GRC-2013-C-01423

NASA Image and Video Library

2009-04-22

University of Florida, Professor and Director of Interdisciplinary Center for Biotechnology Research Interacting with the Fluids Integration Rack, FIR, Light Microscopy Module, LMM, Ground Integration Unit, GIU, Hardware

GRC-2013-C-01422

NASA Image and Video Library

2009-04-22

University of Florida, Professor and Director of Interdisciplinary Center for Biotechnology Research Interacting with the Fluids Integration Rack, FIR, Light Microscopy Module, LMM, Ground Integration Unit, GIU, Hardware

Acoustic emissions verification testing of International Space Station experiment racks at the NASA Glenn Research Center Acoustical Testing Laboratory

NASA Astrophysics Data System (ADS)

Akers, James C.; Passe, Paul J.; Cooper, Beth A.

2005-09-01

The Acoustical Testing Laboratory (ATL) at the NASA John H. Glenn Research Center (GRC) in Cleveland, OH, provides acoustic emission testing and noise control engineering services for a variety of specialized customers, particularly developers of equipment and science experiments manifested for NASA's manned space missions. The ATL's primary customer has been the Fluids and Combustion Facility (FCF), a multirack microgravity research facility being developed at GRC for the USA Laboratory Module of the International Space Station (ISS). Since opening in September 2000, ATL has conducted acoustic emission testing of components, subassemblies, and partially populated FCF engineering model racks. The culmination of this effort has been the acoustic emission verification tests on the FCF Combustion Integrated Rack (CIR) and Fluids Integrated Rack (FIR), employing a procedure that incorporates ISO 11201 (``Acoustics-Noise emitted by machinery and equipment-Measurement of emission sound pressure levels at a work station and at other specified positions-Engineering method in an essentially free field over a reflecting plane''). This paper will provide an overview of the test methodology, software, and hardware developed to perform the acoustic emission verification tests on the CIR and FIR flight racks and lessons learned from these tests.

The International Space Station as a Research Laboratory: A View to 2010 and Beyond

NASA Technical Reports Server (NTRS)

Uri, John J.; Sotomayor, Jorge L.

2007-01-01

Assembly of International Space Station (ISS) is expected to be complete in 2010, with operations planned to continue through at least 2016. As we move nearer to assembly complete, replanning activities by NASA and ISS International Partners have been completed and the final complement of research facilities on ISS is becoming more certain. This paper will review pans for facilities in the US On-orbit Segment of ISS, including contributions from International Partners, to provide a vision of the research capabilities that will be available starting in 2010. At present, in addition to research capabilities in the Russian segment, the United States Destiny research module houses nine research facilities or racks. These facilities include five multi-purpose EXPRESS racks, two Human Research Facility (HRF) racks, the Microgravity Science Glovebox (MSG), and the Minus Eighty-degree Laboratory Freezer for ISS (MELFI), enabling a wide range of exploration-related applied as well as basic research. In the coming years, additional racks will be launched to augment this robust capability: Combustion Integrated Rack (CIR), Fluids Integrated Rack (FIR), Window Observation Rack Facility (WORF), Microgravity Science Research Rack (MSRR), Muscle Atrophy Research Exercise System (MARES), additional EXPRESS racks and possibly a second MELFI. In addition, EXPRESS Logistics Carriers (ELC) will provide attach points for external payloads. The European Space Agency s Columbus module will contain five research racks and provide four external attach sites. The research racks are Biolab, European Physiology Module (EPM), Fluid Science Lab (FSL), European Drawer System (EDS) and European Transport Carrier (ETC). The Japanese Kibo elements will initially support three research racks, Ryutai for fluid science, Saibo for cell science, and Kobairo for materials research, as well as 10 attachment sites for external payloads. As we look ahead to assembly complete, these new facilities represent a threefold increase from the current research laboratory infrastructure on ISS. In addition, the increase in resident crew size will increase from three to six in 2009, will provide the long-term capacity for completing research on board ISS. Transportation to and from ISS for crew and cargo will be provided by a fleet of vehicles from the United States, Russia, ESA and Japan, including accommodations for thermally-conditioned cargo. The completed ISS will have robust research accommodations to support the multidisciplinary research objective of scientists worldwide.

International Space Station -- Fluid Physics Rack

NASA Technical Reports Server (NTRS)

2000-01-01

The optical bench for the Fluids Integrated Rack section of the Fluids and Combustion Facility (FCF) is shown extracted for servicing and with the optical bench rotated 90 degrees to access the rear elements. The FCF will be installed, in phases, in the Destiny, the U.S. Laboratory Module of the International Space Station (ISS), and will accommodate multiple users for a range of investigations. This is an engineering mockup; the flight hardware is subject to change as designs are refined. The FCF is being developed by the Microgravity Science Division (MSD) at the NASA Glenn Research Center. (Photo credit: NASA/Marshall Space Flight Center)

Microgravity Combustion Science and Fluid Physics Experiments and Facilities for the ISS

NASA Technical Reports Server (NTRS)

Lauver, Richard W.; Kohl, Fred J.; Weiland, Karen J.; Zurawski, Robert L.; Hill, Myron E.; Corban, Robert R.

2001-01-01

At the NASA Glenn Research Center, the Microgravity Science Program supports both ground-based and flight experiment research in the disciplines of Combustion Science and Fluid Physics. Combustion Science research includes the areas of gas jet diffusion flames, laminar flames, burning of droplets and misting fuels, solids and materials flammability, fire and fire suppressants, turbulent combustion, reaction kinetics, materials synthesis, and other combustion systems. The Fluid Physics discipline includes the areas of complex fluids (colloids, gels, foams, magneto-rheological fluids, non-Newtonian fluids, suspensions, granular materials), dynamics and instabilities (bubble and drop dynamics, magneto/electrohydrodynamics, electrochemical transport, geophysical flows), interfacial phenomena (wetting, capillarity, contact line hydrodynamics), and multiphase flows and phase changes (boiling and condensation, heat transfer, flow instabilities). A specialized International Space Station (ISS) facility that provides sophisticated research capabilities for these disciplines is the Fluids and Combustion Facility (FCF). The FCF consists of the Combustion Integrated Rack (CIR), the Fluids Integrated Rack (FIR) and the Shared Accommodations Rack and is designed to accomplish a large number of science investigations over the life of the ISS. The modular, multiuser facility is designed to optimize the science return within the available resources of on-orbit power, uplink/downlink capacity, crew time, upmass/downmass, volume, etc. A suite of diagnostics capabilities, with emphasis on optical techniques, will be provided to complement the capabilities of the subsystem multiuser or principal investigator-specific experiment modules. The paper will discuss the systems concept, technical capabilities, functionality, and the initial science investigations in each discipline.

The Fluids Integrated Rack and Light Microscopy Module Integrated Capabilities

NASA Technical Reports Server (NTRS)

Motil, Susan M.; Gati, Frank; Snead, John H.; Hill, Myron E.; Griffin, DeVon W.

2003-01-01

The Fluids Integrated Rack (FIR), a facility class payload, and the Light Microscopy Module (LMM), a subrack payload, are scheduled to be launched in 2005. The LMM integrated into the FIR will provide a unique platform for conducting fluids and biological experiments on ISS. The FIR is a modular, multi-user scientific research facility that will fly in the U.S. laboratory module, Destiny, of the International Space Station (ISS). The first payload in the FIR will be the Light Microscopy Module (LMM). The LMM is planned as a remotely controllable, automated, on-orbit microscope subrack facility, allowing flexible scheduling and control of fluids and biology experiments within the FIR. Key diagnostic capabilities for meeting science requirements include video microscopy to observe microscopic phenomena and dynamic interactions, interferometry to make thin film measurements with nanometer resolution, laser tweezers for particle manipulation, confocal microscopy to provide enhanced three-dimensional visualization of structures, and spectrophotometry to measure photonic properties of materials. The LMM also provides experiment sample containment for frangibles and fluids. This paper will provide a description of the current FIR and LMM designs, planned capabilities and key features. In addition a brief description of the initial five experiments planned for LMM/FIR will be provided.

International Space Station -- Fluid Physics Ra;ck

NASA Technical Reports Server (NTRS)

2000-01-01

The optical bench for the Fluids Integrated Rack section of the Fluids and Combustion Facility (FCF) is shown extracted for servicing and with the optical bench rotated 90 degrees for access to the rear elements. The FCF will be installed, in phases, in the Destiny, the U.S. Laboratory Module of the International Space Station (ISS), and will accommodate multiple users for a range of investigations. This is an engineering mockup; the flight hardware is subject to change as designs are refined. The FCF is being developed by the Microgravity Science Division (MSD) at the NASA Glenn Research Center. (Photo credit: NASA/Marshall Space Flight Center)

Hopkins in U.S. Lab with FIR/FCF

NASA Image and Video Library

2013-10-15

ISS037-E-013951 (14 Oct. 2013) --- NASA astronaut Michael Hopkins, Expedition 37 flight engineer, works at the Light Microscopy Module (LMM) in the Fluids Integrated Rack / Fluids Combustion Facility (FIR/FCF) located in the Destiny laboratory of the International Space Station.

The Light Microscopy Module: An On-Orbit Multi-User Microscope Facility

NASA Technical Reports Server (NTRS)

Motil, Susan M.; Snead, John H.

2002-01-01

The Light Microscopy Module (LMM) is planned as a remotely controllable on-orbit microscope subrack facility, allowing flexible scheduling and operation of fluids and biology experiments within the Fluids and Combustion Facility (FCF) Fluids Integrated Rack (FIR) on the International Space Station (ISS). The LMM will be the first integrated payload with the FIR to conduct four fluid physics experiments. A description of the LMM diagnostic capabilities, including video microscopy, interferometry, laser tweezers, confocal, and spectrophotometry, will be provided.

Light Microscopy Module: On-Orbit Microscope Planned for the Fluids Integrated Rack on the International Space Station

NASA Technical Reports Server (NTRS)

Motil, Susan M.

2002-01-01

The Light Microscopy Module (LMM) is planned as a remotely controllable, automated, on-orbit facility, allowing flexible scheduling and control of physical science and biological science experiments within the Fluids Integrated Rack (FIR) on the International Space Station. Initially four fluid physics experiments in the FIR will use the LMM the Constrained Vapor Bubble, the Physics of Hard Spheres Experiment-2, Physics of Colloids in Space-2, and Low Volume Fraction Entropically Driven Colloidal Assembly. The first experiment will investigate heat conductance in microgravity as a function of liquid volume and heat flow rate to determine, in detail, the transport process characteristics in a curved liquid film. The other three experiments will investigate various complementary aspects of the nucleation, growth, structure, and properties of colloidal crystals in microgravity and the effects of micromanipulation upon their properties.

Microgravity Emissions Laboratory Testing of the Light Microscopy Module Control Box Fan

NASA Technical Reports Server (NTRS)

McNelis, Anne M.; Samorezov, Sergey; Haecker, Anthony H.

2003-01-01

The Microgravity Emissions Laboratory (MEL) was developed at the NASA Glenn Research Center for the characterization, simulation, and verification of the International Space Station (ISS) microgravity environment. This Glenn lab was developed in support of the Fluids and Combustion Facility (FCF). The MEL is a six-degrees-of-freedom inertial measurement system that can characterize the inertial response forces (emissions) of components, subrack payloads, or rack-level payloads down to 10 7g. The inertial force output data generated from the steady-state or transient operations of the test article are used with finite element analysis, statistical energy analysis, and other analysis tools to predict the on-orbit environment at specific science or rack interface locations. Customers of the MEL have used benefits in isolation performance testing in defining available attenuation during the engineering hardware design phase of their experiment s development. The Light Microscopy Module (LMM) Control Box (LCB) fan was tested in the MEL in June and July of 2002. The LMM is planned as a remotely controllable on-orbit microscope subrack facility that will be accommodated in an FCF Fluids Integrated Rack on the ISS. The disturbances measured in the MEL test resulted from operation of the air-circulation fan within the LCB. The objectives of the testing were (1) to identify an isolator to be added to the LCB fan assembly to reduce fan-speed harmonics and (2) to identify the fan-disturbance forcing functions for use in rack-response analysis of the LMM and Fluids Integrated Rack facility. This report describes the MEL, the testing process, and the results from ground-based MEL LCB fan testing.

The ISS Fluids Integrated Rack (FIR): a Summary of Capabilities

NASA Astrophysics Data System (ADS)

Gati, F.; Hill, M. E.

2002-01-01

The Fluids Integrated Rack (FIR) is a modular, multi-user scientific research facility that will fly in the U.S. laboratory module, Destiny, of the International Space Station (ISS). The FIR will be one of the two racks that will make up the Fluids and Combustion Facility (FCF) - the other being the Combustion Integrated Rack (CIR). The ISS will provide the FCF with the necessary resources, such as power and cooling. While the ISS crew will be available for experiment operations, their time will be limited. The FCF is, therefore, being designed for autonomous operations and remote control operations. Control of the FCF will be primarily through the Telescience Support Center (TSC) at the Glenn Research Center. The FCF is being designed to accommodate a wide range of combustion and fluids physics experiments within the ISS resources and constraints. The primary mission of the FIR, however, is to accommodate experiments from four major fluids physics disciplines: Complex Fluids; Multiphase Flow and Heat Transfer; Interfacial Phenomena; and Dynamics and Stability. The design of the FIR is flexible enough to accommodate experiments from other science disciplines such as Biotechnology. The FIR flexibility is a result of the large volume dedicated for experimental hardware, easily re-configurable diagnostics that allow for unique experiment configurations, and it's customizable software. The FIR will utilize six major subsystems to accommodate this broad scope of fluids physics experiments. The major subsystems are: structural, environmental, electrical, gaseous, command and data management, and imagers and illumination. Within the rack, the FIR's structural subsystem provides an optics bench type mechanical interface for the precise mounting of experimental hardware; including optical components. The back of the bench is populated with FIR avionics packages and light sources. The interior of the rack is isolated from the cabin through two rack doors that are hinged near the top and bottom of the rack. Transmission of micro-gravity disturbances to and from the rack is minimized through the Active Rack Isolation System (ARIS). The environmental subsystem will utilize air and water to remove heat generated by facility and experimental hardware. The air will be circulated throughout the rack and will be cooled by an air-water heat exchanger. Water will be used directly to cool some of the FIR components and will also be available to cool experiment hardware as required. The electrical subsystem includes the Electrical Power Control Unit (EPCU), which provides 28 VDC and 120 VDC power to the facility and the experiment hardware. The EPCU will also provide power management and control functions, as well as fault protection capabilities. The FIR will provide access to the ISS gaseous nitrogen and vacuum systems. These systems are available to support experiment operations such as the purging of experimental cells, creating flows within experimental cells and providing dry conditions where needed. The FIR Command and Data Management subsystem (CDMS) provides command and data handling for both facility and experiment hardware. The Input Output Processor (IOP) provides the overall command and data management functions for the rack including downlinking or writing data to removable drives. The IOP will also monitor the health and status of the rack subsystems. The Image Processing and Storage Units (IPSU) will perform diagnostic control and image data acquisition functions. An IPSU will be able to control a digital camera, receive image data from that camera and process/ compress image data as necessary. The Fluids Science and Avionics Package (FSAP) will provide the primary control over an experiment. The FSAP contains various computer boards/cards that will perform data and control functions. To support the imaging needs, cameras and illumination sources will be available to the investigator. Both color analog and black and white digital cameras with lenses are expected. These cameras will be capable of high resolution and, separately, frame rates up to 32,000 frames per second. Lenses for these cameras will provide both microscopic and macroscopic views. The FIR will provide two illumination sources, a 532 nm Nd:YAG laser and a white light source, both with adjustable power output. The FIR systems are being designed to maximize the amount of science that can be done on-orbit. Experiments will be designed and efficiently operated. Each individual experiment must determine the best configuration of utilizing facility capabilities and resources with augmentation of specific experiment hardware. Efficient operations will be accomplished via a combination of on-orbit physical component change-outs or processing by the crew, and software updates via ground commanding or by the crew. Careful coordination by ground and on-orbit personnel regarding the on-orbit storage and downlinking of image data will also be very important.

Burbank works at the LMM in the FIR/FCF in the U.S. Laboratory

NASA Image and Video Library

2011-12-01

ISS030-E-007428 (1 Dec. 2011) --- NASA astronaut Dan Burbank, Expedition 30 commander, works at the Light Microscopy Module (LMM) in the Fluids Integrated Rack / Fluids Combustion Facility (FIR/FCF) located in the Destiny laboratory of the International Space Station.

Burbank works at the LMM in the FIR/FCF in the U.S. Laboratory

NASA Image and Video Library

2011-12-01

ISS030-E-007426 (1 Dec. 2011) --- NASA astronaut Dan Burbank, Expedition 30 commander, works at the Light Microscopy Module (LMM) in the Fluids Integrated Rack / Fluids Combustion Facility (FIR/FCF) located in the Destiny laboratory of the International Space Station.

Burbank works at the LMM in the FIR/FCF in the U.S. Laboratory

NASA Image and Video Library

2011-12-01

ISS030-E-007429 (1 Dec. 2011) --- NASA astronaut Dan Burbank, Expedition 30 commander, works at the Light Microscopy Module (LMM) in the Fluids Integrated Rack / Fluids Combustion Facility (FIR/FCF) located in the Destiny laboratory of the International Space Station.

FIR sample change

NASA Image and Video Library

2011-10-11

ISS029-E-025108 (11 Oct. 2011) --- NASA astronaut Mike Fossum, Expedition 29 commander, works on the Fluids Integrated Rack/Fluids and Combustion Facility (FIR/FCF), conducting another session with the Preliminary Advanced Colloids Experiment (PACE). Fossum is working at the Light Microscopy Module (LMM) in the Destiny laboratory of the International Space Station.

GRC-2015-C-00903

NASA Image and Video Library

2011-03-15

NASA (Zin Technologies) engineer prepares Advanced Colloid Experiment Heated-2 samples that will be analyzed aboard the International Space Station using the zero-gravity Light Microscopy Module, LMM in the Fluids Integrated Rack, FIR

MWA in U.S. Lab

NASA Image and Video Library

2011-10-17

ISS029-E-029756 (17 Oct. 2011) --- NASA astronaut Mike Fossum, Expedition 29 commander, works on the Combustion Integrated Rack / Fluids & Combustion Facility (CIR FCF) in the Destiny laboratory of the International Space Station.

iss028e026402

NASA Image and Video Library

2011-08-17

ISS028-E-026402 (17 Aug. 2011) --- NASA astronaut Ron Garan, Expedition 28 flight engineer, works with the Combustion Integrated Rack (CIR) Fluids and Combustion Facility (FCF) in the Destiny laboratory of the International Space Station.

iss028e026400

NASA Image and Video Library

2011-08-17

ISS028-E-026400 (17 Aug. 2011) --- NASA astronaut Ron Garan, Expedition 28 flight engineer, works with the Combustion Integrated Rack (CIR) Fluids and Combustion Facility (FCF) in the Destiny laboratory of the International Space Station.

FIR

NASA Image and Video Library

2013-09-16

ISS037-E-001115 (16 Sept. 2013) ---NASA astronaut Karen Nyberg, Expedition 37 flight engineer, works with test samples housed in the Light Microscopy Module (LMM) inside the Fluids Integrated Rack of the International Space Station’s Destiny laboratory.

Kelly with CIR

NASA Image and Video Library

2010-10-26

ISS025-E-009308 (26 Oct. 2010) --- NASA astronaut Scott Kelly, Expedition 25 flight engineer, works on the Combustion Integrated Rack (CIR) Multi-user Drop Combustion Apparatus (MDCA) in the Destiny laboratory of the International Space Station. Kelly set up an experiment run on the Fluids & Combustion Facility (FCF) with a new fuel reservoir, ground-assisted by Payload Operations Integration Center/Huntsville (POIC).

International Space Station -- Combustion Rack

NASA Technical Reports Server (NTRS)

2000-01-01

The combustion chamber for the Combustion Integrated Rack section of the Fluids and Combustion Facility (FCF) is shown extracted for servicing. The FCF will be installed, in phases, in the Destiny, the U.S. Laboratory Module of the International Space Station (ISS), and will accommodate multiple users for a range of investigations. This is an engineering mockup; the flight hardware is subject to change as designs are refined. The FCF is being developed by the Microgravity Science Division (MSD) at the NASA Glenn Research Center. (Photo credit: NASA/Marshall Space Flight Center)

International Space Station - Combustion Rack

NASA Technical Reports Server (NTRS)

2000-01-01

The combustion chamber for the Combustion Integrated Rack section of the Fluids and Combustion Facility (FCF) is shown opened for installation of burn specimens. The FCF will be installed, in phases, in the Destiny, the U.S. Laboratory Module of the International Space Station (ISS), and will accommodate multiple users for a range of investigations. This is an engineering mockup; the flight hardware is subject to change as designs are refined. The FCF is being developed by the Microgravity Science Division (MSD) at the NASA Glenn Research Center. (Photo credit: NASA/Marshall Space Flight Center)

International Space Station -- Combustion Rack

NASA Technical Reports Server (NTRS)

2000-01-01

The combustion chamber for the Combustion Integrated Rack section of the Fluids and Combustion Facility (FCF) is shown in its operational configuration. The FCF will be installed, in phases, in the Destiny, the U.S. Laboratory Module of the International Space Station (ISS), and will accommodate multiple users for a range of investigations. This is an engineering mockup; the flight hardware is subject to change as designs are refined. The FCF is being developed by the Microgravity Science Division (MSD) at the NASA Glenn Research Center. (Photo credit: NASA/Marshall Space Flight Center)

Nespoli works with the LMM Spindle Bracket Assembly in the FIR

NASA Image and Video Library

2011-03-01

ISS026-E-031090 (1 March 2011) --- European Space Agency astronaut Paolo Nespoli, Expedition 26 flight engineer, works with the Light Microscopy Module (LMM) Spindle Bracket Assembly in the Fluids Integrated Rack (FIR) in the Destiny laboratory of the International Space Station.

iss038e055240

NASA Image and Video Library

2014-02-24

ISS038-E-055240 (24 Feb. 2014) --- In the International Space Station's Destiny laboratory, NASA astronaut Mike Hopkins, Expedition 38 flight engineer, sets up the Advanced Colloids Experiment (ACE) housed in the Light Microscopy Module (LMM) inside the Fluids Integrated Rack. ACE studies microscopic particles suspended in a liquid.

Nespoli works with the LMM Spindle Bracket Assembly in the FIR

NASA Image and Video Library

2011-03-01

ISS026-E-031086 (1 March 2011) --- European Space Agency astronaut Paolo Nespoli, Expedition 26 flight engineer, works with the Light Microscopy Module (LMM) Spindle Bracket Assembly in the Fluids Integrated Rack (FIR) in the Destiny laboratory of the International Space Station.

Nespoli works with the LMM Spindle Bracket Assembly in the FIR

NASA Image and Video Library

2011-03-01

ISS026-E-031084 (1 March 2011) --- European Space Agency astronaut Paolo Nespoli, Expedition 26 flight engineer, works with the Light Microscopy Module (LMM) Spindle Bracket Assembly in the Fluids Integrated Rack (FIR) in the Destiny laboratory of the International Space Station.

Combustion, Complex Fluids, and Fluid Physics Experiments on the ISS

NASA Technical Reports Server (NTRS)

Motil, Brian; Urban, David

2012-01-01

From the very early days of human spaceflight, NASA has been conducting experiments in space to understand the effect of weightlessness on physical and chemically reacting systems. NASA Glenn Research Center (GRC) in Cleveland, Ohio has been at the forefront of this research looking at both fundamental studies in microgravity as well as experiments targeted at reducing the risks to long duration human missions to the moon, Mars, and beyond. In the current International Space Station (ISS) era, we now have an orbiting laboratory that provides the highly desired condition of long-duration microgravity. This allows continuous and interactive research similar to Earth-based laboratories. Because of these capabilities, the ISS is an indispensible laboratory for low gravity research. NASA GRC has been actively involved in developing and operating facilities and experiments on the ISS since the beginning of a permanent human presence on November 2, 2000. As the lead Center for combustion, complex fluids, and fluid physics; GRC has led the successful implementation of the Combustion Integrated Rack (CIR) and the Fluids Integrated Rack (FIR) as well as the continued use of other facilities on the ISS. These facilities have supported combustion experiments in fundamental droplet combustion; fire detection; fire extinguishment; soot phenomena; flame liftoff and stability; and material flammability. The fluids experiments have studied capillary flow; magneto-rheological fluids; colloidal systems; extensional rheology; pool and nucleate boiling phenomena. In this paper, we provide an overview of the experiments conducted on the ISS over the past 12 years.

Light Microscopy Module Imaging Tested and Demonstrated

NASA Technical Reports Server (NTRS)

Gati, Frank

2004-01-01

The Fluids Integrated Rack (FIR), a facility-class payload, and the Light Microscopy Module (LMM), a subrack payload, are integrated research facilities that will fly in the U.S. Laboratory module, Destiny, aboard the International Space Station. Both facilities are being engineered, designed, and developed at the NASA Glenn Research Center by Northrop Grumman Information Technology. The FIR is a modular, multiuser scientific research facility that is one of two racks that make up the Fluids and Combustion Facility (the other being the Combustion Integrated Rack). The FIR has a large volume dedicated for experimental hardware; easily reconfigurable diagnostics, power, and data systems that allow for unique experiment configurations; and customizable software. The FIR will also provide imagers, light sources, power management and control, command and data handling for facility and experiment hardware, and data processing and storage. The first payload in the FIR will be the LMM. The LMM integrated with the FIR is a remotely controllable, automated, on-orbit microscope subrack facility, with key diagnostic capabilities for meeting science requirements--including video microscopy to observe microscopic phenonema and dynamic interactions, interferometry to make thin-film measurements with nanometer resolution, laser tweezers to manipulate micrometer-sized particles, confocal microscopy to provide enhanced three-dimensional visualization of structures, and spectrophotometry to measure the photonic properties of materials. Vibration disturbances were identified early in the LMM development phase as a high risk for contaminating the science microgravity environment. An integrated FIR-LMM test was conducted in Glenn's Acoustics Test Laboratory to assess mechanical sources of vibration and their impact to microscopic imaging. The primary purpose of the test was to characterize the LMM response at the sample location, the x-y stage within the microscope, to vibration emissions from the FIR and LMM support structures.

International Space Station -- Combustion Rack

NASA Technical Reports Server (NTRS)

2000-01-01

The combustion chamber for the Combustion Integrated Rack section of the Fluids and Combustion Facility (FCF) is shown extracted for servicing and with the optical bench rotated 90 degrees for access to the rear elements. The FCF will be installed, in phases, in the Destiny, the U.S. Laboratory Module of the International Space Station (ISS), and will accommodate multiple users for a range of investigations. This is an engineering mockup; the flight hardware is subject to change as designs are refined. The FCF is being developed by the Microgravity Science Division (MSD) at the NASA Glenn Research Center. (Photo credit: NASA/Marshall Space Flight Center)

FIR Light Microscopy Module Set Up

NASA Image and Video Library

2009-11-09

ISS021-E-022460 (9 Nov. 2009) --- Canadian Space Agency astronaut Robert Thirsk, Expedition 21 flight engineer, installs the Light Microscopy Module (LMM) Spindle Bracket Assembly in the Fluids Integrated Rack (FIR) in the Destiny laboratory of the International Space Station. NASA astronaut Nicole Stott (out of frame), flight engineer, assisted Thirsk.

FIR Light Microscopy Module Set Up

NASA Image and Video Library

2009-11-09

ISS021-E-022459 (9 Nov. 2009) --- NASA astronaut Nicole Stott, Expedition 21 flight engineer, installs the Light Microscopy Module (LMM) Spindle Bracket Assembly in the Fluids Integrated Rack (FIR) in the Destiny laboratory of the International Space Station. Canadian Space Agency astronaut Robert Thirsk (out of frame) assisted Stott.

FE Garan servicing the FCF in the US Lab

NASA Image and Video Library

2011-05-26

ISS028-E-005602 (26 May 2011) --- NASA astronaut Ron Garan, Expedition 28 flight engineer, services the Fluids Combustion Facility in the Fluids Integrated Rack on the Destiny lab aboard the International Space Station by changing out the Bio sample on the Bio Base. Garan and two Russian cosmonaut crewmates for Expedition 28 will be joined by three more crew members on the station in about one and a half weeks.

Burbank conducts PACE Session

NASA Image and Video Library

2011-12-01

ISS030-E-007417 (1 Dec. 2011) --- In the International Space Station?s Destiny laboratory, NASA astronaut Dan Burbank, Expedition 30 commander, conducts a session with the Preliminary Advanced Colloids Experiment (PACE) at the Light Microscopy Module (LMM) in the Fluids Integrated Rack / Fluids Combustion Facility (FIR/FCF). PACE is designed to investigate the capability of conducting high magnification colloid experiments with the LMM for determining the minimum size particles which can be resolved with it.

Burbank conducts PACE Session

NASA Image and Video Library

2011-12-01

ISS030-E-007418 (1 Dec. 2011) --- In the International Space Station’s Destiny laboratory, NASA astronaut Dan Burbank, Expedition 30 commander, conducts a session with the Preliminary Advanced Colloids Experiment (PACE) at the Light Microscopy Module (LMM) in the Fluids Integrated Rack / Fluids Combustion Facility (FIR/FCF). PACE is designed to investigate the capability of conducting high magnification colloid experiments with the LMM for determining the minimum size particles which can be resolved with it.

Burbank conducts PACE Session

NASA Image and Video Library

2011-12-01

ISS030-E-007419 (1 Dec. 2011) --- In the International Space Station’s Destiny laboratory, NASA astronaut Dan Burbank, Expedition 30 commander, conducts a session with the Preliminary Advanced Colloids Experiment (PACE) at the Light Microscopy Module (LMM) in the Fluids Integrated Rack / Fluids Combustion Facility (FIR/FCF). PACE is designed to investigate the capability of conducting high magnification colloid experiments with the LMM for determining the minimum size particles which can be resolved with it.

ACE-1 experiment

NASA Image and Video Library

2013-06-24

In the International Space Stations Destiny laboratory,NASA astronaut Karen Nyberg,Expedition 36 flight engineer,speaks into a microphone while conducting a session with the Advanced Colloids Experiment (ACE)-1 sample preparation at the Light Microscopy Module (LMM) in the Fluids Integrated Rack / Fluids Combustion Facility (FIR/FCF). ACE-1 is a series of microscopic imaging investigations that uses the microgravity environment to examine flow characteristics and the evolution and ordering effects within a group of colloidal materials.

The NASA Microgravity Fluid Physics Program: Knowledge for Use on Earth and Future Space Missions

NASA Technical Reports Server (NTRS)

Kohl, Fred J.; Singh, Bhim S.; Alexander, J. Iwan; Shaw, Nancy J.; Hill, Myron E.; Gati, Frank G.

2002-01-01

Building on over four decades of research and technology development related to the behavior of fluids in low gravity environments, the current NASA Microgravity Fluid Physics Program continues the quest for knowledge to further understand and design better fluids systems for use on earth and in space. The purpose of the Fluid Physics Program is to support the goals of NASA's Biological and Physical Research Enterprise which seeks to exploit the space environment to conduct research and to develop commercial opportunities, while building the vital knowledge base needed to enable efficient and effective systems for protecting and sustaining humans during extended space flights. There are currently five major research areas in the Microgravity Fluid Physics Program: complex fluids, multiphase flows and phase change, interfacial phenomena, biofluid mechanics, and dynamics and instabilities. Numerous investigations into these areas are being conducted in both ground-based laboratories and facilities and in the flight experiments program. Most of the future NASA-sponsored fluid physics and transport phenomena studies will be carried out on the International Space Station in the Fluids Integrated Rack, in the Microgravity Science Glovebox, in EXPRESS racks, and in other facilities provided by international partners. This paper will present an overview of the near- and long-term visions for NASA's Microgravity Fluid Physics Research Program and brief descriptions of hardware systems planned to achieve this research.

FIR Light Microscopy Module Set Up

NASA Image and Video Library

2009-11-09

ISS021-E-022457 (9 Nov. 2009) --- NASA astronaut Nicole Stott, Expedition 21 flight engineer, uses a communication system while installing the Light Microscopy Module (LMM) Spindle Bracket Assembly in the Fluids Integrated Rack (FIR) in the Destiny laboratory of the International Space Station. Canadian Space Agency astronaut Robert Thirsk (out of frame) assisted Stott.

The NASA Microgravity Fluid Physics Program: Research Plans for the ISS

NASA Technical Reports Server (NTRS)

Kohl, Fred J.; Singh, Bhim S.; Shaw, Nancy J.; Chiaramonte, Francis P.

2003-01-01

Building on over four decades of research and technology development related to the behavior of fluids in low gravity environments, the current NASA Microgravity Fluid Physics Program continues the quest for knowledge to further understand and design better fluids systems for use on earth and in space. NASA's Biological and Physical Research Enterprise seeks to exploit the space environment to conduct research supporting human exploration of space (strategic research), research of intrinsic scientific importance and impact (fundamental research), and commercial research. The strategic research thrust will build the vital knowledge base needed to enable NASA's mission to explore the Universe and search for life. There are currently five major research areas in the Microgravity Fluid Physics Program: complex fluids, niultiphase flows and phase change, interfacial phenomena, biofluid mechanics, and dynamics and instabilities. Numerous investigations into these areas are being conducted in both ground-based laboratories and facilities and in the flight experiments program. Most of the future NASA- sponsored flight experiments in microgravity fluid physics and transport phenomena will be carried out on the International Space Station (ISS) in the Fluids Integrated Rack (FIR), in the Microgravity Science Glovebox (MSG), in EXPRESS racks, and in other facilities provided by international partners. This paper presents an overview of the near- and long-term visions for NASA's Microgravity Fluid Physics Research Program and brief descriptions of hardware systems planned to enable this research.

ACE-1 experiment

NASA Image and Video Library

2013-06-24

ISS036-E-019760 (24 June 2013) --- In the International Space Station’s Destiny laboratory, NASA astronaut Karen Nyberg, Expedition 36 flight engineer, conducts a session with the Advanced Colloids Experiment (ACE)-1 sample preparation at the Light Microscopy Module (LMM) in the Fluids Integrated Rack / Fluids Combustion Facility (FIR/FCF). ACE-1 is a series of microscopic imaging investigations that uses the microgravity environment to examine flow characteristics and the evolution and ordering effects within a group of colloidal materials.

Microgravity

NASA Image and Video Library

2000-01-31

The optical bench for the Fluid Integrated Rack section of the Fluids and Combustion Facility (FCF) is shown in its operational configuration. The FCF will be installed, in phases, in the Destiny, the U.S. Laboratory Module of the International Space Station (ISS), and will accommodate multiple users for a range of investigations. This is an engineering mockup; the flight hardware is subject to change as designs are refined. The FCF is being developed by the Microgravity Science Division (MSD) at the NASA Glenn Research Center. (Photo credit: NASA/Marshall Space Flight Center)

Microgravity

NASA Image and Video Library

2000-01-31

The optical bench for the Fluids Integrated Rack section of the Fluids and Combustion Facility (FCF) is shown extracted for servicing. The FCF will be installed, in phases, in the Destiny, the U.S. Laboratory Module of the International Space Station (ISS), and will accommodate multiple users for a range of investigations. This is an engineering mockup; the flight hardware is subject to change as designs are refined. The FCF is being developed by the Microgravity Science Division (MSD) at the NASA Glenn Research Center. (Photo credit: NASA/Marshall Space Flight Center)

ACE-1 experiment

NASA Image and Video Library

2013-06-24

ISS036-E-019830 (24 June 2013) --- In the International Space Station’s Destiny laboratory, NASA astronaut Karen Nyberg, Expedition 36 flight engineer, speaks into a microphone while conducting a session with the Advanced Colloids Experiment (ACE)-1 sample preparation at the Light Microscopy Module (LMM) in the Fluids Integrated Rack / Fluids Combustion Facility (FIR/FCF). ACE-1 is a series of microscopic imaging investigations that uses the microgravity environment to examine flow characteristics and the evolution and ordering effects within a group of colloidal materials.

Advanced Plant Experiment, APEX-4

NASA Image and Video Library

2017-03-10

Advanced Plant Experiment, APEX-4, support in the Telescience Support Center at NASA Glenn. APEX-4 continues a highly successful investigation into the effects of microgravity on the development of roots and cells on plant seedlings. After four days of growth, the petri plate will be inserted into the Fluids Integrated Rack (FIR) Light Microscopy Module (LMM) facility for detailed imaging.

International Standard Payload Rack volume

NASA Technical Reports Server (NTRS)

2001-01-01

Outer dimensions of the International Standard Payload Rack (ISPR) that will be used on the International Space Station (ISS) sets the envelope for scientists designing hardware for experiments in biological and physical sciences aboard ISS. The ISPR includes attachments to ISS utilities (electrical power, heating and cooling, data, fluids, vacuum, etc.) through standoffs that hold the racks in place in the lab modules. Usage will range from facilities that take entire racks to specialized drawers occupying a portion of a rack.

Conceptual design of two-phase fluid mechanics and heat transfer facility for spacelab

NASA Technical Reports Server (NTRS)

North, B. F.; Hill, M. E.

1980-01-01

Five specific experiments were analyzed to provide definition of experiments designed to evaluate two phase fluid behavior in low gravity. The conceptual design represents a fluid mechanics and heat transfer facility for a double rack in Spacelab. The five experiments are two phase flow patterns and pressure drop, flow boiling, liquid reorientation, and interface bubble dynamics. Hardware was sized, instrumentation and data recording requirements defined, and the five experiments were installed as an integrated experimental package. Applicable available hardware was selected in the experiment design and total experiment program costs were defined.

Gravity-Dependent Combustion and Fluids Research - From Drop Towers to Aircraft to the ISS

NASA Technical Reports Server (NTRS)

Urban, David L.; Singh, Bhim S.; Kohl, Fred J.

2007-01-01

Driven by the need for knowledge related to the low-gravity environment behavior of fluids in liquid fuels management, thermal control systems and fire safety for spacecraft, NASA embarked on a decades long research program to understand, accommodate and utilize the relevant phenomena. Beginning in the 1950s, and continuing through to today, drop towers and aircraft were used to conduct an ever broadening and increasingly sophisticated suite of experiments designed to elucidate the underlying gravity-dependent physics that drive these processes. But the drop towers and aircraft afford only short time periods of continuous low gravity. Some of the earliest rocket test flights and manned space missions hosted longer duration experiments. The relatively longer duration low-g times available on the space shuttle during the 1980s and 1990s enabled many specialized experiments that provided unique data for a wide range of science and engineering disciplines. Indeed, a number of STS-based Spacelab missions were dedicated solely to basic and applied microgravity research in the biological, life and physical sciences. Between 1980 and 2000, NASA implemented a vigorous Microgravity Science Program wherein combustion science and fluid physics were major components. The current era of space stations from the MIR to the International Space Station have opened up a broad range of opportunities and facilities that are now available to support both applied research for technologies that will help to enable the future exploration missions and for a continuation of the non-exploration basic research that began over fifty years ago. The ISS-based facilities of particular value to the fluid physics and combustion/fire safety communities are the Fluids and Combustion Facility Combustion Integrated Rack and the Fluids Integrated Rack.

Design and Testing of a Breadboard Electrical Power Control Unit for the Fluid Combustion Facility Experiment

NASA Technical Reports Server (NTRS)

Kimnach, Greg L.; Lebron, Ramon C.

1999-01-01

The Fluid Combustion Facility (FCF) Project and the Power Technology Division at the NASA Glenn Research Center (GRC) at Lewis Field in Cleveland, OH along with the Sundstrand Corporation in Rockford, IL are jointly developing an Electrical Power Converter Unit (EPCU) for the Fluid Combustion Facility to be flown on the International Space Station (ISS). The FCF facility experiment contains three racks: A core rack, a combustion rack, and a fluids rack. The EPCU will be used as the power interface to the ISS 120V(sub dc) power distribution system by each FCF experiment rack which requires 28V(sub dc). The EPCU is a modular design which contains three 120V(sub dc)-to-28V(sub dc) full-bridge, power converters rated at 1 kW(sub e) each bus transferring input relays and solid-state, current-limiting input switches, 48 current-limiting, solid-state, output switches; and control and telemetry hardware. The EPCU has all controls required to autonomously share load demand between the power feeds and--if absolutely necessary--shed loads. The EPCU, which maximizes the usage of allocated ISS power and minimizes loss of power to loads, can be paralleled with other EPCUs. This paper overviews the electrical design and operating characteristics of the EPCU and presents test data from the breadboard design.

ACE-1 experiment

NASA Image and Video Library

2013-06-24

ISS036-E-019783 (24 June 2013) --- In the International Space Station’s Destiny laboratory, a fisheye lens attached to an electronic still camera was used to capture this image of NASA astronaut Karen Nyberg, Expedition 36 flight engineer, as she conducts a session with the Advanced Colloids Experiment (ACE)-1 sample preparation at the Light Microscopy Module (LMM) in the Fluids Integrated Rack / Fluids Combustion Facility (FIR/FCF). ACE-1 is a series of microscopic imaging investigations that uses the microgravity environment to examine flow characteristics and the evolution and ordering effects within a group of colloidal materials.

KSC-01pp1425

NASA Image and Video Library

2001-08-06

KENNEDY SPACE CENTER, Fla. -- On Launch Pad 39A, Discovery’s payload bay doors close on the payloads inside. On the Integrated Cargo Carrier seen here is the Early Ammonia Servicer (EAS) on the left. The EAS contains spare ammonia for the Station’s cooling system. Ammonia is the fluid used in the radiators that cool the Station’s electronics. The EAS will be installed on the P6 truss holding the giant U.S. solar arrays, batteries and cooling radiators. Other payloads in the bay are the Multi-Purpose Logistics Module Leonardo, filled with laboratory racks of science equipment and racks and platforms of experiments and supplies, and various experiments attached on the port and starboard adapter beams. Discovery is scheduled to be launched Aug. 9, 2001

Combustion, Complex Fluids, and Fluid Physics Experiments on the ISS

NASA Technical Reports Server (NTRS)

Motil, Brian; Urban, David

2012-01-01

From the very first days of human spaceflight, NASA has been conducting experiments in space to understand the effect of weightlessness on physical and chemically reacting systems. NASA Glenn Research Center (GRC) in Cleveland, Ohio has been at the forefront of this research looking at both fundamental studies in microgravity as well as experiments targeted at reducing the risks to long duration human missions to the moon, Mars, and beyond. In the current International Space Station (ISS) era, we now have an orbiting laboratory that provides the highly desired condition of long-duration microgravity. This allows continuous and interactive research similar to Earth-based laboratories. Because of these capabilities, the ISS is an indispensible laboratory for low gravity research. NASA GRC has been actively involved in developing and operating facilities and experiments on the ISS since the beginning of a permanent human presence on November 2, 2000. As the lead Center both Combustion, Fluid Physics, and Acceleration Measurement GRC has led the successful implementation of an Acceleration Measurement systems, the Combustion Integrated Rack (CIR), the Fluids Integrated Rack (FIR) as well as the continued use of other facilities on the ISS. These facilities have supported combustion experiments in fundamental droplet combustion fire detection fire extinguishment soot phenomena flame liftoff and stability and material flammability. The fluids experiments have studied capillary flow magneto-rheological fluids colloidal systems extensional rheology pool and nucleate boiling phenomena. In this paper, we provide an overview of the experiments conducted on the ISS over the past 12 years. We also provide a look to the future development. Experiments presented in combustion include areas such as droplet combustion, gaseous diffusion flames, solid fuels, premixed flame studies, fire safety, and super critical oxidation processes. In fluid physics, experiments are discussed in multiphase flows, capillary phenomena, and heat pipes. Finally in complex fluids, experiments in rheology and soft condensed materials will be presented.

Conducting Research on the International Space Station Using the EXPRESS Rack Facilities

NASA Technical Reports Server (NTRS)

Thompson, Sean W.; Lake, Robert E.

2013-01-01

Eight "Expedite the Processing of Experiments to Space Station" (EXPRESS) Rack facilities are located within the International Space Station (ISS) laboratories to provide standard resources and interfaces for the simultaneous and independent operation of multiple experiments within each rack. Each EXPRESS Rack provides eight Middeck Locker Equivalent locations and two drawer locations for powered experiment equipment, also referred to as sub-rack payloads. Payload developers may provide their own structure to occupy the equivalent volume of one, two, or four lockers as a single unit. Resources provided for each location include power (28 Vdc, 0-500 W), command and data handling (Ethernet, RS-422, 5 Vdc discrete, +/- 5 Vdc analog), video (NTSC/RS 170A), and air cooling (0-200 W). Each rack also provides water cooling (500 W) for two locations, one vacuum exhaust interface, and one gaseous nitrogen interface. Standard interfacing cables and hoses are provided on-orbit. One laptop computer is provided with each rack to control the rack and to accommodate payload application software. Four of the racks are equipped with the Active Rack Isolation System to reduce vibration between the ISS and the rack. EXPRESS Racks are operated by the Payload Operations Integration Center at Marshall Space Flight Center and the sub-rack experiments are operated remotely by the investigating organization. Payload Integration Managers serve as a focal to assist organizations developing payloads for an EXPRESS Rack. NASA provides EXPRESS Rack simulator software for payload developers to checkout payload command and data handling at the development site before integrating the payload with the EXPRESS Functional Checkout Unit for an end-to-end test before flight. EXPRESS Racks began supporting investigations onboard ISS on April 24, 2001 and will continue through the life of the ISS.

Conducting Research on the International Space Station using the EXPRESS Rack Facilities

NASA Technical Reports Server (NTRS)

Thompson, Sean W.; Lake, Robert E.

2016-01-01

Eight "Expedite the Processing of Experiments to Space Station" (EXPRESS) Rack facilities are located within the International Space Station (ISS) laboratories to provide standard resources and interfaces for the simultaneous and independent operation of multiple experiments within each rack. Each EXPRESS Rack provides eight Middeck Locker Equivalent locations and two drawer locations for powered experiment equipment, also referred to as sub-rack payloads. Payload developers may provide their own structure to occupy the equivalent volume of one, two, or four lockers as a single unit. Resources provided for each location include power (28 Vdc, 0-500 W), command and data handling (Ethernet, RS-422, 5 Vdc discrete, +/- 5 Vdc analog), video (NTSC/RS 170A), and air cooling (0-200 W). Each rack also provides water cooling for two locations (500W ea.), one vacuum exhaust interface, and one gaseous nitrogen interface. Standard interfacing cables and hoses are provided on-orbit. One laptop computer is provided with each rack to control the rack and to accommodate payload application software. Four of the racks are equipped with the Active Rack Isolation System to reduce vibration between the ISS and the rack. EXPRESS Racks are operated by the Payload Operations Integration Center at Marshall Space Flight Center and the sub-rack experiments are operated remotely by the investigating organization. Payload Integration Managers serve as a focal to assist organizations developing payloads for an EXPRESS Rack. NASA provides EXPRESS Rack simulator software for payload developers to checkout payload command and data handling at the development site before integrating the payload with the EXPRESS Functional Checkout Unit for an end-to-end test before flight. EXPRESS Racks began supporting investigations onboard ISS on April 24, 2001 and will continue through the life of the ISS.

InSPACE-3 experiment

NASA Image and Video Library

2013-08-18

ISS036-E-033948 (18 Aug. 2013) --- NASA astronaut Karen Nyberg, Expedition 36 flight engineer, works with new test samples for the Advanced Colloids Experiment, or ACE, housed in the Light Microscopy Module (LMM) inside the Fluids Integrated Rack of the International Space Station?s Destiny laboratory. Results from ACE will help researchers understand how to optimize stabilizers to extend the shelf life of products like laundry detergent, paint, ketchup and even salad dressing.

Advanced Colloids Experiment-1 (ACE-1)

NASA Image and Video Library

2013-07-22

ISS036-E-023770 (22 July 2013) --- NASA astronaut Chris Cassidy, Expedition 36 flight engineer, conducts science work with the ongoing experiment Advanced Colloids Experiment-1 (ACE-1) inside the Fluids Integrated Rack. The experiment observes colloids, microscopic particles evenly dispersed throughout materials, with the potential for manufacturing improved materials and products on Earth. Cassidy is working at the Light Microscopy Module (LMM) in the Destiny laboratory of the International Space Station.

Microgravity

NASA Image and Video Library

2000-01-31

The optical bench for the Fluids Integrated Rack section of the Fluids and Combustion Facility (FCF) is shown extracted for servicing and with the optical bench rotated 90 degrees for access to the rear elements. The FCF will be installed, in phases, in the Destiny, the U.S. Laboratory Module of the International Space Station (ISS), and will accommodate multiple users for a range of investigations. This is an engineering mockup; the flight hardware is subject to change as designs are refined. The FCF is being developed by the Microgravity Science Division (MSD) at the NASA Glenn Research Center. (Photo credit: NASA/Marshall Space Flight Center)

Microgravity

NASA Image and Video Library

2000-01-31

The optical bench for the Fluids Integrated Rack section of the Fluids and Combustion Facility (FCF) is shown extracted for servicing and with the optical bench rotated 90 degrees to access the rear elements. The FCF will be installed, in phases, in the Destiny, the U.S. Laboratory Module of the International Space Station (ISS), and will accommodate multiple users for a range of investigations. This is an engineering mockup; the flight hardware is subject to change as designs are refined. The FCF is being developed by the Microgravity Science Division (MSD) at the NASA Glenn Research Center. (Photo credit: NASA/Marshall Space Flight Center)

KSC-01pp1423

NASA Image and Video Library

2001-08-06

KENNEDY SPACE CENTER, Fla. -- On Launch Pad 39A, workers check out the loading of the payloads into Discovery’s payload bay. In the center is the Multi-Purpose Logistics Module Leonardo, filled with laboratory racks of science equipment and racks and platforms of experiments and supplies. Above Leonardo is the Integrated Cargo Carrier with the Early Ammonia Servicer (EAS) in the center. The EAS contains spare ammonia for the Station’s cooling system. Ammonia is the fluid used in the radiators that cool the Station’s electronics. The EAS will be installed on the P6 truss holding the giant U.S. solar arrays, batteries and cooling radiators. Seen below the MPLM and attached on the port and starboard adapter beams are experiments. Discovery is scheduled to be launched Aug. 9, 2001

Conducting Research on the International Space Station Using the EXPRESS Rack Facilities

NASA Technical Reports Server (NTRS)

Thompson, Sean W.; Lake, Robert E.

2014-01-01

EXPRESS Racks provide capability for payload access to ISS resources. The successful on-orbit operations and versatility of the EXPRESS Rack has facilitated the operations of many scientific areas, with the promise of continued payload support for years to come. EXPRESS Racks are currently deployed in the US Lab, Columbus and JEM. Process improvements and enhancements continue to improve the accommodations and make the integration and operations process more efficient. Payload Integration Managers serve as the primary interface between the ISS Program and EXPRESS Payload Developers. EXPRESS Project coordinates across multiple functional areas and organizations to ensure integrated EXPRESS Rack and subrack products and hardware are complete, accurate, on time, safe, and certified for flight. NASA is planning to expand the EXPRESS payload capacity by developing new Basic Express Racks expected to be on ISS in 2018.

Conducting Research on the International Space Station Using the EXPRESS Rack Facilities

NASA Technical Reports Server (NTRS)

Thompson, Sean W.; Lake, Robert E.

