5 CFR 293.508 - Type of folder to be used.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Type of folder to be used. 293.508 Section 293.508 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL RECORDS Employee Medical File System Records § 293.508 Type of folder to be used. Each agency must...

[Nationwide Evaluation of the "Parental Folder" and its Utility Value--Insights into the Health and Information Behaviour of Parents].

PubMed

Pawils, S; Busche, W; Schwinn, A; Fillinger, U; Koch, U

2015-09-01

The "parental folder" is meant as a primary prevention programme for children starting at birth with the aim to give access to relevant health knowledge to all parents and to strengthen the parental competence in doctor-parent communication. In a sample of N=1,634 families the effects of the folder were examined in a randomized controlled study in the federal states Rhineland-Palatinate and Saxony. In addition N=103 experts were asked for their valuation of the folder. © Georg Thieme Verlag KG Stuttgart · New York.

Defense Responses in Rice Induced by Silicon Amendment against Infestation by the Leaf Folder Cnaphalocrocis medinalis

PubMed Central

Han, Yongqiang; Li, Pei; Gong, Shaolong; Yang, Lang; Wen, Lizhang; Hou, Maolin

2016-01-01

Silicon (Si) amendment to plants can confer enhanced resistance to herbivores. In the present study, the physiological and cytological mechanisms underlying the enhanced resistance of plants with Si addition were investigated for one of the most destructive rice pests in Asian countries, the rice leaf folder, Cnaphalocrocis medinalis (Guenée). Activities of defense-related enzymes, superoxide dismutase, peroxidase, catalase, phenylalanine ammonia-lyase, and polyphenol oxidase, and concentrations of malondialdehyde and soluble protein in leaves were measured in rice plants with or without leaf folder infestation and with or without Si amendment at 0.32 g Si/kg soil. Silicon amendment significantly reduced leaf folder larval survival. Silicon addition alone did not change activities of defense-related enzymes and malondialdehyde concentration in rice leaves. With leaf folder infestation, activities of the defense-related enzymes increased and malondialdehyde concentration decreased in plants amended with Si. Soluble protein content increased with Si addition when the plants were not infested, but was reduced more in the infested plants with Si amendment than in those without Si addition. Regardless of leaf folder infestation, Si amendment significantly increased leaf Si content through increases in the number and width of silica cells. Our results show that Si addition enhances rice resistance to the leaf folder through priming the feeding stress defense system, reduction in soluble protein content and cell silicification of rice leaves. PMID:27124300

How To: Create and Use Macros

ERIC Educational Resources Information Center

Branzburg, Jeffrey

2005-01-01

How often do people find themselves typing the same information, such as school names and addresses, into document after document? Or using the same sequence of menu commands, such as saving a file in a specific folder (File, Save, navigate to the folder, open the folder, save the file)? People would rather use a short key combination that…

5 CFR 293.306 - Use of existing folders upon transfer or reemployment.

Code of Federal Regulations, 2010 CFR

2010-01-01

... so obtained shall be used in lieu of establishing a new OPF. In the event that the prior service... to the new employing agency. (b) Before transferring the Official Personnel Folder, the losing agency shall: (1) Remove those records of a temporary nature filed on the left side of the folder, except for...

5 CFR 293.306 - Use of existing folders upon transfer or reemployment.

Code of Federal Regulations, 2011 CFR

2011-01-01

... so obtained shall be used in lieu of establishing a new OPF. In the event that the prior service... to the new employing agency. (b) Before transferring the Official Personnel Folder, the losing agency shall: (1) Remove those records of a temporary nature filed on the left side of the folder, except for...

Development of a data mining and imaging informatics display tool for a multiple sclerosis e-folder system

NASA Astrophysics Data System (ADS)

Liu, Margaret; Loo, Jerry; Ma, Kevin; Liu, Brent

2011-03-01

Multiple sclerosis (MS) is a debilitating autoimmune disease of the central nervous system that damages axonal pathways through inflammation and demyelination. In order to address the need for a centralized application to manage and study MS patients, the MS e-Folder - a web-based, disease-specific electronic medical record system - was developed. The e-Folder has a PHP and MySQL based graphical user interface (GUI) that can serve as both a tool for clinician decision support and a data mining tool for researchers. This web-based GUI gives the e-Folder a user friendly interface that can be securely accessed through the internet and requires minimal software installation on the client side. The e-Folder GUI displays and queries patient medical records--including demographic data, social history, past medical history, and past MS history. In addition, DICOM format imaging data, and computer aided detection (CAD) results from a lesion load algorithm are also displayed. The GUI interface is dynamic and allows manipulation of the DICOM images, such as zoom, pan, and scrolling, and the ability to rotate 3D images. Given the complexity of clinical management and the need to bolster research in MS, the MS e-Folder system will improve patient care and provide MS researchers with a function-rich patient data hub.

SeCD electronic folder: CADMIO's application for the medical folder of a service for the care of drug addicts.

PubMed

Della Valle, R M; Baldoni, A; De Rossi, M; Ferri, F

1998-01-01

In this paper we will describe the SeCD (Service for the Care of Drug addicts) electronic folder, a specific application of CADMIO [1] (Computer Aided Design for Medical Information Objects) system. CADMIO is a system for the definition, construction and management of multimedia clinical folders. The Ser.T. (Servizio per la Tossicodipendenza/Service for Drug Addicts) has earned a very special place within the Italian clinical structures as well as any service for drug addicts has done in the rest of the world. Such a structure has special needs and the characteristics of its medical folders are very different from any other folder. Actually, a Ser.T. has to keep updated the patient situation either from the clinical point of view as well as the psychiatric one. Moreover, it must keep track of the clinician subjective considerations about the patient psychic state and his situation in regard of the law. So, we had to redesign some of the features of the existing CADMIO application, to accommodate such highly not structured data into objects easily manipulated by an informative system. The objectives we hope to achieve were mainly two: To show that a well designed adaptive system can be easily exploited to support even very complex and poorly structured data types and actions To design data structures able to accommodate medical, psychiatric and administrative data in an homogeneous manner.

Fatigue design of a cellular phone folder using regression model-based multi-objective optimization

NASA Astrophysics Data System (ADS)

Kim, Young Gyun; Lee, Jongsoo

2016-08-01

In a folding cellular phone, the folding device is repeatedly opened and closed by the user, which eventually results in fatigue damage, particularly to the front of the folder. Hence, it is important to improve the safety and endurance of the folder while also reducing its weight. This article presents an optimal design for the folder front that maximizes its fatigue endurance while minimizing its thickness. Design data for analysis and optimization were obtained experimentally using a test jig. Multi-objective optimization was carried out using a nonlinear regression model. Three regression methods were employed: back-propagation neural networks, logistic regression and support vector machines. The AdaBoost ensemble technique was also used to improve the approximation. Two-objective Pareto-optimal solutions were identified using the non-dominated sorting genetic algorithm (NSGA-II). Finally, a numerically optimized solution was validated against experimental product data, in terms of both fatigue endurance and thickness index.

6. Photocopied August 1971 from Photo 13731, Granite Folder #1, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

6. Photocopied August 1971 from Photo 13731, Granite Folder #1, Engineering Department, Utah Power and Light Co., Salt Lake City, Utah. GRANITE STATION, MAY 24, 1915. - Utah Power Company, Granite Hydroelectric Plant, Holladay, Salt Lake County, UT

1. Photocopied from Photo 1645, Wheelon Station Folder #1, Engineering ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. Photocopied from Photo 1645, Wheelon Station Folder #1, Engineering Department, Utah Power & Light Co., Salt Lake City, Utah. UTAH SUGAR CO.'S DAM -- BEAR RIVER CANYON. - Irrigation Diversion Canal, Bear River, Fielding, Box Elder County, UT

5 CFR 293.303 - Ownership of folder.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Ownership of folder. 293.303 Section 293.303 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL... the records of, the Office of Personnel Management (the Office). ...

5 CFR 293.303 - Ownership of folder.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Ownership of folder. 293.303 Section 293.303 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL... the records of, the Office of Personnel Management (the Office). ...

77 FR 50532 - Agency Information Collection Activities: Proposed Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-21

... NATIONAL ARCHIVES AND RECORDS ADMINISTRATION Agency Information Collection Activities: Proposed Collection; Comment Request AGENCY: National Archives and Records Administration (NARA). ACTION: Notice... Personnel Folders or Employee Medical Folders from the National Personnel Records Center (NPRC) of the...

New Record Folder for Use in General Practice

PubMed Central

Hawkey, J. K.; Loudon, I. S. L.; Greenhalgh, G. P.; Bungay, G. T.

1971-01-01

A new concept for filing medical records in general practice is described, based on an A4-size folder; in experimental use in 40 practices doctors were generally in favour of the new system. ImagesFIG. 1FIG. 2 PMID:5134567

10. Photocopied from Photo 1162, Nunns Station Folder, Engineering Department, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

10. Photocopied from Photo 1162, Nunns Station Folder, Engineering Department, Utah Power & Light Co., Salt Lake City, Utah. PENSTOCKS, c. 1920? - Telluride Power Company, Nunn Hydroelectric Plant, Southeast side of Provo River, 300 feet West of US Route 189, Orem, Utah County, UT

26. Photocopied from Photo 1217, Olmstead Folder #2, Engineering Department, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

26. Photocopied from Photo 1217, Olmstead Folder #2, Engineering Department, Utah Power & Light Co., Salt Lake City, Utah. MACHINE SHOP -- LAB. - Telluride Power Company, Olmsted Hydroelectric Plant, mouth of Provo River Canyon West of U.S. Route 189, Orem, Utah County, UT

27. Photocopied from Photo 1216, Olmstead Folder #2, Engineering Department, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

27. Photocopied from Photo 1216, Olmstead Folder #2, Engineering Department, Utah Power & Light Co., Salt Lake City, Utah. MACHINE SHOP -- LAB. - Telluride Power Company, Olmsted Hydroelectric Plant, mouth of Provo River Canyon West of U.S. Route 189, Orem, Utah County, UT

5 CFR 293.510 - Disposition of Employee Medical Folders.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Disposition of Employee Medical Folders. 293.510 Section 293.510 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL RECORDS Employee Medical File System Records § 293.510 Disposition of Employee Medical...

5 CFR 293.510 - Disposition of Employee Medical Folders.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 5 Administrative Personnel 1 2012-01-01 2012-01-01 false Disposition of Employee Medical Folders. 293.510 Section 293.510 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL RECORDS Employee Medical File System Records § 293.510 Disposition of Employee Medical...

5 CFR 293.510 - Disposition of Employee Medical Folders.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Disposition of Employee Medical Folders. 293.510 Section 293.510 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL RECORDS Employee Medical File System Records § 293.510 Disposition of Employee Medical...

5 CFR 293.510 - Disposition of Employee Medical Folders.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false Disposition of Employee Medical Folders. 293.510 Section 293.510 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL RECORDS Employee Medical File System Records § 293.510 Disposition of Employee Medical...

5 CFR 293.510 - Disposition of Employee Medical Folders.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Disposition of Employee Medical Folders. 293.510 Section 293.510 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL RECORDS Employee Medical File System Records § 293.510 Disposition of Employee Medical...

3. Photocopied July 1971 from Photo 741, Jordan Narrows Folder ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. Photocopied July 1971 from Photo 741, Jordan Narrows Folder #1, Engineering Department, Utah Power and Light Co., Salt Lake City, Utah. INTERIOR VIEW, JULY 2, 1909. - Salt Lake City Water & Electrical Power Company, Jordan Narrows Hydroelectric Plant, Jordan River, Riverton, Salt Lake County, UT

2. Photocopied July 1971 from photostat Jordan Narrows Folder #1, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. Photocopied July 1971 from photostat Jordan Narrows Folder #1, Engineering Department, Utah Power and Light Co., Salt Lake City, Utah. JORDAN NARROWS STATION. PLAN AND SECTION. - Salt Lake City Water & Electrical Power Company, Jordan Narrows Hydroelectric Plant, Jordan River, Riverton, Salt Lake County, UT

28. Photocopied from Photo 588 OLM, Olmstead Folder #1, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

28. Photocopied from Photo 588 - OLM, Olmstead Folder #1, Engineering Department, Utah Power & Light Co., Salt Lake City, Utah. STATION INTERIOR, DECEMBER 5, 1908. - Telluride Power Company, Olmsted Hydroelectric Plant, mouth of Provo River Canyon West of U.S. Route 189, Orem, Utah County, UT

8. Photocopied from unnumbered photo, Nunns Station Folder, Engineering Department, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

8. Photocopied from unnumbered photo, Nunns Station Folder, Engineering Department, Utah Power & Light Co., Salt Lake City, Utah. EXTERIOR VIEW. C. 1898. - Telluride Power Company, Nunn Hydroelectric Plant, Southeast side of Provo River, 300 feet West of US Route 189, Orem, Utah County, UT

11. Photocopied from Photo #1, Nunns Station Folder, Engineering Department, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

11. Photocopied from Photo #1, Nunns Station Folder, Engineering Department, Utah Power & Light Co., Salt Lake City, Utah. 'INTERIOR NUNNS STATION.' c. 1898. - Telluride Power Company, Nunn Hydroelectric Plant, Southeast side of Provo River, 300 feet West of US Route 189, Orem, Utah County, UT

5 CFR 293.505 - Establishment and protection of Employee Medical Folder.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false Establishment and protection of Employee Medical Folder. 293.505 Section 293.505 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL RECORDS Employee Medical File System Records § 293.505 Establishment and...

5 CFR 293.505 - Establishment and protection of Employee Medical Folder.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Establishment and protection of Employee Medical Folder. 293.505 Section 293.505 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL RECORDS Employee Medical File System Records § 293.505 Establishment and...

5 CFR 293.505 - Establishment and protection of Employee Medical Folder.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Establishment and protection of Employee Medical Folder. 293.505 Section 293.505 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL RECORDS Employee Medical File System Records § 293.505 Establishment and...

5 CFR 293.505 - Establishment and protection of Employee Medical Folder.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Establishment and protection of Employee Medical Folder. 293.505 Section 293.505 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL RECORDS Employee Medical File System Records § 293.505 Establishment and...

5 CFR 293.505 - Establishment and protection of Employee Medical Folder.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 5 Administrative Personnel 1 2012-01-01 2012-01-01 false Establishment and protection of Employee Medical Folder. 293.505 Section 293.505 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL RECORDS Employee Medical File System Records § 293.505 Establishment and...

76 FR 22682 - Privacy Act of 1974; System of Records

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-22

...: Maintained in file folders and computer storage media. Retrievability: Retrieved by name and/or Social... folders and computer storage media.'' * * * * * System Manager(s) and address: Delete entry and replace... provide their full name, Social Security Number (SSN), any details which may assist in locating records...

The development of a disease oriented eFolder for multiple sclerosis decision support

NASA Astrophysics Data System (ADS)

Ma, Kevin; Jacobs, Colin; Fernandez, James; Amezcua, Lilyana; Liu, Brent

2010-03-01

Multiple sclerosis (MS) is a demyelinating disease of the central nervous system. The chronic nature of MS necessitates multiple MRI studies to track disease progression. Currently, MRI assessment of multiple sclerosis requires manual lesion measurement and yields an estimate of lesion volume and change that is highly variable and user-dependent. In the setting of a longitudinal study, disease trends and changes become difficult to extrapolate from the lesions. In addition, it is difficult to establish a correlation between these imaged lesions and clinical factors such as treatment course. To address these clinical needs, an MS specific e-Folder for decision support in the evaluation and assessment of MS has been developed. An e-Folder is a disease-centric electronic medical record in contrast to a patient-centric electronic health record. Along with an MS lesion computer aided detection (CAD) package for lesion load, location, and volume, clinical parameters such as patient demographics, disease history, clinical course, and treatment history are incorporated to make the e-Folder comprehensive. With the integration of MRI studies together with related clinical data and informatics tools designed for monitoring multiple sclerosis, it provides a platform to improve the detection of treatment response in patients with MS. The design and deployment of MS e-Folder aims to standardize MS lesion data and disease progression to aid in decision making and MS-related research.

Temperature Thresholds and Thermal Requirements for the Development of the Rice Leaf Folder, Cnaphalocrocis medinalis

PubMed Central

Padmavathi, Chintalapati; Katti, Gururaj; Sailaja, V.; Padmakumari, A.P.; Jhansilakshmi, V.; Prabhakar, M.; Prasad, Y.G.

2013-01-01

The rice leaf folder, Cnaphalocrocis medinalis Guenée (Lepidoptera: Pyralidae) is a predominant foliage feeder in all the rice ecosystems. The objective of this study was to examine the development of leaf folder at 7 constant temperatures (18, 20, 25, 30, 32, 34, 35° C) and to estimate temperature thresholds and thermal constants for the forecasting models based on heat accumulation units, which could be developed for use in forecasting. The developmental periods of different stages of rice leaf folder were reduced with increases in temperature from 18 to 34° C. The lower threshold temperatures of 11.0, 10.4, 12.8, and 11.1° C, and thermal constants of 69, 270, 106, and 455 degree days, were estimated by linear regression analysis for egg, larva, pupa, and total development, respectively. Based on the thermodynamic non-linear optimSSI model, intrinsic optimum temperatures for the development of egg, larva, and pupa were estimated at 28.9, 25.1 and 23.7° C, respectively. The upper and lower threshold temperatures were estimated as 36.4° C and 11.2° C for total development, indicating that the enzyme was half active and half inactive at these temperatures. These estimated thermal thresholds and degree days could be used to predict the leaf folder activity in the field for their effective management. PMID:24205891

1. Photocopied July 1971 from Photo 745, Jordan Narrows Folder ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. Photocopied July 1971 from Photo 745, Jordan Narrows Folder #1, Engineering Department, Utah Power and Light Co., Salt Lake City, Utah. JORDAN STATION, JULY 2, 1909. GENERAL VIEW. - Salt Lake City Water & Electrical Power Company, Jordan Narrows Hydroelectric Plant, Jordan River, Riverton, Salt Lake County, UT

9. Photocopied August 1971 from Photo 13730, Granite Folder #1, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

9. Photocopied August 1971 from Photo 13730, Granite Folder #1, Engineering Department, Utah Power and Light Co., Salt Lake City, Utah. GRANITE STATION: WESTINGHOUSE 750 K.V.A., 2- PHASE GENERATORS AND SWITCHBOARD, MAY 24, 1915. - Utah Power Company, Granite Hydroelectric Plant, Holladay, Salt Lake County, UT

9. Photocopied from Photo 1161, Nunns Station Folder, Engineering Department, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

9. Photocopied from Photo 1161, Nunns Station Folder, Engineering Department, Utah Power & Light Co., Salt Lake City, Utah. VIEW OF SITE SHOWING PENSTOCKS. c. 1920.? - Telluride Power Company, Nunn Hydroelectric Plant, Southeast side of Provo River, 300 feet West of US Route 189, Orem, Utah County, UT

23. Photocopied from Photo 664OLM, Olmstead Folder #1, Engineering Department, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

23. Photocopied from Photo 664-OLM, Olmstead Folder #1, Engineering Department, Utah Power & Light Co., Salt Lake City, Utah. INTERIOR OF STATION, APRIL 8, 1909. - Telluride Power Company, Olmsted Hydroelectric Plant, mouth of Provo River Canyon West of U.S. Route 189, Orem, Utah County, UT

21. Photocopied from blueprint, Olmstead Station Miscellaneous Drawings Folder, Engineering ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

21. Photocopied from blueprint, Olmstead Station Miscellaneous Drawings Folder, Engineering Department, Utah Power & Light Co., Salt Lake City, Utah. 'STATION GROUNDS, TELLURIDE POWER CO., PROVO, UTAH.' MAP,1903. - Telluride Power Company, Olmsted Hydroelectric Plant, mouth of Provo River Canyon West of U.S. Route 189, Orem, Utah County, UT

22. Photocopied from Photo 505OLM, Olmstead Folder #1, Engineering Department, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

22. Photocopied from Photo 505-OLM, Olmstead Folder #1, Engineering Department, Utah Power & Light Co., Salt Lake City, Utah. OLD PENSTOCKS, JANUARY 25, 1908. - Telluride Power Company, Olmsted Hydroelectric Plant, mouth of Provo River Canyon West of U.S. Route 189, Orem, Utah County, UT

24. Photocopied from Photo 669OLM, Olmstead Folder #1, Engineering Department, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

24. Photocopied from Photo 669-OLM, Olmstead Folder #1, Engineering Department, Utah Power & Light Co., Salt Lake City, Utah. NEW PENSTOCK, APRIL 8, 1909. - Telluride Power Company, Olmsted Hydroelectric Plant, mouth of Provo River Canyon West of U.S. Route 189, Orem, Utah County, UT

2. Photocopied from Photo 11456, Wheelon Station Special Folder, Engineering ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. Photocopied from Photo 11456, Wheelon Station Special Folder, Engineering Dept., Utah Power & Light Co., Salt Lake City, Utah. 'WHEELON HYDRO-ELECTRIC PLANT (7125 KW). INTERIOR OF MAIN BUILDING SHOWING FOUR 1000 KW UNITS. NOV 1914.' - Utah Sugar Company, Wheelon Hydoelectric Plant, Bear River, Fielding, Box Elder County, UT

5 CFR 293.507 - Maintenance and content of the Employee Medical Folder.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 5 Administrative Personnel 1 2012-01-01 2012-01-01 false Maintenance and content of the Employee Medical Folder. 293.507 Section 293.507 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL RECORDS Employee Medical File System Records § 293.507 Maintenance and...

5 CFR 293.507 - Maintenance and content of the Employee Medical Folder.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Maintenance and content of the Employee Medical Folder. 293.507 Section 293.507 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL RECORDS Employee Medical File System Records § 293.507 Maintenance and...

5 CFR 293.506 - Ownership of the Employee Medical Folder.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Ownership of the Employee Medical Folder. 293.506 Section 293.506 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL RECORDS Employee Medical File System Records § 293.506 Ownership of the Employee Medical...

5 CFR 293.506 - Ownership of the Employee Medical Folder.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false Ownership of the Employee Medical Folder. 293.506 Section 293.506 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL RECORDS Employee Medical File System Records § 293.506 Ownership of the Employee Medical...

5 CFR 293.506 - Ownership of the Employee Medical Folder.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 5 Administrative Personnel 1 2012-01-01 2012-01-01 false Ownership of the Employee Medical Folder. 293.506 Section 293.506 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL RECORDS Employee Medical File System Records § 293.506 Ownership of the Employee Medical...

5 CFR 293.507 - Maintenance and content of the Employee Medical Folder.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Maintenance and content of the Employee Medical Folder. 293.507 Section 293.507 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL RECORDS Employee Medical File System Records § 293.507 Maintenance and...

5 CFR 293.507 - Maintenance and content of the Employee Medical Folder.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Maintenance and content of the Employee Medical Folder. 293.507 Section 293.507 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL RECORDS Employee Medical File System Records § 293.507 Maintenance and...

5 CFR 293.507 - Maintenance and content of the Employee Medical Folder.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false Maintenance and content of the Employee Medical Folder. 293.507 Section 293.507 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL RECORDS Employee Medical File System Records § 293.507 Maintenance and...

5 CFR 293.506 - Ownership of the Employee Medical Folder.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Ownership of the Employee Medical Folder. 293.506 Section 293.506 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL RECORDS Employee Medical File System Records § 293.506 Ownership of the Employee Medical...

5 CFR 293.506 - Ownership of the Employee Medical Folder.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Ownership of the Employee Medical Folder. 293.506 Section 293.506 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL RECORDS Employee Medical File System Records § 293.506 Ownership of the Employee Medical...

Transported Geothermal Energy Technoeconomic Screening Tool - Calculation Engine

DOE Data Explorer

Liu, Xiaobing

2016-09-21

This calculation engine estimates technoeconomic feasibility for transported geothermal energy projects. The TGE screening tool (geotool.exe) takes input from input file (input.txt), and list results into output file (output.txt). Both the input and ouput files are in the same folder as the geotool.exe. To use the tool, the input file containing adequate information of the case should be prepared in the format explained below, and the input file should be put into the same folder as geotool.exe. Then the geotool.exe can be executed, which will generate a output.txt file in the same folder containing all key calculation results. The format and content of the output file is explained below as well.

Who's Zooming Whom? Attunement to Animation in the Interface.

ERIC Educational Resources Information Center

Chui, Michael; Dillon, Andrew

1997-01-01

Two controlled experiments examined whether the animated zooming effect accompanying the opening or closing of a folder in the Apple Macintosh graphical user interface aids in the user's perception of which window corresponds to which folder. Results suggest users may become attuned to the informational content of the zooming effect with…

7. Photocopied from Dwg. 69, Nunns Station Folder, Engineering Department, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

7. Photocopied from Dwg. 69, Nunns Station Folder, Engineering Department, Utah Power & Light Co., Salt Lake City, Utah. FLOOR PLANT. (POWER HOUSE IN PROVO CANYON, PROVO, UTAH?) c. 1900. - Telluride Power Company, Nunn Hydroelectric Plant, Southeast side of Provo River, 300 feet West of US Route 189, Orem, Utah County, UT

6. Photocopied from unnumbered drawing, Drawings folder, Engineering Department, Utah ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

6. Photocopied from unnumbered drawing, Drawings folder, Engineering Department, Utah Power & Light Co., Salt Lake City, Utah. 'THE TELLURIDE POWER CO. LABORATORY EXTENSION. SOUTH ELEVATION. PROVO, UTAH. NOV. 9, 1909.' - Telluride Power Company, Nunn Hydroelectric Plant, Southeast side of Provo River, 300 feet West of US Route 189, Orem, Utah County, UT

Solid Waste/Energy Curriculum.

ERIC Educational Resources Information Center

Vivan, V. Eugene; And Others

Provided are solid waste/energy curriculum materials for grades K-2, 3-4, 5-6, 7-9, and 10-12. Separate folders containing units of study (focusing on trash, litter, and recycling) are provided for kindergarten (four units), grade 1 (two units), and grade 2 (two units). Folders contain teachers' directions and activity cards which include picture…

5 CFR 293.509 - Use of existing Employee Medical Folders upon transfer or reemployment.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Use of existing Employee Medical Folders upon transfer or reemployment. 293.509 Section 293.509 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL RECORDS Employee Medical File System Records § 293.509 Use of...

