Sample records for focusing system including

  1. Phase-shifting point diffraction interferometer focus-aid enhanced mask

    DOEpatents

    Naulleau, Patrick

    2000-01-01

    A phase-shifting point diffraction interferometer system (PS/PDI) employing a PS/PDI mask that includes a PDI focus aid is provided. The PDI focus aid mask includes a large or secondary reference pinhole that is slightly displaced from the true or primary reference pinhole. The secondary pinhole provides a larger capture tolerance for interferometrically performing fine focus. With the focus-aid enhanced mask, conventional methods such as the knife-edge test can be used to perform an initial (or rough) focus and the secondary (large) pinhole is used to perform interferometric fine focus. Once the system is well focused, high accuracy interferometry can be performed using the primary (small) pinhole.

  2. Economic Evaluation Research in the Context of Child Welfare Policy: A Structured Literature Review and Recommendations

    PubMed Central

    Goldhaber-Fiebert, Jeremy D.; Snowden, Lonnie R.; Wulczyn, Fred; Landsverk, John; Horwitz, Sarah M.

    2011-01-01

    Objectives With over 1 million children served by the U.S. Child Welfare system at a cost of $20 billion annually, this study examines the economic evaluation literature on interventions to improve outcomes for children at risk for and currently involved with the system, identifies areas where additional research is needed, and discusses the use of decision-analytic modeling to advance Child Welfare policy and practice. Methods The review included 19 repositories of peer-reviewed and non-peer-reviewed “gray” literatures, including items in English published before November, 2009. Original research articles were included if they evaluated interventions based on costs and outcomes. Review articles were included to assess the relevance of these techniques over time and to highlight the increasing discussion of methods needed to undertake such research. Items were categorized by their focus on: interventions for the U.S. Child Welfare system; primary prevention of entry into the system; and use of models to make long-term projections of costs and outcomes. Results Searches identified 2,640 articles, with 49 ultimately included (19 reviews and 30 original research articles). Between 1988 and 2009, reviews consistently advocated economic evaluation and increasingly provided methodological guidance. 21 of the original research articles focused on Child Welfare, while 9 focused on child mental health. Of the 21 Child Welfare articles, 81% (17) focused on the U.S. system. 47% (8/17) focused exclusively on primary prevention, though 83% of the U.S. system, peer-reviewed articles focused exclusively on prevention (5/6). 9 of the 17 articles included empirical follow-up (mean sample size: 264 individuals; mean follow-up: 3.8 years). 10 of the 17 articles used modeling to project longer-term outcomes, but 80% of the articles using modeling were not peer-reviewed. Although 60% of modeling studies included interventions for children in the system, all peer-reviewed modeling articles focused on prevention. Conclusions Methodological guidance for economic evaluations in Child Welfare is increasingly available. Such analyses are feasible given the availability of nationally-representative data on children involved with Child Welfare and evidence-based interventions. Practice Implications Policy analyses considering the long-term costs and effects of interventions to improve Child Welfare outcomes are scarce, feasible, and urgently needed. PMID:21944552

  3. PREFACE: Focus section on superconducting power systems Focus section on superconducting power systems

    NASA Astrophysics Data System (ADS)

    Cardwell, D. A.; Amemiya, N.; Fair, R.

    2012-01-01

    This focus section of Superconductor Science and Technology looks at the properties, technology and applications of (RE)BCO and MgB2 based superconductors for power engineering systems. Both bulk and conductor forms of material are addressed, including elements of materials fabrication and processing, and the measurement of their applied properties for various levels of system application. The areas of research include ac losses in type II materials in power devices, cables and coated conductors, the development of high current dc cables and the application of superconductors in levitation devices, motors and fault current limiters. This focus section presents a broad cross-section of contemporary issues, that represent state-of-the-art for power applications of superconductors, and highlights the areas that require further development if commercial applications of these rapidly emerging materials are to be realised. It contains papers from some of the major groups in the field, including contributions from Europe, the USA and Japan, and describes devices that are relatively close to market.

  4. Autofocus system and autofocus method for focusing on a surface

    DOEpatents

    O'Neill, Mary Morabito

    2017-05-23

    An autofocus system includes an imaging device, a lens system and a focus control actuator that is configured to change a focus position of the imaging device in relation to a stage. The electronic control unit is configured to control the focus control actuator to a plurality of predetermined focus positions, and activate the imaging device to obtain an image at predetermined positions and then apply a spatial filter to the obtained images. This generates a filtered image for the obtained images. The control unit determines a focus score for the filtered images such that the focus score corresponds to a degree of focus in the obtained images. The control unit identifies a best focus position by comparing the focus score of the filtered images, and controls the focus control actuator to the best focus position corresponding to the highest focus score.

  5. Electrostatically focused addressable field emission array chips (AFEA's) for high-speed massively parallel maskless digital E-beam direct write lithography and scanning electron microscopy

    DOEpatents

    Thomas, Clarence E.; Baylor, Larry R.; Voelkl, Edgar; Simpson, Michael L.; Paulus, Michael J.; Lowndes, Douglas H.; Whealton, John H.; Whitson, John C.; Wilgen, John B.

    2002-12-24

    Systems and methods are described for addressable field emission array (AFEA) chips. A method of operating an addressable field-emission array, includes: generating a plurality of electron beams from a pluralitly of emitters that compose the addressable field-emission array; and focusing at least one of the plurality of electron beams with an on-chip electrostatic focusing stack. The systems and methods provide advantages including the avoidance of space-charge blow-up.

  6. Communication, Systems, and Misconduct with Adolescent Students

    ERIC Educational Resources Information Center

    Hargrave, Terry D.; Brammer, Robert

    2006-01-01

    This article examines communication and system issues in dealing with misconduct in adolescents. The initial focus is an analysis of the goals of misconduct, including attention, power, revenge, and display of inadequacy. The second focus encourages the school system to consider its own part in the problems of misconduct, by examining circular…

  7. ESIF: Bring Us Your Challenges

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    2016-08-01

    This brochure highlights the Energy Systems Integration Facility (ESIF) -- the United States' premier lab focused on energy systems research, development, and demonstration (RD&D). Topics covered include an overview of Energy Systems Integration, research focus areas, RD&D tools unique to the ESIF, and information on how to partner with NREL at the ESIF.

  8. Note: Automated optical focusing on encapsulated devices for scanning light stimulation systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bitzer, L. A.; Benson, N., E-mail: niels.benson@uni-due.de; Schmechel, R.

    Recently, a scanning light stimulation system with an automated, adaptive focus correction during the measurement was introduced. Here, its application on encapsulated devices is discussed. This includes the changes an encapsulating optical medium introduces to the focusing process as well as to the subsequent light stimulation measurement. Further, the focusing method is modified to compensate for the influence of refraction and to maintain a minimum beam diameter on the sample surface.

  9. Design of a new type synchronous focusing mechanism

    NASA Astrophysics Data System (ADS)

    Zhang, Jintao; Tan, Ruijun; Chen, Zhou; Zhang, Yongqi; Fu, Panlong; Qu, Yachen

    2018-05-01

    Aiming at the dual channel telescopic imaging system composed of infrared imaging system, low-light-level imaging system and image fusion module, In the fusion of low-light-level images and infrared images, it is obvious that using clear source images is easier to obtain high definition fused images. When the target is imaged at 15m to infinity, focusing is needed to ensure the imaging quality of the dual channel imaging system; therefore, a new type of synchronous focusing mechanism is designed. The synchronous focusing mechanism realizes the focusing function through the synchronous translational imaging devices, mainly including the structure of the screw rod nut, the shaft hole coordination structure and the spring steel ball eliminating clearance structure, etc. Starting from the synchronous focusing function of two imaging devices, the structure characteristics of the synchronous focusing mechanism are introduced in detail, and the focusing range is analyzed. The experimental results show that the synchronous focusing mechanism has the advantages of ingenious design, high focusing accuracy and stable and reliable operation.

  10. Servo-controlled intravital microscope system

    NASA Technical Reports Server (NTRS)

    Mansour, M. N.; Wayland, H. J.; Chapman, C. P. (Inventor)

    1975-01-01

    A microscope system is described for viewing an area of a living body tissue that is rapidly moving, by maintaining the same area in the field-of-view and in focus. A focus sensing portion of the system includes two video cameras at which the viewed image is projected, one camera being slightly in front of the image plane and the other slightly behind it. A focus sensing circuit for each camera differentiates certain high frequency components of the video signal and then detects them and passes them through a low pass filter, to provide dc focus signal whose magnitudes represent the degree of focus. An error signal equal to the difference between the focus signals, drives a servo that moves the microscope objective so that an in-focus view is delivered to an image viewing/recording camera.

  11. Slanted-edge MTF testing for establishing focus alignment at infinite conjugate of space optical systems with gravity sag effects

    NASA Astrophysics Data System (ADS)

    Newswander, T.; Riesland, David W.; Miles, Duane; Reinhart, Lennon

    2017-09-01

    For space optical systems that image extended scenes such as earth-viewing systems, modulation transfer function (MTF) test data is directly applicable to system optical resolution. For many missions, it is the most direct metric for establishing the best focus of the instrument. Additionally, MTF test products can be combined to predict overall imaging performance. For fixed focus instruments, finding the best focus during ground testing is critical to achieving good imaging performance. The ground testing should account for the full-imaging system, operational parameters, and operational environment. Testing the full-imaging system removes uncertainty caused by breaking configurations and the combination of multiple subassembly test results. For earth viewing, the imaging system needs to be tested at infinite conjugate. Operational environment test conditions should include temperature and vacuum. Optical MTF testing in the presence of operational vibration and gravity release is less straightforward and may not be possible on the ground. Gravity effects are mitigated by testing in multiple orientations. Many space telescope systems are designed and built to have optimum performance in a gravity-free environment. These systems can have imaging performance that is dominated by aberration including astigmatism. This paper discusses how the slanted edge MTF test is applied to determine the best focus of a space optical telescope in ground testing accounting for gravity sag effects. Actual optical system test results and conclusions are presented.

  12. Lightweight diaphragm mirror module system for solar collectors

    DOEpatents

    Butler, Barry L.

    1985-01-01

    A mirror module system is provided for accurately focusing solar radiation on a point or a line as defined by an array of solar collectors. Each mirror module includes a flexible membrane stretched over a frame in a manner similar to that of a drum or a trampoline and further includes a silvered glass or plastic mirror for forming an optical reflecting surface. The configuration of the optical reflecting surface is variably adjustable to provide for the accurate focusing of the solar energy on a given collector array, e.g., a point or a linear array arrangement. The flexible mirror-membrane combination is lightweight to facilitate installation and reduce system cost yet structurally strong enough to provide for the precise focusing of the incident solar radiation in a semi-rigid reflector system in which unwanted reflector displacement is minimized.

  13. Lightweight diaphragm mirror module system for solar collectors

    DOEpatents

    Butler, B.L.

    1984-01-01

    A mirror module system is provided for accurately focusing solar radiation on a point or a line as defined by an array of solar collectors. Each mirror module includes a flexible membrane stretched over a frame in a manner similar to that of a drum or a trampoline and further includes a silvered glass or plastic mirror for forming an optical reflecting surface. The configuration of the optical reflecting surface is variably adjustable to provide for the accurate focusing of the solar energy on a given collector array, e.g., a point or a linear array arrangement. The flexible mirror-membrane combination is lightweight to facilitate installation and reduce system cost yet structurally strong enough to provide for the precise focusing of the incident solar radiation in a semi-rigid reflector system in which unwanted reflector displacement is minimized.

  14. The Polish School System. Some Social and Historical Aspects.

    ERIC Educational Resources Information Center

    Holmberg, Carl, Ed.; Wojtowicz, Wit J., Ed.

    A description of the Polish school-system and current educational research at the University of Gdansk (Poland) are included in this document. Articles included focus on two perspectives: (1) the social context in which schooling takes place; and (2) a historical outlook of the Polish system of education. Articles in this volume include:…

  15. Method for pulse control in a laser including a stimulated brillouin scattering mirror system

    DOEpatents

    Dane, C. Brent; Hackel, Lloyd; Harris, Fritz B.

    2007-10-23

    A laser system, such as a master oscillator/power amplifier system, comprises a gain medium and a stimulated Brillouin scattering SBS mirror system. The SBS mirror system includes an in situ filtered SBS medium that comprises a compound having a small negative non-linear index of refraction, such as a perfluoro compound. An SBS relay telescope having a telescope focal point includes a baffle at the telescope focal point which blocks off angle beams. A beam splitter is placed between the SBS mirror system and the SBS relay telescope, directing a fraction of the beam to an alternate beam path for an alignment fiducial. The SBS mirror system has a collimated SBS cell and a focused SBS cell. An adjustable attenuator is placed between the collimated SBS cell and the focused SBS cell, by which pulse width of the reflected beam can be adjusted.

  16. Optical diagnostics integrated with laser spark delivery system

    DOEpatents

    Yalin, Azer [Fort Collins, CO; Willson, Bryan [Fort Collins, CO; Defoort, Morgan [Fort Collins, CO; Joshi, Sachin [Fort Collins, CO; Reynolds, Adam [Fort Collins, CO

    2008-09-02

    A spark delivery system for generating a spark using a laser beam is provided, and includes a laser light source and a laser delivery assembly. The laser delivery assembly includes a hollow fiber and a launch assembly comprising launch focusing optics to input the laser beam in the hollow fiber. The laser delivery assembly further includes exit focusing optics that demagnify an exit beam of laser light from the hollow fiber, thereby increasing the intensity of the laser beam and creating a spark. Other embodiments use a fiber laser to generate a spark. Embodiments of the present invention may be used to create a spark in an engine. Yet other embodiments include collecting light from the spark or a flame resulting from the spark and conveying the light for diagnostics. Methods of using the spark delivery systems and diagnostic systems are provided.

  17. Fiber laser coupled optical spark delivery system

    DOEpatents

    Yalin, Azer [Fort Collins, CO; Willson, Bryan [Fort Collins, CO; Defoort, Morgan [Fort Collins, CO; Joshi, Sachin [Fort Collins, CO; Reynolds, Adam [Fort Collins, CO

    2008-03-04

    A spark delivery system for generating a spark using a laser beam is provided, and includes a laser light source and a laser delivery assembly. The laser delivery assembly includes a hollow fiber and a launch assembly comprising launch focusing optics to input the laser beam in the hollow fiber. The laser delivery assembly further includes exit focusing optics that demagnify an exit beam of laser light from the hollow fiber, thereby increasing the intensity of the laser beam and creating a spark. Other embodiments use a fiber laser to generate a spark. Embodiments of the present invention may be used to create a spark in an engine. Yet other embodiments include collecting light from the spark or a flame resulting from the spark and conveying the light for diagnostics. Methods of using the spark delivery systems and diagnostic systems are provided.

  18. Performance prediction evaluation of ceramic materials in point-focusing solar receivers

    NASA Technical Reports Server (NTRS)

    Ewing, J.; Zwissler, J.

    1979-01-01

    A performance prediction was adapted to evaluate the use of ceramic materials in solar receivers for point focusing distributed applications. System requirements were determined including the receiver operating environment and system operating parameters for various engine types. Preliminary receiver designs were evolved from these system requirements. Specific receiver designs were then evaluated to determine material functional requirements.

  19. NASA Tech Briefs, October 1995. Volume 19, No. 10

    NASA Technical Reports Server (NTRS)

    1995-01-01

    A special focus in this issue is Data acquisition and analysis. Topics covered include : Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Life Sciences; Mechanics; Machinery; Fabrication Technology; and Mathematics and Information Sciences. Also included in this issue are Laser Tech Briefs and Industry Focus: Motion Control/ Positioning Equipment

  20. Solar thermal power systems point-focusing thermal and electric applications projects. Volume 1: Executive summary

    NASA Technical Reports Server (NTRS)

    Marriott, A.

    1980-01-01

    The activities of the Point-Focusing Thermal and Electric Applications (PETEA) project for the fiscal year 1979 are summarized. The main thrust of the PFTEA Project, the small community solar thermal power experiment, was completed. Concept definition studies included a small central receiver approach, a point-focusing distributed receiver system with central power generation, and a point-focusing distributed receiver concept with distributed power generation. The first experiment in the Isolated Application Series was initiated. Planning for the third engineering experiment series, which addresses the industrial market sector, was also initiated. In addition to the experiment-related activities, several contracts to industry were let and studies were conducted to explore the market potential for point-focusing distributed receiver (PFDR) systems. System analysis studies were completed that looked at PFDR technology relative to other small power system technology candidates for the utility market sector.

  1. Microwave power transmission system studies. Volume 2: Introduction, organization, environmental and spaceborne systems analyses

    NASA Technical Reports Server (NTRS)

    Maynard, O. E.; Brown, W. C.; Edwards, A.; Haley, J. T.; Meltz, G.; Howell, J. M.; Nathan, A.

    1975-01-01

    Introduction, organization, analyses, conclusions, and recommendations for each of the spaceborne subsystems are presented. Environmental effects - propagation analyses are presented with appendices covering radio wave diffraction by random ionospheric irregularities, self-focusing plasma instabilities and ohmic heating of the D-region. Analyses of dc to rf conversion subsystems and system considerations for both the amplitron and the klystron are included with appendices for the klystron covering cavity circuit calculations, output power of the solenoid-focused klystron, thermal control system, and confined flow focusing of a relativistic beam. The photovoltaic power source characteristics are discussed as they apply to interfacing with the power distribution flow paths, magnetic field interaction, dc to rf converter protection, power distribution including estimates for the power budget, weights, and costs. Analyses for the transmitting antenna consider the aperture illumination and size, with associated efficiencies and ground power distributions. Analyses of subarray types and dimensions, attitude error, flatness, phase error, subarray layout, frequency tolerance, attenuation, waveguide dimensional tolerances, mechanical including thermal considerations are included. Implications associated with transportation, assembly and packaging, attitude control and alignment are discussed. The phase front control subsystem, including both ground based pilot signal driven adaptive and ground command approaches with their associated phase errors, are analyzed.

  2. Spacecraft Power Systems Engineering: Solutions for NASA's Manned Space Program

    NASA Technical Reports Server (NTRS)

    Scott, John H.

    2007-01-01

    An overview of spacecraft power systems is presented, with a focus on applications in the manned space program. The topics include: 1) History; 2) State-of-the-art; 3) Development directions; 4) Focus on applications in the manned space program led from JSC; 5) Power Systems Engineering Trade Space; 6) Power Generation and Energy Storage; 7) Power Distribution and Control; and 8) Actuation

  3. Criteria for Selecting Types of Foreign-Language Laboratory Systems. ERIC Focus Reports on the Teaching of Foreign Languages, Number 20.

    ERIC Educational Resources Information Center

    Hutchinson, Joseph C.; Hutchinson, June O.

    Focusing on the current status of the language laboratory in instructional use, this report stresses the need to employ a systems approach in the selection and operation of laboratory equipment. The author points out the interrelatedness of the key factors in any system, including: (1) people, (2) method, (3) instructional materials, (4)…

  4. Individually addressable cathodes with integrated focusing stack or detectors

    DOEpatents

    Thomas, Clarence E.; Baylor, Larry R.; Voelkl, Edgar; Simpson, Michael L.; Paulus, Michael J.; Lowndes, Douglas; Whealton, John; Whitson, John C.; Wilgen, John B.

    2005-07-12

    Systems and method are described for addressable field emission array (AFEA) chips. A plurality of individually addressable cathodes are integrated with an electrostatic focusing stack and/or a plurality of detectors on the addressable field emission array. The systems and methods provide advantages including the avoidance of space-charge blow-up.

  5. Close Up Special Focus: U.S.-Soviet Relations.

    ERIC Educational Resources Information Center

    Hess, Jacqueline

    Designed to accompany a 4-part video series, this high school unit on U.S.-Soviet relations focuses on each nation's world view, political system, and ideologies. A student handbook and teacher's curriculum guide are included. The student handbook is divided into four chapters. Chapter 1 examines the political and economic system of each country…

  6. A new array system for multiphysics (MT, LOTEM, and microseismics) with focus on reservoir monitoring

    NASA Astrophysics Data System (ADS)

    Strack, K.; Davydycheva, S.; Hanstein, T.; Smirnov, M.

    2017-07-01

    Over the last 6 years we developed an array system for electromagnetic acquisition (magnetotelluric & long offset transient electromagnetics [LOTEM]) that includes microseismic acquisition. While predominantly used for magnetotellurics, we focus on the autonomous operation as reservoir monitoring system including a shallow borehole receiver and 100/150 KVA transmitter. A marine extension is also under development. For Enhanced Oil recovery (EOR), in addition to reservoir flood front movements, reservoir seal integrity has become an issue [1]. Seal integrity is best addressed with microseismics while the water flood front is best addressed with electromagnetics. Since the flooded reservoir is conductive and the hydrocarbon saturated part is resistive, you need both magnetic and electric fields. The fluid imaging is addressed using electromagnetics. To overcome the volume-focus inherent to electromagnetics a new methodology to focus the sensitivity under the receiver is proposed. Field data and 3D modeling confirm this could increase the efficiency of LOTEM to reservoir monitoring.

  7. Physicians' opinions of a health information exchange.

    PubMed

    Hincapie, Ana Lucia; Warholak, Terri L; Murcko, Anita C; Slack, Marion; Malone, Daniel C

    2011-01-01

    Arizona Medicaid developed a Health Information Exchange (HIE) system called the Arizona Medical Information Exchange (AMIE). To evaluate physicians' perceptions regarding AMIE's impact on health outcomes and healthcare costs. A focus-group guide was developed and included five domains: perceived impact of AMIE on (1) quality of care; (2) workflow and efficiency; (3) healthcare costs; (4) system usability; and (5) AMIE data content. Qualitative data were analyzed using analytical coding. A total of 29 clinicians participated in the study. The attendance rate was 66% (N=19) for the first and last month of focus-group meetings and 52% (N=15) for the focus group meetings conducted during the second month. The benefits most frequently mentioned during the focus groups included: (1) identification of "doctor shopping"; (2) averting duplicative testing; and (3) increased efficiency of clinical information gathering. The most frequent disadvantage mentioned was the limited availability of data in the AMIE system. Respondents reported that AMIE had the potential to improve care, but they felt that AMIE impact was limited due to the data available.

  8. Advanced Life Support Systems

    NASA Technical Reports Server (NTRS)

    Barta, Daniel J.

    2004-01-01

    This presentation is planned to be a 10-15 minute "catalytic" focused presentation to be scheduled during one of the working sessions at the TIM. This presentation will focus on Advanced Life Support technologies key to future human Space Exploration as outlined in the Vision, and will include basic requirements, assessment of the state-of-the-art and gaps, and include specific technology metrics. The presentation will be technical in character, lean heavily on data in published ALS documents (such as the Baseline Values and Assumptions Document) but not provide specific technical details or build to information on any technology mentioned (thus the presentation will be benign from an export control and a new technology perspective). The topics presented will be focused on the following elements of Advanced Life Support: air revitalization, water recovery, waste management, thermal control, habitation systems, food systems and bioregenerative life support.

  9. Analysis of a SCADA System Anomaly Detection Model Based on Information Entropy

    DTIC Science & Technology

    2014-03-27

    20 Intrusion Detection...alarms ( Rem ). ............................................................................................................. 86 Figure 25. TP% for...literature concerning the focus areas of this research. The focus areas include SCADA vulnerabilities, information theory, and intrusion detection

  10. System safety education focused on system management

    NASA Technical Reports Server (NTRS)

    Grose, V. L.

    1971-01-01

    System safety is defined and characteristics of the system are outlined. Some of the principle characteristics include role of humans in hazard analysis, clear language for input and output, system interdependence, self containment, and parallel analysis of elements.

  11. Design study for a two-color beta measurement system

    NASA Technical Reports Server (NTRS)

    1982-01-01

    Design analysis of the beam splitter combined two color beta system is presented. Conventional and dichroic beam splitters are discussed. Design analysis of the beta system employing two beams with focusing at separate points is presented. Alterations and basic parameters of the two beam system are discussed. Alterations in the focus of the initial laser and the returning beams are also discussed. Heterodyne efficiencies for the on axis and off axis reflected radiation are included.

  12. Practical Approaches to Resolving Behaviour Problems. Selected Papers from the National Conference on Practical Approaches to Resolving Behaviour Problems (2nd, Sydney, New South Wales, Australia, July 1990). Programs Implementation and System Initiatives.

    ERIC Educational Resources Information Center

    Richardson, Susanna, Ed.; Izard, John, Ed.

    This collection of papers focuses on practical approaches to resolving behavior problems in the Australian school system. The papers are divided into four general categories: perspectives on behavior problems, focusing on families, schools and system initiatives, and programs in special settings. The papers include: (1) "Beyond…

  13. Imaging Systems: What, When, How.

    ERIC Educational Resources Information Center

    Lunin, Lois F.; And Others

    1992-01-01

    The three articles in this special section on document image files discuss intelligent character recognition, including comparison with optical character recognition; selection of displays for document image processing, focusing on paperlike displays; and imaging hardware, software, and vendors, including guidelines for system selection. (MES)

  14. National Aeronautics and Space Administration Exploration Systems Interim Strategy

    NASA Technical Reports Server (NTRS)

    2004-01-01

    Contents include the following: 1. The Exploration Systems Mission Directorate within NASA. Enabling the Vision for Space Exploration. The Role of the Directorate. 2. Strategic Context and Approach. Corporate Focus. Focused, Prioritized Requirements. Spiral Transformation. Management Rigor. 3. Achieving Directorate Objectives. Strategy to Task Process. Capability Development. Research and Technology Development. 4. Beyond the Horizon. Appendices.

  15. Results of the Arizona Medicaid health information technology pharmacy focus groups.

    PubMed

    Warholak, Terri L; Murcko, Anita; McKee, Megan; Urbine, Terry

    2011-12-01

    In 2007, a federal Medicaid Transformation Grant was awarded to design, develop, and deploy a statewide Health Information Exchange and Electronic Health Record in Arizona, United States. To explore the health information technology needs, knowledge, and expectations of Arizona's health care professionals, moderated focus groups were conducted. This article describes the results of the pharmacist focus groups. Focus group activities included a brief presentation, completion of a paper-based survey, and group discussion. The methods included solicitation by invitation, participant selection, meeting content, collaterals, focus group execution, recording, analysis, and discerning comparability among groups. Pharmacy focus group discussions centered on electronic prescribing, including the anticipated advantages: reducing handwriting interpretation errors, improving formulary compliance, improving communication with prescribers, increasing efficiency, and ensuring data accuracy. Disadvantages included: medication errors, inadequate training and knowledge of software applications, and inflated patient expectations. Pharmacists ranked e-prescribing as the highest priority feature of an electronic health system. Copyright © 2011 Elsevier Inc. All rights reserved.

  16. Stimulated Brillouin scattering mirror system, high power laser and laser peening method and system using same

    DOEpatents

    Dane, C Brent [Livermore, CA; Hackel, Lloyd [Livermore, CA; Harris, Fritz B [Rocklin, CA

    2007-04-24

    A laser system, such as a master oscillator/power amplifier system, comprises a gain medium and a stimulated Brillouin scattering SBS mirror system. The SBS mirror system includes an in situ filtered SBS medium that comprises a compound having a small negative non-linear index of refraction, such as a perfluoro compound. An SBS relay telescope having a telescope focal point includes a baffle at the telescope focal point which blocks off angle beams. A beam splitter is placed between the SBS mirror system and the SBS relay telescope, directing a fraction of the beam to an alternate beam path for an alignment fiducial. The SBS mirror system has a collimated SBS cell and a focused SBS cell. An adjustable attenuator is placed between the collimated SBS cell and the focused SBS cell, by which pulse width of the reflected beam can be adjusted.

  17. Apparatus, systems, and methods for ultrasound synthetic aperature focusing

    DOEpatents

    Schuster, George J.; Crawford, Susan L.; Doctor, Steven R.; Harris, Robert V.

    2005-04-12

    One form of the present invention is a technique for interrogating a sample with ultrasound which includes: generating ultrasonic energy data corresponding to a volume of a sample and performing a synthetic aperture focusing technique on the ultrasonic energy data. The synthetic aperture focusing technique includes: defining a number of hyperbolic surfaces which extend through the volume at different depths and a corresponding number of multiple element accumulation vectors, performing a focused element calculation procedure for a group of vectors which are representative of the interior of a designated aperture, performing another focused element calculation procedure for vectors corresponding to the boundary of the aperture, and providing an image corresponding to features of the sample in accordance with the synthetic aperture focusing technique.

  18. Building STEM Opportunities for All

    ERIC Educational Resources Information Center

    Lynch, Sharon J.; Peters-Burton, Erin; Ford, Michael

    2015-01-01

    In response to a report from the President's Council of Advisors on Science and Technology, President Obama issued a challenge to the U.S. education system to create more than 1,000 new STEM-focused schools, including 200 high schools. Inclusive STEM-focused high schools--which focus their efforts on females, minorities, and students who are…

  19. Managing Academic Staff in Changing University Systems: International Trends and Comparisons.

    ERIC Educational Resources Information Center

    Farnham, David, Ed.

    This collection of 17 essays focuses on how faculty are employed, rewarded, and managed at universities in developed and developing nations. The essays, which include an introduction, 10 essays discussing European practices, two that focus on Canada and the United States, three which focus on Australia, Japan, and Malaysia, and a concluding…

  20. Focus Upon Implementing the GGOS Decadal Vision for Geohazards Monitoring

    NASA Astrophysics Data System (ADS)

    LaBrecque, John; Stangl, Gunter

    2017-04-01

    The Global Geodetic Observing System of the IAG identified present and future roles for Geodesy in the development and well being of the global society. The GGOS is focused upon the development of infrastructure, information, analysis, and educational systems to advance the International Global Reference Frame, the International Celestial Reference System, the International Height Reference System, atmospheric dynamics, sea level change and geohazards monitoring. The geohazards initiative is guided by an eleven nation working group initially focused upon the development and integration of regional multi-GNSS networks and analysis systems for earthquake and tsunami early warning. The opportunities and challenges being addressed by the Geohazards working group include regional network design, algorithm development and implementation, communications, funding, and international agreements on data access. This presentation will discuss in further detail these opportunities and challenges for the GGOS focus upon earthquake and tsunami early warning.

  1. Henry Ford Health Systems

    Cancer.gov

    Henry Ford Health Systems evolved from a hospital into a system delivering care to 2.5 million patients and includes the Cancer Epidemiology, Prevention and Control Program, which focuses on epidemiologic and public health aspects of cancer.

  2. Fiber coupled optical spark delivery system

    DOEpatents

    Yalin, Azer; Willson, Bryan; Defoort, Morgan

    2008-08-12

    A spark delivery system for generating a spark using a laser beam is provided, the spark delivery system including a laser light source and a laser delivery assembly. The laser delivery assembly includes a hollow fiber and a launch assembly comprising launch focusing optics to input the laser beam in the hollow fiber. In addition, the laser delivery assembly includes exit focusing optics that demagnify an exit beam of laser light from the hollow fiber, thereby increasing the intensity of the laser beam and creating a spark. In accordance with embodiments of the present invention, the assembly may be used to create a spark in a combustion engine. In accordance with other embodiments of the present invention, a method of using the spark delivery system is provided. In addition, a method of choosing an appropriate fiber for creating a spark using a laser beam is also presented.

  3. Roles of Human Factors and Ergonomics in Meeting the Challenge of Terrorism

    ERIC Educational Resources Information Center

    Nickerson, Raymond S.

    2011-01-01

    Human factors and ergonomics research focuses on questions pertaining to the design of devices, systems, and procedures with the goal of making sure that they are well suited to human use and focuses on studies of the interaction of people with simple and complex systems and machines. Problem areas studied include the allocation of function to…

  4. Fuzzy control system for a remote focusing microscope

    NASA Astrophysics Data System (ADS)

    Weiss, Jonathan J.; Tran, Luc P.

    1992-01-01

    Space Station Crew Health Care System procedures require the use of an on-board microscope whose slide images will be transmitted for analysis by ground-based microbiologists. Focusing of microscope slides is low on the list of crew priorities, so NASA is investigating the option of telerobotic focusing controlled by the microbiologist on the ground, using continuous video feedback. However, even at Space Station distances, the transmission time lag may disrupt the focusing process, severely limiting the number of slides that can be analyzed within a given bandwidth allocation. Substantial time could be saved if on-board automation could pre-focus each slide before transmission. The authors demonstrate the feasibility of on-board automatic focusing using a fuzzy logic ruled-based system to bring the slide image into focus. The original prototype system was produced in under two months and at low cost. Slide images are captured by a video camera, then digitized by gray-scale value. A software function calculates an index of 'sharpness' based on gray-scale contrasts. The fuzzy logic rule-based system uses feedback to set the microscope's focusing control in an attempt to maximize sharpness. The systems as currently implemented performs satisfactorily in focusing a variety of slide types at magnification levels ranging from 10 to 1000x. Although feasibility has been demonstrated, the system's performance and usability could be improved substantially in four ways: by upgrading the quality and resolution of the video imaging system (including the use of full color); by empirically defining and calibrating the index of image sharpness; by letting the overall focusing strategy vary depending on user-specified parameters; and by fine-tuning the fuzzy rules, set definitions, and procedures used.

  5. Observing System Simulation Experiments: An Overview

    NASA Technical Reports Server (NTRS)

    Prive, Nikki C.; Errico, Ronald M.

    2016-01-01

    An overview of Observing System Simulation Experiments (OSSEs) will be given, with focus on calibration and validation of OSSE frameworks. Pitfalls and practice will be discussed, including observation error characteristics, incestuousness, and experimental design. The potential use of OSSEs for investigation of the behaviour of data assimilation systems will be explored, including some results from experiments using the NASAGMAO OSSE.

  6. Physicians' opinions of a health information exchange

    PubMed Central

    Warholak, Terri L; Murcko, Anita C; Slack, Marion; Malone, Daniel C

    2010-01-01

    Background Arizona Medicaid developed a Health Information Exchange (HIE) system called the Arizona Medical Information Exchange (AMIE). Objective To evaluate physicians' perceptions regarding AMIE's impact on health outcomes and healthcare costs. Measurements A focus-group guide was developed and included five domains: perceived impact of AMIE on (1) quality of care; (2) workflow and efficiency; (3) healthcare costs; (4) system usability; and (5) AMIE data content. Qualitative data were analyzed using analytical coding. Results A total of 29 clinicians participated in the study. The attendance rate was 66% (N=19) for the first and last month of focus-group meetings and 52% (N=15) for the focus group meetings conducted during the second month. The benefits most frequently mentioned during the focus groups included: (1) identification of “doctor shopping”; (2) averting duplicative testing; and (3) increased efficiency of clinical information gathering. The most frequent disadvantage mentioned was the limited availability of data in the AMIE system. Conclusion Respondents reported that AMIE had the potential to improve care, but they felt that AMIE impact was limited due to the data available. PMID:21106994

  7. EMP/GMD Phase 0 Report, A Review of EMP Hazard Environments and Impacts

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rivera, Michael Kelly; Backhaus, Scott N.; Woodroffe, Jesse Richard

    The purpose of this study is to determine methods to analyze the hazard environments, impacts, and consequences of different sources of electromagnetic pulse (EMP), including nuclear electromagnetic pulse (NEMP) and geomagnetic disturbance (GMD) on the U.S. electric power infrastructures and to use those methods to determine EMP and GMD events of concern. The study will be carried out in four phases, each of which will provide higher levels of analytic fidelity that focuses on those EMP/GMD sources and events that create significant consequences, or whose consequences are sufficiently uncertain, to require more in-depth study. This study will leverage the bestmore » experimental data; device, equipment and system models; and simulation tools currently available. This study focuses primarily on the bulk electric system (BES) including large generating stations, large power transformers, the transmission network, and transmission system protection. Electrical distribution systems may potentially be included, if warranted, after consideration of the consequences for the bulk power system.« less

  8. FOCUS: A State-Wide Initiative to Select and Retain Transition Teachers

    ERIC Educational Resources Information Center

    Cobia, Debra C.; Stephens, Cynthia E.; Sherer, Gail

    2015-01-01

    Through Focus on Change in Understanding Staff and Staffing Systems in Georgia Public Schools (FOCUS), over 500 teachers of record were recruited, selected, and placed in Georgia's high-need schools. Teachers in the first three cohorts were retained at very high levels as well as achieving full certification. Project outcomes also included the…

  9. Thermal Power Systems (TPS); Point-Focusing Thermal and Electric Applications (PFTEA). Volume 2: Detailed report, fiscal year 1979

    NASA Technical Reports Server (NTRS)

    1980-01-01

    Progress in the development of systems which employ point focusing distributed receiver technology is reported. Emphasis is placed on the first engineering experiment, the Small Community Solar Thermal Power Experiment. Procurement activities for the Military Module Power Experiment the first of a series of experiments planned as part of the Isolated Load Series are included.

  10. Leadership Matters: Supporting Administrators through First Year Implementation of a Standards-Based Evaluation System in a Small Urban School District

    ERIC Educational Resources Information Center

    Esmont, Leah W.

    2014-01-01

    Education policymakers at the national level have initiated reforms in K-12 education for that past several years that have focused on teacher quality and teacher evaluation. More recently, reforms have included legislation that focuses on administrator quality as well. Included in far-reaching recent legislation in Arizona is a requirement that…

  11. Data Assimilation and Predictability Studies on Typhoon Sinlaku (2008) Using the WRF-LETKF System

    NASA Astrophysics Data System (ADS)

    Miyoshi, T.; Kunii, M.

    2011-12-01

    Data assimilation and predictability studies on Tropical Cyclones with a particular focus on intensity forecasts are performed with the newly-developed Local Ensemble Transform Kalman Filter (LETKF) system with the WRF model. Taking advantage of intensive observations of the internationally collaborated T-PARC (THORPEX Pacific Asian Regional Campaign) project, we focus on Typhoon Sinlaku (2008) which intensified rapidly before making landfall to Taiwan. This study includes a number of data assimilation experiments, higher-resolution forecasts, and sensitivity analysis which quantifies impacts of observations on forecasts. This presentation includes latest achievements up to the time of the conference.

  12. The Voice as Computer Interface: A Look at Tomorrow's Technologies.

    ERIC Educational Resources Information Center

    Lange, Holley R.

    1991-01-01

    Discussion of voice as the communications device for computer-human interaction focuses on voice recognition systems for use within a library environment. Voice technologies are described, including voice response and voice recognition; examples of voice systems in use in libraries are examined; and further possibilities, including use with…

  13. Domains of the Florida Performance Measurement System.

    ERIC Educational Resources Information Center

    Florida State Dept. of Education, Tallahassee.

    This monograph sets forth in detail the concepts included in the five domains of teaching as identified by the Florida Coalition for the Development of a Performance Evaluation System. The first domain, planning, includes the concepts: (1) content coverage; (2) utilization of instructional materials; (3) activity structure; (4) goal focusing; and…

  14. Management Styles and Techniques: People.

    ERIC Educational Resources Information Center

    DeLoach, Marva L.; And Others

    1987-01-01

    Three articles discuss management of library technical processes personnel. The first article focuses on the employer employee relationship and communication; the second explores management trends, including participative decision making, personnel evaluation, management by objectives, and the collegial system; and the third focuses on the…

  15. A review of HIV/AIDS system-level interventions

    PubMed Central

    Bauermeister, José A.; Tross, Susan; Ehrhardt, Anke A.

    2010-01-01

    The escalating HIV/AIDS epidemic worldwide demands that on-going prevention efforts be strengthened, disseminated, and scaled-up. System-level interventions refer to programs aiming to improve the functioning of an agency as well as the delivery of its services to the community. System-level interventions are a promising approach to HIV/AIDS prevention because they focus on (a) improving the agency’s ability to adopt evidence-based HIV prevention and care programs; (b) develop and establish policies and procedures that maximize the sustainability of on-going prevention and care efforts; and (c) improve decision-making processes such as incorporating the needs of communities into their tailored services. We reviewed studies focusing on system-level interventions by searching multiple electronic abstracting indices, including PsycInfo, PubMed, and ProQuest. Twenty-three studies out of 624 peer-reviewed studies (published from January 1985 to February 2007) met study criteria. Most of the studies focused on strengthening agency infrastructure, while other studies included collaborative partnerships and technical assistance programs. Our findings suggest that system-level interventions are promising in strengthening HIV/AIDS prevention and treatment efforts. Based on our findings, we propose recommendations for future work in developing and evaluating system-level interventions. PMID:18369722

  16. Using global health initiatives to strengthen health systems: a civil society perspective.

    PubMed

    Cohn, Jennifer; Russell, Asia; Baker, Brook; Kayongo, Alice; Wanjiku, Esther; Davis, Paul

    2011-01-01

    Research into the effects of global health initiatives (GHIs) on health systems has largely left out the viewpoints and contributions of civil society. This study details civil society's perspective regarding the effects of two GHIs, the US President's Emergency Plan for AIDS Relief (PEPFAR) and the Global Fund to Fight AIDS, Tuberculosis and Malaria (GFATM), on country health systems and the added value of civil society interacting with GHIs to strengthen health systems. The study employed qualitative data collection methods using semi-structured interviews administered during focus groups and key informant interviews. A range of health system stakeholders were interviewed in Kenya, Malawi, Uganda and Zambia. Data were coded and analysed for themes and sub-themes. In total, 2910 civil society participants provided information individually or in focus groups. Respondents reported that GHIs have contributed to dramatic health benefits within and outside of a disease-specific focus, including health systems strengthening efforts. However, opportunities for synergy between GHIs and health systems have been missed, and GHIs have not worked sufficiently to close capacity gaps of grassroots civil society organisations. Despite some governance innovations, civil society's opportunities to participate meaningfully in GHI priority setting efforts are limited. Recommendations are included on how to best use GHIs to strengthen health systems by partnering with civil society.

  17. Implementation of Enhanced Recovery After Surgery: a strategy to transform surgical care across a health system.

    PubMed

    Gramlich, Leah M; Sheppard, Caroline E; Wasylak, Tracy; Gilmour, Loreen E; Ljungqvist, Olle; Basualdo-Hammond, Carlota; Nelson, Gregg

    2017-05-19

    Enhanced Recovery After Surgery (ERAS) programs have been shown to have a positive impact on outcome. The ERAS care system includes an evidence-based guideline, an implementation program, and an interactive audit system to support practice change. The purpose of this study is to describe the use of the Theoretic Domains Framework (TDF) in changing surgical care and application of the Quality Enhancement Research Initiative (QUERI) model to analyze end-to-end implementation of ERAS in colorectal surgery across multiple sites within a single health system. The ultimate intent of this work is to allow for the development of a model for spread, scale, and sustainability of ERAS in Alberta Health Services (AHS). ERAS for colorectal surgery was implemented at two sites and then spread to four additional sites. The ERAS Interactive Audit System (EIAS) was used to assess compliance with the guidelines, length of stay, readmissions, and complications. Data sources informing knowledge translation included surveys, focus groups, interviews, and other qualitative data sources such as minutes and status updates. The QUERI model and TDF were used to thematically analyze 189 documents with 2188 quotes meeting the inclusion criteria. Data sources were analyzed for barriers or enablers, organized into a framework that included individual to organization impact, and areas of focus for guideline implementation. Compliance with the evidence-based guidelines for ERAS in colorectal surgery at baseline was 40%. Post implementation compliance, consistent with adoption of best practice, improved to 65%. Barriers and enablers were categorized as clinical practice (22%), individual provider (26%), organization (19%), external environment (7%), and patients (25%). In the Alberta context, 26% of barriers and enablers to ERAS implementation occurred at the site and unit levels, with a provider focus 26% of the time, a patient focus 26% of the time, and a system focus 22% of the time. Using the ERAS care system and applying the QUERI model and TDF allow for identification of strategies that can support diffusion and sustainment of innovation of Enhanced Recovery After Surgery across multiple sites within a health care system.

  18. Knowledge-Based Information Retrieval.

    ERIC Educational Resources Information Center

    Ford, Nigel

    1991-01-01

    Discussion of information retrieval focuses on theoretical and empirical advances in knowledge-based information retrieval. Topics discussed include the use of natural language for queries; the use of expert systems; intelligent tutoring systems; user modeling; the need for evaluation of system effectiveness; and examples of systems, including…

  19. Ponderomotive phase plate for transmission electron microscopes

    DOEpatents

    Reed, Bryan W [Livermore, CA

    2012-07-10

    A ponderomotive phase plate system and method for controllably producing highly tunable phase contrast transfer functions in a transmission electron microscope (TEM) for high resolution and biological phase contrast imaging. The system and method includes a laser source and a beam transport system to produce a focused laser crossover as a phase plate, so that a ponderomotive potential of the focused laser crossover produces a scattering-angle-dependent phase shift in the electrons of the post-sample electron beam corresponding to a desired phase contrast transfer function.

  20. Line focus concentrating collector for Copper Mountain Ski Resort, Colorado (Engineering Materials)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1983-06-02

    The present invention is a device which develops an accurate line focus concentrating collector by flexural bending of thin reflective materials. This method avoids the need for expensive tooling and support frame fabrication. The technical work conducted during this quarter included completion of designs for the prototype system for the Copper Mountain Ski Resort in Colorado. Evaluation of alternate tracking and drive systems and final design of the support system. These drawings accompany DOE/CS/15072--T4.

  1. Internal Representational Models of Attachment Relationships.

    ERIC Educational Resources Information Center

    Crittenden, Patricia M.

    This paper outlines several properties of internal representational models (IRMs) and offers terminology that may help to differentiate the models. Properties of IRMs include focus, memory systems, content, cognitive function, "metastructure," quality of attachment, behavioral strategies, and attitude toward attachment. An IRM focuses on…

  2. Laser focus compensating sensing and imaging device

    DOEpatents

    Vann, Charles S.

    1993-01-01

    A laser focus compensating sensing and imaging device permits the focus of a single focal point of different frequency laser beams emanating from the same source point. In particular it allows the focusing of laser beam originating from the same laser device but having differing intensities so that a low intensity beam will not convert to a higher frequency when passing through a conversion crystal associated with the laser generating device. The laser focus compensating sensing and imaging device uses a cassegrain system to fold the lower frequency, low intensity beam back upon itself so that it will focus at the same focal point as a high intensity beam. An angular tilt compensating lens is mounted about the secondary mirror of the cassegrain system to assist in alignment. In addition cameras or CCD's are mounted with the primary mirror to sense the focused image. A convex lens is positioned co-axial with the cassegrain system on the side of the primary mirror distal of the secondary for use in aligning a target with the laser beam. A first alternate embodiment includes a cassegrain system using a series of shutters and an internally mounted dichroic mirror. A second alternate embodiment uses two laser focus compensating sensing and imaging devices for aligning a moving tool with a work piece.

  3. Laser focus compensating sensing and imaging device

    DOEpatents

    Vann, C.S.

    1993-08-31

    A laser focus compensating sensing and imaging device permits the focus of a single focal point of different frequency laser beams emanating from the same source point. In particular it allows the focusing of laser beam originating from the same laser device but having differing intensities so that a low intensity beam will not convert to a higher frequency when passing through a conversion crystal associated with the laser generating device. The laser focus compensating sensing and imaging device uses a Cassegrain system to fold the lower frequency, low intensity beam back upon itself so that it will focus at the same focal point as a high intensity beam. An angular tilt compensating lens is mounted about the secondary mirror of the Cassegrain system to assist in alignment. In addition cameras or CCD's are mounted with the primary mirror to sense the focused image. A convex lens is positioned co-axial with the Cassegrain system on the side of the primary mirror distal of the secondary for use in aligning a target with the laser beam. A first alternate embodiment includes a Cassegrain system using a series of shutters and an internally mounted dichroic mirror. A second alternate embodiment uses two laser focus compensating sensing and imaging devices for aligning a moving tool with a work piece.

  4. Chronic disease management: time for consultant physicians to take more leadership in system redesign.

    PubMed

    Brand, C; Scott, I; Greenberg, P; Sargious, P

    2007-09-01

    There is a need for system redesign to meet the needs of individuals with chronic disease. New models of chronic disease care include team-based paradigms that focus on continuous and patient-centred care. In such models the roles of providers and patients must change. In this article we focus on new roles for consultant physicians, as well as barriers and incentives to these roles.

  5. Current understanding of interactions between nanoparticles and the immune system

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dobrovolskaia, Marina A., E-mail: marina@mail.nih.