2013-01-01

Conducting Research on the International Space Station using the EXPRESS Rack Facilities. Sean W. Thompson and Robert E. Lake. NASA Marshall Space Flight Center, Huntsville, AL, USA. Eight "Expedite the Processing of Experiments to Space Station" (EXPRESS) Rack facilities are located within the International Space Station (ISS) laboratories to provide standard resources and interfaces for the simultaneous and independent operation of multiple experiments within each rack. Each EXPRESS Rack provides eight Middeck Locker Equivalent locations and two drawer locations for powered experiment equipment, also referred to as sub-rack payloads. Payload developers may provide their own structure to occupy the equivalent volume of one, two, or four lockers as a single unit. Resources provided for each location include power (28 Vdc, 0-500 W), command and data handling (Ethernet, RS-422, 5 Vdc discrete, +/- 5 Vdc analog), video (NTSC/RS 170A), and air cooling (0-200 W). Each rack also provides water cooling (500 W) for two locations, one vacuum exhaust interface, and one gaseous nitrogen interface. Standard interfacing cables and hoses are provided on-orbit. One laptop computer is provided with each rack to control the rack and to accommodate payload application software. Four of the racks are equipped with the Active Rack Isolation System to reduce vibration between the ISS and the rack. EXPRESS Racks are operated by the Payload Operations Integration Center at Marshall Space Flight Center and the sub-rack experiments are operated remotely by the investigating organization. Payload Integration Managers serve as a focal to assist organizations developing payloads for an EXPRESS Rack. NASA provides EXPRESS Rack simulator software for payload developers to checkout payload command and data handling at the development site before integrating the payload with the EXPRESS Functional Checkout Unit for an end-to-end test before flight. EXPRESS Racks began supporting investigations onboard ISS on April 24, 2001 and will continue through the life of the ISS.

The ISS EXPRESS Rack: An Innovative Approach of Rapid Integration

NASA Technical Reports Server (NTRS)

Sledd, Annette M.

2000-01-01

The EXpedite the PRocessing of Experiments to Space Station or EXPRESS Rack System, was developed to provide Space Station accommodations for small, subrack payloads. The EXPRESS Rack accepts Space Shuttle middeck locker type payloads and International Subrack Interface Standard (ISIS) Drawer payloads, allowing previously flown payloads an opportunity to transition to the International Space Station. The EXPRESS Rack provides power, data, command and control, video, water cooling, air cooling, vacuum exhaust, and Nitrogen supply to payloads. The EXPRESS Rack system also includes transportation racks to transport payloads to and from the Space Station, Suitcase Simulators to allow a payload developer to verify power and data interfaces at the development site, Functional Checkout Units to allow Payload checkout at KSC prior to launch, and trainer racks for the astronauts to learn how to operate the EXPRESS Racks prior to flight. Standard hardware and software interfaces provided by the EXPRESS Rack simplify the analytical and physical integration processes, and facilitates simpler ISS payload development. The EXPRESS Rack has also formed the basis for the U.S. Life Sciences payload racks and the Window Observational Research Facility on Space Station.

Microscope-Based Fluid Physics Experiments in the Fluids and Combustion Facility on ISS

NASA Technical Reports Server (NTRS)

Doherty, Michael P.; Motil, Susan M.; Snead, John H.; Malarik, Diane C.

2000-01-01

At the NASA Glenn Research Center, the Microgravity Science Program is planning to conduct a large number of experiments on the International Space Station in both the Fluid Physics and Combustion Science disciplines, and is developing flight experiment hardware for use within the International Space Station's Fluids and Combustion Facility. Four fluids physics experiments that require an optical microscope will be sequentially conducted within a subrack payload to the Fluids Integrated Rack of the Fluids and Combustion Facility called the Light Microscopy Module, which will provide the containment, changeout, and diagnostic capabilities to perform the experiments. The Light Microscopy Module is planned as a fully remotely controllable on-orbit microscope facility, allowing flexible scheduling and control of experiments within International Space Station resources. This paper will focus on the four microscope-based experiments, specifically, their objectives and the sample cell and instrument hardware to accommodate their requirements.

STS-55 German Payload Specialist Walter at the SL-D2 Fluid Physics Module

NASA Technical Reports Server (NTRS)

1993-01-01

STS-55 German Payload Specialist 1 Ulrich Walter conducts an experiment using the advanced fluid physics module located in Spacelab Deutsche 2 (SL-D2) Rack 8 Werkstofflabor (WL) (Material Sciences Laboratory) aboard Earth-orbiting Columbia, Orbiter Vehicle (OV) 102. Walter uses intravehicular activity (IVA) foot restraints to position himself in front of the rack. Walter represents the German Aerospace Research Establishment (DLR) on the 10-day mission.

Nyberg working with ACE in U.S. Laboratory

NASA Image and Video Library

2013-08-18

ISS036-E-035770 (18 Aug. 2013) --- NASA astronaut Karen Nyberg, Expedition 36 flight engineer, works with new test samples for the Advanced Colloids Experiment, or ACE, housed in the Light Microscopy Module (LMM) inside the Fluids Integrated Rack of the International Space Station?s Destiny laboratory. Results from ACE will help researchers understand how to optimize stabilizers to extend the shelf life of products like laundry detergent, paint, ketchup and even salad dressing.

Nyberg working with ACE in U.S. Laboratory

NASA Image and Video Library

2013-08-18

ISS036-E-035767 (18 Aug. 2013) --- NASA astronaut Karen Nyberg, Expedition 36 flight engineer, works with new test samples for the Advanced Colloids Experiment, or ACE, housed in the Light Microscopy Module (LMM) inside the Fluids Integrated Rack of the International Space Station?s Destiny laboratory. Results from ACE will help researchers understand how to optimize stabilizers to extend the shelf life of products like laundry detergent, paint, ketchup and even salad dressing.

Nyberg working with ACE in U.S. Laboratory

NASA Image and Video Library

2013-08-18

ISS036-E-035780 (18 Aug. 2013) --- NASA astronaut Karen Nyberg, Expedition 36 flight engineer, works with new test samples for the Advanced Colloids Experiment, or ACE, housed in the Light Microscopy Module (LMM) inside the Fluids Integrated Rack of the International Space Station?s Destiny laboratory. Results from ACE will help researchers understand how to optimize stabilizers to extend the shelf life of products like laundry detergent, paint, ketchup and even salad dressing.

Ford poses at the FIR/LMM/ACE in the U.S. Laboratory

NASA Image and Video Library

2013-02-21

ISS034-E-056144 (21 Feb. 2013) --- Inside the U.S. Laboratory (Destiny) aboard the Earth-orbiting International Space Statio, NASA astronaut Kevin Ford, Expedition 34 commander, is seen with the Fluids Integration Rack (FIR)/Light Microscopy Module (LMM)/Advanced Colloids Experiment (ACE). ACE samples, which produce microscopic images of materials containing small colloidal particles, are scheduled for arrival on SpaceX-2 in the first week of March.

Information technology equipment cooling method

DOEpatents

Schultz, Mark D.

2015-10-20

According to one embodiment, a system for removing heat from a rack of information technology equipment may include a sidecar indoor air to liquid heat exchanger that cools air utilized by the rack of information technology equipment to cool the rack of information technology equipment. The system may also include a liquid to liquid heat exchanger and an outdoor heat exchanger. The system may further include configurable pathways to connect and control fluid flow through the sidecar heat exchanger, the liquid to liquid heat exchanger, the rack of information technology equipment, and the outdoor heat exchanger based upon ambient temperature and/or ambient humidity to remove heat generated by the rack of information technology equipment.

Microgravity

NASA Image and Video Library

1999-01-01

Line drawing depicts the location of one of three racks that will make up the Materials Science Research Facility in the U.S. Destiny laboratory module to be attached to the International Space Station (ISS). Other positions will be occupied by a variety of racks supporting research in combustion, fluids, biotechnology, and human physiology, and racks to support lab and station opertions. The Materials Science Research Facility is managed by NASA's Marshall Space Flight Center. Photo credit: NASA/Marshall Space Flight Center

Microgravity

NASA Image and Video Library

2000-01-30

Engineers from NASA's Glenn Research Center, demonstrate access to one of the experiment racks planned for the U.S. Destiny laboratory module on the International Space Station. This mockup has the full diameter, full corridor width, and half the length of the module. The mockup includes engineering mockups of the Fluids and Combustion Facility being developed by NASA's Glenn Research Center. (The full module will be six racks long; the mockup is three rack long) Photo credit: NASA/Marshall Space Flight Center

Directly connected heat exchanger tube section and coolant-cooled structure

DOEpatents

Chainer, Timothy J.; Coico, Patrick A.; Graybill, David P.; Iyengar, Madhusudan K.; Kamath, Vinod; Kochuparambil, Bejoy J.; Schmidt, Roger R.; Steinke, Mark E.

2015-09-15

A method is provided for fabricating a cooling apparatus for cooling an electronics rack, which includes an air-to-liquid heat exchanger, one or more coolant-cooled structures, and a tube. The heat exchanger is associated with the electronics rack and disposed to cool air passing through the rack, includes a plurality of coolant-carrying tube sections, each tube section having a coolant inlet and outlet, one of which is coupled in fluid communication with a coolant loop to facilitate flow of coolant through the tube section. The coolant-cooled structure(s) is in thermal contact with an electronic component(s) of the rack, and facilitates transfer of heat from the component(s) to the coolant. The tube connects in fluid communication one coolant-cooled structure and the other of the coolant inlet or outlet of the one tube section, and facilitates flow of coolant directly between that coolant-carrying tube section of the heat exchanger and the coolant-cooled structure.

Directly connected heat exchanger tube section and coolant-cooled structure

DOEpatents

Chainer, Timothy J; Coico, Patrick A; Graybill, David P; Iyengar, Madhusudan K; Kamath, Vinod; Kochuparambil, Bejoy J; Schmidt, Roger R; Steinke, Mark E

2014-04-01

A cooling apparatus for an electronics rack is provided which includes an air-to-liquid heat exchanger, one or more coolant-cooled structures and a tube. The heat exchanger, which is associated with the electronics rack and disposed to cool air passing through the rack, includes a plurality of distinct, coolant-carrying tube sections, each tube section having a coolant inlet and a coolant outlet, one of which is coupled in fluid communication with a coolant loop to facilitate flow of coolant through the tube section. The coolant-cooled structure(s) is in thermal contact with an electronic component(s) of the rack, and facilitates transfer of heat from the component(s) to the coolant. The tube connects in fluid communication one coolant-cooled structure and the other of the coolant inlet or outlet of the one tube section, and facilitates flow of coolant directly between that coolant-carrying tube section of the heat exchanger and the coolant-cooled structure.

Microgravity

NASA Image and Video Library

2000-01-30

Engineers from NASA's Glen Research Center demonstrate the access to one of the experiment racks plarned for the U.S. Destiny laboratory module on the International Space Station (ISS). This mockup has the full diameter, full corridor width, and half the length of the module. The mockup includes engineering mockups of the Fluids and Combustion Facility being developed by NASA's Glenn Research Center. (The full module will be six racks long; the mockup is three racks long). Photo credit: NASA/Marshall Space Flight Center (MSFC)

Updates on HRF Payloads Operations in Columbus ATCS

NASA Technical Reports Server (NTRS)

DePalo, Savino; Wright, Bruce D.; La,e Robert E.; Challis, Simon; Davenport, Robert; Pietrafesa, Donata

2011-01-01

The NASA developed Human Research Facility 1 (HRF1) and Human Research Facility (HRF2) experiment racks have been operating in the European Space Agency (ESA) Columbus module of the International Space Station (ISS) since Summer 2008. The two racks are of the same design. Since the start of operations, unexpected pressure spikes were observed in the Columbus module's thermal-hydraulic system during the racks activation sequence. The root cause of these spikes was identified in the activation command sequence in the Rack Interface Controller (RIC), which controls the flow of thermal-hydraulic system fluid through the rack. A new Common RIC Software (CRS) release fixed the bug and was uploaded on both racks in late 2009. This paper gives a short introduction to the topic, describes the Columbus module countermeasures to mitigate the spikes, describes the ground validation test of the new software, and describes the flight checks performed before and after the final upload. Finally, the new on-orbit test designed to further simplify the racks hydraulic management is presented.

Information technology equipment cooling system

DOEpatents

Schultz, Mark D.

2014-06-10

According to one embodiment, a system for removing heat from a rack of information technology equipment may include a sidecar indoor air to liquid heat exchanger that cools warm air generated by the rack of information technology equipment. The system may also include a liquid to liquid heat exchanger and an outdoor heat exchanger. The system may further include configurable pathways to connect and control fluid flow through the sidecar heat exchanger, the liquid to liquid heat exchanger, the rack of information technology equipment, and the outdoor heat exchanger based upon ambient temperature and/or ambient humidity to remove heat from the rack of information technology equipment.

Combustion Integrated Rack (CIR)

NASA Image and Video Library

2016-06-22

NASA Glenn engineer Chris Mroczka installs a gas-jet burner in a chamber within the center’s Combustion Integrated Rack. This chamber is where scientists conduct gaseous combustion experiments in a zero gravity environment.

Microgravity

NASA Image and Video Library

2000-01-31

The combustion chamber for the Combustion Integrated Rack section of the Fluids and Combustion Facility (FCF) is shown extracted for servicing. The FCF will be installed, in phases, in the Destiny, the U.S. Laboratory Module of the International Space Station (ISS), and will accommodate multiple users for a range of investigations. This is an engineering mockup; the flight hardware is subject to change as designs are refined. The FCF is being developed by the Microgravity Science Division (MSD) at the NASA Glenn Research Center. (Photo credit: NASA/Marshall Space Flight Center)

Microgravity

NASA Image and Video Library

2000-01-31

The combustion chamber for the Combustion Integrated Rack section of the Fluids and Combustion Facility (FCF) is shown in its operational configuration. The FCF will be installed, in phases, in the Destiny, the U.S. Laboratory Module of the International Space Station (ISS), and will accommodate multiple users for a range of investigations. This is an engineering mockup; the flight hardware is subject to change as designs are refined. The FCF is being developed by the Microgravity Science Division (MSD) at the NASA Glenn Research Center. (Photo credit: NASA/Marshall Space Flight Center)

Potential pressurized payloads: Fluid and thermal experiments

NASA Technical Reports Server (NTRS)

Swanson, Theodore D.

1992-01-01

Space Station Freedom (SSF) presents the opportunity to perform long term fluid and thermal experiments in a microgravity environment. This presentation provides perspective on the need for fluids/thermal experimentation in a microgravity environment, addresses previous efforts, identifies possible experiments, and discusses the capabilities of a proposed fluid physics/dynamics test facility. Numerous spacecraft systems use fluids for their operation. Thermal control, propulsion, waste management, and various operational processes are examples of such systems. However, effective ground testing is very difficult. This is because the effect of gravity induced phenomena, such as hydrostatic pressure, buoyant convection, and stratification, overcome such forces as surface tension, diffusion, electric potential, etc., which normally dominate in a microgravity environment. Hence, space experimentation is necessary to develop and validate a new fluid based technology. Two broad types of experiments may be performed on SSF: basic research and applied research. Basic research might include experiments focusing on capillary phenomena (with or without thermal and/or solutal gradients), thermal/solutal convection, phase transitions, and multiphase flow. Representative examples of applied research might include two-phase pressure drop, two-phase flow instabilities, heat transfer coefficients, fluid tank fill/drain, tank slosh dynamics, condensate removal enhancement, and void formation within thermal energy storage materials. In order to better support such fluid/thermal experiments on board SSF, OSSA has developed a conceptual design for a proposed Fluid Physics/Dynamics Facility (FP/DF). The proposed facility consists of one facility rack permanently located on SSF and one experimenter rack which is changed out as needed to support specific experiments. This approach will minimize the on-board integration/deintegration required for specific experiments. The FP/DF will have acceleration/vibration compensation, power and thermal interfaces, computer command/data collection, a video imaging system, and a portable glove box for operations. This facility will allow real-time astronaut interaction with the testing.

The Light Microscopy Module Design and Performance Demonstrations

NASA Technical Reports Server (NTRS)

Motil, Susan M.; Snead, John H.; Griffin, DeVon W.; Hovenac, Edward A.

2003-01-01

The Light Microscopy Module (LMM) is a state-of-the-art space station payload to provide investigations in the fields of fluids, condensed matter physics, and biological sciences. The LMM hardware will reside inside the Fluids Integrated Rack (FIR), a multi-user facility class payload that will provide fundamental services for the LMM and future payloads. LMM and FIR will be launched in 2005 and both will reside in the Destiny module of the International Space Station (ISS). There are five experiments to be performed within the LMM. This paper will provide a description of the initial five experiments: the supporting FIR subsystems; LMM design; capabilities and key features; and a summary of performance demonstrations.

Combustion Integrated Rack (CIR) work

NASA Image and Video Library

2014-06-09

ISS040-E-008521 (9 June 2014) --- NASA astronaut Reid Wiseman, Expedition 40 flight engineer, removes and replaces a new manifold bottle in the Combustion Integration Rack (CIR) in the Destiny laboratory of the International Space Station.

UAH/NASA Workshop on Fluids Experiment System

NASA Technical Reports Server (NTRS)

Hendricks, J. (Editor); Askins, B. (Editor)

1979-01-01

The Fluids Experiment System is being developed to fit into a Spacelab rack. Papers presented at this workshop describe a variety of fluid and chemical experiments that would be of great benefit to researchers of processes in a low gravity environment.

Crew Member Interface with Space Station Furnace Facility

NASA Technical Reports Server (NTRS)

Cash, Martha B.

1997-01-01

The Space Station Furnace Facility (SSFF) is a facility located in the International Space Station United States Laboratory (ISS US Lab) for materials research in the microgravity environment. The SSFF will accommodate basic research, commercial applications, and studies of phenomena of metals and alloys, electronic and photonic materials, and glasses and ceramics. To support this broad base of research requirements, the SSFF will operate, regulate, and support a variety of Experiment Modules (EMs). To meet station requirements concerning the microgravity level needed for experiments, station is providing an active vibration isolation system, and SSFF provides the interface. SSFF physically consists of a Core Rack and two instrument racks (IRs) that occupy three adjacent ISS US Lab rack locations within the International Space Station (ISS). All SSFF racks are modified International Standard Payload Racks (ISPR). SSFF racks will have a 50% larger pass through area on the lower sides than ISPRs to accommodate the many rack to rack interconnections. The Instrument Racks are further modified with lowered floors and an additional removable panel (15" x 22") on top of the rack for access if needed. The Core Rack shall contain all centralized Core subsystems and ISS subsystem equipment. The two Instrument Racks shall contain the distributed Core subsystem equipment, ISS subsystem equipment, and the EMs. The Core System, which includes the Core Rack, the IR structures, and subsystem components located in the IRs serves as the central control and management for the IRs and the EMs. The Core System receives the resources provided by the International Space Station (ISS) and modifies, allocates, and distributes these resources to meet the operational requirements of the furnace. The Core System is able to support a total of four EMs and can control, support, and activate/deactivate the operations of two EMs, simultaneously. The IRs can be configured to house two small EMs or one tall vertical EM, and serve as the interface between the Core and the respective EM. The Core Rack and an adjacent Instrument Rack (containing one or more furnaces) will be delivered to the ISS in one launch. This is Integrated Configuration One (ICI). The Core Rack and IRI will be passive during transport in the Mini Pressurized Logistics Module (MPLM): Any subsequent EMs to operate within IRI are installed on-orbit. The second IR (containing one or more furnaces) is delivered to ISS on a subsequent launch which will establish Integrated Configuration Two (IC2). Additional integrated configurations will be established with the replacement of EMs or Instrument Racks.

Integrated payload and mission planning, phase 3. Volume 4: Optimum utilization of Spacelab racks and pallets

NASA Technical Reports Server (NTRS)

Logston, R. G.; Budris, G. D.

1977-01-01

The methodology to optimize the utilization of Spacelab racks and pallets and to apply this methodology to the early STS Spacelab missions was developed. A review was made of Spacelab Program requirements and flow plans, generic flow plans for racks and pallets were examined, and the principal optimization criteria and methodology were established. Interactions between schedule, inventory, and key optimization factors; schedule and cost sensitivity to optional approaches; and the development of tradeoff methodology were addressed. This methodology was then applied to early spacelab missions (1980-1982). Rack and pallet requirements and duty cycles were defined, a utilization assessment was made, and several trade studies performed involving varying degrees of Level IV integration, inventory level, and shared versus dedicated Spacelab racks and pallets.

75 FR 8549 - Airworthiness Directives; Airbus Model A300 Series Airplanes, Airbus Model A300 B4-600 Series...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-25

... rack 101VU by accomplishment of Airbus Service Bulletin (SB) A310-53-2076 was embodied on the aeroplane... the splicing with rack 107VU fitting. This condition, if not detected and corrected, could degrade the structural integrity of the crossbeam on NLG FR15A web attachment fitting of rack 107VU. Rack 107VU contains...

Burbank works on the CIR in the U.S. Laboratory

NASA Image and Video Library

2012-04-10

ISS030-E-234735 (10 April 2012) --- NASA astronaut Dan Burbank, Expedition 30 commander, works on the Combustion Integrated Rack (CIR) in the Destiny laboratory of the International Space Station. Burbank disconnected the Moderate Temperature Loop (MTL), Vacuum Exhaust System (VES) and station nitrogen lines of the Optics Bench, translated and rotated it out of the way and replaced a Fluids and Combustion Facility / Diagnostic Control Module (FCF DCM) on its back. Afterwards, Burbank returned the Optics Bench to its nominal position and reconnected the MTL, VES and station nitrogen lines.

Microgravity

NASA Image and Video Library

2000-01-31

The combustion chamber for the Combustion Integrated Rack section of the Fluids and Combustion Facility (FCF) is shown opened for installation of burn specimens. The FCF will be installed, in phases, in the Destiny, the U.S. Laboratory Module of the International Space Station (ISS), and will accommodate multiple users for a range of investigations. This is an engineering mockup; the flight hardware is subject to change as designs are refined. The FCF is being developed by the Microgravity Science Division (MSD) at the NASA Glenn Research Center. (Photo credit: NASA/Marshall Space Flight Center)

Microgravity

NASA Image and Video Library

2000-01-30

Engineers from NASA's Glenn Research Center demonstrate the access to one of the experiment racks planned for the U.S. Destiny laboratory module on the International Space Station (ISS). This mockup has the full diameter, full corridor width, and half the length of the module. The mockup includes engineering mockups of the Fluids and Combustion Facility being developed by NASA's Glenn Research Center. (The full module will be six racks long; the mockup is three racks long). Listening at center is former astronaut Brewster Shaw (center), now a program official with the Boeing Co., the ISS prime contractor. Photo credit: NASA/Marshall Space Flight Center (MSFC)

Microgravity Science Glovebox (MSG)

NASA Technical Reports Server (NTRS)

1998-01-01

The Microgravity Science Glovebox is a facility for performing microgravity research in the areas of materials, combustion, fluids and biotechnology science. The facility occupies a full ISPR, consisting of: the ISPR rack and infrastructure for the rack, the glovebox core facility, data handling, rack stowage, outfitting equipment, and a video subsystem. MSG core facility provides the experiment developers a chamber with air filtering and recycling, up to two levels of containment, an airlock for transfer of payload equipment to/from the main volume, interface resources for the payload inside the core facility, resources inside the airlock, and storage drawers for MSG support equipment and consumables.

Microgravity

NASA Image and Video Library

1998-05-01

The Microgravity Science Glovebox is a facility for performing microgravity research in the areas of materials, combustion, fluids and biotechnology science. The facility occupies a full ISPR, consisting of: the ISPR rack and infrastructure for the rack, the glovebox core facility, data handling, rack stowage, outfitting equipment, and a video subsystem. MSG core facility provides the experiment developers a chamber with air filtering and recycling, up to two levels of containment, an airlock for transfer of payload equipment to/from the main volume, interface resources for the payload inside the core facility, resources inside the airlock, and storage drawers for MSG support equipment and consumables.

sts128-s-047

NASA Image and Video Library

2009-09-14

STS128-S-047 (11 Sept. 2009) --- Space Shuttle Discovery?s main landing gear touches down at NASA's Dryden Flight Research Center at Edwards Air Force Base in California, concluding a successful mission to the International Space Station. Onboard are NASA astronauts Rick Sturckow, commander; Kevin Ford, pilot; John ?Danny? Olivas, Patrick Forrester, Jose Hernandez and Tim Kopra, all mission specialists; along with European Space Agency astronaut Christer Fuglesang, mission specialist. Discovery landed at 5:53 p.m. (PDT) on Sept. 11, 2009 to end the STS-128 mission, completing its almost 14-day journey of more than 5.7 million miles in space. The landing was diverted to California due to marginal weather at the Kennedy Space Center. Discovery?s mission featured three spacewalks and the delivery of two refrigerator-sized science racks to the space station. One rack will be used to conduct experiments on materials such as metals, glasses and ceramics. The results from these experiments could lead to the development of better materials on Earth. The other rack will be used for fluid physics research. Understanding how fluids react in microgravity could lead to improved designs for fuel tanks, water systems and other fluid-based systems.

sts128-s-045

NASA Image and Video Library

2009-09-11

STS128-S-045 (11 Sept. 2009) --- Space Shuttle Discovery?s main landing gear touches down at NASA's Dryden Flight Research Center at Edwards Air Force Base in California, concluding a successful mission to the International Space Station. Onboard are NASA astronauts Rick Sturckow, commander; Kevin Ford, pilot; John ?Danny? Olivas, Patrick Forrester, Jose Hernandez and Tim Kopra, all mission specialists; along with European Space Agency astronaut Christer Fuglesang, mission specialist. Discovery landed at 5:53 p.m. (PDT) on Sept. 11, 2009 to end the STS-128 mission, completing its almost 14-day journey of more than 5.7 million miles in space. The landing was diverted to California due to marginal weather at the Kennedy Space Center. Discovery?s mission featured three spacewalks and the delivery of two refrigerator-sized science racks to the space station. One rack will be used to conduct experiments on materials such as metals, glasses and ceramics. The results from these experiments could lead to the development of better materials on Earth. The other rack will be used for fluid physics research. Understanding how fluids react in microgravity could lead to improved designs for fuel tanks, water systems and other fluid-based systems.

sts128-s-048

NASA Image and Video Library

2009-09-11

STS128-S-048 (11 Sept. 2009) --- With its drag chute deployed, Space Shuttle Discovery slows to a stop after landing at NASA's Dryden Flight Research Center at Edwards Air Force Base in California, concluding a successful mission to the International Space Station. Onboard are NASA astronauts Rick Sturckow, commander; Kevin Ford, pilot; John ?Danny? Olivas, Patrick Forrester, Jose Hernandez and Tim Kopra, all mission specialists; along with European Space Agency astronaut Christer Fuglesang, mission specialist. Discovery landed at 5:53 p.m. (PDT) on Sept. 11, 2009 to end the STS-128 mission, completing its almost 14-day journey of more than 5.7 million miles in space. The landing was diverted to California due to marginal weather at the Kennedy Space Center. Discovery?s mission featured three spacewalks and the delivery of two refrigerator-sized science racks to the space station. One rack will be used to conduct experiments on materials such as metals, glasses and ceramics. The results from these experiments could lead to the development of better materials on Earth. The other rack will be used for fluid physics research. Understanding how fluids react in microgravity could lead to improved designs for fuel tanks, water systems and other fluid-based systems.

sts128-s-046

NASA Image and Video Library

2009-09-11

STS128-S-046 (11 Sept. 2009) --- Space Shuttle Discovery?s main landing gear touches down at NASA's Dryden Flight Research Center at Edwards Air Force Base in California, concluding a successful mission to the International Space Station. Onboard are NASA astronauts Rick Sturckow, commander; Kevin Ford, pilot; John ?Danny? Olivas, Patrick Forrester, Jose Hernandez and Tim Kopra, all mission specialists; along with European Space Agency astronaut Christer Fuglesang, mission specialist. Discovery landed at 5:53 p.m. (PDT) on Sept. 11, 2009 to end the STS-128 mission, completing its almost 14-day journey of more than 5.7 million miles in space. The landing was diverted to California due to marginal weather at the Kennedy Space Center. Discovery?s mission featured three spacewalks and the delivery of two refrigerator-sized science racks to the space station. One rack will be used to conduct experiments on materials such as metals, glasses and ceramics. The results from these experiments could lead to the development of better materials on Earth. The other rack will be used for fluid physics research. Understanding how fluids react in microgravity could lead to improved designs for fuel tanks, water systems and other fluid-based systems.

Implementation of a Water Flow Control System into the ISS'S Planned Fluids & Combustion Facility

NASA Technical Reports Server (NTRS)

Edwards, Daryl A.

2003-01-01

The Fluids and Combustion Facility (FCF) will become an ISS facility capable of performing basic combustion and fluids research. The facility consists of two independent payload racks specifically configured to support multiple experiments over the life of the ISS. Both racks will depend upon the ISS's Moderate Temperature Loop (MTL) for removing waste heat generated by the avionics and experiments operating within the racks. By using the MTL, constraints are imposed by the ISS vehicle on how the coolant resource is used. On the other hand, the FCF depends upon effective thermal control for maximizing life of the hardware and for supplying proper boundary conditions for the experiments. In the implementation of a design solution, significant factors in the selection of the hardware included ability to measure and control relatively low flow rates, ability to throttle flow within the time constraints of the ISS MTL, conserve energy usage, observe low mass and small volume requirements. An additional factor in the final design solution selection was considering how the system would respond to a loss of power event. This paper describes the method selected to satisfy the FCF design requirements while maintaining the constraints applied by the ISS vehicle.

EXPRESS Rack Overview

NASA Technical Reports Server (NTRS)

Sledd, Annette M.; Mueller, Charles W.

1999-01-01

The EXpedite the PRocessing of Experiments to Space Station or EXPRESS Rack System, was developed to provide Space Station accommodations for small, subrack payloads. The EXPRESS Rack accepts Space Shuttle middeck locker type payloads and International Subrack Interface Standard (ISIS) Drawer payloads, allowing previously flown payloads an opportunity to transition to the International Space Station. The EXPRESS Rack provides power, data, command and control, video, water cooling, air cooling, vacuum exhaust, and Nitrogen supply to payloads. The EXPRESS Rack system also includes transportation racks to transport payloads to and from the Space Station, Suitcase Simulators to allow a payload developer to verify power and data interfaces at the development site, Functional Checkout Units to allow Payload checkout at KSC prior to launch, and trainer racks for the astronauts to learn how to operate the EXPRESS Racks prior to flight. Standard hardware and software interfaces provided by the EXPRESS Rack simplify the analytical and physical integration processes, and facilitates simpler ISS payload development. The EXPRESS Rack has also formed the basis for the U.S. Life Sciences payload racks on Space Station.

Combustion Integration Rack (CIR)/FLame Extinguishment Experiment (FLEX)-2J Fiber Replace

NASA Image and Video Library

2015-08-20

ISS044E064666 (08/20/2015) --- NASA astronaut Kjell Lindgren replaces items inside the Multi-user Droplet Combustion Apparatus found inside the station’s Combustion Integrated Rack (CIR.) The CIR houses hardware capable of performing combustion experiments to further research of combustion in microgravity.

Microgravity

NASA Image and Video Library

2000-01-30

Engineers from NASA's Glenn Research Center demonstrate the access to one of the experiment racks planned for the U.S. Destiny laboratory module on the International Space Station (ISS). This mockup has the full diameter, full corridor width, and half the length of the module. The mockup includes engineering mockups of the Fluids and Combustion Facility being developed by NASA's Glenn Research Center. (The full module will be six racks long; the mockup is three racks long). Listening at left (coat and patterned tie) is John-David Bartoe, ISS research manager at NASA's Johnson Space Center and a payload specialist on Spacelab 2 mission (1985). Photo credit: NASA/Marshall Space Flight Center (MSFC)

Space Station Furnace Facility. Experiment/Facility Requirements Document (E/FRD), volume 2, appendix 5

NASA Technical Reports Server (NTRS)

Kephart, Nancy

1992-01-01

The function of the Space Station Furnace Facility (SSFF) is to support materials research into the crystal growth and solidification processes of electronic and photonic materials, metals and alloys, and glasses and ceramics. To support this broad base of research requirements, the SSFF will employ a variety of furnace modules operated, regulated, and supported by a core of common subsystems. Furnace modules may be reconfigured or specifically developed to provide unique solidifcation conditions for each set of experiments. The SSFF modular approach permits the addition of new or scaled-up furnace modules to support the evolution of the facility as new science requirements are identified. The SSFF Core is of modular design to permit augmentation for enhanced capabilities. The fully integrated configuration of the SSFF will consist of three racks with the capability of supporting up to two furnace modules per rack. The initial configuration of the SSFF will consist of two of the three racks and one furnace module. This Experiment/Facility Requirements Document (E/FRD) describes the integrated facility requirements for the Space Station Freedom (SSF) Integrated Configuration-1 (IC1) mission. The IC1 SSFF will consist of two racks: the Core Rack, with the centralized subsystem equipment, and the Experiment Rack-1, with Furnace Module-1 and the distributed subsystem equipment to support the furnace.

Experiment/facility requirements document for the Space Station Furnace Facility. Section 1: Integrated configuration

NASA Astrophysics Data System (ADS)

1992-05-01

The function of the Space Station Furnace Facility (SSFF) is to support materials research into the crystal growth and solidification processes of electronic and photonic materials, metals and alloys, and glasses and ceramics. To support this broad base of research requirements, the SSFF will employ a variety of furnace modules which will be operated, regulated, and supported by a core of common subsystems. Furnace modules may be reconfigured or specifically developed to provide unique solidification conditions for each set of experiments. The SSFF modular approach permits the addition of new or scaled-up furnace modules to support the evolution of the facility as new science requirements are identified. The SSFF Core is of modular design to permit augmentation for enhanced capabilities. The fully integrated configuration of the SSFF will consist of three racks with the capability of supporting up to two furnace modules per rack. The initial configuration of the SSFF will consist of two of the three racks and one furnace module. This Experiment/Facility Requirements Document (E/FRD) describes the integrated facility requirements for the Space Station Freedom (SSF) Integrated Configuration-1 (IC1) mission. The IC1 SSFF will consist of two racks: the Core Rack, with the centralized subsystem equipment; and the Experiment Rack-1, with Furnace Module-1 and the distributed subsystem equipment to support the furnace. The SSFF support functions are provided by the following Core subsystems: power conditioning and distribution subsystem (SSFF PCDS); data management subsystem (SSFF DMS); thermal control Subsystem (SSFF TCS); gas distribution subsystem (SSFF GDS); and mechanical structures subsystem (SSFF MSS).

Experiment/facility requirements document for the Space Station Furnace Facility. Section 1: Integrated configuration

NASA Technical Reports Server (NTRS)

1992-01-01

The function of the Space Station Furnace Facility (SSFF) is to support materials research into the crystal growth and solidification processes of electronic and photonic materials, metals and alloys, and glasses and ceramics. To support this broad base of research requirements, the SSFF will employ a variety of furnace modules which will be operated, regulated, and supported by a core of common subsystems. Furnace modules may be reconfigured or specifically developed to provide unique solidification conditions for each set of experiments. The SSFF modular approach permits the addition of new or scaled-up furnace modules to support the evolution of the facility as new science requirements are identified. The SSFF Core is of modular design to permit augmentation for enhanced capabilities. The fully integrated configuration of the SSFF will consist of three racks with the capability of supporting up to two furnace modules per rack. The initial configuration of the SSFF will consist of two of the three racks and one furnace module. This Experiment/Facility Requirements Document (E/FRD) describes the integrated facility requirements for the Space Station Freedom (SSF) Integrated Configuration-1 (IC1) mission. The IC1 SSFF will consist of two racks: the Core Rack, with the centralized subsystem equipment; and the Experiment Rack-1, with Furnace Module-1 and the distributed subsystem equipment to support the furnace. The SSFF support functions are provided by the following Core subsystems: power conditioning and distribution subsystem (SSFF PCDS); data management subsystem (SSFF DMS); thermal control Subsystem (SSFF TCS); gas distribution subsystem (SSFF GDS); and mechanical structures subsystem (SSFF MSS).

Microgravity

NASA Image and Video Library

2000-01-31

The combustion chamber for the Combustion Integrated Rack section of the Fluids and Combustion Facility (FCF) is shown extracted for servicing and with the optical bench rotated 90 degrees for access to the rear elements. The FCF will be installed, in phases, in the Destiny, the U.S. Laboratory Module of the International Space Station (ISS), and will accommodate multiple users for a range of investigations. This is an engineering mockup; the flight hardware is subject to change as designs are refined. The FCF is being developed by the Microgravity Science Division (MSD) at the NASA Glenn Research Center. (Photo credit: NASA/Marshall Space Flight Center)

EXPRESS Rack: The Extension of International Space Station Resources for Multi-Discipline Subrack Payloads

NASA Technical Reports Server (NTRS)

Sledd, Annette; Danford, Mike; Key, Brian

2002-01-01

The EXpedite the PRocessing of Experiments to Space Station or EXPRESS Rack System was developed to provide Space Station accommodations for subrack payloads. The EXPRESS Rack accepts Space Shuttle middeck locker type payloads and International Subrack Interface Standard (ISIS) Drawer payloads, allowing previously flown payloads an opportunity to transition to the International Space Station. The EXPRESS Rack provides power, data command and control, video, water cooling, air cooling, vacuum exhaust, and Nitrogen supply to payloads. The EXPRESS Rack system also includes transportation racks to transport payloads to and from the Space Station, Suitcase Simulators to allow a payload developer to verify data interfaces at the development site, Functional Checkout Units to allow payload checkout at KSC prior to launch, and trainer racks for the astronauts to learn how to operate the EXPRESS Racks prior to flight. Standard hardware and software interfaces provided by the EXPRESS Rack simplify the integration processes, and facilitate simpler ISS payload development. Whereas most ISS Payload facilities are designed to accommodate one specific type of science, the EXPRESS Rack is designed to accommodate multi-discipline research within the same rack allowing for the independent operation of each subrack payload. On-orbit operations began with the EXPRESS Rack Project on April 24, 2001, with one rack operating continuously to support long-running payloads. The other on-orbit EXPRESS Racks operate based on payload need and resource availability. Sustaining Engineering and Logistics and Maintenance functions are in place to maintain operations and to provide software upgrades.

An EXPRESS Rack Overview and Support for Microgravity Research on the International Space Station (ISS)

NASA Technical Reports Server (NTRS)

Pelfrey, Joseph J.; Jordan, Lee P.

2008-01-01

The EXpedite the PRocessing of Experiments to Space Station or EXPRESS Rack System has provided accommodations and facilitated operations for microgravity-based research payloads for over 6 years on the International Space Station (ISS). The EXPRESS Rack accepts Space Shuttle middeck type lockers and International Subrack Interface Standard (ISIS) drawers, providing a modular-type interface on the ISS. The EXPRESS Rack provides 28Vdc power, Ethernet and RS-422 data interfaces, thermal conditioning, vacuum exhaust, and Nitrogen supply for payload use. The EXPRESS Rack system also includes payload checkout capability with a flight rack or flight rack emulator prior to launch, providing a high degree of confidence in successful operations once an-orbit. In addition, EXPRESS trainer racks are provided to support crew training of both rack systems and subrack operations. Standard hardware and software interfaces provided by the EXPRESS Rack simplify the integration processes for ISS payload development. The EXPRESS Rack is designed to accommodate multidiscipline research, allowing for the independent operation of each subrack payload within a single rack. On-orbit operations began for the EXPRESS Rack Project on April 24, 2001, with one rack operating continuously to support high-priority payloads. The other on-orbit EXPRESS Racks operate based on payload need and resource availability. Over 50 multi-discipline payloads have now been supported on-orbit by the EXPRESS Rack Program. Sustaining engineering, logistics, and maintenance functions are in place to maintain hardware, operations and provide software upgrades. Additional EXPRESS Racks are planned for launch prior to ISS completion in support of long-term operations and the planned transition of the U.S. Segment to a National Laboratory.

EXPRESS Rack Mockup

NASA Technical Reports Server (NTRS)

2002-01-01

The EXPRESS Rack is a standardized payload rack system that transports, stores, and supports experiments aboard the International Space Station (ISS). EXPRESS stands for EXpedite the PRocessing of Experiments to the Space Station, reflecting the fact that this system was developed specifically to maximize the Station's research capabilities. The EXPRESS Rack system supports science payloads in several disciplines, including biology, chemistry, physics, ecology, and medicine. With the EXPRESS Rack, getting experiments to space has never been easier or more affordable. With its standardized hardware interfaces and streamlined approach, the EXPRESS Rack enables quick, simple integration of multiple payloads aboard the ISS. The system is comprised of elements that remain on the ISS, as well as elements that travel back and forth between the ISS and Earth via the Space Shuttle. The Racks stay on orbit continually, while experiments are exchanged in and out of the EXPRESS Racks as needed, remaining on the ISS for three months to several years, depending on the experiment's time requirements. A refrigerator-sized Rack can be divided into segments, as large as half of an entire rack or as small as a bread box. Payloads within EXPRESS Racks can operate independently of each other, allowing for differences in temperature, power levels, and schedules. Experiments contained within EXPRESS Racks may be controlled by the ISS crew or remotely by the Payload Rack Officer at the Payload Operations Center at the Marshall Space Flight Center (MSFC). The EXPRESS Rack system was developed by MSFC and built by the Boeing Co. in Huntsville, Alabama. Eight EXPRESS Racks are being built for use on the ISS.

Carbon Dioxide Dispersion in the Combustion Integrated Rack Simulated Numerically

NASA Technical Reports Server (NTRS)

Wu, Ming-Shin; Ruff, Gary A.

2004-01-01

When discharged into an International Space Station (ISS) payload rack, a carbon dioxide (CO2) portable fire extinguisher (PFE) must extinguish a fire by decreasing the oxygen in the rack by 50 percent within 60 sec. The length of time needed for this oxygen reduction throughout the rack and the length of time that the CO2 concentration remains high enough to prevent the fire from reigniting is important when determining the effectiveness of the response and postfire procedures. Furthermore, in the absence of gravity, the local flow velocity can make the difference between a fire that spreads rapidly and one that self-extinguishes after ignition. A numerical simulation of the discharge of CO2 from PFE into the Combustion Integrated Rack (CIR) in microgravity was performed to obtain the local velocity and CO2 concentration. The complicated flow field around the PFE nozzle exits was modeled by sources of equivalent mass and momentum flux at a location downstream of the nozzle. The time for the concentration of CO2 to reach a level that would extinguish a fire anywhere in the rack was determined using the Fire Dynamics Simulator (FDS), a computational fluid dynamics code developed by the National Institute of Standards and Technology specifically to evaluate the development of a fire and smoke transport. The simulation shows that CO2, as well as any smoke and combustion gases produced by a fire, would be discharged into the ISS cabin through the resource utility panel at the bottom of the rack. These simulations will be validated by comparing the results with velocity and CO2 concentration measurements obtained during the fire suppression system verification tests conducted on the CIR in March 2003. Once these numerical simulations are validated, portions of the ISS labs and living areas will be modeled to determine the local flow conditions before, during, and after a fire event. These simulations can yield specific information about how long it takes for smoke and combustion gases produced by a fire to reach a detector location, how large the fire would be when the detector alarms, and the behavior of the fire until it has been extinguished. This new capability could then be used to optimize the location of fire detectors and fire-suppression ports as well as to evaluate the effectiveness of fire suppressants and response strategies. Numerical data collected from these simulations could also be used to develop a virtual reality fire event for crew training and fire safety awareness. This work is funded by NASA's Bioastronautics Initiative, which has the objective of ensuring and enhancing the health, safety, and performance of humans in space. As part of this initiative, the Microgravity Combustion Science Branch at the NASA Glenn Research Center is conducting spacecraft fire safety research to significantly improve fire safety on inhabited spacecraft.

The Extension of ISS Resources for Multi-Discipline Subrack Payloads

NASA Technical Reports Server (NTRS)

Sledd, Annette M.; Gilbert, Paul A. (Technical Monitor)

2002-01-01

The EXpedite the processing of Experiments to Space Station or EXPRESS Rack System was developed to provide Space Station accommodations for subrack payloads. The EXPRESS Rack accepts Space Shuttle middeck locker type payloads and International Subrack Interface Standard (ISIS) Drawer payloads, allowing previously flown payloads an opportunity to transition to the International Space Station. The EXPRESS Rack provides power, data command and control, video, water cooling, air cooling, vacuum exhaust, and Nitrogen supply to payloads. The EXPRESS Rack system also includes transportation racks to transport payloads to and from the Space Station, Suitcase Simulators to allow a payload developer to verify data interfaces at the development site, Functional Checkout Units to allow payload checkout at KSC prior to launch, and trainer racks for the astronauts to learn how to operate the EXPRESS Racks prior to flight. Standard hardware and software interfaces provided by the EXPRESS Rack simplify the integration processes, and facilitate simpler ISS payload development. Whereas most ISS Payload facilities are designed to accommodate one specific type of science, the EXPRESS Rack is designed to accommodate multi-discipline research within the same rack allowing for the independent operation of each subrack payload. On-orbit operations began with the EXPRESS Rack Project on April 24, 2001, with one rack operating continuously to support long-running payloads. The other on-orbit EXPRESS Racks operate based on payload need and resource availability. Sustaining Engineering and Logistics and Maintenance functions are in place to maintain operations and to provide software upgrades.

Development and Capabilities of ISS Flow Boiling and Condensation Experiment

NASA Technical Reports Server (NTRS)

Nahra, Henry; Hasan, Mohammad; Balasubramaniam, R.; Patania, Michelle; Hall, Nancy; Wagner, James; Mackey, Jeffrey; Frankenfield, Bruce; Hauser, Daniel; Harpster, George;

Performance Evaluation of the International Space Station Flow Boiling and Condensation Experiment (FBCE) Test Facility

NASA Technical Reports Server (NTRS)

Hasan, Mohammad; Balasubramaniam, R.; Nahra, Henry; Mackey, Jeff; Hall, Nancy; Frankenfield, Bruce; Harpster, George; May, Rochelle; Mudawar, Issam; Kharangate, Chirag R.;

International Space Station (ISS)

NASA Image and Video Library

2001-05-14

Astronaut James S. Voss, Expedition Two flight engineer, works with a series of cables on the EXPRESS Rack in the United State's Destiny laboratory on the International Space Station (ISS). The EXPRESS Rack is a standardized payload rack system that transports, stores, and supports experiments aboard the ISS. EXPRESS stands for EXpedite the PRocessing of Experiments to the Space Station, reflecting the fact that this system was developed specifically to maximize the Station's research capabilities. The EXPRESS Rack system supports science payloads in several disciplines, including biology, chemistry, physics, ecology, and medicine. With the EXPRESS Rack, getting experiments to space has never been easier or more affordable. With its standardized hardware interfaces and streamlined approach, the EXPRESS Rack enables quick, simple integration of multiple payloads aboard the ISS. The system is comprised of elements that remain on the ISS, as well as elements that travel back and forth between the ISS and Earth via the Space Shuttle.

Astronaut James S. Voss Performs Tasks in the Destiny Laboratory

NASA Technical Reports Server (NTRS)

2001-01-01

Astronaut James S. Voss, Expedition Two flight engineer, works with a series of cables on the EXPRESS Rack in the United State's Destiny laboratory on the International Space Station (ISS). The EXPRESS Rack is a standardized payload rack system that transports, stores, and supports experiments aboard the ISS. EXPRESS stands for EXpedite the PRocessing of Experiments to the Space Station, reflecting the fact that this system was developed specifically to maximize the Station's research capabilities. The EXPRESS Rack system supports science payloads in several disciplines, including biology, chemistry, physics, ecology, and medicine. With the EXPRESS Rack, getting experiments to space has never been easier or more affordable. With its standardized hardware interfaces and streamlined approach, the EXPRESS Rack enables quick, simple integration of multiple payloads aboard the ISS. The system is comprised of elements that remain on the ISS, as well as elements that travel back and forth between the ISS and Earth via the Space Shuttle.

Graphical explanation in an expert system for Space Station Freedom rack integration

NASA Technical Reports Server (NTRS)

Craig, F. G.; Cutts, D. E.; Fennel, T. R.; Purves, B.

1990-01-01

The rationale and methodology used to incorporate graphics into explanations provided by an expert system for Space Station Freedom rack integration is examined. The rack integration task is typical of a class of constraint satisfaction problems for large programs where expertise from several areas is required. Graphically oriented approaches are used to explain the conclusions made by the system, the knowledge base content, and even at more abstract levels the control strategies employed by the system. The implemented architecture combines hypermedia and inference engine capabilities. The advantages of this architecture include: closer integration of user interface, explanation system, and knowledge base; the ability to embed links to deeper knowledge underlying the compiled knowledge used in the knowledge base; and allowing for more direct control of explanation depth and duration by the user. The graphical techniques employed range from simple statis presentation of schematics to dynamic creation of a series of pictures presented motion picture style. User models control the type, amount, and order of information presented.

Ground based ISS payload microgravity disturbance assessments.

PubMed

McNelis, Anne M; Heese, John A; Samorezov, Sergey; Moss, Larry A; Just, Marcus L

2005-01-01

In order to verify that the International Space Station (ISS) payload facility racks do not disturb the microgravity environment of neighboring facility racks and that the facility science operations are not compromised, a testing and analytical verification process must be followed. Currently no facility racks have taken this process from start to finish. The authors are participants in implementing this process for the NASA Glenn Research Center (GRC) Fluids and Combustion Facility (FCF). To address the testing part of the verification process, the Microgravity Emissions Laboratory (MEL) was developed at GRC. The MEL is a 6 degree of freedom inertial measurement system capable of characterizing inertial response forces (emissions) of components, sub-rack payloads, or rack-level payloads down to 10(-7) g's. The inertial force output data, generated from the steady state or transient operations of the test articles, are utilized in analytical simulations to predict the on-orbit vibratory environment at specific science or rack interface locations. Once the facility payload rack and disturbers are properly modeled an assessment can be made as to whether required microgravity levels are achieved. The modeling is utilized to develop microgravity predictions which lead to the development of microgravity sensitive ISS experiment operations once on-orbit. The on-orbit measurements will be verified by use of the NASA GRC Space Acceleration Measurement System (SAMS). The major topics to be addressed in this paper are: (1) Microgravity Requirements, (2) Microgravity Disturbers, (3) MEL Testing, (4) Disturbance Control, (5) Microgravity Control Process, and (6) On-Orbit Predictions and Verification. Published by Elsevier Ltd.

Mechanically-reattachable liquid-cooled cooling apparatus

DOEpatents

Arney, Susanne; Cheng, Jen-Hau; Kolodner, Paul R; Kota-Venkata, Krishna-Murty; Scofield, William; Salamon, Todd R; Simon, Maria E

2013-09-24

An apparatus comprising a rack having a row of shelves, each shelf supporting an electronics circuit board, each one of the circuit boards being manually removable from the shelve supporting the one of the circuit boards and having a local heat source thereon. The apparatus also comprises a cooler attached to the rack and being able to circulate a cooling fluid around a channel forming a closed loop. The apparatus further comprises a plurality of heat conduits, each heat conduit being located over a corresponding one of the circuit boards and forming a path to transport heat from the local heat source of the corresponding one of the circuit boards to the cooler. Each heat conduit is configured to be manually detachable from the cooler or the circuit board, without breaking a circulation pathway of the fluid through the cooler.

Microgravity Disturbance Predictions in the Combustion Integrated Rack

NASA Astrophysics Data System (ADS)

Just, M.; Grodsinsky, Carlos M.