5 CFR 293.509 - Use of existing Employee Medical Folders upon transfer or reemployment.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 5 Administrative Personnel 1 2012-01-01 2012-01-01 false Use of existing Employee Medical Folders upon transfer or reemployment. 293.509 Section 293.509 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL RECORDS Employee Medical File System Records § 293.509 Use of...

5 CFR 293.509 - Use of existing Employee Medical Folders upon transfer or reemployment.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Use of existing Employee Medical Folders upon transfer or reemployment. 293.509 Section 293.509 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL RECORDS Employee Medical File System Records § 293.509 Use of...

5 CFR 293.509 - Use of existing Employee Medical Folders upon transfer or reemployment.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Use of existing Employee Medical Folders upon transfer or reemployment. 293.509 Section 293.509 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL RECORDS Employee Medical File System Records § 293.509 Use of...

5 CFR 293.509 - Use of existing Employee Medical Folders upon transfer or reemployment.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false Use of existing Employee Medical Folders upon transfer or reemployment. 293.509 Section 293.509 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL RECORDS Employee Medical File System Records § 293.509 Use of...

Strategies for Keeping Papers Organized.

ERIC Educational Resources Information Center

Dwyer, Edward J.

1989-01-01

The amount of paperwork in teaching often seems overwhelming. This being the case, organization is essential for effective teaching. Several ideas for dealing with paper flow are useful. Box file folders or durable plastic file cases, plus an ample supply of file folders, are excellent for storing papers. Papers used in a particular class can be…

Science Air and Space: Folder Games for the Classroom.

ERIC Educational Resources Information Center

Hughes, Leah M.

A file folder, the drawings contained within this book, and materials such as crayons, glue, and straws are what is needed to make this resource a classroom tool for studying space-related topics with preschoolers. The activities in this book are designed to inspire preschoolers to use their creativity, inventiveness, imagination, and intuition.…

Evaluation of longitudinal tracking and data mining for an imaging informatics-based multiple sclerosis e-folder (Conference Presentation)

NASA Astrophysics Data System (ADS)

Ma, Kevin C.; Forsyth, Sydney; Amezcua, Lilyana; Liu, Brent J.

2017-03-01

We have designed and developed a multiple sclerosis eFolder system for patient data storage, image viewing, and automatic lesion quantification results to allow patient tracking. The web-based system aims to be integrated in DICOM-compliant clinical and research environments to aid clinicians in patient treatments and data analysis. The system quantifies lesion volumes, identify and register lesion locations to track shifts in volume and quantity of lesions in a longitudinal study. We aim to evaluate the two most important features of the system, data mining and longitudinal lesion tracking, to demonstrate the MS eFolder's capability in improving clinical workflow efficiency and outcome analysis for research. In order to evaluate data mining capabilities, we have collected radiological and neurological data from 72 patients, 36 Caucasian and 36 Hispanic matched by gender, disease duration, and age. Data analysis on those patients based on ethnicity is performed, and analysis results are displayed by the system's web-based user interface. The data mining module is able to successfully separate Hispanic and Caucasian patients and compare their disease profiles. For longitudinal lesion tracking, we have collected 4 longitudinal cases and simulated different lesion growths over the next year. As a result, the eFolder is able to detect changes in lesion volume and identifying lesions with the most changes. Data mining and lesion tracking evaluation results show high potential of eFolder's usefulness in patientcare and informatics research for multiple sclerosis.

5. Photocopied from drawing 70, Nunns Station Folder, Engineering Department, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

5. Photocopied from drawing 70, Nunns Station Folder, Engineering Department, Utah Power & Light Co., Salt Lake City, Utah. 'TILE TELLURIDE POWER TRANSMISSION CO. POWER HOUSE IN PROVO CANYON, PROVO, UTAH' SECTION, c. 1900. - Telluride Power Company, Nunn Hydroelectric Plant, Southeast side of Provo River, 300 feet West of US Route 189, Orem, Utah County, UT

Family Food Choices: A Guide to Weight and Diabetes Control.

ERIC Educational Resources Information Center

Indian Health Service (PHS/HSA), Rockville, MD.

Written for American Indians who have diabetes, this folder explains diabetes and outlines a weight control program and diet. The folder discusses the five things diabetics can do to help control their disease: lose weight, watch the amount and kind of fat eaten, eat more food with fiber, avoid sugar, and avoid alcohol. Charts for foods containing…

36 CFR 1233.16 - How does an agency transfer records to the National Personnel Records Center (NPRC)?

Code of Federal Regulations, 2011 CFR

2011-07-01

... employee medical folder (EMF) to the NPRC at the same time. (2) Transfer EMFs and OPFs in separate folders... 36 Parks, Forests, and Public Property 3 2011-07-01 2011-07-01 false How does an agency transfer... Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION RECORDS MANAGEMENT TRANSFER, USE, AND...

75 FR 57333 - Privacy Act of 1974; Republication of Systems of Records Notices

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-20

... file folders and on electronic media. RETRIEVABILITY: Accessed by name, tag number, and/or permit... file folders and on electronic media. RETRIEVABILITY: Records are accessed by name. SAFEGUARDS: Records... SYSTEM: 5 CFR 2634-2641, 5801; 5 U.S.C. 7351, 7353; Ethics in Government Act of 1978, as amended (5 U.S.C...

Sequence repeats and protein structure

NASA Astrophysics Data System (ADS)

Hoang, Trinh X.; Trovato, Antonio; Seno, Flavio; Banavar, Jayanth R.; Maritan, Amos

2012-11-01

Repeats are frequently found in known protein sequences. The level of sequence conservation in tandem repeats correlates with their propensities to be intrinsically disordered. We employ a coarse-grained model of a protein with a two-letter amino acid alphabet, hydrophobic (H) and polar (P), to examine the sequence-structure relationship in the realm of repeated sequences. A fraction of repeated sequences comprises a distinct class of bad folders, whose folding temperatures are much lower than those of random sequences. Imperfection in sequence repetition improves the folding properties of the bad folders while deteriorating those of the good folders. Our results may explain why nature has utilized repeated sequences for their versatility and especially to design functional proteins that are intrinsically unstructured at physiological temperatures.

Identification and comparative expression profiles of chemoreception genes revealed from major chemoreception organs of the rice leaf folder, Cnaphalocrocis medinalis (Lepidoptera: Pyralidae)

USDA-ARS?s Scientific Manuscript database

To better understand the olfactory mechanism in the rice leaf folder, Cnaphalocrocis medinalis (Guenée), one of the most serious insect pests of rice in Asia, we have established six partial transcriptomes from antennae, tarsus, and reproductive organs of male and female adults. A total of 102 genes...

25. Photocopied from Photo 1103, Olmstead Folder #2, Engineering Department, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

25. Photocopied from Photo 1103, Olmstead Folder #2, Engineering Department, Utah Power & Light Co., Salt Lake City, Utah. GENERAL VIEW OF SITE, c.1920? (PHOTO SHOWS DENVER & RIO GRANDE WESTERN RR BRIDGE, MOVED TO SITE IN 1919.) - Telluride Power Company, Olmsted Hydroelectric Plant, mouth of Provo River Canyon West of U.S. Route 189, Orem, Utah County, UT

Economic impact of off-line PC viewer for private folder management

NASA Astrophysics Data System (ADS)

Song, Koun-Sik; Shin, Myung J.; Lee, Joo Hee; Auh, Yong H.

1999-07-01

We developed a PC-based clinical workstation and implemented at Asan Medical Center in Seoul, Korea, Hardwares used were Pentium-II, 8M video memory, 64-128 MB RAM, 19 inch color monitor, and 10/100Mbps network adaptor. One of the unique features of this workstation is management tool for folders reside both in PACS short-term storage unit and local hard disk. Users can copy the entire study or part of the study to local hard disk, removable storages, or CD recorder. Even the images in private folders in PACS short-term storage can be copied to local storage devices. All images are saved as DICOM 3.0 file format with 2:1 lossless compression. We compared the prices of copy films and storage medias considering the possible savings of expensive PACS short- term storage and network traffic. Price savings of copy film is most remarkable in MR exam. Price savings arising from minimal use of short-term unit was 50,000 dollars. It as hard to calculate the price savings arising from the network usage. Off-line PC viewer is a cost-effective way of handling private folder management under the PACS environment.

Auditing chronic disease care: Does it make a difference?

PubMed

Essel, Vivien; van Vuuren, Unita; De Sa, Angela; Govender, Srini; Murie, Katie; Schlemmer, Arina; Gunst, Colette; Namane, Mosedi; Boulle, Andrew; de Vries, Elma

2015-06-26

An integrated audit tool was developed for five chronic diseases, namely diabetes, hypertension, asthma, chronic obstructive pulmonary disease and epilepsy. Annual audits have been done in the Western Cape Metro district since 2009. The year 2012 was the first year that all six districts in South Africa's Western Cape Province participated in the audit process. To determine whether clinical audits improve chronic disease care in health districts over time. Western Cape Province, South Africa. Internal audits were conducted of primary healthcare facility processes and equipment availability as well as a folder review of 10 folders per chronic condition per facility. Random systematic sampling was used to select the 10 folders for the folder review. Combined data for all facilities gave a provincial overview and allowed for comparison between districts. Analysis was done comparing districts that have been participating in the audit process from 2009 to 2010 ('2012 old') to districts that started auditing recently ('2012 new'). The number of facilities audited has steadily increased from 29 in 2009 to 129 in 2012. Improvements between different years have been modest, and the overall provincial average seemed worse in 2012 compared to 2011. However, there was an improvement in the '2012 old' districts compared to the '2012 new' districts for both the facility audit and the folder review, including for eight clinical indicators, with '2012 new' districts being less likely to record clinical processes (OR 0.25, 95% CI 0.21-0.31). These findings are an indication of the value of audits to improve care processes over the long term. It is hoped that this improvement will lead to improved patient outcomes.

Auditing chronic disease care: Does it make a difference?

PubMed Central

van Vuuren, Unita; De Sa, Angela; Govender, Srini; Murie, Katie; Schlemmer, Arina; Gunst, Colette; Namane, Mosedi; Boulle, Andrew; de Vries, Elma

2015-01-01

Background An integrated audit tool was developed for five chronic diseases, namely diabetes, hypertension, asthma, chronic obstructive pulmonary disease and epilepsy. Annual audits have been done in the Western Cape Metro district since 2009. The year 2012 was the first year that all six districts in South Africa's Western Cape Province participated in the audit process. Aim To determine whether clinical audits improve chronic disease care in health districts over time. Setting Western Cape Province, South Africa. Methods Internal audits were conducted of primary healthcare facility processes and equipment availability as well as a folder review of 10 folders per chronic condition per facility. Random systematic sampling was used to select the 10 folders for the folder review. Combined data for all facilities gave a provincial overview and allowed for comparison between districts. Analysis was done comparing districts that have been participating in the audit process from 2009 to 2010 (‘2012 old’) to districts that started auditing recently (‘2012 new’). Results The number of facilities audited has steadily increased from 29 in 2009 to 129 in 2012. Improvements between different years have been modest, and the overall provincial average seemed worse in 2012 compared to 2011. However, there was an improvement in the ‘2012 old’ districts compared to the ‘2012 new’ districts for both the facility audit and the folder review, including for eight clinical indicators, with ‘2012 new’ districts being less likely to record clinical processes (OR 0.25, 95% CI 0.21–0.31). Conclusion These findings are an indication of the value of audits to improve care processes over the long term. It is hoped that this improvement will lead to improved patient outcomes. PMID:26245615

[Personal health records: the case of the Personal Health Folder of Catalonia (Spain)].

PubMed

Saigí, Francesc; Cerdá Calafat, Ismael; Guanyabens Calvet, Joan; Carrau Vidal, Elisenda

2012-01-01

The aims of this study were to explore the possibilities of the Personal Health Folder and to identify the gap between the potential applications of this tool and what it offers through the Internet. The Personal Health Folder is presented, a project linked to the Shared Medical Record of Catalonia (Spain), which provides citizens with an access point to information about their health insurance, customized and supported by information and communication technologies. The project was carried out by the Ministry of Health of the Government of Catalonia (Generalitat de Catalunya) and data were gathered through an anonymous survey. The results were critical to obtain information on the suitability of the published data and on the expectations of a tool aimed at the general population. Copyright © 2012 SESPAS. Published by Elsevier Espana. All rights reserved.

Design and development of an ethnically-diverse imaging informatics-based eFolder system for multiple sclerosis patients.

PubMed

Ma, Kevin C; Fernandez, James R; Amezcua, Lilyana; Lerner, Alex; Shiroishi, Mark S; Liu, Brent J

2015-12-01

MRI has been used to identify multiple sclerosis (MS) lesions in brain and spinal cord visually. Integrating patient information into an electronic patient record system has become key for modern patient care in medicine in recent years. Clinically, it is also necessary to track patients' progress in longitudinal studies, in order to provide comprehensive understanding of disease progression and response to treatment. As the amount of required data increases, there exists a need for an efficient systematic solution to store and analyze MS patient data, disease profiles, and disease tracking for both clinical and research purposes. An imaging informatics based system, called MS eFolder, has been developed as an integrated patient record system for data storage and analysis of MS patients. The eFolder system, with a DICOM-based database, includes a module for lesion contouring by radiologists, a MS lesion quantification tool to quantify MS lesion volume in 3D, brain parenchyma fraction analysis, and provide quantitative analysis and tracking of volume changes in longitudinal studies. Patient data, including MR images, have been collected retrospectively at University of Southern California Medical Center (USC) and Los Angeles County Hospital (LAC). The MS eFolder utilizes web-based components, such as browser-based graphical user interface (GUI) and web-based database. The eFolder database stores patient clinical data (demographics, MS disease history, family history, etc.), MR imaging-related data found in DICOM headers, and lesion quantification results. Lesion quantification results are derived from radiologists' contours on brain MRI studies and quantified into 3-dimensional volumes and locations. Quantified results of white matter lesions are integrated into a structured report based on DICOM-SR protocol and templates. The user interface displays patient clinical information, original MR images, and viewing structured reports of quantified results. The GUI also includes a data mining tool to handle unique search queries for MS. System workflow and dataflow steps has been designed based on the IHE post-processing workflow profile, including workflow process tracking, MS lesion contouring and quantification of MR images at a post-processing workstation, and storage of quantitative results as DICOM-SR in DICOM-based storage system. The web-based GUI is designed to display zero-footprint DICOM web-accessible data objects (WADO) and the SR objects. The MS eFolder system has been designed and developed as an integrated data storage and mining solution in both clinical and research environments, while providing unique features, such as quantitative lesion analysis and disease tracking over a longitudinal study. A comprehensive image and clinical data integrated database provided by MS eFolder provides a platform for treatment assessment, outcomes analysis and decision-support. The proposed system serves as a platform for future quantitative analysis derived automatically from CAD algorithms that can also be integrated within the system for individual disease tracking and future MS-related research. Ultimately the eFolder provides a decision-support infrastructure that can eventually be used as add-on value to the overall electronic medical record. Copyright © 2015 Elsevier Ltd. All rights reserved.

Design and development of an ethnically-diverse imaging informatics-based eFolder system for multiple sclerosis patients

PubMed Central

Ma, Kevin C.; Fernandez, James R.; Amezcua, Lilyana; Lerner, Alex; Shiroishi, Mark S.; Liu, Brent J.

2016-01-01

Purpose MRI has been used to identify multiple sclerosis (MS) lesions in brain and spinal cord visually. Integrating patient information into an electronic patient record system has become key for modern patient care in medicine in recent years. Clinically, it is also necessary to track patients' progress in longitudinal studies, in order to provide comprehensive understanding of disease progression and response to treatment. As the amount of required data increases, there exists a need for an efficient systematic solution to store and analyze MS patient data, disease profiles, and disease tracking for both clinical and research purposes. Method An imaging informatics based system, called MS eFolder, has been developed as an integrated patient record system for data storage and analysis of MS patients. The eFolder system, with a DICOM-based database, includes a module for lesion contouring by radiologists, a MS lesion quantification tool to quantify MS lesion volume in 3D, brain parenchyma fraction analysis, and provide quantitative analysis and tracking of volume changes in longitudinal studies. Patient data, including MR images, have been collected retrospectively at University of Southern California Medical Center (USC) and Los Angeles County Hospital (LAC). The MS eFolder utilizes web-based components, such as browser-based graphical user interface (GUI) and web-based database. The eFolder database stores patient clinical data (demographics, MS disease history, family history, etc.), MR imaging-related data found in DICOM headers, and lesion quantification results. Lesion quantification results are derived from radiologists' contours on brain MRI studies and quantified into 3-dimensional volumes and locations. Quantified results of white matter lesions are integrated into a structured report based on DICOM-SR protocol and templates. The user interface displays patient clinical information, original MR images, and viewing structured reports of quantified results. The GUI also includes a data mining tool to handle unique search queries for MS. System workflow and dataflow steps has been designed based on the IHE post-processing workflow profile, including workflow process tracking, MS lesion contouring and quantification of MR images at a post-processing workstation, and storage of quantitative results as DICOM-SR in DICOM-based storage system. The web-based GUI is designed to display zero-footprint DICOM web-accessible data objects (WADO) and the SR objects. Summary The MS eFolder system has been designed and developed as an integrated data storage and mining solution in both clinical and research environments, while providing unique features, such as quantitative lesion analysis and disease tracking over a longitudinal study. A comprehensive image and clinical data integrated database provided by MS eFolder provides a platform for treatment assessment, outcomes analysis and decision-support. The proposed system serves as a platform for future quantitative analysis derived automatically from CAD algorithms that can also be integrated within the system for individual disease tracking and future MS-related research. Ultimately the eFolder provides a decision-support infrastructure that can eventually be used as add-on value to the overall electronic medical record. PMID:26564667

Office of Strategic Services Training during World War II

DTIC Science & Technology

2010-06-01

First Central Intelligence Agency (Berkeley: University of California Press, 1972); Thomas F. Troy, Donovan and the CIA: A History of the...William E. Colby Papers, Box 14, Folder 7, Seeley G. Mudd Library, Princeton University, Princeton, New Jer- sey. 50. Gerald K. Haines, “Virginia...subject heading] 29 January 1945, 2–3, CIA Records (RG 263), Thomas Troy Files, Box 6, Folder 46, National Archives, II. In August 2008, the

Effectiveness Evaluation of Force Protection Training Using Computer-Based Instruction and X3d Simulation

DTIC Science & Technology

2007-09-01

behavior libraries selection box, Savage Tactics behavior sub-folder and hostile behavior sub-folder that contains the behavior that is being assigned to...21) applications. The interface allows users to select models (locations, friendly assets, hostile assets, neutral assets, etc) that will be used in...altitude, etc.) for each model and define their behaviors (friendly patrol craft, hostile explosive-laden vessel, etc). Once the models and their

Iraqi Perspectives Project. Saddam and Terrorism: Emerging Insights from Captured Iraqi Documents. Volume 1 (Redacted)

DTIC Science & Technology

2007-11-01

of embassy weapons caches. A summary of a related document folder (ISGP-2003- 00010399, 3 October 2000) includes inventories of weapons within the...senior Iraqis noted that after OPERATIO DESERT Fox (December 1998), Saddam became much more concerned for his personal security. Saddam isolated...of a 114-page report concerning IIS operations in the northern area of Iraq, 13 October 1995. Harmony document folder ISGP-2003-000 10399 - Inventories

Electronic Mail (E-Mail) Management and Use

DTIC Science & Technology

1999-03-01

age or date of birth ; present or 14 AFI33-119 1 MARCH 1999future assignments for overseas, or for routinely deployable or sensitive units; and office...Server Naming Convention. The DMS-AF primary (e.g., ESL® Primary, Lotus ® Hub, and Microsoft® Bridgehead) server and its backup must conform to the 8...determine if there is some benefit to establishing standard lower-level folder names which bases should adhere to. Standard public folders offer a

Lesion registration for longitudinal disease tracking in an imaging informatics-based multiple sclerosis eFolder

NASA Astrophysics Data System (ADS)

Ma, Kevin; Liu, Joseph; Zhang, Xuejun; Lerner, Alex; Shiroishi, Mark; Amezcua, Lilyana; Liu, Brent

2016-03-01

We have designed and developed a multiple sclerosis eFolder system for patient data storage, image viewing, and automatic lesion quantification results stored in DICOM-SR format. The web-based system aims to be integrated in DICOM-compliant clinical and research environments to aid clinicians in patient treatments and data analysis. The system needs to quantify lesion volumes, identify and register lesion locations to track shifts in volume and quantity of lesions in a longitudinal study. In order to perform lesion registration, we have developed a brain warping and normalizing methodology using Statistical Parametric Mapping (SPM) MATLAB toolkit for brain MRI. Patients' brain MR images are processed via SPM's normalization processes, and the brain images are analyzed and warped according to the tissue probability map. Lesion identification and contouring are completed by neuroradiologists, and lesion volume quantification is completed by the eFolder's CAD program. Lesion comparison results in longitudinal studies show key growth and active regions. The results display successful lesion registration and tracking over a longitudinal study. Lesion change results are graphically represented in the web-based user interface, and users are able to correlate patient progress and changes in the MRI images. The completed lesion and disease tracking tool would enable the eFolder to provide complete patient profiles, improve the efficiency of patient care, and perform comprehensive data analysis through an integrated imaging informatics system.

Turn over folders: a proven tool in succession management planning.

PubMed

Engells, Thomas E

2011-01-01

The dual challenges of succession management and succession management planning are considerable. A tool, the Turn over Folder, was introduced and described in detail as a useful first step in succession management planning. The adoption of that tool will not in itself produce a succession management plan, but it will orientate the organization and its members to the reality of succession management in all important leadership and critical positions. Succession management is an important consideration in all progressive organizations and well worth the effort.

CADMIO: computer aided design for medical information objects.

PubMed

Minarelli, D V; Ferri, F; Pisanelli, D M; Ricci, F L; Tittarelli, F

1995-01-01

The growth of the computational capability and the tools of graphic software is nowadays available in an integrated manner into the development environments, thus permitting the realization of tool kits capable of handling information that is complex and of different kinds such as the typical medical information. This has given a great impulse to the creation of electronic medical folders joining together with new and stimulating functionality with respect to the usual paper document [1]. In the present work, we propose a tool capable of defining a multimedia electronic medical folder and representing its architecture through a layout that is formed on the basis of the particular data types to be handled. This tool is capable of providing an integrated view of data that, even though they are close in cognitive sense, are often stored and represented apart in the practice. Different approaches to the browsing feature are giving within the system, thus the user can personalize the way of viewing the information stored into the folder or can let the system guide the browsing.

Effectiveness of web-based versus folder support interventions for young informal carers of persons with mental illness: a randomized controlled trial.

PubMed

Ali, Lilas; Krevers, Barbro; Sjöström, Nils; Skärsäter, Ingela

2014-03-01

Compare the impact of two interventions, a web-based support and a folder support, for young persons who care for people who suffer from mental illness. This study was a randomized control trial, following the CONSORT statements, which compared the impact of two interventions. Primary outcome variable was stress, and secondary outcome variables were caring situation, general self-efficacy, well-being, health, and quality of life of young informal carers (N=241). Data were collected in June 2010 to April 2011, with self-assessment questionnaires, comparing the two interventions and also to detect changes. The stress levels were high in both groups at baseline, but decreased in the folder group. The folder group had improvement in their caring situation (also different from the web group), general self-efficacy, well-being, and quality of life. The web group showed increase in well-being. Young informal carers who take on the responsibility for people close to them; suffer consequences on their own health. They live in a life-situation characterized by high stress and low well-being. This signals a need for support. The non-significant differences show that each intervention can be effective, and that it depends upon the individual's preferences. This highlights the importance of adopting person-centered approach, in which young persons can themselves choose support strategy. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

Big data in multiple sclerosis: development of a web-based longitudinal study viewer in an imaging informatics-based eFolder system for complex data analysis and management

NASA Astrophysics Data System (ADS)

Ma, Kevin; Wang, Ximing; Lerner, Alex; Shiroishi, Mark; Amezcua, Lilyana; Liu, Brent

2015-03-01

In the past, we have developed and displayed a multiple sclerosis eFolder system for patient data storage, image viewing, and automatic lesion quantification results stored in DICOM-SR format. The web-based system aims to be integrated in DICOM-compliant clinical and research environments to aid clinicians in patient treatments and disease tracking. This year, we have further developed the eFolder system to handle big data analysis and data mining in today's medical imaging field. The database has been updated to allow data mining and data look-up from DICOM-SR lesion analysis contents. Longitudinal studies are tracked, and any changes in lesion volumes and brain parenchyma volumes are calculated and shown on the webbased user interface as graphical representations. Longitudinal lesion characteristic changes are compared with patients' disease history, including treatments, symptom progressions, and any other changes in the disease profile. The image viewer is updated such that imaging studies can be viewed side-by-side to allow visual comparisons. We aim to use the web-based medical imaging informatics eFolder system to demonstrate big data analysis in medical imaging, and use the analysis results to predict MS disease trends and patterns in Hispanic and Caucasian populations in our pilot study. The discovery of disease patterns among the two ethnicities is a big data analysis result that will help lead to personalized patient care and treatment planning.

DOE Office of Scientific and Technical Information (OSTI.GOV)

North, Michael J.

SchemaOnRead provides tools for implementing schema-on-read including a single function call (e.g., schemaOnRead("filename")) that reads text (TXT), comma separated value (CSV), raster image (BMP, PNG, GIF, TIFF, and JPG), R data (RDS), HDF5, NetCDF, spreadsheet (XLS, XLSX, ODS, and DIF), Weka Attribute-Relation File Format (ARFF), Epi Info (REC), Pajek network (PAJ), R network (NET), Hypertext Markup Language (HTML), SPSS (SAV), Systat (SYS), and Stata (DTA) files. It also recursively reads folders (e.g., schemaOnRead("folder")), returning a nested list of the contained elements.

FOLDER: A numerical tool to simulate the development of structures in layered media

NASA Astrophysics Data System (ADS)

Adamuszek, Marta; Dabrowski, Marcin; Schmid, Daniel W.