    2016-05-15

    The delivery of drugs, antigens, and imaging agents benefits from using nanotechnology-based carriers. The successful translation of nanoformulations to the clinic involves thorough assessment of their safety profiles, which, among other end-points, includes evaluation of immunotoxicity. The past decade of research focusing on nanoparticle interaction with the immune system has been fruitful in terms of understanding the basics of nanoparticle immunocompatibility, developing a bioanalytical infrastructure to screen for nanoparticle-mediated immune reactions, beginning to uncover the mechanisms of nanoparticle immunotoxicity, and utilizing current knowledge about the structure–activity relationship between nanoparticles' physicochemical properties and their effects on the immune system to guidemore » safe drug delivery. In the present review, we focus on the most prominent pieces of the nanoparticle–immune system puzzle and discuss the achievements, disappointments, and lessons learned over the past 15 years of research on the immunotoxicity of engineered nanomaterials. - Graphical abstract: API — active pharmaceutical ingredient; NP — nanoparticles; PCP — physicochemical properties, CARPA — complement activation-related pseudoallergy, ICH — International Conference on Harmonization. Display Omitted - Highlights: • Achievements, disappointments and lessons learned over past decade are reviewed. • Areas in focus include characterization, immunotoxicity and utility in drug delivery. • Future direction focusing on mechanistic immunotoxicity studies is proposed.« less

  6. Systems metabolic engineering strategies for the production of amino acids.

    PubMed

    Ma, Qian; Zhang, Quanwei; Xu, Qingyang; Zhang, Chenglin; Li, Yanjun; Fan, Xiaoguang; Xie, Xixian; Chen, Ning

    2017-06-01

    Systems metabolic engineering is a multidisciplinary area that integrates systems biology, synthetic biology and evolutionary engineering. It is an efficient approach for strain improvement and process optimization, and has been successfully applied in the microbial production of various chemicals including amino acids. In this review, systems metabolic engineering strategies including pathway-focused approaches, systems biology-based approaches, evolutionary approaches and their applications in two major amino acid producing microorganisms: Corynebacterium glutamicum and Escherichia coli, are summarized.

  7. Potential and problems in ultrasound-responsive drug delivery systems

    PubMed Central

    Zhao, Ying-Zheng; Du, Li-Na; Lu, Cui-Tao; Jin, Yi-Guang; Ge, Shu-Ping

    2013-01-01

    Ultrasound is an important local stimulus for triggering drug release at the target tissue. Ultrasound-responsive drug delivery systems (URDDS) have become an important research focus in targeted therapy. URDDS include many different formulations, such as microbubbles, nanobubbles, nanodroplets, liposomes, emulsions, and micelles. Drugs that can be loaded into URDDS include small molecules, biomacromolecules, and inorganic substances. Fields of clinical application include anticancer therapy, treatment of ischemic myocardium, induction of an immune response, cartilage tissue engineering, transdermal drug delivery, treatment of Huntington’s disease, thrombolysis, and disruption of the blood–brain barrier. This review focuses on recent advances in URDDS, and discusses their formulations, clinical application, and problems, as well as a perspective on their potential use in the future. PMID:23637531

  8. Imaging based refractometer for hyperspectral refractive index detection

    DOEpatents

    Baba, Justin S.; Boudreaux, Philip R.

    2015-11-24

    Refractometers for simultaneously measuring refractive index of a sample over a range of wavelengths of light include dispersive and focusing optical systems. An optical beam including the range of wavelengths is spectrally spread along a first axis and focused along a second axis so as to be incident to an interface between the sample and a prism at a range of angles of incidence including a critical angle for at least one wavelength. An imaging detector is situated to receive the spectrally spread and focused light from the interface and form an image corresponding to angle of incidence as a function of wavelength. One or more critical angles are identified and corresponding refractive indices are determined.

  9. Direct-to-digital holography and holovision

    DOEpatents

    Thomas, Clarence E.; Baylor, Larry R.; Hanson, Gregory R.; Rasmussen, David A.; Voelkl, Edgar; Castracane, James; Simkulet, Michelle; Clow, Lawrence

    2000-01-01

    Systems and methods for direct-to-digital holography are described. An apparatus includes a laser; a beamsplitter optically coupled to the laser; a reference beam mirror optically coupled to the beamsplitter; an object optically coupled to the beamsplitter, a focusing lens optically coupled to both the reference beam mirror and the object; and a digital recorder optically coupled to the focusing lens. A reference beam is incident upon the reference beam mirror at a non-normal angle, and the reference beam and an object beam are focused by the focusing lens at a focal plane of the digital recorder to form an image. The systems and methods provide advantages in that computer assisted holographic measurements can be made.

  10. Virtual mask digital electron beam lithography

    DOEpatents

    Baylor, L.R.; Thomas, C.E.; Voelkl, E.; Moore, J.A.; Simpson, M.L.; Paulus, M.J.

    1999-04-06

    Systems and methods for direct-to-digital holography are described. An apparatus includes a laser; a beamsplitter optically coupled to the laser; a reference beam mirror optically coupled to the beamsplitter; an object optically coupled to the beamsplitter, a focusing lens optically coupled to both the reference beam mirror and the object; and a digital recorder optically coupled to the focusing lens. A reference beam is incident upon the reference beam mirror at a non-normal angle, and the reference beam and an object beam are focused by the focusing lens at a focal plane of the digital recorder to form an image. The systems and methods provide advantages in that computer assisted holographic measurements can be made. 5 figs.

  11. Virtual mask digital electron beam lithography

    DOEpatents

    Baylor, Larry R.; Thomas, Clarence E.; Voelkl, Edgar; Moore, James A.; Simpson, Michael L.; Paulus, Michael J.

    1999-01-01

    Systems and methods for direct-to-digital holography are described. An apparatus includes a laser; a beamsplitter optically coupled to the laser; a reference beam mirror optically coupled to the beamsplitter; an object optically coupled to the beamsplitter, a focusing lens optically coupled to both the reference beam mirror and the object; and a digital recorder optically coupled to the focusing lens. A reference beam is incident upon the reference beam mirror at a non-normal angle, and the reference beam and an object beam are focused by the focusing lens at a focal plane of the digital recorder to form an image. The systems and methods provide advantages in that computer assisted holographic measurements can be made.

  12. DEVELOPMENTAL TOXICOLOGY EVALUATIONS -- ISSUES WITH INCLUDING NEUROTOXICOLOGY AND IMMUNOTOXICOLOGY ASSESSMENTS IN REPRODUCTIVE TOXICOLOGY STUDIES

    EPA Science Inventory

    Developmental and reproductive toxixology (DART) has routinely been a part of safety assessment. Attention is now focused on the effects of chemicals on the developing nervous and immune systems. This focus on developmental neurotoxicology (DNT) and developmental immunotoxicolo...

  13. Automated System Marketplace 1993. Part I: Focus on Minicomputers.

    ERIC Educational Resources Information Center

    Bridge, Frank R.

    1993-01-01

    The first part of the annual automation marketplace survey examines minicomputer systems in libraries. Highlights include vendor consolidation and acquisitions; system interconnection; networked databases; products related to the Americans with Disabilities Act; multimedia; vendor installations worldwide; academic versus public library…

  14. Optical Character Recognition.

    ERIC Educational Resources Information Center

    Converso, L.; Hocek, S.

    1990-01-01

    This paper describes computer-based optical character recognition (OCR) systems, focusing on their components (the computer, the scanner, the OCR, and the output device); how the systems work; and features to consider in selecting a system. A list of 26 questions to ask to evaluate systems for potential purchase is included. (JDD)

  15. Document Indexing for Image-Based Optical Information Systems.

    ERIC Educational Resources Information Center

    Thiel, Thomas J.; And Others

    1991-01-01

    Discussion of image-based information retrieval systems focuses on indexing. Highlights include computerized information retrieval; multimedia optical systems; optical mass storage and personal computers; and a case study that describes an optical disk system which was developed to preserve, access, and disseminate military documents. (19…

  16. Advanced Life Support Research and Technology Development

    NASA Technical Reports Server (NTRS)

    Kliss, Mark

    2001-01-01

    A videograph outlining life support research. The Human Exploration and Development of Space (HEDS) Enterprise's goals are to provide life support self-sufficiency for human beings to carry out research and exploration productively in space, to open the door for planetary exploration, and for benefits on Earth. Topics presented include the role of NASA Ames, funding, and technical monitoring. The focused research areas discussed include air regeneration, carbon dioxide removal, Mars Life Support, water recovery, Vapor Phase Catalytic Ammonia Removal (VPCAR), solid waste treatment, and Supercritical Water Oxidation (SCWC). Focus is placed on the utilization of Systems Integration, Modeling and Analysis (SIMA) and Dynamic Systems Modeling in this research.

  17. Working appreciatively to improve services for children and families.

    PubMed

    Onyett, Steve

    2009-10-01

    Service improvement approaches are described that specifically focus on appreciating the positive that individuals bring to contexts related to children and family services. This includes application of Solution-Focused approaches, Appreciative Inquiry and other approaches that promote a positive emotional climate and focus on what works. Their conceptual foundations are explored and particularly their value in supporting working well with complex adaptive systems. Specific applications described include leadership and management practice, work in school settings, engaging clinicians in healthcare improvement, establishing clinical networks, work with homeless youth, child protection and approaches to drawing out best practice and community development. The theme that unites is a focus on developing effective relationships at all levels and a pragmatic focus on what works so that we can find opportunities to do more of it.

  18. Particle beam generator using a radioactive source

    DOEpatents

    Underwood, D.G.

    1993-03-30

    The apparatus of the present invention selects from particles emitted by a radioactive source those particles having momentum within a desired range and focuses the selected particles in a beam having at least one narrow cross-dimension, and at the same time attenuates potentially disruptive gamma rays and low energy particles. Two major components of the present invention are an achromatic bending and focusing system, which includes sector magnets and quadrupole, and a quadrupole doublet final focus system. Permanent magnets utilized in the apparatus are constructed of a ceramic (ferrite) material which is inexpensive and easily machined.

  19. Particle beam generator using a radioactive source

    DOEpatents

    Underwood, David G.

    1993-01-01

    The apparatus of the present invention selects from particles emitted by a radioactive source those particles having momentum within a desired range and focuses the selected particles in a beam having at least one narrow cross-dimension, and at the same time attenuates potentially disruptive gamma rays and low energy particles. Two major components of the present invention are an achromatic bending and focusing system, which includes sector magnets and quadrupole, and a quadrupole doublet final focus system. Permanent magnets utilized in the apparatus are constructed of a ceramic (ferrite) material which is inexpensive and easily machined.

  20. A business model for managing system change through strategic financing and performance indicators: a case study.

    PubMed

    Armstrong, Mary I; Milch, Heidi; Curtis, Peter; Endress, Phillip

    2012-06-01

    This article describes how a system of care operated by a county government agency used a fiscal crisis as the opportunity to reform its children's system. A cross-system response to the crisis is outlined that includes a system of care framework coupled with a business model, inter-departmental collaboration and leadership, the use of strategic reinvestment strategies, and a quality improvement system that focuses on key indicators. Implementation of the system change is described with a specific focus on cross-system entry points, financing strategies that re-allocate funds from deep-end programs to community-based services, and management oversight through the use of performance indicators to monitor and support effectiveness. This article examines the results of the system change, including the diversion of youth from system penetration, the reduction in residential treatment bed days, the re-allocation of these savings to community-based services, and the outcomes of children who were diverted from residential care and served in the community. The article offers a number of recommendations for other communities contemplating system change.

  1. Square Pegs and Round Holes: Ruminations on the Relationship between Performance Appraisal and Performance Management

    ERIC Educational Resources Information Center

    Gravina, Nicole E.; Siers, Brian P.

    2011-01-01

    Models of comprehensive Performance Management systems include both employee development and evaluative components. The Organizational Behavior Management discipline focuses almost exclusively on the developmental component, while the Industrial and Organizational Psychology discipline is focused on use of performance appraisals. Performance…

  2. A Qualitative Analysis of Physician Perspectives on Missed and Delayed Outpatient Diagnosis: The Focus on System-Related Factors.

    PubMed

    Sarkar, Urmimala; Simchowitz, Brett; Bonacum, Doug; Strull, William; Lopez, Andrea; Rotteau, Leahora; Shojania, Kaveh G

    2014-10-01

    Delayed and missed diagnoses lead to significant patient harm. Because physician actions are fundamental to the outpatient diagnostic process, a study was conducted to explore physician perspectives on diagnosis. As part of a quality improvement initiative, an integrated health system conducted six physician focus groups in 2004 and 2005. The focus groups included questions about the process of diagnosis, specific factors contributing to missed diagnosis, use of guidelines, atypical vs. typical presentations of disease, diagnostic tools, and follow-up, all with regard to delays in the diagnostic process. The interviews were analyzed (1) deductively, with application of the Systems Engineering Initiative for Patient Safety (SEIPS) model, which addresses systems design, quality management, job design, and technology implementations that affect safety-related patient and organizational and/or staff outcomes, and (2) inductively, with identification of novel themes using content analysis. A total of 25 physicians participated in the six focus groups, which yielded 12 hours of discussion. Providers identified multiple barriers to timely and accurate diagnosis, including organizational culture, information availability, and communication factors. Multiple themes relating to each of the participants in the diagnostic process-health system, provider, and patient-emerged. Concerns about health system structure and providers' interactions with one another and with patients far exceeded discussion of the cognitive factors that might affect the diagnostic process. The results suggest that, at least in physicians' views, improving the diagnostic process requires attention to the organization of the health system in addition to the cognitive aspects of diagnosis.

  3. Beyond Web-Based Training: Learning Unplugged.

    ERIC Educational Resources Information Center

    Gayeski, Diane M.

    2002-01-01

    Discussion of corporate training focuses on the Internet, Web-based training, and the latest trend toward wireless technology. Topics include the emerging workplace, including continuous learning and collaboration and aiding performance; mobile delivery systems for corporate instructional designers; and types of mobile devices, including PDAs…

  4. An Evaluation of Online Help for the NOTIS OPAC.

    ERIC Educational Resources Information Center

    White, Frank

    1994-01-01

    Discussion of online help systems in online public access catalogs (OPACs) focuses on a study that evaluated the online help system for the NOTIS (Northwestern Online Total Integrated System) OPAC. Features of the system reviewed include online functions; training features; general interface features; access points; and message content and display…

  5. The Excellent Education System for One and a Half Million Children.

    ERIC Educational Resources Information Center

    Shiba, Shoji

    1986-01-01

    This description of popular private educational system in Japan, the Kumon Method, focuses on instruction in arithmetic for primary school students. Highlights include the educational philosophy of the system, instructor training, acceptance by parents, and use of the system as a model for educational systems of the future. (LRW)

  6. Proceedings of the First Semiannual Distributed Receiver Program Review

    NASA Technical Reports Server (NTRS)

    1980-01-01

    Point focus and line focus distributed receiver solar thermal technology for the production of electric power and of industrial process heat is addressed. Concentrator, receiver, and power conversion development are covered along with hardware tests and evaluation. Mass production costing, parabolic dish applications, and trough and bowl systems are included.

  7. REACH. Heating Units.

    ERIC Educational Resources Information Center

    Stanfield, Carter; And Others

    As a part of the REACH (Refrigeration, Electro-Mechanical, Air-Conditioning, Heating) electromechanical cluster, this student manual contains individualized units in the area of heating. The instructional units focus on electric heating systems, gas heating systems, and oil burning systems. Each unit follows a typical format that includes a unit…

  8. Mechatronic System Design Course for Undergraduate Programmes

    ERIC Educational Resources Information Center

    Saleem, A.; Tutunji, T.; Al-Sharif, L.

    2011-01-01

    Technology advancement and human needs have led to integration among many engineering disciplines. Mechatronics engineering is an integrated discipline that focuses on the design and analysis of complete engineering systems. These systems include mechanical, electrical, computer and control subsystems. In this paper, the importance of teaching…

  9. Computing and Systems Applied in Support of Coordinated Energy, Environmental, and Climate Planning

    EPA Science Inventory

    This talk focuses on how Dr. Loughlin is applying Computing and Systems models, tools and methods to more fully understand the linkages among energy systems, environmental quality, and climate change. Dr. Loughlin will highlight recent and ongoing research activities, including: ...

  10. Flight Performance of a Man Portable Guided Projectile Concept

    DTIC Science & Technology

    2014-02-01

    include precision guided technologies. The focus of this study is maneuvering projectiles launched from man portable weapon systems . A novel guided...5 Figure 5. Body-fixed coordinate system and aerodynamic angles...20 Figure 20. Earth and body-fixed coordinate systems and Euler angles. ........................................24

  11. Multispectral glancing incidence X-ray telescope

    NASA Technical Reports Server (NTRS)

    Hoover, Richard B. (Inventor)

    1990-01-01

    A multispectral glancing incidence X-ray telescope is illustrated capable of broadband, high-resolution imaging of solar and stellar X-ray and extreme ultraviolet radiation sources which includes a primary optical system preferably of the Wolter I type having a primary mirror system (20, 22). The primary optical system further includes an optical axis (24) having a primary focus (F1) at which the incoming radiation is focused by the primary mirrors. A plurality of ellipsoidal mirrors (30a, 30b, 30cand 30d) are carried at an inclination to the optical axis behind the primary focus (F1). A rotating carrier (32) is provided on which the ellipsoidal mirrors are carried so that a desired one of the ellipsoidal mirrors may be selectively positioned in front of the incoming radiation beam (26). In the preferred embodiment, each of the ellipsoidal mirrors has an identical concave surface carrying a layered synthetic microstructure coating tailored to reflect a desired wavelength of 1.5 .ANG. or longer. Each of the identical ellipsoidal mirrors has a second focus (F2) at which a detector (16) is carried. Thus the different wavelength image is focused upon the detector irregardless of which mirror is positioned in front of the radiation beam. In this manner, a plurality of low wavelengths in a wavelength band generally less than 30 angstroms can be imaged with a high resolution.

  12. The public transportation system security and emergency preparedness planning guide

    DOT National Transportation Integrated Search

    2003-01-01

    Recent events have focused renewed attention on the vulnerability of the nation's critical infrastructure to major events, including terrorism. The Public Transportation System Security and Emergency Preparedness Planning Guide has been prepared to s...

  13. Post-focus Instrumentation Of The NST

    NASA Astrophysics Data System (ADS)

    Cao, Wenda; Gorceix, N.; Andic, A.; Ahn, K.; Coulter, R.; Goode, P.

    2009-05-01

    The NST (New Solar Telescope), 1.6 m clear aperture, off-axis telescope, is in its commissioning phase at Big Bear Solar Observatory (BBSO). It will be the most capable, largest aperture solar telescope in the US until the 4 m ATST (Advanced Technology Solar Telescope) comes on-line in the middle of the next decade. The NST will be outfitted with state-of-the-art post-focus instrumentation, which currently include Adaptive Optics system (AO), InfraRed Imaging Magnetograph (IRIM), Visible Imaging Magnetograph (VIM), Real-time Image Reconstruction System (RIRS), and Fast Imaging Solar Spectrograph (FISS). A 308 sub-aperture (349-actuator Deformable Mirror) AO system will enable diffraction limited observations over the NST's principal operating wavelengths from 0.4 µm through 1.7 µm. IRIM and VIM are Fabry-Perot based narrow-band tunable filter, which provide high resolution two-dimensional spectroscopic and polarimetric imaging in the near infrared and visible respectively. Using a 32-node parallel computing system, RIRS is capable of performing real-time image reconstruction with one image every minute. FISS is a collaboration between NJIT and Seoul National University to focus on chromosphere dynamics. This instruments would be installed this Summer as a part of the NST commissioning and the implementation of Nysmyth focus instrumentation. Key tasks including optical design, hardware/software integration and subsequent setup/testing on the NST, will be presented in this poster. First light images from the NST will be shown.

  14. Semantic extraction and processing of medical records for patient-oriented visual index

    NASA Astrophysics Data System (ADS)

    Zheng, Weilin; Dong, Wenjie; Chen, Xiangjiao; Zhang, Jianguo

    2012-02-01

    To have comprehensive and completed understanding healthcare status of a patient, doctors need to search patient medical records from different healthcare information systems, such as PACS, RIS, HIS, USIS, as a reference of diagnosis and treatment decisions for the patient. However, it is time-consuming and tedious to do these procedures. In order to solve this kind of problems, we developed a patient-oriented visual index system (VIS) to use the visual technology to show health status and to retrieve the patients' examination information stored in each system with a 3D human model. In this presentation, we present a new approach about how to extract the semantic and characteristic information from the medical record systems such as RIS/USIS to create the 3D Visual Index. This approach includes following steps: (1) Building a medical characteristic semantic knowledge base; (2) Developing natural language processing (NLP) engine to perform semantic analysis and logical judgment on text-based medical records; (3) Applying the knowledge base and NLP engine on medical records to extract medical characteristics (e.g., the positive focus information), and then mapping extracted information to related organ/parts of 3D human model to create the visual index. We performed the testing procedures on 559 samples of radiological reports which include 853 focuses, and achieved 828 focuses' information. The successful rate of focus extraction is about 97.1%.

  15. Special Problems in the Library Setting.

    ERIC Educational Resources Information Center

    Keller, Daniel P.

    1997-01-01

    Discussion of violence in the workplace focuses on libraries. Highlights include types of violence in libraries; recognizing warning signs of employee violence; preventive action; and strategies for a safer library, including appropriate security systems and other devices. (LRW)

  16. Design Guidelines for CAI Authoring Systems.

    ERIC Educational Resources Information Center

    Hunka, S.

    1989-01-01

    Discussion of the use of authoring systems for courseware development focuses on guidelines to be considered when designing authoring systems. Topics discussed include allowing a variety of instructional strategies; interaction with peripheral processes such as student records; the editing process; and human factors in computer interface design,…

  17. Pediatric Primary Care as a Component of Systems of Care

    ERIC Educational Resources Information Center

    Brown, Jonathan D.

    2010-01-01

    Systems of care should be defined in a manner that includes primary care. The current definition of systems of care shares several attributes with the definition of primary care: both are defined as community-based services that are accessible, accountable, comprehensive, coordinated, culturally competent, and family focused. However, systems of…

  18. Space Propulsion Technology Program Overview

    NASA Technical Reports Server (NTRS)

    Escher, William J. D.

    1991-01-01

    The topics presented are covered in viewgraph form. Focused program elements are: (1) transportation systems, which include earth-to-orbit propulsion, commercial vehicle propulsion, auxiliary propulsion, advanced cryogenic engines, cryogenic fluid systems, nuclear thermal propulsion, and nuclear electric propulsion; (2) space platforms, which include spacecraft on-board propulsion, and station keeping propulsion; and (3) technology flight experiments, which include cryogenic orbital N2 experiment (CONE), SEPS flight experiment, and cryogenic orbital H2 experiment (COHE).

  19. Modular microfluidic system for biological sample preparation

    DOEpatents

    Rose, Klint A.; Mariella, Jr., Raymond P.; Bailey, Christopher G.; Ness, Kevin Dean

    2015-09-29

    A reconfigurable modular microfluidic system for preparation of a biological sample including a series of reconfigurable modules for automated sample preparation adapted to selectively include a) a microfluidic acoustic focusing filter module, b) a dielectrophoresis bacteria filter module, c) a dielectrophoresis virus filter module, d) an isotachophoresis nucleic acid filter module, e) a lyses module, and f) an isotachophoresis-based nucleic acid filter.

  20. The Network Classroom.

    ERIC Educational Resources Information Center

    Maule, R. William

    1993-01-01

    Discussion of the role of new computer communications technologies in education focuses on modern networking systems, including fiber distributed data interface and Integrated Services Digital Network; strategies for implementing networked-based communication; and public online information resources for the classroom, including Bitnet, Internet,…

  1. Measuring Family System Characteristics in Families Caring for Dementia Patients.

    ERIC Educational Resources Information Center

    Niederehe, George; And Others

    This paper describes an ongoing study evaluating families that provide in-home care to elderly relatives wth dementia. Characteristics of the study, which include a focus on progressive senile dementia, use of a clinical approach, longitudinal design, descriptive nature, focus on the dyad of patient and primary caregiver, and use of videotaping…

  2. Method of automatic measurement and focus of an electron beam and apparatus therefore

    DOEpatents

    Giedt, W.H.; Campiotti, R.

    1996-01-09

    An electron beam focusing system, including a plural slit-type Faraday beam trap, for measuring the diameter of an electron beam and automatically focusing the beam for welding is disclosed. Beam size is determined from profiles of the current measured as the beam is swept over at least two narrow slits of the beam trap. An automated procedure changes the focus coil current until the focal point location is just below a workpiece surface. A parabolic equation is fitted to the calculated beam sizes from which optimal focus coil current and optimal beam diameter are determined. 12 figs.

  3. Method of automatic measurement and focus of an electron beam and apparatus therefor

    DOEpatents

    Giedt, Warren H.; Campiotti, Richard

    1996-01-01

    An electron beam focusing system, including a plural slit-type Faraday beam trap, for measuring the diameter of an electron beam and automatically focusing the beam for welding. Beam size is determined from profiles of the current measured as the beam is swept over at least two narrow slits of the beam trap. An automated procedure changes the focus coil current until the focal point location is just below a workpiece surface. A parabolic equation is fitted to the calculated beam sizes from which optimal focus coil current and optimal beam diameter are determined.

  4. Development Activities on Airbreathing Combined Cycle Engines

    NASA Technical Reports Server (NTRS)

    McArthur, J. Craig; Lyles, Garry (Technical Monitor)

    2000-01-01

    Contents include the following: Advanced reusable transportation(ART); aerojet and rocketdyne tests, RBCC focused concept flowpaths,fabricate flight weigh, test select components, document ART project, Istar (Integrated system test of an airbreathing rocket); combined cycle propulsion testbed;hydrocarbon demonstrator tracebility; Istar engine system and vehicle system closure study; and Istar project planning.

  5. The Dental Needs and Treatment of Patients with Down Syndrome.

    PubMed

    Mubayrik, Azizah Bin

    2016-07-01

    Down syndrome is a common disorder with many oral conditions and systemic manifestations. Dentists need to take a holistic approach including behavioral, oral, and systemic issues. This review of the literature focuses on oral anomalies, systemic interaction, management, and recommendations. Copyright © 2016 Elsevier Inc. All rights reserved.

  6. A Reference and Referral System Using Expert System Techniques.

    ERIC Educational Resources Information Center

    Vickery, Alina; And Others

    1987-01-01

    Describes PLEXUS, an expert system for information retrieval related to gardening, designed at the University of London for use in public libraries. Focusing on the semantic problems encountered, methods used in artificial intelligence and information science to resolve them are discussed, including classification and facet analysis. (Author/LRW)

  7. The Changing Landscape of Grading Systems in US Higher Education

    ERIC Educational Resources Information Center

    Kleinman, Steven B.; Leidman, Mary Beth; Longcore, Andrew J.

    2018-01-01

    The following study explores the landscape of grading systems utilised in higher education, focusing on the frequency of different types of assessment scales (including Straight Letter, Plus/Minus, and other alternative policies). Although numerous studies have explored the relationship between university grading system and student behaviour,…

  8. The Integrated Library System of the 1990s: The OhioLINK Experience.

    ERIC Educational Resources Information Center

    Hawks, Carol Pitts

    1992-01-01

    Discussion of integrated library systems focuses on the development of the Ohio Library and Information Network (OhioLINK). Capabilities of eight existing systems are described, including catalog creation and maintenance; the online public access catalog (OPAC); circulation, interlibrary loan, and document delivery; acquisitions and serials…

  9. Mark Mehos | NREL

    Science.gov Websites

    Mehos Photo of Mark Mehos Mark Mehos Group Manager, Thermal Systems R&D Mark.Mehos@nrel.gov Thermal Systems R&D group at NREL, which includes the Concentrating Solar Power (CSP) Program. Since SolarPACES "Solar Thermal Electric Power Systems" task, which focuses on the development of

  10. Potential immunologic targets for treating fibrosis in systemic sclerosis: a review focused on leukocytes and cytokines.

    PubMed

    Hasegawa, Minoru; Takehara, Kazuhiko

    2012-12-01

    Systemic sclerosis (SSc) is a connective tissue disease characterized by tissue fibrosis. Although the pathogenesis remains unclear, a variety of cells contribute to the fibrotic process via interactions with each other and production of various cytokines. Recent literature related to the immunologic pathogenesis and future strategies for treating the fibrosis of SSc are discussed and, especially, this literature-based review that includes the authors' perspective, focused on leukocytes and cytokines. A PubMed search for articles published between January 2005 and January 2012 was conducted using the following keywords: systemic sclerosis, leukocyte, cytokine, growth factor, and chemokine. The reference lists of identified articles were searched for further articles. Targeting profibrogenic cytokines, including transforming growth factor-β, is still a very active area of research in SSc and most cellular studies have focused on the roles of fibroblasts in SSc. However, a growing number of recent studies indicate a role for B cells in the development of SSc and other autoimmune diseases such as systemic lupus erythematosus. Therefore, B-cell-targeted therapies, including currently available monoclonal antibodies against CD19, CD20, CD22, and B-cell-activating factor, belonging to the tumor necrosis factor family represent possible treatment options. Furthermore, the modulation of T-cell costimulatory molecules such as a recombinant fusion protein of cytotoxic T-lymphocyte antigen-4 may be as effective in SSc as it is in treating other autoimmune diseases. Approaches to antagonize interleukin (IL)-1, IL-6, or IL-17A signaling may also be attractive. This review describes recent advances in the treatment of fibrosis in SSc patients focused on immunologic strategies, such as leukocyte- or cytokine-targeted therapies. Copyright © 2012 Elsevier Inc. All rights reserved.

  11. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pacheco, J. L.; Singh, M.; Perry, D. L.

    Here, we demonstrate a capability of deterministic doping at the single atom level using a combination of direct write focused ion beam and solid-state ion detectors. The focused ion beam system can position a single ion to within 35 nm of a targeted location and the detection system is sensitive to single low energy heavy ions. This platform can be used to deterministically fabricate single atom devices in materials where the nanostructure and ion detectors can be integrated, including donor-based qubits in Si and color centers in diamond.

  12. Probabilistic Structural Analysis Methods (PSAM) for select space propulsion system components

    NASA Technical Reports Server (NTRS)

    1991-01-01

    The fourth year of technical developments on the Numerical Evaluation of Stochastic Structures Under Stress (NESSUS) system for Probabilistic Structural Analysis Methods is summarized. The effort focused on the continued expansion of the Probabilistic Finite Element Method (PFEM) code, the implementation of the Probabilistic Boundary Element Method (PBEM), and the implementation of the Probabilistic Approximate Methods (PAppM) code. The principal focus for the PFEM code is the addition of a multilevel structural dynamics capability. The strategy includes probabilistic loads, treatment of material, geometry uncertainty, and full probabilistic variables. Enhancements are included for the Fast Probability Integration (FPI) algorithms and the addition of Monte Carlo simulation as an alternate. Work on the expert system and boundary element developments continues. The enhanced capability in the computer codes is validated by applications to a turbine blade and to an oxidizer duct.

  13. Optimization of a point-focusing, distributed receiver solar thermal electric system

    NASA Technical Reports Server (NTRS)

    Pons, R. L.

    1979-01-01

    This paper presents an approach to optimization of a solar concept which employs solar-to-electric power conversion at the focus of parabolic dish concentrators. The optimization procedure is presented through a series of trade studies, which include the results of optical/thermal analyses and individual subsystem trades. Alternate closed-cycle and open-cycle Brayton engines and organic Rankine engines are considered to show the influence of the optimization process, and various storage techniques are evaluated, including batteries, flywheels, and hybrid-engine operation.

  14. Friendship Repertoires and Care Arrangement: A Praxeological Approach.

    PubMed

    Hahmann, Julia

    2017-01-01

    Friends are important companions and serve as sources for diverse dimensions of social support, including elderly care. Rather than researching populations that have already established care arrangements including friends, the author seeks to understand relationship systems with a focus on the inner logic friendship to consequently describe and understand involved care arrangements, be it with family members or friends. To illustrate the diversity of friendship repertoires, qualitative interviews with older adult Germans are analyzed regarding cognitive concepts of friendships in contrast to familiar ties as well as social practices around relationship systems. While some repertoires successfully include chosen ties in their care arrangements, others not only focus on family, they do not wish to receive care from friends. The article's praxeological approach highlights the need to reflect habitual differences when thinking about elderly informal care arrangements. © The Author(s) 2016.

  15. Development of Life Support System Technologies for Human Lunar Missions

    NASA Technical Reports Server (NTRS)

    Barta, Daniel J.; Ewert, Michael K.

    2009-01-01

    With the Preliminary Design Review (PDR) for the Orion Crew Exploration Vehicle planned to be completed in 2009, Exploration Life Support (ELS), a technology development project under the National Aeronautics and Space Administration s (NASA) Exploration Technology Development Program, is focusing its efforts on needs for human lunar missions. The ELS Project s goal is to develop and mature a suite of Environmental Control and Life Support System (ECLSS) technologies for potential use on human spacecraft under development in support of U.S. Space Exploration Policy. ELS technology development is directed at three major vehicle projects within NASA s Constellation Program (CxP): the Orion Crew Exploration Vehicle (CEV), the Altair Lunar Lander and Lunar Surface Systems, including habitats and pressurized rovers. The ELS Project includes four technical elements: Atmosphere Revitalization Systems, Water Recovery Systems, Waste Management Systems and Habitation Engineering, and two cross cutting elements, Systems Integration, Modeling and Analysis, and Validation and Testing. This paper will provide an overview of the ELS Project, connectivity with its customers and an update to content within its technology development portfolio with focus on human lunar missions.

  16. CAE "FOCUS" for modelling and simulating electron optics systems: development and application

    NASA Astrophysics Data System (ADS)

    Trubitsyn, Andrey; Grachev, Evgeny; Gurov, Victor; Bochkov, Ilya; Bochkov, Victor

    2017-02-01

    Electron optics is a theoretical base of scientific instrument engineering. Mathematical simulation of occurring processes is a base for contemporary design of complicated devices of the electron optics. Problems of the numerical mathematical simulation are effectively solved by CAE system means. CAE "FOCUS" developed by the authors includes fast and accurate methods: boundary element method (BEM) for the electric field calculation, Runge-Kutta- Fieghlberg method for the charged particle trajectory computation controlling an accuracy of calculations, original methods for search of terms for the angular and time-of-flight focusing. CAE "FOCUS" is organized as a collection of modules each of which solves an independent (sub) task. A range of physical and analytical devices, in particular a microfocus X-ray tube of high power, has been developed using this soft.

  17. Thermodynamics of Dilute Solutions.

    ERIC Educational Resources Information Center

    Jancso, Gabor; Fenby, David V.

    1983-01-01

    Discusses principles and definitions related to the thermodynamics of dilute solutions. Topics considered include dilute solution, Gibbs-Duhem equation, reference systems (pure gases and gaseous mixtures, liquid mixtures, dilute solutions), real dilute solutions (focusing on solute and solvent), terminology, standard states, and reference systems.…

  18. End-User Imaging DISKussions.

    ERIC Educational Resources Information Center

    McConnell, Pamela Jean

    1993-01-01

    This third in a series of articles on EDIS (Electronic Document Imaging System) technology focuses on organizational issues. Highlights include computer platforms; management information systems; computer-based skills of staff; new technology and change; time factors; financial considerations; document conversion costs; the benefits of EDIS…

  19. NASA Tech Briefs, September 1995. Volume 19, No. 9

    NASA Technical Reports Server (NTRS)

    1995-01-01

    A special focus for this issue is Sensors. Topics covered include : Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Life Sciences; Mechanics; Machinery; Fabrication Technology; and Mathematics and Information Sciences. A section of Laser Tech Briefs is included.

  20. Are Integrated Portfolio Systems the Answer? An Evaluation of a Web-Based Portfolio System to Improve Preservice Teachers' Reflective Thinking Skills

    ERIC Educational Resources Information Center

    Oner, Diler; Adadan, Emine

    2016-01-01

    This study investigated the effectiveness of an integrated web-based portfolio system, namely the BOUNCE System, which primarily focuses on improving preservice teachers' reflective thinking skills. BOUNCE©, the software component of the system, was designed and developed to support a teaching practice model including a cycle of activities to be…

  1. Development of System Thinking Skills in the Context of Earth System Education

    ERIC Educational Resources Information Center

    Assaraf, Orit Ben-Zvi; Orion, Nir

    2005-01-01

    The current study deals with the development of system thinking skills at the junior high school level. The sample population included about 50 eighth-grade students from two different classes of an urban Israeli junior high school who studied an earth systems-based curriculum that focused on the hydro cycle. The study addressed the following…

  2. Personalization and Patient Involvement in Decision Support Systems: Current Trends

    PubMed Central

    Sacchi, L.; Lanzola, G.; Viani, N.

    2015-01-01

    Summary Objectives This survey aims at highlighting the latest trends (2012-2014) on the development, use, and evaluation of Information and Communication Technologies (ICT) based decision support systems (DSSs) in medicine, with a particular focus on patient-centered and personalized care. Methods We considered papers published on scientific journals, by querying PubMed and Web of Science™. Included studies focused on the implementation or evaluation of ICT-based tools used in clinical practice. A separate search was performed on computerized physician order entry systems (CPOEs), since they are increasingly embedding patient-tailored decision support. Results We found 73 papers on DSSs (53 on specific ICT tools) and 72 papers on CPOEs. Although decision support through the delivery of recommendations is frequent (28/53 papers), our review highlighted also DSSs only based on efficient information presentation (25/53). Patient participation in making decisions is still limited (9/53), and mostly focused on risk communication. The most represented medical area is cancer (12%). Policy makers are beginning to be included among stakeholders (6/73), but integration with hospital information systems is still low. Concerning knowledge representation/management issues, we identified a trend towards building inference engines on top of standard data models. Most of the tools (57%) underwent a formal assessment study, even if half of them aimed at evaluating usability and not effectiveness. Conclusions Overall, we have noticed interesting evolutions of medical DSSs to improve communication with the patient, consider the economic and organizational impact, and use standard models for knowledge representation. However, systems focusing on patient-centered care still do not seem to be available at large. PMID:26293857

  3. Electron microscope aperture system

    NASA Technical Reports Server (NTRS)

    Heinemann, K. (Inventor)

    1976-01-01

    An electron microscope including an electron source, a condenser lens having either a circular aperture for focusing a solid cone of electrons onto a specimen or an annular aperture for focusing a hollow cone of electrons onto the specimen, and an objective lens having an annular objective aperture, for focusing electrons passing through the specimen onto an image plane are described. The invention also entails a method of making the annular objective aperture using electron imaging, electrolytic deposition and ion etching techniques.

  4. 'Including health in systems responsible for urban planning': a realist policy analysis research programme.

    PubMed

    Harris, Patrick; Friel, Sharon; Wilson, Andrew

    2015-07-23

    Realist methods are increasingly being used to investigate complex public health problems. Despite the extensive evidence base clarifying the built environment as a determinant of health, there is limited knowledge about how and why land-use planning systems take on health concerns. Further, the body of research related to the wider determinants of health suffers from not using political science knowledge to understand how to influence health policy development and systems. This 4-year funded programme of research investigates how the land-use planning system in New South Wales, Australia, incorporates health and health equity at multiple levels. The programme uses multiple qualitative methods to develop up to 15 case studies of different activities of the New South Wales land-use planning system. Comparison cases from other jurisdictions will be included where possible and useful. Data collection includes publicly available documentation and purposively sampled stakeholder interviews and focus groups of up to 100 participants across the cases. The units of analysis in each case are institutional structures (rules and mandates constraining and enabling actors), actors (the stakeholders, organisations and networks involved, including health-focused agencies), and ideas (policy content, information, and framing). Data analysis will focus on and develop propositions concerning the mechanisms and conditions within and across each case leading to inclusion or non-inclusion of health. Data will be refined using additional political science and sociological theory. Qualitative comparative analysis will compare cases to develop policy-relevant propositions about the necessary and sufficient conditions needed to include health issues. Ethics has been approved by Sydney University Human Research Ethics Committee (2014/802 and 2015/178). Given the nature of this research we will incorporate stakeholders, often as collaborators, throughout. We outline our research translation strategies following best practice approaches. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  5. School-Central Office Relationships in Evidence Use: Understanding Evidence Use as a Systems Problem

    ERIC Educational Resources Information Center

    Honig, Meredith I.; Venkateswaran, Nitya

    2012-01-01

    Research on evidence use in school districts overwhelmingly focuses within schools on how school staff work with evidence including student performance data, research, and information about teaching quality. While important, this focus on schools reflects a mismatch with federal and state policies that demand not only that school staff work with…

  6. Advanced Space Transportation Concepts and Propulsion Technologies for a New Delivery Paradigm

    NASA Technical Reports Server (NTRS)

    Robinson, John W.; McCleskey, Carey M.; Rhodes, Russel E.; Lepsch, Roger A.; Henderson, Edward M.; Joyner, Claude R., III; Levack, Daniel J. H.

    2013-01-01

    This paper describes Advanced Space Transportation Concepts and Propulsion Technologies for a New Delivery Paradigm. It builds on the work of the previous paper "Approach to an Affordable and Productive Space Transportation System". The scope includes both flight and ground system elements, and focuses on their compatibility and capability to achieve a technical solution that is operationally productive and also affordable. A clear and revolutionary approach, including advanced propulsion systems (advanced LOX rich booster engine concept having independent LOX and fuel cooling systems, thrust augmentation with LOX rich boost and fuel rich operation at altitude), improved vehicle concepts (autogeneous pressurization, turbo alternator for electric power during ascent, hot gases to purge system and keep moisture out), and ground delivery systems, was examined. Previous papers by the authors and other members of the Space Propulsion Synergy Team (SPST) focused on space flight system engineering methods, along with operationally efficient propulsion system concepts and technologies. This paper continues the previous work by exploring the propulsion technology aspects in more depth and how they may enable the vehicle designs from the previous paper. Subsequent papers will explore the vehicle design, the ground support system, and the operations aspects of the new delivery paradigm in greater detail.

  7. Planning Istanbul's Public Library System.

    ERIC Educational Resources Information Center

    Dokmeci, Vedia; Korca, Perver

    1992-01-01

    Discussion of the role of public libraries in socioeconomic development focuses on an evaluation of the existing library system in Istanbul (Turkey) and proposes a plan for its balanced development with respect to population distribution and technological advances. Highlights include building design, library automation, and financial…

  8. Initial Stage Reference Search : Driver Simulators to Test Shared Controls, Limited Autonomy Vehicle Systems

    DOT National Transportation Integrated Search

    2015-09-01

    This literature review and reference scanning focuses on the use of driver simulators for semiautonomous (or shared control) vehicle systems (2012present), including related research from other modes of transportation (e.g., rail or aviation). Foc...

  9. Australian Apprenticeships. Research at a Glance.

    ERIC Educational Resources Information Center

    National Centre for Vocational Education Research, Leabrook (Australia).

    Australia's apprenticeship system was examined in 11 individual research projects that focused on various aspects of the system, including the following: milestones in its development; its changing structure; its broadening occupational base and client base; characteristics of apprentices; completion and attrition rates; outcomes from traditional…

  10. Laser cutting apparatus for nuclear core fuel subassembly

    DOEpatents

    Walch, Allan P.; Caruolo, Antonio B.

    1982-02-23

    The object of the invention is to provide a system and apparatus which employs laser cutting to disassemble a nuclear core fuel subassembly. The apparatus includes a gantry frame (C) which straddles the core fuel subassembly (14), an x-carriage (22) travelling longitudinally above the frame which carries a focus head assembly (D) having a vertically moving carriage (46) and a laterally moving carriage (52), a system of laser beam transferring and focusing mirrors carried by the x-carriage and focusing head assembly, and a shroud follower (F) and longitudinal follower (G) for following the shape of shroud (14) to maintain a beam focal point (44) fixed upon the shroud surface for accurate cutting.

  11. What constitutes an effective community pharmacy?--development of a preliminary model of organizational effectiveness through concept mapping with multiple stakeholders.

    PubMed

    Scahill, S L; Harrison, J; Carswell, P

    2010-08-01

    To develop a multi-constituent model of organizational effectiveness for community pharmacy. Using Concept Systems software, a project with 14 stakeholders included a three stage process: (i) face to face brainstorming to generate statements describing what constitutes an effective community pharmacy, followed by (ii) statement reduction and approval by participants, followed by (iii) sorting of the statements into themes with rating of each statement for importance. Primary care in a government-funded, national health care system. A multi-constituent group representing policy-makers and health care providers including; community pharmacy, professional pharmacy organizations, primary health care funders and policy-makers, general practitioners and general practice support organizations. Statement clusters included: 'has safe and effective workflows', 'contributes to the safe use of medicines', 'manages human resources and has leadership', 'has a community focus', 'is integrated within primary care', 'is a respected innovator', 'provides health promotion and preventative care', 'communicates and advocates'. These clusters fit into a quadrant model setting stakeholder focus against role development. The poles of stakeholder focus are 'internal capacity' and 'social utility'. The poles of role development are labelled 'traditional safety roles' and 'integration and innovation'. Organizational effectiveness in community pharmacy includes the internal and external focus of the organization and role development. Our preliminary model describes an effective community pharmacy and provides a platform for investigation of the factors that may influence the organizational effectiveness of individual community pharmacies now and into the future.

  12. The Carnegie Mellon/Sirsi Corporation Alliance.

    ERIC Educational Resources Information Center

    Troll, Denise A.; Depellegrin, Tracey A.; Myers, Melanie D.

    1999-01-01

    Describes the relationship between Carnegie Mellon University libraries and Sirsi Corporation, their integrated library-management system vendor. Topics include Carnegie Mellon's expertise in library automation research and development; and three primary elements of the alliance: research, including user protocols, surveys, and focus groups;…

  13. Mentoring, Networking and Supervision: Parallelogram, Vortex, or Merging Point?

    ERIC Educational Resources Information Center

    Hernandez, Mary N.

    1994-01-01

    Discussion of recruiting and hiring minorities in academic libraries focuses on steps needed for the retention of these minorities. Highlights include literature search strategies; mentoring systems; networking within and outside the organization; and supervision, including immediate feedback. (Contains 20 references.) (LRW)

  14. Human Systems Integration at NASA Ames Research Center

    NASA Technical Reports Server (NTRS)

    McCandless, Jeffrey

    2017-01-01

    The Human Systems Integration Division focuses on the design and operations of complex aerospace systems through analysis, experimentation and modeling. With over a dozen labs and over 120 people, the division conducts research to improve safety, efficiency and mission success. Areas of investigation include applied vision research which will be discussed during this seminar.

  15. Sleep, Off-Line Processing, and Vocal Learning

    ERIC Educational Resources Information Center

    Margoliash, Daniel; Schmidt, Marc F.

    2010-01-01

    The study of song learning and the neural song system has provided an important comparative model system for the study of speech and language acquisition. We describe some recent advances in the bird song system, focusing on the role of off-line processing including sleep in processing sensory information and in guiding developmental song…

  16. "Winsight"™ Assessment System: Preliminary Theory of Action. Research Report. ETS RR-17-26

    ERIC Educational Resources Information Center

    Wylie, E. Caroline

    2017-01-01

    The "Winsight"™Assessment System integrates summative, interim (including both benchmark assessments and testlets), and formative assessment components initially focused on mathematics and English language arts (ELA) in Grades 3-8 and high school.This report provides a preliminary theory of action for the Winsight Assessment System. A…

  17. Consumer response to a report card comparing healthcare systems.

    PubMed

    Braun, Barbara L; Kind, Elizabeth A; Fowles, Jinnet B; Suarez, Walter G

    2002-06-01

    Report cards to date have focused on quality of care in health plans rather than within healthcare delivery systems. The purpose of this study was to evaluate consumer response to the first healthcare system-level report card. Qualitative assessment of consumer response. We conducted 5 focus groups of community members to evaluate consumer response to the report card; 2 included community club members, 3 included community-dwelling retired persons. Discussions were audiotaped and transcribed; comments were categorized by topic area from the script, and common themes identified. Focus group participants, in general, were unaware of the current emphasis on medical quality improvement initiatives. However, they believed that the opinion that the descriptive clinic information and patient survey data contained in the report card would be most useful mainly for choosing a healthcare system if they were dissatisfied with current medical care, if their healthcare options changed, or if they were in poor health. Personal experience was considered a more trustworthy measure of healthcare quality than were patient survey results. Trustworthiness was perceived to be higher if the report card sponsor was not affiliated with the healthcare systems being evaluated. Participants also believed care system administrators should use the data to enact positive clinic-level and physician-level changes. Healthcare consumers appreciated the attention to patient experiences and supported healthcare quality improvement initiatives. Report cards were considered important for choosing a healthcare system in certain circumstances and for guiding quality improvement efforts at all levels.

  18. Introduction

    NASA Astrophysics Data System (ADS)

    Zhao, Ben; Garbacki, Paweł; Gkantsidis, Christos; Iamnitchi, Adriana; Voulgaris, Spyros

    After a decade of intensive investigation, peer-to-peer computing has established itself as an accepted research eld in the general area of distributed systems. Peer-to- peer computing can be seen as the democratization of computing over throwing traditional hierarchical designs favored in client-server systems largely brought about by last-mile network improvements which have made individual PCs rst-class citizens in the network community. Much of the early focus in peer-to-peer systems was on best-effort le sharing applications. In recent years, however, research has focused on peer-to-peer systems that provide operational properties and functionality similar to those shown by more traditional distributed systems. These properties include stronger consistency, reliability, and security guarantees suitable to supporting traditional applications such as databases.