2002-01-01

This paper will focus on the approach used to characterize microgravity disturbances in the Combustion Integrated Rack (CIR), currently scheduled for launch to the International Space Station (ISS) in 2005. Microgravity experiments contained within the CIR are extremely sensitive to vibratory and transient disturbances originating on-board and off-board the rack. Therefore, several techniques are implemented to isolate the critical science locations from external vibration. A combined testing and analysis approach is utilized to predict the resulting microgravity levels at the critical science location. The major topics to be addressed are: 1) CIR Vibration Isolation Approaches, 2) Disturbance Sources and Characterization, 3) Microgravity Predictive Modeling, 4) Science Microgravity Requirements, 6) Microgravity Control, and 7) On-Orbit Disturbance Measurement. The CIR is using the Passive Rack Isolation System (PaRIS) to isolate the rack from offboard rack disturbances. By utilizing this system, CIR is connected to the U.S. Lab module structure by either 13 or 14 umbilical lines and 8 spring / damper isolators. Some on-board CIR disturbers are locally isolated by grommets or wire ropes. CIR's environmental and science on board support equipment such as air circulation fans, pumps, water flow, air flow, solenoid valves, and computer hard drives cause disturbances within the rack. These disturbers along with the rack structure must be characterized to predict whether the on-orbit vibration levels during experimentation exceed the specified science microgravity vibration level requirements. Both vibratory and transient disturbance conditions are addressed. Disturbance levels/analytical inputs are obtained for each individual disturber in a "free floating" condition in the Glenn Research Center (GRC) Microgravity Emissions Lab (MEL). Flight spare hardware is tested on an Orbital Replacement Unit (ORU) basis. Based on test and analysis, maximum disturbance level allocations are developed for each ORU. The worst-case disturbances are input into an on-orbit analytical dynamic model of the rack. These models include both NASTRAN and MATLAB Simulink models , which include eigenvector and frequency inputs of the rack rigid body modes, the rack umbilical modes, and the racks' structural modes. The disturbance areas and science locations need to be modeled accurately to give valid predictions. The analytically determined microgravity vibration levels are compared to the CIR science requirements contained in the FCF Science Requirements Envelope Document (SRED). The predicted levels will be compared with the on-orbit measurements provided by the Space Acceleration Measurement System (SAMS) sensor, which is to be mounted on the CIR optics bench.

FRACTIONATING COLUMN PRODUCT COLLECTOR CONTROL

DOEpatents

Paxson, G.D. Jr.

1964-03-10

Means for detecting minute fluid products from a chemical separation column and for advancing a collector tube rack in order to automatically separate and collect successive fractionated products are described. A charge is imposed on the forming drops at the column orifice to create an electric field as the drop falls in the vicinity of a sensing plate. The field is detected by an electrometer tube coupled to the plate causing an output signal to actuate rotation of a collector turntable rack, thereby positioning new collectors under the orifice. The invention provides reliable automatic collection independent of drop size, rate of fall, or chemical composition. (AEC)

Increasing the usefulness of Shuttle with SPACEHAB

NASA Astrophysics Data System (ADS)

Stone, Barbara A.; Rossi, David A.

1992-08-01

SPACEHAB is a pressurized laboratory, approximately 10 feet long and 13 feet in diameter, which fits in the forward position of the Shuttle payload bay and connects to the crew compartment through the Orbiter airlock. SPACEHAB modules may contain up to 61 standard middeck lockers, providing 1100 cubic feet of pressurized work space. SPACEHAB'S capacity offers crew-tended access to the microgravity environment for experimentation, technology development, and small-scale production. The modules are designed to facilitate the user's ability to quickly and inexpensively develop and integrate a microgravity payload. Payloads are typically integrated into the SPACEHAB module in standard SPACEHAB lockers or SPACEHAB racks. Lockers are designed to offer identical user interfaces as standard Space Shuttle middeck lockers. SPACEHAB racks are interchangeable with Space Station Freedom racks, allowing hardware to be qualified for early station use.

Microgravity Science Glovebox

NASA Technical Reports Server (NTRS)

2001-01-01

Computer-generated drawing shows the relative scale and working space for the Microgravity Science Glovebox (MSG) being developed by NASA and the European Space Agency for science experiments aboard the International Space Station (ISS). The person at the glovebox repesents a 95th percentile American male. The MSG will be deployed first to the Destiny laboratory module and later will be moved to ESA's Columbus Attached Payload Module. Each module will be filled with International Standard Payload Racks (green) attached to standoff fittings (yellow) that hold the racks in position. Destiny is six racks in length. The MSG is being developed by the European Space Agency and NASA to provide a large working volume for hands-on experiments aboard the International Space Station. Scientists will use the MSG to carry out multidisciplinary studies in combustion science, fluid physics and materials science. The MSG is managed by NASA's Marshall Space Flight Center. (Credit: NASA/Marshall)

CM-2 Environmental / Modal Testing of Spacehab Racks

NASA Technical Reports Server (NTRS)

McNelis, Mark E.; Goodnight, Thomas W.; Farkas, Michael A.

2001-01-01

Combined environmental/modal vibration testing has been implemented at the NASA Glenn Research Center's Structural Dynamics Laboratory. The benefits of combined vibration testing are that it facilitates test article modal characterization and vibration qualification testing. The Combustion Module-2 (CM-2) is a space experiment that launches on Shuttle mission STS 107 in the SPACEHAB Research Double Module. The CM-2 flight hardware is integrated into a SPACEHAB single and double rack. CM-2 rack level combined vibration testing was recently completed on a shaker table to characterize the structure's modal response and verify the random vibration response. Control accelerometers and limit force gauges, located between the fixture and rack interface, were used to verify the input excitation. Results of the testing were used to verify the loads and environments for flight on the Shuttle.

Wakata working on the CIR

NASA Image and Video Library

2014-02-05

ISS038-E-042747 (5 Feb. 2014) --- Japan Aerospace Exploration Agency astronaut Koichi Wakata, Expedition 38 flight engineer, works on the Combustion Integrated Rack (CIR) in the Destiny laboratory of the International Space Station. This research rack, which includes an optics bench, combustion chamber, fuel and oxidizer control and five different cameras, allows a variety of combustion experiments to be performed safely aboard the station.

Wakata working on the CIR

NASA Image and Video Library

2014-02-05

ISS038-E-042754 (5 Feb. 2014) --- Japan Aerospace Exploration Agency astronaut Koichi Wakata, Expedition 38 flight engineer, works on the Combustion Integrated Rack (CIR) in the Destiny laboratory of the International Space Station. This research rack, which includes an optics bench, combustion chamber, fuel and oxidizer control and five different cameras, allows a variety of combustion experiments to be performed safely aboard the station.

Wakata working on the CIR

NASA Image and Video Library

2014-02-05

ISS038-E-042758 (5 Feb. 2014) --- Japan Aerospace Exploration Agency astronaut Koichi Wakata, Expedition 38 flight engineer, works on the Combustion Integrated Rack (CIR) in the Destiny laboratory of the International Space Station. This research rack, which includes an optics bench, combustion chamber, fuel and oxidizer control and five different cameras, allows a variety of combustion experiments to be performed safely aboard the station.

CM-2 Environmental/Modal Testing of SPACEHAB Racks

NASA Technical Reports Server (NTRS)

McNelis, Mark E.; Goodnight, Thomas W.

2001-01-01

Combined environmental/modal vibration testing has been implemented at the NASA Glenn Research Center's Structural Dynamics Laboratory. The benefits of combined vibration testing are that it facilitates test article modal characterization and vibration qualification testing. The Combustion Module-2 (CM-2) is a space experiment that will launch on shuttle mission STS-107 in the SPACEHAB Research Double Module. The CM-2 flight hardware is integrated into a SPACEHAB single and double rack. CM-2 rack-level combined vibration testing was recently completed on a shaker table to characterize the structure's modal response and verify the random vibration response. Control accelerometers and limit force gauges, located between the fixture and rack interface, were used to verify the input excitation. Results of the testing were used to verify the loads and environments for flight on the shuttles.

DomeGene Sample Removal from Cell Biology Experiment Facility (CBEF)

NASA Image and Video Library

2009-03-28

ISS018-E-044235 (28 March 2009) --- Japan Aerospace Exploration Agency (JAXA) astronaut Koichi Wakata, Expedition 18/19 flight engineer, works on an experiment at the Ryutai fluid science experiment rack in the Kibo laboratory of the International Space Station.

Payload Specialist Byron K. Lichtenberg working in the Spacelab

NASA Image and Video Library

1983-11-28

STS009-125-427 (28 Nov 1983) --- Payload Specialist Byron K. Lichtenberg carries out an experiment at the fluid physics module on the busy materials science double rack facility. Two beverage containers can be seen just above the biomedical engineer's head.

Cassidy in JEM

NASA Image and Video Library

2013-07-24

ISS036-E-025489 (24 July 2013) --- NASA astronaut Chris Cassidy, Expedition 36 flight engineer, performs in-flight maintenance on the Marangoni Inside experiment in the Fluid Physics Experiment Facility (FPEF) which is part of a Japanese science rack in the International Space Station?s Kibo laboratory.

Cassidy in JEM

NASA Image and Video Library

2013-07-24

ISS036-E-025487 (24 July 2013) --- NASA astronaut Chris Cassidy, Expedition 36 flight engineer, performs in-flight maintenance on the Marangoni Inside experiment in the Fluid Physics Experiment Facility (FPEF) which is part of a Japanese science rack in the International Space Station?s Kibo laboratory.

Cassidy in JEM

NASA Image and Video Library

2013-07-24

ISS036-E-025484 (24 July 2013) --- NASA astronaut Chris Cassidy, Expedition 36 flight engineer, performs in-flight maintenance on the Marangoni Inside experiment in the Fluid Physics Experiment Facility (FPEF) which is part of a Japanese science rack in the International Space Station?s Kibo laboratory.

Cassidy in JEM

NASA Image and Video Library

2013-07-24

ISS036-E-025491 (24 July 2013) --- NASA astronaut Chris Cassidy, Expedition 36 flight engineer, performs in-flight maintenance on the Marangoni Inside experiment in the Fluid Physics Experiment Facility (FPEF) which is part of a Japanese science rack in the International Space Station?s Kibo laboratory.

Time lapse of CIR rack rotate and R&R

NASA Image and Video Library

2014-07-21

ISS040-E-071994 (21 July 2014) --- In the International Space Station’s Destiny laboratory, NASA astronaut Reid Wiseman, Expedition 40 flight engineer, sets up the Combustion Integrated Rack (CIR) for more ground-commanded tests. This facility, which includes an optics bench, combustion chamber, fuel and oxidizer control and five different cameras, allows a variety of combustion experiments to be performed safely aboard the station.

Time lapse of CIR rack rotate and R&R

NASA Image and Video Library

2014-07-21

ISS040-E-072156 (21 July 2014) --- In the International Space Station’s Destiny laboratory, NASA astronaut Reid Wiseman, Expedition 40 flight engineer, sets up the Combustion Integrated Rack (CIR) for more ground-commanded tests. This facility, which includes an optics bench, combustion chamber, fuel and oxidizer control and five different cameras, allows a variety of combustion experiments to be performed safely aboard the station.

Time lapse of CIR rack rotate and R&R

NASA Image and Video Library

2014-07-21

ISS040-E-072228 (21 July 2014) --- In the International Space Station’s Destiny laboratory, NASA astronaut Reid Wiseman, Expedition 40 flight engineer, sets up the Combustion Integrated Rack (CIR) for more ground-commanded tests. This facility, which includes an optics bench, combustion chamber, fuel and oxidizer control and five different cameras, allows a variety of combustion experiments to be performed safely aboard the station.

Combustion Research aboard the ISS Utilizing the Combustion Integrated Rack and Microgravity Science Glovebox

NASA Astrophysics Data System (ADS)

Sutliff, T. J.; Otero, A. M.; Urban, D. L.

2002-01-01

The Physical Sciences Research Program of NASA has chartered a broad suite of peer-reviewed research investigating both fundamental combustion phenomena and applied combustion research topics. Fundamental research provides insights to develop accurate simulations of complex combustion processes and allows developers to improve the efficiency of combustion devices, to reduce the production of harmful emissions, and to reduce the incidence of accidental uncontrolled combustion (fires, explosions). The applied research benefit humans living and working in space through its fire safety program. The Combustion Science Discipline is implementing a structured flight research program utilizing the International Space Station (ISS) and two of its premier facilities, the Combustion Integrated Rack of the Fluids and Combustion Facility and the Microgravity Science Glovebox to conduct this space-based research. This paper reviews the current vision of Combustion Science research planned for International Space Station implementation from 2003 through 2012. A variety of research efforts in droplets and sprays, solid-fuels combustion, and gaseous combustion have been independently selected and critiqued through a series of peer-review processes. During this period, while both the ISS carrier and its research facilities are under development, the Combustion Science Discipline has synergistically combined research efforts into sub-topical areas. To conduct this research aboard ISS in the most cost effective and resource efficient manner, the sub-topic research areas are implemented via a multi-user hardware approach. This paper also summarizes the multi-user hardware approach and recaps the progress made in developing these research hardware systems. A balanced program content has been developed to maximize the production of fundamental and applied combustion research results within the current budgetary and ISS operational resource constraints. Decisions on utilizing the Combustion Integrated Rack and the Microgravity Science Glovebox are made based on facility capabilities and research requirements. To maximize research potential, additional research objectives are specified as desires a priori during the research design phase. These expanded research goals, which are designed to be achievable even with late addition of operational resources, allow additional research of a known, peer-endorsed scope to be conducted at marginal cost. Additional operational resources such as upmass, crewtime, data downlink bandwidth, and stowage volume may be presented by the ISS planners late in the research mission planning process. The Combustion Discipline has put in place plans to be prepared to take full advantage of such opportunities.

Computational fluid dynamics modeling of bun baking process under different oven load conditions.

PubMed

Tank, A; Chhanwal, N; Indrani, D; Anandharamakrishnan, C

2014-09-01

A computational fluid dynamics (CFD) model was developed to study the temperature profile of the bun during baking process. Evaporation-condensation mechanism and effect of the latent heat during phase change of water was incorporated in this model to represent actual bun baking process. Simulation results were validated with experimental measurements of bun temperature at two different positions. Baking process is completed within 20 min, after the temperature of crumb become stable at 98 °C. Further, this study was extended to investigate the effect of partially (two baking trays) loaded and fully loaded (eight baking trays) oven on temperature profile of bun. Velocity and temperature profile differs in partially loaded and fully loaded oven. Bun placed in top rack showed rapid baking while bun placed in bottom rack showed slower baking due to uneven temperature distribution in the oven. Hence, placement of bun inside the oven affects temperature of bun and consequently, the quality of the product.

Combined Cycle Engine Large-Scale Inlet for Mode Transition Experiments: System Identification Rack Hardware Design

NASA Technical Reports Server (NTRS)

Thomas, Randy; Stueber, Thomas J.

2013-01-01

The System Identification (SysID) Rack is a real-time hardware-in-the-loop data acquisition (DAQ) and control instrument rack that was designed and built to support inlet testing in the NASA Glenn Research Center 10- by 10-Foot Supersonic Wind Tunnel. This instrument rack is used to support experiments on the Combined-Cycle Engine Large-Scale Inlet for Mode Transition Experiment (CCE? LIMX). The CCE?LIMX is a testbed for an integrated dual flow-path inlet configuration with the two flow paths in an over-and-under arrangement such that the high-speed flow path is located below the lowspeed flow path. The CCE?LIMX includes multiple actuators that are designed to redirect airflow from one flow path to the other; this action is referred to as "inlet mode transition." Multiple phases of experiments have been planned to support research that investigates inlet mode transition: inlet characterization (Phase-1) and system identification (Phase-2). The SysID Rack hardware design met the following requirements to support Phase-1 and Phase-2 experiments: safely and effectively move multiple actuators individually or synchronously; sample and save effector control and position sensor feedback signals; automate control of actuator positioning based on a mode transition schedule; sample and save pressure sensor signals; and perform DAQ and control processes operating at 2.5 KHz. This document describes the hardware components used to build the SysID Rack including their function, specifications, and system interface. Furthermore, provided in this document are a SysID Rack effectors signal list (signal flow); system identification experiment setup; illustrations indicating a typical SysID Rack experiment; and a SysID Rack performance overview for Phase-1 and Phase-2 experiments. The SysID Rack described in this document was a useful tool to meet the project objectives.

Window Observational Rack Facility (WORF)

NASA Technical Reports Server (NTRS)

2002-01-01

Developed by Boeing, at the Marshall Space Flight Center (MSFC) Space Station Manufacturing building, the Window Observational Rack Facility (WORF) will help Space Station crews take some of the best photographs ever snapped from an orbiting spacecraft by eliminating glare and allowing researchers to control their cameras and other equipment from the ground. The WORF is designed to make the best possible use of the high-quality research window in the Space Station's U.S. Destiny laboratory module. Engineers at the MSFC proposed a derivative of the EXPRESS (Expedite the Processing of Experiments to the Space Station) Rack already used on the Space Station and were given the go-ahead. The EXPRESS rack can hold a wide variety of experiments and provide them with power, communications, data, cooling, fluids, and other utilities - all the things that Earth-observing experiment instruments would need. WORF will supply payloads with power, data, cooling, video downlink, and stable, standardized interfaces for mounting imaging instruments. Similar to specialized orbital observatories, the interior of the rack is sealed against light and coated with a special low-reflectant black paint, so payloads will be able to observe low-light-level subjects such as the faint glow of auroras. Cameras and remote sensing instruments in the WORF can be preprogrammed, controlled from the ground, or operated by a Station crewmember by using a flexible shroud designed to cinch tightly around the crewmember's waist. The WORF is scheduled to be launched aboard the STS-114 Space Shuttle mission in the year 2003.

Validation of Modified Wine-Rack Thermal Design for Nickel-Hydrogen Batteries in Landsat-7 Spacecraft Thermal Vacuum Test and in Flight

NASA Technical Reports Server (NTRS)

Choi, Michael K.

1999-01-01

A heritage wine-rack thermal/mechanical design for the nickel-hydrogen batteries was the baseline at the Landsat-7 Preliminary Design Review. An integrated thermal and power analysis of the batteries performed by the author in 1994 revealed that the maximum cell-to-cell gradient was 6.6 C. The author proposed modifying the heritage wine-rack design by enhancing heat conduction from cells to cells, and from cells to battery frame. At the 1995 Intersociety Energy Conversion Engineering Conference (IECEC), the author presented a paper on methods of modifying the wine-rack design. It showed that the modified wine-rack option, which uses a metallic filler, could reduce the maximum cell-to-cell temperature gradient to 1.30 C, and could also reduce the maximum cell temperature by as much as 80 C. That design concept was adopted by the Landsat7 Project Office, and a design change was made at the Critical Design Review. Results of the spacecraft thermal vacuum and thermal balance tests, and temperature data in flight show that the temperatures of the battery cells are very uniform. The maximum cell-to-cell gradient is 1.50 C. They validate the modified wine-rack thermal design.

Development of the Two Phase Flow Separator Experiment for a Reduced Gravity Aircraft Flight

NASA Technical Reports Server (NTRS)

Golliher, Eric; Gotti, Daniel; Owens, Jay; Gilkey, Kelly; Pham, Nang; Stehno, Philip

2016-01-01

The recent hardware development and testing of a reduced gravity aircraft flight experiment has provided valuable insights for the future design of the Two Phase Flow Separator Experiment (TPFSE). The TPFSE is scheduled to fly within the Fluids Integration Rack (FIR) aboard the International Space Station (ISS) in 2020. The TPFSE studies the operational limits of gas and liquid separation of passive cyclonic separators. A passive cyclonic separator utilizes only the inertia of the incoming flow to accomplish the liquid-gas separation. Efficient phase separation is critical for environmental control and life support systems, such as recovery of clean water from bioreactors, for long duration human spaceflight missions. The final low gravity aircraft flight took place in December 2015 aboard NASA's C9 airplane.

14 CFR 1214.810 - Integration of payloads.

Code of Federal Regulations, 2011 CFR

2011-01-01

... performing the following typical Spacelab-payload mission management functions: (1) Analytical design of the... integration of experiments into racks and/or onto pallets. (5) Provision of payload unique software for use...

Innovative Ballasted Flat Roof Solar PV Racking System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Peek, Richard T.

2014-12-15

The objective of this project was to reduce the cost of racking for PV solar on flat commercial rooftops. Cost reductions would come from both labor savings and material savings related to the installation process. The rack would need to accommodate the majority of modules available on the market. Cascade Engineering has a long history of converting traditional metal type applications over to plastic. Injection molding of plastics have numerous advantages including selection of resin for the application, placing the material exactly where it is needed, designing in features that will speed up the installation process, and weight reduction ofmore » the array. A plastic rack would need to meet the requirements of UL2703, Mounting systems, mounting devices, clamping/retention devices, and ground lugs for use with flat-plate photovoltaic modules and panels. Comparing original data to the end of project racking design, racking material costs were reduced 50% and labor costs reduced 64%. The racking product accommodates all 60 and 72 cell panels on the market, meets UL2703 requirements, contributes only 1.3 pounds per square foot of weight to the array, requires little ballast to secure the array, automatically grounds the module when the module is secured, stacks/nests well for shipping/fewer lifts to the roof, provides integrated wire routing, allows water to drain on the roof, and accommodates various seismic roof connections. Project goals were achieved as noted in the original funding application.« less

Test Rack Development for Extended Operation of Advanced Stirling Convertors at NASA Glenn Research Center

NASA Technical Reports Server (NTRS)

Dugala, Gina M.

2010-01-01

The U.S. Department of Energy, Lockheed Martin Space Systems Company, Sunpower Inc., and NASA Glenn Research Center (GRC) have been developing an Advanced Stirling Radioisotope Generator (ASRG) for use as a power system on space science missions. This generator will make use of free-piston Stirling convertors to achieve higher conversion efficiency than with currently available alternatives. One part of NASA GRC's support of ASRG development includes extended operation testing of Advanced Stirling Convertors (ASCs) developed by Sunpower Inc. and GRC. The ASC consists of a free-piston Stirling engine integrated with a linear alternator. NASA GRC has been building test facilities to support extended operation of the ASCs for several years. Operation of the convertors in the test facility provides convertor performance data over an extended period of time. One part of the test facility is the test rack, which provides a means for data collection, convertor control, and safe operation. Over the years, the test rack requirements have changed. The initial ASC test rack utilized an alternating-current (AC) bus for convertor control; the ASRG Engineering Unit (EU) test rack can operate with AC bus control or with an ASC Control Unit (ACU). A new test rack is being developed to support extended operation of the ASC-E2s with higher standards of documentation, component selection, and assembly practices. This paper discusses the differences among the ASC, ASRG EU, and ASC-E2 test racks.

CFD Model of Water Droplet Transport for ISS Hygiene Activity

NASA Technical Reports Server (NTRS)

Son, Chang H.

2011-01-01

The goal of the study is to assess the impacts of free water propagation in the Waste and Hygiene Compartment (WHC). Free water can be generated inside the WHC in small quantities due to crew hygiene activity. To mitigate potential impact of free water in Node 3 cabin the WHC doorway is enclosed by a waterproof bump-out, Kabin, with openings at the top and bottom. At the overhead side of the rack, there is a screen that prevents large drops of water from exiting. However, as the avionics fan in the WHC causes airflow toward the deck side of the rack, small quantities of free water may exit at the bottom of the Kabin. A Computational Fluid Dynamics (CFD) analysis of Node 3 cabin airflow made possible to identify the paths of water transport. The Node 3 airflow was computed for several ventilation scenarios. To simulate the droplet transport the Lagrangian discrete phase approach was used. Various initial droplet distributions were considered in the study. The droplet diameter was varied in the range of 2-20 mm. The results of the computations showed that most of the drops fall to the rack surface not far from the WHC curtain. The probability of the droplet transport to the adjacent rack surface with electronic equipment was predicted.

The placement of equipment in the Space Station Freedom using constraint based reasoning

NASA Technical Reports Server (NTRS)

Tanner, Steve; Fennel, Randy

1991-01-01

This paper describes the Rack Equipment Placement and Optimization System. The primary objective of this system is to assist engineers with the placement of equipment into the racks of the modules of Space Station Freedom. It accomplishes this by showing a user where equipment placement is possible and by generating potential layouts. The system uses an explicit representation of integration constraints to search for potential solutions for individual rack equipment items. A simulated annealing process is being evaluated for total solution generation as well. Versions of this system are in use now and are assisting with the development of the Space Station Freedom at the Marshall Space Flight Center in Huntsville, Alabama.

Declic: design, integration and testing of a multi configurable instrument using optical diagnostics to study directional solidification and critical fluids

NASA Astrophysics Data System (ADS)

Durieux, A.; Martin, B.; Laubier, D.

2017-11-01

DECLIC, a Facility dedicated to the study of transparent media under microgravity, will be used in an ISS EXPRESS Rack. This paper focuses on the EXL which contains two optical boxes disposed on two opposite sides of the cavity where the Inserts to be studied shall be locked. At the moment, three types of inserts are planned to be accommodated in the EXL. Various optical diagnostics are available by configuring the EXL (sources, sensors, mechanisms). After the presentation of the EXL design, this article deals with some manufacturing and testing aspects, such as the use of COTS (cameras). Specific OGSE have been developed in order to simulate the optical interfaces and the propagation of beams in the inserts. Three models of the EXL have been integrated and fully tested, including the Flight Model. The sequence of tests, the performances measured, and then some images of the experiments performed with the inserts will be presented.

Power Systems Integration Laboratory | Energy Systems Integration Facility

Science.gov Websites

inverters. Key Infrastructure Grid simulator, load bank, Opal-RT, battery, inverter mounting racks, data , frequency-watt, and grid anomaly ride-through. Key Infrastructure House power, Opal-RT, PV simulator access

Integrating Bicycles and Transit in Santa Barbara, California

DOT National Transportation Integrated Search

1983-03-01

The integration of bicycles and transit in Santa Barbara, California, was designed as an innovative demonstration project, to increase local transit ridership. The Santa Barbara Metropolitan Transit District (SBMTD) installed bicycle racks and locker...

Reusable Rack Interface Controller Common Software for Various Science Research Racks on the International Space Station

NASA Technical Reports Server (NTRS)

Lu, George C.

2003-01-01

The purpose of the EXPRESS (Expedite the PRocessing of Experiments to Space Station) rack project is to provide a set of predefined interfaces for scientific payloads which allow rapid integration into a payload rack on International Space Station (ISS). VxWorks' was selected as the operating system for the rack and payload resource controller, primarily based on the proliferation of VME (Versa Module Eurocard) products. These products provide needed flexibility for future hardware upgrades to meet everchanging science research rack configuration requirements. On the International Space Station, there are multiple science research rack configurations, including: 1) Human Research Facility (HRF); 2) EXPRESS ARIS (Active Rack Isolation System); 3) WORF (Window Observational Research Facility); and 4) HHR (Habitat Holding Rack). The RIC (Rack Interface Controller) connects payloads to the ISS bus architecture for data transfer between the payload and ground control. The RIC is a general purpose embedded computer which supports multiple communication protocols, including fiber optic communication buses, Ethernet buses, EIA-422, Mil-Std-1553 buses, SMPTE (Society Motion Picture Television Engineers)-170M video, and audio interfaces to payloads and the ISS. As a cost saving and software reliability strategy, the Boeing Payload Software Organization developed reusable common software where appropriate. These reusable modules included a set of low-level driver software interfaces to 1553B. RS232, RS422, Ethernet buses, HRDL (High Rate Data Link), video switch functionality, telemetry processing, and executive software hosted on the FUC computer. These drivers formed the basis for software development of the HRF, EXPRESS, EXPRESS ARIS, WORF, and HHR RIC executable modules. The reusable RIC common software has provided extensive benefits, including: 1) Significant reduction in development flow time; 2) Minimal rework and maintenance; 3) Improved reliability; and 4) Overall reduction in software life cycle cost. Due to the limited number of crew hours available on ISS for science research, operational efficiency is a critical customer concern. The current method of upgrading RIC software is a time consuming process; thus, an improved methodology for uploading RIC software is currently under evaluation.

A fully automated liquid–liquid extraction system utilizing interface detection

PubMed Central

Maslana, Eugene; Schmitt, Robert; Pan, Jeffrey

2000-01-01

The development of the Abbott Liquid-Liquid Extraction Station was a result of the need for an automated system to perform aqueous extraction on large sets of newly synthesized organic compounds used for drug discovery. The system utilizes a cylindrical laboratory robot to shuttle sample vials between two loading racks, two identical extraction stations, and a centrifuge. Extraction is performed by detecting the phase interface (by difference in refractive index) of the moving column of fluid drawn from the bottom of each vial containing a biphasic mixture. The integration of interface detection with fluid extraction maximizes sample throughput. Abbott-developed electronics process the detector signals. Sample mixing is performed by high-speed solvent injection. Centrifuging of the samples reduces interface emulsions. Operating software permits the user to program wash protocols with any one of six solvents per wash cycle with as many cycle repeats as necessary. Station capacity is eighty, 15 ml vials. This system has proven successful with a broad spectrum of both ethyl acetate and methylene chloride based chemistries. The development and characterization of this automated extraction system will be presented. PMID:18924693

The interaction of protein-tyrosine phosphatase α (PTPα) and RACK1 protein enables insulin-like growth factor 1 (IGF-1)-stimulated Abl-dependent and -independent tyrosine phosphorylation of PTPα.

PubMed

Khanna, Ranvikram S; Le, Hoa T; Wang, Jing; Fung, Thomas C H; Pallen, Catherine J

2015-04-10

Protein tyrosine phosphatase α (PTPα) promotes integrin-stimulated cell migration in part through the role of Src-phosphorylated PTPα-Tyr(P)-789 in recruiting and localizing p130Cas to focal adhesions. The growth factor IGF-1 also stimulates PTPα-Tyr-789 phosphorylation to positively regulate cell movement. This is in contrast to integrin-induced PTPα phosphorylation, that induced by IGF-1 can occur in cells lacking Src family kinases (SFKs), indicating that an unknown kinase distinct from SFKs can target PTPα. We show that this IGF-1-stimulated tyrosine kinase is Abl. We found that PTPα binds to the scaffold protein RACK1 and that RACK1 coordinates the IGF-1 receptor, PTPα, and Abl in a complex to enable IGF-1-stimulated and Abl-dependent PTPα-Tyr-789 phosphorylation. In cells expressing SFKs, IGF-1-stimulated phosphorylation of PTPα is mediated by RACK1 but is Abl-independent. Furthermore, expressing the SFKs Src and Fyn in SFK-deficient cells switches IGF-1-induced PTPα phosphorylation to occur in an Abl-independent manner, suggesting that SFK activity dominantly regulates IGF-1/IGF-1 receptor signaling to PTPα. RACK1 is a molecular scaffold that integrates growth factor and integrin signaling, and our identification of PTPα as a RACK1 binding protein suggests that RACK1 may coordinate PTPα-Tyr-789 phosphorylation in these signaling networks to promote cell migration. © 2015 by The American Society for Biochemistry and Molecular Biology, Inc.

Lessons Learned "Establishing an Electrically Safe Work Condition" Specifically related to Racking Electrical Breakers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Martinez, Tommy Robert; Romero, Philbert Roland; Garcia, Samuel Anthony

During low voltage electrical equipment maintenance, a bad breaker was identified. The breaker was racked out from the substation cubicle without following the hazardous energy control process identified in the Integrated Work Document (IWD). The IWD required the substation to be in an electrically safe work condition prior to racking the breaker. Per NFPA 70E requirements, electrical equipment shall be put into an electrically safe work condition before an employee performs work on or interacts with equipment in a manner that increases the likelihood of creating an arc flash. Racking in or out a breaker on an energized bus maymore » increase the likelihood of creating an arc flash dependent on equipment conditions. A thorough risk assessment must be performed prior to performing such a task. The risk assessment determines the risk control measures to be put in place prior to performing the work. Electrical Safety Officers (ESO) can assist in performing risk assessments and incorporating risk control measures.« less

International Space Station Research: Accomplishments and Pathways for Exploration and Fundamental Research

NASA Technical Reports Server (NTRS)

Robinson, Julie A.

2007-01-01

Beginning with the launch of the European Columbus module planned for December 2007, we approach a transition in the assembly of the International Space Station (ISS) that is of great importance for the sciences. During the following 18 months, we will operate the first experiments in Columbus physical science resource facilities and also launch and commission the Japanese Kibo module. In addition, two Multi-purpose Logistics Module (MPLM) flights will deliver the U.S. Combustion Integrated Rack (CIR) and Fluids Integrated Rack (FIR) along with their first science experiments. These facilities provide significant new capabilities for basic and applied physical science research in microgravity. New life support technologies will come online throughout 2008, and we will reach the milestone of a 6-person crew planned for April 2009. A larger crew enables significant more scientific use of all the facilities for the life of ISS. Planning for the use of the International Space Station as a national laboratory is also maturing as we near the completion of assembly, enabling access to ISS as a research platform for other government agencies and the private sector. The latest updates on National Laboratory implementation will also be provided in this presentation. At the same time as these significant increases in scientific capability, there have been significant ongoing accomplishments in NASA's early ISS research both exploration related and fundamental research. These accomplishments will be reviewed in context as harbingers of the capabilities of the International Space Station when assembly is complete. The Vision for Space Exploration serves to focus NASA's applied investigations in the physical sciences. However, the broader capability of the space station as a National Laboratory and as a nexus for international collaboration will also influence the study of gravity-dependent processes by researchers around the world.

Multipurpose Logistics Module, Leonardo, Rests in Discovery's Payload Bay

NASA Technical Reports Server (NTRS)

2001-01-01

This in-orbit close up shows the Italian Space Agency-built multipurpose Logistics Module (MPLM), Leonardo, the primary cargo of the STS-102 mission, resting in the payload bay of the Space Shuttle Orbiter Discovery. The Leonardo MPLM is the first of three such pressurized modules that will serve as the International Space Station's (ISS') moving vans, carrying laboratory racks filled with equipment, experiments, and supplies to and from the Station aboard the Space Shuttle. The cylindrical module is approximately 21-feet long and 15- feet in diameter, weighing almost 4.5 tons. It can carry up to 10 tons of cargo in 16 standard Space Station equipment racks. Of the 16 racks the module can carry, 5 can be furnished with power, data, and fluid to support refrigerators or freezers. In order to function as an attached station module as well as a cargo transport, the logistics module also includes components that provide life support, fire detection and suppression, electrical distribution, and computer functions. The eighth station assembly flight and NASA's 103rd overall flight, STS-102 launched March 8, 2001 for an almost 13 day mission.

International Space Station (ISS)

NASA Image and Video Library

2001-03-10

This in-orbit close up shows the Italian Space Agency-built multipurpose Logistics Module (MPLM), Leonardo, the primary cargo of the STS-102 mission, resting in the payload bay of the Space Shuttle Orbiter Discovery. The Leonardo MPLM is the first of three such pressurized modules that will serve as the International Space Station's (ISS') moving vans, carrying laboratory racks filled with equipment, experiments, and supplies to and from the Station aboard the Space Shuttle. The cylindrical module is approximately 21-feet long and 15- feet in diameter, weighing almost 4.5 tons. It can carry up to 10 tons of cargo in 16 standard Space Station equipment racks. Of the 16 racks the module can carry, 5 can be furnished with power, data, and fluid to support refrigerators or freezers. In order to function as an attached station module as well as a cargo transport, the logistics module also includes components that provide life support, fire detection and suppression, electrical distribution, and computer functions. The eighth station assembly flight and NASA's 103rd overall flight, STS-102 launched March 8, 2001 for an almost 13 day mission.

Status of the International Space Station Regenerative ECLSS Water Recovery and Oxygen Generation Systems

NASA Technical Reports Server (NTRS)

Bagdigian, Robert M.; Cloud, Dale

2005-01-01

NASA is developing three racks containing regenerative water recovery and oxygen generation systems (WRS and OGS) for deployment on the International Space Station (ISS). The major assemblies included in these racks are the Water Processor Assembly (WPA), Urine Processor Assembly (UPA), Oxygen Generation Assembly (OGA), and the Power Supply Module (PSM) supporting the OGA. The WPA and OGA are provided by Hamilton Sundstrand Space Systems International (HSSSI), Inc., while the UPA and PSM are developed in- house by the Marshall Space Flight Center (MSFC). The assemblies have completed the manufacturing phase and are in various stages of testing and integration into the flight racks. This paper summarizes the status as of April 2005 and describes some of the technical challenges encountered and lessons learned over the past year.

International Microgravity Plasma Facility IMPF: A Multi-User Modular Research Facility for Complex Plasma Research on ISS

NASA Astrophysics Data System (ADS)

Seurig, R.; Burfeindt, J.; Castegini, R.; Griethe, W.; Hofmann, P.

2002-01-01

On March 03, 2001, the PKE-Nefedov plasma experiment was successfully put into operation on board ISS. This complex plasma experiment is the predecessor for the semi-autonomous multi-user facility IMPF (International Microgravity Plasma Facility) to be flown in 2006 with an expected operational lifetime of 10 years. IMPF is envisioned to be an international research facility for investigators in the field of multi-component plasmas containing ions, electrons, and charged microparticles. This research filed is often referred to as "complex plasmas". The actual location of IMPF on ISS is not decided yet; potential infrastructure under consideration are EXPRESS Rack, Standard Interface Rack SIR, European Drawer Rack EDR, or a to be designed custom rack infrastructure on the Russian Segment. The actual development status of the DLR funded Pre-phase B Study for IMPF will be presented. For this phase, IMPF was assumed to be integrated in an EXPRESS Rack requiring four middeck lockers with two 4-PU ISIS drawers for accommodation. Technical and operational challenges, like a 240 Mbytes/sec continuous experimental data stream for 60 minutes, will be addressed. The project was funded by the German Space Agency (DLR) and was performed in close cooperation with scientists from the Max-Planck-Institute for Extraterrestical Physics in Munich, Germany.

Microgravity

NASA Image and Video Library

2000-01-31

Students from Albuquerque, MN, tour through the mockup of the U.S. Destiny laboratory module that will be attached to the International Space Station (ISS). Behind them are the racks for the Fluids and Combustion Facility being developed by Glenn Research Center. The mockup was on display at the Space Tehnology International Forum in Albuquerque, MN. Photo credit: NASA/Marshall Space Flight Center

Mold bolt and means for achieving close tolerances between bolts and bolt holes

NASA Technical Reports Server (NTRS)

Johnston, David L. (Inventor); Bryant, Phillip G. (Inventor)

1993-01-01

In the space shuttle, a cargo bay storage rack was required which was to be manufactured from a metal-plastic composite and bolted to a cargo structure. Following completion, utilization of the rack was disallowed due to tolerances, that is, the size differences between the outside bolt diameter and the inside hole diameter. In addition to the space shuttle problem there are other close tolerance requirements for bolts. Such environments often benefit from close tolerance bolting. Frequently such fabrication is not cost effective. Consequently there is a need for means of achieving close tolerances between bolts and bolt holes. Such means are provided. After compressing the elements together a strong rigid plastic, ceramic, or ceramic plastic fluid is forced into a channel extending through the bolt.

Status of the Node 3 Regenerative Environmental Cpntrol& Life Support System Water Recovery & Oxygen Generation Systems

NASA Technical Reports Server (NTRS)

Carrasquillo, Robyn L.

2003-01-01

NASA s Marshall Space Flight Center is providing three racks containing regenerative water recovery and oxygen generation systems (WRS and OGS) for flight on the lnternational Space Station s (ISS) Node 3 element. The major assemblies included in these racks are the Water Processor Assembly (WPA), Urine Processor Assembly (UPA), Oxygen Generation Assembly (OGA), and the Power Supply Module (PSM) supporting the OGA. The WPA and OGA are provided by Hamilton Sundstrand Space Systems lnternational (HSSSI), while the UPA and PSM are being designed and manufactured in-house by MSFC. The assemblies are currently in the manufacturing and test phase and are to be completed and integrated into flight racks this year. This paper gives an overview of the technologies and system designs, technical challenges encountered and solved, and the current status.

STS-102 Onboard Photograph-Multi-Purpose Logistics Module, Leonardo

NASA Technical Reports Server (NTRS)

2001-01-01

A crewmember of Expedition One, cosmonaut Yuri P. Gidzenko, is dwarfed by transient hardware aboard Leonardo, the Italian Space Agency-built Multi-Purpose Logistics Module (MPLM), a primary cargo of the STS-102 mission. The Leonardo MPLM is the first of three such pressurized modules that will serve as the International Space Station's (ISS's) moving vans, carrying laboratory racks filled with equipment, experiments and supplies to and from the Space Station aboard the Space Shuttle. The cylindrical module is approximately 21-feet long and 15- feet in diameter, weighing almost 4.5 tons. It can carry up to 10 tons of cargo into 16 standard Space Station equipment racks. Of the 16 racks the module can carry, 5 can be furnished with power, data, and fluid to support refrigerators or freezers. In order to function as an attached station module as well as a cargo transport, the logistics module also includes components that provide life support, fire detection and suppression, electrical distribution, and computer functions. The eighth Shuttle mission to visit the ISS, the STS-102 mission served as a crew rotation flight. It delivered the Expedition Two crew to the Station and returned the Expedition One crew back to Earth.

International Space Station (ISS)

NASA Image and Video Library

2001-03-01

A crewmember of Expedition One, cosmonaut Yuri P. Gidzenko, is dwarfed by transient hardware aboard Leonardo, the Italian Space Agency-built Multi-Purpose Logistics Module (MPLM), a primary cargo of the STS-102 mission. The Leonardo MPLM is the first of three such pressurized modules that will serve as the International Space Station's (ISS's) moving vans, carrying laboratory racks filled with equipment, experiments and supplies to and from the Space Station aboard the Space Shuttle. The cylindrical module is approximately 21-feet long and 15- feet in diameter, weighing almost 4.5 tons. It can carry up to 10 tons of cargo into 16 standard Space Station equipment racks. Of the 16 racks the module can carry, 5 can be furnished with power, data, and fluid to support refrigerators or freezers. In order to function as an attached station module as well as a cargo transport, the logistics module also includes components that provide life support, fire detection and suppression, electrical distribution, and computer functions. The eighth Shuttle mission to visit the ISS, the STS-102 mission served as a crew rotation flight. It delivered the Expedition Two crew to the Station and returned the Expedition One crew back to Earth.

CFD Lagrangian Modeling of Water Droplet Transport for ISS Hygiene Activity Application

NASA Technical Reports Server (NTRS)

Son, Chang H.

2013-01-01

The goal of this study was to assess the impacts of free water propagation in the Waste and Hygiene Compartment (WHC) installed in Node 3. Free water can be generated inside the WHC in small quantities due to crew hygiene activity. To mitigate potential impact of free water in Node 3 cabin the WHC doorway is enclosed by a waterproof bump-out, Kabin, with openings at the top and bottom. At the overhead side of the rack, there is a screen that prevents large drops of water from exiting. However, as the avionics fan in the WHC causes airflow toward the deck side of the rack, small quantities of free water may exit at the bottom of the Kabin. A Computational Fluid Dynamics (CFD) analysis of Node 3 cabin airflow enable identifying the paths of water transport. To simulate the droplet transport the Lagrangian discrete phase approach was used. Various initial droplet distributions were considered in the study. The droplet diameter was varied in the range of 5-20 mm. The results of the computations showed that most of the drops fall to the rack surface not far from the WHC curtain.

KSC-01pp1426

NASA Image and Video Library

2001-08-06

KENNEDY SPACE CENTER, Fla. -- In the Space Station Processing Facility under the gaze of a worker (far right), the Expedition Three crew look over an Electronic Control Unit. From left are Commander Frank Culbertson and cosmonauts Mikhail Tyurin and Vladimir Dezhurov. The STS-105 mission payload includes the Early Ammonia Servicer (EAS), Multi-Purpose Logistics Module Leonardo and various experiments attached on the port and starboard adapter beams. The EAS contains spare ammonia for the Station’s cooling system. Ammonia is the fluid used in the radiators that cool the Station’s electronics. The EAS will be installed on the P6 truss holding the giant U.S. solar arrays, batteries and cooling radiators. Leonardo is filled with laboratory racks of science equipment and racks and platforms of experiments and supplies. Discovery is scheduled to be launched Aug. 9, 2001

KSC-01pp1427

NASA Image and Video Library

2001-08-06

KENNEDY SPACE CENTER, Fla. -- In the Space Station Processing Facility, the Expedition Three crew (right) listen to a worker discuss solar panels seen here on a workstand. The crew members are (left to right) Commander Frank Culbertson and cosmonauts Mikhail Tyurin and Vladimir Dezhurov. The STS-105 payload includes the Early Ammonia Servicer (EAS), Multi-Purpose Logistics Module Leonardo and various experiments attached on the port and starboard adapter beams. The EAS contains spare ammonia for the Station’s cooling system. Ammonia is the fluid used in the radiators that cool the Station’s electronics. The EAS will be installed on the P6 truss holding the giant U.S. solar arrays, batteries and cooling radiators. Leonardo is filled with laboratory racks of science equipment and racks and platforms of experiments and supplies. Discovery is scheduled to be launched Aug. 9, 2001

Random Access Frames (RAF): Alternative to Rack and Standoff for Deep Space Habitat Outfitting

NASA Technical Reports Server (NTRS)

Howe, A. Scott; Polit-Casillas, Raul

2014-01-01

A modular Random Access Frame (RAF) system is proposed as an alternative to the International Standard Payload Rack (ISPR) for internal module layout and outfitting in a Deep Space Habitat (DSH). The ISPR approach was designed to allow for efficient interchangeability of payload and experiments for the International Space Station (ISS) when frequent resupply missions were available (particularly the now-retired Space Shuttle). Though the standard interface approach to the ISPR system allowed integration of subsystems and hardware from a variety of sources and manufacturers, the heavy rack and standoff approach may not be appropriate when resupply or swap-out capabilities are not available, such as on deep space, long-duration missions. The lightweight RAF concept can allow a more dense packing of stowage and equipment, and may be easily broken down for repurposing or reuse. Several example layouts and workstations are presented.

CIR Combustion Chamber Fuel Reservoir Ops

NASA Image and Video Library

2009-09-26

ISS020-E-042198 (26 Sept. 2009) --- NASA astronaut Nicole Stott, Expedition 20 flight engineer, works with the Combustion Integrated Rack (CIR) in the Destiny laboratory of the International Space Station.

CIR Combustion Chamber Fuel Reservoir Ops

NASA Image and Video Library

2009-09-26

ISS020-E-042207 (26 Sept. 2009) --- NASA astronaut Nicole Stott, Expedition 20 flight engineer, works with the Combustion Integrated Rack (CIR) in the Destiny laboratory of the International Space Station.

CIR Combustion Chamber Fuel Reservoir Ops

NASA Image and Video Library

2009-09-26

ISS020-E-042203 (26 Sept. 2009) --- NASA astronaut Nicole Stott, Expedition 20 flight engineer, works with the Combustion Integrated Rack (CIR) in the Destiny laboratory of the International Space Station.

Plasmonic rack-and-pinion gear with chiral metasurface

NASA Astrophysics Data System (ADS)

Gorodetski, Yuri; Karabchevsky, Alina

2016-04-01

The effect of circularly polarized beaming excited by traveling surface plasmons, via chiral metasurface is experimentally studied. Here we show that the propagation direction of the plasmonic wave, evanescently excited on the thin gold film affects the handedness of the scattered beam polarization. Nanostructured metasurface leads to excitation of localized plasmonic modes whose relative spatial orientation induces overall spin-orbit interaction. This effect is analogical to the rack-and-pinion gear: the rotational motion into the linear motion converter. From the practical point of view, the observed effect can be utilized in integrated optical circuits for communication systems, cyber security and sensing.

Asetek's Warm-Water Liquid Cooling System Yields Energy Cost Savings at

Science.gov Websites

NREL | Energy Systems Integration Facility | NREL Asetek Asetek's Warm-Water Liquid Cooling System Yields Energy Cost Savings at NREL Asetek's RackCDU liquid cooling system was installed and tested at the Energy Systems Integration Facility's (ESIF's) ultra-energy-efficient high-performance

Gradient Heating Facility in the Materials Science Double Rack (MSDR) on Spacelab-1 Module

NASA Technical Reports Server (NTRS)

1983-01-01

The Space Shuttle was designed to carry large payloads into Earth orbit. One of the most important payloads is Spacelab. The Spacelab serves as a small but well-equipped laboratory in space to perform experiments in zero-gravity and make astronomical observations above the Earth's obscuring atmosphere. In this photograph, Payload Specialist, Ulf Merbold, is working at Gradient Heating Facility on the Materials Science Double Rack (MSDR) inside the science module in the Orbiter Columbia's payload bay during STS-9, Spacelab-1 mission. Spacelab-1, the joint ESA (European Space Agency)/NASA mission, was the first operational flight for the Spacelab, and demonstrated new instruments and methods for conducting experiments that are difficult or impossible in ground-based laboratories. This facility performed, in extremely low gravity, a wide variety of materials processing experiments in crystal growth, fluid physics, and metallurgy. The Marshall Space Flight Center had overall management responsibilities.

STS-102 Onboard Photograph Inside Multipurpose Logistics Module, Leonardo

NASA Technical Reports Server (NTRS)

2001-01-01

Pilot James M. Kelly (left) and Commander James D. Wetherbee for the STS-102 mission, participate in the movement of supplies inside Leonardo, the Italian Space Agency built Multipurpose Logistics Module (MPLM). In this particular photograph, the two are handling a film magazine for the IMAX cargo bay camera. The primary cargo of the STS-102 mission, the Leonardo MPLM is the first of three such pressurized modules that will serve as the International Space Station's (ISS') moving vans, carrying laboratory racks filled with equipment, experiments, and supplies to and from the Station aboard the Space Shuttle. The cylindrical module is approximately 21-feet long and 15- feet in diameter, weighing almost 4.5 tons. It can carry up to 10 tons of cargo in 16 standard Space Station equipment racks. Of the 16 racks the module can carry, 5 can be furnished with power, data, and fluid to support refrigerators or freezers. In order to function as an attached station module as well as a cargo transport, the logistics module also includes components that provide life support, fire detection and suppression, electrical distribution, and computer functions. The eighth station assembly flight, the STS-102 mission also served as a crew rotation flight. It delivered the Expedition Two crew to the Station and returned the Expedition One crew back to Earth.

International Space Station (ISS)

NASA Image and Video Library

2003-03-08

The Space Shuttle Discovery, STS-102 mission, clears launch pad 39B at the Kennedy Space Center as the sun peers over the Atlantic Ocean on March 8, 2001. STS-102's primary cargo was the Leonardo, the Italian Space Agency built Multipurpose Logistics Module (MPLM). The Leonardo MPLM is the first of three such pressurized modules that will serve as the International Space Station's (ISS') moving vans, carrying laboratory racks filled with equipment, experiments, and supplies to and from the Station aboard the Space Shuttle. The cylindrical module is approximately 21-feet long and 15- feet in diameter, weighing almost 4.5 tons. It can carry up to 10 tons of cargo in 16 standard Space Station equipment racks. Of the 16 racks the module can carry, 5 can be furnished with power, data, and fluid to support refrigerators or freezers. In order to function as an attached station module as well as a cargo transport, the logistics module also includes components that provide life support, fire detection and suppression, electrical distribution, and computer functions. NASA's 103rd overall flight and the eighth assembly flight, STS-102 was also the first flight involved with Expedition Crew rotation. The Expedition Two crew was delivered to the station while Expedition One was returned home to Earth.