2015-04-01

FOLDER is a numerical toolbox for modelling deformation in layered media during layer parallel shortening or extension in two dimensions. FOLDER builds on MILAMIN [1], a finite element method based mechanical solver, with a range of utilities included from the MUTILS package [2]. Numerical mesh is generated using the Triangle software [3]. The toolbox includes features that allow for: 1) designing complex structures such as multi-layer stacks, 2) accurately simulating large-strain deformation of linear and non-linear viscous materials, 3) post-processing of various physical fields such as velocity (total and perturbing), rate of deformation, finite strain, stress, deviatoric stress, pressure, apparent viscosity. FOLDER is designed to ensure maximum flexibility to configure model geometry, define material parameters, specify range of numerical parameters in simulations and choose the plotting options. FOLDER is an open source MATLAB application and comes with a user friendly graphical interface. The toolbox additionally comprises an educational application that illustrates various analytical solutions of growth rates calculated for the cases of folding and necking of a single layer with interfaces perturbed with a single sinusoidal waveform. We further derive two novel analytical expressions for the growth rate in the cases of folding and necking of a linear viscous layer embedded in a linear viscous medium of a finite thickness. We use FOLDER to test the accuracy of single-layer folding simulations using various 1) spatial and temporal resolutions, 2) time integration schemes, and 3) iterative algorithms for non-linear materials. The accuracy of the numerical results is quantified by: 1) comparing them to analytical solution, if available, or 2) running convergence tests. As a result, we provide a map of the most optimal choice of grid size, time step, and number of iterations to keep the results of the numerical simulations below a given error for a given time integration scheme. We also demonstrate that Euler and Leapfrog time integration schemes are not recommended for any practical use. Finally, the capabilities of the toolbox are illustrated based on two examples: 1) shortening of a synthetic multi-layer sequence and 2) extension of a folded quartz vein embedded in phyllite from Sprague Upper Reservoir (example discussed by Sherwin and Chapple [4]). The latter example demonstrates that FOLDER can be successfully used for reverse modelling and mechanical restoration. [1] Dabrowski, M., Krotkiewski, M., and Schmid, D. W., 2008, MILAMIN: MATLAB-based finite element method solver for large problems. Geochemistry Geophysics Geosystems, vol. 9. [2] Krotkiewski, M. and Dabrowski M., 2010 Parallel symmetric sparse matrix-vector product on scalar multi-core cpus. Parallel Computing, 36(4):181-198 [3] Shewchuk, J. R., 1996, Triangle: Engineering a 2D Quality Mesh Generator and Delaunay Triangulator, In: Applied Computational Geometry: Towards Geometric Engineering'' (Ming C. Lin and Dinesh Manocha, editors), Vol. 1148 of Lecture Notes in Computer Science, pp. 203-222, Springer-Verlag, Berlin [4] Sherwin, J.A., Chapple, W.M., 1968. Wavelengths of single layer folds - a Comparison between theory and Observation. American Journal of Science 266 (3), p. 167-179

NoSQL: collection document and cloud by using a dynamic web query form

NASA Astrophysics Data System (ADS)

Abdalla, Hemn B.; Lin, Jinzhao; Li, Guoquan

2015-07-01

Mongo-DB (from "humongous") is an open-source document database and the leading NoSQL database. A NoSQL (Not Only SQL, next generation databases, being non-relational, deal, open-source and horizontally scalable) presenting a mechanism for storage and retrieval of documents. Previously, we stored and retrieved the data using the SQL queries. Here, we use the MonogoDB that means we are not utilizing the MySQL and SQL queries. Directly importing the documents into our Drives, retrieving the documents on that drive by not applying the SQL queries, using the IO BufferReader and Writer, BufferReader for importing our type of document files to my folder (Drive). For retrieving the document files, the usage is BufferWriter from the particular folder (or) Drive. In this sense, providing the security for those storing files for what purpose means if we store the documents in our local folder means all or views that file and modified that file. So preventing that file, we are furnishing the security. The original document files will be changed to another format like in this paper; Binary format is used. Our documents will be converting to the binary format after that direct storing in one of our folder, that time the storage space will provide the private key for accessing that file. Wherever any user tries to discover the Document files means that file data are in the binary format, the document's file owner simply views that original format using that personal key from receive the secret key from the cloud.

Fast protein folding kinetics

PubMed Central

Gelman, Hannah; Gruebele, Martin

2014-01-01

Fast folding proteins have been a major focus of computational and experimental study because they are accessible to both techniques: they are small and fast enough to be reasonably simulated with current computational power, but have dynamics slow enough to be observed with specially developed experimental techniques. This coupled study of fast folding proteins has provided insight into the mechanisms which allow some proteins to find their native conformation well less than 1 ms and has uncovered examples of theoretically predicted phenomena such as downhill folding. The study of fast folders also informs our understanding of even “slow” folding processes: fast folders are small, relatively simple protein domains and the principles that govern their folding also govern the folding of more complex systems. This review summarizes the major theoretical and experimental techniques used to study fast folding proteins and provides an overview of the major findings of fast folding research. Finally, we examine the themes that have emerged from studying fast folders and briefly summarize their application to protein folding in general as well as some work that is left to do. PMID:24641816

Theoretical studies on the synthesis of SHE 290-302Og (Z=118) using 48Ca, 45Sc, 50Ti, 51V, 54Cr, 55Mn, 58Fe, 59Co and 64Ni induced reactions

NASA Astrophysics Data System (ADS)

Santhosh, K. P.; Safoora, V.

2018-05-01

Using the phenomenological model for production cross section (PMPC), the production cross sections for the synthesis of isotopes of superheavy element Og ( Z = 118) using the fusion reactions 48Ca+249-254Cf → 297-302Og, 45Sc+247,249Bk → 292,294Og, 50Ti + 242-248,250Cm → 292-298,300Og, 51V+241,243Am → 292,294Og, 54Cr + 238-242,244Pu → 292-296,298Og, 55Mn + 235-237Np → 290-292Og, 58Fe + 232-236, 238U → 290-294,296Og, 59Co + 231Pa → 290Og, and 64Ni + 228-230,232Cm → 292-294,296Og in xn (x=3,4,5) evaporation channel have been systematically studied at energies near and above the Coulomb barrier. We have predicted most suitable projectile-target combinations for the synthesis of isotopes 290-302Og among these reactions. Our calculated evaporation residue (ER) cross section values for the reaction 48Ca + 249Cf → 297Og is in excellent agreement with available experimental values. For the synthesis of Og, among all the reactions mentioned above, the 3n channel cross section (2458 fb) is larger for 48Ca + 251Cf → 299Og; 4n channel cross section (212 fb) is larger for 48Ca + 252Cf → 300Og and 5n channel cross section (34 fb) is larger for 48Ca + 253Cf → 301Og. The second largest 3n channel cross section (1143 fb) is obtained for the reaction, 50Ti + 245Cm → 295Og. Our studies will be useful for the future experiments to synthesize the isotopes of element Og which are not synthesized so far. We have also studied the effect of the use of mass values and shell correction of the Warsaw group which leads to a smaller ER cross section compared to the Moller group.

Population Size, Growth, and Environmental Justice Near Oil and Gas Wells in Colorado.

PubMed

McKenzie, Lisa M; Allshouse, William B; Burke, Troy; Blair, Benjamin D; Adgate, John L

2016-11-01

We evaluated population size and factors influencing environmental justice near oil and gas (O&G) wells. We mapped nearest O&G well to residential properties to evaluate population size, temporal relationships between housing and O&G development, and 2012 housing market value distributions in three major Colorado O&G basins. We reviewed land use, building, real estate, and state O&G regulations to evaluate distributive and participatory justice. We found that by 2012 at least 378,000 Coloradans lived within 1 mile of an active O&G well, and this population was growing at a faster rate than the overall population. In the Denver Julesburg and San Juan basins, which experienced substantial O&G development prior to 2000, we observed a larger proportion of lower value homes within 500 feet of an O&G well and that most O&G wells predated houses. In the Piceance Basin, which had not experienced substantial prior O&G development, we observed a larger proportion of high value homes within 500 feet of an O&G well and that most houses predated O&G wells. We observed economic, rural, participatory, and/or distributive injustices that could contribute to health risk vulnerabilities in populations near O&G wells. We encourage policy makers to consider measures to reduce these injustices.

Rickettsia Phylogenomics: Unwinding the Intricacies of Obligate Intracellular Life

PubMed Central

Gillespie, Joseph J.; Williams, Kelly; Shukla, Maulik; Snyder, Eric E.; Nordberg, Eric K.; Ceraul, Shane M.; Dharmanolla, Chitti; Rainey, Daphne; Soneja, Jeetendra; Shallom, Joshua M.; Vishnubhat, Nataraj Dongre; Wattam, Rebecca; Purkayastha, Anjan; Czar, Michael; Crasta, Oswald; Setubal, Joao C.; Azad, Abdu F.; Sobral, Bruno S.

2008-01-01

Background Completed genome sequences are rapidly increasing for Rickettsia, obligate intracellular α-proteobacteria responsible for various human diseases, including epidemic typhus and Rocky Mountain spotted fever. In light of phylogeny, the establishment of orthologous groups (OGs) of open reading frames (ORFs) will distinguish the core rickettsial genes and other group specific genes (class 1 OGs or C1OGs) from those distributed indiscriminately throughout the rickettsial tree (class 2 OG or C2OGs). Methodology/Principal Findings We present 1823 representative (no gene duplications) and 259 non-representative (at least one gene duplication) rickettsial OGs. While the highly reductive (∼1.2 MB) Rickettsia genomes range in predicted ORFs from 872 to 1512, a core of 752 OGs was identified, depicting the essential Rickettsia genes. Unsurprisingly, this core lacks many metabolic genes, reflecting the dependence on host resources for growth and survival. Additionally, we bolster our recent reclassification of Rickettsia by identifying OGs that define the AG (ancestral group), TG (typhus group), TRG (transitional group), and SFG (spotted fever group) rickettsiae. OGs for insect-associated species, tick-associated species and species that harbor plasmids were also predicted. Through superimposition of all OGs over robust phylogeny estimation, we discern between C1OGs and C2OGs, the latter depicting genes either decaying from the conserved C1OGs or acquired laterally. Finally, scrutiny of non-representative OGs revealed high levels of split genes versus gene duplications, with both phenomena confounding gene orthology assignment. Interestingly, non-representative OGs, as well as OGs comprised of several gene families typically involved in microbial pathogenicity and/or the acquisition of virulence factors, fall predominantly within C2OG distributions. Conclusion/Significance Collectively, we determined the relative conservation and distribution of 14354 predicted ORFs from 10 rickettsial genomes across robust phylogeny estimation. The data, available at PATRIC (PathoSystems Resource Integration Center), provide novel information for unwinding the intricacies associated with Rickettsia pathogenesis, expanding the range of potential diagnostic, vaccine and therapeutic targets. PMID:19194535

A novel smart supramolecular organic gelator exhibiting dual-channel responsive sensing behaviours towards fluoride ion via gel-gel states.

PubMed

Mehdi, Hassan; Pang, Hongchang; Gong, Weitao; Dhinakaran, Manivannan Kalavathi; Wajahat, Ali; Kuang, Xiaojun; Ning, Guiling

2016-07-07

A novel smart supramolecular organic gelator G-16 containing anion and metal-coordination ability has been designed and synthesized. It shows excellent and robust gelation capability as a strong blue fluorescent supramolecular organic gel OG in DMF. Addition of Zn(2+) produced Zn(2+)-coordinated supramolecular metallogel OG-Zn. Organic gel OG and organometallic gel OG-Zn exhibited efficient and different sensing behaviors towards fluoride ion due to the variation in self-assembling nature. Supramolecular metallogel OG-Zn displayed specific selectivity for fluoride ion and formed OG-Zn-F with dramatic color change from blue to blue green in solution and gel to gel states. Furthermore after directly addition of fluoride into OG produced fluoride containing organic gel OG-F with drastically modulation in color from blue to greenish yellow fluorescence via strong aggregation-induced emission (AIE) property. A number of experiments were conducted such as FTIR, (1)H NMR, and UV/Vis spectroscopies, XRD, SEM and rheology. These results revealed that the driving forces involved in self-assembly of OG, OG-Zn, OG-Zn-F and OG-F were hydrogen bonding, metal coordination, π-π interactions, and van der Waal forces. In contrast to the most anion responsive gels, particularly fluoride ion responsive gels showed gel-sol state transition on stimulation by anions, the gel state of OG and OG-Zn did not show any gel-to-sol transition during the whole F(-) response process.

[Investigation on source and dissemination way of knowledge on schistosomiasis prevention and control in population in Jingjiang City after transmission-interrupted].

PubMed

Wang, Ji-sheng; Chen, Jian-feng; Liu, Ya-hong; Song, Liang-liang

2016-02-01

To understand the source of knowledge on schistosomiasis prevention and control and the acceptable degree on different propagation patterns of population in Jingjiang City after schistosomiasis transmission-interrupted, so as to provide the evidence for the production of suitable materials for health education. The permanent residents, floating population as well as the primary school students in Grade 5 and 6 in riverside regions in Jingjiang City were selected as the investigation objects, the information propagation condition and the knowledge source, and the expected propagation patterns were investigated by questionnaires. The popularizing rates on the television, computer and mobile phone of the villagers were 99.81%, 84.16% and 87.78%, respectively. Both the two investigated schools had the independent TV network, broadcast and multimedia, and all the computer classroom could connected to Internet. The main sources on schistosomiasis control of permanent residents and floating population were folders and the exhibition board (62.0% and 40.5% respectively), the substantial material (42.0% and 33.5% respectively) and TV (40.5% and 36.0% respectively), while those of the students were video CD (100%), substantial material (99.5%) and folders and the exhibition boards (84.2%). The propagation ways with high acceptable degrees among the residents and floating population were substantial material, folders and the exhibition boards and short messages by mobile phone, while those among the students were video CD, substantial material, folders and the exhibition boards. The material on health education should be targeted to the demands of the different populations and their condition of information propagation, in addition, the Internet material should be developed and the communicational channels should be broaden.

Factors detracting students from applying for an obstetrics and gynecology residency.

PubMed

Gariti, Dominique L; Zollinger, Terrell W; Look, Katherine Y

2005-07-01

This study compares perception about the characteristics of obstetrics-gynecology (OG) of medical students who choose to pursue a residency in OG and those students who choose to enter another specialty. Fourth-year medical students were asked to complete a survey addressing their perceptions about OG. Responses were compared of (1) those entering OG to those entering other specialties, (2) those entering OG to those who seriously considered entering OG but chose another discipline, and (3) males to females. Chi-square tests were used for the comparisons. Of the 267 eligible students, 137 (51.1%) completed the survey. Clerkship satisfaction was rated as high by 88.9% of students choosing OG vs 10.2% (P<.0005) of those who chose another discipline. The emerging predominance of female providers detracted 38.5% of males vs 10.2% of females (P<.0005). Student perception of an OG clerkship may detract them from pursuing OG as a career.

Comperative studies with Culex pipiens egg rafts. Immunogenetic, electrophoretic and enzymatic analysis of unfertilized, compatible and incompatible fertilized eggs.

PubMed

Schumann, W

1974-01-01

By applying immunologic, electrophoretic and enzymatic methods, extracts of different raft types of Culex pipiens were analysed. Rafts of the crosses Pa x Pa and Ha x Ha contained four common antigens, while unfertilized rafts of Pa and Ha (no antisera were prepared against them) and rafts of the crosses Og x Og, Og x Pa, and Pa x Og shared three common antigens with the remaining raft extracts. Disk-electrophoresis of raft extracts in acrylamide gel resulted in different electropherograms. Ten protein bands were common to all these raft types. The unfertilized rafts of Pa and Ha yielded three more protein bands, the crosses Pa x Ha and Ha x Pa one more, the crosses Og x Og and Pa x Og three more, and Og x Pa two more. Many enzymes were demonstrated in the raft extracts after they were separated in acrylamide gel and incubated with the corresponding substrate solutions. All the raft types possessed one enzyme type for glutaminate-, lactate-, glucose-6-phosphate-dehydrogenase and catalase. Malate-dehydrogenase and leucine aminopeptidase occurred in each raft type as two isoenzymes. Alkaline phosphatase was observed as a single enzyme, but was lacking in rafts of the crosses Pa X Pa and Ha X Ha. While rafts of the crosses Og x Og and Og x Pa possessed two acid phosphatases, three could be demonstrated for the remaining raft types. Up to eight esterases appeared; rafts of the crosses Og x Og and Og x Pa possessed seven such activities. The results obtained by the Ouchterlony test, disk-electrophoresis and the histochemical enzyme tests are discussed in context and checked according to the phenomenon of incompatibility.

An Image Archive With The ACR/NEMA Message Formats

NASA Astrophysics Data System (ADS)

Seshadri, Sridhar B.; Khalsa, Satjeet; Arenson, Ronald L.; Brikman, Inna; Davey, Michael J.

1988-06-01

An image archive has been designed to manage and store radiologic images received from within the main Hospital and a from a suburban orthopedic clinic. Images are stored on both magnetic as well as optical media. Prior comparison examinations are combined with the current examination to generate a 'viewing folder' that is sent to the display station for primary diagnosis. An 'archive-manager' controls the database managment, periodic optical disk backup and 'viewing-folder' generation. Images are converted into the ACR/NEMA message format before being written to the optical disk. The software design of the 'archive-manager' and its associated modules is presented. Enhancements to the system are discussed.

Topographic and hydrographic GIS dataset for the Afghanistan Geological Survey and U.S. Geological Survey 2010 Minerals Project

USGS Publications Warehouse

Chirico, P.G.; Moran, T.W.

2011-01-01

This dataset contains a collection of 24 folders, each representing a specific U.S. Geological Survey area of interest (AOI; fig. 1), as well as datasets for AOI subsets. Each folder includes the extent, contours, Digital Elevation Model (DEM), and hydrography of the corresponding AOI, which are organized into feature vector and raster datasets. The dataset comprises a geographic information system (GIS), which is available upon request from the USGS Afghanistan programs Web site (http://afghanistan.cr.usgs.gov/minerals.php), and the maps of the 24 areas of interest of the USGS AOIs.

Characteristic Features of Kynurenine Aminotransferase Allosterically Regulated by (Alpha)-Ketoglutarate in Cooperation with Kynurenine

PubMed Central

Okada, Ken; Angkawidjaja, Clement; Koga, Yuichi; Takano, Kazufumi; Kanaya, Shigenori

2012-01-01

Kynurenine aminotransferase from Pyrococcus horikoshii OT3 (PhKAT), which is a homodimeric protein, catalyzes the conversion of kynurenine (KYN) to kynurenic acid (KYNA). We analyzed the transaminase reaction mechanisms of this protein with pyridoxal-5′-phosphate (PLP), KYN and α-ketoglutaric acid (2OG) or oxaloacetic acid (OXA). 2OG significantly inhibited KAT activities in kinetic analyses, suggesting that a KYNA biosynthesis is allosterically regulated by 2OG. Its inhibitions evidently were unlocked by KYN. 2OG and KYN functioned as an inhibitor and activator in response to changes in the concentrations of KYN and 2OG, respectively. The affinities of one subunit for PLP or 2OG were different from that of the other subunit, as confirmed by spectrophotometry and isothermal titration calorimetry, suggesting that the difference of affinities between subunits might play a role in regulations of the KAT reaction. Moreover, we identified two active and allosteric sites in the crystal structure of PhKAT-2OG complexes. The crystal structure of PhKAT in complex with four 2OGs demonstrates that two 2OGs in allosteric sites are effector molecules which inhibit the KYNA productions. Thus, the combined data lead to the conclusion that PhKAT probably is regulated by allosteric control machineries, with 2OG as the allosteric inhibitor. PMID:22792273

Understanding Outdoor Gyms in Public Open Spaces: A Systematic Review and Integrative Synthesis of Qualitative and Quantitative Evidence

PubMed Central

Lee, Janet Lok Chun; Lo, Temmy Lee Ting

2018-01-01

(1) Background: An outdoor gym (OG) is environmental infrastructure built in a public open space to promote structured physical activity. The provision of OGs is increasingly seen as an important strategy to realize public health agendas promoting habitual physical activity. A systematic review was conducted to synthesize characteristics of OG and OG users’ experiences and perceptions in different cultural contexts; (2) Methods: Online searches of multidisciplinary databases were conducted in health, sport and recreation, and urban planning disciplines. Characteristics of OGs were synthesized by integrating evidence from quantitative, qualitative, and mix-methods studies. The experiences and perceptions of OG users from both qualitative data and survey responses were synthesized through framework analysis; (3) Results: Nine studies met the inclusion criteria (three quantitative studies, four mixed-methods studies, and two pure qualitative studies). None were excluded on the basis of quality. OGs mainly serve adult and older adult population groups. Their size, design, and instructional support vary across studies. The inclusion of functional types of equipment did not have a unified standard. Regarding experiences and perceptions of OGs, five major themes emerged: “health”, “social connectedness”, “affordable”, “support”, and “design and promotion”; (4) Conclusions: The OG characteristics synthesis guides the direction in further studies regarding exploration of design parameters. The qualitative and quantitative synthesis revealed that health was a central theme of users’ experiences. OGs are also spaces where community-dwellers can find social connectedness while participating in structured physical activity at no cost. Findings from this review create knowledge support for OG as environmental infrastructure for further research and facilitate the understanding of users’ experiences and perceptions of OGs in different cultural contexts. PMID:29587402

Using GTO-Velo to Facilitate Communication and Sharing of Simulation Results in Support of the Geothermal Technologies Office Code Comparison Study

DOE Office of Scientific and Technical Information (OSTI.GOV)

White, Signe K.; Purohit, Sumit; Boyd, Lauren W.

The Geothermal Technologies Office Code Comparison Study (GTO-CCS) aims to support the DOE Geothermal Technologies Office in organizing and executing a model comparison activity. This project is directed at testing, diagnosing differences, and demonstrating modeling capabilities of a worldwide collection of numerical simulators for evaluating geothermal technologies. Teams of researchers are collaborating in this code comparison effort, and it is important to be able to share results in a forum where technical discussions can easily take place without requiring teams to travel to a common location. Pacific Northwest National Laboratory has developed an open-source, flexible framework called Velo that providesmore » a knowledge management infrastructure and tools to support modeling and simulation for a variety of types of projects in a number of scientific domains. GTO-Velo is a customized version of the Velo Framework that is being used as the collaborative tool in support of the GTO-CCS project. Velo is designed around a novel integration of a collaborative Web-based environment and a scalable enterprise Content Management System (CMS). The underlying framework provides a flexible and unstructured data storage system that allows for easy upload of files that can be in any format. Data files are organized in hierarchical folders and each folder and each file has a corresponding wiki page for metadata. The user interacts with Velo through a web browser based wiki technology, providing the benefit of familiarity and ease of use. High-level folders have been defined in GTO-Velo for the benchmark problem descriptions, descriptions of simulator/code capabilities, a project notebook, and folders for participating teams. Each team has a subfolder with write access limited only to the team members, where they can upload their simulation results. The GTO-CCS participants are charged with defining the benchmark problems for the study, and as each GTO-CCS Benchmark problem is defined, the problem creator can provide a description using a template on the metadata page corresponding to the benchmark problem folder. Project documents, references and videos of the weekly online meetings are shared via GTO-Velo. A results comparison tool allows users to plot their uploaded simulation results on the fly, along with those of other teams, to facilitate weekly discussions of the benchmark problem results being generated by the teams. GTO-Velo is an invaluable tool providing the project coordinators and team members with a framework for collaboration among geographically dispersed organizations.« less

Systemic Induction of the Defensin and Phytoalexin Pisatin Pathways in Pea (Pisum sativum) against Aphanomyces euteiches by Acetylated and Nonacetylated Oligogalacturonides.

PubMed

Selim, Sameh; Sanssené, Jean; Rossard, Stéphanie; Courtois, Josiane

2017-06-19

Oligogalacturonides (OGs) are known for their powerful ability to stimulate the plant immune system but little is known about their mode of action in pea ( Pisum sativum ). In the present study, we investigated the elicitor activity of two fractions of OGs, with polymerization degrees (DPs) of 2-25, in pea against Aphanomyces euteiches . One fraction was nonacetylated (OGs - Ac) whereas the second one was 30% acetylated (OGs + Ac). OGs were applied by injecting the upper two rachises of the plants at three- and/or four-weeks-old. Five-week-old roots were inoculated with 10⁵ zoospores of A. euteiches . The root infection level was determined at 7, 10 and 14 days after inoculation using the quantitative real-time polymerase chain reaction (qPCR). Results showed significant root infection reductions namely 58, 45 and 48% in the plants treated with 80 µg OGs + Ac and 59, 56 and 65% with 200 µg of OGs - Ac. Gene expression results showed the upregulation of genes involved in the antifungal defensins, lignans and the phytoalexin pisatin pathways and a priming effect in the basal defense, SA and ROS gene markers as a response to OGs. The reduction of the efficient dose in OGs + Ac is suggesting that acetylation is necessary for some specific responses. Our work provides the first evidence for the potential of OGs in the defense induction in pea against Aphanomyces root rot.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jeon, En Hee; Pak, Jung Hun; Kim, Mi Jin

Highlights: Black-Right-Pointing-Pointer We isolated a novel E2 ubiquitin-conjugating enzyme from leaves of wild rice plants. Black-Right-Pointing-Pointer The OgUBC1 was highly expressed in leaves treated with SA and UV-B radiation. Black-Right-Pointing-Pointer The recombinant OgUBC1 has an enzymatic activity of E2 in vitro. Black-Right-Pointing-Pointer The OgUBC1 could protect disruption of plant cells by UV-B radiation. Black-Right-Pointing-Pointer OgUBC1 confers disease resistance and UV-B tolerance in transgenic Arabidopsis plants. -- Abstract: A previously unidentified gene encoding ubiquitin-conjugating enzyme was isolated from leaves of wild rice plant treated with wounding and microbe-associated molecular patterns. The OgUBC1 gene was composed of 148 amino acids and containedmore » a typical active site and 21 ubiquitin thioester intermediate interaction residues and 4 E3 interaction residues. Both exogenous application of salicylic acid and UV-B irradiation triggered expression of OgUBC1 in leaves of wild rice. Recombinant OgUBC1 proteins bound to ubiquitins in vitro, proposing that the protein might act as E2 enzyme in planta. Heterologous expression of the OgUBC1 in Arabidopsis thaliana protected plants from cellular damage caused by an excess of UV-B radiation. A stable expression of chalcone synthase gene was detected in leaves of OgUBC1-expressing Arabidopsis, resulting in producing higher amounts of anthocyanin than those in wild-type Col-0 plants. Additionally, both pathogenesis-related gene1 and 5 were transcribed in the transgenic Arabidopsis in the absence of pathogen infection. The OgUBC1-expressing plants were resistant to the infection of Botrytis cinerea. Taken together, we suggested that the OgUBC1 is involved in ubiquitination process important for cellular response against biotic and abiotic stresses in plants.« less

Energy balance-dependent regulation of ovine glucose 6-phosphate dehydrogenase protein isoform expression.