  19. New Focal Plane Array Controller for the Instruments of the Subaru Telescope

    NASA Astrophysics Data System (ADS)

    Nakaya, Hidehiko; Komiyama, Yutaka; Miyazaki, Satoshi; Yamashita, Takuya; Yagi, Masafumi; Sekiguchi, Maki

    2006-03-01

    We have developed a next-generation data acquisition system, MESSIA5 (Modularized Extensible System for Image Acquisition), which comprises the digital part of a focal plane array controller. The new data acquisition system was constructed based on a 64 bit, 66 MHz PCI (peripheral component interconnect) bus architecture and runs on an x86 CPU computer with (non-real-time) Linux. The system, including the CPU board, is placed at the telescope focus, and standard gigabit Ethernet is adopted for the data transfer, as opposed to a dedicated fiber link. During the summer of 2002, we installed the new system for the first time on the Subaru prime-focus camera Suprime-Cam and successfully improved the observing performance.

  20. Propulsion System Choices and Their Implications

    NASA Technical Reports Server (NTRS)

    Joyner, Claude R., II; Levack, Daniel J. H.; Rhodes, Russell, E.; Robinson, John W.

    2010-01-01

    In defining a space vehicle architecture, the propulsion system and related subsystem choices will have a major influence on achieving the goals and objectives desired. There are many alternatives and the choices made must produce a system that meets the performance requirements, but at the same time also provide the greatest opportunity of reaching all of the required objectives. Recognizing the above, the SPST Functional Requirements subteam has drawn on the knowledge, expertise, and experience of its members, to develop insight that wiIJ effectively aid the architectural concept developer in making the appropriate choices consistent with the architecture goals. This data not only identifies many selected choices, but also, more importantly, presents the collective assessment of this subteam on the "pros" and the "cons" of these choices. The propulsion system choices with their pros and cons are presented in five major groups. A. System Integration Approach. Focused on the requirement for safety, reliability, dependability, maintainability, and low cost. B. Non-Chemical Propulsion. Focused on choice of propulsion type. C. Chemical Propulsion. Focused on propellant choice implications. D. Functional Integration. Focused on the degree of integration of the many propulsive and closely associated functions, and on the choice of the engine combustion power cycle. E. Thermal Management. Focused on propellant tank insulation and integration. Each of these groups is further broken down into subgroups, and at that level the consensus pros and cons are presented. The intended use of this paper is to provide a resource of focused material for architectural concept developers to use in designing new advanced systems including college design classes. It is also a possible source of input material for developing a model for designing and analyzing advanced concepts to help identify focused technology needs and their priorities.

  1. Elastin-Like Recombinamers As Smart Drug Delivery Systems.

    PubMed

    Arias, F Javier; Santos, Mercedes; Ibanez-Fonseca, Arturo; Pina, Maria Jesus; Serrano, Sofía

    2018-02-19

    Drug delivery systems that are able to control the release of bioactive molecules and designed to carry drugs to target sites are of particular interest for tissue therapy. Moreover, systems comprising materials that can respond to environmental stimuli and promote self-assembly and higher order supramolecular organization are especially useful in the biomedical field. Objetive: This review focuses on biomaterials suitable for this purpose and that include elastin-like recombinamers (ELRs), a class of proteinaceous polymers bioinspired by natural elastin, designed using recombinant technologies. The self-assembly and thermoresponsive behaviour of these systems, along with their biodegradability, biocompatibility and well-defined composition as a result of their tailormade design, make them particularly attractive for controlled drug delivery. ELR-based delivery systems that allow targeted delivery are reviewed, especially ELR-drug recombinant fusion constructs, ELR-drug systems chemically bioconjugated in their monomeric and soluble forms, and drug encapsulation by nanoparticle-forming ELRs. Subsequently, the review focuses on those drug carriers in which smart release is triggered by pH or temperature with a particular focus on cancer treatments. Systems for controlled drug release based on depots and hydrogels that act as both a support and reservoir in which drugs can be stored will be described, and their applications in drug delivery discussed. Finally, smart drug-delivery systems not based on ELRs, including those comprising proteins, synthetic polymers and non-polymeric systems, will also be briefly discussed. Several different constructions based on ELRs are potential candidates for controlled drug delivery to be applied in advanced biomedical treatments. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  2. Micro- and nanofabrication methods in nanotechnological medical and pharmaceutical devices

    PubMed Central

    Betancourt, Tania; Brannon-Peppas, Lisa

    2006-01-01

    Micro- and nanofabrication techniques have revolutionized the pharmaceutical and medical fields as they offer the possibility for highly reproducible mass-fabrication of systems with complex geometries and functionalities, including novel drug delivery systems and bionsensors. The principal micro- and nanofabrication techniques are described, including photolithography, soft lithography, film deposition, etching, bonding, molecular self assembly, electrically induced nanopatterning, rapid prototyping, and electron, X-ray, colloidal monolayer, and focused ion beam lithography. Application of these techniques for the fabrication of drug delivery and biosensing systems including injectable, implantable, transdermal, and mucoadhesive devices is described. PMID:17722281

  3. BeSocratic: An Intelligent Tutoring System for the Recognition, Evaluation, and Analysis of Free-Form Student Input

    ERIC Educational Resources Information Center

    Bryfczynski, Samuel Paul

    2012-01-01

    This dissertation describes a novel intelligent tutoring system, BeSocratic, which aims to help fill the gap between simple multiple-choice systems and free-response systems. BeSocratic focuses on targeting questions that are free-form in nature yet defined to the point which allows for automatic evaluation and analysis. The system includes a set…

  4. Biodegradable Scaffolds for Bone Regeneration Combined with Drug-Delivery Systems in Osteomyelitis Therapy

    PubMed Central

    Dorati, Rossella; DeTrizio, Antonella; Modena, Tiziana; Conti, Bice; Benazzo, Francesco; Gastaldi, Giulia; Genta, Ida

    2017-01-01

    A great deal of research is ongoing in the area of tissue engineering (TE) for bone regeneration. A possible improvement in restoring damaged tissues involves the loading of drugs such as proteins, genes, growth factors, antibiotics, and anti-inflammatory drugs into scaffolds for tissue regeneration. This mini-review is focused on the combination of the local delivery of antibiotic agents with bone regenerative therapy for the treatment of a severe bone infection such as osteomyelitis. The review includes a brief explanation of scaffolds for bone regeneration including scaffolds characteristics and types, a focus on severe bone infections (especially osteomyelitis and its treatment), and a literature review of local antibiotic delivery by the combination of scaffolds and drug-delivery systems. Some examples related to published studies on gentamicin sulfate-loaded drug-delivery systems combined with scaffolds are discussed, and future perspectives are highlighted. PMID:29231857

  5. Overview of Stirling Technology Research at NASA Glenn Research Center

    NASA Technical Reports Server (NTRS)

    Wilson, Scott D.; Schifer, Nicholas A.; Williams, Zachary D.; Metscher, Jonathan F.

    2016-01-01

    Stirling Radioisotope Power Systems (RPSs) are under development to provide power on future space science missions where robotic spacecraft will orbit, fly by, land, or rove using less than a quarter of the plutonium the currently available RPS uses to produce about the same power. NASA Glenn Research Center's newly formulated Stirling Cycle Technology Development Project (SCTDP) continues development of Stirling-based systems and subsystems, which include a flight-like generator and related housing assembly, controller, and convertors. The project also develops less mature technologies under Stirling Technology Research, with a focus on demonstration in representative environments to increase the technology readiness level (TRL). Matured technologies are evaluated for selection in future generator designs. Stirling Technology Research tasks focus on a wide variety of objectives, including increasing temperature capability to enable new environments, reducing generator mass and/or size, improving reliability and system fault tolerance, and developing alternative designs. The task objectives and status are summarized.

  6. Overview of Stirling Technology Research at NASA Glenn Research Center

    NASA Technical Reports Server (NTRS)

    Wilson, Scott D.; Schifer, Nicholas A.; Williams, Zachary D.; Metscher, Jonathan F.

    2015-01-01

    Stirling Radioisotope Power Systems (RPS) are under development to provide power on future space science missions where robotic spacecraft will orbit, flyby, land or rove using less than a quarter of the plutonium the currently available RPS uses to produce about the same power. Glenn Research Center's (GRC's) newly formulated Stirling Cycle Technology Development Project (SCTDP) continues development of Stirling-based systems and subsystems, which include a flight-like generator and related housing assembly, controller, and convertors. The project also develops less mature technologies under Stirling Technology Research, with a focus on demonstration in representative environments to increase the technology readiness level (TRL). Matured technologies are evaluated for selection in future generator designs. Stirling Technology Research tasks focus on a wide variety of objectives, including increasing temperature capability to enable new environments, reducing generator mass and/or size, improving reliability or system fault tolerance, and developing alternative designs. The task objectives and status are summarized.

  7. Space Station Human Factors Research Review. Volume 1: EVA Research and Development

    NASA Technical Reports Server (NTRS)

    Cohen, Marc M. (Editor); Vykukal, H. C. (Editor)

    1988-01-01

    An overview is presented of extravehicular activity (EVA) research and development activities at Ames. The majority of the program was devoted to presentations by the three contractors working in parallel on the EVA System Phase A Study, focusing on Implications for Man-Systems Design. Overhead visuals are included for a mission results summary, space station EVA requirements and interface accommodations summary, human productivity study cross-task coordination, and advanced EVAS Phase A study implications for man-systems design. Articles are also included on subsea approach to work systems development and advanced EVA system design requirements.

  8. Development of a Space-Rated Proton Exchange Membrane Fuel Cell

    NASA Technical Reports Server (NTRS)

    Hoffman, William C., III; Vasquez, Arturo; Lazaroff, Scott M.; Downey, Michael G.

    1999-01-01

    Power systems for human spacecraft have historically included fuel cells due to the superior energy density they offer over battery systems depending on mission length and power consumption. As space exploration focuses on the evolution of reusable spacecraft and also considers planetary exploration power system requirements, fuel cells continue to be a factor in the potential system solutions.

  9. Control, Filtering and Prediction for Phased Arrays in Directed Energy Systems

    DTIC Science & Technology

    2016-04-30

    adaptive optics. 15. SUBJECT TERMS control, filtering, prediction, system identification, adaptive optics, laser beam pointing, target tracking, phase... laser beam control; furthermore, wavefront sensors are plagued by the difficulty of maintaining the required alignment and focusing in dynamic mission...developed new methods for filtering, prediction and system identification in adaptive optics for high energy laser systems including phased arrays. The

  10. Integro-differential equation analysis and radioisotope imaging systems. Research proposal. [Testing of radioisotope imaging system in phantoms

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hart, H.

    1976-03-09

    Design modifications of a five-probe focusing collimator coincidence radioisotope scanning system are described. Clinical applications of the system were tested in phantoms using radioisotopes with short biological half-lives, including /sup 75/Se, /sup 192/Ir, /sup 43/K, /sup 130/I, and /sup 82/Br. Data processing methods are also described. (CH)

  11. The proposal of recommendations for the operation of vacuum sewerage

    NASA Astrophysics Data System (ADS)

    Mazák, J.; Dvorský, T.; Václavík, V.; Zajac, R.; Hluštík, P.

    2017-10-01

    This article deals with a comparison of vacuum sewerage system and gravity based sewerage system. It also includes the results of the comparison of both of these systems from various cities, and there are measures suggested on the basis of the findings focused on increasing the efficiency and reducing the operational costs of the selected vacuum sewerage system.

  12. Issues in NASA Program and Project Management: Focus on Project Planning and Scheduling

    NASA Technical Reports Server (NTRS)

    Hoffman, Edward J. (Editor); Lawbaugh, William M. (Editor)

    1997-01-01

    Topics addressed include: Planning and scheduling training for working project teams at NASA, overview of project planning and scheduling workshops, project planning at NASA, new approaches to systems engineering, software reliability assessment, and software reuse in wind tunnel control systems.

  13. National Automotive Sampling System (NASS) Crashworthiness Data System : analytical user's manual 2007 file

    DOT National Transportation Integrated Search

    2008-01-01

    Comparing the 1988-2007 files with files from years prior to 1988 is not recommended. The : principal attributes of the NASS CDS 1988-2007 files include: focusing on crashes involving : automobiles and automobile derivatives, light trucks and vans wi...

  14. ENERGY AND OUR ENVIRONMENT: A SYSTEMS AND LIFE CYCLE PERSPECTIVE

    EPA Science Inventory

    This is a presentation to the North Carolina BREATE Conference on March 28, 2017. This presentation provides an overview of energy modeling capabilities in ORD, and includes examples related to scenario development, water-energy nexus, bioenergy, etc. The focus is on system ap...

  15. Design and Implementation of a Tool for Teaching Programming.

    ERIC Educational Resources Information Center

    Goktepe, Mesut; And Others

    1989-01-01

    Discussion of the use of computers in education focuses on a graphics-based system for teaching the Pascal programing language for problem solving. Topics discussed include user interface; notification based systems; communication processes; object oriented programing; workstations; graphics architecture; and flowcharts. (18 references) (LRW)

  16. Technical Training: A Systematic Approach.

    ERIC Educational Resources Information Center

    Gammuto, John J.

    1980-01-01

    To employ scarce personnel and money to best advantage, company management must diagnose critical training needs and assign them priorities. A systems approach is recommended, which gives focus to training design while accommodating most organization training goals. Included are suggestions for system design, facility management, and cost…

  17. Are Microsoft's Animated Interface Agents Helpful?

    ERIC Educational Resources Information Center

    Head, Allison J.

    1998-01-01

    Discusses interface agents and online help systems, focusing on Microsoft's animated office assistants. Highlights include intermediaries such as librarians in off-line reference problems; user complaints about online help systems; navigation problems; evaluation of the online office assistants; and categories of user queries to online help…

  18. Knowledge and motivation: two elements of health literacy that remain low with regard to nurse practitioners in Australia.

    PubMed

    Cashin, Andrew; Heartfield, Marie; Cox, Darlene; Dunn, Sandra; Stasa, Helen

    2015-09-01

    This paper presents analysis of consumer focus groups that were undertaken as a part of the project to develop the now current Nursing and Midwifery Board of Australia's Nurse Practitioner Standards for Practice. Six focus groups were conducted with consumers around Australia, including urban and remote areas. One purpose for these groups was to explore what was known of nurse practitioners and whether consumers could articulate the difference between the regulated titles of enrolled nurse, registered nurse and nurse practitioner. Consumers' knowledge of nurses' roles in the Australian primary healthcare system, and hence system literacy (particularly in terms of navigating the system), was low. Of perhaps greatest importance is the fact that those consumers with low health systems literacy also exhibited a low level of motivation to seek new knowledge. Many consumers relied on the medical profession to direct care. The low levels of health literacy raise questions of how to meaningfully include health consumers in innovative health-related policy work.

  19. Small Bodies, Big Discoveries: NASA's Small Bodies Education Program

    NASA Astrophysics Data System (ADS)

    Mayo, L.; Erickson, K. J.

    2014-12-01

    2014 is turning out to be a watershed year for celestial events involving the solar system's unsung heroes, small bodies. This includes the close flyby of comet C/2013 A1 / Siding Spring with Mars in October and the historic Rosetta mission with its Philae lander to comet 67P/Churyumov-Gerasimenko. Beyond 2014, the much anticipated 2015 Pluto flyby by New Horizons and the February Dawn Mission arrival at Ceres will take center stage. To deliver the excitement and wonder of our solar system's small bodies to worldwide audiences, NASA's JPL and GSFC education teams in partnership with NASA EDGE will reach out to the public through multiple venues including broadcast media, social media, science and math focused educational activities, observing challenges, interactive visualization tools like "Eyes on the Solar System" and more. This talk will highlight NASA's focused education effort to engage the public in small bodies mission science and the role these objects play in our understanding of the formation and evolution of the solar system.

  20. Uncorrelated Encounter Model of the National Airspace System, Version 2.0

    DTIC Science & Technology

    2013-08-19

    can exist to certify avoidance systems for operational use. Evaluations typically include flight tests, operational impact studies, and simulation of...appropriate for large-scale air traffic impact studies— for example, examination of sector loading or conflict rates. The focus here includes two types of...between two IFR aircraft in oceanic airspace. The reason for this is that one cannot observe encounters of sufficient fidelity in the available data

  1. Cereal transformation through particle bombardment

    NASA Technical Reports Server (NTRS)

    Casas, A. M.; Kononowicz, A. K.; Bressan, R. A.; Hasegawa, P. M.; Mitchell, C. A. (Principal Investigator)

    1995-01-01

    The review focuses on experiments that lead to stable transformation in cereals using microprojectile bombardment. The discussion of biological factors that affect transformation examines target tissues and vector systems for gene transfer. The vector systems include reporter genes, selectable markers, genes of agronomic interest, and vector constructions. Other topics include physical parameters that affect DNA delivery, selection of stably transformed cells and plant regeneration, and analysis of gene expression and transmission to the progeny.

  2. Collaborative mental health services in primary care systems in Latin America: contextualized evaluation needs and opportunities.

    PubMed

    Sapag, Jaime C; Rush, Brian; Ferris, Lorraine E

    2016-02-01

    This study examined Latin American evaluation needs regarding the development of a collaborative mental health care (CMHC) evaluation framework as seen by local key health-care leaders and professionals. Potential implementation challenges and opportunities were also identified. This multisite research study used an embedded mixed methods approach in three public health networks in Mexico, Nicaragua and Chile. Local stakeholders participated: decision-makers in key informant interviews, front-line clinicians in focus groups and other stakeholders through a survey. The analysis was conducted within site and then across sites. A total of 22 semi-structured interviews, three focus groups and 27 questionnaires (52% response rate) were conducted. Participants recognized a strong need to evaluate different areas of CMHC in Latin America, including access, types and quality of services, human resources and outcomes related to mental disorders, including addiction. A priority was to evaluate collaboration within the health system, including the referral system. Issues of feasibility, including the weaknesses of information systems, were also identified. Local stakeholders strongly supported the development of a comprehensive evaluation framework for CMHC in Latin America and cited several dimensions and contextual factors critical for inclusion. Implementation must allow flexibility and adaptation to the local context. © 2015 John Wiley & Sons Ltd.

  3. Assessing the ACGME Competencies in Psychiatry Training Programs

    ERIC Educational Resources Information Center

    Swick, Susan; Hall, Sarah; Beresin, Eugene

    2006-01-01

    In 2000, the Accreditation Council of Graduate Medical Education (ACGME) laid out a definition of competence that included six specific areas of focus: patient care (including clinical reasoning), medical knowledge, practice-based learning and improvement, interpersonal and communication skills, professionalism, and systems-based practice. The…

  4. A Survey in Indexing and Searching XML Documents.

    ERIC Educational Resources Information Center

    Luk, Robert W. P.; Leong, H. V.; Dillon, Tharam S.; Chan, Alvin T. S.; Croft, W. Bruce; Allan, James

    2002-01-01

    Discussion of XML focuses on indexing techniques for XML documents, grouping them into flat-file, semistructured, and structured indexing paradigms. Highlights include searching techniques, including full text search and multistage search; search result presentations; database and information retrieval system integration; XML query languages; and…

  5. Involvement of older people in the development of fall detection systems: a scoping review.

    PubMed

    Thilo, Friederike J S; Hürlimann, Barbara; Hahn, Sabine; Bilger, Selina; Schols, Jos M G A; Halfens, Ruud J G

    2016-02-11

    The involvement of users is recommended in the development of health related technologies, in order to address their needs and preferences and to improve the daily usage of these technologies. The objective of this literature review was to identify the nature and extent of research involving older people in the development of fall detection systems. A scoping review according to the framework of Arksey and O'Malley was carried out. A key term search was employed in eight relevant databases. Included articles were summarized using a predetermined charting form and subsequently thematically analysed. A total of 53 articles was included. In 49 of the 53 articles, older people were involved in the design and/or testing stages, and in 4 of 53 articles, they were involved in the conceptual or market deployment stages. In 38 of the 53 articles, the main focus of the involvement of older people was technical aspects. In 15 of the 53 articles, the perspectives of the elderly related to the fall detection system under development were determined using focus groups, single interviews or questionnaires. Until presently, involvement of older people in the development of fall detection systems has focused mainly on technical aspects. Little attention has been given to the specific needs and views of older people in the context of fall detection system development and usage.

  6. Ion beam accelerator system

    NASA Technical Reports Server (NTRS)

    Aston, G. (Inventor)

    1981-01-01

    A system is described that combines geometrical and electrostatic focusing to provide high ion extraction efficiency and good focusing of an accelerated ion beam. The apparatus includes a pair of curved extraction grids with multiple pairs of aligned holes positioned to direct a group of beamlets along converging paths. The extraction grids are closely spaced and maintained at a moderate potential to efficiently extract beamlets of ions and allow them to combine into a single beam. An accelerator electrode device downstream from the extraction grids is at a much lower potential than the grids to accelerate the combined beam. The application of the system to ion implantation is mentioned.

  7. Tree physiology research in a changing world.

    PubMed

    Kaufmann, Merrill R.; Linder, Sune

    1996-01-01

    Changes in issues and advances in methodology have contributed to substantial progress in tree physiology research during the last several decades. Current research focuses on process interactions in complex systems and the integration of processes across multiple spatial and temporal scales. An increasingly important challenge for future research is assuring sustainability of production systems and forested ecosystems in the face of increased demands for natural resources and human disturbance of forests. Meeting this challenge requires significant shifts in research approach, including the study of limitations of productivity that may accompany achievement of system sustainability, and a focus on the biological capabilities of complex land bases altered by human activity.

  8. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Maloney, J.; Kiepper, A.F.; Simonetta, R.J.

    The volume examines monitoring and reporting procedures applicable to performance and productivity. The managers of three transit systems of varying sizes discuss how productivity has been increased within their systems. The Pittsburgh discussion reviews a variety of capital projects and management improvement initiatives undertaken by Port Authority Transit, including development of maintenance manuals and an absenteeism reduction project. The Houston discussion describes how the property used a management study to identify needed organizational change and restructuring. The Ann Arbor discussion focuses on a set of service standards and performance indicators adopted to focus the management improvement process.

  9. Ion implantation for deterministic single atom devices

    NASA Astrophysics Data System (ADS)

    Pacheco, J. L.; Singh, M.; Perry, D. L.; Wendt, J. R.; Ten Eyck, G.; Manginell, R. P.; Pluym, T.; Luhman, D. R.; Lilly, M. P.; Carroll, M. S.; Bielejec, E.

    2017-12-01

    We demonstrate a capability of deterministic doping at the single atom level using a combination of direct write focused ion beam and solid-state ion detectors. The focused ion beam system can position a single ion to within 35 nm of a targeted location and the detection system is sensitive to single low energy heavy ions. This platform can be used to deterministically fabricate single atom devices in materials where the nanostructure and ion detectors can be integrated, including donor-based qubits in Si and color centers in diamond.

  10. Remote Sensing Information Sciences Research Group, Santa Barbara Information Sciences Research Group, year 3

    NASA Technical Reports Server (NTRS)

    Estes, J. E.; Smith, T.; Star, J. L.

    1986-01-01

    Research continues to focus on improving the type, quantity, and quality of information which can be derived from remotely sensed data. The focus is on remote sensing and application for the Earth Observing System (Eos) and Space Station, including associated polar and co-orbiting platforms. The remote sensing research activities are being expanded, integrated, and extended into the areas of global science, georeferenced information systems, machine assissted information extraction from image data, and artificial intelligence. The accomplishments in these areas are examined.

  11. Remote Sensing Information Sciences Research Group: Santa Barbara Information Sciences Research Group, year 4

    NASA Technical Reports Server (NTRS)

    Estes, John E.; Smith, Terence; Star, Jeffrey L.

    1987-01-01

    Information Sciences Research Group (ISRG) research continues to focus on improving the type, quantity, and quality of information which can be derived from remotely sensed data. Particular focus in on the needs of the remote sensing research and application science community which will be served by the Earth Observing System (EOS) and Space Station, including associated polar and co-orbiting platforms. The areas of georeferenced information systems, machine assisted information extraction from image data, artificial intelligence and both natural and cultural vegetation analysis and modeling research will be expanded.

  12. Ion implantation for deterministic single atom devices

    DOE PAGES

    Pacheco, J. L.; Singh, M.; Perry, D. L.; ...

    2017-12-04

    Here, we demonstrate a capability of deterministic doping at the single atom level using a combination of direct write focused ion beam and solid-state ion detectors. The focused ion beam system can position a single ion to within 35 nm of a targeted location and the detection system is sensitive to single low energy heavy ions. This platform can be used to deterministically fabricate single atom devices in materials where the nanostructure and ion detectors can be integrated, including donor-based qubits in Si and color centers in diamond.

  13. Adaptive Interface Approach Using a Real Time Biocybernetic System: Control of Hazardous Awareness

    NASA Technical Reports Server (NTRS)

    Ray, William J.

    2002-01-01

    The focus of this current grant was to continue our work which focused on the manner in which psychophysiological markers can be used to index hazardous states of awareness and to explore the feasibility of developing on-line systems that utilize real time feedback to modify on-going behavioral processes. In this work we have incorporated a multifaceted approach which includes psychophysiological, subjective, and performance based measures. We have considered this from both an internal and external perspective as reflected in work from a variety of labs.

  14. Measure Guideline. Steam System Balancing and Tuning for Multifamily Residential Buildings

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Choi, Jayne; Ludwig, Peter; Brand, Larry

    2013-04-01

    This guideline provides building owners, professionals involved in multifamily audits, and contractors insights for improving the balance and tuning of steam systems. It provides readers an overview of one-pipe steam heating systems, guidelines for evaluating steam systems, typical costs and savings, and guidelines for ensuring quality installations. It also directs readers to additional resources for details not included here. Measures for balancing a distribution system that are covered include replacing main line vents and upgrading radiator vents. Also included is a discussion on upgrading boiler controls and the importance of tuning the settings on new or existing boiler controls. Themore » guideline focuses on one-pipe steam systems, though many of the assessment methods can be generalized to two-pipe steam systems.« less

  15. Measurement of Sexual Health in the U.S.: An Inventory of Nationally Representative Surveys and Surveillance Systems

    PubMed Central

    Ivankovich, Megan B.; Leichliter, Jami S.; Douglas, John M.

    2013-01-01

    Objectives To identify opportunities within nationally representative surveys and surveillance systems to measure indicators of sexual health, we reviewed and inventoried existing data systems that include variables relevant to sexual health. Methods We searched for U.S. nationally representative surveys and surveillance systems that provided individual-level sexual health data. We assessed the methods of each data system and catalogued them by their measurement of the following domains of sexual health: knowledge, communication, attitudes, service access and utilization, sexual behaviors, relationships, and adverse health outcomes. Results We identified 18 U.S.-focused, nationally representative data systems: six assessing the general population, seven focused on special populations, and five addressing health outcomes. While these data systems provide a rich repository of information from which to assess national measures of sexual health, they present several limitations. Most importantly, apart from data on service utilization, routinely gathered, national data are currently focused primarily on negative aspects of sexual health (e.g., risk behaviors and adverse health outcomes) rather than more positive attributes (e.g., healthy communication and attitudes, and relationship quality). Conclusion Nationally representative data systems provide opportunities to measure a broad array of domains of sexual health. However, current measurement gaps indicate the need to modify existing surveys, where feasible and appropriate, and develop new tools to include additional indicators that address positive domains of sexual health of the U.S. population across the life span. Such data can inform the development of effective policy actions, services, prevention programs, and resource allocation to advance sexual health. PMID:23450886

  16. Pediatric post-marketing safety systems in North America: assessment of the current status.

    PubMed

    McMahon, Ann W; Wharton, Gerold T; Bonnel, Renan; DeCelle, Mary; Swank, Kimberley; Testoni, Daniela; Cope, Judith U; Smith, Phillip Brian; Wu, Eileen; Murphy, Mary Dianne

    2015-08-01

    It is critical to have pediatric post-marketing safety systems that contain enough clinical and epidemiological detail to draw regulatory, public health, and clinical conclusions. The pediatric safety surveillance workshop (PSSW), coordinated by the Food and Drug Administration (FDA), identified these pediatric systems as of 2010. This manuscript aims to update the information from the PSSW and look critically at the systems currently in use. We reviewed North American pediatric post-marketing safety systems such as databases, networks, and research consortiums found in peer-reviewed journals and other online sources. We detail clinical examples from three systems that FDA used to assess pediatric medical product safety. Of the 59 systems reviewed for pediatric content, only nine were pediatric-focused and met the inclusion criteria. Brief descriptions are provided for these nine. The strengths and weaknesses of three systems (two of the nine pediatric-focused and one including both children and adults) are illustrated with clinical examples. Systems reviewed in this manuscript have strengths such as clinical detail, a large enough sample size to capture rare adverse events, and/or a patient denominator internal to the database. Few systems include all of these attributes. Pediatric drug safety would be better informed by utilizing multiple systems to take advantage of their individual characteristics. Copyright © 2015 John Wiley & Sons, Ltd.

  17. Life Support and Habitation Systems: Crew Support and Protection for Human Exploration Missions Beyond Low Earth Orbit

    NASA Technical Reports Server (NTRS)

    Barta, Daniel J.; McQuillan, Jeffrey

    2011-01-01

    The National Aeronautics and Space Administration (NASA) has recently expanded its mission set for possible future human exploration missions. With multiple options there is interest in identifying technology needs across these missions to focus technology investments. In addition to the Moon and other destinations in cis-lunar space, other destinations including Near Earth Objects and Mars have been added for consideration. Recently, technology programs and projects have been re-organizing to better meet the Agency s strategic goals and address needs across these potential future missions. Life Support and Habitation Systems (LSHS) is one of 10 Foundational Domains as part of the National Aeronautics and Space Administration s Exploration Technology Development Program. The chief goal of LSHS is to develop and mature advanced technologies to sustain human life on missions beyond Low Earth Orbit (LEO) to increase reliability, reduce dependency on resupply and increase vehicle self-sufficiency. For long duration exploration missions, further closure of life support systems is of interest. Focus includes key technologies for atmosphere revitalization, water recovery, waste management, thermal control and crew accommodations. Other areas of focus include technologies for radiation protection, environmental monitoring and fire protection. The aim is to recover additional consumable mass, reduce requirements for power, volume, heat rejection, crew involvement, and meet exploration vehicle requirements. This paper provides a brief description of the LSHS Foundational Domain as defined for fiscal year 2011.

  18. Continental United States Military Housing Inspections Southeast

    DTIC Science & Technology

    2015-09-24

    and safety, including focus on mold, asbestos , radon, lead-based paint, drinking water quality, and pest management. We conducted this inspection in...electrical system safety inspections. In addition, we inspected to EPA standards governing safe drinking water and toxic substances, radon, asbestos , and...inspections focused on mold, asbestos , radon, lead-based paint, drinking water quality, and pest management. We evaluated the associated plans and

  19. City and County Solar PV Training Program, Module 3: Detailed Site Evaluation, Project Validation, and Permitting

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Day, Megan H; Lisell, Lars J

    This is the third of five training modules recorded for the City and County Solar PV Training Program. The program is focused on training local government staff in the PV procurement process. This module focuses on siting and permitting for both rooftop and larger, ground-mounted systems rand includes a link to a video.

  20. A Review and Critique of Rural Development Research in the Land-Grant System Since 1970--with Focus upon the South. SRDC Series 65.

    ERIC Educational Resources Information Center

    Beaulieu, Lionel J.; Voth, Donald E.

    An overview of rural development research in the United States Department of Agriculture's land grant environment focuses on southern 1862 and 1890 institutions. Although important to agricultural experiment stations, rural development research has received limited funding. A heterogeneous research program including human resources development,…

  1. Radiation damage and waste management options for the SOMBRERO final focus system and neutron dumps

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Latkowski, J F; Meier, W R; Reyes, S

    1999-08-09

    Previous studies of the safety and environmental aspects of the SOMBRERO inertial fusion energy (IFE) power plant design did not completely address the issues associated with the final focus system. While past work calculated neutron fluences for a grazing incidence metal mirror (GIMM) and a final focus mirror, scattering off of the final optical component was not included, and thus, fluences in the final focus mirror were significantly underestimated. In addition, past work did not consider neutron-induced gamma-rays. Finally, power plant lifetime waste volumes may have been underestimated as neutron activation of the neutron dumps and building structure were notmore » addressed. In the present work, a modified version of the SOMBRERO target building is presented where a significantly larger open solid-angle fraction (5%) is used to enhance beam smoothing of a diode-pumped solid-state laser (DPSSL). The GIMMs are replaced with transmissive fused silica wedges and have been included in three -dimensional neutron and photon transport calculations. This work shows that a power plant with a large open solid-angle fraction, needed for beam smoothing with a DPSSL, is acceptable from tritium breeding, and neutron activation points-of-view.« less

  2. Xiangkun Li | NREL

    Science.gov Websites

    Xiangkun Li Xiangkun Li Engineer - Energy Optimization Modeling Xiangkun.Li@nrel.gov | 303-275-4372 focus areas include renewable energy integration, energy systems optimization, and power flow modeling

  3. Finding Important Terms for Patients in Their Electronic Health Records: A Learning-to-Rank Approach Using Expert Annotations.

    PubMed

    Chen, Jinying; Zheng, Jiaping; Yu, Hong

    2016-11-30

    Many health organizations allow patients to access their own electronic health record (EHR) notes through online patient portals as a way to enhance patient-centered care. However, EHR notes are typically long and contain abundant medical jargon that can be difficult for patients to understand. In addition, many medical terms in patients' notes are not directly related to their health care needs. One way to help patients better comprehend their own notes is to reduce information overload and help them focus on medical terms that matter most to them. Interventions can then be developed by giving them targeted education to improve their EHR comprehension and the quality of care. We aimed to develop a supervised natural language processing (NLP) system called Finding impOrtant medical Concepts most Useful to patientS (FOCUS) that automatically identifies and ranks medical terms in EHR notes based on their importance to the patients. First, we built an expert-annotated corpus. For each EHR note, 2 physicians independently identified medical terms important to the patient. Using the physicians' agreement as the gold standard, we developed and evaluated FOCUS. FOCUS first identifies candidate terms from each EHR note using MetaMap and then ranks the terms using a support vector machine-based learn-to-rank algorithm. We explored rich learning features, including distributed word representation, Unified Medical Language System semantic type, topic features, and features derived from consumer health vocabulary. We compared FOCUS with 2 strong baseline NLP systems. Physicians annotated 90 EHR notes and identified a mean of 9 (SD 5) important terms per note. The Cohen's kappa annotation agreement was .51. The 10-fold cross-validation results show that FOCUS achieved an area under the receiver operating characteristic curve (AUC-ROC) of 0.940 for ranking candidate terms from EHR notes to identify important terms. When including term identification, the performance of FOCUS for identifying important terms from EHR notes was 0.866 AUC-ROC. Both performance scores significantly exceeded the corresponding baseline system scores (P<.001). Rich learning features contributed to FOCUS's performance substantially. FOCUS can automatically rank terms from EHR notes based on their importance to patients. It may help develop future interventions that improve quality of care. ©Jinying Chen, Jiaping Zheng, Hong Yu. Originally published in JMIR Medical Informatics (http://medinform.jmir.org), 30.11.2016.

  4. Multispectral variable magnification glancing incidence x ray telescope

    NASA Technical Reports Server (NTRS)

    Hoover, Richard B. (Inventor)

    1992-01-01

    A multispectral, variable magnification, glancing incidence, x-ray telescope capable of broadband, high resolution imaging of solar and stellar x-ray and extreme ultraviolet radiation sources is discussed. The telescope includes a primary optical system which focuses the incoming radiation to a primary focus. Two or more rotatable mirror carriers, each providing a different magnification, are positioned behind the primary focus at an inclination to the optical axis. Each carrier has a series of ellipsoidal mirrors, and each mirror has a concave surface covered with a multilayer (layered synthetic microstructure) coating to reflect a different desired wavelength. The mirrors of both carriers are segments of ellipsoids having a common first focus coincident with the primary focus. A detector such as an x-ray sensitive photographic film is positioned at the second respective focus of each mirror so that each mirror may reflect the image at the first focus to the detector at the second focus. The carriers are selectively rotated to position a selected mirror for receiving radiation from the primary optical system, and at least the first carrier may be withdrawn from the path of the radiation to permit a selected mirror on the second carrier to receive the radiation.

  5. An Overview of FlamMap Fire Modeling Capabilities

    Treesearch

    Mark A. Finney

    2006-01-01

    Computerized and manual systems for modeling wildland fire behavior have long been available (Rothermel 1983, Andrews 1986). These systems focus on one-dimensional behaviors and assume the fire geometry is a spreading line-fire (in contrast with point or area-source fires). Models included in these systems were developed to calculate fire spread rate (Rothermel 1972,...

  6. Putting science into action on Forest Service Lands [Chapter 5

    Treesearch

    William M. Block; Victoria A. Saab; Leonard Ruggiero

    2012-01-01

    The U.S. Forest Service includes three main branches: National Forest Systems, Research and Development, and State and Private Forestry. Herein, we focus on National Forest Systems and Research and Development. National Forest Systems is the management branch of the agency, and its charge is to administer national forests and grasslands throughout the United States. A...

  7. System safety education focused on flight safety

    NASA Technical Reports Server (NTRS)

    Holt, E.

    1971-01-01

    The measures necessary for achieving higher levels of system safety are analyzed with an eye toward maintaining the combat capability of the Air Force. Several education courses were provided for personnel involved in safety management. Data include: (1) Flight Safety Officer Course, (2) Advanced Safety Program Management, (3) Fundamentals of System Safety, and (4) Quantitative Methods of Safety Analysis.

  8. CRISPR-FOCUS: A web server for designing focused CRISPR screening experiments.

    PubMed

    Cao, Qingyi; Ma, Jian; Chen, Chen-Hao; Xu, Han; Chen, Zhi; Li, Wei; Liu, X Shirley

    2017-01-01

    The recently developed CRISPR screen technology, based on the CRISPR/Cas9 genome editing system, enables genome-wide interrogation of gene functions in an efficient and cost-effective manner. Although many computational algorithms and web servers have been developed to design single-guide RNAs (sgRNAs) with high specificity and efficiency, algorithms specifically designed for conducting CRISPR screens are still lacking. Here we present CRISPR-FOCUS, a web-based platform to search and prioritize sgRNAs for CRISPR screen experiments. With official gene symbols or RefSeq IDs as the only mandatory input, CRISPR-FOCUS filters and prioritizes sgRNAs based on multiple criteria, including efficiency, specificity, sequence conservation, isoform structure, as well as genomic variations including Single Nucleotide Polymorphisms and cancer somatic mutations. CRISPR-FOCUS also provides pre-defined positive and negative control sgRNAs, as well as other necessary sequences in the construct (e.g., U6 promoters to drive sgRNA transcription and RNA scaffolds of the CRISPR/Cas9). These features allow users to synthesize oligonucleotides directly based on the output of CRISPR-FOCUS. Overall, CRISPR-FOCUS provides a rational and high-throughput approach for sgRNA library design that enables users to efficiently conduct a focused screen experiment targeting up to thousands of genes. (CRISPR-FOCUS is freely available at http://cistrome.org/crispr-focus/).

  9. Spacecraft 2000

    NASA Technical Reports Server (NTRS)

    1986-01-01

    The objective of the Workshop was to focus on the key technology area for 21st century spacecraft and the programs needed to facilitate technology development and validation. Topics addressed include: spacecraft systems; system development; structures and materials; thermal control; electrical power; telemetry, tracking, and control; data management; propulsion; and attitude control.

  10. Family-School Socialization: Problems and Prospects.

    ERIC Educational Resources Information Center

    Case Western Reserve Univ., Cleveland, OH. Inst. on the Family and the Bureaucratic Society.

    This document includes the proposal and implementation of a study focusing on the family's expectations, orientations, and cultural practices with regard to the educational system and the system's expectations, orientations and practices concerning the child and his family. The basic problem in this exploratory study is to describe analytically…

  11. Comparison of energy-based indicators used in life cycle assessment tools for buildings

    EPA Science Inventory

    Traditionally, building rating systems focused on, among others, energy used during operational stage. Recently, there is a strong push by these rating systems to include the life cycle energy use of buildings, particularly using Life Cycle Assessment (LCA), by offering credits t...

  12. Prioritizing Training To Maximize Results: The 3 Box System.

    ERIC Educational Resources Information Center

    Kearns, Paul

    2003-01-01

    Considers fundamentals of effective training and focuses on the evaluation of training. Describes the 3 Box System, which provides a framework for discussing: (1) basic training needs and priorities; (2) added value training, including ROI (return on investment); evaluation; and (3) prioritizing training budgets. (LRW)

  13. Materials Technical Team Roadmap

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    none,

    2013-08-01

    Roadmap identifying the efforts of the Materials Technical Team (MTT) to focus primarily on reducing the mass of structural systems such as the body and chassis in light-duty vehicles (including passenger cars and light trucks) which enables improved vehicle efficiency regardless of the vehicle size or propulsion system employed.

  14. Changing Rural Social Systems: Adaptation and Survival.

    ERIC Educational Resources Information Center

    Johnson, Nan E., Ed.; Wang, Ching-li, Ed.

    This book includes studies of globalization-related social changes in rural areas of the United States and other countries and implications of these studies for sociological theory. Although no chapter focuses exclusively on education, education-related themes include rural school dropouts and intergenerational poverty, the migration of rural…

  15. Facilitating Ambulatory Electronic Health Record System Implementation: Evidence from a Qualitative Study

    PubMed Central

    Hefner, Jennifer; Robbins, Julie; Huerta, Timothy R.

    2013-01-01

    Background. Ambulatory care practices have increasing interest in leveraging the capabilities of electronic health record (EHR) systems, but little information is available documenting how organizations have successfully implemented these systems. Objective. To characterize elements of successful electronic health record (EHR) system implementation and to synthesize the key informants' perspectives about successful implementation practices. Methods. Key informant interviews and focus groups were conducted with a purposive sample of individuals from US healthcare organizations identified for their success with ambulatory EHR implementation. Rigorous qualitative data analyses used both deductive and inductive methods. Results. Participants identified personal and system-related barriers, at both the individual and organization levels, including poor computer skills, productivity losses, resistance to change, and EHR system failure. Implementation success was reportedly facilitated by careful planning and consistent communication throughout distinct stages of the implementation process. A significant element of successful implementation was an emphasis on optimization, both during “go-live” and, subsequently, when users had more experience with the system. Conclusion. Successful EHR implementation requires both detailed planning and clear mechanisms to deal with unforeseen or unintended consequences. Focusing on user buy-in early and including plans for optimization can facilitate greater success. PMID:24228257

  16. Sensor Systems for Space Life Sciences

    NASA Technical Reports Server (NTRS)

    Somps, Chris J.; Hines, John W.; Connolly, John P. (Technical Monitor)

    1995-01-01

    Sensors 2000! (S2K!) is a NASA Ames Research Center engineering initiative designed to provide biosensor and bio-instrumentation systems technology expertise to NASA's life sciences spaceflight programs. S2K! covers the full spectrum of sensor technology applications, ranging from spaceflight hardware design and fabrication to advanced technology development, transfer and commercialization. S2K! is currently developing sensor systems for space biomedical applications on BION (a Russian biosatellite focused on Rhesus Monkey physiology) and NEUROLAB (a Space Shuttle flight devoted to neuroscience). It's Advanced Technology Development-Biosensors (ATD-B) project focuses efforts in five principle areas: biotelemetry Systems, chemical and biological sensors, physiological sensors, advanced instrumentation architectures, and data and information management. Technologies already developed and tested included, application-specific sensors, preamplifier hybrids, modular programmable signal conditioners, power conditioning and distribution systems, and a fully implantable dual channel biotelemeter. Systems currently under development include a portable receiver system compatible with an off-the-shelf analog biotelemeter, a 4 channel digital biotelemetry system which monitors pH, a multichannel, g-processor based PCM biotelemetry system, and hand-held personal monitoring systems. S2K! technology easily lends itself to telescience and telemedicine applications as a front-end measurement and data acquisition device, suitable for obtaining and configuring physiological information, and processing that information under control from a remote location.

  17. NATO Human View Architecture and Human Networks

    NASA Technical Reports Server (NTRS)

    Handley, Holly A. H.; Houston, Nancy P.

    2010-01-01

    The NATO Human View is a system architectural viewpoint that focuses on the human as part of a system. Its purpose is to capture the human requirements and to inform on how the human impacts the system design. The viewpoint contains seven static models that include different aspects of the human element, such as roles, tasks, constraints, training and metrics. It also includes a Human Dynamics component to perform simulations of the human system under design. One of the static models, termed Human Networks, focuses on the human-to-human communication patterns that occur as a result of ad hoc or deliberate team formation, especially teams distributed across space and time. Parameters of human teams that effect system performance can be captured in this model. Human centered aspects of networks, such as differences in operational tempo (sense of urgency), priorities (common goal), and team history (knowledge of the other team members), can be incorporated. The information captured in the Human Network static model can then be included in the Human Dynamics component so that the impact of distributed teams is represented in the simulation. As the NATO militaries transform to a more networked force, the Human View architecture is an important tool that can be used to make recommendations on the proper mix of technological innovations and human interactions.

  18. Software architecture and engineering for patient records: current and future.

    PubMed

    Weng, Chunhua; Levine, Betty A; Mun, Seong K

    2009-05-01

    During the "The National Forum on the Future of the Defense Health Information System," a track focusing on "Systems Architecture and Software Engineering" included eight presenters. These presenters identified three key areas of interest in this field, which include the need for open enterprise architecture and a federated database design, net centrality based on service-oriented architecture, and the need for focus on software usability and reusability. The eight panelists provided recommendations related to the suitability of service-oriented architecture and the enabling technologies of grid computing and Web 2.0 for building health services research centers and federated data warehouses to facilitate large-scale collaborative health care and research. Finally, they discussed the need to leverage industry best practices for software engineering to facilitate rapid software development, testing, and deployment.

  19. Geothermal systems

    NASA Technical Reports Server (NTRS)

    Mohl, C.

    1978-01-01

    Several tasks of JPL related to geothermal energy are discussed. The major task is the procurement and test and evaluation of a helical screw drive (wellhead unit). A general review of geothermal energy systems is given. The presentation focuses attention on geothermal reservoirs in California, with graphs and charts to support the discussion. Included are discussions on cost analysis, systems maintenance, and a comparison of geothermal and conventional heating and cooling systems.

  20. Early Warning/Track-and-Trigger Systems to Detect Deterioration and Improve Outcomes in Hospitalized Patients.

    PubMed

    Shiloh, Ariel L; Lominadze, George; Gong, Michelle N; Savel, Richard H

    2016-02-01

    As a global effort toward improving patient safety, a specific area of focus has been the early recognition and rapid intervention in deteriorating ward patients. This focus on "failure to rescue" has led to the construction of early warning/track-and-trigger systems. In this review article, we present a description of the data behind the creation and implementation of such systems, including multiple algorithms and strategies for deployment. Additionally, the strengths and weaknesses of the various systems and their evaluation in the literature are emphasized. Despite the limitations of the current literature, the potential benefit of these early warning/track-and-trigger systems to improve patient outcomes remains significant. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

  1. Ethics and the UN Sustainable Development Goals: The Case for Comprehensive Engineering : Commentary on "Using Student Engagement to Relocate Ethics to the Core of the Engineering Curriculum".

    PubMed

    van den Hoven, Jeroen

    2016-12-27

    In the twenty-first century, the urgent problems the world is facing (the UN Sustainable Development Goals) are increasingly related to vast and intricate 'systems of systems', which comprise both socio-technical and eco-systems. In order for engineers to adequately and responsibly respond to these problems, they cannot focus on only one technical or any other aspect in isolation, but must adopt a wider and multidisciplinary perspective of these systems, including an ethical and social perspective. Engineering curricula should therefore focus on what we call 'comprehensive engineering'. Comprehensive engineering implies ethical coherence, consilience of scientific disciplines, and cooperation between parties.

  2. Integrated Earth System Model (iESM)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Thornton, Peter Edmond; Mao, Jiafu; Shi, Xiaoying

    2016-12-02

    The iESM is a simulation code that represents the physical and biological aspects of Earth's climate system, and also includes the macro-economic and demographic properties of human societies. The human aspect of the simulation code is focused in particular on the effects of human activities on land use and land cover change, but also includes aspects such as energy economies. The time frame for predictions with iESM is approximately 1970 through 2100.

  3. The North American Energy System: Overview of the 3rd Chapter of SOCCR-2

    NASA Astrophysics Data System (ADS)

    Marcotullio, P. J.