International Space Station (ISS)

NASA Image and Video Library

2001-03-01

Pilot James M. Kelly (left) and Commander James D. Wetherbee for the STS-102 mission, participate in the movement of supplies inside Leonardo, the Italian Space Agency built Multipurpose Logistics Module (MPLM). In this particular photograph, the two are handling a film magazine for the IMAX cargo bay camera. The primary cargo of the STS-102 mission, the Leonardo MPLM is the first of three such pressurized modules that will serve as the International Space Station's (ISS') moving vans, carrying laboratory racks filled with equipment, experiments, and supplies to and from the Station aboard the Space Shuttle. The cylindrical module is approximately 21-feet long and 15- feet in diameter, weighing almost 4.5 tons. It can carry up to 10 tons of cargo in 16 standard Space Station equipment racks. Of the 16 racks the module can carry, 5 can be furnished with power, data, and fluid to support refrigerators or freezers. In order to function as an attached station module as well as a cargo transport, the logistics module also includes components that provide life support, fire detection and suppression, electrical distribution, and computer functions. The eighth station assembly flight, the STS-102 mission also served as a crew rotation flight. It delivered the Expedition Two crew to the Station and returned the Expedition One crew back to Earth.

International Space Station (ISS)

NASA Image and Video Library

2001-03-08

STS-102 astronaut and mission specialist, Andrew S.W. Thomas, gazes through an aft window of the Space Shuttle Orbiter Discovery as it approaches the docking bay of the International Space Station (ISS). Launched March 8, 2001, STS-102's primary cargo was the Leonardo, the Italian Space Agency-built Multipurpose Logistics Module (MPLM). The Leonardo MPLM is the first of three such pressurized modules that will serve as the ISS's moving vans, carrying laboratory racks filled with equipment, experiments, and supplies to and from the Station aboard the Space Shuttle. The cylindrical module is approximately 21-feet long and 15- feet in diameter, weighing almost 4.5 tons. It can carry up to 10 tons of cargo in 16 standard Space Station equipment racks. Of the 16 racks the module can carry, 5 can be furnished with power, data, and fluid to support refrigerators or freezers. In order to function as an attached station module as well as a cargo transport, the logistics module also includes components that provide life support, fire detection and suppression, electrical distribution, and computer functions. NASA's 103rd overall mission and the 8th Space Station Assembly Flight, STS-102 mission also served as a crew rotation flight. It delivered the Expedition Two crew to the Station and returned the Expedition One crew back to Earth.

Arabidopsis Receptor of Activated C Kinase1 Phosphorylation by WITH NO LYSINE8 KINASE

DOE PAGES

Urano, Daisuke; Czarnecki, Olaf; Wang, Xiaoping; ...

2014-12-08

Receptor of activated C kinase1 (RACK1) is a versatile scaffold protein that binds to numerous proteins to regulate diverse cellular pathways in mammals. In Arabidopsis (Arabidopsis thaliana), RACK1 has been shown to regulate plant hormone signaling, stress responses, and multiple processes of growth and development. However, little is known about the molecular mechanism underlying these regulations. In this paper, we show that an atypical serine (Ser)/threonine (Thr) protein kinase, WITH NO LYSINE8 (WNK8), phosphorylates RACK1. WNK8 physically interacted with and phosphorylated RACK1 proteins at two residues: Ser-122 and Thr-162. Genetic epistasis analysis of rack1 wnk8 double mutants indicated that RACK1more » acts downstream of WNK8 in the glucose responsiveness and flowering pathways. The phosphorylation-dead form, RACK1AS122A/T162A, but not the phosphomimetic form, RACK1AS122D/T162E, rescued the rack1a null mutant, implying that phosphorylation at Ser-122 and Thr-162 negatively regulates RACK1A function. The transcript of RACK1AS122D/T162E accumulated at similar levels as those of RACK1S122A/T162A. However, although the steady-state level of the RACK1AS122A/T162A protein was similar to wild-type RACK1A protein, the RACK1AS122D/T162E protein was nearly undetectable, suggesting that phosphorylation affects the stability of RACK1A proteins. In conclusion, these results suggest that RACK1 is phosphorylated by WNK8 and that phosphorylation negatively regulates RACK1 function by influencing its protein stability.« less

Design Report Final - CUB Inc.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Armijo, Kenneth Miguel; Monda, Mark J.; Brunson, Gregory Paul

CUB (Critical Utility Base), Fig. 1.0, are individual portable energy and utility units utilizing renewable energy technologies integrated with high efficient conventional components to provide electricity, battery storage, heat, potable water, waste water treatment, cooling, liquid fuels, to name some of the primary utilities. Typically, these units were designed to provide power / utilities to any remote location or facility like forward operating bases, disaster relief centers, and Native American communities or to energize African villages. Although some CUB models have already been designed to date, the main unit, the CUB-E (electricity), lacks a critical component included in its design.more » It is the integral portion that automates solar electric panel racking deployment and retraction. This racking system will enable the CUB-E to rapidly deploy its utility within minutes, a feature not available in any form currently on the market.« less

An open-source laser electronics suite

NASA Astrophysics Data System (ADS)

Pisenti, Neal C.; Reschovsky, Benjamin J.; Barker, Daniel S.; Restelli, Alessandro; Campbell, Gretchen K.

2016-05-01

We present an integrated set of open-source electronics for controlling external-cavity diode lasers and other instruments in the laboratory. The complete package includes a low-noise circuit for driving high-voltage piezoelectric actuators, an ultra-stable current controller based on the design of, and a high-performance, multi-channel temperature controller capable of driving thermo-electric coolers or resistive heaters. Each circuit (with the exception of the temperature controller) is designed to fit in a Eurocard rack equipped with a low-noise linear power supply capable of driving up to 5 A at +/- 15 V. A custom backplane allows signals to be shared between modules, and a digital communication bus makes the entire rack addressable by external control software over TCP/IP. The modular architecture makes it easy for additional circuits to be designed and integrated with existing electronics, providing a low-cost, customizable alternative to commercial systems without sacrificing performance.

The Multi-User Droplet Combustion Apparatus: the Development and Integration Concept for Droplet Combustion Payloads in the Fluids and Combustion Facility Combustion Integrated Rack

NASA Astrophysics Data System (ADS)

Myhre, C. A.

2002-01-01

The Multi-user Droplet Combustion Apparatus (MDCA) is a multi-user facility designed to accommodate four different droplet combustion science experiments. The MDCA will conduct experiments using the Combustion Integrated Rack (CIR) of the NASA Glenn Research Center's Fluids and Combustion Facility (FCF). The payload is planned for the International Space Station. The MDCA, in conjunction with the CIR, will allow for cost effective extended access to the microgravity environment, not possible on previous space flights. It is currently in the Engineering Model build phase with a planned flight launch with CIR in 2004. This paper provides an overview of the capabilities and development status of the MDCA. The MDCA contains the hardware and software required to conduct unique droplet combustion experiments in space. It consists of a Chamber Insert Assembly, an Avionics Package, and a multiple array of diagnostics. Its modular approach permits on-orbit changes for accommodating different fuels, fuel flow rates, soot sampling mechanisms, and varying droplet support and translation mechanisms to accommodate multiple investigations. Unique diagnostic measurement capabilities for each investigation are also provided. Additional hardware provided by the CIR facility includes the structural support, a combustion chamber, utilities for the avionics and diagnostic packages, and the fuel mixing capability for PI specific combustion chamber environments. Common diagnostics provided by the CIR will also be utilized by the MDCA. Single combustible fuel droplets of varying sizes, freely deployed or supported by a tether are planned for study using the MDCA. Such research supports how liquid-fuel-droplets ignite, spread, and extinguish under quiescent microgravity conditions. This understanding will help us develop more efficient energy production and propulsion systems on Earth and in space, deal better with combustion generated pollution, and address fire hazards associated with using liquid combustibles on Earth and in space. As a result of the concurrent design process of MDCA and CIR, the MDCA team continues to work closely with the CIR team, developing Integration Agreements and an Interface Control Document during preliminary integration activities. Integrated testing of hardware and software systems will occur at the Engineering Model and Flight Model phases. Because the engineering model is a high fidelity unit, it will be upgraded to a flight equivalent Ground Integration Unit (GIU) when the engineering model phase is completed. The GIU will be available on the ground for troubleshooting of any on-orbit problems. Integrated verification testing will be conducted with the MDCA flight unit and the CIR flight unit. Upon successful testing, the MDCA will be shipped to the Kennedy Space Center for a post-shipment checkout and final turn-over to CIR for final processing and launch to the International Space Station. Once on-orbit, the MDCA is managed from the GRC Telescience Support Center (TSC). The MDCA operations team resides at the TSC. Data is transmitted to the PI's at their home sites by means of TREK workstations, allowing direct interaction between the PI and operations staff to maximum science. Upon completion of a PI's experiment, the MDCA is reconfigured for the next of the three follow-on experiments or ultimately removed from the CIR, placed into stowage, and returned to Earth.

Proposed Space Flight Experiment Hardware

NASA Technical Reports Server (NTRS)

2003-01-01

The primary thrust for this plan is to develop design tools and fundamental understanding that are timely and consistent with the goal of the various exploration initiatives. The plan will utilize ISS facilities, such as the Fluids Integrated Rack (FIR) and the Microgravity Science Glovebox (MSG). A preliminary flow schematic of Two-Phase Flow Facility (T(phi)FFy) which would utilize FIR is shown in Figure 3. MSG can be utilized to use the Boiling eXperiment Facility (BXF) and Contact Line Dynamics Experiment (CLiDE) Facility. The T(phi)FFy system would have multiple test sections whereby different configurations of heat exchangers could be used to study boiling and condensation phenomena. The test sections would be instrumented for pressure drop, void fraction, heat fluxes, temperatures, high-speed imaging and other diagnostics. Besides a high-speed data acquisition system with a large data storage capability, telemetry could be used to update control and test parameters and download limited amounts of data. In addition, there would be multiple accumulators that could be used to investigate system stability and fluid management issues. The system could accommodate adiabatic tests through either the space station nitrogen supply or have an experiment-specific compressor to pressurize a sufficient amount of air or other non-condensable gas for reuse as the supply bottle is depleted.

Physics of Colloids in Space: Microgravity Experiment Launched, Installed, and Activated on the International Space Station

NASA Technical Reports Server (NTRS)

Doherty, Michael P.

2002-01-01

The Physics of Colloids in Space (PCS) experiment is a Microgravity Fluids Physics investigation that is presently located in an Expedite the Process of Experiments to Space Station (EXPRESS) Rack on the International Space Station. PCS was launched to the International Space Station on April 19, 2001, activated on May 31, 2001, and will continue to operate about 90 hr per week through May 2002.

Tribology experiment. [journal bearings and liquid lubricants

NASA Technical Reports Server (NTRS)

Wall, W. A.

1981-01-01

A two-dimensional concept for Spacelab rack 7 was developed to study the interaction of liquid lubricants and surfaces under static and dynamic conditions in a low-gravity environment fluid wetting and spreading experiments of a journal bearing experiments, and means to accurately measure and record the low-gravity environment during experimentation are planned. The wetting and spreading process of selected commercial lubricants on representative surface are to the observes in a near-zero gravity environment.

A Selected Operational History of the Internal Thermal Control System (ITCS) for International Space Station (ISS)

NASA Technical Reports Server (NTRS)

Patel, Vipul P.; Winton, Dale; Ibarra, Thomas H.

2004-01-01

The Internal Thermal Control System (ITCS) has been developed jointly by Boeing Corporation, Huntsville, Alabama and Honeywell Engines & Systems, Torrance, California to meet the internal thermal control needs for the International Space Station (ISS). The ITCS provides heat removal for the critical life support systems and thermal conditioning for numerous experiment racks. The ITCS will be fitted on a number of modules on the ISS. The first US Element containing the ITCS, Node 1, was launched in December 1998. Since Node 1 does not contain a pump to circulate the fluid it was not filled with ITCS fluid until after the US Laboratory Module was installed. The second US Element module, US Laboratory Module, which contains the pumps and all the major ITCS control hardware, was launched in February 2001. The third US Element containing the ITCS, the US Airlock, was launched in July 2001. The dual loop system of the ITCS is comprised of a lowtemperature loop (LTL) and a moderate-temperature loop (MTL). Each loop has a pump package assembly (PPA), a system flow control assembly (SFCA), a threeway mixing valve (TWMV), several rack flow control assemblies (RFCA), cold plates, pressure sensors, temperature sensors, pump bypass assembly (PBA) and a heat exchanger. In addition, the MTL has an additional TWMV, a payload regeneration heat exchanger (P/RHE) and a manual flow control valve (MFCV). The LTL has a service performance and checkout unit (SPCU) heat exchanger. The two loops are linked via one loop crossover assembly (LCA) providing cross loop capabilities and a single PPA, two-loop functionality. One important parameter monitored by the ground stations and on-orbit is the amount of fluid leakage from the ITCS. ISS fluid leakage is of importance since ITCS fluid is costly to re-supply, may be difficult to clean up in zero-g, and if uncontained could lead to equipment failures and potential hazards. This paper examines the nominal leakage observed over period of a year of on-orbit operation and compares this with analysis predictions. This paper also addresses the off-nominal leakage and a fluid transfer event causing significant changes in accumulator quantity.

Do-It-Yourself Device for Recovery of Cryopreserved Samples Accidentally Dropped into Cryogenic Storage Tanks

PubMed Central

Mehta, Rohini; Baranova, Ancha; Birerdinc, Aybike

2012-01-01

Liquid nitrogen is colorless, odorless, extremely cold (-196 °C) liquid kept under pressure. It is commonly used as a cryogenic fluid for long term storage of biological materials such as blood, cells and tissues 1,2. The cryogenic nature of liquid nitrogen, while ideal for sample preservation, can cause rapid freezing of live tissues on contact - known as 'cryogenic burn'2, which may lead to severe frostbite in persons closely involved in storage and retrieval of samples from Dewars. Additionally, as liquid nitrogen evaporates it reduces the oxygen concentration in the air and might cause asphyxia, especially in confined spaces2. In laboratories, biological samples are often stored in cryovials or cryoboxes stacked in stainless steel racks within the Dewar tanks1. These storage racks are provided with a long shaft to prevent boxes from slipping out from the racks and into the bottom of Dewars during routine handling. All too often, however, boxes or vials with precious samples slip out and sink to the bottom of liquid nitrogen filled tank. In such cases, samples could be tediously retrieved after transferring the liquid nitrogen into a spare container or discarding it. The boxes and vials can then be relatively safely recovered from emptied Dewar. However, the cryogenic nature of liquid nitrogen and its expansion rate makes sunken sample retrieval hazardous. It is commonly recommended by Safety Offices that sample retrieval be never carried out by a single person. Another alternative is to use commercially available cool grabbers or tongs to pull out the vials3. However, limited visibility within the dark liquid filled Dewars poses a major limitation in their use. In this article, we describe the construction of a Cryotolerant DIY retrieval device, which makes sample retrieval from Dewar containing cryogenic fluids both safe and easy. PMID:22617806

Do-It-Yourself device for recovery of cryopreserved samples accidentally dropped into cryogenic storage tanks.

PubMed

Mehta, Rohini; Baranova, Ancha; Birerdinc, Aybike

2012-05-11

Liquid nitrogen is colorless, odorless, extremely cold (-196 °C) liquid kept under pressure. It is commonly used as a cryogenic fluid for long term storage of biological materials such as blood, cells and tissues (1,2). The cryogenic nature of liquid nitrogen, while ideal for sample preservation, can cause rapid freezing of live tissues on contact - known as 'cryogenic burn' (2), which may lead to severe frostbite in persons closely involved in storage and retrieval of samples from Dewars. Additionally, as liquid nitrogen evaporates it reduces the oxygen concentration in the air and might cause asphyxia, especially in confined spaces (2). In laboratories, biological samples are often stored in cryovials or cryoboxes stacked in stainless steel racks within the Dewar tanks (1). These storage racks are provided with a long shaft to prevent boxes from slipping out from the racks and into the bottom of Dewars during routine handling. All too often, however, boxes or vials with precious samples slip out and sink to the bottom of liquid nitrogen filled tank. In such cases, samples could be tediously retrieved after transferring the liquid nitrogen into a spare container or discarding it. The boxes and vials can then be relatively safely recovered from emptied Dewar. However, the cryogenic nature of liquid nitrogen and its expansion rate makes sunken sample retrieval hazardous. It is commonly recommended by Safety Offices that sample retrieval be never carried out by a single person. Another alternative is to use commercially available cool grabbers or tongs to pull out the vials (3). However, limited visibility within the dark liquid filled Dewars poses a major limitation in their use. In this article, we describe the construction of a Cryotolerant DIY retrieval device, which makes sample retrieval from Dewar containing cryogenic fluids both safe and easy.

Can an off-the-rack orthotic stiletto alter pressure and comfort scores in the forefoot, arch and heel?

PubMed

Penny, Jeannette Østergaard; Speedtsberg, Merete Brink; Kallemose, Thomas; Bencke, Jesper

2018-03-16

The study sought to investigate whether an orthotic stiletto could modulate the pressure and comfort under the forefoot, arch and heel that stiletto wearers experience. Twenty-two women participated. We measured the peak pressure and pressure-time integral for orthotic stilettos with built-in metatarsal pad, heel cup and arch support; standard stilettos without inlays; and trainers. Comfort was recorded during 3 × 3 working days. The orthotic stiletto exhibited lower metatarsal head1 (MTH) and MTH2+3 and heel pressures than the standard stiletto (p < .01), and a long second metatarsal increased MTH2+3 pressure (p < .01). The comfort in the forefoot and heel was higher in the orthotic stiletto than in the standard one (p < .01), and comfort in the forefoot was correlated to the pressure-time integral of MTH2+3 (p = .03) and not peak pressure. Off-the-rack orthotic stilettos can notably reduce plantar pressures and improve forefoot and heel comfort during everyday use. Practitioner Summary: Off-the-rack orthotic stilettos with built-in metatarsal pad, arch support and heel caps can lower the pressure under the heel and forefoot in comparison with a standard stiletto and can improve comfort during everyday use. Having a long second metatarsal is a risk factor for increased forefoot pressure.

International Space Station USOS Waste and Hygiene Compartment Development

NASA Technical Reports Server (NTRS)

Link, Dwight E., Jr.; Broyan, James Lee, Jr.; Gelmis, Karen; Philistine, Cynthia; Balistreri, Steven

2007-01-01

The International Space Station (ISS) currently provides human waste collection and hygiene facilities in the Russian Segment Service Module (SM) which supports a three person crew. Additional hardware is planned for the United States Operational Segment (USOS) to support expansion of the crew to six person capability. The additional hardware will be integrated in an ISS standard equipment rack structure that was planned to be installed in the Node 3 element; however, the ISS Program Office recently directed implementation of the rack, or Waste and Hygiene Compartment (WHC), into the U.S. Laboratory element to provide early operational capability. In this configuration, preserved urine from the WHC waste collection system can be processed by the Urine Processor Assembly (UPA) in either the U.S. Lab or Node 3 to recover water for crew consumption or oxygen production. The human waste collection hardware is derived from the Service Module system and is provided by RSC-Energia. This paper describes the concepts, design, and integration of the WHC waste collection hardware into the USOS including integration with U.S. Lab and Node 3 systems.

Providing Campus Environmental Coherence by Landscaping.

ERIC Educational Resources Information Center

Pawsey, Maurice R.

1982-01-01

A landscaping approach aimed at integrating greatly contrasting building types and materials resulting from unplanned growth used these elements to create design continuity; paving, planting, landscape furniture, planting and lawn protection, signs, lights, placement of posters and notices, and bicycle racks. (MSE)

International Space Station (ISS)

NASA Image and Video Library

2001-03-11

STS-102 mission astronaut Susan J. Helms translates along the longerons of the Space Shuttle Discovery during the first of two space walks. During this walk, the Pressurized Mating Adapter 3 was prepared for repositioning from the Unity Module's Earth-facing berth to its port-side berth to make room for the Leonardo multipurpose Logistics Module (MPLM), supplied by the Italian Space Agency. The Leonardo MPLM is the first of three such pressurized modules that will serve as the International Space Station's (ISS') moving vans, carrying laboratory racks filled with equipment, experiments, and supplies to and from the Station aboard the Space Shuttle. The cylindrical module is approximately 21-feet long and 15- feet in diameter, weighing almost 4.5 tons. It can carry up to 10 tons of cargo in 16 standard Space Station equipment racks. Of the 16 racks the module can carry, 5 can be furnished with power, data, and fluid to support refrigerators or freezers. In order to function as an attached station module as well as a cargo transport, the logistics module also includes components that provide life support, fire detection and suppression, electrical distribution, and computer functions. NASA's 103rd overall mission and the 8th Space Station Assembly Flight, STS-102 mission also served as a crew rotation flight. It delivered the Expedition Two crew to the Station and returned the Expedition One crew back to Earth.

STS-102 Astronaut Susan Helms Participates in Space Walk

NASA Technical Reports Server (NTRS)

2001-01-01

STS-102 mission astronaut Susan J. Helms translates along the longerons of the Space Shuttle Discovery during the first of two space walks. During this walk, the Pressurized Mating Adapter 3 was prepared for repositioning from the Unity Module's Earth-facing berth to its port-side berth to make room for the Leonardo multipurpose Logistics Module (MPLM), supplied by the Italian Space Agency. The Leonardo MPLM is the first of three such pressurized modules that will serve as the International Space Station's (ISS') moving vans, carrying laboratory racks filled with equipment, experiments, and supplies to and from the Station aboard the Space Shuttle. The cylindrical module is approximately 21-feet long and 15- feet in diameter, weighing almost 4.5 tons. It can carry up to 10 tons of cargo in 16 standard Space Station equipment racks. Of the 16 racks the module can carry, 5 can be furnished with power, data, and fluid to support refrigerators or freezers. In order to function as an attached station module as well as a cargo transport, the logistics module also includes components that provide life support, fire detection and suppression, electrical distribution, and computer functions. NASA's 103rd overall mission and the 8th Space Station Assembly Flight, STS-102 mission also served as a crew rotation flight. It delivered the Expedition Two crew to the Station and returned the Expedition One crew back to Earth.

Space biology initiative program definition review. Trade study 6: Space Station Freedom/spacelab modules compatibility

NASA Technical Reports Server (NTRS)

Jackson, L. Neal; Crenshaw, John, Sr.; Davidson, William L.; Blacknall, Carolyn; Bilodeau, James W.; Stoval, J. Michael; Sutton, Terry

1989-01-01

The differences in rack requirements for Spacelab, the Shuttle Orbiter, and the United States (U.S.) laboratory module, European Space Agency (ESA) Columbus module, and the Japanese Experiment Module (JEM) of Space Station Freedom are identified. The feasibility of designing standardized mechanical, structural, electrical, data, video, thermal, and fluid interfaces to allow space flight hardware designed for use in the U.S. laboratory module to be used in other locations is assessed.

Lightweight, Rack-Mountable Composite Cold Plate/Shelves

NASA Technical Reports Server (NTRS)

Hurlbert, Kathryn M.; Ruemmele, Warren; Nguyen, Hai D.; Andish, Kambiz; McCalley, Sean

2004-01-01

Rack-mountable composite-material structural components that would serve as both shelves and cold plates for removing heat from electronic or other equipment mounted on the shelves have been proposed as lightweight alternatives to all-metal cold plate/shelves now in use. A proposed cold plate/shelf would include a highly thermally conductive face sheet containing oriented graphite fibers bonded to an aluminum honeycomb core, plus an extruded stainless-steel substructure containing optimized flow passages for a cooling fluid, and an inlet and outlet that could be connected to standard manifold sections. To maximize heat-transfer efficiency, the extruded stainless-steel substructure would be connected directly to the face sheet. On the basis of a tentative design, the proposed composite cold plate/shelf would weigh about 38 percent less than does an all-aluminum cold plate in use or planned for use in some spacecraft and possibly aircraft. Although weight is a primary consideration, the tentative design offers the additional benefit of reduction of thickness to half that of the all-aluminum version.

21 CFR 886.1750 - Skiascopic rack.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Skiascopic rack. 886.1750 Section 886.1750 Food... DEVICES OPHTHALMIC DEVICES Diagnostic Devices § 886.1750 Skiascopic rack. (a) Identification. A skiascopic rack is a device that is a rack and a set of attached ophthalmic lenses of various dioptric strengths...

40 CFR 63.421 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Administrator and any other person. Controlled loading rack, for the purposes of § 63.420, means a loading rack... heat air pollutants to combustion temperatures. Uncontrolled loading rack means a loading rack used to load gasoline cargo tanks that is not a controlled loading rack. Vapor-tight gasoline cargo tank means...

78 FR 63166 - Certain Kitchen Appliance Shelving and Racks From the People's Republic of China: Countervailing...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-23

... Shelving and Racks From the People's Republic of China: Countervailing Duty Administrative Review; 2011... order on certain kitchen appliance shelving and racks (kitchen racks) from the People's Republic of.... Scope of the Order This order covers shelving and racks for refrigerators, freezers, combined...

The interaction between RACK1 and WEE1 regulates the growth of gastric cancer cell line HGC27

PubMed Central

Liu, Chao; Ren, Lili; Wang, Yizhao; Liu, Yimeng; Xiao, Jianying

2017-01-01

Receptor of activated C Kinase 1 (RACK1) is an essential scaffold and anchoring protein, which serves an important role in multiple tumorigenesis signaling pathways. The present study aimed to investigate the expression of RACK1 in gastric cancer (GC), and its association with the occurrence and development of GC. In addition, the effect and mechanism of RACK1 overexpression on the growth, and proliferation of GC cells was examined. Firstly, the protein expression of RACK1 was detected in 70 cases of GC tissues and 30 cases of noncancerous tissues using immunohistochemical staining, and the association between clinical and pathological features of GC was analyzed. Secondly, the mRNA and protein expression of RACK1 was determined in the poorly-differentiated human gastric cancer cell line HGC27 and gastric epithelial cell line GES-1. The growth of HGC27 cells following the upregulation of RACK1 was detected using MTT method. Subsequently, the interaction and co-location between RACK1, and WEE1 homolog (S. pombe) (WEE1) in HGC27 cells was confirmed using co-immunoprecipitation and indirect immunofluorescence. The expression level of RACK1 in GC was significantly lower compared with that in pericarcinous tissues (P<0.05). The protein level of RACK1 expression correlated with tumor node metastasis stage, tumor differentiation and lymph node metastasis. The mRNA and protein levels of RACK1 in HGC27 cells were significantly reduced, and overexpressed RACK1 downregulated WEE1 protein expression, thus inhibiting the growth of HGC27 cells. Co-immunoprecipitation and immunofluorescence confirmed that RACK1, and WEE1 interacted and co-located in the cytoplasm of HGC27 cells. Therefore, the abnormal expression of RACK1 in GC tissues was identified to be involved in the occurrence and development of GC. Overexpression of RACK1 was able to inhibit the growth of HGC27 cells. The current study suggests that low expression of RACK1 is an important indicator of poor prognosis of GC. RACK1 and WEE1 interact to regulate the growth of HGC27 cells. PMID:29085480

Toward IVHM Prognostics

NASA Technical Reports Server (NTRS)

Walsh, Kevin; Venti, Mike

2007-01-01

This viewgraph presentation reviews the prognostics of Integrated Vehicle Health Management. The contents include: 1) Aircraft Operations-Today's way of doing business; 2) Prognostics; 3) NASA's instrumentation data-system rack; 4) Data mining for IVHM; 5) NASA GRC's C-MAPSS generic engine model; and 6) Concluding thoughts.

76 FR 62364 - Certain Kitchen Appliance Shelving and Racks From the People's Republic of China: Preliminary...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-07

... Shelving and Racks From the People's Republic of China: Preliminary Results of the Countervailing Duty... countervailable duty order on certain kitchen appliance shelving and racks (``Kitchen Racks'') from the People's... Kitchen Appliance Shelving and Racks From the People's Republic of China: Countervailing Duty Order, 74 FR...

40 CFR 63.422 - Standards: Loading racks.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 9 2010-07-01 2010-07-01 false Standards: Loading racks. 63.422....422 Standards: Loading racks. (a) Each owner or operator of loading racks at a bulk gasoline terminal... facility” used in § 60.502 of this chapter means the loading racks that load gasoline cargo tanks at the...

Noncontact rack-pinion-rack device as a differential vibration sensor.

PubMed

Miri, MirFaez; Nasiri, Mojtaba

2010-07-01

We study a nanoscale system composed of one corrugated cylinder (pinion) placed between two corrugated plates (racks). The pinion and racks have no mechanical contact, but are coupled via the lateral Casimir force-one of the most spectacular consequences of quantum fluctuations of the electromagnetic field. The noncontact design of the device could help with the noteworthy wear problem in nanoscale mechanical systems. We consider the case where both racks undergo harmonic lateral motion. We assume that the amplitude, frequency, and phase of one of the racks are known. We show that probing the pinion motion, one can determine the vibration characteristics of the other rack.

Characterization and Expression Analysis of Receptor for Activated C Kinase from Silk-producing Insect Antheraea pernyi.

PubMed

Zhu, Bao-Jian; Yu, Hao; Tian, Sen; Dai, Li-Shang; Sun, Yu; Liu, Chao-Liang

2016-01-01

The receptor for activated C kinase (RACK) is an important scaffold protein with regulatory functions in cells. However, its role in the immune response of Antheraea pernyi to pathogen challenge remains unclear. To investigate the biological functions of RACK in the wild silkworm A. pernyi, cloning was performed and the expression patterns of the RACK gene were analyzed. Sequence analysis revealed that the RACK gene was 1120 bp containing a 960-bp open reading frame. The deduced RACK protein sequence reveals the higher identity with its homologs from other insects. SDS-PAGE and western blot analysis demonstrated successful expression of a 36-kDa recombinant RACK protein in Escherichia coli. The titer of a rabbit-raised antibody against recombinant RACK protein was about 1: 20000, determined by ELISA. Real-time PCR analysis showed that RACK expression was higher in fat bodies than in other examined A. pernyi tissues. The expression of RACK mRNA in fat bodies of fifth larvae of A. pernyi was obviously induced after nucleopolyhedrovirus, E. coli or Beauveria bassiana challenge. However, the expression patterns of RACK were different in response to these pathogens. Our data suggest that RACK may play a role in the innate immune responses of A. pernyi.

Direct Interaction between Scaffolding Proteins RACK1 and 14-3-3ζ Regulates Brain-derived Neurotrophic Factor (BDNF) Transcription*

PubMed Central

Neasta, Jérémie; Kiely, Patrick A.; He, Dao-Yao; Adams, David R.; O'Connor, Rosemary; Ron, Dorit

2012-01-01

RACK1 is a scaffolding protein that spatially and temporally regulates numerous signaling cascades. We previously found that activation of the cAMP signaling pathway induces the translocation of RACK1 to the nucleus. We further showed that nuclear RACK1 is required to promote the transcription of the brain-derived neurotrophic factor (BDNF). Here, we set out to elucidate the mechanism underlying cAMP-dependent RACK1 nuclear translocation and BDNF transcription. We identified the scaffolding protein 14-3-3ζ as a direct binding partner of RACK1. Moreover, we found that 14-3-3ζ was necessary for the cAMP-dependent translocation of RACK1 to the nucleus. We further observed that the disruption of RACK1/14-3-3ζ interaction with a peptide derived from the RACK1/14-3-3ζ binding site or shRNA-mediated 14-3-3ζ knockdown inhibited cAMP induction of BDNF transcription. Together, these data reveal that the function of nuclear RACK1 is mediated through its interaction with 14-3-3ζ. As RACK1 and 14-3-3ζ are two multifunctional scaffolding proteins that coordinate a wide variety of signaling events, their interaction is likely to regulate other essential cellular functions. PMID:22069327

10 CFR 36.35 - Source rack protection.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 1 2010-01-01 2010-01-01 false Source rack protection. 36.35 Section 36.35 Energy NUCLEAR... Requirements for Irradiators § 36.35 Source rack protection. If the product to be irradiated moves on a product conveyor system, the source rack and the mechanism that moves the rack must be protected by a barrier or...

40 CFR 63.9075 - What definitions apply to this subpart?

Code of Federal Regulations, 2010 CFR

2010-07-01

... loading, into a tank truck, railcar, ship, or barge, of liquid HCl from a transfer (or loading) rack (as... (or loading) rack is the material that is loaded by the transfer (or loading) rack in the greatest.... Transfer (or loading) rack means the collection of loading arms and loading hoses, at a single loading rack...

CIR

NASA Image and Video Library

2014-06-11

ISS040-E-010496 (11 June 2014) --- NASA astronaut Steve Swanson, Expedition 40 commander, works with the Multi-user Drop Combustion Apparatus (MDCA) inside the Combustion Integrated Rack (CIR) in the Destiny laboratory of the International Space Station. The MDCA contains hardware and software to conduct unique droplet combustion experiments in space.

CIR

NASA Image and Video Library

2014-06-11

ISS040-E-010502 (11 June 2014) --- NASA astronaut Steve Swanson, Expedition 40 commander, works with the Multi-user Drop Combustion Apparatus (MDCA) inside the Combustion Integrated Rack (CIR) in the Destiny laboratory of the International Space Station. The MDCA contains hardware and software to conduct unique droplet combustion experiments in space.

Combustion Research Aboard the ISS Utilizing the Combustion Integrated Rack and Microgravity Science Glovebox

NASA Technical Reports Server (NTRS)

Sutliff, Thomas J.; Otero, Angel M.; Urban, David L.

2002-01-01

The Physical Sciences Research Program of NASA sponsors a broad suite of peer-reviewed research investigating fundamental combustion phenomena and applied combustion research topics. This research is performed through both ground-based and on-orbit research capabilities. The International Space Station (ISS) and two facilities, the Combustion Integrated Rack and the Microgravity Science Glovebox, are key elements in the execution of microgravity combustion flight research planned for the foreseeable future. This paper reviews the Microgravity Combustion Science research planned for the International Space Station implemented from 2003 through 2012. Examples of selected research topics, expected outcomes, and potential benefits will be provided. This paper also summarizes a multi-user hardware development approach, recapping the progress made in preparing these research hardware systems. Within the description of this approach, an operational strategy is presented that illustrates how utilization of constrained ISS resources may be maximized dynamically to increase science through design decisions made during hardware development.

Fabrication of Fresnel micro lens array in borosilicate glass by F2-laser ablation for glass interposer application

NASA Astrophysics Data System (ADS)

Brusberg, Lars; Neitz, Marcel; Schröder, Henning; Fricke-Begemann, Thomas; Ihlemann, Jürgen

2014-03-01

The future need for more bandwidth forces the development of optical transmission solutions for rack-to-rack, boardto- board and chip-to-chip interconnects. The goals are significant reduction of power consumption, highest density and potential for bandwidth scalability to overcome the limitations of the systems today with mostly copper based interconnects. For system integration the enabling of thin glass as a substrate material for electro-optical components with integrated micro-optics for efficient light coupling to integrated optical waveguides or fibers is becoming important. Our glass based packaging approach merges micro-system packaging and glass integrated optics. This kind of packaging consists of a thin glass substrate with integrated micro lenses providing a platform for photonic component assembly and optical fiber or waveguide interconnection. Thin glass is commercially available in panel and wafer size and characterizes excellent optical and high frequency properties. That makes it perfect for microsystem packaging. A suitable micro lens approach has to be comparable with different commercial glasses and withstand post-processing like soldering. A benefit of using laser ablated Fresnel lenses is the planar integration capability in the substrate for highest integration density. In the paper we introduce our glass based packaging concept and the Fresnel lens design for different scenarios like chip-to-fiber, chip-to-optical-printed-circuit-board coupling. Based on the design the Fresnel lenses were fabricated by using a 157 nm fluorine laser ablation system.

U.S. Rep. Dave Weldon outside the U.S. Lab Destiny in the SSPF.

NASA Technical Reports Server (NTRS)

1999-01-01

Standing in front of the U.S. Lab, named Destiny, U.S. Rep. Dave Weldon (left) thanks Thomas R. 'Randy' Galloway, with the Space Station Hardware Integration Office, for briefing him on the equipment inside the Lab. Weldon is on the House Science Committee and vice chairman of the Space and Aeronautics Subcommittee. Destiny is scheduled to be launched on Space Shuttle Endeavour in early 2000. It will become the centerpiece of scientific research on the ISS, with five equipment racks aboard to provide essential functions for station systems, including high data-rate communications, and to maintain the station's orientation using control gyroscopes launched earlier. Additional equipment and research racks will be installed in the laboratory on subsequent Shuttle flights.

Phosphorylation of RACK1 in plants

DOE PAGES

Chen, Jay -Gui

2015-08-31

Receptor for Activated C Kinase 1 (RACK1) is a versatile scaffold protein that interacts with a large, diverse group of proteins to regulate various signaling cascades. RACK1 has been shown to regulate hormonal signaling, stress responses and multiple processes of growth and development in plants. However, little is known about the molecular mechanism underlying these regulations. Recently, it has been demonstrated that Arabidopsis RACK1 is phosphorylated by an atypical serine/threonine protein kinase, WITH NO LYSINE 8 (WNK8). Furthermore, RACK1 phosphorylation by WNK8 negatively regulates RACK1 function by influencing its protein stability. In conclusion, these findings promote a new regulatory systemmore » in which the action of RACK1 is controlled by phosphorylation and subsequent protein degradation.« less

Effectiveness of Rack Sanitation Procedures for Elimination of Bacteria from Automatic Watering Manifolds.

PubMed

Costello, Terry; Watkins, Linda; Straign, Mike; Bean, William; Toth, Linda; Rehg, Jerold

1998-03-01

An important responsibility of animal care programs is to protect research animals from exposure to potentially pathogenic microorganisms. To validate the need for steam sterilization of rodent automatic watering racks, we evaluate the post-sanitation microbial contamination of experimentally inoculated racks and of racks that had been used to house conventional mice. We tested three sanitation protocols: rack-washer sanitation without manifold flush, sanitation that included manifold flush, and sanitation that included manifold flush followed by autoclaving. Rack sanitation, with or without manifold flush, did not reliably eliminate microbial flora from the lixits or manifold drainage water. A total of 43% of all non-autoclaved racks were positive for bacterial contamination after sanitation, and racks that had been used for conventional animal housing were more frequently positive than were experimentally inoculated racks (79% vs 18%). These data indicate that steam sterilization is necessary for eliminating bacteria from automatic watering systems. These observations are particularly important in light of increasing numbers of immune-impaired rodents that may be inadvertently and unnecessarily exposed to microbial pathogens via the automatic watering system.

International Space Station (ISS)

NASA Image and Video Library

2001-03-13

Astronaut Paul W. Richards, STS-102 mission specialist, works in the cargo bay of the Space Shuttle Discovery during the second of two scheduled space walks. Richards, along with astronaut Andy Thomas, spent 6.5 hours outside the International Space Station (ISS), continuing work to outfit the station and prepare for delivery of its robotic arm. STS-102 delivered the first Multipurpose Logistics Modules (MPLM) named Leonardo, which was filled with equipment and supplies to outfit the U.S. Destiny Laboratory Module. The Leonardo MPLM is the first of three such pressurized modules that will serve as the ISS' moving vans, carrying laboratory racks filled with equipment, experiments, and supplies to and from the Station aboard the Space Shuttle. The cylindrical module is approximately 21-feet long and 15- feet in diameter, weighing almost 4.5 tons. It can carry up to 10 tons of cargo in 16 standard Space Station equipment racks. Of the 16 racks the module can carry, 5 can be furnished with power, data, and fluid to support refrigerators or freezers. In order to function as an attached station module as well as a cargo transport, the logistics module also includes components that provide life support, fire detection and suppression, electrical distribution, and computer functions. NASA's 103rd overall mission and the 8th Space Station Assembly Flight, STS-102 mission also served as a crew rotation flight. It delivered the Expedition Two crew to the Station and returned the Expedition One crew back to Earth.

International Space Station (ISS)

NASA Image and Video Library

2001-03-10

STS-102 mission astronauts James S. Voss and James D. Weatherbee share a congratulatory handshake as the Space Shuttle Orbiter Discovery successfully docks with the International Space Station (ISS). Photographed from left to right are: Astronauts Susan J. Helms, mission specialist; James S. Voss, Expedition 2 crew member; James D. Weatherbee, mission commander; Andrew S.W. Thomas, mission specialist; and nearly out of frame is James M. Kelley, Pilot. Launched March 8, 2001, STS-102's primary cargo was the Leonardo, the Italian Space Agency-built Multipurpose Logistics Module (MPLM). The Leonardo MPLM is the first of three such pressurized modules that will serve as ISS' moving vans, carrying laboratory racks filled with equipment, experiments, and supplies to and from the Station aboard the Space Shuttle. The cylindrical module is approximately 21-feet long and 15- feet in diameter, weighing almost 4.5 tons. It can carry up to 10 tons of cargo in 16 standard Space Station equipment racks. Of the 16 racks the module can carry, 5 can be furnished with power, data, and fluid to support refrigerators or freezers. In order to function as an attached station module as well as a cargo transport, the logistics module also includes components that provide life support, fire detection and suppression, electrical distribution, and computer functions. NASA's 103rd overall mission and the 8th Space Station Assembly Flight, STS-102 mission also served as a crew rotation flight. It delivered the Expedition Two crew to the Station and returned the Expedition One crew back to Earth.

STS-102 Astronaut Paul Richards Participates in Space Walk

NASA Technical Reports Server (NTRS)

2001-01-01

Astronaut Paul W. Richards, STS-102 mission specialist, works in the cargo bay of the Space Shuttle Discovery during the second of two scheduled space walks. Richards, along with astronaut Andy Thomas, spent 6.5 hours outside the International Space Station (ISS), continuing work to outfit the station and prepare for delivery of its robotic arm. STS-102 delivered the first Multipurpose Logistics Modules (MPLM) named Leonardo, which was filled with equipment and supplies to outfit the U.S. Destiny Laboratory Module. The Leonardo MPLM is the first of three such pressurized modules that will serve as the ISS' moving vans, carrying laboratory racks filled with equipment, experiments, and supplies to and from the Station aboard the Space Shuttle. The cylindrical module is approximately 21-feet long and 15- feet in diameter, weighing almost 4.5 tons. It can carry up to 10 tons of cargo in 16 standard Space Station equipment racks. Of the 16 racks the module can carry, 5 can be furnished with power, data, and fluid to support refrigerators or freezers. In order to function as an attached station module as well as a cargo transport, the logistics module also includes components that provide life support, fire detection and suppression, electrical distribution, and computer functions. NASA's 103rd overall mission and the 8th Space Station Assembly Flight, STS-102 mission also served as a crew rotation flight. It delivered the Expedition Two crew to the Station and returned the Expedition One crew back to Earth.

Light Microscopy Module Fan Disturbance Characterized Through Microgravity Emissions Laboratory Testing

NASA Technical Reports Server (NTRS)

McNelis, Anne M.; Motil, Susan M.

2003-01-01

A Light Microscopy Module (LMM) is being engineered, designed, and developed at the NASA Glenn Research Center. The LMM is planned as a remotely controllable on-orbit microscope subrack facility, allowing flexible scheduling and control of physical science and biological science experiments within Glenn s Fluids Integrated Rack on the International Space Station. The LMM concept is a modified commercial research imaging light microscope with powerful laser-diagnostic hardware and interfaces, creating a one-of-a-kind, state-of-the-art microscopic research facility. The microscope will house several different objectives, corresponding to magnifications of 10, 40, 50, 63, and 100. Features of the LMM include high-resolution color video microscopy, brightfield, darkfield, phase contrast, differential interference contrast, spectrophotometry, and confocal microscopy combined in a single configuration. Also, laser tweezers are integrated with the diagnostics as a sample manipulation technique. As part of the development phase of the LMM, it was necessary to quantify the microgravity disturbances generated by the control box fan. Isolating the fan was deemed necessary to reduce the fan speed harmonic amplitudes and to eliminate any broadband disturbances across the 60- to 70-Hz and 160- to 170-Hz frequency ranges. The accelerations generated by a control box fan component of the LMM were measured in the Microgravity Emissions Laboratory (MEL). The MEL is a low-frequency measurement system developed to simulate and verify the on-orbit International Space Station (ISS) microgravity environment. The accelerations generated by various operating components of the ISS, if too large, could hinder the science performed onboard by disturbing the microgravity environment. The MEL facility gives customers a test-verified way of measuring their compliance with ISS limitations on vibratory disturbance levels. The facility is unique in that inertial forces in 6 degrees of freedom can be characterized simultaneously for an operating test article. Vibratory disturbance levels are measured for engineering or flight-level hardware following development from component to subassembly through the rack-level configuration. The MEL can measure accelerations as small as 10-7g, the accuracy needed to confirm compliance with ISS requirements.

Adaptor proteins in protein kinase C-mediated signal transduction.

PubMed

Schechtman, D; Mochly-Rosen, D

2001-10-01

Spatial and temporal organization of signal transduction is essential in determining the speed and precision by which signaling events occur. Adaptor proteins are key to organizing signaling enzymes near their select substrates and away from others in order to optimize precision and speed of response. Here, we describe the role of adaptor proteins in determining the specific function of individual protein kinase C (PKC) isozymes. These isozyme-selective proteins were called collectively RACKs (receptors for activated C-kinase). The role of RACKs in PKC-mediated signaling was determined using isozyme-specific inhibitors and activators of the binding of each isozyme to its respective RACK. In addition to anchoring activated PKC isozymes, RACKs anchor other signaling enzymes. RACK1, the anchoring protein for activated betaIIPKC, binds for example, Src tyrosine kinase, integrin, and phosphodiesterase. RACK2, the epsilonPKC-specific RACK, is a coated-vesicle protein and thus is involved in vesicular release and cell-cell communication. Therefore, RACKs are not only adaptors for PKC, but also serve as adaptor proteins for several other signaling enzymes. Because at least some of the proteins that bind to RACKs, including PKC itself, regulate cell growth, modulating their interactions with RACKs may help elucidate signaling pathways leading to carcinogenesis and could result in the identification of novel therapeutic targets.

Canine melanoma diagnosis: RACK1 as a potential biological marker.

PubMed

Campagne, C; Julé, S; Alleaume, C; Bernex, F; Ezagal, J; Château-Joubert, S; Estrada, M; Aubin-Houzelstein, G; Panthier, J-J; Egidy, G

2013-11-01

Melanoma diagnosis in dogs can be challenging due to the variety of histological appearances of canine melanocytic neoplasms. Markers of malignancy are needed. Receptor for activated C-kinase 1 (RACK1) was found to characterize melanomas in other mammals. We investigated the value of RACK1 detection in the classification of 19 cutaneous and 5 mucosal melanocytic neoplasms in dogs. These tumors were categorized as melanocytomas or benign and melanomas or malignant after evaluation of their morphology, mitotic index, and Ki-67 growth fraction. Using immunofluorescence, we confirmed microphthalmia-associated transcription factor (MITF) as a marker of normal and transformed melanocytic cells in dog tissues. All control (n = 10) and tumoral (n = 24) samples stained positively for MITF (34/34, 100%). Whereas RACK1 was not detected in healthy skin melanocytes, melanocytic lesions were all positive for RACK1 signal (24/24, 100%). RACK1 cytoplasmic staining appeared with 2 distinct distribution patterns: strong, diffuse, and homogeneous or granular and heterogeneous. All melanoma samples (13/13, 100%) stained homogeneously for RACK1. All melanocytomas (11/11, 100%) stained heterogeneously for RACK1. Immunohistochemistry was less consistent than immunofluorescence for all labelings in melanocytic lesions, which were often very pigmented. Thus, the fluorescent RACK1-MITF labeling pattern helped to distinguish melanomas from melanocytomas. Furthermore, RACK1 labeling correlated with 2 of 11 morphological features linked to malignancy: cell and nuclear size. These results suggest that RACK1 may be used as a marker in dog melanomas.

Arabidopsis scaffold protein RACK1A modulates rare sugar D-allose regulated gibberellin signaling.

PubMed

Fennell, Herman; Olawin, Abdulquadri; Mizanur, Rahman M; Izumori, Ken; Chen, Jin-Gui; Ullah, Hemayet

2012-11-01

As energy sources and structural components, sugars are the central regulators of plant growth and development. In addition to the abundant natural sugars in plants, more than 50 different kinds of rare sugars exist in nature, several of which show distinct roles in plant growth and development. Recently, one of the rare sugars, D-allose, an epimer of D-glucose at C3, is found to suppress plant hormone gibberellin (GA) signaling in rice. Scaffold protein RACK1A in the model plant Arabidopsis is implicated in the GA pathway as rack1a knockout mutants show insensitivity to GA in GA-induced seed germination. Using genetic knockout lines and a reporter gene, the functional role of RACK1A in the D-allose pathway was investigated. It was found that the rack1a knockout seeds showed hypersensitivity to D-allose-induced inhibition of seed germination, implicating a role for RACK1A in the D-allose mediated suppression of seed germination. On the other hand, a functional RACK1A in the background of the double knockout mutations in the other two RACK1 isoforms, rack1b/rack1c, showed significant resistance to the D-allose induced inhibition of seed germination. The collective results implicate the RACK1A in the D-allose mediated seed germination inhibition pathway. Elucidation of the rare sugar signaling mechanism will help to advance understanding of this less studied but important cellular signaling pathway.

Arabidopsis scaffold protein RACK1A modulates rare sugar D-allose regulated gibberellin signaling

PubMed Central

Fennell, Herman; Olawin, Abdulquadri; Mizanur, Rahman M.; Izumori, Ken; Chen, Jin-Gui; Ullah, Hemayet

2012-01-01

As energy sources and structural components, sugars are the central regulators of plant growth and development. In addition to the abundant natural sugars in plants, more than 50 different kinds of rare sugars exist in nature, several of which show distinct roles in plant growth and development. Recently, one of the rare sugars, D-allose, an epimer of D-glucose at C3, is found to suppress plant hormone gibberellin (GA) signaling in rice. Scaffold protein RACK1A in the model plant Arabidopsis is implicated in the GA pathway as rack1a knockout mutants show insensitivity to GA in GA-induced seed germination. Using genetic knockout lines and a reporter gene, the functional role of RACK1A in the D-allose pathway was investigated. It was found that the rack1a knockout seeds showed hypersensitivity to D-allose-induced inhibition of seed germination, implicating a role for RACK1A in the D-allose mediated suppression of seed germination. On the other hand, a functional RACK1A in the background of the double knockout mutations in the other two RACK1 isoforms, rack1b/rack1c, showed significant resistance to the D-allose induced inhibition of seed germination. The collective results implicate the RACK1A in the D-allose mediated seed germination inhibition pathway. Elucidation of the rare sugar signaling mechanism will help to advance understanding of this less studied but important cellular signaling pathway. PMID:22951405

p65 fragments, homologous to the C2 region of protein kinase C, bind to the intracellular receptors for protein kinase C.

PubMed

Mochly-Rosen, D; Miller, K G; Scheller, R H; Khaner, H; Lopez, J; Smith, B L

1992-09-08

Receptors for activated protein kinase C (RACKs) have been isolated from the particulate cell fraction of heart and brain. We previously demonstrated that binding of protein kinase C (PKC) to RACKs requires PKC activators and is via a site on PKC that is distinct from the substrate binding site. Here, we examine the possibility that the C2 region in the regulatory domain of PKC is involved in binding of PKC to RACKs. The synaptic vesicle-specific p65 protein contains two regions homologous to the C2 region of PKC. We found that three p65 fragments, containing either one or two of these PKC C2 homologous regions, bound to highly purified RACKs. Binding of the p65 fragments and PKC to RACKs was mutually exclusive; preincubation of RACKs with the p65 fragments inhibited PKC binding, and preincubation of RACKs with PKC inhibited binding of the p65 fragments. Preincubation of the p65 fragments with a peptide resembling the PKC binding site on RACKs also inhibited p65 binding to RACKs, suggesting that PKC and p65 bind to the same or nearby regions on RACKs. Since the only homologous region between PKC and the p65 fragments is the C2 region, these results suggest that the C2 region on PKC contains at least part of the RACK binding site.

