, vortex and recirculation sizes in bulb regions in both ECA and ICA gradually increased. As is observed in the line graphs based on extracted data from ICA, at t = 0.2 s, τyy is the maximum amount of wall shear stress and τxy the minimum one. The maximum shear stress occurred in the inner side of the main branch (inner side of ICA and ECA) because the velocity of blood flow in the inner side of the bulb region was maximum due to the created recirculation zone in the opposite side in this area. The rheology of blood flow and shear stress in various important parts (the area that are in higher rates of WSS such as bifurcation region and the regions after bulb areas in both branches, Line1-4 in Fig. 7) were also analyzed. The investigation of velocity stream line, velocity profile and shear stress in various sections of carotid artery showed that the maximum shear stress occurred in acceleration phase and in the bifurcation region between ECA and ICA which is due to velocity gradients and changes in thinning behavior of blood and increasing strain rate in Newtonian stress part.

Brownian dynamics simulations of polyelectrolyte adsorption in shear flow with hydrodynamic interaction

NASA Astrophysics Data System (ADS)

Hoda, Nazish; Kumar, Satish

2007-12-01

The adsorption of single polyelectrolyte molecules in shear flow is studied using Brownian dynamics simulations with hydrodynamic interaction (HI). Simulations are performed with bead-rod and bead-spring chains, and electrostatic interactions are incorporated through a screened Coulombic potential with excluded volume accounted for by the repulsive part of a Lennard-Jones potential. A correction to the Rotne-Prager-Yamakawa tensor is derived that accounts for the presence of a planar wall. The simulations show that migration away from an uncharged wall, which is due to bead-wall HI, is enhanced by increases in the strength of flow and intrachain electrostatic repulsion, consistent with kinetic theory predictions. When the wall and polyelectrolyte are oppositely charged, chain behavior depends on the strength of electrostatic screening. For strong screening, chains get depleted from a region close to the wall and the thickness of this depletion layer scales as N1/3Wi2/3 at high Wi, where N is the chain length and Wi is the Weissenberg number. At intermediate screening, bead-wall electrostatic attraction competes with bead-wall HI, and it is found that there is a critical Weissenberg number for desorption which scales as N-1/2κ-3(lB∣σq∣)3/2, where κ is the inverse screening length, lB is the Bjerrum length, σ is the surface charge density, and q is the bead charge. When the screening is weak, adsorbed chains are observed to align in the vorticity direction at low shear rates due to the effects of repulsive intramolecular interactions. At higher shear rates, the chains align in the flow direction. The simulation method and results of this work are expected to be useful for a number of applications in biophysics and materials science in which polyelectrolyte adsorption plays a key role.

Simulation of blood flow using extended Boltzmann kinetic approach

NASA Astrophysics Data System (ADS)

Chen, Caixia; Chen, Hudong; Freed, David; Shock, Richard; Staroselsky, Ilya; Zhang, Raoyang; Ümit Coşkun, A.; Stone, Peter H.; Feldman, Charles L.

2006-03-01

Lattice Boltzmann (LB) simulations are conducted to obtain the detailed hydrodynamics in a variety of blood vessel setups, including a prototype stented channel and four human coronary artery geometries based on the images obtained from real patients. For a model of stented flow involving an S-shape stent, a pulsatile flow rate is applied as the inlet boundary condition, and the time- and space-dependent flow field is computed. The LB simulation is found to reproduce the analytical solutions for the velocity profiles and wall shear stress distributions for the pulsatile channel flow. For the coronary arteries, the distributions of wall shear stress, which is important for clinical diagnostic purposes, are in good agreement with the conventional CFD predictions.

Modeling of Wall-Bounded Complex Flows and Free Shear Flows

NASA Technical Reports Server (NTRS)

Shih, Tsan-Hsing; Zhu, Jiang; Lumley, John L.

1994-01-01

Various wall-bounded flows with complex geometries and free shear flows have been studied with a newly developed realizable Reynolds stress algebraic equation model. The model development is based on the invariant theory in continuum mechanics. This theory enables us to formulate a general constitutive relation for the Reynolds stresses. Pope was the first to introduce this kind of constitutive relation to turbulence modeling. In our study, realizability is imposed on the truncated constitutive relation to determine the coefficients so that, unlike the standard k-E eddy viscosity model, the present model will not produce negative normal stresses in any situations of rapid distortion. The calculations based on the present model have shown an encouraging success in modeling complex turbulent flows.

Effects of Renal Denervation on Renal Artery Function in Humans: Preliminary Study

PubMed Central

Doltra, Adelina; Hartmann, Arthur; Stawowy, Philipp; Goubergrits, Leonid; Kuehne, Titus; Wellnhofer, Ernst; Gebker, Rolf; Schneeweis, Christopher; Schnackenburg, Bernhard; Esler, Murray; Fleck, Eckart; Kelle, Sebastian

2016-01-01

Aim To study the effects of RD on renal artery wall function non-invasively using magnetic resonance. Methods and Results 32 patients undergoing RD were included. A 3.0 Tesla magnetic resonance of the renal arteries was performed before RD and after 6-month. We quantified the vessel sharpness of both renal arteries using a quantitative analysis tool (Soap-Bubble®). In 17 patients we assessed the maximal and minimal cross-sectional area of both arteries, peak velocity, mean flow, and renal artery distensibility. In a subset of patients wall shear stress was assessed with computational flow dynamics. Neither renal artery sharpness nor renal artery distensibility differed significantly. A significant increase in minimal and maximal areas (by 25.3%, p = 0.008, and 24.6%, p = 0.007, respectively), peak velocity (by 16.9%, p = 0.021), and mean flow (by 22.4%, p = 0.007) was observed after RD. Wall shear stress significantly decreased (by 25%, p = 0.029). These effects were observed in blood pressure responders and non-responders. Conclusions RD is not associated with adverse effects at renal artery level, and leads to an increase in cross-sectional areas, velocity and flow and a decrease in wall shear stress. PMID:27003912

Experimental and CFD flow studies in an intracranial aneurysm model with Newtonian and non-Newtonian fluids.

PubMed

Frolov, S V; Sindeev, S V; Liepsch, D; Balasso, A

2016-05-18

According to the clinical data, flow conditions play a major role in the genesis of intracranial aneurysms. The disorder of the flow structure is the cause of damage of the inner layer of the vessel wall, which leads to the development of cerebral aneurysms. Knowledge of the alteration of the flow field in the aneurysm region is important for treatment. The aim is to study quantitatively the flow structure in an patient-specific aneurysm model of the internal carotid artery using both experimental and computational fluid dynamics (CFD) methods with Newtonian and non-Newtonian fluids. A patient-specific geometry of aneurysm of the internal carotid artery was used. Patient data was segmented and smoothed to obtain geometrical model. An elastic true-to-scale silicone model was created with stereolithography. For initial investigation of the blood flow, the flow was visualized by adding particles into the silicone model. The precise flow velocity measurements were done using 1D Laser Doppler Anemometer with a spatial resolution of 50 μ m and a temporal resolution of 1 ms. The local velocity measurements were done at a distance of 4 mm to each other. A fluid with non-Newtonian properties was used in the experiment. The CFD simulations for unsteady-state problem were done using constructed hexahedral mesh for Newtonian and non-Newtonian fluids. Using 1D laser Doppler Anemometer the minimum velocity magnitude at the end of systole -0.01 m/s was obtained in the aneurysm dome while the maximum velocity 1 m/s was at the center of the outlet segment. On central cross section of the aneurysm the maximum velocity value is only 20% of the average inlet velocity. The average velocity on the cross-section is only 11% of the inlet axial velocity. Using the CFD simulation the wall shear stresses for Newtonian and non-Newtonian fluid at the end of systolic phase (t= 0.25 s) were computed. The wall shear stress varies from 3.52 mPa (minimum value) to 10.21 Pa (maximum value) for the Newtonian fluid. For the non-Newtonian fluid the wall shear stress minimum is 2.94 mPa; the maximum is 9.14 Pa. The lowest value of the wall shear stress for both fluids was obtained at the dome of the aneurysm while the highest wall shear stress was at the beginning of the outlet segment. The vortex in the aneurysm region is unstable during the cardiac cycle. The clockwise rotation of the streamlines at the inlet segment for Newtonian and non-Newtonian fluid is shown. The results of the present study are in agreement with the hemodynamics theory of aneurysm genesis. Low value of wall shear stress is observed at the aneurysm dome which can cause a rupture of an aneurysm.

Interaction between a normal shock wave and a turbulent boundary layer at high transonic speeds. Part 1: Pressure distribution. Part 2: Wall shear stress. Part 3: Simplified formulas for the prediction of surface pressures and skin friction

NASA Technical Reports Server (NTRS)

Adamson, T. C., Jr.; Liou, M. S.; Messiter, A. F.

1980-01-01

An asymptotic description is derived for the interaction between a shock wave and a turbulent boundary layer in transonic flow, for a particular limiting case. The dimensionless difference between the external flow velocity and critical sound speed is taken to be much smaller than one, but large in comparison with the dimensionless friction velocity. The basic results are derived for a flat plate, and corrections for longitudinal wall curvature and for flow in a circular pipe are also shown. Solutions are given for the wall pressure distribution and the shape of the shock wave. Solutions for the wall shear stress are obtained, and a criterion for incipient separation is derived. Simplified solutions for both the wall pressure and skin friction distributions in the interaction region are given. These results are presented in a form suitable for use in computer programs.

Pressure measurements in a rapidly sheared turbulent wall layer

NASA Astrophysics Data System (ADS)

Diwan, Sourabh; Morrison, Jonathan

2014-11-01

The aim of the present work is to improve understanding of the role of pressure fluctuations in the generation of coherent structures in wall-bounded turbulent flows, with particular regard to the rapid and slow source terms. The work is in part motivated by the recent numerical simulations of Sharma et al. (Phy. Fluids, 23, 2011), which showed the importance of pressure fluctuations (and their spatial gradients) in the dynamics of large-scale turbulent motions. Our experimental design consists of first generating a shearless boundary layer in a wind tunnel by passing a grid-generated turbulent flow over a moving floor whose speed is matched to the freestream velocity, and then shearing it rapidly by passing it over a stationary floor further downstream. Close to the leading edge of the stationary floor, the resulting flow is expected to satisfy the approximations of the Rapid Distortion Theory and therefore would be an ideal candidate for studying linear processes in wall turbulence. We carry out pressure measurements on the wall as well as within the flow - the former using surface mounted pressure transducers and the latter using a static pressure probe similar in design to that used by Tsuji et al. (J. Fluid. Mech. 585, 2007). We also present a comparison between the rapidly sheared flow and a more conventional boundary layer subjected to a turbulent free stream. We acknowledge the financial support from EPSRC (Grant No. EP/I037938).

Circulatory shear flow alters the viability and proliferation of circulating colon cancer cells

NASA Astrophysics Data System (ADS)

Fan, Rong; Emery, Travis; Zhang, Yongguo; Xia, Yuxuan; Sun, Jun; Wan, Jiandi

2016-06-01

During cancer metastasis, circulating tumor cells constantly experience hemodynamic shear stress in the circulation. Cellular responses to shear stress including cell viability and proliferation thus play critical roles in cancer metastasis. Here, we developed a microfluidic approach to establish a circulatory microenvironment and studied circulating human colon cancer HCT116 cells in response to a variety of magnitude of shear stress and circulating time. Our results showed that cell viability decreased with the increase of circulating time, but increased with the magnitude of wall shear stress. Proliferation of cells survived from circulation could be maintained when physiologically relevant wall shear stresses were applied. High wall shear stress (60.5 dyne/cm2), however, led to decreased cell proliferation at long circulating time (1 h). We further showed that the expression levels of β-catenin and c-myc, proliferation regulators, were significantly enhanced by increasing wall shear stress. The presented study provides a new insight to the roles of circulatory shear stress in cellular responses of circulating tumor cells in a physiologically relevant model, and thus will be of interest for the study of cancer cell mechanosensing and cancer metastasis.

Experimental Tests of Nonlocal Rheology in Dense Granular Flows

NASA Astrophysics Data System (ADS)

Tang, Zhu; Brzinski, Ted; Shearer, Michael; Daniels, Karen

Several nonlocal granular rheology models have been proposed to address shortcomings in local rheology models. One such model, developed by Kamrin & Koval, is based on extending a local Bagnold-type granular flow law by including a Laplacian term that accounts for the grain size and cooperative effects. We perform experiments to test this model in a quasi-2D annular shear geometry with a fixed outer wall and a rotating inner wall. We obtain the speed profile by particle tracking. We measure the inner wall torque, and calculate the pressure and shear stress on the outer wall using deformable laser-cut leaf springs. This allows us to calculate the relationship between the stress ratio μ and the inertial number I at different inner wall rotation speeds and packing fractions. The results are compared with nonlocal models.

The Flow in a Model Rotating-Wall Bioreactor.

NASA Astrophysics Data System (ADS)

Smith, Marc K.; Neitzel, G. Paul

1997-11-01

Aggregates of mammalian cells can be grown on artificial polymer constructs in a reactor vessel in order to produce high-quality tissue for medical applications. The growth and differentiation of these cells is greatly affected by the fluid flow and mass transfer within the bioreactor. The surface shear stress on the constructs is an especially important quantity of interest. Here, we consider a bioreactor in the form of two concentric, independently-rotating cylinders with the axis of rotation in a horizontal plane. We shall examine the flow around a model tissue construct in the form of a disk fixed in the flow produced by the rotating walls of the bioreactor. Using CFD techniques, we shall determine the flow field and the surface shear stress distribution on the construct as a function of the wall velocities, the Reynolds number of the flow, and the construct size and position. The results will be compared to the PIV measurements of this system reported by Brown & Neitzel(1997 Meeting of the APS/DFD.).

Investigation of Compressibility Effect for Aeropropulsive Shear Flows

NASA Technical Reports Server (NTRS)

Balasubramanyam, M. S.; Chen, C. P.

2005-01-01

Rocket Based Combined Cycle (RBCC) engines operate within a wide range of Mach numbers and altitudes. Fundamental fluid dynamic mechanisms involve complex choking, mass entrainment, stream mixing and wall interactions. The Propulsion Research Center at the University of Alabama in Huntsville is involved in an on- going experimental and numerical modeling study of non-axisymmetric ejector-based combined cycle propulsion systems. This paper attempts to address the modeling issues related to mixing, shear layer/wall interaction in a supersonic Strutjet/ejector flow field. Reynolds Averaged Navier-Stokes (RANS) solutions incorporating turbulence models are sought and compared to experimental measurements to characterize detailed flow dynamics. The effect of compressibility on fluids mixing and wall interactions were investigated using an existing CFD methodology. The compressibility correction to conventional incompressible two- equation models is found to be necessary for the supersonic mixing aspect of the ejector flows based on 2-D simulation results. 3-D strut-base flows involving flow separations were also investigated.

A Computational Model for Biomechanical Effects of Arterial Compliance Mismatch

PubMed Central

He, Fan; Hua, Lu; Gao, Li-jian

2015-01-01

Background. Compliance mismatch is a negative factor and it needs to be considered in arterial bypass grafting. Objective. A computational model was employed to investigate the effects of arterial compliance mismatch on blood flow, wall stress, and deformation. Methods. The unsteady blood flow was assumed to be laminar, Newtonian, viscous, and incompressible. The vessel wall was assumed to be linear elastic, isotropic, and incompressible. The fluid-wall interaction scheme was constructed using the finite element method. Results. The results show that there are identical wall shear stress waveforms, wall stress, and strain waveforms at different locations. The comparison of the results demonstrates that wall shear stresses and wall strains are higher while wall stresses are lower at the more compliant section. The differences promote the probability of intimal thickening at some locations. Conclusions. The model is effective and gives satisfactory results. It could be extended to all kinds of arteries with complicated geometrical and material factors. PMID:27019580

High shear microfluidics and its application in rheological measurement

NASA Astrophysics Data System (ADS)

Kang, Kai; Lee, L. James; Koelling, Kurt W.

2005-02-01

High shear rheology was explored experimentally in microchannels (150×150 μm). Two aqueous polymer solutions, polyethylene oxide (viscoelastic fluid) and hydroxyethyl cellulose (viscous fluid) were tested. Bagley correction was applied to remove the end effect. Wall slip was investigated with Mooney’s analysis. Shear rates as high as 106 s-1 were obtained in the pressure-driven microchannel flow, allowing a smooth extension of the low shear rheological data obtained from the conventional rheometers. At high shear rates, polymer degradation was observed for PEO solutions at a critical microchannel wall shear stress of 4.1×103 Pa. Stresses at the ends of the microchannel also contributed to PEO degradation significantly.

Mechanical Dissociation of Platelet Aggregates in Blood Stream

NASA Astrophysics Data System (ADS)

Hoore, Masoud; Fedosov, Dmitry A.; Gompper, Gerhard; Complex; Biological Fluids Group Team

2017-11-01

von Willebrand factor (VWF) and platelet aggregation is a key phenomenon in blood clotting. These aggregates form critically in high shear rates and dissolve reversibly in low shear rates. The emergence of a critical shear rate, beyond which aggregates form and below which they dissolve, has an interesting impact on aggregation in blood flow. As red blood cells (RBCs) migrate to the center of the vessel in blood flow, a RBC free layer (RBC-FL) is left close to the walls into which the platelets and VWFs are pushed back from the bulk flow. This margination process provides maximal VWF-platelet aggregation probability in the RBC-FL. Using mesoscale hydrodynamic simulations of aggregate dynamics in blood flow, it is shown that the aggregates form and grow in RBC-FL wherein shear rate is high for VWF stretching. By growing, the aggregates penetrate to the bulk flow and get under order of magnitude lower shear rates. Consequently, they dissolve and get back into the RBC-FL. This mechanical limitation for aggregates prohibits undesired thrombosis and vessel blockage by aggregates, while letting the VWFs and platelets to aggregate close to the walls where they are actually needed. The support by the DFG Research Unit FOR 1543 SHENC and CPU time Grant by the Julich Supercomputing Center are acknowledged.

High-order numerical simulations of pulsatile flow in a curved artery model

NASA Astrophysics Data System (ADS)

Cox, Christopher; Liang, Chunlei; Plesniak, Michael W.

2016-11-01

Cardiovascular flows are pulsatile, incompressible and occur in complex geometries with compliant walls. Together, these factors can produce an environment that can affect the progression of cardiovascular disease by altering wall shear stresses. Unstructured high-order CFD methods are well suited for capturing unsteady vortex-dominated viscous flows, and these methods provide high accuracy for similar cost as low-order methods. We use an in-house three-dimensional flux reconstruction Navier-Stokes solver to simulate secondary flows and vortical structures within a rigid 180-degree curved artery model under pulsatile flow of a Newtonian blood-analog fluid. Our simulations use a physiological flowrate waveform taken from the carotid artery. We are particularly interested in the dynamics during the deceleration phase of the waveform, where we observe the deformed-Dean, Dean, Lyne and Wall vortices. Our numerical results reveal the complex nature of these vortices both in space and time and their effect on overall wall shear stress. Numerical results agree with and complement experimental results obtained in our laboratory using particle image velocimetry. Supported by the GW Center for Biomimetics and Bioinspired Engineering.

Wall shear stress fixed points in cardiovascular fluid mechanics.

PubMed

Arzani, Amirhossein; Shadden, Shawn C

2018-05-17

Complex blood flow in large arteries creates rich wall shear stress (WSS) vectorial features. WSS acts as a link between blood flow dynamics and the biology of various cardiovascular diseases. WSS has been of great interest in a wide range of studies and has been the most popular measure to correlate blood flow to cardiovascular disease. Recent studies have emphasized different vectorial features of WSS. However, fixed points in the WSS vector field have not received much attention. A WSS fixed point is a point on the vessel wall where the WSS vector vanishes. In this article, WSS fixed points are classified and the aspects by which they could influence cardiovascular disease are reviewed. First, the connection between WSS fixed points and the flow topology away from the vessel wall is discussed. Second, the potential role of time-averaged WSS fixed points in biochemical mass transport is demonstrated using the recent concept of Lagrangian WSS structures. Finally, simple measures are proposed to quantify the exposure of the endothelial cells to WSS fixed points. Examples from various arterial flow applications are demonstrated. Copyright © 2018 Elsevier Ltd. All rights reserved.

Role of Wall Shear Stress in Cryptosporidium parvum Oocyst Attachment to Environmental Biofilms.

PubMed

Luo, Xia; Jedlicka, Sabrina S; Jellison, Kristen L

2017-12-15

This study investigated Cryptosporidium parvum oocyst deposition onto biofilms as a function of shear stress under laminar or turbulent flow. Annular rotating bioreactors were used to grow stabilized stream biofilms at shear stresses ranging from 0.038 to 0.46 Pa. These steady-state biofilms were then used to assess the impact of hydrodynamic conditions on C. parvum oocyst attachment. C. parvum deposition onto biofilms followed a pseudo-second-order model under both laminar (after a lag phase) and turbulent flows. The total number of oocysts attached to the biofilm at steady state decreased as the hydrodynamic wall shear stress increased. The oocyst deposition rate constant increased with shear stress but decreased at high shear, suggesting that increasing wall shear stress results in faster attachment of Cryptosporidium due to higher mass transport until the shear forces exceed a critical limit that prevents oocyst attachment. These data show that oocyst attachment in the short and long term are impacted differently by shear: higher shear (to a certain limit) may be associated with faster initial oocyst attachment, but lower shear is associated with greater numbers of oocysts attached at equilibrium. IMPORTANCE This research provides experimental evidence to demonstrate that shear stress plays a critical role in protozoan-pathogen transport and deposition in environmental waters. The data presented in this work expand scientific understanding of Cryptosporidium attachment and fate, which will further influence the development of timely and accurate sampling strategies, as well as advanced water treatment technologies, to target protozoan pathogens in surface waters that serve as municipal drinking water sources. Copyright © 2017 American Society for Microbiology.

GPU accelerated simulations of three-dimensional flow of power-law fluids in a driven cube

NASA Astrophysics Data System (ADS)

Jin, K.; Vanka, S. P.; Agarwal, R. K.; Thomas, B. G.

2017-01-01

Newtonian fluid flow in two- and three-dimensional cavities with a moving wall has been studied extensively in a number of previous works. However, relatively a fewer number of studies have considered the motion of non-Newtonian fluids such as shear thinning and shear thickening power law fluids. In this paper, we have simulated the three-dimensional, non-Newtonian flow of a power law fluid in a cubic cavity driven by shear from the top wall. We have used an in-house developed fractional step code, implemented on a Graphics Processor Unit. Three Reynolds numbers have been studied with power law index set to 0.5, 1.0 and 1.5. The flow patterns, viscosity distributions and velocity profiles are presented for Reynolds numbers of 100, 400 and 1000. All three Reynolds numbers are found to yield steady state flows. Tabulated values of velocity are given for the nine cases studied, including the Newtonian cases.

Assessment of fluctuating pressure gradient using acceleration spectra in near wall flows

NASA Astrophysics Data System (ADS)

Cadel, Daniel; Lowe, K. Todd

2015-11-01

Separation of contributions to the fluctuating acceleration from pressure gradient fluctuations and viscous shear fluctuations in the frequency domain is examined in a turbulent boundary layer. Past work leveraging turbulent accelerations for pressure gradient measurements has neglected the viscous shear term from the momentum equation--an invalid assumption in the case of near wall flows. The present study seeks to account for the influence of the viscous shear term and spectrally reject its contribution, which is thought to be concentrated at higher frequencies. Spectra of velocity and acceleration fluctuations in a flat plate, zero pressure gradient turbulent boundary layer at a momentum thickness Reynolds number of 7500 are measured using a spatially resolving three-component laser Doppler velocimeter. This canonical case data is applied for validation of the spectral approach for future application in more complex aerodynamic flows.

Analysis of wall shear stress around a competitive swimmer using 3D Navier-Stokes equations in CFD.

PubMed

Popa, C V; Zaidi, H; Arfaoui, A; Polidori, G; Taiar, R; Fohanno, S

2011-01-01

This paper deals with the flow dynamics around a competitive swimmer during underwater glide phases occurring at the start and at every turn. The influence of the head position, namely lifted up, aligned and lowered, on the wall shear stress and the static pressure distributions is analyzed. The problem is considered as 3D and in steady hydrodynamic state. Three velocities (1.4 m/s, 2.2 m/s and 3.1 m/s) that correspond to inter-regional, national and international swimming levels are studied. The flow around the swimmer is assumed turbulent. The Reynolds-averaged Navier-Stokes (RANS) equations are solved with the standard k-ω turbulent model by using the CFD (computational fluid dynamics) numerical method based on a volume control approach. Numerical simulations are carried out with the ANSYS FLUENT® CFD code. The results show that the wall shear stress increases with the velocity and consequently the drag force opposing the movement of the swimmer increases as well. Also, high wall shear stresses are observed in the areas where the body shape, globally rigid in form, presents complex surface geometries such as the head, shoulders, buttocks, heel and chest.

Predicting equilibrium states with Reynolds stress closures in channel flow and homogeneous shear flow

NASA Technical Reports Server (NTRS)

Abid, R.; Speziale, C. G.

1993-01-01

Turbulent channel flow and homogeneous shear flow have served as basic building block flows for the testing and calibration of Reynolds stress models. A direct theoretical connection is made between homogeneous shear flow in equilibrium and the log-layer of fully-developed turbulent channel flow. It is shown that if a second-order closure model is calibrated to yield good equilibrium values for homogeneous shear flow it will also yield good results for the log-layer of channel flow provided that the Rotta coefficient is not too far removed from one. Most of the commonly used second-order closure models introduce an ad hoc wall reflection term in order to mask deficient predictions for the log-layer of channel flow that arise either from an inaccurate calibration of homogeneous shear flow or from the use of a Rotta coefficient that is too large. Illustrative model calculations are presented to demonstrate this point which has important implications for turbulence modeling.

Predicting equilibrium states with Reynolds stress closures in channel flow and homogeneous shear flow

NASA Technical Reports Server (NTRS)

Abid, R.; Speziale, C. G.

1992-01-01

Turbulent channel flow and homogeneous shear flow have served as basic building block flows for the testing and calibration of Reynolds stress models. A direct theoretical connection is made between homogeneous shear flow in equilibrium and the log-layer of fully-developed turbulent channel flow. It is shown that if a second-order closure model is calibrated to yield good equilibrium values for homogeneous shear flow it will also yield good results for the log-layer of channel flow provided that the Rotta coefficient is not too far removed from one. Most of the commonly used second-order closure models introduce an ad hoc wall reflection term in order to mask deficient predictions for the log-layer of channel flow that arise either from an inaccurate calibration of homogeneous shear flow or from the use of a Rotta coefficient that is too large. Illustrative model calculations are presented to demonstrate this point which has important implications for turbulence modeling.

A three-dimensional spectral algorithm for simulations of transition and turbulence

NASA Technical Reports Server (NTRS)

Zang, T. A.; Hussaini, M. Y.

1985-01-01

A spectral algorithm for simulating three dimensional, incompressible, parallel shear flows is described. It applies to the channel, to the parallel boundary layer, and to other shear flows with one wall bounded and two periodic directions. Representative applications to the channel and to the heated boundary layer are presented.

Wall shear stress in intracranial aneurysms and adjacent arteries☆

PubMed Central

Wang, Fuyu; Xu, Bainan; Sun, Zhenghui; Wu, Chen; Zhang, Xiaojun

2013-01-01

Hemodynamic parameters play an important role in aneurysm formation and growth. However, it is difficult to directly observe a rapidly growing de novo aneurysm in a patient. To investigate possible associations between hemodynamic parameters and the formation and growth of intracranial aneurysms, the present study constructed a computational model of a case with an internal carotid artery aneurysm and an anterior communicating artery aneurysm, based on the CT angiography findings of a patient. To simulate the formation of the anterior communicating artery aneurysm and the growth of the internal carotid artery aneurysm, we then constructed a model that virtually removed the anterior communicating artery aneurysm, and a further two models that also progressively decreased the size of the internal carotid artery aneurysm. Computational simulations of the fluid dynamics of the four models were performed under pulsatile flow conditions, and wall shear stress was compared among the different models. In the three aneurysm growth models, increasing size of the aneurysm was associated with an increased area of low wall shear stress, a significant decrease in wall shear stress at the dome of the aneurysm, and a significant change in the wall shear stress of the parent artery. The wall shear stress of the anterior communicating artery remained low, and was significantly lower than the wall shear stress at the bifurcation of the internal carotid artery or the bifurcation of the middle cerebral artery. After formation of the anterior communicating artery aneurysm, the wall shear stress at the dome of the internal carotid artery aneurysm increased significantly, and the wall shear stress in the upstream arteries also changed significantly. These findings indicate that low wall shear stress may be associated with the initiation and growth of aneurysms, and that aneurysm formation and growth may influence hemodynamic parameters in the local and adjacent arteries. PMID:25206394

Structure of high and low shear-stress events in a turbulent boundary layer

NASA Astrophysics Data System (ADS)

Gomit, G.; de Kat, R.; Ganapathisubramani, B.

2018-01-01

Simultaneous particle image velocimetry (PIV) and wall-shear-stress sensor measurements were performed to study structures associated with shear-stress events in a flat plate turbulent boundary layer at a Reynolds number Reτ≈4000 . The PIV field of view covers 8 δ (where δ is the boundary layer thickness) along the streamwise direction and captures the entire boundary layer in the wall-normal direction. Simultaneously, wall-shear-stress measurements that capture the large-scale fluctuations were taken using a spanwise array of hot-film skin-friction sensors (spanning 2 δ ). Based on this combination of measurements, the organization of the conditional wall-normal and streamwise velocity fluctuations (u and v ) and of the Reynolds shear stress (-u v ) can be extracted. Conditional averages of the velocity field are computed by dividing the histogram of the large-scale wall-shear-stress fluctuations into four quartiles, each containing 25% of the occurrences. The conditional events corresponding to the extreme quartiles of the histogram (positive and negative) predominantly contribute to a change of velocity profile associated with the large structures and in the modulation of the small scales. A detailed examination of the Reynolds shear-stress contribution related to each of the four quartiles shows that the flow above a low wall-shear-stress event carries a larger amount of Reynolds shear stress than the other quartiles. The contribution of the small and large scales to this observation is discussed based on a scale decomposition of the velocity field.

Flow Enhancement due to Elastic Turbulence in Channel Flows of Shear Thinning Fluids

NASA Astrophysics Data System (ADS)

Bodiguel, Hugues; Beaumont, Julien; Machado, Anaïs; Martinie, Laetitia; Kellay, Hamid; Colin, Annie

2015-01-01

We explore the flow of highly shear thinning polymer solutions in straight geometry. The strong variations of the normal forces close to the wall give rise to an elastic instability. We evidence a periodic motion close the onset of the instability, which then evolves towards a turbulentlike flow at higher flow rates. Strikingly, we point out that this instability induces genuine drag reduction due to the homogenization of the viscosity profile by the turbulent flow.

Flow enhancement due to elastic turbulence in channel flows of shear thinning fluids.

PubMed

Bodiguel, Hugues; Beaumont, Julien; Machado, Anaïs; Martinie, Laetitia; Kellay, Hamid; Colin, Annie

2015-01-16

We explore the flow of highly shear thinning polymer solutions in straight geometry. The strong variations of the normal forces close to the wall give rise to an elastic instability. We evidence a periodic motion close the onset of the instability, which then evolves towards a turbulentlike flow at higher flow rates. Strikingly, we point out that this instability induces genuine drag reduction due to the homogenization of the viscosity profile by the turbulent flow.

Measurement of the Shear Lift Force on a Bubble in a Channel Flow

NASA Technical Reports Server (NTRS)

Nahra, Henry K.; Motil, Brian; Skor, Mark

2005-01-01

Two-phase flow systems play vital roles in the design of some current and anticipated space applications of two-phase systems which include: thermal management systems, transfer line flow in cryogenic storage, space nuclear power facilities, design and operation of thermal bus, life support systems, propulsion systems, In Situ Resource Utilization (ISRU), and space processes for pharmaceutical applications. The design of two-phase flow systems for space applications requires a clear knowledge of the behaviors of the dispersed phase (bubble), its interaction with the continuous phase (liquid) and its effect on heat and mass transfer processes, The need to understand the bubble generation process arises from the fact that for all space applications, the size and distribution of bubbles are extremely crucial for heat and mass transfer control. One important force in two-phase flow systems is the lift force on a bubble or particle in a liquid shear flow. The shear lift is usually overwhelmed by buoyancy in normal gravity, but it becomes an important force in reduced gravity. Since the liquid flow is usually sheared because of the confining wall, the trajectories of bubbles and particles injected into the liquid flow are affected by the shear lift in reduced gravity. A series of experiments are performed to investigate the lift force on a bubble in a liquid shear flow and its effect on the detachment of a bubble from a wall under low gravity conditions. Experiments are executed in a Poiseuille flow in a channel. An air-water system is used in these experiments that are performed in the 2.2 second drop tower. A bubble is injected into the shear flow from a small injector and the shear lift is measured while the bubble is held stationary relative to the fluid. The trajectory of the bubble prior, during and after its detachment from the injector is investigated. The measured shear lift force is calculated from the trajectory of the bubble at the detachment point. These values for the shear lift are then compared with the theoretical predictions from various published works on shear lift in the open literature, which include asymptotic solutions at low bubble Reynolds number, potential flow predictions and numerical studies that deal with intermediate bubble Reynolds numbers.

Streamline curvature in supersonic shear layers

NASA Technical Reports Server (NTRS)

Kibens, V.

1992-01-01

Results of an experimental investigation in which a curved shear layer was generated between supersonic flow from a rectangular converging/diverging nozzle and the freestream in a series of open channels with varying radii of curvature are reported. The shear layers exhibit unsteady large-scale activity at supersonic pressure ratios, indicating increased mixing efficiency. This effect contrasts with supersonic flow in a straight channel, for which no large-scale vortical structure development occurs. Curvature must exceed a minimum level before it begins to affect the dynamics of the supersonic shear layer appreciably. The curved channel flows are compared with reference flows consisting of a free jet, a straight channel, and wall jets without sidewalls on a flat and a curved plate.

On a turbulent wall model to predict hemolysis numerically in medical devices

NASA Astrophysics Data System (ADS)

Lee, Seunghun; Chang, Minwook; Kang, Seongwon; Hur, Nahmkeon; Kim, Wonjung

2017-11-01

Analyzing degradation of red blood cells is very important for medical devices with blood flows. The blood shear stress has been recognized as the most dominant factor for hemolysis in medical devices. Compared to laminar flows, turbulent flows have higher shear stress values in the regions near the wall. In case of predicting hemolysis numerically, this phenomenon can require a very fine mesh and large computational resources. In order to resolve this issue, the purpose of this study is to develop a turbulent wall model to predict the hemolysis more efficiently. In order to decrease the numerical error of hemolysis prediction in a coarse grid resolution, we divided the computational domain into two regions and applied different approaches to each region. In the near-wall region with a steep velocity gradient, an analytic approach using modeled velocity profile is applied to reduce a numerical error to allow a coarse grid resolution. We adopt the Van Driest law as a model for the mean velocity profile. In a region far from the wall, a regular numerical discretization is applied. The proposed turbulent wall model is evaluated for a few turbulent flows inside a cannula and centrifugal pumps. The results present that the proposed turbulent wall model for hemolysis improves the computational efficiency significantly for engineering applications. Corresponding author.

PIV Measurement of Wall Shear Stress and Flow Structures within an Intracranial Aneurysm Model

NASA Astrophysics Data System (ADS)

Chow, Ricky; Sparrow, Eph; Campbell, Gary; Divani, Afshin; Sheng, Jian

2012-11-01

The formation and rupture of an intracranial aneurysm (IA) is a debilitating and often lethal event. Geometric features of the aneurysm bulb and upstream artery, such as bulb size, bulb shape, and curvature of the artery, are two groups of factors that define the flow and stresses within an IA. Abnormal flow stresses are related to rupture. This presentation discusses the development of a quasi-3D PIV technique and its application in various glass models at Re = 275 and 550 to experimentally assess at a preliminary level the impact of geometry and flow rate. Some conclusions are to be drawn linking geometry of the flow domain to rupture risk. The extracted results also serve as the baseline case and as a precursor to a companion presentation by the authors discussing the impact of flow diverters, a new class of medical devices. The PIV experiments were performed in a fully index-matched flow facility, allowing for unobstructed observations over complex geometry. A reconstruction and analysis method was devised to obtain 3D mean wall stress distributions and flow fields. The quasi 3D measurements were reconstructed from orthogonal planes encompassing the entire glass model, spaced 0.4mm apart. Wall shear stresses were evaluated from the near-wall flow viscous stresses.

Haemodynamical stress in mouse aortic arch with atherosclerotic plaques: Preliminary study of plaque progression

PubMed Central

Assemat, P.; Siu, K.K.; Armitage, J.A.; Hokke, S.N.; Dart, A.; Chin-Dusting, J.; Hourigan, K.

2014-01-01

Atherosclerotic plaques develop at particular sites in the arterial tree, and this regional localisation depends largely on haemodynamic parameters (such as wall shear stress; WSS) as described in the literature. Plaque rupture can result in heart attack or stroke and hence understanding the development and vulnerability of atherosclerotic plaques is critically important. The purpose of this study is to characterise the haemodynamics of blood flow in the mouse aortic arch using numerical modelling. The geometries are digitalised from synchrotron imaging and realistic pulsatile blood flow is considered under rigid wall assumptions. Two cases are considered; arteries with and without plaque. Mice that are fed under fat diet present plaques in the aortic arch whose size is dependent on the number of weeks under the diet. The plaque distribution in the region is however relatively constant through the different samples. This result underlines the influence of the geometry and consequently of the wall shear stresses for plaque formation with plaques growing in region of relative low shear stresses. A discussion of the flow field in real geometry in the presence and absence of plaques is conducted. The presence of plaques was shown to alter the blood flow and hence WSS distribution, with regions of localised high WSS, mainly on the wall of the brachiocephalic artery where luminal narrowing is most pronounced. In addition, arch plaques are shown to induce recirculation in the blood flow, a phenomenon with potential influence on the progression of the plaques. The oscillatory shear index and the relative residence time have been calculated on the geometry with plaques to show the presence of this recirculation in the arch, an approach that may be useful for future studies on plaque progression. PMID:25349678

Measurement of the near-wall velocity profile for a nanofluid flow inside a microchannel

NASA Astrophysics Data System (ADS)

Kanjirakat, Anoop; Sadr, Reza

2015-11-01

Hydrodynamics and anomalous heat transfer enhancements have been reported in the past for colloidal suspensions of nano-sized particles dispersed in a fluid (nanofluids). However, such augmentations may manifest itself by study of fluid flow characteristics near in the wall region. Present experimental study reports near-wall velocity profile for nanofluids (silicon dioxide nanoparticles in water) measured inside a microchannel. An objective-based nano-Particle Image Velocimetry (nPIV) technique is used to measure fluid velocity within three visible depths, O(100nm), from the wall. The near-wall fluid velocity profile is estimated after implementing the required corrections for optical properties and effects caused by hindered Brownian motion, wall-particle interactions, and non-uniform exponential illumination on the measurement technique. The fluid velocities of nanofluids at each of the three visible depths are observed to be higher than that of the base fluid resulting in a higher shear rate in this region. The relative increase in shear rates for nanofluids is believed to be the result of the near-wall shear-induced particle migration along with the Brownian motion of the nanoparticles. This research is funded by NPRP grant # 08-574-2-239 from the Qatar National Research Fund (a member of Qatar Foundation).

Streaming potential of superhydrophobic microchannels.

PubMed

Park, Hung Mok; Kim, Damoa; Kim, Se Young

2017-03-01

For the purpose of gaining larger streaming potential, it has been suggested to employ superhydrophobic microchannels with a large velocity slip. There are two kinds of superhydrophobic surfaces, one having a smooth wall with a large Navier slip coefficient caused by the hydrophobicity of the wall material, and the other having a periodic array of no- shear slots of air pockets embedded in a nonslip wall. The electrokinetic flows over these two superhydrophobic surfaces are modelled using the Navier-Stokes equation and convection-diffusion equations of the ionic species. The Navier slip coefficient of the first kind surfaces and the no-shear slot ratio of the second kind surfaces are similar in the sense that the volumetric flow rate increases as these parameter values increase. However, although the streaming potential increases monotonically with respect to the Navier slip coefficient, it reaches a maximum and afterward decreases as the no-shear ratio increases. The results of the present investigation imply that the characterization of superhydrophobic surfaces employing only the measurement of volumetric flow rate against pressure drop is not appropriate and the fine structure of the superhydrophobic surfaces must be verified before predicting the streaming potential and electrokinetic flows accurately. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Numerical Study of Controlling Jet Flow and Noise using Pores on Nozzle Inner Wall

NASA Astrophysics Data System (ADS)

Lin, Jian; Shi, Zhixiao; Lai, Huanxin

2018-04-01

In this paper, the feasibility of controlling the subsonic jet flow and its noise using pores of blind holes added on the nozzle inner wall is explored numerically. These pores are intended to introduce disturbances to the shear layer so as to change the flow mixing. This passive strategy has not been attempted so far. A convergent nozzle with a cylindrical extension is selected as the baseline case. Three nozzles with pores on the inner wall are set up. Validations of the numerical settings are carried out, then the compressible turbulent jets at the exit Mach number M j = 0.6 in the four nozzles are calculated by large eddy simulations (LES), while the radiated sounds are predicted by the FW-H acoustic analogy. The results show that the blind holes have produced some effects on weakening the turbulence intensity in the shear layer. Comparison reveals that both temporal and spatial correlations of the turbulent fluctuations in the modified cases are suppressed to some extent. Meanwhile, the porous nozzles are shown to suppress the pairing of vortices and enhance the flow mixing, and therefore, the development of shear layer and the fragmentation of large scale vortices are accelerated.

Flow Instability and Wall Shear Stress Ocillation in Intracranial Aneurysms

NASA Astrophysics Data System (ADS)

Baek, Hyoungsu; Jayamaran, Mahesh; Richardson, Peter; Karniadakis, George

2009-11-01

We investigate the flow dynamics and oscillatory behavior of wall shear stress (WSS) vectors in intracranial aneurysms using high-order spectral/hp simulations. We analyze four patient- specific internal carotid arteries laden with aneurysms of different characteristics : a wide-necked saccular aneurysm, a hemisphere-shaped aneurysm, a narrower-necked saccular aneurysm, and a case with two adjacent saccular aneurysms. Simulations show that the pulsatile flow in aneurysms may be subject to a hydrodynamic instability during the decelerating systolic phase resulting in a high-frequency oscillation in the range of 30-50 Hz. When the aneurysmal flow becomes unstable, both the magnitude and the directions of WSS vectors fluctuate. In particular, the WSS vectors around the flow impingement region exhibit significant spatial and temporal changes in direction as well as in magnitude.

Wind turbine wakes in forest and neutral plane wall boundary layer large-eddy simulations

NASA Astrophysics Data System (ADS)

Schröttle, Josef; Piotrowski, Zbigniew; Gerz, Thomas; Englberger, Antonia; Dörnbrack, Andreas

2016-09-01

Wind turbine wake flow characteristics are studied in a strongly sheared and turbulent forest boundary layer and a neutral plane wall boundary layer flow. The reference simulations without wind turbine yield similar results as earlier large-eddy simulations by Shaw and Schumann (1992) and Porte-Agel et al. (2000). To use the fields from the homogeneous turbulent boundary layers on the fly as inflow fields for the wind turbine wake simulations, a new and efficient methodology was developed for the multiscale geophysical flow solver EULAG. With this method fully developed turbulent flow fields can be achieved upstream of the wind turbine which are independent of the wake flow. The large-eddy simulations reproduce known boundary-layer statistics as mean wind profile, momentum flux profile, and eddy dissipation rate of the plane wall and the forest boundary layer. The wake velocity deficit is more asymmetric above the forest and recovers faster downstream compared to the velocity deficit in the plane wall boundary layer. This is due to the inflection point in the mean streamwise velocity profile with corresponding turbulent coherent structures of high turbulence intensity in the strong shear flow above the forest.

Effects of sedimenting particles on the turbulence structure in a horizontal channel flow

NASA Astrophysics Data System (ADS)

Tay, Godwin F. K.; Kuhn, David C. S.; Tachie, Mark F.

2015-02-01

This work presents the results of experiments conducted in a horizontal channel to characterize low Reynolds number turbulent flows in the presence of small solid particles. The particle diameter relative to the integral length scale, dp/Λx, is approximately 0.02. Particles and fluid turbulence characteristics are measured for three average solid volume fractions of approximately ϕv = 2.0 × 10-4, 4.0 × 10-4, and 8.0 × 10-4 under conditions where the particle number density is evolving due to deposition. The results indicate that the mean slip between particles and the fluid is important only close to the wall. Away from the wall, the particles and unladen fluid mean velocities are similar. Differences between particles and the unladen fluid statistics are more pronounced in the wall-normal velocity fluctuations than the streamwise velocity fluctuations and Reynolds shear stress due to the stronger effect of the gravitational force in the wall-normal direction. The fluid turbulent intensities show no dependency on loading, but the peak Reynolds shear stress is significantly reduced. A quadrant decomposition of the Reynolds shear stress revealed a corresponding reduction in the ejections and sweeps for the laden flow in comparison with the unladen flow. Swirling strength and vorticity root-mean-square fluctuations decayed due to the damping effect of particles. The influence of particles on the turbulence structure was examined using two-point correlations of the velocity fluctuations and swirling strength, where it was demonstrated that the wall structures are attached eddies which are more extensive (much larger) in the particle-laden flow compared to the unladen flow.

Turbulent boundary layer on a convex, curved surface

NASA Technical Reports Server (NTRS)

Gillis, J. C.; Johnston, J. P.; Kays, W. M.; Moffat, R. J.

1980-01-01

The effects of strong convex curvature on boundary layer turbulence were investigated. The data gathered on the behavior of Reynolds stress suggested the formulation of a simple turbulence model. Three sets of data were taken on two separate facilities. Both rigs had flow from a flat surface, over a convex surface with 90 deg of turning, and then onto a flat recovery surface. The geometry was adjusted so that, for both rigs, the pressure gradient along the test surface was zero - thus avoiding any effects of streamwise acceleration on the wall layers. Results show that after a sudden introduction of curvature, the shear stress in the outer part of the boundary layer is sharply diminished and is even slightly negative near the edge. The wall shear also drops off quickly downstream. In contrast, when the surface suddenly becomes flat again, the wall shear and shear stress profiles recover very slowly towards flat wall conditions.

The Fluid Mechanics of a Wavy-Wall Bioreactor

NASA Astrophysics Data System (ADS)

Sucosky, Philippe; Bilgen, Bahar; Aleem, Alexander; Neitzel, Paul; Barabino, Gilda

2004-11-01

Bioreactors are devices used for the production of mammalian tissue in vitro. Although mixing has been shown to stimulate the growth of cartilage constructs, high shear-stress levels can damage the cells. In order to enhance mixing while minimizing shear, a wavy-wall bioreactor (WWB) featuring a sinusoidal internal profile has been designed. The turbulent hydrodynamic environment produced in this device is investigated experimentally using particle-image velocimetry. A model bioreactor made of acrylic and filled with an index-matching solution of zinc iodide is used to compensate for the refraction of light at the walls. The flow observed in different planes is shown to be periodic, spatially dependent, and dominated by mean-shear rather than Reynolds stresses in the vicinity of constructs. Finally, a comparison between the mean-shear stresses obtained in the WWB and in a standard spinner flask reveals similar stress levels near the construct walls.

DIRECT NUMERICAL SIMULATION OF TRANSITIONAL FLOW IN A STENOSED CAROTID BIFURCATION

PubMed Central

Lee, Seung E.; Lee, Sang-Wook; Fischer, Paul F.; Bassiouny, Hisham S.; Loth, Francis

2008-01-01

The blood flow dynamics of a stenosed, subject-specific, carotid bifurcation were numerically simulated using the spectral element method. Pulsatile inlet conditions were based on in vivo color Doppler ultrasound measurements of blood velocity. The results demonstrated the transitional or weakly turbulent state of the blood flow, which featured rapid velocity and pressure fluctuations in the post-stenotic region of the internal carotid artery during systole and laminar flow during diastole. High-frequency vortex shedding was greatest downstream of the stenosis during the deceleration phase of systole. Velocity fluctuations had a frequency within the audible range of 100–300 Hz. Instantaneous wall shear stress within the stenosis was relatively high during systole (~25-45 Pa) compared to that in a healthy carotid. In addition, high spatial gradients of wall shear stress were present due to flow separation on the inner wall. Oscillatory flow reversal and low pressure were observed distal to the stenosis in the internal carotid artery. This study predicts the complex flow field, the turbulence levels and the distribution of the biomechanical stresses present in vivo within a stenosed carotid artery. PMID:18656199

Bubble Motion through a Generalized Power-Law Fluid Flowing in a Vertical Tube

PubMed Central

Mukundakrishnan, Karthik; Eckmann, David M.; Ayyaswamy, P. S.

2009-01-01

Intravascular gas embolism may occur with decompression in space flight, as well as during cardiac and vascular surgery. Intravascular bubbles may be deposited into any end organ, such as the heart or the brain. Surface interactions between the bubble and the endothelial cells lining the vasculature result in serious impairment of blood flow and can lead to heart attack, stroke, or even death. To develop effective therapeutic strategies, there is a need for understanding the dynamics of bubble motion through blood and its interaction with the vessel wall through which it moves. Toward this goal, we numerically investigate the axisymmetric motion of a bubble moving through a vertical circular tube in a shear-thinning generalized power-law fluid, using a front-tracking method. The formulation is characterized by the inlet Reynolds number, capillary number, Weber number, and Froude number. The flow dynamics and the associated wall shear stresses are documented for a combination of two different inlet flow conditions (inlet Reynolds numbers) and three different effective bubble radii (ratio of the undeformed bubble radii to the tube radii). The results of the non-Newtonian model are then compared with that of the model assuming a Newtonian blood viscosity. Specifically, for an almost occluding bubble (effective bubble radius = 0.9), the wall shear stress and the bubble residence time are compared for both Newtonian and non-Newtonian cases. Results show that at low shear rates, for a given pressure gradient the residence time for a non-Newtonian flow is higher than that for a Newtonian flow. PMID:19426324

Measurement of surface shear stress vector beneath high-speed jet flow using liquid crystal coating

NASA Astrophysics Data System (ADS)

Wang, Cheng-Peng; Zhao, Ji-Song; Jiao, Yun; Cheng, Ke-Ming

2018-05-01

The shear-sensitive liquid crystal coating (SSLCC) technique is investigated in the high-speed jet flow of a micro-wind-tunnel. An approach to measure surface shear stress vector distribution using the SSLCC technique is established, where six synchronous cameras are used to record the coating color at different circumferential view angles. Spatial wall shear stress vector distributions on the test surface are obtained at different velocities. The results are encouraging and demonstrate the great potential of the SSLCC technique in high-speed wind-tunnel measurement.

Enhancement of wall jet transport properties

DOEpatents

Claunch, Scott D.; Farrington, Robert B.

1997-01-01

By enhancing the natural instabilities in the boundary layer and in the free shear layer of a wall jet, the boundary is minimized thereby increasing the transport of heat and mass. Enhancing the natural instabilities is accomplished by pulsing the flow of air that creates the wall jet. Such pulsing of the flow of air can be accomplished by sequentially occluding and opening a duct that confines and directs the flow of air, such as by rotating a disk on an axis transverse to the flow of air in the duct.

Enhancement of wall jet transport properties

DOEpatents

Claunch, S.D.; Farrington, R.B.

1997-02-04

By enhancing the natural instabilities in the boundary layer and in the free shear layer of a wall jet, the boundary is minimized thereby increasing the transport of heat and mass. Enhancing the natural instabilities is accomplished by pulsing the flow of air that creates the wall jet. Such pulsing of the flow of air can be accomplished by sequentially occluding and opening a duct that confines and directs the flow of air, such as by rotating a disk on an axis transverse to the flow of air in the duct. 17 figs.

Pulsatility Index as a Diagnostic Parameter of Reciprocating Wall Shear Stress Parameters in Physiological Pulsating Waveforms

PubMed Central

Avrahami, Idit; Kersh, Dikla

2016-01-01

Arterial wall shear stress (WSS) parameters are widely used for prediction of the initiation and development of atherosclerosis and arterial pathologies. Traditional clinical evaluation of arterial condition relies on correlations of WSS parameters with average flow rate (Q) and heart rate (HR) measurements. We show that for pulsating flow waveforms in a straight tube with flow reversals that lead to significant reciprocating WSS, the measurements of HR and Q are not sufficient for prediction of WSS parameters. Therefore, we suggest adding a third quantity—known as the pulsatility index (PI)—which is defined as the peak-to-peak flow rate amplitude normalized by Q. We examine several pulsating flow waveforms with and without flow reversals using a simulation of a Womersley model in a straight rigid tube and validate the simulations through experimental study using particle image velocimetry (PIV). The results indicate that clinically relevant WSS parameters such as the percentage of negative WSS (P[%]), oscillating shear index (OSI) and the ratio of minimum to maximum shear stress rates (min/max), are better predicted when the PI is used in conjunction with HR and Q. Therefore, we propose to use PI as an additional and essential diagnostic quantity for improved predictability of the reciprocating WSS. PMID:27893801

Variability of 4D flow parameters when subjected to changes in MRI acquisition parameters using a realistic thoracic aortic phantom.

PubMed

Montalba, Cristian; Urbina, Jesus; Sotelo, Julio; Andia, Marcelo E; Tejos, Cristian; Irarrazaval, Pablo; Hurtado, Daniel E; Valverde, Israel; Uribe, Sergio

2018-04-01

To assess the variability of peak flow, mean velocity, stroke volume, and wall shear stress measurements derived from 3D cine phase contrast (4D flow) sequences under different conditions of spatial and temporal resolutions. We performed controlled experiments using a thoracic aortic phantom. The phantom was connected to a pulsatile flow pump, which simulated nine physiological conditions. For each condition, 4D flow data were acquired with different spatial and temporal resolutions. The 2D cine phase contrast and 4D flow data with the highest available spatio-temporal resolution were considered as a reference for comparison purposes. When comparing 4D flow acquisitions (spatial and temporal resolution of 2.0 × 2.0 × 2.0 mm 3 and 40 ms, respectively) with 2D phase-contrast flow acquisitions, the underestimation of peak flow, mean velocity, and stroke volume were 10.5, 10 and 5%, respectively. However, the calculated wall shear stress showed an underestimation larger than 70% for the former acquisition, with respect to 4D flow, with spatial and temporal resolution of 1.0 × 1.0 × 1.0 mm 3 and 20 ms, respectively. Peak flow, mean velocity, and stroke volume from 4D flow data are more sensitive to changes of temporal than spatial resolution, as opposed to wall shear stress, which is more sensitive to changes in spatial resolution. Magn Reson Med 79:1882-1892, 2018. © 2017 International Society for Magnetic Resonance in Medicine. © 2017 International Society for Magnetic Resonance in Medicine.

Numerical study of wall shear stress-based descriptors in the human left coronary artery.

PubMed

Pinto, S I S; Campos, J B L M

2016-10-01

The present work is about the application of wall shear stress descriptors - time averaged wall shear stress (TAWSS), oscillating shear index (OSI) and relative residence time (RRT) - to the study of blood flow in the left coronary artery (LCA). These descriptors aid the prediction of disturbed flow conditions in the vessels and play a significant role in the detection of potential zones of atherosclerosis development. Hemodynamic descriptors data were obtained, numerically, through ANSYS® software, for the LCA of a patient-specific geometry and for a 3D idealized model. Comparing both cases, the results are coherent, in terms of location and magnitude. Low TAWSS, high OSI and high RRT values are observed in the bifurcation - potential zone of atherosclerosis appearance. The dissimilarities observed in the TAWSS values, considering blood as a Newtonian or non-Newtonian fluid, releases the importance of the correct blood rheologic caracterization. Moreover, for a higher Reynolds number, the TAWSS values decrease in the bifurcation and along the LAD branch, increasing the probability of plaques deposition. Furthermore, for a stenotic LCA model, very low TAWSS and high RRT values in front and behind the stenosis are observed, indicating the probable extension, in the flow direction, of the lesion.

Effects of vessel compliance on flow pattern in porcine epicardial right coronary arterial tree.

PubMed

Huo, Yunlong; Choy, Jenny Susana; Svendsen, Mark; Sinha, Anjan Kumar; Kassab, Ghassan S

2009-03-26

The compliance of the vessel wall affects hemodynamic parameters which may alter the permeability of the vessel wall. Based on experimental measurements, the present study established a finite element (FE) model in the proximal elastic vessel segments of epicardial right coronary arterial (RCA) tree obtained from computed tomography. The motion of elastic vessel wall was measured by an impedance catheter and the inlet boundary condition was measured by an ultrasound flow probe. The Galerkin FE method was used to solve the Navier-Stokes and Continuity equations, where the convective term in the Navier-Stokes equation was changed in the arbitrary Lagrangian-Eulerian (ALE) framework to incorporate the motion due to vessel compliance. Various hemodynamic parameters (e.g., wall shear stress-WSS, WSS spatial gradient-WSSG, oscillatory shear index-OSI) were analyzed in the model. The motion due to vessel compliance affects the time-averaged WSSG more strongly than WSS at bifurcations. The decrease of WSSG at flow divider in elastic bifurcations, as compared to rigid bifurcations, implies that the vessel compliance decreases the permeability of vessel wall and may be atheroprotective. The model can be used to predict coronary flow pattern in subject-specific anatomy as determined by noninvasive imaging.

A comparative CFD study on the hemodynamics of flow through an idealized symmetric and asymmetric stenosed arteries

NASA Astrophysics Data System (ADS)

Prashantha, B.; Anish, S.

2017-04-01

The aim of the present study is to numerically evaluate the hemodynamic factors which affect the formation of atherosclerosis and plaque rupture in the human artery. An increase of atherosclerosis in the artery causes geometry changes, which results in hemodynamic changes such as flow separation, reattachment and adhesion of new cells (chemotactic) in the artery. Hence, geometry plays an important role in the determining the nature of hemodynamic patterns. Influence of stenosis in the non-bifurcating artery, under pulsatile flow condition has been studied on an idealized geometry. Analysis of flow through symmetric and asymmetric stenosis in the artery revealed the significance of oscillating shear index (OSI), flow separation, low wall shear stress (WSS) zones and secondary flow patterns on plaque formation. The observed characteristic of flow in the post-stenotic region highlight the importance of plaque eccentricity on the formation of secondary stenosis on the arterial wall.

Impact of Wall Shear Stress and Pressure Variation on the Stability of Atherosclerotic Plaque

NASA Astrophysics Data System (ADS)

Taviani, V.; Li, Z. Y.; Sutcliffe, M.; Gillard, J.

Rupture of vulnerable atheromatous plaque in the carotid and coronary arteries often leads to stroke and heart attack respectively. The mechanism of blood flow and plaque rupture in stenotic arteries is still not fully understood. A three dimensional rigid wall model was solved under steady and unsteady conditions assuming a time-varying inlet velocity profile to investigate the relative importance of axial forces and pressure drops in arteries with asymmetric stenosis. Flow-structure interactions were investigated for the same geometry and the results were compared with those retrieved with the corresponding one dimensional models. The Navier-Stokes equations were used as the governing equations for the fluid. The tube wall was assumed linearly elastic, homogeneous isotropic. The analysis showed that wall shear stress is small (less than 3.5%) with respect to pressure drop throughout the cycle even for severe stenosis. On the contrary, the three dimensional behavior of velocity, pressure and wall shear stress is in general very different from that predicted by one dimensional models. This suggests that the primary source of mistakes in one dimensional studies comes from neglecting the three dimensional geometry of the plaque. Neglecting axial forces only involves minor errors.

Effect of TurboSwirl Structure on an Uphill Teeming Ingot Casting Process

NASA Astrophysics Data System (ADS)

Bai, Haitong; Ersson, Mikael; Jönsson, Pär

2015-12-01

To produce high-quality ingot cast steel with a better surface quality, it would be beneficial for the uphill teeming process if a much more stable flow pattern could be achieved in the runners. Several techniques have been utilized in the industry to try to obtain a stable flow of liquid steel, such as a swirling flow. Some research has indicated that a swirl blade inserted in the horizontal and vertical runners, or some other additional devices and physics could generate a swirling flow in order to give a lower hump height, avoid mold flux entrapment, and improve the quality of the ingot products, and a new swirling flow generation component, TurboSwirl, was introduced to improve the flow pattern. It has recently been demonstrated that the TurboSwirl method can effectively reduce the risk of mold flux entrapment, lower the maximum wall shear stress, and decrease velocity fluctuations. The TurboSwirl is built at the elbow of the runners as a connection between the horizontal and vertical runners. It is located near the mold and it generates a tangential flow that can be used with a divergent nozzle in order to decrease the axial velocity of the vertical flow into the mold. This stabilizes flow before the fluid enters the mold. However, high wall shear stresses develop at the walls due to the fierce rotation in the TurboSwirl. In order to achieve a calmer flow and to protect the refractory wall, some structural improvements have been made. It was found that by changing the flaring angle of the divergent nozzle, it was possible to lower the axial velocity and wall shear stress. Moreover, when the vertical runner and the divergent nozzle were not placed at the center of the TurboSwirl, quite different flow patterns could be obtained to meet to different requirements. In addition, the swirl numbers of all the cases mentioned above were calculated to ensure that the swirling flow was strong enough to generate a swirling flow of the liquid steel in the TurboSwirl.