    2016-12-01

    North America, including Canada, Mexico and the United States, has a large and complex energy system, which includes the extraction and conversion of primary energy sources and their storage, transmission, distribution and ultimate end use in the building, transportation and industrial sectors. The chapter overviews this system focusing on our understanding of the energy trends and system feedback dynamics, key drivers of change, and subsequent carbon emissions and the basis for carbon management. We also put the carbon emissions from the North American system in global context. Highlights include the changes to the system (sources, fuel mix, drivers, infrastructure, etc.,) over the past decade, and a review of scenarios that provide glimpses into future emissions levels and meeting the requirements for decarbonization in the medium and longer term.

  4. Surface Habitat Systems

    NASA Technical Reports Server (NTRS)

    Kennedy, Kriss J.

    2009-01-01

    The Surface Habitat Systems (SHS) Focused Investment Group (FIG) is part of the National Aeronautics and Space Administration (NASA) Johnson Space Center (JSC) effort to provide a focused direction and funding to the various projects that are working on human surface habitat designs and technologies for the planetary exploration missions. The overall SHS-FIG effort focuses on directing and guiding those projects that: 1) develop and demonstrate new surface habitat system concepts, innovations, and technologies to support human exploration missions, 2) improve environmental systems that interact with human habitats, 3) handle and emplace human surface habitats, and 4) focus on supporting humans living and working in habitats on planetary surfaces. The activity areas of the SHS FIG described herein are focused on the surface habitat project near-term objectives as described in this document. The SHS-FIG effort focuses on mitigating surface habitat risks (as identified by the Lunar Surface Systems Project Office (LSSPO) Surface Habitat Element Team; and concentrates on developing surface habitat technologies as identified in the FY08 gap analysis. The surface habitat gap assessment will be updated annually as the surface architecture and surface habitat definition continues to mature. These technologies are mapped to the SHS-FIG Strategic Development Roadmap. The Roadmap will bring to light the areas where additional innovative efforts are needed to support the development of habitat concepts and designs and the development of new technologies to support of the LSSPO Habitation Element development plan. Three specific areas of development that address Lunar Architecture Team (LAT)-2 and Constellation Architecture Team (CxAT) Lunar habitat design issues or risks will be focused on by the SHS-FIG. The SHS-FIG will establish four areas of development that will help the projects prepare in their planning for surface habitat systems development. Those development areas are the 1) surface habitat concept definition, 2) inflatable surface habitat development, and 3) autonomous habitat operations, and 4) cross-cutting / systems engineering. In subsequent years, the SHS-FIG will solicit a call for innovations and technologies that will support the development of these four development areas. The other development areas will be assessed yearly and identified on the SHS-FIG s Strategic Development Roadmap. Initial investment projects that are funded by the Constellation Program Office (CxPO), LSSPO, or the Exploration Technology Development Projects (ETDP) will also be included on the Roadmap. For example, in one or two years from now, the autonomous habitat operations and testbed would collaborations with the Integrated Systems Health Management (ISHM) and Automation for Operations ETDP projects, which will give the surface habitat projects an integrated habitat autonomy testbed to test software and systems. The SHS-FIG scope is to provide focused direction for multiple innovations, technologies and subsystems that are needed to support humans at a remote planetary surface habitat during the concept development, design definition, and integration phases of that project. Subsystems include: habitability, lightweight structures, power management, communications, autonomy, deployment, outfitting, life support, wireless connectivity, lighting, thermal and more.

  5. Atmospheric Infrasound during a Large Wildfire

    NASA Astrophysics Data System (ADS)

    Vance, Alexis; Elbing, Brian

    2017-11-01

    Numerous natural and manmade sources generate infrasound, including tornado producing storms, human heart, hurricanes, and volcanoes. Infrasound is currently being studied as part of Collaboration Leading Operational UAS Development for Meteorology and Atmospheric Physics (CLOUD MAP), which is a multi-university collaboration focused on development and implementation of unmanned aircraft systems (UAS) and integration with sensors for atmospheric measurements. To support this effort a fixed infrasonic microphone located in Stillwater, Oklahoma has been monitoring atmospheric emissions since September of 2016. While severe storm systems is the primary focus of this work, the system also captures a wide range of infrasonic sources from distances in excess of 300 miles due to an acoustic ceiling and weak atmospheric absorption. The current presentation will focus on atmospheric infrasound observations during a large wildfire on the Kansas-Oklahoma border that occurred between March 6-22, 2017. This work was supported by NSF Grant 1539070.

  6. Recommendations to guide revision of the Guides to the Evaluation of Permanent Impairment. American Medical Association.

    PubMed

    Spieler, E A; Barth, P S; Burton, J F; Himmelstein, J; Rudolph, L

    2000-01-26

    The American Medical Association's Guides to the Evaluation of Permanent Impairment, Fourth Edition, is the most commonly used tool in the United States for rating permanent impairments for disability systems. The Guides, currently undergoing revision, has been the focus of considerable controversy. Criticisms have focused on 2 areas: internal deficiencies, including the lack of a comprehensive, valid, reliable, unbiased, and evidence-based system for rating impairments; and the way in which workers' compensation systems use the ratings, resulting in inappropriate compensation. We focus on the internal deficiencies and recommend that the Guides remains a tool for evaluation of permanent impairment, not disability. To maintain wide acceptance of the Guides, its authors need to improve the validity, internal consistency, and comprehensiveness of the ratings; document reliability and reproducibility of the results; and make the Guides easily comprehensible and accessible to physicians.

  7. Vocational Rehabilitation: An Employment Program. Hearing on Examining the Vocational Rehabilitation System and the Rehabilitation Act, Focusing Slightly and Explore Some of the Issues, Including Linkage, the VR System Faces in Ohio, (Columbus, OH) before the Subcommittee on Employment and Training of the Committee on Labor and Human Resources. United States Senate, One Hundred Fifth Congress, First Session.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Senate Committee on Labor and Human Resources.

    This congressional report contains testimony examining the vocational rehabilitation system and the Vocational Rehabilitation Act and exploring some of the issues, including linkage, faced by the vocational rehabilitation system in Ohio. Statements were provided by a U.S. senator (Mike DeWine, Ohio) and representatives of the following agencies…

  8. Supply Chain Collaboration Alternatives: Understanding the Expected Costs and Benefits.

    ERIC Educational Resources Information Center

    McLaren, Tim; Head, Milena; Yuan, Yufei

    2002-01-01

    Discusses collaboration as a recent trend in supply chain management (SCM) that focuses on joint planning, coordination, and process integration between suppliers, customers, and other partners in a supply chain. Analyzes alternative information systems approaches for supporting collaborative SCM, including phone, fax, or email systems; Web-based…

  9. Electrically conducting polymers for aerospace applications

    NASA Technical Reports Server (NTRS)

    Meador, Mary Ann B.; Gaier, James R.; Good, Brian S.; Sharp, G. R.; Meador, Michael A.

    1991-01-01

    Current research on electrically conducting polymers from 1974 to the present is reviewed focusing on the development of materials for aeronautic and space applications. Problems discussed include extended pi-systems, pyrolytic polymers, charge-transfer systems, conductive matrix resins for composite materials, and prospects for the use of conducting polymers in space photovoltaics.

  10. Exploring Regularities and Dynamic Systems in L2 Development

    ERIC Educational Resources Information Center

    Lenzing, Anke

    2015-01-01

    This article focuses on a theoretical and empirical exploration of developmental trajectories and individual learner variation in second language (L2) acquisition. Taking a processability perspective, I view learner language as a dynamic system that includes predictable universal developmental trajectories as well as individual learner variation,…

  11. Preparing for an Even Brighter Future

    ERIC Educational Resources Information Center

    Puri, Rajeev

    2005-01-01

    This article discusses the future of America's education system. In 1983, the National Commission on Excellence in Education's report A Nation at Risk raised questions about whether America's education system was endangering America's competitive future. This prompted a wave of reforms in education, including a stronger focus on the effective use…

  12. Nanomaterials for Advanced Life Support in Advanced Life Support in Space systems

    NASA Technical Reports Server (NTRS)

    Allada, Rama Kumar; Moloney, Padraig; Yowell, Leonard

    2006-01-01

    A viewgraph presentation describing nanomaterial research at NASA Johnson Space Center with a focus on advanced life support in space systems is shown. The topics include: 1) Introduction; 2) Research and accomplishments in Carbon Dioxide Removal; 3) Research and Accomplishments in Water Purification; and 4) Next Steps

  13. Content Appraisal as a Method for Measuring the Effectiveness & Usability of Online Content

    ERIC Educational Resources Information Center

    Nadeau, Jenifer; Heidorn, Neely; Broady, Nick; Whittle, Jennifer

    2012-01-01

    Content appraisal is a simple, qualitative system to identify modifications to make website material more useful to clientele. This system provides a comprehensive evaluation of content, focuses on content strategy, identifies weaknesses, and provides recommendations for improvement. The criteria examined included knowledge level,…

  14. On Inference Rules of Logic-Based Information Retrieval Systems.

    ERIC Educational Resources Information Center

    Chen, Patrick Shicheng

    1994-01-01

    Discussion of relevance and the needs of the users in information retrieval focuses on a deductive object-oriented approach and suggests eight inference rules for the deduction. Highlights include characteristics of a deductive object-oriented system, database and data modeling language, implementation, and user interface. (Contains 24…

  15. Experimental and Computational Investigation of Microbubble Production in Microfluidic Flow-Focusing Devices

    NASA Astrophysics Data System (ADS)

    Weber, Michael; Shandas, Robin

    2005-11-01

    Micron-sized bubbles have been effectively used as contrast agents in ultrasound imaging systems and have the potential for many other applications including targeted drug delivery and tumor destruction. The further development of these applications is dependent on precise control of bubble size. Recently, microfluidic flow-focusing systems have emerged as a viable means of producing microbubbles with monodisperse size distributions. These systems focus co-flowing liquid streams surrounding a gas stream through a narrow orifice, producing bubbles in very reproducible manner. In this work, a photopolymerization technique has been used to produce microfludicic flow-focusing devices which were successfully used to produce micron-sized bubbles. The flow dynamics involved in these devices has also been simulated using a volume-of-fluid approach to simultaneously solve the equations of motion for both the gas and liquid phases. Simulations were run with several variations of the flow-focuser geometry (gas inlet width, orifice length, gas-liquid approach angle, etc.) in an effort to produce smaller bubbles and increase the working range of liquid and gas flow rates. These findings are being incorporated into the production of actual devices in an effort to improve the overall effectiveness of the bubble production process.

  16. Information Technology, Campus Libraries, and Patrons with Disabilities: Emerging issues and Access Strategies.

    ERIC Educational Resources Information Center

    Hilton-Chalfen, Danny

    1992-01-01

    Discussion of the potential for academic libraries to provide improved opportunities for patrons with disabilities focuses on access to online information, including online catalogs, campuswide information systems, CD-ROM products, graphical user interfaces, and electronic documents. Other considerations include location of online resources,…

  17. Teaching with Distance Delivery Systems: Strategies from Alpha to Omega.

    ERIC Educational Resources Information Center

    Rezabek, Landra L.

    Distance education can assume many forms, including videotaped lectures, computer-mediated communication among teacher and student, and instantaneous, live two-way interaction. This paper focuses on tips and strategies for educators wishing to expand their teaching repertoires to include the use of these technologies. Teacher strategies listed…

  18. The Privilege of Ranking: Google Plays Ball.

    ERIC Educational Resources Information Center

    Wiggins, Richard

    2003-01-01

    Discussion of ranking systems used in various settings, including college football and academic admissions, focuses on the Google search engine. Explains the PageRank mathematical formula that scores Web pages by connecting the number of links; limitations, including authenticity and accuracy of ranked Web pages; relevancy; adjusting algorithms;…

  19. Imaging based refractometers

    DOEpatents

    Baba, Justin S.

    2015-11-24

    Refractometers for simultaneously measuring refractive index of a sample over a range or wavelengths of light include dispersive and focusing optical systems. An optical beam including the rang of wavelengths is spectrally spread along a first axis and focused along a second axis so as to be incident to an interface between the sample and a prism at a range of angles of incidence including a critical angle for at least one wavelength. In some cases, the prism can have a triangle, parallelogram, trapezoid, or other shape. In some cases, the optical beam can be reflected off of multiple interfaces between the prism and the sample. An imaging detector is situated to receive the spectrally spread and focused light from the interface and form an image corresponding to angle of incidence as a function of wavelength. One or more critical angles are indentified and corresponding refractive indices are determined.

  20. The marginal band system in nymphalid butterfly wings.

    PubMed

    Taira, Wataru; Kinjo, Seira; Otaki, Joji M

    2015-01-01

    Butterfly wing color patterns are highly complex and diverse, but they are believed to be derived from the nymphalid groundplan, which is composed of several color pattern systems. Among these pattern systems, the marginal band system, including marginal and submarginal bands, has rarely been studied. Here, we examined the color pattern diversity of the marginal band system among nymphalid butterflies. Marginal and submarginal bands are usually expressed as a pair of linear bands aligned with the wing margin. However, a submarginal band can be expressed as a broken band, an elongated oval, or a single dot. The marginal focus, usually a white dot at the middle of a wing compartment along the wing edge, corresponds to the pupal edge spot, one of the pupal cuticle spots that signify the locations of color pattern organizing centers. A marginal band can be expressed as a semicircle, an elongated oval, or a pair of eyespot-like structures, which suggest the organizing activity of the marginal focus. Physical damage at the pupal edge spot leads to distal dislocation of the submarginal band in Junonia almana and in Vanessa indica, suggesting that the marginal focus functions as an organizing center for the marginal band system. Taken together, we conclude that the marginal band system is developmentally equivalent to other symmetry systems. Additionally, the marginal band is likely a core element and the submarginal band a paracore element of the marginal band system, and both bands are primarily specified by the marginal focus organizing center.

  1. Performance of an underwater acoustic volume array using time-reversal focusing.

    PubMed

    Root, Joseph A; Rogers, Peter H

    2002-11-01

    Time reversal permits acoustic focusing and beam forming in inhomogeneous and/or high-scattering environments. A volumetric array geometry can suppress back lobes and can fit a large, powerful array of elements into small spaces, like the free-water spaces on submarines. This research investigates applying the time-reversal method to an underwater acoustic volume array. The experiments evaluate the focusing performance of a 27-element volume array when different scattering structures are present within the volume of the array. The array is arranged in a 3x3x3 cubic matrix configuration with 18.75-cm vertical and horizontal element spacing. The system utilizes second-derivative Gaussian pulses to focus on a point 30 cm from the array. Results include a comparison between time-reversal focusing and standard focusing, an evaluation of the volume array's ability to suppress back lobes, and an analysis of how different scattering environments affect focal region size. Potential underwater applications for a volume array using time reversal include acoustic imaging, naval mine hunting, sonar, and underwater communications.

  2. Performance of an underwater acoustic volume array using time-reversal focusing

    NASA Astrophysics Data System (ADS)

    Root, Joseph A.; Rogers, Peter H.

    2002-11-01

    Time reversal permits acoustic focusing and beam forming in inhomogeneous and/or high-scattering environments. A volumetric array geometry can suppress back lobes and can fit a large, powerful array of elements into small spaces, like the free-water spaces on submarines. This research investigates applying the time-reversal method to an underwater acoustic volume array. The experiments evaluate the focusing performance of a 27-element volume array when different scattering structures are present within the volume of the array. The array is arranged in a 3 x3 x3 cubic matrix configuration with 18.75-cm vertical and horizontal element spacing. The system utilizes second-derivative Gaussian pulses to focus on a point 30 cm from the array. Results include a comparison between time-reversal focusing and standard focusing, an evaluation of the volume array's ability to suppress back lobes, and an analysis of how different scattering environments affect focal region size. Potential underwater applications for a volume array using time reversal include acoustic imaging, naval mine hunting, sonar, and underwater communications. copyright 2002 Acoustical Society of America.

  3. The effects of caffeine on the cholinergic system.

    PubMed

    Pohanka, Miroslav

    2014-01-01

    Caffeine is a secondary metabolite of tea and coffee plants. It is the active psychostimulant ingredient of widely consumed beverages, chocolate and some drugs as well. The major pathways for caffeine including interaction with adenosine receptors have been identified but caffeine has several minor pathways as well that remain poorly understood including the cholinergic system. Given the role of caffeine in the cholinergic system, some molecular targets have been tracked and a mechanism of its action has been proposed in research studies. However, the biological effect of caffeine on the cholinergic system is not completely understood. The present review focuses on the role of caffeine in the cholinergic system.

  4. Research on Life Science and Life Support Engineering Problems of Manned Deep Space Exploration Mission

    NASA Astrophysics Data System (ADS)

    Qi, Bin; Guo, Linli; Zhang, Zhixian

    2016-07-01

    Space life science and life support engineering are prominent problems in manned deep space exploration mission. Some typical problems are discussed in this paper, including long-term life support problem, physiological effect and defense of varying extraterrestrial environment. The causes of these problems are developed for these problems. To solve these problems, research on space life science and space medical-engineering should be conducted. In the aspect of space life science, the study of space gravity biology should focus on character of physiological effect in long term zero gravity, co-regulation of physiological systems, impact on stem cells in space, etc. The study of space radiation biology should focus on target effect and non-target effect of radiation, carcinogenicity of radiation, spread of radiation damage in life system, etc. The study of basic biology of space life support system should focus on theoretical basis and simulating mode of constructing the life support system, filtration and combination of species, regulation and optimization method of life support system, etc. In the aspect of space medical-engineering, the study of bio-regenerative life support technology should focus on plants cultivation technology, animal-protein production technology, waste treatment technology, etc. The study of varying gravity defense technology should focus on biological and medical measures to defend varying gravity effect, generation and evaluation of artificial gravity, etc. The study of extraterrestrial environment defense technology should focus on risk evaluation of radiation, monitoring and defending of radiation, compound prevention and removal technology of dust, etc. At last, a case of manned lunar base is analyzed, in which the effective schemes of life support system, defense of varying gravity, defense of extraterrestrial environment are advanced respectively. The points in this paper can be used as references for intensive study on key technologies.

  5. Detection technique of targets for missile defense system

    NASA Astrophysics Data System (ADS)

    Guo, Hua-ling; Deng, Jia-hao; Cai, Ke-rong

    2009-11-01

    Ballistic missile defense system (BMDS) is a weapon system for intercepting enemy ballistic missiles. It includes ballistic-missile warning system, target discrimination system, anti-ballistic-missile guidance systems, and command-control communication system. Infrared imaging detection and laser imaging detection are widely used in BMDS for surveillance, target detection, target tracking, and target discrimination. Based on a comprehensive review of the application of target-detection techniques in the missile defense system, including infrared focal plane arrays (IRFPA), ground-based radar detection technology, 3-dimensional imaging laser radar with a photon counting avalanche photodiode (APD) arrays and microchip laser, this paper focuses on the infrared and laser imaging detection techniques in missile defense system, as well as the trends for their future development.

  6. Immunotoxicity Studies

    EPA Science Inventory

    Immunotoxicology is a subdiscipline of toxicology that focuses on unintended modulation of the immune system. Effects that may occur include immunosuppression, immunostimulation, hypersensitivity, or autoimmunity, which may result in outcomes such as increased incidences of infec...

  7. NASA Tech Briefs, August 2002. Volume 26, No. 8

    NASA Technical Reports Server (NTRS)

    2002-01-01

    Topics include: a technology focus on computers, electronic components and systems, software, materials, mechanics, machinery/automation, manufacturing, physical sciences, information sciences, book and reports, and Motion control Tech Briefs.

  8. Focus groups inform a web-based program to increase fruit and vegetable intake.

    PubMed

    Rolnick, Sharon J; Calvi, Josephine; Heimendinger, Jerianne; McClure, Jennifer B; Kelley, Mary; Johnson, Christine; Alexander, Gwen L

    2009-11-01

    To use focus groups to inform a web-based educational intervention for increased fruit and vegetable (FV) consumption. Twelve groups (participants=137, aged 21-65) were recruited from four geographically diverse health systems. Four groups were stratified by gender and eight by race (white and African American) and gender. Questions included perceptions of healthy eating, factors that encourage or serve as barriers to FV consumption and features preferred for a web-based educational intervention. Though knowledgeable about healthy eating, participants did not know how to achieve or always care about healthy nutritional choices. Motivators for FV consumption included being role models and health concerns. Barriers included: lack of time, expense and FV availability. Website preferences included: visuals, links, tailored materials, menu suggestions, goal setting assistance, printable summaries and built in motivation. The developers incorporated nearly all suggestions. Focus groups provided needs-based tactical strategies for an online, education intervention targeting factors to improve FV consumption. Focus groups can provide valuable input to inform interventions. Further, web-based programs' abilities to offer information without time or geographic constraints, with capacity for tailoring and tracking progress makes them a valuable addition in the arsenal of efforts to promote healthy behaviors.

  9. Fishing for resilience

    USGS Publications Warehouse

    Pope, Kevin L.; Allen, Craig R.; Angeler, David G.

    2014-01-01

    Management approaches that focus on social–ecological systems—systems comprised of ecosystems, landscapes, and humans—are needed to secure the sustainability of inland recreational fisheries without jeopardizing the integrity of the underlying social and ecological components. Resilience management can be useful because it focuses on providing recreational capacity for fishermen under a variety of conditions while assuring that the social–ecological system is not pushed to a critical threshold that would result in a new, undesired system regime. Resilience management is based on a system perspective that accounts for the possible regimes a system could manifest. It aims to enhance system properties that allow continued maintenance of the system in a desired regime in which multiple goods and services, including recreational capacity, are provided. In this forum paper, we provide an overview of the potential of a resilience approach to the management of recreational fisheries and highlight the scientific and administrative challenges to its successful implementation.

  10. Crew Health Care System (CHeCS) Design Research, Documentations, and Evaluations

    NASA Technical Reports Server (NTRS)

    CLement, Bethany M.

    2011-01-01

    The Crew Health Care System (CHeCS) is a group within the Space Life Science Directorate (SLSD) that focuses on the overall health of astronauts by reinforcing the three divisions - the Environmental Maintenance System (EMS), the Countermeasures System (CMS), and the Health Maintenance System (HMS). This internship provided opportunity to gain knowledge, experience, and skills in CHeCS engineering and operations tasks. Various and differing tasks allowed for occasions to work independently, network to get things done, and show leadership abilities. Specific exercises included reviewing hardware certification, operations, and documentation within the ongoing Med Kit Redesign (MKR) project, and learning, writing, and working various common pieces of paperwork used in the engineering and design process. Another project focused on the distribution of various pieces of hardware to off-site research facilities with an interest in space flight health care. The main focus of this internship, though, was on a broad and encompassing understanding of the engineering process as time was spent looking at each individual step in a variety of settings and tasks.

  11. Remote gaze tracking system on a large display.

    PubMed

    Lee, Hyeon Chang; Lee, Won Oh; Cho, Chul Woo; Gwon, Su Yeong; Park, Kang Ryoung; Lee, Heekyung; Cha, Jihun

    2013-10-07

    We propose a new remote gaze tracking system as an intelligent TV interface. Our research is novel in the following three ways: first, because a user can sit at various positions in front of a large display, the capture volume of the gaze tracking system should be greater, so the proposed system includes two cameras which can be moved simultaneously by panning and tilting mechanisms, a wide view camera (WVC) for detecting eye position and an auto-focusing narrow view camera (NVC) for capturing enlarged eye images. Second, in order to remove the complicated calibration between the WVC and NVC and to enhance the capture speed of the NVC, these two cameras are combined in a parallel structure. Third, the auto-focusing of the NVC is achieved on the basis of both the user's facial width in the WVC image and a focus score calculated on the eye image of the NVC. Experimental results showed that the proposed system can be operated with a gaze tracking accuracy of ±0.737°~±0.775° and a speed of 5~10 frames/s.

  12. Remote Gaze Tracking System on a Large Display

    PubMed Central

    Lee, Hyeon Chang; Lee, Won Oh; Cho, Chul Woo; Gwon, Su Yeong; Park, Kang Ryoung; Lee, Heekyung; Cha, Jihun

    2013-01-01

    We propose a new remote gaze tracking system as an intelligent TV interface. Our research is novel in the following three ways: first, because a user can sit at various positions in front of a large display, the capture volume of the gaze tracking system should be greater, so the proposed system includes two cameras which can be moved simultaneously by panning and tilting mechanisms, a wide view camera (WVC) for detecting eye position and an auto-focusing narrow view camera (NVC) for capturing enlarged eye images. Second, in order to remove the complicated calibration between the WVC and NVC and to enhance the capture speed of the NVC, these two cameras are combined in a parallel structure. Third, the auto-focusing of the NVC is achieved on the basis of both the user's facial width in the WVC image and a focus score calculated on the eye image of the NVC. Experimental results showed that the proposed system can be operated with a gaze tracking accuracy of ±0.737°∼±0.775° and a speed of 5∼10 frames/s. PMID:24105351

  13. Finding Important Terms for Patients in Their Electronic Health Records: A Learning-to-Rank Approach Using Expert Annotations

    PubMed Central

    Zheng, Jiaping; Yu, Hong

    2016-01-01

    Background Many health organizations allow patients to access their own electronic health record (EHR) notes through online patient portals as a way to enhance patient-centered care. However, EHR notes are typically long and contain abundant medical jargon that can be difficult for patients to understand. In addition, many medical terms in patients’ notes are not directly related to their health care needs. One way to help patients better comprehend their own notes is to reduce information overload and help them focus on medical terms that matter most to them. Interventions can then be developed by giving them targeted education to improve their EHR comprehension and the quality of care. Objective We aimed to develop a supervised natural language processing (NLP) system called Finding impOrtant medical Concepts most Useful to patientS (FOCUS) that automatically identifies and ranks medical terms in EHR notes based on their importance to the patients. Methods First, we built an expert-annotated corpus. For each EHR note, 2 physicians independently identified medical terms important to the patient. Using the physicians’ agreement as the gold standard, we developed and evaluated FOCUS. FOCUS first identifies candidate terms from each EHR note using MetaMap and then ranks the terms using a support vector machine-based learn-to-rank algorithm. We explored rich learning features, including distributed word representation, Unified Medical Language System semantic type, topic features, and features derived from consumer health vocabulary. We compared FOCUS with 2 strong baseline NLP systems. Results Physicians annotated 90 EHR notes and identified a mean of 9 (SD 5) important terms per note. The Cohen’s kappa annotation agreement was .51. The 10-fold cross-validation results show that FOCUS achieved an area under the receiver operating characteristic curve (AUC-ROC) of 0.940 for ranking candidate terms from EHR notes to identify important terms. When including term identification, the performance of FOCUS for identifying important terms from EHR notes was 0.866 AUC-ROC. Both performance scores significantly exceeded the corresponding baseline system scores (P<.001). Rich learning features contributed to FOCUS’s performance substantially. Conclusions FOCUS can automatically rank terms from EHR notes based on their importance to patients. It may help develop future interventions that improve quality of care. PMID:27903489

  14. The SIMPSONS project: An integrated Mars transportation system

    NASA Astrophysics Data System (ADS)

    Kaplan, Matthew; Carlson, Eric; Bradfute, Sherie; Allen, Kent; Duvergne, Francois; Hernandez, Bert; Le, David; Nguyen, Quan; Thornhill, Brett

    In response to the Request for Proposal (RFP) for an integrated transportation system network for an advanced Martian base, Frontier Transportation Systems (FTS) presents the results of the SIMPSONS project (Systems Integration for Mars Planetary Surface Operations Networks). The following topics are included: the project background, vehicle design, future work, conclusions, management status, and cost breakdown. The project focuses solely on the surface-to-surface transportation at an advanced Martian base.

  15. The SIMPSONS project: An integrated Mars transportation system

    NASA Technical Reports Server (NTRS)

    Kaplan, Matthew; Carlson, Eric; Bradfute, Sherie; Allen, Kent; Duvergne, Francois; Hernandez, Bert; Le, David; Nguyen, Quan; Thornhill, Brett

    1992-01-01

    In response to the Request for Proposal (RFP) for an integrated transportation system network for an advanced Martian base, Frontier Transportation Systems (FTS) presents the results of the SIMPSONS project (Systems Integration for Mars Planetary Surface Operations Networks). The following topics are included: the project background, vehicle design, future work, conclusions, management status, and cost breakdown. The project focuses solely on the surface-to-surface transportation at an advanced Martian base.

  16. Hiding the system from the user: Moving from complex mental models to elegant metaphors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Curtis W. Nielsen; David J. Bruemmer

    2007-08-01

    In previous work, increased complexity of robot behaviors and the accompanying interface design often led to operator confusion and/or a fight for control between the robot and operator. We believe the reason for the conflict was that the design of the interface and interactions presented too much of the underlying robot design model to the operator. Since the design model includes the implementation of sensors, behaviors, and sophisticated algorithms, the result was that the operator’s cognitive efforts were focused on understanding the design of the robot system as opposed to focusing on the task at hand. This paper illustrates howmore » this very problem emerged at the INL and how the implementation of new metaphors for interaction has allowed us to hide the design model from the user and allow the user to focus more on the task at hand. Supporting the user’s focus on the task rather than on the design model allows increased use of the system and significant performance improvement in a search task with novice users.« less

  17. Tritium Breeding Blanket for a Commercial Fusion Power Plant - A System Engineering Assessment

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Meier, Wayne R.

    The goal of developing a new source of electric power based on fusion has been pursued for decades. If successful, future fusion power plants will help meet growing world-wide demand for electric power. A key feature and selling point for fusion is that its fuel supply is widely distributed globally and virtually inexhaustible. Current world-wide research on fusion energy is focused on the deuterium-tritium (DT for short) fusion reaction since it will be the easiest to achieve in terms of the conditions (e.g., temperature, density and confinement time of the DT fuel) required to produce net energy. Over the pastmore » decades countless studies have examined various concepts for TBBs for both magnetic fusion energy (MFE) and inertial fusion energy (IFE). At this time, the key organizations involved are government sponsored research organizations world-wide. The near-term focus of the MFE community is on the development of TBB mock-ups to be tested on the ITER tokamak currently under construction in Caderache France. TBB concepts for IFE tend to be different from MFE primarily due to significantly different operating conditions and constraints. This report focuses on longer-term commercial power plants where the key stakeholders include: electric utilities, plant owner and operator, manufacturer, regulators, utility customers, and in-plant subsystems including the heat transfer and conversion systems, fuel processing system, plant safety systems, and the monitoring control systems.« less

  18. Ion beam accelerator system

    NASA Technical Reports Server (NTRS)

    Aston, Graeme (Inventor)

    1984-01-01

    A system is described that combines geometrical and electrostatic focusing to provide high ion extraction efficiency and good focusing of an accelerated ion beam. The apparatus includes a pair of curved extraction grids (16, 18) with multiple pairs of aligned holes positioned to direct a group of beamlets (20) along converging paths. The extraction grids are closely spaced and maintained at a moderate potential to efficiently extract beamlets of ions and allow them to combine into a single beam (14). An accelerator electrode device (22) downstream from the extraction grids, is at a much lower potential than the grids to accelerate the combined beam.

  19. Theoretical studies in isoelectric focusing. [mathematical modeling and computer simulation for biologicals purification process

    NASA Technical Reports Server (NTRS)

    Mosher, R. A.; Palusinski, O. A.; Bier, M.

    1982-01-01

    A mathematical model has been developed which describes the steady state in an isoelectric focusing (IEF) system with ampholytes or monovalent buffers. The model is based on the fundamental equations describing the component dissociation equilibria, mass transport due to diffusion and electromigration, electroneutrality, and the conservation of charge. The validity and usefulness of the model has been confirmed by using it to formulate buffer systems in actual laboratory experiments. The model has been recently extended to include the evolution of transient states not only in IEF but also in other modes of electrophoresis.

  20. Applications of MEMS for Space Exploration

    NASA Astrophysics Data System (ADS)

    Tang, William C.

    1998-03-01

    Space exploration in the coming century will emphasize cost effectiveness and highly focused mission objectives, which will result in frequent multiple missions that broaden the scope of space science and to validate new technologies on a timely basis. Micro Electro Mechanical Systems (MEMS) is one of the key enabling technologies to create cost-effective, ultra-miniaturized, robust, and functionally focused spacecraft for both robotic and human exploration programs. Examples of MEMS devices at various stages of development include microgyroscope, microseismometer, microhygrometer, quadrupole mass spectrometer, and micropropulsion engine. These devices, when proven successful, will serve as models for developing components and systems for new-millennium spacecraft.

  1. Approach to an Affordable and Sustainable Space Transportation System

    NASA Technical Reports Server (NTRS)

    McCleskey, Caey M.; Rhodes, R. E.; Robinson, J. W.; Henderson, E. M.

    2012-01-01

    This paper describes an approach and a general procedure for creating space transportation architectural concepts that are at once affordable and sustainable. Previous papers by the authors and other members of the Space Propulsion Synergy Team (SPST) focused on a functional system breakdown structure for an architecture and definition of high-payoff design techniques with a technology integration strategy. This paper follows up by using a structured process that derives architectural solutions focused on achieving life cycle affordability and sustainability. Further, the paper includes an example concept that integrates key design techniques discussed in previous papers. !

  2. Power Sources Focus Group - Evaluation of Plasma Gasification for Waste-to-Energy Conversion

    DTIC Science & Technology

    2012-09-21

    including paper , wood, plastic, food and agricultural waste. The system uses a shredder, dryer , and pelletizing preprocessor to fuel an in-house...limited information available, this paper does not attempt to determine the best way to use plasma in a gasifier. Instead, this paper makes general...Gasification Plasma gasification for the purposes of this paper includes any WTE system using plasma as part of the generation of syngas and/or cleanup

  3. Maturing Technologies for Stirling Space Power Generation

    NASA Technical Reports Server (NTRS)

    Wilson, Scott D.; Nowlin, Brentley C.; Dobbs, Michael W.; Schmitz, Paul C.; Huth, James

    2016-01-01

    Stirling Radioisotope Power Systems (RPS) are being developed as an option to provide power on future space science missions where robotic spacecraft will orbit, flyby, land or rove. A Stirling Radioisotope Generator (SRG) could offer space missions a more efficient power system that uses one fourth of the nuclear fuel and decreases the thermal footprint of the current state of the art. The RPS Program Office, working in collaboration with the U.S. Department of Energy (DOE), manages projects to develop thermoelectric and dynamic power systems, including Stirling Radioisotope Generators (SRGs). The Stirling Cycle Technology Development (SCTD) Project, located at Glenn Research Center (GRC), is developing Stirling-based subsystems, including convertors and controllers. The SCTD Project also performs research that focuses on a wide variety of objectives, including increasing convertor temperature capability to enable new environments, improving system reliability or fault tolerance, reducing mass or size, and developing advanced concepts that are mission enabling. Research activity includes maturing subsystems, assemblies, and components to prepare them for infusion into future convertor and generator designs. The status of several technology development efforts are described here. As part of the maturation process, technologies are assessed for readiness in higher-level subsystems. To assess the readiness level of the Dual Convertor Controller (DCC), a Technology Readiness Assessment (TRA) was performed and the process and results are shown. Stirling technology research is being performed by the SCTD Project for NASA's RPS Program Office, where tasks focus on maturation of Stirling-based systems and subsystems for future space science missions.

  4. Flat Terahertz Reflective Focusing Metasurface with Scanning Ability.

    PubMed

    Yi, Huan; Qu, Shi-Wei; Chen, Bao-Jie; Bai, Xue; Ng, Kung Bo; Chan, Chi Hou

    2017-06-14

    The ability to manipulate the propagation properties of electromagnetic waves, e.g., divergence, focusing, holography or deflection, is very significant in terahertz applications. Metasurfaces with flat structures are attractive for achieving such manipulations in terahertz band, as they feature low profile, lightweight, and ease of design and installation. Several types of terahertz reflective or transmitting metasurfaces with focusing function have been implemented recently, but none of them can provide scanning ability with controllable focus. Here, a flat reflective metasurface featuring controllable focal shift is proposed and experimentally demonstrated. Furthermore, the principle of designing a focus scanning reflective metasurface is presented and the focusing characteristics are discussed, including focus scanning along a line parallel or orthogonal to the metasurface with a large bandwidth. These interesting properties indicate that this flat reflective metasurface could play a key role in many terahertz imaging and detection systems.

  5. Systems fragility: The sociology of chaos.

    PubMed

    Hodges, Lori R

    2016-01-01

    This article examines the concept of community fragility in emergency management from a systems perspective. Using literature that addresses fragility in four areas of complex systems, including ecosystems, social systems, sociotechnical systems, and complex adaptive systems, a theoretical framework focused on the emergency management field is created. These findings illustrate how community fragility factors can be used in the emergency management field to not only improve overall outcomes after disaster but also build less fragile systems and communities in preparation for future disasters.

  6. Transforming user needs into functional requirements for an antibiotic clinical decision support system: explicating content analysis for system design.

    PubMed

    Bright, T J

    2013-01-01

    Many informatics studies use content analysis to generate functional requirements for system development. Explication of this translational process from qualitative data to functional requirements can strengthen the understanding and scientific rigor when applying content analysis in informatics studies. To describe a user-centered approach transforming emergent themes derived from focus group data into functional requirements for informatics solutions and to illustrate these methods to the development of an antibiotic clinical decision support system (CDS). THE APPROACH CONSISTED OF FIVE STEPS: 1) identify unmet therapeutic planning information needs via Focus Group Study-I, 2) develop a coding framework of therapeutic planning themes to refine the domain scope to antibiotic therapeutic planning, 3) identify functional requirements of an antibiotic CDS system via Focus Group Study-II, 4) discover informatics solutions and functional requirements from coded data, and 5) determine the types of information needed to support the antibiotic CDS system and link with the identified informatics solutions and functional requirements. The coding framework for Focus Group Study-I revealed unmet therapeutic planning needs. Twelve subthemes emerged and were clustered into four themes; analysis indicated a need for an antibiotic CDS intervention. Focus Group Study-II included five types of information needs. Comments from the Barrier/Challenge to information access and Function/Feature themes produced three informatics solutions and 13 functional requirements of an antibiotic CDS system. Comments from the Patient, Institution, and Domain themes generated required data elements for each informatics solution. This study presents one example explicating content analysis of focus group data and the analysis process to functional requirements from narrative data. Illustration of this 5-step method was used to develop an antibiotic CDS system, resolving unmet antibiotic prescribing needs. As a reusable approach, these techniques can be refined and applied to resolve unmet information needs with informatics interventions in additional domains.

  7. Arbitrary shaped, liquid filled reverberators with non-resonant transducers for broadband focusing of ultrasound using Time Reversed Acoustics.

    PubMed

    Sarvazyan, A; Fillinger, L

    2009-03-01

    The ability to generate short focused ultrasonic pulses with duration on the order of one period of carrier frequency depends on the bandwidth of the transmitter as the pulse duration is inversely proportional to the bandwidth. Conventional focusing arrays used for focusing ultrasound have limited bandwidth due to the resonant nature of the piezoelements generating ultrasound. Theoretically it is possible to build a broadband phased array composed of "non-resonant" elements: wedge-shaped or flat-concave piezotransducers, though there are numerous technical difficulties in designing arrays with hundreds of elements of complex shape. This task is much easier to realize in an alternative technique of ultrasound focusing based on the principles of Time Reversed Acoustics (TRA) because in TRA systems, effective focusing can be achieved with just a few, or even one, transducers. The goal of this study is to demonstrate the possibility of broadband focusing of ultrasonic waves using a TRA system with non-resonant transducers and to explore the factors affecting the performance of such a system. A new type of TRA reverberators, such as water-filled thin-wall plastic vessels, which can be used with the submersible piezotransducers fixed internally in the reverberator, are proposed and tested. The experiments are conducted in a water tank with the walls and bottom covered by a sound absorbing lining. A needle hydrophone mounted on a 3D positioning system is used as a beacon for the TRA focusing and then for measuring the spatial distribution of the focused ultrasound field. The bandwidth and spatial distribution of the signal focused by the TRA system using a single channel with the resonant versus non-resonant transducers have been analyzed. Two types of non-resonant transducers were tested: a flat-concave transducer with a diameter of 30 mm, and a thickness varying from 2 mm in the center to 11 mm at the edge, and a specially designed submersible transducer having an uneven shape with a diameter of about 25 mm and a thickness varying from 2 to 6 mm. It was shown that TRA focusing system using non-resonant transducer had a bandwidth at 10 dB of 500 kHz while the resonant transducer provided about 100 kHz bandwidth. Correspondingly, the extended bandwidth of the TRA focusing system, especially toward higher frequencies, provides a 50% sharper spatial distribution. Furthermore, the relative level of the background ultrasound was reduced by a factor up to 3 as more frequencies were added coherently in focus and incoherently out of focus. Advantages of water-filled reverberators made of thin-wall plastic vessels include easy manufacturing, low costs, extreme simplicity, and good acoustical matching with soft tissues, important for biomedical applications.

  8. Data model for the collaboration between land administration systems and agricultural land parcel identification systems.

    PubMed

    Inan, Halil Ibrahim; Sagris, Valentina; Devos, Wim; Milenov, Pavel; van Oosterom, Peter; Zevenbergen, Jaap

    2010-12-01

    The Common Agricultural Policy (CAP) of the European Union (EU) has dramatically changed after 1992, and from then on the CAP focused on the management of direct income subsidies instead of production-based subsidies. For this focus, Member States (MS) are expected to establish Integrated Administration and Control System (IACS), including a Land Parcel Identification System (LPIS) as the spatial part of IACS. Different MS have chosen different solutions for their LPIS. Currently, some MS based their IACS/LPIS on data from their Land Administration Systems (LAS), and many others use purpose built special systems for their IACS/LPIS. The issue with these different IACS/LPIS is that they do not have standardized structures; rather, each represents a unique design in each MS, both in the case of LAS based or special systems. In this study, we aim at designing a core data model for those IACS/LPIS based on LAS. For this purpose, we make use of the ongoing standardization initiatives for LAS (Land Administration Domain Model: LADM) and IACS/LPIS (LPIS Core Model: LCM). The data model we propose in this study implies the collaboration between LADM and LCM and includes some extensions. Some basic issues with the collaboration model are discussed within this study: registration of farmers, land use rights and farming limitations, geometry/topology, temporal data management etc. For further explanation of the model structure, sample instance level diagrams illustrating some typical situations are also included. Copyright © 2010 Elsevier Ltd. All rights reserved.

  9. 77 FR 75612 - New England Fishery Management Council; Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-21

    ..., focusing on the section pertaining to modifications to the current days-at-sea (DAS) trip limit management system, including alternatives for establishing a monkfish DAS leasing program. The recommendations of...

  10. 77 FR 42699 - New England Fishery Management Council; Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-20

    ... such, this meeting will focus on potential modifications to the current days-at-sea (DAS) management system, including alternatives to enable DAS leasing, and on approaches to integrate monkfish into the...

  11. NASA Tech Briefs, June 2002. Volume 26, No. 6

    NASA Technical Reports Server (NTRS)

    2002-01-01

    Topics include: a technology focus on data acquisition, electronic components and systems, software, materials, mechanics, machinery/automation, physical sciences, book and reports, motion control, and a special section of Photonics Tech Briefs.

  12. Qualifications of drivers - vision and diabetes

    DOT National Transportation Integrated Search

    2011-01-01

    San Francisco UPA projects focus on reducing traffic congestion related to parking in downtown San Francisco. Intelligent transportation systems (ITS) technologies underlie many of the San Francisco UPA projects, including parking and roadway sensors...

  13. NASA Tech Briefs, September 2002. Volume 26, No. 9

    NASA Technical Reports Server (NTRS)

    2002-01-01

    Topics include: a technology focus on data acquisition, electronic components and systems, software, materials, mechanics, machinery/automation, bio-medical, physical sciences, book and reports, and a special section of Photonics Tech Briefs.

  14. Distributed and grid computing projects with research focus in human health.

    PubMed

    Diomidous, Marianna; Zikos, Dimitrios

    2012-01-01

    Distributed systems and grid computing systems are used to connect several computers to obtain a higher level of performance, in order to solve a problem. During the last decade, projects use the World Wide Web to aggregate individuals' CPU power for research purposes. This paper presents the existing active large scale distributed and grid computing projects with research focus in human health. There have been found and presented 11 active projects with more than 2000 Processing Units (PUs) each. The research focus for most of them is molecular biology and, specifically on understanding or predicting protein structure through simulation, comparing proteins, genomic analysis for disease provoking genes and drug design. Though not in all cases explicitly stated, common target diseases include research to find cure against HIV, dengue, Duchene dystrophy, Parkinson's disease, various types of cancer and influenza. Other diseases include malaria, anthrax, Alzheimer's disease. The need for national initiatives and European Collaboration for larger scale projects is stressed, to raise the awareness of citizens to participate in order to create a culture of internet volunteering altruism.

  15. Focusing on the Formative: Building an Assessment System Aimed at Student Growth and Development.

    PubMed

    Konopasek, Lyuba; Norcini, John; Krupat, Edward

    2016-11-01

    This Perspective addresses the need for an integrated system of formative and summative assessment in undergraduate medical education with a focus on the formative. While acknowledging the importance of summative assessment, which asks whether trainees have met criteria for progression, the authors propose that a formatively focused assessment system can best accomplish a central task of competency-based medical education: transmitting feedback to learners in a format and a manner that will help them to improve, develop, and grow. Formative assessment should not be seen as a set of singular events but, rather, as a process that is organized and integrated over time, much like the cycle of quality improvement in medicine. To justify this position, the authors discuss its conceptual underpinnings and rationale, including the need to prepare learners for the formatively focused assessment system of graduate medical education. Next, the authors identify assessment strategies that could be employed, as well as the characteristics of an institutional culture and the learner-teacher relationship necessary for a learner-centered, improvement-focused assessment system to succeed. Finally, an infrastructure for such a system is proposed. This consists of a foundation of well-articulated and disseminated milestones for achievement and four pillars: faculty development, learner development, longitudinal academic advising and coaching, and documentation of developing competence. The authors conclude by suggesting that the guidelines proposed are analogous to the principles of continuity and coordination of care, so much valued in the world of medicine yet often overlooked in the world of education.

  16. Mechanisms & Other Systems. Stuff That Works! A Technology Curriculum for the Elementary Grades.

    ERIC Educational Resources Information Center

    Benenson, Gary

    This book focuses on devices and systems that transform motion or convert energy. Contents are divided into six chapters: (1) "Appetizers" includes activities that can be done individually to become familiar with the topic of machines and mechanisms; (2) "Concepts" provides a basis for machine and mechanism development; (3)…

  17. Computer-Aided College Algebra: Learning Components that Students Find Beneficial

    ERIC Educational Resources Information Center

    Aichele, Douglas B.; Francisco, Cynthia; Utley, Juliana; Wescoatt, Benjamin

    2011-01-01

    A mixed-method study was conducted during the Fall 2008 semester to better understand the experiences of students participating in computer-aided instruction of College Algebra using the software MyMathLab. The learning environment included a computer learning system for the majority of the instruction, a support system via focus groups (weekly…

  18. Organization of Distance Education at the University of Zambia: An Analysis of the Practice.

    ERIC Educational Resources Information Center

    Nyirenda, Juma E.

    1989-01-01

    Discussion of two basic organizational models for distance education systems or institutions focuses on the mixed-mode organization at the University of Zambia. Highlights include the development, production, storage, and distribution of teaching materials; communication channels between students and teachers; and the record-keeping system. (11…

  19. Educational Policy Issues for the 1990s: Balancing Equity and Excellence in Implementing the Reform Agenda.

    ERIC Educational Resources Information Center

    Marcoulides, George A.; Heck, Ronald H.

    1990-01-01

    Discusses problems with reform issues that focus specifically on changing the system of educational policymaking to achieve excellence but lack safeguards against compromising equality of educational opportunity in the public school system. Explores the conflicting political views of reform policy, which include economic issues and democratic…

  20. Collapse of Monopoly Privilege: From College to University

    ERIC Educational Resources Information Center

    Davidovitch, Nitza; Soen, Dan; Iram, Yaacov

    2008-01-01

    This article focuses on the erosion of the monopoly by universities of the higher education system in Israel. The hegemony of the universities, the major player in the academic field, has been shattered by the development of the regional colleges that unsettled the preconceptions concerning the higher education system in Israel, including the…

  1. Teacher's Guide to Accompany "Artes Latinae," the Encyclopaedia Britannica Latin Instructional System.

    ERIC Educational Resources Information Center

    Masciantonio, Rudolph; And Others

    This guide, a supplement to the "Artes Latinae Level One Teacher's Manual," prepared for use in the School District of Philadelphia, focuses primarily on how to adapt this course, intended for individualized instruction, to group instruction. Discussion of the multisensory instructional system includes remarks concerning the use of films, study…

  2. Variable magnification variable dispersion glancing incidence imaging x-ray spectroscopic telescope

    NASA Technical Reports Server (NTRS)

    Hoover, Richard B. (Inventor)

    1991-01-01

    A variable magnification variable dispersion glancing incidence x-ray spectroscopic telescope capable of multiple high spatial revolution imaging at precise spectral lines of solar and stellar x-ray and extreme ultraviolet radiation sources includes a pirmary optical system which focuses the incoming radiation to a primary focus. Two or more rotatable carries each providing a different magnification are positioned behind the primary focus at an inclination to the optical axis, each carrier carrying a series of ellipsoidal diffraction grating mirrors each having a concave surface on which the gratings are ruled and coated with a mutlilayer coating to reflect by diffraction a different desired wavelength. The diffraction grating mirrors of both carriers are segments of ellipsoids having a common first focus coincident with the primary focus. A contoured detector such as an x-ray sensitive photogrpahic film is positioned at the second respective focus of each diffraction grating so that each grating may reflect the image at the first focus to the detector at the second focus. The carriers are selectively rotated to position a selected mirror for receiving radiation from the primary optical system, and at least the first carrier may be withdrawn from the path of the radiation to permit a selected grating on the second carrier to receive radiation.