PubMed

Triantaphyllopoulos, Kostas A; Laliotis, George P; Bizelis, Iosif A

2014-01-01

G6PDH is the rate-limiting enzyme of the pentose phosphate pathway and one of the principal source of NADPH, a major cellular reductant. Importantly, in ruminant's metabolism the aforementioned NADPH provided, is utilized for de novo fatty acid synthesis. Previous work of cloning the ovine (Ovis aries) og6pdh gene has revealed the presence of two cDNA transcripts (og6pda and og6pdb), og6pdb being a product of alternative splicing not similar to any other previously reported.(1) In the current study the effect of energy balance in the ovine G6PDH protein expression was investigated, shedding light on the biochemical features and potential physiological role of the oG6PDB isoform. Changes in energy balance leads to protein expression changes in both transcripts, to the opposite direction and not in a proportional way. Negative energy balance was not in favor of the presence of any particular isoform, while both protein expression levels were not significantly different (P > 0.05). In contrast, at the transition point from negative to positive and on the positive energy balance, there is a significant increase of oG6PDA compared with oG6PDB protein expression (P < 0.001). Both oG6PDH protein isoforms changed significantly toward the positive energy balance. oG6PDA is escalating, while oG6PDB is falling, under the same stimulus (positive energy balance alteration). This change is also positively associated with increasing levels in enzyme activity, 4 weeks post-weaning in ewes' adipose tissue. Furthermore, regression analysis clearly demonstrated the linear correlation of both proteins in response to the WPW, while energy balance, enzyme activity, and oG6PDA relative protein expression follow the same escalating trend; in contrast, oG6PDB relative protein expression falls in time, similar to both transcripts accumulation pattern, as reported previously.(2.)

Green synthesized nickel nanoparticles for targeted detection and killing of S. typhimurium.

PubMed

Jeyaraj Pandian, Chitra; Palanivel, Rameshthangam; Balasundaram, Usha

2017-09-01

Simple and sensitive colorimetric immunosensor based on peroxidase mimetic activity and photothermal effect of nickel oxide nanoparticle (NiOGs) has been developed to detect and kill food borne pathogen Salmonella typhimurium. NiOGs showed superior peroxidase mimetic activity for oxidation of peroxidase substrate 3, 3', 5, 5'-tetramethylbenzidine (TMB). Oxidation of TMB by NiOGs followed Michaelis-Menten kinetics with K m and V max values of 0.25mM and 2.64×10 -8 M/s respectively. NiOGs was coated with citric acid (CA-NiOGs) followed by conjugation with antibody (anti-S. typhimurium) (Ab-CA-NiOGs) that effectively captured S. typhimurium. Colorimetric detection of S. typhimurium by Ab-CA-NiOGs showed a linear relationship between pathogen concentration (1×10 1 to 1×10 6 cfu/mL) and color signal (652nm) with limit of detection (LOD) of 10cfu/mL. The proposed method showed no cross reactivity against other pathogens. Recovery of S. typhimurium in milk and juice samples was found to be 95 to 100% and 92 to 99% respectively. NiOGs exposed to laser irradiation showed dose dependent increase in temperature and singlet oxygen within 5min. Bacteria bound to Ab-CA-NiOGs after laser irradiation, induced membrane damage and reduced bacterial viability to 6%. The bifunctional peroxidase-mimetic activity and photothermal effect of NiOGs can be exploited in selective sensing and killing of target pathogens respectively in food products. Copyright © 2017 Elsevier B.V. All rights reserved.

Unnatural substrates reveal the importance of 8-oxoguanine for in vivo mismatch repair by MutY

PubMed Central

Livingston, Alison L.; O’Shea, Valerie L.; Kim, Taewoo; Kool, Eric T.; David, Sheila S.

2009-01-01

Escherchia coli MutY plays an important role in preventing mutations associated with the oxidative lesion 7,8-dihydro-8-oxo-2′-deoxyguanosine (OG) in DNA by excising adenines from OG:A mismatches as the first step of base excision repair. To determine the importance of specific steps in the base pair recognition and base removal process of MutY, we have evaluated the effects of modifications of the OG:A substrate on the kinetics of base removal, mismatch affinity and repair to G:C in an Escherchia coli-based assay. Surprisingly, adenine modification was tolerated in the cellular assay, while modification of OG results in minimal cellular repair. High affinity for the mismatch and efficient base removal require the presence of OG. Taken together, these results suggest that the presence of OG is a critical feature for MutY to locate OG:A mismatches and select the appropriate adenines for excision to initiate repair in vivo prior to replication. PMID:18026095

Olumacostat glasaretil, a novel topical sebum inhibitor, in the treatment of acne vulgaris: A phase IIa, multicenter, randomized, vehicle-controlled study.

PubMed

Bissonnette, Robert; Poulin, Yves; Drew, Janice; Hofland, Hans; Tan, Jerry

2017-01-01

Olumacostat glasaretil (OG) inhibits acetyl-coenzyme A carboxylase, the enzyme responsible for the first, rate-limiting step in de novo fatty acid synthesis. OG inhibited in vitro human sebocyte lipid production and reduced in vivo sebaceous gland size in hamster ears. Safety and efficacy of OG 7.5% gel were evaluated in patients with moderate to severe facial acne vulgaris. Patients were randomized (1:1) to twice-daily application of OG or vehicle for 12 weeks. Efficacy was measured through changes in lesion counts and improvement in acne severity scores. A total of 108 patients received OG (n = 53) or vehicle (n = 55); these groups had mean baseline counts of 29.7 and 28.6 inflammatory and 40.9 and 38.8 noninflammatory lesions, respectively. At week 12, OG treatment showed greater reductions from baseline in inflammatory lesions (-63.9% vs -45.9%; P = .0006) and noninflammatory lesions (-48.1% vs -28.8%; P = .0025), and more patients with greater than or equal to 2-grade improvement in investigator global assessment score (24.5% vs 7.3%; P = .0070) than vehicle. Application-site adverse events (typically mild or moderate intensity) were more common with OG. Larger trials are needed to optimize OG dosing and confirm the current results. OG was well tolerated and showed evidence of efficacy, suggesting further development is warranted. Copyright © 2016. Published by Elsevier Inc.

The Medical Home

MedlinePlus

... in files on a computer or within an electronic medical record (EMR) , or in paper folders. When ... 2014 More on this topic for: Parents Teens Electronic Health Records Talking to Your Child's Doctor How ...

Earth Observation

NASA Image and Video Library

2014-06-27

Earth Observation taken during a day pass by the Expedition 40 crew aboard the International Space Station (ISS). Part of Space Station Remote Manipulator System (SSRMS) is visible. Folder lists this as: the Middle East, Israel.

Methylation effect on chalcone synthase gene expression determines anthocyanin pigmentation in floral tissues of two Oncidium orchid cultivars.

PubMed

Liu, Xiao-Jing; Chuang, Yao-Nung; Chiou, Chung-Yi; Chin, Dan-Chu; Shen, Fu-Quan; Yeh, Kai-Wun

2012-08-01

The anthocyanin-biosynthetic pathway was studied in flowers of Oncidium Gower Ramsey with yellow floral color and mosaic red anthocyanin in lip crests, sepals and petals, and compared with the anthocyanin biosynthesis in flowers of Oncidium Honey Dollp, a natural somatoclone derived from tissue culture of Gower Ramsey, with a yellow perianth without red anthocyanins in floral tissues. HPLC analysis revealed that the red anthocyanin in lip crests of the Gower Ramsey cultivar comprised peonidin-3-O-glucoside, delphinidin-3-O-glucoside and cyanidin-3-O-glucoside, whereas Honey Dollp was devoid of anthocyanin compounds. Among the five anthocyanin-biosynthetic genes, OgCHS was actively expressed in lip crests of Gower Ramsey flowers, but no transcripts of OgCHS were detected in Honey Dollp floral tissues. Transient expression of OgCHS by bombardment confirmed that recovery of the OgCHS gene expression completed the anthocyanin pathway and produced anthocyanin compounds in lip crests of Honey Dollp flowers. Transcription factor genes regulating anthocyanin biosynthesis showed no distinctive differences in the expression level of OgMYB1, OgbHLH and OgWD40 between the two cultivars. A methylation assay revealed that the promoter of OgCHS was not methylated in Gower Ramsey, while a positive methylation effect was present in the upstream promoter region of OgCHS in Honey Dollp. Overall, our results suggest that the failure of anthocyanin accumulation in Honey Dollp floral tissues may be attributed to inactivation of the OgCHS gene resulting from the epigenetic methylation of 5'-upstream promoter region.

Comparing top-down and bottom-up estimates of methane emissions across multiple U.S. oil and gas basins provides insights into national O&G emissions, mitigation strategies, and research priorities

NASA Astrophysics Data System (ADS)

Lyon, D. R.; Alvarez, R.; Zavala Araiza, D.; Hamburg, S.

2017-12-01

We develop a county-level inventory of U.S. anthropogenic methane emissions by integrating multiple data sources including the Drillinginfo oil and gas (O&G) production database, Environmental Protection Agency (EPA) Greenhouse Gas Reporting Program, a previously published gridded EPA Greenhouse Gas Inventory (Maasakkers et al 2016), and recent measurements studies of O&G pneumatic devices, equipment leaks, abandoned wells, and midstream facilities. Our bottom-up estimates of total and O&G methane emissions are consistently lower than top-down, aerial mass balance estimates in ten O&G production areas. We evaluate several hypotheses for the top-down/bottom-up discrepancy including potential bias of the aerial mass balance method, temporal mismatch of top-down and bottom-up emission estimates, and source attribution errors. In most basins, the top-down/bottom-up gap cannot be explained fully without additional O&G emissions from sources not included in traditional inventories, such as super-emitters caused by malfunctions or abnormal process conditions. Top-down/bottom-up differences across multiple basins are analyzed to estimate the magnitude of these additional emissions and constrain total methane emissions from the U.S. O&G supply chain. We discuss the implications for mitigating O&G methane emissions and suggest research priorities for increasing the accuracy of future emission inventories.

Development of a see-through hollow cathode discharge lamp for (Li/Ne) optogalvanic studies

NASA Astrophysics Data System (ADS)

Saini, V. K.; Kumar, P.; Sarangpani, K. K.; Dixit, S. K.; Nakhe, S. V.

2017-09-01

Development of a demountable and see-through hollow cathode (HC) discharge lamp suitable for optogalvanic (OG) spectroscopy is described. The design of the HC lamp is simple, compact, and inexpensive. Lithium, investigated rarely by the OG method, is selected for cathode material as its isotopes are important for nuclear industry. The HC lamp is characterized electrically and optically for discharge oscillations free OG effect. Strong OG signals of lithium as well as neon (as buffer gas) are produced precisely upon copper vapor laser pumped tunable dye laser irradiation. The HC lamp is capable of generating a clean OG resonance spectrum in the available dye laser wavelength scanning range (627.5-676 nm) obtained with 4-(Dicyanomethylene)-2-methyl-6-(4-dimethylaminostyryl)-4H-pyran dye. About 28 resonant OG lines are explicitly observed. Majority of them have been identified using j-l coupling scheme and assigned to the well-known neon transitions. One line that corresponds to wavelength near about 670.80 nm is assigned to lithium and resolved for its fine (2S1/2 → 2P1/2, 3/2) transitions. These OG transitions allow 0.33 cm-1 accuracy and can be used to supplement the OG transition data available from other sources to calibrate the wavelength of a scanning dye laser with precision at atomic levels.

Development of a see-through hollow cathode discharge lamp for (Li/Ne) optogalvanic studies.

PubMed

Saini, V K; Kumar, P; Sarangpani, K K; Dixit, S K; Nakhe, S V

2017-09-01

Development of a demountable and see-through hollow cathode (HC) discharge lamp suitable for optogalvanic (OG) spectroscopy is described. The design of the HC lamp is simple, compact, and inexpensive. Lithium, investigated rarely by the OG method, is selected for cathode material as its isotopes are important for nuclear industry. The HC lamp is characterized electrically and optically for discharge oscillations free OG effect. Strong OG signals of lithium as well as neon (as buffer gas) are produced precisely upon copper vapor laser pumped tunable dye laser irradiation. The HC lamp is capable of generating a clean OG resonance spectrum in the available dye laser wavelength scanning range (627.5-676 nm) obtained with 4-(Dicyanomethylene)-2-methyl-6-(4-dimethylaminostyryl)-4H-pyran dye. About 28 resonant OG lines are explicitly observed. Majority of them have been identified using j-l coupling scheme and assigned to the well-known neon transitions. One line that corresponds to wavelength near about 670.80 nm is assigned to lithium and resolved for its fine ( 2 S 1/2 → 2 P 1/2, 3/2 ) transitions. These OG transitions allow 0.33 cm -1 accuracy and can be used to supplement the OG transition data available from other sources to calibrate the wavelength of a scanning dye laser with precision at atomic levels.

Earth Observation

NASA Image and Video Library

2014-09-01

Earth Observation taken during a night pass by the Expedition 40 crew aboard the International Space Station (ISS). Folder lists this as: New Zealand Aurora night pass. On crewmember's Flickr page - Look straight down into an aurora.

Earth Observation

NASA Image and Video Library

2014-06-12

Earth Observation taken during a day pass by the Expedition 40 crew aboard the International Space Station (ISS). Folder lists this as: Moon, Japan, Kamchatka with a wild cloud. Part of a solar array is also visible.

5 CFR 293.311 - Availability of information.

Code of Federal Regulations, 2013 CFR

2013-01-01

... information from both the OPF and employee performance file system folders, their automated equivalent records, and from other personnel record files that constitute an agency record within the meaning of the FOIA...

5 CFR 293.311 - Availability of information.

Code of Federal Regulations, 2012 CFR

2012-01-01

... information from both the OPF and employee performance file system folders, their automated equivalent records, and from other personnel record files that constitute an agency record within the meaning of the FOIA...

5 CFR 293.311 - Availability of information.

Code of Federal Regulations, 2014 CFR

2014-01-01

... information from both the OPF and employee performance file system folders, their automated equivalent records, and from other personnel record files that constitute an agency record within the meaning of the FOIA...

5 CFR 293.311 - Availability of information.

Code of Federal Regulations, 2010 CFR

2010-01-01

... information from both the OPF and employee performance file system folders, their automated equivalent records, and from other personnel record files that constitute an agency record within the meaning of the FOIA...

5 CFR 293.311 - Availability of information.

Code of Federal Regulations, 2011 CFR

2011-01-01

... information from both the OPF and employee performance file system folders, their automated equivalent records, and from other personnel record files that constitute an agency record within the meaning of the FOIA...

Unmatched speed perceptions between overground and treadmill manual wheelchair propulsion in long-term manual wheelchair users.

PubMed

Chénier, Félix; Champagne, Audrey; Desroches, Guillaume; Gagnon, Dany H

2018-03-01

Manual wheelchair (MWC) propulsion is increasingly assessed on a motorized treadmill (TM), which is often considered more ecologically valid than stationary rollers. However, no clear consensus on the similarities between overground (OG) and TM propulsion has yet been reached. Furthermore, no study has investigated the participants' perceptions of propelling a MWC on a TM compared to OG. The present study aims to assess the perception of speed when propelling on a TM vs OG, and to relate this perception to measured spatiotemporal variables, kinetics and work. In this repeated-measures study, the propulsion's spatiotemporal variables, kinetics, and work of nineteen experienced wheelchair users with a spinal cord injury were compared between three conditions: 1) OG at a self-selected speed, 2) on a TM at a self-selected speed perceived as being similar to the OG speed (TM perceived ), and 3) on a TM at the same speed as OG (TM matched ). Each variable was compared between conditions using an analysis of variance for repeated measures. All participants selected a lower speed for TM perceived than OG, with a difference of -0.6 m/s (-44%). This adaptation may be due to a combination of two factors: 1) the absence of speed information, and 2) the feeling of urgency to grab the wheels during the recovery phase. The power output, work per cycle, and work per minute were also much lower on TM perceived than OG. However, in contrast to other work on MWC propulsion on a TM, the kinetic variables assessed were all similar between the OG and TM matched conditions. Training on a TM should be performed at a speed that matches the OG speed and not at a self-selected speed on the TM, which would reduce the power output and work and therefore reduce the efficiency of the training. Copyright © 2018 Elsevier B.V. All rights reserved.

Stationary Combustion Turbines: National Emission Standards for Hazardous Air Pollutants (NESHAP)

EPA Pesticide Factsheets

Learn about the NESHAP for stationary combustion turbines by reading the rule history, the rule summary, additional resources, docket folder documents, the economic impact analysis, fact sheet and more

HEP Computing

Science.gov Websites

Service Request Password Help New Users Back to HEP Computing Mail-Migration Procedure on Linux Mail -Migration Procedure on Windows How to Migrate a Folder to GMail using Pine U.S. Department of Energy The

The Viking Portable.

ERIC Educational Resources Information Center

Cohen, Alan S.

1984-01-01

Describes a final exercise that gives composition students a better sense of how they have grown as writers during the semester. Students review, edit, and make conclusions on their "selected works," preparing a manuscript-like folder. (HTH)

An audit on the reporting of critical results in a tertiary institute.

PubMed

Rensburg, Megan A; Nutt, Louise; Zemlin, Annalise E; Erasmus, Rajiv T

2009-03-01

Critical result reporting is a requirement for accreditation by accreditation bodies worldwide. Accurate, prompt communication of results to the clinician by the laboratory is of extreme importance. Repeating of the critical result by the recipient has been used as a means to improve the accuracy of notification. Our objective was to assess the accuracy of notification of critical chemical pathology laboratory results telephoned out to clinicians/clinical areas. We hypothesize that read-back of telephoned critical laboratory results by the recipient may improve the accuracy of the notification. This was a prospective study, where all critical results telephoned by chemical pathologists and registrars at Tygerberg Hospital were monitored for one month. The recipient was required to repeat the result (patient name, folder number and test results). Any error, as well as the designation of the recipient was logged. Of 472 outgoing telephone calls, 51 errors were detected (error rate 10.8%). Most errors were made when recording the folder number (64.7%), with incorrect patient name being the lowest (5.9%). Calls to the clinicians had the highest error rate (20%), most of them being the omission of recording folder numbers. Our audit highlights the potential errors during the post-analytical phase of laboratory testing. The importance of critical result reporting is still poorly recognized in South Africa. Implementation of a uniform accredited practice for communication of critical results can reduce error and improve patient safety.

The use of the osmole gap as a screening test for the presence of exogenous substances.

PubMed

Purssell, Roy A; Lynd, Larry D; Koga, Yoshikata

2004-01-01

The rapid and accurate diagnosis of toxic alcohol poisoning due to methanol (methyl alcohol) [MeOH] and ethylene glycol (EG), is paramount in preventing serious adverse outcomes. The quantitative measurement of specific serum levels of these substances using gas chromatography is expensive, time consuming and generally only available at major tertiary-care facilities. Therefore, because these toxic substances are osmotically active and the measurement of serum osmolality is easily performed and more readily available, the presence of an osmole gap (OG) has been adopted as an alternative screening test. By definition, the OG is the difference between the measured serum osmolality determined using the freezing point depression (Osm(m)) and the calculated serum molarity (Mc), which is estimated from the known and readily measurable osmotically active substances in the serum, in particular sodium, urea, glucose, and potassium and ethanol (alcohol). Thus, the OG=Osm(m)-Mc, and an OG above a specific threshold (the threshold of positivity) suggests the presence of unmeasured osmotically active substances, which could be indicative of a toxic exposure. The objectives of this study were to review the principles of evaluating screening tests, the theory behind the OG as a screening test and the literature upon which the adoption of the OG as a screening test has been based. This review revealed that there have been numerous equations derived and proposed for the estimation of the Mc, with the objective of developing empirical evidence of the best equation for the determination of the OG and ultimately the utility of OG as a screening test. However, the methods and statistical analysis employed have generally been inconsistent with recommended guidelines for screening test evaluation and although many equations have been derived, they have not been appropriately validated. Specific evidence of the clinical utility of the OG requires that a threshold of positivity be definitively established, and the sensitivity and specificity of the OG in patients exposed to either EG or MeOH be measured. However, the majority of studies to date have only evaluated the relationship between the Osm(m) (mmol/kg H2O) and the Mc (mmol/L) in patients that have not been exposed to either MeOH or EG. While some studies have evaluated the relationship between the OG and serum ethanol concentration, these findings cannot be extrapolated to the use of the OG to screen for toxic alcohol exposure. This review shows that there has not been an appropriately designed empirical evaluation of the diagnostic utility of the OG and that its clinical utility remains hypothetical, having been theoretically extrapolated from the non-poisoned population.

Earth Observation

NASA Image and Video Library

2014-06-12

Earth Observation taken during a day pass by the Expedition 40 crew aboard the International Space Station (ISS). Folder lists this as: Moon, Japan, Kamchatka with a wild cloud. Part of the U.S. Lab and PMM are also visible.

A Real-Life Basis for Reports in Business and Technical Writing.

ERIC Educational Resources Information Center

Stephenson, William

1987-01-01

For students who have difficulty finding material for writing formal business and technical reports, suggests keeping a file folder of clippings about new products and services taken from a leading newspaper.(NH)

76 FR 45783 - Privacy Act of 1974; System of Records

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-01

... complying with mandatory background checks, i.e., Brady Handgun Violence Prevention Act (18 U.S.C. 922) and... folders and on electronic media. Retrievability: By name or other identifier of individual. Safeguards...

Earth Observation

NASA Image and Video Library

2014-05-31

Earth Observation taken during a day pass by the Expedition 40 crew aboard the International Space Station (ISS). Folder lists this as: CEO - Arena de Sao Paolo. View used for Twitter message: Cloudy skies over São Paulo Brazil

Environmental and Human Health Impacts of Spreading Oil and Gas Wastewater on Roads.

PubMed

Tasker, T L; Burgos, W D; Piotrowski, P; Castillo-Meza, L; Blewett, T A; Ganow, K B; Stallworth, A; Delompré, P L M; Goss, G G; Fowler, L B; Vanden Heuvel, J P; Dorman, F; Warner, N R

2018-06-19

Thirteen states in the United States allow the spreading of O&G wastewaters on roads for deicing or dust suppression. In this study, the potential environmental and human health impacts of this practice are evaluated. Analyses of O&G wastewaters spread on roads in the northeastern, U.S. show that these wastewaters have salt, radioactivity, and organic contaminant concentrations often many times above drinking water standards. Bioassays also indicated that these wastewaters contain organic micropollutants that affected signaling pathways consistent with xenobiotic metabolism and caused toxicity to aquatic organisms like Daphnia magna. The potential toxicity of these wastewaters is a concern as lab experiments demonstrated that nearly all of the metals from these wastewaters leach from roads after rain events, likely reaching ground and surface water. Release of a known carcinogen (e.g., radium) from roads treated with O&G wastewaters has been largely ignored. In Pennsylvania from 2008 to 2014, spreading O&G wastewater on roads released over 4 times more radium to the environment (320 millicuries) than O&G wastewater treatment facilities and 200 times more radium than spill events. Currently, state-by-state regulations do not require radium analyses prior to treating roads with O&G wastewaters. Methods for reducing the potential impacts of spreading O&G wastewaters on roads are discussed.

Methanol extract of Ocimum gratissimum protects murine peritoneal macrophages from nicotine toxicity by decreasing free radical generation, lipid and protein damage and enhances antioxidant protection

PubMed Central

Mahapatra, Santanu Kar; Chakraborty, Subhankari Prasad; Das, Subhasis

2009-01-01

In the present study, methanol extract of Ocimum gratissimum Linn (ME-Og) was tested against nicotine-induced murine peritoneal macrophage in vitro. Phytochemical analysis of ME-Og shown high amount of flavonoid and phenolic compound present in it. The cytotoxic effect of ME-Og was studied in murine peritoneal macrophages at different concentrations (0.1 to 100 µg/ml) using the 3-(4, 5-dimethylthiazol-2-yl)-2, 5 diphenyltetrazolium bromide (MTT) method. To establish the protective role of ME-Og against nicotine toxicity, peritoneal macrophages from mice were treated with nicotine (10 mM), nicotine + ME-Og (1 to 25 µg/ml) for 12 h in culture media. The significantly (p < 0.05) increased super oxide anion generation, reduced nicotinamide adenine dinucleotide phosphate (NADPH) oxidase activity, myeloperoxidase (MPO) activity, lipid peroxidation, protein carbonyls, oxidized glutathione levels were observed in nicotine-treated group as compared to control group; those were significantly (p < 0.05) reduced in ME-Og supplemented groups in concentration dependent manner. More over, significantly (p < 0.05) reduced antioxidant status due to nicotine exposure was effectively ameliorated by ME-Og supplementation in murine peritoneal macrophages. Among the different concentration of ME-Og, maximum protective effect was observed by 25 µg/ml, which does not produce significant cell cytotoxicity in murine peritoneal macrophages. These findings suggest the potential use and beneficial role of O. gratissimum as a modulator of nicotine-induced free radical generation, lipid-protein damage and antioxidant status in important immune cell, peritoneal macrophages. PMID:20716908

Outcome of Laparoscopic Adrenalectomy in Obese Patients.

PubMed

Paun, Diana; Petris, Rodica; Ganescu, Roxana; Paun, Sorin; Vartic, Mihaela; Beuran, Mircea

2015-09-01

To compare early morbidity of obese and nonobese patients with minimally invasive adrenalectomies. Retrospective study of a prospectively maintained database, between June 2003 - December 2012, in a universitary affiliated tertiary hospital. Selection criteria: Minimally invasive adrenalectomy. Obese patients were defined as BMI over 30 kg/m2. From 205 patient with laparoscopic adrenalectomies we counted 30 obese patients (OG), 25 of them female and only 5 men with a median age of 54,20 years versus 47,94 years for nonobese group (NOG) (p=0.008). In OG were 15 right sided tumor, 11 on the left side and 4 bilateral all treated with transperitoneal antero-lateral approach. Median operating time was 92.20 minutes for OG versus 91.13 minutes for NOG (p=0.924). In OG, 5 patients had previous abdominal surgeries and we counted 4 conversion to open surgery, 2 postoperative complications (6.6%) and no mortality. All OG patients have diverse comorbidities, 50% of them more then 3. Median specimen size was 5.92 cm for OG versus 4.85 cm for NOG (p=0.057). The histology of OG was: adenoma 11 cases, hiperplasia 13 cases and pheochromocytoma 6. In NOG we had: postoperative hospital stay was 6.57 days in OG versus 4.11 days in NOG (p=0.009). Although obese patients had a higher rate for early morbidities, the minimally invasive approach has particular benefits for them. Although postoperative hospital stay was significantly longer, we believe that advantages of minimal invasive surgery for obese patients remains valid even in a BMI over 30.