Hopkins works with the MDCA hardware replacement, and CIR maintenance

NASA Image and Video Library

2013-12-31

ISS038-E-024145 (30 Dec. 2013) --- NASA astronaut Mike Hopkins, Expedition 38 flight engineer, performs in-flight maintenance on combustion research hardware in the Destiny laboratory of the International Space Station. Hopkins replaced a Multi-user Droplet Combustion Apparatus (MDCA) fuel reservoir inside the Combustion Integrated Rack (CIR).

The CGE-PLATO Electronic Laboratory Station Structure and Operation.

ERIC Educational Resources Information Center

Neal, J. P.

An electronic laboratory station was designed for student use in learning electronic instrumentation and measurement by means of the computer-guided experimentation (CGE) system. The station features rack-mounted electronic laboratory equipment on a laboratory table adjacent to a PLATO IV terminal. An integrated logic system behind the laboratory…

Materials Science Research Rack-1 Fire Suppressant Distribution Test Report

NASA Technical Reports Server (NTRS)

Wieland, P. O.

2002-01-01

Fire suppressant distribution testing was performed on the Materials Science Research Rack-1 (MSRR-1), a furnace facility payload that will be installed in the U.S. Lab module of the International Space Station. Unlike racks that were tested previously, the MSRR-1 uses the Active Rack Isolation System (ARIS) to reduce vibration on experiments, so the effects of ARIS on fire suppressant distribution were unknown. Two tests were performed to map the distribution of CO2 fire suppressant throughout a mockup of the MSRR-1 designed to have the same component volumes and flowpath restrictions as the flight rack. For the first test, the average maximum CO2 concentration for the rack was 60 percent, achieved within 45 s of discharge initiation, meeting the requirement to reach 50 percent throughout the rack within 1 min. For the second test, one of the experiment mockups was removed to provide a worst-case configuration, and the average maximum CO2 concentration for the rack was 58 percent. Comparing the results of this testing with results from previous testing leads to several general conclusions that can be used to evaluate future racks. The MSRR-1 will meet the requirements for fire suppressant distribution. Primary factors that affect the ability to meet the CO2 distribution requirements are the free air volume in the rack and the total area and distribution of openings in the rack shell. The length of the suppressant flowpath and degree of tortuousness has little correlation with CO2 concentration. The total area of holes in the rack shell could be significantly increased. The free air volume could be significantly increased. To ensure the highest maximum CO2 concentration, the PFE nozzle should be inserted to the stop on the nozzle.

OsRACK1 Is Involved in Abscisic Acid- and H2O2-Mediated Signaling to Regulate Seed Germination in Rice (Oryza sativa, L.)

PubMed Central

Zhang, Dongping; Chen, Li; Li, Dahong; Lv, Bing; Chen, Yun; Chen, Jingui; XuejiaoYan; Liang, Jiansheng

2014-01-01

The receptor for activated C kinase 1 (RACK1) is one member of the most important WD repeat–containing family of proteins found in all eukaryotes and is involved in multiple signaling pathways. However, compared with the progress in the area of mammalian RACK1, our understanding of the functions and molecular mechanisms of RACK1 in the regulation of plant growth and development is still in its infancy. In the present study, we investigated the roles of rice RACK1A gene (OsRACK1A) in controlling seed germination and its molecular mechanisms by generating a series of transgenic rice lines, of which OsRACK1A was either over-expressed or under-expressed. Our results showed that OsRACK1A positively regulated seed germination and negatively regulated the responses of seed germination to both exogenous ABA and H2O2. Inhibition of ABA biosynthesis had no enhancing effect on germination, whereas inhibition of ABA catabolism significantly suppressed germination. ABA inhibition on seed germination was almost fully recovered by exogenous H2O2 treatment. Quantitative analyses showed that endogenous ABA levels were significantly higher and H2O2 levels significantly lower in OsRACK1A-down regulated transgenic lines as compared with those in wildtype or OsRACK1A-up regulated lines. Quantitative real-time PCR analyses showed that the transcript levels of OsRbohs and amylase genes, RAmy1A and RAmy3D, were significantly lower in OsRACK1A-down regulated transgenic lines. It is concluded that OsRACK1A positively regulates seed germination by controlling endogenous levels of ABA and H2O2 and their interaction. PMID:24865690

Kale BoRACK1 is involved in the plant response to salt stress and Peronospora brassicae Gaumann.

PubMed

Li, Da-Hong; Shen, Fu-Jia; Li, Hong-Yan; Li, Wei

2017-06-01

The receptor for activated C kinase 1 (RACK1) belongs to a protein subfamily containing a tryptophan-aspartic acid-domain (WD) repeat structure. Compelling evidence indicates that RACK1 can interact with many signal molecules and affect different signal transduction pathways. In this study, a kale (Brassica oleracea var. acephala f.tricolor) RACK1 gene (BoRACK1) was cloned by RT-PCR. The amino acid sequence of BoRACK1 had seven WD repeats in which there were typical GH (glycine-histidine) and WD dipeptides. Comparison with AtRACK1 from Arabidopsis revealed 87.1% identity at the amino acid level. Expression pattern analysis by RT-PCR showed that BoRACK1 was expressed in all analyzed tissues of kale and that its transcription in leaves was down-regulated by salt, abscisic acid, and H 2 O 2 at a high concentration. Overexpression of BoRACK1 in kale led to a reduction in symptoms caused by Peronospora brassicae Gaumann on kale leaves. The expression levels of the pathogenesis-related protein genes, PR-1 and PRB-1, increased 2.5-4-fold in transgenic kale, and reactive oxygen species production was more active than in the wild-type. They also exhibited increased tolerance to salt stress in seed germination. H 2 O 2 may also be involved in the regulation of BoRACK1 during seed germination under salt stress. Quantitative real-time PCR analyses showed that the transcript levels of BoRbohs genes were significantly higher in overexpression of BoRACK1 transgenic lines. Yeast two-hybrid assays showed that BoRACK1 could interact with WNK8, eIF6, RAR1, and SGT1. This study and previous work lead us to believe that BoRACK1 may form a complex with regulators of plant salt and disease resistance to coordinate kale reactions to pathogens. Copyright © 2017 Elsevier GmbH. All rights reserved.

40 CFR 63.982 - Requirements.

Code of Federal Regulations, 2010 CFR

2010-07-01

..., transfer racks, and equipment leaks. An owner or operator who is referred to this subpart for controlling regulated material emissions from storage vessels, process vents, low and high throughput transfer racks, or... racks. (i) For low throughput transfer racks, the owner or operator shall comply with the applicable...

RACK1 promotes radiation resistance in esophageal cancer via regulating AKT pathway and Bcl-2 expression.

PubMed

Liu, Bowen; Wang, Cong; Chen, Pengxiang; Wang, Lu; Cheng, Yufeng

2017-09-23

RACK1 is a seven Trp-Asp 40 repeat protein, which interacts with a wide range of kinases and proteins. RACK1 plays an important role in the proliferation and progression of various cancers. The aim of this study is to detect the role of RACK1 in the radioresistance in esophageal cancer. The results indicated that downregulation of RACK1 reduced the colony formation ability, proliferation ability and resistance of cells to radiation effection through regulating the radiation-related proteins including pAKT, Bcl-2 and Bim; whereas upregulation of RACK1 promoted the ability and radioresistance of ESCC cells. Our findings suggest that RACK1 promotes proliferation and radioresistance in ESCC cells by activating the AKT pathway, upregulating Bcl-2 expression and downregulating protein levels of Bim. Our study fills in gaps in the field of RACK1 and radiation resistance and may provide new possibilities for improving strategies of radiotherapy in esophageal cancer. Copyright © 2017 Elsevier Inc. All rights reserved.

NASA Microgravity Combustion Science Research Plans for the ISS

NASA Technical Reports Server (NTRS)

Sutliff, Thomas J.

2003-01-01

A peer-reviewed research program in Microgravity Combustion Science has been chartered by the Physical Sciences Research Division of the NASA Office of Biological and Physical Research. The scope of these investigations address both fundamental combustion phenomena and applied combustion research topics of interest to NASA. From this pool of research, flight investigations are selected which benefit from access to a microgravity environment. Fundamental research provides insights to develop accurate simulations of complex combustion processes and allows developers to improve the efficiency of combustion devices, to reduce the production of harmful emissions, and to reduce the incidence of accidental uncontrolled combustion (fires, explosions). Through its spacecraft fire safety program, applied research is conducted to decrease risks to humans living and working in space. The Microgravity Combustion Science program implements a structured flight research process utilizing the International Space Station (ISS) and two of its premier facilities- the Combustion Integrated Rack of the Fluids and Combustion Facility and the Microgravity Science Glovebox - to conduct space-based research investigations. This paper reviews the current plans for Microgravity Combustion Science research on the International Space Station from 2003 through 2012.

FEANICS: A Multi-User Facility For Conducting Solid Fuel Combustion Experiments On ISS

NASA Technical Reports Server (NTRS)

Frate, David T.; Tofil, Todd A.

2001-01-01

The Destiny Module on the International Space Station (ISS) will soon be home for the Fluids and Combustion Facility's (FCF) Combustion Integrated Rack (CIR), which is being developed at the NASA Glenn Research Center in Cleveland, Ohio. The CIR will be the platform for future microgravity combustion experiments. A multi-user mini-facility called FEANICS (Flow Enclosure Accommodating Novel Investigations in Combustion of Solids) will also be built at NASA Glenn. This mini-facility will be the primary means for conducting solid fuel combustion experiments in the CIR on ISS. The main focus of many of these solid combustion experiments will be to conduct basic and applied scientific investigations in fire-safety to support NASA's Bioastronautics Initiative. The FEANICS project team will work in conjunction with the CIR project team to develop upgradeable and reusable hardware to meet the science requirements of current and future investigators. Currently, there are six experiments that are candidates to use the FEANICS mini-facility. This paper will describe the capabilities of this mini-facility and the type of solid combustion testing and diagnostics that can be performed.

Fuel consumption impacts of auto roof racks

DOE PAGES

Chen, Yuche; Meier, Alan

2016-03-23

The after-market roof rack is one of the most common components attached to a vehicle for carrying over-sized items, such as bicycles and skis. It is important to understand these racks' fuel consumption impacts on both individual vehicles and the national fleet because they are widely used. We estimate the national fuel consumption impacts of roof racks using a bottom-up approach. Our model incorporates real-world data and vehicle stock information to enable assessing fuel consumption impacts for several categories of vehicles, rack configurations, and usage conditions. In addition, the model draws on two new data-gathering techniques, on-line forums and crowd-sourcing.more » The results show that nationwide, roof racks are responsible for 0.8‰ of light duty vehicle fuel consumption in 2015, corresponding to 100 million gallons of gasoline per year. Sensitivity analyses show that results are most sensitive to the fraction of vehicles with installed roof racks but carrying no equipment. Here, the aerodynamic efficiency of typical roof racks can be greatly improved and reduce individual vehicle fuel consumption; however, government policies to minimize extensive driving with empty racks--if successful--could save more fuel nationally.« less

System and method for object localization

NASA Technical Reports Server (NTRS)

Kelly, Alonzo J. (Inventor); Zhong, Yu (Inventor)

2005-01-01

A computer-assisted method for localizing a rack, including sensing an image of the rack, detecting line segments in the sensed image, recognizing a candidate arrangement of line segments in the sensed image indicative of a predetermined feature of the rack, generating a matrix of correspondence between the candidate arrangement of line segments and an expected position and orientation of the predetermined feature of the rack, and estimating a position and orientation of the rack based on the matrix of correspondence.

The role of HSP27 in RACK1-mediated PKC activation in THP-1 cells.

PubMed

Corsini, Emanuela; Galbiati, Valentina; Papale, Angela; Kummer, Elena; Pinto, Antonella; Guaita, Antonio; Racchi, Marco

2016-08-01

Receptor for Activated C Kinase 1 (RACK1) pseudosubstrate is a commercially available peptide that directly activates protein kinase C-β (PKCβ). We have recently shown that RACK1 pseudosubstrate, alone or in combination with classical immune activators, results in increased cytokine production and CD86 upregulation in primary leukocytes. Furthermore, we demonstrated a role of PKCβ and RACK1 in chemical allergen-induced CD86 expression and IL-8 production in both THP-1 cells and primary human dendritic cells. Aim of this study was to shed light on the mechanisms underlying RACK1 pseudosubstrate-induced immune activation and to compare it to lipopolysaccharide (LPS). The human promyelocytic cell line THP-1 was used throughout the study. RACK1 pseudosubstrate induced rapid (5 min) and dose-related PKCβ activation as assessed by its membrane translocation. Among the proteins phosphorylated, we identified Hsp27. Both RACK1 pseudosubstrate and LPS induce its phosphorylation and release in culture medium. The release of Hsp27 induced by RACK1 pseudosubstrate was also confirmed in peripheral blood mononuclear cells. To evaluate the role of Hsp27 in RACK1 pseudosubstrate or LPS-induced cell activation, we conducted Hsp27 silencing and neutralization experiments. Both strategies confirmed the central role of Hsp27 in RACK1 pseudosubstrate or LPS-induced cell activation, as assessed by IL-8 production and upregulation of CD86.

Patterns of structural dynamics in RACK1 protein retained throughout evolution: A hydrogen-deuterium exchange study of three orthologs

PubMed Central

Tarnowski, Krzysztof; Fituch, Kinga; Szczepanowski, Roman H; Dadlez, Michal; Kaus-Drobek, Magdalena

2014-01-01

RACK1 is a member of the WD repeat family of proteins and is involved in multiple fundamental cellular processes. An intriguing feature of RACK1 is its ability to interact with at least 80 different protein partners. Thus, the structural features enabling such interactomic flexibility are of great interest. Several previous studies of the crystal structures of RACK1 orthologs described its detailed architecture and confirmed predictions that RACK1 adopts a seven-bladed β-propeller fold. However, this did not explain its ability to bind to multiple partners. We performed hydrogen-deuterium (H-D) exchange mass spectrometry on three orthologs of RACK1 (human, yeast, and plant) to obtain insights into the dynamic properties of RACK1 in solution. All three variants retained similar patterns of deuterium uptake, with some pronounced differences that can be attributed to RACK1's divergent biological functions. In all cases, the most rigid structural elements were confined to B-C turns and, to some extent, strands B and C, while the remaining regions retained much flexibility. We also compared the average rate constants for H-D exchange in different regions of RACK1 and found that amide protons in some regions exchanged at least 1000-fold faster than in others. We conclude that its evolutionarily retained structural architecture might have allowed RACK1 to accommodate multiple molecular partners. This was exemplified by our additional analysis of yeast RACK1 dimer, which showed stabilization, as well as destabilization, of several interface regions upon dimer formation. PMID:24591271

The Dictyostelium discoideum RACK1 orthologue has roles in growth and development

PubMed Central

2014-01-01

Background The receptor for activated C-kinase 1 (RACK1) is a conserved protein belonging to the WD40 repeat family of proteins. It folds into a beta propeller with seven blades which allow interactions with many proteins. Thus it can serve as a scaffolding protein and have roles in several cellular processes. Results We identified the product of the Dictyostelium discoideum gpbB gene as the Dictyostelium RACK1 homolog. The protein is mainly cytosolic but can also associate with cellular membranes. DdRACK1 binds to phosphoinositides (PIPs) in protein-lipid overlay and liposome-binding assays. The basis of this activity resides in a basic region located in the extended loop between blades 6 and 7 as revealed by mutational analysis. Similar to RACK1 proteins from other organisms DdRACK1 interacts with G protein subunits alpha, beta and gamma as shown by yeast two-hybrid, pulldown, and immunoprecipitation assays. Unlike the Saccharomyces cerevisiae and Cryptococcus neoformans RACK1 proteins it does not appear to take over Gβ function in D. discoideum as developmental and other defects were not rescued in Gβ null mutants overexpressing GFP-DdRACK1. Overexpression of GFP-tagged DdRACK1 and a mutant version (DdRACK1mut) which carried a charge-reversal mutation in the basic region in wild type cells led to changes during growth and development. Conclusion DdRACK1 interacts with heterotrimeric G proteins and can through these interactions impact on processes specifically regulated by these proteins. PMID:24930026

Deformation and Flexibility Equations for Idealized ARIS Umbilicals, Under Planar End-Loading Conditions

NASA Technical Reports Server (NTRS)

Hampton, R. David; Quraishi, Naveed (Technical Monitor)

2003-01-01

The International Space Station (ISS) relies on the Active Rack Isolation System (ARIS) as the central component of an integrated, station-wide strategy to isolate microgravity space-science experiments. ARIS uses electromechanical actuators to isolate an International Standard Payload Rack (ISPR) from disturbances due to the motion of the ISS. Disturbances to microgravity experiments on ARIS-isolated racks are primarily transmitted via the ARTS power and vacuum umbilicals. Recent experimental tests indicate that these umbilicals resonate at frequencies outside the ARIS controller's bandwidth, at levels of potential concern for certain microgravity experiments. Reduction in the umbilical resonant frequencies could help to address this issue. This report develops equations for the in-plane deflections and flexibilities of an idealized umbilical (thin, flexible, cantilever beam) under end-point, in-plane loading (inclined-force and moment). The effect of gravity is neglected due to the on-orbit application. The analysis assumes an initially straight, cantilevered umbilical with uniform cross-section, which undergoes large deflections with no plastic deformation, such that the umbilical terminus remains in a single quadrant and the umbilical slope changes monotonically. The analysis is applicable to the ARIS power and vacuum umbilicals, under the indicated assumptions.

Deformation and Flexibility Equations for Idealized ARIS Umbilicals, Under Planar End-Loading Conditions

NASA Technical Reports Server (NTRS)

Hampton, R. David; Quraishi, Naveed; Rupert, Jason K.

2000-01-01

The International Space Station (ISS) relies on the Active Rack Isolation System (ARIS) as the central component of an integrated, station-wide strategy to isolate microgravity space-science experiments. ARIS uses electromechanical actuators to isolate an International Standard Payload Rack (ISPR) from disturbances due to the motion of the ISS. Disturbances to microgravity experiments on ARIS-isolated racks are primarily transmitted via the ARIS power and vacuum umbilicals. Recent experimental tests indicate that these umbilicals resonate at frequencies outside the ARIS controller's bandwidth. at levels of potential concern for certain microgravity experiments. Reduction in the umbilical resonant frequencies could help to address this issue. This paper develops equations for the in-plane deflections and flexibilities of an idealized umbilical (thin, flexible, cantilever beam) under end-point, in-plane loading (inclined-force and moment). The effect of gravity is neglected due to the on:orbit application. The analysis assumes an initially straight. cantilevered umbilical with uniform cross-section. which undergoes large deflections with no plastic deformation, such that the umbilical terminus remains in a single quadrant and the umbilical slope changes monotonically. The analysis is applicable to the ARIS power and vacuum umbilicals. under the indicated assumptions.

Deformation and Flexibility Equations for ARIS Umbilicals Idealized as Planar Elastica

NASA Technical Reports Server (NTRS)

Hampton, R. David; Leamy, Michael J.; Bryant, Paul J.; Quraishi, Naveed

2005-01-01

The International Space Station relies on the active rack isolation system (ARIS) as the central component of an integrated, stationwide strategy to isolate microgravity space-science experiments. ARIS uses electromechanical actuators to isolate an international standard payload rack from disturbances due to the motion of the Space Station. Disturbances to microgravity experiments on ARIS isolated racks are transmitted primarily via the ARIS power and vacuum umbilicals. Experimental tests indicate that these umbilicals resonate at frequencies outside the ARIS controller s bandwidth at levels of potential concern for certain microgravity experiments. Reduction in the umbilical resonant frequencies could help to address this issue. This work documents the development and verification of equations for the in-plane deflections and flexibilities of an idealized umbilical (thin, flexible, inextensible, cantilever beam) under end-point, in-plane loading (inclined-force and moment). The effect of gravity is neglected due to the on-orbit application. The analysis assumes an initially curved (not necessarily circular), cantilevered umbilical with uniform cross-section, which undergoes large deflections with no plastic deformation, such that the umbilical slope changes monotonically. The treatment is applicable to the ARIS power and vacuum umbilicals under the indicated assumptions.

21 CFR 882.4215 - Clip rack.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Clip rack. 882.4215 Section 882.4215 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES NEUROLOGICAL DEVICES Neurological Surgical Devices § 882.4215 Clip rack. (a) Identification. A clip rack is a...

40. Upper level, electronic racks, left to rightstatus command message ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

40. Upper level, electronic racks, left to right--status command message processing group, UHF radio, impss rack security, power supply group rack - Ellsworth Air Force Base, Delta Flight, Launch Facility, On County Road T512, south of Exit 116 off I-90, Interior, Jackson County, SD

78 FR 54450 - Certain Kitchen Appliance Shelving and Racks From the People's Republic of China: Preliminary...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-04

... Shelving and Racks From the People's Republic of China: Preliminary Results of Antidumping Duty... the antidumping duty order on certain kitchen appliance shelving and racks from the People's Republic...\\ is certain kitchen appliance shelving and racks. The subject merchandise is currently classifiable...

21 CFR 882.4215 - Clip rack.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Clip rack. 882.4215 Section 882.4215 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES NEUROLOGICAL DEVICES Neurological Surgical Devices § 882.4215 Clip rack. (a) Identification. A clip rack is a...

30 CFR 56.7050 - Tool and drill steel racks.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Tool and drill steel racks. 56.7050 Section 56... Jet Piercing Drilling § 56.7050 Tool and drill steel racks. Receptacles or racks shall be provided for drill steel and tools stored or carried on drills. ...

30 CFR 56.7050 - Tool and drill steel racks.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Tool and drill steel racks. 56.7050 Section 56... Jet Piercing Drilling § 56.7050 Tool and drill steel racks. Receptacles or racks shall be provided for drill steel and tools stored or carried on drills. ...

30 CFR 56.7050 - Tool and drill steel racks.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Tool and drill steel racks. 56.7050 Section 56... Jet Piercing Drilling § 56.7050 Tool and drill steel racks. Receptacles or racks shall be provided for drill steel and tools stored or carried on drills. ...

30 CFR 56.7050 - Tool and drill steel racks.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Tool and drill steel racks. 56.7050 Section 56... Jet Piercing Drilling § 56.7050 Tool and drill steel racks. Receptacles or racks shall be provided for drill steel and tools stored or carried on drills. ...

U.S. Rep. Dave Weldon looks at the U.S. Lab Destiny in the SSPF.

NASA Technical Reports Server (NTRS)

1999-01-01

Inside the U.S. Lab, called 'Destiny,' which is in the Space Station Processing Facility, U.S. Rep. Dave Weldon (right) looks over equipment. In the background (center) is Thomas R. 'Randy' Galloway, with the Space Station Hardware Integration Office. Weldon is on the House Science Committee and vice chairman of the Space and Aeronautics Subcommittee. Destiny is scheduled to be launched on Space Shuttle Endeavour in early 2000. It will become the centerpiece of scientific research on the ISS, with five equipment racks aboard to provide essential functions for station systems, including high data-rate communications, and to maintain the station's orientation using control gyroscopes launched earlier. Additional equipment and research racks will be installed in the laboratory on subsequent Shuttle flights.

U.S. Rep. Dave Weldon outside the U.S. Lab Destiny in the SSPF.

NASA Technical Reports Server (NTRS)

1999-01-01

In the Space Station Processing Facility, U.S. Rep Dave Weldon (at left) looks at the U.S. Lab, called Destiny. With him are Thomas R. 'Randy' Galloway, with the Space Station Hardware Integration Office, Dana Gartzke, the congressman's chief of staffm and Boeing workers. Weldon is on the House Science Committee and vice chairman of the Space and Aeronautics Subcommittee. Destiny is scheduled to be launched on Space Shuttle Endeavour in early 2000. It will become the centerpiece of scientific research on the ISS, with five equipment racks aboard to provide essential functions for station systems, including high data-rate communications, and to maintain the station's orientation using control gyroscopes launched earlier. Additional equipment and research racks will be installed in the laboratory on subsequent Shuttle flights.

ARS racks

NASA Image and Video Library

2009-09-22

ISS020-E-041651 (22 Sept. 2009) --- NASA astronaut Michael Barratt works with the Atmosphere Revitalization System (ARS) rack in the Destiny laboratory of the International Space Station. Barratt, Canadian Space Agency astronaut Robert Thirsk (out of frame) and European Space Agency astronaut Frank De Winne (out of frame), all Expedition 20 flight engineers, spent several hours with the extensive dual-rack swap/install activity, to move Destiny?s ARS rack to the Kibo laboratory and install in Destiny in its place the newly-delivered ARS rack for Node-3.

ARS racks

NASA Image and Video Library

2009-09-22

ISS020-E-041647 (22 Sept. 2009) --- NASA astronaut Michael Barratt works with the Atmosphere Revitalization System (ARS) rack in the Destiny laboratory of the International Space Station. Barratt, Canadian Space Agency astronaut Robert Thirsk (out of frame) and European Space Agency astronaut Frank De Winne (out of frame), all Expedition 20 flight engineers, spent several hours with the extensive dual-rack swap/install activity, to move Destiny?s ARS rack to the Kibo laboratory and install in Destiny in its place the newly-delivered ARS rack for Node-3.

Numerical simulation study on air quality in aircraft cabins.

PubMed

Zhao, Yingjie; Dai, Bingrong; Yu, Qi; Si, Haiqing; Yu, Gang

2017-06-01

Air pollution is one of the main factors that affect the air quality in aircraft cabins, and the use of different air supply modes could influence the distribution of air pollutants in cabins. Based on the traditional ceiling air supply mode used on the B737NG, this study investigated another 3 different kinds of air supply modes for comparison: luggage rack air supply mode, joint mode combining ceiling and luggage rack air supply, and joint mode combining ceiling and individual air supply. Under the above 4 air supply modes, the air velocity, temperature and distribution of air pollutants in a cabin full of passengers were studied using computational fluid dynamics (CFD), and carbon dioxide (CO 2 ) and formaldehyde were selected as 2 kinds of representative air pollutants. The simulation results show that the joint mode combining ceiling and individual air supply can create a more uniform distribution of air velocity and temperature, has a better effect on the removal of CO 2 and formaldehyde, and can provide better air quality in cabins than the other 3 modes. Copyright © 2016. Published by Elsevier B.V.

STS-42 MS/PLC Norman E. Thagard adjusts Rack 10 FES equipment in IML-1 module

NASA Image and Video Library

1992-01-30

STS042-05-006 (22-30 Jan 1992) --- Astronaut Norman E. Thagard, payload commander, performs the Fluids Experiment System (FES) in the International Microgravity Laboratory (IML-1) science module. The FES is a NASA-developed facility that produces optical images of fluid flows during the processing of materials in space. The system's sophisticated optics consist of a laser to make holograms of samples and a video camera to record images of flows in and around samples. Thagard was joined by six fellow crewmembers for eight days of scientific research aboard Discovery in Earth-orbit. Most of their on-duty time was spent in this IML-1 science module, positioned in the cargo bay and attached via a tunnel to Discovery's airlock.

Mini-rack testbed evaluation

NASA Technical Reports Server (NTRS)

Gosbee, John; Stegmann, Barbara; Guess, Terrell M.

1991-01-01

The goal was to characterize the Health Maintenance Facility (HMF)-like mini-racks and drawers onboard the KC-135 as a test bed for the Space Station Freedom HMF racks. An additional goal was to evaluate the attachments, mounting points, and inner drawer assemblies of the mini-racks for various medical equipment and supplies. Results and recommendations are given.

76 FR 27990 - Certain Kitchen Shelving and Racks From the People's Republic of China: Extension of Time Limit...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-13

... Racks From the People's Republic of China: Extension of Time Limit for Preliminary Results of... countervailing duty order on certain kitchen appliance shelving and racks from the People's Republic of China... the Countervailing Duty Administrative Review of Certain Kitchen Appliance Shelving and Racks from the...

78 FR 78815 - Certain Kitchen Appliance Shelving and Racks from the People's Republic of China: Rescission of...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-27

... Shelving and Racks from the People's Republic of China: Rescission of Antidumping Duty Administrative... administrative review of the antidumping duty order on certain kitchen appliance shelving and racks from the... on certain kitchen appliance shelving and racks from the PRC.\\1\\ On September 30, 2013, the...

40 CFR 63.2475 - What requirements must I meet for transfer racks?

Code of Federal Regulations, 2010 CFR

2010-07-01

... transfer racks? 63.2475 Section 63.2475 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... must I meet for transfer racks? (a) You must comply with each emission limit and work practice standard in table 5 to this subpart that applies to your transfer racks, and you must meet each applicable...

30 CFR 56.7050 - Tool and drill steel racks.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Tool and drill steel racks. 56.7050 Section 56.7050 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL... Jet Piercing Drilling § 56.7050 Tool and drill steel racks. Receptacles or racks shall be provided for...

77 FR 72324 - Certain Kitchen Appliance Shelving and Racks from the People's Republic of China: Countervailing...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-05

... Shelving and Racks from the People's Republic of China: Countervailing Duty Administrative Review, 2010... countervailing duty order on certain kitchen appliance shelving and racks from the People's Republic of China. See Certain Kitchen Appliance Shelving and Racks From the People's Republic of China: Countervailing...

78 FR 21594 - Certain Kitchen Appliance Shelving and Racks From the People's Republic of China: Final Results...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-11

... Shelving and Racks From the People's Republic of China: Final Results of Countervailing Duty Administrative... countervailing duty (``CVD'') order on certain kitchen appliance shelving and racks from the People's Republic of...\\ See Certain Kitchen Appliance Shelving and Racks From the People's Republic of China: Countervailing...

30 CFR 57.7050 - Tool and drill steel racks.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Tool and drill steel racks. 57.7050 Section 57... Rotary Jet Piercing Drilling-Surface and Underground § 57.7050 Tool and drill steel racks. Receptacles or racks shall be provided for drill steel and tools stored or carried on drills. ...

30 CFR 57.7050 - Tool and drill steel racks.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Tool and drill steel racks. 57.7050 Section 57... Rotary Jet Piercing Drilling-Surface and Underground § 57.7050 Tool and drill steel racks. Receptacles or racks shall be provided for drill steel and tools stored or carried on drills. ...

30 CFR 57.7050 - Tool and drill steel racks.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Tool and drill steel racks. 57.7050 Section 57... Rotary Jet Piercing Drilling-Surface and Underground § 57.7050 Tool and drill steel racks. Receptacles or racks shall be provided for drill steel and tools stored or carried on drills. ...

30 CFR 57.7050 - Tool and drill steel racks.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Tool and drill steel racks. 57.7050 Section 57... Rotary Jet Piercing Drilling-Surface and Underground § 57.7050 Tool and drill steel racks. Receptacles or racks shall be provided for drill steel and tools stored or carried on drills. ...

30 CFR 57.7050 - Tool and drill steel racks.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Tool and drill steel racks. 57.7050 Section 57... Rotary Jet Piercing Drilling-Surface and Underground § 57.7050 Tool and drill steel racks. Receptacles or racks shall be provided for drill steel and tools stored or carried on drills. ...

Decreased Blastocyst Production in Mice Exposed to Increased Rack Noise

PubMed Central

Zamora, Bernadette M; Jiang, Meisheng; Wang, Ying; Chai, Minghua; Lawson, P Timothy; Lawson, Gregory W

2009-01-01

This study was conducted to investigate the possible effect of rack type on the blastocyst yield of mouse embryo donors. The first phase of the study consisted of housing some mice (group A) in a ventilated rack and others (group B) in a static rack in the same room for 3 d, followed by euthanasia for blastocyst collection and corticosterone assay. Parametric tests were used to compare groups. The number of blastocysts per donor was lower in group A (5.0 ± 1.4 blastocysts) than group B (13.1 ± 3.7 blastocysts). Mean noise was higher in the ventilated rack (80.4 dBC) than in the static rack (69.2 dBC). Serum corticosterone concentrations did not differ between groups. For the second phase of the study, a third group of mice (group C) was housed in a static rack without a ventilated rack in the same room. The noise level for group C was even lower (45.18 ± 2.91 dBC), and the blastocyst count per donor (16.4 ± 2.4) was higher than that of group B. The mean noise levels of empty ventilated and static racks differed significantly between groups for 10 different sound frequencies. Plotting mean blastocyst production against mean rack noise revealed a negative linear relationship with good strength of correlation. These results support the earlier observation that decreased blastocyst count occurs following housing of bred C57BL/6 donor mice in ventilated cages. PMID:19807968

RACK1 binds to Smad3 to modulate transforming growth factor-beta1-stimulated alpha2(I) collagen transcription in renal tubular epithelial cells.

PubMed

Okano, Kazuhiro; Schnaper, H William; Bomsztyk, Karol; Hayashida, Tomoko

2006-09-08

Although it is clear that transforming growth factor-beta1 (TGF-beta1) is critical for renal fibrogenesis, the complexity of the involved mechanisms is increasingly apparent. TGF-beta1 stimulates phosphorylation of Smad2/3 and activates other signaling molecules as well. The molecular link between these other kinases and Smads is not known. We sought new binding partners for Smad3 in renal cells and identified receptor for activated protein kinase C 1 (RACK1) as a novel binding partner of Smad3. The linker region of Smad3 and the tryptophan-aspartic acid repeat 6 and 7 of RACK1 are sufficient for the association. RACK1 also interacts with Smad3 in the human kidney epithelial cell line, HKC. Silencing RACK1 increases transcriptional activity of TGF-beta1-responsive promoter sequences of the Smad binding element (SBE), p3TP-Lux, and alpha2(I) collagen. Conversely, overexpressed RACK1 negatively modulates alpha2(I) collagen transcriptional activity in TGF-beta1-stimulated cells. RACK1 did not affect phosphorylation of Smad3 at the C terminus or in the linker region. However, RACK1 reduced direct binding of Smad3 to the SBE motif. Mutating a RACK1 tyrosine at residue 246, but not at 228, decreased the inhibitory effect of RACK1 on both alpha2(I) collagen promoter activity and Smad binding to SBE induced by TGF-beta1. These results suggest that RACK1 modulates transcription of alpha2(I) collagen by TGF-beta1 through interference with Smad3 binding to the gene promoter.

Solid Inflammability Boundary At Low-Speed (SIBAL)

NASA Technical Reports Server (NTRS)

T'ien, J.; Sacksteder, K.; Ferkul, P.; Pettegrew, R.; Street, K.; Kumar, A.; Tolejko, K.; Kleinhenz, J.; Piltch, N.

2003-01-01

This research program is concerned with the effect of low-speed flow on the spreading and extinction processes over solid fuels. The project has passed the Science Concept Review and the experiment is currently scheduled to be performed in the ISS Combustion Integrated Rack. We present an overview of recent and ongoing experimental and theoretical efforts.

CIR fuel reservoir swap closeout

NASA Image and Video Library

2014-08-11

ISS040-E-090493 (11 Aug. 2014) --- NASA astronaut Reid Wiseman, Expedition 40 flight engineer, performs routine in-flight maintenance on the Multi-user Drop Combustion Apparatus (MDCA) inside the Combustion Integrated Rack (CIR) in the Destiny laboratory of the International Space Station. The MDCA contains hardware and software to conduct unique droplet combustion experiments in space.

CIR fuel reservoir swap closeout

NASA Image and Video Library

2014-08-11

ISS040-E-090497 (11 Aug. 2014) --- NASA astronaut Reid Wiseman, Expedition 40 flight engineer, performs routine in-flight maintenance on the Multi-user Drop Combustion Apparatus (MDCA) inside the Combustion Integrated Rack (CIR) in the Destiny laboratory of the International Space Station. The MDCA contains hardware and software to conduct unique droplet combustion experiments in space.

CIR fuel reservoir swap closeout

NASA Image and Video Library

2014-08-11

ISS040-E-090482 (11 Aug. 2014) --- NASA astronaut Reid Wiseman, Expedition 40 flight engineer, performs routine in-flight maintenance on the Multi-user Drop Combustion Apparatus (MDCA) inside the Combustion Integrated Rack (CIR) in the Destiny laboratory of the International Space Station. The MDCA contains hardware and software to conduct unique droplet combustion experiments in space.

CIR fuel reservoir swap closeout

NASA Image and Video Library

2014-08-11

ISS040-E-090484 (11 Aug. 2014) --- NASA astronaut Reid Wiseman, Expedition 40 flight engineer, performs routine in-flight maintenance on the Multi-user Drop Combustion Apparatus (MDCA) inside the Combustion Integrated Rack (CIR) in the Destiny laboratory of the International Space Station. The MDCA contains hardware and software to conduct unique droplet combustion experiments in space.

78 FR 57215 - Waiver of Requirement To Enter Into a Reciprocal Waiver of Claims Agreement With All Customers...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-17

... NanoRacks, LLC, and NanoRacks locker insert and student experiments created under NASA's Student..., and mathematics education initiative.\\2\\ According to its Space Act Agreement with NASA,\\3\\ NanoRacks... opportunities to NanoRacks for the launch of its insert and the experiments the insert carries. Orbital provided...

77 FR 12811 - Certain Kitchen Appliance Shelving and Racks From the People's Republic of China: Partial...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-02

... Shelving and Racks From the People's Republic of China: Partial Rescission of Antidumping Duty... review of the antidumping duty order on certain kitchen appliance shelving and racks from the People's... Appliance Shelving and Racks from the People's Republic of China, dated January 10, 2012; and Letter to the...

76 FR 20950 - Certain Kitchen Appliance Shelving and Racks From the People's Republic of China: Extension of...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-14

... Shelving and Racks From the People's Republic of China: Extension of Time Limits for the Preliminary... appliance shelving and racks from the People's Republic of China (``PRC'') for the period March 5, 2009... Racks from the People's Republic of China,'' dated January 20, 2011. The Department sent its antidumping...

26 CFR 48.4081-3 - Taxable fuel; taxable events other than removal at the terminal rack.

Code of Federal Regulations, 2010 CFR

2010-04-01

... at the terminal rack. 48.4081-3 Section 48.4081-3 Internal Revenue INTERNAL REVENUE SERVICE...; taxable events other than removal at the terminal rack. (a) Overview. Although tax is imposed when taxable fuel is removed from the terminal at the rack, tax also is imposed in certain other situations...

77 FR 22559 - Certain Kitchen Appliance Shelving and Racks From the People's Republic of China: Extension of...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-16

... Shelving and Racks From the People's Republic of China: Extension of Time Limit for the Preliminary Results... administrative review of the antidumping duty order on certain kitchen appliance shelving and racks from the... Appliance Shelving and Racks from the People's Republic of China: Selection of an Additional Mandatory...

78 FR 5414 - Certain Kitchen Appliance Shelving and Racks From the People's Republic of China; 2010-2011...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-25

... Shelving and Racks From the People's Republic of China; 2010-2011; Final Results of Antidumping Duty... of the antidumping duty order on certain kitchen appliance shelving and racks from the People's... September 1, 2010, through August 31, 2011. \\1\\ See Certain Kitchen Appliance Shelving and Racks From the...

77 FR 61385 - Certain Kitchen Appliance Shelving and Racks From the People's Republic of China: Antidumping...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-09

... Shelving and Racks From the People's Republic of China: Antidumping Duty Administrative Review, 2010-2011... administrative review of the antidumping duty order on certain kitchen appliance shelving and racks from the... INFORMATION: Scope of the Order The scope of this order consists of shelving and racks for refrigerators...

77 FR 82 - Certain Kitchen Appliance Shelving and Racks From the People's Republic of China: Extension of...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-03

... Shelving and Racks From the People's Republic of China: Extension of Time Limit for the Final Results of... administrative review of the countervailing duty order on certain kitchen appliance shelving and racks from the... Kitchen Appliance Shelving and Racks From the People's Republic of China: Preliminary Results of the...

Influence of Rack Design and Disease Prevalence on Detection of Rodent Pathogens in Exhaust Debris Samples from Individually Ventilated Caging Systems.

PubMed

Bauer, Beth A; Besch-Williford, Cynthia; Livingston, Robert S; Crim, Marcus J; Riley, Lela K; Myles, Matthew H

2016-11-01

Sampling of bedding debris within the exhaust systems of ventilated racks may be a mechanism for detecting murine pathogens in colony animals. This study examined the effectiveness of detecting pathogens by PCR analysis of exhaust debris samples collected from ventilated racks of 2 different rack designs, one with unfiltered air flow from within the cage to the air-exhaust pathway, and the other had a filter between the cage and the air-exhaust pathway. For 12 wk, racks were populated with either 1 or 5 cages of mice (3 mice per cage) infected with one of the following pathogens: mouse norovirus (MNV), mouse parvovirus (MPV), mouse hepatitis virus (MHV), Helicobacter spp., Pasteurella pneumotropica, pinworms, Entamoeba muris, Tritrichomonas muris, and fur mites. Pathogen shedding by infected mice was monitored throughout the study. In the filter-containing rack, PCR testing of exhaust plenums yielded negative results for all pathogens at all time points of the study. In the rack with open air flow, pathogens detected by PCR analysis of exhaust debris included MHV, Helicobacter spp., P. pneumotropica, pinworms, enteric protozoa, and fur mites; these pathogens were detected in racks housing either 1 or 5 cages of infected mice. Neither MPV nor MNV was detected in exhaust debris, even though prolonged viral shedding was confirmed. These results demonstrate that testing rack exhaust debris from racks with unfiltered air flow detected MHV, enteric bacteria and parasites, and fur mites. However, this method failed to reliably detect MNV or MPV infection of colony animals.

Influence of Rack Design and Disease Prevalence on Detection of Rodent Pathogens in Exhaust Debris Samples from Individually Ventilated Caging Systems

PubMed Central

Bauer, Beth A; Besch-Williford, Cynthia; Livingston, Robert S; Crim, Marcus J; Riley, Lela K; Myles, Matthew H

2016-01-01

Sampling of bedding debris within the exhaust systems of ventilated racks may be a mechanism for detecting murine pathogens in colony animals. This study examined the effectiveness of detecting pathogens by PCR analysis of exhaust debris samples collected from ventilated racks of 2 different rack designs, one with unfiltered air flow from within the cage to the air-exhaust pathway, and the other had a filter between the cage and the air-exhaust pathway. For 12 wk, racks were populated with either 1 or 5 cages of mice (3 mice per cage) infected with one of the following pathogens: mouse norovirus (MNV), mouse parvovirus (MPV), mouse hepatitis virus (MHV), Helicobacter spp., Pasteurella pneumotropica, pinworms, Entamoeba muris, Tritrichomonas muris, and fur mites. Pathogen shedding by infected mice was monitored throughout the study. In the filter-containing rack, PCR testing of exhaust plenums yielded negative results for all pathogens at all time points of the study. In the rack with open air flow, pathogens detected by PCR analysis of exhaust debris included MHV, Helicobacter spp., P. pneumotropica, pinworms, enteric protozoa, and fur mites; these pathogens were detected in racks housing either 1 or 5 cages of infected mice. Neither MPV nor MNV was detected in exhaust debris, even though prolonged viral shedding was confirmed. These results demonstrate that testing rack exhaust debris from racks with unfiltered air flow detected MHV, enteric bacteria and parasites, and fur mites. However, this method failed to reliably detect MNV or MPV infection of colony animals. PMID:27931317

40 CFR 63.2386 - What reports must I submit and when and what information is to be submitted in each?

Code of Federal Regulations, 2010 CFR

2010-07-01

... organic liquids were loaded at transfer racks that are subject to control based on the criteria specified... all transfer racks (except those racks at which only unloading of organic liquids occurs) and of tanks...) For each storage tank and transfer rack subject to control requirements, include periods of planned...

White House Communications Agency (WHCA) Presidential Voice Communications Rack Mount System Mechanical Drawing Package

DTIC Science & Technology

2015-12-01

Rack Mount System Mechanical Drawing Package by Steven P Callaway Approved for public release; distribution unlimited...Laboratory White House Communications Agency (WHCA) Presidential Voice Communications Rack Mount System Mechanical Drawing Package by Steven P...Note 3. DATES COVERED (From - To) 04/2013 4. TITLE AND SUBTITLE White House Communications Agency (WHCA) Presidential Voice Communications Rack

Characterization of receptor of activated C kinase 1 (RACK1) and functional analysis during larval metamorphosis of the oyster Crassostrea angulata.

PubMed

Yang, Bingye; Pu, Fei; Qin, Ji; You, Weiwei; Ke, Caihuan

2014-03-10

During a large-scale screen of the larval transcriptome library of the Portuguese oyster, Crassostrea angulata, the oyster gene RACK, which encodes a receptor of activated protein kinase C protein was isolated and characterized. The cDNA is 1,148 bp long and has a predicted open reading frame encoding 317 aa. The predicted protein shows high sequence identity to many RACK proteins of different organisms including molluscs, fish, amphibians and mammals, suggesting that it is conserved during evolution. The structural analysis of the Ca-RACK1 genomic sequence implies that the Ca-RACK1 gene has seven exons and six introns, extending approximately 6.5 kb in length. It is expressed ubiquitously in many oyster tissues as detected by RT-PCR analysis. The Ca-RACK1 mRNA expression pattern was markedly increased at larval metamorphosis; and was further increased along with Ca-RACK1 protein synthesis during epinephrine-induced metamorphosis. These results indicate that the Ca-RACK1 plays an important role in tissue differentiation and/or in cell growth during larval metamorphosis in the oyster, C. angulata. Copyright © 2013 Elsevier B.V. All rights reserved.

RACK1 is required for adipogenesis.

PubMed

Kong, Qinghua; Gao, Lan; Niu, Yanfen; Gongpan, Pianchou; Xu, Yuhui; Li, Yan; Xiong, Wenyong

2016-11-01

Adipose tissue plays a critical role in metabolic diseases and the maintenance of energy homeostasis. RACK1 has been identified as an adaptor protein involved in multiple intracellular signal transduction pathways and diseases. However, whether it regulates adipogenesis remains unknown. Here, we reported that RACK1 is expressed in 3T3-L1 cells and murine white adipose tissue and that RACK1 knockdown by shRNA profoundly suppressed adipogenesis by reducing the expression of PPAR-γ and C/EBP-β. Depletion of RACK1 increased β-catenin protein levels and activated Wnt signaling. Furthermore, RACK1 knockdown also suppressed the PI3K-Akt-mTOR-S6K signaling pathway by reducing the PI3K p85α, pAkt T473, and S6K p70. Taken together, these results demonstrate that RACK1 is a novel factor required for adipocyte differentiation by emerging Wnt/β-catenin signaling and PI3K-Akt-mTOR-S6K signaling pathway(s). Copyright © 2016 the American Physiological Society.

U.S. Rep. Dave Weldon looks at the U.S. Lab Destiny in the SSPF.

NASA Technical Reports Server (NTRS)

1999-01-01

In the Space Station Processing Facility, Thomas R. 'Randy' Galloway, with the Space Station Hardware Integration Office, points out a feature to U.S. Rep. Dave Weldon (right) in the U.S. Lab, called 'Destiny.' In the far background is Dana Gartzke, the congressman's chief of staff. Weldon is on the House Science Committee and vice chairman of the Space and Aeronautics Subcommittee. Destiny is scheduled to be launched on Space Shuttle Endeavour in early 2000. It will become the centerpiece of scientific research on the ISS, with five equipment racks aboard to provide essential functions for station systems, including high data-rate communications, and to maintain the station's orientation using control gyroscopes launched earlier. Additional equipment and research racks will be installed in the laboratory on subsequent Shuttle flights.

O-GlcNAcylation of RACK1 promotes hepatocellular carcinogenesis.

PubMed

Duan, Fangfang; Wu, Hao; Jia, Dongwei; Wu, Weicheng; Ren, Shifang; Wang, Lan; Song, Shushu; Guo, Xinying; Liu, Fenglin; Ruan, Yuanyuan; Gu, Jianxin

2018-06-01

Aberrant oncogenic mRNA translation and protein O-linked β-N-acetylglucosaminylation (O-GlcNAcylation) are general features during tumorigenesis. Nevertheless, whether and how these two pathways are interlinked remain unknown. Our previous study indicated that ribosomal receptor for activated C-kinase 1 (RACK1) promoted chemoresistance and growth in hepatocellular carcinoma (HCC). The aim of this study is to examine the role of RACK1 O-GlcNAcylation in oncogene translation and HCC carcinogenesis. The site(s) of RACK1 for O-GlcNAcylation was mapped by mass spectrometry analysis. HCC cell lines were employed to examine the effects of RACK1 O-GlcNAcylation on the translation of oncogenic factors and behaviors of tumor cells in vitro. Transgenic knock-in mice were used to detect the role of RACK1 O-GlcNAcylation in modulating HCC tumorigenesis in vivo. The correlation of RACK1 O-GlcNAcylation with tumor progression and relapse were analyzed in clinical HCC samples. We found that ribosomal RACK1 was highly modified by O-GlcNAc at Ser122. O-GlcNAcylation of RACK1 enhanced its protein stability, ribosome binding and interaction with PKCβII (PRKCB), leading to increased eukaryotic translation initiation factor 4E phosphorylation and translation of potent oncogenes in HCC cells. Genetic ablation of RACK1 O-GlcNAcylation at Ser122 dramatically suppressed tumorigenesis, angiogenesis, and metastasis in vitro and in diethylnitrosamine (DEN)-induced HCC mouse model. Increased RACK1 O-GlcNAcylation was also observed in HCC patient samples and correlated with tumor development and recurrence after chemotherapy. These findings demonstrate that RACK1 acts as key mediator linking O-GlcNAc metabolism to cap-dependent translation during HCC tumorigenesis. Targeting RACK1 O-GlcNAcylation provides promising options for HCC treatment. O-GlcNAcylation of ribosomal receptor for activated C-kinase 1 at the amino acid serine122 promotes its stability, ribosome localization and interaction with the protein kinase, PKCβII, thus driving the translation of oncogenes and tumorigenesis of hepatocellular carcinoma. Increased O-GlcNAcylation of ribosomal receptor for activated C-kinase 1 is positively correlated with tumor growth, metastasis and recurrence in patients with hepatocellular carcinoma. Copyright © 2018 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.

Physics of Colloids in Space: Flight Hardware Operations on ISS

NASA Technical Reports Server (NTRS)

Doherty, Michael P.; Bailey, Arthur E.; Jankovsky, Amy L.; Lorik, Tibor

2002-01-01

The Physics of Colloids in Space (PCS) experiment was launched on Space Shuttle STS-100 in April 2001 and integrated into EXpedite the PRocess of Experiments to Space Station Rack 2 on the International Space Station (ISS). This microgravity fluid physics investigation is being conducted in the ISS U.S. Lab 'Destiny' Module over a period of approximately thirteen months during the ISS assembly period from flight 6A through flight 9A. PCS is gathering data on the basic physical properties of simple colloidal suspensions by studying the structures that form. A colloid is a micron or submicron particle, be it solid, liquid, or gas. A colloidal suspension consists of these fine particles suspended in another medium. Common colloidal suspensions include paints, milk, salad dressings, cosmetics, and aerosols. Though these products are routinely produced and used, we still have much to learn about their behavior as well as the underlying properties of colloids in general. The long-term goal of the PCS investigation is to learn how to steer the growth of colloidal structures to create new materials. This experiment is the first part of a two-stage investigation conceived by Professor David Weitz of Harvard University (the Principal Investigator) along with Professor Peter Pusey of the University of Edinburgh (the Co-Investigator). This paper describes the flight hardware, experiment operations, and initial science findings of the first fluid physics payload to be conducted on ISS: The Physics of Colloids in Space.