  3. Variable magnification variable dispersion glancing incidence imaging x ray spectroscopic telescope

    NASA Technical Reports Server (NTRS)

    Hoover, Richard (Inventor)

    1990-01-01

    A variable magnification variable dispersion glancing incidence x ray spectroscopic telescope capable of multiple high spatial revolution imaging at precise spectral lines of solar and stellar x ray and extreme ultraviolet radiation sources includes a primary optical system which focuses the incoming radiation to a primary focus. Two or more rotatable carriers each providing a different magnification are positioned behind the primary focus at an inclination to the optical axis, each carrier carrying a series of ellipsoidal diffraction grating mirrors each having a concave surface on which the gratings are ruled and coated with a multilayer coating to reflect by diffraction a different desired wavelength. The diffraction grating mirrors of both carriers are segments of ellipsoids having a common first focus coincident with the primary focus. A contoured detector such as an x ray sensitive photographic film is positioned at the second respective focus of each diffraction grating so that each grating may reflect the image at the first focus to the detector at the second focus. The carriers are selectively rotated to position a selected mirror for receiving radiation from the primary optical system, and at least the first carrier may be withdrawn from the path of the radiation to permit a selected grating on the second carrier to receive radiation.

  4. Towards public health decision support: a systematic review of bidirectional communication approaches.

    PubMed

    Dixon, Brian E; Gamache, Roland E; Grannis, Shaun J

    2013-05-01

    To summarize the literature describing computer-based interventions aimed at improving bidirectional communication between clinical and public health. A systematic review of English articles using MEDLINE and Google Scholar. Search terms included public health, epidemiology, electronic health records, decision support, expert systems, and decision-making. Only articles that described the communication of information regarding emerging health threats from public health agencies to clinicians or provider organizations were included. Each article was independently reviewed by two authors. Ten peer-reviewed articles highlight a nascent but promising area of research and practice related to alerting clinicians about emerging threats. Current literature suggests that additional research and development in bidirectional communication infrastructure should focus on defining a coherent architecture, improving interoperability, establishing clear governance, and creating usable systems that will effectively deliver targeted, specific information to clinicians in support of patient and population decision-making. Increasingly available clinical information systems make it possible to deliver timely, relevant knowledge to frontline clinicians in support of population health. Future work should focus on developing a flexible, interoperable infrastructure for bidirectional communications capable of integrating public health knowledge into clinical systems and workflows.

  5. Report on all ARRA Funded Technical Work

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None, None

    2013-10-05

    The main focus of this American Recovery and Reinvestment Act of 2009 (ARRA) funded project was to design an energy efficient carbon capture and storage (CCS) process using the Recipients membrane system for H{sub 2} separation and CO{sub 2} capture. In the ARRA-funded project, the Recipient accelerated development and scale-up of ongoing hydrogen membrane technology research and development (R&D). Specifically, this project focused on accelerating the current R&D work scope of the base program-funded project, involving lab scale tests, detail design of a 250 lb/day H{sub 2} process development unit (PDU), and scale-up of membrane tube and coating manufacturing. Thismore » project scope included the site selection and a Front End Engineering Design (FEED) study of a nominally 4 to 10 ton-per-day (TPD) Pre-Commercial Module (PCM) hydrogen separation membrane system. Process models and techno-economic analysis were updated to include studies on integration of this technology into an Integrated Gasification Combined Cycle (IGCC) power generation system with CCS.« less

  6. Metal Ion Modeling Using Classical Mechanics

    PubMed Central

    2017-01-01

    Metal ions play significant roles in numerous fields including chemistry, geochemistry, biochemistry, and materials science. With computational tools increasingly becoming important in chemical research, methods have emerged to effectively face the challenge of modeling metal ions in the gas, aqueous, and solid phases. Herein, we review both quantum and classical modeling strategies for metal ion-containing systems that have been developed over the past few decades. This Review focuses on classical metal ion modeling based on unpolarized models (including the nonbonded, bonded, cationic dummy atom, and combined models), polarizable models (e.g., the fluctuating charge, Drude oscillator, and the induced dipole models), the angular overlap model, and valence bond-based models. Quantum mechanical studies of metal ion-containing systems at the semiempirical, ab initio, and density functional levels of theory are reviewed as well with a particular focus on how these methods inform classical modeling efforts. Finally, conclusions and future prospects and directions are offered that will further enhance the classical modeling of metal ion-containing systems. PMID:28045509

  7. Nanosilver: new ageless and versatile biomedical therapeutic scaffold

    PubMed Central

    Ullah Khan, Shahid; Khan, Muhammad Hafeez Ullah; Khan, Dilfaraz; Ullah Khan, Wasim; Rahim, Abdur; Kamal, Sajid; Ullah Khan, Farman; Fahad, Shah

    2018-01-01

    Silver nanotechnology has received tremendous attention in recent years, owing to its wide range of applications in various fields and its intrinsic therapeutic properties. In this review, an attempt is made to critically evaluate the chemical, physical, and biological synthesis of silver nanoparticles (AgNPs) as well as their efficacy in the field of theranostics including microbiology and parasitology. Moreover, an outlook is also provided regarding the performance of AgNPs against different biological systems such as bacteria, fungi, viruses, and parasites (leishmanial and malarial parasites) in curing certain fatal human diseases, with a special focus on cancer. The mechanism of action of AgNPs in different biological systems still remains enigmatic. Here, due to limited available literature, we only focused on AgNPs mechanism in biological systems including human (wound healing and apoptosis), bacteria, and viruses which may open new windows for future research to ensure the versatile application of AgNPs in cosmetics, electronics, and medical fields. PMID:29440898

  8. Comparison of Detector Technologies for CAPS

    NASA Technical Reports Server (NTRS)

    Stockum, Jana L.

    2005-01-01

    In this paper, several different detectors are examined for use in a Comet/Asteroid Protection System (CAPS), a conceptual study for a possible future space-based system. Each detector will be examined for its future (25 years or more in the future) ability to find and track near-Earth Objects (NEOs) from a space-based detection platform. Within the CAPS study are several teams of people who each focus on different aspects of the system concept. This study s focus is on detection devices. In particular, evaluations on the following devices have been made: charge-coupled devices (CCDs), charge-injected devices (CIDs), superconducting tunneling junctions (STJs), and transition edge sensors (TESs). These devices can be separated into two main categories; the first category includes detectors that are currently being widely utilized, such as CCDs and CIDs. The second category includes experimental detectors, such as STJs and TESs. After the discussion of the detectors themselves, there will be a section devoted to the explicit use of these detectors with CAPS.

  9. Development of Structural Health Management Technology for Aerospace Vehicles

    NASA Technical Reports Server (NTRS)

    Prosser, W. H.

    2003-01-01

    As part of the overall goal of developing Integrated Vehicle Health Management (IVHM) systems for aerospace vehicles, NASA has focused considerable resources on the development of technologies for Structural Health Management (SHM). The motivations for these efforts are to increase the safety and reliability of aerospace structural systems, while at the same time decreasing operating and maintenance costs. Research and development of SHM technologies has been supported under a variety of programs for both aircraft and spacecraft including the Space Launch Initiative, X-33, Next Generation Launch Technology, and Aviation Safety Program. The major focus of much of the research to date has been on the development and testing of sensor technologies. A wide range of sensor technologies are under consideration including fiber-optic sensors, active and passive acoustic sensors, electromagnetic sensors, wireless sensing systems, MEMS, and nanosensors. Because of their numerous advantages for aerospace applications, most notably being extremely light weight, fiber-optic sensors are one of the leading candidates and have received considerable attention.

  10. Computerized tomography calibrator

    NASA Technical Reports Server (NTRS)

    Engel, Herbert P. (Inventor)

    1991-01-01

    A set of interchangeable pieces comprising a computerized tomography calibrator, and a method of use thereof, permits focusing of a computerized tomographic (CT) system. The interchangeable pieces include a plurality of nestable, generally planar mother rings, adapted for the receipt of planar inserts of predetermined sizes, and of predetermined material densities. The inserts further define openings therein for receipt of plural sub-inserts. All pieces are of known sizes and densities, permitting the assembling of different configurations of materials of known sizes and combinations of densities, for calibration (i.e., focusing) of a computerized tomographic system through variation of operating variables thereof. Rather than serving as a phanton, which is intended to be representative of a particular workpiece to be tested, the set of interchangeable pieces permits simple and easy standardized calibration of a CT system. The calibrator and its related method of use further includes use of air or of particular fluids for filling various openings, as part of a selected configuration of the set of pieces.

  11. On Robust Methodologies for Managing Public Health Care Systems

    PubMed Central

    Nimmagadda, Shastri L.; Dreher, Heinz V.

    2014-01-01

    Authors focus on ontology-based multidimensional data warehousing and mining methodologies, addressing various issues on organizing, reporting and documenting diabetic cases and their associated ailments, including causalities. Map and other diagnostic data views, depicting similarity and comparison of attributes, extracted from warehouses, are used for understanding the ailments, based on gender, age, geography, food-habits and other hereditary event attributes. In addition to rigor on data mining and visualization, an added focus is on values of interpretation of data views, from processed full-bodied diagnosis, subsequent prescription and appropriate medications. The proposed methodology, is a robust back-end application, for web-based patient-doctor consultations and e-Health care management systems through which, billions of dollars spent on medical services, can be saved, in addition to improving quality of life and average life span of a person. Government health departments and agencies, private and government medical practitioners including social welfare organizations are typical users of these systems. PMID:24445953

  12. Library Functions, Scholarly Communication, and the Foundation of the Digital Library: Laying Claim to the Control Zone.

    ERIC Educational Resources Information Center

    Atkinson, Ross

    1996-01-01

    Discussion of academic libraries and online systems focuses on core library services and a digital library which could serve as an alternative publishing mechanism for specialized scholarly communication. Highlights include adding value to sources of information; conflicts, including those with commercial publishers; and standardization and…

  13. Document Image Processing: Going beyond the Black-and-White Barrier. Progress, Issues and Options with Greyscale and Colour Image Processing.

    ERIC Educational Resources Information Center

    Hendley, Tom

    1995-01-01

    Discussion of digital document image processing focuses on issues and options associated with greyscale and color image processing. Topics include speed; size of original document; scanning resolution; markets for different categories of scanners, including photographic libraries, publishing, and office applications; hybrid systems; data…

  14. Mexico Higher Education. Reviews of National Policies for Education.

    ERIC Educational Resources Information Center

    Organisation for Economic Cooperation and Development, Paris (France).

    This review focuses on higher education in Mexico and also covers the upper secondary level including the broader range of education and training courses and institutions for students who complete basic education. Part 1 provides background data on Mexico and its system of higher education. Chapter 1 includes a general description of Mexico today…

  15. Optics: Light, Color, and Their Uses. An Educator's Guide With Activities In Science and Mathematics

    NASA Technical Reports Server (NTRS)

    2000-01-01

    This document includes information on the Chandra X-Ray Observatory, the Hubble Space Telescope, the Next Generation Space Telescope, Soft X-Ray Imager, and the Lightning Imaging System. Classroom activities from grades K-12 are included, focusing on light and color, using mirrors, lenses, prisms, and filters.

  16. Trajectory Optimization for Missions to Small Bodies with a Focus on Scientific Merit.

    PubMed

    Englander, Jacob A; Vavrina, Matthew A; Lim, Lucy F; McFadden, Lucy A; Rhoden, Alyssa R; Noll, Keith S

    2017-01-01

    Trajectory design for missions to small bodies is tightly coupled both with the selection of targets for a mission and with the choice of spacecraft power, propulsion, and other hardware. Traditional methods of trajectory optimization have focused on finding the optimal trajectory for an a priori selection of destinations and spacecraft parameters. Recent research has expanded the field of trajectory optimization to multidisciplinary systems optimization that includes spacecraft parameters. The logical next step is to extend the optimization process to include target selection based not only on engineering figures of merit but also scientific value. This paper presents a new technique to solve the multidisciplinary mission optimization problem for small-bodies missions, including classical trajectory design, the choice of spacecraft power and propulsion systems, and also the scientific value of the targets. This technique, when combined with modern parallel computers, enables a holistic view of the small body mission design process that previously required iteration among several different design processes.

  17. Marine Corps Systems Command (MCSC) Advanced Planning Briefing To Industry (APBI)

    DTIC Science & Technology

    2008-05-14

    High force protection bill associated with establishing and maintaining a secure lodgment – Ships densely packed, assemble ashore • MPF(F) – Operates...14 May 08 EXPEDITIONARY FIGHTING VEHICLE (EFV) Provide High Speed Transport of Embarked Marine Infantry From Ships Located Beyond the Horizon to...Business Size Crafting your RFI Response DO - Focus exclusively on Past Performance Provide a “Team” Brief Focus on “non-Priorities” Include

  18. Rocket Design for the Future

    NASA Technical Reports Server (NTRS)

    Follett, William W.; Rajagopal, Raj

    2001-01-01

    The focus of the AA MDO team is to reduce product development cost through the capture and automation of best design and analysis practices and through increasing the availability of low-cost, high-fidelity analysis. Implementation of robust designs reduces costs associated with the Test-Fall-Fix cycle. RD is currently focusing on several technologies to improve the design process, including optimization and robust design, expert and rule-based systems, and collaborative technologies.

  19. Precision Attitude Determination System (PADS) design and analysis. Two-axis gimbal star tracker

    NASA Technical Reports Server (NTRS)

    1973-01-01

    Development of the Precision Attitude Determination System (PADS) focused chiefly on the two-axis gimballed star tracker and electronics design improved from that of Precision Pointing Control System (PPCS), and application of the improved tracker for PADS at geosynchronous altitude. System design, system analysis, software design, and hardware design activities are reported. The system design encompasses the PADS configuration, system performance characteristics, component design summaries, and interface considerations. The PADS design and performance analysis includes error analysis, performance analysis via attitude determination simulation, and star tracker servo design analysis. The design of the star tracker and electronics are discussed. Sensor electronics schematics are included. A detailed characterization of the application software algorithms and computer requirements is provided.

  20. An Exploratory Study on How Primary Pupils Approach Systems

    ERIC Educational Resources Information Center

    Koski, Marja-Ilona; de Vries, Marc

    2013-01-01

    This paper presents a study of systems thinking among 27 primary pupils (8-10 years old) and their teacher. The study included a pre-test for the teacher and the pupils, lesson planning, the actual lesson and a post-test for the pupils. The research focused on finding an answer to three questions: (1) do pupils see a system as a structure…

  1. Development and Application of an Integrated Approach toward NASA Airspace Systems Research

    NASA Technical Reports Server (NTRS)

    Barhydt, Richard; Fong, Robert K.; Abramson, Paul D.; Koenke, Ed

    2008-01-01

    The National Aeronautics and Space Administration's (NASA) Airspace Systems Program is contributing air traffic management research in support of the 2025 Next Generation Air Transportation System (NextGen). Contributions support research and development needs provided by the interagency Joint Planning and Development Office (JPDO). These needs generally call for integrated technical solutions that improve system-level performance and work effectively across multiple domains and planning time horizons. In response, the Airspace Systems Program is pursuing an integrated research approach and has adapted systems engineering best practices for application in a research environment. Systems engineering methods aim to enable researchers to methodically compare different technical approaches, consider system-level performance, and develop compatible solutions. Systems engineering activities are performed iteratively as the research matures. Products of this approach include a demand and needs analysis, system-level descriptions focusing on NASA research contributions, system assessment and design studies, and common systemlevel metrics, scenarios, and assumptions. Results from the first systems engineering iteration include a preliminary demand and needs analysis; a functional modeling tool; and initial system-level metrics, scenario characteristics, and assumptions. Demand and needs analysis results suggest that several advanced concepts can mitigate demand/capacity imbalances for NextGen, but fall short of enabling three-times current-day capacity at the nation s busiest airports and airspace. Current activities are focusing on standardizing metrics, scenarios, and assumptions, conducting system-level performance assessments of integrated research solutions, and exploring key system design interfaces.

  2. [Combined forecasting system of peritonitis outcome].

    PubMed

    Lebedev, N V; Klimov, A E; Agrba, S B; Gaidukevich, E K

    To create a reliable system for assessing of severity and prediction of the outcome of peritonitis. Critical analysis of the systems for peritonitis severity assessment is presented. The study included outcomes of 347 patients who admitted at the Department of Faculty Surgery of Peoples' Friendship University of Russia in 2015-2016. The cause of peritonitis were destructive forms of acute appendicitis, cholecystitis, perforated gastroduodenal ulcer, various perforation of small and large intestines (including tumor). Combined forecasting system for peritonitis severity assessment is created. The system includes clinical, laboratory data, assessment of systemic inflammatory response (SIRS) and severity of organ failure (qSOFA). The authors focused on easily identifiable parameters which are available in virtually any surgical hospital. Threshold value (lethal outcome probability over 50%) is 8 scores in this system. Sensitivity, specificity and accuracy were 93.3, 99.7 and 98.9%, respectively according to ROC-curve that exceeds those parameters of MPI and APACHE II.

  3. Applications of artificial intelligence V; Proceedings of the Meeting, Orlando, FL, May 18-20, 1987

    NASA Technical Reports Server (NTRS)

    Gilmore, John F. (Editor)

    1987-01-01

    The papers contained in this volume focus on current trends in applications of artificial intelligence. Topics discussed include expert systems, image understanding, artificial intelligence tools, knowledge-based systems, heuristic systems, manufacturing applications, and image analysis. Papers are presented on expert system issues in automated, autonomous space vehicle rendezvous; traditional versus rule-based programming techniques; applications to the control of optional flight information; methodology for evaluating knowledge-based systems; and real-time advisory system for airborne early warning.

  4. C2-Related Incidents Reported by UAS Pilots

    NASA Technical Reports Server (NTRS)

    Hobbs, Alan; Cardoza, Colleen; Null, Cynthia

    2016-01-01

    It has been estimated that aviation accidents are typically preceded by numerous minor incidents arising from the same causal factors that ultimately produced the accident. Accident databases provide in-depth information on a relatively small number of occurrences, however incident databases have the potential to provide insights into the human factors of Remotely Piloted Aircraft System (RPAS) operations based on a larger volume of less-detailed reports. Currently, there is a lack of incident data dealing with the human factors of unmanned aircraft systems. An exploratory study is being conducted to examine the feasibility of collecting voluntary critical incident reports from RPAS pilots. Twenty-three experienced RPAS pilots volunteered to participate in focus groups in which they described critical incidents from their own experience. Participants were asked to recall (1) incidents that revealed a system flaw, or (2) highlighted a case where the human operator contributed to system resilience or mission success. Participants were asked to only report incidents that could be included in a public document. During each focus group session, a note taker produced a de-identified written record of the incident narratives. At the end of the session, participants reviewed each written incident report, and made edits and corrections as necessary. The incidents were later analyzed to identify contributing factors, with a focus on design issues that either hindered or assisted the pilot during the events. A total of 90 incidents were reported. This presentation focuses on incidents that involved the management of the command and control (C2) link. The identified issues include loss of link, interference from undesired transmissions, voice latency, accidental control transfer, and the use of the lost link timer, or lost link OK features.

  5. Uncertainty Analysis of Seebeck Coefficient and Electrical Resistivity Characterization

    NASA Technical Reports Server (NTRS)

    Mackey, Jon; Sehirlioglu, Alp; Dynys, Fred

    2014-01-01

    In order to provide a complete description of a materials thermoelectric power factor, in addition to the measured nominal value, an uncertainty interval is required. The uncertainty may contain sources of measurement error including systematic bias error and precision error of a statistical nature. The work focuses specifically on the popular ZEM-3 (Ulvac Technologies) measurement system, but the methods apply to any measurement system. The analysis accounts for sources of systematic error including sample preparation tolerance, measurement probe placement, thermocouple cold-finger effect, and measurement parameters; in addition to including uncertainty of a statistical nature. Complete uncertainty analysis of a measurement system allows for more reliable comparison of measurement data between laboratories.

  6. Can ICTs contribute to the efficiency and provide equitable access to the health care system in Sub-Saharan Africa? The Mali experience.

    PubMed

    Bagayoko, C O; Anne, A; Fieschi, M; Geissbuhler, A

    2011-01-01

    The aim of this study is to demonstrate from actual projects that ICT can contribute to the balance of health systems in developing countries and to equitable access to human resources and quality health care service. Our study is focused on two essential elements which are: i) Capacity building and support of health professionals, especially those in isolated areas using telemedicine tools; ii) Strengthening of hospital information systems by taking advantage of full potential offered by open-source software. Our research was performed on the activities carried out in Mali and in part through the RAFT (Réseau en Afrique Francophone pour la Télémédecine) Network. We focused mainly on the activities of e-learning, telemedicine, and hospital information systems. These include the use of platforms that work with low Internet connection bandwidth. With regard to information systems, our strategy is mainly focused on the improvement and implementation of open-source tools. Several telemedicine application projects were reviewed including continuing online medical education and the support of isolated health professionals through the usage of innovative tools. This review covers the RAFT project for continuing medical education in French-speaking Africa, the tele-radiology project in Mali, the "EQUI-ResHuS" project for equal access to health over ICT in Mali, The "Pact-e.Santé" project for community health workers in Mali. We also detailed a large-scale experience of an open-source hospital information system implemented in Mali: "Cinz@n". We report on successful experiences in the field of telemedicine and on the evaluation by the end-users of the Cinz@n project, a pilot hospital information system in Mali. These reflect the potential of healthcare-ICT for Sub-Saharan African countries.

  7. Patient and provider perspectives on the design and implementation of an electronic consultation system for kidney care delivery in Canada: a focus group study.

    PubMed

    Bello, Aminu K; Molzahn, Anita E; Girard, Louis P; Osman, Mohamed A; Okpechi, Ikechi G; Glassford, Jodi; Thompson, Stephanie; Keely, Erin; Liddy, Clare; Manns, Braden; Jinda, Kailash; Klarenbach, Scott; Hemmelgarn, Brenda; Tonelli, Marcello

    2017-03-02

    We assessed stakeholder perceptions on the use of an electronic consultation system (e-Consult) to improve the delivery of kidney care in Alberta. We aim to identify acceptability, barriers and facilitators to the use of an e-Consult system for ambulatory kidney care delivery. This was a qualitative focus group study using a thematic analysis design. Eight focus groups were held in four locations in the province of Alberta, Canada. In total, there were 72 participants in two broad stakeholder categories: patients (including patients' relatives) and providers (including primary care physicians, nephrologists, other care providers and policymakers). The e-Consult system was generally acceptable across all stakeholder groups. The key barriers identified were length of time required for referring physicians to complete the e-Consult due to lack of integration with current electronic medical records, and concerns that increased numbers of requests might overwhelm nephrologists and lead to a delayed response or an unsustainable system. The key facilitators identified were potential improvement of care coordination, dissemination of best practice through an educational platform, comprehensive data to make decisions without the need for face-to-face consultation, timely feedback to primary care providers, timeliness/reduced delays for patients' rapid triage and identification of cases needing urgent care and improved access to information to facilitate decision-making in patient care. Stakeholder perceptions regarding the e-Consult system were favourable, and the key barriers and facilitators identified will be considered in design and implementation of an acceptable and sustainable electronic consultation system for kidney care delivery. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  8. Addressing overuse of health services in health systems: a critical interpretive synthesis.

    PubMed

    Ellen, Moriah E; Wilson, Michael G; Vélez, Marcela; Shach, Ruth; Lavis, John N; Grimshaw, Jeremy M; Moat, Kaelan A

    2018-06-15

    Health systems are increasingly focusing on the issue of 'overuse' of health services and how to address it. We developed a framework focused on (1) the rationale and context for health systems prioritising addressing overuse, (2) elements of a comprehensive process and approach to reduce overuse and (3) implementation considerations for addressing overuse. We conducted a critical interpretive synthesis informed by a stakeholder-engagement process. The synthesis identified relevant empirical and non-empirical articles about system-level overuse. Two reviewers independently screened records, assessed for inclusion and conceptually mapped included articles. From these, we selected a purposive sample, created structured summaries of key findings and thematically synthesised the results. Our search identified 3545 references, from which we included 251. Most articles (76%; n = 192) were published within 5 years of conducting the review and addressed processes for addressing overuse (63%; n = 158) or political and health system context (60%; n = 151). Besides negative outcomes at the patient, system and global level, there were various contextual factors to addressing service overuse that seem to be key issue drivers. Processes for addressing overuse can be grouped into three elements comprising a comprehensive approach, including (1) approaches to identify overused health services, (2) stakeholder- or patient-led approaches and (3) government-led initiatives. Key implementation considerations include the need to develop 'buy in' from stakeholders and citizens. Health systems want to ensure the use of high-value services to keep citizens healthy and avoid harm. Our synthesis can be used by policy-makers, stakeholders and researchers to understand how the issue has been prioritised, what approaches have been used to address it and implementation considerations. PROSPERO CRD42014013204 .

  9. Alzheimer's disease and the law: positive and negative consequences of structural stigma and labeling in the legal system.

    PubMed

    Werner, Perla; Doron, Israel Issi

    2017-11-01

    To explore the meaning and consequences of labeling on structural stigma in the context of Alzheimer's disease (AD) in the legal system. This qualitative study was made up of three focus groups including social workers and lawyers (n = 26). Participants were asked to report their experience in circumstances in which persons with AD and their family members engage with the legal system. Thematic analysis using the constant comparative method was used. The discussions in the focus groups raised two overall themes. (1) The significance of the medical diagnostic labeling of AD in the legal system and (2) the consequences of labeling of AD within the legal system. This last theme included four sub-themes: (a) negative consequences of labeling; (b) reasons associated with negative consequences of labeling; (c) positive consequences of labeling; and (d) reasons associated with positive consequences of labeling. Findings of the study provide a first foundation for future research on the meaning and consequences of labeling in legal cases involving persons with AD. They suggest that increasing judges' knowledge about AD and reforming the existing 'status-based' legal capacity legislation might benefit by limiting the legal weight given today to the medical diagnosis.

  10. Radiation Requirements and Requirements Flowdown: Single Event Effects (SEEs) and Requirements

    NASA Technical Reports Server (NTRS)

    LaBel, Kenneth A.

    2002-01-01

    This short course session provides: (1) an overview of the single particle-induced hazard for space system as they apply in the natural space environment. This shall focus on the implementation of a single event effect hardness assurance (SEEHA) program for systems including system engineering approach and mitigation of effects. (2) The final portion of this session shell provide relevant real-life examples of in-flight performance of systems.

  11. Nanoparticles functionalized with supramolecular host-guest systems for nanomedicine and healthcare.

    PubMed

    Wu, Zilong; Song, Nan; Menz, Ryan; Pingali, Bharadwaj; Yang, Ying-Wei; Zheng, Yuebing

    2015-05-01

    Synthetic macrocyclic host compounds can interact with suitable guest molecules via noncovalent interactions to form functional supramolecular systems. With the synergistic integration of the response of molecules and the unique properties at the nanoscale, nanoparticles functionalized with the host-guest supramolecular systems have shown great potentials for a broad range of applications in the fields of nanoscience and nanotechnology. In this review article, we focus on the applications of the nanoparticles functionalized with supramolecular host-guest systems in nanomedicine and healthcare, including therapeutic delivery, imaging, sensing and removal of harmful substances. A large number of examples are included to elucidate the working mechanisms, advantages, limitations and future developments of the nanoparticle-supramolecule systems in these applications.

  12. The deepening crisis in U.S. health care: a review of data.

    PubMed

    Hellander, Ida

    2011-01-01

    This report presents information on the state of the U.S. health system in 2010. It includes data on the uninsured and underinsured and their access to health care, on socioeconomic inequality in health care, and on the rising costs of the U.S. health system. It also presents information on the role of corporate money in health care, focusing on the pharmaceutical industry, Medicare HMOs, and corporate-government conflicts of interest. The author includes results from public opinion polls on health system reform and recent data on international health systems and international system comparisons. The article concludes with an update on the U.S. federal health reform legislation.

  13. Polymers in separation processes

    NASA Astrophysics Data System (ADS)

    Wieszczycka, Karolina; Staszak, Katarzyna

    2017-05-01

    Application of polymer materials as membranes and ion-exchange resins was presented with a focus on their use for the recovery of metal ions from aqueous solutions. Several membrane techniques were described including reverse osmosis, nanofiltration, ultrafiltration, diffusion and Donnan dialysis, electrodialysis and membrane extraction system (polymer inclusion and supported membranes). Moreover, the examples of using ion-exchange resins in metal recovery were presented. The possibility of modification of the resin was discussed, including hybrid system with metal cation or metal oxide immobilized on polymer matrices or solvent impregnated resin.

  14. Sandy Hook Traveler Information System

    DOT National Transportation Integrated Search

    2010-09-01

    This report focuses on equipment and procedural solutions for gathering and disseminating a wide range of visitor information, including real-time traveler information data relating to traffic and parking at the Sandy Hook Unit of the Gateway Recreat...

  15. NASA Tech Briefs, November 2002. Volume 26, No. 11

    NASA Technical Reports Server (NTRS)

    2002-01-01

    Topics include: a technology focus on engineering materials, electronic components and systems, software, mechanics, machinery/automation, manufacturing, bio-medical, physical sciences, information sciences book and reports, and a special section of Photonics Tech Briefs.

  16. NASA Tech Briefs, October 2002. Volume 26, No. 10

    NASA Technical Reports Server (NTRS)

    2002-01-01

    Topics include: a technology focus on sensors, electronic components and systems, software, materials, materials, mechanics, manufacturing, physical sciences, information sciences, book and reports, motion control and a special section of Photonics Tech Briefs.

  17. NASA Tech Briefs, July 2002. Volume 26, No. 7

    NASA Technical Reports Server (NTRS)

    2002-01-01

    Topics include: a technology focus sensors, software, electronic components and systems, materials, mechanics, machinery/automation, manufacturing, bio-medical, physical sciences, information sciences, book and reports, and a special section of Photonics Tech Briefs.

  18. NASA Tech Briefs, January 1996. Volume 20, No. 1

    NASA Technical Reports Server (NTRS)

    1996-01-01

    This issue has a special focus on sensors, and include articles on Electronic Components and Circuits, Electronic Systems, Physical Sciences, Materials, Computer Programs, Mechanics, Machinery/Automation, Manufacturing/Fabrication, and Mathematics and Information Sciences

  19. Transforming User Needs into Functional Requirements for an Antibiotic Clinical Decision Support System

    PubMed Central

    Bright, T.J.

    2013-01-01

    Summary Background Many informatics studies use content analysis to generate functional requirements for system development. Explication of this translational process from qualitative data to functional requirements can strengthen the understanding and scientific rigor when applying content analysis in informatics studies. Objective To describe a user-centered approach transforming emergent themes derived from focus group data into functional requirements for informatics solutions and to illustrate these methods to the development of an antibiotic clinical decision support system (CDS). Methods The approach consisted of five steps: 1) identify unmet therapeutic planning information needs via Focus Group Study-I, 2) develop a coding framework of therapeutic planning themes to refine the domain scope to antibiotic therapeutic planning, 3) identify functional requirements of an antibiotic CDS system via Focus Group Study-II, 4) discover informatics solutions and functional requirements from coded data, and 5) determine the types of information needed to support the antibiotic CDS system and link with the identified informatics solutions and functional requirements. Results The coding framework for Focus Group Study-I revealed unmet therapeutic planning needs. Twelve subthemes emerged and were clustered into four themes; analysis indicated a need for an antibiotic CDS intervention. Focus Group Study-II included five types of information needs. Comments from the Barrier/Challenge to information access and Function/Feature themes produced three informatics solutions and 13 functional requirements of an antibiotic CDS system. Comments from the Patient, Institution, and Domain themes generated required data elements for each informatics solution. Conclusion This study presents one example explicating content analysis of focus group data and the analysis process to functional requirements from narrative data. Illustration of this 5-step method was used to develop an antibiotic CDS system, resolving unmet antibiotic prescribing needs. As a reusable approach, these techniques can be refined and applied to resolve unmet information needs with informatics interventions in additional domains. PMID:24454586

  20. Columbia River System Operation Review : Final Environmental Impact Statement, Appendix N: Wildlife.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Columbia River System Operation Review

    1995-11-01

    The Columbia River System is a vast and complex combination of Federal and non-Federal facilities used for many purposes including power production, irrigation, navigation, flood control, recreation, fish and wildlife habitat and municipal and industrial water supply. Each river use competes for the limited water resources in the Columbia River Basin. This technical appendix addresses only the effects of alternative system operating strategies for managing the Columbia River system. The environmental impact statement (EIS) itself and some of the other appendices present analyses of the alternative approaches to the other three decisions considered as part of the SOR. This documentmore » is the product of the Wildlife Work Group, focusing on wildlife impacts but not including fishes. Topics covered include the following: scope and process; existing and affected environment, including specific discussion of 18 projects in the Columbia river basin. Analysis, evaluation, and alternatives are presented for all projects. System wide impacts to wildlife are also included.« less

  1. Description and verification of a U.S. Naval Research Lab's loosely coupled data assimilation system for the Navy's Earth System Model

    NASA Astrophysics Data System (ADS)

    Barton, N. P.; Metzger, E. J.; Smedstad, O. M.; Ruston, B. C.; Wallcraft, A. J.; Whitcomb, T.; Ridout, J. A.; Zamudio, L.; Posey, P.; Reynolds, C. A.; Richman, J. G.; Phelps, M.

    2017-12-01

    The Naval Research Laboratory is developing an Earth System Model (NESM) to provide global environmental information to meet Navy and Department of Defense (DoD) operations and planning needs from the upper atmosphere to under the sea. This system consists of a global atmosphere, ocean, ice, wave, and land prediction models and the individual models include: atmosphere - NAVy Global Environmental Model (NAVGEM); ocean - HYbrid Coordinate Ocean Model (HYCOM); sea ice - Community Ice CodE (CICE); WAVEWATCH III™; and land - NAVGEM Land Surface Model (LSM). Data assimilation is currently loosely coupled between the atmosphere component using a 6-hour update cycle in the Naval Research Laboratory (NRL) Atmospheric Variational Data Assimilation System - Accelerated Representer (NAVDAS-AR) and the ocean/ice components using a 24-hour update cycle in the Navy Coupled Ocean Data Assimilation (NCODA) with 3 hours of incremental updating. This presentation will describe the US Navy's coupled forecast model, the loosely coupled data assimilation, and compare results against stand-alone atmosphere and ocean/ice models. In particular, we will focus on the unique aspects of this modeling system, which includes an eddy resolving ocean model and challenges associated with different update-windows and solvers for the data assimilation in the atmosphere and ocean. Results will focus on typical operational diagnostics for atmosphere, ocean, and ice analyses including 500 hPa atmospheric height anomalies, low-level winds, temperature/salinity ocean depth profiles, ocean acoustical proxies, sea ice edge, and sea ice drift. Overall, the global coupled system is performing with comparable skill to the stand-alone systems.

  2. Focusing X-ray free-electron laser pulses using Kirkpatrick-Baez mirrors at the NCI hutch of the PAL-XFEL.

    PubMed

    Kim, Jangwoo; Kim, Hyo Yun; Park, Jaehyun; Kim, Sangsoo; Kim, Sunam; Rah, Seungyu; Lim, Jun; Nam, Ki Hyun

    2018-01-01

    The Pohang Accelerator Laboratory X-ray Free-Electron Laser (PAL-XFEL) is a recently commissioned X-ray free-electron laser (XFEL) facility that provides intense ultrashort X-ray pulses based on the self-amplified spontaneous emission process. The nano-crystallography and coherent imaging (NCI) hutch with forward-scattering geometry is located at the hard X-ray beamline of the PAL-XFEL and provides opportunities to perform serial femtosecond crystallography and coherent X-ray diffraction imaging. To produce intense high-density XFEL pulses at the interaction positions between the X-rays and various samples, a microfocusing Kirkpatrick-Baez (KB) mirror system that includes an ultra-precision manipulator has been developed. In this paper, the design of a KB mirror system that focuses the hard XFEL beam onto a fixed sample point of the NCI hutch, which is positioned along the hard XFEL beamline, is described. The focusing system produces a two-dimensional focusing beam at approximately 2 µm scale across the 2-11 keV photon energy range. XFEL pulses of 9.7 keV energy were successfully focused onto an area of size 1.94 µm × 2.08 µm FWHM.

  3. New Directions for NASA's Advanced Life Support Program

    NASA Technical Reports Server (NTRS)

    Barta, Daniel J.

    2006-01-01

    Advanced Life Support (ALS), an element of Human Systems Research and Technology s (HSRT) Life Support and Habitation Program (LSH), has been NASA s primary sponsor of life support research and technology development for the agency. Over its history, ALS sponsored tasks across a diverse set of institutions, including field centers, colleges and universities, industry, and governmental laboratories, resulting in numerous publications and scientific articles, patents and new technologies, as well as education and training for primary, secondary and graduate students, including minority serving institutions. Prior to the Vision for Space Exploration (VSE) announced on January 14th, 2004 by the President, ALS had been focused on research and technology development for long duration exploration missions, emphasizing closed-loop regenerative systems, including both biological and physicochemical. Taking a robust and flexible approach, ALS focused on capabilities to enable visits to multiple potential destinations beyond low Earth orbit. ALS developed requirements, reference missions, and assumptions upon which to structure and focus its development program. The VSE gave NASA a plan for steady human and robotic space exploration based on specific, achievable goals. Recently, the Exploration Systems Architecture Study (ESAS) was chartered by NASA s Administrator to determine the best exploration architecture and strategy to implement the Vision. The study identified key technologies required to enable and significantly enhance the reference exploration missions and to prioritize near-term and far-term technology investments. This technology assessment resulted in a revised Exploration Systems Mission Directorate (ESMD) technology investment plan. A set of new technology development projects were initiated as part of the plan s implementation, replacing tasks previously initiated under HSRT and its sister program, Exploration Systems Research and Technology (ESRT). The Exploration Life Support (ELS) Project, under the Exploration Technology Development Program, has recently been initiated to perform directed life support technology development in support of Constellation and the Crew Exploration Vehicle (CEV). ELS) has replaced ALS, with several major differences. Thermal Control Systems have been separated into a new stand alone project (Thermal Systems for Exploration Missions). Tasks in Advanced Food Technology have been relocated to the Human Research Program. Tasks in a new discipline area, Habitation Engineering, have been added. Research and technology development for capabilities required for longer duration stays on the Moon and Mars, including bioregenerative system, have been deferred.

  4. Advanced-technology space station study: Summary of systems and pacing technologies

    NASA Technical Reports Server (NTRS)

    Butterfield, A. J.; Garn, P. A.; King, C. B.; Queijo, M. J.

    1990-01-01

    The principal system features defined for the Advanced Technology Space Station are summarized and the 21 pacing technologies identified during the course of the study are described. The descriptions of system configurations were extracted from four previous study reports. The technological areas focus on those systems particular to all large spacecraft which generate artificial gravity by rotation. The summary includes a listing of the functions, crew requirements and electrical power demand that led to the studied configuration. The pacing technologies include the benefits of advanced materials, in-orbit assembly requirements, stationkeeping, evaluations of electrical power generation alternates, and life support systems. The descriptions of systems show the potential for synergies and identifies the beneficial interactions that can result from technological advances.

  5. FOXSI-2: Upgrades of the Focusing Optics X-ray Solar Imager for its Second Flight

    NASA Astrophysics Data System (ADS)

    Christe, Steven; Glesener, Lindsay; Buitrago-Casas, Camilo; Ishikawa, Shin-Nosuke; Ramsey, Brian; Gubarev, Mikhail; Kilaru, Kiranmayee; Kolodziejczak, Jeffery J.; Watanabe, Shin; Takahashi, Tadayuki; Tajima, Hiroyasu; Turin, Paul; Shourt, Van; Foster, Natalie; Krucker, Sam

    2016-03-01

    The Focusing Optics X-ray Solar Imager (FOXSI) sounding rocket payload flew for the second time on 2014 December 11. To enable direct Hard X-Ray (HXR) imaging spectroscopy, FOXSI makes use of grazing-incidence replicated focusing optics combined with fine-pitch solid-state detectors. FOXSI’s first flight provided the first HXR focused images of the Sun. For FOXSI’s second flight several updates were made to the instrument including updating the optics and detectors as well as adding a new Solar Aspect and Alignment System (SAAS). This paper provides an overview of these updates as well as a discussion of their measured performance.

  6. Focused Wind Mass Accretion in Mira AB

    NASA Astrophysics Data System (ADS)

    Karovska, Margarita; de Val-Borro, M.; Hack, W.; Raymond, J.; Sasselov, D.; Lee, N. P.

    2011-05-01

    At a distance of about only 100pc, Mira AB is the nearest symbiotic system containing an Asymptotic Giant Branch (AGB) star (Mira A), and a compact accreting companion (Mira B) at about 0.5" from Mira A. Symbiotic systems are interacting binaries with a key evolutionary importance as potential progenitors of a fraction of asymmetric Planetary Nebulae, and SN type Ia, cosmological distance indicators. The region of interaction has been studied using high-angular resolution, multiwavelength observations ranging from radio to X-ray wavelengths. Our results, including high-angular resolution Chandra imaging, show a "bridge" between Mira A and Mira B, indicating gravitational focusing of the Mira A wind, whereby components exchange matter directly in addition to the wind accretion. We carried out a study using 2-D hydrodynamical models of focused wind mass accretion to determine the region of wind acceleration and the characteristics of the accretion in Mira AB. We highlight some of our results and discuss the impact on our understanding of accretion processes in symbiotic systems and other detached and semidetached interacting systems.

  7. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kim, Young Jin

    The PowerPoint presentation focused on research goals, specific information about the atomic magnetometer, response and resolution factors of the SERF magnetometer, FC+AM systems, tests of field transfer and resolution on FC, gradient cancellation, testing of AM performance, ideas for a multi-channel AM, including preliminary sensitivity testing, and a description of a 6 channel DAQ system. A few ideas for future work ended the presentation.

  8. [The Andrew Heiskell Library for the Blind and Physically Handicapped.] A Library with a Difference. Projects and Experiments.

    ERIC Educational Resources Information Center

    Jarkon, Joe; Fitzpatrick, Vicki, Ed.

    This publication describes the Andrew Heiskell Library for the Blind and Physically Handicapped, a regional library for the National Library Service (NLS) example of the creative use of physical space and innovative technology. The publication focuses on the materials-handling system designed for the new facility, including system design…

  9. Computer Technologies and Consumer Information. Interactive Videotex Systems. Report by the Committee on Consumer Policy.

    ERIC Educational Resources Information Center

    Organisation for Economic Cooperation and Development, Paris (France).

    This report focuses on the consumer information potential of computerized telecommunication systems, their possible advantages and drawbacks for the consumer, and the new policy issues created by the new medium, i.e., the possible economic, social, and legal implications for consumers. Topics addressed include the main features of the new…

  10. Law Studies: The Criminal Justice System.

    ERIC Educational Resources Information Center

    Experimental Curriculum Bulletin, 1978

    1978-01-01

    This bulletin on criminal justice focuses on selected aspects of the U.S. legal system, including the police, the courts, and the prisons as well as on the protections and guarantees that reinforce the legitimacy of the U.S. legal process. Unit 1, "The Role of Law in a Free Society," is designed to enhance the awareness of students about…

  11. THE NEEDS OF EDUCATION FOR TELEVISION CHANNEL ALLOCATIONS.

    ERIC Educational Resources Information Center

    BRONSON, VERNON; AND OTHERS

    THIS REPORT IS BASED ON A STUDY DESIGNED SPECIFICALLY TO BRING INTO FOCUS THE NATIONAL PICTURE OF TELEVISION FACILITIES FOR EDUCATION THAT WILL BE NEEDED DURING THE NEXT DECADE. THE SURVEY INCLUDED ALL THE LARGE SCHOOL SYSTEMS IN THE COUNTRY WITH ENROLLMENTS OF 12,000 OR MORE, A NUMBER OF THE SMALLER SYSTEMS, AND ALL THE STATE DEPARTMENTS OF…

  12. Biological Systems, Energy Sources, and Biology Teaching. Biology and Human Welfare.

    ERIC Educational Resources Information Center

    Tribe, Michael; Pritchard, Alan J.

    This five-chapter document (part of a series on biology and human welfare) focuses on biological systems as energy sources and on the teaching of this subject area. Chapter 1 discusses various topics related to energy and ecology, including biomass, photosynthesis and world energy balances, energy flow through ecosystems, and others. Chapter 2…

  13. Playing the (Sexual) Field: The Interactional Basis of Systems of Sexual Stratification

    ERIC Educational Resources Information Center

    Green, Adam Isaiah

    2011-01-01

    Recently, scholars have used a Bourdieusian theory of practice to analyze systems of sexual stratification, including an examination of sexual fields and sexual (or erotic) capital. While the broad structural features of the sexual field have been a point of focus in this latter research, a systematic analysis of the interactional processes that…

  14. Technology Use in Rwandan Secondary Schools: An Assessment of Teachers' Attitudes towards Geographic Information Systems (GIS)

    ERIC Educational Resources Information Center

    Akinyemi, Felicia O.

    2016-01-01

    Technology use is evident in all spheres of human endeavour. Focusing on technology use in education, this paper examines teachers' attitudes towards geographic information system (GIS). An assessment was made of GIS teachers in Rwandan secondary schools. Key areas covered include how GIS is implemented in schools, teachers' attitudes and…

  15. America's Youth Are at Risk: Developing Models for Action in the Nation's Public Libraries.

    ERIC Educational Resources Information Center

    Flum, Judith G.; Weisner, Stan

    1993-01-01

    Discussion of public library support systems for at-risk teens focuses on the Bay Area Library and Information System (BALIS) that was developed to improve library services to at-risk teenagers in the San Francisco Bay area. Highlights include needs assessment; staff training; intervention models; and project evaluation. (10 references) (LRW)

  16. Defense Acquisitions: Assessments of Selected Weapon Programs

    DTIC Science & Technology

    2015-03-01

    offices on technology, design , and manufacturing knowledge; the use of knowledge- based acquisition practices; and the implementation of acquisition...and production maturity using two data-collection instruments, including a questionnaire on issues such as systems engineering reviews, design ...Demonstrating technology maturity is a prerequisite for moving forward into system development, during which the focus should be on design and

  17. Now What? Youth at the Crossroads. 2008 Annual Report

    ERIC Educational Resources Information Center

    Children's Aid Society, 2008

    2008-01-01

    This annual report focuses on teens returning from incarceration in the juvenile justice system. With alarmingly high recidivism rates, many of these young people cycle in and out of the justice system for the rest of their lives. The report includes a brief history of the organization and its commitment to the well-being of New York City…

  18. Method and apparatus for dynamic focusing of ultrasound energy

    DOEpatents

    Candy, James V.

    2002-01-01

    Method and system disclosed herein include noninvasively detecting, separating and destroying multiple masses (tumors, cysts, etc.) through a plurality of iterations from tissue (e.g., breast tissue). The method and system may open new frontiers with the implication of noninvasive treatment of masses in the biomedical area along with the expanding technology of acoustic surgery.

  19. Assessing and Managing Quality of Information Assurance

    DTIC Science & Technology

    2010-11-01

    such as firewalls, antivirus scanning tools and mechanisms for user authentication and authorization. Advanced mission-critical systems often...imply increased risk to DoD information systems. The Process and Organizational Maturity (POM) class focuses on the maturity of the software and...include architectural quality. Common Weakness Enumeration (CWE) is a recent example that highlights the connection between software quality and

  20. NASA Tech Briefs, August 1995. Volume 19, No. 8

    NASA Technical Reports Server (NTRS)

    1995-01-01

    There is a special focus on computer graphics and simulation in this issue. Topics covered include : Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer programs, Mechanics; Machinery; Fabrication Technology; and Mathematics and Information Sciences. There is a section on for Laser Technology, which includes a feature on Moving closer to the suns power.