1987 Paragon Awards.

ERIC Educational Resources Information Center

Golden, Sandra

1987-01-01

Describes the annual Paragon Award winners, representing 76 successful community college marketing efforts in the areas of overall promotion; best catalog, schedule, annual report, newsletter, news story, viewbook, brochure, poster, folder, postcard, outdoor advertising, print advertisement, radio advertisement, video promotion, photographs, media…

Personal Information Management for Nurses Returning to School.

PubMed

Bowman, Katherine

2015-12-01

Registered nurses with a diploma or an associate's degree are encouraged to return to school to earn a Bachelor of Science in Nursing degree. Until they return to school, many RNs have little need to regularly write, store, and retrieve work-related papers, but they are expected to complete the majority of assignments using a computer when in the student role. Personal information management (PIM) is a system of organizing and managing electronic information that will reduce computer clutter, while enhancing time use, task management, and productivity. This article introduces three PIM strategies for managing school work. Nesting is the creation of a system of folders to form a hierarchy for storing and retrieving electronic documents. Each folder, subfolder, and document must be given a meaningful unique name. Numbering is used to create different versions of the same paper, while preserving the original document. Copyright 2015, SLACK Incorporated.

User modeling techniques as support in the clinical decision-making process.

PubMed

Ferri, F

1995-01-01

This paper describes research work on the design and creation of a medical folder management system capable of establishing co-operative dialogue with users who have access to the information contained therein. The research work has addressed the problem of integrating into the system knowledge about the medical domain and that about users, both necessary to activate co-operative dialogue. The CADMIO [2] prototype has been developed since the study was made. The last version of the CADMIO system stores information about users for the use in recognizing and interpreting their behavior, providing help, and in acquiring and returning further information. Depending on this information the system retrieves and shows the data of the medical folder in an intelligent way by highlighting links between data. It simplifies and increases the speed of the interaction by focusing on the data useful to the decisional activity of the physician.

Efect of an educative action on relatives' knowledge about childhood burns at home.

PubMed

Gimeniz-Paschoal, Sandra Regina; Pereira, Débora Morais; Nascimento, Edinalva Neves

2009-01-01

This article aimed to evaluate the effect of an educative action on the knowledge of children's relatives about burns at home. Participants were 40 relatives of children under four years of age, equally divided between an intervention and control group. An initial interview was held, the educative action involved a folder about burns and, after one week, another interview took place. The answers were compared using Fisher's statistical test. In the first interview, 60 answers on risk situations were registered in the control group and 62 in the intervention group; in the second, the results increased to 61 and 80, respectively. In the first interview, 90% of the control group and 80% of the intervention group expressed the belief that childhood burns can be avoided; in the second, this indication decreased to 84% and increased to 100%, respectively. This study showed the importance of the advisory folder on burns at home.

Octyl gallate reduces ATP levels and Ki67 expression leading HepG2 cells to cell cycle arrest and mitochondria-mediated apoptosis.

PubMed

Lima, Kelly Goulart; Krause, Gabriele Catyana; da Silva, Elisa Feller Gonçalves; Xavier, Léder Leal; Martins, Léo Anderson Meira; Alice, Laura Manzoli; da Luz, Luiza Bueno; Gassen, Rodrigo Benedetti; Filippi-Chiela, Eduardo Cremonese; Haute, Gabriela Viegas; Garcia, Maria Claudia Rosa; Funchal, Giselle Afonso; Pedrazza, Leonardo; Reghelin, Camille Kirinus; de Oliveira, Jarbas Rodrigues

2018-04-01

Octyl gallate (OG) is an antioxidant that has shown anti-tumor, anti-diabetic and anti-amyloidogenic activities. Mitochondria play an important role in hepatocellular carcinoma, mainly by maintaining accelerated cellular proliferation through the production of ATP. Thus, the mitochondria may be a target for antitumor therapies. Here, we investigated the effects of OG in the hepatocarcinoma cell line (HepG2) and the mechanisms involved. We report, for the first time, that treatment with OG for 24h inhibited HepG2 cell growth by decreasing mitochondrial activity and mass, which led to the reduction of ATP levels. This reduction in the energy supply triggered a decrease in Ki67 protein expression, leading cells to cycle arrest. In addition, treatment with two doses of OG for 48h induced loss of mitochondrial functionality, mitochondrial swelling and apoptosis. Finally, we report that HepG2 cells had no resistance to treatment after multiple doses. Collectively, our findings indicate that metabolic dysregulation and Ki67 protein reduction are key events in the initial anti-proliferative action of OG, whereas mitochondrial swelling and apoptosis induction are involved in the action mechanism of OG after prolonged exposure. This suggests that OG targets mitochondria, thus representing a candidate for further research on therapies for hepatocarcinoma. Copyright © 2017 Elsevier Ltd. All rights reserved.

Ocimum gratissimum retards breast cancer growth and progression and is a natural inhibitor of matrix metalloproteases

PubMed Central

Nangia-Makker, Pratima; Raz, Tirza; Tait, Larry; Shekhar, Malathy P.V.; Li, Hong; Balan, Vitaly; Makker, Hemanckur; Fridman, Rafael; Maddipati, Krishnarao; Raz, Avraham

2013-01-01

Ocimum genus (a.k.a holy basil or tulsi) is a dietary herb used for its multiple beneficial pharmacologic properties including anti-cancer activity. Here we show that crude extract of Ocimum gratissimum (OG) and its hydrophobic and hydrophilic fractions (HB and HL) differentially inhibit breast cancer cell chemotaxis and chemoinvasion in vitro and retard tumor growth and temporal progression of MCF10ADCIS.com xenografts, a model of human breast comedo-ductal carcinoma in situ (comedo-DCIS). OG-induced inhibition of tumor growth was associated with decreases in basement membrane disintegration, angiogenesis and MMP-2 and MMP-9 activities as confirmed by in situ gelatin zymography and cleavage of galectin-3. There was also decrease in MMP-2 and MMP-9 activities in the conditioned media of OG-treated MCF10AT1 and MCF10AT1-EIII8 premalignant human breast cancer cells as compared with control. The MMP-2 and MMP-9 inhibitory activities of OG were verified in vitro using gelatin, a synthetic fluorogenic peptide and recombinant galectin-3 as MMP substrates. Mice fed on OG-supplemented drinking water showed no adverse effects compared with control. These data suggest that OG is non-toxic and that the anti-cancer therapeutic activity of OG may in part be contributed by its MMP inhibitory activity. PMID:23380593

2-Oxoglutarate levels control adenosine nucleotide binding by Herbaspirillum seropedicae PII proteins.

PubMed

Oliveira, Marco A S; Gerhardt, Edileusa C M; Huergo, Luciano F; Souza, Emanuel M; Pedrosa, Fábio O; Chubatsu, Leda S

2015-12-01

Nitrogen metabolism in Proteobacteria is controlled by the Ntr system, in which PII proteins play a pivotal role, controlling the activity of target proteins in response to the metabolic state of the cell. Characterization of the binding of molecular effectors to these proteins can provide information about their regulation. Here, the binding of ATP, ADP and 2-oxoglutarate (2-OG) to the Herbaspirillum seropedicae PII proteins, GlnB and GlnK, was characterized using isothermal titration calorimetry. Results show that these proteins can bind three molecules of ATP, ADP and 2-OG with homotropic negative cooperativity, and 2-OG binding stabilizes the binding of ATP. Results also show that the affinity of uridylylated forms of GlnB and GlnK for nucleotides is significantly lower than that of the nonuridylylated proteins. Furthermore, fluctuations in the intracellular concentration of 2-OG in response to nitrogen availability are shown. Results suggest that under nitrogen-limiting conditions, PII proteins tend to bind ATP and 2-OG. By contrast, after an ammonium shock, a decrease in the 2-OG concentration is observed causing a decrease in the affinity of PII proteins for ATP. This phenomenon may facilitate the exchange of ATP for ADP on the ligand-binding pocket of PII proteins, thus it is likely that under low ammonium, low 2-OG levels would favor the ADP-bound state. © 2015 FEBS.

Medical abortions performed by specialists in private practice.

PubMed

Pay, Aase Serine Devold; Aabø, Runa Sigrid; Økland, Inger; Janbu, Torunn; Iversen, Ole-Erik; Løkeland, Mette

2018-05-29

I Norge utføres abort kun i offentlige sykehus. I 2010 besluttet Helse- og omsorgsdepartementet å iverksette et toårig prøveprosjekt som ga avtalespesialister i fødselshjelp og kvinnesykdommer adgang til å tilby medikamentell abort før utgangen av 9. svangerskapsuke. Prøveprosjektet ble igangsatt 1.3.2015 og varte til 31.3.2017. I denne artikkelen presenterer vi de første erfaringene, herunder hvordan behandlingstilbudet ble mottatt av kvinnene. Gravide med en svangerskapsvarighet < 63 dager ultrasonografisk vurdert, som oppsøkte avtalespesialist for medikamentell abort, ble fortløpende inkludert i prosjektet (n = 476). Kvinnene inntok 200 mg mifepriston peroralt på legekontoret, 36-48 timer senere satte de selv 800 µg misoprostol vaginalt hjemme. Informasjon ble innhentet ved spørreskjema på den første konsultasjonen, under aborten og ved etterkontrollen 2-4 uker etter aborten. Under aborten rapporterte 66 % (296/450) moderat eller sterk smerte og 79 % (358/451) moderat eller sterk blødning. De fleste opplevde det som trygt å være hjemme. 96 % (390/406) ville valgt medikamentell abort hos avtalespesialist ved en eventuell senere abort, og 97 % (392/405) ville anbefalt behandlingstilbudet til andre i samme situasjon. Kvinnene i studien opplevde abortbehandling hos avtalespesialist som trygt. Tilbudet gir større valgfrihet til gravide som ønsker abort, og pasientene er tilfredse.

Operational Group Sandy technical progress report

USGS Publications Warehouse

,

2013-01-01

This report documents results from the March 2013 deployment of the OGS. It includes background information on Hurricane Sandy and the federal response; the OGS methodology; scenarios for Hurricane Sandy’s impact on coastal communities and urban ecosystems; potential interventions to improve regional resilience to future major storms; a discussion of scenario results; and lessons learned about the OGS process.

Wind Tunnel Test of NASA’s Most Powerful Rocket (360° Animation)

NASA Image and Video Library

2018-01-08

What are wind tunnels? And how do they help researchers design and test next-generation aircraft and spacecraft? This interactive 360° animation takes you inside the Unitary Plan Wind Tunnel at NASA’s Ames Research Center in Silicon Valley. The facility is one of seven wind tunnels located at Ames for exploring the complex physics of flight. The video features a four percent scale model of NASA’s most powerful rocket, the Space Launch System, or SLS. Two SLS models--one silver and one pink--appear in the video. The latter is coated with a special paint to track surface pressure readings during testing. Once built, the SLS rocket will be capable of sending astronauts on bold new missions into deep space. How to watch 360 content in VR? YouTube and Google Cardboard 1. Open YouTube on your mobile device and select the video. 2. Click the Google Cardboard icon on the bottom right. 3. Insert the mobile device into the Google Cardboard device. 4. Watch through the headset. Samsung Gear VR 1. Download the 360 mp4 video file. 2. Create a folder in the root directory of your device or SD Card called “MilkVR” 3. Put the video file in that folder. 4. Open the Samsung VR application from the Oculus App 5. Insert the phone into the Gear VR 6. Put on the VR headset. 7. Navigate to the section called “Sideloaded” 8. Select the video from “Storage 1”. 9. The optimal viewing format is 360 x 360. Change the format by selecting thing format icon on the bottom right. PlayStation VR 1. Download the 360 mp4 video file from NASA.gov. 2. Create a folder on a USB drive, formatted in FAT32 or exFat. 3. Copy the video file into that folder. 4. Insert the USB drive in the PlayStation 4 5. Connect the PlayStation VR headset to the PlayStation 4 and turn on the power. 6. Put on the VR headset. 7. Open the PlayStation Media Player (updated to v2.50 or higher). 8. Be sure the Media Player is set to “VR Mode” by holding the “Option” button to enable it. 9. Open the video file and watch the video.

The opposite roles of agdA and glaA on citric acid production in Aspergillus niger.

PubMed

Wang, Lu; Cao, Zhanglei; Hou, Li; Yin, Liuhua; Wang, Dawei; Gao, Qiang; Wu, Zhenqiang; Wang, Depei

2016-07-01

Citric acid is produced by an industrial-scale process of fermentation using Aspergillus niger as a microbial cell factory. However, citric acid production was hindered by the non-fermentable isomaltose and insufficient saccharification ability in A. niger when liquefied corn starch was used as a raw material. In this study, A. niger TNA 101ΔagdA was constructed by deletion of the α-glucosidase-encoding agdA gene in A. niger CGMCC 10142 genome using Agrobacterium tumefaciens-mediated transformation. The transformants A. niger OG 1, OG 17, and OG 31 then underwent overexpression of glucoamylase in A. niger TNA 101ΔagdA. The results showed that the α-glucosidase activity of TNA 101ΔagdA was decreased by 62.5 % compared with CGMCC 10142, and isomaltose was almost undetectable in the fermentation broth. The glucoamylase activity of the transformants OG 1 and OG 17 increased by 34.5 and 16.89 % compared with that of TNA 101ΔagdA, respectively. In addition, for the recombinants TNA 101ΔagdA, OG 1 and OG 17, there were no apparent defects in the growth development. Consequently, in comparison with CGMCC 10142, TNA 101ΔagdA and OG 1 decreased the residual reducing sugar by 52.95 and 88.24 %, respectively, and correspondingly increased citric acid production at the end of fermentation by 8.68 and 16.87 %. Citric acid production was further improved by decreasing the non-fermentable residual sugar and increasing utilization rate of corn starch material in A. niger. Besides, the successive saccharification and citric acid fermentation processes were successfully integrated into one step.

Oxygen Generator System Mars In-Situ Propellant Production Precursor Flight

NASA Technical Reports Server (NTRS)

Sridhar, K. R.; Gottmann, M.; Baird, R. S.

1999-01-01

The 2001 Lander to Mars will carry the first ever ISRU payload to Mars. This payload, the Mars In-situ Propellant production Precursor (MIP), will demonstrate a variety of technologies that will be required for future ISRU Mars indigenous material processing plant designs. One of those technologies is that of extracting oxygen from the predominantly carbon dioxide atmosphere of Mars, a prerequisite for future sample return and human missions to Mars. The Oxygen Generator Subsystem (OGS) portion of the MIP will demonstrate this and is the focus of this paper. The primary objective of the OGS is to demonstrate the production of oxygen from Mars atmospheric gases. Secondary objectives are to measure the performance and reliability of oxygen generation hardware in actual mission environments over an extended time. Major constraints on the OGS design came from several sources. The Lander provides power to the system from solar power that is harnessed by photovoltaic arrays. This limited OGS to daytime only operations (six to eight hours) and a maximum power of 15W. The reliance on solar power necessitated thermal cycling of the OGS between Mars ambient and OGS operating temperatures. The Lander also limited the total mass of the MIP payload to 7.5 kg with a correspondingly small volume, and the OGS was one of six experiments in the MIP. Mass and volume were to be minimized. Another constraint was cost. Mission funding, as always, was tight. Cost was to be minimized. In short the OGS design had to be low power (<15 Watts), low mass (1 kg), low volume, low cost, and be capable of cyclical operations for an extended stay on Mars. After extensive research, a zirconia based solid oxide electrolyzer design was selected.

Oxygen Generator System Mars In-Situ Propellant Production Precursor Flight

NASA Technical Reports Server (NTRS)

Sridhar, K. R.; Gottmann, M.; Baird, R. S.

1999-01-01

The 2001 Lander to Mars will carry the first ever In situ Resource Utilization (ISRU) payload to Mars. This payload, the Mars In-situ Propellant production Precursor (MIP), will demonstrate a variety of technologies that will be required for future ISRU Mars indigenous material processing plant designs. One of those technologies is that of extracting oxygen from the predominantly carbon dioxide atmosphere of Mars, a prerequisite for future sample return and human missions to Mars. The Oxygen Generator Subsystem (OGS) portion of the MIP will demonstrate this and is the focus of this paper. The primary objective of the OGS is to demonstrate the production of oxygen from Mars atmospheric gases. Secondary objectives are to measure the performance and reliability of oxygen generation hardware in actual mission environments over an extended time. Major constraints on the OGS design came from several sources. The Lander provides power to the system from solar power that is harnessed by photovoltaic arrays. This limited OGS to daytime only operations (six to eight hours) and a maximum power of 15W. The reliance on solar power necessitated thermal cycling of the OGS between Mars ambient and OGS operating temperatures. The Lander also limited the total mass of the MIP payload to 7.5 kg with a correspondingly small volume, and the OGS was one of six experiments in the MIP Mass and volume were to be minimized. Another constraint was cost. Mission funding, as always, was tight. Cost was to be minimized. In short the OGS design had to be low power (<15 Watts), low mass (1 kg), low volume, low cost, and be capable of cyclical operations for an extended stay on Mars. After extensive research, a zirconia based solid oxide electrolyzer design was selected.

Distribution of the P2X2 receptor and chemical coding in ileal enteric neurons of obese male mice (ob/ob)

PubMed Central

Mizuno, Márcia Sanae; Crisma, Amanda Rabello; Borelli, Primavera; Schäfer, Bárbara Tavares; Silveira, Mariana Póvoa; Castelucci, Patricia

2014-01-01

AIM: To investigate the colocalization, density and profile of neuronal areas of enteric neurons in the ileum of male obese mice. METHODS: The small intestinal samples of male mice in an obese group (OG) (C57BL/6J ob/ob) and a control group (CG) (+/+) were used. The tissues were analyzed using a double immunostaining technique for immunoreactivity (ir) of the P2X2 receptor, nitric oxide synthase (NOS), choline acetyl transferase (ChAT) and calretinin (Calr). Also, we investigated the density and profile of neuronal areas of the NOS-, ChAT- and Calr-ir neurons in the myenteric plexus. Myenteric neurons were labeled using an NADH-diaphorase histochemical staining method. RESULTS: The analysis demonstrated that the P2X2 receptor was expressed in the cytoplasm and in the nuclear and cytoplasmic membranes only in the CG. Neuronal density values (neuron/cm2) decreased 31% (CG: 6579 ± 837; OG: 4556 ± 407) and 16.5% (CG: 7796 ± 528; OG: 6513 ± 610) in the NOS-ir and calretinin-ir neurons in the OG, respectively (P < 0.05). Density of ChAT-ir (CG: 6200 ± 310; OG: 8125 ± 749) neurons significantly increased 31% in the OG (P < 0.05). Neuron size studies demonstrated that NOS, ChAT, and Calr-ir neurons did not differ significantly between the CG and OG groups. The examination of NADH-diaphorase-positive myenteric neurons revealed an overall similarity between the OG and CG. CONCLUSION: Obesity may exert its effects by promoting a decrease in P2X2 receptor expression and modifications in the density of the NOS-ir, ChAT-ir and CalR-ir myenteric neurons. PMID:25320527

Foot-Ground Reaction Force During Resistance Exercise in Parabolic Flight

NASA Technical Reports Server (NTRS)

Lee, Stuart M. C.; Cobb, Kendall; Loehr, James A.; Nguyen, Daniel; Schneider, Suzanne M.

2003-01-01

An interim Resistance Exercise Device (iRED) was designed to provide resistive exercise as a countermeasure to space flight-induced loss of muscle strength and endurance as well as decreased bone mineral density. The purpose of this project was to compare foot-ground reaction force during iRED exercise in normal gravity (l-g) versus micro gravity (O-g) achieved during parabolic flight. METHODS: Four subjects performed three exercises using the iRED (squat, heel raise, and deadlift) during I-g and O-g at a moderate intensity (60% of maximum strength during deadlift exercise). Foot-ground reaction force was measured in three axes (x,y,z) using a force plate, and the magnitude of the resultant force vector was calculated (r = X 2 + y2 + Z2 ). Range of motion (ROM) was measured using a linear encoder. Peak force (PkF) and total work (TW) were calculated using a customized computer program. Paired t-tests were used to test if significant differences (p.::::0.05) were observed between I-g and O-g exercise. RESULTS: PkF and TW measured in the resultant axis were significantly less in O-g for each of the exercises tested. During O-g, PkF was 42-46% and TW was 33- 37% of that measured during I-g. ROM and average time to complete each repetition were not different from I-g to O-g. CONCLUSIONS: When performing exercises in which body mass is a portion of the resistance during I-g, PkF and TW measured during resistive exercise were reduced approximately 60-70% during O-g. Thus, a resistive exercise device during O-g will be required to provided higher resistances to induce a similar training stimulus to that on Earth.

Detection of induced seismicity due to oil and gas extraction in the northern Gulf of Mexico, USA

NASA Astrophysics Data System (ADS)

Fadugba, Oluwaseun Idowu

Drilling operations and extraction of oil and gas (O&G) may lead to subsurface slumping or compression of sediments due to reduced vertical principal stress which may lead to small earthquakes at the drilling site. O&G extraction is common in the northern Gulf of Mexico (NGM) and only thirty-five earthquakes of magnitudes between 2.3 and 6.0 have been recorded in the area from 1974 to the present. The purpose of this research is to detect more earthquakes using stacks of seismic data from the Transportable USArray (TA) from 2011 to 2013, and determine the spatiotemporal relationship between the detected earthquakes and O&G extraction. Five new small offshore earthquakes, that may be associated with the offshore O&G production, have been detected in the data. Spatial correlation of the epicenters with offshore drilling sites shows that the earthquakes may be due to the O&G extraction.

Earth Observations taken by the Expedition 39 Crew

NASA Image and Video Library

2014-04-10

Earth observation taken by the Expedition 39 crew aboard the ISS. A portion of the docked Soyuz TMA-11M spacecraft is in view. Image was released by astronaut on Instagram and downlinked in folder: Personal photos and the Maldive islands.

75 FR 74019 - Privacy Act of 1974; System of Records

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-30

... storage media. Retrievability: Information is retrieved by individual's name, Social Security Number (SSN... ``Records include individual's name, Social Security Number (SSN); employee identification number....'' * * * * * Storage: Delete entry and replace with ``Paper records in file folders and electronic storage media...

IMPACT OF DEFICIENT NUTRITION IN BONE MASS AFTER BARIATRIC SURGERY.

PubMed

Costa, Tatiana Munhoz da Rocha Lemos; Paganoto, Mariana; Radominski, Rosana Bento; Borba, Victoria Zeghbi Cochenski

2016-03-01

Essential nutrients are considered for the prevention of the bone loss that occurs after bariatric surgery. Evaluate nutrients involved in bone metabolism, and relate to serum concentrations of calcium, vitamin D, and parathyroid hormone, and the use of supplements and sun exposure on the bone mass of patients who had undergone gastric bypass surgery. An observational study, with patients who had undergone the surgery 12 or more months previously, operated group (OG), compared to a control group (CG). Were included 56 in OG and 27 in the CG. The mean age was 36.4±8.5 years. The individuals in the OG, compared to CG, consumed inadequate amounts of protein and daily calcium. The OG had a higher prevalence of low sun exposure, lower levels of 25OH Vitamin D (21.3±10.9 vs. 32.1±11.8 ng/dl), and increased serum levels of parathyroid hormone (68.1±32.9 vs. 39.9±11.9 pg/ml, p<0.001). Secondary hyperparathyroidism was present only in the OG (41.7%). The mean lumbar spine bone mineral density was lower in the OG. Four individuals from the OG had low bone mineral density for chronological age, and no one from the CG. The dietary components that affect bone mass in patients undergoing bariatric surgery were inadequate. The supplementation was insufficient and the sun exposure was low. These changes were accompanied by secondary hyperparathyroidism and a high prevalence of low bone mass in lumbar spine in these subjects.

Extensive Copy Number Variations in Admixed Indian Population of African Ancestry: Potential Involvement in Adaptation

PubMed Central

Dash, Debasis; Mukerji, Mitali

2014-01-01

Admixture mapping has been enormously resourceful in identifying genetic variations linked to phenotypes, adaptation, and diseases. In this study through analysis of copy number variable regions (CNVRs), we report extensive restructuring in the genomes of the recently admixed African-Indian population (OG-W-IP) that inhabits a highly saline environment in Western India. The study included subjects from OG-W-IP (OG), five different Indian and three HapMap populations that were genotyped using Affymetrix version 6.0 arrays. Copy number variations (CNVs) detected using Birdsuite were used to define CNVRs. Population structure with respect to CNVRs was delineated using random forest approach. OG genomes have a surprising excess of CNVs in comparison to other studied populations. Individual ancestry proportions computed using STRUCTURE also reveals a unique genetic component in OGs. Population structure analysis with CNV genotypes indicates OG to be distant from both the African and Indian ancestral populations. Interestingly, it shows genetic proximity with respect to CNVs to only one Indian population IE-W-LP4, which also happens to reside in the same geographical region. We also observe a significant enrichment of molecular processes related to ion binding and receptor activity in genes encompassing OG-specific CNVRs. Our results suggest that retention of CNVRs from ancestral natives and de novo acquisition of CNVRs could accelerate the process of adaptation especially in an extreme environment. Additionally, this population would be enormously useful for dissecting genes and delineating the involvement of CNVs in salt adaptation. PMID:25398783

Effects of feeding an immunomodulatory supplement to heat-stressed or actively cooled cows during late gestation on postnatal immunity, health, and growth of calves.