Brownian dynamics of wall tethered polymers in shear flow

NASA Astrophysics Data System (ADS)

Lin, Tiras Y.; Saadat, Amir; Kushwaha, Amit; Shaqfeh, Eric S. G.

2017-11-01

The dynamics of a wall tethered polymer in shear flow is studied using Brownian dynamics. Simulations are performed with bead-spring chains, and the effect of hydrodynamic interactions (HI) is incorporated through Blake's tensor with a finite size bead correction. We characterize the configuration of the polymer as a function of the Weissenberg number by investigating the regions the polymer explores in both the flow-gradient and flow-vorticity planes. The fractional extension in the flow direction, the width in the vorticity direction, and the thickness in the gradient direction are reported as well, and these quantities are found to compare favorably with the experimental data of the literature. The cyclic motion of the polymer is demonstrated through analysis of the mean velocity field of the end bead. We characterize the collision process of each bead with the wall as a Poisson process and extract an average wall collision rate, which in general varies along the backbone of the chain. The inclusion of HI with the wall for a tethered polymer is found to reduce the average wall collision rate. We anticipate that results from this work will be directly applicable to, e.g., the design of polymer brushes or the use of DNA for making nanowires in molecular electronics. T.Y.L. is supported by the Department of Defense (DoD) through the National Defense Science & Engineering Graduate Fellowship (NDSEG) Program.

Pressure and wall shear stress in blood hammer - Analytical theory.

PubMed

Mei, Chiang C; Jing, Haixiao

2016-10-01

We describe an analytical theory of blood hammer in a long and stiffened artery due to sudden blockage. Based on the model of a viscous fluid in laminar flow, we derive explicit expressions of oscillatory pressure and wall shear stress. To examine the effects on local plaque formation we also allow the blood vessel radius to be slightly nonuniform. Without resorting to discrete computation, the asymptotic method of multiple scales is utilized to deal with the sharp contrast of time scales. The effects of plaque and blocking time on blood pressure and wall shear stress are studied. The theory is validated by comparison with existing water hammer experiments. Copyright © 2016. Published by Elsevier Inc.

Swirling flow in bileaflet mechanical heart valve

NASA Astrophysics Data System (ADS)

Gataulin, Yakov A.; Khorobrov, Svyatoslav V.; Yukhnev, Andrey D.

2018-05-01

Bileaflet mechanical valves are most commonly used for heart valve replacement. Nowadays swirling blood flow is registered in different parts of the cardiovascular system: left ventricle, aorta, arteries and veins. In present contribution for the first time the physiological swirling flow inlet conditions are used for numerical simulation of aortic bileaflet mechanical heart valve hemodynamics. Steady 3-dimensional continuity and RANS equations are employed to describe blood motion. The Menter SST model is used to simulate turbulence effects. Boundary conditions are corresponded to systolic peak flow. The domain was discretized into hybrid tetrahedral and hexahedral mesh with an emphasis on wall boundary layer. A system of equations was solved in Ansys Fluent finite-volume package. Noticeable changes in the flow structure caused by inlet swirl are shown. The swirling flow interaction with the valve leaflets is analyzed. A central orifice jet changes its cross-section shape, which leads to redistribution of wall shear stress on the leaflets. Transvalvular pressure gradient and area-averaged leaflet wall shear stress increase. Physiological swirl intensity noticeably reduces downstream of the valve.

On the dynamics of the flow in the vicinity of micro-scale coatings composed by organized elements

NASA Astrophysics Data System (ADS)

Doosttalab, Ali; Bocanegra Evans, Humberto; Gorumlu, Serdar; Aksak, Burak; Chamorro, Leonardo P.; Castillo, Luciano

2017-11-01

A set of high-resolution PIV experiments were carried out in a refractive index-matched facility under zero pressure gradient turbulent boundary layer to investigate the flow dynamics around two customized coatings composed of uniformly distributed fibers of different geometry. The two type of fibers shared a cylindrical shape and height y+ < 1 however, one of those had diverging tip similar to that of a shark skin. Results evidence an inter-layer acting between the viscous-dominated flow within the pillars canopy (where Re 1) and the inertia dominated flow in the boundary layer. Using averaged 2D N-S equations, it is possible to show that the inter-layer wall shear stress is τoiw+ = [∂U+/∂y+ - < uv+ > ] - [Pw+h+(y+/h+ - 1) + ] , with first term in the RHS representing the wall shear stress and the second term indicating the inter-layer form drag. A wall-normal Reynolds stress exist which depends on the pressure difference across the boundary layer and at the wall, = +( - < P >) / ρ . This reveals a basic mechanism where the flow is modulated by unsteady blowing and suction at the interface.

Dynamical eigenfunction decomposition of turbulent channel flow

NASA Technical Reports Server (NTRS)

Ball, K. S.; Sirovich, L.; Keefe, L. R.

1991-01-01

The results of an analysis of low-Reynolds-number turbulent channel flow based on the Karhunen-Loeve (K-L) expansion are presented. The turbulent flow field is generated by a direct numerical simulation of the Navier-Stokes equations at a Reynolds number Re(tau) = 80 (based on the wall shear velocity and channel half-width). The K-L procedure is then applied to determine the eigenvalues and eigenfunctions for this flow. The random coefficients of the K-L expansion are subsequently found by projecting the numerical flow field onto these eigenfunctions. The resulting expansion captures 90 percent of the turbulent energy with significantly fewer modes than the original trigonometric expansion. The eigenfunctions, which appear either as rolls or shearing motions, possess viscous boundary layers at the walls and are much richer in harmonics than the original basis functions.

Turbulent shear layers in confining channels

NASA Astrophysics Data System (ADS)

Benham, Graham P.; Castrejon-Pita, Alfonso A.; Hewitt, Ian J.; Please, Colin P.; Style, Rob W.; Bird, Paul A. D.

2018-06-01

We present a simple model for the development of shear layers between parallel flows in confining channels. Such flows are important across a wide range of topics from diffusers, nozzles and ducts to urban air flow and geophysical fluid dynamics. The model approximates the flow in the shear layer as a linear profile separating uniform-velocity streams. Both the channel geometry and wall drag affect the development of the flow. The model shows good agreement with both particle image velocimetry experiments and computational turbulence modelling. The simplicity and low computational cost of the model allows it to be used for benchmark predictions and design purposes, which we demonstrate by investigating optimal pressure recovery in diffusers with non-uniform inflow.

Transitional Flow in an Arteriovenous Fistula: Effect of Wall Distensibility

NASA Astrophysics Data System (ADS)

McGah, Patrick; Leotta, Daniel; Beach, Kirk; Aliseda, Alberto

2012-11-01

Arteriovenous fistulae are created surgically to provide adequate access for dialysis in patients with end-stage renal disease. Transitional flow and the subsequent pressure and shear stress fluctuations are thought to be causative in the fistula failure. Since 50% of fistulae require surgical intervention before year one, understanding the altered hemodynamic stresses is an important step toward improving clinical outcomes. We perform numerical simulations of a patient-specific model of a functioning fistula reconstructed from 3D ultrasound scans. Rigid wall simulations and fluid-structure interaction simulations using an in-house finite element solver for the wall deformations were performed and compared. In both the rigid and distensible wall cases, transitional flow is computed in fistula as evidenced by aperiodic high frequency velocity and pressure fluctuations. The spectrum of the fluctuations is much more narrow-banded in the distensible case, however, suggesting a partial stabilizing effect by the vessel elasticity. As a result, the distensible wall simulations predict shear stresses that are systematically 10-30% lower than the rigid cases. We propose a possible mechanism for stabilization involving the phase lag in the fluid work needed to deform the vessel wall. Support from an NIDDK R21 - DK08-1823.

A microfabricated microfluidic bioMEMS device to model human brain aneurisms: the aneurysm-on-a-chip

NASA Astrophysics Data System (ADS)

Reece, Lisa M.; Khor, Jian Wei; Thakur, Raviraj; Amin, Ahmed; Wereley, Steven T.; Leary, James F.

2015-03-01

Aneurysms are pockets of blood that collect outside blood vessel walls forming dilatations and leaving arterial walls very prone to rupture. There is little information concerning the causes of intracranial aneurysm formation, growth, and rupture. Current treatments include: (1) clipping, and (2) coil embolization, including stent-assisted coiling. Further, the evolution of any aneurysm is assumed to be caused by the remodeling of the affected blood vessel's material constituents (tunica intima, tunica media, or tunica adventitia). Velocity, pressure, and wall shear stresses aid in the disease development of aneurysmal growth, while the shear force mechanisms effecting wound closure are elusive. To study aneurysm pathogenesis, a lab-on-a-chip device is the key to discovering the underlying mechanisms of these lesions. A two-dimensional microfluidic model, the Aneurysm-on-a-Chip™ (AOC), was the logical answer to study particle flow within an aneurysm "sac". The AOC apparatus can track particles/cells when it is coupled to particle image velocimetry software (PIV) package. The AOC fluid flow was visualized using standard microscopy techniques with commercial microparticles and human aortic smooth muscle cells (HASMC). Images were taken during fluid flow experiments and PIV was utilized to monitor the flow of particles within the "sac" region, as well as particles entering and exiting the device. Quiver plots were generated from fluid flow experiments using standard 7 μm latex particles and fixed HASMC in PBS. PIV analysis shows that the particles flowed nicely from input to output. Wall shear stress provided evidence that there was some back flow at the edges of the "sac" - an indicator of aneurysm development in human patients.

Computational solution of the velocity and wall shear stress distribution inside a left carotid artery under pulsatile flow conditions

NASA Astrophysics Data System (ADS)

Arslan, Nurullah; Turmuş, Hakan

2014-08-01

Stroke is still one of the leading causes for death after heart diseases and cancer in all over the world. Strokes happen because an artery that carries blood uphill from the heart to the head is clogged. Most of the time, as with heart attacks, the problem is atherosclerosis, hardening of the arteries, calcified buildup of fatty deposits on the vessel wall. In this study, the fluid dynamic simulations were done in a left carotid bifurcation under the pulsatile flow conditions computationally. Pulsatile flow waveform is given in the paper. In vivo geometry and boundary conditions were obtained from a patient who has stenosis located at external carotid artery (ECA) and internal carotid artery (ICA) of his common carotid artery (CCA). The location of critical flow fields such as low wall shear stress (WSS), stagnation regions and separation regions were detected near the highly stenosed region and at branching region.

Wall shear stress estimation in the aorta: Impact of wall motion, spatiotemporal resolution, and phase noise.

PubMed

Zimmermann, Judith; Demedts, Daniel; Mirzaee, Hanieh; Ewert, Peter; Stern, Heiko; Meierhofer, Christian; Menze, Bjoern; Hennemuth, Anja

2018-04-01

Wall shear stress (WSS) presents an important parameter for assessing blood flow characteristics and evaluating flow-mediated lesions in the aorta. To investigate the robustness of WSS and oscillatory shear index (OSI) estimation based on 4D flow MRI against vessel wall motion, spatiotemporal resolution, and velocity encoding (VENC). Simulated and prospective. Synthetic 4D flow MRI data of the aorta, simulated using the Lattice-Boltzmann method; in vivo 4D flow MRI data of the aorta from healthy volunteers (n = 11) and patients with congenital heart defects (n = 17). 1.5T; 4D flow MRI with PEAK-GRAPPA acceleration and prospective electrocardiogram triggering. Predicated upon 3D cubic B-splines interpolation of the image velocity field, WSS was estimated in mid-systole, early-diastole, and late-diastole and OSI was derived. We assessed the impact of spatiotemporal resolution and phase noise, and compared results based on tracked-using deformable registration-and static vessel wall location. Bland-Altman analysis to assess WSS/OSI differences; Hausdorff distance (HD) to assess wall motion; and Pearson's correlation coefficient (PCC) to assess correlation of HD with WSS. Synthetic data results show systematic over-/underestimation of WSS when different spatial resolution (mean ± 1.96 SD up to -0.24 ± 0.40 N/m 2 and 0.5 ± 1.38 N/m 2 for 8-fold and 27-fold voxel size, respectively) and VENC-depending phase noise (mean ± 1.96 SD up to 0.31 ± 0.12 N/m 2 and 0.94 ± 0.28 N/m 2 for 2-fold and 4-fold VENC increase, respectively) are given. Neglecting wall motion when defining the vessel wall perturbs WSS estimates to a considerable extent (1.96 SD up to 1.21 N/m 2 ) without systematic over-/underestimation (Bland-Altman mean range -0.06 to 0.05). In addition to sufficient spatial resolution and velocity to noise ratio, accurate tracking of the vessel wall is essential for reliable image-based WSS estimation and should not be neglected if wall motion is present. 2 Technical Efficacy: Stage 2 J. Magn. Reson. Imaging 2018. © 2018 International Society for Magnetic Resonance in Medicine.

Coherent structures in wall-bounded turbulence

NASA Astrophysics Data System (ADS)

Jiménez, Javier

2018-05-01

This article discusses the description of wall-bounded turbulence as a deterministic high-dimensional dynamical system of interacting coherent structures, defined as eddies with enough internal dynamics to behave relatively autonomously from any remaining incoherent part of the flow. The guiding principle is that randomness is not a property, but a methodological choice of what to ignore in the flow, and that a complete understanding of turbulence, including the possibility of control, requires that it be kept to a minimum. After briefly reviewing the underlying low-order statistics of flows at moderate Reynolds numbers, the article examines what two-point statistics imply for the decomposition of the flow into individual eddies. Intense eddies are examined next, including their temporal evolution, and shown to satisfy many of the properties required for coherence. In particular, it is shown that coherent structures larger than the Corrsin scale are a natural consequence of the shear. In wall-bounded turbulence, they can be classified into coherent dispersive waves and transient bursts. The former are found in the viscous layer near the wall and as very-large structures spanning the boundary layer thickness. Although they are shear-driven, these waves have enough internal structure to maintain a uniform advection velocity. Conversely, bursts exist at all scales, are characteristic of the logarithmic layer, and interact almost linearly with the shear. While the waves require a wall to determine their length scale, the bursts are essentially independent from it. The article concludes with a brief review of our present theoretical understanding of turbulent structures, and with a list of open problems and future perspectives.

Reynolds number invariance of the structure inclination angle in wall turbulence.

PubMed

Marusic, Ivan; Heuer, Weston D C

2007-09-14

Cross correlations of the fluctuating wall-shear stress and the streamwise velocity in the logarithmic region of turbulent boundary layers are reported over 3 orders of magnitude change in Reynolds number. These results are obtained using hot-film and hot-wire anemometry in a wind tunnel facility, and sonic anemometers and a purpose-built wall-shear stress sensor in the near-neutral atmospheric surface layer on the salt flats of Utah's western desert. The direct measurement of fluctuating wall-shear stress in the atmospheric surface layer has not been available before. Structure inclination angles are inferred from the cross correlation results and are found to be invariant over the large range of Reynolds number. The findings justify the prior use of low Reynolds number experiments for obtaining structure angles for near-wall models in the large-eddy simulation of atmospheric surface layer flows.

Fluid Structure Interaction Analysis on Sidewall Aneurysm Models

NASA Astrophysics Data System (ADS)

Hao, Qing

2016-11-01

Wall shear stress is considered as an important factor for cerebral aneurysm growth and rupture. The objective of present study is to evaluate wall shear stress in aneurysm sac and neck by a fluid-structure-interaction (FSI) model, which was developed and validated against the particle image velocimetry (PIV) data. In this FSI model, the flow characteristics in a straight tube with different asymmetric aneurysm sizes over a range of Reynolds numbers from 200 to 1600 were investigated. The FSI results agreed well with PIV data. It was found that at steady flow conditions, when Reynolds number above 700, one large recirculating vortex would be formed, occupying the entire aneurysm sac. The center of the vortex is located at region near to the distal neck. A pair of counter rotating vortices would however be formed at Reynolds number below 700. Wall shear stresses reached highest level at the distal neck of the aneurysmal sac. The vortex strength, in general, is stronger at higher Reynolds number. Fluid Structure Interaction Analysis on Sidewall Aneurysm Models.

Measurements of wall shear stress in a planar turbulent Couette flow with porous walls

NASA Astrophysics Data System (ADS)

Beuther, Paul

2013-11-01

Measurements of drag on a moving web in a multi-span festoon show a stronger than expected dependency on the porosity of the web. The experiments suggest a wall shear stress 3-4 times larger than non-porous webs or historical Couette flow data for solid walls. Previous DNS studies by Jimenez et al. (JFM Vol 442) of boundary layers with passive porous surfaces predict a much smaller increase in wall shear stress for a porous wall of only 40%. Other DNS studies by Quadrio et al. (JFM Vol 576) of porous walls with periodic transpiration do show a large increase in drag under certain periodic conditions of modest amplitude. Although those results are aligned in magnitude with this study, the exact reason for the observed high drag for porous webs in this present study is not understood because there was no external disturbance applied to the web. It can be hypothesized that natural flutter of the web results in a similar mechanism shown in the periodic DNS study, but when the natural flutter was reduced by increasing web tension, there was only a small decrease of the drag. A key difference in this study is that because of the multiple parallel spans in a festoon, any transpiration in one layer must act in the opposite manner on the adjacent span.

Characterization of the secondary flow in hexagonal ducts

NASA Astrophysics Data System (ADS)

Marin, O.; Vinuesa, R.; Obabko, A. V.; Schlatter, P.

2016-12-01

In this work we report the results of DNSs and LESs of the turbulent flow through hexagonal ducts at friction Reynolds numbers based on centerplane wall shear and duct half-height Reτ,c ≃ 180, 360, and 550. The evolution of the Fanning friction factor f with Re is in very good agreement with experimental measurements. A significant disagreement between the DNS and previous RANS simulations was found in the prediction of the in-plane velocity, and is explained through the inability of the RANS model to properly reproduce the secondary flow present in the hexagon. The kinetic energy of the secondary flow integrated over the cross-sectional area yz decreases with Re in the hexagon, whereas it remains constant with Re in square ducts at comparable Reynolds numbers. Close connection between the values of Reynolds stress u w ¯ on the horizontal wall close to the corner and the interaction of bursting events between the horizontal and inclined walls is found. This interaction leads to the formation of the secondary flow, and is less frequent in the hexagon as Re increases due to the 120∘ aperture of its vertex, whereas in the square duct the 90∘ corner leads to the same level of interaction with increasing Re. Analysis of turbulence statistics at the centerplane and the azimuthal variance of the mean flow and the fluctuations shows a close connection between hexagonal ducts and pipe flows, since the hexagon exhibits near-axisymmetric conditions up to a distance of around 0.15DH measured from its center. Spanwise distributions of wall-shear stress show that in square ducts the 90∘ corner sets the location of a high-speed streak at a distance zv+≃50 from it, whereas in hexagons the 120∘ aperture leads to a shorter distance of zv+≃38 . At these locations the root mean square of the wall-shear stresses exhibits an inflection point, which further shows the connections between the near-wall structures and the large-scale motions in the outer flow.

Characterization of the secondary flow in hexagonal ducts

DOE PAGES

Marin, O.; Vinuesa, R.; Obabko, A. V.; ...

2016-12-06

In this work we report the results of DNSs and LESs of the turbulent flow through hexagonal ducts at friction Reynolds numbers based on centerplane wall shear and duct half-height Re τ,c ≃ 180, 360, and 550. The evolution of the Fanning friction factor f with Re is in very good agreement with experimental measurements. A significant disagreement between the DNS and previous RANS simulations was found in the prediction of the in-plane velocity, and is explained through the inability of the RANS model to properly reproduce the secondary flow present in the hexagon. The kinetic energy of the secondarymore » flow integrated over the cross-sectional area < K > yz decreases with Re in the hexagon, whereas it remains constant with Re in square ducts at comparable Reynolds numbers. Close connection between the values of Reynolds stress uw¯ on the horizontal wall close to the corner and the interaction of bursting events between the horizontal and inclined walls is found. This interaction leads to the formation of the secondary flow, and is less frequent in the hexagon as Re increases due to the 120° aperture of its vertex, whereas in the square duct the 90° corner leads to the same level of interaction with increasing Re. Analysis of turbulence statistics at the centerplane and the azimuthal variance of the mean flow and the fluctuations shows a close connection between hexagonal ducts and pipe flows, since the hexagon exhibits near-axisymmetric conditions up to a distance of around 0.15 DH measured from its center. Spanwise distributions of wall-shear stress show that in square ducts the 90° corner sets the location of a high-speed streak at a distance z + v≃50 from it, whereas in hexagons the 120° aperture leads to a shorter distance of z + v≃38. Finally, at these locations the root mean square of the wall-shear stresses exhibits an inflection point, which further shows the connections between the near-wall structures and the large-scale motions in the outer flow.« less

Pulmonary blood flow and pulmonary hypertension: Is the pulmonary circulation flowophobic or flowophilic?

PubMed Central

Kulik, Thomas J.

2012-01-01

Increased pulmonary blood flow (PBF) is widely thought to provoke pulmonary vascular obstructive disease (PVO), but the impact of wall shear stress in the lung is actually poorly defined. We examined information from patients having cardiac lesions which impact the pulmonary circulation in distinct ways, as well as experimental studies, asking how altered hemodynamics impact the risk of developing PVO. Our results are as follows: (1) with atrial septal defect (ASD; increased PBF but low PAP), shear stress may be increased but there is little tendency to develop PVO; (2) with normal PBF but increased pulmonary vascular resistance (PVR; mitral valve disease) shear stress may also be increased but risk of PVO still low; (3) with high PVR and PBF (e.g., large ventricular septal defect), wall shear stress is markedly increased and the likelihood of developing PVO is much higher than with high PBF or PAP only; and (4) with ASD, experimental and clinical observations suggest that increased PBF plus another stimulus (e.g., endothelial inflammation) may be required for PVO. We conclude that modestly increased wall shear stress (e.g., ASD) infrequently provokes PVO, and likely requires other factors to be harmful. Likewise, increased PAP seldom causes PVO. Markedly increased wall shear stress may greatly increase the likelihood of PVO, but we cannot discriminate its effect from the combined effects of increased PAP and PBF. Finally, the age of onset of increased PAP may critically impact the risk of PVO. Some implications of these observations for future investigations are discussed. PMID:23130101

Turbulence production near walls: The role of flow structures with spanwise asymmetry

NASA Technical Reports Server (NTRS)

Alfredsson, P. Henrik; Johansson, Arne V.; Kim, John

1988-01-01

Space-time evolution of near wall flow structures is described by conditional sampling methods, in which conditional averages are formed at various stages of development of shear layer structures. The development of spanwise asymmetry of the structures was found to be important in the creation of the structures and for the process of turbulence production.

Similarity between turbulent kinetic energy and temperature spectra in the near-wall region

NASA Technical Reports Server (NTRS)

Antonia, R. A.; Kim, J.

1991-01-01

The similarity between turbulent kinetic energy and temperature spectra, previously confirmed using experimental data in various turbulent shear flows, is validated in the near-wall region using direct numerical simulation data in a fully developed turbulent channel flow. The dependence of this similarity on the molecular Prandtl number is also examined.

Dispersive aortic cannulas reduce aortic wall shear stress affecting atherosclerotic plaque embolization.

PubMed

Assmann, Alexander; Gül, Fethi; Benim, Ali Cemal; Joos, Franz; Akhyari, Payam; Lichtenberg, Artur

2015-03-01

Neurologic complications during on-pump cardiovascular surgery are often induced by mobilization of atherosclerotic plaques, which is directly related to enhanced wall shear stress. In the present study, we numerically evaluated the impact of dispersive aortic cannulas on aortic blood flow characteristics, with special regard to the resulting wall shear stress profiles. An idealized numerical model of the human aorta and its branches was created and used to model straight as well as bent dispersive aortic cannulas with meshlike tips inserted in the distal ascending aorta. Standard cannulas with straight beveled or bent tips served as controls. Using a recently optimized computing method, simulations of pulsatile and nonpulsatile extracorporeal circulation were performed. Dispersive aortic cannulas reduced the maximum and average aortic wall shear stress values to approximately 50% of those with control cannulas, while the difference in local values was even larger. Moreover, under pulsatile circulation, dispersive cannulas shortened the time period during which wall shear stress values were increased. The turbulent kinetic energy was also diminished by utilizing dispersive cannulas, reducing the risk of hemolysis. In summary, dispersive aortic cannulas decrease aortic wall shear stress and turbulence during extracorporeal circulation and may therefore reduce the risk of endothelial and blood cell damage as well as that of neurologic complications caused by atherosclerotic plaque mobilization. Copyright © 2014 International Center for Artificial Organs and Transplantation and Wiley Periodicals, Inc.

Diffusion of microspheres in shear flow near a wall: use to measure binding rates between attached molecules.

PubMed Central

Pierres, A; Benoliel, A M; Zhu, C; Bongrand, P

2001-01-01

The rate and distance-dependence of association between surface-attached molecules may be determined by monitoring the motion of receptor-bearing spheres along ligand-coated surfaces in a flow chamber (Pierres et al., Proc. Natl. Acad. Sci. U.S.A. 95:9256-9261, 1998). Particle arrests reveal bond formation, and the particle-to-surface distance may be estimated from the ratio between the velocity and the wall shear rate. However, several problems are raised. First, data interpretation requires extensive computer simulations. Second, the relevance of standard results from fluid mechanics to micrometer-size particles separated from surfaces by nanometer distances is not fully demonstrated. Third, the wall shear rate must be known with high accuracy. Here we present a simple derivation of an algorithm permitting one to simulate the motion of spheres near a plane in shear flow. We check that theoretical predictions are consistent with the experimental dependence of motion on medium viscosity or particle size, and the requirement for equilibrium particle height distribution to follow Boltzman's law. The determination of the statistical relationship between particle velocity and acceleration allows one to derive the wall shear rate with 1-s(-1) accuracy and the Hamaker constant of interaction between the particle and the wall with a sensitivity better than 10(-21) J. It is demonstrated that the correlation between particle height and mean velocity during a time interval Deltat is maximal when Deltat is about 0.1-0.2 s for a particle of 1.4-microm radius. When the particle-to-surface distance ranges between 10 and 40 nm, the particle height distribution may be obtained with a standard deviation ranging between 8 and 25 nm, provided the average velocity during a 160-ms period of time is determined with 10% accuracy. It is concluded that the flow chamber allows one to detect the formation of individual bonds with a minimal lifetime of 40 ms in presence of a disruptive force of approximately 5 pN and to assess the distance dependence within the tens of nanometer range. PMID:11423392

Direct Numerical Simulation of Turbulent Couette-Poiseuille Flow With Zero Skin Friction

NASA Technical Reports Server (NTRS)

Coleman, Gary N.; Spalart, Philippe R.

2015-01-01

The near-wall scaling of mean velocity U(yw) is addressed for the case of zero skin friction on one wall of a fully turbulent channel flow. The present DNS results can be added to the evidence in support of the conjecture that U is proportional to the square root of yw in the region just above the wall at which the mean shear dU=dy = 0.

Effect of the bifurcation angle on the flow within a synthetic model of lower human airways

NASA Astrophysics Data System (ADS)

Espinosa Moreno, Andres Santiago; Duque Daza, Carlos Alberto

2016-11-01

The effect of the bifurcation angle on the flow pattern developed during respiratory inhalation and exhalation processes was explored numerically using a synthetic model of lower human airways featuring three generations of a dichotomous morphology as described by a Weibel model. Laminar flow simulations were performed for six bifurcation angles and four Reynolds numbers relevant to human respiratory flow. Numerical results of the inhalation process showed a peak displacement trend of the velocity profile towards the inner walls of the model. This displacement exhibited correlation with Dean-type secondary flow patterns, as well as with the onset and location of vortices. High wall shear stress regions on the inner walls were observed for a range of bifurcation angles. Noteworthy, specific bifurcation angles produced higher values of pressure drop, compared to the average behavior, as well as changes in the volumetric flow through the branches. Results of the simulations for exhalation process showed a different picture, mainly the appearance of symmetrical velocity profiles and the change of location of the regions of high wall shear stress. The use of this modelling methodology for biomedical applications is discussed considering the validity of the obtained results. Department of Mechanical and Mechatronics Engineering, Universidad Nacional de Colombia.

Dynamics of the blood flow in the curved artery with the rolling massage

NASA Astrophysics Data System (ADS)

Yi, H. H.; Wu, X. H.; Yao, Y. L.

2011-10-01

Arterial wall shear stress and flow velocity are important factors in the development of some arterial diseases. Here, we aim to investigate the dynamic effect of the rolling massage on the property of the blood flow in the curved artery. The distributions of flow velocity and shear stress for the blood flow are computed by the lattice Boltzmann method, and the dynamic factors under different rolling techniques are studied numerically. The study is helpful to understand the mechanism of the massage and develop the massage techniques.

Modeling of Turbulent Free Shear Flows

NASA Technical Reports Server (NTRS)

Yoder, Dennis A.; DeBonis, James R.; Georgiadis, Nicolas J.

2013-01-01

The modeling of turbulent free shear flows is crucial to the simulation of many aerospace applications, yet often receives less attention than the modeling of wall boundary layers. Thus, while turbulence model development in general has proceeded very slowly in the past twenty years, progress for free shear flows has been even more so. This paper highlights some of the fundamental issues in modeling free shear flows for propulsion applications, presents a review of past modeling efforts, and identifies areas where further research is needed. Among the topics discussed are differences between planar and axisymmetric flows, development versus self-similar regions, the effect of compressibility and the evolution of compressibility corrections, the effect of temperature on jets, and the significance of turbulent Prandtl and Schmidt numbers for reacting shear flows. Large eddy simulation greatly reduces the amount of empiricism in the physical modeling, but is sensitive to a number of numerical issues. This paper includes an overview of the importance of numerical scheme, mesh resolution, boundary treatment, sub-grid modeling, and filtering in conducting a successful simulation.

Direct simulation of polymer drag reduction in free shear flows and vortex dipoles

NASA Technical Reports Server (NTRS)

Orlandi, P.; Homsy, G. M.; Azaiez, J.

1992-01-01

One of the most efficient techniques for drag reduction is the injection of polymers near a wall which can achieve a reduction in drag up to 80 percent. Several experimental observations tend to indicate that polymers modify the turbulence structures within the buffer layer and show that the changes consist of a weakening of the strength of the streamwise vortices. In this paper, we investigate the effects of viscoelasticity on two different types of flows: the vortex dipole impinging walls to model streamwise vortices in a turbulent boundary layer and the mixing layer that represents free shear flows. For this purpose, we examined three different rheological models: the Oldroyd-B model, the Jeffrey's corotational model, and the FENE-P model.

Shear thinning and shear thickening of a confined suspension of vesicles

NASA Astrophysics Data System (ADS)

Nait Ouhra, A.; Farutin, A.; Aouane, O.; Ez-Zahraouy, H.; Benyoussef, A.; Misbah, C.

2018-01-01

Widely regarded as an interesting model system for studying flow properties of blood, vesicles are closed membranes of phospholipids that mimic the cytoplasmic membranes of red blood cells. In this study we analyze the rheology of a suspension of vesicles in a confined geometry: the suspension, bound by two planar rigid walls on each side, is subject to a shear flow. Flow properties are then analyzed as a function of shear rate γ ˙, the concentration of the suspension ϕ , and the viscosity contrast λ =ηin/ηout , where ηin and ηout are the fluid viscosities of the inner and outer fluids, respectively. We find that the apparent (or effective viscosity) of the suspension exhibits both shear thinning (decreasing viscosity with shear rate) or shear thickening (increasing viscosity with shear rate) in the same concentration range. The shear thinning or thickening behaviors appear as subtle phenomena, dependant on viscosity contrast λ . We provide physical arguments on the origins of these behaviors.

Influence of pulsatile flow on LDL transport in the arterial wall.

PubMed

Sun, Nanfeng; Wood, Nigel B; Hughes, Alun D; Thom, Simon A M; Xu, X Yun

2007-10-01

The accumulation of low-density lipoprotein (LDL) is one of the important factors in atherogenesis. Two different time scales may influence LDL transport in vivo: (1) LDL transport is coupled to blood flow with a pulse cycle of around 1 s in humans; (2) LDL transport within the arterial wall is mediated by transmural flow in the order of 10(-8) m/s. Most existing models have assumed steady flow conditions and overlooked the interactions between physical phenomena with different time scales. The objective of this study was to investigate the influence of pulsatile flow on LDL transport and examine the validity of steady flow assumption. The effect of pulsatile flow on transmural transport was incorporated by using a lumen-free cyclic (LFC) and a lumen-free time-averaged (LFTA) procedures. It is found that the steady flow simulation predicted a focal distribution in the post-stenotic region, differing from the diffuse distribution pattern produced by the pulsatile flow simulation. The LFTA procedure, in which time-averaged shear-dependent transport properties calculated from instantaneous wall shear stress (WSS) were used, predicted a similar distribution pattern to the LFC simulations. We conclude that the steady flow assumption is inadequate and instantaneous hemodynamic conditions have important influence on LDL transmural transport in arterial geometries with disturbed and complicated flow patterns.

Computational Study of the Blood Flow in Three Types of 3D Hollow Fiber Membrane Bundles

PubMed Central

Zhang, Jiafeng; Chen, Xiaobing; Ding, Jun; Fraser, Katharine H.; Ertan Taskin, M.; Griffith, Bartley P.; Wu, Zhongjun J.

2013-01-01

The goal of this study is to develop a computational fluid dynamics (CFD) modeling approach to better estimate the blood flow dynamics in the bundles of the hollow fiber membrane based medical devices (i.e., blood oxygenators, artificial lungs, and hemodialyzers). Three representative types of arrays, square, diagonal, and random with the porosity value of 0.55, were studied. In addition, a 3D array with the same porosity was studied. The flow fields between the individual fibers in these arrays at selected Reynolds numbers (Re) were simulated with CFD modeling. Hemolysis is not significant in the fiber bundles but the platelet activation may be essential. For each type of array, the average wall shear stress is linearly proportional to the Re. For the same Re but different arrays, the average wall shear stress also exhibits a linear dependency on the pressure difference across arrays, while Darcy′s law prescribes a power-law relationship, therefore, underestimating the shear stress level. For the same Re, the average wall shear stress of the diagonal array is approximately 3.1, 1.8, and 2.0 times larger than that of the square, random, and 3D arrays, respectively. A coefficient C is suggested to correlate the CFD predicted data with the analytical solution, and C is 1.16, 1.51, and 2.05 for the square, random, and diagonal arrays in this paper, respectively. It is worth noting that C is strongly dependent on the array geometrical properties, whereas it is weakly dependent on the flow field. Additionally, the 3D fiber bundle simulation results show that the three-dimensional effect is not negligible. Specifically, velocity and shear stress distribution can vary significantly along the fiber axial direction. PMID:24141394

Streaming flow from ultrasound contrast agents by acoustic waves in a blood vessel model.

PubMed

Cho, Eunjin; Chung, Sang Kug; Rhee, Kyehan

2015-09-01

To elucidate the effects of streaming flow on ultrasound contrast agent (UCA)-assisted drug delivery, streaming velocity fields from sonicated UCA microbubbles were measured using particle image velocimetry (PIV) in a blood vessel model. At the beginning of ultrasound sonication, the UCA bubbles formed clusters and translated in the direction of the ultrasound field. Bubble cluster formation and translation were faster with 2.25MHz sonication, a frequency close to the resonance frequency of the UCA. Translation of bubble clusters induced streaming jet flow that impinged on the vessel wall, forming symmetric vortices. The maximum streaming velocity was about 60mm/s at 2.25MHz and decreased to 15mm/s at 1.0MHz for the same acoustic pressure amplitude. The effect of the ultrasound frequency on wall shear stress was more noticeable. Maximum wall shear stress decreased from 0.84 to 0.1Pa as the ultrasound frequency decreased from 2.25 to 1.0MHz. The maximum spatial gradient of the wall shear stress also decreased from 1.0 to 0.1Pa/mm. This study showed that streaming flow was induced by bubble cluster formation and translation and was stronger upon sonication by an acoustic wave with a frequency near the UCA resonance frequency. Therefore, the secondary radiant force, which is much stronger at the resonance frequency, should play an important role in UCA-assisted drug delivery. Copyright © 2015 Elsevier B.V. All rights reserved.

Divergence-free smoothing for MRV data on stenosed carotid artery phantom flows

NASA Astrophysics Data System (ADS)

Im, Chaehyuk; Ko, Seungbin; Song, Simon

2017-11-01

Magnetic Resonance Velocimetry (MRV) is a versatile technique for measuring flow velocity using an MRI machine. It is frequently used for visualization and analysis of blood flows. However, it is difficult to accurately estimate hemodynamics parameters like wall shear stress (WSS) and oscillatory shear index (OSI) due to its low spatial resolution and low signal-to-noise ratio. We suggest a divergence-free smoothing (DFS) method to correct the erroneous velocity vectors obtained with MRV and improve the estimation accuracy of those parameters. Unlike previous studies on DFS for a wall-free flow, we developed a house code to apply a DFS method to a wall-bounded flow. A Hagen-Poiseuille flow and stenosed carotid artery phantom flows were measured with MRV. Each of them was analyzed for validation of the DFS code and confirmation on the accuracy improvement of hemodynamic parameters. We will discuss the effects of DFS on the improvement of the estimation accuracy of velocity vectors, WSS, OSI and etc in detail This work was supported by the National Research Foundation of Korea(NRF) Grant funded by the Korea government(MSIP) (No. 2016R1A2B3009541).

Flow topology of rare back flow events and critical points in turbulent channels and toroidal pipes

NASA Astrophysics Data System (ADS)

Chin, C.; Vinuesa, R.; Örlü, R.; Cardesa, J. I.; Noorani, A.; Schlatter, P.; Chong, M. S.

2018-04-01

A study of the back flow events and critical points in the flow through a toroidal pipe at friction Reynolds number Re τ ≈ 650 is performed and compared with the results in a turbulent channel flow at Re τ ≈ 934. The statistics and topological properties of the back flow events are analysed and discussed. Conditionally-averaged flow fields in the vicinity of the back flow event are obtained, and the results for the torus show a similar streamwise wall-shear stress topology which varies considerably for the spanwise wall-shear stress when compared to the channel flow. The comparison between the toroidal pipe and channel flows also shows fewer back flow events and critical points in the torus. This cannot be solely attributed to differences in Reynolds number, but is a clear effect of the secondary flow present in the toroidal pipe. A possible mechanism is the effect of the secondary flow present in the torus, which convects momentum from the inner to the outer bend through the core of the pipe, and back from the outer to the inner bend through the pipe walls. In the region around the critical points, the skin-friction streamlines and vorticity lines exhibit similar flow characteristics with a node and saddle pair for both flows. These results indicate that back flow events and critical points are genuine features of wall-bounded turbulence, and are not artifacts of specific boundary or inflow conditions in simulations and/or measurement uncertainties in experiments.

A rational approach to the use of Prandtl's mixing length model in free turbulent shear flow calculations

NASA Technical Reports Server (NTRS)

Rudy, D. H.; Bushnell, D. M.

1973-01-01

Prandtl's basic mixing length model was used to compute 22 test cases on free turbulent shear flows. The calculations employed appropriate algebraic length scale equations and single values of mixing length constant for planar and axisymmetric flows, respectively. Good agreement with data was obtained except for flows, such as supersonic free shear layers, where large sustained sensitivity changes occur. The inability to predict the more gradual mixing in these flows is tentatively ascribed to the presence of a significant turbulence-induced transverse static pressure gradient which is neglected in conventional solution procedures. Some type of an equation for length scale development was found to be necessary for successful computation of highly nonsimilar flow regions such as jet or wake development from thick wall flows.

Post-Treatment Hemodynamics of a Basilar Aneurysm and Bifurcation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ortega, J; Hartman, J; Rodriguez, J

2008-01-16

Aneurysm re-growth and rupture can sometimes unexpectedly occur following treatment procedures that were initially considered to be successful at the time of treatment and post-operative angiography. In some cases, this can be attributed to surgical clip slippage or endovascular coil compaction. However, there are other cases in which the treatment devices function properly. In these instances, the subsequent complications are due to other factors, perhaps one of which is the post-treatment hemodynamic stress. To investigate whether or not a treatment procedure can subject the parent artery to harmful hemodynamic stresses, computational fluid dynamics simulations are performed on a patient-specific basilarmore » aneurysm and bifurcation before and after a virtual endovascular treatment. The simulations demonstrate that the treatment procedure produces a substantial increase in the wall shear stress. Analysis of the post-treatment flow field indicates that the increase in wall shear stress is due to the impingement of the basilar artery flow upon the aneurysm filling material and to the close proximity of a vortex tube to the artery wall. Calculation of the time-averaged wall shear stress shows that there is a region of the artery exposed to a level of wall shear stress that can cause severe damage to endothelial cells. The results of this study demonstrate that it is possible for a treatment procedure, which successfully excludes the aneurysm from the vascular system and leaves no aneurysm neck remnant, to elevate the hemodynamic stresses to levels that are injurious to the immediately adjacent vessel wall.« less

A Two-Axis Direct Fluid Shear Stress Sensor

NASA Technical Reports Server (NTRS)

Adcock, Edward E.; Scott, Michael A.; Bajikar, Sateesh S.

2010-01-01

This innovation is a miniature or micro sized semiconductor sensor design that provides two axis direct non-intrusive measurement of skin friction or wall shear stress in fluid flow. The sensor is fabricated by micro-electro-mechanical system (MEMS) technology, enabling small size and low cost reproductions. The sensors have been fabricated by utilizing MEMS fabrication processes to bond a sensing element wafer to a fluid coupling wafer. This layering technique provides for an out of plane dimension that is on the same order of length as the inplane dimensions. The sensor design has the following characteristics: a shear force collecting plate with dimensions that can be tailored to various application specific requirements such as spatial resolution, temporal resolution and shear force range and resolution. This plate is located coplanar to both the sensor body and flow boundary, and is connected to a dual axis gimbal structure by a connecting column or lever arm. The dual axis gimbal structure has torsional hinges with embedded piezoresistive torsional strain gauges which provide a voltage output that is correlated to the applied shear stress (and excitation current) on force collection plate that is located on the flow boundary surface (hence the transduction method). This combination of design elements create a force concentration and resolution structure that enables the generation of a large stress on the strain gauge from the small shear stress on the flow boundary wall. This design as well as the use of back side electrical contacts establishes a non-intrusive method to quantitatively measure the shear force vector on aerodynamic bodies.

Interaction between a normal shock wave and a turbulent boundary layer at high transonic speeds. II - Wall shear stress

NASA Technical Reports Server (NTRS)

Liou, M. S.; Adamson, T. C., Jr.

1980-01-01

Asymptotic methods are used to calculate the shear stress at the wall for the interaction between a normal shock wave and a turbulent boundary layer on a flat plate. A mixing length model is used for the eddy viscosity. The shock wave is taken to be strong enough that the sonic line is deep in the boundary layer and the upstream influence is thus very small. It is shown that unlike the result found for laminar flow an asymptotic criterion for separation is not found; however, conditions for incipient separation are computed numerically using the derived solution for the shear stress at the wall. Results are compared with available experimental measurements.

Direct measurements of wall shear stress by buried wire gages in a shock-wave boundary-layer interaction region

NASA Technical Reports Server (NTRS)

Murthy, V. S.; Rose, W. C.

1977-01-01

Detailed measurements of wall shear stress (skin friction) were made with specially developed buried wire gages in the interaction regions of a Mach 2.9 turbulent boundary layer with externally generated shocks. Separation and reattachment points inferred by these measurements support the findings of earlier experiments which used a surface oil flow technique and pitot profile measurements. The measurements further indicate that the boundary layer tends to attain significantly higher skin-friction values downstream of the interaction region as compared to upstream. Comparisons between measured wall shear stress and published results of some theoretical calculation schemes show that the general, but not detailed, behavior is predicted well by such schemes.

Experimental investigation of compliant wall surface deformation in a turbulent channel flow

NASA Astrophysics Data System (ADS)

Zhang, Cao; Wang, Jin; Katz, Joseph

2016-11-01

The dynamic response of a compliant wall under a turbulent channel flow is investigated by simultaneously measuring the time-resolved, 3D flow field (using tomographic PIV) and the 2D surface deformation (using interferometry). The pressure distributions are calculated by spatially integrating the material acceleration field. The Reynolds number is Reτ = 2300, and the centerline velocity (U0) is 15% of the material shear speed. The wavenumber-frequency spectra of the wall deformation contain a non-advected low-frequency component and advected modes, some traveling downstream at U0 and others at 0.72U0. Trends in the wall dynamics are elucidated by correlating the deformation with flow variables. The spatial pressure-deformation correlations peak at y/ h 0.12 (h is half channel height), the elevation of Reynolds shear stress maximum in the log-layer. Streamwise lagging of the deformation behind the pressure is caused in part by phase-lag of the pressure with decreasing distance from the wall, and in part by material damping. Positive deformations (bumps) are preferentially associated with ejections, which involve spanwise vortices located downstream and quasi-streamwise vortices with spanwise offset, consistent with hairpin-like structures. The negative deformations (dents) are preferentially associated with pressure maxima at the transition between an upstream sweep to a downstream ejection. Sponsored by ONR.

Aortic dissection simulation models for clinical support: fluid-structure interaction vs. rigid wall models.

PubMed

Alimohammadi, Mona; Sherwood, Joseph M; Karimpour, Morad; Agu, Obiekezie; Balabani, Stavroula; Díaz-Zuccarini, Vanessa

2015-04-15

The management and prognosis of aortic dissection (AD) is often challenging and the use of personalised computational models is being explored as a tool to improve clinical outcome. Including vessel wall motion in such simulations can provide more realistic and potentially accurate results, but requires significant additional computational resources, as well as expertise. With clinical translation as the final aim, trade-offs between complexity, speed and accuracy are inevitable. The present study explores whether modelling wall motion is worth the additional expense in the case of AD, by carrying out fluid-structure interaction (FSI) simulations based on a sample patient case. Patient-specific anatomical details were extracted from computed tomography images to provide the fluid domain, from which the vessel wall was extrapolated. Two-way fluid-structure interaction simulations were performed, with coupled Windkessel boundary conditions and hyperelastic wall properties. The blood was modelled using the Carreau-Yasuda viscosity model and turbulence was accounted for via a shear stress transport model. A simulation without wall motion (rigid wall) was carried out for comparison purposes. The displacement of the vessel wall was comparable to reports from imaging studies in terms of intimal flap motion and contraction of the true lumen. Analysis of the haemodynamics around the proximal and distal false lumen in the FSI model showed complex flow structures caused by the expansion and contraction of the vessel wall. These flow patterns led to significantly different predictions of wall shear stress, particularly its oscillatory component, which were not captured by the rigid wall model. Through comparison with imaging data, the results of the present study indicate that the fluid-structure interaction methodology employed herein is appropriate for simulations of aortic dissection. Regions of high wall shear stress were not significantly altered by the wall motion, however, certain collocated regions of low and oscillatory wall shear stress which may be critical for disease progression were only identified in the FSI simulation. We conclude that, if patient-tailored simulations of aortic dissection are to be used as an interventional planning tool, then the additional complexity, expertise and computational expense required to model wall motion is indeed justified.

Blood flow in hemodialysis catheters: a numerical simulation and microscopic analysis of in vivo-formed fibrin.

PubMed

Lucas, Thabata Coaglio; Tessarolo, Francesco; Jakitsch, Victor; Caola, Iole; Brunori, Giuliano; Nollo, Giandomenico; Huebner, Rudolf

2014-07-01

Although catheters with side holes allow high flow rate during hemodialysis, they also induce flow disturbances and create a critical hemodynamic environment that can favor fibrin deposition and thrombus formation. This study compared the blood flow and analyzed the influence of shear stress and shear rate in fibrin deposition and thrombus formation in nontunneled hemodialysis catheters with unobstructed side holes (unobstructed device) or with some side holes obstructed by blood thrombi (obstructed device). Computational fluid dynamics (CFD) was performed to simulate realistic blood flow under laminar and turbulent conditions. The results from the numerical simulations were compared with the fibrin distribution and thrombus architecture data obtained from scanning electron microscopy (SEM) and two photons laser scanning microscopy (TPLSM) on human thrombus formed in catheters removed from patients. CFD showed that regions of flow eddies and separation were mainly found in the venous holes region. TPLSM characterization of thrombi and fibrin structure in patient samples showed fibrin formations in accordance with simulated flux dynamics. Under laminar flow conditions, the wall shear stress close to border holes increased from 87.3±0.2 Pa in the unobstructed device to 176.2±0.5 Pa in the obstructed one. Under turbulent flow conditions, the shear stress increased by 47% when comparing the obstructed to the unobstructed catheter. The shear rates were generally higher than 5000/s and therefore sufficient to induce fibrin deposition. This findings were supported by SEM data documenting a preferential fibrin arrangement on side hole walls. Copyright © 2013 International Center for Artificial Organs and Transplantation and Wiley Periodicals, Inc.

Pulsatile flow of non-Newtonian blood fluid inside stenosed arteries: Investigating the effects of viscoelastic and elastic walls, arteriosclerosis, and polycythemia diseases.

PubMed

Nejad, A Abbas; Talebi, Z; Cheraghali, D; Shahbani-Zahiri, A; Norouzi, M

2018-02-01

In this study, the interaction of pulsatile blood flow with the viscoelastic walls of the axisymmetric artery is numerically investigated for different severities of stenosis. The geometry of artery is modeled by an axisymmetric cylindrical tube with a symmetric stenosis in a two-dimensional case. The effects of stenosis severity on the axial velocity profile, pressure distribution, streamlines, wall shear stress, and wall radial displacement for the viscoelastic artery are also compared to the elastics artery. Furthermore, the effects of atherosclerosis and polycythemia diseases on the hemodynamics and the mechanical behavior of arterial walls are investigated. The pulsatile flow of non-Newtonian blood is simulated inside the viscoelastic artery using the COMSOL Multiphysics software (version 5) and by employing the fluid-structure interaction (FSI) method and the arbitrary Lagrangian-Eulerian (ALE) method. Moreover, finite element method (FEM) is used to solve the governing equations on the unstructured grids. For modeling the non-Newtonian blood fluid and the viscoelastic arterial wall, the modified Casson model, and generalized Maxwell model are used, respectively. According to the results, with stenosis severity increasing from 25% to 75% at the time of maximum volumetric flow rate, the maximum value of axial velocity and its gradient increase 7.9 and 19.6 times, and the maximum wall shear stress of viscoelastic wall increases 24.2 times in the constriction zone. With the progression of the atherosclerosis disease (fivefold growth of arterial elastic modulus), the wall radial displacement of viscoelastic arterial walls decreases nearly 40%. In this study, axial velocity profile, pressure distribution, streamlines, wall radial displacement, and wall shear stress were examined for different percentages of stenosis (25%, 50%, and 75%). The atherosclerosis disease was investigated by the fivefold growth of viscoelastic arterial elastic modulus and polycythemia disease was examined by the 21-fold increase in the yield stress of the blood fluid. Furthermore, the comparison of results between the elastic and viscoelastic arterial walls shows that the wall radial displacement for viscoelastic artery is lower than that for the elastic artery as much as 21.7% for the severe stenosis of 75%. Copyright © 2017 Elsevier B.V. All rights reserved.

Role of mixed boundaries on flow in open capillary channels with curved air-water interfaces.

PubMed

Zheng, Wenjuan; Wang, Lian-Ping; Or, Dani; Lazouskaya, Volha; Jin, Yan

2012-09-04

Flow in unsaturated porous media or in engineered microfluidic systems is dominated by capillary and viscous forces. Consequently, flow regimes may differ markedly from conventional flows, reflecting strong interfacial influences on small bodies of flowing liquids. In this work, we visualized liquid transport patterns in open capillary channels with a range of opening sizes from 0.6 to 5.0 mm using laser scanning confocal microscopy combined with fluorescent latex particles (1.0 μm) as tracers at a mean velocity of ∼0.50 mm s(-1). The observed velocity profiles indicate limited mobility at the air-water interface. The application of the Stokes equation with mixed boundary conditions (i.e., no slip on the channel walls and partial slip or shear stress at the air-water interface) clearly illustrates the increasing importance of interfacial shear stress with decreasing channel size. Interfacial shear stress emerges from the velocity gradient from the adjoining no-slip walls to the center where flow is trapped in a region in which capillary forces dominate. In addition, the increased contribution of capillary forces (relative to viscous forces) to flow on the microscale leads to increased interfacial curvature, which, together with interfacial shear stress, affects the velocity distribution and flow pattern (e.g., reverse flow in the contact line region). We found that partial slip, rather than the commonly used stress-free condition, provided a more accurate description of the boundary condition at the confined air-water interface, reflecting the key role that surface/interface effects play in controlling flow behavior on the nanoscale and microscale.

Computational modelling of flow and tip variations of aortic cannulae in cardiopulmonary bypass procedure

NASA Astrophysics Data System (ADS)

Thomas, Siti A.; Empaling, Shirly; Darlis, Nofrizalidris; Osman, Kahar; Dillon, Jeswant; Taib, Ishkrizat; Khudzari, Ahmad Zahran Md

2017-09-01

Aortic cannulation has been the gold standard for maintaining cardiovascular function during open heart surgery while being connected onto the heart lung machine. These cannulation produces high velocity outflow which may lead to adverse effect on patient condition, especially sandblasting effect on aorta wall and blood cells damage. This paper reports a novel design that was able to decrease high velocity outflow. There were three design factors of that was investigated. The design factors consist of the cannula type, the flow rate, and the cannula tip design which result in 12 variations. The cannulae type used were the spiral flow inducing cannula and the standard cannula. The flow rates are varied from three to five litres per minute (lpm). Parameters for each cannula variation included maximum velocity within the aorta, pressure drop, wall shear stress (WSS) area exceeding 15 Pa, and impinging velocity on the aorta wall were evaluated. Based on the result, spiral flow inducing cannulae is proposed as a better alternatives due to its ability to reduce outflow velocity. Meanwhile, the pressure drop of all variations are less than the limit of 100 mmHg, although standard cannulae yielded better result. All cannulae show low reading of wall shear stress which decrease the possibilities for atherogenesis formation. In conclusion, as far as velocity is concerned, spiral flow is better compared to standard flow across all cannulae variations.

The Effects of Acoustic Treatment on Pressure Disturbances From a Supersonic Jet in a Circular Duct

NASA Technical Reports Server (NTRS)

Dahl, Milo D.

1996-01-01

The pressure disturbances generated by an instability wave in the shear layer of a supersonic jet are studied for an axisymmetric jet inside a lined circular duct. For the supersonic jet, locally linear stability analysis with duct wall boundary conditions is used to calculate the eigenvalues and the eigenfunctions at each axial location. These values are used to determine the growth rates and phase velocities of the instability waves and the near field pressure disturbance patterns. The study is confined to the dominant Kelvin-Helmholtz instability mode and to the region just downstream of the nozzle exit where the shear layer is growing but is still small in size compared to the radius of the duct. Numerical results are used to study the effects of changes in the outer flow, growth in the shear layer thickness, wall distance, and wall impedance, and the effects of these changes on non-axisymmetric modes. The primary results indicate that the effects of the duct wall on stability characteristics diminish as the outer flow increases and as the jet azimuthal mode number increases. Also, wall reflections are reduced when using a finite impedance boundary condition at the wall; but in addition, reflections are reduced and growth rates diminished by keeping the imaginary part of the impedance negative when using the negative exponential for the harmonic dependence.

Acoustic microstreaming due to an ultrasound contrast microbubble near a wall

NASA Astrophysics Data System (ADS)

Mobadersany, Nima; Sarkar, Kausik

2017-11-01

In an ultrasound field, in addition to the sinusoidal motion of fluid particles, particles experience a steady streaming velocity due to nonlinear second order effects. Here, we have simulated the microstreaming flow near a plane rigid wall caused by the pulsations of contrast microbubbles. Although these microbubbles were initially developed as a contrast enhancing agents for ultrasound imaging, they generate additional therapeutic effects that can be harnessed for targeted drug delivery or blood brain barrier (BBB) opening. The microbubbles have a gas core coated with a stabilizing layer of lipids or proteins. We use analytical models as well as boundary element (BEM) simulation to simulate the flow around these bubbles implementing interfacial rheology models for the coating. The microstreaming flow is characterized by two wall bounded vortices. The size of the vortices decreases with the decrease of the separation from the wall. The vortex-induced shear stress is simulated and analyzed as a function of excitation parameters and geometry. These microstreaming shear stress plays a critical role in increasing the membrane permeability facilitating drug delivery or rupturing biological tissues.

Laminar flow in a microchannel with superhydrophobic walls exhibiting transverse ribs

NASA Astrophysics Data System (ADS)

Davies, J.; Maynes, D.; Webb, B. W.; Woolford, B.

2006-08-01

One approach recently proposed for reducing the frictional resistance to liquid flow in microchannels is the patterning of microribs and cavities on the channel walls. When treated with a hydrophobic coating, the liquid flowing in the microchannel wets only the surfaces of the ribs, and does not penetrate the cavities, provided the pressure is not too high. The net result is a reduction in the surface contact area between channel walls and the flowing liquid. For microribs and cavities that are aligned normal to the channel axis (principal flow direction), these micropatterns form a repeating, periodic structure. This paper presents results of a study exploring the momentum transport in a parallel-plate microchannel with such microengineered walls. The investigation explored the entire laminar flow Reynolds number range and characterized the influence of the vapor cavity depth on the overall flow field. The liquid-vapor interface (meniscus) in the cavity regions is treated as flat in the numerical analysis and two conditions are explored with regard to the cavity region: (1) The liquid flow at the liquid-vapor interface is treated as shear-free (vanishing viscosity in the vapor region), and (2) the liquid flow in the microchannel core and the vapor flow within the cavity are coupled by matching the velocity and shear stress at the interface. Regions of slip and no-slip behavior exist and the velocity field shows distinct variations from classical laminar flow in a parallel-plate channel. The local streamwise velocity profiles, interfacial velocity distributions, and maximum interfacial velocities are presented for a number of scenarios and provide a sound understanding of the local flow physics. The predictions and accompanying measurements reveal that significant reductions in the frictional pressure drop (enhancement in effective fluid slip at the channel walls) can be achieved relative to the classical smooth-channel Stokes flow. Reductions in the friction factor and enhancements in the fluid slip are greater as the cavity-to-rib length ratio is increased (increasing shear-free fraction) and as the channel hydraulic diameter is decreased. The results also show that the slip length and average friction factor-Reynolds number product exhibit a flow Reynolds dependence. Furthermore, the predictions reveal the global impact of the vapor cavity depth on the overall frictional resistance.

Effects of Disturbed Flow on Vascular Endothelium: Pathophysiological Basis and Clinical Perspectives

PubMed Central

Chiu, Jeng-Jiann; Chien, Shu

2013-01-01

Vascular endothelial cells (ECs) are exposed to hemodynamic forces, which modulate EC functions and vascular biology/pathobiology in health and disease. The flow patterns and hemodynamic forces are not uniform in the vascular system. In straight parts of the arterial tree, blood flow is generally laminar and wall shear stress is high and directed; in branches and curvatures, blood flow is disturbed with nonuniform and irregular distribution of low wall shear stress. Sustained laminar flow with high shear stress upregulates expressions of EC genes and proteins that are protective against atherosclerosis, whereas disturbed flow with associated reciprocating, low shear stress generally upregulates the EC genes and proteins that promote atherogenesis. These findings have led to the concept that the disturbed flow pattern in branch points and curvatures causes the preferential localization of atherosclerotic lesions. Disturbed flow also results in postsurgical neointimal hyperplasia and contributes to pathophysiology of clinical conditions such as in-stent restenosis, vein bypass graft failure, and transplant vasculopathy, as well as aortic valve calcification. In the venous system, disturbed flow resulting from reflux, outflow obstruction, and/or stasis leads to venous inflammation and thrombosis, and hence the development of chronic venous diseases. Understanding of the effects of disturbed flow on ECs can provide mechanistic insights into the role of complex flow patterns in pathogenesis of vascular diseases and can help to elucidate the phenotypic and functional differences between quiescent (nonatherogenic/nonthrombogenic) and activated (atherogenic/thrombogenic) ECs. This review summarizes the current knowledge on the role of disturbed flow in EC physiology and pathophysiology, as well as its clinical implications. Such information can contribute to our understanding of the etiology of lesion development in vascular niches with disturbed flow and help to generate new approaches for therapeutic interventions. PMID:21248169

Buoyancy Driven Shear Flows of Bubble Suspensions

NASA Technical Reports Server (NTRS)

Koch, D. L.; Hill, R. J.; Chellppannair, T.; Zenit, R.; Zenit, R.; Spelt, P. D. M.