  1. Glioblastoma Multiforme and Lipid Nanocapsules: A Review.

    PubMed

    Aparicio-Blanco, Juan; Torres-Suárez, Ana-Isabel

    2015-08-01

    Epidemiological data on central nervous system disorders call for a focus on the major hindrance to brain drug delivery, blood-central nervous system barriers. Otherwise, there is little chance of improving the short-term survival of patients with diseases such as glioblastoma multiforme, which is one of the brain disorders associated with many years of life lost. Targetable nanocarriers for treating malignant gliomas are a unique way to overcome low chemotherapeutic levels at target sites devoid of systemic toxicity. This review describes the currently available targetable nanocarriers, focusing particularly on one of the newest nanocarriers, lipid nanocapsules. All of the strategies that are likely to be exploited by lipid nanocapsules to bypass blood-central nervous system barriers, including the most recent targeting approaches (mesenchymal cells), and novel administration routes (convection enhanced delivery) are discussed, together with their most remarkable achievements in glioma-implanted animal models. Although these systems are promising, much research remains to be done in this field.

  2. Luminescent characteristics study of Mather-type dense plasma focus and applications to short-wavelength optical pumping. Final technical report, 1 May 1984-30 September 1985

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kim, K.K.

    A Mather-type dense plasma focus (MDPF) system was designed, built, and tested specifically to study its luminescent characteristics and to assess its potential as a new light source of high-energy, short-wavelength lasers. The luminescence study of MDPF showed that the conversion efficiency from the electrical input to the optical output energies is at least 50%, up to the time the plasma compression is complete. Using the system, for the first time as an optical pump, laser activities were successfully obtained from a variety of liquid organic dyes. Diagnostic capabilities included an optical multichannel analyzer system complete with a computer control,more » a nitrogen-pumped tunable dye-laser system, a high-speed streak/framing camera, a digital laser energy meter, voltage and current probes, and a computer-based data-acquisition system.« less

  3. TeleProbe: design and development of an efficient system for telepathology

    NASA Astrophysics Data System (ADS)

    Ahmed, Wamiq M.; Robinson, J. Paul; Ghafoor, Arif

    2005-10-01

    This paper describes an internet-based system for telepathology. This system provides support for multiple users and exploits the opportunities for optimization that arise in multi-user environment. Techniques for increasing system responsiveness by improving resource utilization and lowering network traffic are explored. Some of the proposed optimizations include an auto-focus module, client and server side caching, and request reordering. These systems can be an economic solution not only for remote pathology consultation but also for pathology and biology education.

  4. Estrogen-IGF-1 interactions in neuroprotection: Ischemic Stroke as a case study

    PubMed Central

    Sohrabji, Farida

    2014-01-01

    The steroid hormone 17b-estradiol and the peptide hormone insulin-like growth factor (IGF)-1 independently exert neuroprotective actions in neurologic diseases such as stroke. Only a few studies have directly addressed the interaction between the two hormone systems, however, there is a large literature that indicates potentially greater interactions between the 17b-estradiol and IGF-1 systems. The present review focuses on key issues related to this interaction including IGF-1 and sex differences and common activation of second messenger systems. Using ischemic stroke as a case study, this review also focuses on independent and cooperative actions of estrogen and IGF-1 on neuroprotection, blood brain barrier integrity, angiogenesis, inflammation and post-stroke epilepsy. Finally, the review also focuses on the astrocyte, a key mediator of post stroke repair, as a local source of 17b-estradiol and IGF-1. This review thus highlights areas where significant new research is needed to clarify the interactions between these two neuroprotectants. PMID:24882635

  5. Review of MRI positioning devices for guiding focused ultrasound systems.

    PubMed

    Yiallouras, C; Damianou, C

    2015-06-01

    This article contains a review of positioning devices that are currently used in the area of magnetic resonance imaging (MRI) guided focused ultrasound surgery (MRgFUS). The paper includes an extensive review of literature published since the first prototype system was invented in 1991. The technology has grown into a fast developing area with application to any organ accessible to ultrasound. The initial design operated using hydraulic principles, while the latest technology incorporates piezoelectric motors. Although, in the beginning there were fears regarding MRI safety, during recent years, the deployment of MR-safe positioning devices in FUS has become routine. Many of these positioning devices are now undergoing testing in clinical trials. Existing MRgFUS systems have been utilized mostly in oncology (fibroids, brain, liver, kidney, bone, pancreas, eye, thyroid, and prostate). It is anticipated that, in the near future, there will be a positioning device for every organ that is accessible by focused ultrasound. Copyright © 2014 John Wiley & Sons, Ltd.

  6. 75 FR 28667 - Market Structure Roundtable

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-21

    ... views of investors, issuers, exchanges, alternative trading systems, financial services firms, high... roundtable will focus on market structure performance, including the events of May 6, metrics for evaluating market structure performance, high frequency trading, and undisplayed liquidity. The roundtable...

  7. Update on Supersonic Jet Noise Research at NASA

    NASA Technical Reports Server (NTRS)

    Henderson, Brenda

    2010-01-01

    An update on jet noise research conducted in the Fundamental Aeronautics and Integrated Systems Research Programs was presented. Highlighted research projects included those focused on the development of prediction tools, diagnostic tools, and noise reduction concepts.

  8. NASA Tech Briefs, February 2002. Volume 26, No. 2

    NASA Technical Reports Server (NTRS)

    2002-01-01

    Topics include:a technology focus on computers, electronic components and systems, software, materials, mechanics,physical sciences machinery, manufacturing/fabrication, mathematics, book and reports, motion control tech briefs and a special section on Photonics Tech Briefs.

  9. Transforming cold chain performance and management in lower-income countries.

    PubMed

    Brison, Mike; LeTallec, Yann

    2017-04-19

    In many countries, one of the common factors limiting full and equitable access to effective immunization is the existence of gaps in cold chain and logistics (CCL) systems. This article focuses on the critical contribution that better management of CCL performance can make in addressing these barriers, as well as some essential practices needed to achieve and sustain these gains. These include (i) an emphasis on continuous improvement in CCL performance indicators, (ii) strong coordination and accountability across multiple stakeholders, and (iii) making the most of limited financial resources. This article is informed by the Clinton Health Access Initiative's (CHAI's) experience working with National Immunization Programs (NIPs) and immunization partners to improve the effectiveness and efficiency of CCL systems (including CCE deployment and maintenance, temperature monitoring and control, stock management and distribution) across ten Gavi-supported "focus" countries. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

  10. Zein-based Nanocarriers as Potential Natural Alternatives for Drug and Gene Delivery: Focus on Cancer Therapy.

    PubMed

    Elzoghby, Ahmed; Freag, May; Mamdouh, Hadeer; Elkhodairy, Kadria

    2017-01-01

    Protein nanocarriers possess unique merits including minimal cytotoxicity, numerous renewable sources, and high drug-binding capability. In opposition to delivery carriers utilizing hydrophilic animal proteins, hydrophobic plant proteins (e.g, zein) have great tendency in fabricating controlled-release particulate carriers without additional chemical modification to stiffen them, which in turn evades the use of toxic chemical crosslinkers. Moreover, zein is related to a class of alcohol-soluble prolamins and generally recognized as safe (GRAS) carrier for drug delivery. Various techniques have been adopted to fabricate zein-based nanoparticulate systems including phase separation coacervation, spray-drying, supercritical anti-solvent approach, electrospinning and self-assembly. This manuscript reviews the recent advances in the zein-based colloidal nano-carrier systems such as nanospheres, nanocapsules, micelles and nanofibers with a special focus on their physicochemical characteristics and drug delivery applications. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  11. Investigations into Performance and Lifetime Enhancements of OPV Devices: Cooperative Research and Development Final Report, CRADA Number CRD-08-263

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ginley, D.

    2014-06-01

    To evaluate Plextronics new additives and derivatives in lithium-ion Battery Applications, Plextronics will provide to NREL, a starting point, including materials and initial data for proof of concept. The central focus of this project is to acertain the nature of the efficacy of the Plextronics additives through physical and electrical characterization, including evaluations of new derivatives, system evaluations on batteries made with Plexcore and to study long term cycling performance differences. The initial focus is to establish Plexcore mode of action to support the commercialization of the first commercial evaluations of Plexcore in Sept. 2013.

  12. The Biosphere: A Decadal Vision

    NASA Technical Reports Server (NTRS)

    Peterson, David L.; Curran, Paul J.; Mlynzcak, Marty; Miller, Richard

    2003-01-01

    This paper focuses on biosphere-climate interactions including the influences of human activities. Recognizing this is only one aspect of biospheric processes, this places an emphasis of those biogeochemical processes that have a profound effect on numerous other aspects of the biosphere and the services it provides, services which are critical to sustaining life on Earth. And, the paper will focus on the various scientific aspects of assessing the availability of fresh water, including its sensitivity to climate variance and land use changes. Finally, this paper hopes to emphasize the potential role that greatly expanded space observations and interactive modeling can play in developing our understanding of Earth and its the living systems.

  13. Filter performance parameters for vectorial high-aperture wave fields.

    PubMed

    Sheppard, Colin J R; Martinez-Corral, M

    2008-03-01

    Performance parameters have been presented that can be used to compare the focusing performance of different optical systems, including the effect of pupil filters. These were originally given for the paraxial case and recently extended to the high-aperture scalar regime. We generalize these parameters to the full vectorial case for an aplanatic optical system illuminated by a plane-polarized wave. The behavior of different optical systems is compared.

  14. Evaluating the effect of the new incentive system for high-risk pressure ulcer patients on wound healing and cost-effectiveness: a cohort study.

    PubMed

    Sanada, Hiromi; Nakagami, Gojiro; Mizokami, Yuko; Minami, Yukiko; Yamamoto, Aya; Oe, Makoto; Kaitani, Toshiko; Iizaka, Shinji

    2010-03-01

    To evaluate the effectiveness and cost-effectiveness of new incentive system for pressure ulcer management, which focused on skilled nurse staffing in terms of rate of healing and medical costs. A prospective cohort study included two types of groups: 39 institutions, which introduced the new incentive system, and 20 non-introduced groups (control). Sixty-seven patients suffering from severe pressure ulcers in the introduced group and 38 patients in the non-introduced group were included. Wound healing and medical costs were monitored weekly for three weeks by their skilled nurses in charge. Healing status and related medical costs. The introduced group showed significantly higher rate of healing compared with the control group at each weekly assessment. Multiple regression analysis revealed that the introduction of the new incentive system was independently associated with the faster healing rate (beta=3.44, P<.001). The budget impact analysis demonstrated that introducing this system could reduce cost of treating severe pressure ulcers by 1.776 billion yen per year. The new incentive system for the management of pressure ulcers, which focused on staffing with skilled nurses can improve healing rate with reduced medical cost. Copyright 2009 Elsevier Ltd. All rights reserved.

  15. Surgical guidance system using hand-held probe with accompanying positron coincidence detector

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Majewski, Stanislaw; Weisenberger, Andrew G.

    A surgical guidance system offering different levels of imaging capability while maintaining the same hand-held convenient small size of light-weight intra-operative probes. The surgical guidance system includes a second detector, typically an imager, located behind the area of surgical interest to form a coincidence guidance system with the hand-held probe. This approach is focused on the detection of positron emitting biomarkers with gamma rays accompanying positron emissions from the radiolabeled nuclei.

  16. DOE Office of Scientific and Technical Information (OSTI.GOV)

    MacAllister, D.J.; Day, R.; McCormack, M.D.

    This paper gives an overview of a major integrated oil company`s experience with artificial intelligence (AI) over the last 5 years, with an emphasis on expert systems. The authors chronicle the development of an AI group, including details on development tool selection, project selection strategies, potential pitfalls, and descriptions of several completed expert systems. Small expert systems produced by teams of petroleum technology experts and experienced expert system developers that are focused in well-defined technical areas have produced substantial benefits and accelerated petroleum technology transfer.

  17. NASA System-Level Design, Analysis and Simulation Tools Research on NextGen

    NASA Technical Reports Server (NTRS)

    Bardina, Jorge

    2011-01-01

    A review of the research accomplished in 2009 in the System-Level Design, Analysis and Simulation Tools (SLDAST) of the NASA's Airspace Systems Program is presented. This research thrust focuses on the integrated system-level assessment of component level innovations, concepts and technologies of the Next Generation Air Traffic System (NextGen) under research in the ASP program to enable the development of revolutionary improvements and modernization of the National Airspace System. The review includes the accomplishments on baseline research and the advancements on design studies and system-level assessment, including the cluster analysis as an annualization standard of the air traffic in the U.S. National Airspace, and the ACES-Air MIDAS integration for human-in-the-loop analyzes within the NAS air traffic simulation.

  18. Distributed systems status and control

    NASA Technical Reports Server (NTRS)

    Kreidler, David; Vickers, David

    1990-01-01

    Concepts are investigated for an automated status and control system for a distributed processing environment. System characteristics, data requirements for health assessment, data acquisition methods, system diagnosis methods and control methods were investigated in an attempt to determine the high-level requirements for a system which can be used to assess the health of a distributed processing system and implement control procedures to maintain an accepted level of health for the system. A potential concept for automated status and control includes the use of expert system techniques to assess the health of the system, detect and diagnose faults, and initiate or recommend actions to correct the faults. Therefore, this research included the investigation of methods by which expert systems were developed for real-time environments and distributed systems. The focus is on the features required by real-time expert systems and the tools available to develop real-time expert systems.

  19. Applications of CRISPR/Cas System to Bacterial Metabolic Engineering.

    PubMed

    Cho, Suhyung; Shin, Jongoh; Cho, Byung-Kwan

    2018-04-05

    The clustered regularly interspaced short palindromic repeats/CRISPR-associated (CRISPR/Cas) adaptive immune system has been extensively used for gene editing, including gene deletion, insertion, and replacement in bacterial and eukaryotic cells owing to its simple, rapid, and efficient activities in unprecedented resolution. Furthermore, the CRISPR interference (CRISPRi) system including deactivated Cas9 (dCas9) with inactivated endonuclease activity has been further investigated for regulation of the target gene transiently or constitutively, avoiding cell death by disruption of genome. This review discusses the applications of CRISPR/Cas for genome editing in various bacterial systems and their applications. In particular, CRISPR technology has been used for the production of metabolites of high industrial significance, including biochemical, biofuel, and pharmaceutical products/precursors in bacteria. Here, we focus on methods to increase the productivity and yield/titer scan by controlling metabolic flux through individual or combinatorial use of CRISPR/Cas and CRISPRi systems with introduction of synthetic pathway in industrially common bacteria including Escherichia coli . Further, we discuss additional useful applications of the CRISPR/Cas system, including its use in functional genomics.

  20. A qualitative analysis of interprofessional healthcare team members' perceptions of patient barriers to healthcare engagement.

    PubMed

    Powell, Rhea E; Doty, Amanda; Casten, Robin J; Rovner, Barry W; Rising, Kristin L

    2016-09-20

    Healthcare systems increasingly engage interprofessional healthcare team members such as case managers, social workers, and community health workers to work directly with patients and improve population health. This study elicited perspectives of interprofessional healthcare team members regarding patient barriers to health and suggestions to address these barriers. This is a qualitative study employing focus groups and semi-structured interviews with 39 interprofessional healthcare team members in Philadelphia to elicit perceptions of patients' needs and experiences with the health system, and suggestions for positioning health care systems to better serve patients. Themes were identified using a content analysis approach. Three focus groups and 21 interviews were conducted with 26 hospital-based and 13 ambulatory-based participants. Three domains emerged to characterize barriers to care: social determinants, health system factors, and patient trust in the health system. Social determinants included insurance and financial shortcomings, mental health and substance abuse issues, housing and transportation-related limitations, and unpredictability associated with living in poverty. Suggestions for addressing these barriers included increased financial assistance from the health system, and building a workforce to address these determinants directly. Health care system factors included poor care coordination, inadequate communication of hospital discharge instructions, and difficulty navigating complex systems. Suggestions for addressing these barriers included enhanced communication between care sites, patient-centered scheduling, and improved patient education especially in discharge planning. Finally, factors related to patient trust of the health system emerged. Participants reported that patients are often intimidated by the health system, mistrusting of physicians, and fearful of receiving a serious diagnosis or prognosis. A suggestion for mitigating these issues was increased visibility of the health system within communities to foster trust and help providers gain a better understanding of unique community needs. This work explored interprofessional healthcare team members' perceptions of patient barriers to healthcare engagement. Participants identified barriers related to social determinants of health, complex system organization, and patient mistrust of the health system. Participants offered concrete suggestions to address these barriers, with suggestions supporting current healthcare reform efforts that aim at addressing social determinants and improving health system coordination and adding new insight into how systems might work to improve patient and community trust.

  1. Ultrashort pulse energy distribution for propulsion in space

    NASA Astrophysics Data System (ADS)

    Bergstue, Grant Jared

    This thesis effort focuses on the development of a novel, space-based ultrashort pulse transmission system for spacecraft. The goals of this research include: (1) ultrashort pulse transmission strategies for maximizing safety and efficiency; (2) optical transmission system requirements; (3) general system requirements including control techniques for stabilization; (4) optical system requirements for achieving effective ablative propulsion at the receiving spacecraft; and (5) ultrashort pulse transmission capabilities required for future missions in space. A key element of the research is the multiplexing device required for aligning the ultrashort pulses from multiple laser sources along a common optical axis for transmission. This strategy enables access to the higher average and peak powers required for useful missions in space.

  2. ILLiad: Customer-Focused Interlibrary Loan Automation.

    ERIC Educational Resources Information Center

    Kriz, Harry M.; Glover, M. Jason; Ford, Kevin C.

    1998-01-01

    Describes ILLiad (Interlibrary Loan Internet Accessible Database), software that examines the current state of interlibrary loan borrowing requests at Virginia Polytechnic Institute and State University. Topics include system requirements, user procedures, staff procedures, copyright clearance, OCLC, and future developments. (LRW)

  3. Task-Based Information Searching.

    ERIC Educational Resources Information Center

    Vakkari, Pertti

    2003-01-01

    Reviews studies on the relationship between task performance and information searching by end-users, focusing on information searching in electronic environments and information retrieval systems. Topics include task analysis; task characteristics; search goals; modeling information searching; modeling search goals; information seeking behavior;…

  4. Multi-Agent Information Classification Using Dynamic Acquaintance Lists.

    ERIC Educational Resources Information Center

    Mukhopadhyay, Snehasis; Peng, Shengquan; Raje, Rajeev; Palakal, Mathew; Mostafa, Javed

    2003-01-01

    Discussion of automated information services focuses on information classification and collaborative agents, i.e. intelligent computer programs. Highlights include multi-agent systems; distributed artificial intelligence; thesauri; document representation and classification; agent modeling; acquaintances, or remote agents discovered through…

  5. Implementation of sustainability in bridge design, construction and maintenance.

    DOT National Transportation Integrated Search

    2012-12-01

    The focus of this research is to develop a framework for more sustainable design and construction : processes for new bridges, and sustainable maintenance practices for existing bridges. The framework : includes a green rating system for bridges. The...

  6. Procurement Without Problems: Preparing the RFP.

    ERIC Educational Resources Information Center

    Epstein, Susan Baerg

    1983-01-01

    Discussion of factors contributing to successful procurement of automated library system focuses on preparation of Request for Proposal (RFP) and elements included in the RFP--administrative requirements, functional requirements, performance requirements, reliability requirements, testing procedures, standardized response language, location table,…

  7. Integrating Module - NEMS Documentation

    EIA Publications

    2014-01-01

    Provides an overview of the complete National Energy Modeling System (NEMS) model, and includes brief descriptions of the modules with which the Integrating Module interacts. The emphasis and focus, however, is on the structure and function of the Integrating Module of NEMS.

  8. Dynamic wind-tunnel testing of active controls by the NASA Langley Research Center

    NASA Technical Reports Server (NTRS)

    Abel, I.; Doggett, R. V.; Newsom, J. R.; Sandford, M.

    1984-01-01

    Dynamic wind-tunnel testing of active controls by the NASA Langley Research Center is presented. Seven experimental studies that were accomplished to date are described. Six of the studies focus on active flutter suppression. The other focuses on active load alleviation. In addition to presenting basic results for these experimental studies, topics including model design and construction, control law synthesis, active control system implementation, and wind-tunnel test techniques are discussed.

  9. Towards a Conceptual Design of a Cross-Domain Integrative Information System for the Geosciences

    NASA Astrophysics Data System (ADS)

    Zaslavsky, I.; Richard, S. M.; Valentine, D. W.; Malik, T.; Gupta, A.

    2013-12-01

    As geoscientists increasingly focus on studying processes that span multiple research domains, there is an increased need for cross-domain interoperability solutions that can scale to the entire geosciences, bridging information and knowledge systems, models, software tools, as well as connecting researchers and organization. Creating a community-driven cyberinfrastructure (CI) to address the grand challenges of integrative Earth science research and education is the focus of EarthCube, a new research initiative of the U.S. National Science Foundation. We are approaching EarthCube design as a complex socio-technical system of systems, in which communication between various domain subsystems, people and organizations enables more comprehensive, data-intensive research designs and knowledge sharing. In particular, we focus on integrating 'traditional' layered CI components - including information sources, catalogs, vocabularies, services, analysis and modeling tools - with CI components supporting scholarly communication, self-organization and social networking (e.g. research profiles, Q&A systems, annotations), in a manner that follows and enhances existing patterns of data, information and knowledge exchange within and across geoscience domains. We describe an initial architecture design focused on enabling the CI to (a) provide an environment for scientifically sound information and software discovery and reuse; (b) evolve by factoring in the impact of maturing movements like linked data, 'big data', and social collaborations, as well as experience from work on large information systems in other domains; (c) handle the ever increasing volume, complexity and diversity of geoscience information; (d) incorporate new information and analytical requirements, tools, and techniques, and emerging types of earth observations and models; (e) accommodate different ideas and approaches to research and data stewardship; (f) be responsive to the existing and anticipated needs of researchers and organizations representing both established and emerging CI users; and (g) make best use of NSF's current investment in the geoscience CI. The presentation will focus on the challenges and methodology of EarthCube CI design, in particular on supporting social engagement and interaction between geoscientists and computer scientists as a core function of EarthCube architecture. This capability must include mechanisms to not only locate and integrate available geoscience resources, but also engage individuals and projects, research products and publications, and enable efficient communication across many EarthCube stakeholders leading to long-term institutional alignment and trusted collaborations.

  10. An Automated Approach to Reasoning Under Multiple Perspectives

    NASA Technical Reports Server (NTRS)

    deBessonet, Cary

    2004-01-01

    This is the final report with emphasis on research during the last term. The context for the research has been the development of an automated reasoning technology for use in SMS (symbolic Manipulation System), a system used to build and query knowledge bases (KBs) using a special knowledge representation language SL (Symbolic Language). SMS interpreters assertive SL input and enters the results as components of its universe. The system operates in two basic models: 1) constructive mode (for building KBs); and 2) query/search mode (for querying KBs). Query satisfaction consists of matching query components with KB components. The system allows "penumbral matches," that is, matches that do not exactly meet the specifications of the query, but which are deemed relevant for the conversational context. If the user wants to know whether SMS has information that holds, say, for "any chow," the scope of relevancy might be set so that the system would respond based on a finding that it has information that holds for "most dogs," although this is not exactly what was called for by the query. The response would be qualified accordingly, as would normally be the case in ordinary human conversation. The general goal of the research was to develop an approach by which assertive content could be interpreted from multiple perspectives so that reasoning operations could be successfully conducted over the results. The interpretation of an SL statement such as, "{person believes [captain (asserted (perhaps)) (astronaut saw (comet (bright)))]}," which in English would amount to asserting something to the effect that, "Some person believes that a captain perhaps asserted that an astronaut saw a bright comet," would require the recognition of multiple perspectives, including some that are: a) epistemically-based (focusing on "believes"); b) assertion-based (focusing on "asserted"); c) perception-based (focusing on "saw"); d) adjectivally-based (focusing on "bight"); and e) modally-based (focusing on "perhaps"). Any conclusion reached under a line of reasoning that employs such an assertion or its associated implications should somehow reflect the employed perspectives. The investigators made significant progress in developing an approach that would enable a system to conduct reasoning operations over assertions of this kind while maintaining consistency in its knowledge bases. Significant accomplishments were made in the areas of: 1) integration and inferencing; 2) generation of perspectives, including wholistic ad composite views; and 3) consistency maintenance.

  11. Veterans’ Preferences for Exchanging Information Using Veterans Affairs Health Information Technologies: Focus Group Results and Modeling Simulations

    PubMed Central

    Chavez, Margeaux; Nazi, Kim; Antinori, Nicole; Melillo, Christine; Cotner, Bridget A; Hathaway, Wendy; Cook, Ashley; Wilck, Nancy; Noonan, Abigail

    2017-01-01

    Background The Department of Veterans Affairs (VA) has multiple health information technology (HIT) resources for veterans to support their health care management. These include a patient portal, VetLink Kiosks, mobile apps, and telehealth services. The veteran patient population has a variety of needs and preferences that can inform current VA HIT redesign efforts to meet consumer needs. Objective This study aimed to describe veterans’ experiences using the current VA HIT and identify their vision for the future of an integrated VA HIT system. Methods Two rounds of focus group interviews were conducted with a single cohort of 47 veterans and one female caregiver recruited from Bedford, Massachusetts, and Tampa, Florida. Focus group interviews included simulation modeling activities and a self-administered survey. This study also used an expert panel group to provide data and input throughout the study process. High-fidelity, interactive simulations were created and used to facilitate collection of qualitative data. The simulations were developed based on system requirements, data collected through operational efforts, and participants' reported preferences for using VA HIT. Pairwise comparison activities of HIT resources were conducted with both focus groups and the expert panel. Rapid iterative content analysis was used to analyze qualitative data. Descriptive statistics summarized quantitative data. Results Data themes included (1) current use of VA HIT, (2) non-VA HIT use, and (3) preferences for future use of VA HIT. Data indicated that, although the Secure Messaging feature was often preferred, a full range of HIT options are needed. These data were then used to develop veteran-driven simulations that illustrate user needs and expectations when using a HIT system and services to access VA health care services. Conclusions Patient participant redesign processes present critical opportunities for creating a human-centered design. Veterans value virtual health care options and prefer standardized, integrated, and synchronized user-friendly interface designs. PMID:29061553

  12. Determination of rate of customer focus in educational programs at Isfahan University of Medical Sciences(1) based on students' viewpoints.

    PubMed

    Shams, Assadollah; Yarmohammadian, Mohammad Hosein; Abbarik, Hadi Hayati

    2012-01-01

    Today, the challenges of quality improvement and customer focus as well as systems development are important and inevitable matters in higher education institutes. There are some highly competitive challenges among educational institutes, including accountability to social needs, increasing costs of education, diversity in educational methods and centers and their consequent increasing competition, and the need for adaptation of new information and knowledge to focus on students as the main customers. Hence, the purpose of this study was to determine the rate of costumer focus based on Isfahan University of Medical Sciences students' viewpoints and to suggest solutions to improve this rate. This was a cross-sectional study carried out in 2011. The statistical population included all the students of seven faculties of Isfahan University of Medical Sciences. According to statistical formulae, the sample size consisted of 384 subjects. Data collection tools included researcher-made questionnaire whose reliability was found to be 87% by Cronbach's alpha coefficient. Finally, using the SPSS statistical software and statistical methods of independent t-test and one-way analysis of variance (ANOVA), Likert scale based data were analyzed. The mean of overall score for customer focus (student-centered) of Isfahan University of Medical Sciences was 46.54. Finally, there was a relation between the mean of overall score for customer focus and gender, educational levels, and students' faculties. Researcher suggest more investigation between Medical University and others. It is a difference between medical sciences universities and others regarding the customer focus area, since students' gender must be considered as an effective factor in giving healthcare services quality. In order to improve the customer focus, it is essential to take facilities, field of study, faculties, and syllabus into consideration.

  13. Determination of rate of customer focus in educational programs at Isfahan University of Medical Sciences1 based on students’ viewpoints

    PubMed Central

    Shams, Assadollah; Yarmohammadian, Mohammad Hosein; Abbarik, Hadi Hayati

    2012-01-01

    Background: Today, the challenges of quality improvement and customer focus as well as systems development are important and inevitable matters in higher education institutes. There are some highly competitive challenges among educational institutes, including accountability to social needs, increasing costs of education, diversity in educational methods and centers and their consequent increasing competition, and the need for adaptation of new information and knowledge to focus on students as the main customers. Hence, the purpose of this study was to determine the rate of costumer focus based on Isfahan University of Medical Sciences students’ viewpoints and to suggest solutions to improve this rate. Materials and Methods: This was a cross-sectional study carried out in 2011. The statistical population included all the students of seven faculties of Isfahan University of Medical Sciences. According to statistical formulae, the sample size consisted of 384 subjects. Data collection tools included researcher-made questionnaire whose reliability was found to be 87% by Cronbach's alpha coefficient. Finally, using the SPSS statistical software and statistical methods of independent t-test and one-way analysis of variance (ANOVA), Likert scale based data were analyzed. Results: The mean of overall score for customer focus (student-centered) of Isfahan University of Medical Sciences was 46.54. Finally, there was a relation between the mean of overall score for customer focus and gender, educational levels, and students’ faculties. Researcher suggest more investigation between Medical University and others. Conclusion: It is a difference between medical sciences universities and others regarding the customer focus area, since students’ gender must be considered as an effective factor in giving healthcare services quality. In order to improve the customer focus, it is essential to take facilities, field of study, faculties, and syllabus into consideration. PMID:23555127

  14. Rapid flood loss estimation for large scale floods in Germany

    NASA Astrophysics Data System (ADS)

    Schröter, Kai; Kreibich, Heidi; Merz, Bruno

    2013-04-01

    Rapid evaluations of flood events are needed for efficient responses both in emergency management and financial appraisal. Beyond that, closely monitoring and documenting the formation and development of flood events and their impacts allows for an improved understanding and in depth analyses of the interplay between meteorological, hydrological, hydraulic and societal causes leading to flood damage. This contribution focuses on the development of a methodology for the rapid assessment of flood events. In the first place, the focus is on the prediction of damage to residential buildings caused by large scale floods in Germany. For this purpose an operational flood event analysis system is developed. This system has basic spatial thematic data available and supports data capturing about the current flood situation. This includes the retrieval of online gauge data and the integration of remote sensing data. Further, it provides functionalities to evaluate the current flood situation, to assess the hazard extent and intensity and to estimate the current flood impact using the flood loss estimation model FLEMOps+r. The operation of the flood event analysis system will be demonstrated for the past flood event from January 2011 with a focus on the Elbe/Saale region. On this grounds, further requirements and potential for improving the information basis as for instance by including hydrological and /or hydraulic model results as well as information from social sensors will be discussed.

  15. NASA's Next Generation Launch Technology Program - Strategy and Plans

    NASA Technical Reports Server (NTRS)

    Hueter, Uwe

    2003-01-01

    The National Aeronautics and Space Administration established a new program office, Next Generation Launch Technology (NGLT) Program Office, last year to pursue technologies for future space launch systems. NGLT will fund research in key technology areas such as propulsion, launch vehicles, operations and system analyses. NGLT is part of NASA s Integrated Space Technology Plan. The NGLT Program is sponsored by NASA s Office of Aerospace Technology and is part of the Space Launch Initiative theme that includes both NGLT and Orbital Space Plane. NGLT will focus on technology development to increase safety and reliability and reduce overall costs associated with building, flying and maintaining the nation s next-generations of space launch vehicles. These investments will be guided by systems engineering and analysis with a focus on the needs of National customers.

  16. Scanning systems for particle cancer therapy

    DOEpatents

    Trbojevic, Dejan

    2015-08-04

    A particle beam to treat malignant tissue is delivered to a patient by a gantry. The gantry includes a plurality of small magnets sequentially arranged along a beam tube to transfer the particle beam with strong focusing and a small dispersion function, whereby a beam size is very small, allowing for the small magnet size. Magnets arranged along the beam tube uses combined function magnets where the magnetic field is a combination of a bending dipole field with a focusing or defocusing quadrupole field. A triplet set of combined function magnets defines the beam size at the patient. A scanning system of magnets arranged along the beam tube after the bending system delivers the particle beam in a direction normal to the patient, to minimize healthy skin and tissue exposure to the particle beam.

  17. Health financing options for Fiji's health system.

    PubMed

    Pande, Madhukar

    2003-09-01

    Fiji is currently implementing health care reforms with the first phase of reforms focusing on decentralization of the health system. Part of this effort focuses on looking at financing options. Some options for financing health care include private health insurance, social insurance, community financing, user-pays system (out-of-pocket), health savings accounts, government taxation and subsidies, and overseas loans and aid funding. This paper addresses all these options in detail and provides an analysis into each of these options relevance to Fiji and in some instances to other nations in the South Pacific region. Given the relative small populations of Fiji and its neighbouring nations, a regional approach to financing could prove more viable in the longer-term, however political, social, economic, legal and cultural issues will need to seriously explored.

  18. Forensic, Cultural, and Systems Issues in Child Sexual Abuse Cases--Part 2: Research and Practitioner Issues

    ERIC Educational Resources Information Center

    Tishelman, Amy C.; Geffner, Robert

    2010-01-01

    This article introduces the second issue of the special double issue focusing on forensic, cultural, and systems issues in child sexual abuse cases. We briefly review the articles, which include a discussion of child sexual abuse myths, an empirical analysis of extended child sexual abuse evaluations, an article on the role of the medical provider…

  19. Access to Vocational Education. A Planning System for Local Secondary and Post-Secondary Program and Facility Accessibility. Step 1: Identifying Barriers.

    ERIC Educational Resources Information Center

    Rice, Eric; And Others

    This guidebook focuses on the first of five steps included in a planning system for improving local secondary and postsecondary program and facilities accessibility: identifying barriers. The first five sections of the booklet are comprised of self-instructional descriptions of five needs-assessment procedures that can be used to identify…

  20. Data Stewardship: Managing Personally Identifiable Information in Electronic Student Education Records. SLDS Technical Brief 2. NCES 2011-602

    ERIC Educational Resources Information Center

    National Center for Education Statistics, 2010

    2010-01-01

    The growth of electronic student data in America's education system has focused attention on the ways these data are collected, processed, stored, and used. The use of records in Statewide Longitudinal Data Systems to follow the progress of individual students over time requires maintaining student education records that include information that…

  1. A Statistically Based Training Diagnostic Tool for Marine Aviation

    DTIC Science & Technology

    2014-06-01

    mission essential task list MDG maneuver description guide MOS military occupational specialty MSHARP Marine Sierra Hotel Aviation Reporting Program...include the Defense Readiness Reporting System (DRRS) Marine Corps, the Current Readiness Program (CRP), and the Marine Sierra Hotel Aviation...Beuschel, 2008). Many of these systems focus on business decisions regarding how companies can increase their bottom line, by appealing to customers more

  2. Access to Vocational Education. A Planning System for Local Secondary and Post-Secondary Program and Facility Accessibility. Step 3: Generating Strategies.

    ERIC Educational Resources Information Center

    Rice, Eric; And Others

    This guidebook focuses on the third of five steps included in a planning system for improving local secondary and postsecondary program and facilities accessibility: generating strategies. The guidebook is comprised of four sections, each describing a specific technique for generating strategies. Techniques presented are (1) nominal group…

  3. The Family Support System: Comparative Analysis of Research Projects Funded by the Administration on Aging.

    ERIC Educational Resources Information Center

    Hofer, Andrew

    This paper presents a comparative analysis of eight research projects funded by the Administration on Aging during the 1970s which focused on the family as caregivers and support systems for elderly relatives. A brief description is provided for each project analyzed in this report as well as highlights of major findings, including that the family…

  4. An Evaluation of Independent Learning of the Japanese Hiragana System Using an Interactive CD

    ERIC Educational Resources Information Center

    Geraghty, Barbara; Quinn, Ann Marcus

    2009-01-01

    As Japanese uses three writing systems (hiragana, katakana, and the ideograms known as kanji), and as materials in the target language include all three, it is a major challenge to learn to read and write quickly. This paper focuses on interactive multi-media methods of teaching Japanese reading which foster learner autonomy. As little has been…

  5. Item Banks for Measuring Emotional Distress from the Patient-Reported Outcomes Measurement Information System (PROMIS[R]): Depression, Anxiety, and Anger

    ERIC Educational Resources Information Center

    Pilkonis, Paul A.; Choi, Seung W.; Reise, Steven P.; Stover, Angela M.; Riley, William T.; Cella, David

    2011-01-01

    The authors report on the development and calibration of item banks for depression, anxiety, and anger as part of the Patient-Reported Outcomes Measurement Information System (PROMIS[R]). Comprehensive literature searches yielded an initial bank of 1,404 items from 305 instruments. After qualitative item analysis (including focus groups and…

  6. Weather Observers: A Manipulative Augmented Reality System for Weather Simulations at Home, in the Classroom, and at a Museum

    ERIC Educational Resources Information Center

    Hsiao, Hsien-Sheng; Chang, Cheng-Sian; Lin, Chien-Yu; Wang, Yau-Zng

    2016-01-01

    This study focused on how to enhance the interactivity and usefulness of augmented reality (AR) by integrating manipulative interactive tools with a real-world environment. A manipulative AR (MAR) system, which included 3D interactive models and manipulative aids, was designed and developed to teach the unit "Understanding Weather" in a…

  7. Achieving strategic cost advantages by focusing on back-office efficiency.

    PubMed

    McDowell, Jim

    2010-06-01

    A study of more than 270 hospitals over a four-year period highlighted a number of investments that can reduce hospitals' costs and improve efficiency, including the following: E-procurement systems. Electronic exchange of invoices and payments (and electronic receipt of payments). Human resources IT systems that reduce the need for manual entry of data. Shared services deployment.

  8. The National Manpower Survey of the Criminal Justice System. Volume Two: Law Enforcement.

    ERIC Educational Resources Information Center

    National Planning Association, Washington, DC.

    Focusing on law enforcement personnel at the city, county, and state levels (including police, sheriffs, and highway patrol agencies), this document is one in a series of six volumes reporting the results of the National Manpower Survey (NMS) of the Criminal Justice System. Chapter 1 of six chapters summarizes the major results of a national…

  9. Focusing on the Future: Understanding Faculty Intent to Lead the Land Grant System

    ERIC Educational Resources Information Center

    Lamm, Alexa J.; Lamm, Kevan W.; Strickland, L. Rochelle

    2013-01-01

    Many outside influences are altering higher education including a decline in resources, changes in student demographics, the impacts of technology, and the shift to an information age. The need for faculty members to become leaders that can handle swift changes to the culture of Colleges of Agriculture within the land-grant system are needed now…

  10. Connections. NECC '89: Proceedings of the National Educational Computing Conference (10th, Boston, Massachusetts, June 20-22, 1989).

    ERIC Educational Resources Information Center

    Ryan, William C., Ed.

    The papers presented at the 1989 National Educational Computing Conference focused on ways of using technology to improve educational quality. Topics of the 50 papers and more than 120 abstracts provided in these proceedings include applications of artificial intelligence and the development of expert systems; authoring systems; using the computer…

  11. Indicators of climate impacts for forests: recommendations for the US National Climate Assessment indicators system

    Treesearch

    Linda S. Heath; Sarah M. Anderson; Marla R. Emery; Jeffrey A. Hicke; Jeremy Littell; Alan Lucier; Jeffrey G. Masek; David L. Peterson; Richard Pouyat; Kevin M. Potter; Guy Robertson; Jinelle Sperry; Andrzej Bytnerowicz; Sarah Jovan; Miranda H. Mockrin; Robert Musselman; Bethany K. Schulz; Robert J. Smith; Susan I. Stewart

    2015-01-01

    The Third National Climate Assessment (NCA) process for the United States focused in part on developing a system of indicators to communicate key aspects of the physical climate, climate impacts, vulnerabilities, and preparedness to inform decisionmakers and the public. Initially, 13 active teams were formed to recommend indicators in a range of categories, including...

  12. Quality Assurance Framework Implementation Guide for Isolated Community Power Systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Esterly, Sean R.; Baring-Gould, Edward I.; Burman, Kari A.

    This implementation guide is a companion document to the 'Quality Assurance Framework for Mini-Grids' technical report. This document is intended to be used by one of the many stakeholder groups that take part in the implementation of isolated power systems. Although the QAF could be applied to a single system, it was designed primarily to be used within the context of a larger national or regional rural electrification program in which many individual systems are being installed. This guide includes a detailed overview of the Quality Assurance Framework and provides guidance focused on the implementation of the Framework from themore » perspective of the different stakeholders that are commonly involved in expanding energy development within specific communities or regions. For the successful long-term implementation of a specific rural electrification program using mini-grid systems, six key stakeholders have been identified that are typically engaged, each with a different set of priorities 1. Regulatory agency 2. Governmental ministry 3. System developers 4. Mini-utility 5. Investors 6. Customers/consumers. This document is broken into two distinct sections. The first focuses on the administrative processes in the development and operation of community-based mini-grid programs, while the second focuses on the process around the installation of the mini-grid project itself.« less

  13. Towards public health decision support: a systematic review of bidirectional communication approaches

    PubMed Central

    Dixon, Brian E; Gamache, Roland E; Grannis, Shaun J

    2013-01-01

    Objective To summarize the literature describing computer-based interventions aimed at improving bidirectional communication between clinical and public health. Materials and Methods A systematic review of English articles using MEDLINE and Google Scholar. Search terms included public health, epidemiology, electronic health records, decision support, expert systems, and decision-making. Only articles that described the communication of information regarding emerging health threats from public health agencies to clinicians or provider organizations were included. Each article was independently reviewed by two authors. Results Ten peer-reviewed articles highlight a nascent but promising area of research and practice related to alerting clinicians about emerging threats. Current literature suggests that additional research and development in bidirectional communication infrastructure should focus on defining a coherent architecture, improving interoperability, establishing clear governance, and creating usable systems that will effectively deliver targeted, specific information to clinicians in support of patient and population decision-making. Conclusions Increasingly available clinical information systems make it possible to deliver timely, relevant knowledge to frontline clinicians in support of population health. Future work should focus on developing a flexible, interoperable infrastructure for bidirectional communications capable of integrating public health knowledge into clinical systems and workflows. PMID:23467470

  14. An Object Oriented Extensible Architecture for Affordable Aerospace Propulsion Systems

    NASA Technical Reports Server (NTRS)

    Follen, Gregory J.; Lytle, John K. (Technical Monitor)

    2002-01-01

    Driven by a need to explore and develop propulsion systems that exceeded current computing capabilities, NASA Glenn embarked on a novel strategy leading to the development of an architecture that enables propulsion simulations never thought possible before. Full engine 3 Dimensional Computational Fluid Dynamic propulsion system simulations were deemed impossible due to the impracticality of the hardware and software computing systems required. However, with a software paradigm shift and an embracing of parallel and distributed processing, an architecture was designed to meet the needs of future propulsion system modeling. The author suggests that the architecture designed at the NASA Glenn Research Center for propulsion system modeling has potential for impacting the direction of development of affordable weapons systems currently under consideration by the Applied Vehicle Technology Panel (AVT). This paper discusses the salient features of the NPSS Architecture including its interface layer, object layer, implementation for accessing legacy codes, numerical zooming infrastructure and its computing layer. The computing layer focuses on the use and deployment of these propulsion simulations on parallel and distributed computing platforms which has been the focus of NASA Ames. Additional features of the object oriented architecture that support MultiDisciplinary (MD) Coupling, computer aided design (CAD) access and MD coupling objects will be discussed. Included will be a discussion of the successes, challenges and benefits of implementing this architecture.

  15. Applying airline safety practices to medication administration.

    PubMed

    Pape, Theresa M

    2003-04-01

    Medication administration errors (MAE) continue as major problems for health care institutions, nurses, and patients. However, MAEs are often the result of system failures leading to patient injury, increased hospital costs, and blaming. Costs include those related to increased hospital length of stay and legal expenses. Contributing factors include distractions, lack of focus, poor communication, and failure to follow standard protocols during medication administration.

  16. Solar Electric Propulsion

    NASA Technical Reports Server (NTRS)

    LaPointe, Michael

    2006-01-01

    The Solar Electric Propulsion (SEP) technology area is tasked to develop near and mid-term SEP technology to improve or enable science mission capture while minimizing risk and cost to the end user. The solar electric propulsion investments are primarily driven by SMD cost-capped mission needs. The technology needs are determined partially through systems analysis tasks including the recent "Re-focus Studies" and "Standard Architecture Study." These systems analysis tasks transitioned the technology development to address the near term propulsion needs suitable for cost-capped open solicited missions such as Discovery and New Frontiers Class missions. Major SEP activities include NASA's Evolutionary Xenon Thruster (NEXT), implementing a Standard Architecture for NSTAR and NEXT EP systems, and developing a long life High Voltage Hall Accelerator (HiVHAC). Lower level investments include advanced feed system development and xenon recovery testing. Future plans include completion of ongoing ISP development activities and evaluating potential use of commercial electric propulsion systems for SMD applications. Examples of enhanced mission capability and technology readiness dates shall be discussed.

  17. An Open Avionics and Software Architecture to Support Future NASA Exploration Missions

    NASA Technical Reports Server (NTRS)

    Schlesinger, Adam

    2017-01-01

    The presentation describes an avionics and software architecture that has been developed through NASAs Advanced Exploration Systems (AES) division. The architecture is open-source, highly reliable with fault tolerance, and utilizes standard capabilities and interfaces, which are scalable and customizable to support future exploration missions. Specific focus areas of discussion will include command and data handling, software, human interfaces, communication and wireless systems, and systems engineering and integration.

  18. ENERGY AND OUR ENVIRONMENT: A SYSTEMS AND LIFE ...

    EPA Pesticide Factsheets

    This is a presentation to the North Carolina BREATE Conference on March 28, 2017. This presentation provides an overview of energy modeling capabilities in ORD, and includes examples related to scenario development, water-energy nexus, bioenergy, etc. The focus is on system approaches as well as life cycle assessment data and tools. Provide an overview of system and life cycle approaches to modeling medium to long-term changes in drivers of changes in emissions sources.

  19. About U.S. Natural Gas Pipelines

    EIA Publications

    2007-01-01

    This information product provides the interested reader with a broad and non-technical overview of how the U.S. natural gas pipeline network operates, along with some insights into the many individual pipeline systems that make up the network. While the focus of the presentation is the transportation of natural gas over the interstate and intrastate pipeline systems, information on subjects related to pipeline development, such as system design and pipeline expansion, are also included.

  20. Sleep, offline processing, and vocal learning

    PubMed Central

    Margoliash, Daniel; Schmidt, Marc F

    2009-01-01

    The study of song learning and the neural song system has provided an important comparative model system for the study of speech and language acquisition. We describe some recent advances in the bird song system, focusing on the role of offline processing including sleep in processing sensory information and in guiding developmental song learning. These observations motivate a new model of the organization and role of the sensory memories in vocal learning. PMID:19906416

  1. Content-based fused off-axis object illumination direct-to-digital holography

    DOEpatents

    Price, Jeffery R.

    2006-05-02

    Systems and methods are described for content-based fused off-axis illumination direct-to-digital holography. A method includes calculating an illumination angle with respect to an optical axis defined by a focusing lens as a function of data representing a Fourier analyzed spatially heterodyne hologram; reflecting a reference beam from a reference mirror at a non-normal angle; reflecting an object beam from an object the object beam incident upon the object at the illumination angle; focusing the reference beam and the object beam at a focal plane of a digital recorder to from the content-based off-axis illuminated spatially heterodyne hologram including spatially heterodyne fringes for Fourier analysis; and digitally recording the content based off-axis illuminated spatially heterodyne hologram including spatially heterodyne fringes for Fourier analysis.

  2. Microscale Enhancement of Heat and Mass Transfer for Hydrogen Energy Storage

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Drost, Kevin; Jovanovic, Goran; Paul, Brian

    2015-09-30

    The document summarized the technical progress associated with OSU’s involvement in the Hydrogen Storage Engineering Center of Excellence. OSU focused on the development of microscale enhancement technologies for improving heat and mass transfer in automotive hydrogen storage systems. OSU’s key contributions included the development of an extremely compact microchannel combustion system for discharging hydrogen storage systems and a thermal management system for adsorption based hydrogen storage using microchannel cooling (the Modular Adsorption Tank Insert or MATI).

  3. Operational alternatives for LANDSAT in California

    NASA Technical Reports Server (NTRS)

    Wilson, P.; Gialdini, M. J.

    1981-01-01

    Data integration is defined and examined as the means of promoting data sharing among the various governmental and private geobased information systems in California. Elements of vertical integration considered included technical factors (such as resolution and classification) and institutional factors (such as organizational control, and legal and political barriers). Attempts are made to fit the theoretical elements of vertical integration into a meaningful structure for looking at the problem from a statewide focus. Both manual (mapped) and machine readable data systems are included. Special attention is given to LANDSAT imagery because of its strong potential for integrated use and its primary in the California Integrated Remote Sensing System program.