PubMed

Skibiel, Amy L; Fabris, Thiago F; Corrá, Fabiana N; Torres, Yazielis M; McLean, Derek J; Chapman, James D; Kirk, David J; Dahl, Geoffrey E; Laporta, Jimena

2017-09-01

Heat stress during late gestation negatively affects the physiology, health, and productivity of dairy cows as well as the calves developing in utero. Providing cows with active cooling devices, such as fans and soakers, and supplementing cows with an immunomodulating feed additive, OmniGen-AF (OG; Phibro Animal Health Corporation), improves immune function and milk yield of cows. It is unknown if maternal supplementation of OG combined with active cooling during late gestation might benefit the developing calf as well. Herein we evaluated markers of innate immune function, including immune cell counts, acute phase proteins, and neutrophil function, of calves born to multiparous dams in a 2 × 2 factorial design. Dams were supplemented with OG or a bentonite control (NO) beginning at 60 d before dry off and exposed to heat stress with cooling (CL) or without active cooling (HT) during the dry period (∼46 d). At birth, calves were separated from their dams and fed 6.6 L of their dams' colostrum in 2 meals. Calf body weight and rectal temperature were recorded, and blood samples were collected at birth (before colostrum feeding) and at 10, 28, and 49 d of age. Calves born to either CL dams or OG dams were heavier at birth than calves born to HT or NO dams, respectively. Concentrations of serum amyloid A were higher in the blood of calves born to OG dams relative to NO and for HT calves relative to CL calves. In addition, calves born to cooled OG dams had greater concentrations of plasma haptoglobin than calves born to cooled control dams. Neutrophil function at 10 d of age was enhanced in calves born to cooled OG dams and lymphocyte counts were higher in calves born to OG dams. Together these results suggest that adding OG to maternal feed in combination with active cooling of cows during late gestation is effective in mitigating the negative effects of in utero heat stress on postnatal calf growth and immune competence. Copyright © 2017 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

Elderly patients with colorectal cancer: treatment modalities and survival in France. National data from the ThInDiT cohort study.

PubMed

Doat, S; Thiébaut, A; Samson, S; Ricordeau, P; Guillemot, D; Mitry, E

2014-05-01

Few data exist on how elderly patients with colorectal cancer (CRC) are actually treated in real-life practice. Based on a national cohort, we analysed routine treatment modalities of the elderly who were diagnosed with CRC in France in 2009. The characteristics of patients and tumours and the cancer treatments received during the first year of all national incident cases of CRC diagnosed between 1st April and 31st December 2009, were compared between a 'younger group' (YG), under 75 years of age (N = 18,410 patients), and an 'older group' (OG), aged 75 and over (N = 13,255 patients). In the OG with metastases at baseline, we analysed two-year overall survival (OS) according to the treatment received (e.g. chemotherapy, surgery) and well-known prognostic factors. Among patients with localised CRC (N = 25,353), surgery was equally performed in both groups in more than 80% of the cases (p=0.52); time to surgery was shorter in the OG (8 versus 23 days) because there was more emergency surgery for occlusion among the OG. Adjuvant chemotherapy was performed in 15% of the OG (versus 29% in the YG) and consisted of 5-fluorouracil (5FU) monotherapy in more than 50% of OG patients. Among patients with metastatic CRC (N = 6,312), palliative chemotherapy was given to 48% of the OG versus 85% of the YG. Chemotherapy regimens included 30% monotherapy with 5FU, 30% oxaliplatin combination and 20% bevacizumab combination in the OG; compared to 10%, 34% and 35%, respectively, in the YG. The median OS for the OG was 8.4 months (versus 22.3 months in the YG) and 17.1 months among elderly patients who received chemotherapy. CRC is more frequently complicated at diagnosis among elderly patients. Adjuvant and palliative chemotherapy is less frequently prescribed among elderly patients. This could be explained by the fact that unfit elderly patients do not deserve chemotherapy, but certainly also reflect the fact that some fit elderly patients are undertreated. Copyright © 2014 Elsevier Ltd. All rights reserved.

2008 Lead (Pb) National Ambient Air Quality Standards (NAAQS) Implementation Actions

EPA Pesticide Factsheets

Read about the EPA's infrastructure actions for the 2008 lead NAAQS. These actions are regarding states' failure to submit SIPs addressing various parts of the standards. Here you can read the federal register notices, fact sheets, and the docket folder.

1997 Ozone National Ambient Air Quality Standards (NAAQS) Infrastructure Actions

EPA Pesticide Factsheets

Read about the EPA's infrastructure actions for the 1997 Ozone NAAQS. These actions are regarding states' failure to submit SIPs addressing various parts of the standards. Here you can read the federal register notices, fact sheets, and the docket folder.

2008 Ozone National Ambient Air Quality Standards (NAAQS) Infrastructure Actions

EPA Pesticide Factsheets

Read about the EPA's infrastructure actions for the 2008 Ozone NAAQS. These actions are regarding states' failure to submit SIPs addressing various parts of the standards. Here you can read the federal register notices, fact sheets, and the docket folder.

5 CFR 850.103 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-01-01

... graphical image of a handwritten signature, usually created using a special computer input device, such as a... comparison with the characteristics and biometric data of a known or exemplar signature image. Director means... folder across the Government. Electronic retirement and insurance processing system means the new...

5 CFR 850.103 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... graphical image of a handwritten signature, usually created using a special computer input device, such as a... comparison with the characteristics and biometric data of a known or exemplar signature image. Director means... folder across the Government. Electronic retirement and insurance processing system means the new...

5 CFR 850.103 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-01-01

... graphical image of a handwritten signature, usually created using a special computer input device, such as a... comparison with the characteristics and biometric data of a known or exemplar signature image. Director means... folder across the Government. Electronic retirement and insurance processing system means the new...

The John Milner Nutrition and Cancer Prevention Research Practicum | Division of Cancer Prevention

Cancer.gov

Attendee Testimonial Plenty of Food for Thought Served Up at the John Milner Nutrition and Cancer Prevention Research Practicum by Julia Tobacyk Media Folder: research_groupView the Testimonial (PDF, 790 KB) Date: March 12-16, 2018 |

Great Lakes: Great Gardening.

ERIC Educational Resources Information Center

New York Sea Grant Inst., Albany, NY.

This folder contains 12 fact sheets designed to improve the quality of gardens near the Great Lakes. The titles are: (1) "Your Garden and the Great Lakes"; (2) "Organic Gardening"; (3) "Fruit and Vegetable Gardening"; (4) "Composting Yard Wastes"; (5) "Herbicides and Water Quality"; (6)…

5 CFR 293.301 - Applicability of regulations.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Applicability of regulations. 293.301 Section 293.301 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL RECORDS Official Personnel Folder § 293.301 Applicability of regulations. This subpart applies to...

5 CFR 293.301 - Applicability of regulations.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Applicability of regulations. 293.301 Section 293.301 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL RECORDS Official Personnel Folder § 293.301 Applicability of regulations. This subpart applies to...

2012 PM National Ambient Air Quality Standards (NAAQS) Nonattainment Actions

EPA Pesticide Factsheets

Read about the EPA's infrastructure actions for the 2008 Ozone NAAQS. These actions are regarding states' failure to submit SIPs addressing various parts of the standards. Here you can read the federal register notices, fact sheets, and the docket folder.

Development of a liposome microbicide formulation for vaginal delivery of octylglycerol for HIV prevention

PubMed Central

Wang, Lin; Sassi, Alexandra Beumer; Patton, Dorothy; Isaacs, Charles; Moncla, B. J.; Gupta, Phalguni; Rohan, Lisa Cencia

2015-01-01

The feasibility of using a liposome drug delivery system to formulate octylglycerol (OG) as a vaginal microbicide product was explored. A liposome formulation was developed containing 1% OG and phosphatidyl choline in a ratio that demonstrated in vitro activity against Neisseria gonorrhoeae, HSV-1, HSV-2 and HIV-1 while sparing the innate vaginal flora, Lactobacillus. Two conventional gel formulations were prepared for comparison. The OG liposome formulation with the appropriate OG/lipid ratio and dosing level had greater efficacy than either conventional gel formulation and maintained this efficacy for at least 2 months. No toxicity was observed for the liposome formulation in ex vivo testing in a human ectocervical tissue model or in vivo testing in the macaque safety model. Furthermore, minimal toxicity was observed to lactobacilli in vitro or in vivo safety testing. The OG liposome formulation offers a promising microbicide product with efficacy against HSV, HIV and N. gonorrhoeae. PMID:22149387

VizieR Online Data Catalog: SDSS DR7 voids and superclusters (Nadathur+, 2014)

NASA Astrophysics Data System (ADS)

Nadathur, S.; Hotchkiss, S.

2016-02-01

This is a public catalogue of voids and superclusters identified in the SDSS DR7 main galaxy and luminous red galaxy samples. This version is dated 04.11.2013. We make the catalogues available for general use. If you use them for your own work, we ask that you cite the original paper, Nadathur & Hotchkiss (2014MNRAS.440.1248N). The top-level directory cat_v11.11.13 contains an example python script called postproc.py, and two folders called comovcoords and redshiftcoords containing two versions of the catalogue in different coordinate systems. The comoving coordinate system is pretty self-explanatory, for a description of the other one please refer to the paper. Each of these directories is further divided into six folders containing the Type1 and Type2 void catalogues and the supercluster catalogue for each of the galaxy samples analysed here, and a folder called tools, which contains data useful for users wishing to apply their own selection criteria. The basic information provided includes the location of the barycentre of each structure, its volume, effective radius, average density and minimum or maximum density, its core galaxy and seed zone, the total number of galaxies in the seed zone, the number of zones merged to form the structure, the total number of particles in the structure, and its density ratio. These are split between two files for each structure type and each sample, named xxxinfo.txt and xxxlist.txt, where xxx refers to the structure type. It is also possible to extract lists of member galaxies of each structure and their magnitudes. An example python script, postproc.py, demonstrates how to access this information and how to build alternative catalogues using user-defined selection criteria. (27 data files).

The medical folder as an active tool in defining the clinical decision-making process.

PubMed

Ferri, F

1995-01-01

Whenever the user of a consultation system needs to know a large amount of information items that are possibly inter-related, a system that is able to cooperate with the user can simplify the interaction and increase its speed. In fact, these systems can recognize the goals of the user, individuate the information related to his goals, and finally focus their attention on this information [1]. This paper describes research work on the design and creation of a medical folder management system capable of establishing cooperative dialogue with users who have access to the information contained therein. Particular attention has thus been paid to the problems of man-computer dialogue and user models. The research work has addressed the problem of integrating into the system knowledge about the medical domain and users (physicians are only used for the time being), which are both necessary to activate a cooperative dialogue. After analysing the literature on the problems of user models, this paper presents and formalizes a study performed at the IVth Surgical Clinic of the Rome University Umberto I General Hospital to identify and represent how, when, and with what goals the physician consults the medical folder, as well as the dialogue procedures he normally adopts. The paper also illustrates important characteristics of the CADMIO prototype, which has been developed since the study was made. CADMIO stores information about users for use in recognizing and interpreting their behaviour, providing help, and in acquiring and returning further information. Whilst always bearing in mind the physician's pre-established goals, it structures information to facilitate his consultation activity, offering him options for the retrieval of further information semantically linked to that already obtained.

OGS Hydrogen Sensor ORU R&R

NASA Image and Video Library

2012-04-18

ISS030-E-236919 (18 April 2012) --- NASA astronaut Dan Burbank, Expedition 30 commander, works with the Oxygen Generator System (OGS) rack in the Tranquility node of the International Space Station. Burbank unpowered the OGS, purged the hydrogen sensor Orbital Replacement Unit (ORU) with the Hydrogen Sensor ORU Purge Adapter (HOPA) for return to Earth, and replaced the hydrogen sensor with a new spare, then cleaned the rack Avionics Air Assembly (AAA).

Decolorization of azo dyes Orange G using hydrodynamic cavitation coupled with heterogeneous Fenton process.

PubMed

Cai, Meiqiang; Su, Jie; Zhu, Yizu; Wei, Xiaoqing; Jin, Micong; Zhang, Haojie; Dong, Chunying; Wei, Zongsu

2016-01-01

The present work demonstrates the application of the combination of hydrodynamic cavitation (HC) and the heterogeneous Fenton process (HF, Fe(0)/H2O2) for the decolorization of azo dye Orange G (OG). The effects of main affecting operation conditions such as the inlet fluid pressure, initial concentration of OG, H2O2 and zero valent iron (ZVI), the fixed position of ZVI, and medium pH on decolorization efficiency were discussed with guidelines for selection of optimum parameters. The results revealed that the acidic conditions are preferred for OG decolorizaiton. The decolorization rate increased with increasing H2O2 and ZVI concentration and decreased with increasing OG initial concentration. Besides, the decolorization rate was strongly dependent on the fixed position of ZVI. The analysis results of degradation products using liquid chromatography-ESI-TOF mass spectrometry revealed that the degradation mechanism of OG proceeds mainly via reductive cleavage of the azo linkage due to the attack of hydroxyl radical. The present work has conclusively established that the combination of HC and HF can be more energy efficient and gives higher decolorization rate of OG as compared with HC and HF alone. Copyright © 2015 Elsevier B.V. All rights reserved.

Ultrasound enhanced activation of peroxydisulfate by activated carbon fiber for decolorization of azo dye.

PubMed

Huang, Tianyin; Zhang, Ke; Qian, Yajie; Fang, Cong; Chen, Jiabin

2018-02-20

Activated carbon fiber (ACF) has become an emerging activator for peroxydisulfate (PDS) to generate sulfate radical (SO 4 •- ). However, the relative low activation efficiency and poor contaminant mineralization limited its widespread application. Herein, ultrasound (US) was introduced to the ACF activated PDS system, and the synergistic effect of US and ACF in PDS activation and the enhancement of contaminant mineralization were investigated. The synergistic effect of US and ACF was observed in the PDS activation to decolorize orange G (OG). The decolorization efficiency increased with increasing ACF loading and US power, and PDS/OG ratio from 1 to 40. The activation energy was determined to be 24.065 kJ/mol. The radical-induced decolorization of OG took place on the surface of ACF, and both SO 4 •- and hydroxyl radical ( • OH) contributed to OG decolorization. The azo bond and naphthalene ring on OG were destructed to other aromatic intermediates and finally mineralized to CO 2 and H 2 O. The introduction of US in the ACF/PDS system significantly enhanced the mineralization of OG. The combination of US and PDS was highly efficient to activate PDS to decolorize azo dyes. Moreover, the introduction of US remarkably improved the contaminant mineralization.

Enhanced degradation of Orange G by permanganate with the employment of iron anode.

PubMed

Bu, Lingjun; Shi, Zhou; Zhou, Shiqing

2017-01-01

Iron anode was employed to enhance the degradation of Orange G (OG) by permanganate (EC/KMnO 4 ). Continuously generated Fe 2+ from iron anode facilitated the formation of fresh MnO 2 , which plays a role in catalyzing permanganate oxidation. The EC/KMnO 4 system also showed a better performance to remove OG than Fe 2+ /KMnO 4 , indicating the importance of in situ formed fresh MnO 2 . Besides, the effects of applied current, KMnO 4 dosage, solution pH, and natural organics were evaluated and results demonstrated that high current and oxidant dosage are favorable for OG removal. And the application of iron anode has a promoting effect on the KMnO 4 oxidation over a wide pH range (5.0-9.0), while the Fe 2+ /KMnO 4 process does not. For natural organics, its presence could inhibit OG removal due to its competitive role. And the promoting effect of OG removal by the EC/KMnO 4 process in natural water was confirmed. At last, the EC/KMnO 4 process showed a satisfying performance on the decolorization and mineralization of OG. This study provides a potential technology to enhance permanganate oxidation and broadens the knowledge of azo dye removal.

Outcomes following neonatal cardiopulmonary resuscitation.

PubMed

Boldingh, Anne Marthe; Solevåg, Anne Lee; Nakstad, Britt

2018-05-29

Hjerte-lunge-redning av et kritisk sykt barn ved fødsel kan føre til overlevelse eller død. De som overlever kan utvikle komplikasjoner direkte etter fødsel eller senere i småbarns- og skolealder. Hypoksisk iskemisk encefalopati er en tilstand med nevrologiske symptomer hos den nyfødte etter hypoksi ved fødsel. Tilstanden klassifiseres som mild, moderat eller alvorlig. Vi ønsket å gi en oversikt over kort- og langtidsutfall etter hjerte-lunge-redning ved fødsel. Vi søkte i databasen Medline for utfall etter hjerte-lunge-redning ved fødsel. Vi identifiserte 15 indekserte, fagfellevurderte originalartikler og to metaanalyser om utfall etter hjerte-lunge-redning ved fødsel eller fødselsasfyksi. Hypoksisk iskemisk encefalopati rammer generelt 38 % av pasientene i mild til moderat grad og 23 % i alvorlig grad. Dødeligheten varierte fra 10 % i høy- til 28 % i lavinntektsland. Overlevende utvikler ofte motoriske, kognitive og sensoriske utviklingshemninger. I noen tilfeller blir det først avdekket ved skolestart når mer komplekse ferdigheter kreves. Funksjonshemning ved skolealder er sterkt korrelert til tilstanden i småbarnsalder. Endringer i algoritmene ved hjerte-lunge-redning og rutinebehandling med hypotermi har redusert risikoen for alvorlige følgetilstander etter hypoksisk iskemisk encefalopati.

Anxiolytic effects of orcinol glucoside and orcinol monohydrate in mice.

PubMed

Wang, Xiaohong; Li, Guiyun; Li, Peng; Huang, Linyuan; Huang, Jianmei; Zhai, Haifeng

2015-06-01

Anxiety is a common psychological disorder, often occurring in combination with depression, but therapeutic drugs with high efficacy and safety are lacking. Orcinol glucoside (OG) was recently found to have an antidepressive action. To study the therapeutic potential of OG and orcinol monohydrate (OM) as anxiolytic agents. Anxiolytic effects in mice were measured using the elevated plus-maze, hole-board, and open-field tests. Eight groups of mice were included in each test. Thirty minutes before each test, mice in each group received one oral administration of OG (5, 10, or 20 mg/kg), OM (2.5, 5, or 10 mg/kg), the positive control diazepam (1 or 5 mg/kg), or control vehicle. Each mouse underwent only one test. Uptake of orcinol (5 mg/kg) in the brain was qualitatively detected using the HPLC-MS method. OG (5, 10, and 20 mg/kg) and OM (2.5 and 5 mg/kg) increased the time spent in open arms and the number of entries into open arms in the elevated plus-maze test. OG (5 and 10 mg/kg) and OM (2.5 and 5 mg/kg) increased the number of head-dips in the hole-board test. At all tested doses, OG and OM did not significantly affect the locomotion of mice in the open-field test. Orcinol could be detected in the mouse brain homogenates 30 min after oral OM administration, having confirmed that OM is centrally active. The results demonstrated that OG and OM are anxiolytic agents without sedative effects, indicating their therapeutic potential for anxiety.

Validation of the American Board of Orthodontics Objective Grading System for assessing the treatment outcomes of Chinese patients.

PubMed

Song, Guang-Ying; Baumrind, Sheldon; Zhao, Zhi-He; Ding, Yin; Bai, Yu-Xing; Wang, Lin; He, Hong; Shen, Gang; Li, Wei-Ran; Wu, Wei-Zi; Ren, Chong; Weng, Xuan-Rong; Geng, Zhi; Xu, Tian-Min

2013-09-01

Orthodontics in China has developed rapidly, but there is no standard index of treatment outcomes. We assessed the validity of the American Board of Orthodontics Objective Grading System (ABO-OGS) for the classification of treatment outcomes in Chinese patients. We randomly selected 108 patients who completed treatment between July 2005 and September 2008 in 6 orthodontic treatment centers across China. Sixty-nine experienced Chinese orthodontists made subjective assessments of the end-of-treatment casts for each patient. Three examiners then used the ABO-OGS to measure the casts. Pearson correlation analysis and receiver operating characteristic curve analysis were conducted to evaluate the correspondence between the ABO-OGS cast measurements and the orthodontists' subjective assessments. The average subjective grading scores were highly correlated with the ABO-OGS scores (r = 0.7042). Four of the 7 study cast components of the ABO-OGS score-occlusal relationship, overjet, interproximal contact, and alignment-were statistically significantly correlated with the judges' subjective assessments. Together, these 4 accounted for 58% of the variability in the average subjective grading scores. The ABO-OGS cutoff score for cases that the judges deemed satisfactory was 16 points; the corresponding cutoff score for cases that the judges considered acceptable was 21 points. The ABO-OGS is a valid index for the assessment of treatment outcomes in Chinese patients. By comparing the objective scores on this modification of the ABO-OGS with the mean subjective assessment of a panel of highly qualified Chinese orthodontists, a cutoff point for satisfactory treatment outcome was defined as 16 points or fewer, with scores of 16 to 21 points denoting less than satisfactory but still acceptable treatment. Cases that scored greater than 21 points were considered unacceptable. Copyright © 2013 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved.

A fast visual evoked potential method for functional assessment and follow-up of childhood optic gliomas.

PubMed

Trisciuzzi, Maria Teresa S; Riccardi, Riccardo; Piccardi, Marco; Iarossi, Giancarlo; Buzzonetti, Luca; Dickmann, Anna; Colosimo, Cesare; Ruggiero, Antonio; Di Rocco, Concezio; Falsini, Benedetto

2004-01-01

To evaluate a fast technique of visual evoked potentials (VEPs) recording, in response to steady-state luminance stimuli (SS-LVEPs), for functional assessment and follow-up of childhood optic gliomas (OGs). Eighteen OG patients (age range: 3.5-18 years), with different degrees of optic pathway damage severity, were examined. Sixteen age-matched normal subjects served as controls. Ten of the 18 OG patients were re-tested 1-3 months after the first examination. SS-LVEPs were elicited by a sinusoidally-modulated flickering (8 Hz) uniform field, generated by a light emitting diode (LED)-array and presented monocularly in a mini-ganzfeld. Amplitude and phase of the Fourier-analyzed response fundamental (1F) and second harmonic (2F) were measured. The full VEP protocol had a median duration of 6 min (range: 4-12). When compared to normal control values, median 1F and 2F SS-LVEP amplitudes of OG patients were reduced (P<0.01), with a borderline increase in 2F phase lag (P<0.05). In 11 OG patients with asymmetric optic pathway damage in between-eye comparisons, median 1F amplitude losses were greater (P<0.01) in fellow eyes with more severe damage. No significant interocular difference was observed in control subjects. Median test-retest changes of 1F and 2F component were <20% and 30 degrees for amplitude and phase, respectively. In individual OG patients, 1F and 2F amplitudes were positively correlated (P<0.01) with visual acuity. 1F amplitude losses were correlated (P=0.01) with the severity of optic disc atrophy. Considering both 1F and 2F abnormalities, diagnostic sensitivity of SS-LVEP in detecting OG-induced optic pathways damage was 83.3%. The present findings support the use of this technique, as an alternative to pattern VEPs, for functional assessment and follow-up of OG in uncooperative children.

OGS improvements in 2012 in running the Northeastern Italy Seismic Network: the Ferrara VBB borehole seismic station

NASA Astrophysics Data System (ADS)

Pesaresi, Damiano; Romanelli, Marco; Barnaba, Carla; Bragato, Pier Luigi; Durì, Giorgio

2013-04-01

The Centro di Ricerche Sismologiche (CRS, Seismological Research Center) of the Istituto Nazionale di Oceanografia e di Geofisica Sperimentale (OGS, Italian National Institute for Oceanography and Experimental Geophysics) in Udine (Italy) after the strong earthquake of magnitude M=6.4 occurred in 1976 in the Italian Friuli-Venezia Giulia region, started to operate the Northeastern Italy Seismic Network: it currently consists of 17 very sensitive broad band and 18 simpler short period seismic stations, all telemetered to and acquired in real time at the OGS-CRS data center in Udine. Real time data exchange agreements in place with other Italian, Slovenian, Austrian and Swiss seismological institutes lead to a total number of about 100 seismic stations acquired in real time, which makes the OGS the reference institute for seismic monitoring of Northeastern Italy. The southwestern edge of the OGS seismic network stands on the Po alluvial basin: earthquake localization and characterization in this area is affected by the presence of soft alluvial deposits. OGS ha already experience in running a local seismic network in high noise conditions making use of borehole installations in the case of the micro-seismicity monitoring of a local gas storage site for a private company. Following the ML=5.9 earthquake that struck the Emilia region around Ferrara in Northern Italy on May 20, 2012 at 02:03:53 UTC, a cooperation of Istituto Nazionale di Geofisica e Vulcanologia, OGS, the Comune di Ferrara and the University of Ferrara lead to the reinstallation of a previously existing very broad band (VBB) borehole seismic station in Ferrara. The aim of the OGS intervention was on one hand to extend its real time seismic monitoring capabilities toward South-West, including Ferrara and its surroundings, and on the other hand to evaluate the seismic response at the site. We will describe improvements in running the Northeastern Italy Seismic Network, including details of the Ferrara VBB borehole station configuration and installation, with first results.

Comparison of long-term results between laparoscopy-assisted gastrectomy and open gastrectomy with D2 lymph node dissection for advanced gastric cancer.

PubMed

Hamabe, Atsushi; Omori, Takeshi; Tanaka, Koji; Nishida, Toshirou

2012-06-01

Laparoscopy-assisted gastrectomy (LAG) has been established as a low-invasive surgery for early gastric cancer. However, it remains unknown whether it is applicable also for advanced gastric cancer, mainly because the long-term results of LAG with D2 lymph node dissection for advanced gastric cancer have not been well validated compared with open gastrectomy (OG). A retrospective cohort study was performed to compare LAG and OG with D2 lymph node dissection. For this study, 167 patients (66 LAG and 101 OG patients) who underwent gastrectomy with D2 lymph node dissection for advanced gastric cancer were reviewed. Recurrence-free survival and overall survival time were estimated using Kaplan-Meier curves. Stratified log-rank statistical evaluation was used to compare the difference between the LAG and OG groups stratified by histologic type, pathologic T status, N status, and postoperative adjuvant chemotherapy. The adjusted Cox proportional hazards regression models were used to calculate the hazard ratios (HRs) of LAG. The 5-year recurrence-free survival rate was 89.6% in the LAG group and 75.8% in the OG group (nonsignificant difference; stratified log-rank statistic, 3.11; P = 0.0777). The adjusted HR of recurrence for LAG compared with OG was 0.389 [95% confidence interval (CI) 0.131-1.151]. The 5-year overall survival rate was 94.4% in the LAG group and 78.5% in the OG group (nonsignificant difference; stratified log-rank statistic, 0.4817; P = 0.4877). The adjusted HR of death for LAG compared with OG was 0.633 (95% CI 0.172-2.325). The findings show that LAG with D2 lymph node dissection is acceptable in terms of long-term results for advanced gastric cancer cases and may be applicable for advanced gastric cancer treatment.