26 CFR 48.4081-2 - Taxable fuel; tax on removal at a terminal rack.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 26 Internal Revenue 16 2010-04-01 2010-04-01 true Taxable fuel; tax on removal at a terminal rack..., Tread Rubber, and Taxable Fuel Taxable Fuel § 48.4081-2 Taxable fuel; tax on removal at a terminal rack... rack are subject to tax and the position holder with respect to the fuel is liable for the tax. (b...

Hopkins works with the MDCA inside the CIR in the U.S. Laboratory

NASA Image and Video Library

2013-11-12

ISS038-E-001298 (12 Nov. 2013) --- NASA astronaut Michael Hopkins, Expedition 38 flight engineer, works with the Multi-user Drop Combustion Apparatus (MDCA) inside the Combustion Integrated Rack (CIR) in the Destiny laboratory of the International Space Station. The MDCA contains hardware and software to conduct unique droplet combustion experiments in space.

MDCA Needle 1 Replacement

NASA Image and Video Library

2013-04-22

ISS035-E-025557(22 April 2013) ---Multi-user Droplet Combustion Apparatus (MDCA) Hardware Replacement: Cassidy accessed the Combustion Integration Rack (CIR) Combustion Chamber and removed the MDCA Chamber Insert Assembly (CIA). He then replaced the MDCA Needle 1 due to a fuel line that was damaged during previous activities when the MDCA CIA was being removed from the Combustion Chamber.

Crewmember working on the spacelab Zeolite Crystal Growth experiment.

NASA Technical Reports Server (NTRS)

1992-01-01

View showing Payload Specialists Bonnie Dunbar and Larry DeLucas in the aft section of the U. S. Microgravity Laboratory-1. Dunbar is preparing to load a sample in the Crystal Growth Furnace (CGF) Integrated Furnace Experiment Assembly (IFEA) in rack 9 of the Microgravity Laboratory. DeLucas is checking out the multi-purpose Glovebox Facility.

iss053e098185

NASA Image and Video Library

2017-10-12

iss053e098185 (Oct. 12, 2017) --- Flight Engineer Paolo Nespoli works inside the Harmony module to configure the Combustion Integrated Rack and enable the Advanced Combustion Microgravity Experiment (ACME). The primary and secondary goals of ACME are the improved fuel efficiency and reduced pollutant production in practical combustion on Earth, and spacecraft fire prevention through innovative research focused on materials flammability.

MSRR Rack Materials Science Research Rack

NASA Technical Reports Server (NTRS)

Reagan, Shawn

2017-01-01

The Materials Science Research Rack (MSRR) is a research facility developed under a cooperative research agreement between NASA and the European Space Agency (ESA) for materials science investigations on the International Space Station (ISS). The MSRR is managed at the Marshall Space Flight Center (MSFC) in Huntsville, AL. The MSRR facility subsystems were manufactured by Teledyne Brown Engineering (TBE) and integrated with the ESA/EADS-Astrium developed Materials Science Laboratory (MSL) at the MSFC Space Station Integration and Test Facility (SSITF) as part of the Systems Development Operations Support (SDOS) contract. MSRR was launched on STS-128 in August 2009, and is currently installed in the U. S. Destiny Laboratory Module on the ISS. Materials science is an integral part of developing new, safer, stronger, more durable materials for use throughout everyday life. The goal of studying materials processing in space is to develop a better understanding of the chemical and physical mechanisms involved, and how they differ in the microgravity environment of space. To that end, the MSRR accommodates advanced investigations in the microgravity environment of the ISS for basic materials science research in areas such as solidification of metals and alloys. MSRR allows for the study of a variety of materials including metals, ceramics, semiconductor crystals, and glasses. Materials science research benefits from the microgravity environment of space, where the researcher can better isolate chemical and thermal properties of materials from the effects of gravity. With this knowledge, reliable predictions can be made about the conditions required on Earth to achieve improved materials. MSRR is a highly automated facility with a modular design capable of supporting multiple types of investigations. Currently the NASA-provided Rack Support Subsystem provides services (power, thermal control, vacuum access, and command and data handling) to the ESA developed Materials Science Laboratory (MSL) which accommodates interchangeable Furnace Inserts (FI). Two ESA-developed FIs are presently available on the ISS: the Low Gradient Furnace (LGF) and the Solidification and Quenching Furnace (SQF). Sample-Cartridge Assemblies (SCAs), each containing one or more material samples, are installed in the FI by the crew and can be processed at temperatures up to 1400 C. Once an SCA is installed, the experiment can be run by automatic command or science conducted via telemetry commands from the ground. This facility is available to support materials science investigations through programs such as the US National Laboratory, Technology Development, NASA Research Announcements, and others. TBE and MSFC are currently developing NASA Sample Cartridge Assemblies (SCA's) with a planned availability for launch in 2017.

RACK-1 regulates let-7 microRNA expression and terminal cell differentiation in Caenorhabditis elegans

PubMed Central

Chu, Yu-De; Wang, Wei-Chieh; Chen, Shi-An A; Hsu, Yen-Ting; Yeh, Meng-Wei; Slack, Frank J; Chan, Shih-Peng

2014-01-01

The let-7 microRNA (miRNA) regulates cell cycle exit and terminal differentiation in the C. elegans heterochronic gene pathway. Low expression of let-7 results in retarded vulva and hypodermal cell development in C. elegans and has been associated with several human cancers. Previously, the versatile scaffold protein receptor for activated C kinase 1 (RACK1) was proposed to facilitate recruitment of the miRNA-induced silencing complex (miRISC) to the polysome and to be required for miRNA function in C. elegans and humans. Here, we show that depletion of C. elegans RACK-1 by RNAi increases let-7 miRNA levels and suppresses the retarded terminal differentiation of lateral hypodermal seam cells in mutants carrying the hypomorphic let-7(n2853) allele or lacking the let-7 family miRNA genes mir-48 and mir-241. Depletion of RACK-1 also increases the levels of precursor let-7 miRNA. When Dicer is knocked down and pre-miRNA processing is inhibited, depletion of RACK-1 still leads to increased levels of pre-let-7, suggesting that RACK-1 affects a biogenesis mechanism upstream of Dicer. No changes in the activity of the let-7 promoter or the levels of primary let-7 miRNA are associated with depletion of RACK-1, suggesting that RACK-1 affects let-7 miRNA biogenesis at the post-transcriptional level. Interestingly, rack-1 knockdown also increases the levels of a few other precursor miRNAs. Our results reveal that RACK-1 controls the biogenesis of a subset of miRNAs, including let-7, and in this way plays a role in the heterochronic gene pathway during C. elegans development. PMID:24776851

Server rack for improved data center management

DOEpatents

Bermudez Rodriguez, Sergio A.; Hamann, Hendrik F.; Wehle, Hans-Dieter

2018-01-09

Methods and systems for data center management include collecting sensor data from one or more sensors in a rack; determining a location and identifying information for each asset in the rack using a set of asset tags associated with respective assets; communicating the sensor and asset location to a communication module; receiving an instruction from the communication module; and executing the received instruction to change a property of the rack.

Racking strength of walls sheathed with structual flakeboards made from southern species

Treesearch

E.W. Price; Gromala D.S.

1980-01-01

Ten types of structural flakeboards and two types of southern pine plywood were evaluated. Racking loads were applied to full-size racking panels (8 by 8 ft., according to ASTME 72) and small panels (2 by 2 ft.). When subjected to a 1,600-pound racking load, 8- by 8-foot panels sheathed with flakeboards containing a mixture of hardwood and pine flakes were slightly...

RACK1, a clue to the diagnosis of cutaneous melanomas in horses.

PubMed

Campagne, Cécile; Julé, Sophia; Bernex, Florence; Estrada, Mercedes; Aubin-Houzelstein, Geneviève; Panthier, Jean-Jacques; Egidy, Giorgia

2012-06-29

Melanocytic proliferations are common in horses but the diagnosis of malignancy is not always straightforward. To improve diagnosis and prognosis, markers of malignancy are needed. Receptor for activated C kinase 1 (RACK1) protein may be such a marker. RACK1 was originally found to characterize malignant melanocytic lesions in the Melanoblastoma-bearing Libechov minipig (MeLiM) and, later, in human patients. Our purpose was to investigate the value of RACK1 in the classification of cutaneous melanocytic proliferations in horses. Using immunofluorescence, we report here that both MITF (Microphthalmia-associated transcription factor) and PAX3 (Paired box 3) allow the identification of melanocytic cells in horse skin samples. Importantly, RACK1 was detected in melanocytic lesions but not in healthy skin melanocytes. Finally, we found that RACK1 labeling can be used in horses to distinguish benign melanocytic tumors from melanomas. Indeed, RACK1 labeling appeared more informative to assess malignancy than individual histomorphological features. This study confirms that horses provide an interesting model for melanoma genesis studies. It establishes MITF and PAX3 as markers of horse melanocytic cells. RACK1 emerges as an important marker of malignancy which may contribute to progress in the diagnosis of melanomas in both human and veterinary medicine.

RACK1, a clue to the diagnosis of cutaneous melanomas in horses

PubMed Central

2012-01-01

Background Melanocytic proliferations are common in horses but the diagnosis of malignancy is not always straightforward. To improve diagnosis and prognosis, markers of malignancy are needed. Receptor for activated C kinase 1 (RACK1) protein may be such a marker. RACK1 was originally found to characterize malignant melanocytic lesions in the Melanoblastoma-bearing Libechov minipig (MeLiM) and, later, in human patients. Our purpose was to investigate the value of RACK1 in the classification of cutaneous melanocytic proliferations in horses. Results Using immunofluorescence, we report here that both MITF (Microphthalmia-associated transcription factor) and PAX3 (Paired box 3) allow the identification of melanocytic cells in horse skin samples. Importantly, RACK1 was detected in melanocytic lesions but not in healthy skin melanocytes. Finally, we found that RACK1 labeling can be used in horses to distinguish benign melanocytic tumors from melanomas. Indeed, RACK1 labeling appeared more informative to assess malignancy than individual histomorphological features. Conclusions This study confirms that horses provide an interesting model for melanoma genesis studies. It establishes MITF and PAX3 as markers of horse melanocytic cells. RACK1 emerges as an important marker of malignancy which may contribute to progress in the diagnosis of melanomas in both human and veterinary medicine. PMID:22747534

Recalculation with SEACAB of the activation by spent fuel neutrons and residual dose originated in the racks replaced at Cofrentes NPP

NASA Astrophysics Data System (ADS)

Ortego, Pedro; Rodriguez, Alain; Töre, Candan; Compadre, José Luis de Diego; Quesada, Baltasar Rodriguez; Moreno, Raul Orive

2017-09-01

In order to increase the storage capacity of the East Spent Fuel Pool at the Cofrentes NPP, located in Valencia province, Spain, the existing storage stainless steel racks were replaced by a new design of compact borated stainless steel racks allowing a 65% increase in fuel storing capacity. Calculation of the activation of the used racks was successfully performed with the use of MCNP4B code. Additionally the dose rate at contact with a row of racks in standing position and behind a wall of shielding material has been calculated using MCNP4B code as well. These results allowed a preliminary definition of the burnker required for the storage of racks. Recently the activity in the racks has been recalculated with SEACAB system which combines the mesh tally of MCNP codes with the activation code ACAB, applying the rigorous two-step method (R2S) developed at home, benchmarked with FNG irradiation experiments and usually applied in fusion calculations for ITER project.

Putting EVM to the Test

NASA Technical Reports Server (NTRS)

Kerby, Jerald; Counts, Stacy

2005-01-01

IN MANY INSTANCES THERE IS NO FOREWARNING; SCHEDULES slip, costs soar, and the project manager is faced with the near impossible task of explaining why each impact occurred. With contractors performing the majority of the work, the management job can become even more obscure. The simple lack of proximity to the contractor can limit effective communication. Add to that a mixture of cultural differences and a desire for the contractor to portray the most optimistic view of their performance, and you create an even more difficult task for the project manager. This was the scenario when the Habitat Holding Rack (HHR) manager at Marshall Space Flight Center (MSFC), Stacy Counts, was introduced to the overall concept of Earned Value Management (EVM). Faced with increased costs (which eventually resulted in decreased scope of the project), continued schedule slides, and several technical anomalies, she was looking for a way to gain a better handle on the project performance. As a component of the Space Station Biological Research Program (SSBRP), the HHR project is an integral piece of the Program content. The HHR is the first rack hardware to be delivered for the Program and has therefore been the first rack to move through the trials of test and verification-documenting anomalies and technical difficulties that will benefit the other SSBRP rack projects. For these reasons, the HHR maintained high visibility throughout the manufacturing and assembly process, continuing through test and verification activities. Needless to say, the higher visibility emphasized the need for improved performance on this project. And to improve project performance, Stacy first had to figure out how to measure the cost, schedule and technical objectives effectively.

An Overview of the Microgravity Science Glovebox (MSG) Facility and the Research Performed in the MSG on the International Space Station (ISS)

NASA Technical Reports Server (NTRS)

Jordan, Lee P.

2013-01-01

The Microgravity Science Glovebox (MSG) is a rack facility aboard the International Space Station (ISS) designed for investigation handling. The MSG was built by the European Space Agency (ESA) which also provides sustaining engineering support for the facility. The MSG has been operating on the ISS since July 2002 and is currently located in the US Laboratory Module. The unique design of the facility allows it to accommodate science and technology investigations in a "workbench" type environment. The facility has an enclosed working volume that is held at a negative pressure with respect to the crew living area. This allows the facility to provide two levels of containment for small parts, particulates, fluids, and gases. This containment approach protects the crew from possible hazardous operations that take place inside the MSG work volume. Research investigations operating inside the MSG are provided a large 255 liter enclosed work space, 1000 watts of dc power via a versatile supply interface (120, 28, +/- 12, and 5 Vdc), 1000 watts of cooling capability, video and data recording and real time downlink, ground commanding capabilities, access to ISS Vacuum Exhaust and Vacuum Resource Systems, and gaseous nitrogen supply. These capabilities make the MSG one of the most utilized facilities on ISS. The MSG has been used for over 14500 hours of scientific payload operations. MSG investigations involve research in cryogenic fluid management, fluid physics, spacecraft fire safety, materials science, combustion, plant growth, and life support technology. The MSG facility is operated by the Payloads Operations Integration Center at Marshall Space flight Center. Payloads may also operate remotely from different telescience centers located in the United States and Europe. The investigative Payload Integration Manager (iPIM) is the focal to assist organizations that have payloads operating in the MSG facility. NASA provides an MSG engineering unit for payload developers to verify that their hardware is operating properly before actual operation on the ISS. This paper will provide an overview of the MSG facility, a synopsis of the research that has already been accomplished in the MSG, and an overview of video and biological upgrades.

RACK1-mediated translation control promotes liver fibrogenesis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, Min; Peng, Peike; Wang, Jiajun

Activation of quiescent hepatic stellate cells (HSCs) is the central event of liver fibrosis. The translational machinery is an optimized molecular network that affects cellular homoeostasis and diseases, whereas the role of protein translation in HSCs activation and liver fibrosis is little defined. Our previous report suggests that up-regulation of receptor for activated C-kinase 1(RACK1) in HSCs is critical for liver fibrogenesis. In this study, we found that RACK1 promoted macrophage conditioned medium (MCM)-induced assembly of eIF4F and phosphorylation of eIF4E in primary HSCs. RACK1 enhanced the translation and expression of pro-fibrogenic factors collagen 1α1, snail and cyclin E1 inducedmore » by MCM. Administration of PP242 or knock-down of eIF4E suppressed RACK1-stimulated collagen 1α1 production, proliferation and migration in primary HSCs. In addition, depletion of eIF4E attenuated thioacetamide (TAA)-induced liver fibrosis in vivo. Our data suggest that RACK1-mediated stimulation of cap-dependent translation plays crucial roles in HSCs activation and liver fibrogenesis, and targeting translation initiation could be a promising strategy for the treatment of liver fibrosis. - Highlights: • RACK1 induces the assembly of eIF4F and phosphorylation of eIF4E in primary HSCs. • RACK1 stimulates the translation of collagen 1α1, snail and cyclin E1 in HSCs. • RACK1 promotes HSCs activation via cap-mediated translation. • Depletion of eIF4E suppresses liver fibrogenesis in vivo.« less

Association of Mumps Virus V Protein with RACK1 Results in Dissociation of STAT-1 from the Alpha Interferon Receptor Complex

PubMed Central

Kubota, Toru; Yokosawa, Noriko; Yokota, Shin-ichi; Fujii, Nobuhiro

2002-01-01

It has been reported that mumps virus protein V or the C-terminal Cys-rich region of protein V (Vsp) is associated with blocking of the interferon (IFN) signal transduction pathway through a decrease in STAT-1 production. The intracellular target of the V protein was investigated by using a two-hybrid screening system with Vsp as bait. Full-length V protein and Vsp were able to bind to RACK1, and the interaction did not require two WD domains, WD1 and WD2, in RACK1. A significant interaction between V protein and RACK1 was also demonstrated in cells persistently infected with mumps virus (FLMT cells), and the formation of the complex was not affected by treatment with IFN. On the other hand, in uninfected cells, STAT-1 was associated with the long form of the β subunit of the alpha IFN receptor, and this association was mediated by the function of RACK1 as an adaptor protein. Immunoprecipitation and glutathione S-transferase pull-down experiments revealed that the association of RACK1 or mumps virus V protein with the IFN receptor was undetectable in mumps virus-infected cells. Furthermore, RACK1 interacted with mumps virus V protein with a higher affinity than STAT-1 did. Therefore, it is suggested that mumps virus V protein has the ability to interact strongly with RACK1 and consequently to bring about the disruption of the complex formed from STAT-1, RACK1, and the IFN receptor. PMID:12438593

Method and system for detecting explosives

DOEpatents

Reber, Edward L [Idaho Falls, ID; Jewell, James K [Idaho Falls, ID; Rohde, Kenneth W [Idaho Falls, ID; Seabury, Edward H [Idaho Falls, ID; Blackwood, Larry G [Idaho Falls, ID; Edwards, Andrew J [Idaho Falls, ID; Derr, Kurt W [Idaho Falls, ID

2009-03-10

A method of detecting explosives in a vehicle includes providing a first rack on one side of the vehicle, the rack including a neutron generator and a plurality of gamma ray detectors; providing a second rack on another side of the vehicle, the second rack including a neutron generator and a plurality of gamma ray detectors; providing a control system, remote from the first and second racks, coupled to the neutron generators and gamma ray detectors; using the control system, causing the neutron generators to generate neutrons; and performing gamma ray spectroscopy on spectra read by the gamma ray detectors to look for a signature indicative of presence of an explosive. Various apparatus and other methods are also provided.

Explosives detection system and method

DOEpatents

Reber, Edward L.; Jewell, James K.; Rohde, Kenneth W.; Seabury, Edward H.; Blackwood, Larry G.; Edwards, Andrew J.; Derr, Kurt W.

2007-12-11

A method of detecting explosives in a vehicle includes providing a first rack on one side of the vehicle, the rack including a neutron generator and a plurality of gamma ray detectors; providing a second rack on another side of the vehicle, the second rack including a neutron generator and a plurality of gamma ray detectors; providing a control system, remote from the first and second racks, coupled to the neutron generators and gamma ray detectors; using the control system, causing the neutron generators to generate neutrons; and performing gamma ray spectroscopy on spectra read by the gamma ray detectors to look for a signature indicative of presence of an explosive. Various apparatus and other methods are also provided.

Aircraft Enroute Command and Control Comms Redesign Mechanical Documentation

DTIC Science & Technology

2015-12-01

and power equipment is secured. Custom racks , with 8 server rack bays, are mounted to the pallet, with 2 desk stations for equipment operators...conventional rack equipment. Equipment in the original system was larger and heavier than the new equipment selected for the NG-JC2S. Battery backup was...purposes. The equipment also needed to be easily removable in the event of equipment failure. Surplus rack space available in the NG-JC2S system allowed

Activated protein kinase C binds to intracellular receptors in rat hepatocytes.

PubMed

Robles-Flores, M; García-Sáinz, J A

1993-12-01

The aim of this study was to identify in rat hepatocytes cellular polypeptides that bind protein kinase C (PKC) and may influence its activity and its compartmentation. At least seven proteins, with apparent M(r) values between 12,000 and 36,000, that behave like Receptors for Activated C-Kinase (RACKs) were found in the Triton-X-100-insoluble fraction of these cells; i.e. PKC bound to these polypeptides when it was in its active form. RACKS seem to be PKC substrates. Studies using isotype-specific PKC antibodies suggested some selectivity of RACKs, i.e. RACKs in the M(r) approximately 28,000-36,000 region bound PKC-alpha and PKC-beta in the presence of phosphatidylserine, diolein and Ca2+, whereas those of M(r) approximately 12,000-14,000 bound all isoforms studied, and, in contrast with the other RACKs, they did this even in the absence of Ca2+. Peptide I (KGDYEKILVALCGGN), which has a sequence suggested to be involved in the PKC-RACKs interaction [Mochly-Rosen, Khaner, Lopez and Smith (1991) J. Biol. Chem. 266, 14866-14868], inhibited PKC activity. Preincubation of RACKs with antisera directed against peptide I prevented PKC binding to them. The data suggest that peptide I blocks PKC binding to RACKs by two mechanisms: inhibition of PKC activity and competition with a putative binding site.

RACK1 interacts with filamin-A to regulate plasma membrane levels of the cystic fibrosis transmembrane conductance regulator

PubMed Central

Smith, Laura; Litman, Paul; Kohli, Ekta; Amick, Joseph; Page, Richard C.; Misra, Saurav

2013-01-01

Mutations in cystic fibrosis transmembrane regulator (CFTR), a chloride channel in the apical membranes of secretory epithelial cells, underlie the fatal genetic disorder cystic fibrosis. Certain CFTR mutations, including the common mutation ΔF508-CFTR, result in greatly decreased levels of active CFTR at the apical membrane. Direct interactions between CFTR and the cytoskeletal adaptors filamin-A (FlnA) and Na+/H+ exchanger regulatory factor 1 (NHERF1) stabilize the expression and localization of CFTR at the plasma membrane. The scaffold protein receptor for activated C kinase 1 (RACK1) also stabilizes CFTR surface expression; however, RACK1 does not interact directly with CFTR and its mechanism of action is unknown. In the present study, we report that RACK1 interacts directly with FlnA in vitro and in a Calu-3 airway epithelial cell line. We mapped the interaction between RACK1 and FlnA to the WD4 and WD6 repeats of RACK1 and to a segment of the large rod domain of FlnA, consisting of immunoglobulin-like repeats 8–15. Disruption of the RACK1-FlnA interaction causes a reduction in CFTR surface levels. Our results suggest that a novel RACK1-FlnA interaction is an important regulator of CFTR surface localization. PMID:23636454

U.S. Rep. Dave Weldon looks at the U.S. Lab Destiny in the SSPF.

NASA Technical Reports Server (NTRS)

1999-01-01

In the Space Station Processing Facility, U.S. Rep. Dave Weldon (center) and his chief of staff Dana Gartzke (second from left) get a close-up look at the interior of the U.S. Lab, called 'Destiny.' Thomas R. 'Randy' Galloway (second from right), with the Space Station Hardware Integration Office, helps with their familiarization of the equipment. They are joined (far left and right) by workers from Boeing. Weldon is on the House Science Committee and vice chairman of the Space and Aeronautics Subcommittee. Destiny is scheduled to be launched on Space Shuttle Endeavour in early 2000. It will become the centerpiece of scientific research on the ISS, with five equipment racks aboard to provide essential functions for station systems, including high data-rate communications, and to maintain the station's orientation using control gyroscopes launched earlier. Additional equipment and research racks will be installed in the laboratory on subsequent Shuttle flights.

Crewmember working on the spacelab Zeolite Crystal Growth experiment.

NASA Image and Video Library

1992-07-09

STS050-02-001 (9 July 1992) --- View showing Payload Specialists Bonnie Dunbar and Larry DeLucas in the aft section of the U. S. Microgravity Laboratory-1. Dunbar is preparing to load a sample in the Crystal Growth Furnace (CGF) Integrated Furnace Experiment Assembly (IFEA) in rack 9 of the Microgravity Laboratory. DeLucas is checking out the multipurpose Glovebox Facility.

Improvements in analysis techniques for segmented mirror arrays

NASA Astrophysics Data System (ADS)

Michels, Gregory J.; Genberg, Victor L.; Bisson, Gary R.

2016-08-01

The employment of actively controlled segmented mirror architectures has become increasingly common in the development of current astronomical telescopes. Optomechanical analysis of such hardware presents unique issues compared to that of monolithic mirror designs. The work presented here is a review of current capabilities and improvements in the methodology of the analysis of mechanically induced surface deformation of such systems. The recent improvements include capability to differentiate surface deformation at the array and segment level. This differentiation allowing surface deformation analysis at each individual segment level offers useful insight into the mechanical behavior of the segments that is unavailable by analysis solely at the parent array level. In addition, capability to characterize the full displacement vector deformation of collections of points allows analysis of mechanical disturbance predictions of assembly interfaces relative to other assembly interfaces. This capability, called racking analysis, allows engineers to develop designs for segment-to-segment phasing performance in assembly integration, 0g release, and thermal stability of operation. The performance predicted by racking has the advantage of being comparable to the measurements used in assembly of hardware. Approaches to all of the above issues are presented and demonstrated by example with SigFit, a commercially available tool integrating mechanical analysis with optical analysis.

International Space Station (ISS)

NASA Image and Video Library

2001-03-11

STS-102 mission astronaut Susan J. Helms works outside the International Space Station (ISS) while holding onto a rigid umbilical and her feet anchored to the Remote Manipulator System (RMS) robotic arm on the Space Shuttle Discovery during the first of two space walks. During this space walk, the longest to date in space shuttle history, Helms in tandem with James S. Voss (out of frame), prepared the Pressurized Mating Adapter 3 for repositioning from the Unity Module's Earth-facing berth to its port-side berth to make room for the Leonardo Multipurpose Logistics Module (MPLM) supplied by the Italian Space Agency. The Leonardo MPLM is the first of three such pressurized modules that will serve as the ISS's moving vans, carrying laboratory racks filled with equipment, experiments, and supplies to and from the Station aboard the Space Shuttle. The cylindrical module is approximately 21-feet long and 15- feet in diameter, weighing almost 4.5 tons. It can carry up to 10 tons of cargo in 16 standard Space Station equipment racks. Of the 16 racks the module can carry, 5 can be furnished with power, data, and fluid to support refrigerators or freezers. In order to function as an attached station module as well as a cargo transport, the logistics module also includes components that provide life support, fire detection and suppression, electrical distribution, and computer functions. Launched on May 8, 2001 for nearly 13 days in space, STS-102 mission was the 8th spacecraft assembly flight to the ISS and NASA's 103rd overall mission. The mission also served as a crew rotation flight. It delivered the Expedition Two crew to the Station and returned the Expedition One crew back to Earth.

International Space Station (ISS)

NASA Image and Video Library

2001-03-11

STS-102 astronaut and mission specialist James S. Voss works outside Destiny, the U.S. Laboratory (shown in lower frame) on the International Space Station (ISS), while anchored to the Remote Manipulator System (RMS) robotic arm on the Space Shuttle Discovery during the first of two space walks. During this space walk, the longest to date in space shuttle history, Voss in tandem with Susan Helms (out of frame), prepared the Pressurized Mating Adapter 3 for repositioning from the Unity Module's Earth-facing berth to its port-side berth to make room for the Leonardo Multipurpose Logistics Module (MPLM) supplied by the Italian Space Agency. The The Leonardo MPLM is the first of three such pressurized modules that will serve as the ISS' moving vans, carrying laboratory racks filled with equipment, experiments, and supplies to and from the Station aboard the Space Shuttle. The cylindrical module is approximately 21-feet long and 15- feet in diameter, weighing almost 4.5 tons. It can carry up to 10 tons of cargo in 16 standard Space Station equipment racks. Of the 16 racks the module can carry, 5 can be furnished with power, data, and fluid to support refrigerators or freezers. In order to function as an attached station module as well as a cargo transport, the logistics module also includes components that provide life support, fire detection and suppression, electrical distribution, and computer functions. Launched on May 8, 2001 for nearly 13 days in space, the STS-102 mission was the 8th spacecraft assembly flight to the ISS and NASA's 103rd overall mission. The mission also served as a crew rotation flight. It delivered the Expedition Two crew to the Station and returned the Expedition One crew back to Earth.

STS-102 Astronaut James Voss Participates in Space Walk

NASA Technical Reports Server (NTRS)

2001-01-01

STS-102 astronaut and mission specialist James S. Voss works outside Destiny, the U.S. Laboratory (shown in lower frame) on the International Space Station (ISS), while anchored to the Remote Manipulator System (RMS) robotic arm on the Space Shuttle Discovery during the first of two space walks. During this space walk, the longest to date in space shuttle history, Voss in tandem with Susan Helms (out of frame), prepared the Pressurized Mating Adapter 3 for repositioning from the Unity Module's Earth-facing berth to its port-side berth to make room for the Leonardo Multipurpose Logistics Module (MPLM) supplied by the Italian Space Agency. The The Leonardo MPLM is the first of three such pressurized modules that will serve as the ISS' moving vans, carrying laboratory racks filled with equipment, experiments, and supplies to and from the Station aboard the Space Shuttle. The cylindrical module is approximately 21-feet long and 15- feet in diameter, weighing almost 4.5 tons. It can carry up to 10 tons of cargo in 16 standard Space Station equipment racks. Of the 16 racks the module can carry, 5 can be furnished with power, data, and fluid to support refrigerators or freezers. In order to function as an attached station module as well as a cargo transport, the logistics module also includes components that provide life support, fire detection and suppression, electrical distribution, and computer functions. Launched on May 8, 2001 for nearly 13 days in space, the STS-102 mission was the 8th spacecraft assembly flight to the ISS and NASA's 103rd overall mission. The mission also served as a crew rotation flight. It delivered the Expedition Two crew to the Station and returned the Expedition One crew back to Earth.

STS-102 Astronaut Susan Helms Participates in Space Walk

NASA Technical Reports Server (NTRS)

2001-01-01

STS-102 mission astronaut Susan J. Helms works outside the International Space Station (ISS) while holding onto a rigid umbilical and her feet anchored to the Remote Manipulator System (RMS) robotic arm on the Space Shuttle Discovery during the first of two space walks. During this space walk, the longest to date in space shuttle history, Helms in tandem with James S. Voss (out of frame), prepared the Pressurized Mating Adapter 3 for repositioning from the Unity Module's Earth-facing berth to its port-side berth to make room for the Leonardo Multipurpose Logistics Module (MPLM) supplied by the Italian Space Agency. The Leonardo MPLM is the first of three such pressurized modules that will serve as the ISS's moving vans, carrying laboratory racks filled with equipment, experiments, and supplies to and from the Station aboard the Space Shuttle. The cylindrical module is approximately 21-feet long and 15- feet in diameter, weighing almost 4.5 tons. It can carry up to 10 tons of cargo in 16 standard Space Station equipment racks. Of the 16 racks the module can carry, 5 can be furnished with power, data, and fluid to support refrigerators or freezers. In order to function as an attached station module as well as a cargo transport, the logistics module also includes components that provide life support, fire detection and suppression, electrical distribution, and computer functions. Launched on May 8, 2001 for nearly 13 days in space, STS-102 mission was the 8th spacecraft assembly flight to the ISS and NASA's 103rd overall mission. The mission also served as a crew rotation flight. It delivered the Expedition Two crew to the Station and returned the Expedition One crew back to Earth.

RESOLVE 2010 Field Test

NASA Technical Reports Server (NTRS)

Captain, J.; Quinn, J.; Moss, T.; Weis, K.

2010-01-01

This slide presentation reviews the field tests conducted in 2010 of the Regolith Environment Science & Oxygen & Lunar Volatile Extraction (RESOLVE). The Resolve program consist of several mechanism: (1) Excavation and Bulk Regolith Characterization (EBRC) which is designed to act as a drill and crusher, (2) Regolith Volatiles Characterization (RVC) which is a reactor and does gas analysis,(3) Lunar Water Resources Demonstration (LWRD) which is a fluid system, water and hydrogen capture device and (4) the Rover. The scientific goal of this test is to demonstrate evolution of low levels of hydrogen and water as a function of temperature. The Engineering goals of this test are to demonstrate:(1) Integration onto new rover (2) Miniaturization of electronics rack (3) Operation from battery packs (elimination of generator) (4) Remote command/control and (5) Operation while roving. Views of the 2008 and the 2010 mechanisms, a overhead view of the mission path, a view of the terrain, the two drill sites, and a graphic of the Master Events Controller Graphical User Interface (MEC GUI) are shown. There are descriptions of the Gas chromatography (GC), the operational procedure, water and hydrogen doping of tephra. There is also a review of some of the results, and future direction for research and tests.

Sensor Network Demonstration for In Situ Decommissioning - 13332

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lagos, L.; Varona, J.; Awwad, A.

2013-07-01

Florida International University's (FIU's) Applied Research Center is currently supporting the Department of Energy's (DOE) Environmental Management Office of D and D and Facility Engineering program. FIU is supporting DOE's initiative to improve safety, reduce technical risks, and limit uncertainty within D and D operations by identifying technologies suitable to meet specific facility D and D requirements, assessing the readiness of those technologies for field deployment, and conducting feasibility studies and large scale demonstrations of promising technologies. During FY11, FIU collaborated with Savannah River National Laboratory in the development of an experimental test site for the demonstration of multiple sensormore » systems for potential use in the in situ decommissioning process. In situ decommissioning is a process in which the above ground portion of a facility is dismantled and removed, and the underground portion is filled with a cementious material such as grout. In such a scenario, the question remains on how to effectively monitor the structural health of the grout (cracking, flexing, and sinking), as well as track possible migration of contaminants within and out of the grouted monolith. The right types of sensors can aid personnel in better understanding the conditions within the entombed structure. Without sensors embedded in and around the monolith, it will be very difficult to estimate structural integrity and contaminant transport. Yet, to fully utilize the appropriate sensors and the provided data, their performance and reliability must be evaluated outside a laboratory setting. To this end, a large scale experimental setup and demonstration was conducted at FIU. In order to evaluate a large suite of sensor systems, FIU personnel designed and purchased a pre-cast concrete open-top cube, which served as a mock-up of an in situ DOE decommissioned facility. The inside of the cube measures 10 ft x 10 ft x 8 ft. In order to ensure that the individual sensors would be immobilized during the grout pouring activities, a set of nine sensor racks were designed. The 270 sensors provided by Idaho National Laboratory (INL), Mississippi State University (MSU), University of Houston (UH), and University of South Carolina (USC) were secured to these racks based on predetermined locations. Once sensor racks were installed inside the test cube, connected and debugged, approximately 32 cubic yards of special grout material was used to entomb the sensors. MSU provided and demonstrated four types of fiber loop ring-down (FLR) sensors for detection of water, temperature, cracks, and movement of fluids. INL provided and demonstrated time differenced 3D electrical resistivity tomography (ERT), advanced tensiometers for moisture content, and thermocouples for temperature measurements. University of Houston provided smart aggregate (SA) sensors, which detect crack severity and water presence. An additional UH sensor system demonstrated was a Fiber Bragg Grating (FBG) fiber optic system measuring strain, presence of water, and temperature. USC provided a system which measured acoustic emissions during cracking, as well as temperature and pH sensors. All systems were connected to a Sensor Remote Access System (SRAS) data networking and collection system designed, developed and provided by FIU. The purpose of SRAS was to collect and allow download of the raw sensor data from all the sensor system, as well as allow upload of the processed data and any analysis reports and graphs. All this information was made available to the research teams via the Deactivation and Decommissioning Knowledge Management and Information Tool (D and D KM-IT). As a current research effort, FIU is performing an energy analysis, and transferring several sensor systems to a Photovoltaic (PV) System to continuously monitor energy consumption parameters and overall power demands. Also, One final component of this research is focusing on developing an integrated data network to capture, log and analyze sensor system data in near real time from a single interface. FIU personnel and DOE Fellows monitored the progress and condition of the sensors for a period of six months. During this time, the sensors recorded data pertaining to strain, compression, temperature, crack detection, moisture presence, fluid mobility, shock resistance, monolith movement, and electrical resistivity. In addition, FIU regularly observed the curing process of the grout and documented the cube condition via the nine racks of sensors. The sensors held up throughout the curing process, withstood the natural elements for six months, and monitored the integrity of the grout. The large scale experiment and demonstration conducted at FIU was the first of its kind to demonstrate the feasibility of state of the art sensors for in situ decommissioning applications. These efforts successfully measured the durability, performance, and precision of the sensors in question as well as monitored and recorded the curing process of the selected grout material under natural environmental conditions. The current energy analysis work is resulting in data on the constraints placed by some of the sensor systems on a power network that requires high reliability and low losses. In addition, a sensor system demonstration has determined that it is feasible to develop an integrated data network where data can be accessed in near real-time from all systems, thereby allowing for larger-scale integrated system testing to be performed. Information collected during the execution of this research project will aid decision makers in the identification of sensors to be used in nuclear facilities selected for in situ decommissioning. (authors)« less

Transcription analysis in the MeLiM swine model identifies RACK1 as a potential marker of malignancy for human melanocytic proliferation.

PubMed

Egidy, Giorgia; Julé, Sophia; Bossé, Philippe; Bernex, Florence; Geffrotin, Claudine; Vincent-Naulleau, Silvia; Horak, Vratislav; Sastre-Garau, Xavier; Panthier, Jean-Jacques

2008-04-28

Metastatic melanoma is a severe disease. Few experimental animal models of metastatic melanoma exist. MeLiM minipigs exhibit spontaneous melanoma. Cutaneous and metastatic lesions are histologically similar to human's. However, most of them eventually spontaneously regress. Our purpose was to investigate whether the MeLiM model could reveal markers of malignancy in human melanocytic proliferations. We compared the serial analysis of gene expression (SAGE) between normal pig skin melanocytes and melanoma cells from an early pulmonary metastasis of MeLiM minipigs. Tag identification revealed 55 regulated genes, including GNB2L1 which was found upregulated in the melanoma library. In situ hybridisation confirmed GNB2L1 overexpression in MeLiM melanocytic lesions. GNB2L1 encodes the adaptor protein RACK1, recently shown to influence melanoma cell lines tumorigenicity. We studied the expression of RACK1 by immunofluorescence and confocal microscopy in tissues specimens of normal skin, in cutaneous and metastatic melanoma developped in MeLiM minipigs and in human patients. In pig and human samples, the results were similar. RACK1 protein was not detected in normal epidermal melanocytes. By contrast, RACK1 signal was highly increased in the cytoplasm of all melanocytic cells of superficial spreading melanoma, recurrent dermal lesions and metastatic melanoma. RACK1 partially colocalised with activated PKCalphabeta. In pig metastases, additional nuclear RACK1 did not associate to BDNF expression. In human nevi, the RACK1 signal was low. RACK1 overexpression detected in situ in human melanoma specimens characterized cutaneous and metastatic melanoma raising the possibility that RACK1 can be a potential marker of malignancy in human melanoma. The MeLiM strain provides a relevant model for exploring mechanisms of melanocytic malignant transformation in humans. This study may contribute to a better understanding of melanoma pathophysiology and to progress in diagnosis.

Transcription analysis in the MeLiM swine model identifies RACK1 as a potential marker of malignancy for human melanocytic proliferation

PubMed Central

Egidy, Giorgia; Julé, Sophia; Bossé, Philippe; Bernex, Florence; Geffrotin, Claudine; Vincent-Naulleau, Silvia; Horak, Vratislav; Sastre-Garau, Xavier; Panthier, Jean-Jacques

2008-01-01

Background Metastatic melanoma is a severe disease. Few experimental animal models of metastatic melanoma exist. MeLiM minipigs exhibit spontaneous melanoma. Cutaneous and metastatic lesions are histologically similar to human's. However, most of them eventually spontaneously regress. Our purpose was to investigate whether the MeLiM model could reveal markers of malignancy in human melanocytic proliferations. Results We compared the serial analysis of gene expression (SAGE) between normal pig skin melanocytes and melanoma cells from an early pulmonary metastasis of MeLiM minipigs. Tag identification revealed 55 regulated genes, including GNB2L1 which was found upregulated in the melanoma library. In situ hybridisation confirmed GNB2L1 overexpression in MeLiM melanocytic lesions. GNB2L1 encodes the adaptor protein RACK1, recently shown to influence melanoma cell lines tumorigenicity. We studied the expression of RACK1 by immunofluorescence and confocal microscopy in tissues specimens of normal skin, in cutaneous and metastatic melanoma developped in MeLiM minipigs and in human patients. In pig and human samples, the results were similar. RACK1 protein was not detected in normal epidermal melanocytes. By contrast, RACK1 signal was highly increased in the cytoplasm of all melanocytic cells of superficial spreading melanoma, recurrent dermal lesions and metastatic melanoma. RACK1 partially colocalised with activated PKCαβ. In pig metastases, additional nuclear RACK1 did not associate to BDNF expression. In human nevi, the RACK1 signal was low. Conclusion RACK1 overexpression detected in situ in human melanoma specimens characterized cutaneous and metastatic melanoma raising the possibility that RACK1 can be a potential marker of malignancy in human melanoma. The MeLiM strain provides a relevant model for exploring mechanisms of melanocytic malignant transformation in humans. This study may contribute to a better understanding of melanoma pathophysiology and to progress in diagnosis. PMID:18442364

Habitat use by Red Knots (Calidris canutus rufa): Experiments with oyster racks and reefs on the beach and intertidal of Delaware Bay, New Jersey

NASA Astrophysics Data System (ADS)

Burger, Joanna; Niles, Lawrence J.

2017-07-01

Sea level rise and increasing human activities have decreased intertidal habitat in many places in the world. The expansion of aquaculture in intertidal areas may impact birds and other organisms using these habitats, leading to questions of sustainability of both aquaculture and functioning estuarine ecosystems. Understanding the effect of oyster culture on shorebird activity, particularly on Red Knots (Calidris canutus rufa), a species on the U.S. Threatened List, is important for adaptive management and the expansion of oyster culture. In May 2013 we experimentally compared Red Knot and shorebird use of a beach section with racks and a control, and in 2016 we compared the use of sections with artificial reefs, oyster racks, and control on Delaware Bay, New Jersey (USA). The data included only times when no workers or other people were present. Censuses, conducted every 30 min throughout the day (279 censuses in 2013, 231 censuses in 2016), included the number of Red Knots and other shorebirds in each treatment section. In 2013, the total number of shorebirds was significantly higher in the rack section than in the control section, except for Red Knots and Ruddy Turnstones (Arenaria interpres) that occurred in higher numbers in the control than in the rack section. In 2016 Red Knot numbers were also significantly lower in the rack section. In 2013, the mean number of Red Knots/census was 13 for racks vs 59 for the control (P < 0.0002). In 2016, the mean number of Red Knots/census was 13 for racks and over 68 for other treatments (P < 0.0001). Treatment, date, and number of non-Knot shorebirds explained 60% (2013) and 69% (2016) of the variation in Red Knot numbers. Red Knots avoided the sections with racks while both foraging and roosting, suggesting that caution should be used before placing oyster racks in areas used for foraging by Red Knots.

Investigation of flow in data rack

NASA Astrophysics Data System (ADS)

Manoch, Lukáš; Nožička, Jiří; Pohan, Petr

2012-04-01

The main purpose of this paper was to set up a functioning numerical model of data rack verified by an experimental measurement. The verification of the numerical model was carried out by means of the PIV method (Particle Image Velocimetry). The numerical model was "found" while using the assumed and preset values from the experimental measurement which represent boundary conditions. The server model was conceived as a four-channel with a controlled flow rate without simulation of heat transfer. The flow rate in each channel was implemented by means of pressure loss. The numerical model was further used for simulation of several phases and configurations of data rack (21U rack space) fitted with two server workstations Dell Precision R5400. The flow field in the inlet of data rack in the front of the workstations were observed and evaluated in such a way that a 2U-dimensional free space between the workstations was being left and the remaining inlet space was blanked-off/fully opened. The results of this paper will serve for designing optimization treatment of data rack from the viewpoint of cooling efficiency both within the data rack and within the data center design.

EXPRESS Rack Technology for Space Station

NASA Technical Reports Server (NTRS)

Davis, Ted B.; Adams, J. Brian; Fisher, Edward M., Jr.; Prickett, Guy B.; Smith, Timothy G.

1999-01-01

The EXPRESS rack provides accommodations for standard Mid-deck Locker and ISIS drawer payloads on the International Space Station. A design overview of the basic EXPRESS rack and two derivatives, the Human Research Facility and the Habitat Holding Rack, is given in Part I. In Part II, the design of the Solid State Power Control Module (SSPCM) is reviewed. The SSPCM is a programmable and remotely controllable power switching and voltage conversion unit which distributes and protects up to 3kW of 12OVDC and 28VDC power to payloads and rack subsystem components. Part III details the development and testing of a new data storage device, the BRP EXPRESS Memory Unit (BEMU). The BEMU is a conduction-cooled device which operates on 28VDC and is based on Boeing-modified 9GB commercial disk-drive technology. In Part IV results of a preliminary design effort for a rack Passive Damping System (PDS) are reported. The PDS is intended to isolate ISPR-based experiment racks from on-orbit vibration. System performance predictions based on component developmental testing indicate that such a system can provide effective isolation at frequencies of 1 Hz and above.

RACK1 forms a complex with FGFR1 and PKM2, and stimulates the growth and migration of squamous lung cancer cells.

PubMed

Zhou, Chengzhi; Chen, Tao; Xie, Zhanhong; Qin, Yinyin; Ou, Yangming; Zhang, Jiexia; Li, Shiyue; Chen, Rongchang; Zhong, Nanshan

2017-11-01

Phosphorylation of Pyruvate Kinase M2 (PKM2) on Tyr105 by fibroblast growth factor receptor 1 (FGFR1) has been shown to promote its nuclear localization as well as cell growth in lung cancer. Better understanding the regulation of this process would benefit the clinical treatment for lung cancer. Here, it has been found that the adaptor protein receptor for activated PKC kinase (RACK1) formed a complex with FGFR1 and PKM2, and activated the FGFR1/PKM2 signaling. Knocking down the expression of RACK1 impaired the phosphorylation on Tyr105 of PKM2 and inhibited the growth and migration of lung cancer cells, while over-expression of RACK1 in lung cancer cells led to the resistance to Erdafitinib. Moreover, knocking down the expression of RACK1 impaired the tumorigenesis of lung cancer driven by LKB loss and mutated Ras (KrasG12D). Taken together, our study demonstrated the pivotal roles of RACK1 in FGFR1/PKM2 signaling, suggesting FGFR1/RACK1/PKM2 might be a therapeutic target for lung cancer treatment. © 2017 Wiley Periodicals, Inc.

40 CFR 63.1105 - Transfer racks.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 10 2010-07-01 2010-07-01 false Transfer racks. 63.1105 Section 63.1105 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED... Technology Standards § 63.1105 Transfer racks. (a) Design requirements. The owner or operator shall equip...

Casimir rack and pinion as a miniaturized kinetic energy harvester

NASA Astrophysics Data System (ADS)

Miri, MirFaez; Etesami, Zahra

2016-08-01

We study a nanoscale machine composed of a rack and a pinion with no contact, but intermeshed via the lateral Casimir force. We adopt a simple model for the random velocity of the rack subject to external random forces, namely, a dichotomous noise with zero mean value. We show that the pinion, even when it experiences random thermal torque, can do work against a load. The device thus converts the kinetic energy of the random motions of the rack into useful work.

Survey view of EXPRESS Rack 4 in the JPM during Expedition 22

NASA Image and Video Library

2009-12-30

iss022e015850 (12/30/2009) --- The image shows a front view of EXpedite the PRocessing of Experiments to Space Station EXPRESS Rack 4 (Rack 4,JPM/1F5) in the Japanese Experiment Module (JEM) Japanese Pressurized Module (JPM). Equipment visible in the EXPRESS Rack includes the Biotechnology Specimen Temperature Controller (BSTC) and the Gas Supply Module (GSM) support hardware for the CBOSS (Cellular Biotechnology Operations Support Systems) investigations, and the Device for the Study of Critical Liquids and Crystallization (DECLIC).

Surveillance of a Ventilated Rack System for Corynebacterium bovis by Sampling Exhaust-Air Manifolds.

PubMed

Manuel, Christopher A; Pugazhenthi, Umarani; Leszczynski, Jori K

2016-01-01

Corynebacterium bovis causes an opportunistic infection of nude (Foxn1, nu/nu) mice, leading to nude mouse hyperkeratotic dermatitis (scaly skin disease). Enzootic in many nude mouse colonies, C. bovis spreads rapidly to naive nude mice, despite modern husbandry practices, and is very difficult to eradicate. To facilitate rapid detection in support of eradication efforts, we investigated a surveillance method based on quantitative real-time PCR (qPCR) evaluation of swabs collected from the horizontal exhaust manifold (HEM) of an IVC rack system. We first evaluated the efficacy of rack sanitation methods for removing C. bovis DNA from the HEM of racks housing endemic colonies of infected nude mice. Pressurized water used to flush the racks' air exhaust system followed by a standard rack-washer cycle was ineffective in eliminating C. bovis DNA. Only after autoclaving did all sanitized racks test negative for C. bovis DNA. We then measured the effects of stage of infection (early or established), cage density, and cage location on the rack on time-to-detection at the HEM. Stage of infection significantly affected time-to-detection, independent of cage location. Early infections required 7.3 ± 1.2 d whereas established infections required 1 ± 0 d for detection of C. bovis at the HEM. Cage density influenced the quantity of C. bovis DNA detected but not time-to-detection. The location of the cage on the rack affected the time-to-detection only during early C. bovis infections. We suggest that qPCR swabs of HEM are useful during the routine surveillance of nude mouse colonies for C. bovis infection.

Phospholipase C-gamma 1 binding to intracellular receptors for activated protein kinase C.

PubMed

Disatnik, M H; Hernandez-Sotomayor, S M; Jones, G; Carpenter, G; Mochly-Rosen, D

1994-01-18

Phospholipase C-gamma 1 (PLC-gamma 1; EC 3.1.4.11) hydrolyzes phosphatidylinositol 4,5-bisphosphate to generate diacylglycerol and inositol 1,4,5-trisphosphate and is activated in response to growth factor stimulation and tyrosine phosphorylation. Concomitantly, the enzyme translocates from the cytosol to the particulate cell fraction. A similar process of activation-induced translocation from the cytosol to the cell particulate fraction has also been described for protein kinase C (PKC). We have previously shown that activated PKC binds to specific receptor proteins, receptors for activated C kinase, or RACKs, of approximately 30 kDa. Here, we show that PLC-gamma 1 bound to these RACKs and inhibited subsequent PKC binding to RACKs. However, unlike PKC, the binding of PLC-gamma 1 to RACKs did not require phospholipids and calcium. After epidermal growth factor treatment of intact A-431 cells, the binding of PLC-gamma 1 to RACKs increased as compared with PLC-gamma 1 from control cells. This increase in PLC-gamma 1 binding to RACKs was due to the phosphorylation of PLC-gamma 1. Additional data indicated that PLC-gamma 1 binds to RACKs in solution; epidermal growth factor receptor-dependent PLC-gamma 1 phosphorylation and activation decreased in the presence of RACKs. It is possible that, in vivo, PLC-gamma 1 associates with RACKs or with other PLC-gamma 1-specific anchoring proteins in the particulate cell fraction. Since a PKC C2 homologous region is present in PLC-gamma 1, the C2 region may mediate the activation-induced translocation of the enzyme to the cell particulate fraction and the anchoring protein-PLC-gamma 1 complex may be the active translocated form of PLC-gamma 1.