1999-01-01

In this work the gas volume fraction and the root-mean-squared fluid velocity are measured in buoyancy driven shear flows of bubble suspensions in a tall, inclined, rectangular channel. The experiments are performed under conditions where We << 1a nd Re >> 1, for which comparisons are made with kinetic theory and numerical simulations. Here Re = gamma(a(exp 2)/nu is the Reynolds number and We = rho(gamma(exp 2))a(exp 3)/sigma is the Weber number; gamma is the shear rate, a is the bubble radius, nu is the kinematic viscosity of the liquid, rho is the density of the liquid, and sigma is the surface tension of the gas/liquid interface. Kang et al. calculated the bubble phase pressure and velocity variance of sheared bubble suspensions under conditions where the bubbles are spherical and the liquid phase velocity field can be approximated using potential flow theory, i.e. We= 0 and Re >> 1. Such conditions can be achieved in an experiment using gas bubbles, with a radius of O(0.5mm), in water. The theory requires that there be no average relative motion of the gas and liquid phases, hence the motivation for an experimental program in microgravity. The necessity of performing preliminary, Earth based experiments, however, requires performing experiments where the gas phase rises in the liquid, which significantly complicates the comparison of experiments with theory. Rather than comparing experimental results with theory for a uniform, homogeneous shear flow, experiments can be compared directly with solutions of the averaged equations of motion for bubble suspensions. This requires accounting for the significant lift force acting on the gas phase when the bubbles rise parallel to the average velocity of the sheared suspension. Shear flows can be produced in which the bubble phase pressure gradient, arising from shear induced collisions amongst the bubbles, balances a body force (centrifugal or gravitational) on the gas phase. A steady, non-uniform gas volume fraction can be measured, from which the bubble phase pressure gradient can be obtained and compared to theory and numerical simulations. The presence of bounding walls further complicates the experiments, since the detailed interactions of the bubbles with bounding walls is not well understood, especially in the presence of gravity, where the momentum and energy exchange depends on the inclination of the wall.

Modeling of flow-induced shear stress applied on 3D cellular scaffolds: Implications for vascular tissue engineering.

PubMed

Lesman, Ayelet; Blinder, Yaron; Levenberg, Shulamit

2010-02-15

Novel tissue-culture bioreactors employ flow-induced shear stress as a means of mechanical stimulation of cells. We developed a computational fluid dynamics model of the complex three-dimensional (3D) microstructure of a porous scaffold incubated in a direct perfusion bioreactor. Our model was designed to predict high shear-stress values within the physiological range of those naturally sensed by vascular cells (1-10 dyne/cm(2)), and will thereby provide suitable conditions for vascular tissue-engineering experiments. The model also accounts for cellular growth, which was designed as an added cell layer grown on all scaffold walls. Five model variants were designed, with geometric differences corresponding to cell-layer thicknesses of 0, 50, 75, 100, and 125 microm. Four inlet velocities (0.5, 1, 1.5, and 2 cm/s) were applied to each model. Wall shear-stress distribution and overall pressure drop calculations were then used to characterize the relation between flow rate, shear stress, cell-layer thickness, and pressure drop. The simulations showed that cellular growth within 3D scaffolds exposes cells to elevated shear stress, with considerably increasing average values in correlation to cell growth and inflow velocity. Our results provide in-depth analysis of the microdynamic environment of cells cultured within 3D environments, and thus provide advanced control over tissue development in vitro. 2009 Wiley Periodicals, Inc.

Non-Newtonian blood flow dynamics in a right internal carotid artery with a saccular aneurysm

NASA Astrophysics Data System (ADS)

Valencia, Alvaro; Zarate, Alvaro; Galvez, Marcelo; Badilla, Lautaro

2006-02-01

Flow dynamics plays an important role in the pathogenesis and treatment of cerebral aneurysms. The temporal and spatial variations of wall shear stress in the aneurysm are hypothesized to be correlated with its growth and rupture. In addition, the assessment of the velocity field in the aneurysm dome and neck is important for the correct placement of endovascular coils. This work describes the flow dynamics in a patient-specific model of carotid artery with a saccular aneurysm under Newtonian and non-Newtonian fluid assumptions. The model was obtained from three-dimensional rotational angiography image data and blood flow dynamics was studied under physiologically representative waveform of inflow. The three-dimensional continuity and momentum equations for incompressible and unsteady laminar flow were solved with a commercial software using non-structured fine grid with 283 115 tetrahedral elements. The intra-aneurysmal flow shows complex vortex structure that change during one pulsatile cycle. The effect of the non-Newtonian properties of blood on the wall shear stress was important only in the arterial regions with high velocity gradients, on the aneurysmal wall the predictions with the Newtonian and non-Newtonian blood models were similar.

Lattice Boltzmann Study of Bubbles on a Patterned Superhydrophobic Surface under Shear Flow

NASA Astrophysics Data System (ADS)

Chen, Wei; Wang, Kai; Hou, Guoxiang; Leng, Wenjun

2018-01-01

This paper studies shear flow over a 2D patterned superhydrophobic surface using lattice Boltzmann method (LBM). Single component Shan-Chen multiphase model and Carnahan-Starling EOS are adopted to handle the liquid-gas flow on superhydrophobic surface with entrapped micro-bubbles. The shape of bubble interface and its influence on slip length under different shear rates are investigated. With increasing shear rate, the bubble interface deforms. Then the contact lines are depinned from the slot edges and move downstream. When the shear rate is high enough, a continuous gas layer forms. If the protrusion angle is small, the gas layer forms and collapse periodically, and accordingly the slip length changes periodically. While if the protrusion angle is large, the gas layer is steady and separates the solid wall from liquid, resulting in a very large slip length.

Blood flow dynamic improvement with aneurysm repair detected by a patient-specific model of multiple aortic aneurysms.

PubMed

Sughimoto, Koichi; Takahara, Yoshiharu; Mogi, Kenji; Yamazaki, Kenji; Tsubota, Ken'ichi; Liang, Fuyou; Liu, Hao

2014-05-01

Aortic aneurysms may cause the turbulence of blood flow and result in the energy loss of the blood flow, while grafting of the dilated aorta may ameliorate these hemodynamic disturbances, contributing to the alleviation of the energy efficiency of blood flow delivery. However, evaluating of the energy efficiency of blood flow in an aortic aneurysm has been technically difficult to estimate and not comprehensively understood yet. We devised a multiscale computational biomechanical model, introducing novel flow indices, to investigate a single male patient with multiple aortic aneurysms. Preoperative levels of wall shear stress and oscillatory shear index (OSI) were elevated but declined after staged grafting procedures: OSI decreased from 0.280 to 0.257 (first operation) and 0.221 (second operation). Graftings may strategically counter the loss of efficient blood delivery to improve hemodynamics of the aorta. The energy efficiency of blood flow also improved postoperatively. Novel indices of pulsatile pressure index (PPI) and pulsatile energy loss index (PELI) were evaluated to characterize and quantify energy loss of pulsatile blood flow. Mean PPI decreased from 0.445 to 0.423 (first operation) and 0.359 (second operation), respectively; while the preoperative PELI of 0.986 dropped to 0.820 and 0.831. Graftings contributed not only to ameliorate wall shear stress or oscillatory shear index but also to improve efficient blood flow. This patient-specific modeling will help in analyzing the mechanism of aortic aneurysm formation and may play an important role in quantifying the energy efficiency or loss in blood delivery.

Cold-Flow Study of Low Frequency Pressure Instability in Hybrid Rocket Motors

NASA Technical Reports Server (NTRS)

Jenkins, Rhonald M.

1997-01-01

Past experience with hybrid rockets has shown that certain motor operating conditions are conducive to the formation of low frequency pressure oscillations, or flow instabilities, within the motor. Both past and present work in the hybrid propulsion community acknowledges deficiencies in the understanding of such behavior, though it seems probable that the answer lies in an interaction between the flow dynamics and the combustion heat release. Knowledge of the fundamental flow dynamics is essential to the basic understanding of the overall stability problem. A first step in this direction was a study conducted at NASA Marshall Space Flight Center (MSFC), centered around a laboratory-scale two dimensional water flow model of a hybrid rocket motor. Principal objectives included: (1) visualization of flow and measurement of flow velocity distributions: (2) assessment of the importance of shear layer instabilities in driving motor pressure oscillations; (3) determination of the interactions between flow induced shear layers with the mainstream flow, the secondary (wall) throughflow, and solid boundaries; (4) investigation of the interactions between wall flow oscillations and the mainstream flow pressure distribution.

Turbulent transport modeling of shear flows around an aerodynamic wing. Development of turbulent near-wall model and its application to recirculating flows

NASA Technical Reports Server (NTRS)

Amano, R. S.

1982-01-01

Progress in implementing and refining two near-wall turbulence models in which the near-wall region is divided into either two or three zones is outlined. These models were successfully applied to the computation of recirculating flows. The research was further extended to obtaining experimental results of two different recirculating flow conditions in order to check the validity of the present models. Two different experimental apparatuses were set up: axisymmetric turbulent impinging jets on a flat plate, and turbulent flows in a circular pipe with a abrupt pipe expansion. It is shown that generally better results are obtained by using the present near-wall models, and among the models the three-zone model is superior to the two-zone model.

The cause and resolution of log-layer mismatch in wall-modeled LES: a new perspective and its implication in complex flows

NASA Astrophysics Data System (ADS)

Park, George; Yang, Xiang; Moin, Parviz

2017-11-01

Log-layer mismatch (LLM) refers to the erroneous shifts of the mean velocity profile in the log-law region when wall models are coupled to the LES solution at the first off-wall grid points. It is often believed that the discretization error and subgrid-scale modeling error in the highly under resolved near-wall region contaminates the first off-wall LES solution, thereby providing inaccurate input to wall models resulting in inaccurate wall shear stress. Placing the LES/wall-model interface a couple of cells away from the wall has been recommended to avoid LLM. However, its non-local nature render this method impractical for flows involving complex geometry, by incurring significant overhead in LES mesh preparation and wall-model implementation. We propose an alternative remedy for LLM which warrants the removal of LLM while utilizing the first off-wall LES data. The method is based on filtering the wall-model input either in space or in time. It is simple, easy to implement, and would be particularly well suited for unstructured-grid LES involving complex geometries. We also demonstrate that LLM is caused by excessive correlation between the wall-model input and its wall shear stress output. This research is sponsored by NASA (NNX15AU93A) and ONR (FA9550-16-1-0319).

Flow in Atherosclerotic Blood Vessels

NASA Astrophysics Data System (ADS)

Berger, Stanley A.; Stroud, Jenn S.

2000-11-01

Atherosclerotic lesions occur in arteries where there are major changes in flow structure, e.g. bifurcations and junctions. The reduction of vessel lumen alters the flow, including the mechanical forces on the walls. We have examined the flow in carotid artery bifurcations with realistic plaque contours. The unsteady, incompressible, Navier-Stokes equations are solved in finite-volume form. Steady and pulsatile flows have been analyzed for laminar and turbulent flows, using for the latter a low-Reynolds number k- ɛ model and a k-ω model. Non-Newtonian viscosity is also considered using a power-law model. In general the very irregular contours of the vessels lead to recirculating regions, strong spatial variations of wall shear stresses, and in some cases, vortex shedding. Even steady inlet flow exhibits fluctuating, unsteady behavior. Neither turbulence models captures all the physics of the flow. The flow, in fact, appears to be transitional and not fully turbulent. For unsteady flow, there are also strong temporal variations of normal and shear stresses, which together with the strong spatial variations, has important implications for the onset and progression of atherosclerotic disease.

Investigation of Particle Deposition in Internal Cooling Cavities of a Nozzle Guide Vane

NASA Astrophysics Data System (ADS)

Casaday, Brian Patrick

Experimental and computational studies were conducted regarding particle deposition in the internal film cooling cavities of nozzle guide vanes. An experimental facility was fabricated to simulate particle deposition on an impingement liner and upstream surface of a nozzle guide vane wall. The facility supplied particle-laden flow at temperatures up to 1000°F (540°C) to a simplified impingement cooling test section. The heated flow passed through a perforated impingement plate and impacted on a heated flat wall. The particle-laden impingement jets resulted in the buildup of deposit cones associated with individual impingement jets. The deposit growth rate increased with increasing temperature and decreasing impinging velocities. For some low flow rates or high flow temperatures, the deposit cones heights spanned the entire gap between the impingement plate and wall, and grew through the impingement holes. For high flow rates, deposit structures were removed by shear forces from the flow. At low temperatures, deposit formed not only as individual cones, but as ridges located at the mid-planes between impinging jets. A computational model was developed to predict the deposit buildup seen in the experiments. The test section geometry and fluid flow from the experiment were replicated computationally and an Eulerian-Lagrangian particle tracking technique was employed. Several particle sticking models were employed and tested for adequacy. Sticking models that accurately predicted locations and rates in external deposition experiments failed to predict certain structures or rates seen in internal applications. A geometry adaptation technique was employed and the effect on deposition prediction was discussed. A new computational sticking model was developed that predicts deposition rates based on the local wall shear. The growth patterns were compared to experiments under different operating conditions. Of all the sticking models employed, the model based on wall shear, in conjunction with geometry adaptation, proved to be the most accurate in predicting the forms of deposit growth. It was the only model that predicted the changing deposition trends based on flow temperature or Reynolds number, and is recommended for further investigation and application in the modeling of deposition in internal cooling cavities.

On streak spacing in wall-bounded turbulent flows

NASA Technical Reports Server (NTRS)

Hamilton, James M.; Kim, John J.

1993-01-01

The present study is a continuation of the examination by Hamilton et al. of the regeneration mechanisms of near-wall turbulence and an attempt to investigate the conjecture of Waleffe et al. The basis of this study is an extension of the 'minimal channel' approach of Jimenez and Moin that emphasizes the near-wall region and reduces the complexity of the turbulent flow by considering a plane Couette flow of near minimum Reynolds number and stream-wise and span-wise extent. Reduction of the flow Reynolds number to the minimum value which will allow turbulence to be sustained has the effect of reducing the ratio of the largest scales to the smallest scales or, equivalently, of causing the near-wall region to fill more of the area between the channel walls. A plane Couette flow was chosen for study since this type of flow has a mean shear of a single sign, and at low Reynolds numbers, the two wall regions are found to share a single set of structures.

Effect of PEGylation on ligand-based targeting of drug carriers to the vascular wall in blood flow.

PubMed

Onyskiw, Peter J; Eniola-Adefeso, Omolola

2013-09-03

The blood vessel wall plays a prominent role in the development of many life-threatening diseases and as such is an attractive target for treatment. To target diseased tissue, particulate drug carriers often have their surfaces modified with antibodies or epitopes specific to vascular wall-expressed molecules, along with poly(ethylene glycol) (PEG) to improve carrier blood circulation time. However, little is known about the effect of poly(ethylene glycol) on carrier adhesion dynamics-specifically in blood flow. Here we examine the influence of different molecular weight PEG spacers on particle adhesion in blood flow. Anti-ICAM-1 or Sialyl Lewis(a) were grafted onto polystyrene 2 μm and 500 nm spheres via PEG spacers and perfused in blood over activated endothelial cells at physiological shear conditions. PEG spacers were shown to improve, reduce, or have no effect on the binding density of targeted-carriers depending on the PEG surface conformation, shear rate, and targeting moiety.

Roughness topographical effects on mean momentum and stress budgets in developed turbulent channel flows

NASA Astrophysics Data System (ADS)

Aghaei Jouybari, Mostafa; Yuan, Junlin

2017-11-01

Direct numerical simulations of turbulent channel flows are carried out over two surfaces: a synthesized sand-grain surface and a realistic turbine roughness that is characterized by more prominent large-scale surface features. To separate the effects of wall-normal variation of the roughness area fraction from the (true) variation of flow statistics, the governing equations are area-averaged using intrinsic averaging, contrary to the usually practice based on the total area (i.e., superficial averaging). Additional terms appear in the mean-momentum equation resulted from the wall-normal variation of the solid fraction and play a role in the near-wall balance. Results from surfaces with a step solidity function (e.g., cubes) will also be discussed. Compared to the sand grains, the turbine surface generates stronger form-induced fluctuations, despite weaker dispersive shear stress. This is associated with more significant form-induced productions (comparable to shear production) in Reynolds stress budgets, weaker pressure work, and, consequently, more anisotropic redistribution of turbulent kinetic energy in the roughness sublayer, which potentially leads to different turbulent responses between the two surfaces in non-equilibrium flows.

Effect of bending on the dynamics and wrinkle formation for a capsule in shear flow

NASA Astrophysics Data System (ADS)

Salsac, Anne-Virginie; Dupont, Claire; Barthes-Biesel, Dominique; Vidrascu, Marina; Le Tallec, Patrick

2014-11-01

When microcapsules are subjected to an external flow, the droplets enclosed within a thin hyperelastic wall undergo large deformations, which often lead to buckling of the thin capsule wall. The objective is to study numerically an initially spherical capsule in shear flow and analyze the influence of the membrane bending rigidity on the capsule dynamics and wrinkle formation. The 3D fluid-structure interactions are modeled coupling a boundary integral method to solve for the internal and external Stokes flows with a thin shell finite element method to solve for the wall deformation. Hyperelastic constitutive laws are implemented to model the deformation of the capsule mid-surface and the generalized Hooke's law for the bending effects. We show that the capsule global motion and deformation are mainly governed by in-plane membrane tensions and are marginally influenced by the bending stiffness Ks. The bending stiffness, however, plays a role locally in regions of compressive tensions. The wrinkle wavelength depends on Ks following a power law, which provides an experimental technique to determine the value of Ks through inverse analysis.

Computational Analysis of Human Blood Flow

NASA Astrophysics Data System (ADS)

Panta, Yogendra; Marie, Hazel; Harvey, Mark

2009-11-01

Fluid flow modeling with commercially available computational fluid dynamics (CFD) software is widely used to visualize and predict physical phenomena related to various biological systems. In this presentation, a typical human aorta model was analyzed assuming the blood flow as laminar with complaint cardiac muscle wall boundaries. FLUENT, a commercially available finite volume software, coupled with Solidworks, a modeling software, was employed for the preprocessing, simulation and postprocessing of all the models.The analysis mainly consists of a fluid-dynamics analysis including a calculation of the velocity field and pressure distribution in the blood and a mechanical analysis of the deformation of the tissue and artery in terms of wall shear stress. A number of other models e.g. T branches, angle shaped were previously analyzed and compared their results for consistency for similar boundary conditions. The velocities, pressures and wall shear stress distributions achieved in all models were as expected given the similar boundary conditions. The three dimensional time dependent analysis of blood flow accounting the effect of body forces with a complaint boundary was also performed.

Orbitally shaken shallow fluid layers. II. An improved wall shear stress model

NASA Astrophysics Data System (ADS)

Alpresa, Paola; Sherwin, Spencer; Weinberg, Peter; van Reeuwijk, Maarten

2018-03-01

A new model for the analytical prediction of wall shear stress distributions at the base of orbitally shaken shallow fluid layers is developed. This model is a generalisation of the classical extended Stokes solution and will be referred to as the potential theory-Stokes model. The model is validated using a large set of numerical simulations covering a wide range of flow regimes representative of those used in laboratory experiments. It is demonstrated that the model is in much better agreement with the simulation data than the classical Stokes solution, improving the prediction in 63% of the studied cases. The central assumption of the model—which is to link the wall shear stress with the surface velocity—is shown to hold remarkably well over all regimes covered.

Calculations of wall shear stress in harmonically oscillated turbulent pipe flow using a low-Reynolds-number {kappa}-{epsilon} model

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ismael, J.O.; Cotton, M.A.

1996-03-01

The low-Reynolds-number {kappa}-{epsilon} turbulence model of Launder and Sharma is applied to the calculation of wall shear stress in spatially fully-developed turbulent pipe flow oscillated at small amplitudes. It is believed that the present study represents the first systematic evaluation of the turbulence closure under consideration over a wide range of frequency. Model results are well correlated in terms of the parameter {omega}{sup +} = {omega}{nu}/{bar U}{sub {tau}}{sup 2} at high frequencies, whereas at low frequencies there is an additional Reynolds number dependence. Comparison is made with the experimental data of Finnicum and Hanratty.

The effect of neutrally buoyant finite-size particles on channel flows in the laminar-turbulent transition regime

NASA Astrophysics Data System (ADS)

Loisel, Vincent; Abbas, Micheline; Masbernat, Olivier; Climent, Eric

2013-12-01

The presence of finite-size particles in a channel flow close to the laminar-turbulent transition is simulated with the Force Coupling Method which allows two-way coupling with the flow dynamics. Spherical particles with channel height-to-particle diameter ratio of 16 are initially randomly seeded in a fluctuating flow above the critical Reynolds number corresponding to single phase flow relaminarization. When steady-state is reached, the particle volume fraction is homogeneously distributed in the channel cross-section (ϕ ≅ 5%) except in the near-wall region where it is larger due to inertia-driven migration. Turbulence statistics (intensity of velocity fluctuations, small-scale vortical structures, wall shear stress) calculated in the fully coupled two-phase flow simulations are compared to single-phase flow data in the transition regime. It is observed that particles increase the transverse r.m.s. flow velocity fluctuations and they break down the flow coherent structures into smaller, more numerous and sustained eddies, preventing the flow to relaminarize at the single-phase critical Reynolds number. When the Reynolds number is further decreased and the suspension flow becomes laminar, the wall friction coefficient recovers the evolution of the laminar single-phase law provided that the suspension viscosity is used in the Reynolds number definition. The residual velocity fluctuations in the suspension correspond to a regime of particulate shear-induced agitation.

Effects of Aortic Irregularities on the Blood Flow

NASA Astrophysics Data System (ADS)

Gutmark-Little, Iris; Prahl-Wittberg, Lisa; van Wyk, Stevin; Mihaescu, Mihai; Fuchs, Laszlo; Backeljauw, Philippe; Gutmark, Ephraim

2013-11-01

Cardiovascular defects characterized by geometrical anomalies of the aorta and its effect on the blood flow are investigated. The flow characteristics change with the aorta geometry and the rheological properties of the blood. Flow characteristics such as wall shear stress often play an important role in the development of vascular disease. In the present study, blood is considered to be non-Newtonian and is modeled using the Quemada model, an empirical model that is valid for different red blood cell loading. Three patient-specific aortic geometries are studied using Large Eddy Simulations (LES). The three geometries represent malformations that are typical in patients populations having a genetic disorder called Turner syndrome. The results show a highly complex flow with regions of recirculation that are enhanced in two of the three aortas. Moreover, blood flow is diverted, due to the malformations, from the descending aorta to the three side branches of the arch. The geometry having an elongated transverse aorta has larger areas of strong oscillatory wall shear stress.

A general MHD formulation for plasmas with flow and resistive walls

DOE Office of Scientific and Technical Information (OSTI.GOV)

Guazzotto, L.; Freidberg, J. P.; Betti, R.

2006-11-30

Toroidal rotation, either induced by means of neutral beams (e.g. in NSTX and DIII-D) or appearing spontaneously (e.g. in Alcator C-Mod, JET and Tore Supra) is routinely observed in modem tokamak experiments. Poloidal rotation is also commonly observed, in particular in the edge region of the plasma. Plasma rotation has a major effect on plasma stability. Flow and flow shear stabilize external modes such as the resistive wall mode (as observed e.g. in DIII-D), suppress turbulence when the flow shear is large enough, and also have a significant influence on the stability and nonlinear evolution of the internal kink andmore » ballooning modes. Flow shear can in particular have both a stabilizing (by breaking up unstable structures) and destabilizing (through the Kelvin-Helmoltz mechanism) effect. A self-consistent analysis of the effect of rotation requires the use of numerical tools. In this work, we present a general eigenvalue formulation based on a variational principle stability analysis, including arbitrary (both toroidal and poloidal) plasma rotation and a thin resistive wall of arbitrary shape and resistivity. It is shown that the problem can always be reduced to a classic eigenvalue formulation of the kind i{omega}A double underbar {center_dot} {zeta}-vector = B double underbar {center_dot} {zeta}-vector, where {zeta}-vector is the unknown eigenvector related to the plasma displacement, and {omega} the (complex) evolution frequency of the perturbation. The formulation is well suited for a finite element analysis.« less

Role of large-scale motions to turbulent inertia in turbulent pipe and channel flows

NASA Astrophysics Data System (ADS)

Hwang, Jinyul; Lee, Jin; Sung, Hyung Jin

2015-11-01

The role of large-scale motions (LSMs) to the turbulent inertia (TI) term (the wall-normal gradient of the Reynolds shear stress) is examined in turbulent pipe and channel flows at Reτ ~ 930 . The TI term in the mean momentum equation represents the net force of inertia exerted by the Reynolds shear stress. Although the turbulence statistics characterizing the internal turbulent flows are similar close to the wall, the TI term differs in the logarithmic region due to the different characteristics of LSMs (λx > 3 δ) . The contribution of the LSMs to the TI term and the Reynolds shear stress in the channel flow is larger than that in the pipe flow. The LSMs in the logarithmic region act like a mean momentum source (where TI >0) even the TI profile is negative above the peak of the Reynolds shear stress. The momentum sources carried by the LSMs are related to the low-speed regions elongated in the downstream, revealing that momentum source-like motions occur in the upstream position of the low-speed structure. The streamwise extent of this structure is relatively long in the channel flow, whereas the high-speed regions on the both sides of the low-speed region in the channel flow are shorter and weaker than those in the pipe flow. This work was supported by the Creative Research Initiatives (No. 2015-001828) program of the National Research Foundation of Korea (MSIP) and partially supported by KISTI under the Strategic Supercomputing Support Program.

The practicality of defensive ice walls: How would the great ice wall in Game of Thrones hold up?

NASA Astrophysics Data System (ADS)

Truffer, M.

2017-12-01

The Game of Thrones great ice wall is a colossal feature stretching several hundred miles and over 200 m high. Its purpose is to defend the realm from the wildlings. It is generally pictured as a near vertical wall. An ice wall of these proportions poses interesting challenges, mainly because ice acts as a non-linear shear-thinning fluid. A 200 m high vertical wall would create a large effective stress near its base of almost 1.8 MPa. Typical stresses responsible for ice flow in glaciers and ice sheets are more than a magnitude lower (0.1 MPa). Extrapolating a commonly used flow law for temperate ice to such high stresses would lead to strain rates at the bottom of the wall in excess of 1/day, meaning the wall would rapidly collapse and spread laterally under its own weight. To keep the wall stable, it would help to cool it significantly, as the flow of ice is also very temperature dependent. Cooling to a chilly -40 C would reduce strain rates by two orders of magnitude, but this still leads to significant slumping of the wall within just a few weeks. A time-dependent similarity solution for simplified ice flow equations that describe the evolving shape of the ice wall was provided by Halfar (1981), and demonstrates the rapid decay of the wall. A simple estimate can be derived by assuming that ice is a perfectly plastic fluid, able to maintain a basal shear stress of about 0.1 MPa. A stable ice wall would then spread laterally to about 4 km width. The resulting slope would only be steep at the very margin and the ice wall would loose much of its defensive capabilities. I conclude that the ice wall as proposed would not be a practicable defense under typical Earth conditions, and special magical powers would be necessary to maintain its shape, even for just a few days.

Numerical simulation of adverse-pressure-gradient boundary layer with or without roughness

NASA Astrophysics Data System (ADS)

Mottaghian, Pouya; Yuan, Junlin; Piomelli, Ugo

2014-11-01

Large-eddy and direct numerical simulations are carried out on flat-plate boundary layer over smooth and rough surfaces, with adverse pressure gradient.The deceleration is achieved by imposing a wall-normal freestream velocity profile, and is strong enough to cause separation at the wall. The Reynolds number based on momentum thickness and freestream velocity at inlet is 600. Numerical sandgrain roughness is applied based on an immersed boundary method, yielding a flow that is transitionally rough. The turbulence intensity increases before separation, and reaches a higher value for the rough case, indicating stronger mixing. Roughness also causes higher momentum deficit near the wall, leading to earlier separation. This is consistent with previous observation made on rough-wall flow separation over a ramp. In both cases, the turbulent kinetic energy peaks inside the shear layer above the detachment region, with higher values in the rough case; it then decreases approaching the reattachment region. Near the wall inside the separation bubble, the near-zero turbulent intensity indicates that the turbulent structures are lifted up in the separation region. Compared with the smooth case, the shear layer is farther from the wall and the reattachment length is longer on the rough wall.

Review Article: Advances in modeling of bed particle entrainment sheared by turbulent flow

NASA Astrophysics Data System (ADS)

Dey, Subhasish; Ali, Sk Zeeshan

2018-06-01

Bed particle entrainment by turbulent wall-shear flow is a key topic of interest in hydrodynamics because it plays a major role to govern the planetary morphodynamics. In this paper, the state-of-the-art review of the essential mechanisms governing the bed particle entrainment by turbulent wall-shear flow and their mathematical modeling is presented. The paper starts with the appraisal of the earlier multifaceted ideas in modeling the particle entrainment highlighting the rolling, sliding, and lifting modes of entrainment. Then, various modeling approaches of bed particle entrainment, such as deterministic, stochastic, and spatiotemporal approaches, are critically analyzed. The modeling criteria of particle entrainment are distinguished for hydraulically smooth, transitional, and rough flow regimes. In this context, the responses of particle size, particle exposure, and packing condition to the near-bed turbulent flow that shears the particles to entrain are discussed. From the modern experimental outcomes, the conceptual mechanism of particle entrainment from the viewpoint of near-bed turbulent coherent structures is delineated. As the latest advancement of the subject, the paper sheds light on the origin of the primitive empirical formulations of bed particle entrainment deriving the scaling laws of threshold flow velocity of bed particle motion from the perspective of the phenomenological theory of turbulence. Besides, a model framework that provides a new look on the bed particle entrainment phenomenon stemming from the stochastic-cum-spatiotemporal approach is introduced. Finally, the future scope of research is articulated with open questions.

Correlation of laser-Doppler-velocity measurements and endothelial cell shape in a stenosed dog aorta.

PubMed

Liepsch, D W; Levesque, M; Nerem, R M; Moravec, S T

1988-01-01

Laser-Doppler-velocity measurements were carried out in an elastic 1:1 true-to-scale silicone rubber model of a dog aorta with stenosis. The model was constructed from a cast of a severely stenosed dog aorta (71% of its area). The stenosis in the dog aorta was prepared by wrapping a cotton band around the aorta. This band was tightened until the presence of a thrill or a bruit was felt distal to the band. Twelve weeks later the animal was sacrificed and a cast was prepared from the aorta. From this vascular cast, the cross-sectional area was calculated. Endothelial cell geometry and orientation was studied using computerized analysis to determine the cell area and shape index. An elastic silicone rubber model was prepared from the cast to measure the velocity profiles and to estimate the local wall shear stress. Velocity measurements were done at steady and pulsatile flow using a Newtonian aqueous-glycerol solution and a non-Newtonian blood-like fluid. From those velocity measurements the velocity gradients near the wall were determined and the shear stress calculated. The flow distal to the stenosis separates from the wall at physiological conditions. The endothelial cells are smaller and more elongated in the throat; distal to the stenosis they are larger and rounder. The shape index distribution along the stenosed aorta is correlated with the level of wall shear stress. It is shown that even low changes in the wall shear stress have an influence on the orientation of the endothelial cells.

Large Eddy Simulation of Supercritical CO2 Through Bend Pipes

NASA Astrophysics Data System (ADS)

He, Xiaoliang; Apte, Sourabh; Dogan, Omer

2017-11-01

Supercritical Carbon Dioxide (sCO2) is investigated as working fluid for power generation in thermal solar, fossil energy and nuclear power plants at high pressures. Severe erosion has been observed in the sCO2 test loops, particularly in nozzles, turbine blades and pipe bends. It is hypothesized that complex flow features such as flow separation and property variations may lead to large oscillations in the wall shear stresses and result in material erosion. In this work, large eddy simulations are conducted at different Reynolds numbers (5000, 27,000 and 50,000) to investigate the effect of heat transfer in a 90 degree bend pipe with unit radius of curvature in order to identify the potential causes of the erosion. The simulation is first performed without heat transfer to validate the flow solver against available experimental and computational studies. Mean flow statistics, turbulent kinetic energy, shear stresses and wall force spectra are computed and compared with available experimental data. Formation of counter-rotating vortices, named Dean vortices, are observed. Secondary flow pattern and swirling-switching flow motions are identified and visualized. Effects of heat transfer on these flow phenomena are then investigated by applying a constant heat flux at the wall. DOE Fossil Energy Crosscutting Technology Research Program.

Measurement of terms and parameters in turbulent models

NASA Technical Reports Server (NTRS)

Sandborn, Virgil A.

1989-01-01

Experimental measurements of the mean and turbulent velocity field in a water flow, turn-around-duct is documented. The small radius of curvature duct experiments were made over a range of Reynolds numbers (based on a duct height of 10 cm) from 70,000 to 500,000. For this particular channel, the flow is dominated by the inertia forces. Use of the local bulk velocity to non-dimensionalize the local velocity was found to limit Reynolds number effects to the regions very close to the wall. Only secondary effects on the flow field were observed when the inlet or exit boundary conditions were altered. The flow over the central two-thirds of the channel was two-dimensional. Mean tangetial and radial velocities, streamlines, pressure distributions, surface shear stress; tangential, radial and lateral turbulent velocities and the Reynolds turbulent shear values are tabulated in other reports. It is evident from the experimental study that a complex numerical modeling technique must be developed to predict the flow in the turn-around-duct. The model must be able to predict relaminarization along the inner-convex-wall. It must also allow for the major increase in turbulence produced by the outer-concave-wall.

Injectable Solid Peptide Hydrogel as Cell Carrier: Effects of Shear Flow on Hydrogel and Cell Payload

PubMed Central

Yan, Congqi; Mackay, Michael E.; Czymmek, Kirk; Nagarkar, Radhika P.; Schneider, Joel P.; Pochan, Darrin J.

2012-01-01

β-hairpin peptide-based hydrogels are a class of injectable solid hydrogels that can deliver encapsulated cells or molecular therapies to a target site via syringe or catheter injection as a carrier material. These physical hydrogels can shear-thin and consequently flow as a low-viscosity material under a sufficient shear stress but immediately recover back into a solid upon removal of the stress, allowing them to be injected as preformed gel solids. Hydrogel behavior during flow was studied in a cylindrical capillary geometry that mimicked the actual situation of injection through a syringe needle in order to quantify effects of shear-thin injection delivery on hydrogel flow behavior and encapsulated cell payloads. It was observed that all β-hairpin peptide hydrogels investigated displayed a promising flow profile for injectable cell delivery: a central wide plug flow region where gel material and cell payloads experienced little or no shear rate and a narrow shear zone close to the capillary wall where gel and cells were subject to shear deformation. The width of the plug flow region was found to be weakly dependent on hydrogel rigidity and flow rate. Live-dead assays were performed on encapsulated MG63 cells three hours after injection flow and revealed that shear-thin delivery through the capillary had little impact on cell viability and the spatial distribution of encapsulated cell payloads. These observations help us to fundamentally understand how the gels flow during injection through a thin catheter and how they immediately restore mechanically and morphologically relative to pre-flow, static gels. PMID:22390812

New concepts for Reynolds stress transport equation modeling of inhomogeneous flows

NASA Technical Reports Server (NTRS)

Perot, J. Blair; Moin, Parviz

1993-01-01

The ability to model turbulence near solid walls and other types of boundaries is important in predicting complex engineering flows. Most turbulence modeling has concentrated either on flows which are nearly homogeneous or isotropic, or on turbulent boundary layers. Boundary layer models usually rely very heavily on the presence of mean shear and the production of turbulence due to that mean shear. Most other turbulence models are based on the assumption of quasi-homogeneity. However, there are many situations of engineering interest which do not involve large shear rates and which are not quasi-homogeneous or isotropic. Shear-free turbulent boundary layers are the prototypical example of such flows, with practical situations being separation and reattachment, bluff body flow, high free-stream turbulence, and free surface flows. Although these situations are not as common as the variants of the flat plate turbulent boundary layer, they tend to be critical factors in complex engineering situations. The models developed are intended to extend classical quasi-homogeneous models into regions of large inhomogeneity. These models do not rely on the presence of mean shear or production, but are still applicable when those additional effects are included. Although the focus is on shear-free boundary layers as tests for these models, results for standard shearing boundary layers are also shown.

Calculation of pressure drop in the developmental stages of the medaka fish heart and microvasculature

NASA Astrophysics Data System (ADS)

Chakraborty, Sreyashi; Vlachos, Pavlos

2016-11-01

Peristaltic contraction of the developing medaka fish heart produces temporally and spatially varying pressure drop across the atrioventricular (AV) canal. Blood flowing through the tail vessels experience a slug flow across the developmental stages. We have performed a series of live imaging experiments over 14 days post fertilization (dpf) of the medaka fish egg and cross-correlated the red blood cell (RBC) pattern intensities to obtain the two-dimensional velocity fields. Subsequently we have calculated the pressure field by integrating the pressure gradient in the momentum equation. Our calculations show that the pressure drop across the AV canal increases from 0.8mm Hg during 3dpf to 2.8 mm Hg during 14dpf. We have calculated the time-varying wall shear stress for the blood vessels by assuming a spatially constant velocity magnitude in each vessel. The calculated wall shear stress matches the wall shear stress sensed by human endothelial cells (10-12 dyne/sq. cm). The pressure drop per unit length of the vessel is obtained by doing a control volume analysis of flow in the caudal arteries and veins. The current results can be extended to investigate the effect of the fluid dynamic parameters on the vascular and cardiac morphogenesis.

Supersonic cavity flows over concave and convex walls

NASA Astrophysics Data System (ADS)

Ye, A. Ran; Das, Rajarshi; Setoguchi, Toshiaki; Kim, Heuy Dong

2016-04-01

Supersonic cavity flows are characterized by compression and expansion waves, shear layer, and oscillations inside the cavity. For decades, investigations into cavity flows have been conducted, mostly with flows at zero pressure gradient entering the cavity in straight walls. Since cavity flows on curved walls exert centrifugal force, the features of these flows are likely to differ from those of straight wall flows. The aim of the present work is to study the flow physics of a cavity that is cut out on a curved wall. Steady and unsteady numerical simulations were carried out for supersonic flow through curved channels over the cavity with L/H = 1. A straight channel flow was also analyzed which serves as the base model. The velocity gradient along the width of the channel was observed to increase with increasing the channel curvature for both concave and convex channels. The pressure on the cavity floor increases with the increase in channel curvature for concave channels and decreases for convex channels. Moreover, unsteady flow characteristics are more dependent on channel curvature under supersonic free stream conditions.

Suppressing wall turbulence by means of a transverse traveling wave

PubMed

Du; Karniadakis

2000-05-19

Direct numerical simulations of wall-bounded flow reveal that turbulence production can be suppressed by a transverse traveling wave. Flow visualizations show that the near-wall streaks are eliminated, in contrast to other turbulence-control techniques, leading to a large shear stress reduction. The traveling wave can be induced by a spanwise force that is confined within the viscous sublayer; it has its maximum at the wall and decays exponentially away from it. We demonstrate the application of this approach in salt water, using arrays of electromagnetic tiles that produce the required traveling wave excitation at a high efficiency.

Regeneration of near-wall turbulence structures

NASA Technical Reports Server (NTRS)

Hamilton, James M.; Kim, John J.; Waleffe, Fabian A.

1993-01-01

An examination of the regeneration mechanisms of near-wall turbulence and an attempt to investigate the critical Reynolds number conjecture of Waleffe & Kim is presented. The basis is an extension of the 'minimal channel' approach of Jimenez and Moin which emphasizes the near-wall region and further reduces the complexity of the turbulent flow. Reduction of the flow Reynolds number to the minimum value which will allow turbulence to be sustained has the effect of reducing the ratio of the largest scales to the smallest scales or, equivalently, of causing the near-wall region to fill more of the area between the channel walls. In addition, since each wall may have an active near-wall region, half of the channel is always somewhat redundant. If a plane Couette flow is instead chosen as the base flow, this redundancy is eliminated: the mean shear of a plane Couette flow has a single sign, and at low Reynolds numbers, the two wall regions share a single set of structures. A minimal flow with these modifications possesses, by construction, the strongest constraints which allow sustained turbulence, producing a greatly simplified flow in which the regeneration process can be examined.

Quasi-radial wall jets as a new concept in boundary layer flow control

NASA Astrophysics Data System (ADS)

Javadi, Khodayar; Hajipour, Majid

2018-01-01

This work aims to introduce a novel concept of wall jets wherein the flow is radially injected into a medium through a sector of a cylinder, called quasi-radial (QR) wall jets. The results revealed that fluid dynamics of the QR wall jet flow differs from that of conventional wall jets. Indeed, lateral and normal propagations of a conventional three-dimensional wall jet are via shear stresses. While, lateral propagation of a QR wall jet is due to mean lateral component of the velocity field. Moreover, discharged Arrays of conventional three-dimensional wall jets in quiescent air lead to formation of a combined wall jet at large distant from the nozzles, while QR wall jet immediately spread in lateral direction, meet each other and merge together very quickly in a short distance downstream of the jet nozzles. Furthermore, in discharging the conventional jets into an external flow, there is no strong interaction between them as they are moving parallel. While, in QR wall jets the lateral components of the velocity field strongly interact with boundary layer of the external flow and create strong helical vortices acting as vortex generators.

Intimal cushions and endothelial nuclear elongation around mouse aortic branches and their spatial correspondence with patterns of lipid deposition

PubMed Central

Bond, Andrew R.; Ni, Chih-Wen; Jo, Hanjoong

2010-01-01

Spatial variation in hemodynamic stresses acting on the arterial wall may explain the nonuniform distribution of atherosclerosis. In thoracic aortas of LDL receptor/apolipoprotein E double knockout mice, lesions develop preferentially around the entire circumference of intercostal branch ostia, regardless of age, with the highest prevalence occurring upstream. Additional chevron-shaped lesions occur further upstream of the ostia. This pattern differs from the age-related ones occurring in people and rabbits. In the present study, patterns of near-wall blood flow around intercostal ostia in wild-type mice were estimated from the morphology of endothelial nuclei, which were shown in vitro to elongate in response to elevated shear stress and to align with the flow, and wall structure was assessed from confocal and scanning electron microscopy. A triangular intimal cushion surrounded the upstream part of most ostia. Nuclear length-to-width ratios were lowest over this cushion and highest at the sides of branches, regardless of age. Nuclear orientations were consistent with flow diverging around the branch. The pattern of nuclear morphology differed from the age-related ones observed in rabbits. The intimal cushion and the distribution of shear stress inferred from these observations can partly account for the pattern of lesions observed in knockout mice. Nuclear elongation in nonbranch regions was approximately constant across animals of different size, demonstrating the existence of a mechanism by which endothelial cells compensate for the dependence of mean aortic wall shear stress on body mass. PMID:19933414

Effect of non-Newtonian and pulsatile blood flow on mass transport in the human aorta.

PubMed

Liu, Xiao; Fan, Yubo; Deng, Xiaoyan; Zhan, Fan

2011-04-07

To investigate the effects of both non-Newtonian behavior and the pulsation of blood flow on the distributions of luminal surface LDL concentration and oxygen flux along the wall of the human aorta, we numerically compared a non-Newtonian model with the Newtonian one under both steady flow and in vivo pulsatile flow conditions using a human aorta model constructed from MRI images. The results showed that under steady flow conditions, although the shear thinning non-Newtonian nature of blood could elevate wall shear stress (WSS) in most regions of the aorta, especially areas with low WSS, it had little effect on luminal surface LDL concentration (c(w)) in most regions of the aorta. Nevertheless, it could significantly enhance c(w) in areas with high luminal surface LDL concentration through the shear dependent diffusivity of LDLs. For oxygen transport, the shear thinning non-Newtonian nature of blood could slightly reduce oxygen flux in most regions of the aorta, but this effect became much more apparent in areas with already low oxygen flux. The pulsation of blood flow could significantly reduce c(w) and enhance oxygen flux in these disturbed places. In most other regions of the aorta, the oxygen flux was also significantly higher than that for the steady flow simulation. In conclusion, the shear shining non-Newtonian nature of blood has little effect on LDL and oxygen transport in most regions of the aorta, but in the atherogenic-prone areas where luminal surface LDL concentration is high and oxygen flux is low, its effect is apparent. Similar is for the effect of pulsatile flow on the transport of LDLs. But, the pulsation of blood flow can apparently affect oxygen flux in the aorta, especially in areas with low oxygen flux. Copyright © 2011 Elsevier Ltd. All rights reserved.

Efficient Multiscale Computation with Improved Momentum Flux Coupling via Operator-Splitting and Probabilistic Uncertainty Quantification

DTIC Science & Technology

2016-08-23

Different percentages of clay (10 to 30%) and sand (35 to 55%) have been used to represent various flow concentrations (Table 1). Dynamic viscosity of the... viscosity , was adopted as the wall boundary treatment method. 2.2 Physical Domain The domain consists of a 7.0m long flume, which has an inclination of...the shear stress, μapp is the apparent viscosity , K is the flow consistency index, n is the flow behavior index, and γ is the shear rate, which is

Viscous near-wall flow in a wake of circular cylinder at moderate Reynolds numbers

NASA Astrophysics Data System (ADS)

Okhotnikov, D. I.; Molochnikov, V. M.; Mazo, A. B.; Malyukov, A. V.; Goltsman, A. E.; Saushin, I. I.

2017-11-01

Here we present the results of experimental investigation of a cross flow around a circular cylinder mounted near the wall of a channel with rectangular cross section. The experiments were carried out in the range of Reynolds numbers corresponding to the transition to turbulence in a wake of the cylinder. Flow visualization and SIV-measurements of instantaneous velocity fields were carried out. Evolution of the flow pattern behind the cylinder and formation of the regular vortex structures were analyzed. It is shown that in the case of flow around the cylinder, there is no spiral motion of fluid from the side walls of the channel towards its symmetry plane, typical of the flow around a spanwise rib located on the channel wall. The laminar-turbulent transition in the wake of the cylinder is caused by the shear layer instability.

A time dependent difference theory for sound propagation in ducts with flow. [characteristic of inlet and exhaust ducts of turbofan engines

NASA Technical Reports Server (NTRS)

Baumeister, K. J.

1979-01-01

A time dependent numerical solution of the linearized continuity and momentum equation was developed for sound propagation in a two dimensional straight hard or soft wall duct with a sheared mean flow. The time dependent governing acoustic difference equations and boundary conditions were developed along with a numerical determination of the maximum stable time increments. A harmonic noise source radiating into a quiescent duct was analyzed. This explicit iteration method then calculated stepwise in real time to obtain the transient as well as the steady state solution of the acoustic field. Example calculations were presented for sound propagation in hard and soft wall ducts, with no flow and plug flow. Although the problem with sheared flow was formulated and programmed, sample calculations were not examined. The time dependent finite difference analysis was found to be superior to the steady state finite difference and finite element techniques because of shorter solution times and the elimination of large matrix storage requirements.

Jetting of a shear banding fluid in rectangular ducts

PubMed Central

Salipante, Paul F.; Little, Charles A. E.; Hudson, Steven D.

2017-01-01

Non-Newtonian fluids are susceptible to flow instabilities such as shear banding, in which the fluid may exhibit a markedly discontinuous viscosity at a critical stress. Here we report the characteristics and causes of a jetting flow instability of shear banding wormlike micelle solutions in microfluidic channels with rectangular cross sections over an intermediate volumetric flow regime. Particle-tracking methods are used to measure the three-dimensional flow field in channels of differing aspect ratios, sizes, and wall materials. When jetting occurs, it is self-contained within a portion of the channel where the flow velocity is greater than the surroundings. We observe that the instability forms in channels with aspect ratio greater than 5, and that the location of the high-velocity jet appears to be sensitive to stress localizations. Jetting is not observed in a lower concentration solution without shear banding. Simulations using the Johnson-Segalman viscoelastic model show a qualitatively similar behavior to the experimental observations and indicate that compressive normal stresses in the cross-stream directions support the development of the jetting flow. Our results show that nonuniform flow of shear thinning fluids can develop across the wide dimension in rectangular microfluidic channels, with implications for microfluidic rheometry. PMID:28691108

Effect of wall cooling on the stability of compressible subsonic flows over smooth humps and backward-facing steps

NASA Technical Reports Server (NTRS)

Al-Maaitah, Ayman A.; Nayfeh, Ali, H.; Ragab, Saad A.

1989-01-01

The effect of wall cooling on the two-dimensional linear stability of subsonic flows over two-dimensional surface imperfections is investigated. Results are presented for flows over smooth humps and backward-facing steps with Mach numbers up to 0.8. The results show that, whereas cooling decreases the viscous instability, it increases the shear-layer instability and hence it increases the growth rates in the separation region. The coexistence of more than one instability mechanism makes a certain degree of wall cooling most effective. For the Mach numbers 0.5 and 0.8, the optimum wall temperatures are about 80 pct and 60 pct of the adiabatic wall temperature, respectively. Increasing the Mach number decreases the effectiveness of cooling slightly and reduces the optimum wall temperature.

Numerical investigation of an internal layer in turbulent flow over a curved hill

NASA Technical Reports Server (NTRS)

Kim, S-W.

1989-01-01

The development of an internal layer in a turbulent boundary layer flow over a curved hill is investigated numerically. The turbulence field of the boundary layer flow over the curved hill is compared with that of a turbulent flow over a symmetric airfoil (which has the same geometry as the curved hill except that the leading and trailing edge plates were removed) to study the influence of the strongly curved surface on the turbulence field. The turbulent flow equations are solved by a control-volume based finite difference method. The turbulence is described by a multiple-time-scale turbulence model supplemented with a near-wall turbulence model. Computational results for the mean flow field (pressure distributions on the walls, wall shearing stresses and mean velocity profiles), the turbulence structure (Reynolds stress and turbulent kinetic energy profiles), and the integral parameters (displacement and momentum thicknesses) compared favorably with the measured data. Computational results show that the internal layer is a strong turbulence field which is developed beneath the external boundary layer and is located very close to the wall. Development of the internal layer was more obviously observed in the Reynolds stress profiles and in the turbulent kinetic energy profiles than in the mean velocity profiles. In this regard, the internal layers is significantly different from wall-bounded simple shear layers in which the mean velocity profile characterizes the boundary layer most distinguishably. Development of such an internal layer, characterized by an intense turbulence field, is attributed to the enormous mean flow strain rate caused by the streamline curvature and the strong pressure gradient. In the turbulent flow over the curved hill, the internal layer begin to form near the forward corner of the hill, merges with the external boundary layer, and develops into a new fully turbulent boundary layer as the fluid flows in the downstream direction. For the flow over the symmetric airfoil, the boundary layer began to form from almost the same location as that of the curved hill, grew in its strength, and formed a fully turbulent boundary layer from mid-part of the airfoil and in the downstream region. Computational results also show that the detailed turbulence structure in the region very close to the wall of the curved hill is almost the same as that of the airfoil in most of the curved regions except near the leading edge. Thus the internal layer of the curved hill and the boundary layer of the airfoil were also almost the same. Development of the wall shearing stress and separation of the boundary layer at the rear end of the curved hill mostly depends on the internal layer and is only slightly influenced by the external boundary layer flow.

Reynolds number and roughness effects on turbulent stresses in sandpaper roughness boundary layers

NASA Astrophysics Data System (ADS)

Morrill-Winter, C.; Squire, D. T.; Klewicki, J. C.; Hutchins, N.; Schultz, M. P.; Marusic, I.

2017-05-01

Multicomponent turbulence measurements in rough-wall boundary layers are presented and compared to smooth-wall data over a large friction Reynolds number range (δ+). The rough-wall experiments used the same continuous sandpaper sheet as in the study of Squire et al. [J. Fluid Mech. 795, 210 (2016), 10.1017/jfm.2016.196]. To the authors' knowledge, the present measurements are unique in that they cover nearly an order of magnitude in Reynolds number (δ+≃2800 -17 400 ), while spanning the transitionally to fully rough regimes (equivalent sand-grain-roughness range, ks+≃37 -98 ), and in doing so also maintain very good spatial resolution. Distinct from previous studies, the inner-normalized wall-normal velocity variances, w2¯, exhibit clear dependencies on both ks+ and δ+ well into the wake region of the boundary layer, and only for fully rough flows does the outer portion of the profile agree with that in a comparable δ+ smooth-wall flow. Consistent with the mean dynamical constraints, the inner-normalized Reynolds shear stress profiles in the rough-wall flows are qualitatively similar to their smooth-wall counterparts. Quantitatively, however, at matched Reynolds numbers the peaks in the rough-wall Reynolds shear stress profiles are uniformly located at greater inner-normalized wall-normal positions. The Reynolds stress correlation coefficient, Ru w, is also greater in rough-wall flows at a matched Reynolds number. As in smooth-wall flows, Ru w decreases with Reynolds number, but at different rates depending on the roughness condition. Despite the clear variations in the Ru w profiles with roughness, inertial layer u , w cospectra evidence invariance with ks+ when normalized with the distance from the wall. Comparison of the normalized contributions to the Reynolds stress from the second quadrant (Q2) and fourth quadrant (Q4) exhibit noticeable differences between the smooth- and rough-wall flows. The overall time fraction spent in each quadrant is, however, shown to be nearly fixed for all of the flow conditions investigated. The data indicate that at fixed δ+ both Q2 and Q4 events exhibit a sensitivity to ks+. The present results are discussed relative to the combined influences of roughness and Reynolds number on the scaling behaviors of boundary layers.

Reynolds-Stress and Triple-Product Models Applied to a Flow with Rotation and Curvature

NASA Technical Reports Server (NTRS)

Olsen, Michael E.

2016-01-01

Turbulence models, with increasing complexity, up to triple product terms, are applied to the flow in a rotating pipe. The rotating pipe is a challenging case for turbulence models as it contains significant rotational and curvature effects. The flow field starts with the classic fully developed pipe flow, with a stationary pipe wall. This well defined condition is then subjected to a section of pipe with a rotating wall. The rotating wall introduces a second velocity scale, and creates Reynolds shear stresses in the radial-circumferential and circumferential-axial planes. Furthermore, the wall rotation introduces a flow stabilization, and actually reduces the turbulent kinetic energy as the flow moves along the rotating wall section. It is shown in the present work that the Reynolds stress models are capable of predicting significant reduction in the turbulent kinetic energy, but triple product improves the predictions of the centerline turbulent kinetic energy, which is governed by convection, dissipation and transport terms, as the production terms vanish on the pipe axis.

Self similarity of two point correlations in wall bounded turbulent flows

NASA Technical Reports Server (NTRS)

Hunt, J. C. R.; Moin, P.; Moser, R. D.; Spalart, P. R.

1987-01-01

The structure of turbulence at a height y from a wall is affected by the local mean shear at y, by the direct effect of the wall on the eddies, and by the action of other eddies close to or far from the wall. Some researchers believe that a single one of these mechanisms is dominant, while others believe that these effects have to be considered together. It is important to understand the relative importance of these effects in order to develop closure models, for example for the dissipation or for the Reynolds stress equation, and to understand the eddy structure of cross correlation functions and other measures. The specific objective was to examine the two point correlation, R sub vv, of the normal velocity component v near the wall in a turbulent channel flow and in a turbulent boundary layer. The preliminary results show that even in the inhomogeneous turbulent boundary layer, the two-point correlation function may have self similar forms. The results also show that the effects of shear and of blocking are equally important in the form of correlation functions for spacing normal to the wall. But for spanwise spacing, it was found that the eddy structure is quire different in these near flows. So any theory for turbulent structure must take both these effects into account.

The effect of inlet boundary conditions in image-based CFD modeling of aortic flow

NASA Astrophysics Data System (ADS)

Madhavan, Sudharsan; Kemmerling, Erica Cherry

2016-11-01

CFD of cardiovascular flow is a growing and useful field, but simulations are subject to a number of sources of uncertainty which must be quantified. Our work focuses on the uncertainty introduced by the selection of inlet boundary conditions in an image-based, patient-specific model of the aorta. Specifically, we examined the differences between plug flow, fully developed parabolic flow, linear shear flows, skewed parabolic flow profiles, and Womersley flow. Only the shape of the inlet velocity profile was varied-all other parameters were held constant between simulations, including the physiologically realistic inlet flow rate waveform and outlet flow resistance. We found that flow solutions with different inlet conditions did not exhibit significant differences beyond 1 . 75 inlet diameters from the aortic root. Time averaged wall shear stress (TAWSS) was also calculated. The linear shear velocity boundary condition solution exhibited the highest spatially averaged TAWSS, about 2 . 5 % higher than the fully developed parabolic velocity boundary condition, which had the lowest spatially averaged TAWSS.

Behavior of Rapidly Sheared Bubble Suspensions

NASA Technical Reports Server (NTRS)

Sangani, A. S.; Kushch, V. I.; Hoffmann, M.; Nahra, H.; Koch, D. L.; Tsang, Y.

2002-01-01

An experiment to be carried out aboard the International Space Station is described. A suspension consisting of millimeter-sized bubbles in water containing some dissolved salt, which prevents bubbles from coalescing, will be sheared in a Couette cylindrical cell. Rotation of the outer cylinder will produce centrifugal force which will tend to accumulate the bubbles near the inner wall. The shearing will enhance collisions among bubbles creating thereby bubble phase pressure that will resist the tendency of the bubbles to accumulate near the inner wall. The bubble volume fraction and velocity profiles will be measured and compared with the theoretical predictions. Ground-based research on measurement of bubble phase properties and flow in vertical channel are described.

Theoretical and Experimental Studies of the Transonic Flow Field and Associated Boundary Conditions near a Longitudinally-Slotted Wind-Tunnel Wall. Ph.D. Thesis

NASA Technical Reports Server (NTRS)

Everhart, Joel Lee

1988-01-01

A theoretical examination of the slotted-wall flow field is conducted to determine the appropriate wall pressure drop (or boundary condition) equation. This analysis improves the understanding of the fluid physics of these types of flow fields and helps in evaluating the uncertainties and limitations existing in previous mathematical developments. It is shown that the resulting slotted-wall boundary condition contains contributions from the airfoil-induced streamline curvature and the non-linear, quadratic, slot crossflow in addition to an often neglected linear term which results from viscous shearing in the slot. Existing and newly acquired experimental data are examined in the light of this formulation and theoretical developments.

Laminar-to-turbulence and relaminarization zones detection by simulation of low Reynolds number turbulent blood flow in large stenosed arteries.

PubMed

Tabe, Reza; Ghalichi, Farzan; Hossainpour, Siamak; Ghasemzadeh, Kamran

2016-08-12

Laminar, turbulent, transitional, or combine areas of all three types of viscous flow can occur downstream of a stenosis depending upon the Reynolds number and constriction shape parameter. Neither laminar flow solver nor turbulent models for instance the k-ω (k-omega), k-ε (k-epsilon), RANS or LES are opportune for this type of flow. In the present study attention has been focused vigorously on the effect of the constriction in the flow field with a unique way. It means that the laminar solver was employed from entry up to the beginning of the turbulent shear flow. The turbulent model (k-ω SST Transitional Flows) was utilized from starting of turbulence to relaminarization zone while the laminar model was applied again with onset of the relaminarization district. Stenotic flows, with 50 and 75% cross-sectional area, were simulated at Reynolds numbers range from 500 to 2000 employing FLUENT (v6.3.17). The flow was considered to be steady, axisymmetric, and incompressible. Achieving results were reported as axial velocity, disturbance velocity, wall shear stress and the outcomes were compared with previously experimental and CFD computations. The analogy of axial velocity profiles shows that they are in acceptable compliance with the empirical data. As well as disturbance velocity and wall shear stresses anticipated by this new approach, part by part simulation, are reasonably valid with the acceptable experimental studies.

Investigation of hemodynamics in the development of dissecting aneurysm within patient-specific dissecting aneurismal aortas using computational fluid dynamics (CFD) simulations.

PubMed

Tse, Kwong Ming; Chiu, Peixuan; Lee, Heow Pueh; Ho, Pei

2011-03-15

Aortic dissecting aneurysm is one of the most catastrophic cardiovascular emergencies that carries high mortality. It was pointed out from clinical observations that the aneurysm development is likely to be related to the hemodynamics condition of the dissected aorta. In order to gain more insight on the formation and progression of dissecting aneurysm, hemodynamic parameters including flow pattern, velocity distribution, aortic wall pressure and shear stress, which are difficult to measure in vivo, are evaluated using numerical simulations. Pulsatile blood flow in patient-specific dissecting aneurismal aortas before and after the formation of lumenal aneurysm (pre-aneurysm and post-aneurysm) is investigated by computational fluid dynamics (CFD) simulations. Realistic time-dependent boundary conditions are prescribed at various arteries of the complete aorta models. This study suggests the helical development of false lumen around true lumen may be related to the helical nature of hemodynamic flow in aorta. Narrowing of the aorta is responsible for the massive recirculation in the poststenosis region in the lumenal aneurysm development. High pressure difference of 0.21 kPa between true and false lumens in the pre-aneurismal aorta infers the possible lumenal aneurysm site in the descending aorta. It is also found that relatively high time-averaged wall shear stress (in the range of 4-8 kPa) may be associated with tear initiation and propagation. CFD modeling assists in medical planning by providing blood flow patterns, wall pressure and wall shear stress. This helps to understand various phenomena in the development of dissecting aneurysm. Copyright © 2011 Elsevier Ltd. All rights reserved.