Comparing Top-down and Bottom-up Estimates of Methane Emissions across Multiple U.S. Basins Provides Insights into National Oil and Gas Emissions and Mitigation Strategies

NASA Astrophysics Data System (ADS)

Hamburg, S.; Alvarez, R.; Lyon, D. R.; Zavala-Araiza, D.

2016-12-01

Several recent studies quantified regional methane emissions in U.S. oil and gas (O&G) basins using top-down approaches such as airborne mass balance measurements. These studies apportioned total methane emissions to O&G based on hydrocarbon ratios or subtracting bottom-up estimates of other sources. In most studies, top-down estimates of O&G methane emissions exceeded bottom-up emission inventories. An exception is the Barnett Shale Coordinated Campaign, which found agreement between aircraft mass balance estimates and a custom emission inventory. Reconciliation of Barnett Shale O&G emissions depended on two key features: 1) matching the spatial domains of top-down and bottom-up estimates, and 2) accounting for fat-tail sources in site-level emission factors. We construct spatially explicit custom emission inventories for domains with top-down O&G emission estimates in eight major U.S. oil and gas production basins using a variety of data sources including a spatially-allocated U.S. EPA Greenhouse Gas Inventory, the EPA Greenhouse Gas Reporting Program, state emission inventories, and recently published measurement studies. A comparison of top-down and our bottom-up estimates of O&G emissions constrains the gap between these approaches and elucidates regional variability in production-normalized loss rates. A comparison of component-level and site-level emission estimates of production sites in the Barnett Shale region - where comprehensive activity data and emissions estimates are available - indicates that abnormal process conditions contribute about 20% of regional O&G emissions. Combining these two analyses provides insights into the relative importance of different equipment, processes, and malfunctions to emissions in each basin. These data allow us to estimate the U.S. O&G supply chain loss rate, recommend mitigation strategies to reduce emissions from existing infrastructure, and discuss how a similar approach can be applied internationally.

An evaluation of an immunomodulatory feed ingredient in heat-stressed lactating Holstein cows: Effects on hormonal, physiological, and production responses.

PubMed

Hall, L W; Villar, F; Chapman, J D; McLean, D J; Long, N M; Xiao, Y; Collier, J L; Collier, R J

2018-06-06

Holstein cows (n = 30) were balanced by days in milk, milk production, and parity (91 ± 5.9 d in milk, 36.2 ± 2.5 kg/d, and 3.1 ± 1.4, respectively) and fed OmniGen-AF (OG; Phibro Animal Health, Teaneck, NJ), an immune stimulant, at 0 g/cow per d for control (CON) or 56 g/cow per d for OG for 52 d on a commercial dairy. At 52 d of the study cows were randomly selected (n = 12) from both groups (6 OG and 6 CON) and housed in environmentally controlled rooms at the Agricultural Research Complex for 21 d at the University of Arizona. Cows were subjected to 7 d of thermoneutral (TN) conditions, 10 d of heat stress (HS), and 4 d of recovery (REC) under TN conditions. Feed intake, milk production, and milk composition were measured daily. Rectal temperatures (RT) and respiration rates (RR) were recorded 3 times per day (600, 1400, and 1800 h). Blood samples were taken on d 7 (TN), 8 (HS), 10 (HS), 17 (HS), and 18 (TN) during the Agricultural Research Complex segment. Cows in HS had higher RR and RT and water intake and lower dry matter intake and milk yield than these measures in TN. There was a treatment × environment interaction with cows fed OG having lower RR and RT and higher dry matter intake during peak thermal loads than CON. However, milk yield did not differ between groups. Cows fed OG had lower milk fat percent than CON (3.7 vs 4.3%) during HS. The SCC content of milk did not differ between treatment groups but rose in both groups during the REC phase following HS. Plasma insulin and plasma glucose levels were not different between groups. However, plasma insulin in both groups was lower during acute HS, then rose across the HS period, and was highest during the REC phase. Plasma cortisol levels were highest in all cows on the first day of HS (d 8) but were lower in cows fed OG compared with CON. However, plasma ACTH concentrations were elevated in OG-fed animals at all times samples were collected. Plasma ACTH was also elevated in cows fed both OG and CON during HS. Feeding OG reduced plasma cortisol during acute but not chronic HS and increased basal plasma ACTH, suggesting that OG treatment may alter the hypothalamic pituitary adrenal axis. Copyright © 2018 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

The future of transportation starts here : intelligent transportation systems

DOT National Transportation Integrated Search

1998-01-01

This "Vision Folder" contains the following items: FHWA-JPO-98-008, a 16-page brochure entitled "You Are About to Enter the Age of Intelligent Transportation" (see TRIS 00746661); FHWA-JPO-98-019, a 2-page fact sheet entitled "The National ITS Archit...

77 FR 9902 - Privacy Act of 1974; System of Records

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-21

... effective on March 22, 2012 unless comments are received that would result in a contrary determination... or status, name, Social Security Number (SSN), gender, medical diagnosis, medical condition, special...: Delete entry and replace with ``Paper records in file folders and electronic storage media...

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2010-06-15

... be effective without further notice on July 15, 2010 unless comments are received which result in a... of records in the system: Storage: Paper files folders and electronic storage media. Retrievability... categories: Individual, social workers, rehabilitation counselors, and/or health care personnel. Exemptions...

Installing and Setting Up Git Software Tool on Windows | High-Performance

Science.gov Websites

projects somewhere. In this example, we'll put our work in a "projects" folder inside the " GIT bash options. We'll also assume you'll want to start-off using the GUI. In our example, we've

78 FR 52607 - Unified Registration System

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-23

...'' and click ``Search.'' Next, click ``Open Docket Folder'' in the ``Actions'' column. Finally, in the... comments received are posted without change to http://www.regulations.gov . Anyone is able to search the... License CFR Code of Federal Regulations CMV Commercial Motor Vehicle CR Compliance Review CSA Compliance...

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Science.gov Websites

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77 FR 65047 - Agency Information Collection Activities: Proposed Request

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78 FR 24069 - Safety Zone; 12th Annual Saltwater Classic; Port Canaveral Harbor; Port Canaveral, FL

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76 FR 64115 - Privacy Act of 1974; Privacy Act System of Records

Federal Register 2010, 2011, 2012, 2013, 2014

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...-leaf binders or file folders, and in electronic media, including NASA's Ethics Program Tracking System... documents, electronic media, micrographic media, photographs, or motion pictures film, and various medical....; General Accounting Office's General Policies/Procedures and Communications Manual, Chapter 7; Treasury...

Business Portfolio Folder.

ERIC Educational Resources Information Center

Missouri Univ., Columbia. Instructional Materials Lab.

This chart is intended to document a student's mastery of competencies identified as necessary in the Missouri Competency Profile for business education. The chart includes space for recording basic student and instructor information and the student's on-the-job training and work experience. Provided next are rating sheets for various…

Making a report of a short trip in an ophiolitic complex with Google Earth

NASA Astrophysics Data System (ADS)

Aubret, Marianne

2017-04-01

Plate tectonics is taught in French secondary school (lower and upper-sixth). According to the curriculum, the comprehension of plate-tectonic processes and concepts should be based on field data. For example, the Alpine's ocean history is studied to understand how mountain ranges are formed. In this context, Corsica is a great open-air laboratory, but unfortunately, the traffic conditions are very difficult in the island and despite the short distances, it's almost impossible for teachers to take their students to the remarkable geologic spots. The «défilé de l'Inzecca» is one of them: there you can see a part of the alpine's ophiolitic complex. The aim of this activity is to elaborate a « KMZ folder » in Google Earth as a report of a short trip thanks to the students' data field; it is also the occasion to enrich the Google Earth KMZ folder already available for our teaching.

[Importance of an outpatient record in obstetric anesthesia].

PubMed

Lanza, V; Mercadante, S; Pignataro, A; Guglielmo, L; Villari, P; Di Fiore, G; Sapio, M; De Michele, P; Vegna, G

1991-01-01

A computerised record was used to collect data following an anesthesiological check-up of pregnant women at approximately 30 weeks of pregnancy. The record was input onto a portable PC in the anesthesia outpatient clinic, memorized on disk (3.5") and then transferred onto a PC network (one PC for each operating theatre) for "real time" consultation of each patient's data. All pregnant women attending the antenatal clinico were also given a folder illustrating epidural anesthetic techniques. Seven hundred and nine outpatient visits have been performed over the past two years with a 62% utilisation ratio. The collection of data using a computerised system allows a rapid and efficacious system of communication to be set up among the membranes of the anesthesiological team, thus encouraging the use of epidural techniques during labour. The distribution of the folder also facilitated the task of the anesthetist who found that pregnant women visiting the anesthesia clinic were already familiar with the epidural technique.

Crown oxygen-doping graphene with embedded main-group metal atoms

NASA Astrophysics Data System (ADS)

Wu, Liyuan; Wang, Qian; Yang, Chuanghua; Quhe, Ruge; Guan, Pengfei; Lu, Pengfei

2018-02-01

Different main-group metal atoms embedded in crown oxygen-doping graphene (metal@OG) systems are studied by the density functional theory. The binding energies and electronic structures are calculated by using first-principles calculations. The binding energy of metal@OG system mainly depends on the electronegativity of the metal atom. The lower the value of the electronegativity, the larger the binding energy, indicating the more stable the system. The electronic structure of metal@OG arouses the emergence of bandgap and shift of Dirac point. It is shown that interaction between metal atom and crown oxygen-doping graphene leads to the graphene's stable n-doping, and the metal@OG systems are stable semiconducting materials, which can be used in technological applications.

Earth Observation

NASA Image and Video Library

2014-09-01

Earth Observation taken during a night pass by the Expedition 40 crew aboard the International Space Station (ISS). Folder lists this as: New Zealand Aurora night pass. Docked Soyuz and Progress spacecraft are visible. On crewmember's Flickr page - The Moon, about to dive into a glowing ocean of green᥿9.

38 CFR 1.521 - Special restrictions concerning social security records.

Code of Federal Regulations, 2011 CFR

2011-07-01

... concerning social security records. 1.521 Section 1.521 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF... Records § 1.521 Special restrictions concerning social security records. Information received from the Social Security Administration may be filed in the veteran's claims folder without special provisions...

75 FR 6000 - Privacy Act of 1974; Systems of Records

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-05

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Specific Job Competencies.

ERIC Educational Resources Information Center

Seattle Community Coll. District, Washington.

This document consists of 12 separate folders each listing a set of job competencies for a specific occupation or function area (e.g. television, wood construction) that is the subject of vocational and technical education courses at the middle and high school level in the Seattle (Washington) Public Schools Vocational/Technical Education…

7. Photocopied August 1971 from Photo 13729, Granite Station Special ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

7. Photocopied August 1971 from Photo 13729, Granite Station Special Folder, Engineering Department, Utah Power and Light Co., Salt Lake City, Utah. GRANITE HYDRO-ELECTRIC PLANT (1500KW) STATION. PENSTOCK AND SPILWAY, NOVEMBER 1914. - Utah Power Company, Granite Hydroelectric Plant, Holladay, Salt Lake County, UT

8. Photocopied August 1971 from Photo 11479, Granite Station Special ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

8. Photocopied August 1971 from Photo 11479, Granite Station Special Folder, Engineering Department, Utah Power and Light Co., Salt Lake City, Utah. GRANITE HYDRO-ELECTRIC PLANT (1500 KW) STATION. PENSTOCK AND SPILWAY, NOVEMBER 1914. - Utah Power Company, Granite Hydroelectric Plant, Holladay, Salt Lake County, UT

7. Photocopied August 1971 from Photo 11480, Stairs Station Special ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

7. Photocopied August 1971 from Photo 11480, Stairs Station Special Folder, Engineering Department, Utah Power and Light Co., Salt Lake City, Utah. STAIRS HYDRO-ELECTRIC PLANT (1600 KW) STATION AND PENSTOCK, NOVEMBER 1914. - Utah Power & Light Company, Stairs Hydroelectric Station, Holladay, Salt Lake County, UT

45 CFR 1210.3-11 - Disposition of termination and appeal files.

Code of Federal Regulations, 2012 CFR

2012-10-01

... FOR NATIONAL AND COMMUNITY SERVICE VISTA TRAINEE DESELECTION AND VOLUNTEER EARLY TERMINATION PROCEDURES VISTA Volunteer Early Termination § 1210.3-11 Disposition of termination and appeal files. All... successful termination appeal may be made part of, or included in, a Volunteer's official folder. ...

45 CFR 1210.3-11 - Disposition of termination and appeal files.

Code of Federal Regulations, 2013 CFR

2013-10-01

... FOR NATIONAL AND COMMUNITY SERVICE VISTA TRAINEE DESELECTION AND VOLUNTEER EARLY TERMINATION PROCEDURES VISTA Volunteer Early Termination § 1210.3-11 Disposition of termination and appeal files. All... successful termination appeal may be made part of, or included in, a Volunteer's official folder. ...

45 CFR 1210.3-11 - Disposition of termination and appeal files.

Code of Federal Regulations, 2010 CFR

2010-10-01

... FOR NATIONAL AND COMMUNITY SERVICE VISTA TRAINEE DESELECTION AND VOLUNTEER EARLY TERMINATION PROCEDURES VISTA Volunteer Early Termination § 1210.3-11 Disposition of termination and appeal files. All... successful termination appeal may be made part of, or included in, a Volunteer's official folder. ...

45 CFR 1210.3-11 - Disposition of termination and appeal files.

Code of Federal Regulations, 2011 CFR

2011-10-01

... FOR NATIONAL AND COMMUNITY SERVICE VISTA TRAINEE DESELECTION AND VOLUNTEER EARLY TERMINATION PROCEDURES VISTA Volunteer Early Termination § 1210.3-11 Disposition of termination and appeal files. All... successful termination appeal may be made part of, or included in, a Volunteer's official folder. ...

45 CFR 1210.3-11 - Disposition of termination and appeal files.

Code of Federal Regulations, 2014 CFR

2014-10-01

... FOR NATIONAL AND COMMUNITY SERVICE VISTA TRAINEE DESELECTION AND VOLUNTEER EARLY TERMINATION PROCEDURES VISTA Volunteer Early Termination § 1210.3-11 Disposition of termination and appeal files. All... successful termination appeal may be made part of, or included in, a Volunteer's official folder. ...

Abuse Prevention Policy on Alcohol and Other Drugs.

ERIC Educational Resources Information Center

Mississippi Univ., University.

This document presents the University of Mississippi's campus drug and alcohol prevention policy. A four page folder details policy and regulations including: Mississippi law regarding alcohol and other drugs (e.g., penalties for trafficking and possession), university disciplinary sanctions, health risks of drug abuse, and counseling and…

The Bases of Teacher Expectancies: A Meta-Analysis.

ERIC Educational Resources Information Center

Dusek, Jerome B.; Joseph, Gail

1983-01-01

A meta-analysis of 77 studies on teacher expectancies led to the following conclusions: student attractiveness, conduct, cumulative folder information, race, and social class were related to teacher expectancies. Student gender and the number of parents at home were not related to teacher expectancies. (Author/LC)

76 FR 66695 - Privacy Act of 1974; System of Records

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-27

.... DWHS P04 System name: Reduction-In-Force Case Files (February 11, 2011, 76 FR 7825). Changes....'' * * * * * DWHS P04 System name: Reduction-In-Force Case Files. System location: Human Resources Directorate... system: Storage: Paper file folders. Retrievability: Filed alphabetically by last name. Safeguards...

38 CFR 1.521 - Special restrictions concerning social security records.

Code of Federal Regulations, 2012 CFR

2012-07-01

... concerning social security records. 1.521 Section 1.521 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF... Records § 1.521 Special restrictions concerning social security records. Information received from the Social Security Administration may be filed in the veteran's claims folder without special provisions...

38 CFR 1.521 - Special restrictions concerning social security records.

Code of Federal Regulations, 2013 CFR

2013-07-01

... concerning social security records. 1.521 Section 1.521 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF... Records § 1.521 Special restrictions concerning social security records. Information received from the Social Security Administration may be filed in the veteran's claims folder without special provisions...

38 CFR 1.521 - Special restrictions concerning social security records.

Code of Federal Regulations, 2014 CFR

2014-07-01

... concerning social security records. 1.521 Section 1.521 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF... Records § 1.521 Special restrictions concerning social security records. Information received from the Social Security Administration may be filed in the veteran's claims folder without special provisions...

38 CFR 1.521 - Special restrictions concerning social security records.

Code of Federal Regulations, 2010 CFR

2010-07-01

... concerning social security records. 1.521 Section 1.521 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF... Records § 1.521 Special restrictions concerning social security records. Information received from the Social Security Administration may be filed in the veteran's claims folder without special provisions...

Location Capability and Site Characterization Installing a Borehole VBB Seismometer: the OGS Experience in Ferrara (Italy)

NASA Astrophysics Data System (ADS)

Pesaresi, D.; Barnaba, C.

2014-12-01

The Centro di Ricerche Sismologiche (CRS, Seismological Research Centre) of the Istituto Nazionale di Oceanografia e di Geofisica Sperimentale (OGS, Italian National Institute for Oceanography and Experimental Geophysics) in Udine (Italy) after the strong earthquake of magnitude M=6.4 occurred in 1976 in the Italian Friuli-Venezia Giulia region, started to operate the Northeastern Italy Seismic Network: it currently consists of 19 very sensitive broad band and 17 simpler short period seismic stations, all telemetered to and acquired in real time at the OGS CRS data centre in Udine. The southwestern edge of the OGS seismic network stands on the Po alluvial basin: earthquake localization and characterization in this area is affected by the presence of soft alluvial deposits. Following the ML=5.9 earthquake that struck the Emilia region around Ferrara in Northern Italy on May 20, 2012, a cooperation of Istituto Nazionale di Geofisica e Vulcanologia, OGS, the Comune di Ferrara and the University of Ferrara lead to the reinstallation of a previously existing very broad band (VBB) borehole seismic station in Ferrara and to the deployment of a temporary seismographic network consisting of eight portable seismological stations, to record the local earthquakes that occurred during the seismic sequence. The aim of the OGS intervention was on one hand to extend its real time seismic monitoring capabilities toward South-West, including Ferrara and its surroundings, and on the other hand to evaluate seismic site responses in the area. We will introduce details of the Ferrara VBB borehole station and the OGS temporary seismographic network configuration and installation. We will then illustrate the location capability performances, and finally we will shortly describe seismic site characterization with surface/borehole comparisons in terms of seismic noise, site amplification and resonance frequencies.

Extensive copy number variations in admixed Indian population of African ancestry: potential involvement in adaptation.

PubMed

Narang, Ankita; Jha, Pankaj; Kumar, Dhirendra; Kutum, Rintu; Mondal, Anupam Kumar; Dash, Debasis; Mukerji, Mitali

2014-11-13

Admixture mapping has been enormously resourceful in identifying genetic variations linked to phenotypes, adaptation, and diseases. In this study through analysis of copy number variable regions (CNVRs), we report extensive restructuring in the genomes of the recently admixed African-Indian population (OG-W-IP) that inhabits a highly saline environment in Western India. The study included subjects from OG-W-IP (OG), five different Indian and three HapMap populations that were genotyped using Affymetrix version 6.0 arrays. Copy number variations (CNVs) detected using Birdsuite were used to define CNVRs. Population structure with respect to CNVRs was delineated using random forest approach. OG genomes have a surprising excess of CNVs in comparison to other studied populations. Individual ancestry proportions computed using STRUCTURE also reveals a unique genetic component in OGs. Population structure analysis with CNV genotypes indicates OG to be distant from both the African and Indian ancestral populations. Interestingly, it shows genetic proximity with respect to CNVs to only one Indian population IE-W-LP4, which also happens to reside in the same geographical region. We also observe a significant enrichment of molecular processes related to ion binding and receptor activity in genes encompassing OG-specific CNVRs. Our results suggest that retention of CNVRs from ancestral natives and de novo acquisition of CNVRs could accelerate the process of adaptation especially in an extreme environment. Additionally, this population would be enormously useful for dissecting genes and delineating the involvement of CNVs in salt adaptation. © The Author(s) 2014. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

Differential Game Theory Application to Intelligent Missile Guidance

DTIC Science & Technology

2013-06-01

guidance (OG) and game theoretic guidance ( GTG ). One reason for this development is the fact that the implementation hardware for the guidance system has...state estimation techniques such as the Kalman Filter and others, it is now feasible to implement the OG, GTG and GTG +AI ‘intelligent’ guidance on...both PN and APN as special cases of OG and GTG ; this connection is further explored in this report. The desire to reduce weapon life-cycle cost

Three Years of on Orbit ISS Oxygen Generation System Operation 2007-2010

NASA Technical Reports Server (NTRS)

Diderich, Greg S.; Polis, Pete; VanKeuren, Steven P.; Erickson, Bob

2010-01-01

The International Space Station (ISS) United States Orbital Segment (USOS) Oxygen Generation System (OGS) has accumulated 240 days of continuous operation at varied oxygen production rates within the US Laboratory Module (LAB) since it was first activated in July 2007. OGS relocated from the ISS LAB to Node 3 during 20A Flight (February 2010). The OGS rack delivery was accelerated for on-orbit checkout in the LAB, and it was launched to ISS in July of 2006. During the on-orbit checkout interval within the LAB from July 2007 to October 2008, OGS operational times were limited by the quantity of feedwater in a Payload Water Reservoir (PWR) bag. Longer runtimes are now achievable due to the continuous feedwater availability after ULF2 delivery and activation of the USOS Water Recovery System (WRS) racks. OGS is considered a critical function to maintaining six crew capability. There have been a number of failures which interrupted or threatened to interrupt oxygen production. Filters in the recirculation loop have clogged and have been replaced, Hydrogen sensors have fallen out of specifications, a pump delta pressure sensor failed, a pump failed to start, and the voltage on the cell stack increased out of tolerance. This paper will discuss the operating experience and characteristics of the OGS, as well as operational issues and their resolution.

Effect of nutritional immunomodulation and heat stress during the dry period on subsequent performance of cows.

PubMed

Fabris, Thiago F; Laporta, Jimena; Corra, Fabiana N; Torres, Yazielis M; Kirk, David J; McLean, Derek J; Chapman, J D; Dahl, Geoffrey E

2017-08-01

Heat stress in dairy cows during the dry period impairs milk yield in the next lactation. Feeding OmniGen-AF (OG; Phibro Animal Health Corp., Teaneck, NJ) to lactating cows during heat stress may increase dry matter intake (DMI) and lowers respiration rate (RR) and rectal temperature (RT), but the effects in dry cows are not known. We hypothesized that OG supplementation before, during, and after the dry period (approximately 160 d total) would overcome the effects of heat stress and improve cow performance in the next lactation. Cows were randomly assigned to OG or control (placebo) treatments for the last 60 d in milk (DIM), based on mature-equivalent milk yield in the previous lactation. Cows were dried off 45 d before expected calving and randomly assigned to heat stress (HT) or cooling (CL) treatments. Thus, cows received dietary supplementation during late lactation before they were exposed to either CL or HT. After dry-off, treatment groups included heat stress with placebo (HT, only shade, 56 g/d of placebo, n = 17), HT with OG supplementation (HTOG, 56 g/d of OG, n = 19), cooling with placebo (CL, shade, fans, and soakers, 56 g/d of placebo, n = 16), and CL with OG supplementation (CLOG, 56 g/d of OG, n = 11). After parturition, all cows were kept under the same CL system and management, and all cows continued to receive OG or control treatment until 60 DIM. Cooling cows during the dry period reduced afternoon RT (CL vs. HT; 38.9 ± 0.05 vs. 39.3 ± 0.05°C) and RR (CL vs. HT; 45 ± 1.6 vs. 77 ± 1.6 breaths/min). Respiration rate was also decreased by OG supplementation under HT conditions (HTOG vs. HT; 69.7 ± 1.6 vs. 77.2 ± 1.6 breaths/min). An interaction was observed between OG supplementation and HT; HTOG cows tended to have lower morning RT compared with HT cows. During the dry period, OG reduced DMI relative to control cows. Birth weight was greater in calves from CL cows (CL vs. HT; 40.6 ± 1.09 vs. 38.7 ± 1.09 kg). No differences were detected among treatments in hematocrit, total protein, and body condition score. Cows offered CLOG, CL, and HTOG treatments had greater body weight during the dry period (794.9 ± 17.9, 746.8 ± 16.7, and 762.9 ± 14.9 kg, respectively) than HT cows (720 ± 16.2 kg). Gestation length was approximately 4 d longer for CL cows compared with HT cows. Cows offered CLOG, CL, and HTOG treatments produced more milk (41.3 ± 1.6, 40.7 ± 1.6, and 40.5 ± 1.6 kg/d, respectively) than HT treatment (35.9 ± 1.6 kg/d). Body weight after parturition and DMI were evaluated up to 60 DIM and averaged 661.5 ± 15.8 and 19.4 ± 0.7 kg/d, respectively, with no differences observed among treatments. These results confirm that exposure of dry cows to heat stress negatively affects milk yield in the subsequent lactation. Active cooling of dry cows and OG supplementation can reduce the negative effects of heat stress in the dry period on subsequent performance. Copyright © 2017 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

Weather in Motion.

ERIC Educational Resources Information Center

National Aeronautics and Space Administration, Washington, DC.

The ATS-111 weather satellite, launched on November 18, 1967, in a synchronous earth orbit 22,000 miles above the equator, is described in this folder. The description is divided into these topics: the satellite, the camera, the display, the picture information, and the beneficial use of the satellite. Photographs from the satellite are included.…

76 FR 7825 - Privacy Act of 1974; System of Records

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-11

... practices for storing, retrieving, accessing, retaining, and disposing of records in the system: Storage..., accessing, retaining, and disposing of records in the system: Storage: Paper file folders. Retrievability...; System of Records AGENCY: Office of the Secretary, DoD. ACTION: Notice to alter a system of records...