The scaffold protein RACK1 is a target of endocrine disrupting chemicals (EDCs) with important implication in immunity

DOE Office of Scientific and Technical Information (OSTI.GOV)

Buoso, Erica; Galasso, Marilisa; Ronfani, Melania

We recently demonstrated the existence of a complex hormonal balance between steroid hormones in the control of RACK1 (Receptor for Activated C Kinase 1) expression and immune activation, suggesting that this scaffold protein may also be targeted by endocrine disrupting chemicals (EDCs). As a proof of concept, we investigated the effect of the doping agent nandrolone, an androgen receptor (AR) agonist, and of p,p′DDT (dichlorodiphenyltrichloroethane) and its main metabolite p,p′DDE (dichlorodiphenyldichloroethylene), a weak and strong AR antagonist, respectively, on RACK1 expression and innate immune response. In analogy to endogenous androgens, nandrolone induced a dose-related increase in RACK1 transcriptional activity andmore » protein expression, resulting in increased LPS-induced IL-8 and TNF-α production and proliferation in THP-1 cells. Conversely, p,p′DDT and p,p′DDE significantly decrease RACK1 expression, LPS-induced cytokine production and CD86 expression; with p,p′DDE exerting a stronger repressor effect than p,p′DDT, consistent with its stronger AR antagonistic effect. These results indicate that RACK1 could be a relevant target of EDCs, responding in opposite ways to agonist or antagonist of AR, representing a bridge between the endocrine system and the innate immune system. - Highlights: • RACK1 expression can be induced by AR agonists with a consequent enhancement of the response to LPS. • RACK1 can be negatively modulated by the AR antagonists DDT and its main metabolite p,p′DDE. • RACK1 can be a relevant target of EDCs, representing a bridge between the endocrine system and the immune system.« less

40 CFR 63.650 - Gasoline loading rack provisions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 10 2011-07-01 2011-07-01 false Gasoline loading rack provisions. 63...) National Emission Standards for Hazardous Air Pollutants From Petroleum Refineries § 63.650 Gasoline... or operator of a Group 1 gasoline loading rack classified under Standard Industrial Classification...

40 CFR 63.650 - Gasoline loading rack provisions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 10 2010-07-01 2010-07-01 false Gasoline loading rack provisions. 63...) National Emission Standards for Hazardous Air Pollutants From Petroleum Refineries § 63.650 Gasoline... or operator of a Group 1 gasoline loading rack classified under Standard Industrial Classification...

40 CFR 63.650 - Gasoline loading rack provisions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 11 2012-07-01 2012-07-01 false Gasoline loading rack provisions. 63...) National Emission Standards for Hazardous Air Pollutants From Petroleum Refineries § 63.650 Gasoline... or operator of a Group 1 gasoline loading rack classified under Standard Industrial Classification...

40 CFR 63.650 - Gasoline loading rack provisions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 11 2013-07-01 2013-07-01 false Gasoline loading rack provisions. 63...) National Emission Standards for Hazardous Air Pollutants From Petroleum Refineries § 63.650 Gasoline... or operator of a Group 1 gasoline loading rack classified under Standard Industrial Classification...

40 CFR 63.650 - Gasoline loading rack provisions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 11 2014-07-01 2014-07-01 false Gasoline loading rack provisions. 63...) National Emission Standards for Hazardous Air Pollutants From Petroleum Refineries § 63.650 Gasoline... or operator of a Group 1 gasoline loading rack classified under Standard Industrial Classification...

40 CFR 65.142 - Standards.

Code of Federal Regulations, 2010 CFR

2010-07-01

... of this subpart apply to Group 2A process vents. (c) Transfer rack requirements. The owner or... route transfer rack emissions through a closed vent system to a flare shall meet the applicable... requirements referenced therein. No other provisions of this subpart apply to transfer rack emissions routed...

40 CFR 65.166 - Periodic reports.

Code of Federal Regulations, 2010 CFR

2010-07-01

..., including a halogen reduction device for a low-throughput transfer rack, is used to control emissions from storage vessels or low-throughput transfer racks, the periodic report shall identify and state the cause...-throughput transfer racks, periodic reports shall include the following information: (1) Periodic reports...

Loss of the starvation-induced gene Rack1 leads to glycogen deficiency and impaired autophagic responses in Drosophila.

PubMed

Erdi, Balázs; Nagy, Péter; Zvara, Agnes; Varga, Agnes; Pircs, Karolina; Ménesi, Dalma; Puskás, László G; Juhász, Gábor

2012-07-01

Autophagy delivers cytoplasmic material for lysosomal degradation in eukaryotic cells. Starvation induces high levels of autophagy to promote survival in the lack of nutrients. We compared genome-wide transcriptional profiles of fed and starved control, autophagy-deficient Atg7 and Atg1 null mutant Drosophila larvae to search for novel regulators of autophagy. Genes involved in catabolic processes including autophagy were transcriptionally upregulated in all cases. We also detected repression of genes involved in DNA replication in autophagy mutants compared with control animals. The expression of Rack1 (receptor of activated protein kinase C 1) increased 4.1- to 5.5-fold during nutrient deprivation in all three genotypes. The scaffold protein Rack1 plays a role in a wide range of processes including translation, cell adhesion and migration, cell survival and cancer. Loss of Rack1 led to attenuated autophagic response to starvation, and glycogen stores were decreased 11.8-fold in Rack1 mutant cells. Endogenous Rack1 partially colocalized with GFP-Atg8a and early autophagic structures on the ultrastructural level, suggesting its involvement in autophagosome formation. Endogenous Rack1 also showed a high degree of colocalization with glycogen particles in the larval fat body, and with Shaggy, the Drosophila homolog of glycogen synthase kinase 3B (GSK-3B). Our results, for the first time, demonstrated the fundamental role of Rack1 in autophagy and glycogen synthesis.

Semi-automated 96-well liquid-liquid extraction for quantitation of drugs in biological fluids.

PubMed

Zhang, N; Hoffman, K L; Li, W; Rossi, D T

2000-02-01

A semi-automated liquid-liquid extraction (LLE) technique for biological fluid sample preparation was introduced for the quantitation of four drugs in rat plasma. All liquid transferring during the sample preparation was automated using a Tomtec Quadra 96 Model 320 liquid handling robot, which processed up to 96 samples in parallel. The samples were either in 96-deep-well plate or tube-rack format. One plate of samples can be prepared in approximately 1.5 h, and the 96-well plate is directly compatible with the autosampler of an LC/MS system. Selection of organic solvents and recoveries are discussed. Also, precision, relative error, linearity and quantitation of the semi automated LLE method are estimated for four example drugs using LC/MS/MS with a multiple reaction monitoring (MRM) approach. The applicability of this method and future directions are evaluated.

41. Upper level, electronic racks, left to rightprogrammer group, status ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

41. Upper level, electronic racks, left to right--programmer group, status command message processing group, UHF radio, impss rack security - Ellsworth Air Force Base, Delta Flight, Launch Facility, On County Road T512, south of Exit 116 off I-90, Interior, Jackson County, SD

10 CFR 36.35 - Source rack protection.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 1 2011-01-01 2011-01-01 false Source rack protection. 36.35 Section 36.35 Energy NUCLEAR REGULATORY COMMISSION LICENSES AND RADIATION SAFETY REQUIREMENTS FOR IRRADIATORS Design and Performance... guides to prevent products and product carriers from hitting or touching the rack or mechanism. ...

16 CFR Figure 3 to Part 1610 - Specimen Holder Supported in Specimen Rack

Code of Federal Regulations, 2010 CFR

2010-01-01

... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Specimen Holder Supported in Specimen Rack 3 Figure 3 to Part 1610 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION FLAMMABLE FABRICS ACT... Holder Supported in Specimen Rack ER25MR08.002 ...

42. Upper level, electronic racks, left to rightguidance and control ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

42. Upper level, electronic racks, left to right--guidance and control coupler rack, programmer group, status command message processing group, UHF radio - Ellsworth Air Force Base, Delta Flight, Launch Facility, On County Road T512, south of Exit 116 off I-90, Interior, Jackson County, SD

The fabrication of plastic cages for suspension in mass air flow racks.

PubMed

Nielsen, F H; Bailey, B

1979-08-01

A cage for suspension in mass air flow racks was constructed of plastic and used to house rats. Little or no difficulty was encountered with the mass air flow rack-suspended cage system during the 4 years it was used for the study of trace elements.

78 FR 28152 - Airworthiness Directives; Airbus Airplanes

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-14

... series airplanes. The existing AD currently requires repetitive inspections of the 80VU rack lower lateral fittings for damage; repetitive inspections of the 80VU rack lower central support for cracking... fittings of the 80VU rack. This proposed AD would reduce the inspection compliance time, add an inspection...

40 CFR 65.80 - Applicability.

Code of Federal Regulations, 2010 CFR

2010-07-01

... FEDERAL AIR RULE Transfer Racks § 65.80 Applicability. (a) The provisions of this subpart and of subpart A of this part apply to control of regulated material emissions from transfer racks where a referencing... is made that causes a transfer rack to fall outside the criteria in the referencing subpart that...

1. EAST SIDE OF OVERHEAD BOMB TRANSPORT RACK, WITH BUILDING ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. EAST SIDE OF OVERHEAD BOMB TRANSPORT RACK, WITH BUILDING 343 AT LEFT AND BUILDING 328 AT RIGHT. VIEW TO WEST. - Rocky Mountain Arsenal, Overhead Bomb Transport Rack, 1580 feet South of December Seventh Avenue; 860 feet West of D Street, Commerce City, Adams County, CO

26. A typical outer rod room, or rack room, showing ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

26. A typical outer rod room, or rack room, showing the racks for the nine horizontal control rods (HCRs) that would be inserted or withdrawn from the pile to control the rate of reaction. In this case, it is the 105-F Reactor in February 1945. The view is looking away from the pile, which is out of the picture on the left. Several of the cooling water hose reels for the rods can be seen at the end of the racks near the wall. D-8323 - B Reactor, Richland, Benton County, WA

MDCA (Multi-user Drop Combustion Apparatus) operations

NASA Image and Video Library

2009-05-12

ISS019-E-015912 (12 May 2009) --- Japan Aerospace Exploration Agency (JAXA) astronaut Koichi Wakata, Expedition 19/20 flight engineer, works on the Combustion Integrated Rack (CIR) Multi-user Drop Combustion Apparatus (MDCA) in the Destiny laboratory of the International Space Station. Wakata removed and replaced one fuel reservoir, which required temporary opening the front end cap and removing the fuel supply bypass Quick Disconnect (QD).

MDCA (Multi-user Drop Combustion Apparatus) operations

NASA Image and Video Library

2009-05-12

ISS019-E-015906 (12 May 2009) --- Japan Aerospace Exploration Agency (JAXA) astronaut Koichi Wakata, Expedition 19/20 flight engineer, works on the Combustion Integrated Rack (CIR) Multi-user Drop Combustion Apparatus (MDCA) in the Destiny laboratory of the International Space Station. Wakata removed and replaced one fuel reservoir, which required temporary opening the front end cap and removing the fuel supply bypass Quick Disconnect (QD).

MDCA (Multi-user Drop Combustion Apparatus) operations

NASA Image and Video Library

2009-05-12

ISS019-E-015910(12 May 2009) --- Japan Aerospace Exploration Agency (JAXA) astronaut Koichi Wakata, Expedition 19/20 flight engineer, works on the Combustion Integrated Rack (CIR) Multi-user Drop Combustion Apparatus (MDCA) in the Destiny laboratory of the International Space Station. Wakata removed and replaced one fuel reservoir, which required temporary opening the front end cap and removing the fuel supply bypass Quick Disconnect (QD).

Integration and use of Microgravity Research Facility: Lessons learned by the crystals by vapor transport experiment and Space Experiments Facility programs

NASA Technical Reports Server (NTRS)

Heizer, Barbara L.

1992-01-01

The Crystals by Vapor Transport Experiment (CVTE) and Space Experiments Facility (SEF) are materials processing facilities designed and built for use on the Space Shuttle mid deck. The CVTE was built as a commercial facility owned by the Boeing Company. The SEF was built under contract to the UAH Center for Commercial Development of Space (CCDS). Both facilities include up to three furnaces capable of reaching 850 C minimum, stand-alone electronics and software, and independent cooling control. In addition, the CVTE includes a dedicated stowage locker for cameras, a laptop computer, and other ancillary equipment. Both systems are designed to fly in a Middeck Accommodations Rack (MAR), though the SEF is currently being integrated into a Spacehab rack. The CVTE hardware includes two transparent furnaces capable of achieving temperatures in the 850 to 870 C range. The transparent feature allows scientists/astronauts to directly observe and affect crystal growth both on the ground and in space. Cameras mounted to the rack provide photodocumentation of the crystal growth. The basic design of the furnace allows for modification to accommodate techniques other than vapor crystal growth. Early in the CVTE program, the decision was made to assign a principal scientist to develop the experiment plan, affect the hardware/software design, run the ground and flight research effort, and interface with the scientific community. The principal scientist is responsible to the program manager and is a critical member of the engineering development team. As a result of this decision, the hardware/experiment requirements were established in such a way as to balance the engineering and science demands on the equipment. Program schedules for hardware development, experiment definition and material selection, flight operations development and crew training, both ground support and astronauts, were all planned and carried out with the understanding that the success of the program science was as important as the hardware functionality. How the CVTE payload was designed and what it is capable of, the philosophy of including the scientists in design and operations decisions, and the lessons learned during the integration process are descussed.

Using 3D infrared imaging to calibrate and refine computational fluid dynamic modeling for large computer and data centers

NASA Astrophysics Data System (ADS)

Stockton, Gregory R.

2011-05-01

Over the last 10 years, very large government, military, and commercial computer and data center operators have spent millions of dollars trying to optimally cool data centers as each rack has begun to consume as much as 10 times more power than just a few years ago. In fact, the maximum amount of data computation in a computer center is becoming limited by the amount of available power, space and cooling capacity at some data centers. Tens of millions of dollars and megawatts of power are being annually spent to keep data centers cool. The cooling and air flows dynamically change away from any predicted 3-D computational fluid dynamic modeling during construction and as time goes by, and the efficiency and effectiveness of the actual cooling rapidly departs even farther from predicted models. By using 3-D infrared (IR) thermal mapping and other techniques to calibrate and refine the computational fluid dynamic modeling and make appropriate corrections and repairs, the required power for data centers can be dramatically reduced which reduces costs and also improves reliability.

RACK1 upregulation induces neuroprotection by activating the IRE1-XBP1 signaling pathway following traumatic brain injury in rats.

PubMed

Ni, Haibo; Rui, Qin; Xu, Yitian; Zhu, Jun; Gao, Fan; Dang, Baoqi; Li, Di; Gao, Rong; Chen, Gang

2018-06-01

Receptor for activated protein kinase C 1 (RACK1) is a multifaceted scaffolding protein known to be involved in the regulation of signaling events required for neuronal protection. In the present study, we investigated the role of RACK1 in secondary brain injury in a rat traumatic brain injury (TBI) model. A weight-drop TBI model was established in Sprague Dawley rats, and RACK1 in vivo knockdown and overexpression were performed 24 h before TBI insult. The IRE1 inhibitor 3,5-dibromosalicylaldehyde (DBSA) was administered by intracerebroventricular injection 1 h after TBI insult. Real-time PCR, Western blotting, immunofluorescence, neuronal apoptosis, brain water content, and neurological scores were evaluated. Our results revealed that TBI induced increased expression of endogenous RACK1, phosphorylated inositol-requiring enzyme 1 (p-IRE1), X-box binding protein-1 (XBP1) and glucose-regulated protein 78 (GRP78) in neurons. RACK1 overexpression significantly ameliorated neuronal apoptosis, blood-brain barrier disruption, brain edema and neurological deficits at 48 h after TBI, which was concomitant with upregulation of p-IRE1, XBP1 and GRP78 expression, while its knockdown induced the opposite effects. Furthermore, DBSA administration reversed the protective effects of RACK1 overexpression against brain injury and decreased the expression of p-IRE1, XBP1 and GRP78. In summary, the upregulation of RACK1 following brain contusion exerted neuroprotective effects against secondary brain injury, which were probably mediated by activation of the IRE1-XBP1 pathway. Copyright © 2018. Published by Elsevier Inc.

77 FR 21734 - Certain Kitchen Appliance Shelving and Racks From the People's Republic of China: Final Results...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-11

... DEPARTMENT OF COMMERCE International Trade Administration [A-570-941] Certain Kitchen Appliance... duty order on certain kitchen appliance shelving and racks from the People's Republic of China (``PRC... Certain Kitchen Appliance Shelving and Racks From the People's Republic of China: Preliminary Results of...

NanoRacks CubeSat Deployment

NASA Image and Video Library

2014-02-13

ISS038-E-046586 (13 Feb. 2014) --- A set of NanoRacks CubeSats is photographed by an Expedition 38 crew member after the deployment by the NanoRacks Launcher attached to the end of the Japanese robotic arm. The CubeSats program contains a variety of experiments such as Earth observations and advanced electronics testing.

NanoRacks CubeSat Deployment

NASA Image and Video Library

2014-02-13

ISS038-E-046579 (13 Feb. 2014) --- A set of NanoRacks CubeSats is photographed by an Expedition 38 crew member after the deployment by the NanoRacks Launcher attached to the end of the Japanese robotic arm. The CubeSats program contains a variety of experiments such as Earth observations and advanced electronics testing.

40 CFR 65.7 - Monitoring, recordkeeping, and reporting waivers and alternatives, and alternative work practice...

Code of Federal Regulations, 2012 CFR

2012-07-01

... monitoring or recordkeeping provisions of this part. For process vents and transfer racks, except low-throughput transfer racks, the provisions in paragraph (c) of this section shall govern the review and... low throughput transfer racks, owners and operators shall comply with the requirements of § 65.145(b...

40 CFR 65.7 - Monitoring, recordkeeping, and reporting waivers and alternatives, and alternative work practice...

Code of Federal Regulations, 2011 CFR

2011-07-01

... monitoring or recordkeeping provisions of this part. For process vents and transfer racks, except low-throughput transfer racks, the provisions in paragraph (c) of this section shall govern the review and... low throughput transfer racks, owners and operators shall comply with the requirements of § 65.145(b...

40 CFR 65.7 - Monitoring, recordkeeping, and reporting waivers and alternatives, and alternative work practice...

Code of Federal Regulations, 2013 CFR

2013-07-01

... monitoring or recordkeeping provisions of this part. For process vents and transfer racks, except low-throughput transfer racks, the provisions in paragraph (c) of this section shall govern the review and... low throughput transfer racks, owners and operators shall comply with the requirements of § 65.145(b...

40 CFR 65.7 - Monitoring, recordkeeping, and reporting waivers and alternatives, and alternative work practice...

Code of Federal Regulations, 2014 CFR

2014-07-01

... monitoring or recordkeeping provisions of this part. For process vents and transfer racks, except low-throughput transfer racks, the provisions in paragraph (c) of this section shall govern the review and... low throughput transfer racks, owners and operators shall comply with the requirements of § 65.145(b...

40 CFR 65.7 - Monitoring, recordkeeping, and reporting waivers and alternatives, and alternative work practice...

Code of Federal Regulations, 2010 CFR

2010-07-01

... monitoring or recordkeeping provisions of this part. For process vents and transfer racks, except low-throughput transfer racks, the provisions in paragraph (c) of this section shall govern the review and... low throughput transfer racks, owners and operators shall comply with the requirements of § 65.145(b...

40 CFR 65.145 - Nonflare control devices used to control emissions from storage vessels or low-throughput...

Code of Federal Regulations, 2010 CFR

2010-07-01

... control emissions from storage vessels or low-throughput transfer racks. 65.145 Section 65.145 Protection... racks. (a) Nonflare control device equipment and operating requirements. The owner or operator shall...-throughput transfer rack, so that the monitored parameters defined as required in paragraph (c) of this...

40 CFR 63.985 - Nonflare control devices used to control emissions from storage vessels and low throughput...

Code of Federal Regulations, 2010 CFR

2010-07-01

... control emissions from storage vessels and low throughput transfer racks. 63.985 Section 63.985 Protection... transfer racks. (a) Nonflare control device equipment and operating requirements. The owner or operator... subpart for storage vessels and transfer racks, documentation that those conditions exist is sufficient to...

77 FR 27029 - Certain Kitchen Shelving and Racks From the People's Republic of China: Extension of Time Limit...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-08

... DEPARTMENT OF COMMERCE International Trade Administration [C-570-942] Certain Kitchen Shelving and Racks From the People's Republic of China: Extension of Time Limit for Preliminary Results of... certain kitchen appliance shelving and racks from the People's Republic of China, covering the review...

40 CFR 63.2338 - What parts of my plant does this subpart cover?

Code of Federal Regulations, 2010 CFR

2010-07-01

... transfer racks at which organic liquids are loaded into or unloaded out of transport vehicles and/or...) Storage tanks storing organic liquids; (ii) Transfer racks loading or unloading organic liquids; (iii... and a transfer rack subject to this subpart; and (v) Pipelines that transfer organic liquids directly...

40 CFR 65.84 - Operating requirements.

Code of Federal Regulations, 2010 CFR

2010-07-01

...) CONSOLIDATED FEDERAL AIR RULE Transfer Racks § 65.84 Operating requirements. (a) Closed vent systems or process piping. An owner or operator of a transfer rack shall operate it in such a manner that emissions are... per square inch). (d) Pressure relief device. The owner or operator of a transfer rack subject to the...

The Interplay Between Hardware and Control System Design in the Development of the Active Rack Isolation System

NASA Technical Reports Server (NTRS)

Fialho, Ian J.; Thampi, Sreekumar

2000-01-01

A primary mission of the International Space Station (ISS) is to provide a premier microgravity laboratory environment for conducting acceleration sensitive scientific research. In order to accomplish this goal, vibroacoustic disturbances caused by station activities that occur during the microgravity mode of operation, must be controlled. In addition to source isolation and other passive isolation methods, the ISS uses active isolation at the receiver, through the use of an Active Rack Isolation System (ARIS), as part of its overall vibration isolation strategy. A schematic diagram of a typical ARIS payload rack is shown. The ARIS isolation control system senses rack acceleration via three triaxial accelerometer heads and uses eight pushrod actuators to perform active vibration attenuation. Position sensors housed in the actuator assembly are used to sense the relative position between the rack and the station. Electrical power, data and other essential resources are routed through a set of umbilicals that interface with a passthrough panel at the bottom of the rack. A representative umbilical set is shown.

RACK1 and the microRNA pathway: is it déjà-vu all over again?

PubMed

Speth, Corinna; Laubinger, Sascha

2014-01-01

MicroRNAs (miRNAs) control many aspects of development and adaption in plants and in animals by post-transcriptional control of mRNA stability and translatability. Over the last years numerous proteins have been identified in the miRNA pathway. The versatile scaffold protein RACK1 has been associated with efficient miRNA production and function in plants and metazoans. Here, we briefly summarize the differences of RACK1 function in the plant and animal miRNA pathways and discuss putative mechanisms and functional roles of RACK1 in miRNA biogenesis and action.

System for handling and storing radioactive waste

DOEpatents

Anderson, J.K.; Lindemann, P.E.

1982-07-19

A system and method are claimed for handling and storing spent reactor fuel and other solid radioactive waste, including canisters to contain the elements of solid waste, storage racks to hold a plurality of such canisters, storage bays to store these racks in isolation by means of shielded doors in the bays. This system also includes means for remotely positioning the racks in the bays and an access tunnel within which the remotely operated means is located to position a rack in a selected bay. The modular type of these bays will facilitate the construction of additional bays and access tunnel extension.

Fail-safe storage rack for irradiated fuel rod assemblies

DOEpatents

Lewis, D.R.

1993-03-23

A fail-safe storage rack is provided for interim storage of spent but radioactive nuclear fuel rod assemblies. The rack consists of a checkerboard array of substantially square, elongate receiving tubes fully enclosed by a double walled container, the outer wall of which is imperforate for liquid containment and the inner wall of which is provided with perforations for admitting moderator liquid flow to the elongate receiving tubes, the liquid serving to take up waste heat from the stored nuclear assemblies and dissipate same to the ambient liquid reservoir. A perforated cover sealing the rack facilitates cooling liquid entry and dissipation.

System for handling and storing radioactive waste

DOEpatents

Anderson, John K.; Lindemann, Paul E.

1984-01-01

A system and method for handling and storing spent reactor fuel and other solid radioactive waste, including canisters to contain the elements of solid waste, storage racks to hold a plurality of such canisters, storage bays to store these racks in isolation by means of shielded doors in the bays. This system also includes means for remotely positioning the racks in the bays and an access tunnel within which the remotely operated means is located to position a rack in a selected bay. The modular type of these bays will facilitate the construction of additional bays and access tunnel extension.

Design Features and Capabilities of the First Materials Science Research Rack

NASA Technical Reports Server (NTRS)

Pettigrew, P. J.; Lehoczky, S. L.; Cobb, S. D.; Holloway, T.; Kitchens, L.

2003-01-01

The First Materials Science Research Rack (MSRR-1) aboard the International Space Station (ISS) will offer many unique capabilities and design features to facilitate a wide range of materials science investigations. The initial configuration of MSRR-1 will accommodate two independent Experiment Modules (EMS) and provide the capability for simultaneous on-orbit processing. The facility will provide the common subsystems and interfaces required for the operation of experiment hardware and accommodate telescience capabilities. MSRR1 will utilize an International Standard Payload Rack (ISPR) equipped with an Active Rack Isolation System (ARIS) for vibration isolation of the facility.

Fail-safe storage rack for irradiated fuel rod assemblies

DOEpatents

Lewis, Donald R.

1993-01-01

A fail-safe storage rack is provided for interim storage of spent but radioactive nuclear fuel rod assemblies. The rack consists of a checkerboard array of substantially square, elongate receiving tubes fully enclosed by a double walled container, the outer wall of which is imperforate for liquid containment and the inner wall of which is provided with perforations for admitting moderator liquid flow to the elongate receiving tubes, the liquid serving to take up waste heat from the stored nuclear assemblies and dissipate same to the ambient liquid reservoir. A perforated cover sealing the rack facilitates cooling liquid entry and dissipation.

Survey view of EXPRESS Rack 4 in the JPM during Expedition 22

NASA Image and Video Library

2009-12-30

iss022e015852 (12/30/2009) --- The image shows a front view of EXpedite the PRocessing of Experiments to Space Station EXPRESS Rack 4 (Rack 4,JPM/1F5) in the Japanese Experiment Module (JEM) Japanese Pressurized Module (JPM). Equipment visible in the EXPRESS Rack includes the Biotechnology Specimen Temperature Controller (BSTC) and the Gas Supply Module (GSM) support hardware for the CBOSS (Cellular Biotechnology Operations Support Systems) investigations, and the Device for the Study of Critical Liquids and Crystallization (DECLIC). Also visible is the Space Acceleration Measurement System (SAMS) II.

Approximating Fluid Flow from Ambient to Very Low Pressures: Modeling ISS Experiments that Vent to Vacuum

NASA Technical Reports Server (NTRS)

Minor, Robert

2002-01-01

Two ISS (International Space Station) experiment payloads will vent a volume of gas overboard via either the ISS Vacuum Exhaust System or the Vacuum Resource System. A system of ducts, valves and sensors, under design, will connect the experiments to the ISS systems. The following tasks are required: Create an analysis tool that will verify the rack vacuum system design with respect to design requirements, more specifically approximate pressure at given locations within the vacuum systems; Determine the vent duration required to achieve desired pressure within the experiment modules; Update the analysis as systems and operations definitions mature.

40 CFR 63.2342 - When do I have to comply with this subpart?

Code of Federal Regulations, 2014 CFR

2014-07-01

... operator must comply with the transfer rack requirements specified in § 63.2346(b) immediately; that is, be... transfer rack requirements specified in § 63.2346(b) immediately; that is, be in compliance the first day... owner or operator believes that compliance with the transfer rack emission limits cannot be achieved...

40 CFR 63.2342 - When do I have to comply with this subpart?

Code of Federal Regulations, 2010 CFR

2010-07-01

... operator must comply with the transfer rack requirements specified in § 63.2346(b) immediately; that is, be... transfer rack requirements specified in § 63.2346(b) immediately; that is, be in compliance the first day... owner or operator believes that compliance with the transfer rack emission limits cannot be achieved...

40 CFR 63.2342 - When do I have to comply with this subpart?

Code of Federal Regulations, 2011 CFR

2011-07-01

... operator must comply with the transfer rack requirements specified in § 63.2346(b) immediately; that is, be... transfer rack requirements specified in § 63.2346(b) immediately; that is, be in compliance the first day... owner or operator believes that compliance with the transfer rack emission limits cannot be achieved...

Experiments to the Space Station (EXPRESS) Rack 4

NASA Image and Video Library

2002-07-04

iss005e06720 (7/4/2002) --- Front view of Express Rack 4 in the U.S. Laboratory / Destiny taken during Expedition Five. Visible in the rack are the following items: Single-Locker Thermal Enclosure System (STES) Muffler, Advanced Astroculture Growth Chamber (ADVASC-GC), Advanced Astroculture Support System (ADVASC-SS). And Space Acceleration and Measurement System (SAMS) II.

40 CFR 65.165 - Initial Compliance Status Reports.

Code of Federal Regulations, 2010 CFR

2010-07-01

... comply with § 65.144 by routing emissions from a storage vessel or transfer rack to a process or to a... stream is connected to a fuel gas system. (3) As specified in § 65.144(c), report that the transfer rack... storage vessel or low-throughput transfer rack to a nonflare control device or halogen reduction device...

40 CFR 63.2358 - By what date must I conduct performance tests and other initial compliance demonstrations?

Code of Federal Regulations, 2010 CFR

2010-07-01

... racks at existing affected sources complying with the emission limitations listed in Table 2 to this... storage tanks and transfer racks at reconstructed or new affected sources complying with the emission... section, you must comply within 180 days after April 25, 2011. (2) For transfer racks and equipment leak...

40 CFR Table 3 to Subpart Eeee of... - Operating Limits-High Throughput Transfer Racks

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 12 2010-07-01 2010-07-01 true Operating Limits-High Throughput Transfer Racks 3 Table 3 to Subpart EEEE of Part 63 Protection of Environment ENVIRONMENTAL PROTECTION... Throughput Transfer Racks As stated in § 63.2346(e), you must comply with the operating limits for existing...

40 CFR 63.2343 - What are my requirements for emission sources not requiring control?

Code of Federal Regulations, 2010 CFR

2010-07-01

... of less than 18.9 cubic meters (5,000 gallons) and for each transfer rack subject to this subpart that only unloads organic liquids (i.e., no organic liquids are loaded at any of the transfer racks), you must keep documentation that verifies that each storage tank and transfer rack identified in...

Float Package and the Data Rack aboard the DC-9

NASA Technical Reports Server (NTRS)

1996-01-01

Ted Brunzie and Peter Mason observe the float package and the data rack aboard the DC-9 reduced gravity aircraft. The float package contains a cryostat, a video camera, a pump and accelerometers. The data rack displays and record the video signal from the float package on tape and stores acceleration and temperature measurements on disk.

Surveillance of a Ventilated Rack System for Corynebacterium bovis by Sampling Exhaust-Air Manifolds

PubMed Central

Manuel, Christopher A; Pugazhenthi, Umarani; Leszczynski, Jori K

2016-01-01

Corynebacterium bovis causes an opportunistic infection of nude (Foxn1, nu/nu) mice, leading to nude mouse hyperkeratotic dermatitis (scaly skin disease). Enzootic in many nude mouse colonies, C. bovis spreads rapidly to naive nude mice, despite modern husbandry practices, and is very difficult to eradicate. To facilitate rapid detection in support of eradication efforts, we investigated a surveillance method based on quantitative real-time PCR (qPCR) evaluation of swabs collected from the horizontal exhaust manifold (HEM) of an IVC rack system. We first evaluated the efficacy of rack sanitation methods for removing C. bovis DNA from the HEM of racks housing endemic colonies of infected nude mice. Pressurized water used to flush the racks’ air exhaust system followed by a standard rack-washer cycle was ineffective in eliminating C. bovis DNA. Only after autoclaving did all sanitized racks test negative for C. bovis DNA. We then measured the effects of stage of infection (early or established), cage density, and cage location on the rack on time-to-detection at the HEM. Stage of infection significantly affected time-to-detection, independent of cage location. Early infections required 7.3 ± 1.2 d whereas established infections required 1 ± 0 d for detection of C. bovis at the HEM. Cage density influenced the quantity of C. bovis DNA detected but not time-to-detection. The location of the cage on the rack affected the time-to-detection only during early C. bovis infections. We suggest that qPCR swabs of HEM are useful during the routine surveillance of nude mouse colonies for C. bovis infection. PMID:26817981

An Integrated Approach to Indoor and Outdoor Localization

DTIC Science & Technology

2017-04-17

localization estimate, followed by particle filter based tracking. Initial localization is performed using WiFi and image observations. For tracking we...source. A two-step process is proposed that performs an initial localization es-timate, followed by particle filter based t racking. Initial...mapped, it is possible to use them for localization [20, 21, 22]. Haverinen et al. show that these fields could be used with a particle filter to

Rack Distribution Effects on MPLM Center of Mass

NASA Technical Reports Server (NTRS)

Tester, John T.

2005-01-01

This research was in support of exploring the need for more flexible "center of gravity (CG) specifications than those currently established by NASA for the Multi-Purpose Logistics Module (MPLM). The MPLM is the cargo carrier for International Space Station (ISS) missions. The MPLM provides locations for 16 standard racks, as shown in Figure 1; not all positions need to be filled in any given flight. The MPLM coordinate system (X(sub M), Y(sub M), Z(sub M)) is illustrated as well. For this project, the primary missions of interest were those which supply the ISS and remove excess materials on the return flights. These flights use a predominate number of "Resupply Stowage Racks" (RSR) and "Resupply Stowage Platforms" (RSP). In these two types of racks, various smaller items are stowed. Hence, these racks will exhibit a considerable range of mass values as well as a range as to where their individual CG are located.

Reload of an industrial cylindrical cobalt source rack

NASA Astrophysics Data System (ADS)

Gharbi, F.; Kadri, O.; Trabelsi, A.

2006-10-01

This work presents a Monte Carlo study of the cylindrical cobalt source rack geometry of the Tunisian gamma irradiation facility, using the GEANT code developed at CERN. The study investigates the question of the reload of the source rack. The studied configurations consist in housing four new cobalt pencils, two in the upper and two in the lower cylinder of the source rack. Global dose rate uniformity inside a "dummy" product for the case of routine and nonroutine irradiation, and as function of the product bulk density, was calculated for eight hypothetical configurations. The same calculation was also performed for both of the original and the ideal (but not practical) configurations. It was shown that hypothetical cases produced dose uniformity variations, according to product density, that were statistically no different than the original and the ideal configurations and that the reload procedure cannot improve the irradiation quality inside the facilities using cylindrical cobalt source racks.

Rack assembly for mounting solar modules

DOEpatents

Plaisted, Joshua Reed; West, Brian

2010-12-28

A rack assembly is provided for mounting solar modules over an underlying body. The rack assembly may include a plurality of rail structures that are arrangeable over the underlying body to form an overall perimeter for the rack assembly. One or more retention structures may be provided with the plurality of rail structures, where each retention structure is configured to support one or more solar modules at a given height above the underlying body. At least some of the plurality of rail structures are adapted to enable individual rail structures o be sealed over the underlying body so as to constrain air flow underneath the solar modules. Additionally, at least one of (i) one or more of the rail structures, or (ii) the one or more retention structures are adjustable so as to adapt the rack assembly to accommodate solar modules of varying forms or dimensions.

Rack assembly for mounting solar modules

DOEpatents

Plaisted, Joshua Reed; West, Brian

2012-09-04

A rack assembly is provided for mounting solar modules over an underlying body. The rack assembly may include a plurality of rail structures that are arrangeable over the underlying body to form an overall perimeter for the rack assembly. One or more retention structures may be provided with the plurality of rail structures, where each retention structure is configured to support one or more solar modules at a given height above the underlying body. At least some of the plurality of rail structures are adapted to enable individual rail structures to be sealed over the underlying body so as to constrain air flow underneath the solar modules. Additionally, at least one of (i) one or more of the rail structures, or (ii) the one or more retention structures are adjustable so as to adapt the rack assembly to accommodate solar modules of varying forms or dimensions.

Rack assembly for mounting solar modules

DOEpatents

Plaisted, Joshua Reed; West, Brian

2014-06-10

A rack assembly is provided for mounting solar modules over an underlying body. The rack assembly may include a plurality of rail structures that are arrangeable over the underlying body to form an overall perimeter for the rack assembly. One or more retention structures may be provided with the plurality of rail structures, where each retention structure is configured to support one or more solar modules at a given height above the underlying body. At least some of the plurality of rail structures are adapted to enable individual rail structures o be sealed over the underlying body so as to constrain air flow underneath the solar modules. Additionally, at least one of (i) one or more of the rail structures, or (ii) the one or more retention structures are adjustable so as to adapt the rack assembly to accommodate solar modules of varying forms or dimensions.

Ultra-high-throughput microarray generation and liquid dispensing using multiple disposable piezoelectric ejectors.

PubMed

Hsieh, Huangpin Ben; Fitch, John; White, Dave; Torres, Frank; Roy, Joy; Matusiak, Robert; Krivacic, Bob; Kowalski, Bob; Bruce, Richard; Elrod, Scott

2004-03-01

The authors have constructed an array of 12 piezoelectric ejectors for printing biological materials. A single-ejector footprint is 8 mm in diameter, standing 4 mm high with 2 reservoirs totaling 76 micro L. These ejectors have been tested by dispensing various fluids in several environmental conditions. Reliable drop ejection can be expected in both humidity-controlled and ambient environments over extended periods of time and in hot and cold room temperatures. In a prototype system, 12 ejectors are arranged in a rack, together with an X - Y stage, to allow printing any pattern desired. Printed arrays of features are created with a biological solution containing bovine serum albumin conjugated oligonucleotides, dye, and salty buffer. This ejector system is designed for the ultra-high-throughput generation of arrays on a variety of surfaces. These single or racked ejectors could be used as long-term storage vessels for materials such as small molecules, nucleic acids, proteins, or cell libraries, which would allow for efficient preprogrammed selection of individual clones and greatly reduce the chance of cross-contamination and loss due to transfer. A new generation of design ideas includes plastic injection molded ejectors that are inexpensive and disposable and handheld personal pipettes for liquid transfer in the nanoliter regime.

40 CFR 63.11088 - What requirements must I meet for gasoline loading racks if my facility is a bulk gasoline...

Code of Federal Regulations, 2014 CFR

2014-07-01

... gasoline loading racks if my facility is a bulk gasoline terminal, pipeline breakout station, or pipeline... CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants for Source Category: Gasoline... § 63.11088 What requirements must I meet for gasoline loading racks if my facility is a bulk gasoline...

40 CFR 63.11088 - What requirements must I meet for gasoline loading racks if my facility is a bulk gasoline...

Code of Federal Regulations, 2010 CFR

2010-07-01

... gasoline loading racks if my facility is a bulk gasoline terminal, pipeline breakout station, or pipeline... CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants for Source Category: Gasoline... § 63.11088 What requirements must I meet for gasoline loading racks if my facility is a bulk gasoline...

40 CFR 63.11088 - What requirements must I meet for gasoline loading racks if my facility is a bulk gasoline...

Code of Federal Regulations, 2013 CFR

2013-07-01

... gasoline loading racks if my facility is a bulk gasoline terminal, pipeline breakout station, or pipeline... CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants for Source Category: Gasoline... § 63.11088 What requirements must I meet for gasoline loading racks if my facility is a bulk gasoline...

40 CFR 63.11088 - What requirements must I meet for gasoline loading racks if my facility is a bulk gasoline...

Code of Federal Regulations, 2011 CFR

2011-07-01

... gasoline loading racks if my facility is a bulk gasoline terminal, pipeline breakout station, or pipeline... CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants for Source Category: Gasoline... § 63.11088 What requirements must I meet for gasoline loading racks if my facility is a bulk gasoline...

40 CFR 63.11088 - What requirements must I meet for gasoline loading racks if my facility is a bulk gasoline...

Code of Federal Regulations, 2012 CFR

2012-07-01

... gasoline loading racks if my facility is a bulk gasoline terminal, pipeline breakout station, or pipeline... CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants for Source Category: Gasoline... § 63.11088 What requirements must I meet for gasoline loading racks if my facility is a bulk gasoline...

Lessons Learned from the Crew Health Care System (CHeCS) Rack 1 Environmental Control and Life Support (ECLS) Design

NASA Technical Reports Server (NTRS)

Williams, David E.

2006-01-01

This paper will provide an overview of the International Space Station (ISS) Environmental Control and Life Support (ECLS) design of the Crew Health Care System (CHeCS) Rack 1 and it will document some of the lessons that have been learned to date for the ECLS equipment in this rack.

76 FR 15295 - Floor-Standing, Metal-Top Ironing Tables and Certain Parts Thereof From the People's Republic of...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-21

... rests, linen racks, and others. The subject ironing tables may be sold with or without a pad and/or... an included feature such as an iron rest or linen rack. The term ``complete'' ironing table means... without additional features, e.g., iron rest or linen rack. The term ``incomplete'' ironing table means...

40 CFR 63.130 - Transfer operations provisions-periodic recordkeeping and reporting.

Code of Federal Regulations, 2010 CFR

2010-07-01

... from the control device is used, each owner or operator of a Group 1 transfer rack subject to the... of a Group 1 transfer rack who uses a flare to comply with § 63.126(b)(2) of this subpart shall keep...)(2) of this subpart. (d) Each owner or operator of a transfer rack subject to the requirements of...

75 FR 46873 - Airworthiness Directives; Airbus Model A318-111 and A318-112 Airplanes and Model A319, A320, and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-04

... fittings of the 80VU rack, typically elongated holes, migrated bushes [bushings], and/or missing bolts have... with a high load factor or strong vibration could lead to failure of the rack structure and/or... rack contains computers for Flight Controls, Communication and Radio-navigation. These functions are...

75 FR 3201 - Floor-Standing, Metal-Top Ironing Tables and Certain Parts Thereof From the People's Republic of...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-20

... available with various features, including iron rests, linen racks, and others. The subject ironing tables... linen rack. The term ``complete'' ironing table means product sold as a ready-to-use ensemble consisting... linen rack. The term ``incomplete'' ironing table means product shipped or sold as a ``bare board''--i.e...

77 FR 55806 - Floor-Standing, Metal-Top Ironing Tables and Certain Parts Thereof From the People's Republic of...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-11

... rests, linen racks, and others. The subject ironing tables may be sold with or without a pad and/or... an included feature such as an iron rest or linen rack. The term ``complete'' ironing table means... without additional features, e.g., iron rest or linen rack. The term ``incomplete'' ironing table means...

75 FR 36629 - Floor-Standing, Metal-Top Ironing Tables and Certain Parts Thereof from the People's Republic of...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-28

... various features, including iron rests, linen racks, and others. The subject ironing tables may be sold... top or the attachment of an included feature such as an iron rest or linen rack. The term ``complete... and cover, with or without additional features, e.g., iron rest or linen rack. The term ``incomplete...

Effect of Channel Catfish Ictalurus Punctatus Egg Mass Loading Rate on Performance of the “See-Saw” Incubator

USDA-ARS?s Scientific Manuscript database

The “See-Saw” is a vertical-lift incubator that increases water circulation around and through channel catfish egg masses. Baskets in the incubator move up and down on racks in conventional hatchery troughs, raising the rack in one trough while lowering the rack in the adjacent trough. Egg masses ...

40 CFR Table 9 to Subpart Eeee of... - Continuous Compliance With Operating Limits-High Throughput Transfer Racks

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 12 2010-07-01 2010-07-01 true Continuous Compliance With Operating Limits-High Throughput Transfer Racks 9 Table 9 to Subpart EEEE of Part 63 Protection of Environment...—Continuous Compliance With Operating Limits—High Throughput Transfer Racks As stated in §§ 63.2378(a) and (b...

77 FR 14499 - Floor-Standing, Metal-Top Ironing Tables and Certain Parts Thereof From the People's Republic of...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-12

... various features, including iron rests, linen racks, and others. The subject ironing tables may be sold... top or the attachment of an included feature such as an iron rest or linen rack. The term ``complete... and cover, with or without additional features, e.g., iron rest or linen rack. The term ``incomplete...

76 FR 15297 - Floor-Standing, Metal-Top Ironing Tables and Certain Parts Thereof From the People's Republic of...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-21

... rests, linen racks, and others. The subject ironing tables may be sold with or without a pad and/or... an included feature such as an iron rest or linen rack. The term ``complete'' ironing table means... without additional features, e.g., iron rest or linen rack. The term ``incomplete'' ironing table means...

75 FR 28475 - Airworthiness Directives; Airbus Model A330-200 and -300 Series Airplanes, and Model A340-300...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-21

... unsafe condition as: In the door 2 area, the hat-racks are supplied with a basic wire harness which includes ``Oxygen Masks'' activation. In case of a monument installation, the respective non-used hat- rack... door 2 area, the hat-racks are supplied with a basic wire harness which includes ``Oxygen Masks...

95. VIEW OF SOUTHWEST CORNER OF LANDLINE INSTRUMENTATION ROOM (106), ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

95. VIEW OF SOUTHWEST CORNER OF LANDLINE INSTRUMENTATION ROOM (106), LSB (BLDG. 770). BATTERY RACK FOR BACKUP BOOSTER POWER ON LEFT; BATTERY RACK FOR BACKUP AEROSPACE GROUND EQUIPMENT (AGE) POWER ON RIGHT. BATTERY CHARGER IS RIGHT OF BATTERY RACKS. - Vandenberg Air Force Base, Space Launch Complex 3, Launch Pad 3 West, Napa & Alden Roads, Lompoc, Santa Barbara County, CA

Laboratory racks are installed in the MPLM Leonardo

NASA Technical Reports Server (NTRS)

2000-01-01

In the Space Station Processing Facility, another laboratory rack is placed on the arm of the Rack Insertion Unit to lift it to the workstand height of the Multi-Purpose Logistics Module Leonardo (not seen). The MPLM will transport laboratory racks filled with equipment, experiments and supplies to and from the International Space Station aboard the Space Shuttle. Leonardo will be launched for the first time March 1, 2001, on Shuttle mission STS-102. On that flight, Leonardo will be filled with equipment and supplies to outfit the U.S. laboratory module, being carried to the ISS on the Jan. 19, 2001, launch of STS-98.

Benchmarking criticality analysis of TRIGA fuel storage racks.

PubMed

Robinson, Matthew Loren; DeBey, Timothy M; Higginbotham, Jack F

2017-01-01

A criticality analysis was benchmarked to sub-criticality measurements of the hexagonal fuel storage racks at the United States Geological Survey TRIGA MARK I reactor in Denver. These racks, which hold up to 19 fuel elements each, are arranged at 0.61m (2 feet) spacings around the outer edge of the reactor. A 3-dimensional model was created of the racks using MCNP5, and the model was verified experimentally by comparison to measured subcritical multiplication data collected in an approach to critical loading of two of the racks. The validated model was then used to show that in the extreme condition where the entire circumference of the pool was lined with racks loaded with used fuel the storage array is subcritical with a k value of about 0.71; well below the regulatory limit of 0.8. A model was also constructed of the rectangular 2×10 fuel storage array used in many other TRIGA reactors to validate the technique against the original TRIGA licensing sub-critical analysis performed in 1966. The fuel used in this study was standard 20% enriched (LEU) aluminum or stainless steel clad TRIGA fuel. Copyright © 2016. Published by Elsevier Ltd.

Effect of large wood retention at check dams on sediment continuity

NASA Astrophysics Data System (ADS)

Schmocker, Lukas; Schalko, Isabella; Weitbrecht, Volker

2017-04-01

Large wood transport during flood events may seriously increase the damage potential due to accumulations at river infrastructures. The large wood is therefore mostly retained upstream of populated areas using retention structures that often combine a check dam with a debris rack. One disadvantages of this structures is, that the bed-load gets retained along with the wood. Especially if large wood blocks the rack early during a flood event, sediment continuity is completely interrupted. This may lead to severe bed erosion downstream of the check dam. So far, no common design to retain large wood but maintain sediment continuity is available. One attempt to separate the large wood from the bed-load was made with the large wood retention structure at River Sihl in Zürich, Switzerland. The retention of the large wood occurs in a bypass channel located along the main river. The bypass is located at an outer river bend, where a separation of bed-load and large wood results due to the secondary currents induced by the river curvature. Large wood floats towards the outer bend due to inertia and the secondary currents whereas bed-load remains at the inner bend. The bypass is separated by a side weir from the main river to ensure that the bed-load remains in the river during bed forming discharges and flood events. New model test are currently carried out at the Laboratory of Hydraulics, Hydrology, and Glaciology (VAW) of ETH Zurich, where sediment continuity should be achieved using an inclined rack. The rack is inclined in flow direction with a degree of 45° to 20°. First results show that the large wood deposits at the upper part of the rack whereas the lower part of the rack remains free for bed-load transport. Furthermore, the backwater rise for the inclined rack due to the accumulated wood is considerably reduced compared to a vertical rack, as a large part of the rack remains clear for the flow to pass. The findings of this studies help to understand the complex interaction between sediment and large wood at a check dam retention structure. Furthermore, new retention structures and rack designs are available, where sediment continuity can partially be maintained to reduce downstream bed erosion.

Quantification, Distribution, and Possible Source of Bacterial Biofilm in Mouse Automated Watering Systems

PubMed Central

Meier, Thomas R; Maute, Carrie J; Cadillac, Joan M; Lee, Ji Young; Righter, Daniel J; Hugunin, Kelly MS; Deininger, Rolf A; Dysko, Robert C

2008-01-01

The use of automated watering systems for providing drinking water to rodents has become commonplace in the research setting. Little is known regarding bacterial biofilm growth within the water piping attached to the racks (manifolds). The purposes of this project were to determine whether the mouse oral flora contributed to the aerobic bacterial component of the rack biofilm, quantify bacterial growth in rack manifolds over 6 mo, assess our rack sanitation practices, and quantify bacterial biofilm development within sections of the manifold. By using standard methods of bacterial identification, the aerobic oral flora of 8 strains and stocks of mice were determined on their arrival at our animal facility. Ten rack manifolds were sampled before, during, and after sanitation and monthly for 6 mo. Manifolds were evaluated for aerobic bacterial growth by culture on R2A and trypticase soy agar, in addition to bacterial ATP quantification by bioluminescence. In addition, 6 racks were sampled at 32 accessible sites for evaluation of biofilm distribution within the watering manifold. The identified aerobic bacteria in the oral flora were inconsistent with the bacteria from the manifold, suggesting that the mice do not contribute to the biofilm bacteria. Bacterial growth in manifolds increased while they were in service, with exponential growth of the biofilm from months 3 to 6 and a significant decrease after sanitization. Bacterial biofilm distribution was not significantly different across location quartiles of the rack manifold, but bacterial levels differed between the shelf pipe and connecting elbow pipes. PMID:18351724

Quantification, distribution, and possible source of bacterial biofilm in mouse automated watering systems.