A Hybrid Windkessel Model of Blood Flow in Arterial Tree Using Velocity Profile Method

NASA Astrophysics Data System (ADS)

Aboelkassem, Yasser; Virag, Zdravko

2016-11-01

For the study of pulsatile blood flow in the arterial system, we derived a coupled Windkessel-Womersley mathematical model. Initially, a 6-elements Windkessel model is proposed to describe the hemodynamics transport in terms of constant resistance, inductance and capacitance. This model can be seen as a two compartment model, in which the compartments are connected by a rigid pipe, modeled by one inductor and resistor. The first viscoelastic compartment models proximal part of the aorta, the second elastic compartment represents the rest of the arterial tree and aorta can be seen as the connection pipe. Although the proposed 6-elements lumped model was able to accurately reconstruct the aortic pressure, it can't be used to predict the axial velocity distribution in the aorta and the wall shear stress and consequently, proper time varying pressure drop. We then modified this lumped model by replacing the connection pipe circuit elements with a vessel having a radius R and a length L. The pulsatile flow motions in the vessel are resolved instantaneously along with the Windkessel like model enable not only accurate prediction of the aortic pressure but also wall shear stress and frictional pressure drop. The proposed hybrid model has been validated using several in-vivo aortic pressure and flow rate data acquired from different species such as, humans, dogs and pigs. The method accurately predicts the time variation of wall shear stress and frictional pressure drop. Institute for Computational Medicine, Dept. Biomedical Engineering.

Application of kinematic vorticity and gold mineralization for the wall rock alterations of shear zone at Dungash gold mining, Central Eastern Desert, Egypt

NASA Astrophysics Data System (ADS)

Kassem, Osama M. K.; Abd El Rahim, Said H.; El Nashar, EL Said R.; AL Kahtany, Kaled M.

2016-11-01

The use of porphyroclasts rotating in a flowing matrix to estimate mean kinematic vorticity number (Wm) is important for quantifying the relative contributions of pure and simple shear in wall rocks alterations of shear zone at Dungash gold mine. Furthermore, it shows the relationship between the gold mineralization and deformation and also detects the orientation of rigid objects during progressive deformation. The Dungash gold mine area is situated in an EW-trending quartz vein along a shear zone in metavolcanic and metasedimentary host rocks in the Eastern Desert of Egypt. These rocks are associated with the major geologic structures which are attributed to various deformational stages of the Neoproterozoic basement rocks. We conclude that finite strain in the deformed rocks is of the same order of magnitude for all units of metavolcano-sedimentary rocks. The kinematic vorticity number for the metavolcanic and metasedimentary samples in the Dungash area range from 0.80 to 0.92, and together with the strain data suggest deviations from simple shear. It is concluded that nappe stacking occurred early during the underthrusting event probably by brittle imbrication and that ductile strain was superimposed on the nappe structure during thrusting. Furthermore, we conclude that disseminated mineralization, chloritization, carbonatization and silicification of the wall rocks are associated with fluids migrating along shearing, fracturing and foliation of the metamorphosed wall rocks.

Distinct molecular and cellular contributions to stabilizing selectin-mediated rolling under flow

PubMed Central

Yago, Tadayuki; Leppänen, Anne; Qiu, Haiying; Marcus, Warren D.; Nollert, Matthias U.; Zhu, Cheng; Cummings, Richard D.; McEver, Rodger P.

2002-01-01

Leukocytes roll on selectins at nearly constant velocities over a wide range of wall shear stresses. Ligand-coupled microspheres roll faster on selectins and detach quickly as wall shear stress is increased. To examine whether the superior performance of leukocytes reflects molecular features of native ligands or cellular properties that favor selectin-mediated rolling, we coupled structurally defined selectin ligands to microspheres or K562 cells and compared their rolling on P-selectin. Microspheres bearing soluble P-selectin glycoprotein ligand (sPSGL)-1 or 2-glycosulfopeptide (GSP)-6, a GSP modeled after the NH2-terminal P-selectin–binding region of PSGL-1, rolled equivalently but unstably on P-selectin. K562 cells displaying randomly coupled 2-GSP-6 also rolled unstably. In contrast, K562 cells bearing randomly coupled sPSGL-1 or 2-GSP-6 targeted to a membrane-distal region of the presumed glycocalyx rolled more like leukocytes: rolling steps were more uniform and shear resistant, and rolling velocities tended to plateau as wall shear stress was increased. K562 cells treated with paraformaldehyde or methyl-β-cyclodextrin before ligand coupling were less deformable and rolled unstably like microspheres. Cells treated with cytochalasin D were more deformable, further resisted detachment, and rolled slowly despite increases in wall shear stress. Thus, stable, shear-resistant rolling requires cellular properties that optimize selectin–ligand interactions. PMID:12177042

Skin friction measurements by laser interferometry in swept shock wave/turbulent boundary-layer interactions

NASA Technical Reports Server (NTRS)

Kim, Kwang-Soo; Settles, Gary S.

1988-01-01

The laser interferometric skin friction meter was used to measure wall shear stress distributions in two interactions of fin-generated swept shock waves with turbulent boundary layers. The basic research configuration was an unswept sharp-leading-edge fin of variable angle mounted on a flatplate. The results indicate that such measurements are practical in high-speed interacting flows, and that a repeatability of + or - 6 percent or better is possible. Marked increases in wall shear were observed in both swept interactions tested.

Estimation of Blood Flow Rates in Large Microvascular Networks

PubMed Central

Fry, Brendan C.; Lee, Jack; Smith, Nicolas P.; Secomb, Timothy W.

2012-01-01

Objective Recent methods for imaging microvascular structures provide geometrical data on networks containing thousands of segments. Prediction of functional properties, such as solute transport, requires information on blood flow rates also, but experimental measurement of many individual flows is difficult. Here, a method is presented for estimating flow rates in a microvascular network based on incomplete information on the flows in the boundary segments that feed and drain the network. Methods With incomplete boundary data, the equations governing blood flow form an underdetermined linear system. An algorithm was developed that uses independent information about the distribution of wall shear stresses and pressures in microvessels to resolve this indeterminacy, by minimizing the deviation of pressures and wall shear stresses from target values. Results The algorithm was tested using previously obtained experimental flow data from four microvascular networks in the rat mesentery. With two or three prescribed boundary conditions, predicted flows showed relatively small errors in most segments and fewer than 10% incorrect flow directions on average. Conclusions The proposed method can be used to estimate flow rates in microvascular networks, based on incomplete boundary data and provides a basis for deducing functional properties of microvessel networks. PMID:22506980

Mathematical model of carotid artery for stent placement

NASA Astrophysics Data System (ADS)

Rahman, Tengku Husna Tengku Abdul; Din, Ummul Khair Salma; Ahmad, Rokiah @ Rozita

2016-11-01

The carotid artery stenting is one of the methods used to reduce the effect of artherosclerosis which caused by the thickening of the artery wall. In most of the studies, the measure of wall elasticity, shear stress and the blood pressure through the blood flow were considered. The aim of this study is to determine the position to place the stent inside the carotid artery. A mathematical model is reconstructed to determine the suitable location of the stent in the carotid artery. Throughout the study, differences in fluid flow between a normal carotid artery wall and stenosed carotid artery wall are investigated. Since the existence of the stenosis provides a resistance in the flow, it is important to identify the right position to place the stent. The stent will be placed in the position where stenosis exists to ease the blood to flow normally. Later after the stent placement, the blood flow normally through the blood vessel.

Thermal control of electroosmotic flow in a microchannel through temperature-dependent properties.

PubMed

Kwak, Ho Sang; Kim, Hyoungsoo; Hyun, Jae Min; Song, Tae-Ho

2009-07-01

A numerical investigation is conducted on the electroosmotic flow and associated heat transfer in a two-dimensional microchannel. The objective of this study is to explore a new conceptual idea that is control of an electroosmotic flow by using a thermal field effect through the temperature-dependent physical properties. Two exemplary problems are examined: a flow in a microchannel with a constant vertical temperature difference between two horizontal walls and a flow in a microchannel with the wall temperatures varying horizontally in a sinusoidal manner. The results of numerical computations showed that a proper control of thermal field may be a viable means to manipulate various non-plug-like flow patterns. A constant vertical temperature difference across the channel produces a shear flow. The horizontally-varying thermal condition results in spatial variation of physical properties to generate fluctuating flow patterns. The temperature variation at the wall with alternating vertical temperature gradient induces a wavy flow.

Population splitting of rodlike swimmers in Couette flow.

PubMed

Nili, Hossein; Kheyri, Masoud; Abazari, Javad; Fahimniya, Ali; Naji, Ali

2017-06-28

We present a quantitative analysis on the response of a dilute active suspension of self-propelled rods (swimmers) in a planar channel subjected to an imposed shear flow. To best capture the salient features of the shear-induced effects, we consider the case of an imposed Couette flow, providing a constant shear rate across the channel. We argue that the steady-state behavior of swimmers can be understood in the light of a population splitting phenomenon, occurring as the shear rate exceeds a certain threshold, initiating the reversal of the swimming direction for a finite fraction of swimmers from down- to upstream or vice versa, depending on the swimmer position within the channel. Swimmers thus split into two distinct, statistically significant and oppositely swimming majority and minority populations. The onset of population splitting translates into a transition from a self-propulsion-dominated regime to a shear-dominated regime, corresponding to a unimodal-to-bimodal change in the probability distribution function of the swimmer orientation. We present a phase diagram in terms of the swim and flow Péclet numbers showing the separation of these two regimes by a discontinuous transition line. Our results shed further light on the behavior of swimmers in a shear flow and provide an explanation for the previously reported non-monotonic behavior of the mean, near-wall, parallel-to-flow orientation of swimmers with increasing shear strength.

Time-dependent particle migration and margination in the pressure-driven channel flow of blood

NASA Astrophysics Data System (ADS)

Qi, Qin M.; Shaqfeh, Eric S. G.

2018-03-01

We present a theory to describe the time evolution of the red blood cell (RBC) and platelet concentration distributions in pressure-driven flow through a straight channel. This model is based on our previous theory for the steady-state distributions [Qi and Shaqfeh, Phys. Rev. Fluids 2, 093102 (2017), 10.1103/PhysRevFluids.2.093102] and captures the flow-induced nonuniformity of the concentrations of RBCs and platelets in the cross-flow direction. Starting with a uniform concentration, RBCs migrate away from the channel walls due to a shear-induced lift force and eventually reach steady state due to shear-induced diffusion, i.e., hydrodynamic "collisions" with other RBCs. On the other hand, platelets exit the cell-laden region due to RBC-platelet interactions and enter the cell-free layer, resulting in margination. To validate the theory, we also perform boundary integral simulations of blood flow in microchannels and directly compare various measureables between theory and simulation. The timescales associated with RBC migration and platelet margination are discussed in the context of the simulation and theory, and their importance in the function of microfluidic devices as well as the vascular network are elucidated. Due to the varying shear rate in pressure-driven flow and the wall-induced RBC lift, we report a separation of timescales for the transport in the near-wall region and in the bulk region. We also relate the transient problem to the axial variation of migration and margination, and we demonstrate how the relevant timescales can be used to predict corresponding entrance lengths. Our theory can serve as a fast and convenient alternative to large-scale simulations of these phenomena.

Effect of short-chain branching on interfacial polymer structure and dynamics under shear flow.

PubMed

Jeong, Sohdam; Kim, Jun Mo; Cho, Soowon; Baig, Chunggi

2017-11-22

We present a detailed analysis on the effect of short-chain branches on the structure and dynamics of interfacial chains using atomistic nonequilibrium molecular dynamics simulations of confined polyethylene melts in a wide range of shear rates. The intrinsically fast random motions of the short branches constantly disturb the overall chain conformation, leading to a more compact and less deformed chain structure of the short-chain branched (SCB) polymer against the imposed flow field in comparison with the corresponding linear polymer. Moreover, such highly mobile short branches along the backbone of the SCB polymer lead to relatively weaker out-of-plane wagging dynamics of interfacial chains, with highly curvy backbone structures in the intermediate flow regime. In conjunction with the contribution of short branches (as opposed to that of the backbone) to the total interfacial friction between the chains and the wall, the SCB polymer shows a nearly constant behavior in the degree of slip (d s ) with respect to shear rate in the weak-to-intermediate flow regimes. On the contrary, in the strong flow regime where irregular chain rotation and tumbling dynamics occur via intensive dynamical collisions between interfacial chains and the wall, an enhancement effect on the chain detachment from the wall, caused by short branches, leads to a steeper increase in d s for the SCB polymer than for the linear polymer. Remarkably, the SCB chains at the interface exhibit two distinct types of rolling mechanisms along the backbone, with a half-dumbbell mesoscopic structure at strong flow fields, in addition to the typical hairpin-like tumbling behavior displayed by the linear chains.

A computational study of the respiratory airflow characteristics in normal and obstructed human airways.

PubMed

Sul, Bora; Wallqvist, Anders; Morris, Michael J; Reifman, Jaques; Rakesh, Vineet

2014-09-01

Obstructive lung diseases in the lower airways are a leading health concern worldwide. To improve our understanding of the pathophysiology of lower airways, we studied airflow characteristics in the lung between the 8th and the 14th generations using a three-dimensional computational fluid dynamics model, where we compared normal and obstructed airways for a range of breathing conditions. We employed a novel technique based on computing the Pearson׳s correlation coefficient to quantitatively characterize the differences in airflow patterns between the normal and obstructed airways. We found that the airflow patterns demonstrated clear differences between normal and diseased conditions for high expiratory flow rates (>2300ml/s), but not for inspiratory flow rates. Moreover, airflow patterns subjected to filtering demonstrated higher sensitivity than airway resistance for differentiating normal and diseased conditions. Further, we showed that wall shear stresses were not only dependent on breathing rates, but also on the distribution of the obstructed sites in the lung: for the same degree of obstruction and breathing rate, we observed as much as two-fold differences in shear stresses. In contrast to previous studies that suggest increased wall shear stress due to obstructions as a possible damage mechanism for small airways, our model demonstrated that for flow rates corresponding to heavy activities, the wall shear stress in both normal and obstructed airways was <0.3Pa, which is within the physiological limit needed to promote respiratory defense mechanisms. In summary, our model enables the study of airflow characteristics that may be impractical to assess experimentally. Published by Elsevier Ltd.

Compressibility Considerations for kappa-omega Turbulence Models in Hypersonic Boundary Layer Applications

NASA Technical Reports Server (NTRS)

Rumsey, C. L.

2009-01-01

The ability of kappa-omega models to predict compressible turbulent skin friction in hypersonic boundary layers is investigated. Although uncorrected two-equation models can agree well with correlations for hot-wall cases, they tend to perform progressively worse - particularly for cold walls - as the Mach number is increased in the hypersonic regime. Simple algebraic models such as Baldwin-Lomax perform better compared to experiments and correlations in these circumstances. Many of the compressibility corrections described in the literature are summarized here. These include corrections that have only a small influence for kappa-omega models, or that apply only in specific circumstances. The most widely-used general corrections were designed for use with jet or mixing-layer free shear flows. A less well-known dilatation-dissipation correction intended for boundary layer flows is also tested, and is shown to agree reasonably well with the Baldwin-Lomax model at cold-wall conditions. It exhibits a less dramatic influence than the free shear type of correction. There is clearly a need for improved understanding and better overall physical modeling for turbulence models applied to hypersonic boundary layer flows.

Self-sustaining processes at all scales in wall-bounded turbulent shear flows

PubMed Central

Hwang, Yongyun

2017-01-01

We collect and discuss the results of our recent studies which show evidence of the existence of a whole family of self-sustaining motions in wall-bounded turbulent shear flows with scales ranging from those of buffer-layer streaks to those of large-scale and very-large-scale motions in the outer layer. The statistical and dynamical features of this family of self-sustaining motions, which are associated with streaks and quasi-streamwise vortices, are consistent with those of Townsend’s attached eddies. Motions at each relevant scale are able to sustain themselves in the absence of forcing from larger- or smaller-scale motions by extracting energy from the mean flow via a coherent lift-up effect. The coherent self-sustaining process is embedded in a set of invariant solutions of the filtered Navier–Stokes equations which take into full account the Reynolds stresses associated with the residual smaller-scale motions. This article is part of the themed issue ‘Toward the development of high-fidelity models of wall turbulence at large Reynolds number’. PMID:28167581

Self-sustaining processes at all scales in wall-bounded turbulent shear flows.

PubMed

Cossu, Carlo; Hwang, Yongyun

2017-03-13

We collect and discuss the results of our recent studies which show evidence of the existence of a whole family of self-sustaining motions in wall-bounded turbulent shear flows with scales ranging from those of buffer-layer streaks to those of large-scale and very-large-scale motions in the outer layer. The statistical and dynamical features of this family of self-sustaining motions, which are associated with streaks and quasi-streamwise vortices, are consistent with those of Townsend's attached eddies. Motions at each relevant scale are able to sustain themselves in the absence of forcing from larger- or smaller-scale motions by extracting energy from the mean flow via a coherent lift-up effect. The coherent self-sustaining process is embedded in a set of invariant solutions of the filtered Navier-Stokes equations which take into full account the Reynolds stresses associated with the residual smaller-scale motions.This article is part of the themed issue 'Toward the development of high-fidelity models of wall turbulence at large Reynolds number'. © 2017 The Author(s).

Self-sustaining processes at all scales in wall-bounded turbulent shear flows

NASA Astrophysics Data System (ADS)

Cossu, Carlo; Hwang, Yongyun

2017-03-01

We collect and discuss the results of our recent studies which show evidence of the existence of a whole family of self-sustaining motions in wall-bounded turbulent shear flows with scales ranging from those of buffer-layer streaks to those of large-scale and very-large-scale motions in the outer layer. The statistical and dynamical features of this family of self-sustaining motions, which are associated with streaks and quasi-streamwise vortices, are consistent with those of Townsend's attached eddies. Motions at each relevant scale are able to sustain themselves in the absence of forcing from larger- or smaller-scale motions by extracting energy from the mean flow via a coherent lift-up effect. The coherent self-sustaining process is embedded in a set of invariant solutions of the filtered Navier-Stokes equations which take into full account the Reynolds stresses associated with the residual smaller-scale motions.

Mechanical erosion of xenoliths by magmatic shear flow

NASA Astrophysics Data System (ADS)

Del Gaudio, Piero; Ventura, Guido

2008-05-01

We focus on the role of mechanical erosion by magmatic shear flow in the formation of xenoliths occurring in lava flows. The process is analyzed by combining the physics of fragmentation and erosion to the concept of rock mass. The conditions for the country rock fragmentation are analyzed as a function of the magma viscosity, strain rate and tensile strength of the rock mass. In reservoirs, mechanical processes play a subordinate role and thermal erosion processes prevail. In conduits, intermediate and silicic magmas may erode and, eventually, fragment good to poor quality country rock masses. Basalts may erode poor quality country rocks. A crystal-rich magma has more chance to break up the conduit walls with respect to a vesiculated melt. The variety of xenoliths of a lava reflects a set of wall-rocks with similar mechanical properties and may not mirror the stratigraphy of the substratum of a volcanic area.

Development of buried wire gages for measurement of wall shear stress in Blastane experiments

NASA Technical Reports Server (NTRS)

Murthy, S. V.; Steinle, F. W.

1986-01-01

Buried Wire Gages operated from a Constant Temperature Anemometer System are among the special types of instrumentation to be used in the Boundary Layer Apparatus for Subsonic and Transonic flow Affected by Noise Environment (BLASTANE). These Gages are of a new type and need to be adapted for specific applications. Methods were developed to fabricate Gage inserts and mount those in the BLASTANE Instrumentation Plugs. A large number of Gages were prepared and operated from a Constant Temperature Anemometer System to derive some of the calibration constants for application to fluid-flow wall shear-stress measurements. The final stage of the calibration was defined, but could not be accomplished because of non-availability of a suitable flow simulating apparatus. This report provides a description of the Buried Wire Gage technique, an explanation of the method evolved for making proper Gages and the calibration constants, namely Temperature Coefficient of Resistance and Conduction Loss Factor.

Measurement and prediction of flow through a replica segment of a mildly atherosclerotic coronary artery of man

NASA Technical Reports Server (NTRS)

Back, L. H.; Radbill, J. R.; Cho, Y. I.; Crawford, D. W.

1986-01-01

Pressure distributions were measured along a hollow vascular axisymmetric replica of a segment of the left circumflex coronary artery of man with mildly atherosclerotic diffuse disease. A large range of physiological Reynolds numbers from about 60 to 500, including hyperemic response, was spanned in the flows investigation using a fluid simulating blood kinematic viscosity. Predicted pressure distributions from the numerical solution of the Navier-Stokes equations were similar in trend and magnitude to the measurements. Large variations in the predicted velocity profiles occurred along the lumen. The influence of the smaller scale multiple flow obstacles along the wall (lesion variations) led to sharp spikes in the predicted wall shear stresses. Reynolds number similarity was discussed, and estimates of what time averaged in vivo pressure drop and shear stress might be were given for a vessel segment.

Effects of the finite particle size in turbulent wall-bounded flows of dense suspensions

NASA Astrophysics Data System (ADS)

Costa, Pedro; Picano, Francesco; Brandt, Luca; Breugem, Wim-Paul

2018-05-01

We use interface-resolved simulations to study finite-size effects in turbulent channel flow of neutrally-buoyant spheres. Two cases with particle sizes differing by a factor of 2, at the same solid volume fraction of 20% and bulk Reynolds number are considered. These are complemented with two reference single-phase flows: the unladen case, and the flow of a Newtonian fluid with the effective suspension viscosity of the same mixture in the laminar regime. As recently highlighted in Costa et al. (PRL 117, 134501), a particle-wall layer is responsible for deviations of the statistics from what is observed in the continuum limit where the suspension is modeled as a Newtonian fluid with an effective viscosity. Here we investigate the fluid and particle dynamics in this layer and in the bulk. In the particle-wall layer, the near wall inhomogeneity has an influence on the suspension micro-structure over a distance proportional to the particle size. In this layer, particles have a significant (apparent) slip velocity that is reflected in the distribution of wall shear stresses. This is characterized by extreme events (both much higher and much lower than the mean). Based on these observations we provide a scaling for the particle-to-fluid apparent slip velocity as a function of the flow parameters. We also extend the flow scaling laws in to second-order Eulerian statistics in the homogeneous suspension region away from the wall. Finite-size effects in the bulk of the channel become important for larger particles, while negligible for lower-order statistics and smaller particles. Finally, we study the particle dynamics along the wall-normal direction. Our results suggest that 1-point dispersion is dominated by particle-turbulence (and not particle-particle) interactions, while differences in 2-point dispersion and collisional dynamics are consistent with a picture of shear-driven interactions.

Temporal and spatial intermittencies within Newtonian turbulence

NASA Astrophysics Data System (ADS)

Kushwaha, Anubhav; Graham, Michael

2015-11-01

Direct numerical simulations of a pressure driven turbulent flow are performed in a large rectangular channel. Intermittent high- and low-drag regimes within turbulence that have earlier been found to exist temporally in minimal channels have been observed both spatially and temporally in full-size turbulent flows. These intermittent regimes, namely, ''active'' and ''hibernating'' turbulence, display very different structural and statistical features. We adopt a very simple sampling technique to identify these intermittent intervals, both temporally and spatially, and present differences between them in terms of simple quantities like mean-velocity, wall-shear stress and flow structures. By conditionally sampling of the low wall-shear stress events in particular, we show that the Maximum Drag Reduction (MDR) velocity profile, that occurs in viscoelastic flows, can also be approached in a Newtonian-fluid flow in the absence of any additives. This suggests that the properties of polymer drag reduction are inherent to all flows and their occurrence is just enhanced by the addition of polymers. We also show how the intermittencies within turbulence vary with Reynolds number. The work was supported by AFOSR grant FA9550-15-1-0062.

Laminar, turbulent, and inertial shear-thickening regimes in channel flow of neutrally buoyant particle suspensions.

PubMed

Lashgari, Iman; Picano, Francesco; Breugem, Wim-Paul; Brandt, Luca

2014-12-19

The aim of this Letter is to characterize the flow regimes of suspensions of finite-size rigid particles in a viscous fluid at finite inertia. We explore the system behavior as a function of the particle volume fraction and the Reynolds number (the ratio of flow and particle inertia to viscous forces). Unlike single-phase flows, where a clear distinction exists between the laminar and the turbulent states, three different regimes can be identified in the presence of a particulate phase, with smooth transitions between them. At low volume fractions, the flow becomes turbulent when increasing the Reynolds number, transitioning from the laminar regime dominated by viscous forces to the turbulent regime characterized by enhanced momentum transport by turbulent eddies. At larger volume fractions, we identify a new regime characterized by an even larger increase of the wall friction. The wall friction increases with the Reynolds number (inertial effects) while the turbulent transport is weakly affected, as in a state of intense inertial shear thickening. This state may prevent the transition to a fully turbulent regime at arbitrary high speed of the flow.

Skewness and flatness factors of the longitudinal velocity derivative in wall-bounded flows

NASA Astrophysics Data System (ADS)

Djenidi, Lyazid; Antonia, Robert A.; Talluru, Murali K.; Abe, Hiroyuki

2017-06-01

Hot-wire measurements are carried out in turbulent boundary layers over smooth and rough walls in order the assess the behavior of the skewness (S ) and flatness (F ) factors of the longitudinal velocity derivative as y , the distance from the wall, increases. The measurements are complemented by direct numerical simulations of a smooth wall turbulent channel flow. It is observed that, as the distance to the wall increases, S and F vary significantly before approaching a constant in the outer layer of the boundary layer. Further, S and F exhibit a nontrivial dependence on the Taylor microscale Reynolds number (Reλ). For example, in the region below about 0.2 δ (δ is the boundary layer thickness) where Reλ varies significantly, S and F strongly vary with Reλ and can be multivalued at a given Reλ. In the outer region, between 0.3 δ and 0.6 δ , S , F , and Reλ remain approximately constant. The channel flow direct numerical simulation data for S and F exhibit a similar behavior. These results point to the ambiguity that can arise when assessing the Reλ dependence of S and F in wall shear flows. In particular, the multivaluedness of S and F can lead to erroneous conclusions if y /δ is known only poorly, as is the case for the atmospheric shear layer (ASL). If the laboratory turbulent boundary layer is considered an adequate surrogate to the neutral ASL, then the behavior of S and F in the ASL is expected to be similar to that reported here.

Homoclinic tangle on the edge of shear turbulence.

PubMed

van Veen, Lennaert; Kawahara, Genta

2011-09-09

Experiments and simulations lend mounting evidence for the edge state hypothesis on subcritical transition to turbulence, which asserts that simple states of fluid motion mediate between laminar and turbulent shear flow as their stable manifolds separate the two in state space. In this Letter we describe flows homoclinic to a time-periodic edge state that display the essential properties of turbulent bursting. During a burst, vortical structures and the associated energy dissipation are highly localized near the wall, in contrast with the familiar regeneration cycle.

Pipe flow measurements of turbulence and ambiguity using laser-Doppler velocimetry

NASA Technical Reports Server (NTRS)

Berman, N. S.; Dunning, J. W.

1973-01-01

The laser-Doppler ambiguities predicted by George and Lumley (1973) have been verified experimentally for turbulent pipe flows. Experiments were performed at Reynolds numbers from 5000 to 15,000 at the center line and near the wall. Ambiguity levels were measured from power spectral densities of FM demodulated laser signals and were compared with calculations based on the theory. The turbulent spectra for these water flows after accounting for the ambiguity were equivalent to hot-film measurements at similar Reynolds numbers. The feasibility of laser-Doppler measurements very close to the wall in shear flows is demonstrated.

Flow characteristics and scaling past highly porous wall-mounted fences

NASA Astrophysics Data System (ADS)

Rodríguez-López, Eduardo; Bruce, Paul J. K.; Buxton, Oliver R. H.

2017-07-01

An extensive characterization of the flow past wall-mounted highly porous fences based on single- and multi-scale geometries has been performed using hot-wire anemometry in a low-speed wind tunnel. Whilst drag properties (estimated from the time-averaged momentum equation) seem to be mostly dependent on the grids' blockage ratio; wakes of different size and orientation bars seem to generate distinct behaviours regarding turbulence properties. Far from the near-grid region, the flow is dominated by the presence of two well-differentiated layers: one close to the wall dominated by the near-wall behaviour and another one corresponding to the grid's wake and shear layer, originating from between this and the freestream. It is proposed that the effective thickness of the wall layer can be inferred from the wall-normal profile of root-mean-square streamwise velocity or, alternatively, from the wall-normal profile of streamwise velocity correlation. Using these definitions of wall-layer thickness enables us to collapse different trends of the turbulence behaviour inside this layer. In particular, the root-mean-square level of the wall shear stress fluctuations, longitudinal integral length scale, and spanwise turbulent structure is shown to display a satisfactory scaling with this thickness rather than with the whole thickness of the grid's wake. Moreover, it is shown that certain grids destroy the spanwise arrangement of large turbulence structures in the logarithmic region, which are then re-formed after a particular streamwise extent. It is finally shown that for fences subject to a boundary layer of thickness comparable to their height, the effective thickness of the wall layer scales with the incoming boundary layer thickness. Analogously, it is hypothesized that the growth rate of the internal layer is also partly dependent on the incoming boundary layer thickness.

Analysis of the Casson and Carreau-Yasuda non-Newtonian blood models in steady and oscillatory flows using the lattice Boltzmann method

NASA Astrophysics Data System (ADS)

Boyd, Joshua; Buick, James M.; Green, Simon

2007-09-01

The lattice Boltzmann method is modified to allow the simulation of non-Newtonian shear-dependent viscosity models. Casson and Carreau-Yasuda non-Newtonian blood viscosity models are implemented and are used to compare two-dimensional Newtonian and non-Newtonian flows in the context of simple steady flow and oscillatory flow in straight and curved pipe geometries. It is found that compared to analogous Newtonian flows, both the Casson and Carreau-Yasuda flows exhibit significant differences in the steady flow situation. In the straight pipe oscillatory flows, both models exhibit differences in velocity and shear, with the largest differences occurring at low Reynolds and Womersley numbers. Larger differences occur for the Casson model. In the curved pipe Carreau-Yasuda model, moderate differences are observed in the velocities in the central regions of the geometries, and the largest shear rate differences are observed near the geometry walls. These differences may be important for the study of atherosclerotic progression.

Elastohydrodynamic Lift at a Soft Wall

NASA Astrophysics Data System (ADS)

Davies, Heather S.; Débarre, Delphine; El Amri, Nouha; Verdier, Claude; Richter, Ralf P.; Bureau, Lionel

2018-05-01

We study experimentally the motion of nondeformable microbeads in a linear shear flow close to a wall bearing a thin and soft polymer layer. Combining microfluidics and 3D optical tracking, we demonstrate that the steady-state bead-to-surface distance increases with the flow strength. Moreover, such lift is shown to result from flow-induced deformations of the layer, in quantitative agreement with theoretical predictions from elastohydrodynamics. This study thus provides the first experimental evidence of "soft lubrication" at play at small scale, in a system relevant, for example, to the physics of blood microcirculation.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Loisel, V.; Abbas, M., E-mail: micheline.abbas@ensiacet.fr; Masbernat, O.

Laminar pressure-driven suspension flows are studied in the situation of neutrally buoyant particles at finite Reynolds number. The numerical method is validated for homogeneous particle distribution (no lateral migration across the channel): the increase of particle slip velocities and particle stress with inertia and concentration is in agreement with former works in the literature. In the case of a two-phase channel flow with freely moving particles, migration towards the channel walls due to the Segré-Silberberg effect is observed, leading to the development of a non-uniform concentration profile in the wall-normal direction (the concentration peaks in the wall region and tendsmore » towards zero in the channel core). The particle accumulation in the region of highest shear favors the shear-induced particle interactions and agitation, the profile of which appears to be correlated to the concentration profile. A 1D model predicting particle agitation, based on the kinetic theory of granular flows in the quenched state regime when Stokes number St = O(1) and from numerical simulations when St < 1, fails to reproduce the agitation profile in the wall normal direction. Instead, the existence of secondary flows is clearly evidenced by long time simulations. These are composed of a succession of contra-rotating structures, correlated with the development of concentration waves in the transverse direction. The mechanism proposed to explain the onset of this transverse instability is based on the development of a lift force induced by spanwise gradient of the axial velocity fluctuations. The establishment of the concentration profile in the wall-normal direction therefore results from the combination of the mean flow Segré-Silberberg induced migration, which tends to stratify the suspension and secondary flows which tend to mix the particles over the channel cross section.« less

Electroosmotically Driven Liquid Flows in Complex Micro-Geometries

NASA Astrophysics Data System (ADS)

Dutta, Prashanta; Warburton, Timothy C.; Beskok, Ali

1999-11-01

Electroosmotically driven flows in micro-channels are analyzed analytically and numerically by using a high-order h/p type spectral element simulation suite, Nektar. The high-resolution characteristic of the spectral element method enables us to resolve the sharp electric double layers with successive p-type mesh refinements. For electric double layers that are much smaller than the channel height, the Helmholtz Smoluchowski velocity is used to develop semi-analytical relations for the velocity and the pressure distributions in micro channels. Analytical relations for wall shear stress and pressure distributions are also obtained. These relations show amplification of the normal and shear stresses on the micro-channel walls. Finally, flow through a step-channel is analyzed to document the interaction of the electroosmotic forces with the adverse pressure gradients. Depending on the direction and the magnitude of the electroosmotic force, enhancement or elimination of the separation bubble is observed. These findings can be used to develop innovative strategies for flow control with no moving components and for promotion of mixing in micro-scale geometries.

Scale Effects in the Flow of a Shear-Thinning Fluid in Geological Fractures

NASA Astrophysics Data System (ADS)

Meheust, Y.; Roques, C.; Le Borgne, T.; Selker, J. S.

2017-12-01

Subsurface flow processes involving non-Newtonian fluids play a major role in many engineering applications, from in-situ remediation to enhanced oil recovery. The fluids of interest in such applications (f.e., polymers in remediation) often present shear-thinning properties, i.e., their viscosity decreases as a function of the local shear rate. We investigate how fracture wall roughness impacts the flow of a shear-thinning fluid. Numerical simulations of flow in 3D geological fractures are carried out by solving a modified Navier-Stokes equation incorporating the Carreau viscous-shear model. The numerical fractures consist of two isotropic self-affine surfaces which are correlated with each other above a characteristic scale (thecorrelation length of Méheust et al. PAGEOPH 2003). Perfect plastic closing is assumed when the surfaces are in contact. The statistical parameters describing a fracture are the standard deviation of the wall roughness, the mean aperture, the correlation length, and the fracture length, the Hurst exponent being fixed (equal to 0.8). The objective is to investigate how varying the correlation length impacts the flow behavior, for different degrees of closure, and how this behavior diverges from what is known for Newtonian fluids. The results from the 3D simulations are also compared to 2D simulations based on the lubrication theory, which we have developed as an extension of the Reynolds equation for Newtonian fluids. These 2D simulations run orders of magnitude faster, which allows considering a significant statistics of fractures of identical statistical parameters, and therefore draw general conclusions despite the large stochasticity of the media. We also discuss the implications of our results for solute transport by such flows. References:Méheust, Y., & Schmittbuhl, J. (2003). Scale effects related to flow in rough fractures. Pure and Applied Geophysics, 160(5-6), 1023-1050.

Yield stress materials in soft condensed matter

NASA Astrophysics Data System (ADS)

Bonn, Daniel; Denn, Morton M.; Berthier, Ludovic; Divoux, Thibaut; Manneville, Sébastien

2017-07-01

A comprehensive review is presented of the physical behavior of yield stress materials in soft condensed matter, which encompasses a broad range of materials from colloidal assemblies and gels to emulsions and non-Brownian suspensions. All these disordered materials display a nonlinear flow behavior in response to external mechanical forces due to the existence of a finite force threshold for flow to occur: the yield stress. Both the physical origin and rheological consequences associated with this nonlinear behavior are discussed and an overview is given of experimental techniques available to measure the yield stress. Recent progress is discussed concerning a microscopic theoretical description of the flow dynamics of yield stress materials, emphasizing, in particular, the role played by relaxation time scales, the interplay between shear flow and aging behavior, the existence of inhomogeneous shear flows and shear bands, wall slip, and nonlocal effects in confined geometries.

The hemodynamics in intracranial aneurysm ruptured region with active contrast leakage during computed tomography angiography

NASA Astrophysics Data System (ADS)

Li, Ming-Lung; Wang, Yi-Chou; Liou, Tong-Miin; Lin, Chao-An

2014-10-01

Precise locations of rupture region under contrast agent leakage of five ruptured cerebral artery aneurysms during computed tomography angiography, which is to our knowledge for the first time, were successfully identified among 101 patients. These, together with numerical simulations based on the reconstructed aneurysmal models, were used to analyze hemodynamic parameters of aneurysms under different cardiac cyclic flow rates. For side wall type aneurysms, different inlet flow rates have mild influences on the shear stresses distributions. On the other hand, for branch type aneurysms, the predicted wall shear stress (WSS) correlates strongly with the increase of inlet vessel velocity. The mean and time averaged WSSes at rupture regions are found to be lower than those over the surface of the aneurysms. Also, the levels of the oscillatory shear index (OSI) are higher than the reported threshold value, supporting the assertion that high OSI correlates with rupture of the aneurysm. However, the present results also indicate that OSI level at the rupture region is relatively lower.

Impact of competitive flow on wall shear stress in coronary surgery: computational fluid dynamics of a LIMA-LAD model.

PubMed

Nordgaard, Håvard; Swillens, Abigail; Nordhaug, Dag; Kirkeby-Garstad, Idar; Van Loo, Denis; Vitale, Nicola; Segers, Patrick; Haaverstad, Rune; Lovstakken, Lasse

2010-12-01

Competitive flow from native coronary vessels is considered a major factor in the failure of coronary bypass grafts. However, the pathophysiological effects are not fully understood. Low and oscillatory wall shear stress (WSS) is known to induce endothelial dysfunction and vascular disease, like atherosclerosis and intimal hyperplasia. The aim was to investigate the impact of competitive flow on WSS in mammary artery bypass grafts. Using computational fluid dynamics, WSS was calculated in a left internal mammary artery (LIMA) graft to the left anterior descending artery in a three-dimensional in vivo porcine coronary artery bypass graft model. The following conditions were investigated: high competitive flow (non-significant coronary lesion), partial competitive flow (significant coronary lesion), and no competitive flow (totally occluded coronary vessel). Time-averaged WSS of LIMA at high, partial, and no competitive flow were 0.3-0.6, 0.6-3.0, and 0.9-3.0 Pa, respectively. Further, oscillatory WSS quantified as the oscillatory shear index (OSI) ranged from (maximum OSI = 0.5 equals zero net WSS) 0.15 to 0.35, <0.05, and <0.05, respectively. Thus, high competitive flow resulted in substantial oscillatory and low WSS. Moderate competitive flow resulted in WSS and OSI similar to the no competitive flow condition. Graft flow is highly dependent on the degree of competitive flow. High competitive flow was found to produce unfavourable WSS consistent with endothelial dysfunction and subsequent graft narrowing and failure. Partial competitive flow, however, may be better tolerated as it was found to be similar to the ideal condition of no competitive flow.

Implementation of visual data mining for unsteady blood flow field in an aortic aneurysm.

PubMed

Morizawa, Seiichiro; Shimoyama, Koji; Obayashi, Shigeru; Funamoto, Kenichi; Hayase, Toshiyuki

2011-12-01

This study was performed to determine the relations between the features of wall shear stress and aneurysm rupture. For this purpose, visual data mining was performed in unsteady blood flow simulation data for an aortic aneurysm. The time-series data of wall shear stress given at each grid point were converted to spatial and temporal indices, and the grid points were sorted using a self-organizing map based on the similarity of these indices. Next, the results of cluster analysis were mapped onto the real space of the aortic aneurysm to specify the regions that may lead to aneurysm rupture. With reference to previous reports regarding aneurysm rupture, the visual data mining suggested specific hemodynamic features that cause aneurysm rupture. GRAPHICAL ABSTRACT:

A reduced-dimensional model for near-wall transport in cardiovascular flows

PubMed Central

Hansen, Kirk B.

2015-01-01

Near-wall mass transport plays an important role in many cardiovascular processes, including the initiation of atherosclerosis, endothelial cell vasoregulation, and thrombogenesis. These problems are characterized by large Péclet and Schmidt numbers as well as a wide range of spatial and temporal scales, all of which impose computational difficulties. In this work, we develop an analytical relationship between the flow field and near-wall mass transport for high-Schmidt-number flows. This allows for the development of a wall-shear-stress-driven transport equation that lies on a codimension-one vessel-wall surface, significantly reducing computational cost in solving the transport problem. Separate versions of this equation are developed for the reaction-rate-limited and transport-limited cases, and numerical results in an idealized abdominal aortic aneurysm are compared to those obtained by solving the full transport equations over the entire domain. The reaction-rate-limited model matches the expected results well. The transport-limited model is accurate in the developed flow regions, but overpredicts wall flux at entry regions and reattachment points in the flow. PMID:26298313

An abbreviated Reynolds stress turbulence model for airfoil flows

NASA Technical Reports Server (NTRS)

Gaffney, R. L., Jr.; Hassan, H. A.; Salas, M. D.

1990-01-01

An abbreviated Reynolds stress turbulence model is presented for solving turbulent flow over airfoils. The model consists of two partial differential equations, one for the Reynolds shear stress and the other for the turbulent kinetic energy. The normal stresses and the dissipation rate of turbulent kinetic energy are computed from algebraic relationships having the correct asymptotic near wall behavior. This allows the model to be integrated all the way to the wall without the use of wall functions. Results for a flat plate at zero angle of attack, a NACA 0012 airfoil and a RAE 2822 airfoil are presented.

Modeling Flow Past a Tilted Vena Cava Filter

DOE Office of Scientific and Technical Information (OSTI.GOV)

Singer, M A; Wang, S L

Inferior vena cava filters are medical devices used to prevent pulmonary embolism (PE) from deep vein thrombosis. In particular, retrievable filters are well-suited for patients who are unresponsive to anticoagulation therapy and whose risk of PE decreased with time. The goal of this work is to use computational fluid dynamics to evaluate the flow past an unoccluded and partially occluded Celect inferior vena cava filter. In particular, the hemodynamic response to thrombus volume and filter tilt is examined, and the results are compared with flow conditions that are known to be thrombogenic. A computer model of the filter inside amore » model vena cava is constructed using high resolution digital photographs and methods of computer aided design. The models are parameterized using the Overture software framework, and a collection of overlapping grids is constructed to discretize the flow domain. The incompressible Navier-Stokes equations are solved, and the characteristics of the flow (i.e., velocity contours and wall shear stresses) are computed. The volume of stagnant and recirculating flow increases with thrombus volume. In addition, as the filter increases tilt, the cava wall adjacent to the tilted filter is subjected to low velocity flow that gives rise to regions of low wall shear stress. The results demonstrate the ease of IVC filter modeling with the Overture software framework. Flow conditions caused by the tilted Celect filter may elevate the risk of intrafilter thrombosis and facilitate vascular remodeling. This latter condition also increases the risk of penetration and potential incorporation of the hook of the filter into the vena caval wall, thereby complicating filter retrieval. Consequently, severe tilt at the time of filter deployment may warrant early clinical intervention.« less

Polymer stress tensor in turbulent shear flows.

PubMed

L'vov, Victor S; Pomyalov, Anna; Procaccia, Itamar; Tiberkevich, Vasil

2005-01-01

The interaction of polymers with turbulent shear flows is examined. We focus on the structure of the elastic stress tensor, which is proportional to the polymer conformation tensor. We examine this object in turbulent flows of increasing complexity. First is isotropic turbulence, then anisotropic (but homogenous) shear turbulence, and finally wall bounded turbulence. The main result of this paper is that for all these flows the polymer stress tensor attains a universal structure in the limit of large Deborah number De > 1. We present analytic results for the suppression of the coil-stretch transition at large Deborah numbers. Above the transition the turbulent velocity fluctuations are strongly correlated with the polymer's elongation: there appear high-quality "hydroelastic" waves in which turbulent kinetic energy turns into polymer potential energy and vice versa. These waves determine the trace of the elastic stress tensor but practically do not modify its universal structure. We demonstrate that the influence of the polymers on the balance of energy and momentum can be accurately described by an effective polymer viscosity that is proportional to the cross-stream component of the elastic stress tensor. This component is smaller than the streamwise component by a factor proportional to De2. Finally we tie our results to wall bounded turbulence and clarify some puzzling facts observed in the problem of drag reduction by polymers.

Interaction of aluminum oxide nanoparticles with flow of polyvinyl alcohol solutions base nanofluids over a wedge

NASA Astrophysics Data System (ADS)

Hassan, Mohsan; Faisal, Abrar; Bhatti, Muhammad Mubashir

2018-02-01

Polyvinyl alcohol (PVA) is an important industrial chemical, which is used in numerous chemical engineering applications. It is important to study and predict the flow behavior of PVA solutions and the role of nanoparticles in heat transfer applications to be used in chemical processes on industrial scale. Therefore, the present study deals with the PVA solution-based non-Newtonian Al2O3-nanofluid flow along with heat transfer over wedge. The power-law model is used for this non-Newtonian nanofluid which exhibited shear-thinning behavior. The influences of PVA and nanoparticles concentrations on the characteristics of velocity and temperature profiles are examined graphically. The impacts of these parameters on wall shear stress and convective heat transfer coefficient are also studied through tabular form. During the numerical computations, the impacts of these parameters on flow index and consistency index along with other physical properties of nanofluid are also considered. In this study, we found an improvement in heat transfer and temperature profile of fluid by distribution of Al2O3 nanoparticles. It is also noticed that resistance between adjacent layers of moving fluid is enhanced due to these nanoparticles which leads to decline in velocity profile and increases in shear stress at wall.

Interaction between endothelial cells and albumin encapsulated droplets in Poiseuille flow

NASA Astrophysics Data System (ADS)

Seda, Robinson; Fowlkes, J. Brian; Bull, Joseph

2012-11-01

Acoustic droplet vaporization (ADV) of DDFP encapsulated microdroplets has the ability to transform these emulsions into larger gas emboli capable of occluding blood vessels for therapy. An albumin shell is able to stabilize the droplet's superheated core, but can also interact with endothelial cells (EC) at the vessel wall if in close proximity. Radial migration of these microdroplets could bring them close enough to make this interaction possible leading to bioeffects that include cell detachment and death if an ADV event occurs. The purpose of this study is to investigate the hydrodynamic conditions (i.e. shear stresses) that make possible this EC-droplet interaction. A flow chamber coated with a monolayer of EC and connected to a syringe pump is used to flow a DDFP droplet solution at physiological shear stresses (1-50 dyne/cm2) and inspected for droplet attachment. Droplets have been observed to interact and reversibly attach to EC in a static environment, thus it is expected that at low shear stress values interaction and further attachment will be possible. Knowing the flow conditions at which this interaction is likely to occur will aid in preventative measures to avoid significant bioeffects associated with ADV near the vessel wall. This work is supported by NIH grant R01EB006476.

Numerical studies of laminar and turbulent drag reduction, part 2

NASA Technical Reports Server (NTRS)

Balasubramanian, R.; Orszag, S. A.

1983-01-01

The flow over wave shaped surfaces is studied using a Navier Stokes solver. Detailed comparisons with theoretical results are presented, including the stability of a laminar flow over wavy surfaces. Drag characteristics of nonplanar surfaces are predicted using the Navier-Stokes solver. The secondary instabilities of wall bounded and free shear flows are also discussed.

Application of the Shiono and Knight Method in asymmetric compound channels with different side slopes of the internal wall

NASA Astrophysics Data System (ADS)

Alawadi, Wisam; Al-Rekabi, Wisam S.; Al-Aboodi, Ali H.

2018-03-01

The Shiono and Knight Method (SKM) is widely used to predict the lateral distribution of depth-averaged velocity and boundary shear stress for flows in compound channels. Three calibrating coefficients need to be estimated for applying the SKM, namely eddy viscosity coefficient ( λ), friction factor ( f) and secondary flow coefficient ( k). There are several tested methods which can satisfactorily be used to estimate λ, f. However, the calibration of secondary flow coefficients k to account for secondary flow effects correctly is still problematic. In this paper, the calibration of secondary flow coefficients is established by employing two approaches to estimate correct values of k for simulating asymmetric compound channel with different side slopes of the internal wall. The first approach is based on Abril and Knight (2004) who suggest fixed values for main channel and floodplain regions. In the second approach, the equations developed by Devi and Khatua (2017) that relate the variation of the secondary flow coefficients with the relative depth ( β) and width ratio ( α) are used. The results indicate that the calibration method developed by Devi and Khatua (2017) is a better choice for calibrating the secondary flow coefficients than using the first approach which assumes a fixed value of k for different flow depths. The results also indicate that the boundary condition based on the shear force continuity can successfully be used for simulating rectangular compound channels, while the continuity of depth-averaged velocity and its gradient is accepted boundary condition in simulations of trapezoidal compound channels. However, the SKM performance for predicting the boundary shear stress over the shear layer region may not be improved by only imposing the suitable calibrated values of secondary flow coefficients. This is because difficulties of modelling the complex interaction that develops between the flows in the main channel and on the floodplain in this region.

Comparison of superhydrophobic drag reduction between turbulent pipe and channel flows

NASA Astrophysics Data System (ADS)

Im, Hyung Jae; Lee, Jae Hwa

2017-09-01

It has been known over several decades that canonical wall-bounded internal flows of a pipe and channel share flow similarities, in particular, close to the wall due to the negligible curvature effect. In the present study, direct numerical simulations of fully developed turbulent pipe and channel flows are performed to investigate the influence of the superhydrophobic surfaces (SHSs) on the turbulence dynamics and the resultant drag reduction (DR) of the flows under similar conditions. SHSs at the wall are modeled in spanwise-alternating longitudinal regions with a boundary with no-slip and shear-free conditions, and the two parameters of the spanwise periodicity (P/δ) and SHS fraction (GF) within a pitch are considered. It is shown, in agreement with previous investigations in channels, that the turbulent drag for the pipe and channel flows over SHSs is continuously decreased with increases in P/δ and GF. However, the DR rate in the pipe flows is greater than that in the channel flows with an accompanying reduction of the Reynolds stress. The enhanced performance of the DR for the pipe flow is attributed to the increased streamwise slip and weakened Reynolds shear stress contributions. In addition, a mathematical analysis of the spanwise mean vorticity equation suggests that the presence of a strong secondary flow due to the increased spanwise slip of the pipe flows makes a greater negative contribution of advective vorticity transport than the channel flows, resulting in a higher DR value. Finally, an inspection of the origin of the mean secondary flow in turbulent flows over SHSs based on the spatial gradients of the turbulent kinetic energy demonstrates that the secondary flow is both driven and sustained by spatial gradients in the Reynolds stress components, i.e., Prandtl's secondary flow of the second kind.

Can regurgitant flow damage the left atrial endothelium in patients with prosthetic mechanical heart valves?

PubMed

Milo, Simcha; Zarandi, Mehrdad; Gutfinger, Chaim; Gharib, Morteza

2005-05-01

Previous in-vitro studies of mechanical heart valves (MHVs) in the closed position demonstrated the formation of regurgitant flows, with bubbles and jets forming vortices during each systole. The study aim was to determine whether the regurgitant flow observed in patients with MHVs can damage the left atrial endothelium, due to shear stresses exerted on the endothelial layers. This objective has been accomplished by appropriate in-vitro simulation experiments. In these experiments, leakage flow through several commercial MHVs was investigated. The geometry of the set-up closely resembled that of the left atrial anatomy. Water was forced through the slit of a closed MHV and directed toward the hemispherical cup coated with fluorescent paint. The flow field between the valve and the cup was photographed using high-speed videography, from which local velocities were measured, using digital particle imaging velocimetry. Qualitative damage to the surface of the cup was assessed from the amount of fluorescent paint removed from the cup. The experimental results and calculations indicated that flows through the gaps of the closed valves were sufficient to generate strong vortices, with velocities near the atrial wall in the range of 0.5 to 4.0 m/s, depending on the valve. This led to high shear stresses on the left atrial wall, which far exceeded physiologically acceptable levels. The calculated shear stresses exceeded by orders of magnitude the maximum physiologically tolerated stresses. This suggests that shear stresses associated with regurgitant jets in MHVs may damage the endothelial cells, leading to the activation of the inflammatory reaction, enhanced procoagulation, platelet activation and aggregation, and mechanical cell denudation.

Lubricant dynamics under sliding condition in disk drives

NASA Astrophysics Data System (ADS)

Wu, Lin

2006-07-01

In this paper, we develop a two-dimensional flow model for the lubricant flow dynamics under a sliding head in disk drives. Our two-dimensional model includes important physics such as viscous force, external air shearing stress, air bearing pressure, centrifugal force, disjoining pressure, and surface tension. Our analysis shows that the lubricant flow dynamics under the sliding condition is a fully two-dimensional phenomenon and the circumferential lubricant flow is strongly coupled to the radial flow. It is necessary to have a two-dimensional flow model that couples the circumferential and radial flows together and includes all important physics to achieve realistic predictions. Our results show that the external air shearing stress has a dominant effect on the lubricant flow dynamics. Both velocity slippage at wall and Poiseuille flow effects have to be considered in the evaluation of the air shearing stress under the head. The nonuniform air bearing pressure has a non-negligible effect on the lubricant film dynamics mostly through the Poiseuille flow effect on the air shearing stress but not from its direct pushing or sucking effect on the lubricant surface. Prediction of the formation of lubricant depletion tracks under a sliding head using the two-dimensional model agrees reasonably well with the existing experimental measurements.

Generalized lattice Boltzmann equation with forcing term for computation of wall-bounded turbulent flows.

PubMed

Premnath, Kannan N; Pattison, Martin J; Banerjee, Sanjoy

2009-02-01

In this paper, we present a framework based on the generalized lattice Boltzmann equation (GLBE) using multiple relaxation times with forcing term for eddy capturing simulation of wall-bounded turbulent flows. Due to its flexibility in using disparate relaxation times, the GLBE is well suited to maintaining numerical stability on coarser grids and in obtaining improved solution fidelity of near-wall turbulent fluctuations. The subgrid scale (SGS) turbulence effects are represented by the standard Smagorinsky eddy viscosity model, which is modified by using the van Driest wall-damping function to account for reduction of turbulent length scales near walls. In order to be able to simulate a wider class of problems, we introduce forcing terms, which can represent the effects of general nonuniform forms of forces, in the natural moment space of the GLBE. Expressions for the strain rate tensor used in the SGS model are derived in terms of the nonequilibrium moments of the GLBE to include such forcing terms, which comprise a generalization of those presented in a recent work [Yu, Comput. Fluids 35, 957 (2006)]. Variable resolutions are introduced into this extended GLBE framework through a conservative multiblock approach. The approach, whose optimized implementation is also discussed, is assessed for two canonical flow problems bounded by walls, viz., fully developed turbulent channel flow at a shear or friction Reynolds number (Re) of 183.6 based on the channel half-width and three-dimensional (3D) shear-driven flows in a cubical cavity at a Re of 12 000 based on the side length of the cavity. Comparisons of detailed computed near-wall turbulent flow structure, given in terms of various turbulence statistics, with available data, including those from direct numerical simulations (DNS) and experiments showed good agreement. The GLBE approach also exhibited markedly better stability characteristics and avoided spurious near-wall turbulent fluctuations on coarser grids when compared with the single-relaxation-time (SRT)-based approach. Moreover, its implementation showed excellent parallel scalability on a large parallel cluster with over a thousand processors.

Fibrin, γ’-fibrinogen, and trans-clot pressure gradient control hemostatic clot growth during human blood flow over a collagen/tissue factor wound

PubMed Central

Muthard, Ryan W.; Welsh, John D.; Brass, Lawrence F.; Diamond, Scott L.

2015-01-01

SUMMARY Objective Biological and physical factors interact to modulate blood response in a wounded vessel, resulting in a hemostatic clot or an occlusive thrombus. Flow and pressure differential (ΔP) across the wound from the lumen to the extravascular compartment may impact hemostasis and the observed core/shell architecture. We examined physical and biological factors responsible for regulating thrombin mediated clot growth. Approach and Results Using factor XIIa-inhibited human whole blood perfused in a microfluidic device over collagen/tissue factor at controlled wall shear rate and ΔP, we found thrombin to be highly localized in the P-selectin+ core of hemostatic clots. Increasing ΔP from 9 to 29 mm-Hg (wall shear rate = 400 s−1) reduced P-selectin+ core size and total clot size due to enhanced extravasation of thrombin. Blockade of fibrin polymerization with 5 mM GPRP dysregulated hemostasis by enhancing both P-selectin+ core size and clot size at 400 s−1 (20 mm-Hg). For whole blood flow (no GPRP), the thickness of the P-selectin-negative shell was reduced under arterial conditions (2000 s−1, 20 mm-Hg). Consistent with the antithrombin-1 activity of fibrin implicated with GPRP, anti-γ’-fibrinogen antibody enhanced core-localized thrombin, core size, and overall clot size, especially at venous (100 s−1) but not arterial wall shear rates (2000 s−1). Pathological shear (15,000 s−1) and GPRP synergized to exacerbate clot growth. Conclusions Hemostatic clotting was dependent on core-localized thrombin that (1) triggered platelet P-selectin display and (2) was highly regulated by fibrin and the trans-clot ΔP. Also, γ’-fibrinogen had a role in venous but not arterial conditions. PMID:25614284

Hemodynamic simulations in coronary aneurysms of a patient with Kawasaki Disease

NASA Astrophysics Data System (ADS)

Sengupta, Dibyendu; Marsden, Alison; Burns, Jane

2010-11-01

Kawasaki Disease is the leading cause of acquired pediatric heart disease, and can cause large coronary artery aneurysms in untreated cases. A simulation case study has been performed for a 10-year-old male patient with coronary aneurysms. Specialized coronary boundary conditions along with a lumped parameter heart model mimic the interactions between the ventricles and the coronary arteries, achieving physiologic pressure and flow waveforms. Results show persistent low shear stress in the aneurismal regions, and abnormally high shear at the aneurysm neck. Correlation functions have been derived to compare wall shear stress and wall shear stress gradients with recirculation time with the idea of localizing zones of calcification and thrombosis. Results are compared with those of an artificially created normal coronary geometry for the same patient. The long-term goal of this work is to develop links between hemodynamics and thrombotic risk to assist in clinical decision-making.

Evaluation of Aortic Blood Flow and Wall Shear Stress in Aortic Stenosis and Its Association With Left Ventricular Remodeling

PubMed Central

von Knobelsdorff-Brenkenhoff, Florian; Karunaharamoorthy, Achudhan; Trauzeddel, Ralf Felix; Barker, Alex J; Blaszczyk, Edyta; Markl, Michael; Schulz-Menger, Jeanette

2016-01-01

Background Aortic stenosis (AS) leads to variable stress for the left ventricle (LV) and consequently a broad range of LV remodeling. Study aim was to describe blood flow patterns in the ascending aorta of AS patients and determine their association with remodeling. Methods and Results Thirty-seven patients with AS (14 mild, 8 moderate, 15 severe; age 63±13 years) and 37 healthy controls (age 60±10 years) underwent 4D-flow MRI. Helical and vortical flow formations and flow eccentricity were assessed in the ascending aorta. Normalized flow displacement from the vessel center and peak systolic wall shear stress (WSSpeak) in the ascending aorta were quantified. LV remodeling was assessed based on LV mass index (LVMI-I) and the ratio of LV mass to enddiastolic volume (relative wall mass; RWM). Marked helical and vortical flow formation and eccentricity were more prevalent in patients with AS than in healthy subjects, and AS patients exhibited an asymmetric and elevated distribution of WSSpeak. In AS, aortic orifice area was strongly negatively associated with vortical flow formation (p=0.0274), eccentricity (p=0.0070) and flow displacement (p=0.0021). Bicuspid aortic valve was associated with more intense helical (p=0.0098) and vortical flow formation (p=0.0536), higher flow displacement (p=0.11) and higher WSSpeak (p=0.0926). LVM-I and RWM were significantly associated with aortic orifice area (p=0.0611, p=0.0058) and flow displacement (p=0.0058, p=0.0283). Conclusions In this pilot study, AS leads to abnormal blood flow pattern and WSSpeak in the ascending aorta. In addition to aortic orifice area, normalized flow displacement was significantly associated with LV remodeling. PMID:26917824

Distance-from-the-wall scaling of turbulent motions in wall-bounded flows

NASA Astrophysics Data System (ADS)

Baidya, R.; Philip, J.; Hutchins, N.; Monty, J. P.; Marusic, I.