  4. Supramolecular chemistry and chemical warfare agents: from fundamentals of recognition to catalysis and sensing.

    PubMed

    Sambrook, M R; Notman, S

    2013-12-21

    Supramolecular chemistry presents many possible avenues for the mitigation of the effects of chemical warfare agents (CWAs), including sensing, catalysis and sequestration. To-date, efforts in this field both to study fundamental interactions between CWAs and to design and exploit host systems remain sporadic. In this tutorial review the non-covalent recognition of CWAs is considered from first principles, including taking inspiration from enzymatic systems, and gaps in fundamental knowledge are indicated. Examples of synthetic systems developed for the recognition of CWAs are discussed with a focus on the supramolecular complexation behaviour and non-covalent approaches rather than on the proposed applications.

  5. Gas-Liquid Flows and Phase Separation

    NASA Technical Reports Server (NTRS)

    McQuillen, John

    2004-01-01

    Common issues for space system designers include:Ability to Verify Performance in Normal Gravity prior to Deployment; System Stability; Phase Accumulation & Shedding; Phase Separation; Flow Distribution through Tees & Manifolds Boiling Crisis; Heat Transfer Coefficient; and Pressure Drop.The report concludes:Guidance similar to "A design that operates in a single phase is less complex than a design that has two-phase flow" is not always true considering the amount of effort spent on pressurizing, subcooling and phase separators to ensure single phase operation. While there is still much to learn about two-phase flow in reduced gravity, we have a good start. Focus now needs to be directed more towards system level problems .

  6. Perspectives on object manipulation and action grammar for percussive actions in primates

    PubMed Central

    Hayashi, Misato

    2015-01-01

    The skill of object manipulation is a common feature of primates including humans, although there are species-typical patterns of manipulation. Object manipulation can be used as a comparative scale of cognitive development, focusing on its complexity. Nut cracking in chimpanzees has the highest hierarchical complexity of tool use reported in non-human primates. An analysis of the patterns of object manipulation in naive chimpanzees after nut-cracking demonstrations revealed the cause of difficulties in learning nut-cracking behaviour. Various types of behaviours exhibited within a nut-cracking context can be examined in terms of the application of problem-solving strategies, focusing on their basis in causal understanding or insightful intentionality. Captive chimpanzees also exhibit complex forms of combinatory manipulation, which is the precursor of tool use. A new notation system of object manipulation was invented to assess grammatical rules in manipulative actions. The notation system of action grammar enabled direct comparisons to be made between primates including humans in a variety of object-manipulation tasks, including percussive-tool use. PMID:26483528

  7. Acquisition and replay systems for direct-to-digital holography and holovision

    DOEpatents

    Thomas, Clarence E.; Hanson, Gregory R.

    2003-02-25

    Improvements to the acquisition and replay systems for direct-to-digital holography and holovision are described. A method of recording an off-axis hologram includes: splitting a laser beam into an object beam and a reference beam; reflecting the reference beam from a reference beam mirror; reflecting the object beam from an illumination beamsplitter; passing the object beam through an objective lens; reflecting the object beam from an object; focusing the reference beam and the object beam at a focal plane of a digital recorder to form an off-axis hologram; digitally recording the off-axis hologram; and transforming the off-axis hologram in accordance with a Fourier transform to obtain a set of results. A method of writing an off-axis hologram includes: passing a laser beam through a spatial light modulator; and focusing the laser beam at a focal plane of a photorefractive crystal to impose a holographic diffraction grating pattern on the photorefractive crystal. A method of replaying an off-axis hologram includes: illuminating a photorefractive crystal having a holographic diffraction grating with a replay beam.

  8. Perspectives on object manipulation and action grammar for percussive actions in primates.

    PubMed

    Hayashi, Misato

    2015-11-19

    The skill of object manipulation is a common feature of primates including humans, although there are species-typical patterns of manipulation. Object manipulation can be used as a comparative scale of cognitive development, focusing on its complexity. Nut cracking in chimpanzees has the highest hierarchical complexity of tool use reported in non-human primates. An analysis of the patterns of object manipulation in naive chimpanzees after nut-cracking demonstrations revealed the cause of difficulties in learning nut-cracking behaviour. Various types of behaviours exhibited within a nut-cracking context can be examined in terms of the application of problem-solving strategies, focusing on their basis in causal understanding or insightful intentionality. Captive chimpanzees also exhibit complex forms of combinatory manipulation, which is the precursor of tool use. A new notation system of object manipulation was invented to assess grammatical rules in manipulative actions. The notation system of action grammar enabled direct comparisons to be made between primates including humans in a variety of object-manipulation tasks, including percussive-tool use. © 2015 The Author(s).

  9. Approach to an Affordable and Productive Space Transportation System

    NASA Technical Reports Server (NTRS)

    McCleskey, Carey M.; Rhodes, Russel E.; Lepsch, Roger A.; Henderson, Edward M.; Robinson, John W.

    2012-01-01

    This paper describes an approach for creating space transportation architectures that are affordable, productive, and sustainable. The architectural scope includes both flight and ground system elements, and focuses on their compatibility to achieve a technical solution that is operationally productive, and also affordable throughout its life cycle. Previous papers by the authors and other members of the Space Propulsion Synergy Team (SPST) focused on space flight system engineering methods, along with operationally efficient propulsion system concepts and technologies. This paper follows up previous work by using a structured process to derive examples of conceptual architectures that integrate a number of advanced concepts and technologies. The examples are not intended to provide a near-term alternative architecture to displace current near-term design and development activity. Rather, the examples demonstrate an approach that promotes early investments in advanced system concept studies and trades (flight and ground), as well as in advanced technologies with the goal of enabling highly affordable, productive flight and ground space transportation systems.

  10. A Doctor is in the House: Stakeholder Focus Groups About Expanded Scope of Practice of Community Psychiatrists.

    PubMed

    Mangurian, Christina; Modlin, Chelsea; Williams, Lindsey; Essock, Susan; Riano, Nicholas S; Shumway, Martha; Newcomer, John W; Dilley, James W; Schillinger, Dean

    2017-11-28

    We sought to understand stakeholder perspectives on barriers to metabolic screening for people with severe mental illness. We additionally assessed the feasibility of expanding psychiatrists' scope of practice to include treatment of cardiometabolic abnormalities. We conducted four focus groups among patients with severe mental illness, community psychiatrists, primary care providers, and public health administrators. Focus group transcripts were thematically analyzed. Three domains emerged: challenges with patient navigation of the complex health care system, problem list prioritization difficulties, and concern that treatment of cardiometabolic abnormalities were beyond the scope of practice of psychiatrists. Stakeholders agreed that navigating the health care system was challenging for this population and led to undertreatment of cardiometabolic risk factors. Expansion of psychiatrists' scope of practice within community mental health appears acceptable to patients and may be a mechanism to improve cardiometabolic care among people with severe mental illness.

  11. Vocational Psychology: An Analysis and Directions for the Future.

    ERIC Educational Resources Information Center

    Russell, Joyce E. A.

    2001-01-01

    Key areas of future research in vocational psychology include changing organizational structures, changing career attitudes, diversity of career development opportunities, international focus, increasing diversity, changing nature of technology, evolving educational systems, increased entrepreneurship, work and family issues, and career-leisure…

  12. Sherry Stout | NREL

    Science.gov Websites

    works on international programs where she focuses on grid integration of distributed renewable works on resilience issues including distributed generation and microgrids for energy system resilience Communities Water, Energy, Food Nexus Planning and Analysis Grid Integration of Distributed Generation

  13. Groundwater Interim Measures Work Plan for the Former Chemical Plant

    EPA Pesticide Factsheets

    May 2012 Groundwater IMWP, revised per EPA's approval, focuses on the installation of a groundwater containment system to mitigate groundwater migration from the former plant. A prior 2002 work plan is included in its entirety in Appendix B.

  14. Experiments on Interfaces To Support Query Expansion.

    ERIC Educational Resources Information Center

    Beaulieu, M.

    1997-01-01

    Focuses on the user and human-computer interaction aspects of the research based on the Okapi text retrieval system. Three experiments implementing different approaches to query expansion are described, including the use of graphical user interfaces with different windowing techniques. (Author/LRW)

  15. Peeking at the Planets.

    ERIC Educational Resources Information Center

    Riddle, Bob

    2002-01-01

    Provides information about each of the planets in our solar system. Focuses on information related to the space missions that have visited or flown near each planet, and includes a summary of what is known about some of the features of each planet. (DDR)

  16. Educational Reform in Spain.

    ERIC Educational Resources Information Center

    Marchesi, Alvaro

    1992-01-01

    Reviews the Spanish educational system, focusing on reforms enacted in 1990. Discusses reform movement issues, including quality, curricular control, curricular homogeneity versus diversity, and influence of European context. Describes reform movement aims (i.e., extending basic education and modifying educational levels to improve quality) and…

  17. Implementation of sustainable and green design and construction practices for bridges.

    DOT National Transportation Integrated Search

    2012-12-01

    The focus of this research is to develop a framework for more sustainable design and construction : processes for new bridges, and sustainable maintenance practices for existing bridges. The framework : includes a green rating system for bridges. The...

  18. 7 CFR 400.701 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ..., unique policy provisions or endorsements, the delivery process of the submission, and the process of... information is based, such data may include, but is not limited to, focus group results, market research studies, qualitative market estimates, effects upon the delivery system or ancillary participants...

  19. 7 CFR 400.701 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ..., unique policy provisions or endorsements, the delivery process of the submission, and the process of... information is based, such data may include, but is not limited to, focus group results, market research studies, qualitative market estimates, effects upon the delivery system or ancillary participants...

  20. 7 CFR 400.701 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ..., unique policy provisions or endorsements, the delivery process of the submission, and the process of... information is based, such data may include, but is not limited to, focus group results, market research studies, qualitative market estimates, effects upon the delivery system or ancillary participants...

  1. 7 CFR 400.701 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ..., unique policy provisions or endorsements, the delivery process of the submission, and the process of... information is based, such data may include, but is not limited to, focus group results, market research studies, qualitative market estimates, effects upon the delivery system or ancillary participants...

  2. Educational Systems Design Implications of Electronic Publishing.

    ERIC Educational Resources Information Center

    Romiszowski, Alexander J.

    1994-01-01

    Discussion of electronic publishing focuses on the four main purposes of media in general: communication, entertainment, motivation, and education. Highlights include electronic journals and books; hypertext; user control; computer graphics and animation; electronic games; virtual reality; multimedia; electronic performance support;…

  3. E-Moderating Personas

    ERIC Educational Resources Information Center

    Avgerinou, Maria D.; Andersson, Carina

    2007-01-01

    Web-based distance education has become a "real" teaching alternative which has instigated more research particularly in the past decade. This research has commonly focused on four major perspectives: (1) information-technology; (2) course management systems (including course communication tools); (3) information design; and (4) online…

  4. Align the Front End First.

    ERIC Educational Resources Information Center

    Perry, Jim

    1995-01-01

    Discussion of management styles and front-end analysis focuses on a review of Douglas McGregor's theories. Topics include Theories X, Y, and Z; leadership skills; motivational needs of employees; intrinsic and extrinsic rewards; and faulty implementation of instructional systems design processes. (LRW)

  5. NASA Tech Briefs, December 1995. Volume 19, No. 12

    NASA Technical Reports Server (NTRS)

    1995-01-01

    Topics include: a special focus section on Bio/Medical technology, electronic components and circuits, electronic systems, physical sciences, materials, computer programs, mechanics, machinery, manufacturing/fabrication, mathematics and information sciences, book and reports, and a special section on Laser Tech Briefs.

  6. Libraries on the MOVE.

    ERIC Educational Resources Information Center

    Edgar, Jim; And Others

    1986-01-01

    Presents papers from Illinois State Library and Shawnee Library System's "Libraries on the MOVE" conference focusing on how libraries can impact economic/cultural climate of an area. Topics addressed included information services of rural libraries; marketing; rural library development; library law; information access; interagency…

  7. Mutagenicity of Cookstove Emissions

    EPA Science Inventory

    The presentation by David DeMarini will focus on emission factors, including mutagenicity, for 3 stoves. It will correlate the emission factors to assess the health safety of the stove systems and place the mutagenicity emission factor in context with that of other combustion em...

  8. Timescales and the management of ecological systems.

    PubMed

    Hastings, Alan

    2016-12-20

    Human management of ecological systems, including issues like fisheries, invasive species, and restoration, as well as others, often must be undertaken with limited information. This means that developing general principles and heuristic approaches is important. Here, I focus on one aspect, the importance of an explicit consideration of time, which arises because of the inherent limitations in the response of ecological systems. I focus mainly on simple systems and models, beginning with systems without density dependence, which are therefore linear. Even for these systems, it is important to recognize the necessary delays in the response of the ecological system to management. Here, I also provide details for optimization that show how general results emerge and emphasize how delays due to demography and life histories can change the optimal management approach. A brief discussion of systems with density dependence and tipping points shows that the same themes emerge, namely, that when considering issues of restoration or management to change the state of an ecological system, that timescales need explicit consideration and may change the optimal approach in important ways.

  9. Development of an Instrument for Assessing the Effectiveness of Chemistry Classroom Teaching

    NASA Astrophysics Data System (ADS)

    Zheng, Changlong; Fu, Lihai; He, Peng

    2014-04-01

    Classroom teaching is a main frontier of the implementation of new curricular ideas in China. The study reported in this article is concerned with the effectiveness of system of classroom teaching (SCT) in chemistry lessons. According to the Systems Science theory, we took a macroscopic view on the SCT, arguing that SCT is a hierarchy of system, which includes class system, plate system, unit system, and primitive system. In this study, we focused on primitive system of classroom teaching (PrS)—the lowest level in a SCT. Using focus group interviews, this study investigated the variables related to the effectiveness of PrS. We found a total of 21 such variables. To identify the main factors underlying the effectiveness of PrS, we further used exploratory factor analysis and confirmatory factor analysis. We found five main factors: rational use of time, quality of teaching behavior chain, match degree, quality of using resource and technology, and rationality of primitive content. Based on these findings, we constructed an evaluation scale for assessing the effectiveness of primitive system of chemistry classroom teaching.

  10. IT in the ED: a new section of Pediatric Emergency Care.

    PubMed

    Zorc, Joseph J; Hoffman, Jeffrey M; Harper, Marvin B

    2012-12-01

    Information technology (IT) has profoundly changed the delivery of health care during the past decade. The pediatric emergency department (ED) represents a specific challenge for applying IT systems to the patient bedside. The rapid pace and unscheduled nature of the ED, the breadth of care delivered, and the range of medical, ethical, cultural, and process issues presented by pediatric patients make this a setting in particular need of thoughtfully designed and usable IT systems. However, reviews of the current state of health IT have documented mixed outcomes, including safety risks introduced by IT systems, significant deficits in usability for clinicians, and unrealized potential. Although some publications have presented methods and outcomes of IT systems in the pediatric ED, the current medical literature is sparse. Professional organizations have not developed successful methods to share best practices across institutions and IT vendors. The authors propose a new section of this journal focused on the application of IT systems to Pediatric Emergency Care. The section will include original research articles and reviews focusing on the application of IT to improve care of acutely ill and injured children. Innovative approaches and articles by physicians in training are particularly encouraged to develop new expertise in informatics within this and related specialties.

  11. Advanced Reactor PSA Methodologies for System Reliability Analysis and Source Term Assessment

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Grabaskas, D.; Brunett, A.; Passerini, S.

    Beginning in 2015, a project was initiated to update and modernize the probabilistic safety assessment (PSA) of the GE-Hitachi PRISM sodium fast reactor. This project is a collaboration between GE-Hitachi and Argonne National Laboratory (Argonne), and funded in part by the U.S. Department of Energy. Specifically, the role of Argonne is to assess the reliability of passive safety systems, complete a mechanistic source term calculation, and provide component reliability estimates. The assessment of passive system reliability focused on the performance of the Reactor Vessel Auxiliary Cooling System (RVACS) and the inherent reactivity feedback mechanisms of the metal fuel core. Themore » mechanistic source term assessment attempted to provide a sequence specific source term evaluation to quantify offsite consequences. Lastly, the reliability assessment focused on components specific to the sodium fast reactor, including electromagnetic pumps, intermediate heat exchangers, the steam generator, and sodium valves and piping.« less

  12. Joint System Prognostics For Increased Efficiency And Risk Mitigation In Advanced Nuclear Reactor Instrumentation and Control

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Donald D. Dudenhoeffer; Tuan Q. Tran; Ronald L. Boring

    2006-08-01

    The science of prognostics is analogous to a doctor who, based on a set of symptoms and patient tests, assesses a probable cause, the risk to the patient, and a course of action for recovery. While traditional prognostics research has focused on the aspect of hydraulic and mechanical systems and associated failures, this project will take a joint view in focusing not only on the digital I&C aspect of reliability and risk, but also on the risks associated with the human element. Model development will not only include an approximation of the control system physical degradation but also on humanmore » performance degradation. Thus the goal of the prognostic system is to evaluate control room operation; to identify and potentially take action when performance degradation reduces plant efficiency, reliability or safety.« less

  13. Adaptation and Implementation of a Science-Based Prevention System in Colombia: Challenges and Achievements

    PubMed Central

    Pérez-Gómez, Augusto; Mejía-Trujillo, Juliana; Brown, Eric C.; Eisenberg, Nicole

    2016-01-01

    During the last 2 years, the Colombian government and the Nuevos Rumbos Corporation have been implementing an adapted version of the Communities That Care (CTC) prevention system, called Comunidades Que se Cuidan (CQC) in Spanish, for use in Colombia. This brief report presents the process of implementing CQC and identifies some of the main challenges and achievements of implementing the system in eight communities in Colombia. Preliminary results of a pilot study of CQC implementation in Colombia show that prevention system development, including a focus on measuring community risk and protection, can be established successfully in Latin American communities despite a lack of rigorously tested prevention programs and strategies. Moreover, mobilizing community coalitions toward science-based prevention, with a focus on examining local risk and protective factor data, can spur development and evaluation of prevention efforts in Latin America. PMID:28154437

  14. RNA Systems Biology for Cancer: From Diagnosis to Therapy.

    PubMed

    Amirkhah, Raheleh; Farazmand, Ali; Wolkenhauer, Olaf; Schmitz, Ulf

    2016-01-01

    It is due to the advances in high-throughput omics data generation that RNA species have re-entered the focus of biomedical research. International collaborate efforts, like the ENCODE and GENCODE projects, have spawned thousands of previously unknown functional non-coding RNAs (ncRNAs) with various but primarily regulatory roles. Many of these are linked to the emergence and progression of human diseases. In particular, interdisciplinary studies integrating bioinformatics, systems biology, and biotechnological approaches have successfully characterized the role of ncRNAs in different human cancers. These efforts led to the identification of a new tool-kit for cancer diagnosis, monitoring, and treatment, which is now starting to enter and impact on clinical practice. This chapter is to elaborate on the state of the art in RNA systems biology, including a review and perspective on clinical applications toward an integrative RNA systems medicine approach. The focus is on the role of ncRNAs in cancer.

  15. Endocannabinoids and neuropathic pain: focus on neuron-glia and endocannabinoid-neurotrophin interactions.

    PubMed

    Luongo, Livio; Maione, Sabatino; Di Marzo, Vincenzo

    2014-02-01

    Although originally described as a signalling system encompassing the cannabinoid CB1 and CB2 receptors, their endogenous agonists (the endocannabinoids), and metabolic enzymes regulating the levels of such agonists, the endocannabinoid system is now viewed as being more complex, and including metabolically related endocannabinoid-like mediators and their molecular targets as well. The function and dysfunction of this complex signalling system in the molecular and cellular mechanisms of pain transduction and control has been widely studied over the last two decades. In this review article, we describe some of the latest advances in our knowledge on the role of the endocannabinoid system, in its most recent and wider conception, in pain pathways, by focusing on: (1) neuron-glia interactions; and (2) emerging data on endocannabinoid cross-talk with neurotrophins, such as nerve growth factor and brain-derived neurotrophic factor. © 2014 Federation of European Neuroscience Societies and John Wiley & Sons Ltd.

  16. Microsystem enabled photovoltaic modules and systems

    DOEpatents

    Nielson, Gregory N; Sweatt, William C; Okandan, Murat

    2015-05-12

    A microsystem enabled photovoltaic (MEPV) module including: an absorber layer; a fixed optic layer coupled to the absorber layer; a translatable optic layer; a translation stage coupled between the fixed and translatable optic layers; and a motion processor electrically coupled to the translation stage to controls motion of the translatable optic layer relative to the fixed optic layer. The absorber layer includes an array of photovoltaic (PV) elements. The fixed optic layer includes an array of quasi-collimating (QC) micro-optical elements designed and arranged to couple incident radiation from an intermediate image formed by the translatable optic layer into one of the PV elements such that it is quasi-collimated. The translatable optic layer includes an array of focusing micro-optical elements corresponding to the QC micro-optical element array. Each focusing micro-optical element is designed to produce a quasi-telecentric intermediate image from substantially collimated radiation incident within a predetermined field of view.

  17. Towards a definition of orphaned and vulnerable children.

    PubMed

    Skinner, Donald; Tsheko, N; Mtero-Munyati, S; Segwabe, M; Chibatamoto, P; Mfecane, S; Chandiwana, B; Nkomo, N; Tlou, S; Chitiyo, G

    2006-11-01

    The HIV epidemic presents challenges including orphans and a large mass of children rendered vulnerable by the epidemic and other societal forces. Focus on orphaned and vulnerable children (OVC) is important, but needs accurate definition. Twelve focus group interviews of service providers, leaders in these communities, OVC and their caretakers were conducted at six project sites across Botswana, South Africa and Zimbabwe to extend this definition. The loss of a parent through death or desertion is an important aspect of vulnerability. Additional factors leading to vulnerability included severe chronic illness of a parent or caregiver, poverty, hunger, lack of access to services, inadequate clothing or shelter, overcrowding, deficient caretakers, and factors specific to the child, including disability, direct experience of physical or sexual violence, or severe chronic illness. Important questions raised in this research include the long-term implications for the child and community, and the contribution of culture systems.

  18. The dynamics of software development project management: An integrative systems dynamic perspective

    NASA Technical Reports Server (NTRS)

    Vandervelde, W. E.; Abdel-Hamid, T.

    1984-01-01

    Rather than continuing to focus on software development projects per se, the system dynamics modeling approach outlined is extended to investigate a broader set of issues pertaining to the software development organization. Rather than trace the life cycle(s) of one or more software projects, the focus is on the operations of a software development department as a continuous stream of software products are developed, placed into operation, and maintained. A number of research questions are ""ripe'' for investigating including: (1) the efficacy of different organizational structures in different software development environments, (2) personnel turnover, (3) impact of management approaches such as management by objectives, and (4) the organizational/environmental determinants of productivity.

  19. MICADO: first light imager for the E-ELT

    NASA Astrophysics Data System (ADS)

    Davies, R.; Schubert, J.; Hartl, M.; Alves, J.; Clénet, Y.; Lang-Bardl, F.; Nicklas, H.; Pott, J.-U.; Ragazzoni, R.; Tolstoy, E.; Agocs, T.; Anwand-Heerwart, H.; Barboza, S.; Baudoz, P.; Bender, R.; Bizenberger, P.; Boccaletti, A.; Boland, W.; Bonifacio, P.; Briegel, F.; Buey, T.; Chapron, F.; Cohen, M.; Czoske, O.; Dreizler, S.; Falomo, R.; Feautrier, P.; Förster Schreiber, N.; Gendron, E.; Genzel, R.; Glück, M.; Gratadour, D.; Greimel, R.; Grupp, F.; Häuser, M.; Haug, M.; Hennawi, J.; Hess, H. J.; Hörmann, V.; Hofferbert, R.; Hopp, U.; Hubert, Z.; Ives, D.; Kausch, W.; Kerber, F.; Kravcar, H.; Kuijken, K.; Lang-Bardl, F.; Leitzinger, M.; Leschinski, K.; Massari, D.; Mei, S.; Merlin, F.; Mohr, L.; Monna, A.; Müller, F.; Navarro, R.; Plattner, M.; Przybilla, N.; Ramlau, R.; Ramsay, S.; Ratzka, T.; Rhode, P.; Richter, J.; Rix, H.-W.; Rodeghiero, G.; Rohloff, R.-R.; Rousset, G.; Ruddenklau, R.; Schaffenroth, V.; Schlichter, J.; Sevin, A.; Stuik, R.; Sturm, E.; Thomas, J.; Tromp, N.; Turatto, M.; Verdoes-Kleijn, G.; Vidal, F.; Wagner, R.; Wegner, M.; Zeilinger, W.; Ziegler, B.; Zins, G.

    2016-08-01

    MICADO will equip the E-ELT with a first light capability for diffraction limited imaging at near-infrared wavelengths. The instrument's observing modes focus on various flavours of imaging, including astrometric, high contrast, and time resolved. There is also a single object spectroscopic mode optimised for wavelength coverage at moderately high resolution. This contribution provides an overview of the key functionality of the instrument, outlining the scientific rationale for its observing modes. The interface between MICADO and the adaptive optics system MAORY that feeds it is summarised. The design of the instrument is discussed, focusing on the optics and mechanisms inside the cryostat, together with a brief overview of the other key sub-systems.

  20. Study of Plasma Flows Generated in Plasma Focus Discharge in Different Regimes of Working Gas Filling

    NASA Astrophysics Data System (ADS)

    Voitenko, D. A.; Ananyev, S. S.; Astapenko, G. I.; Basilaia, A. D.; Markolia, A. I.; Mitrofanov, K. N.; Myalton, V. V.; Timoshenko, A. P.; Kharrasov, A. M.; Krauz, V. I.

    2017-12-01

    Results are presented from experimental studies of the plasma flows generated in the KPF-4 Phoenix Mather-type plasma focus device (Sukhum Physical Technical Institute). In order to study how the formation and dynamics of the plasma flow depend on the initial distribution of the working gas, a system of pulsed gas puffing into the discharge volume was developed. The system allows one to create profiled gas distributions, including those with a reduced gas density in the region of plasma flow propagation. Results of measurements of the magnetic field, flow profile, and flow deceleration dynamics at different initial distributions of the gas pressure are presented.

  1. Discovery Channel Telescope active optics system early integration and test

    NASA Astrophysics Data System (ADS)

    Venetiou, Alexander J.; Bida, Thomas A.

    2012-09-01

    The Discovery Channel Telescope (DCT) is a 4.3-meter telescope with a thin meniscus primary mirror (M1) and a honeycomb secondary mirror (M2). The optical design is an f/6.1 Ritchey-Chrétien (RC) with an unvignetted 0.5° Field of View (FoV) at the Cassegrain focus. We describe the design, implementation and performance of the DCT active optics system (AOS). The DCT AOS maintains collimation and controls the figure of the mirror to provide seeing-limited images across the focal plane. To minimize observing overhead, rapid settling times are achieved using a combination of feed-forward and low-bandwidth feedback control using a wavefront sensing system. In 2011, we mounted a Shack-Hartmann wavefront sensor at the prime focus of M1, the Prime Focus Test Assembly (PFTA), to test the AOS with the wavefront sensor, and the feedback loop. The incoming wavefront is decomposed using Zernike polynomials, and the mirror figure is corrected with a set of bending modes. Components of the system that we tested and tuned included the Zernike to Bending Mode transformations. We also started open-loop feed-forward coefficients determination. In early 2012, the PFTA was replaced by M2, and the wavefront sensor moved to its normal location on the Cassegrain instrument assembly. We present early open loop wavefront test results with the full optical system and instrument cube, along with refinements to the overall control loop operating at RC Cassegrain focus.

  2. Monitoring environmental hazards and public health

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    Saying that no national system exists to monitor public health problems linked to environmental hazards, former U.S. Senator Lowell Weicker, Jr., announced on May 11 the launch of a Pew Charitable Trusts blue ribbon panel to focus on this issue.The panel, which includes representatives from academia and health care organizations, will focus on how the United States tracks diseases and recommend ways to fill data gaps; review what tools are needed to improve disease tracking; and focus on children's health issues, such as asthma, childhood cancer, and birth defects that may be linked to the environment, according to Pew Environmental Health Commission Executive Director Shelley Hearne.

  3. How do we Remain Us in a Time of Change: Culture and Knowledge Management at NASA

    NASA Technical Reports Server (NTRS)

    Linde, Charlotte

    2003-01-01

    This viewgraph representation presents an overview of findings of a NASA agency-wide Knowledge Management Team considering culture and knowledge management issues at the agency. Specific issues identified by the team include: (1) NASA must move from being a knowledge hoarding culture to a knowledge sharing culture; (2) NASA must move from being center focused to being Agency focused; (3) NASA must capture the knowledge of a departing workforce. Topics considered include: what must NASA know to remain NASA, what were previous forms of knowledge reproduction and how has technological innovations changed these systems, and what changes in funding and relationships between contractors and NASA affected knowledge reproduction.

  4. Ubiquitous Wireless Smart Sensing and Control

    NASA Technical Reports Server (NTRS)

    Wagner, Raymond

    2013-01-01

    Need new technologies to reliably and safely have humans interact within sensored environments (integrated user interfaces, physical and cognitive augmentation, training, and human-systems integration tools). Areas of focus include: radio frequency identification (RFID), motion tracking, wireless communication, wearable computing, adaptive training and decision support systems, and tele-operations. The challenge is developing effective, low cost/mass/volume/power integrated monitoring systems to assess and control system, environmental, and operator health; and accurately determining and controlling the physical, chemical, and biological environments of the areas and associated environmental control systems.

  5. Ubiquitous Wireless Smart Sensing and Control. Pumps and Pipes JSC: Uniquely Houston

    NASA Technical Reports Server (NTRS)

    Wagner, Raymond

    2013-01-01

    Need new technologies to reliably and safely have humans interact within sensored environments (integrated user interfaces, physical and cognitive augmentation, training, and human-systems integration tools).Areas of focus include: radio frequency identification (RFID), motion tracking, wireless communication, wearable computing, adaptive training and decision support systems, and tele-operations. The challenge is developing effective, low cost/mass/volume/power integrated monitoring systems to assess and control system, environmental, and operator health; and accurately determining and controlling the physical, chemical, and biological environments of the areas and associated environmental control systems.

  6. Opto-mechanical design of the G-CLEF flexure control camera system

    NASA Astrophysics Data System (ADS)

    Oh, Jae Sok; Park, Chan; Kim, Jihun; Kim, Kang-Min; Chun, Moo-Young; Yu, Young Sam; Lee, Sungho; Nah, Jakyoung; Park, Sung-Joon; Szentgyorgyi, Andrew; McMuldroch, Stuart; Norton, Timothy; Podgorski, William; Evans, Ian; Mueller, Mark; Uomoto, Alan; Crane, Jeffrey; Hare, Tyson

    2016-08-01

    The GMT-Consortium Large Earth Finder (G-CLEF) is the very first light instrument of the Giant Magellan Telescope (GMT). The G-CLEF is a fiber feed, optical band echelle spectrograph that is capable of extremely precise radial velocity measurement. KASI (Korea Astronomy and Space Science Institute) is responsible for Flexure Control Camera (FCC) included in the G-CLEF Front End Assembly (GCFEA). The FCC is a kind of guide camera, which monitors the field images focused on a fiber mirror to control the flexure and the focus errors within the GCFEA. The FCC consists of five optical components: a collimator including triple lenses for producing a pupil, neutral density filters allowing us to use much brighter star as a target or a guide, a tent prism as a focus analyzer for measuring the focus offset at the fiber mirror, a reimaging camera with three pair of lenses for focusing the beam on a CCD focal plane, and a CCD detector for capturing the image on the fiber mirror. In this article, we present the optical and mechanical FCC designs which have been modified after the PDR in April 2015.

  7. Assessment of distributed photovoltair electric-power systems

    NASA Astrophysics Data System (ADS)

    Neal, R. W.; Deduck, P. F.; Marshall, R. N.

    1982-10-01

    The development of a methodology to assess the potential impacts of distributed photovoltaic (PV) systems on electric utility systems, including subtransmission and distribution networks, and to apply that methodology to several illustrative examples was developed. The investigations focused upon five specific utilities. Impacts upon utility system operations and generation mix were assessed using accepted utility planning methods in combination with models that simulate PV system performance and life cycle economics. Impacts on the utility subtransmission and distribution systems were also investigated. The economic potential of distributed PV systems was investigated for ownership by the utility as well as by the individual utility customer.

  8. Sustainability of knowledge translation interventions in healthcare decision-making: a scoping review.

    PubMed

    Tricco, Andrea C; Ashoor, Huda M; Cardoso, Roberta; MacDonald, Heather; Cogo, Elise; Kastner, Monika; Perrier, Laure; McKibbon, Ann; Grimshaw, Jeremy M; Straus, Sharon E

    2016-04-21

    Knowledge translation (KT, also known as research utilization, and sometimes referring to implementation science) is a dynamic and iterative process that includes the synthesis, dissemination, exchange, and ethically sound application of knowledge to improve health. A KT intervention is one which facilitates the uptake of research. The long-term sustainability of KT interventions is unclear. We aimed to characterize KT interventions to manage chronic diseases that have been used for healthcare outcomes beyond 1 year or beyond the termination of initial grant funding. We conducted a scoping review by searching MEDLINE, Embase, Cochrane Central Register of Controlled Trials (CENTRAL), Cumulative Index to Nursing and Allied Health Literature (CINAHL), and Campbell from inception until February 2013. We included experimental, quasi-experimental, and observational studies providing information on the sustainability of KT interventions for managing chronic diseases in adults and focusing on end-users including patients, clinicians, public health officials, health service managers, and policy-makers. Articles were screened and abstracted by two reviewers, independently. The data were charted and results described narratively. We included 62 studies reported in 103 publications (total 260,688 patients) plus 41 companion reports after screening 12,328 titles and abstracts and 464 full-text articles. More than half of the studies were randomized controlled trials (RCTs). The duration of the KT intervention ranged from 61 to 522 weeks. Nine chronic conditions were examined across the studies, such as diabetes (34 %), cardiovascular disease (28 %), and hypertension (16 %). Thirteen KT interventions were reported across the studies. Patient education was the most commonly examined (20 %), followed by self-management (17 %). Most studies (61 %) focused on patient-level outcomes (e.g. disease severity), while 31 % included system-level outcomes (e.g. number of eye examinations), and 8 % used both. The interventions were aimed at the patient (58 %), health system (28 %), and healthcare personnel (14 %) levels. We found few studies focusing on the sustainability of KT interventions. Most of the included studies focused on patient-level outcomes and patient-level KT interventions. A future systematic review can be conducted of the RCTs to examine the impact of sustainable KT interventions on health outcomes.

  9. Lifecycle assessment of microalgae to biofuel: Comparison of thermochemical processing pathways

    DOE PAGES

    Bennion, Edward P.; Ginosar, Daniel M.; Moses, John; ...

    2015-01-16

    Microalgae are currently being investigated as a renewable transportation fuel feedstock based on various advantages that include high annual yields, utilization of poor quality land, does not compete with food, and can be integrated with various waste streams. This study focuses on directly assessing the impact of two different thermochemical conversion technologies on the microalgae to biofuel process through life cycle assessment. A system boundary of a “well to pump” (WTP) is defined and includes sub-process models of the growth, dewatering, thermochemical bio-oil recovery, bio-oil stabilization, conversion to renewable diesel, and transport to the pump. Models were validated with experimentalmore » and literature data and are representative of an industrial-scale microalgae to biofuel process. Two different thermochemical bio-oil conversion systems are modeled and compared on a systems level, hydrothermal liquefaction (HTL) and pyrolysis. The environmental impact of the two pathways were quantified on the metrics of net energy ratio (NER), defined here as energy consumed over energy produced, and greenhouse gas (GHG) emissions. Results for WTP biofuel production through the HTL pathway were determined to be 1.23 for the NER and GHG emissions of -11.4 g CO 2-eq (MJ renewable diesel) -1. WTP biofuel production through the pyrolysis pathway results in a NER of 2.27 and GHG emissions of 210 g CO2 eq (MJ renewable diesel)-1. The large environmental impact associated with the pyrolysis pathway is attributed to feedstock drying requirements and combustion of co-products to improve system energetics. Discussion focuses on a detailed breakdown of the overall process energetics and GHGs, impact of modeling at laboratory- scale compared to industrial-scale, environmental impact sensitivity to engineering systems input parameters for future focused research and development and a comparison of results to literature.« less

  10. Life cycle assessment of microalgae to biofuel: Thermochemical processing through hydrothermal liquefaction or pyrolysis

    NASA Astrophysics Data System (ADS)

    Bennion, Edward P.

    Microalgae are currently being investigated as a renewable transportation fuel feedstock based on various advantages that include high annual yields, utilization of poor quality land, does not compete with food, and can be integrated with various waste streams. This study focuses on directly assessing the impact of two different thermochemical conversion technologies on the microalgae-to-biofuel process through life cycle assessment. A system boundary of a "well to pump" (WTP) is defined and includes sub-process models of the growth, dewatering, thermochemical bio-oil recovery, bio-oil stabilization, conversion to renewable diesel, and transport to the pump. Models were validated with experimental and literature data and are representative of an industrial-scale microalgae-to-biofuel process. Two different thermochemical bio-oil conversion systems are modeled and compared on a systems level, hydrothermal liquefaction (HTL) and pyrolysis. The environmental impact of the two pathways were quantified on the metrics of net energy ratio (NER), defined here as energy consumed over energy produced, and greenhouse gas (GHG) emissions. Results for WTP biofuel production through the HTL pathway were determined to be 1.23 for the NER and GHG emissions of -11.4 g CO2 eq (MJ renewable diesel)-1. WTP biofuel production through the pyrolysis pathway results in a NER of 2.27 and GHG emissions of 210 g CO2 eq (MJ renewable diesel)-1. The large environmental impact associated with the pyrolysis pathway is attributed to feedstock drying requirements and combustion of co-products to improve system energetics. Discussion focuses on a detailed breakdown of the overall process energetics and GHGs, impact of modeling at laboratory-scale compared to industrial-scale, environmental impact sensitivity to engineering systems input parameters for future focused research and development, and a comparison of results to literature.

  11. Initiating a Standardized Regional Referral and Counter-Referral System in Guatemala: A Mixed-Methods Study.

    PubMed

    Kapoor, Rupa; Avendaño, Leslie; Sandoval, Maria Antonieta; Cruz, Andrea T; Sampayo, Esther M; Soto, Miguel A; Camp, Elizabeth A; Crouse, Heather L

    2017-01-01

    Background: Few data exist for referral processes in resource-limited settings. We utilized mixed-methods to evaluate the impact of a standardized algorithm and training module developed for locally identified needs in referral/counter-referral procedures between primary health centers (PHCs) and a Guatemalan referral hospital. Methods : PHC personnel and hospital physicians participated in surveys and focus groups pre-implementation and 3, 6, and 12 months post-implementation to evaluate providers' experience with the system. Referred patient records were reviewed to evaluate system effectiveness. Results : A total of 111 initial focus group participants included 96 (86.5%) from PHCs and 15 from the hospital. Of these participants, 53 PHC physicians and nurses and 15 hospital physicians initially completed written surveys. Convenience samples participated in follow-up. Eighteen focus groups achieved thematic saturation. Four themes emerged: effective communication; provision of timely, quality patient care with adequate resources; educational opportunities; and development of empowerment and relationships. Pre- and post-implementation surveys demonstrated significant improvement at the PHCs ( P < .001) and the hospital ( P = .02). Chart review included 435 referrals, 98 (22.5%) pre-implementation and 337 (77.5%) post-implementation. There was a trend toward an increased percentage of appropriately referred patients requiring medical intervention (30% vs 40%, P = .08) and of patients requiring intervention who received it prior to transport (55% vs 73%, P = .06). Conclusions : Standardizing a referral/counter-referral system improved communication, education, and trust across different levels of pediatric health care delivery. This model may be used for extension throughout Guatemala or be modified for use in other countries. Mixed-methods research design can evaluate complex systems in resource-limited settings.

  12. A Qualitative Analysis of NASA’s Human Computer Interaction Group Examining the Root Causes of Focusing on Derivative System Improvements Versus Core User Needs

    DTIC Science & Technology

    2017-12-01

    emphasis on meeting deliverable dates over a focus on customer service and user experience, a common finding in McGrath and MacMillan’s (2000) research...including suggestions for reducing this burden, to Washington headquarters Services , Directorate for Information Operations and Reports, 1215...structure, process improvements, and training needs as the group prepares to support the retirement of the International Space Station in the 2020s and

  13. A low cost, adaptive mixed reality system for home-based stroke rehabilitation.

    PubMed

    Chen, Yinpeng; Baran, Michael; Sundaram, Hari; Rikakis, Thanassis

    2011-01-01

    This paper presents a novel, low-cost, real-time adaptive multimedia environment for home-based upper extremity rehabilitation of stroke survivors. The primary goal of this system is to provide an interactive tool with which the stroke survivor can sustain gains achieved within the clinical phase of therapy and increase the opportunity for functional recovery. This home-based mediated system has low cost sensing, off the shelf components for the auditory and visual feedback, and remote monitoring capability. The system is designed to continue active learning by reducing dependency on real-time feedback and focusing on summary feedback after a single task and sequences of tasks. To increase system effectiveness through customization, we use data from the training strategy developed by the therapist at the clinic for each stroke survivor to drive automated system adaptation at the home. The adaptation includes changing training focus, selecting proper feedback coupling both in real-time and in summary, and constructing appropriate dialogues with the stroke survivor to promote more efficient use of the system. This system also allows the therapist to review participant's progress and adjust the training strategy weekly.

  14. Mass spectrometry-based proteomic exploration of the human immune system: focus on the inflammasome, global protein secretion, and T cells.

    PubMed

    Nyman, Tuula A; Lorey, Martina B; Cypryk, Wojciech; Matikainen, Sampsa

    2017-05-01

    The immune system is our defense system against microbial infections and tissue injury, and understanding how it works in detail is essential for developing drugs for different diseases. Mass spectrometry-based proteomics can provide in-depth information on the molecular mechanisms involved in immune responses. Areas covered: Summarized are the key immunology findings obtained with MS-based proteomics in the past five years, with a focus on inflammasome activation, global protein secretion, mucosal immunology, immunopeptidome and T cells. Special focus is on extracellular vesicle-mediated protein secretion and its role in immune responses. Expert commentary: Proteomics is an essential part of modern omics-scale immunology research. To date, MS-based proteomics has been used in immunology to study protein expression levels, their subcellular localization, secretion, post-translational modifications, and interactions in immune cells upon activation by different stimuli. These studies have made major contributions to understanding the molecular mechanisms involved in innate and adaptive immune responses. New developments in proteomics offer constantly novel possibilities for exploring the immune system. Examples of these techniques include mass cytometry and different MS-based imaging approaches which can be widely used in immunology.

  15. Sustainable intensification by managing microbial communities and processes in agroecosystems

    USDA-ARS?s Scientific Manuscript database

    By focusing on soil biology and biochemistry, agroecosystem management strategies are implemented which include reduced soil disturbance, diverse and adaptable crop rotations, retention of residue, and incorporation of livestock, cover crops, or both This systems approach is required to sustainably ...

  16. Final Project Report to NSF.

    ERIC Educational Resources Information Center

    National Inst. for Science Education, Madison, WI.

    The National Institute for Science Education's (NISE) focused mission is to improve mathematics and science education from kindergarten through college. This document reports on NISE's research programs, dissemination programs, and organizational process programs. Contents include: (1) "Systemic Reform: Policy and Evaluation" (William H. Clune and…

  17. Brave New World: Frontware, Megabytes, and Integrated Systems.

    ERIC Educational Resources Information Center

    McIntyre, Jim

    1991-01-01

    Several experts in the field of college financial administration offer their insights into the emerging relationship between high technology and financial management, focusing on the role of the institution's chief business officer. Topics include efficiency, cost effectiveness, organizational communication, homegrown vs. packaged software…

  18. Persons with Diet-Related Diseases.

    ERIC Educational Resources Information Center

    McNutt, Kristen W.; Steinberg, Louis H.

    1980-01-01

    This article focuses on the educational approach to dealing with people with diet related diseases, their prevention, detection, and treatment. Issues include content and goals of education, identification of factors affecting food choices, professional education improvement, coordination of nutrition education systems, and nutrition concerns. (SA)

  19. Field Demonstration of Multi-Sensor Technology for Condition Assessment of Wastewater Collection Systems (Abstract)

    EPA Science Inventory

    The purpose of the field demonstration program is to gather technically reliable cost and performance information on selected condition assessment technologies under defined field conditions. The selected technologies include zoom camera, focused electrode leak location (FELL), ...

  20. Teaching Materials and Methods.

    ERIC Educational Resources Information Center

    Physiologist, 1982

    1982-01-01

    Twelve abstracts of papers presented at the 33rd Annual Fall Meeting of the American Physiological Society are listed, focusing on teaching materials/methods. Topics, among others, include trends in physiology laboratory programs, cardiovascular system model, cardiovascular computer simulation with didactic feedback, and computer generated figures…

  1. The Japan of Today, 1982.

    ERIC Educational Resources Information Center

    Ministry of Foreign Affairs, Tokyo (Japan).

    Following an introduction which discusses the history and geography of Japan, this book focuses on topics related to this country's government, economy, social conditions, and cultural life. Topics related to government include: constitution and emperor; legislature; executive power; judiciary system; foreign relations; and defense. Topics related…

  2. Help! Our Camp Enrollment Is Down.

    ERIC Educational Resources Information Center

    Post, Peter

    1993-01-01

    Describes a marketing plan to increase enrollment in summer camps. Includes analyzing enrollment statistics, implementing marketing strategies that focus on retaining current campers, establishing a ranking system to concentrate efforts on inquiries most likely to enroll, and analyzing the effectiveness of marketing strategies. (LP)

  3. A comparison of bareroot and containerized seedling production

    Treesearch

    John McRae; Tom Starkey

    2002-01-01

    Most nursery managers and culturists are comfortable growing bareroot seedlings. A few have become comfortable growing containerized seedlings. This discussion will compare the two systems, with a focus on SYP production, and will include a discussion on capital, equipment, space, and personnel requirements.

  4. Goal Translation: How To Create a Results-Focused Organizational Culture.

    ERIC Educational Resources Information Center

    Mourier, Pierre

    2000-01-01

    Presents a model for changing human and organizational behavior. Highlights include behavioral dynamics; expectations; alignment; organizational structure; organizational culture; individual skills and training; leadership; management systems; developing corporate-level goals; communicating goals to the organization; and developing employee goals.…

  5. Modeling Climate Dynamically

    ERIC Educational Resources Information Center

    Walsh, Jim; McGehee, Richard

    2013-01-01

    A dynamical systems approach to energy balance models of climate is presented, focusing on low order, or conceptual, models. Included are global average and latitude-dependent, surface temperature models. The development and analysis of the differential equations and corresponding bifurcation diagrams provides a host of appropriate material for…

  6. Power requirements for commercial communications spacecraft

    NASA Technical Reports Server (NTRS)

    Billerbeck, W. J.

    1985-01-01

    Historical data on commercial spacecraft power systems are presented and their power requirements to the growth of satellite communications channel usage are related. Some approaches for estimating future power requirements of this class of spacecraft through the year 2000 are proposed. The key technology drivers in satellite power systems are addressed. Several technological trends in such systems are described, focusing on the most useful areas for research and development of major subsystems, including solar arrays, energy storage, and power electronics equipment.

  7. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Grabaskas, David; Brunett, Acacia J.; Passerini, Stefano

    GE Hitachi Nuclear Energy (GEH) and Argonne National Laboratory (Argonne) participated in a two year collaboration to modernize and update the probabilistic risk assessment (PRA) for the PRISM sodium fast reactor. At a high level, the primary outcome of the project was the development of a next-generation PRA that is intended to enable risk-informed prioritization of safety- and reliability-focused research and development. A central Argonne task during this project was a reliability assessment of passive safety systems, which included the Reactor Vessel Auxiliary Cooling System (RVACS) and the inherent reactivity feedbacks of the metal fuel core. Both systems were examinedmore » utilizing a methodology derived from the Reliability Method for Passive Safety Functions (RMPS), with an emphasis on developing success criteria based on mechanistic system modeling while also maintaining consistency with the Fuel Damage Categories (FDCs) of the mechanistic source term assessment. This paper provides an overview of the reliability analyses of both systems, including highlights of the FMEAs, the construction of best-estimate models, uncertain parameter screening and propagation, and the quantification of system failure probability. In particular, special focus is given to the methodologies to perform the analysis of uncertainty propagation and the determination of the likelihood of violating FDC limits. Additionally, important lessons learned are also reviewed, such as optimal sampling methodologies for the discovery of low likelihood failure events and strategies for the combined treatment of aleatory and epistemic uncertainties.« less

  8. Mental health system governance in Nigeria: challenges, opportunities and strategies for improvement.

    PubMed

    Abdulmalik, J; Kola, L; Gureje, O

    2016-01-01

    A health systems approach to understanding efforts for improving health care services is gaining traction globally. A component of this approach focuses on health system governance (HSG), which can make or mar the successful implementation of health care interventions. Very few studies have explored HSG in low- and middle-income countries, including Nigeria. Studies focusing on mental health system governance, are even more of a rarity. This study evaluates the mental HSG of Nigeria with a view to understanding the challenges, opportunities and strategies for strengthening it. This study was conducted as part of the project, Emerging Mental Health Systems in Low and Middle Income Countries (Emerald). A multi-method study design was utilized to evaluate the mental HSG status of Nigeria. A situational analysis of the health policy and legal environment in the country was performed. Subsequently, 30 key informant interviews were conducted at national, state and district levels to explore the country's mental HSG. The existing policy, legislative and institutional framework for HSG in Nigeria reveals a complete exclusion of mental health in key health sector documents. The revised mental health policy is however promising. Using the Siddiqi framework categories, we identified pragmatic strategies for mental health system strengthening that include a consideration of existing challenges and opportunities within the system. The identified strategies provide a template for the subsequent activities of the Emerald Programme (and other interventions), towards strengthening the mental health system of Nigeria.