PubMed

Meier, Thomas R; Maute, Carrie J; Cadillac, Joan M; Lee, Ji Young; Righter, Daniel J; Hugunin, Kelly M S; Deininger, Rolf A; Dysko, Robert C

2008-03-01

The use of automated watering systems for providing drinking water to rodents has become commonplace in the research setting. Little is known regarding bacterial biofilm growth within the water piping attached to the racks (manifolds). The purposes of this project were to determine whether the mouse oral flora contributed to the aerobic bacterial component of the rack biofilm, quantify bacterial growth in rack manifolds over 6 mo, assess our rack sanitation practices, and quantify bacterial biofilm development within sections of the manifold. By using standard methods of bacterial identification, the aerobic oral flora of 8 strains and stocks of mice were determined on their arrival at our animal facility. Ten rack manifolds were sampled before, during, and after sanitation and monthly for 6 mo. Manifolds were evaluated for aerobic bacterial growth by culture on R2A and trypticase soy agar, in addition to bacterial ATP quantification by bioluminescence. In addition, 6 racks were sampled at 32 accessible sites for evaluation of biofilm distribution within the watering manifold. The identified aerobic bacteria in the oral flora were inconsistent with the bacteria from the manifold, suggesting that the mice do not contribute to the biofilm bacteria. Bacterial growth in manifolds increased while they were in service, with exponential growth of the biofilm from months 3 to 6 and a significant decrease after sanitization. Bacterial biofilm distribution was not significantly different across location quartiles of the rack manifold, but bacterial levels differed between the shelf pipe and connecting elbow pipes.

NanoRacks CubeSat

NASA Image and Video Library

2014-02-14

ISS038-E-047232 (14 Feb. 2014) --- A set of NanoRacks CubeSats is photographed by an Expedition 38 crew member after the deployment by the NanoRacks Launcher attached to the end of the Japanese robotic arm. The CubeSats program contains a variety of experiments such as Earth observations and advanced electronics testing. International Space Station solar array panels provide the backdrop for the scene.

1400164

NASA Image and Video Library

2014-03-10

ELEASA WILSON, KRAIG TERSIGNI, JUSTIN CARTLEDGE MISSION OPERATIONS LABORATORY - LABORATORY TRAINING COMPLEX (LTC), BUILDING 4663, EXPRESS RACK TRAINING, EMERALD BRICK (POWER DISTRIBUTION FOR EXPRESS RACK LAPTOP).

Overview of the Microgravity Science Glovebox (MSG) Facility and the Research Performed in the MSG

NASA Technical Reports Server (NTRS)

Jordan, Lee

2016-01-01

The Microgravity Science Glovebox (MSG) is a rack facility aboard the International Space Station (ISS) designed for investigation handling. The MSG was built by the European Space Agency (ESA) which also provides sustaining engineering support for the facility. The MSG has been operating on the ISS since July 2002 and is currently located in the US Laboratory Module. The unique design of the facility allows it to accommodate science and technology investigations in a "workbench" type environment. The facility has an enclosed working volume that is held at a negative pressure with respect to the crew living area. This allows the facility to provide two levels of containment for small parts, particulates, fluids, and gases. This containment approach protects the crew from possible hazardous operations that take place inside the MSG work volume. Research investigations operating inside the MSG are provided a large 255 liter enclosed work space, 1000 watts of direct current power via a versatile supply interface (120, 28, plus or minus 12, and 5 volts direct current), 1000 watts of cooling capability, video and data recording and real time downlink, ground commanding capabilities, access to ISS Vacuum Exhaust and Vacuum Resource Systems, and gaseous nitrogen supply. These capabilities make the MSG one of the most utilized facilities on ISS. The MSG has been used for over 27,000 hours of scientific payload operations. MSG investigations involve research in cryogenic fluid management, fluid physics, spacecraft fire safety, materials science, combustion, plant growth, biological studies and life support technology. The MSG facility is operated by the Payloads Operations Integration Center at Marshall Space Flight Center. Payloads may also operate remotely from different telescience centers located in the United States and Europe. The Investigative Payload Integration Manager (IPIM) is the focal to assist organizations that have payloads operating in the MSG facility. NASA provides an MSG engineering unit for payload developers to verify that their hardware is operating properly before actual operation on the ISS. This poster will provide an overview of the MSG facility, a synopsis of the research that has already been accomplished in the MSG, and an overview of video and biological upgrades. The author would like to acknowledge Teledyne Brown Engineering and the entire MSG Team for their inputs into this poster.

Acoustic Noise Prediction of the Amine Swingbed ISS ExPRESS Rack Payload

NASA Technical Reports Server (NTRS)

Welsh, David; Smith, Holly; Wang, Shuo

2010-01-01

Acoustics plays a vital role in maintaining the health, safety, and comfort of crew members aboard the International Space Station (ISS). In order to maintain this livable and workable environment, acoustic requirements have been established to ensure that ISS hardware and payload developers account for the acoustic emissions of their equipment and develop acoustic mitigations as necessary. These requirements are verified by an acoustic emissions test of the integrated hardware. The Amine Swingbed ExPRESS (Expedite the PRocessing of ExperimentS to Space) rack payload creates a unique challenge to the developers in that the payload hardware is transported to the ISS in phases, making an acoustic emissions test on the integrated flight hardware impossible. In addition, the payload incorporates a high back pressure fan and a diaphragm vacuum pump, which are recognized as significant and complex noise sources. In order to accurately predict the acoustic emissions of the integrated payload, the individual acoustic noise sources and paths are first characterized. These characterizations are conducted though a series of acoustic emissions tests on the individual payload components. Secondly, the individual acoustic noise sources and paths are incorporated into a virtual model of the integrated hardware. The virtual model is constructed with the use of hybrid method utilizing the Finite Element Acoustic (FEA) and Statistical Energy Analysis (SEA) techniques, which predict the overall acoustic emissions. Finally, the acoustic model is validated though an acoustic characterization test performed on an acoustically similar mock-up of the flight unit. The results of the validated acoustic model are then used to assess the acoustic emissions of the flight unit and define further acoustic mitigation efforts.

Modular avionics packaging standardization

NASA Astrophysics Data System (ADS)

Austin, M.; McNichols, J. K.

The Modular Avionics Packaging (MAP) Program for packaging future military avionics systems with the objective of improving reliability, maintainability, and supportability, and reducing equipment life cycle costs is addressed. The basic MAP packaging concepts called the Standard Avionics Module, the Standard Enclosure, and the Integrated Rack are summarized, and the benefits of modular avionics packaging, including low risk design, technology independence with common functions, improved maintainability and life cycle costs are discussed. Progress made in MAP is briefly reviewed.

Laboratory racks are installed in the MPLM Leonardo

NASA Technical Reports Server (NTRS)

2000-01-01

In the Space Station Processing Facility, the Rack Insertion Unit lifts another laboratory rack to the Multi-Purpose Logistics Module Leonardo, in the background. The MPLM is the first of three such pressurized modules that will serve as the International Space Station's '''moving vans,''' carrying laboratory racks filled with equipment, experiments and supplies to and from the International Space Station aboard the Space Shuttle. Leonardo will be launched for the first time March 1, 2001, on Shuttle mission STS-102. On that flight, Leonardo will be filled with equipment and supplies to outfit the U.S. laboratory module, being carried to the ISS on the Jan. 19, 2001, launch of STS-98.

Nonlinear dynamics of a rack-pinion-rack device powered by the Casimir force.

PubMed

Miri, MirFaez; Nekouie, Vahid; Golestanian, Ramin

2010-01-01

Using the lateral Casimir force-a manifestation of the quantum fluctuations of the electromagnetic field between objects with corrugated surfaces-as the main force transduction mechanism, a nanomechanical device with rich dynamical behaviors is proposed. The device is made of two parallel racks that are moving in the same direction and a pinion in the middle that couples with both racks via the noncontact lateral Casimir force. The built-in frustration in the device causes it to be very sensitive and react dramatically to minute changes in the geometrical parameters and initial conditions of the system. The noncontact nature of the proposed device could help with the ubiquitous wear problem in nanoscale mechanical systems.

Spacelab payload accommodation handbook. Preliminary issue

NASA Technical Reports Server (NTRS)

1976-01-01

The main characteristics of the Spacelab system are described. Sufficient information on Spacelab capabilities is provided to enable individual experimenters or payload planning groups to determine how their payload equipment can be accomodated by Spacelab topics discussed include major spacelab/experiment interfaces; Spacelab payload support systems and requirements the experiments must comply with to allow experiment design; and development and integration up to a level where a group of individual experiments are integrated into a complete Spacelab payload using Spacelab racks/floors and pallet segments. Integration of a complete Spacelab payload with Spacelab subsystems, primary module structure etc., integration of Spacelab with the Orbiter and basic operational aspects are also covered in this preliminary edition of the handbook which reflects the current Spacelab baseline design and is for information only.

78 FR 33406 - Clean River Power MR-1, LLC, Clean River Power MR-2, LLC, Clean River Power MR-3, LLC, Clean...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-04

..., 52-foot-high, 80-foot-wide intake structure with trash racks containing 2-inch clear bar spacing; (2... following new facilities: (1) A 37-foot-long, 23-foot-high, 80-foot- wide intake structure with trash racks... new facilities: (1) A 37- foot-long, 52-foot-high, 88-foot-wide intake structure with trash racks...

15. Detail of 1946 chain rack alot for moving blocks ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

15. Detail of 1946 chain rack alot for moving blocks on floor of drydock in far SE corner of South Section. In 1994 theme chain rack alots and accompanying blocking mechanisms were no longer in use and were extremely deteriorated. For view of system as originally installed, see 1946 historic copy photograph WA-116-E-33. - Puget Sound Naval Shipyard, Drydock No. 3, Farragut Avenue, Bremerton, Kitsap County, WA

RACK1 regulates mesenchymal cell recruitment during sexual and asexual reproduction of budding tunicates.

PubMed

Tatzuke, Yuki; Sunanaga, Takeshi; Fujiwara, Shigeki; Kawamura, Kaz

2012-08-15

A homolog of receptor for activated protein kinase C1 (RACK1) was cloned from the budding tunicate Polyandrocarpa misakiensis. By RT-PCR and in situ hybridization analyses, PmRACK1 showed biphasic gene expression during asexual and sexual reproduction. In developing buds, the signal was exclusively observed in the multipotent atrial epithelium and undifferentiated mesenchymal cells that contributed to morphogenesis by the mesenchymal-epithelial transition (MET). In juvenile zooids, the signal was first observable in germline precursor cells that arose as mesenchymal cell aggregated in the ventral hemocoel. In mature zooids, the germinal epithelium in the ovary and the pharynx were the most heavily stained parts. GFP reporter assay indicated that the ovarian expression of PmRACK1 was constitutive from germline precursor cells to oocytes. To elucidate the in vivo function of PmRACK1, RNA interference was challenged. When growing buds were incubated with 5 nmol/mL siRNA, most mesenchymal cells remained round and appeared to have no interactions with the extracellular matrix (ECM), causing lower activity of MET without any apparent effects on cell proliferation. The resultant zooids became growth-deficient. The dwarf zooids did not form buds or mature gonads. Prior to RNAi, buds were treated with human BMP4 that could induce PmRACK1 expression, which resulted in MET activity. We conclude that in P. misakiensis, PmRACK1 plays roles in mesenchymal cell recruitment during formation of somatic and gonad tissues, which contributes to zooidal growth and sexual and asexual reproduction. Copyright © 2012 Elsevier Inc. All rights reserved.

First results from experiments performed with the ESA Anthrorack during the D-2 Spacelab mission.

PubMed

Kuipers, A

1996-06-01

In 1993 four astronauts performed physiological experiments on the payload "Anthrorack" during the second German Spacelab mission D-2. The Anthrorack set-up is a Spacelab double rack developed under the management of the European Space Agency. It consists of an ECHO machine, a respiratory monitoring system (gas analyzer with flow meter), a blood centrifuge, an ergometer, a finger blood pressure device, ECG, body impedance measurement device and a respiratory inductance plethysmograph. Experiment-specific equipment was used as well. Nineteen investigators performed experiments in the cardiovascular, pulmonary, fluid-renal and nutritional physiology area. Results on central venous pressure, ocular pressure, vascular resistance, cardiac output, tissue thickness and orthostatic intolerance are presented in the cardiovascular area. In the pulmonary area first results are mentioned on O2 transport perfusion and ventilation distribution and breathing pattern. From the fluid-renal experiments, data from diuresis, sodium excretion and hormonal determinations are given. Finally results from glucose metabolism and nitrogen turnover experiments are presented.

First results from experiments performed with the ESA Anthrorack during the D-2 spacelab mission

NASA Astrophysics Data System (ADS)

Kuipers, A.

1996-06-01

In 1993 four astronauts performed physiological experiments on the payload "Anthrorack" during the second German Spacelab mission D-2. The Anthrorack set-up is a Spacelab double rack developed under the management of the European Space Agency. It consists of an ECHO machine, a respiratory monitoring system (gas analyzer with flow meter), a blood centrifuge, an ergometer, a finger blood pressure device, ECG, body impedance measurement device and a respiratory inductance plethysmograph. Experiment-specific equipment was used as well. Nineteen investigators performed experiments in the cardiovascular, pulmonary, fluid-renal and nutritional physiology area. Results on central venous pressure, ocular pressure, vascular resistance, cardiac output, tissue thickness and orthostatic intolerance are presented in the cardiovascular area. In the pulmonary area first results are mentioned on O 2 transport perfusion and ventilation distribution and breathing pattern. From the fluid-renal experiments, data from diuresis, sodium excretion and hormonal determinations are given. Finally results from glucose metabolism and nitrogen turnover experiments are presented.

Fluids and Materials Science Studies Utilizing the Microgravity-vibration Isolation Mount (MIM)

NASA Technical Reports Server (NTRS)

Herring, Rodney; Tryggvason, Bjarni; Duval, Walter

1998-01-01

Canada's Microgravity Sciences Program (MSP) is the smallest program of the ISS partners and so can participate in only a few, highly focused projects in order to make a scientific and technological impact. One focused project involves determining the effect of accelerations (g-jitter) on scientific measurements in a microgravity environment utilizing the Microgravity-vibration Isolation Mount (MIM). Many experiments share the common characteristic of having a fluid stage in their process. The quality of the experimental measurements have been expected to be affected by g-jitters which has lead the ISS program to include specifications to limit the level of acceleration allowed on a subset of experimental racks. From finite element analysis (FEM), the ISS structure will not be able to meet the acceleration specifications. Therefore, isolation systems are necessary. Fluid science results and materials science results show significant sensitivity to g-jitter. The work done to date should be viewed only as a first look at the issue of g-jitter sensitivity. The work should continue with high priority such that the international science community and the ISS program can address the requirement and settle on an agreed to overall approach as soon as possible.

Feasibility analysis of large length-scale thermocapillary flow experiment for the International Space Station

NASA Astrophysics Data System (ADS)

Alberts, Samantha J.

The investigation of microgravity fluid dynamics emerged out of necessity with the advent of space exploration. In particular, capillary research took a leap forward in the 1960s with regards to liquid settling and interfacial dynamics. Due to inherent temperature variations in large spacecraft liquid systems, such as fuel tanks, forces develop on gas-liquid interfaces which induce thermocapillary flows. To date, thermocapillary flows have been studied in small, idealized research geometries usually under terrestrial conditions. The 1 to 3m lengths in current and future large tanks and hardware are designed based on hardware rather than research, which leaves spaceflight systems designers without the technological tools to effectively create safe and efficient designs. This thesis focused on the design and feasibility of a large length-scale thermocapillary flow experiment, which utilizes temperature variations to drive a flow. The design of a helical channel geometry ranging from 1 to 2.5m in length permits a large length-scale thermocapillary flow experiment to fit in a seemingly small International Space Station (ISS) facility such as the Fluids Integrated Rack (FIR). An initial investigation determined the proposed experiment produced measurable data while adhering to the FIR facility limitations. The computational portion of this thesis focused on the investigation of functional geometries of fuel tanks and depots using Surface Evolver. This work outlines the design of a large length-scale thermocapillary flow experiment for the ISS FIR. The results from this work improve the understanding thermocapillary flows and thus improve technological tools for predicting heat and mass transfer in large length-scale thermocapillary flows. Without the tools to understand the thermocapillary flows in these systems, engineers are forced to design larger, heavier vehicles to assure safety and mission success.

40 CFR 63.2396 - What compliance options do I have if part of my plant is subject to both this subpart and another...

Code of Federal Regulations, 2010 CFR

2010-07-01

... criteria for control in table 2 to this subpart. (b) Compliance with other regulations for transfer racks. After the compliance dates specified in § 63.2342, if you have a transfer rack that is subject to 40 CFR part 61, subpart BB, and that transfer rack is in OLD operation, you must meet all of the requirements...

115. VIEW OF SOUTHWEST CORNER OF LANDLINE INSTRUMENTATION ROOM (206), ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

115. VIEW OF SOUTHWEST CORNER OF LANDLINE INSTRUMENTATION ROOM (206), LSB (BLDG. 751). BATTERY RACK ON LEFT FOR BACKUP BOOSTER POWER; BATTERY RACK ON RIGHT FOR BACKUP AEROSPACE GROUND EQUIPMENT (AGE) POWER. RECTIFIER SUPPLYING PRIMARY POWER ON THE RIGHT SIDE OF THE PHOTO; BATTERY CHARGER BETWEEN RECTIFIER AND BATTERY RACKS. - Vandenberg Air Force Base, Space Launch Complex 3, Launch Pad 3 East, Napa & Alden Roads, Lompoc, Santa Barbara County, CA

Norm-Optimal ILC Applied to a High-Speed Rack Feeder

NASA Astrophysics Data System (ADS)

Schindele, Dominik; Aschemann, Harald; Ritzke, Jöran

2010-09-01

Rack feeders as automated conveying systems for high bay rackings are of high practical importance. To shorten the transport times by using trajectories with increased kinematic values accompanying control measures for a reduction of the excited structural vibrations are necessary. In this contribution, the model-based design of a norm-optimal iterative learning control structure is presented. The rack feeder is modelled as an elastic multibody system. For the mathematical description of the bending deflections a Ritz ansatz is introduced. The tracking control design is performed separately for both axes using decentralised state space representations. Both the achievable performance and the resulting tracking accuracy of the proposed control concept are shown by measurement results from the experimental set-up.

KSC-01pp0249

NASA Image and Video Library

2001-02-03

An overhead crane lowers the Multi-Purpose Logistics Module Donatello onto a workstand. In the SSPF, Donatello will undergo processing by the payload test team, including integrated electrical tests with other Station elements in the SSPF, leak tests, electrical and software compatibility tests with the Space Shuttle (using the Cargo Integrated Test equipment) and an Interface Verification Test once the module is installed in the Space Shuttle’s payload bay at the launch pad. The most significant mechanical task to be performed on Donatello in the SSPF is the installation and outfitting of the racks for carrying the various experiments and cargo. Donatello will be launched on mission STS-130, currently planned for September 2004

CIR MDCA replacement

NASA Image and Video Library

2015-05-13

ISS043E190395 (05/13/2015) --- NASA astronaut Terry Virts prepares the Multi-user Droplet Combustion Apparatus from inside the Combustion Integrated Rack for upcoming runs of the FLame Extinguishment Experiment, or FLEX-2. The FLEX-2 experiment studies how quickly fuel burns, the conditions required for soot to form, and how mixtures of fuels evaporate before burning. Understanding these processes could lead to the production of a safer spacecraft as well as increased fuel efficiency for engines using liquid fuel on Earth.

Opportunities for research on Space Station Freedom

NASA Technical Reports Server (NTRS)

Phillips, Robert W.

1992-01-01

NASA has allocated research accommodations on Freedom (equipment, utilities, etc.) to the program offices that sponsor space-based research and development as follows: Space Science and Applications (OSSA)--52 percent, Commercial Programs (OCP)--28 percent, Aeronautics and Space Technology (OAST)--12 percent, and Space Flight (OSF)--8 percent. Most of OSSA's allocation will be used for microgravity and life science experiments; although OSSA's space physics, astrophysics, earth science and applications, and solar system exploration divisions also will use some of this allocation. Other Federal agencies have expressed an interest in using Space Station Freedom. They include the National Institutes of Health (NIH), U.S. Geological Survey, National Science Foundation, National Oceanic and Atmospheric Administration, and U.S. Departments of Agriculture and Energy. Payload interfaces with space station lab support equipment must be simple, and experiment packages must be highly contained. Freedom's research facilities will feature International Standard Payload Racks (ISPR's), experiment racks that are about twice the size of a Spacelab rack. ESA's Columbus lab will feature 20 racks, the U.S. lab will have 12 racks, and the Japanese lab will have 10. Thus, Freedom will have a total of 42 racks versus 8 for Space lab. NASA is considering outfitting some rack space to accommodate small, self-contained payloads similar to the Get-Away-Special canisters and middeck-locker experiment packages flown on Space Shuttle missions. Crew time allotted to experiments on Freedom at permanently occupied capability will average 25 minutes per rack per day, compared to six hours per rack per day on Spacelab missions. Hence, telescience--the remote operation of space-based experiments by researchers on the ground--will play a very important role in space station research. Plans for supporting life sciences research on Freedom focus on the two basic goals of NASA 's space life sciences program: to ensure the health, safety, and productivity of humans in space and to acquire fundamental knowledge of biological processes. Space-based research has already shown that people and plants respond the same way to the microgravity environment: they lose structure. However, the mechanisms by which they respond are different, and researchers do not yet know much about these mechanisms. Life science research accommodations on Freedom will include facilities for experiments designed to address this and other questions, in fields such as gravitational biology, space physiology, and biomedical monitoring and countermeasures research.

27 CFR 24.266 - Inventory losses.

Code of Federal Regulations, 2014 CFR

2014-04-01

... losses due to spillage, leakage, soakage, evaporation, and other losses normally occurring from racking... spillage, leakage, soakage, evaporation, and other losses normally occurring from racking and filtering. In...

27 CFR 24.266 - Inventory losses.

Code of Federal Regulations, 2011 CFR

2011-04-01

... losses due to spillage, leakage, soakage, evaporation, and other losses normally occurring from racking... spillage, leakage, soakage, evaporation, and other losses normally occurring from racking and filtering. In...

27 CFR 24.266 - Inventory losses.

Code of Federal Regulations, 2013 CFR

2013-04-01

... losses due to spillage, leakage, soakage, evaporation, and other losses normally occurring from racking... spillage, leakage, soakage, evaporation, and other losses normally occurring from racking and filtering. In...

27 CFR 24.266 - Inventory losses.

Code of Federal Regulations, 2012 CFR

2012-04-01

... losses due to spillage, leakage, soakage, evaporation, and other losses normally occurring from racking... spillage, leakage, soakage, evaporation, and other losses normally occurring from racking and filtering. In...

Definition of a RACK1 Interaction Network in Drosophila melanogaster Using SWATH-MS.

PubMed

Kuhn, Lauriane; Majzoub, Karim; Einhorn, Evelyne; Chicher, Johana; Pompon, Julien; Imler, Jean-Luc; Hammann, Philippe; Meignin, Carine

2017-07-05

Receptor for Activated protein C kinase 1 (RACK1) is a scaffold protein that has been found in association with several signaling complexes, and with the 40S subunit of the ribosome. Using the model organism Drosophila melanogaster , we recently showed that RACK1 is required at the ribosome for internal ribosome entry site (IRES)-mediated translation of viruses. Here, we report a proteomic characterization of the interactome of RACK1 in Drosophila S2 cells. We carried out Label-Free quantitation using both Data-Dependent and Data-Independent Acquisition (DDA and DIA, respectively) and observed a significant advantage for the Sequential Window Acquisition of all THeoretical fragment-ion spectra (SWATH) method, both in terms of identification of interactants and quantification of low abundance proteins. These data represent the first SWATH spectral library available for Drosophila and will be a useful resource for the community. A total of 52 interacting proteins were identified, including several molecules involved in translation such as structural components of the ribosome, factors regulating translation initiation or elongation, and RNA binding proteins. Among these 52 proteins, 15 were identified as partners by the SWATH strategy only. Interestingly, these 15 proteins are significantly enriched for the functions translation and nucleic acid binding. This enrichment reflects the engagement of RACK1 at the ribosome and highlights the added value of SWATH analysis. A functional screen did not reveal any protein sharing the interesting properties of RACK1, which is required for IRES-dependent translation and not essential for cell viability. Intriguingly however, 10 of the RACK1 partners identified restrict replication of Cricket paralysis virus (CrPV), an IRES-containing virus. Copyright © 2017 Kuhn et al.

Effects of suspension of air-conditioning on airtight-type racks.

PubMed

Kanzaki, M; Fujieda, M; Furukawa, T

2001-10-01

Although isolation racks are superior to open-type racks in terms of securing breeding conditions for laboratory animals, the contingency-proofing capability of the former has yet to be determined. Therefore, from the view of risk management, we studied the environmental change in isolation racks by forcibly suspending ventilation and air-conditioning and confirming the maximal time length for complete recovery to the original condition after restarting their operations. The isolation racks were placed in a room that was equipped with an independent air-conditioning system. When the inside condition of the racks reached 22-24 degrees C and 59-64% of relative humidity, the air-conditioning and ventilation were forcibly suspended and the subsequent temperature, relative humidity, ammonium and CO2 concentrations in the racks were measured over time. We found that after suspending the air-conditioning and ventilation, it took 40-60 min for temperature, and about 10 min for relative humidity to exceed the maximum values (temperature and relative humidity) referred to in the Showa 58 Nenban Guideline Jikken Doubutsu Shisetsu no Kenchiku oyobi Setsubi (Guidelines of buildings and facilities for experimental animals in Japan; Year 1983 edition). After 17 hr 25 min of the suspension of air-conditioning and ventilation, two rats were found dead. Then, the air-conditioning and ventilation were restarted. It took about 2 hr for temperature, and 50 min for relative humidity to regain the guideline values. The ammonium concentration stayed within the guideline value with a maximum concentration of 2 ppm in the experimental period, whereas the CO2 concentration was found to exceed 9% at the time of animal death.

Walleye dermal sarcoma virus Orf B functions through receptor for activated C kinase (RACK1) and protein kinase C

DOE Office of Scientific and Technical Information (OSTI.GOV)

Daniels, Candelaria C.; Rovnak, Joel; Quackenbush, Sandra L.

2008-06-05

Walleye dermal sarcoma virus is a complex retrovirus that is associated with walleye dermal sarcomas that are seasonal in nature. Fall developing tumors contain low levels of spliced accessory gene transcripts A and B, suggesting a role for the encoded proteins, Orf A and Orf B, in oncogenesis. In explanted tumor cells the 35 kDa Orf B accessory protein is localized to the cell periphery in structures similar to focal adhesions and along actin stress fibers. Similar localization was observed in mammalian cells. The cellular protein, receptor for activated C kinase 1 (RACK1), bound Orf B in yeast two-hybrid assaysmore » and in cell culture. Sequence analysis of walleye RACK1 demonstrated high conservation to other known RACK1 sequences. RACK1 binds to activated protein kinase C (PKC). Orf B associates with PKC{alpha}, which is constitutively activated and localized at the membrane. Activated PKC promoted cell survival, proliferation, and increased cell viability in Orf B-expressing cells.« less

Receptor for Activated C-Kinase 1 (PfRACK1) is required for Plasmodium falciparum intra-erythrocytic proliferation.

PubMed

Blomqvist, Karin; DiPetrillo, Christen; Streva, Vincent A; Pine, Stewart; Dvorin, Jeffrey D

2017-01-01

Emerging resistance to current anti-malarials necessitates a more detailed understanding of the biological processes of Plasmodium falciparum proliferation, thus allowing identification of new drug targets. The well-conserved protein Receptor for Activated C-Kinase 1 (RACK1) was originally identified in mammalian cells as an anchoring protein for protein kinase C (PKC) and has since been shown to be important for cell migration, cytokinesis, transcription, epigenetics, and protein translation. The P. falciparum ortholog, PfRACK1, is expressed in blood stages of the parasite and is diffusely localized in the parasite cytoplasm. Using a destabilizing domain to allow inducible knockdown of the endogenous protein level, we evaluated the requirement for PfRACK1 during blood-stage replication. Following destabilization, the parasites demonstrate a nearly complete growth arrest at the trophozoite stage. The essential nature of PfRACK1 suggests that the protein itself or the pathways regulated by the protein are potential targets for novel anti-malarial therapeutics. Copyright © 2016 Elsevier B.V. All rights reserved.

Design and Strength check of Large Blow Molding Machine Rack

NASA Astrophysics Data System (ADS)

Fei-fei, GU; Zhi-song, ZHU; Xiao-zhao, YAN; Yi-min, ZHU

Design procedure of large blow moulding machine rack is discussed in the article. A strength checking method is presented. Finite element analysis is conducted in the design procedure by ANSYS software. The actual situation of the rack load bearing is fully considered. The necessary means to simplify the model are done. The dimensional linear element Beam 188 is analyzed. MESH200 is used to mesh. Therefore, it simplifies the analysis process and improves computational efficiency. The maximum deformation of rack is 8.037 mm: it is occurred in the position of accumulator head. The result states: it meets the national standard curvature which is not greater than 0.3% of the total channel length; it also meets strength requirement that the maximum stress was 54.112 MPa.

STS-55 German Payload Specialist Schlegel manipulates ROTEX controls in SL-D2

NASA Technical Reports Server (NTRS)

1993-01-01

STS-55 German Payload Specialist 2 Hans Schlegel, wearing goggles (eye glasses) and positioned in front of Spacelab Deutsche 2 (SL-D2) Rack 4 System Rack controls, operates Robotics Technology Experiment (ROTEX) arm. ROTEX is a robotic arm that operates within an enclosed workcell in Rack 6 (partially visible in the foreground) and uses teleoperation from both an onboard station located nearby in Rack 4 and from a station on the ground. The device uses teleprogramming and artificial intelligence to look at the design, verification and operation of advanced autonomous systems for use in future applications. Schlegel represents the German Aerospace Research Establishment (DLR). SL-D2, a German-managed payload, is aboard Columbia, Orbiter Vehicle (OV) 102, for this science research mission.

INTERIOR OF COLD STORAGE ROOM, SHOWING MOVABLE HANGING RACKS. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

INTERIOR OF COLD STORAGE ROOM, SHOWING MOVABLE HANGING RACKS. - Naval Air Station Barbers Point, Aircraft Storehouse, Between Midway & Card Streets at Enterprise Avenue intersection, Ewa, Honolulu County, HI

Wakata performs microscopic analysis of the NanoRacks Module-38 Petri Dishes

NASA Image and Video Library

2014-01-13

ISS038-E-029082 (12 Jan. 2014) --- Japan Aerospace Exploration Agency astronaut Koichi Wakata, Expedition 38 flight engineer, performs microscopic analysis of the NanoRacks Module-38 Petri Dishes, using Celestron Reflective Microscope, in the Kibo laboratory of the International Space Station. These Module-38 experiments are designed by students as part of a competition sponsored by the International Space School Educational Trust (ISSET). This experiment examines three-dimensional growth of slime mold in petri dishes utilizing the NanoRacks Microscopes Facility.

40 CFR 65.87 - Recordkeeping provisions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... (CONTINUED) CONSOLIDATED FEDERAL AIR RULE Transfer Racks § 65.87 Recordkeeping provisions. The owner or operator of a transfer rack shall record that either the verification of U.S. Department of Transportation...

Development of a Simulation Capability for the Space Station Active Rack Isolation System

NASA Technical Reports Server (NTRS)

Johnson, Terry L.; Tolson, Robert H.

1998-01-01

To realize quality microgravity science on the International Space Station, many microgravity facilities will utilize the Active Rack Isolation System (ARIS). Simulation capabilities for ARIS will be needed to predict the microgravity environment. This paper discusses the development of a simulation model for use in predicting the performance of the ARIS in attenuating disturbances with frequency content between 0.01 Hz and 10 Hz. The derivation of the model utilizes an energy-based approach. The complete simulation includes the dynamic model of the ISPR integrated with the model for the ARIS controller so that the entire closed-loop system is simulated. Preliminary performance predictions are made for the ARIS in attenuating both off-board disturbances as well as disturbances from hardware mounted onboard the microgravity facility. These predictions suggest that the ARIS does eliminate resonant behavior detrimental to microgravity experimentation. A limited comparison is made between the simulation predictions of ARIS attenuation of off-board disturbances and results from the ARIS flight test. These comparisons show promise, but further tuning of the simulation is needed.

International Space Station USOS Crew Quarters Development

NASA Technical Reports Server (NTRS)

Broyan, James Lee, Jr.; Borrego, Melissa Ann; Bahr, Juergen F.

2008-01-01

The International Space Station (ISS) United States Operational Segment (USOS) currently provides a Temporary Sleep Station (TeSS) as crew quarters for one crewmember in the Laboratory Module. The Russian Segment provides permanent crew quarters (Kayutas) for two crewmembers in the Service Module. The TeSS provides limited electrical, communication, and ventilation functionality. A new permanent rack sized USOS ISS Crew Quarters (CQ) is being developed. Up to four CQs can be installed into the Node 2 element to increase the ISS crewmember size to six. The new CQs will provide private crewmember space with enhanced acoustic noise mitigation, integrated radiation reduction material, controllable airflow, communication equipment, redundant electrical systems, and redundant caution and warning systems. The rack sized CQ is a system with multiple crewmember restraints, adjustable lighting, controllable ventilation, and interfaces that allow each crewmember to personalize their CQ workspace. Providing an acoustically quiet and visually isolated environment, while ensuring crewmember safety, is critical for obtaining crewmember rest and comfort to enable long term crewmember performance. The numerous human factor, engineering, and program considerations during the concept, design, and prototyping are outlined in the paper.

Research progress and accomplishments on International Space Station

NASA Technical Reports Server (NTRS)

Roe, Lesa B.; Uri, John J.

2003-01-01

The first research payloads reached the International Space Station (ISS) more than two years ago, with research operating continuously since March 2001. Seven research racks are currently on-orbit, with three more arriving soon to expand science capabilities. Through the first five expeditions, 60 unique NASA-managed investigations from 11 nations have been supported, many continuing into later missions. More than 90,000 experiment hours have been completed, and more than 1,000 hours of crew time have been dedicated to research, numbers that grow daily. The multidisciplinary program includes research in life sciences, physical sciences, biotechnology, Earth sciences, technology demonstrations as well as commercial endeavors and educational activities. The Payload Operations and Integration Center monitors the onboard activities around the clock, working with numerous Principal Investigators and Payload Developers at their remote sites. Future years will see expansion of the station with research modules provided by the European Space Agency and Japan, which will be outfitted with additional research racks. c2003 American Institute of Aeronautics and Astronautics. Published by Elsevier Science Ltd. All rights reserved.

Research progress and accomplishments on International Space Station.

PubMed

Roe, Lesa B; Uri, John J

2003-01-01

The first research payloads reached the International Space Station (ISS) more than two years ago, with research operating continuously since March 2001. Seven research racks are currently on-orbit, with three more arriving soon to expand science capabilities. Through the first five expeditions, 60 unique NASA-managed investigations from 11 nations have been supported, many continuing into later missions. More than 90,000 experiment hours have been completed, and more than 1,000 hours of crew time have been dedicated to research, numbers that grow daily. The multidisciplinary program includes research in life sciences, physical sciences, biotechnology, Earth sciences, technology demonstrations as well as commercial endeavors and educational activities. The Payload Operations and Integration Center monitors the onboard activities around the clock, working with numerous Principal Investigators and Payload Developers at their remote sites. Future years will see expansion of the station with research modules provided by the European Space Agency and Japan, which will be outfitted with additional research racks. c2003 American Institute of Aeronautics and Astronautics. Published by Elsevier Science Ltd. All rights reserved.

Antenna cab interior showing equipment rack and fiberglass antenna panels, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Antenna cab interior showing equipment rack and fiberglass antenna panels, looking west. - Western Union Telegraph Company, Jennerstown Relay, Laurel Summit Road off U.S. 30, Laughlintown, Westmoreland County, PA

Antenna cab interior showing equipment rack and fiberglass antenna panels, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Antenna cab interior showing equipment rack and fiberglass antenna panels, looking southeast. - Western Union Telegraph Company, Jennerstown Relay, Laurel Summit Road off U.S. 30, Laughlintown, Westmoreland County, PA

Programs for Testing an SSME-Monitoring System

NASA Technical Reports Server (NTRS)

Lang, Andre; Cecil, Jimmie; Heusinger, Ralph; Freestone, Kathleen; Blue, Lisa; Wilkerson, DeLisa; McMahon, Leigh Anne; Hall, Richard B.; Varnavas, Kosta; Smith, Keary;

Operation and maintenance cost data for residential photovoltaic modules/panels

NASA Technical Reports Server (NTRS)

Oster, J. R., Jr.; Zaremski, D. R., Jr.; Albert, E. M.; Hawkins, S. L.

1980-01-01

Costs associated with the operation and maintenance of residential photovoltaic modules and arrays are studied. Six basic topics related to operation and maintenance to photovoltaic arrays are investigated: maintenance; cleaning; panel replacement; gasket repair/replacement; wiring repair/replacement; and termination repair/replacement. The effects of the mounting types (rack mount, stand off mount, direct mount and integral mount) and the installation/replacement type (sequential, partial interruption and independent) are identified and described. Methods of reducing maintenance costs are suggested.

18. Detail view of central pivot pier, drive gear rack, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

18. Detail view of central pivot pier, drive gear rack, and stabilizing wheel, looking southwest - India Point Railroad Bridge, Spanning Seekonk River between Providence & East Providence, Providence, Providence County, RI

40 CFR 65.82 - Design requirements.

Code of Federal Regulations, 2010 CFR

2010-07-01

...) CONSOLIDATED FEDERAL AIR RULE Transfer Racks § 65.82 Design requirements. (a) The owner or operator shall equip each transfer rack with either one of the following equipment: (1) A closed vent system which routes...

4. DETAIL VIEW OF LIFTING GEAR ON MULE AND RACK ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. DETAIL VIEW OF LIFTING GEAR ON MULE AND RACK ATTACHMENT BOOKS, LOOKING EAST - Nine Mile Hydroelectric Development, Powerhouse, State Highway 291 along Spokane River, Nine Mile Falls, Spokane County, WA

International Space Station (ISS)

NASA Image and Video Library

2001-02-01

The Payload Operations Center (POC) is the science command post for the International Space Station (ISS). Located at NASA's Marshall Space Flight Center in Huntsville, Alabama, it is the focal point for American and international science activities aboard the ISS. The POC's unique capabilities allow science experts and researchers around the world to perform cutting-edge science in the unique microgravity environment of space. The POC is staffed around the clock by shifts of payload flight controllers. At any given time, 8 to 10 flight controllers are on consoles operating, plarning for, and controlling various systems and payloads. This photograph shows a Payload Rack Officer (PRO) at a work station. The PRO is linked by a computer to all payload racks aboard the ISS. The PRO monitors and configures the resources and environment for science experiments including EXPRESS Racks, multiple-payload racks designed for commercial payloads.

A "Kanes's Dynamics" Model for the Active Rack Isolation System

NASA Technical Reports Server (NTRS)

Hampton, R. David; Beech, Geoffrey

1999-01-01

Many microgravity space-science experiments require vibratory acceleration levels unachievable without active isolation. The Boeing Corporation's Active Rack Isolation System (ARIS) employs a novel combination of magnetic actuation and mechanical linkages, to address these isolation requirements on the International Space Station (ISS). ARIS provides isolation at the rack (international Standard Payload Rack, or ISPR) level. Effective model-based vibration isolation requires (1) an appropriate isolation device, (2) an adequate dynamic (i.e., mathematical) model of that isolator, and (3) a suitable, corresponding controller. ARIS provides the ISS response to the first requirement. This paper presents one response to the second, in a state-space framework intended to facilitate an optimal-controls approach to the third. The authors use "Kane's Dynamics" to develop an state-space, analytical (algebraic) set of linearized equations of motion for ARIS.

Materials Science Research Rack-1 (MSRR-1)

NASA Technical Reports Server (NTRS)

2001-01-01

This computer-generated image depicts the Materials Science Research Rack-1 (MSRR-1) being developed by NASA's Marshall Space Flight Center and the European Space Agency (ESA) for placement in the Destiny laboratory module aboard the International Space Station. The rack is part of the plarned Materials Science Research Facility (MSRF) and is expected to include two furnace module inserts, a Quench Module Insert (being developed by NASA's Marshall Space Flight Center) to study directional solidification in rapidly cooled alloys and a Diffusion Module Insert (being developed by the European Space Agency) to study crystal growth, and a transparent furnace (being developed by NASA's Space Product Development program). Multi-user equipment in the rack is being developed under the auspices of NASA's Office of Biological and Physical Research (OBPR) and ESA. Key elements are labeled in other images (0101754, 0101829, 0101830, and TBD).

Materials Science Research Rack-1 (MSRR-1)

NASA Technical Reports Server (NTRS)

2001-01-01

This computer-generated image depicts the Materials Science Research Rack-1 (MSRR-1) being developed by NASA's Marshall Space Flight Center and the European Space Agency (ESA) for placement in the Destiny laboratory module aboard the International Space Station. The rack is part of the plarned Materials Science Research Facility (MSRF) and is expected to include two furnace module inserts, a Quench Module Insert (being developed by NASA's Marshall Space Flight Center) to study directional solidification in rapidly cooled alloys and a Diffusion Module Insert (being developed by the European Space Agency) to study crystal growth, and a transparent furnace (being developed by NASA's Space Product Development program). Multi-user equipment in the rack is being developed under the auspices of NASA's Office of Biological and Physical Research (OBPR) and ESA. A larger image is available without labels (No. 0101755).

Materials Science Research Rack-1 (MSRR-1)

NASA Technical Reports Server (NTRS)

2001-01-01

This computer-generated image depicts the Materials Science Research Rack-1 (MSRR-1) being developed by NASA's Marshall Space Flight Center and the European Space Agency (ESA) for placement in the Destiny laboratory module aboard the International Space Station. The rack is part of the plarned Materials Science Research Facility (MSRF) and is expected to include two furnace module inserts, a Quench Module Insert (being developed by NASA's Marshall Space Flight Center) to study directional solidification in rapidly cooled alloys and a Diffusion Module Insert (being developed by the European Space Agency) to study crystal growth, and a transparent furnace (being developed by NASA's Space Product Development program). Multi-user equipment in the rack is being developed under the auspices of NASA's Office of Biological and Physical Research (OBPR) and ESA. Key elements are labeled in other images (0101754, 0101830, and TBD).

Materials Science Research Rack-1 (MSRR-1)

NASA Technical Reports Server (NTRS)

2001-01-01

This scale model depicts the Materials Science Research Rack-1 (MSRR-1) being developed by NASA's Marshall Space Flight Center and the European Space Agency (ESA) for placement in the Destiny laboratory module aboard the International Space Station. The rack is part of the plarned Materials Science Research Facility (MSRF) and is expected to include two furnace module inserts, a Quench Module Insert (being developed by NASA's Marshall Space Flight Center) to study directional solidification in rapidly cooled alloys and a Diffusion Module Insert (being developed by the European Space Agency) to study crystal growth, and a transparent furnace (being developed by NASA's Space Product Development program). Multi-user equipment in the rack is being developed under the auspices of NASA's Office of Biological and Physical Research (OBPR) and ESA. Key elements are labeled in other images (0101754, 0101829, 0101830, and TBD).

Materials Science Research Rack-1 (MSRR-1)

NASA Technical Reports Server (NTRS)

2001-01-01

This computer-generated image depicts the Materials Science Research Rack-1 (MSRR-1) being developed by NASA's Marshall Space Flight Center and the European Space Agency (ESA) for placement in the Destiny laboratory module aboard the International Space Station. The rack is part of the plarned Materials Science Research Facility (MSRF) and is expected to include two furnace module inserts, a Quench Module Insert (being developed by NASA's Marshall Space Flight Center) to study directional solidification in rapidly cooled alloys and a Diffusion Module Insert (being developed by the European Space Agency) to study crystal growth, and a transparent furnace (being developed by NASA's Space Product Development program). Multi-user equipment in the rack is being developed under the auspices of NASA's Office of Biological and Physical Research (OBPR) and ESA. Key elements are labeled in other images (0101754, 0101829, 0101830).

KSC-05PD-0372

NASA Technical Reports Server (NTRS)

2005-01-01

KENNEDY SPACE CENTER, FLA. In the Space Station Processing Facility, the Rack Insertion Device moves the Human Research Facility-2 (HRF-2) science rack toward the Multi-Purpose Logistics Module Raffaello (at left) for flight on Space Shuttle Discoverys Return to Flight mission, STS-114. The HRF-2 will deliver additional biomedical instrumentation and research capability to the International Space Station. HRF-1, installed on the U.S. Lab since May 2001, contains an ultrasound unit and gas analyzer. Both racks provide structural, power, thermal, command and data handling, and communication and tracking interfaces between the HRF biomedical instrumentation and the U.S. Laboratory, Destiny. NASA Kennedy Space Center and their prime contractor responsible for ISS element processing, The Boeing Company, prepared the rack for installation. The HRF Project is managed by NASA Johnson Space Center and implemented through contract with Lockheed Martin, Houston, Texas.

A "Kane's Dynamics" Model for the Active Rack Isolation System

NASA Technical Reports Server (NTRS)

Hampton, R. D.; Beech, G. S.; Rao, N. N. S.; Rupert, J. K.; Kim, Y. K.

2001-01-01

Many microgravity space science experiments require vibratory acceleration levels unachievable without active isolation. The Boeing Corporation's Active Rack Isolation System (ARIS) employs a novel combination of magnetic actuation and mechanical linkages to address these isolation requirements on the International Space Station (ISS). ARIS provides isolation at the rack (International Standard Payload Rack (ISPR)) level. Effective model-based vibration isolation requires: (1) an appropriate isolation device, (2) an adequate dynamic (i.e., mathematical) model of that isolator, and (3) a suitable, corresponding controller. ARIS provides the ISS response to the first requirement. This paper presents one response to the second, in a state space framework intended to facilitate an optimal-controls approach to the third. The authors use "Kane's Dynamics" to develop a state-space, analytical (algebraic) set of linearized equations of motion for ARIS.

'Swab racks are an old fashioned idea'.

PubMed

Mumford, M

1991-12-01

Mary Mumford, theatre sister at the Princes of Wales Hospital, Bridgend, was asked to speak in a short debate at an NATN branch meeting, supporting the motion that 'swab racks are an old fashioned idea'. Although she did not like swab racks she had not attempted thus far to do anything about them. In the event, she actually lost the debate--not in principle but because she could offer no effective alternative method of checking swabs. Having been given the incentive, a trial is now being conducted in her hospital similar to that described by Paul Wicker. This is the case presented by Mary Mumford supporting the following motion ... 'that swab racks are an old fashioned idea, which cause more potential problems due to exposure of blood than is proven to be safe in today's theatre environment'.

Evaluation of food storage racks available on the Polish market in the hygienic context

PubMed

Grzesińska, Wiesława; Tomaszewska, Marzena; Bilska, Beata; Trafiałek, Joanna; Dziadek, Michał

Providing safe food products to the consumer depends on the material and technology used and adherence to hygienic practices, throughout the production process. The degree of microbial contamination of a surface is an important indicator of equipment cleanliness and effectiveness of cleaning and disinfection. Used material, construction solutions and quality of the applied devices also have an effect on hygienic status. The objective of the present study was to evaluate the influence of the design and construction material of selected food storage racks, available on the Polish market, on their hygienic status. The study was based on determination of the capability of microbial growth on the surface of the racks and the effectiveness of their cleaning. Microbiological cleanliness on the surface of the racks was monitored by the contact plates which are able to estimate the total number of icroorganisms. Examination of effectiveness of cleaning was conducted by the use of ATP bioluminescence method. This experiment has proven a significant influence of adopted construction solutions on the hygienic status of the examined racks. Presence of antibacterial layer and a choice of the appropriate construction material characterized by a low surface roughness impedes the microbial growth and increases the effectiveness of cleaning. Design solutions have significant impact on the hygienic status of shelves. Selection of a suitable material for the construction of racks can greatly reduce the possibility of the development of microorganism, despite the low efficiency of the cleaning. The application of antimicrobial coatings inhibits microbial growth.

Furniture Rack Corrosion Coupon Surveillance - 2012 Update

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mickalonis, J. I.; Murphy, T. R.; Berry, C. J.

Under the L Basin corrosion surveillance program furniture rack coupons immersed for 14 years (FY2009 coupons) and 16 years (FY2011 coupons) were analyzed and the results trended with coupons exposed for shorter times. In addition, a section harvested from an actual furniture rack that was immersed for 14 years was analyzed for pitting in the weld and heat-affected-zone (HAZ) regions. The L Basin operations maintained very good water quality over the entire immersion period for these samples. These results for FY2009 and FY2011 coupons showed that the average pit depths for the 6061 and 6063 base metal are 1 andmore » 2 mils, respectively, while those for the weld and HAZ are 3 and 4 mils, respectively. The results for the weld and HAZ regions are similar to coupons removed during the period of FY2003 to FY2007. These similarities indicate that the pit development occurred quickly followed by slow kinetics of increase in pit depth. For the actual furniture rack sample average pits of 5 and 2 mils were measured for the HAZ and weld, respectively. These results demonstrate that pitting corrosion of the aluminum furniture racks used to support the spent fuel occurs in waters of good quality. The corrosion kinetics or pit depth growth rate is much less that 1 mil/year, and would not impact long-term use of this material system for fuel storage racks in L Basin if good water quality is maintained.« less

KSC01pp0018

NASA Image and Video Library

2001-01-03

KENNEDY SPACE CENTER, Fla. -- Bright morning sun shines on Space Shuttle Atlantis as it sits on Launch Pad 39A. In front of the wings, on either side of the orbiter are tail service masts, which support the fluid, gas and electrical requirements of the orbiter’s liquid oxygen and liquid hydrogen aft T-0 umbilicals. Atlantis will fly on mission STS-98, the seventh construction flight to the International Space Station, carrying the U.S. Laboratory, named Destiny. The lab has five system racks already installed inside the module. After delivery of electronics in the lab, electrically powered attitude control for Control Moment Gyroscopes will be activated. Atlantis is scheduled for launch no earlier than Jan. 19, 2001, with a crew of five

14. DETAILS OF GATE OPERATING MECHANISM, SHOWING RACK SECTION, CUT ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

14. DETAILS OF GATE OPERATING MECHANISM, SHOWING RACK SECTION, CUT TEETH, CAST TEETH, GATE PINION (1907) - Nine Mile Hydroelectric Development, Powerhouse, State Highway 291 along Spokane River, Nine Mile Falls, Spokane County, WA

EXPRESS Rack 4 during Expedition Five

NASA Image and Video Library

2002-07-02

iss005e06524 (7/2/2002) --- View of the Single-Locker Thermal Enclosure System (STES), located on the Expedite the Processing of Experiments to the Space Station (EXPRESS) Rack 4 in the Destiny / U.S. Laboratory.

HANDMADE WOODEN RACK FOR TOOL STORE, LOWER LEVEL OF HYDROELECTRIC ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

HANDMADE WOODEN RACK FOR TOOL STORE, LOWER LEVEL OF HYDROELECTRIC POWER HOUSE - St. Lucie Canal, Lock No. 1, Hydroelectric Power House, St. Lucie, Cross State Canal, Okeechobee Intracoastal Waterway, Stuart, Martin County, FL

29. VIEW OF 4TH FLOOR'S TELEPHONE RACKS WITH CABLE TRAYS ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

29. VIEW OF 4TH FLOOR'S TELEPHONE RACKS WITH CABLE TRAYS ABOVE. THESE ARE NEWER APPARATUS AND NOT ORIGINAL. - Pacific Telephone & Telegraph Company Building, 1519 Franklin Street, Oakland, Alameda County, CA