2017-02-01

An assessment of self-similarity in the inertial sublayer is presented by considering the wall-normal velocity, in addition to the streamwise velocity component. The novelty of the current work lies in the inclusion of the second velocity component, made possible by carefully conducted subminiature ×-probe experiments to minimise the errors in measuring the wall-normal velocity. We show that not all turbulent stress quantities approach the self-similar asymptotic state at an equal rate as the Reynolds number is increased, with the Reynolds shear stress approaching faster than the streamwise normal stress. These trends are explained by the contributions from attached eddies. Furthermore, the Reynolds shear stress cospectra, through its scaling with the distance from the wall, are used to assess the wall-normal limits where self-similarity applies within the wall-bounded flow. The results are found to be consistent with the recent prediction from the work of Wei et al. ["Properties of the mean momentum balance in turbulent boundary layer, pipe and channel flows," J. Fluid Mech. 522, 303-327 (2005)], Klewicki ["Reynolds number dependence, scaling, and dynamics of turbulent boundary layers," J. Fluids Eng. 132, 094001 (2010)], and others that the self-similar region starts and ends at z+˜O (√{δ+}) and O (δ+) , respectively. Below the self-similar region, empirical evidence suggests that eddies responsible for turbulent stresses begin to exhibit distance-from-the-wall scaling at a fixed z+ location; however, they are distorted by viscous forces, which remain a leading order contribution in the mean momentum balance in the region z+≲O (√{δ+}) , and thus result in a departure from self-similarity.

Skin-Friction Measurements in Incompressible Flow

NASA Technical Reports Server (NTRS)

Smith, Donald W.; Walker, John H.

1959-01-01

Experiments have been conducted to measure the local surface-shear stress and the average skin-friction coefficient in Incompressible flow for a turbulent boundary layer on a smooth flat plate having zero pressure gradient. Data were obtained for a range of Reynolds numbers from 1 million to 45 million. The local surface-shear stress was measured by a floating-element skin-friction balance and also by a calibrated total head tube located on the surface of the test wall. The average skin-friction coefficient was obtained from boundary-layer velocity profiles.

Drag reduction at a plane wall

NASA Technical Reports Server (NTRS)

Hill, D. C.

1993-01-01

The objective is to determine by analytical means how drag on a plane wall may be modified favorably using a minimal amount of flow information - preferably only information at the wall. What quantities should be measured? How should that information be assimilated in order to arrive at effective control? As a prototypical problem, incompressible, viscous flow, governed by the Navier-Stokes equations, past a plane wall at which the no-slip condition was modified was considered. The streamwise and spanwise velocity components are required to be zero, but the normal component is to be specified according to some control law. The challenge is to choose the wall-normal velocity component based on flow conditions at the wall so that the mean drag is as small as possible. There can be no net mass flux through the wall, and the total available control energy is constrained. A turbulent flow is highly unsteady and has detailed spatial structure. The mean drag on the wall is the integral over the wall of the local shear forces exerted by the fluid, which is then averaged in time; it is a 'macroscopic' property of the flow. It is not obvious how unsteady boundary control is to be applied in order to modify the mean flow most effectively, especially in view of the non- self-adjoint nature of the governing equations. An approximate analytical solution to the suboptimal scheme is pursued.

Assessment of turbulent flow effects on the vessel wall using four-dimensional flow MRI.

PubMed

Ziegler, Magnus; Lantz, Jonas; Ebbers, Tino; Dyverfeldt, Petter

2017-06-01

To explore the use of MR-estimated turbulence quantities for the assessment of turbulent flow effects on the vessel wall. Numerical velocity data for two patient-derived models was obtained using computational fluid dynamics (CFD) for two physiological flow rates. The four-dimensional (4D) Flow MRI measurements were simulated at three different spatial resolutions and used to investigate the estimation of turbulent wall shear stress (tWSS) using the intravoxel standard deviation (IVSD) of velocity and turbulent kinetic energy (TKE) estimated near the vessel wall. Accurate estimation of tWSS using the IVSD is limited by the spatial resolution achievable with 4D Flow MRI. TKE, estimated near the wall, has a strong linear relationship to the tWSS (mean R 2  = 0.84). Near-wall TKE estimates from MR simulations have good agreement to CFD-derived ground truth (mean R 2  = 0.90). Maps of near-wall TKE have strong visual correspondence to tWSS. Near-wall estimation of TKE permits assessment of relative maps of tWSS, but direct estimation of tWSS is challenging due to limitations in spatial resolution. Assessment of tWSS and near-wall TKE may open new avenues for analysis of different pathologies. Magn Reson Med 77:2310-2319, 2017. © 2016 International Society for Magnetic Resonance in Medicine. © 2016 International Society for Magnetic Resonance in Medicine.

Simulation of non-Newtonian oil-water core annular flow through return bends

NASA Astrophysics Data System (ADS)

Jiang, Fan; Wang, Ke; Skote, Martin; Wong, Teck Neng; Duan, Fei

2018-01-01

The volume of fluid (VOF) model is used together with the continuum surface force (CSF) model to numerically simulate the non-Newtonian oil-water core annular flow across return bends. A comprehensive study is conducted to generate the profiles of pressure, velocity, volume fraction and wall shear stress for different oil properties, flow directions, and bend geometries. It is revealed that the oil core may adhere to the bend wall under certain operating conditions. Through the analysis of the total pressure gradient and fouling angle, suitable bend geometric parameters are identified for avoiding the risk of fouling.

Patient specific 3-d modeling of blood flow in a multi-stenosed left coronary artery.

PubMed

Kamangar, Sarfaraz; Badruddin, Irfan Anjum; Ameer Ahamad, N; Soudagar, Manzoor Elahi M; Govindaraju, Kalimuthu; Nik-Ghazali, N; Salman Ahmed, N J; Yunus Khan, T M

2017-01-01

The current study investigates the effect of multi stenosis on the hemodynamic parameters such as wall pressure, velocity and wall shear stress in the realistic left coronary artery. Patients CT scan image data of normal and diseased left coronary artery was chosen for the reconstruction of 3D coronary artery models. The diseased 3D model of left coronary artery shows a narrowing of more than 70% and 80% of area stenosis (AS) at the left main stem (LMS) and left circumflex (LCX) respectively. The results show that the decrease in pressure was found downstream to the stenosis as compared to the coronary artery without stenosis. The maximum pressure drop was noted across the 80% AS at the left circumflex branch. The recirculation zone was also observed immediate to the stenosis and highest wall shear stress was found across the 80% area stenosis. Our analysis provides an insight into the distribution of wall shear stress and pressure drop, thus improving our understanding on the hemodynamics in realistic coronary artery.

Regime of aggregate structures and magneto-rheological characteristics of a magnetic rod-like particle suspension: Monte Carlo and Brownian dynamics simulations

NASA Astrophysics Data System (ADS)

Okada, Kazuya; Satoh, Akira

2017-09-01

In the present study, we address a suspension composed ferromagnetic rod-like particles to elucidate a regime change in the aggregate structures and the magneto-rheological characteristics. Monte Carlo simulations have been employed for investigating the aggregate structures in thermodynamic equilibrium, and Brownian dynamics simulations for magneto-rheological features in a simple shear flow. The main results obtained here are summarized as follows. For the case of thermodynamic equilibrium, the rod-like particles aggregate to form thick chain-like clusters and the neighboring clusters incline in opposite directions. If the external magnetic field is increased, the thick chain-like clusters in the magnetic field direction grow thicker by adsorbing the neighboring clusters that incline in the opposite direction. Hence, a significant phase change in the particle aggregates is not induced by an increase in the magnetic field strength. For the case of a simple shear flow, even a weak shear flow induces a significant regime change from the thick chain-like clusters of thermodynamic equilibrium into wall-like aggregates composed of short raft-like clusters. A strong external magnetic field drastically changes these aggregates into wall-like aggregates composed of thick chain-like clusters rather than the short raft-like clusters. The internal structure of these aggregates is not strongly influenced by a shear flow, and the formation of the short raft-like clusters is maintained inside the aggregates. The main contribution to the net viscosity is the viscosity component due to magnetic particle-particle interaction forces in relation to the present volumetric fraction. Hence, a larger magnetic interaction strength and also a stronger external magnetic field give rise to a larger magneto-rheological effect. However, the dependence of the viscosity on these factors is governed in a complex manner by whether or not the wall-like aggregates are composed mainly of short raft-like clusters. An increase in the shear rate functions to simply decrease the effect of the magnetic particle-particle and the particle-field interactions.

Analysis of the leading edge effects on the boundary layer transition

NASA Technical Reports Server (NTRS)

Chow, Pao-Liu

1990-01-01

A general theory of boundary layer control by surface heating is presented. Some analytical results for a simplified model, i.e., the optimal control of temperature fluctuations in a shear flow are described. The results may provide a clue to the effectiveness of the active feedback control of a boundary layer flow by wall heating. In a practical situation, the feedback control may not be feasible from the instrumentational point of view. In this case the vibrational control introduced in systems science can provide a useful alternative. This principle is briefly explained and applied to the control of an unstable wavepacket in a parallel shear flow.

Nonlinear dynamics and rheology of active fluids: simulations in two dimensions.

PubMed

Fielding, S M; Marenduzzo, D; Cates, M E

2011-04-01

We report simulations of a continuum model for (apolar, flow aligning) active fluids in two dimensions. Both free and anchored boundary conditions are considered, at parallel confining walls that are either static or moving at fixed relative velocity. We focus on extensile materials and find that steady shear bands, previously shown to arise ubiquitously in one dimension for the active nematic phase at small (or indeed zero) shear rate, are generally replaced in two dimensions by more complex flow patterns that can be stationary, oscillatory, or apparently chaotic. The consequences of these flow patterns for time-averaged steady-state rheology are examined. ©2011 American Physical Society

Numerical investigations of the unsteady blood flow in the end-to-side arteriovenous fistula for hemodialysis.

PubMed

Jodko, Daniel; Obidowski, Damian; Reorowicz, Piotr; Jóźwik, Krzysztof

2016-01-01

The aim of this study was to investigate the blood flow in the end-to-side arteriovenous (a-v) fistula, taking into account its pulsating nature and the patient-specific geometry of blood vessels. Computational Fluid Dynamics (CFD) methods were used for this analysis. DICOM images of the fistula, obtained from the angio-computed tomography, were a source of the data applied to develop a 3D geometrical model of the fistula. The model was meshed, then the ANSYS CFX v. 15.0 code was used to perform simulations of the flow in the vessels under analysis. Mesh independence tests were conducted. The non-Newtonian rheological model of blood and the Shear Stress Transport model of turbulence were employed. Blood vessel walls were assumed to be rigid. Flow patterns, velocity fields, the volume flow rate, the wall shear stress (WSS) propagation on particular blood vessel walls were shown versus time. The maximal value of the blood velocity was identified in the anastomosis - the place where the artery is connected to the vein. The flow rate was calculated for all veins receiving blood. The blood flow in the geometrically complicated a-v fistula was simulated. The values and oscillations of the WSS are the largest in the anastomosis, much lower in the artery and the lowest in the cephalic vein. A strong influence of the mesh on the results concerning the maximal and area-averaged WSS was shown. The relation between simulations of the pulsating and stationary flow under time-averaged flow conditions was presented.

Melt fracture revisited

DOE Office of Scientific and Technical Information (OSTI.GOV)

Greenberg, J. M.

2003-07-16

In a previous paper the author and Demay advanced a model to explain the melt fracture instability observed when molten linear polymer melts are extruded in a capillary rheometer operating under the controlled condition that the inlet flow rate was held constant. The model postulated that the melts were a slightly compressible viscous fluid and allowed for slipping of the melt at the wall. The novel feature of that model was the use of an empirical switch law which governed the amount of wall slip. The model successfully accounted for the oscillatory behavior of the exit flow rate, typically referredmore » to as the melt fracture instability, but did not simultaneously yield the fine scale spatial oscillations in the melt typically referred to as shark skin. In this note a new model is advanced which simultaneously explains the melt fracture instability and shark skin phenomena. The model postulates that the polymer is a slightly compressible linearly viscous fluid but assumes no slip boundary conditions at the capillary wall. In simple shear the shear stress {tau}and strain rate d are assumed to be related by d = F{tau} where F ranges between F{sub 2} and F{sub 1} > F{sub 2}. A strain rate dependent yield function is introduced and this function governs whether F evolves towards F{sub 2} or F{sub 1}. This model accounts for the empirical observation that at high shears polymers align and slide more easily than at low shears and explains both the melt fracture and shark skin phenomena.« less

Effects of Soluble Surfactant on Lateral Migration of a Bubble in a Shear Flow

NASA Astrophysics Data System (ADS)

Muradoglu, Metin; Tryggvason, Gretar

2014-11-01

Motivated by the recent experimental study of Takagi et al. (2008), direct numerical simulations are performed to examine effects of soluble surfactant on the lateral migration of a deformable bubble in a pressure-driven channel flow. The interfacial and bulk surfactant concentration evolution equations are solved fully coupled with the incompressible Navier-Stokes equations. A non-linear equation of state is used to relate interfacial surface tension to surfactant concentration at the interface. A multiscale method is developed to handle the mass exchange between the interface and bulk fluid at high Peclet numbers, using a boundary-layer approximation next to the bubble and a relatively coarse grid for the rest of the flow. It is found that the surfactant induced Marangoni stresses can dominate over the shear-induced lift force and thus alter the behavior of the bubble completely, i.e., the contaminated bubble drifts away from the channel wall and stabilizes at the center of the channel in contrast with the corresponding clean bubble that drifts toward the wall and stabilizes near the wall. The Scientific and Technical Research Council of Turkey (TUBITAK), Grant 112M181 and Turkish Academy of Sciences (TUBA).

Integral Method for the Assessment of U-RANS Effectiveness in Non-Equilibrium Flows and Heat Transfer

NASA Astrophysics Data System (ADS)

Pond, Ian; Edabi, Alireza; Dubief, Yves; White, Christopher

2015-11-01

Reynolds Average Navier Stokes (RANS) modeling has established itself as a critical design tool in many engineering applications, thanks to its superior computational efficiency. The drawbacks of RANS models are well known, but not necessarily well understood: poor prediction of transition, non equilibrium flows, mixing and heat transfer, to name the ones relevant to our study. In the present study, we use a DNS of a reciprocating channel flow driven by an oscillating pressure gradient to test several low- and high-Reynolds RANS models. Temperature is introduced as a passive scalar to study heat transfer modeling. Low-Reynolds models manage to capture the overall physics of wall shear and heat flux well, yet with some phase discrepancies, whereas high Reynolds models fail. Under the microscope of the integral method for wall shear and wall heat flux, the qualitative agreement appears more serendipitous than driven by the ability of the models to capture the correct physics. The integral method is shown to be more insightful in the benchmarking of RANS models than the typical comparisons of statistical quantities. The authors acknowledges the support of NSF and DOE under grant NSF/DOE 1258697 (VT) and 1258702 (NH).

Design Optimization of Vena Cava Filters: An application to dual filtration devices

DOE Office of Scientific and Technical Information (OSTI.GOV)

Singer, M A; Wang, S L; Diachin, D P

Pulmonary embolism (PE) is a significant medical problem that results in over 300,000 fatalities per year. A common preventative treatment for PE is the insertion of a metallic filter into the inferior vena cava that traps thrombi before they reach the lungs. The goal of this work is to use methods of mathematical modeling and design optimization to determine the configuration of trapped thrombi that minimizes the hemodynamic disruption. The resulting configuration has implications for constructing an optimally designed vena cava filter. Computational fluid dynamics is coupled with a nonlinear optimization algorithm to determine the optimal configuration of trapped modelmore » thrombus in the inferior vena cava. The location and shape of the thrombus are parameterized, and an objective function, based on wall shear stresses, determines the worthiness of a given configuration. The methods are fully automated and demonstrate the capabilities of a design optimization framework that is broadly applicable. Changes to thrombus location and shape alter the velocity contours and wall shear stress profiles significantly. For vena cava filters that trap two thrombi simultaneously, the undesirable flow dynamics past one thrombus can be mitigated by leveraging the flow past the other thrombus. Streamlining the shape of thrombus trapped along the cava wall reduces the disruption to the flow, but increases the area exposed to abnormal wall shear stress. Computer-based design optimization is a useful tool for developing vena cava filters. Characterizing and parameterizing the design requirements and constraints is essential for constructing devices that address clinical complications. In addition, formulating a well-defined objective function that quantifies clinical risks and benefits is needed for designing devices that are clinically viable.« less

Wall-resolved spectral cascade-transport turbulence model

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brown, C. S.; Shaver, D. R.; Lahey, R. T.

A spectral cascade-transport model has been developed and applied to turbulent channel flows (Reτ= 550, 950, and 2000 based on friction velocity, uτ ; or ReδΜ= 8,500; 14,800 and 31,000, based on the mean velocity and channel half-width). This model is an extension of a spectral model previously developed for homogeneous single and two-phase decay of isotropic turbulence and uniform shear flows; and a spectral turbulence model for wall-bounded flows without resolving the boundary layer. Data from direct numerical simulation (DNS) of turbulent channel flow was used to help develop this model and to assess its performance in the 1Dmore » direction across the channel width. The resultant spectral model is capable of predicting the mean velocity, turbulent kinetic energy and energy spectrum distributions for single-phase wall-bounded flows all the way to the wall, where the model source terms have been developed to account for the wall influence. We implemented the model into the 3D multiphase CFD code NPHASE-CMFD and the latest results are within reasonable error of the 1D predictions.« less

Wall-resolved spectral cascade-transport turbulence model

DOE PAGES

Brown, C. S.; Shaver, D. R.; Lahey, R. T.; ...

2017-07-08

A spectral cascade-transport model has been developed and applied to turbulent channel flows (Reτ= 550, 950, and 2000 based on friction velocity, uτ ; or ReδΜ= 8,500; 14,800 and 31,000, based on the mean velocity and channel half-width). This model is an extension of a spectral model previously developed for homogeneous single and two-phase decay of isotropic turbulence and uniform shear flows; and a spectral turbulence model for wall-bounded flows without resolving the boundary layer. Data from direct numerical simulation (DNS) of turbulent channel flow was used to help develop this model and to assess its performance in the 1Dmore » direction across the channel width. The resultant spectral model is capable of predicting the mean velocity, turbulent kinetic energy and energy spectrum distributions for single-phase wall-bounded flows all the way to the wall, where the model source terms have been developed to account for the wall influence. We implemented the model into the 3D multiphase CFD code NPHASE-CMFD and the latest results are within reasonable error of the 1D predictions.« less

Turbulent Boundary Layer Drag Reduction by Spanwise Wall Oscillation

NASA Astrophysics Data System (ADS)

Trujillo, S. M.; Bogard, D. G.; Ball, K. S.

1997-11-01

Changes in turbulence structure were investigated in a turbulent water boundary layer flow for which wall shear had been reduced 25 percent by spanwise wall oscillations. LDV and hot film measurements were made of streamwise and wall-normal velocities. For all wall oscillations examined, drag reduction was found to scale best with the peak velocity of the wall oscillation. Burst and sweep strength and duration were all reduced by the wall oscillation, with the greatest effects seen for the strongest events. The pdf of the velocity in the near-wall region showed greatly increased periods of low velocities, but little change was observed in the streamwise velocity autocorrelation.

A modification of Murray's law for shear-thinning rheology.

PubMed

McGah, Patrick M; Capobianchi, Massimo

2015-05-01

This study reformulates Murray's well-known principle of minimum work as applied to the cardiovascular system to include the effects of the shear-thinning rheology of blood. The viscous behavior is described using the extended modified power law (EMPL), which is a time-independent, but shear-thinning rheological constitutive equation. The resulting minimization problem is solved numerically for typical parameter ranges. The non-Newtonian analysis still predicts the classical cubic diameter dependence of the volume flow rate and the cubic branching law. The current analysis also predicts a constant wall shear stress throughout the vascular tree, albeit with a numerical value about 15-25% higher than the Newtonian analysis. Thus, experimentally observed deviations from the cubic branching law or the predicted constant wall shear stress in the vasculature cannot likely be attributed to blood's shear-thinning behavior. Further differences between the predictions of the non-Newtonian and the Newtonian analyses are highlighted, and the limitations of the Newtonian analysis are discussed. Finally, the range and limits of applicability of the current results as applied to the human arterial tree are also discussed.

The effect of wall geometry in particle-laden turbulent flow

NASA Astrophysics Data System (ADS)

Abdehkakha, Hoora; Iaccarino, Gianluca

2016-11-01

Particle-laden turbulent flow plays a significant role in various industrial applications, as turbulence alters the exchange of momentum and energy between particles and fluid flow. In wall-bounded flows, inhomogeneity in turbulent properties is the primary cause of turbophoresis that leads the particles toward the walls. Conversely, shear-induced lift force on the particles can become important if large scale vortical structures are present. The objective of this study is to understand the effects of geometry on fluid flows and consequently on particles transport and concentration. Direct numerical simulations combined with point particle Lagrangian tracking are performed for several geometries such as a pipe, channel, square duct, and squircle (rounded-corners duct). In non-circular ducts, anisotropic and inhomogeneous Reynolds stresses are the most influential phenomena that produce the secondary flows. It has been shown that these motions can have a significant impact on transporting momentum, vorticity, and energy from the core of the duct to the corners. The main focus of the present study is to explore the effects of near the wall structures and secondary flows on turbophoresis, lift, and particle concentration.

Scaled-Up Fabrication of Thin-Walled ZK60 Tubing using Shear Assisted Processing and Extrusion (ShAPE)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Whalen, Scott A.; Joshi, Vineet V.; Overman, Nicole R.

Shear Assisted Processing and Extrusion (ShAPE) has been scaled-up and applied to direct extrusion of thin-walled magnesium tubing. Using ShAPE, billets of ZK60A-T5 were directly extruded into round tubes having an outer diameter of 50.8 mm and wall thickness of 1.52 mm. The severe shearing conditions inherent to ShAPE resulted in microstructural refinement with an average grain size of 3.8μm measured at the midpoint of the tube wall. Tensile testing per ATSM E-8 on specimens oriented parallel to the extrusion direction gave an ultimate tensile strength of 254.4 MPa and elongation of 20.1%. Specimens tested perpendicular to the extrusion directionmore » had an ultimate tensile strength of 297.2 MPa and elongation of 25.0%. Due to material flow effects resulting from the simultaneous linear and rotational shear intrinsic to ShAPE, ram force and electrical power consumption during extrusion were just 40 kN and 11.5 kW respectively. This represents a significant reduction in ram force and power consumption compared to conventional extrusion. As such, there is potential for ShAPE to offer a scalable, lower cost extrusion option with potentially improved bulk mechanical properties.« less

Boundary Effects and Shear Thickening of Colloidal Suspensions: A study based on measurement of Suspension Microstructure

NASA Astrophysics Data System (ADS)

Perera, M. Tharanga D.

Microstructure is key to understanding rheological behaviors of flowing particulate suspensions. During the past decade, Stokesian Dynamics simulations have been the dominant method of determining suspension microstructure. Structure results obtained numerically reveal that an anisotropic structure is formed under high Peclet (Pe) number conditions. Researchers have used various experimental techniques such as small angle neutron scattering (SANS) and light scattering methods to validate microstructure. This work outlines an experimental technique based on confocal microscopy to study microstructure of a colloidal suspension in an index-matched fluid flowing in a microchannel. High resolution scans determining individual particle locations in suspensions 30-50 vol % yield quantitative results of the local microstructure in the form of the pair distribution function, g(r). From these experimentally determined g(r), the effect of shear rate, quantified by the Peclet number as a ratio of shear and Brownian stress, on the suspension viscosity and normal stress follow that seen in macroscopic rheological measurements and simulations. It is generally believed that shear thickening behavior of colloidal suspensions is driven by the formation of hydroclusters. From measurements of particle locations, hydroclusters are identified. The number of hydroclusters grows exponentially with increasing Pe, and the onset of shear thickening is driven by the increase in formation of clusters having 5-8 particles. At higher Pe, we notice the emergence of 12 or more particle clusters. The internal structure of these hydroclusters has been investigated, and there is some evidence that particles internal to hydroclusters preferentially align along the 45° and 135° axis. Beyond observations of bulk suspension behavior, the influence of boundaries on suspension microstructure is also investigated. Experiments were performed for suspensions flowing over smooth walls, made of glass coverslips, and over rough walls having a high density coating of particles. These results show that there is more order in structure near smooth boundaries while near rough boundaries the structure is similar to that found in the bulk. The relative viscosity and normal stress differences also indicate that boundaries have an effect up as far as 6 particle diameters away from the boundary. Finally, we investigate the microstructure evolvement in a model porous medium and notice that such boundary effects come into play in such real process flows. The confocal microscopy technique also provides us with the advantage of measuring structure in real process flows. We have investigated how the microstructure evolves upstream and downstream in a porous medium. We notice more structure in a high volume fraction suspension and notice anisotropic behavior at regions where shear from the wall of the posts dominate. In other cases, a mixed flow behavior is observed due to collisions between pore surfaces and other particles resulting in a deviation from flow streamlines.

Additive erosion reduction influences in the turbulent boundary layer

NASA Astrophysics Data System (ADS)

Buckingham, A. C.

1981-05-01

Results of a sequence of flow, heat and mass transfer calculations are presented which theoretically characterize the erosive environment at the wall surface of refractory metal coated and uncoated gun barrels. The theoretical results include analysis of the wall surface temperature, heat flux, and shear stress time histories on thin (10 mil.) Cr, Mo, Nb, and Ta plated steel barrel walls as uncoated steel walls. The calculations combine effects of a number of separate processes which were previously (and purposely) studied individually. These include solid particle additive concentrations, gas wall thermochemical influences, and transient turbulent wall boundary layer flow with multicomponent molecular diffusion and reactions from interaction of propellant combustion and the eroding surface. The boundary layer model includes particulate additive concentrations as well as propellant combustion products, considered for the present to be in the local thermochemical equilibrium.

Drop deformation and breakup in a partially filled horizontal rotating cylinder

NASA Astrophysics Data System (ADS)

White, Andrew; Pereira, Caroline; Hyacinthe, Hyaquino; Ward, Thomas

2014-11-01

Drop deformation and breakup due to shear flow has been studied extensively in Couette devices as well as in gravity-driven flows. In these cases shear is generated either by the moving wall or the drop's motion. For such flows the drop shape remains unperturbed at low capillary number (Ca), deforms at moderate Ca , and can experience breakup as Ca --> 1 and larger. Here single drops of NaOH(aq) will be placed in a horizontal cylindrical rotating tank partially filled with vegetable oil resulting in 10-2 < Ca <101 . It will be shown that the reactive vegetable oil-NaOH(aq) system, where surfactants are produced in situ by saponification, can yield lower minimum surface tensions and faster adsorption than non-reactive surfactant systems. Oil films between the wall and drop as well as drop shape will be observed as rotation rates and NaOH(aq) concentration are varied. Results will be presented in the context of previous work on bubble and drop shapes and breakup. NSF CBET #1262718.

Experimental observations of a complex, supersonic nozzle concept

NASA Astrophysics Data System (ADS)

Magstadt, Andrew; Berry, Matthew; Glauser, Mark; Ruscher, Christopher; Gogineni, Sivaram; Kiel, Barry; Skytop Turbulence Labs, Syracuse University Team; Spectral Energies, LLC. Team; Air Force Research Laboratory Team

2015-11-01

A complex nozzle concept, which fuses multiple canonical flows together, has been experimentally investigated via pressure, schlieren and PIV in the anechoic chamber at Syracuse University. Motivated by future engine designs of high-performance aircraft, the rectangular, supersonic jet under investigation has a single plane of symmetry, an additional shear layer (referred to as a wall jet) and an aft deck representative of airframe integration. Operating near a Reynolds number of 3 ×106 , the nozzle architecture creates an intricate flow field comprised of high turbulence levels, shocks, shear & boundary layers, and powerful corner vortices. Current data suggest that the wall jet, which is an order of magnitude less energetic than the core, has significant control authority over the acoustic power through some non-linear process. As sound is a direct product of turbulence, experimental and analytical efforts further explore this interesting phenomenon associated with the turbulent flow. The authors acknowledge the funding source, a SBIR Phase II project with Spectral Energies, LLC. and AFRL turbine engine branch under the direction of Dr. Barry Kiel.

Aerodynamic heating effects on wall-modeled large-eddy simulations of high-speed flows

NASA Astrophysics Data System (ADS)

Yang, Xiang; Urzay, Javier; Moin, Parviz

2017-11-01

Aerospace vehicles flying at high speeds are subject to increased wall-heating rates because of strong aerodynamic heating in the near-wall region. In wall-modeled large-eddy simulations (WMLES), this near-wall region is typically not resolved by the computational grid. As a result, the effects of aerodynamic heating need to be modeled using an LES wall model. In this investigation, WMLES of transitional and fully turbulent high-speed flows are conducted to address this issue. In particular, an equilibrium wall model is employed in high-speed turbulent Couette flows subject to different combinations of thermal boundary conditions and grid sizes, and in transitional hypersonic boundary layers interacting with incident shock waves. Specifically, the WMLES of the Couette-flow configuration demonstrate that the shear-stress and heat-flux predictions made by the wall model show only a small sensitivity to the grid resolution even in the most adverse case where aerodynamic heating prevails near the wall and generates a sharp temperature peak there. In the WMLES of shock-induced transition in boundary layers, the wall model is tested against DNS and experiments, and it is shown to capture the post-transition aerodynamic heating and the overall heat transfer rate around the shock-impingement zone. This work is supported by AFOSR.

Recommendations for Achieving Accurate Numerical Simulation of Tip Clearance Flows in Transonic Compressor Rotors

NASA Technical Reports Server (NTRS)

VanZante, Dale E.; Strazisar, Anthony J.; Wood, Jerry R,; Hathaway, Michael D.; Okiishi, Theodore H.

2000-01-01

The tip clearance flows of transonic compressor rotors are important because they have a significant impact on rotor and stage performance. While numerical simulations of these flows are quite sophisticated. they are seldom verified through rigorous comparisons of numerical and measured data because these kinds of measurements are rare in the detail necessary to be useful in high-speed machines. In this paper we compare measured tip clearance flow details (e.g. trajectory and radial extent) with corresponding data obtained from a numerical simulation. Recommendations for achieving accurate numerical simulation of tip clearance flows are presented based on this comparison. Laser Doppler Velocimeter (LDV) measurements acquired in a transonic compressor rotor, NASA Rotor 35, are used. The tip clearance flow field of this transonic rotor was simulated using a Navier-Stokes turbomachinery solver that incorporates an advanced k-epsilon turbulence model derived for flows that are not in local equilibrium. Comparison between measured and simulated results indicates that simulation accuracy is primarily dependent upon the ability of the numerical code to resolve important details of a wall-bounded shear layer formed by the relative motion between the over-tip leakage flow and the shroud wall. A simple method is presented for determining the strength of this shear layer.

Coherent instability in wall-bounded turbulence

NASA Astrophysics Data System (ADS)

Hack, M. J. Philipp

2017-11-01

Hairpin vortices are commonly considered one of the major classes of coherent fluid motions in shear layers, even as their significance in the grand scheme of turbulence has remained an openly debated question. The statistical prevalence of the dynamic process that gives rise to the hairpins across different types of flows suggests an origin in a robust common mechanism triggered by conditions widespread in wall-bounded shear layers. This study seeks to shed light on the physical process which drives the generation of hairpin vortices. It is primarily facilitated through an algorithm based on concepts developed in the field of computer vision which allows the topological identification and analysis of coherent flow processes across multiple scales. Application to direct numerical simulations of boundary layers enables the time-resolved sampling and exploration of the hairpin process in natural flow. The analysis yields rich statistical results which lead to a refined characterization of the hairpin process. Linear stability theory offers further insight into the flow physics and especially into the connection between the hairpin and exponential amplification mechanisms. The results also provide a sharpened understanding of the underlying causality of events.

FFR analysis of blood flow through a stenosed Left Anterior Descending Artery

NASA Astrophysics Data System (ADS)

Pasupathi, Jawahar; Arul Prakash, K.

2017-11-01

The numerical analyisis of blood flow through a stenosed tapering Left Anterior Descending (LAD) artery was done using Streamwise Upwind Petrov Galerkin (SUPG) method to obtain the clinical parameters such as Fractional Flow reserve (FFR) and Wall Shear Stress (WSS). The geometry was considered to be a straight tapering cylindrical duct with the severity of stenosis modeled using a curve equation based on the reduction in diameter at the stenosed region. Poiseuille velocity profile was given at the inlet such that at each time step the product of mean velocity and the inlet area gives the realistic flow rate through the LAD. The simulation was done for 30,50 and 70 percent reduction in cross-section of LAD. The average pressure values across the stenosis was used to quantify FFR. The FFR increased with higher pressure ratio across the stenosis, which is a result of increased severity of stenosis. The velocity gradients that are responsible for the shear stress at the walls were found to be dependent on the shape of the stenosis, i.e., the diameter and its length.

Computational Fluid Dynamic simulations of pipe elbow flow.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Homicz, Gregory Francis

2004-08-01

One problem facing today's nuclear power industry is flow-accelerated corrosion and erosion in pipe elbows. The Korean Atomic Energy Research Institute (KAERI) is performing experiments in their Flow-Accelerated Corrosion (FAC) test loop to better characterize these phenomena, and develop advanced sensor technologies for the condition monitoring of critical elbows on a continuous basis. In parallel with these experiments, Sandia National Laboratories is performing Computational Fluid Dynamic (CFD) simulations of the flow in one elbow of the FAC test loop. The simulations are being performed using the FLUENT commercial software developed and marketed by Fluent, Inc. The model geometry and meshmore » were created using the GAMBIT software, also from Fluent, Inc. This report documents the results of the simulations that have been made to date; baseline results employing the RNG k-e turbulence model are presented. The predicted value for the diametrical pressure coefficient is in reasonably good agreement with published correlations. Plots of the velocities, pressure field, wall shear stress, and turbulent kinetic energy adjacent to the wall are shown within the elbow section. Somewhat to our surprise, these indicate that the maximum values of both wall shear stress and turbulent kinetic energy occur near the elbow entrance, on the inner radius of the bend. Additional simulations were performed for the same conditions, but with the RNG k-e model replaced by either the standard k-{var_epsilon}, or the realizable k-{var_epsilon} turbulence model. The predictions using the standard k-{var_epsilon} model are quite similar to those obtained in the baseline simulation. However, with the realizable k-{var_epsilon} model, more significant differences are evident. The maximums in both wall shear stress and turbulent kinetic energy now appear on the outer radius, near the elbow exit, and are {approx}11% and 14% greater, respectively, than those predicted in the baseline calculation; secondary maxima in both quantities still occur near the elbow entrance on the inner radius. Which set of results better reflects reality must await experimental corroboration. Additional calculations demonstrate that whether or not FLUENT's radial equilibrium pressure distribution option is used in the PRESSURE OUTLET boundary condition has no significant impact on the flowfield near the elbow. Simulations performed with and without the chemical sensor and associated support bracket that were present in the experiments demonstrate that the latter have a negligible influence on the flow in the vicinity of the elbow. The fact that the maxima in wall shear stress and turbulent kinetic energy occur on the inner radius is therefore not an artifact of having introduced the sensor into the flow.« less

Effect of aorto-iliac bifurcation and iliac stenosis on flow dynamics in an abdominal aortic aneurysm

NASA Astrophysics Data System (ADS)

Patel, Shivam; Usmani, Abdullah Y.; Muralidhar, K.

2017-06-01

Physiological flows in rigid diseased arterial flow phantoms emulating an abdominal aortic aneurysm (AAA) under rest conditions with aorto-iliac bifurcation and iliac stenosis are examined in vitro through 2D PIV measurements. Flow characteristics are first established in the model resembling a symmetric AAA with a straight outlet tube. The influence of aorto-iliac bifurcation and iliac stenosis on AAA flow dynamics is then explored through a comparison of the nature of flow patterns, vorticity evolution, vortex core trajectory and hemodynamic factors against the reference configuration. Specifically, wall shear stress and oscillatory shear index in the bulge portion of the models are of interest. The results of this investigation indicate overall phenomenological similarity in AAA flow patterns across the models. The pattern is characterized by a central jet and wall-bounded vortices whose strength increases during the deceleration phase as it moves forward. The central jet impacts the wall of AAA at its distal end. In the presence of an aorto-iliac bifurcation as well as iliac stenosis, the flow patterns show diminished strength, expanse and speed of propagation of the primary vortices. The positions of the instantaneous vortex cores, determined using the Q-function, correlate with flow separation in the bulge, flow resistance due to a bifurcation, and the break in symmetry introduced by a stenosis in one of the legs of the model. Time-averaged WSS in a healthy aorta is around 0.70 N m-2 and is lowered to the range ±0.2 N m-2 in the presence of the downstream bifurcation with a stenosed common iliac artery. The consequence of changes in the flow pattern within the aneurysm on disease progression is discussed.

Characteristics of time-varying intracranial pressure on blood flow through cerebral artery: A fluid-structure interaction approach.

PubMed

Syed, Hasson; Unnikrishnan, Vinu U; Olcmen, Semih

2016-02-01

Elevated intracranial pressure is a major contributor to morbidity and mortality in severe head injuries. Wall shear stresses in the artery can be affected by increased intracranial pressures and may lead to the formation of cerebral aneurysms. Earlier research on cerebral arteries and aneurysms involves using constant mean intracranial pressure values. Recent advancements in intracranial pressure monitoring techniques have led to measurement of the intracranial pressure waveform. By incorporating a time-varying intracranial pressure waveform in place of constant intracranial pressures in the analysis of cerebral arteries helps in understanding their effects on arterial deformation and wall shear stress. To date, such a robust computational study on the effect of increasing intracranial pressures on the cerebral arterial wall has not been attempted to the best of our knowledge. In this work, fully coupled fluid-structure interaction simulations are carried out to investigate the effect of the variation in intracranial pressure waveforms on the cerebral arterial wall. Three different time-varying intracranial pressure waveforms and three constant intracranial pressure profiles acting on the cerebral arterial wall are analyzed and compared with specified inlet velocity and outlet pressure conditions. It has been found that the arterial wall experiences deformation depending on the time-varying intracranial pressure waveforms, while the wall shear stress changes at peak systole for all the intracranial pressure profiles. © IMechE 2015.

Numerical analysis of the effect of turbulence transition on the hemodynamic parameters in human coronary arteries.

PubMed

Mahalingam, Arun; Gawandalkar, Udhav Ulhas; Kini, Girish; Buradi, Abdulrajak; Araki, Tadashi; Ikeda, Nobutaka; Nicolaides, Andrew; Laird, John R; Saba, Luca; Suri, Jasjit S

2016-06-01

Local hemodynamics plays an important role in atherogenesis and the progression of coronary atherosclerosis disease (CAD). The primary biological effect due to blood turbulence is the change in wall shear stress (WSS) on the endothelial cell membrane, while the local oscillatory nature of the blood flow affects the physiological changes in the coronary artery. In coronary arteries, the blood flow Reynolds number ranges from few tens to several hundreds and hence it is generally assumed to be laminar while calculating the WSS calculations. However, the pulsatile blood flow through coronary arteries under stenotic condition could result in transition from laminar to turbulent flow condition. In the present work, the onset of turbulent transition during pulsatile flow through coronary arteries for varying degree of stenosis (i.e., 0%, 30%, 50% and 70%) is quantitatively analyzed by calculating the turbulent parameters distal to the stenosis. Also, the effect of turbulence transition on hemodynamic parameters such as WSS and oscillatory shear index (OSI) for varying degree of stenosis is quantified. The validated transitional shear stress transport (SST) k-ω model used in the present investigation is the best suited Reynolds averaged Navier-Stokes turbulence model to capture the turbulent transition. The arterial wall is assumed to be rigid and the dynamic curvature effect due to myocardial contraction on the blood flow has been neglected. Our observations shows that for stenosis 50% and above, the WSSavg, WSSmax and OSI calculated using turbulence model deviates from laminar by more than 10% and the flow disturbances seems to significantly increase only after 70% stenosis. Our model shows reliability and completely validated. Blood flow through stenosed coronary arteries seems to be turbulent in nature for area stenosis above 70% and the transition to turbulent flow begins from 50% stenosis.

A displacement-pressure finite element formulation for analyzing the sound transmission in ducted shear flows with finite poroelastic lining.

PubMed

Nennig, Benoit; Tahar, Mabrouk Ben; Perrey-Debain, Emmanuel

2011-07-01

In the present work, the propagation of sound in a lined duct containing sheared mean flow is studied. Walls of the duct are acoustically treated with absorbent poroelastic foams. The propagation of elasto-acoustic waves in the liner is described by Biot's model. In the fluid domain, the propagation of sound in a sheared mean flow is governed by the Galbrun's equation. The problem is solved using a mixed displacement-pressure finite element formulation in both domains. A 3D implementation of the model has been performed and is illustrated on axisymmetric examples. Convergence and accuracy of the numerical model are shown for the particular case of the modal propagation in a infinite duct containing a uniform flow. Practical examples concerning the sound attenuation through dissipative silencers are discussed. In particular, effects of the refraction effects in the shear layer as well as the mounting conditions of the foam on the transmission loss are shown. The presence of a perforate screen at the air-porous interface is also considered and included in the model. © 2011 Acoustical Society of America

Turbulent structures of non-Newtonian solutions containing rigid polymers

NASA Astrophysics Data System (ADS)

Mohammadtabar, M.; Sanders, R. S.; Ghaemi, S.

2017-10-01

The turbulent structure of a channel flow of Xanthan Gum (XG) polymer solution is experimentally investigated and compared with water flow at a Reynolds number of Re = 7200 (based on channel height and properties of water) and Reτ = 220 (based on channel height and friction velocity, uτ0). The polymer concentration is varied from 75, 100, and 125 ppm to reach the point of maximum drag reduction (MDR). Measurements are carried out using high-resolution, two-component Particle Image Velocimetry (PIV) to capture the inner and outer layer turbulence. The measurements showed that the logarithmic layer shifts away from the wall with increasing polymer concentration. The slopes of the mean velocity profile for flows containing 100 and 125 ppm XG are greater than that measured for XG at 75 ppm, which is parallel with the slope obtained for deionized water. The increase in slope results in thickening buffer layer. At MDR, the streamwise Reynolds stresses are as large as those of the Newtonian flow while the wall-normal Reynolds stresses and Reynolds shear stresses are significantly attenuated. The sweep-dominated region in the immediate vicinity of the wall extends further from the wall with increasing polymer concentration. The near-wall skewness intensifies towards positive streamwise fluctuations and covers a larger wall-normal length at larger drag reduction values. The quadrant analysis at y + 0 = 25 shows that the addition of polymers inclines the principal axis of v versus u plot to almost zero (horizontal) as the joint probability density function of fluctuations becomes symmetric with respect to the u axis at MDR. The reduction of turbulence production is mainly associated with the attenuation of the ejection motions. The spatial-correlation of the fluctuating velocity field shows that increasing the polymer concentration increases the spatial coherence of u fluctuations in the streamwise direction while they appear to have the opposite effect in the wall-normal direction. The proper orthogonal decomposition of velocity fluctuations shows that the inclined shear layer structure of Newtonian wall flows becomes horizontal at the MDR and does not contribute to turbulence production.

Drag reduction in a turbulent channel flow using a passivity-based approach

NASA Astrophysics Data System (ADS)

Heins, Peter; Jones, Bryn; Sharma, Atul

2013-11-01

A new active feedback control strategy for attenuating perturbation energy in a turbulent channel flow is presented. Using a passivity-based approach, a controller synthesis procedure has been devised which is capable of making the linear dynamics of a channel flow as close to passive as is possible given the limitations on sensing and actuation. A controller that is capable of making the linearized flow passive is guaranteed to globally stabilize the true flow. The resulting controller is capable of greatly restricting the amount of turbulent energy that the nonlinearity can feed back into the flow. DNS testing of a controller using wall-sensing of streamwise and spanwise shear stress and actuation via wall transpiration acting upon channel flows with Reτ = 100 - 250 showed significant reductions in skin-friction drag.

Computation of turbulent boundary layers employing the defect wall-function method. M.S. Thesis

NASA Technical Reports Server (NTRS)

Brown, Douglas L.

1994-01-01

In order to decrease overall computational time requirements of spatially-marching parabolized Navier-Stokes finite-difference computer code when applied to turbulent fluid flow, a wall-function methodology, originally proposed by R. Barnwell, was implemented. This numerical effort increases computational speed and calculates reasonably accurate wall shear stress spatial distributions and boundary-layer profiles. Since the wall shear stress is analytically determined from the wall-function model, the computational grid near the wall is not required to spatially resolve the laminar-viscous sublayer. Consequently, a substantially increased computational integration step size is achieved resulting in a considerable decrease in net computational time. This wall-function technique is demonstrated for adiabatic flat plate test cases from Mach 2 to Mach 8. These test cases are analytically verified employing: (1) Eckert reference method solutions, (2) experimental turbulent boundary-layer data of Mabey, and (3) finite-difference computational code solutions with fully resolved laminar-viscous sublayers. Additionally, results have been obtained for two pressure-gradient cases: (1) an adiabatic expansion corner and (2) an adiabatic compression corner.

Computational analysis of microbubble flows in bifurcating airways: role of gravity, inertia, and surface tension.

PubMed

Chen, Xiaodong; Zielinski, Rachel; Ghadiali, Samir N

2014-10-01

Although mechanical ventilation is a life-saving therapy for patients with severe lung disorders, the microbubble flows generated during ventilation generate hydrodynamic stresses, including pressure and shear stress gradients, which damage the pulmonary epithelium. In this study, we used computational fluid dynamics to investigate how gravity, inertia, and surface tension influence both microbubble flow patterns in bifurcating airways and the magnitude/distribution of hydrodynamic stresses on the airway wall. Direct interface tracking and finite element techniques were used to simulate bubble propagation in a two-dimensional (2D) liquid-filled bifurcating airway. Computational solutions of the full incompressible Navier-Stokes equation were used to investigate how inertia, gravity, and surface tension forces as characterized by the Reynolds (Re), Bond (Bo), and Capillary (Ca) numbers influence pressure and shear stress gradients at the airway wall. Gravity had a significant impact on flow patterns and hydrodynamic stress magnitudes where Bo > 1 led to dramatic changes in bubble shape and increased pressure and shear stress gradients in the upper daughter airway. Interestingly, increased pressure gradients near the bifurcation point (i.e., carina) were only elevated during asymmetric bubble splitting. Although changes in pressure gradient magnitudes were generally more sensitive to Ca, under large Re conditions, both Re and Ca significantly altered the pressure gradient magnitude. We conclude that inertia, gravity, and surface tension can all have a significant impact on microbubble flow patterns and hydrodynamic stresses in bifurcating airways.

A High-Temperature MEMS Surface Fence for Wall-Shear-Stress Measurement in Scramjet Flow

PubMed Central

Ma, Binghe; Deng, Jinjun; Yuan, Weizheng; Zhou, Zitong; Zhang, Han

2017-01-01

A new variant of MEMS surface fence is proposed for shear-stress estimation under high-speed, high-temperature flow conditions. Investigation of high-temperature resistance including heat-resistant mechanism and process, in conjunction with high-temperature packaging design, enable the sensor to be used in environment up to 400 °C. The packaged sensor is calibrated over a range of ~65 Pa and then used to examine the development of the transient flow of the scramjet ignition process (Mach 2 airflow, stagnation pressure, and a temperature of 0.8 MPa and 950 K, respectively). The results show that the sensor is able to detect the transient flow conditions of the scramjet ignition process including shock impact, flow correction, steady state, and hydrogen off. PMID:29065498

A High-Temperature MEMS Surface Fence for Wall-Shear-Stress Measurement in Scramjet Flow.

PubMed

Ma, Chengyu; Ma, Binghe; Deng, Jinjun; Yuan, Weizheng; Zhou, Zitong; Zhang, Han

2017-10-22

A new variant of MEMS surface fence is proposed for shear-stress estimation under high-speed, high-temperature flow conditions. Investigation of high-temperature resistance including heat-resistant mechanism and process, in conjunction with high-temperature packaging design, enable the sensor to be used in environment up to 400 °C. The packaged sensor is calibrated over a range of ~65 Pa and then used to examine the development of the transient flow of the scramjet ignition process (Mach 2 airflow, stagnation pressure, and a temperature of 0.8 MPa and 950 K, respectively). The results show that the sensor is able to detect the transient flow conditions of the scramjet ignition process including shock impact, flow correction, steady state, and hydrogen off.

Clinical, morphological, and hemodynamic independent characteristic factors for rupture of posterior communicating artery aneurysms.

PubMed

Zhang, Ying; Jing, Linkai; Liu, Jian; Li, Chuanhui; Fan, Jixing; Wang, Shengzhang; Li, Haiyun; Yang, Xinjian

2016-08-01

To identify clinical, morphological, and hemodynamic independent characteristic factors that discriminate posterior communicating artery (PCoA) aneurysm rupture status. 173 patients with single PCoA aneurysms (108 ruptured, 65 unruptured) between January 2012 and June 2014 were retrospectively collected. Patient-specific models based on their three-dimensional digital subtraction angiography images were constructed and analyzed by a computational fluid dynamic method. All variables were analyzed by univariate analysis and multivariate logistic regression analysis. Two clinical factors (younger age and atherosclerosis), three morphological factors (higher aspect ratio, bifurcation type, and irregular shape), and six hemodynamic factors (lower mean and minimum wall shear stress, higher oscillatory shear index, a greater portion of area under low wall shear stress, unstable and complex flow pattern) were significantly associated with PCoA aneurysm rupture. Independent factors characterizing the rupture status were identified as age (OR 0.956, p=0.015), irregular shape (OR 6.709, p<0.001), and minimum wall shear stress (OR 0.001, p=0.038). We combined clinical, morphological, and hemodynamic characteristics analysis and found the three strongest independent factors for PCoA aneurysm rupture were younger age, irregular shape, and low minimum wall shear stress. This may be useful for guiding risk assessments and subsequent treatment decisions for PCoA aneurysms. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

Utility of Squeeze Flow in the Food Industry

NASA Astrophysics Data System (ADS)

Huang, T. A.

2008-07-01

Squeeze flow for obtaining shear viscosity on Newtonian and non-Newtonian fluids has long been established in the literature. Rotational shear flow using cone/plate, a set of parallel plates, or concentric cylinders all develop wall slip, shear fracture, or instability on food related materials such as peanut butter or mayonnaise. Viscosity data obtained using any one of the above mentioned set-ups is suspect or potentially results in significant error. They are unreliable to support or predict the textural differences perceived by consumer evaluation. RMS-800, from Rheometrics Inc., was employed to conduct the squeezing flow under constant speeds on a set of parallel plates. Viscosity data, over a broad range of shear rates, is compared between Hellmann's real (HRM) and light mayonnaise (HLM). The Consistency and shear-thinning indices, as defined in the Power-Law Model, were determined. HRM exhibits a more pronounced shear-thinning when compared to HLM yet the Consistency of HRM is significantly higher. Sensory evaluation by a trained expert panel ranked that adhesiveness and cohesiveness of HLM are significantly higher. It appears that the degree of shear thinning is one of the key rheological parameters in predicting the above mentioned difference in textural attributes. Error involved in determining viscosity from non-parallelism between two plates can be significant to affect the accuracy of the viscosity, in particular, shear-thinning index. Details are a subject for the next presentation. Nevertheless, the method is proven to be fast, rugged, simple, and reliable. It can be developed as a QC tool.

Drag reduction induced by superhydrophobic surfaces in turbulent pipe flow

NASA Astrophysics Data System (ADS)

Costantini, Roberta; Mollicone, Jean-Paul; Battista, Francesco

2018-02-01

The drag reduction induced by superhydrophobic surfaces is investigated in a turbulent pipe flow. Wetted superhydrophobic surfaces are shown to trap gas bubbles in their asperities. This stops the liquid from coming in direct contact with the wall in that location, allowing the flow to slip over the air bubbles. We consider a well-defined texture with streamwise grooves at the walls in which the gas is expected to be entrapped. This configuration is modeled with alternating no-slip and shear-free boundary conditions at the wall. With respect to the classical turbulent pipe flow, a substantial drag reduction is observed which strongly depends on the grooves' dimension and on the solid fraction, i.e., the ratio between the solid wall surface and the total surface of the pipe's circumference. The drag reduction is due to the mean slip velocity at the wall which increases the flow rate at a fixed pressure drop. The enforced boundary conditions also produce peculiar turbulent structures which on the contrary decrease the flow rate. The two concurrent effects provide an overall flow rate increase as demonstrated by means of the mean axial momentum balance. This equation provides the balance between the mean pressure gradient, the Reynolds stress, the mean flow rate, and the mean slip velocity contributions.

The effect of shear wall location in resisting earthquake

NASA Astrophysics Data System (ADS)

Tarigan, J.; Manggala, J.; Sitorus, T.

2018-02-01

Shear wall is one of lateral resisting structure which is used commonly. Shear wall gives high stiffness to the structure so as the structure will be stable. Applying shear wall can effectively reduce the displacement and story-drift of the structure. This will reduce the destruction comes from lateral loads such as an earthquake. Earlier studies showed that shear wall gives different performance based on its position in structures. In this paper, seismic analysis has been performed using response spectrum method for different Model of structures; they are the open frame, the shear wall at core symmetrically, the shear wall at periphery symmetrically, and the shear wall at periphery asymmetrically. The results are observed by comparing the displacement and story-drift. Based on the analysis, the placement of shear wall at the core of structure symmetrically gives the best performance to reduce the displacement and story-drift. It can reduce the displacement up to 61.16% (X-dir) and 70.60% (Y-dir). The placement of shear wall at periphery symmetrically will reduce the displacement up to 53.85% (X-dir) and 47.87% (Y-dir) while the placement of shear wall at periphery asymmetrically reducing the displacement up to 59.42% (X-dir) and 66.99% (Y-dir).

Long ligands reinforce biological adhesion under shear flow

NASA Astrophysics Data System (ADS)

Belyaev, Aleksey V.

2018-04-01

In this work, computer modeling has been used to show that longer ligands allow biological cells (e.g., blood platelets) to withstand stronger flows after their adhesion to solid walls. A mechanistic model of polymer-mediated ligand-receptor adhesion between a microparticle (cell) and a flat wall has been developed. The theoretical threshold between adherent and non-adherent regimes has been derived analytically and confirmed by simulations. These results lead to a deeper understanding of numerous biophysical processes, e.g., arterial thrombosis, and to the design of new biomimetic colloid-polymer systems.

Flexible Micropost Arrays for Shear Stress Measurement

NASA Technical Reports Server (NTRS)

Wohl, Christopher J.; Palmieri, Frank L.; Hopkins, John W.; Jackson, Allen M.; Connell, John W.; Lin, Yi; Cisotto, Alexxandra A.

2015-01-01

Increased fuel costs, heightened environmental protection requirements, and noise abatement continue to place drag reduction at the forefront of aerospace research priorities. Unfortunately, shortfalls still exist in the fundamental understanding of boundary-layer airflow over aerodynamic surfaces, especially regarding drag arising from skin friction. For example, there is insufficient availability of instrumentation to adequately characterize complex flows with strong pressure gradients, heat transfer, wall mass flux, three-dimensionality, separation, shock waves, and transient phenomena. One example is the acoustic liner efficacy on aircraft engine nacelle walls. Active measurement of shear stress in boundary layer airflow would enable a better understanding of how aircraft structure and flight dynamics affect skin friction. Current shear stress measurement techniques suffer from reliability, complexity, and airflow disruption, thereby compromising resultant shear stress data. The state-of-the-art for shear stress sensing uses indirect or direct measurement techniques. Indirect measurements (e.g., hot-wire, heat flux gages, oil interferometry, laser Doppler anemometry, small scale pressure drag surfaces, i.e., fences) require intricate knowledge of the studied flow, restrictive instrument arrangements, large surface areas, flow disruption, or seeding material; with smaller, higher bandwidth probes under development. Direct measurements involve strain displacement of a sensor element and require no prior knowledge of the flow. Unfortunately, conventional "floating" recessed components for direct measurements are mm to cm in size. Whispering gallery mode devices and Fiber Bragg Gratings are examples of recent additions to this type of sensor with much smaller (?m) sensor components. Direct detection techniques are often single point measurements and difficult to calibrate and implement in wind tunnel experiments. In addition, the wiring, packaging, and installation of delicate micro-electromechanical devices impede the use of most direct shear sensors. Similarly, the cavity required for sensing element displacement is sensitive to particulate obstruction. This work was focused on developing a shear stress sensor for use in subsonic wind tunnel test facilities applicable to an array of test configurations. The non-displacement shear sensors described here have minimal packaging requirements resulting in minimal or no disturbance of boundary layer flow. Compared to previous concepts, device installation could be simple with reduced cost and down-time. The novelty lies in the creation of low profile (nanoscale to 100 µm) micropost arrays that stay within the viscous sub-layer of the airflow. Aerodynamic forces, which are related to the surface shear stress, cause post deflection and optical property changes. Ultimately, a reliable, accurate shear stress sensor that does not disrupt the airflow has the potential to provide high value data for flow physics researchers, aerodynamicists, and aircraft manufacturers leading to greater flight efficiency arising from more in-depth knowledge on how aircraft design impacts near surface properties.

Use of thermoacoustic excitation for control of turbulent flow over a wall-mounted hump

NASA Astrophysics Data System (ADS)

Yeh, Chi-An; Munday, Phillip; Taira, Kunihiko

2014-11-01

We numerically examine the effectiveness of high-frequency acoustic excitation for drag reduction control of turbulent flow over a wall-mounted hump at a free stream Reynolds number of 500,000 and Mach number of 0.25. Actuation frequencies around Helmholtz number of 3 are considered based on the characteristics of recently developed graphene/carbon nanotube-based surface compliant loud speakers. The present study utilizes LES (CharLES) with an oscillatory heat flux boundary condition to produce high-intensity acoustic waves, which interact with the turbulent flow structures by introducing small-scale perturbations to the shear layer in the wake of the hump. With thermoacoustic control, the recirculation zone downstream of the hump becomes elongated with thinner shear layer profile compared to the uncontrolled case. This change in the flow shifts the low-pressure region of the wake further downstream and results in reduction in drag by 10% for two-dimensional and 15% for three-dimensional flows. The influence of actuation frequency and amplitude is also examined. This work is supported by the US Army Research Office (W911NF-13-1-0062, W911NF-14-1-0224).

Uncertainty quantification of wall shear stress in intracranial aneurysms using a data-driven statistical model of systemic blood flow variability.

PubMed

Sarrami-Foroushani, Ali; Lassila, Toni; Gooya, Ali; Geers, Arjan J; Frangi, Alejandro F

2016-12-08

Adverse wall shear stress (WSS) patterns are known to play a key role in the localisation, formation, and progression of intracranial aneurysms (IAs). Complex region-specific and time-varying aneurysmal WSS patterns depend both on vascular morphology as well as on variable systemic flow conditions. Computational fluid dynamics (CFD) has been proposed for characterising WSS patterns in IAs; however, CFD simulations often rely on deterministic boundary conditions that are not representative of the actual variations in blood flow. We develop a data-driven statistical model of internal carotid artery (ICA) flow, which is used to generate a virtual population of waveforms used as inlet boundary conditions in CFD simulations. This allows the statistics of the resulting aneurysmal WSS distributions to be computed. It is observed that ICA waveform variations have limited influence on the time-averaged WSS (TAWSS) on the IA surface. In contrast, in regions where the flow is locally highly multidirectional, WSS directionality and harmonic content are strongly affected by the ICA flow waveform. As a consequence, we argue that the effect of blood flow variability should be explicitly considered in CFD-based IA rupture assessment to prevent confounding the conclusions. Copyright © 2016 Elsevier Ltd. All rights reserved.

Hemodynamic Study of Flow Remodeling Stent Graft for the Treatment of Highly Angulated Abdominal Aortic Aneurysm

PubMed Central

Yeow, Siang Lin; Leo, Hwa Liang

2016-01-01

This study investigates the effect of a novel flow remodeling stent graft (FRSG) on the hemodynamic characteristics in highly angulated abdominal aortic aneurysm based on computational fluid dynamics (CFD) approach. An idealized aortic aneurysm with varying aortic neck angulations was constructed and CFD simulations were performed on nonstented models and stented models with FRSG. The influence of FRSG intervention on the hemodynamic performance is analyzed and compared in terms of flow patterns, wall shear stress (WSS), and pressure distribution in the aneurysm. The findings showed that aortic neck angulations significantly influence the velocity flow field in nonstented models, with larger angulations shifting the mainstream blood flow towards the center of the aorta. By introducing FRSG treatment into the aneurysm, erratic flow recirculation pattern in the aneurysm sac diminishes while the average velocity magnitude in the aneurysm sac was reduced in the range of 39% to 53%. FRSG intervention protects the aneurysm against the impacts of high velocity concentrated flow and decreases wall shear stress by more than 50%. The simulation results highlighted that FRSG may effectively treat aneurysm with high aortic neck angulations via the mechanism of promoting thrombus formation and subsequently led to the resorption of the aneurysm. PMID:27247612

Wall Shear Stress Distribution in a Patient-Specific Cerebral Aneurysm Model using Reduced Order Modeling

NASA Astrophysics Data System (ADS)

Han, Suyue; Chang, Gary Han; Schirmer, Clemens; Modarres-Sadeghi, Yahya

2016-11-01

We construct a reduced-order model (ROM) to study the Wall Shear Stress (WSS) distributions in image-based patient-specific aneurysms models. The magnitude of WSS has been shown to be a critical factor in growth and rupture of human aneurysms. We start the process by running a training case using Computational Fluid Dynamics (CFD) simulation with time-varying flow parameters, such that these parameters cover the range of parameters of interest. The method of snapshot Proper Orthogonal Decomposition (POD) is utilized to construct the reduced-order bases using the training CFD simulation. The resulting ROM enables us to study the flow patterns and the WSS distributions over a range of system parameters computationally very efficiently with a relatively small number of modes. This enables comprehensive analysis of the model system across a range of physiological conditions without the need to re-compute the simulation for small changes in the system parameters.