  9. Comprehensive Approach to Pupil Planning: Stage III - Instructional Planning (Includes Data Sources Within the CAPP System and Teacher's Instructional Plan). Experimental Edition.

    ERIC Educational Resources Information Center

    Vlasak, Frances Stetson; Kaufman, Martin J.

    Presented is Stage III of the Comprehensive Approach to Pupil Planning (CAPP) System, a three-stage model for planning educational interventions in the regular and special education classrooms and for guiding placement decisions. The guide focuses on the instructional planning team with sections on the following: Stage III personnel; roles and…

  10. First European Congress on Documentation Systems and Networks. Luxembourg, 16th, 17th and 18th May 1973.

    ERIC Educational Resources Information Center

    Commission des Communautes Europeennes (Luxembourg).

    The conference proceedings contained in this document include invited papers, transcripts of discussions following those papers, and the reports of topical committees that met during the three day conference held in Luxembourg, May 1973. The focus of the conference was on the design and use of information retrieval and data base systems in various…

  11. Early Childhood Education Learning System for Three-and Four-Year-Old Migrant Children, McAllen, Texas. Evaluation Report, 1968-1969.

    ERIC Educational Resources Information Center

    Southwest Educational Development Lab., Austin, TX.

    This document reports on a program seen as an integral part of a total educational development plan for migrant children. The Early Childhood Education Learning System is an instructional program which includes staff development and parent-school-community involvement. Focus is on the special learning problems of Mexican-American children and the…

  12. Northwest U.S. agriculture in a changing climate: collaboratively defined research and extension priorities

    Treesearch

    Georgine G. Yorgey; Sonia A. Hall; Elizabeth R. Allen; Elizabeth M. Whitefield; Nichole M. Embertson; Vincent P. Jones; Brooke R. Saari; Kirti Rajagopalan; Gabrielle E. Roesch-McNally; Beatrice Van Horne; John T. Abatzoglou; Harold P. Collins; Laurie L. Houston; Timothy W. Ewing; Chad E. Kruger

    2017-01-01

    In order for agricultural systems to successfully mitigate and adapt to climate change there is a need to coordinate and prioritize next steps for research and extension. This includes focusing on “win-win” management practices that simultaneously provide short-term benefits to farmers and improve the sustainability and resiliency of agricultural systems with respect...

  13. The 1981 Goddard Space Flight Center Battery Workshop

    NASA Technical Reports Server (NTRS)

    Halpert, G. (Editor)

    1982-01-01

    Results of testing, analysis, and development of lithium, nickel-cadmium, and nickel-hydrogen batteries are reported. Focus is on the improvement of power systems in the areas of high capacity, high energy density, and long cycle and storage life. Applications of these batteries as spacecraft power supplies are discussed. Those spacecraft include deepspace probes, spacecraft in geostationary orbit, and large space systems in low-Earth orbit.

  14. The National Manpower Survey of the Criminal Justice System. Volume Five: Criminal Justice Education and Training.

    ERIC Educational Resources Information Center

    National Planning Association, Washington, DC.

    Focusing on education and training needs for law enforcement and criminal justice personnel, this document is one in a series of six volumes reporting the results of the National Manpower Survey (NMS) of the Criminal Justice System. Chapter 1 of ten chapters provides an overview of nine types of educational and/or training programs, including the…

  15. Review of Massachusetts Child Care Subsidy Eligibility Policies and Practices: A Report for the Assessment of the Massachusetts Subsidized Child Care System. Research Report

    ERIC Educational Resources Information Center

    Adams, Gina; Katz, Michael

    2015-01-01

    This report summarizes findings from a review of Massachusetts' child care subsidy eligibility policies and implementation practices. The review included interviews and focus groups with approximately 60 experts and stakeholders with a broad range of perspectives on the system. It identifies several important issues that, if addressed, could…

  16. F-35 Joint Strike Fighter Aircraft (F-35)

    DTIC Science & Technology

    2013-12-01

    Critical Design Review; announcing the decision to terminate development of an alternate Helmet Mounted Display System (HMDS); completing the 2nd F-35B...the 100th aircraft from the production facility at Fort Worth, Texas; and resolving lingering technical design shortfalls to include the F-35C...emphasis on: regular design reviews, systems engineering discipline, software development planning with baseline review boards, and focused metrics

  17. Developing a minimum dataset for nursing team leader handover in the intensive care unit: A focus group study.

    PubMed

    Spooner, Amy J; Aitken, Leanne M; Corley, Amanda; Chaboyer, Wendy

    2018-01-01

    Despite increasing demand for structured processes to guide clinical handover, nursing handover tools are limited in the intensive care unit. The study aim was to identify key items to include in a minimum dataset for intensive care nursing team leader shift-to-shift handover. This focus group study was conducted in a 21-bed medical/surgical intensive care unit in Australia. Senior registered nurses involved in team leader handovers were recruited. Focus groups were conducted using a nominal group technique to generate and prioritise minimum dataset items. Nurses were presented with content from previous team leader handovers and asked to select which content items to include in a minimum dataset. Participant responses were summarised as frequencies and percentages. Seventeen senior nurses participated in three focus groups. Participants agreed that ISBAR (Identify-Situation-Background-Assessment-Recommendations) was a useful tool to guide clinical handover. Items recommended to be included in the minimum dataset (≥65% agreement) included Identify (name, age, days in intensive care), Situation (diagnosis, surgical procedure), Background (significant event(s), management of significant event(s)) and Recommendations (patient plan for next shift, tasks to follow up for next shift). Overall, 30 of the 67 (45%) items in the Assessment category were considered important to include in the minimum dataset and focused on relevant observations and treatment within each body system. Other non-ISBAR items considered important to include related to the ICU (admissions to ICU, staffing/skill mix, theatre cases) and patients (infectious status, site of infection, end of life plan). Items were further categorised into those to include in all handovers and those to discuss only when relevant to the patient. The findings suggest a minimum dataset for intensive care nursing team leader shift-to-shift handover should contain items within ISBAR along with unit and patient specific information to maintain continuity of care and patient safety across shift changes. Copyright © 2017 Australian College of Critical Care Nurses Ltd. All rights reserved.

  18. SU-E-J-03: Characterization of the Precision and Accuracy of a New, Preclinical, MRI-Guided Focused Ultrasound System for Image-Guided Interventions in Small-Bore, High-Field Magnets

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ellens, N; Farahani, K

    2015-06-15

    Purpose: MRI-guided focused ultrasound (MRgFUS) has many potential and realized applications including controlled heating and localized drug delivery. The development of many of these applications requires extensive preclinical work, much of it in small animal models. The goal of this study is to characterize the spatial targeting accuracy and reproducibility of a preclinical high field MRgFUS system for thermal ablation and drug delivery applications. Methods: The RK300 (FUS Instruments, Toronto, Canada) is a motorized, 2-axis FUS positioning system suitable for small bore (72 mm), high-field MRI systems. The accuracy of the system was assessed in three ways. First, the precisionmore » of the system was assessed by sonicating regular grids of 5 mm squares on polystyrene plates and comparing the resulting focal dimples to the intended pattern, thereby assessing the reproducibility and precision of the motion control alone. Second, the targeting accuracy was assessed by imaging a polystyrene plate with randomly drilled holes and replicating the hole pattern by sonicating the observed hole locations on intact polystyrene plates and comparing the results. Third, the practicallyrealizable accuracy and precision were assessed by comparing the locations of transcranial, FUS-induced blood-brain-barrier disruption (BBBD) (observed through Gadolinium enhancement) to the intended targets in a retrospective analysis of animals sonicated for other experiments. Results: The evenly-spaced grids indicated that the precision was 0.11 +/− 0.05 mm. When image-guidance was included by targeting random locations, the accuracy was 0.5 +/− 0.2 mm. The effective accuracy in the four rodent brains assessed was 0.8 +/− 0.6 mm. In all cases, the error appeared normally distributed (p<0.05) in both orthogonal axes, though the left/right error was systematically greater than the superior/inferior error. Conclusions: The targeting accuracy of this device is sub-millimeter, suitable for many preclinical applications including focused drug delivery and thermal therapy. Funding support provided by Philips Healthcare.« less

  19. Robotically assisted MRgFUS system

    NASA Astrophysics Data System (ADS)

    Jenne, Jürgen W.; Krafft, Axel J.; Maier, Florian; Rauschenberg, Jaane; Semmler, Wolfhard; Huber, Peter E.; Bock, Michael

    2010-03-01

    Magnetic resonance imaging guided focus ultrasound surgery (MRgFUS) is a highly precise method to ablate tissue non-invasively. The objective of this ongoing work is to establish an MRgFUS therapy unit consisting of a specially designed FUS applicator as an add-on to a commercial robotic assistance system originally designed for percutaneous needle interventions in whole-body MRI systems. The fully MR compatible robotic assistance system InnoMotion™ (Synthes Inc., West Chester, USA; formerly InnoMedic GmbH, Herxheim, Germany) offers six degrees of freedom. The developed add-on FUS treatment applicator features a fixed focus ultrasound transducer (f = 1.7 MHz; f' = 68 mm, NA = 0.44, elliptical shaped -6-dB-focus: 8.1 mm length; O/ = 1.1 mm) embedded in a water-filled flexible bellow. A Mylar® foil is used as acoustic window encompassed by a dedicated MRI loop coil. For FUS application, the therapy unit is directly connected to the head of the robotic system, and the treatment region is targeted from above. A newly in-house developed software tool allowed for complete remote control of the MRgFUS-robot system and online analysis of MRI thermometry data. The system's ability for therapeutic relevant focal spot scanning was tested in a closed-bore clinical 1.5 T MR scanner (Magnetom Symphony, Siemens AG, Erlangen, Germany) in animal experiments with pigs. The FUS therapy procedure was performed entirely under MRI guidance including initial therapy planning, online MR-thermometry, and final contrast enhanced imaging for lesion detection. In vivo trials proved the MRgFUS-robot system as highly MR compatible. MR-guided focal spot scanning experiments were performed and a well-defined pattern of thermal tissue lesions was created. A total in vivo positioning accuracy of the US focus better than 2 mm was estimated which is comparable to existing MRgFUS systems. The newly developed FUS-robotic system offers an accurate, highly flexible focus positioning. With its access to the patient from above, it provides a wide range of flexibility for acoustic target access. In the next step, motion correction unit should be integrated.

  20. Bioregenerative life support systems for microgravity

    NASA Technical Reports Server (NTRS)

    Nevill, Gail E., Jr.; Hessel, Michael I., Jr.; Rodriguez, Jose; Morgan, Steve (Editor)

    1993-01-01

    NASA's Controlled Ecological Life Support System (CELSS) project centers on growing plants and recycling wastes in space. The current version of the biomass production chamber (BPC) uses a hydroponic system for nutrient delivery. To optimize plant growth and conserve system resources, the content of the nutrient solution which feeds the plants must be constantly monitored. The macro-nutrients (greater than ten ppm) in the solution include nitrogen, phosphorous, potassium, calcium, magnesium, and sulphur; the micro-nutrients (less than ten ppm) include iron, copper, manganese, zinc, and boron. The goal of this project is to construct a computer-controlled system of ion detectors that will accurately measure the concentrations of several necessary ions in solution. The project focuses on the use of a sensor array to eliminate problems of interference and temperature dependence.

  1. Computer Code For Turbocompounded Adiabatic Diesel Engine

    NASA Technical Reports Server (NTRS)

    Assanis, D. N.; Heywood, J. B.

    1988-01-01

    Computer simulation developed to study advantages of increased exhaust enthalpy in adiabatic turbocompounded diesel engine. Subsytems of conceptual engine include compressor, reciprocator, turbocharger turbine, compounded turbine, ducting, and heat exchangers. Focus of simulation of total system is to define transfers of mass and energy, including release and transfer of heat and transfer of work in each subsystem, and relationship among subsystems. Written in FORTRAN IV.

  2. Advanced Metalworking Solutions for Naval Systems That Go In Harm’s Way

    DTIC Science & Technology

    2013-01-01

    quarter century of projects, including early research and development of technologies such as semi-solid metalworking; powder metallurgy; and process...modeling and simulation. More recent projects have focused on friction stir welding, hybrid laser -arc welded metallic sandwich panels, and improved...Metalworking Center has optimized a wide variety of manufacturing technologies throughout its 25-year history, including powder metallurgy processing, semi

  3. The CRISPR-Cas system in Enterobacteriaceae.

    PubMed

    Medina-Aparicio, Liliana; Dávila, Sonia; Rebollar-Flores, Javier E; Calva, Edmundo; Hernández-Lucas, Ismael

    2018-02-01

    In nature, microorganisms are constantly exposed to multiple viral infections and thus have developed many strategies to survive phage attack and invasion by foreign DNA. One of such strategies is the clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated proteins (Cas) bacterial immunological system. This defense mechanism is widespread in prokaryotes including several families such as Enterobacteriaceae. Much knowledge about the CRISPR-Cas system has been generated, including its biological functions, transcriptional regulation, distribution, utility as a molecular marker and as a tool for specific genome editing. This review focuses on these aspects and describes the state of the art of the CRISPR-Cas system in the Enterobacteriaceae bacterial family. © FEMS 2018. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  4. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zitney, S.E.

    This presentation will examine process systems engineering R&D needs for application to advanced fossil energy (FE) systems and highlight ongoing research activities at the National Energy Technology Laboratory (NETL) under the auspices of a recently launched Collaboratory for Process & Dynamic Systems Research. The three current technology focus areas include: 1) High-fidelity systems with NETL's award-winning Advanced Process Engineering Co-Simulator (APECS) technology for integrating process simulation with computational fluid dynamics (CFD) and virtual engineering concepts, 2) Dynamic systems with R&D on plant-wide IGCC dynamic simulation, control, and real-time training applications, and 3) Systems optimization including large-scale process optimization, stochastic simulationmore » for risk/uncertainty analysis, and cost estimation. Continued R&D aimed at these and other key process systems engineering models, methods, and tools will accelerate the development of advanced gasification-based FE systems and produce increasingly valuable outcomes for DOE and the Nation.« less

  5. Pediatric primary care as a component of systems of care.

    PubMed

    Brown, Jonathan D

    2010-02-01

    Systems of care should be defined in a manner that includes primary care. The current definition of systems of care shares several attributes with the definition of primary care: both are defined as community-based services that are accessible, accountable, comprehensive, coordinated, culturally competent, and family focused. However, systems of care is defined as serving only children and youth with serious emotional disturbance and their families and does not fully embrace the concept of primary prevention. Although similarities in the definitions of primary care and systems of care may provide a theoretical foundation for including primary care within the systems of care framework, a definition of systems of care that incorporates the idea of prevention and takes into account the broad population served in primary care would provide communities with a definition that can be used to further the work of integrating primary care into systems of care.

  6. High-intensity focused ultrasound (HIFU) array system for image-guided ablative therapy (IGAT)

    NASA Astrophysics Data System (ADS)

    Kaczkowski, Peter J.; Keilman, George W.; Cunitz, Bryan W.; Martin, Roy W.; Vaezy, Shahram; Crum, Lawrence A.

    2003-06-01

    Recent interest in using High Intensity Focused Ultrasound (HIFU) for surgical applications such as hemostasis and tissue necrosis has stimulated the development of image-guided systems for non-invasive HIFU therapy. Seeking an all-ultrasound therapeutic modality, we have developed a clinical HIFU system comprising an integrated applicator that permits precisely registered HIFU therapy delivery and high quality ultrasound imaging using two separate arrays, a multi-channel signal generator and RF amplifier system, and a software program that provides the clinician with a graphical overlay of the ultrasound image and therapeutic protocol controls. Electronic phasing of a 32 element 2 MHz HIFU annular array allows adjusting the focus within the range of about 4 to 12 cm from the face. A central opening in the HIFU transducer permits mounting a commercial medical imaging scanhead (ATL P7-4) that is held in place within a special housing. This mechanical fixture ensures precise coaxial registration between the HIFU transducer and the image plane of the imaging probe. Recent enhancements include development of an acoustic lens using numerical simulations for use with a 5-element array. Our image-guided therapy system is very flexible and enables exploration of a variety of new HIFU therapy delivery and monitoring approaches in the search for safe, effective, and efficient treatment protocols.

  7. Stitching interferometry for ellipsoidal x-ray mirrors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yumoto, Hirokatsu, E-mail: yumoto@spring8.or.jp; Koyama, Takahisa; Matsuyama, Satoshi

    2016-05-15

    Ellipsoidal mirrors, which can efficiently produce a two-dimensional focusing beam with a single mirror, are superior x-ray focusing optics, especially when compared to elliptical-cylinder mirrors in the Kirkpatrick–Baez geometry. However, nano-focusing ellipsoidal mirrors are not commonly used for x-ray optics because achieving the accuracy required for the surface metrology of nano-focusing ellipsoidal mirrors is difficult due to their small radius of curvature along the short ellipsoidal axis. Here, we developed a surface metrology system for nano-focusing ellipsoidal mirrors using stitching interferometric techniques. The developed system simultaneously measures sub-aperture shapes with a microscopic interferometer and the tilt angles of the sub-aperturemore » shapes with a large Fizeau interferometer. After correcting the systematic errors included in the sub-aperture shapes, the entire mirror shape is calculated by stitching the sub-aperture shapes based on the obtained relative angles between partially overlapped sub-apertures. In this study, we developed correction methods for systematic errors in sub-aperture shapes that originated from off-axis aberrations produced in the optics of the microscopic interferometer. The systematic errors on an ellipsoidal mirror were estimated by measuring a series of tilted plane substrates and the ellipsoidal substrate. From measurements of an ellipsoidal mirror with a 3.6-mm radius of curvature at the mirror center, we obtained a measurement repeatability of 0.51 nm (root-mean-square) in an assessment area of 0.5 mm × 99.18 mm. This value satisfies the requirements for surface metrology of nano-focusing x-ray mirrors. Thus, the developed metrology system should be applicable for fabricating nano-focusing ellipsoidal mirrors.« less

  8. The SMART-NAS Testbed

    NASA Technical Reports Server (NTRS)

    Aquilina, Rudolph A.

    2015-01-01

    The SMART-NAS Testbed for Safe Trajectory Based Operations Project will deliver an evaluation capability, critical to the ATM community, allowing full NextGen and beyond-NextGen concepts to be assessed and developed. To meet this objective a strong focus will be placed on concept integration and validation to enable a gate-to-gate trajectory-based system capability that satisfies a full vision for NextGen. The SMART-NAS for Safe TBO Project consists of six sub-projects. Three of the sub-projects are focused on exploring and developing technologies, concepts and models for evolving and transforming air traffic management operations in the ATM+2 time horizon, while the remaining three sub-projects are focused on developing the tools and capabilities needed for testing these advanced concepts. Function Allocation, Networked Air Traffic Management and Trajectory Based Operations are developing concepts and models. SMART-NAS Test-bed, System Assurance Technologies and Real-time Safety Modeling are developing the tools and capabilities to test these concepts. Simulation and modeling capabilities will include the ability to assess multiple operational scenarios of the national airspace system, accept data feeds, allowing shadowing of actual operations in either real-time, fast-time and/or hybrid modes of operations in distributed environments, and enable integrated examinations of concepts, algorithms, technologies, and NAS architectures. An important focus within this project is to enable the development of a real-time, system-wide safety assurance system. The basis of such a system is a continuum of information acquisition, analysis, and assessment that enables awareness and corrective action to detect and mitigate potential threats to continuous system-wide safety at all levels. This process, which currently can only be done post operations, will be driven towards "real-time" assessments in the 2035 time frame.

  9. A starting point for delivery reform. Catholic healthcare providers can receive guidance from "A Time to Be Old, a Time to Flourish".

    PubMed

    1992-03-01

    The ideal healthcare delivery system is client focused and ensures that the individual and the family receive the appropriate mix of services to meet their needs. Healthcare delivery should be presented as a coordinated continuum of care. Key integrating elements are essential to provide healthcare services on a day-by-day basis as a continuum of care. Integrating elements that form the bridge between clients and services include planning, care management, a management information system, financing, and an appropriate administrative structure. Many Catholic healthcare providers are expanding by acquiring a variety of services. However, many of these acquisitions are in response to today's competitive environment, whereas a true continuum of care must focus on the client's range of functional needs. Catholic providers must keep in mind that not all services they provide will be profitable. Although Catholic healthcare providers will be pressured to focus on fiscal strength and market position, they must put the client's holistic needs first. By doing so, they can help create a client-centered healthcare system in their communities.

  10. Pipe degradation investigations for optimization of flow-accelerated corrosion inspection location selection

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chandra, S.; Habicht, P.; Chexal, B.

    1995-12-01

    A large amount of piping in a typical nuclear power plant is susceptible to Flow-Accelerated Corrosion (FAC) wall thinning to varying degrees. A typical PAC monitoring program includes the wall thickness measurement of a select number of components in order to judge the structural integrity of entire systems. In order to appropriately allocate resources and maintain an adequate FAC program, it is necessary to optimize the selection of components for inspection by focusing on those components which provide the best indication of system susceptibility to FAC. A better understanding of system FAC predictability and the types of FAC damage encounteredmore » can provide some of the insight needed to better focus and optimize the inspection plan for an upcoming refueling outage. Laboratory examination of FAC damaged components removed from service at Northeast Utilities` (NU) nuclear power plants provides a better understanding of the damage mechanisms involved and contributing causes. Selected results of this ongoing study are presented with specific conclusions which will help NU to better focus inspections and thus optimize the ongoing FAC inspection program.« less

  11. The Narrative Arc of TATs: Introduction to the JPA Special Section on Thematic Apperceptive Techniques.

    PubMed

    Jenkins, Sharon Rae

    2017-01-01

    The past decade has seen important developments in thematic apperceptive techniques (TATs), with the creation of new card sets having alternate pictures representing different cultures, new scoring systems becoming available, and increasing international communication of these achievements. However, continuing impediments to the development of a validational literature include lingering mistaken assumptions about the nature of story data, ongoing debates about appropriate psychometric evaluation, and continuing questions about how stimuli and scoring systems should be conceptualized and interpreted. Negotiating the publication system can impede some potential authors. Excellent work on TATs with children is not well known in the adult-focused journals. The labor burden of meeting increasingly sophisticated publication standards might be a barrier to assessors focused on clinical practice. Accumulating a focused evidence base is challenging given the diversity of criterion variables for which TATs have been used. Research on TATs by clinicians can span the science-practice gap, but the narrative arc can be a dramatic one. The articles in this special section on TATs represent important conceptual, methodological, and substantive innovations.

  12. SWCX Emission from the Helium Focusing Cone - Preliminary Results

    NASA Technical Reports Server (NTRS)

    Snowden, S. L.; Kuntz, K. D.; Collier, M. R.

    2008-01-01

    Preliminary results from an XMM-Newton campaign to study solar wind charge exchange (SWCX) emission from the heliospheric focusing cone of interstellar helium are presented. The detections of enhanced O VII and O VIII emission from the cone are at the 2(sigma) and 4(sigma) levels. The solar wind charge exchange (SWCX) emission in the heliosphere not associated with distinct objects (e.g., comets and planets including exospheric material in and near Earth s magnetosheath) is proportional to the flux of the solar wind and the space density of neutral material. The neutral material originates in the interstellar medium (ISM) and passes through the solar system due to the relative motion of the Sun and the ISM. The flow of the neutral material through the solar system is strongly perturbed by the Sun both by gravity and by radiation pressure. Because of the relative radiative scattering cross sections and the effect of solar gravitation the density of interstellar hydrogen near the Sun is reduced while interstellar helium is gravitationally focused. This creates a helium focusing cone downstream of the Sun [e.g., 1, and references therein].

  13. Consumers, gag rules, and health plans: strategies for a patient-focused market.

    PubMed

    Etheredge, L; Jones, S B

    1997-05-01

    The "gag rule" controversy has become a symbol of new tensions and changing relationships among patients, physicians, and health plans. This paper offers a consumer-focused analysis of these fundamental issues from the point of view of a patient with a chronic illness. It starts with a case study of a specific individual and then considers the systemic incentives and other factors that lead to conflicts among patients, physicians, and health plans. This consumer focus invites the reader to consider managed care with the following question in mind: "What would you want for yourself it you were the patient?" The paper suggests that many private-sector initiatives, as well as government actions, could contribute to a better health care market. Among the reform strategies discussed are (a) professional responsibility and private-sector standards, (b) consumer assistance, and (c) government regulation. All of us, including persons with chronic illness, need a consumer-focused health system. So, too, do physicians and health plans that want to provide excellent care for all of their patients.

  14. Acoustic monitoring method and system in laser-induced optical breakdown (LIOB)

    DOEpatents

    O'Donnell, Matthew [Ann Arbor, MI; Ye, Jing Yong [Ann Arbor, MI; Norris, Theodore B [Dexter, MI; Baker, Jr., James R.; Balogh, Lajos P [Ann Arbor, MI; Milas, Susanne M [Ann Arbor, MI; Emelianov, Stanislav Y [Ann Arbor, MI; Hollman, Kyle W [Fenton, MI

    2008-05-06

    An acoustic monitoring method and system in laser-induced optical breakdown (LIOB) provides information which characterize material which is broken down, microbubbles in the material, and/or the microenvironment of the microbubbles. In one embodiment of the invention, femtosecond laser pulses are focused just inside the surface of a volume of aqueous solution which may include dendrimer nanocomposite (DNC) particles. A tightly focused, high frequency, single-element ultrasonic transducer is positioned such that its focus coincides axially and laterally with this laser focus. When optical breakdown occurs, a microbubble forms and a shock or pressure wave is emitted (i.e., acoustic emission). In addition to this acoustic signal, the microbubble may be actively probed with pulse-echo measurements from the same transducer. After the microbubble forms, received pulse-echo signals have an extra pulse, describing the microbubble location and providing a measure of axial microbubble size. Wavefield plots of successive recordings illustrate the generation, growth, and collapse of microbubbles due to optical breakdown. These same plots can also be used to quantify LIOB thresholds.

  15. Optical system

    NASA Technical Reports Server (NTRS)

    Breckinridge, J. B.; Page, N. A.; Shack, R. V.; Shannon, R. R. (Inventor)

    1985-01-01

    Disclosed is an otpical system used in a spacecraft to observe a remote surface and provide a spatial and spectral image of this surface. The optical system includes aspheric and spherical mirrors aligned to focus at a first focal plane an image of the surface, and a mirror at this first focal plane which reflects light back on to the spherical mirror. This spherical mirror collimates the light and directs it through a prism which disperses it. The dispersed light is then focused on an array of light responsive elements disposed at a second focal plane. The prism is designed such that it disperses light into components of different wavelengths, with the components of shorter wavelengths being dispersed more than the components of longer wavelengths to present at the second focal plane a distribution pattern in which preselected groupings of the components are dispersed over essentially equal spacing intervals.

  16. In situ product removal in fermentation systems: improved process performance and rational extractant selection.

    PubMed

    Dafoe, Julian T; Daugulis, Andrew J

    2014-03-01

    The separation of inhibitory compounds as they are produced in biotransformation and fermentation systems is termed in situ product removal (ISPR). This review examines recent ISPR strategies employing several classes of extractants including liquids, solids, gases, and combined extraction systems. Improvement through the simple application of an auxiliary phase are tabulated and summarized to indicate the breadth of recent ISPR activities. Studies within the past 5 years that have highlighted and have discussed "second phase" properties, and that have an effect on fermentation performance, are particular focus of this review. ISPR, as a demonstrably effective processing strategy, continues to be widely adopted as more applications are explored; however, focus on the properties of extractants and their rational selection based on first principle considerations will likely be key to successfully applying ISPR to more challenging target molecules.

  17. Ethanol distribution, dispensing, and use: analysis of a portion of the biomass-to-biofuels supply chain using system dynamics.

    PubMed

    Vimmerstedt, Laura J; Bush, Brian; Peterson, Steve

    2012-01-01

    The Energy Independence and Security Act of 2007 targets use of 36 billion gallons of biofuels per year by 2022. Achieving this may require substantial changes to current transportation fuel systems for distribution, dispensing, and use in vehicles. The U.S. Department of Energy and the National Renewable Energy Laboratory designed a system dynamics approach to help focus government action by determining what supply chain changes would have the greatest potential to accelerate biofuels deployment. The National Renewable Energy Laboratory developed the Biomass Scenario Model, a system dynamics model which represents the primary system effects and dependencies in the biomass-to-biofuels supply chain. The model provides a framework for developing scenarios and conducting biofuels policy analysis. This paper focuses on the downstream portion of the supply chain-represented in the distribution logistics, dispensing station, and fuel utilization, and vehicle modules of the Biomass Scenario Model. This model initially focused on ethanol, but has since been expanded to include other biofuels. Some portions of this system are represented dynamically with major interactions and feedbacks, especially those related to a dispensing station owner's decision whether to offer ethanol fuel and a consumer's choice whether to purchase that fuel. Other portions of the system are modeled with little or no dynamics; the vehicle choices of consumers are represented as discrete scenarios. This paper explores conditions needed to sustain an ethanol fuel market and identifies implications of these findings for program and policy goals. A large, economically sustainable ethanol fuel market (or other biofuel market) requires low end-user fuel price relative to gasoline and sufficient producer payment, which are difficult to achieve simultaneously. Other requirements (different for ethanol vs. other biofuel markets) include the need for infrastructure for distribution and dispensing and widespread use of high ethanol blends in flexible-fuel vehicles.

  18. Ethanol Distribution, Dispensing, and Use: Analysis of a Portion of the Biomass-to-Biofuels Supply Chain Using System Dynamics

    PubMed Central

    Vimmerstedt, Laura J.; Bush, Brian; Peterson, Steve

    2012-01-01

    The Energy Independence and Security Act of 2007 targets use of 36 billion gallons of biofuels per year by 2022. Achieving this may require substantial changes to current transportation fuel systems for distribution, dispensing, and use in vehicles. The U.S. Department of Energy and the National Renewable Energy Laboratory designed a system dynamics approach to help focus government action by determining what supply chain changes would have the greatest potential to accelerate biofuels deployment. The National Renewable Energy Laboratory developed the Biomass Scenario Model, a system dynamics model which represents the primary system effects and dependencies in the biomass-to-biofuels supply chain. The model provides a framework for developing scenarios and conducting biofuels policy analysis. This paper focuses on the downstream portion of the supply chain–represented in the distribution logistics, dispensing station, and fuel utilization, and vehicle modules of the Biomass Scenario Model. This model initially focused on ethanol, but has since been expanded to include other biofuels. Some portions of this system are represented dynamically with major interactions and feedbacks, especially those related to a dispensing station owner’s decision whether to offer ethanol fuel and a consumer’s choice whether to purchase that fuel. Other portions of the system are modeled with little or no dynamics; the vehicle choices of consumers are represented as discrete scenarios. This paper explores conditions needed to sustain an ethanol fuel market and identifies implications of these findings for program and policy goals. A large, economically sustainable ethanol fuel market (or other biofuel market) requires low end-user fuel price relative to gasoline and sufficient producer payment, which are difficult to achieve simultaneously. Other requirements (different for ethanol vs. other biofuel markets) include the need for infrastructure for distribution and dispensing and widespread use of high ethanol blends in flexible-fuel vehicles. PMID:22606230

  19. Modelling results for the thermal management sub-system of a combined heat and power (CHP) fuel cell system (FCS)

    NASA Astrophysics Data System (ADS)

    Colella, Whitney G.

    Although the fuel cells research and development community has traditionally focused the majority of its efforts on improving the fuel cell stack's voltage (electrical efficiency), combined heat and power (CHP) fuel cell system (FCSs) may achieve a competitive advantage over conventional generators only if the research and development community refocuses its efforts on cultivating other inherent technical qualities of such systems. Based on an analysis of their use within energy markets, these inherent qualities include (1) an ability to vary their electrical load rapidly, (2) an ability to vary their heat to power ratio during operation, and (3) an ability to deliver their waste heat to a useful thermal sink. This article focuses on the last of three design objectives: effectively capturing heat from a CHP FCS. This article (1) delineates the design specifications for a 6 kWe CHP FCS, (2) analyses four possible cooling loop configurations for this system, and (3) concludes which one of these provides the optimal heat recovery performance.

  20. High Intensity Focused Ultrasound Tumor Therapy System and Its Application

    NASA Astrophysics Data System (ADS)

    Sun, Fucheng; He, Ye; Li, Rui

    2007-05-01

    At the end of last century, a High Intensity Focused Ultrasound (HIFU) tumor therapy system was successfully developed and manufactured in China, which has been already applied to clinical therapy. This article aims to discuss the HIFU therapy system and its application. Detailed research includes the following: power amplifiers for high-power ultrasound, ultrasound transducers with large apertures, accurate 3-D mechanical drives, a software control system (both high-voltage control and low-voltage control), and the B-mode ultrasonic diagnostic equipment used for treatment monitoring. Research on the dosage of ultrasound required for tumour therapy in multiple human cases has made it possible to relate a dosage formula, presented in this paper, to other significant parameters such as the volume of thermal tumor solidification, the acoustic intensity (I), and the ultrasound emission time (tn). Moreover, the HIFU therapy system can be applied to the clinical treatment of both benign and malignant tumors in the pelvic and abdominal cavity, such as uterine fibroids, liver cancer and pancreatic carcinoma.

  1. Final Report: Subcontract B623868 Algebraic Multigrid solvers for coupled PDE systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brannick, J.

    The Pennsylvania State University (“Subcontractor”) continued to work on the design of algebraic multigrid solvers for coupled systems of partial differential equations (PDEs) arising in numerical modeling of various applications, with a main focus on solving the Dirac equation arising in Quantum Chromodynamics (QCD). The goal of the proposed work was to develop combined geometric and algebraic multilevel solvers that are robust and lend themselves to efficient implementation on massively parallel heterogeneous computers for these QCD systems. The research in these areas built on previous works, focusing on the following three topics: (1) the development of parallel full-multigrid (PFMG) andmore » non-Galerkin coarsening techniques in this frame work for solving the Wilson Dirac system; (2) the use of these same Wilson MG solvers for preconditioning the Overlap and Domain Wall formulations of the Dirac equation; and (3) the design and analysis of algebraic coarsening algorithms for coupled PDE systems including Stokes equation, Maxwell equation and linear elasticity.« less

  2. Space-based solar power conversion and delivery systems study. Volume 1: Executive summary

    NASA Technical Reports Server (NTRS)

    Hazelrigg, G. A., Jr.

    1976-01-01

    The technical and economic aspects of satellite solar power systems are presented with a focus on the current configuration 5000 MW system. The technical studies include analyses of the orbital system structures, control and stationkeeping, and the formulation of program plans and costs for input to the economic analyses. The economic analyses centered about the development and use of a risk analysis model for a system cost assessment, identification of critical issues and technologies, and to provide information for programmatic decision making. A preliminary economic examination of some utility interface issues is included. Under the present state-of-knowledge, it is possible to formulate a program plan for the development of a satellite solar power system that can be economically justified. The key area of technological uncertainty is man's ability to fabricate and assemble large structures in space.

  3. Facility Overview and Double-Focusing Thermal Triple-Axis Spectrometer at the NCNR

    NASA Astrophysics Data System (ADS)

    Lynn, Jeffrey

    2012-02-01

    We will briefly overview the neutron scattering instrumentation at the NCNR, but will focus the talk on the capabilities of the new thermal triple-axis spectrometer is located at the BT-7 beam port [1]. This spectrometer takes full advantage of the large 165 mm diameter reactor beam to tailor the dual 20x20 cm^2 double-focusing monochromator system to provide monochromatic fluxes exceeding 10^8 n/cm^2/s onto the sample. The two monochromators installed are PG(002) and Cu(220), which provide incident energies for 5 meV to above 500 meV. The computer controlled analyzer system offers six standard modes of operation, including a diffraction detector, a position-sensitive detector (PSD) in diffraction mode, horizontal energy focusing analyzer with detector, a Q-E mode employing a flat analyzer and PSD, a constant-E mode with the analyzer crystal system and PSD, and a conventional mode with a selection of S"oller collimators and detector. Additional configurations for specific measurement needs are also available. The capabilities and performance will be discussed and examples of published data presented. [4pt] [1] J. W. Lynn, Y. Chen, S. Chang, Y. Zhao, S. Chi, W. Ratcliff, II, B. G. Ueland, and R. W. Erwin, J. Research NIST 117 (in press).

  4. CSBF Engineering Overview

    NASA Astrophysics Data System (ADS)

    Orr, Dwayne

    The Columbia Scientific Balloon Facility (CSBF) at Palestine, Texas provides operational and engineering support for the launch of NASA Scientific Balloons. Over the years with the support of the NASA Balloon Program Office, CSBF has developed unique flight systems with the focus of providing a highly reliable, cost effective medium for giving Scientist's access to a near space environment. This paper will provide an overview of the CSBF flight systems with an emphasis on recent developments and plans for the future including: RIP Stitch -Parachute Shock Attenuation system, MIP -Micro Instrumentation Package, GAPR -Gondola Automatic Parachute Release system, NASA TDRSS High Gain Antenna system, Superpressure flight video systems

  5. Advanced Space Transportation Program (ASTP)

    NASA Image and Video Library

    2002-10-01

    NASA's Marshall Space Flight Center in Huntsville, Alabama, manages the Space Launch Initiative (SLI), NASA's priority developmental program focused on empowering America's leadership in space. SLI includes commercial, higher education, and defense partnerships and contracts to offer widespread participation in both the risk and success of developing our nation's next-generation reusable launch vehicle. This photo depicts an artist's concept of a future second-generation launch vehicle. For the SLI, architecture definition includes all components of the next-generation reusable launch system: Earth-to-orbit vehicles (the Space Shuttle is the first generation earth-to-orbit vehicle), crew transfer vehicles, transfer stages, ground processing systems, flight operations systems, and development of business case strategies. Three contractor teams have each been funded to develop potential second- generation reusable launch system architectures: The Boeing Company of Seal Beach, California; Lockheed Martin Corporation of Denver, Colorado along with a team including Northrop Grumman of El Segundo, California; and Orbital Sciences Corporation of Dulles, Virginia.

  6. Advanced Space Transportation Program (ASTP)

    NASA Image and Video Library

    2002-10-01

    NASA's Marshall Space Flight Center in Huntsville, Alabama, manages the Space Launch Initiative (SLI), NASA's priority developmental program focused on empowering America's leadership in space. SLI includes commercial, higher education and defense partnerships and contracts to offer widespread participation in both the risk and success of developing our nation's next-generation reusable launch vehicle. This photo depicts an artist's concept of a future second-generation launch vehicle during separation of stages. For SLI, architecture definition includes all components of the next-generation reusable launch system: Earth-to-orbit vehicles (the Space Shuttle is the first-generation earth-to-orbit vehicle), crew transfer vehicles, transfer stages, ground processing systems, flight operations systems, and development of business case strategies. Three contractor teams have each been funded to develop potential second generation reusable launch system architectures: The Boeing Company of Seal Beach, California; Lockheed Martin Corporation of Denver, Colorado; a team including Northrop Grumman of El Segundo, California; and Orbital Sciences Corporation of Dulles, Virginia.

  7. SLI Artist's Concept

    NASA Technical Reports Server (NTRS)

    2002-01-01

    NASA's Marshall Space Flight Center in Huntsville, Alabama, manages the Space Launch Initiative (SLI), NASA's priority developmental program focused on empowering America's leadership in space. SLI includes commercial, higher education, and defense partnerships and contracts to offer widespread participation in both the risk and success of developing our nation's next-generation reusable launch vehicle. This photo depicts an artist's concept of a future second-generation launch vehicle. For the SLI, architecture definition includes all components of the next-generation reusable launch system: Earth-to-orbit vehicles (the Space Shuttle is the first generation earth-to-orbit vehicle), crew transfer vehicles, transfer stages, ground processing systems, flight operations systems, and development of business case strategies. Three contractor teams have each been funded to develop potential second- generation reusable launch system architectures: The Boeing Company of Seal Beach, California; Lockheed Martin Corporation of Denver, Colorado along with a team including Northrop Grumman of El Segundo, California; and Orbital Sciences Corporation of Dulles, Virginia.

  8. SLI Artist `s Launch Concept

    NASA Technical Reports Server (NTRS)

    2002-01-01

    NASA's Marshall Space Flight Center in Huntsville, Alabama, manages the Space Launch Initiative (SLI), NASA's priority developmental program focused on empowering America's leadership in space. SLI includes commercial, higher education and defense partnerships and contracts to offer widespread participation in both the risk and success of developing our nation's next-generation reusable launch vehicle. This photo depicts an artist's concept of a future second-generation launch vehicle during launch. For SLI, architecture definition includes all components of the next-generation reusable launch system: Earth-to-orbit vehicles (the Space Shuttle is the first generation earth-to-orbit vehicle), crew transfer vehicles, transfer stages, ground processing systems, flight operations systems, and development of business case strategies. Three contractor teams have each been funded to develop potential second generation reusable launch system architectures: The Boeing Company of Seal Beach, California; Lockheed Martin Corporation of Denver, Colorado along with a team including Northrop Grumman of El Segundo, California; and Orbital Sciences Corporation of Dulles, Virginia.

  9. SLI Artist's Concept-Stage Separation

    NASA Technical Reports Server (NTRS)

    2002-01-01

    NASA's Marshall Space Flight Center in Huntsville, Alabama, manages the Space Launch Initiative (SLI), NASA's priority developmental program focused on empowering America's leadership in space. SLI includes commercial, higher education and defense partnerships and contracts to offer widespread participation in both the risk and success of developing our nation's next-generation reusable launch vehicle. This photo depicts an artist's concept of a future second-generation launch vehicle during separation of stages. For SLI, architecture definition includes all components of the next-generation reusable launch system: Earth-to-orbit vehicles (the Space Shuttle is the first-generation earth-to-orbit vehicle), crew transfer vehicles, transfer stages, ground processing systems, flight operations systems, and development of business case strategies. Three contractor teams have each been funded to develop potential second generation reusable launch system architectures: The Boeing Company of Seal Beach, California; Lockheed Martin Corporation of Denver, Colorado; a team including Northrop Grumman of El Segundo, California; and Orbital Sciences Corporation of Dulles, Virginia.

  10. From Airy to Abbe: quantifying the effects of wide-angle focusing for scalar spherical waves

    NASA Astrophysics Data System (ADS)

    Calm, Yitzi M.; Merlo, Juan M.; Burns, Michael J.; Naughton, Michael J.

    2017-10-01

    Recent advances in optical microscopy have enabled imaging with spatial resolution beyond the diffraction limit. This limit is sometimes taken as one of several different criteria according to different conventions, including Rayleigh’s 0.61λ /NA, Abbe’s 0.5λ /NA, and Sparrow’s 0.47λ /NA. In this paper, we perform a parametric study, numerically integrating the scalar Kirchhoff diffraction integrals, and we propose new functional forms for the resolution limits derived from scalar focusing. The new expressions remain accurate under wide angle focusing, up to 90^\\circ . Our results could materially impact the design of high intensity focused ultrasound systems, and can be used as a qualitative guideline for the design of a particular type of planar optical element: the flat lens metasurface.

  11. Human performance modeling for system of systems analytics :soldier fatigue.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lawton, Craig R.; Campbell, James E.; Miller, Dwight Peter

    2005-10-01

    The military has identified Human Performance Modeling (HPM) as a significant requirement and challenge of future systems modeling and analysis initiatives as can be seen in the Department of Defense's (DoD) Defense Modeling and Simulation Office's (DMSO) Master Plan (DoD 5000.59-P 1995). To this goal, the military is currently spending millions of dollars on programs devoted to HPM in various military contexts. Examples include the Human Performance Modeling Integration (HPMI) program within the Air Force Research Laboratory, which focuses on integrating HPMs with constructive models of systems (e.g. cockpit simulations) and the Navy's Human Performance Center (HPC) established in Septembermore » 2003. Nearly all of these initiatives focus on the interface between humans and a single system. This is insufficient in the era of highly complex network centric SoS. This report presents research and development in the area of HPM in a system-of-systems (SoS). Specifically, this report addresses modeling soldier fatigue and the potential impacts soldier fatigue can have on SoS performance.« less

  12. Pre-Algebra Groups. Concepts & Applications.

    ERIC Educational Resources Information Center

    Montgomery County Public Schools, Rockville, MD.

    Discussion material and exercises related to pre-algebra groups are provided in this five chapter manual. Chapter 1 (mappings) focuses on restricted domains, order of operations (parentheses and exponents), rules of assignment, and computer extensions. Chapter 2 considers finite number systems, including binary operations, clock arithmetic,…

  13. Using Special Libraries to Interface with Developing Country Clientele.

    ERIC Educational Resources Information Center

    Schenck-Hamlin, Donna; George, Paulette Foss

    1986-01-01

    Describes two special collections focusing on postharvest systems of handling, transportation, storage, and marketing of food and feed grain. Highlights include information needs of developing countries (e.g., Egypt, Honduras, Pakistan), and information center activities (communication and marketing, collection building, interpreting client needs,…

  14. Spaceship Earth Revisited.

    ERIC Educational Resources Information Center

    Pultorak, Robert W.

    1981-01-01

    Describes a self-paced undergraduate environmental science course focusing on a theme that earth is similar to a spaceship inasmuch as: (1) both possess finite room and resources, and (2) living things are dependent upon life-support systems for continued survival. Includes a list of laboratory and learning activities. (DS)

  15. School Library Media Centers in a Statewide Network.

    ERIC Educational Resources Information Center

    Fox, Carol

    1990-01-01

    Description of library services in Illinois focuses on school libraries and youth services. Topics discussed include multitype library systems; automation; youth services consultants; data collection for youth services; resource sharing for schools; promotion of reading and library programs; communications networks; and standards and certification…

  16. Investigating the Rights of Youths. Students in Action.

    ERIC Educational Resources Information Center

    Insights on Law & Society, 2002

    2002-01-01

    Focuses on the rights of youth in three articles: (1) "Equal Justice? Girls in the Juvenile Justice System"; (2) "Child Labor: An International Challenge"; and (3) "Should Minors Have Access to Violent Video Games?" Includes learning activities at the end of each article. (CMK)

  17. Neil Snyder | NREL

    Science.gov Websites

    Photo of Neil Snyder Neil Snyder Manager III-Program Management Research Neil.Snyder@nrel.gov management. He has chiefly focused on developing complex systems and his specific expertise is leadership. As has acquired familiarity level expertise in many technical fields including environmental management

  18. Schools under Scrutiny.

    ERIC Educational Resources Information Center

    Organisation for Economic Cooperation and Development, Paris (France).

    The performance of national education systems is a growing concern in many Organisation for Economic Cooperation and Development (OECD) countries. This book focuses on the assessment of school performance in seven countries: England, France, Germany, New Zealand, Spain, Sweden, and the United States. The research questions include: Why are schools…

  19. Genre and Literacy-Modeling Context in Educational Linguistics.

    ERIC Educational Resources Information Center

    Martin, James R.

    1992-01-01

    Complements review in previous volume concerning Australian literacy (in first- and second-language) initiatives that drew on systemic functional linguistics, highlights ongoing research within the same theoretical framework, and focuses on the question of modeling context in educational linguistics. The discussion includes modeling context as…

  20. Youth Victimization: School Climate or Deviant Lifestyles?

    ERIC Educational Resources Information Center

    Zaykowski, Heather; Gunter, Whitney

    2012-01-01

    Despite much focus on school violence, there has been little research that explores the relationship between offending and victimization in various school climates. School climate theory suggests that the school's social system, culture, milieu, and ecological structure affect student outcomes including academic performance, delinquency, and more…

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