Evaluation of dispersive mixing, extension rate and bubble size distribution using numerical simulation of a non-Newtonian fluid in a twin-screw mixer

NASA Astrophysics Data System (ADS)

Rathod, Maureen L.

Initially 3D FEM simulation of a simplified mixer was used to examine the effect of mixer configuration and operating conditions on dispersive mixing of a non-Newtonian fluid. Horizontal and vertical velocity magnitudes increased with increasing mixer speed, while maximum axial velocity and shear rate were greater with staggered paddles. In contrast, parallel paddles produced an area of efficient dispersive mixing between the center of the paddle and the barrel wall. This study was expanded to encompass the complete nine-paddle mixing section using power-law and Bird-Carreau fluid models. In the center of the mixer, simple shear flow was seen, corresponding with high [special character omitted]. Efficient dispersive mixing appeared near the barrel wall at all flow rates and near the barrel center with parallel paddles. Areas of backflow, improving fluid retention time, occurred with staggered paddles. The Bird-Carreau fluid showed greater influence of paddle motion under the same operating conditions due to the inelastic nature of the fluid. Shear-thinning behavior also resulted in greater maximum shear rate as shearing became easier with decreasing fluid viscosity. Shear rate distributions are frequently calculated, but extension rate calculations have not been made in a complex geometry since Debbaut and Crochet (1988) defined extension rate as the ratio of the third to the second invariant of the strain rate tensor. Extension rate was assumed to be negligible in most studies, but here extension rate is shown to be significant. It is possible to calculate maximum stable bubble diameter from capillary number if shear and extension rates in a flow field are known. Extension rate distributions were calculated for Newtonian and non-Newtonian fluids. High extension and shear rates were found in the intermeshing region. Extension is the major influence on critical capillary number and maximum stable bubble diameter, but when extension rate values are low shear rate has a larger impact. Examination of maximum stable bubble diameter through the mixer predicted areas of higher bubble dispersion based on flow type. This research has advanced simulation of non-Newtonian fluid and shown that direct calculation of extension rate is possible, demonstrating the effect of extension rate on bubble break-up.

Flow field and oscillatory shear stress in a tuning-fork-shaped model of the average human carotid bifurcation.

PubMed

Ding, Z; Wang, K; Li, J; Cong, X

2001-12-01

The oscillatory shear index (OSI) was developed based on the hypothesis that intimal hyperplasia was correlated with oscillatory shear stresses. However, the validity of the OSI was in question since the correlation between intimal thickness and the OSI at the side walls of the sinus in the Y-shaped model of the average human carotid bifurcation (Y-AHCB) was weak. The objectives of this paper are to examine whether the reason for the weak correlation lies in the deviation in geometry of Y-AHCB from real human carotid bifurcation, and whether this correlation is clearly improved in the tuning-fork-shaped model of the average human carotid bifurcation (TF-AHCB). The geometry of the TF-AHCB model was based on observation and statistical analysis of specimens from 74 cadavers. The flow fields in both models were studied and compared by using flow visualization methods under steady flow conditions and by using laser Doppler anemometer (LDA) under pulsatile flow conditions. The TF-shaped geometry leads to a more complex flow field than the Y-shaped geometry. This added complexity includes strengthened helical movements in the sinus, new flow separation zone, and directional changes in the secondary flow patterns. The results show that the OSI-values at the side walls of the sinus in the TF-shaped model were more than two times as large as those in the Y-shaped model. This study confirmed the stronger correlation between the OSI and intimal thickness in the tuning-fork geometry of human carotid bifurcation, and the TF-AHCB model is a significant improvement over the traditional Y-shaped model.

Experimental data and model for the turbulent boundary layer on a convex, curved surface

NASA Technical Reports Server (NTRS)

Gillis, J. C.; Johnson, J. P.; Moffat, R. J.; Kays, W. M.

1981-01-01

Experiments were performed to determine how boundary layer turbulence is affected by strong convex curvature. The data gathered on the behavior of the Reynolds stress suggested the formulation of a simple turbulence model. Data were taken on two separate facilities. Both rigs had flow from a flat surface, over a convex surface with 90 deg of turning and then onto a flat recovery surface. The geometry was adjusted so that, for both rigs, the pressure gradient along the test surface was zero. Two experiments were performed at delta/R approximately 0.10, and one at weaker curvature with delta/R approximately 0.05. Results show that after a sudden introduction of curvature the shear stress in the outer part of the boundary layer is sharply diminished and is even slightly negative near the edge. The wall shear also drops off quickly downstream. When the surface suddenly becomes flat again, the wall shear and shear stress profiles recover very slowly towards flat wall conditions. A simple turbulence model, which was based on the theory that the Prandtl mixing length in the outer layer should scale on the velocity gradient layer, was shown to account for the slow recovery.

[Endodontics in motion: new concepts, materials and techniques 3. The role of irrigants during root canal treatment].

PubMed

van der Sluis, L W M

2015-10-01

The aims of root canal irrigation are the chemical dissolution or disruption and the mechanical detachment of pulp tissue, dentin debris and smear layer (instrumentation products), microorganisms (planktonic or biofilm) and their products from the root canal wall, their removal out of the root canal system and their chemical dissolution or disruption. Each of the endodontic irrigation systems has its own irrigant flow characteristics, which should fulfill these aims. Without flow (convection), the irrigant would have to be distributed through diffusion. This process is slow and depends on temperature and concentration gradients. On the other hand, convection is a faster and more efficient transport mechanism. During irrigant flow, frictional forces will occur, for example between the irrigant and the root canal wall (wall shear stress). These frictional forces have a mechanical cleaning effect on the root canal wall. These frictional forces are the result of the flow characteristics related to the different irrigation systems.

Numerical Simulation of the Flow in Vascular Grafts for Surgical Applications

NASA Astrophysics Data System (ADS)

McGah, Patrick; Aliseda, Alberto

2009-11-01

Numerical simulation of the human blood vessels, is becoming an important tool in surgical planning and research. Accurate vascular simulations might grant physicians the predictive capability to perform pre-surgical planning. We focus our attention on the implantation of vascular grafts. The high rate of failure of this common vascular interaction is intimately related to the fluid mechanics in the affected region and the subsequent wall tissue remodeling. Here, we will present our current work in developing a methodology for the numerical simulation of vascular grafts which incorporates physiologically realistic geometries and flow boundary conditions. In particular, we seek to correlate the wall shear stress and its spatial (WSSG) and temporal (OSI) variability to wall remodeling as observed in patient specific longitudinal studies. The pulsatility (Remean= 800 , Repeak= 2000, Wo = 2) of the flow gives rise to additional fluid dynamics phenomena such as instability, flow separation, transition, and unsteadiness. Our goal is to describe and evaluate their effect on the wall physiology.

Visualization and Measurement of Flow in a Model Rotating-Wall Bioreactor

NASA Astrophysics Data System (ADS)

Brown, Jason B.; Neitzel, G. Paul

1997-11-01

Fluid shear has been observed to have an effect on the in vitro growth of mammalian cells and is expected to play a role in the in vitro development of aggregates of cells into tissue. The interactions between culture media and cell constructs within a circular Couette flow bioreactor with independently rotating cylinders are investigated in model studies using flow visualization. Particle-Image Velocimetry (PIV) is used to quantify the velocity field in a plane perpendicular to the vessel axis which contains a cell construct model. This velocity field is then used to compute the instantaneous shear field. Experiments show the path of the model cell construct is dependent on the rotation rates of the cylinders.

Mathematical Modeling of Intravascular Blood Coagulation under Wall Shear Stress

PubMed Central

Rukhlenko, Oleksii S.; Dudchenko, Olga A.; Zlobina, Ksenia E.; Guria, Georgy Th.

2015-01-01

Increased shear stress such as observed at local stenosis may cause drastic changes in the permeability of the vessel wall to procoagulants and thus initiate intravascular blood coagulation. In this paper we suggest a mathematical model to investigate how shear stress-induced permeability influences the thrombogenic potential of atherosclerotic plaques. Numerical analysis of the model reveals the existence of two hydrodynamic thresholds for activation of blood coagulation in the system and unveils typical scenarios of thrombus formation. The dependence of blood coagulation development on the intensity of blood flow, as well as on geometrical parameters of atherosclerotic plaque is described. Relevant parametric diagrams are drawn. The results suggest a previously unrecognized role of relatively small plaques (resulting in less than 50% of the lumen area reduction) in atherothrombosis and have important implications for the existing stenting guidelines. PMID:26222505

Hemodynamic analysis of intracranial aneurysms using phase-contrast magnetic resonance imaging and computational fluid dynamics

NASA Astrophysics Data System (ADS)

Zhao, Xuemei; Li, Rui; Chen, Yu; Sia, Sheau Fung; Li, Donghai; Zhang, Yu; Liu, Aihua

2017-04-01

Additional hemodynamic parameters are highly desirable in the clinical management of intracranial aneurysm rupture as static medical images cannot demonstrate the blood flow within aneurysms. There are two ways of obtaining the hemodynamic information—by phase-contrast magnetic resonance imaging (PCMRI) and computational fluid dynamics (CFD). In this paper, we compared PCMRI and CFD in the analysis of a stable patient's specific aneurysm. The results showed that PCMRI and CFD are in good agreement with each other. An additional CFD study of two stable and two ruptured aneurysms revealed that ruptured aneurysms have a higher statistical average blood velocity, wall shear stress, and oscillatory shear index (OSI) within the aneurysm sac compared to those of stable aneurysms. Furthermore, for ruptured aneurysms, the OSI divides the positive and negative wall shear stress divergence at the aneurysm sac.

Investigating bacteria-surface interactions with microfluidics and Digital Holographic Microscopy

NASA Astrophysics Data System (ADS)

Agarwal, Harsh; Barry, Michael; Stocker, Roman; Sheng, Jian

2009-11-01

Quantitative data of swimming characteristics of bacteria in the shear flow adjacent to a surface are crucial for understanding cell attachment and detachment, and thus biofilm formation. We combined microfluidics and holography to expose Escherichia coli AW405 to a carefully controlled flow environment and visualize their movement in three dimensions. We investigated wall shear rates up to 200 (1/s) and recorded holograms at 40X magnification and 15fps for several minutes. Three-dimensional locations and orientations of bacteria were extracted from numerically reconstructed images. We obtained thousands of 3D trajectories over a sample volume of 380x380x200 μm, with a resolution of 0.2 μm in the two in-plane directions and 1 μm in the out-of-plane direction. Preliminary results revealed a range of behaviors, including circular trajectories near surfaces and migration normal to the wall. We expect that ongoing analysis will provide robust statistics of wall effects on bacterial motility. Sponsored by NIH (1-R21-EB008844-01) and NSF (CBET-0844647, DBI-0852875)

Distinct endothelial phenotypes evoked by arterial waveforms derived from atherosclerosis-susceptible and -resistant regions of human vasculature

NASA Astrophysics Data System (ADS)

Dai, Guohao; Kaazempur-Mofrad, Mohammad R.; Natarajan, Sripriya; Zhang, Yuzhi; Vaughn, Saran; Blackman, Brett R.; Kamm, Roger D.; García-Cardeña, Guillermo; Gimbrone, Michael A., Jr.

2004-10-01

Atherosclerotic lesion localization to regions of disturbed flow within certain arterial geometries, in humans and experimental animals, suggests an important role for local hemodynamic forces in atherogenesis. To explore how endothelial cells (EC) acquire functional/dysfunctional phenotypes in response to vascular region-specific flow patterns, we have used an in vitro dynamic flow system to accurately reproduce arterial shear stress waveforms on cultured human EC and have examined the effects on EC gene expression by using a high-throughput transcriptional profiling approach. The flow patterns in the carotid artery bifurcations of several normal human subjects were characterized by using 3D flow analysis based on actual vascular geometries and blood flow profiles. Two prototypic arterial waveforms, "athero-prone" and "athero-protective," were defined as representative of the wall shear stresses in two distinct regions of the carotid artery (carotid sinus and distal internal carotid artery) that are typically "susceptible" or "resistant," respectively, to atherosclerotic lesion development. These two waveforms were applied to cultured EC, and cDNA microarrays were used to analyze the differential patterns of EC gene expression. In addition, the differential effects of athero-prone vs. athero-protective waveforms were further characterized on several parameters of EC structure and function, including actin cytoskeletal organization, expression and localization of junctional proteins, activation of the NF-B transcriptional pathway, and expression of proinflammatory cytokines and adhesion molecules. These global gene expression patterns and functional data reveal a distinct phenotypic modulation in response to the wall shear stresses present in atherosclerosis-susceptible vs. atherosclerosis-resistant human arterial geometries.

Destabilizing turbulence in pipe flow

NASA Astrophysics Data System (ADS)

Kühnen, Jakob; Song, Baofang; Scarselli, Davide; Budanur, Nazmi Burak; Riedl, Michael; Willis, Ashley P.; Avila, Marc; Hof, Björn

2018-04-01

Turbulence is the major cause of friction losses in transport processes and it is responsible for a drastic drag increase in flows over bounding surfaces. While much effort is invested into developing ways to control and reduce turbulence intensities1-3, so far no methods exist to altogether eliminate turbulence if velocities are sufficiently large. We demonstrate for pipe flow that appropriate distortions to the velocity profile lead to a complete collapse of turbulence and subsequently friction losses are reduced by as much as 90%. Counterintuitively, the return to laminar motion is accomplished by initially increasing turbulence intensities or by transiently amplifying wall shear. Since neither the Reynolds number nor the shear stresses decrease (the latter often increase), these measures are not indicative of turbulence collapse. Instead, an amplification mechanism4,5 measuring the interaction between eddies and the mean shear is found to set a threshold below which turbulence is suppressed beyond recovery.

Particle-wall tribology of slippery hydrogel particle suspensions.

PubMed

Shewan, Heather M; Stokes, Jason R; Cloitre, Michel

2017-03-08

Slip is an important phenomenon that occurs during the flow of yield stress fluids like soft materials and pastes. Densely packed suspensions of hydrogel microparticles are used to show that slip is governed by the tribological interactions occurring between the samples and shearing surfaces. Both attractive/repulsive interactions between the dispersed particles and surface, as well as the viscoelasticity of the suspension, are found to play key roles in slip occurring within rheometric flows. We specifically discover that for two completely different sets of microgels, the sliding stress at which slip occurs scales with both the modulus of the particles and the bulk suspension modulus. This suggests that hysteresis losses within the viscoelastic particles contribute to friction forces and thus slip at the particle-surface tribo-contact. It is also found that slip during large amplitude oscillatory shear and steady shear flows share the same generic features.

Fluid mechanics of human fetal right ventricles from image-based computational fluid dynamics using 4D clinical ultrasound scans.

PubMed

Wiputra, Hadi; Lai, Chang Quan; Lim, Guat Ling; Heng, Joel Jia Wei; Guo, Lan; Soomar, Sanah Merchant; Leo, Hwa Liang; Biwas, Arijit; Mattar, Citra Nurfarah Zaini; Yap, Choon Hwai

2016-12-01

There are 0.6-1.9% of US children who were born with congenital heart malformations. Clinical and animal studies suggest that abnormal blood flow forces might play a role in causing these malformation, highlighting the importance of understanding the fetal cardiovascular fluid mechanics. We performed computational fluid dynamics simulations of the right ventricles, based on four-dimensional ultrasound scans of three 20-wk-old normal human fetuses, to characterize their flow and energy dynamics. Peak intraventricular pressure gradients were found to be 0.2-0.9 mmHg during systole, and 0.1-0.2 mmHg during diastole. Diastolic wall shear stresses were found to be around 1 Pa, which could elevate to 2-4 Pa during systole in the outflow tract. Fetal right ventricles have complex flow patterns featuring two interacting diastolic vortex rings, formed during diastolic E wave and A wave. These rings persisted through the end of systole and elevated wall shear stresses in their proximity. They were observed to conserve ∼25.0% of peak diastolic kinetic energy to be carried over into the subsequent systole. However, this carried-over kinetic energy did not significantly alter the work done by the heart for ejection. Thus, while diastolic vortexes played a significant role in determining spatial patterns and magnitudes of diastolic wall shear stresses, they did not have significant influence on systolic ejection. Our results can serve as a baseline for future comparison with diseased hearts. Copyright © 2016 the American Physiological Society.

Computational modeling of venous sinus stenosis in idiopathic intracranial hypertension

PubMed Central

Levitt, Michael R; McGah, Patrick M; Moon, Karam; Albuquerque, Felipe C; McDougall, Cameron G; Kalani, M Yashar S; Kim, Louis J; Aliseda, Alberto

2016-01-01

Background and Purpose Idiopathic intracranial hypertension has been associated with dural venous sinus stenosis in some patients, but the hemodynamic environment of the dural venous sinuses has not been quantitatively described. Here, we present the first such computational fluid dynamics model using patient-specific blood pressure measurements. Materials and Methods Six patients with idiopathic intracranial hypertension and at least one stenosis or atresia at the transverse-sigmoid sinus junction underwent MRV followed by cerebral venography and manometry throughout the dural venous sinuses. Patient-specific computational fluid dynamics models were created using MRV anatomy, with venous pressure measurements as boundary conditions. Blood flow and wall shear stress were calculated for each patient. Results Computational models of dural venous sinuses were successfully reconstructed in all six patients with patient-specific boundary conditions. Three patients demonstrated a pathologic pressure gradient (≥ 8 mm Hg) across four dural venous sinus stenoses. Small sample size precludes statistical comparisons, but average overall flow throughout the dural venous sinuses of patients with pathologic pressure gradients was higher than in those without (1041.00 ± 506.52 vs. 358.00 ± 190.95 mL/min). Wall shear stress was also higher across stenoses in patients with pathologic pressure gradients (37.66 ± 48.39 vs 7.02 ± 13.60 Pa). Conclusion The hemodynamic environment of the dural venous sinuses can be computationally modeled using patient-specific anatomy and physiological measurements in patients with idiopathic intracranial hypertension. There was substantially higher blood flow and wall shear stress in patients with pathological pressure gradients. PMID:27197986

Numerical study of nonequilibrium gas flow in a microchannel with a ratchet surface.

PubMed

Zhu, Lianhua; Guo, Zhaoli

2017-02-01

The nonequilibrium gas flow in a two-dimensional microchannel with a ratchet surface and a moving wall is investigated numerically with a kinetic method [Guo et al., Phys. Rev. E 91, 033313 (2015)]PLEEE81539-375510.1103/PhysRevE.91.033313. The presence of periodic asymmetrical ratchet structures on the bottom wall of the channel and the temperature difference between the walls of the channel result in a thermally induced flow, and hence a tangential propelling force on the wall. Such thermally induced propelling mechanism can be utilized as a model heat engine. In this article, the relations between the propelling force and the top wall moving velocity are obtained by solving the Boltzmann equation with the Shakhov model deterministically in a wide range of Knudsen numbers. The flow fields at both the static wall state and the critical state at which the thermally induced force cancels the drag force due to the active motion of the top wall are analyzed. A counterintuitive relation between the flow direction and the shear force is observed in the highly rarefied condition. The output power and thermal efficiency of the system working as a model heat engine are analyzed based on the momentum and energy transfer between the walls. The effects of Knudsen number, temperature difference, and geometric configurations are investigated. Guidance for improving the mechanical performance is discussed.

Nonlinear flow affects hydrodynamic forces and neutrophil adhesion rates in cone-plate viscometers.

PubMed Central

Shankaran, H; Neelamegham, S

2001-01-01

We present a theoretical and experimental analysis of the effects of nonlinear flow in a cone-plate viscometer. The analysis predicts that flow in the viscometer is a function of two parameters, the Reynolds number and the cone angle. Nonlinear flow occurs at high shear rates and causes spatial variations in wall shear stress, collision frequency, interparticle forces and attachment times within the viscometer. We examined the effect of these features on cellular adhesion kinetics. Based on recent data (Taylor, A. D., S. Neelamegham, J. D. Hellums, et al. 1996. Biophys. J. 71:3488-3500), we modeled neutrophil homotypic aggregation as a process that is integrin-limited at low shear and selectin-limited at high shear. Our calculations suggest that selectin and integrin on-rates lie in the order of 10(-2)-10(-4)/s. They also indicate that secondary flow causes positional variations in adhesion efficiency in the viscometer, and that the overall efficiency is dependent not only on the shear rate, but also the sample volume and the cone angle. Experiments performed with isolated neutrophils confirmed these predictions. In these experiments, enhancing secondary flow by increasing the sample volume from 100 to 1000 microl at 1500/s for a 2 degrees cone caused up to an approximately 45% drop in adhesion efficiency. Our results suggest that secondary flow may significantly influence cellular aggregation, platelet activation, and endothelial cell mechanotransduction measurements made in the viscometer over the range of conditions applied in typical biological studies. PMID:11371440

Significance of Shear Wall in Multi-Storey Structure With Seismic Analysis

NASA Astrophysics Data System (ADS)

Bongilwar, Rajat; Harne, V. R.; Chopade, Aditya

2018-03-01

In past decades, shear walls are one of the most appropriate and important structural component in multi-storied building. Therefore, it would be very interesting to study the structural response and their systems in multi-storied structure. Shear walls contribute the stiffness and strength during earthquakes which are often neglected during design of structure and construction. This study shows the effect of shear walls which significantly affect the vulnerability of structures. In order to test this hypothesis, G+8 storey building was considered with and without shear walls and analyzed for various parameters like base shear, storey drift ratio, lateral displacement, bending moment and shear force. Significance of shear wall has been studied with the help of two models. First model is without shear wall i.e. bare frame and other another model is with shear wall considering opening also in it. For modeling and analysis of both the models, FEM based software ETABS 2016 were used. The analysis of all models was done using Equivalent static method. The comparison of results has been done based on same parameters like base shear, storey drift ratio, lateral displacement, bending moment and shear force.

Steel Shear Walls, Behavior, Modeling and Design

NASA Astrophysics Data System (ADS)

Astaneh-Asl, Abolhassan

2008-07-01

In recent years steel shear walls have become one of the more efficient lateral load resisting systems in tall buildings. The basic steel shear wall system consists of a steel plate welded to boundary steel columns and boundary steel beams. In some cases the boundary columns have been concrete-filled steel tubes. Seismic behavior of steel shear wall systems during actual earthquakes and based on laboratory cyclic tests indicates that the systems are quite ductile and can be designed in an economical way to have sufficient stiffness, strength, ductility and energy dissipation capacity to resist seismic effects of strong earthquakes. This paper, after summarizing the past research, presents the results of two tests of an innovative steel shear wall system where the boundary elements are concrete-filled tubes. Then, a review of currently available analytical models of steel shear walls is provided with a discussion of capabilities and limitations of each model. We have observed that the tension only "strip model", forming the basis of the current AISC seismic design provisions for steel shear walls, is not capable of predicting the behavior of steel shear walls with length-to-thickness ratio less than about 600 which is the range most common in buildings. The main reasons for such shortcomings of the AISC seismic design provisions for steel shear walls is that it ignores the compression field in the shear walls, which can be significant in typical shear walls. The AISC method also is not capable of incorporating stresses in the shear wall due to overturning moments. A more rational seismic design procedure for design of shear walls proposed in 2000 by the author is summarized in the paper. The design method, based on procedures used for design of steel plate girders, takes into account both tension and compression stress fields and is applicable to all values of length-to-thickness ratios of steel shear walls. The method is also capable of including the effect of overturning moments and any normal forces that might act on the steel shear wall.

Hemodynamically driven stent strut design.

PubMed

Jiménez, Juan M; Davies, Peter F

2009-08-01

Stents are deployed to physically reopen stenotic regions of arteries and to restore blood flow. However, inflammation and localized stent thrombosis remain a risk for all current commercial stent designs. Computational fluid dynamics results predict that nonstreamlined stent struts deployed at the arterial surface in contact with flowing blood, regardless of the strut height, promote the creation of proximal and distal flow conditions that are characterized by flow recirculation, low flow (shear) rates, and prolonged particle residence time. Furthermore, low shear rates yield an environment less conducive for endothelialization, while local flow recirculation zones can serve as micro-reaction chambers where procoagulant and pro-inflammatory elements from the blood and vessel wall accumulate. By merging aerodynamic theory with local hemodynamic conditions we propose a streamlined stent strut design that promotes the development of a local flow field free of recirculation zones, which is predicted to inhibit thrombosis and is more conducive for endothelialization.

The steady inhomogeneous rapid granular shear flow of nearly elastic spheres

NASA Astrophysics Data System (ADS)

Chou, Chuen-Shii

2000-11-01

The steady inhomogeneous rapid granular shear flows of identical, smooth, nearly elastic spheres were considered, which interact with a flat wall to which identical, evenly spaced half-spheres have been attached. The boundary-value problem for the steady inhomogeneous shear flows, which are maintained by the relative motion of parallel bumpy boundaries, was solved by employing the constitutive relations of Jenkins and Richman (Arch. Rational Mech. Anal. 87 (1985) 355) and the boundary conditions of Richman (Acta. Mech. 75 (1988) 227) in the balance equations for mean fields of mass density of flow, velocity, and the granular temperature. How the resulting profiles of velocity, solid fraction, and granular temperature were affected by changes in the geometrical configuration of the boundary and the coefficient of restitution was demonstrated. Additionally, predicting how the slip velocity would vary with the geometrical configuration of the boundary, the coefficient of restitution, the flow depth and the average solid fraction within the flow was under taken. Special emphasis was placed on the manner in which the shear and normal stresses vary with boundary characteristics and the coefficient of restitution, primarily because the stresses are the quantities most easily measured by the experimentalist. Variations in slip velocity were observed to be partially responsible for the corresponding variations in the stresses.

Turbulent kinetic energy equation and free mixing

NASA Technical Reports Server (NTRS)

Morel, T.; Torda, T. P.; Bradshaw, P.

1973-01-01

Calculation of free shear flows was carried out to investigate the usefulness of several concepts which were previously successfully applied to wall flows. The method belongs to the class of differential approaches. The turbulence is taken into account by the introduction of one additional partial differential equation, the transport equation for the turbulent shear stress. The structure of turbulence is modeled after Bradshaw et al. This model was used successfully in boundary layers and its applicability to other flows is demonstrated. The work reported differs substantially from that of an earlier attempt to use this approach for calculation of free flows. The most important difference is that the region around the center line is treated by invoking the interaction hypothesis (concerning the structure of turbulence in the regions separated by the velocity extrema). The compressibility effects on shear layer spreading at low and moderate Mach numbers were investigated. In the absence of detailed experiments in free flows, the evidence from boundary layers that at low Mach numbers the structure of turbulence is unaffected by the compressibility was relied on. The present model was tested over a range of self-preserving and developing flows including pressure gradients using identical empirical input. The dependence of the structure of turbulence on the spreading rate of the shear layer was established.

Nonisotropic turbulence: A turbulent boundary layer

NASA Astrophysics Data System (ADS)

Liu, Kunlun

2005-11-01

The probability density function (PDF) and the two-point correlations of a flat-plate turbulent boundary layer subjected to the zero pressure gradient have been calculated by the direct numerical simulation. It is known that the strong shear force near the wall will deform the vortices and develop some stretched coherent structures like streaks and hairpins, which eventually cause the nonisotropy of wall shear flows. The PDF and the two-point correlations of isotropic flows have been studied for a long time. However, our knowledge about the influence of shear force on the PDF and two-point correlations is still very limited. This study is intended to investigate such influence by using a numerical simulation. Results are presented for a case having a Mach number of M=0.1 and a Reynolds number 2000, based on displacement thickness. The results indicate that the PDF of the streamwise velocity is Lognormal, the PDF of normal velocity is approximately Cauchy, and the PDF of the spanwise velocity is nearly Gaussian. The mean and variance of those PDFs vary according to the distance from the wall. And the two-point correlations are homogenous in the spanwise direction, have a slightly variation in the streamwise direction, but change a lot in the normal direction. Rww or Rvv can be represented as elliptic balls. And the well-chosen normalized system can enable Rww and Rvv to be self-similar.

Characterization of Fuego for laminar and turbulent natural convection heat transfer.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Francis, Nicholas Donald, Jr.; .)

2005-08-01

A computational fluid dynamics (CFD) analysis is conducted for internal natural convection heat transfer using the low Mach number code Fuego. The flow conditions under investigation are primarily laminar, transitional, or low-intensity level turbulent flows. In the case of turbulent boundary layers at low-level turbulence or transitional Reynolds numbers, the use of standard wall functions no longer applies, in general, for wall-bounded flows. One must integrate all the way to the wall in order to account for gradients in the dependent variables in the viscous sublayer. Fuego provides two turbulence models in which resolution of the near-wall region is appropriate.more » These models are the v2-f turbulence model and a Launder-Sharma, low-Reynolds number turbulence model. Two standard geometries are considered: the annulus formed between horizontal concentric cylinders and a square enclosure. Each geometry emphasizes wall shear flow and complexities associated with turbulent or near turbulent boundary layers in contact with a motionless core fluid. Overall, the Fuego simulations for both laminar and turbulent flows compared well to measured data, for both geometries under investigation, and to a widely accepted commercial CFD code (FLUENT).« less

Nobody knew turbulent transition could be so complicated

NASA Astrophysics Data System (ADS)

Barkley, Dwight

2017-11-01

Explaining the route to turbulence in wall-bounded shear flows has been a long and tortuous journey. After years of missteps, controversies, and uncertainties, we are at last converging on a unified and fascinating picture of transition in flows such as pipes, channels, and ducts. Classically, subcritical transition (such as in a pipe), was thought to imply a discontinuous route to turbulence. We now know that this is not the case - subcritical shear flows may, and often do, exhibit continuous transition. I will discuss recent developments in experiments, simulations, and theory that have established a deep connection between transition in subcritical shear flows and a class of non-equilibrium statistical phase transitions known as directed percolation. From this we understand how to define precise critical points for systems without linear instabilities and how to characterize the onset of turbulence in terms of non-trivial, but universal power laws. I will discuss the physics responsible for the complex turbulent structures ubiquitously observed near transition and end with thoughts on outstanding open questions.

Studying Turbulence Using Numerical Simulation Databases. Part 6; Proceedings of the 1996 Summer Program

NASA Technical Reports Server (NTRS)

1996-01-01

Topics considered include: New approach to turbulence modeling; Second moment closure analysis of the backstep flow database; Prediction of the backflow and recovery regions in the backward facing step at various Reynolds numbers; Turbulent flame propagation in partially premixed flames; Ensemble averaged dynamic modeling. Also included a study of the turbulence structures of wall-bounded shear flows; Simulation and modeling of the elliptic streamline flow.

On multiple solutions of non-Newtonian Carreau fluid flow over an inclined shrinking sheet

NASA Astrophysics Data System (ADS)

Khan, Masood; Sardar, Humara; Gulzar, M. Mudassar; Alshomrani, Ali Saleh

2018-03-01

This paper presents the multiple solutions of a non-Newtonian Carreau fluid flow over a nonlinear inclined shrinking surface in presence of infinite shear rate viscosity. The governing boundary layer equations are derived for the Carreau fluid with infinite shear rate viscosity. The suitable transformations are employed to alter the leading partial differential equations to a set of ordinary differential equations. The consequential non-linear ODEs are solved numerically by an active numerical approach namely Runge-Kutta Fehlberg fourth-fifth order method accompanied by shooting technique. Multiple solutions are presented graphically and results are shown for various physical parameters. It is important to state that the velocity and momentum boundary layer thickness reduce with increasing viscosity ratio parameter in shear thickening fluid while opposite trend is observed for shear thinning fluid. Another important observation is that the wall shear stress is significantly decreased by the viscosity ratio parameter β∗ for the first solution and opposite trend is observed for the second solution.

Transitional boundary layer in low-Prandtl-number convection at high Rayleigh number

NASA Astrophysics Data System (ADS)

Schumacher, Joerg; Bandaru, Vinodh; Pandey, Ambrish; Scheel, Janet

2016-11-01

The boundary layer structure of the velocity and temperature fields in turbulent Rayleigh-Bénard flows in closed cylindrical cells of unit aspect ratio is revisited from a transitional and turbulent viscous boundary layer perspective. When the Rayleigh number is large enough the boundary layer dynamics at the bottom and top plates can be separated into an impact region of downwelling plumes, an ejection region of upwelling plumes and an interior region (away from side walls) that is dominated by a shear flow of varying orientation. This interior plate region is compared here to classical wall-bounded shear flows. The working fluid is liquid mercury or liquid gallium at a Prandtl number of Pr = 0 . 021 for a range of Rayleigh numbers of 3 ×105 <= Ra <= 4 ×108 . The momentum transfer response to these system parameters generates a fluid flow in the closed cell with a macroscopic flow Reynolds number that takes values in the range of 1 . 8 ×103 <= Re <= 4 . 6 ×104 . It is shown that particularly the viscous boundary layers for the largest Ra are highly transitional and obey some properties that are directly comparable to transitional channel flows at friction Reynolds numbers below 100. This work is supported by the Deutsche Forschungsgemeinschaft.

Vascular wall flow-induced forces in a progressively enlarged aneurysm model.

PubMed

Neofytou, Panagiotis; Tsangaris, Sokrates; Kyriakidis, Michalis

2008-12-01

The current study is focused on the numerical investigation of the flow field induced by the unsteady flow in the vicinity of an abdominal aortic aneurysm model. The computational fluid dynamics code used is based on the finite volume method, and it has already been used in various bioflow studies. For modelling the rheological behaviour of blood, the Quemada non-Newtonian model is employed, which is suitable for simulating the two-phase character of blood namely a suspension of blood cells in plasma. For examining its non-Newtonian effects a comparison with a corresponding Newtonian flow is carried out. Furthermore, the investigation is focused on the distribution of the flow-induced forces on the interior wall of the aneurysm and in order to study the development of the distribution with the gradual enlargement of the aneurysm, three different degrees of aneurysm-growth have been assumed. Finally and for examining the effect of the distribution on the aneurysm growth, a comparison is made between the pressure and wall shear-stress distributions at the wall for each growth-degree.

Non-Newtonian fluid flow over a heterogeneously slippery surface

NASA Astrophysics Data System (ADS)

Haase, A. Sander; Wood, Jeffery A.; Sprakel, Lisette M. J.; Lammertink, Rob G. H.

2015-11-01

The no-slip boundary condition does not always hold. In the past, we have investigated the influence of effective wall slip on interfacial transport for a bubble mattress - a superhydrophobic surface consisting of an array of transverse gas-filled grooves. We proved experimentally that the amount of effective wall slip depends on the bubble protrusion angle and the surface porosity (Karatay et al., PNAS 110, 2013), and predicted that mass transport can be enhanced significantly (Haase et al., Soft Matter 9, 2013). Both studies involve the flow of water. In practise, however, many liquids encountered are non-Newtonian, like blood and polymer solutions. This raises some interesting questions. How does interfacial transport depend on the rheological properties of the liquid? Does the time-scale of the experiment matter? A bubble mattress is a suitable platform to investigate this, due to local variations in shear rate. We predict that for shear-thinning liquids, compared to water, the amount of wall slip can be enhanced considerably, although this depends on the applied flow rate. Experiments are performed to proof this behaviour. Simulations are used to assess what will happen when the characteristic time-scale of the system matches the relaxation time of the visco-elastic liquid. R.G.H.L. acknowledges the European Research Council for the ERC starting grant 307342-TRAM.

Vortex dynamics and wall shear stress behaviour associated with an elliptic jet impinging upon a flat plate

NASA Astrophysics Data System (ADS)

Long, J.; New, T. H.

2016-07-01

Vortical structures and dynamics of a Re h = 2100 elliptic jet impinging upon a flat plate were studied at H/ d h = 1, 2 and 4 jet-to-plate separation distances. Flow investigations were conducted along both its major and minor planes using laser-induced fluorescence and digital particle image velocimetry techniques. Results show that the impingement process along the major plane largely consists of primary jet ring-vortex and wall-separated secondary vortex formations, where they subsequently separate from the flat plate at smaller H/ d h = 1 and 2 separation distances. Key vortex formation locations occur closer to the impingement point as the separation distance increases. Interestingly, braid vortices and rib structures begin to take part in the impingement process at H/ d h = 4 and wave instabilities dominate the flow field. In contrast, significantly more coherent primary and secondary vortices with physically larger vortex core sizes and higher vortex strengths are observed along the minor plane, with no signs of braid vortices and rib structures. Lastly, influences of these different flow dynamics on the major and minor plane instantaneous and mean skin friction coefficient levels are investigated to shed light on the effects of separation distance on the wall shear stress distributions.

Analysis of temporal shear stress gradients during the onset phase of flow over a backward-facing step.

PubMed

Haidekker, M A; White, C R; Frangos, J A

2001-10-01

Endothelial cells in blood vessels are exposed to bloodflow and thus fluid shear stress. In arterial bifurcations and stenoses, disturbed flow causes zones of recirculation and stagnation, which are associated with both spatial and temporal gradients of shear stress. Such gradients have been linked to the generation of atherosclerotic plaques. For in-vitro studies of endothelial cell responses, the sudden-expansion flow chamber has been widely used and described. A two-dimensional numerical simulation of the onset phase of flow through the chamber was performed. The wall shear stress action on the bottom plate was computed as a function of time and distance from the sudden expansion. The results showed that depending on the time for the flow to be established, significant temporal gradients occurred close to the second stagnation point of flow. Slowly ramping the flow over 15 s instead of 200 ms reduces the temporal gradients by a factor of 300, while spatial gradients are reduced by 23 percent. Thus, the effects of spatial and temporal gradients can be observed separately. In experiments on endothelial cells, disturbed flow stimulated cell proliferation only when flow onset was sudden. The spatial patterns of proliferation rate match the exposure to temporal gradients. This study provides information on the dynamics of spatial and temporal gradients to which the cells are exposed in a sudden-expansion flow chamber and relates them to changes in the onset phase of flow.

Flow visualization study of the horseshoe vortex in a turbine stator cascade

NASA Technical Reports Server (NTRS)

Gaugler, R. E.; Russell, L. M.

1982-01-01

Flow visualization techniques were used to show the behavior of the horseshoe vortex in a large scale turbine stator cascade. Oil drops on the end wall surface flowed in response to local shear stresses, indicating the limiting flow streamlines at the surface. Smoke injected into the flow and photographed showed time averaged flow behavior. Neutrally bouyant helium filled soap bubbles followed the flow and showed up on photographs as streaks, indicating the paths followed by individual fluid particles. Preliminary attempts to control the vortex were made by injecting air through control jets drilled in the end wall near the vane leading edge. Seventeen different hole locations were tested, one at a time, and the effect of the control jets on the path follwed by smoke in the boundary layer was recorded photographically.

Fenestral pore size in the internal elastic lamina affects transmural flow distribution in the artery wall.

PubMed

Tada, S; Tarbell, J M

2001-06-01

Interstitial flow through the subendothelial intima and media of an artery wall was simulated numerically to investigate the water flow distribution through fenestral pores which affects the wall shear stress on smooth muscle cells right beneath the internal elastic lamina (IEL). A two-dimensional analysis using the Brinkman model of porous media flow was performed. It was observed that the hydraulic permeability of the intimal layer should be much greater than that of the media in order to predict a reasonable magnitude for the pressure drop across the subendothelial intima and IEL (about 23 mostly at a 70 mm Hg luminal pressure). When Ki was set equal to the value in the media, this pressure drop was unrealistically high. Furthermore, the higher value of Ki produced a nearly uniform distribution of water flow through a simple array of fenestral pores all having the same diameters (1.2 microm), whereas when Ki was set at the value in the media, the flow distribution through fenestral pores was highly nonuniform and nonphysiologic. A deformable intima model predicted a nonuniform flow distribution at high pressure (180 mm Hg). Damage to the IEL was simulated by introducing a large fenestral pore (up to 17.8 microm) into the array. A dramatic increase in flow through the large pore was observed implying an altered fluid mechanical environment on the smooth muscle cells near the large pore which has implications for intimal hyperplasia and atherosclerosis. The model also predicted that the fluid shear stress on the bottom surface of an endothelial cell is on the order of 10 dyne/cm2, a level which can affect cell function.

Constitutive model development for flows of granular materials

NASA Astrophysics Data System (ADS)

Chialvo, Sebastian

Granular flows are ubiquitous in both natural and industrial processes. When com- posed of dry, noncohesive particles, they manifest three different flow regimes---commonly referred to as the quasistatic, inertial, and intermediate regimes---each of which exhibits its own dependences on solids volume fraction, shear rate, and particle-level properties. The differences in these regimes can be attributed to microscale phenomena, with quasistatic flows being dominated by enduring, frictional contacts between grains, inertial flows by grain collisions, and intermediate flows by a combination of the two. Existing constitutive models for the solids-phase stress tend to focus on one or two regimes at a time, with a limited degree of success; the same is true of models for wall-boundary conditions for granular flows. Moreover, these models tend not to be based on detailed particle-level flow data, either from experiment or simulation. Clearly, a comprehensive modeling framework is lacking. The work in this thesis aims to address these issues by proposing continuum models constructed on the basis of discrete element method (DEM) simulations of granular shear flows. Specifically, we propose (a) a constitutive stress model that bridges the three dense flow regimes, (b) an modified kinetic-theory model that covers both the dense and dilute ends of the inertial regime, and (c) a boundary-condition model for dense, wall-bounded flows. These models facilitate the modeling of a wide range of flow systems of practical interest and provide ideas for further model development and refinement.

Numerical investigation of laminar forced convection in Newtonian and non-Newtonian flows in eccentric annuli

NASA Astrophysics Data System (ADS)

Fang, Pingping

1998-12-01

An extended numerical investigation of fully developed, forced convective laminar flows with heat transfer in eccentric annuli has been carried out. Both Newtonian and non-Newtonian (power-law or Ostwald-de Waele) fluids are studied, representing typical applications in petrochemical, bio-chemical, personal care products, polymer/plastic extrusion and food industries. For the heat transfer problem, with an insulated outer surface, two types of thermal boundary conditions have been considered: Constant wall temperature (T), and uniform axial heat flux with constant peripheral temperature (H1) on the inner surface of the annulus. The governing differential equations for momentum and energy conservation are solved by finite-difference methods. Velocity and temperature distributions in the flow cross section, the wall shear-stress distribution, and isothermal f Re, Nu i,T and Nu i,H1 values for different eccentric annuli (0/leɛ/*/le0.6,/ 0.2/le r/sp/*/le0.8) are presented. In Newtonian flows, the eccentricity is found to have a very strong influence on the flow and temperature fields. In an annulus with relatively large inner cylinder eccentricity, the flow tends to stagnate in the narrow section and has higher peak velocities in the wide section of the annulus. There is considerable flow maldistribution in the azimuthal direction, which in turn produces greater nonuniformity in the temperature field and a consequent degradation in the average heat transfer. Also, the H1 wall condition sustains higher heat transfer coefficients relative to the T boundary condition on the inner surface. For viscous, power-law type non-Newtonian flows, both shear thinning (n<1) and shear thickening (n>1) fluids are considered. Here, the non-linear shear behavior of the fluid is found to further aggravate the flow and temperature maldistribution, and once again the eccentricity is seen to exhibit a very strong influence on the friction and heat transfer behavior. Finally, the hydrodynamic characteristics of fully developed axial laminar flow of Newtonian fluids in eccentric annuli with a rotating inner cylinder are investigated. These are of significant importance to the design and operation of oil and gas drilling wells. Using finite-difference method to solve the governing flow equations in bipolar coordinates, computational results for a wide range of annulus geometry (0/le r/sp/*/le1,/ 0/le/varepsilon/sp/*/le0.8), and rotational Reynolds number (0/le Rer/le150) are presented, where the rotational speeds are restricted to the sub-critical Taylor number regime. The results delineate the effects of annuli r/sp/* and ɛsp/*, and inner cylinder rotation speed on the flow structure and frictional losses.

Bacterial adherence to graft tissues in static and flow conditions.

PubMed

Veloso, Tiago Rafael; Claes, Jorien; Van Kerckhoven, Soetkin; Ditkowski, Bartosz; Hurtado-Aguilar, Luis G; Jockenhoevel, Stefan; Mela, Petra; Jashari, Ramadan; Gewillig, Marc; Hoylaerts, Marc F; Meyns, Bart; Heying, Ruth

2018-01-01

Various conduits and stent-mounted valves are used as pulmonary valve graft tissues for right ventricular outflow tract reconstruction with good hemodynamic results. Valve replacement carries an increased risk of infective endocarditis (IE). Recent observations have increased awareness of the risk of IE after transcatheter implantation of a stent-mounted bovine jugular vein valve. This study focused on the susceptibility of graft tissue surfaces to bacterial adherence as a potential risk factor for subsequent IE. Adhesion of Staphylococcus aureus, Staphylococcus epidermidis, and Streptococcus sanguinis to bovine pericardium (BP) patch, bovine jugular vein (BJV), and cryopreserved homograft (CH) tissues was quantified under static and shear stress conditions. Microscopic analysis and histology were performed to evaluate bacterial adhesion to matrix components. In general, similar bacteria numbers were recovered from CH and BJV tissue surfaces for all strains, especially in flow conditions. Static bacterial adhesion to the CH wall was lower for S sanguinis adhesion (P < .05 vs BP patch). Adhesion to the BJV wall, CH wall, and leaflet was decreased for S epidermidis in static conditions (P < .05 vs BP patch). Bacterial adhesion under shear stress indicated similar bacterial adhesion to all tissues, except for lower adhesion to the BJV wall after S sanguinis incubation. Microscopic analysis showed the importance of matrix component exposure for bacterial adherence to CH. Our data provide evidence that the surface composition of BJV and CH tissues themselves, bacterial surface proteins, and shear forces per se are not the prime determinants of bacterial adherence. Copyright © 2017 The American Association for Thoracic Surgery. Published by Elsevier Inc. All rights reserved.

Seismic Performance of Composite Shear Walls Constructed Using Recycled Aggregate Concrete and Different Expandable Polystyrene Configurations.

PubMed

Liu, Wenchao; Cao, Wanlin; Zhang, Jianwei; Qiao, Qiyun; Ma, Heng

2016-03-02

The seismic performance of recycled aggregate concrete (RAC) composite shear walls with different expandable polystyrene (EPS) configurations was investigated. Six concrete shear walls were designed and tested under cyclic loading to evaluate the effect of fine RAC in designing earthquake-resistant structures. Three of the six specimens were used to construct mid-rise walls with a shear-span ratio of 1.5, and the other three specimens were used to construct low-rise walls with a shear-span ratio of 0.8. The mid-rise and low-rise shear walls consisted of an ordinary recycled concrete shear wall, a composite wall with fine aggregate concrete (FAC) protective layer (EPS modules as the external insulation layer), and a composite wall with sandwiched EPS modules as the insulation layer. Several parameters obtained from the experimental results were compared and analyzed, including the load-bearing capacity, stiffness, ductility, energy dissipation, and failure characteristics of the specimens. The calculation formula of load-bearing capacity was obtained by considering the effect of FAC on composite shear walls as the protective layer. The damage process of the specimen was simulated using the ABAQUS Software, and the results agreed quite well with those obtained from the experiments. The results show that the seismic resistance behavior of the EPS module composite for shear walls performed better than ordinary recycled concrete for shear walls. Shear walls with sandwiched EPS modules had a better seismic performance than those with EPS modules lying outside. Although the FAC protective layer slightly improved the seismic performance of the structure, it undoubtedly slowed down the speed of crack formation and the stiffness degradation of the walls.

Seismic Performance of Composite Shear Walls Constructed Using Recycled Aggregate Concrete and Different Expandable Polystyrene Configurations

PubMed Central

Liu, Wenchao; Cao, Wanlin; Zhang, Jianwei; Qiao, Qiyun; Ma, Heng

2016-01-01

The seismic performance of recycled aggregate concrete (RAC) composite shear walls with different expandable polystyrene (EPS) configurations was investigated. Six concrete shear walls were designed and tested under cyclic loading to evaluate the effect of fine RAC in designing earthquake-resistant structures. Three of the six specimens were used to construct mid-rise walls with a shear-span ratio of 1.5, and the other three specimens were used to construct low-rise walls with a shear-span ratio of 0.8. The mid-rise and low-rise shear walls consisted of an ordinary recycled concrete shear wall, a composite wall with fine aggregate concrete (FAC) protective layer (EPS modules as the external insulation layer), and a composite wall with sandwiched EPS modules as the insulation layer. Several parameters obtained from the experimental results were compared and analyzed, including the load-bearing capacity, stiffness, ductility, energy dissipation, and failure characteristics of the specimens. The calculation formula of load-bearing capacity was obtained by considering the effect of FAC on composite shear walls as the protective layer. The damage process of the specimen was simulated using the ABAQUS Software, and the results agreed quite well with those obtained from the experiments. The results show that the seismic resistance behavior of the EPS module composite for shear walls performed better than ordinary recycled concrete for shear walls. Shear walls with sandwiched EPS modules had a better seismic performance than those with EPS modules lying outside. Although the FAC protective layer slightly improved the seismic performance of the structure, it undoubtedly slowed down the speed of crack formation and the stiffness degradation of the walls. PMID:28773274

Morphotype-Dependent Flow Characteristics in Bicuspid Aortic Valve Ascending Aortas: A Benchtop Particle Image Velocimetry Study

PubMed Central

McNally, Andrew; Madan, Ashish; Sucosky, Philippe

2017-01-01

The bicuspid aortic valve (BAV) is a major risk factor for secondary aortopathy such as aortic dilation. The heterogeneous BAV morphotypes [left-right-coronary cusp fusion (LR), right-non-coronary cusp fusion (RN), and left-non-coronary cusp fusion (LN)] are associated with different dilation patterns, suggesting a role for hemodynamics in BAV aortopathogenesis. However, assessment of this theory is still hampered by the limited knowledge of the hemodynamic abnormalities generated by the distinct BAV morphotypes. The objective of this study was to compare experimentally the hemodynamics of a normal (i.e., non-dilated) ascending aorta (AA) subjected to tricuspid aortic valve (TAV), LR-BAV, RN-BAV, and NL-BAV flow. Tissue BAVs reconstructed from porcine TAVs were subjected to physiologic pulsatile flow conditions in a left-heart simulator featuring a realistic aortic root and compliant aorta. Phase-locked particle image velocimetry experiments were carried out to characterize the flow in the aortic root and in the tubular AA in terms of jet skewness and displacement, as well as mean velocity, viscous shear stress and Reynolds shear stress fields. While all three BAVs generated skewed and asymmetrical orifice jets (up to 1.7- and 4.0-fold increase in flow angle and displacement, respectively, relative to the TAV at the sinotubular junction), the RN-BAV jet was out of the plane of observation. The LR- and NL-BAV exhibited a 71% increase in peak-systolic orifice jet velocity relative to the TAV, suggesting an inherent degree of stenosis in BAVs. While these two BAV morphotypes subjected the convexity of the aortic wall to viscous shear stress overloads (1.7-fold increase in maximum peak-systolic viscous shear stress relative to the TAV-AA), the affected sites were morphotype-dependent (LR-BAV: proximal AA, NL-BAV: distal AA). Lastly, the LR- and NL-BAV generated high degrees of turbulence in the AA (up to 2.3-fold increase in peak-systolic Reynolds shear stress relative to the TAV) that were sustained from peak systole throughout the deceleration phase. This in vitro study reveals substantial flow abnormalities (increased jet skewness, asymmetry, jet velocity, turbulence, and shear stress overloads) in non-dilated BAV aortas, which differ from those observed in dilated aortas but still coincide with aortic wall regions prone to dilation. PMID:28203207

Two-Axis Direct Fluid Shear Stress Sensor for Aerodynamic Applications

NASA Technical Reports Server (NTRS)

Bajikar, Sateesh S.; Scott, Michael A.; Adcock, Edward E.

2011-01-01

This miniature or micro-sized semiconductor sensor design provides direct, nonintrusive measurement of skin friction or wall shear stress in fluid flow situations in a two-axis configuration. The sensor is fabricated by microelectromechanical system (MEMS) technology, enabling small size and multiple, low-cost reproductions. The sensors may be fabricated by bonding a sensing element wafer to a fluid-coupling element wafer. Using this layered machine structure provides a truly three-dimensional device.

Flow pattern analysis in a highly stenotic patient-specific carotid bifurcation model using a turbulence model.

PubMed

Li, Zhi-Yong; Tan, Felicia P P; Soloperto, Giulia; Wood, Nigel B; Xu, Xiao Y; Gillard, Jonathan H

2015-08-01

The aim of this study is to investigate the blood flow pattern in carotid bifurcation with a high degree of luminal stenosis, combining in vivo magnetic resonance imaging (MRI) and computational fluid dynamics (CFD). A newly developed two-equation transitional model was employed to evaluate wall shear stress (WSS) distribution and pressure drop across the stenosis, which are closely related to plaque vulnerability. A patient with an 80% left carotid stenosis was imaged using high resolution MRI, from which a patient-specific geometry was reconstructed and flow boundary conditions were acquired for CFD simulation. A transitional model was implemented to investigate the flow velocity and WSS distribution in the patient-specific model. The peak time-averaged WSS value of approximately 73 Pa was predicted by the transitional flow model, and the regions of high WSS occurred at the throat of the stenosis. High oscillatory shear index values up to 0.50 were present in a helical flow pattern from the outer wall of the internal carotid artery immediately after the throat. This study shows the potential suitability of a transitional turbulent flow model in capturing the flow phenomena in severely stenosed carotid arteries using patient-specific MRI data and provides the basis for further investigation of the links between haemodynamic variables and plaque vulnerability. It may be useful in the future for risk assessment of patients with carotid disease.

Hot film wall shear instrumentation for compressible boundary layer transition research

NASA Technical Reports Server (NTRS)

Schneider, Steven P.

1992-01-01

Experimental and analytical studies of hot film wall shear instrumentation were performed. A new hot film anemometer was developed and tested. The anemometer performance was not quite as good as that of commercial anemometers, but the cost was much less and testing flexibility was improved. The main focus of the project was a parametric study of the effect of sensor size and substrate material on the performance of hot film surface sensors. Both electronic and shock-induced flow experiments were performed to determine the sensitivity and frequency response of the sensors. The results are presented in Michael Moen's M.S. thesis, which is appended. A condensed form of the results was also submitted for publication.

Flow behaviour in normal and Meniere’s disease of endolymphatic fluid inside the inner ear

NASA Astrophysics Data System (ADS)

Paisal, Muhammad Sufyan Amir; Azmi Wahab, Muhamad; Taib, Ishkrizat; Mat Isa, Norasikin; Ramli, Yahaya; Seri, Suzairin Md; Darlis, Nofrizalidris; Osman, Kahar; Khudzari, Ahmad Zahran Md; Nordin, Normayati

2017-09-01

Meniere’s disease is a rare disorder that affects the inner ear which might be more severe if not treated. This is due to fluctuating pressure of the fluid in the endolymphatic sac and dysfunction of cochlea which causing the stretching of vestibular membrane. However, the pattern of the flow recirculation in endolymphatic region is still not fully understood. Thus, this study aims to investigate the correlation between the increasing volume of endolymphatic fluid and flow characteristics such as velocity, pressure and wall shear stress. Three dimensional model of simplified endolymphatic region is modeled using computer aided design (CAD) software and simulated using computational fluid dynamic (CFD) software. There are three different models are investigated; normal (N) model, Meniere’s disease model with less severity (M1) and Meniere’s disease model with high severity (M2). From the observed, the pressure drop between inlet and outlet of inner ear becomes decreases as the outlet pressure along with endolymphatic volume increases. However, constant flow rate imposed at the inlet of endolymphatic showing the lowest velocity. Flow recirculation near to endolymphatic region is occurred as the volume in endolympathic increases. Overall, high velocity is monitored near to cochlear duct, ductus reuniens and endolymphatic duct. Hence, these areas show high distributions of wall shear stress (WSS) that indicating a high probability of endolymphatic wall membrane dilation. Thus, more severe conditions of Meniere’s disease, more complex of flow characteristic is occurred. This phenomenon presenting high probability of rupture is predicted at the certain area in the anatomy of vestibular system.

Transient Droplet Behavior and Droplet Breakup during Bulk and Confined Shear Flow in Blends with One Viscoelastic Component: Experiments, Modelling and Simulations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cardinaels, Ruth; Verhulst, Kristof; Moldenaers, Paula

2008-07-07

The transient droplet deformation and droplet orientation after inception of shear, the shape relaxation after cessation of shear and droplet breakup during shear, are microscopically studied, both under bulk and confined conditions. The studied blends contain one viscoelastic Boger fluid phase. A counter rotating setup, based on a Paar Physica MCR300, is used for the droplet visualisation. For bulk shear flow, it is shown that the droplet deformation during startup of shear flow and the shape relaxation after cessation of shear flow are hardly influenced by droplet viscoelasticity, even at moderate to high capillary and Deborah numbers. The effects ofmore » droplet viscoelasticity only become visible close to the critical conditions and a novel break-up mechanism is observed. Matrix viscoelasticity has a more pronounced effect, causing overshoots in the deformation and significantly inhibiting relaxation. However, different applied capillary numbers prior to cessation of shear flow, with the Deborah number fixed, still result in a single master curve for shape retraction, as in fully Newtonian systems. The long tail in the droplet relaxation can be qualitatively described with a phenomenological model for droplet deformation, when using a 5-mode Giesekus model for the fluid rheology. It is found that the shear flow history significantly affects the droplet shape evolution and the breakup process in blends with one viscoelastic component. Confining a droplet between two plates accelerates the droplet deformation kinetics, similar to fully Newtonian systems. However, the increased droplet deformation, due to wall effects, causes the steady state to be reached at a later instant in time. Droplet relaxation is less sensitive to confinement, leading to slower relaxation kinetics only for highly confined droplets. For the blend with a viscoelastic droplet, a non-monotonous trend is found for the critical capillary number as a function of the confinement ratio. Finally, experimental data are compared with 3D simulations, performed with a volume-of-fluid algorithm.« less

A Study of Bubble and Slug Gas-Liquid Flow in a Microgravity Environment

NASA Technical Reports Server (NTRS)

McQuillen, J.

2000-01-01

The influence of gravity on the two-phase flow dynamics is obvious.As the gravity level is reduced,there is a new balance between inertial and interfacial forces, altering the behavior of the flow. In bubbly flow,the absence of drift velocity leads to spherical-shaped bubbles with a rectilinear trajectory.Slug flow is a succession of long bubbles and liquid slug carrying a few bubbles. There is no flow reversal in the thin liquid film as the long bubble and liquid slug pass over the film. Although the flow structure seems to be simpler than in normal gravity conditions,the models developed for the prediction of flow behavior in normal gravity and extended to reduced gravity flow are unable to predict the flow behavior correctly.An additional benefit of conducting studies in microgravity flows is that these studies aide the development of understanding for normal gravity flow behavior by removing the effects of buoyancy on the shape of the interface and density driven shear flows between the gas and the liquid phases. The proposal calls to study specifically the following: 1) The dynamics of isolated bubbles in microgravity liquid flows will be analyzed: Both the dynamics of spherical isolated bubbles and their dispersion by turbulence, their interaction with the pipe wall,the behavior of the bubbles in accelerated or decelerated flows,and the dynamics of isolated cylindrical bubbles, their deformation in accelerated/decelerated flows (in converging or diverging channels), and bubble/bubble interaction. Experiments will consist of the use of Particle Image Velocimetry (PIV) and Laser Doppler Velocimeters (LDV) to study single spherical bubble and single and two cylindrical bubble behavior with respect to their influence on the turbulence of the surrounding liquid and on the wall 2) The dynamics of bubbly and slug flow in microgravity will be analyzed especially for the role of the coalescence in the transition from bubbly to slug flow (effect of fluid properties and surfactant), to identify clusters that promote coalescence and transition the void fraction distribution in bubbly and slug flow,to measure the wall friction in bubbly flow. These experiments will consist of multiple bubbles type flows and will utilize hot wire and film anemometers to measure liquid velocity and wall shear stress respectively and double fiber optic probes to measure bubble size and velocity as a function of tube radius and axial location.

Asymptotic formulae for flow in superhydrophobic channels with longitudinal ridges and protruding menisci

NASA Astrophysics Data System (ADS)

Kirk, Toby L.

2018-03-01

This paper presents new analytical formulae for flow in a channel with one or both walls patterned with a longitudinal array of ridges and arbitrarily protruding menisci. Derived from a matched asymptotic expansion, they extend results by Crowdy (J. Fluid Mech., vol. 791, 2016, R7) for shear flow, and thus make no restriction on the protrusion into or out of the liquid. The slip length formula is compared against full numerical solutions and, despite the assumption of small ridge period in its derivation, is found to have a very large range of validity; relative errors are small even for periods large enough for the protruding menisci to degrade the flow and touch the opposing wall.

Heat transfer enhancement due to a longitudinal vortex produced by a single winglet in a pipe

DOE Office of Scientific and Technical Information (OSTI.GOV)

Oyakawa, Kenyu; Senaha, Izuru; Ishikawa, Shuji

1999-07-01

Longitudinal vortices were artificially generated by a single winglet vortex generator in a pipe. The purpose of this study is to analyze the motion of longitudinal vortices and their effects on heat transfer enhancement. The flow pattern was visualized by means of both fluorescein and rhodamine B as traces in a water flow. The main vortex was moved spirally along the circumference and the behavior of the other vortices was observed. Streamwise and circumferential heat transfer coefficients on the wall, wall static pressure, and velocity distribution in an overall cross section were also measured for the air flow in amore » range of Reynolds numbers from 18,800 to 62,400. The distributions of the streamwise heat transfer coefficient had a periodic pattern, and the peaks in the distribution were circumferentially moved due to the spiral motion of the main vortex. Lastly, the relationships between the iso-velocity distribution, wall static pressure, and heat transfer characteristics was shown. In the process of forming the vortex behind the winglet vortex generator, behaviors of both the main vortex and the corner vortex were observed as streak lines. The vortex being raised along the end of the winglet, and the vortex ring being rolled up to the main vortex were newly observed. Both patterns of the streamwise velocity on a cross-section and the static pressure on the wall show good correspondences to phenomena of the main vortex spirally flowing downstream. The increased ratio of the heat transfer is similar to that of the friction factor based on the shear stress on the wall surface of the pipe. The quantitative analogy between the heat transfer and the shear stress is confirmed except for some regions, where the effects of the down-wash or blow-away of the secondary flows is caused due to the main vortex.« less

Code and Solution Verification of 3D Numerical Modeling of Flow in the Gust Erosion Chamber

NASA Astrophysics Data System (ADS)

Yuen, A.; Bombardelli, F. A.

2014-12-01

Erosion microcosms are devices commonly used to investigate the erosion and transport characteristics of sediments at the bed of rivers, lakes, or estuaries. In order to understand the results these devices provide, the bed shear stress and flow field need to be accurately described. In this research, the UMCES Gust Erosion Microcosm System (U-GEMS) is numerically modeled using Finite Volume Method. The primary aims are to simulate the bed shear stress distribution at the surface of the sediment core/bottom of the microcosm, and to validate the U-GEMS produces uniform bed shear stress at the bottom of the microcosm. The mathematical model equations are solved by on a Cartesian non-uniform grid. Multiple numerical runs were developed with different input conditions and configurations. Prior to developing the U-GEMS model, the General Moving Objects (GMO) model and different momentum algorithms in the code were verified. Code verification of these solvers was done via simulating the flow inside the top wall driven square cavity on different mesh sizes to obtain order of convergence. The GMO model was used to simulate the top wall in the top wall driven square cavity as well as the rotating disk in the U-GEMS. Components simulated with the GMO model were rigid bodies that could have any type of motion. In addition cross-verification was conducted as results were compared with numerical results by Ghia et al. (1982), and good agreement was found. Next, CFD results were validated by simulating the flow within the conventional microcosm system without suction and injection. Good agreement was found when the experimental results by Khalili et al. (2008) were compared. After the ability of the CFD solver was proved through the above code verification steps. The model was utilized to simulate the U-GEMS. The solution was verified via classic mesh convergence study on four consecutive mesh sizes, in addition to that Grid Convergence Index (GCI) was calculated and based on that the computation uncertainty was quantified. The numerical results reveal that the bed shear stress distribution for the U-GEMS model was not uniform. The mean and standard deviation of the bed shear stress for the U-GEMS model was 0.04 and 0.019 Pa respectively.

Large-eddy simulations of the restricted nonlinear system

NASA Astrophysics Data System (ADS)

Bretheim, Joel; Gayme, Dennice; Meneveau, Charles

2014-11-01

Wall-bounded shear flows often exhibit elongated flow structures with streamwise coherence (e.g. rolls/streaks), prompting the exploration of a streamwise-constant modeling framework to investigate wall-turbulence. Simulations of a streamwise-constant (2D/3C) model have been shown to produce the roll/streak structures and accurately reproduce the blunted turbulent mean velocity profile in plane Couette flow. The related restricted nonlinear (RNL) model captures these same features but also exhibits self-sustaining turbulent behavior. Direct numerical simulation (DNS) of the RNL system results in similar statistics for a number of flow quantities and a flow field that is consistent with DNS of the Navier-Stokes equations. Aiming to develop reduced-order models of wall-bounded turbulence at very high Reynolds numbers in which viscous near-wall dynamics cannot be resolved, this work presents the development of an RNL formulation of the filtered Navier-Stokes equations solved for in large-eddy simulations (LES). The proposed LES-RNL system is a computationally affordable reduced-order modeling tool that is of interest for studying the underlying dynamics of high-Reynolds wall-turbulence and for engineering applications where the flow field is dominated by streamwise-coherent motions. This work is supported by NSF (IGERT, SEP-1230788 and IIA-1243482).

Effect of blood viscosity on oxygen transport in residual stenosed artery following angioplasty.

PubMed

Kwon, Ohwon; Krishnamoorthy, Mahesh; Cho, Young I; Sankovic, John M; Banerjee, Rupak K

2008-02-01

The effect of blood viscosity on oxygen transport in a stenosed coronary artery during the postangioplasty scenario is studied. In addition to incorporating varying blood viscosity using different hematocrit (Hct) concentrations, oxygen consumption by the avascular wall and its supply from vasa vasorum, nonlinear oxygen binding capacity of the hemoglobin, and basal to hyperemic flow rate changes are included in the calculation of oxygen transport in both the lumen and the avascular wall. The results of this study show that oxygen transport in the postangioplasty residual stenosed artery is affected by non-Newtonian shear-thinning property of the blood viscosity having variable Hct concentration. As Hct increases from 25% to 65%, the diminished recirculation zone for the increased Hct causes the commencement of pO(2) decrease to shift radially outward by approximately 20% from the center of the artery for the basal flow, but by approximately 10% for the hyperemic flow at the end of the diverging section. Oxygen concentration increases from a minimum value at the core of the recirculation zone to over 90 mm Hg before the lumen-wall interface at the diverging section for the hyperemic flow, which is attributed to increased shear rate and thinner lumen boundary layer for the hyperemic flow, and below 90 mm Hg for the basal flow. As Hct increases from 25% to 65%, the average of pO(2,min) beyond the diverging section drops by approximately 25% for the basal flow, whereas it increases by approximately 15% for the hyperemic flow. Thus, current results with the moderate stenosed artery indicate that reducing Hct might be favorable in terms of increasing O(2) flux and pO(2,min), in the medial region of the wall for the basal flow, while higher Hct is advantageous for the hyperemic flow beyond the diverging section. The results of this study not only provide significant details of oxygen transport under varying pathophysiologic blood conditions such as unusually high blood viscosity and flow rate, but might also be extended to offer implications for drug therapy related to blood-thinning medication and for blood transfusion and hemorrhage.

Hydrodynamic shear stress and mass transport modulation of endothelial cell metabolism.

PubMed

Nollert, M U; Diamond, S L; McIntire, L V

1991-09-01

Mammalian cells responds to physical forces by altering their growth rate, morphology, metabolism, and genetic expression. We have studied the mechanism by which these cells detect the presence of mechanical stress and convert this force into intracellular signals. As our model systems, we have studied cultured human endothelial cells, which line the blood vessels and forms the interface between the blood and the vessel wall. These cell responds within minutes to the initiation of flow by increasing their arachidonic acid metabolism and increasing the level of the intracellular second messengers inositol trisphosphate and calcium ion concentration. With continued exposure to arterial levels of wall shear stress for up to 24 h, endothelial cells increase the expression of tissue plasminogen activator (tPA) and tPA messenger RNA (mRNA) and decrease the expression of endothelin peptide and endothelin mRNA. Since the initiation of flow also causes enhanced convective mass transfer to the endothelial cell monolayer, we have investigated the role of enhanced convection of adenosine trisphosphate (ATP) to the cell surface in eliciting a cellular response by monitoring cytosolic calcium concentrations on the single cell level and by computing the concentration profile of ATP in a parallel-plate flow geometry. Our result demonstrate that endothelial cells respond in very specific ways to the initiation of flow and that mass transfer and fluid shear stress can both play a role in the modulation of intracellular signal transduction and metabolism.

Multiscale modeling and simulation of blood flow in coronary artery bypass graft surgeries

NASA Astrophysics Data System (ADS)

Sankaran, Sethuraman; Esmaily Moghadam, Mahdi; Kahn, Andy; Marsden, Alison

2011-11-01

We present a computational framework for modeling and simulation of blood flow in patients who undergo coronary artery bypass graft (CABG) surgeries. We evaluate the influence of shape on the homeostatic state, cardiac output, and other quantities of interest. We present a case study on a patient with multiple CABG. We build a patient-specific model of the blood vessels comprised of the aorta, vessels branching from the top of the aorta (brachiocephalic artery and carotids) and the coronary arteries, in addition to bypass grafts. The rest of the circulatory system is modeled using lumped parameter 0D models comprised of resistances, compliances, inertances and elastance. An algorithm is presented that computes these parameters automatically given constraints on the flow. A Finite element framework is used to compute blood flow and pressure in the 3D model to which the 0D code is coupled at the model inlets and outlets. An adaptive closed loop BC is used to capture the coupling of the various outlets of the model with inlets, and is compared with a model with fixed inlet BC. We compare and contrast the pressure, flowrate, coronary perfusion, and PV curves obtained in the different cases. Further, we compare and contrast quantities of interest such as wall shear stress, wall shear stress gradients and oscillatory shear index for different surgical geometries and discuss implications of patient-specific optimization. I would like to acknowlege AHA for funding this work.

DNS of Laminar-Turbulent Transition in Swept-Wing Boundary Layers

NASA Technical Reports Server (NTRS)

Duan, L.; Choudhari, M.; Li, F.

2014-01-01

Direct numerical simulation (DNS) is performed to examine laminar to turbulent transition due to high-frequency secondary instability of stationary crossflow vortices in a subsonic swept-wing boundary layer for a realistic natural-laminar-flow airfoil configuration. The secondary instability is introduced via inflow forcing and the mode selected for forcing corresponds to the most amplified secondary instability mode that, in this case, derives a majority of its growth from energy production mechanisms associated with the wall-normal shear of the stationary basic state. An inlet boundary condition is carefully designed to allow for accurate injection of instability wave modes and minimize acoustic reflections at numerical boundaries. Nonlinear parabolized stability equation (PSE) predictions compare well with the DNS in terms of modal amplitudes and modal shape during the strongly nonlinear phase of the secondary instability mode. During the transition process, the skin friction coefficient rises rather rapidly and the wall-shear distribution shows a sawtooth pattern that is analogous to the previously documented surface flow visualizations of transition due to stationary crossflow instability. Fully turbulent features are observed in the downstream region of the flow.

DBD Actuated Flow Control of Wall-Jet and Cross-Flow Interaction for Film Cooling Applications

NASA Astrophysics Data System (ADS)

Tirumala, Rakshit; Benard, Nicolas; Moreau, Eric; Fenot, Matthieu; Lalizel, Gildas; Dorignac, Eva

2014-11-01

In this work, we use surface DBD actuators to control the interaction between a wall jet and mainstream flow in film cooling applications. The intention of the study is to improve the contact of the jet with the wall and enhance the convective heat transfer coefficient downstream of the jet exit. A 2D wall jet (10 mm height) is injected into the mainstream flow at an angle of 30°. With an injected jet velocity (Ui) of 5 m/s, two blowing ratios M (=ρi Ui / ρ∞U∞) of 1.0 and 0.5 are studied corresponding to the mainstream flow velocity (U∞) of 5 m/s and 10 m/s respectively. Different configurations of the DBD actuator are studied, positioned both inside the jet and on the downstream side. PIV measurements are conducted to investigate the flow field of the interaction between the jet and cross flow. Streamwise velocity profiles at different downstream locations are compared to analyze the efficacy of the plasma actuator in improving the contact between the injected jet stream and the wall surface. Reynolds shear stress measurements are also conducted to study the mixing regions in the plasma-jet-mainstream flow interaction. Work was partially funded by the French government program ``Investissements d'avenir'' (LABEX INTERACTIFS, reference ANR-11-LABX-0017-01).

Linear and weakly nonlinear aspects of free shear layer instability, roll-up, subharmonic interaction and wall influence

NASA Technical Reports Server (NTRS)

Cain, A. B.; Thompson, M. W.

1986-01-01

The growth of the momentum thickness and the modal disturbance energies are examined to study the nature and onset of nonlinearity in a temporally growing free shear layer. A shooting technique is used to find solutions to the linearized eigenvalue problem, and pseudospectral weakly nonlinear simulations of this flow are obtained for comparison. The roll-up of a fundamental disturbance follows linear theory predictions even with a 20 percent disturbance amplitude. A weak nonlinear interaction of the disturbance creates a finite-amplitude mean shear stress which dominates the growth of the layer momentum thickness, and the disturbance growth rate changes until the fundamental disturbance dominates. The fundamental then becomes an energy source for the harmonic, resulting in an increase in the growth rate of the subharmonic over the linear prediction even when the fundamental has no energy to give. Also considered are phase relations and the wall influence.

Optimal energy growth in a stably stratified shear flow

NASA Astrophysics Data System (ADS)

Jose, Sharath; Roy, Anubhab; Bale, Rahul; Iyer, Krithika; Govindarajan, Rama

2018-02-01

Transient growth of perturbations by a linear non-modal evolution is studied here in a stably stratified bounded Couette flow. The density stratification is linear. Classical inviscid stability theory states that a parallel shear flow is stable to exponentially growing disturbances if the Richardson number (Ri) is greater than 1/4 everywhere in the flow. Experiments and numerical simulations at higher Ri show however that algebraically growing disturbances can lead to transient amplification. The complexity of a stably stratified shear flow stems from its ability to combine this transient amplification with propagating internal gravity waves (IGWs). The optimal perturbations associated with maximum energy amplification are numerically obtained at intermediate Reynolds numbers. It is shown that in this wall-bounded flow, the three-dimensional optimal perturbations are oblique, unlike in unstratified flow. A partitioning of energy into kinetic and potential helps in understanding the exchange of energies and how it modifies the transient growth. We show that the apportionment between potential and kinetic energy depends, in an interesting manner, on the Richardson number, and on time, as the transient growth proceeds from an optimal perturbation. The oft-quoted stabilizing role of stratification is also probed in the non-diffusive limit in the context of disturbance energy amplification.

Intraventricular Flow Velocity Vector Visualization Based on the Continuity Equation and Measurements of Vorticity and Wall Shear Stress

NASA Astrophysics Data System (ADS)

Itatani, Keiichi; Okada, Takashi; Uejima, Tokuhisa; Tanaka, Tomohiko; Ono, Minoru; Miyaji, Kagami; Takenaka, Katsu

2013-07-01

We have developed a system to estimate velocity vector fields inside the cardiac ventricle by echocardiography and to evaluate several flow dynamical parameters to assess the pathophysiology of cardiovascular diseases. A two-dimensional continuity equation was applied to color Doppler data using speckle tracking data as boundary conditions, and the velocity component perpendicular to the echo beam line was obtained. We determined the optimal smoothing method of the color Doppler data, and the 8-pixel standard deviation of the Gaussian filter provided vorticity without nonphysiological stripe shape noise. We also determined the weight function at the bilateral boundaries given by the speckle tracking data of the ventricle or vascular wall motion, and the weight function linear to the distance from the boundary provided accurate flow velocities not only inside the vortex flow but also around near-wall regions on the basis of the results of the validation of a digital phantom of a pipe flow model.

Identification of flow structures in fully developed canonical and wavy channels by means of modal decomposition techniques

NASA Astrophysics Data System (ADS)

Ghebali, Sacha; Garicano-Mena, Jesús; Ferrer, Esteban; Valero, Eusebio

2018-04-01

A Dynamic Mode Decomposition (DMD) of Direct Numerical Simulations (DNS) of fully developed channel flows is undertaken in order to study the main differences in flow features between a plane-channel flow and a passively “controlled” flow wherein the mean friction was reduced relative to the baseline by modifying the geometry in order to generate a streamwise-periodic spanwise pressure gradient, as is the case for an oblique wavy wall. The present analysis reports POD and DMD modes for the plane channel, jointly with the application of a sparsity-promoting method, as well as a reconstruction of the Reynolds shear stress with the dynamic modes. Additionally, a dynamic link between the streamwise velocity fluctuations and the friction on the wall is sought by means of a composite approach both in the plane and wavy cases. One of the DMD modes associated with the wavy-wall friction exhibits a meandering motion which was hardly identifiable on the instantaneous friction fluctuations.

Low-drag events in transitional wall-bounded turbulence

NASA Astrophysics Data System (ADS)

Whalley, Richard D.; Park, Jae Sung; Kushwaha, Anubhav; Dennis, David J. C.; Graham, Michael D.; Poole, Robert J.

2017-03-01

Intermittency of low-drag pointwise wall shear stress measurements within Newtonian turbulent channel flow at transitional Reynolds numbers (friction Reynolds numbers 70 - 130) is characterized using experiments and simulations. Conditional mean velocity profiles during low-drag events closely approach that of a recently discovered nonlinear traveling wave solution; both profiles are near the so-called maximum drag reduction profile, a general feature of turbulent flow of liquids containing polymer additives (despite the fact that all results presented are for Newtonian fluids only). Similarities between temporal intermittency in small domains and spatiotemporal intermittency in large domains is thereby found.

Turbulent flow near the wall of a conical diffuser

NASA Astrophysics Data System (ADS)

Satyaprakash, B. R.; Azad, R. S.; Nagabushana, K. A.; Kassab, S. Z.

The turbulent flow in a conical diffuser is predicted adapting the boundary layer calculation method of Bradshaw, Ferris and Atwell. The predicted mean velocity and shear stress profiles, using the experimental data as initial input, agree well with the measured profiles. The universal low of the wall present at the inlet vahishes in the initial region and reappears later, but the width of validity is diminished considerably. The effect of divergence is present in the initial region of the diffuser only. This technique fails to predict beyond one half the total length of the diffuser.

Causal analysis of self-sustaining processes in the logarithmic layer of wall-bounded turbulence

NASA Astrophysics Data System (ADS)

Bae, H. J.; Encinar, M. P.; Lozano-Durán, A.

2018-04-01

Despite the large amount of information provided by direct numerical simulations of turbulent flows, their underlying dynamics remain elusive even in the most simple and canonical configurations. Most common approaches to investigate the turbulence phenomena do not provide a clear causal inference between events, which is essential to determine the dynamics of self-sustaining processes. In the present work, we examine the causal interactions between streaks, rolls and mean shear in the logarithmic layer of a minimal turbulent channel flow. Causality between structures is assessed in a non-intrusive manner by transfer entropy, i.e., how much the uncertainty of one structure is reduced by knowing the past states of the others. We choose to represent streaks by the first Fourier modes of the streamwise velocity, while rolls are defined by the wall-normal and spanwise velocity modes. The results show that the process is mainly unidirectional rather than cyclic, and that the log-layer motions are sustained by extracting energy from the mean shear which controls the dynamics and time-scales. The well-known lift-up effect is also identified, but shown to be of secondary importance in the causal network between shear, streaks and rolls.

Laser interferometer skin-friction measurements of crossing-shock-wave/turbulent-boundary-layer interactions

NASA Technical Reports Server (NTRS)

Garrison, T. J.; Settles, G. S.; Narayanswami, N.; Knight, D. D.

1994-01-01

Wall shear stress measurements beneath crossing-shock-wave/turbulent boundary-layer interactions have been made for three interactions of different strengths. The interactions are generated by two sharp fins at symetric angles of attack mounted on a flat plate. The shear stress measurements were made for fin angles of 7 and 11 deg at Mach 3 and 15 deg at Mach 3.85. The measurements were made using a laser interferometer skin-friction meter, a device that determines the wall shear by optically measuring the time rate of thinning of an oil film placed on the test model surface. Results of the measurements reveal high skin-friction coefficients in the vicinity of the fin/plate junction and the presence of quasi-two-dimensional flow separation on the interaction center line. Additionally, two Navier-Stokes computations, one using a Baldwin-Lomax turbulence model and one using a k-epsilon model, are compared with the experimental results for the Mach 3.85, 15-deg interaction case. Although the k-epsilon model did a reasonable job of predicting the overall trend in portions of the skin-friction distribution, neither computation fully captured the physics of the near-surface flow in this complex interaction.

A numerical simulation of peristaltic motion in the ureter using fluid structure interactions.

PubMed

Vahidi, Bahman; Fatouraee, Nasser

2007-01-01

An axisymmetric model with fluid-structure interactions (FSI) is introduced and solved to perform ureter flow and stress analysis. The Navier-Stokes equations are solved for the fluid and a linear elastic model for ureter is used. The finite element equations for both the structure and the fluid were solved by the Newton-Raphson iterative method. Our results indicated that shear stresses were high around the throat of moving contracted wall. The pressure gradient magnitude along the ureter wall and the symmetry line had the maximum value around the throat of moving contracted wall which decreased as the peristalsis propagates toward the bladder. The flow rate at the ureter outlet at the end of the peristaltic motion was about 650 mm3/s. During propagation of the peristalsis toward the bladder, the inlet backward flow region was limited to the areas near symmetry line but the inner ureter backward flow regions extended to the whole ureter contraction part. The backward flow was vanished after 1.5 seconds of peristalsis propagation start up and after that time the urine flow was forward in the whole ureter length, so reflux is more probable to be present at the beginning of the wall peristaltic motion.

Effects of 8-week swimming training on carotid arterial stiffness and hemodynamics in young overweight adults.

PubMed

Yuan, Wen-Xue; Liu, Hai-Bin; Gao, Feng-Shan; Wang, Yan-Xia; Qin, Kai-Rong

2016-12-28

Exercise has been found to either reduce or increase arterial stiffness. Land-based exercise modalities have been documented as effective physical therapies to decrease arterial stiffness. However, these land-based exercise modalities may not be suitable for overweight individuals, in terms of risks of joint injury. The purpose of this study was to determine the effects of 8-week swimming training and 4-week detraining on carotid arterial stiffness and hemodynamics in young overweight adults. Twenty young male adults who were overweight were recruited and engaged in 8-week of swimming training and 4-week detraining. Five individuals withdrew due to lack of interest and failure to follow the training protocol. Body Fat Percentage (BFP) and carotid hemodynamic variables were measured on a resting day at the following intervals: baseline, 4 weeks, 8 weeks after swimming training and 4 weeks after detraining. A repeated analysis of variance (ANOVA) was used to assess the differences between baseline and each measurement. When significant differences were detected, Tukey's test for post hoc comparisons was used. Eight-week swimming training at moderate intensity decreased BFP, including the trunk and four extremities. Additionally, the BFP of the right and left lower extremities continued to decrease in these overweight adults 4 weeks after ceasing training. Carotid arterial stiffness decreased, while there were no significant changes in arterial diameters. Blood flow velocity, flow rate, maximal and mean wall shear stress increased, while systolic blood pressure and peripheral resistance decreased. No significant differences existed in minimal wall shear stress and oscillatory shear stress. Eight-week swimming training at moderate intensity exhibited beneficial effects on systolic blood pressure, arterial stiffness and blood supply to the brain in overweight adults. Moreover, maximal and mean wall shear stress increased after training. It is worth noting that these changes in hemodynamics did not last 4 weeks. Therefore, further studies are still warranted to clarify the underlying relationship between improvements in arterial stiffness and alterations in wall shear stress.

Inertial migration of particles in Taylor-Couette flows

NASA Astrophysics Data System (ADS)

Majji, Madhu V.; Morris, Jeffrey F.

2018-03-01

An experimental study of inertial migration of neutrally buoyant particles in the circular Couette flow (CCF), Taylor vortex flow (TVF) and wavy vortex flow (WVF) is reported. This work considers a concentric cylinder Taylor-Couette device with a stationary outer cylinder and rotating inner cylinder. The device has a radius ratio of η = ri/ro = 0.877, where ri and ro are the inner and outer radii of the flow annulus. The ratio of the annular width between the cylinders (δ = ro - ri) and the particle diameter (dp) is α = δ/dp = 20. For η = 0.877, the flow of a Newtonian fluid undergoes transitions from CCF to TVF and TVF to WVF at Reynolds numbers Re = 120 and 151, respectively, and for the dilute suspensions studied here, these critical Reynolds numbers are almost unchanged. In CCF, particles were observed to migrate, due to the competition between the shear gradient of the flow and the wall interactions, to an equilibrium location near the middle of the annulus with an offset toward the inner cylinder. In TVF, the vortex motion causes the particles to be exposed to the shear gradient and wall interactions in a different manner, resulting in a circular equilibrium region in each vortex. The radius of this circular region grows with increase in Re. In WVF, the azimuthal waviness results in fairly well-distributed particles across the annulus.

Analysis of cell flux in the parallel plate flow chamber: implications for cell capture studies.

PubMed Central

Munn, L L; Melder, R J; Jain, R K

1994-01-01

The parallel plate flow chamber provides a controlled environment for determinations of the shear stress at which cells in suspension can bind to endothelial cell monolayers. By decreasing the flow rate of cell-containing media over the monolayer and assessing the number of cells bound at each wall shear stress, the relationship between shear force and binding efficiency can be determined. The rate of binding should depend on the delivery of cells to the surface as well as the intrinsic cell-surface interactions; thus, only if the cell flux to the surface is known can the resulting binding curves be interpreted correctly. We present the development and validation of a mathematical model based on the sedimentation rate and velocity profile in the chamber for the delivery of cells from a flowing suspension to the chamber surface. Our results show that the flux depends on the bulk cell concentration, the distance from the entrance point, and the flow rate of the cell-containing medium. The model was then used in a normalization procedure for experiments in which T cells attach to TNF-alpha-stimulated HUVEC monolayers, showing that a threshold for adhesion occurs at a shear stress of about 3 dyn/cm2. Images FIGURE 1 FIGURE 2 PMID:7948702

Turbulent flows over superhydrophobic surfaces with shear-dependent slip length

NASA Astrophysics Data System (ADS)

Khosh Aghdam, Sohrab; Seddighi, Mehdi; Ricco, Pierre

2015-11-01

Motivated by recent experimental evidence, shear-dependent slip length superhydrophobic surfaces are studied. Lyapunov stability analysis is applied in a 3D turbulent channel flow and extended to the shear-dependent slip-length case. The feedback law extracted is recognized for the first time to coincide with the constant-slip-length model widely used in simulations of hydrophobic surfaces. The condition for the slip parameters is found to be consistent with the experimental data and with values from DNS. The theoretical approach by Fukagata (PoF 18.5: 051703) is employed to model the drag-reduction effect engendered by the shear-dependent slip-length surfaces. The estimated drag-reduction values are in very good agreement with our DNS data. For slip parameters and flow conditions which are potentially realizable in the lab, the maximum computed drag reduction reaches 50%. The power spent by the turbulent flow on the walls is computed, thereby recognizing the hydrophobic surfaces as a passive-absorbing drag-reduction method, as opposed to geometrically-modifying techniques that do not consume energy, e.g. riblets, hence named passive-neutral. The flow is investigated by visualizations, statistical analysis of vorticity and strain rates, and quadrants of the Reynolds stresses. Part of this work was funded by Airbus Group. Simulations were performed on the ARCHER Supercomputer (UKTC Grant).

Assessment of Hemodynamic Conditions in the Aorta Following Root Replacement with Composite Valve-Conduit Graft.

PubMed

Cheng, Zhuo; Kidher, Emaddin; Jarral, Omar A; O'Regan, Declan P; Wood, Nigel B; Athanasiou, Thanos; Xu, Xiao Yun

2016-05-01

This paper presents the analysis of detailed hemodynamics in the aortas of four patients following replacement with a composite bio-prosthetic valve-conduit. Magnetic resonance image-based computational models were set up for each patient with boundary conditions comprising subject-specific three-dimensional inflow velocity profiles at the aortic root and central pressure waveform at the model outlet. Two normal subjects were also included for comparison. The purpose of the study was to investigate the effects of the valve-conduit on flow in the proximal and distal aorta. The results suggested that following the composite valve-conduit implantation, the vortical flow structure and hemodynamic parameters in the aorta were altered, with slightly reduced helical flow index, elevated wall shear stress and higher non-uniformity in wall shear compared to normal aortas. Inter-individual analysis revealed different hemodynamic conditions among the patients depending on the conduit configuration in the ascending aorta, which is a key factor in determining post-operative aortic flow. Introducing a natural curvature in the conduit to create a smooth transition between the conduit and native aorta may help prevent the occurrence of retrograde and recirculating flow in the aortic arch, which is particularly important when a large portion or the entire ascending aorta needs to be replaced.

Large-scale structures in turbulent Couette flow

NASA Astrophysics Data System (ADS)

Kim, Jung Hoon; Lee, Jae Hwa

2016-11-01

Direct numerical simulation of fully developed turbulent Couette flow is performed with a large computational domain in the streamwise and spanwise directions (40 πh and 6 πh) to investigate streamwise-scale growth mechanism of the streamwise velocity fluctuating structures in the core region, where h is the channel half height. It is shown that long streamwise-scale structures (> 3 h) are highly energetic and they contribute to more than 80% of the turbulent kinetic energy and Reynolds shear stress, compared to previous studies in canonical Poiseuille flows. Instantaneous and statistical analysis show that negative-u' structures on the bottom wall in the Couette flow continuously grow in the streamwise direction due to mean shear, and they penetrate to the opposite moving wall. The geometric center of the log layer is observed in the centerline with a dominant outer peak in streamwise spectrum, and the maximum streamwise extent for structure is found in the centerline, similar to previous observation in turbulent Poiseuille flows at high Reynolds number. Further inspection of time-evolving instantaneous fields clearly exhibits that adjacent long structures combine to form a longer structure in the centerline. This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (NRF-2014R1A1A2057031).

Effect of wall pattern configurations on Stokes flow through a microchannel with superhydrophobic slip

NASA Astrophysics Data System (ADS)

Mak, H. M.; Ng, C. O.

2010-11-01

The present work aims to study low-Reynolds-number flow through a microchannel with superhydrophobic surfaces, which contain a periodic array of parallel ribs on the upper and lower walls. Mimicking impregnation, the liquid is allowed to penetrate the grooves between the ribs which are filled with an inviscid gas. The array of ribs and grooves gives a heterogeneous wall boundary condition to the channel flow, with partial-slip boundary condition on the solid surface and no-shear boundary condition on the liquid-gas interface. Using the method of eigenfunction expansions and domain decomposition, semi-analytical models are developed for four configurations. Two of them are for longitudinal flow and the others are for transverse flow. For each flow orientation, in-phase and out-phase alignments of ribs between the upper and lower walls are analyzed. The effect of the phase alignments of ribs is appreciable when the channel height is sufficiently small. In-phase alignment gives rise to a larger effective slip length in longitudinal flow. On the contrary, out-phase alignment will yield a larger effective slip length in transverse flow. This work was supported by the Research Grants Council of the Hong Kong Special Administrative Region, China, through Project HKU 7156/09E.

The Effect of Spatial and Temporal Resolution of Cine Phase Contrast MRI on Wall Shear Stress and Oscillatory Shear Index Assessment

PubMed Central

Gijsen, Frank J.; Marquering, Henk; van Ooij, Pim; vanBavel, Ed; Wentzel, Jolanda J.; Nederveen, Aart J.

2016-01-01

Introduction Wall shear stress (WSS) and oscillatory shear index (OSI) are associated with atherosclerotic disease. Both parameters are derived from blood velocities, which can be measured with phase-contrast MRI (PC-MRI). Limitations in spatiotemporal resolution of PC-MRI are known to affect these measurements. Our aim was to investigate the effect of spatiotemporal resolution using a carotid artery phantom. Methods A carotid artery phantom was connected to a flow set-up supplying pulsatile flow. MRI measurement planes were placed at the common carotid artery (CCA) and internal carotid artery (ICA). Two-dimensional PC-MRI measurements were performed with thirty different spatiotemporal resolution settings. The MRI flow measurement was validated with ultrasound probe measurements. Mean flow, peak flow, flow waveform, WSS and OSI were compared for these spatiotemporal resolutions using regression analysis. The slopes of the regression lines were reported in %/mm and %/100ms. The distribution of low and high WSS and OSI was compared between different spatiotemporal resolutions. Results The mean PC-MRI CCA flow (2.5±0.2mL/s) agreed with the ultrasound probe measurements (2.7±0.02mL/s). Mean flow (mL/s) depended only on spatial resolution (CCA:-13%/mm, ICA:-49%/mm). Peak flow (mL/s) depended on both spatial (CCA:-13%/mm, ICA:-17%/mm) and temporal resolution (CCA:-19%/100ms, ICA:-24%/100ms). Mean WSS (Pa) was in inverse relationship only with spatial resolution (CCA:-19%/mm, ICA:-33%/mm). OSI was dependent on spatial resolution for CCA (-26%/mm) and temporal resolution for ICA (-16%/100ms). The regions of low and high WSS and OSI matched for most of the spatiotemporal resolutions (CCA:30/30, ICA:28/30 cases for WSS; CCA:23/30, ICA:29/30 cases for OSI). Conclusion We show that both mean flow and mean WSS are independent of temporal resolution. Peak flow and OSI are dependent on both spatial and temporal resolution. However, the magnitude of mean and peak flow, WSS and OSI, and the spatial distribution of OSI and WSS did not exhibit a strong dependency on spatiotemporal resolution. PMID:27669568

Influence of Brownian motion on blood platelet flow behavior and adhesive dynamics near a planar wall.

PubMed

Mody, Nipa A; King, Michael R

2007-05-22

We used the platelet adhesive dynamics computational method to study the influence of Brownian motion of a platelet on its flow characteristics near a surface in the creeping flow regime. Two important characterizations were done in this regard: (1) quantification of the platelet's ability to contact the surface by virtue of the Brownian forces and torques acting on it, and (2) determination of the relative importance of Brownian motion in promoting surface encounters in the presence of shear flow. We determined the Peclet number for a platelet undergoing Brownian motion in shear flow, which could be expressed as a simple linear function of height of the platelet centroid, H from the surface Pe (platelet) = . (1.56H + 0.66) for H > 0.3 microm. Our results demonstrate that at timescales relevant to shear flow in blood Brownian motion plays an insignificant role in influencing platelet motion or creating further opportunities for platelet-surface contact. The platelet Peclet number at shear rates >100 s-1 is large enough (>200) to neglect platelet Brownian motion in computational modeling of flow in arteries and arterioles for most practical purposes even at very close distances from the surface. We also conducted adhesive dynamics simulations to determine the effects of platelet Brownian motion on GPIbalpha-vWF-A1 single-bond dissociation dynamics. Brownian motion was found to have little effect on bond lifetime and caused minimal bond stressing as bond rupture forces were calculated to be less than 0.005 pN. We conclude from our results that, for the case of platelet-shaped cells, Brownian motion is not expected to play an important role in influencing flow characteristics, platelet-surface contact frequency, and dissociative binding phenomena under flow at physiological shear rates (>50 s(-1)).

Post-failure characteristics of weathered soils in Korea: determination of rheological thresholds and debris flow mobility

NASA Astrophysics Data System (ADS)

Jeong, Sueng-Won; Fukuoka, Hiroshi; Im, Sang-June

2013-04-01

Landslides in Korea are mainly triggered by localized summer heavy rainfall. The water infiltration, wetting and fluidization process are the key roles in slope instability. Mechanically, a loss in soil strength of the soil at weakend layer takes place as a result of water infiltration. The transition from slides to flows can be defined by the variation in strength parameters. In the flowing stage with large volume of sediments, debris flow impact may be governed by the rheology of the failed mass. We performed the rheological tests using the ball-measuring and vane-inserted rheometer and examined a possible threshold of landslides on mudstone, weathered granitic and gneissic soils in the mountainous region of Korea. The materials examined exhibited the shear-thinning behavior, which is the viscosity decreases with increasing shear rates. There are positive relationships between liquidity index and rheological values (i.e., yield stress and viscosities). However, the difference in rheological properties is of significance for given shear rates. The effect of wall-slip in different geometries is emphasized. This work is also concerned with post-failure characteristics of rainfall-induced landslides that occur in Chuncheon, Miryang and Seoul debris flow occurrence in 2011. They are mainly composed of gneissic, sedimentary and gneissic weathered soils. The rheological properties is helpful to predict the mobilization of fine-laden debris flows. In the relationship between shear stress and shear rate, one of simplest rheological models, i.e., the ideal Bingham fluid model, is selected to examine the flow pattern and depositional features of debris flows. A comparison will be made for the debris flow occurence on weahtered soils in Korea.

A viscoelastic fluid-structure interaction model for carotid arteries under pulsatile flow.

PubMed

Wang, Zhongjie; Wood, Nigel B; Xu, Xiao Yun

2015-05-01

In this study, a fluid-structure interaction model (FSI) incorporating viscoelastic wall behaviour is developed and applied to an idealized model of the carotid artery under pulsatile flow. The shear and bulk moduli of the arterial wall are described by Prony series, where the parameters can be derived from in vivo measurements. The aim is to develop a fully coupled FSI model that can be applied to realistic arterial geometries with normal or pathological viscoelastic wall behaviour. Comparisons between the numerical and analytical solutions for wall displacements demonstrate that the coupled model is capable of predicting the viscoelastic behaviour of carotid arteries. Comparisons are also made between the solid only and FSI viscoelastic models, and the results suggest that the difference in radial displacement between the two models is negligible. Copyright © 2015 John Wiley & Sons, Ltd.

Experimental study of the flow in the wake of a stationary sphere immersed in a turbulent boundary layer

NASA Astrophysics Data System (ADS)

van Hout, René; Eisma, Jerke; Elsinga, Gerrit E.; Westerweel, Jerry

2018-02-01

In many applications, finite-sized particles are immersed in a turbulent boundary layer (TBL) and it is of interest to study wall effects on the instantaneous shedding of turbulence structures and associated mean velocity and Reynolds stress distributions. Here, 3D flow field dynamics in the wake of a prototypical, small sphere (D+=50 , 692

Wall shear stress effects of different endodontic irrigation techniques and systems.

PubMed

Goode, Narisa; Khan, Sara; Eid, Ashraf A; Niu, Li-na; Gosier, Johnny; Susin, Lisiane F; Pashley, David H; Tay, Franklin R

2013-07-01

This study examined débridement efficacy as a result of wall shear stresses created by different irrigant delivery/agitation techniques in an inaccessible recess of a curved root canal model. A reusable, curved canal cavity containing a simulated canal fin was milled into mirrored titanium blocks. Calcium hydroxide (Ca(OH)2) paste was used as debris and loaded into the canal fin. The titanium blocks were bolted together to provide a fluid-tight seal. Sodium hypochlorite was delivered at a previously-determined flow rate of 1 mL/min that produced either negligible or no irrigant extrusion pressure into the periapex for all the techniques examined. Nine irrigation delivery/agitation techniques were examined: NaviTip passive irrigation control, Max-i-Probe(®) side-vented needle passive irrigation, manual dynamic agitation (MDA) using non-fitting and well-fitting gutta-percha points, EndoActivator™ sonic agitation with medium and large points, VPro™ EndoSafe™ irrigation system, VPro™ StreamClean™ continuous ultrasonic irrigation and EndoVac apical negative pressure irrigation. Débridement efficacies were analysed with Kruskal-Wallis ANOVA and Dunn's multiple comparisons tests (α=0.05). EndoVac was the only technique that removed more than 99% calcium hydroxide debris from the canal fin at the predefined flow rate. This group was significantly different (p<0.05) from the other groups that exhibited incomplete Ca(OH)2 removal. The ability of the EndoVac system to significantly clean more debris from a mechanically inaccessible recess of the model curved root canal may be caused by robust bubble formation during irrigant delivery, creating higher wall shear stresses by a two-phase air-liquid flow phenomenon that is well known in other industrial débridement systems. Copyright © 2013 Elsevier Ltd. All rights reserved.

An Experimental Study of a Separated/Reattached Flow Behind a Backward-Facing Step. Re(sub h) = 37,000

NASA Technical Reports Server (NTRS)

Jovic, Srba

1996-01-01

An experimental study was carried out to investigate turbulent structure of a two-dimensional incompressible separating/reattaching boundary layer behind a backward-facing step. Hot-wire measurement technique was used to measure three Reynolds stresses and higher-order mean products of velocity fluctuations. The Reynolds number, Re(sub h), based on the step height, h, and the reference velocity, U(sub 0), was 37,000. The upstream oncoming flow was fully developed turbulent boundary layer with the Re(sub theta) = 3600. All turbulent properties, such as Reynolds stresses, increase dramatically downstream of the step within an internally developing mixing layer. Distributions of dimensionless mean velocity, turbulent quantities and antisymmetric distribution of triple velocity products in the separated free shear layer suggest that the shear layer above the recirculating region strongly resembles free-shear mixing layer structure. In the reattachment region close to the wall, turbulent diffusion term balances the rate of dissipation since advection and production terms appear to be negligibly small. Further downstream, production and dissipation begin to dominate other transport processes near the wall indicating the growth of an internal turbulent boundary layer. In the outer region, however, the flow still has a memory of the upstream disturbance even at the last measuring station of 51 step-heights. The data show that the structure of the inner layer recovers at a much faster rate than the outer layer structure. The inner layer structure resembles the near-wall structure of a plane zero pressure-gradient turbulent boundary layer (plane TBL) by 25h to 30h, while the outer layer structure takes presumably over 100h.

Numerical Technique for Analyzing Rotating Rake Mode Measurements in a Duct With Passive Treatment and Shear Flow

NASA Technical Reports Server (NTRS)

Dahl, Milo D.; Sutliff, Daniel L.

2007-01-01

A technique is presented for the analysis of measured data obtained from a rotating microphone rake system. The system is designed to measure the interaction modes of ducted fans. A Fourier analysis of the data from the rotating system results in a set of circumferential mode levels at each radial location of a microphone inside the duct. Radial basis functions are then least-squares fit to this data to obtain the radial mode amplitudes. For ducts with soft walls and mean flow, the radial basis functions must be numerically computed. The linear companion matrix method is used to obtain both the eigenvalues of interest, without an initial guess, and the radial basis functions. The governing equations allow for the mean flow to have a boundary layer at the wall. In addition, a nonlinear least-squares method is used to adjust the wall impedance to best fit the data in an attempt to use the rotating system as an in-duct wall impedance measurement tool. Simulated and measured data are used to show the effects of wall impedance and mean flow on the computed results.

Variable-viscosity thermal hemodynamic slip flow conveying nanoparticles through a permeable-walled composite stenosed artery

NASA Astrophysics Data System (ADS)

Akbar, Noreen Sher; Tripathi, Dharmendra; Bég, O. Anwar

2017-07-01

This paper presents a mathematical model for simulating viscous, incompressible, steady-state blood flow containing copper nanoparticles and coupled heat transfer through a composite stenosed artery with permeable walls. Wall slip hydrodynamic and also thermal buoyancy effects are included. The artery is simulated as an isotropic elastic tube, following Joshi et al. (2009), and a variable viscosity formulation is employed for the flowing blood. The equations governing the transport phenomena are non-dimensionalized and the resulting boundary value problem is solved analytically in the steady state subject to physically appropriate boundary conditions. Numerical computations are conducted to quantify the effects of relevant hemodynamic, thermophysical and nanoscale parameters emerging in the model on velocity and temperature profiles, wall shear stress, impedance resistance and also streamline distributions. The model may be applicable to drug fate transport modeling with nanoparticle agents and also to the optimized design of nanoscale medical devices for diagnosing stenotic diseases in circulatory systems.

Direct numerical simulation of turbulent channel flow with spanwise alternatively distributed strips control

NASA Astrophysics Data System (ADS)

Ni, Weidan; Lu, Lipeng; Fang, Jian; Moulinec, Charles; Yao, Yufeng

2018-05-01

The effect of spanwise alternatively distributed strips (SADS) control on turbulent flow in a plane channel has been studied by direct numerical simulations to investigate the characteristics of large-scale streamwise vortices (LSSVs) induced by small-scale active wall actuation, and their potential in suppressing flow separation. SADS control is realized by alternatively arranging out-of-phase control (OPC) and in-phase control (IPC) wall actuations on the lower channel wall surface, in the spanwise direction. It is found that the coherent structures are suppressed or enhanced alternatively by OPC or IPC, respectively, leading to the formation of a vertical shear layer, which is responsible for the LSSVs’ presence. Large-scale low-speed region can also be observed above the OPC strips, which resemble large-scale low-speed streaks. LSSVs are found to be in a statistically-converged steady state and their cores are located between two neighboring OPC and IPC strips. Their motions contribute significantly to the momentum transport in the wall-normal and spanwise directions, demonstrating their potential ability to suppress flow separation.

A Wall-Distance-Free k-ω SST Turbulence Model

NASA Astrophysics Data System (ADS)

Gleize, Vincent; Burnley, Victor

2001-11-01

In the calculation of flows around aircraft and aerodynamic bodies, the Shear-Stress Transport (SST) model by Menter has been used extensively due to its good prediction of flows with adverse pressure gradients. One main drawback of this model is the need to calculate the distance from the wall. While this is not a serious drawback for steady state calculations on non-moving grids, this calculation can become very cumbersome and expensive for unsteady simulations, especially when using unstructured grids. In this case, the wall-distance needs to be determined after each iteration. To avoid this problem, a new model is proposed which provides the benefits of the SST correction and avoids the freestream dependency of the solution, while not requiring the wall-distance. The first results for a wide range of test cases show that this model produces very good agreement with experimental data for flows with adverse pressure gradients, separation zones and shock-boundary layer interactions, closely matching the results obtained with the original SST model. This model should be very useful for unsteady calculations, such as store separation, grid adaptation, and other practical flows.

Augmentative effect of pulsatility on the wall shear stress in tube flow.

PubMed

Nakata, M; Tatsumi, E; Tsukiya, T; Taenaka, Y; Nishimura, T; Nishinaka, T; Takano, H; Masuzawa, T; Ohba, K

1999-08-01

Wall shear stress (WSS) has been considered to play an important role in the physiological and metabolic functions of the vascular endothelial cells. We investigated the effects of the pulse rate and the maximum flow rate on the WSS to clarify the influence of pulsatility. Water was perfused in a 1/2 inch transparent straight cylinder with a nonpulsatile centrifugal pump and a pulsatile pneumatic ventricular assist device (VAD). In nonpulsatile flow (NF), the flow rate was changed 1 to 6 L/min by 1 L/min increments to obtain standard values of WSS at each flow rate. In pulsatile flow (PF), the pulse rate was controlled at 40, 60, and 80 bpm, and the maximum flow rate was varied from 3.3 to 12.0 L/min while the mean flow rate was kept at 3 L/min. The WSS was estimated from the velocity profile at measuring points using the laser illuminated fluorescence method. In NF, the WSS was 12.0 dyne/cm2 at 3 L/min and 33.0 dyne/cm2 at 6 L/min. In PF, the pulse rate change with the same mean, and the maximum flow rate did not affect WSS. On the other hand, the increase in the maximum flow rate at the constant mean flow rate of 3 L/min augmented the mean WSS from 13.1 to 32.9 dyne/cm2. We concluded that the maximum flow rate exerted a substantial augmentative effect on WSS, and the maximum flow rate was a dominant factor of pulsatility in this effect.

Acoustic energy exchange through flow turning

NASA Astrophysics Data System (ADS)

Baum, Joseph D.

1987-01-01

A numerical investigation of the mechanisms of acoustic energy exchange between the mean and acoustic flow fields in resonance chambers, such as rocket engines, is reported. A noniterative linearized block implicit scheme was used to solve the time-dependent compressible Navier-Stokes equations. Two test cases were investigated: acoustic wave propagation in a tube with a coexisting sheared mean flow (the refraction test) and acoustic wave propagation in a tube where the mean sheared flow was injected into the tube through its lateral boundary (the flow turning study). For flow turning, significant excitation of mean flow energy was observed at two locations: at the edge of the acoustic boundary layer and within a zone adjacent to the acoustic boundary layer extending up to 0.1 radii away from the wall. A weaker streaming effect was observed for the refraction study, and only at the edge of the acoustic boundary layer. The total dissipation for the flow turning test was twice the dissipation for refraction.

Longitudinal pressure-driven flows between superhydrophobic grooved surfaces: Large effective slip in the narrow-channel limit

NASA Astrophysics Data System (ADS)

Schnitzer, Ory; Yariv, Ehud

2017-07-01

The gross amplification of the fluid velocity in pressure-driven flows due to the introduction of superhydrophobic walls is commonly quantified by an effective slip length. The canonical duct-flow geometry involves a periodic structure of longitudinal shear-free stripes at either one or both of the bounding walls, corresponding to flat-meniscus gas bubbles trapped within a periodic array of grooves. This grating configuration is characterized by two geometric parameters, namely the ratio κ of channel width to microstructure period and the areal fraction Δ of the shear-free stripes. For wide channels, κ ≫1 , this geometry is known to possess an approximate solution where the dimensionless slip length λ , normalized by the duct semiwidth, is small, indicating a weak superhydrophobic effect. We here address the other extreme of narrow channels, κ ≪1 , identifying large O (κ-2) values of λ for the symmetric configuration, where both bounding walls are superhydrophobic. This velocity enhancement is associated with an unconventional Poiseuille-like flow profile where the parabolic velocity variation takes place in a direction parallel (rather than perpendicular) to the boundaries. Use of matched asymptotic expansions and conformal-mapping techniques provides λ up to O (κ-1) , establishing the approximationλ ˜κ-2Δ/33 +κ-1Δ/2π ln4 +⋯, which is in excellent agreement with a semianalytic solution of the dual equations governing the respective coefficients of a Fourier-series representation of the fluid velocity. No similar singularity occurs in the corresponding asymmetric configuration, involving a single superhydrophobic wall; in that geometry, a Hele-Shaw approximation shows that λ =O (1 ) .

In-situ shear stress indicator using heated strain gages at the flow boundary

NASA Astrophysics Data System (ADS)

Yeh, Chi-An; Yang, Fuling

2011-11-01

This work borrows the concept of hot-wire anemometry and sketch a technique that uses local heat transfer to infer the flow field and the corresponding stress. Conventional strain gages were mounted at the flow solid boundary as the heat source and acrylic boundary was chosen for its low thermal conductivity ensuring heat accumulation when a gage is energized. The gage would now work in slightly overheated state and its self-heating leads to an additional thermal strain. When exposed to a flow field, heat is brought away by local forced convection, resulting in deviations in gage signal from that developed in quiescent liquid. We have developed a facility to achieve synchronous gage measurements at different locations on a solid boundary. Three steady flow motions were considered: circular Couette flow, rectilinear uniform flow, and rectilinear oscillating flow. Preliminary tests show the gage reading does respond to the imposed flow through thermal effects and greater deviation was measured in flows of higher shear strain rates. The correlation between the gage signals and the imposed flow field is further examined by theoretical analysis. We also introduced a second solid boundary to the vicinity of the gage in the two rectilinear flows. The gage readings demonstrate rises in its magnitudes indicating wall amplification effect on the local shear strain, agreeing to the drag augmentation by a second solid boundary reported in many multiphase flow literatures.

Numerical analysis of the effect of turbulence transition on the hemodynamic parameters in human coronary arteries

PubMed Central

Gawandalkar, Udhav Ulhas; Kini, Girish; Buradi, Abdulrajak; Araki, Tadashi; Ikeda, Nobutaka; Nicolaides, Andrew; Laird, John R.; Saba, Luca; Suri, Jasjit S.

2016-01-01

Background Local hemodynamics plays an important role in atherogenesis and the progression of coronary atherosclerosis disease (CAD). The primary biological effect due to blood turbulence is the change in wall shear stress (WSS) on the endothelial cell membrane, while the local oscillatory nature of the blood flow affects the physiological changes in the coronary artery. In coronary arteries, the blood flow Reynolds number ranges from few tens to several hundreds and hence it is generally assumed to be laminar while calculating the WSS calculations. However, the pulsatile blood flow through coronary arteries under stenotic condition could result in transition from laminar to turbulent flow condition. Methods In the present work, the onset of turbulent transition during pulsatile flow through coronary arteries for varying degree of stenosis (i.e., 0%, 30%, 50% and 70%) is quantitatively analyzed by calculating the turbulent parameters distal to the stenosis. Also, the effect of turbulence transition on hemodynamic parameters such as WSS and oscillatory shear index (OSI) for varying degree of stenosis is quantified. The validated transitional shear stress transport (SST) k-ω model used in the present investigation is the best suited Reynolds averaged Navier-Stokes turbulence model to capture the turbulent transition. The arterial wall is assumed to be rigid and the dynamic curvature effect due to myocardial contraction on the blood flow has been neglected. Results Our observations shows that for stenosis 50% and above, the WSSavg, WSSmax and OSI calculated using turbulence model deviates from laminar by more than 10% and the flow disturbances seems to significantly increase only after 70% stenosis. Our model shows reliability and completely validated. Conclusions Blood flow through stenosed coronary arteries seems to be turbulent in nature for area stenosis above 70% and the transition to turbulent flow begins from 50% stenosis. PMID:27280084

Hydrostatic pressure and shear stress affect endothelin-1 and nitric oxide release by endothelial cells in bioreactors.

PubMed

Vozzi, Federico; Bianchi, Francesca; Ahluwalia, Arti; Domenici, Claudio

2014-01-01

Abundant experimental evidence demonstrates that endothelial cells are sensitive to flow; however, the effect of fluid pressure or pressure gradients that are used to drive viscous flow is not well understood. There are two principal physical forces exerted on the blood vessel wall by the passage of intra-luminal blood: pressure and shear. To analyze the effects of pressure and shear independently, these two stresses were applied to cultured cells in two different types of bioreactors: a pressure-controlled bioreactor and a laminar flow bioreactor, in which controlled levels of pressure or shear stress, respectively, can be generated. Using these bioreactor systems, endothelin-1 (ET-1) and nitric oxide (NO) release from human umbilical vein endothelial cells were measured under various shear stress and pressure conditions. Compared to the controls, a decrease of ET-1 production by the cells cultured in both bioreactors was observed, whereas NO synthesis was up-regulated in cells under shear stress, but was not modulated by hydrostatic pressure. These results show that the two hemodynamic forces acting on blood vessels affect endothelial cell function in different ways, and that both should be considered when planning in vitro experiments in the presence of flow. Understanding the individual and synergic effects of the two forces could provide important insights into physiological and pathological processes involved in vascular remodeling and adaptation. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Viscous versus inviscid exact coherent states in high Reynolds number wall flows

NASA Astrophysics Data System (ADS)

Montemuro, Brandon; Klewicki, Joe; White, Chris; Chini, Greg

2017-11-01

Streamwise-averaged motions consisting of streamwise-oriented streaks and vortices are key components of exact coherent states (ECS) arising in incompressible wall-bounded shear flows. These invariant solutions are believed to provide a scaffold in phase space for the turbulent dynamics realized at large Reynolds number Re . Nevertheless, many ECS, including upper-branch states, have a large- Re asymptotic structure in which the effective Reynolds number governing the streak and roll dynamics is order unity. Although these viscous ECS very likely play a role in the dynamics of the near-wall region, they cannot be relevant to the inertial layer, where the leading-order mean dynamics are known to be inviscid. In particular, viscous ECS cannot account for the observed regions of quasi-uniform streamwise momentum and interlaced internal shear layers (or `vortical fissures') within the inertial layer. In this work, a large- Re asymptotic analysis is performed to extend the existing self-sustaining-process/vortex-wave-interaction theory to account for largely inviscid ECS. The analysis highlights feedback mechanisms between the fissures and uniform momentum zones that can enable their self-sustenance at extreme Reynolds number. NSF CBET Award 1437851.

Heat transfer enhancement in free convection flow of CNTs Maxwell nanofluids with four different types of molecular liquids.

PubMed

Aman, Sidra; Khan, Ilyas; Ismail, Zulkhibri; Salleh, Mohd Zuki; Al-Mdallal, Qasem M

2017-05-26

This article investigates heat transfer enhancement in free convection flow of Maxwell nanofluids with carbon nanotubes (CNTs) over a vertically static plate with constant wall temperature. Two kinds of CNTs i.e. single walls carbon nanotubes (SWCNTs) and multiple walls carbon nanotubes (MWCNTs) are suspended in four different types of base liquids (Kerosene oil, Engine oil, water and ethylene glycol). Kerosene oil-based nanofluids are given a special consideration due to their higher thermal conductivities, unique properties and applications. The problem is modelled in terms of PDE's with initial and boundary conditions. Some relevant non-dimensional variables are inserted in order to transmute the governing problem into dimensionless form. The resulting problem is solved via Laplace transform technique and exact solutions for velocity, shear stress and temperature are acquired. These solutions are significantly controlled by the variations of parameters including the relaxation time, Prandtl number, Grashof number and nanoparticles volume fraction. Velocity and temperature increases with elevation in Grashof number while Shear stress minimizes with increasing Maxwell parameter. A comparison between SWCNTs and MWCNTs in each case is made. Moreover, a graph showing the comparison amongst four different types of nanofluids for both CNTs is also plotted.

Visualization of three pathways for macromolecule transport across cultured endothelium and their modification by flow.

PubMed

Ghim, Mean; Alpresa, Paola; Yang, Sung-Wook; Braakman, Sietse T; Gray, Stephen G; Sherwin, Spencer J; van Reeuwijk, Maarten; Weinberg, Peter D

2017-11-01

Transport of macromolecules across vascular endothelium and its modification by fluid mechanical forces are important for normal tissue function and in the development of atherosclerosis. However, the routes by which macromolecules cross endothelium, the hemodynamic stresses that maintain endothelial physiology or trigger disease, and the dependence of transendothelial transport on hemodynamic stresses are controversial. We visualized pathways for macromolecule transport and determined the effect on these pathways of different types of flow. Endothelial monolayers were cultured under static conditions or on an orbital shaker producing different flow profiles in different parts of the wells. Fluorescent tracers that bound to the substrate after crossing the endothelium were used to identify transport pathways. Maps of tracer distribution were compared with numerical simulations of flow to determine effects of different shear stress metrics on permeability. Albumin-sized tracers dominantly crossed the cultured endothelium via junctions between neighboring cells, high-density lipoprotein-sized tracers crossed at tricellular junctions, and low-density lipoprotein-sized tracers crossed through cells. Cells aligned close to the angle that minimized shear stresses across their long axis. The rate of paracellular transport under flow correlated with the magnitude of these minimized transverse stresses, whereas transport across cells was uniformly reduced by all types of flow. These results contradict the long-standing two-pore theory of solute transport across microvessel walls and the consensus view that endothelial cells align with the mean shear vector. They suggest that endothelial cells minimize transverse shear, supporting its postulated proatherogenic role. Preliminary data show that similar tracer techniques are practicable in vivo. NEW & NOTEWORTHY Solutes of increasing size crossed cultured endothelium through intercellular junctions, through tricellular junctions, or transcellularly. Cells aligned to minimize the shear stress acting across their long axis. Paracellular transport correlated with the level of this minimized shear, but transcellular transport was reduced uniformly by flow regardless of the shear profile. Copyright © 2017 the American Physiological Society.

Hydrothermal quartz formation during fluctuations of brittle shear-zone activity and fluid flow: grain growth and deformation structures of the Pfahl shear zone (Germany)

NASA Astrophysics Data System (ADS)

Yilmaz, T.; Prosser, G.; Liotta, D.; Kruhl, J. H.

2012-12-01

The Bavarian Pfahl shear zone is a WNW-ESE trending dextral strike-slip shear zone at the SW margin of the Bohemian Massif (Central Europe). It was discontinuously active during decreasing PT-conditions, i.e. from ductile to brittle, from the late-Carboniferous to the late-Cretaceous - Paleocene times. Triassic hydrothermal activity produced a 150 km long and 30-100 m wide quartz dyke along the main fault, surrounded by sheared basement rocks. Within a zone of >10 m metasomatism transformed the wall rocks to mostly kaolinite, chlorite and phyllosilicates. The quartz dyke exhibits a layered to lenticular and partly symmetric structure with different types of quartz masses, transected by a complex quartz vein network. This already indicates pulses of fluid flux and fragmentation during the lifetime of the shear zone. Analyses by optical microscopy, cathodoluminescence (CL) and SEM-EDX reveal at least four subsequent stages of quartz crystallization and fragmentation. (i) The oldest generation of quartz is represented by a homogeneous dark grey to reddish quartz mass made up by ~10-20 μm-sized crystals. It contains mm- to cm-sized angular wall-rock fragments, completely altered to kaolinite, indicating intense wall-rock alteration prior to the earliest event of silica precipitation. This rules out the possibility that the quartz mass developed from silicification of the wall rocks. This first type of quartz occurs as cm- to dm-large angular fragments in (ii) a light grey to pink quartz mass formed by ~10-50 μm-sized crystals. The different colours result from variable types and amounts of inclusions. Quartz of both generations shows random crystallographic orientations and complex inclusion structures. It probably developed during two fragmentation events and possibly from a silica gel precursor that crystallized after precipitation. (iii) The third quartz generation formed as a set of mm- to dm-wide veins roughly parallel to the trend of the Pfahl zone, crosscutting the first generations of fine-grained quartz mass and the wall rocks, in connection to intense fracturing and brecciation. The complex geometry of the vein sets points to multiple fluid injections and brecciation, as additionally indicated by coarse quartz with different inclusion and CL intensity. Temporal changes of strain rate are indicated by crystal plastic deformation structures in quartz, which overprint brittle structures. (iv) The fourth quartz generation occurs in mm- to dm-thick quartz veins, partly open as geodes, filling N-S oriented cm- to dm-spaced fractures that crosscut the earlier quartz masses and veins and extend at least several meters into the wall rock. They indicate the last activity of the shear-zone in a constant kinematic framework. Summarizing, the Pfahl shear zone shows brittle-ductile deformation during the long-term activity of a large-scale hydrothermal system. Consequently, it represents an excellent example where different generations of quartz precipitation can be connected to fluctuations of fluid flow and strain rate.

Advancements in engineering turbulence modeling

NASA Technical Reports Server (NTRS)

Shih, T.-H.

1991-01-01

Some new developments in two-equation models and second order closure models are presented. Two-equation models (k-epsilon models) have been widely used in computational fluid dynamics (CFD) for engineering problems. Most of low-Reynolds number two-equation models contain some wall-distance damping functions to account for the effect of wall on turbulence. However, this often causes the confusion and difficulties in computing flows with complex geometry and also needs an ad hoc treatment near the separation and reattachment points. A set of modified two-equation models is proposed to remove the aforementioned shortcomings. The calculations using various two-equation models are compared with direct numerical simulations of channel flow and flat boundary layers. Development of a second order closure model is also discussed with emphasis on the modeling of pressure related correlation terms and dissipation rates in the second moment equations. All the existing models poorly predict the normal stresses near the wall and fail to predict the 3-D effect of mean flow on the turbulence (e.g. decrease in the shear stress caused by the cross flow in the boundary layer). The newly developed second order near-wall turbulence model is described and is capable of capturing the near-wall behavior of turbulence as well as the effect of 3-D mean flow on the turbulence.

Heat Transfer Through Turbulent Friction Layers

NASA Technical Reports Server (NTRS)

Reichardt, H.

1943-01-01

The "general Prandtl number" Pr(exp 1) - A(sub q)/A Pr, aside from the Reynolds number determines the ratio of turbulent to molecular heat transfer, and the temperature distribution in turbulent friction layers. A(sub q) = exchange coefficient for heat; A = exchange coefficient for momentum transfer. A formula is derived from the equation defining the general Prandtl number which describes the temperature as a function of the velocity. For fully developed thermal boundary layers all questions relating to heat transfer to and from incompressible fluids can be treated in a simple manner if the ratio of the turbulent shear stress to the total stress T(sub t)/T in the layers near the wall is known, and if the A(sub q)/A can be regarded as independent of the distance from the wall. The velocity distribution across a flat smooth channel and deep into the laminar sublayer was measured for isothermal flow to establish the shear stress ratio T(sub t)/T and to extend the universal wall friction law. The values of T(sub t)/T which resulted from these measurements can be approximately represented by a linear function of the velocity in the laminar-turbulent transition zone. The effect of the temperature relationship of the material values on the flow near the wall is briefly analyzed. It was found that the velocity at the laminar boundary (in contrast to the thickness of the laminar layer) is approximately independent of the temperature distribution. The temperature gradient at the wall and the distribution of temperature and heat flow in the turbulent friction layers were calculated on the basis of the data under two equations. The derived formulas and the figures reveal the effects of the Prandtl number, the Reynolds number, the exchange quantities and the temperature relationship of the material values.

Two-way FSI modelling of blood flow through CCA accounting on-line medical diagnostics in hypertension

NASA Astrophysics Data System (ADS)

Czechowicz, K.; Badur, J.; Narkiewicz, K.

2014-08-01

Flow parameters can induce pathological changes in the arteries. We propose a method to asses those parameters using a 3D computer model of the flow in the Common Carotid Artery. Input data was acquired using an automatic 2D ultrasound wall tracking system. This data has been used to generate a 3D geometry of the artery. The diameter and wall thickness have been assessed individually for every patient, but the artery has been taken as a 75mm straight tube. The Young's modulus for the arterial walls was calculated using the pulse pressure, diastolic (minimal) diameter and wall thickness (IMT). Blood flow was derived from the pressure waveform using a 2-parameter Windkessel model. The blood is assumed to be non-Newtonian. The computational models were generated and calculated using commercial code. The coupling method required the use of Arbitrary Lagrangian-Euler formulation to solve Navier-Stokes and Navier-Lame equations in a moving domain. The calculations showed that the distention of the walls in the model is not significantly different from the measurements. Results from the model have been used to locate additional risk factors, such as wall shear stress or circumferential stress, that may predict adverse hypertension complications.

Stratification of a two-phase monodisperse system in a plane laminar flow

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fedoseev, V. B., E-mail: vbfedoseev@yandex.ru

2016-05-15

A thermodynamic approach is used to describe the distribution of particles of a disperse phase in a plane laminar flow. The effect of the density, shape, and velocity of disperse particles in the flow is considered. Conditions are described under which various modes of stratification of the flow (near-wall, central, intermediate, and multilayer modes) arise. The equilibrium distributions obtained are self-similar; this allows one to compare the behavior of colloidal, highly disperse, coarsely disperse, and coarse-grain systems for various shear velocities and flow widths.

Direct detection and measurement of wall shear stress using a filamentous bio-nanoparticle

PubMed Central

Lobo, Daniela P.; Wemyss, Alan M.; Smith, David J.; Straube, Anne; Betteridge, Kai B.; Salmon, Andrew H. J.; Foster, Rebecca R.; Elhegni, Hesham E.; Satchell, Simon C.; Little, Haydn A.; Pacheco-Gómez, Raúl; Simmons, Mark J.; Hicks, Matthew R.; Bates, David O.; Dafforn, Timothy R.; Arkill, Kenton P.

2016-01-01

The wall shear stress (WSS) that a moving fluid exerts on a surface affects many processes including those relating to vascular function. WSS plays an important role in normal physiology (e.g. angiogenesis) and affects the microvasculature’s primary function of molecular transport. Points of fluctuating WSS show abnormalities in a number of diseases; however, there is no established technique for measuring WSS directly in physiological systems. All current methods rely on estimates obtained from measured velocity gradients in bulk flow data. In this work, we report a nanosensor that can directly measure WSS in microfluidic chambers with sub-micron spatial resolution by using a specific type of virus, the bacteriophage M13, which has been fluorescently labeled and anchored to a surface. It is demonstrated that the nanosensor can be calibrated and adapted for biological tissue, revealing WSS in micro-domains of cells that cannot be calculated accurately from bulk flow measurements. This method lends itself to a platform applicable to many applications in biology and microfluidics. PMID:27570611

Flow characteristics in the airways of a COPD patient with a saber-sheath trachea

NASA Astrophysics Data System (ADS)

Jin, Dohyun; Choi, Haecheon; Lee, Changhyun; Choi, Jiwoong; Kim, Kwanggi

2016-11-01

The chronic obstructive pulmonary disease (COPD) is a lung disease characterized by the irreversible airflow limitation caused by the damaged small airways and air sacs. Although COPD is not a disease of the trachea, many patients with COPD have saber-sheath tracheas. The effects of this morphological change in the trachea geometry on airflow are investigated in the present study. An unstructured finite volume method is used for the simulations during tidal breathing in normal and COPD airways, respectively. During inspiration, local large pressure drop is observed in the saber-sheath region of the COPD patient. During expiration, vortical structures are observed at the right main bronchus of the COPD airway, while the flow in the normal airway remains nearly laminar. High wall shear stress exists at convex regions of both airways during inspiration and expiration. However, due to the morphological changes in the COPD airway, relatively higher wall shear stress is observed in the patient airways.

Asymmetric bubble collapse and jetting in generalized Newtonian fluids

NASA Astrophysics Data System (ADS)

Shukla, Ratnesh K.; Freund, Jonathan B.

2017-11-01

The jetting dynamics of a gas bubble near a rigid wall in a non-Newtonian fluid are investigated using an axisymmetric simulation model. The bubble gas is assumed to be homogeneous, with density and pressure related through a polytropic equation of state. An Eulerian numerical description, based on a sharp interface capturing method for the shear-free bubble-liquid interface and an incompressible Navier-Stokes flow solver for generalized fluids, is developed specifically for this problem. Detailed simulations for a range of rheological parameters in the Carreau model show both the stabilizing and destabilizing non-Newtonian effects on the jet formation and impact. In general, for fixed driving pressure ratio, stand-off distance and reference zero-shear-rate viscosity, shear-thinning and shear-thickening promote and suppress jet formation and impact, respectively. For a sufficiently large high-shear-rate limit viscosity, the jet impact is completely suppressed. Thresholds are also determined for the Carreau power-index and material time constant. The dependence of these threshold rheological parameters on the non-dimensional driving pressure ratio and wall stand-off distance is similarly established. Implications for tissue injury in therapeutic ultrasound will be discussed.

Turbulent Flow Enhancement by Polyelectrolyte Additives: Mechanistic Implications for Drag Reduction.

NASA Astrophysics Data System (ADS)

Wagger, David Leonard

1992-01-01

The drag reduction phenomenon was experimentally studied in two pipes, of diameters 1.46 and 1.02 cm, using seven polyelectrolytic HPAM additives, with molecular weights from 1 to 20 times 10^6 g/mole and degree of backbone hydrolysis from 8 to 60%, at concentrations from 1 to 1000 wppm, in saline solutions containing from 0.3 to 0.00001 N NaCl. Both laminar and turbulent flow behavior were greatly influenced by salinity-induced changes in the initial conformation of the HPAM additives. Initially collapsed, random-coiling conformations exhibited Newtonian laminar flow and Type-A turbulent drag reduction, while initially extended conformations exhibited shear-thinning in laminar flow and Type-B turbulent drag reduction. The gross-flow physics of Type-B drag reduction were delineated. A characteristic "ladder" structure prevailed, with polymeric regime segments that were roughly parallel to, but shifted upward from, the Prandtl-Karman line. In the polymeric regime, both Type-A fan and Type -B ladder structures were essentially independent of pipe diameter, and were scaled by the wall shear stress. The wall shear stress also scaled degradation during drag reduction. New onset and slope increment correlations were presented for Type-A drag reduction by HPAM additives. In Type-B drag reduction, flow enhancement was found proportional to additive concentration, and the intrinsic slip, Sigma = S^'/(c/M _{rm w}), varied roughly as the third power of backbone chain links N_ {rm bb}. New intrinsic slip and retro-onset correlations were presented for Type-B drag reduction by HPAM additives. Analysis of Type-B literature revealed a wide range of additive efficacies, with specific slips S^'/c from 0.0001 to 4. For the most effective additives, HPAM and asbestos fibers, the additive-pervaded volume fraction per unit flow enhancement, X_{rm v} /S^' ~ 3000, implied that these additives align during drag reduction. The slip ratio R_{rm sc}, which is the relative flow enhancement induced in Type-A and Type-B drag reduction at constant additive concentration, was found to be a universal function of the normalized turbulent flow strength (Re_ {rm s}sqrtf/Re_ {rm s}sqrtf*). The extension of initially collapsed, random-coiling, HPAM macromolecules by the turbulent flow field thus seems independent of additive parameters and absolute wall shear stress levels. Gross flow additive equivalence was detected at iso-slip points, where different polymer solutions induced equal flow enhancements. At numerous such points, the collapsed to extended slip ratio at constant concentration, R_{rm sc}, was essentially equal to the extended to collapsed concentration ratio at constant slip, R _{rm cs}. Thus, for fixed total additive concentration, the R_{ rm sc} observed at any Re_ {rm s}sqrtf simply represents the fraction of originally collapsed macromolecules that have become extended in the flow, and thence effective in drag reduction. (Copies available exclusively from MIT Libraries, Rm. 14-0551, Cambridge, MA 02139-4307. Ph. 617 -253-5668; Fax 617-253-1690.).

Essential Development of Streamwise Vortical/Secondary Flows in All Ducts with Corners or Slope Discontinuities in Perimeter

NASA Astrophysics Data System (ADS)

Nagib, Hassan; Vidal, Alvaro; Vinuesa, Ricardo; Schlatter, Philipp

2017-11-01

Direct numerical simulations of fully-developed turbulent flow through various straight ducts with sharp or rounded corners of various radii were performed to study influence of corner geometry on secondary flows. Unexpectedly, increased rounding of corners in rectangular ducts does not lead to monotonic trend towards pipe case. Instead, secondary vortices relocate close to regions of wall-curvature change. This behavior is connected to inhomogeneous interaction between near-wall bursting events, which are further characterized in this work with definition of their local preferential direction, and vorticity fluxes. Although these motions are relatively weak compared to streamwise velocity their effect on turbulence statistics and shear-stress distribution is very important and has not been sufficiently documented or fully understood. Flow through spanwise-periodic channels, with sinusoidal function to define the geometry of wall, yw = +/- h + A cos(ωz) , was also studied as model flow that is parametrically changed using A and ω, while taking advantage of many resulting symmetries. Consequences on experimental facilities and comparisons between experiments and various numerical and theoretical models are discussed revealing the uniqueness of pipe flow.

Experimental study of shear rate dependence in perpetually sheared granular matter

NASA Astrophysics Data System (ADS)

Liu, Sophie Yang; Guillard, François; Marks, Benjy; Rognon, Pierre; Einav, Itai

2017-06-01

We study the shear behaviour of various granular materials by conducting novel perpetual simple shear experiments over four orders of magnitude of relatively low shear rates. The newly developed experimental apparatus employed is called "3D Stadium Shear Device" which is an extended version of the 2D Stadium Shear Device [1]. This device is able to provide a non-radial dependent perpetual shear flow and a nearly linear velocity profile between two oppositely moving shear walls. Using this device, we are able to test a large variety of granular materials. Here, we demonstrate the applicability of the device on glass beads (diameter 1 mm, 3 mm, and 14 mm) and rice. We particularly focus on studying these materials at very low inertial number I ranging from 10-6 to 10-2. We find that, within this range of I, the friction coefficient μ of glass beads has no shear rate dependence. A particularly appealing observation comes from testing rice, where the attainment of critical state develops under much longer duration than in other materials. Initially during shear we find a value of μ similar to that found for glass beads, but with time this value decreases gradually towards the asymptotic critical state value. The reason, we believe, lies in the fact that rice grains are strongly elongated; hence the time to achieve the stable μ is primarily controlled by the time for particles to align themselves with respect to the shear walls. Furthermore, the initial packing conditions of samples also plays a role in the evolution of μ when the shear strain is small, but that impact will eventually be erased after sufficient shear strain.

Modification of Turbulence Structures in a Channel Flow by Uniform Magnetic Fluxes

NASA Astrophysics Data System (ADS)

Lee, D.; Choi, H.; Kim, J.

1997-11-01

Effects of electromagnetic forcing on the near-wall turbulence are investigated by applying a uniform magnetic flux in a turbulent channel flow in the streamwise and spanwise directions, respectively. The base flow is a fully developed turbulent channel flow and the direct numerical simulation technique is used. The electromagnetic force induced from the magnetic fluxes reduces the intensity of the wall-layer structures and thus drag is significantly reduced. The wall-normal and spanwise velocity fluctuations and the Reynolds shear stress decrease with the increased magnetic flux in both directions. The streamwise velocity fluctuations increase with the streamwise magnetic flux, whereas they decrease with the spanwise magnetic flux. It is also shown that the spanwise magnetic flux is much more effective than the streamwise magnetic flux in reducing the skin-friction drag. Instantaneous Lorentz force vectors show that the flow motions by the near-wall vortices are directly inhibited by the spanwise magnetic flux, while they are less effectively inhibited by the streamwise magnetic flux. Other turbulence statistics that reveal the effects of the applied magnetic forcing will be presented. ^* Supported by KOSEF Contract No. 965-1008-003-2 and ONR Grant No. N00014-95-1-0352.

Development of a High-Order Navier-Stokes Solver Using Flux Reconstruction to Simulate Three-Dimensional Vortex Structures in a Curved Artery Model

NASA Astrophysics Data System (ADS)

Cox, Christopher

Low-order numerical methods are widespread in academic solvers and ubiquitous in industrial solvers due to their robustness and usability. High-order methods are less robust and more complicated to implement; however, they exhibit low numerical dissipation and have the potential to improve the accuracy of flow simulations at a lower computational cost when compared to low-order methods. This motivates our development of a high-order compact method using Huynh's flux reconstruction scheme for solving unsteady incompressible flow on unstructured grids. We use Chorin's classic artificial compressibility formulation with dual time stepping to solve unsteady flow problems. In 2D, an implicit non-linear lower-upper symmetric Gauss-Seidel scheme with backward Euler discretization is used to efficiently march the solution in pseudo time, while a second-order backward Euler discretization is used to march in physical time. We verify and validate implementation of the high-order method coupled with our implicit time stepping scheme using both steady and unsteady incompressible flow problems. The current implicit time stepping scheme is proven effective in satisfying the divergence-free constraint on the velocity field in the artificial compressibility formulation. The high-order solver is extended to 3D and parallelized using MPI. Due to its simplicity, time marching for 3D problems is done explicitly. The feasibility of using the current implicit time stepping scheme for large scale three-dimensional problems with high-order polynomial basis still remains to be seen. We directly use the aforementioned numerical solver to simulate pulsatile flow of a Newtonian blood-analog fluid through a rigid 180-degree curved artery model. One of the most physiologically relevant forces within the cardiovascular system is the wall shear stress. This force is important because atherosclerotic regions are strongly correlated with curvature and branching in the human vasculature, where the shear stress is both oscillatory and multidirectional. Also, the combined effect of curvature and pulsatility in cardiovascular flows produces unsteady vortices. The aim of this research as it relates to cardiovascular fluid dynamics is to predict the spatial and temporal evolution of vortical structures generated by secondary flows, as well as to assess the correlation between multiple vortex pairs and wall shear stress. We use a physiologically (pulsatile) relevant flow rate and generate results using both fully developed and uniform entrance conditions, the latter being motivated by the fact that flow upstream of a curved artery may not have sufficient straight entrance length to become fully developed. Under the two pulsatile inflow conditions, we characterize the morphology and evolution of various vortex pairs and their subsequent effect on relevant haemodynamic wall shear stress metrics.

Generalized wall function and its application to compressible turbulent boundary layer over a flat plate

NASA Astrophysics Data System (ADS)

Liu, J.; Wu, S. P.

2017-04-01

Wall function boundary conditions including the effects of compressibility and heat transfer are improved for compressible turbulent boundary flows. Generalized wall function formulation at zero-pressure gradient is proposed based on coupled velocity and temperature profiles in the entire near-wall region. The parameters in the generalized wall function are well revised. The proposed boundary conditions are integrated into Navier-Stokes computational fluid dynamics code that includes the shear stress transport turbulence model. Numerical results are presented for a compressible boundary layer over a flat plate at zero-pressure gradient. Compared with experimental data, the computational results show that the generalized wall function reduces the first grid spacing in the directed normal to the wall and proves the feasibility and effectivity of the generalized wall function method.

Prediction of Thrombus Growth: Effect of Stenosis and Reynolds Number.

PubMed

Hosseinzadegan, Hamid; Tafti, Danesh K

2017-06-01

Shear stresses play a major role in platelet-substrate interactions and thrombus formation and growth in blood flow, where under both pathological and physiological conditions platelet adhesion and accumulation occur. In this study, a shear-dependent continuum model for platelet activation, adhesion and aggregation is presented. The model was first verified under three different shear conditions and at two heparin levels. Three-dimensional simulations were then carried out to evaluate the performance of the model for severely damaged (stripped) aortas with mild and severe stenosis degrees in laminar flow regime. For these cases, linear shear-dependent functions were developed for platelet-surface and platelet-platelet adhesion rates. It was confirmed that the platelet adhesion rate is not only a function of Reynolds number (or wall shear rate) but also the stenosis severity of the vessel. General correlations for adhesion rates of platelets as functions of stenosis and Reynolds number were obtained based on these cases. Finally using the new platelet adhesion rates, the model was applied to different experimental systems and shown to agree well with measured platelet deposition.

Centrifugal Size-Separation Sieve for Granular Materials

NASA Technical Reports Server (NTRS)

Walton, Otis (Inventor); Dreyer, Christopher (Inventor); Riedel, Edward (Inventor)

2015-01-01

A centrifugal sieve and method utilizes centrifugal force in rapidly-rotated cylindrical or conical screens as the primary body force contributing to size segregation. Within the centrifugal acceleration field, vibration and/or shearing flows are induced to facilitate size segregation and eventual separation of the fines from the coarse material. Inside a rotating cylindrical or conical screen, a separately-rotated screw auger blade can be used to transport material along the rotating cylinder or conical wall and to induce shearing in the material.

Effect of guar gum and salt concentrations on drag reduction and shear degradation properties of turbulent flow of water in a pipe.

PubMed

Sokhal, Kamaljit Singh; Gangacharyulu, Dasaroju; Bulasara, Vijaya Kumar

2018-02-01

Concentrated solutions of guar gum in water (1000-3000ppm) with and without KCl salt (1000-4000ppm) were injected near the wall for a short period (2.5min) to investigate their effect on drag reduction in turbulent flow of water through a pipe (Re≈17000-45000). Relative to bulk solution, the concentrations of polymer and salt were 50-150ppm and 50-200ppm, respectively. A drag reduction of 71.45% was observed for 3000ppm of biopolymer without salt. Guar gum experienced mechanical degradation under high shear conditions and addition of KCl improved shear stability up to 47% (for Re≈45000). A polymer concentration of 3000ppm and salt concentration of 2000ppm in the injection fluid were found to be optimum for achieving the highest drag reduction with better shear stability. Results indicated that boundary layer injection shows better drag reduction ability than pre-mixed solutions. Copyright © 2017 Elsevier Ltd. All rights reserved.

Two-dimensional simulation of red blood cell motion near a wall under a lateral force

NASA Astrophysics Data System (ADS)

Hariprasad, Daniel S.; Secomb, Timothy W.

2014-11-01

The motion of a red blood cell suspended in a linear shear flow adjacent to a fixed boundary subject to an applied lateral force directed toward the boundary is simulated. A two-dimensional model is used that represents the viscous and elastic properties of normal red blood cells. Shear rates in the range of 100 to 600 s-1 are considered, and the suspending medium viscosity is 1 cP. In the absence of a lateral force, the cell executes a tumbling motion. With increasing lateral force, a transition from tumbling to tank-treading is predicted. The minimum force required to ensure tank-treading increases nonlinearly with the shear rate. Transient swinging motions occur when the force is slightly larger than the transition value. The applied lateral force is balanced by a hydrodynamic lift force resulting from the positive orientation of the long axis of the cell with respect to the wall. In the case of cyclic tumbling motions, the orientation angle takes positive values through most of the cycle, resulting in lift generation. These results are used to predict the motion of a cell close to the outer edge of the cell-rich core region that is generated when blood flows in a narrow tube. In this case, the lateral force is generated by shear-induced dispersion, resulting from cell-cell interactions in a region with a concentration gradient. This force is estimated using previous data on shear-induced dispersion. The cell is predicted to execute tank-treading motions at normal physiological hematocrit levels, with the possibility of tumbling at lower hematocrit levels.

Fluid-structure interaction simulations of the Fontan procedure using variable wall properties.

PubMed

Long, C C; Hsu, M-C; Bazilevs, Y; Feinstein, J A; Marsden, A L

2012-05-01

Children born with single ventricle heart defects typically undergo a staged surgical procedure culminating in a total cavopulmonary connection (TCPC) or Fontan surgery. The goal of this work was to perform physiologic, patient-specific hemodynamic simulations of two post-operative TCPC patients by using fluid-structure interaction (FSI) simulations. Data from two patients are presented, and post-op anatomy is reconstructed from MRI data. Respiration rate, heart rate, and venous pressures are obtained from catheterization data, and inflow rates are obtained from phase contrast MRI data and are used together with a respiratory model. Lumped parameter (Windkessel) boundary conditions are used at the outlets. We perform FSI simulations by using an arbitrary Lagrangian-Eulerian finite element framework to account for motion of the blood vessel walls in the TCPC. This study is the first to introduce variable elastic properties for the different areas of the TCPC, including a Gore-Tex conduit. Quantities such as wall shear stresses and pressures at critical locations are extracted from the simulation and are compared with pressure tracings from clinical data as well as with rigid wall simulations. Hepatic flow distribution and energy efficiency are also calculated and compared for all cases. There is little effect of FSI on pressure tracings, hepatic flow distribution, and time-averaged energy efficiency. However, the effect of FSI on wall shear stress, instantaneous energy efficiency, and wall motion is significant and should be considered in future work, particularly for accurate prediction of thrombus formation. Copyright © 2012 John Wiley & Sons, Ltd.

Vortex Structure Effects on Impingement, Effusion, and Cross Flow Cooling of a Double Wall Configuration

NASA Astrophysics Data System (ADS)

Ligrani, P. M.

2018-03-01

A variety of different types of vortices and vortex structures have important influences on thermal protection, heat transfer augmentation, and cooling performance of impingement cooling, effusion cooling, and cross flow cooling. Of particular interest are horseshoe vortices, which form around the upstream portions of effusion coolant concentrations just after they exit individual holes, hairpin vortices, which develop nearby and adjacent to effusion coolant trajectories, and Kelvin-Helmholtz vortices which form within the shear layers that form around each impingement cooling jet. The influences of these different vortex structures are described as they affect and alter the thermal performance of effusion cooling, impingement cooling, and cross flow cooling, as applied to a double wall configuration.

Cyclic Behavior of Low Rise Concrete Shear Walls Containing Recycled Coarse and Fine Aggregates.

PubMed

Qiao, Qiyun; Cao, Wanlin; Qian, Zhiwei; Li, Xiangyu; Zhang, Wenwen; Liu, Wenchao

2017-12-07

In this study, the cyclic behaviors of low rise concrete shear walls using recycled coarse or fine aggregates were investigated. Eight low rise Recycled Aggregates Concrete (RAC) shear wall specimens were designed and tested under a cyclic loading. The following parameters were varied: replacement percentages of recycled coarse or fine aggregates, reinforcement ratio, axial force ratio and X-shaped rebars brace. The failure characteristics, hysteretic behavior, strength and deformation capacity, strain characteristics and stiffness were studied. Test results showed that the using of the Recycled Coarse Aggregates (RCA) and its replacement ratio had almost no influence on the mechanical behavior of the shear wall; however, the using of Recycled Fine Aggregates (RFA) had a certain influence on the ductility of the shear wall. When the reinforcement ratio increased, the strength and ductility also increased. By increasing the axial force ratio, the strength increased but the ductility decreased significantly. The encased brace had a significant effect on enhancing the RAC shear walls. The experimental maximum strengths were evaluated with existing design codes, it was indicated that the strength evaluation of the low rise RAC shear walls can follow the existing design codes of the conventional concrete shear walls.

Material flow data for numerical simulation of powder injection molding

NASA Astrophysics Data System (ADS)

Duretek, I.; Holzer, C.

2017-01-01

The powder injection molding (PIM) process is a cost efficient and important net-shape manufacturing process that is not completely understood. For the application of simulation programs for the powder injection molding process, apart from suitable physical models, exact material data and in particular knowledge of the flow behavior are essential in order to get precise numerical results. The flow processes of highly filled polymers are complex. Occurring effects are very hard to separate, like shear flow with yield stress, wall slip, elastic effects, etc. Furthermore, the occurrence of phase separation due to the multi-phase composition of compounds is quite probable. In this work, the flow behavior of a 316L stainless steel feedstock for powder injection molding was investigated. Additionally, the influence of pre-shearing on the flow behavior of PIM-feedstocks under practical conditions was examined and evaluated by a special PIM injection molding machine rheometer. In order to have a better understanding of key factors of PIM during the injection step, 3D non-isothermal numerical simulations were conducted with a commercial injection molding simulation software using experimental feedstock properties. The simulation results were compared with the experimental results. The mold filling studies amply illustrate the effect of mold temperature on the filling behavior during the mold filling stage. Moreover, the rheological measurements showed that at low shear rates no zero shear viscosity was observed, but instead the viscosity further increased strongly. This flow behavior could be described with the Cross-WLF approach with Herschel-Bulkley extension very well.

Computing nonhydrostatic shallow-water flow over steep terrain

USGS Publications Warehouse

Denlinger, R.P.; O'Connell, D. R. H.

2008-01-01

Flood and dambreak hazards are not limited to moderate terrain, yet most shallow-water models assume that flow occurs over gentle slopes. Shallow-water flow over rugged or steep terrain often generates significant nonhydrostatic pressures, violating the assumption of hydrostatic pressure made in most shallow-water codes. In this paper, we adapt a previously published nonhydrostatic granular flow model to simulate shallow-water flow, and we solve conservation equations using a finite volume approach and an Harten, Lax, Van Leer, and Einfeldt approximate Riemann solver that is modified for a sloping bed and transient wetting and drying conditions. To simulate bed friction, we use the law of the wall. We test the model by comparison with an analytical solution and with results of experiments in flumes that have steep (31??) or shallow (0.3??) slopes. The law of the wall provides an accurate prediction of the effect of bed roughness on mean flow velocity over two orders of magnitude of bed roughness. Our nonhydrostatic, law-of-the-wall flow simulation accurately reproduces flume measurements of front propagation speed, flow depth, and bed-shear stress for conditions of large bed roughness. ?? 2008 ASCE.

Direct measurement of wall slip and slip layer thickness of non-Brownian hard-sphere suspensions in rectangular channel flows

NASA Astrophysics Data System (ADS)

Jesinghausen, Steffen; Weiffen, Rene; Schmid, Hans-Joachim

2016-09-01

Wall slip is a long-known phenomenon in the field of rheology. Nevertheless, the origin and the evolution are not completely clear yet. Regarding suspensions, the effect becomes even more complicated, because different mechanisms like pure slip or slip due to particle migration have to be taken into account. Furthermore, suspensions themselves show many flow anomalies and the isolation of slip is complicated. In order to develop working physical models, further insight is necessary. In this work, we measured experimentally the wall slip velocities of different highly filled suspensions in a rectangular slit die directly with respect to the particle concentration and the particle size. The slip velocities were obtained using a particle image velocimetry (PIV) system. The suspensions consisting of a castor oil-cinnamon oil blend and PMMA particles were matched in terms of refractive indexes to appear transparent. Hereby, possible optical path lengths larger than 15 mm were achieved. The slip velocities were found to be in a quadratic relation to the wall shear stress. Furthermore, the overall flow rate as well as the particle concentration has a direct influence on the slip. Concerning the shear stress, there seem to be two regions of slip with different physical characteristics. Furthermore, we estimated the slip layer thickness directly from the velocity profiles and propose a new interpretation. The PIV technique is used to investigate the viscosity and implicit the concentration profile in the slit die. It is shown that the particle migration process is quite fast.

Electrochemical wall shear rate microscopy of collapsing bubbles

NASA Astrophysics Data System (ADS)

Reuter, Fabian; Mettin, Robert

2018-06-01

An electrochemical high-speed wall shear raster microscope is presented. It involves chronoamperometric measurements on a microelectrode that is flush-mounted in a submerged test specimen. Wall shear rates are derived from the measured microelectrode signal by numerically solving a convection-diffusion equation with an optimization approach. This way, the unsteady wall shear rates from the collapse of a laser pulse seeded cavitation bubble close to a substrate are measured. By planar scanning, they are resolved in high spatial resolution. The wall shear rates are related to the bubble dynamics via synchronized high-speed imaging of the bubble shape.

Inertial flow regimes of the suspension of finite size particles

NASA Astrophysics Data System (ADS)

Lashgari, Iman; Picano, Francesco; Brandt, Luca

2015-03-01

We study inertial flow regimes of the suspensions of finite size neutrally buoyant particles. These suspensions experience three different regimes by varying the Reynolds number, Re , and particle volume fraction, Φ. At low values of Re and Φ, flow is laminar-like where viscous stress is the dominating term in the stress budget. At high Re and relatively small Φ, the flow is turbulent-like where Reynolds stress has the largest contribution to the total stress. At high Φ, the flow regime is as a form of inertial shear-thickening characterized by a significant enhancement in the wall shear stress not due to the increment of Reynolds stress but to the particle stress. We further analyze the local behavior of the suspension in the three different regimes by studying the particle dispersion and collisions. Turbulent cases shows higher level of particle dispersion and higher values of the collision kernel (the radial distribution function times the particle relative velocity as a function of the distance between the particles) than those of the inertial shear-thickening regimes providing additional evidence of two different transport mechanisms in the Bagnoldian regime. Support from the European Research Council (ERC) is acknowledged.

Nonuniform flow in soft glasses of colloidal rods

NASA Astrophysics Data System (ADS)

Dhont, J. K. G.; Kang, K.; Kriegs, H.; Danko, O.; Marakis, J.; Vlassopoulos, D.

2017-04-01

Despite our reasonably advanced understanding of the dynamics and flow of glasses made of spherical colloids, the role of shape, i.e., the respective behavior of glasses formed by rodlike, particles is virtually unexplored. Recently, long, thin and highly charged rods (fd-virus particles) were found to vitrify in aqueous suspensions at low ionic strength [Phys. Rev. Lett. 110, 015901 (2013), 10.1103/PhysRevLett.110.015901]. The glass transition of these long-ranged repulsive rods occurs at a concentration far above the isotropic-nematic coexistence region and is characterized by the unique arrest of both the dynamics of domains that constitute the chiral-nematic orientational texture, as well as individual rods inside the domains. Hence, two relevant length scales exist: the domain size of a few hundreds of microns, and the rod-cage size of a few microns, inside the domains. We show that the unique dual dynamic arrest and the existing of two widely separated length scales imparts an unprecedented, highly heterogeneous flow behavior with three distinct signatures. Beyond a weak stress plateau at very small shear rates that characterizes the glass, the kinetic arrest of the domain dynamics gives rise to internal fracture, as a result of domain-domain interactions, as well as wall partial slip. It is shown that, on increasing the shear rate, the fractured plug flow changes to a shear-banded flow profile due to the stress response of the kinetically arrested aligned rods within the domains. Shear-gradient banding occurs due to the strong thinning of the uniform chiral-nematic phase within the domains, i.e., complying with the classic shear-banding scenario, giving rise to a stress plateau in the flow curve. Finally, a linear (uniform) velocity profile is found at the highest shear rates. Vorticity banding is also observed at intermediate and high shear rates. These results point to the crucial role of particle shape in tailoring the flow properties of dense colloidal suspensions. Moreover, they strongly support the argument that the origin of shear banding in soft-particle glasses with long-ranged repulsive interactions is fundamentally different from that of hard-particle glasses with short-ranged repulsive interactions.

Suppression of Helmholtz resonance using inside acoustic liner

NASA Astrophysics Data System (ADS)

Hong, Zhiliang; Dai, Xiwen; Zhou, Nianfa; Sun, Xiaofeng; Jing, Xiaodong

2014-08-01

When a Helmholtz resonator is exposed to grazing flow, an unstable shear layer at the opening can cause the occurrence of acoustic resonance under appropriate conditions. In this paper, in order to suppress the flow-induced resonance, the effects of inside acoustic liners placed on the side wall or the bottom of a Helmholtz resonator are investigated. Based on the one-dimensional sound propagation theory, the time domain impedance model of a Helmholtz resonator with inside acoustic liner is derived, and then combined with a discrete vortex model the resonant behavior of the resonator under grazing flow is simulated. Besides, an experiment is conducted to validate the present model, showing significant reduction of the peak sound pressure level achieved by the use of the side-wall liners. And the simulation results match reasonably well with the experimental data. The present results reveal that the inside acoustic liner can not only absorb the resonant sound pressure, but also suppress the fluctuation motion of the shear layer over the opening of the resonator. In all, the impact of the acoustic liners is to dampen the instability of the flow-acoustic coupled system. This demonstrates that it is a convenient and effective method for suppressing Helmholtz resonance by using inside acoustic liner.

Instability mechanisms and transition scenarios of spiral turbulence in Taylor-Couette flow.

PubMed

Meseguer, Alvaro; Mellibovsky, Fernando; Avila, Marc; Marques, Francisco

2009-10-01

Alternating laminar and turbulent helical bands appearing in shear flows between counterrotating cylinders are accurately computed and the near-wall instability phenomena responsible for their generation identified. The computations show that this intermittent regime can only exist within large domains and that its spiral coherence is not dictated by endwall boundary conditions. A supercritical transition route, consisting of a progressive helical alignment of localized turbulent spots, is carefully studied. Subcritical routes disconnected from secondary laminar flows have also been identified.

Biofilms in 3D porous media: Delineating the influence of the pore network geometry, flow and mass transfer on biofilm development.

PubMed

Carrel, Maxence; Morales, Verónica L; Beltran, Mario A; Derlon, Nicolas; Kaufmann, Rolf; Morgenroth, Eberhard; Holzner, Markus

2018-05-01

This study investigates the functional correspondence between porescale hydrodynamics, mass transfer, pore structure and biofilm morphology during progressive biofilm colonization of a porous medium. Hydrodynamics and the structure of both the porous medium and the biofilm are experimentally measured with 3D particle tracking velocimetry and micro X-ray Computed Tomography, respectively. The analysis focuses on data obtained in a clean porous medium after 36 h of biofilm growth. Registration of the particle tracking and X-ray data sets allows to delineate the interplay between porous medium geometry, hydrodynamic and mass transfer processes on the morphology of the developing biofilm. A local analysis revealed wide distributions of wall shear stresses and concentration boundary layer thicknesses. The spatial distribution of the biofilm patches uncovered that the wall shear stresses controlled the biofilm development. Neither external nor internal mass transfer limitations were noticeable in the considered system, consistent with the excess supply of nutrient and electron acceptors. The wall shear stress remained constant in the vicinity of the biofilm but increased substantially elsewhere. Copyright © 2018 Elsevier Ltd. All rights reserved.

Parametric Study of Wall Shear Stress in Idealized Avian Airways

NASA Astrophysics Data System (ADS)

Farnsworth, Michael S.; Riede, Tobias; Thomson, Scott L.

2017-11-01

Because wall shear stress (WSS) affects cell response, WSS patterns in avian respiratory airways may be related to the origin of the syrinx and corresponding voice-producing tissue structures (e.g., membranes or vocal folds) in birds. To explore possible linkages between WSS patterns and the locations of avian voice-producing structures, a computational model of flow through an idealized portion of the avian respiratory airway, including trachea and primary bronchi sections, has been developed. The flow is governed by the Navier-Stokes equations, with velocity boundary conditions derived from pressure-flow data in an adult zebra finch during quiet respiration. Geometric parameters such as tracheal/bronchial diameter and length, as well as bronchial branching angle, are parametrically varied based on data for different avian species. Simulation results predict elevated WSS in the vicinity of the tracheobronchial juncture, the location at which voice-producing tissues are found in avian species. In this presentation, the model will be described and spatial distributions of WSS during inspiration and expiration will be presented and compared for different geometric configurations and respiration rates and waveforms. Funding for this project from the Gordon and Betty Moore Foundation (Grant 4498) is gratefully acknowledged.

Characterization of mechano-sensitive nano-containers for targeted vasodilation

NASA Astrophysics Data System (ADS)

Buscema, Marzia; Deyhle, Hans; Pfohl, Thomas; Hieber, Simone E.; Zumbuehl, Andreas; Müller, Bert

2016-04-01

Cardiovascular diseases are the worldwide number one cause of mortality. The blood flow in diseased human coronary arteries differs from the blood flow in the healthy vessels. This fact should be used for designing targeted localized delivery of vasodilators with a purely physical drug release trigger. Thus, we have proposed mechano-sensitive liposomes as mechano-sensitive containers. One has to tailor the liposome's properties, so that containers are stable under physiological conditions in health, but release their cargo near the constricted vessels at body temperature. In order to determine the shear stress threshold for release, both the morphology of the healthy and diseased human arteries and the mechanical property of the liposomes have to be known. We have shown that micro computed tomography (μCT) techniques allow visualizing the lumen of human coronary arteries and provide the basis for flow simulations to extract the wall shear stress of healthy and stenosed regions in human coronary arteries. The behavior of the mechano-sensitive liposomes is currently investigated by means of microfluidics and spatially resolved small-angle X-ray scattering. The liposomes are injected into micro-channels mimicking in vivo situation. The scattering signal from the liposomes reveals information about their size, shape, and wall thickness.

Time evolution of shear-induced particle margination and migration in a cellular suspension

NASA Astrophysics Data System (ADS)

Qi, Qin M.; Shaqfeh, Eric S. G.

2016-11-01

The inhomogeneous center-of-mass distributions of red blood cells and platelets normal to the flow direction in small vessels play a significant role in hemostasis and drug delivery. Under pressure-driven flow in channels, the migration of deformable red blood cells at steady state is characterized by a cell-free or Fahraeus-Lindqvist layer near the vessel wall. Rigid particles such as platelets, however, "marginate" and thus develop a near-wall excess concentration. In order to evaluate the role of branching and design suitable microfluidic devices, it is important to investigate the time evolution of particle margination and migration from a non-equilibrium state and determine the corresponding entrance lengths. From a mechanistic point of view, deformability-induced hydrodynamic lift and shear-induced diffusion are essential mechanisms for the cross-flow migration and margination. In this talk, we determine the concentration distribution of red blood cells and platelets by solving coupled Boltzmann advection-diffusion equations for both species and explore their time evolution. We verify our model by comparing with large-scale, multi-cell simulations and experiments. Our Boltzmann collision theory serves as a fast alternative to large-scale simulations.

Extrema principles of entrophy production and energy dissipation in fluid mechanics

NASA Technical Reports Server (NTRS)

Horne, W. Clifton; Karamcheti, Krishnamurty

1988-01-01

A survey is presented of several extrema principles of energy dissipation as applied to problems in fluid mechanics. An exact equation is derived for the dissipation function of a homogeneous, isotropic, Newtonian fluid, with terms associated with irreversible compression or expansion, wave radiation, and the square of the vorticity. By using entropy extrema principles, simple flows such as the incompressible channel flow and the cylindrical vortex are identified as minimal dissipative distributions. The principal notions of stability of parallel shear flows appears to be associated with a maximum dissipation condition. These different conditions are consistent with Prigogine's classification of thermodynamic states into categories of equilibrium, linear nonequilibrium, and nonlinear nonequilibrium thermodynamics; vortices and acoustic waves appear as examples of dissipative structures. The measurements of a typical periodic shear flow, the rectangular wall jet, show that direct measurements of the dissipative terms are possible.

Experimental evidence of a helical, supercritical instability in pipe flow of shear thinning fluids

NASA Astrophysics Data System (ADS)

Picaut, L.; Ronsin, O.; Caroli, C.; Baumberger, T.

2017-08-01

We study experimentally the flow stability of entangled polymer solutions extruded through glass capillaries. We show that the pipe flow becomes linearly unstable beyond a critical value (Wic≃5 ) of the Weissenberg number, via a supercritical bifurcation which results in a helical distortion of the extrudate. We find that the amplitude of the undulation vanishes as the aspect ratio L /R of the capillary tends to zero, and saturates for large L /R , indicating that the instability affects the whole pipe flow, rather than the contraction or exit regions. These results, when compared to previous theoretical and experimental works, lead us to argue that the nature of the instability is controlled by the level of shear thinning of the fluids. In addition, we provide strong hints that the nonlinear development of the instabiilty is mitigated, in our system, by the gradual emergence of gross wall slip.

Method and apparatus for strip casting

DOEpatents

Follstaedt, Donald W.; Powell, John C.; Sussman, Richard C.; Williams, Robert S.

1991-01-01

Casting nozzles will provide improved flow conditions with the parameters controlled according to the present invention. The gap relationships between the nozzle slot and exit orifice must be controlled in combination with converging exit passageway to provide a smooth flow without shearing and turbulence in the stream. The nozzle lips are also rounded to improve flow and increase refractory life of the lips of the nozzle. The tundish walls are tapered to provide improve flow for supplying the melt to the nozzle. The nozzle is located about 45.degree. below top dead center for optimum conditions.

Toward a structural understanding of turbulent drag reduction: nonlinear coherent states in viscoelastic shear flows.

PubMed

Stone, Philip A; Waleffe, Fabian; Graham, Michael D

2002-11-11

Nontrivial steady flows have recently been found that capture the main structures of the turbulent buffer layer. We study the effects of polymer addition on these "exact coherent states" (ECS) in plane Couette flow. Despite the simplicity of the ECS flows, these effects closely mirror those observed experimentally: Structures shift to larger length scales, wall-normal fluctuations are suppressed while streamwise ones are enhanced, and drag is reduced. The mechanism underlying these effects is elucidated. These results suggest that the ECS are closely related to buffer layer turbulence.

Suppression of flow pulsation activity by relaxation process of additive effect on viscous media transport

NASA Astrophysics Data System (ADS)

Kharlamov, S.; Dedeyev, P.; Meucci, L.; Shenderova, I.; Manastirniy, A.; Usenko, M.

2015-11-01

The article presents the analysis of the processes occurring together with the turbulent transfer of impulse in mixture of hydrocarbon fluid and polymer solutions (anti-turbulent additives). The study evaluates complex shear flows by popular theoretical and practical methods. Understanding of hydrodynamic and dissipative effects of laminar-turbulent transition tightening and turbulence suppression is provided. The peculiarities of "thin" flow structure in pipeline zones with complex shape walls are evaluated. Recommendations to forecast the local flow parameters, calculation of hydraulic resistance are given.

Smooth- and rough-wall boundary layer structure from high spatial range particle image velocimetry

NASA Astrophysics Data System (ADS)

Squire, D. T.; Morrill-Winter, C.; Hutchins, N.; Marusic, I.; Schultz, M. P.; Klewicki, J. C.

2016-10-01

Two particle image velocimetry arrangements are used to make true spatial comparisons between smooth- and rough-wall boundary layers at high Reynolds numbers across a very wide range of streamwise scales. Together, the arrangements resolve scales ranging from motions on the order of the Kolmogorov microscale to those longer than twice the boundary layer thickness. The rough-wall experiments were obtained above a continuous sandpaper sheet, identical to that used by Squire et al. [J. Fluid Mech. 795, 210 (2016), 10.1017/jfm.2016.196], and cover a range of friction and equivalent sand-grain roughness Reynolds numbers (12 000 ≲δ+≲ 18000, 62 ≲ks+≲104 ). The smooth-wall experiments comprise new and previously published data spanning 6500 ≲δ+≲17 000 . Flow statistics from all experiments show similar Reynolds number trends and behaviors to recent, well-resolved hot-wire anemometry measurements above the same rough surface. Comparisons, at matched δ+, between smooth- and rough-wall two-point correlation maps and two-point magnitude-squared coherence maps demonstrate that spatially the outer region of the boundary layer is the same between the two flows. This is apparently true even at wall-normal locations where the total (inner-normalized) energy differs between the smooth and rough wall. Generally, the present results provide strong support for Townsend's [The Structure of Turbulent Shear Flow (Cambridge University Press, Cambridge, 1956), Vol. 1] wall-similarity hypothesis in high Reynolds number fully rough boundary layer flows.

Left Ventricular Trabeculations Decrease the Wall Shear Stress and Increase the Intra-Ventricular Pressure Drop in CFD Simulations

PubMed Central

Sacco, Federica; Paun, Bruno; Lehmkuhl, Oriol; Iles, Tinen L.; Iaizzo, Paul A.; Houzeaux, Guillaume; Vázquez, Mariano; Butakoff, Constantine; Aguado-Sierra, Jazmin

2018-01-01

The aim of the present study is to characterize the hemodynamics of left ventricular (LV) geometries to examine the impact of trabeculae and papillary muscles (PMs) on blood flow using high performance computing (HPC). Five pairs of detailed and smoothed LV endocardium models were reconstructed from high-resolution magnetic resonance images (MRI) of ex-vivo human hearts. The detailed model of one LV pair is characterized only by the PMs and few big trabeculae, to represent state of art level of endocardial detail. The other four detailed models obtained include instead endocardial structures measuring ≥1 mm2 in cross-sectional area. The geometrical characterizations were done using computational fluid dynamics (CFD) simulations with rigid walls and both constant and transient flow inputs on the detailed and smoothed models for comparison. These simulations do not represent a clinical or physiological scenario, but a characterization of the interaction of endocardial structures with blood flow. Steady flow simulations were employed to quantify the pressure drop between the inlet and the outlet of the LVs and the wall shear stress (WSS). Coherent structures were analyzed using the Q-criterion for both constant and transient flow inputs. Our results show that trabeculae and PMs increase the intra-ventricular pressure drop, reduce the WSS and disrupt the dominant single vortex, usually present in the smoothed-endocardium models, generating secondary small vortices. Given that obtaining high resolution anatomical detail is challenging in-vivo, we propose that the effect of trabeculations can be incorporated into smoothed ventricular geometries by adding a porous layer along the LV endocardial wall. Results show that a porous layer of a thickness of 1.2·10−2 m with a porosity of 20 kg/m2 on the smoothed-endocardium ventricle models approximates the pressure drops, vorticities and WSS observed in the detailed models. PMID:29760665

Experimental Investigation of the Near Wall Flow Structure of a Low Reynolds Number 3-D Turbulent Boundary Layer

NASA Technical Reports Server (NTRS)

Fleming, J. L.; Simpson, R. L.

1997-01-01

Laser Doppler velocimetry (LDV) measurements and hydrogen bubble flow visualization techniques were used to examine the near-wall flow structure of 2D and 3D turbulent boundary layers (TBLs) over a range of low Reynolds numbers. The goals of this research were (1) an increased understanding of the flow physics in the near wall region of turbulent boundary layers,(2) to observe and quantify differences between 2D and 3D TBL flow structures, and (3) to document Reynolds number effects for 3D TBLs. The LDV data have provided results detailing the turbulence structure of the 2D and 3D TBLs. These results include mean Reynolds stress distributions, flow skewing results, and U and V spectra. Effects of Reynolds number for the 3D flow were also examined. Comparison to results with the same 3D flow geometry but at a significantly higher Reynolds number provided unique insight into the structure of 3D TBLs. While the 3D mean and fluctuating velocities were found to be highly dependent on Reynolds number, a previously defined shear stress parameter was discovered to be invariant with Reynolds number. The hydrogen bubble technique was used as a flow visualization tool to examine the near-wall flow structure of 2D and 3D TBLs. Both the quantitative and qualitative results displayed larger turbulent fluctuations with more highly concentrated vorticity regions for the 2D flow.

Coherent structures in a supersonic complex nozzle

NASA Astrophysics Data System (ADS)

Magstadt, Andrew; Berry, Matthew; Glauser, Mark

2016-11-01

The jet flow from a complex supersonic nozzle is studied through experimental measurements. The nozzle's geometry is motivated by future engine designs for high-performance civilian and military aircraft. This rectangular jet has a single plane of symmetry, an additional shear layer (referred to as a wall jet), and an aft deck representative of airframe integration. The core flow operates at a Mach number of Mj , c = 1 . 6 , and the wall jet is choked (Mj , w = 1 . 0). This high Reynolds number jet flow is comprised of intense turbulence levels, an intricate shock structure, shear and boundary layers, and powerful corner vortices. In the present study, stereo PIV measurements are simultaneously sampled with high-speed pressure measurements, which are embedded in the aft deck, and far-field acoustics in the anechoic chamber at Syracuse University. Time-resolved schlieren measurements have indicated the existence of strong flow events at high frequencies, at a Strouhal number of St = 3 . 4 . These appear to result from von Kàrmàn vortex shedding within the nozzle and pervade the entire flow and acoustic domain. Proper orthogonal decomposition is applied on the current data to identify coherent structures in the jet and study the influence of this vortex street. AFOSR Turbulence and Transition Program (Grant No. FA9550-15-1-0435) with program managers Dr. I. Leyva and Dr. R. Ponnappan.

Hepatic perfusion changes in mice livers with developing colorectal cancer metastases.

PubMed

Kruskal, Jonathan B; Thomas, Peter; Kane, Robert A; Goldberg, S Nahum

2004-05-01

To evaluate whether intrahepatic flow alterations occur during formation of hepatic colorectal cancer metastases and to identify possible causes of these alterations. Intravital imaging of exteriorized livers was performed in 72 live mice. Three groups of mice were studied: a sham-operated control group (n = 24), a group with nonmetastasizing subcutaneous gliomas (n = 24), and a group with developing hepatic CX-1 colon cancer metastases (n = 24). Microvascular flow parameters, leukocyte-endothelial interactions, and wall shear stress were directly measured in hepatic sinusoids and postsinusoidal venules at 2-day intervals prior to and during the development of metastases. The Kruskal-Wallis test was used initially to test for overall equality of medians in each data group. Single posttest comparisons of independent samples were performed with the Mann-Whitney test, with an overall statistical significance of .05. Prior to the development of visible colorectal cancer metastases, significant (P <.05) reductions occurred in sinusoidal and postsinusoidal flow and wall shear rates, coupled with increased leukocyte rolling and adherence. With tumor growth, flow was further compromised in 92% of tumors larger than 0.5 mm in diameter by extrinsic compression of sinusoids and portal venules and narrowing caused by adherent leukocytes. Significant intrahepatic flow alterations occur in mouse livers prior to growth of visible metastases and provide a rational explanation for elevation in the Doppler perfusion index that occurs prior to tumor formation.

Estimating the hemodynamic impact of interventional treatments of aneurysms: numerical simulation with experimental validation: technical case report.

PubMed

Acevedo-Bolton, Gabriel; Jou, Liang-Der; Dispensa, Bradley P; Lawton, Michael T; Higashida, Randall T; Martin, Alastair J; Young, William L; Saloner, David

2006-08-01

The goal of this study was to use phase-contrast magnetic resonance imaging and computational fluid dynamics to estimate the hemodynamic outcome that might result from different interventional options for treating a patient with a giant fusiform aneurysm. We followed a group of patients with giant intracranial aneurysms who have no clear surgical options. One patient demonstrated dramatic aneurysm growth and was selected for further analysis. The aneurysm geometry and input and output flow conditions were measured with contrast-enhanced magnetic resonance angiography and phase-contrast magnetic resonance imaging. The data was imported into a computational fluid dynamics program and the velocity fields and wall shear stress distributions were calculated for the presenting physiological condition and for cases in which the opposing vertebral arteries were either occluded or opened. These models were validated with in vitro flow experiments using a geometrically exact silicone flow phantom. Simulation indicated that altering the flow ratio in the two vertebrals would deflect the main blood jet into the aneurysm belly, and that this would likely reduce the extent of the region of low wall shear stress in the growth zone. Computational fluid dynamics flow simulations in a complex patient-specific aneurysm geometry were validated by in vivo and in vitro phase-contrast magnetic resonance imaging, and were shown to be useful in modeling the likely hemodynamic impact of interventional treatment of the aneurysm.

Wall effects in continuous microfluidic magneto-affinity cell separation.

PubMed

Wu, Liqun; Zhang, Yong; Palaniapan, Moorthi; Roy, Partha

2010-05-01

Continuous microfluidic magneto-affinity cell separator combines unique microscale flow phenomenon with advantageous nanobead properties, to isolate cells with high specificity. Owing to the comparable size of the cell-bead complexes and the microchannels, the walls of the microchannel exert a strong influence on the separation of cells by this method. We present a theoretical and experimental study that provides a quantitative description of hydrodynamic wall interactions and wall rolling velocity of cells. A transient convection model describes the transport of cells in two-phase microfluidic flow under the influence of an external magnetic field. Transport of cells along the microchannel walls is also considered via an additional equation. Results show the variation of cell flux in the fluid phases and the wall as a function of a dimensionless parameter arising in the equations. Our results suggest that conditions may be optimized to maximize cell separation while minimizing contact with the wall surfaces. Experimentally measured cell rolling velocities on the wall indicate the presence of other near-wall forces in addition to fluid shear forces. Separation of a human colon carcinoma cell line from a mixture of red blood cells, with folic acid conjugated 1 microm and 200 nm beads, is reported.

Simulation of Couette flow using conventional Burnett equations with modified slip boundary conditions

NASA Astrophysics Data System (ADS)

Liu, Hualin; Zhao, Wenwen; Chen, Weifang

2016-11-01

Gas or liquid flow through small channels has become more and more popular due to the micro-electro-mechanical systems (MEMS) fabrication technologies such as micro-motors, electrostatic comb-drive, micro-chromatographs, micro-actuators, micro-turbines and micro-pumps, etc. The flow conditions in and around these systems are always recognized as typical transitional regimes. Under these conditions, the mean free path of gas molecules approaches the characteristic scale of the micro-devices itself, and due to the little collisions the heat and momentum cannot equilibrate between the wall and fluids quickly. Couette flow is a simple and critical model in fluid dynamics which focuses on the mechanism of the heat transfer in shear-driven micro-cavities or micro-channels. Despite numerous work on the numerical solutions of the Couette flow, how to propose stable and accurate slip boundary conditions in rarefied flow conditions still remains to be elucidated. In this paper, converged solutions for steady-state micro Couette flows are obtained by using conventional Burnett equations with a set of modified slip boundary conditions. Instead of using the physical variables at the wall, the modified slip conditions use the variables at the edge of the Knudsen layer based on a physically plausible assumption in literature that Knudsen layer has a thickness only in the order of a mean free path and molecules are likely to travel without collision in this layer. Numerical results for non-dimensional wall shear stress and heat flux are compared with those of the DSMC solutions. Although there are not much improvement in the accuracy by using this modified slip conditions, the modified conditions perform much better than the unmodified slip conditions for numerical stabilization. All results show that the set of conventional Burnett equations with second order modified conditions are proved to be an appropriate model for the micro-Couette flows.

Lattice Boltzmann simulation of asymmetric flow in nematic liquid crystals with finite anchoring

NASA Astrophysics Data System (ADS)

Zhang, Rui; Roberts, Tyler; Aranson, Igor S.; de Pablo, Juan J.

2016-02-01

Liquid crystals (LCs) display many of the flow characteristics of liquids but exhibit long range orientational order. In the nematic phase, the coupling of structure and flow leads to complex hydrodynamic effects that remain to be fully elucidated. Here, we consider the hydrodynamics of a nematic LC in a hybrid cell, where opposite walls have conflicting anchoring boundary conditions, and we employ a 3D lattice Boltzmann method to simulate the time-dependent flow patterns that can arise. Due to the symmetry breaking of the director field within the hybrid cell, we observe that at low to moderate shear rates, the volumetric flow rate under Couette and Poiseuille flows is different for opposite flow directions. At high shear rates, the director field may undergo a topological transition which leads to symmetric flows. By applying an oscillatory pressure gradient to the channel, a net volumetric flow rate is found to depend on the magnitude and frequency of the oscillation, as well as the anchoring strength. Taken together, our findings suggest several intriguing new applications for LCs in microfluidic devices.

Wall shear stress as measured in vivo: consequences for the design of the arterial system.

PubMed

Reneman, Robert S; Hoeks, Arnold P G

2008-05-01

Based upon theory, wall shear stress (WSS), an important determinant of endothelial function and gene expression, has been assumed to be constant along the arterial tree and the same in a particular artery across species. In vivo measurements of WSS, however, have shown that these assumptions are far from valid. In this survey we will discuss the assessment of WSS in the arterial system in vivo and present the results obtained in large arteries and arterioles. In vivo WSS can be estimated from wall shear rate, as derived from non-invasively recorded velocity profiles, and whole blood viscosity in large arteries and plasma viscosity in arterioles, avoiding theoretical assumptions. In large arteries velocity profiles can be recorded by means of a specially designed ultrasound system and in arterioles via optical techniques using fluorescent flow velocity tracers. It is shown that in humans mean WSS is substantially higher in the carotid artery (1.1-1.3 Pa) than in the brachial (0.4-0.5 Pa) and femoral (0.3-0.5 Pa) arteries. Also in animals mean WSS varies substantially along the arterial tree. Mean WSS in arterioles varies between about 1.0 and 5.0 Pa in the various studies and is dependent on the site of measurement in these vessels. Across species mean WSS in a particular artery decreases linearly with body mass, e.g., in the infra-renal aorta from 8.8 Pa in mice to 0.5 Pa in humans. The observation that mean WSS is far from constant along the arterial tree implies that Murray's cube law on flow-diameter relations cannot be applied to the whole arterial system. Because blood flow velocity is not constant along the arterial tree either, a square law also does not hold. The exponent in the power law likely varies along the arterial system, probably from 2 in large arteries near the heart to 3 in arterioles. The in vivo findings also imply that in in vitro studies no average shear stress value can be taken to study effects on endothelial cells derived from different vascular areas or from the same artery in different species. The cells have to be studied under the shear stress conditions they are exposed to in real life.