Fermilab Today - Troubleshooting

Science.gov Websites

Search GO Troubleshooting for Fermilab Today Fermilab Today is distributed via e-mail each morning by the same program. Internet service providers are aggressively filtering spam due to the proliferation of spam folder, mark it as "not spam" or as "safe" Send an e-mail to today@fnal.gov

78 FR 5792 - Privacy Act of 1974; System of Records

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-28

... be effective on February 28, 2013 unless comments are received which result in a contrary...: Delete entry and replace with ``Name, Social Security Number (SSN) and/or DoD ID Number, home address... ``Paper file folders and electronic storage media.'' * * * * * Safeguards: Delete entry and replace with...

78 FR 73516 - Privacy Act of 1974; System of Records

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-06

... proposed action will be effective on January 6, 2014 unless comments are received which result in a..., Social Security Number (SSN), and case docket number and may include the individual's home address and... entry and replace with ``Paper file folders and electronic storage media.'' Retrievability: Delete entry...

Software - Naval Oceanography Portal

Science.gov Websites

section Advanced Search... Sections Home Time Earth Orientation Astronomy Meteorology Oceanography Ice You are here: Home › USNO › Earth Orientation › Software USNO Logo USNO Navigation Earth Orientation Search databases Auxiliary Software Supporting Software Form Folder Earth Orientation Matrix Calculator

8. Photocopy of sketch from National Archives, Record Group 121, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

8. Photocopy of sketch from National Archives, Record Group 121, Box 123, Folder 1877-1886 Filed with telegram for Secretary of Treasury from J.V. Harris, Collector, March 30, 1886 SECOND-FLOOR PLAN - U. S. Navy Coal Depot & Storehouse, Front & Whitehead Streets, Key West, Monroe County, FL

41 CFR 101-25.107 - Guidelines for requisitioning and proper use of consumable or low cost items.

Code of Federal Regulations, 2011 CFR

2011-07-01

... needs. Attache cases, Ball point pens and refills, Brief cases, Binders, Carbon paper, Dictionaries, Felt tip markers, Felt tip pens and refills, File folders, Letterex, Letter openers, Pads (paper), Paper clips, Pencils, Pencil sharpeners, Portfolios (leather, plastic, and writing pads), Rubber bands...

41 CFR 101-25.107 - Guidelines for requisitioning and proper use of consumable or low cost items.

Code of Federal Regulations, 2012 CFR

2012-07-01

... needs. Attache cases, Ball point pens and refills, Brief cases, Binders, Carbon paper, Dictionaries, Felt tip markers, Felt tip pens and refills, File folders, Letterex, Letter openers, Pads (paper), Paper clips, Pencils, Pencil sharpeners, Portfolios (leather, plastic, and writing pads), Rubber bands...

41 CFR 101-25.107 - Guidelines for requisitioning and proper use of consumable or low cost items.

Code of Federal Regulations, 2014 CFR

2014-07-01

... needs. Attache cases, Ball point pens and refills, Brief cases, Binders, Carbon paper, Dictionaries, Felt tip markers, Felt tip pens and refills, File folders, Letterex, Letter openers, Pads (paper), Paper clips, Pencils, Pencil sharpeners, Portfolios (leather, plastic, and writing pads), Rubber bands...

41 CFR 101-25.107 - Guidelines for requisitioning and proper use of consumable or low cost items.

Code of Federal Regulations, 2013 CFR

2013-07-01

... needs. Attache cases, Ball point pens and refills, Brief cases, Binders, Carbon paper, Dictionaries, Felt tip markers, Felt tip pens and refills, File folders, Letterex, Letter openers, Pads (paper), Paper clips, Pencils, Pencil sharpeners, Portfolios (leather, plastic, and writing pads), Rubber bands...

Cancer Biomarkers | Division of Cancer Prevention

Cancer.gov

[[{"fid":"175","view_mode":"default","fields":{"format":"default","field_file_image_alt_text[und][0][value]":"Cancer Biomarkers Research Group Homepage Logo","field_file_image_title_text[und][0][value]":"Cancer Biomarkers Research Group Homepage Logo","field_folder[und]":"15"},"type":"media","attributes":{"alt":"Cancer Biomarkers Research Group Homepage Logo","title":"Cancer

Gastrointestinal and Other Cancers | Division of Cancer Prevention

Cancer.gov

[[{"fid":"181","view_mode":"default","fields":{"format":"default","field_file_image_alt_text[und][0][value]":"Gastrointestinal and Other Cancers Research Group Homepage Logo","field_file_image_title_text[und][0][value]":"Gastrointestinal and Other Cancers Research Group Homepage Logo","field_folder[und]":"15"},"type":"media","attributes":{"alt":"Gastrointestinal and Other

Biometry | Division of Cancer Prevention

Cancer.gov

[[{"fid":"66","view_mode":"default","fields":{"format":"default","field_file_image_alt_text[und][0][value]":"Biometry Research Group Homepage Logo","field_file_image_title_text[und][0][value]":"Biometry Research Group Homepage Logo","field_folder[und]":"15"},"type":"media","attributes":{"alt":"Biometry Research Group Homepage Logo","title":"Biometry Research Group Homepage

How Forcefully Should Universities Enforce Copyright Law on Audio Files?

ERIC Educational Resources Information Center

McCollum, Kelly

1999-01-01

The Recording Industry Association of America is aggressively pursuing copyright violations on campuses concerning MP3 music recordings being exchanged on computer networks. Carnegie Mellon University (Pennsylvania), to avoid litigation, has been searching public folders of students' computers to find illegally copied MP3s. Controversy over…

77 FR 21057 - Short-Term Investment Funds

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-09

... companies, as defined by the RFA. No small national banks or federal branches and agencies report management..., click on ``Submit a Comment'' or ``Open Docket Folder'' to submit or view public comments and to view... also view or request available background documents and project summaries using the methods described...

Nuclear Energy and the Environment.

ERIC Educational Resources Information Center

International Atomic Energy Agency, Vienna (Austria).

"Nuclear Energy and the Environment" is a pocket folder of removable leaflets concerned with two major topics: Nuclear energy and Nuclear Techniques. Under Nuclear Energy, leaflets concerning the topics of "Radiation--A Fact of Life,""The Impact of a Fact: 1963 Test Ban Treaty,""Energy Needs and Nuclear Power,""Power Reactor Safety,""Transport,"…

5 CFR 532.279 - Special wage schedules for printing positions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Opaquer 4 Offset Press Helper 5 Bindery Machine Operator (Helper) 5 Film Assembler-Stripper (Single Flat-Single Color) 5 Platemaker (Single Color) 5 Film Assembler-Stripper (Partial and Composite Flats) 7... Cutter) 8 Bindery Machine Operator (Power Folder) 8 Film Assembler-Stripper (Multiple Flat-Multiple Color...

5 CFR 532.279 - Special wage schedules for printing positions.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Opaquer 4 Offset Press Helper 5 Bindery Machine Operator (Helper) 5 Film Assembler-Stripper (Single Flat-Single Color) 5 Platemaker (Single Color) 5 Film Assembler-Stripper (Partial and Composite Flats) 7... Cutter) 8 Bindery Machine Operator (Power Folder) 8 Film Assembler-Stripper (Multiple Flat-Multiple Color...

77 FR 67203 - Privacy Act of 1974; Republication of Systems of Records Notices

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-08

... file folders and on electronic media. RETRIEVABILITY: Accessed by name, tag number, and/or permit... DISPOSING OF RECORDS IN THE SYSTEM: STORAGE: Records are maintained on electronic media. RETRIEVABILITY... electronic media. RETRIEVABILITY: Records are accessed by individual action file number or by the name of the...

75 FR 36642 - Privacy Act of 1974; System of Records

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-28

... relating to the issue, return, and accountability of keys to secure areas. Records may contain name, Social... disposing of records in the system: Storage: Paper records in file folders and electronic storage media. Retrievability: By name, Social Security Number (SSN), key number, personal identification number (PIN), Magnetic...

Famous Threesomes: Uncommon Uses for Common Stories.

ERIC Educational Resources Information Center

Spears, Jo Ann Lohl

2003-01-01

This article presents a unit of fun and developmentally satisfying activities, using familiar folk stories focusing on threesomes. Each example involves story time, block center, art center, dramatic play, listening area, math and manipulatives center, folder game, group times, cooking, writing center, discovery center, and the music and movement…

OGS improvements in 2012 in running the North-eastern Italy Seismic Network: the Ferrara VBB borehole seismic station

NASA Astrophysics Data System (ADS)

Pesaresi, D.; Romanelli, M.; Barnaba, C.; Bragato, P. L.; Durì, G.

2014-07-01

The Centro di Ricerche Sismologiche (CRS, Seismological Research Centre) of the Istituto Nazionale di Oceanografia e di Geofisica Sperimentale (OGS, Italian National Institute for Oceanography and Experimental Geophysics) in Udine (Italy) after the strong earthquake of magnitude M=6.4 occurred in 1976 in the Italian Friuli-Venezia Giulia region, started to operate the North-eastern Italy Seismic Network: it currently consists of 17 very sensitive broad band and 18 simpler short period seismic stations, all telemetered to and acquired in real time at the OGS-CRS data centre in Udine. Real time data exchange agreements in place with other Italian, Slovenian, Austrian and Swiss seismological institutes lead to a total number of about 100 seismic stations acquired in real time, which makes the OGS the reference institute for seismic monitoring of North-eastern Italy. The south-western edge of the OGS seismic network (Fig. 1) stands on the Po alluvial basin: earthquake localization and characterization in this area is affected by the presence of soft alluvial deposits. OGS ha already experience in running a local seismic network in high noise conditions making use of borehole installations in the case of the micro-seismicity monitoring of a local gas storage site for a private company. Following the ML = 5.9 earthquake that struck the Emilia region around Ferrara in Northern Italy on 20 May 2012 at 02:03:53 UTC, a cooperation of Istituto Nazionale di Geofisica e Vulcanologia, OGS, the Comune di Ferrara and the University of Ferrara lead to the reinstallation of a previously existing very broad band (VBB) borehole seismic station in Ferrara. The aim of the OGS intervention was on one hand to extend its real time seismic monitoring capabilities toward South-West, including Ferrara and its surroundings, and on the other hand to evaluate the seismic response at the site. We will describe improvements in running the North-eastern Italy Seismic Network, including details of the Ferrara VBB borehole station configuration and installation, with first results.

Analysis of factors related to vagally mediated reflex bradycardia during gastrectomy.

PubMed

Kim, Duk-Kyung; Ahn, Hyun Joo; Lee, Seung Won; Choi, Ji Won

2015-12-01

Because vagally mediated reflex bradycardia occurs frequently during gastrectomy and is potentially harmful, we compared the incidence of clinically significant reflex bradycardia between patients undergoing laparoscopic gastrectomy (LG) and open gastrectomy (OG) and examined whether the type of surgery (OG vs. LG) was an independent risk factor for clinically significant reflex bradycardia. This prospective observational study evaluated 358 adult patients (age 18-70 years) who were undergoing elective OG or LG for gastric cancer resection. Symptomatic reflex bradycardia was defined as a sudden decrease in heart rate to <50 beats per minute (bpm), or to 50-59 bpm with a systolic blood pressure <70 mmHg, associated with a specific surgical maneuver. If bradycardia or hypotension developed, atropine or ephedrine was administered, in accordance with a predefined treatment protocol. The overall incidence of symptomatic reflex bradycardia was 24.6% (88/358). Univariate analysis revealed the incidence of symptomatic reflex bradycardia in the LG group was significantly lower than that in the OG group [13.0% (13/100) vs. 29.1% (75/258), p = 0.002]. Multivariate logistic regression analysis revealed that the type of surgery (OG vs. LG), advanced age, preoperative bradycardia, type of muscle relaxant (vecuronium vs. rocuronium), no use of intravenous remifentanil, and low core temperature, were independent risk factors for symptomatic reflex bradycardia (odds ratio 3.184; 95% confidence interval 1.490-6.800; p = 0.003). The LG approach was associated with a reduced risk of clinically significant reflex bradycardia compared with the OG approach.

Characterization and antimicrobial activity of sweetpotato starch-based edible film containing origanum (Thymus capitatus) oil.

PubMed

Ehivet, Fabienne E; Min, Byungjin; Park, Mi-Kyung; Oh, Jun-Hyun

2011-01-01

The objectives of this research were to characterize the mechanical and barrier properties of sweetpotato starch (SPS)-based film (SPSF) and to investigate the antimicrobial activity of SPSF containing origanum oil (OG) against foodborne pathogenic bacteria. The SPSF was fabricated with the SPS extracted from commercial sweetpotato roots. Tensile strength (TS), percent elongation at break (E), and water vapor permeability (WVP) were determined to characterize the SPSF fabricated with selected SPS concentrations, plasticizers, and the concentrations of plasticizers. The agar diffusion assay was used to determine the antimicrobial activity of SPSF containing selective concentrations of OG against Salmonella Enteritidis, Escherichia coli O157:H7, and Listeria monocytogenes. The SPSF fabricated with 2.5% SPS exhibited the greatest TS (4.58 MPa). The TS, E, and WVP of SPSF plasticized with 40% sorbitol exhibited 7.96 MPa, 77.92%, 0.212 ng m/m(2) S Pa, respectively. Therefore, the SPSF fabricated with 2.5% SPS and 40% sorbitol was determined as the optimum film. The antimicrobial activity of the SPSF containing OG increased as the concentration of OG increased. And the SPSF containing OG exhibited greater inhibitory effects against the gram-negative bacteria such as S. Enteritidis and E. coli O157:H7 than the gram-positive L. monocytogenes. The greatest antimicrobial activity was observed against S. Enteritidis when the SPSF containing 2% OG was applied, and the maximum square of zone width was 18.43 mm(2).

Increase in Dye:Dendrimer Ratio Decreases Cellular Uptake of Neutral Dendrimers in RAW Cells.

PubMed

Vaidyanathan, Sriram; Kaushik, Milan; Dougherty, Casey; Rattan, Rahul; Goonewardena, Sascha N; Banaszak Holl, Mark M; Monano, Janet; DiMaggio, Stassi

2016-09-12

Neutral generation 3 poly(amidoamine) dendrimers were labeled with Oregon Green 488 (G3-OG n ) to obtain materials with controlled fluorophore:dendrimer ratios (n = 1-2), a mixture containing mostly 3 dyes per dendrimer, a mixture containing primarily 4 or more dyes per dendrimer ( n = 4+), and a stochastic mixture ( n = 4 avg ). The UV absorbance of the dye conjugates increased linearly as n increased and the fluorescence emission decreased linearly as n increased. Cellular uptake was studied in RAW cells and HEK 293A cells as a function of the fluorophore:dendrimer ratio (n). The cellular uptake of G3-OG n ( n = 3, 4+, 4 avg ) into RAW cells was significantly lower than G3-OG n ( n = 1, 2). The uptake of G3-OG n ( n = 3, 4+, 4 avg ) into HEK 293A cells was not significantly different from G3-OG 1 . Thus, the fluorophore:dendrimer ratio was observed to change the extent of uptake in the macrophage uptake mechanism but not in the HEK 293A cell. This difference in endocytosis indicates the presence of a pathway in the macrophage that is sensitive to hydrophobicity of the particle.

Can anti-gravity running improve performance to the same degree as over-ground running?

PubMed

Brennan, Christopher T; Jenkins, David G; Osborne, Mark A; Oyewale, Michael; Kelly, Vincent G

2018-03-11

This study examined the changes in running performance, maximal blood lactate concentrations and running kinematics between 85%BM anti-gravity (AG) running and normal over-ground (OG) running over an 8-week training period. Fifteen elite male developmental cricketers were assigned to either the AG or over-ground (CON) running group. The AG group (n = 7) ran twice a week on an AG treadmill and once per week over-ground. The CON group (n = 8) completed all sessions OG on grass. Both AG and OG training resulted in similar improvements in time trial and shuttle run performance. Maximal running performance showed moderate differences between the groups, however the AG condition resulted in less improvement. Large differences in maximal blood lactate concentrations existed with OG running resulting in greater improvements in blood lactate concentrations measured during maximal running. Moderate increases in stride length paired with moderate decreases in stride rate also resulted from AG training. The use of AG training to supplement regular OG training for performance should be used cautiously, as extended use over long periods of time could lead to altered stride mechanics and reduced blood lactate.

The effect of vision on postural strategies in Prader-Willi patients.

PubMed

Cimolin, Veronica; Galli, Manuela; Vismara, Luca; Grugni, Graziano; Priano, Lorenzo; Capodaglio, Paolo

2011-01-01

The aim of this study was to quantify the role of visual contribution in patients with Prader-Willi syndrome (PWS) on balance maintenance using a force platform. We enrolled 14 individuals with PWS free from conditions associated with impaired balance, 44 obese (OG) and 20 healthy controls (CG). Postural sway was measured for 60s while standing on a force platform (Kistler, CH; acquisition frequency: 500 Hz) integrated with a video system. Patients maintained an upright standing position with Open Eyes (OE) and then with Closed Eyes (CE). The ratio between the value of the parameter under OE and CE conditions was measured. Under OE condition PWS and OG were characterized by higher postural instability than CG, with the PWS group showing poorer balance capacity than OG. The Romberg ratio showed that while OG and CG had lower balance without vision, PWS maintained the same performance changing from OE to CE. The integration of different sensory inputs appears similar in OG and CG with higher postural stability under OE than CE. Balance in PWS is not influenced by the elimination of visual input. Copyright © 2011 Elsevier Ltd. All rights reserved.

Barriers to Breast Cancer Screening among Latinas in the U.S.-Mexico Border Region

DTIC Science & Technology

2011-05-01

la Salud : A breast and cervical... en in g E ve r ha d a m am m og ra m H ad a M am m og ra m w ith in th e la st 2 ye ar s H ad a m am m og ra m w ith in th e la st ye ar U na dj us...Cancer Society, Atlanta, GA 22. Fernandez ME, Gonzales A, Tortolero-Luna G et al (2009) Effectiveness of Cultivando la Salud : a breast and cervical

Self-induced optogalvanic effect in a segmented hollow-cathode discharge

NASA Astrophysics Data System (ADS)

Steflekova, V.; Zhechev, D.

2018-03-01

Optogalvanic (OG) interaction is simulated and studied in a segmented hollow-cathode discharge (SHCD). HCD-lamps are used to induce an OG signal by their own emission or by that of another lamp. The efficiency of the OG of a Ne/Cu HCD lamp in the range 320-380 nm is estimated theoretically. An irregular galvanic peak arising near the inflection point in the i-V curve (∂V/∂i<0) is detected. Its origin is related to Penning ionization of the sputtered cathode material.

VizieR Online Data Catalog: MARVEL analysis of TiO energy levels (McKemmish+, 2017)

NASA Astrophysics Data System (ADS)

McKemmish, L. K.; Masseron, T.; Sheppard, S.; Sandeman, E.; Schofield, Z.; Furtenbacher, T.; Csaszar, A. G.; Tennyson, J.; Sousa-Silva, C.

2017-04-01

48Ti-16OFFNca_33.energies, which contains the relative energies free-floating network incorporating the c1{Phi} v=3 and a1Δ v=3 states, and three directories containing sorted folders and files with predicted transition frequencies using the Marvel energies. (2 data files).

Bright Ideas for Dark Days

ERIC Educational Resources Information Center

Easley, Dauna

2005-01-01

In this brief column, the author of "Teachers Touch Eternity," provides 20 tips that teachers can use to motivate themselves and others through the dark days of winter: (1) Fake it till you make it; (2) Allow for spontaneity; (3) Build an encouragement folder; (4) Lighten up! (5) Read motivational books or inspirational thoughts late at night or…

Photographic copy of photograph (ca. 1934, original print located in ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Photographic copy of photograph (ca. 1934, original print located in Margaret Long Collection, Box 20, Folder 2, Western History Collections, Norlin Library, University of Colorado at Boulder). VIEW OF THE SITE OF BOX ELDER STATION - Box Elder Road, Between 104th & 112th Avenues, Hudson & Watkins Roads, Watkins, Adams County, CO

76 FR 5973 - Privacy Act of 1974; Notice; Publication of the Systems of Records Managed by the Commodity...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-02

...: Paper records are stored in file folders, binders, computer files (eLaw) and computer disks. Electronic records, including computer files, are stored on the Commission's network and other electronic media as... physical security measures. Technical security measures within CFTC include restrictions on computer access...

78 FR 63235 - Tank Vessel Oil Transfers

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-23

... protect the marine environment from oil spilled during oil transfers to or from tank vessels; and what... of your document so that we can contact you if we have questions regarding your submission. To submit... ``Open Docket Folder'' on the line associated with this notice. If you do not have access to the internet...

40 CFR 52.1163 - Additional control measures for East Boston.

Code of Federal Regulations, 2011 CFR

2011-07-01

...”) shall each submit to the Regional Administrator a study or studies of various alternative strategies to... transit service between the Blue Line subway stop and airline terminals at Logan Airport; and (8) Any... information in tickets or folders mailed by airlines using Logan Airport) to publicize the advantages in costs...

40 CFR 52.1163 - Additional control measures for East Boston.

Code of Federal Regulations, 2010 CFR

2010-07-01

...”) shall each submit to the Regional Administrator a study or studies of various alternative strategies to... transit service between the Blue Line subway stop and airline terminals at Logan Airport; and (8) Any... information in tickets or folders mailed by airlines using Logan Airport) to publicize the advantages in costs...

40 CFR 52.1163 - Additional control measures for East Boston.

Code of Federal Regulations, 2014 CFR

2014-07-01

...”) shall each submit to the Regional Administrator a study or studies of various alternative strategies to... transit service between the Blue Line subway stop and airline terminals at Logan Airport; and (8) Any... information in tickets or folders mailed by airlines using Logan Airport) to publicize the advantages in costs...

40 CFR 52.1163 - Additional control measures for East Boston.

Code of Federal Regulations, 2012 CFR

2012-07-01

...”) shall each submit to the Regional Administrator a study or studies of various alternative strategies to... transit service between the Blue Line subway stop and airline terminals at Logan Airport; and (8) Any... information in tickets or folders mailed by airlines using Logan Airport) to publicize the advantages in costs...

40 CFR 52.1163 - Additional control measures for East Boston.

Code of Federal Regulations, 2013 CFR

2013-07-01

...”) shall each submit to the Regional Administrator a study or studies of various alternative strategies to... transit service between the Blue Line subway stop and airline terminals at Logan Airport; and (8) Any... information in tickets or folders mailed by airlines using Logan Airport) to publicize the advantages in costs...

Commercial Contract Training, Navy Area VOTEC Support Center (AVSC) Guidelines

DTIC Science & Technology

1975-06-01

either manual or power operated equipment including collators, folders, paper drills, stitchers and cutters, the student will process printed materials...Challenge, model JF or equal). d. Folding machine, size 17-I1/2 x 22-1/2" (Challenge heavy duty model 175 or equal). e. Stitcher , paper (Bostitch model 7

Environmental Education [30 Instructional Mini-units for K-6].

ERIC Educational Resources Information Center

Minnesota State Dept. of Education, St. Paul.

These 30 self-contained instructional units, for K-6, are structured to promote learning exercises outside the classroom; from the playground, local factory, or city hall to pond, farm, or woodland, places where students may touch the pulse of community life. Attractively packaged in plastic folders, each "mini-unit" provides a teacher's guide…

Haida Story Telling Time with Activity Folder.

ERIC Educational Resources Information Center

Cogo, Robert

One in a series of curriculum materials on Southeast Alaska Natives, this booklet contains seven myths and legends from the Haida oral tradition, each accompanied by discussion questions and suggested learning activities. Intended for use in the intermediate grades, the stories are two to four pages long with many Haida words included in the text…

5 CFR 293.303 - The roles and responsibilities of the Office, agencies, and custodians.

Code of Federal Regulations, 2012 CFR

2012-01-01

... contained within a document management system approved by the Office. (2) A custodian shall be responsible... MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL RECORDS Official Personnel Folder § 293.303 The roles and... such a position is part of the records of the Office of Personnel Management (Office). (b) The Office...

Tlingit Survival Practices and Stories with Activity Folder.

ERIC Educational Resources Information Center

Johnson, Frank

Students learn Tlingit survival practices and lore in this booklet of stories and learning activities. Five readings discuss fire making methods, edible wild foods, weather conditions, and shelter; information is related to the resources of Southeast Alaska and to typical survival situations; e.g., storms at sea and dense fogs. Narratives relate…

Urban Middle School Students' Reflections on Authentic Science Inquiry

ERIC Educational Resources Information Center

Rivera Maulucci, María S.; Brown, Bryan A.; Grey, Salina T.; Sullivan, Shayna

2014-01-01

This study explores the experiences of six urban middle school students in an authentic science inquiry program. Drawing on data including teaching journal entries, student work folders, and semi-structured focus group interviews of six participants, the findings explore six dimensions of authentic science inquiry, an approach to science inquiry…

32 CFR 1639.2 - The claim for Class 2-D.

Code of Federal Regulations, 2011 CFR

2011-07-01

... National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM CLASSIFICATION OF REGISTRANTS PREPARING FOR THE MINISTRY § 1639.2 The claim for Class 2-D. A claim to classification in Class 2-D must be made by the registrant in writing, such document being placed in his file folder. ...

32 CFR 1639.2 - The claim for Class 2-D.

Code of Federal Regulations, 2010 CFR

2010-07-01

... National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM CLASSIFICATION OF REGISTRANTS PREPARING FOR THE MINISTRY § 1639.2 The claim for Class 2-D. A claim to classification in Class 2-D must be made by the registrant in writing, such document being placed in his file folder. ...

Surveying Alumni by Mail: Effect of Booklet/Folder Questionnaire Format and Style of Type on Response Rate.

ERIC Educational Resources Information Center

Boser, Judith A.

1990-01-01

Two investigations, each involving a survey of university alumni, found that questionnaire type font (conventional typewriter type and professional-appearing type) and construction (single pages, stapled, and booklet) did not have a significant effect on response rates. Other considerations that may influence questionnaire design decisions are…

Breast and Gynecologic Cancer | Division of Cancer Prevention

Cancer.gov

[[{"fid":"184","view_mode":"default","fields":{"format":"default","field_file_image_alt_text[und][0][value]":"Breast and Gynecologic Cancer Research Group Homepage Logo","field_file_image_title_text[und][0][value]":"Breast and Gynecologic Cancer Research Group Homepage Logo","field_folder[und]":"15"},"type":"media","attributes":{"alt":"Breast and Gynecologic Cancer Research

Early Detection | Division of Cancer Prevention

Cancer.gov

[[{"fid":"171","view_mode":"default","fields":{"format":"default","field_file_image_alt_text[und][0][value]":"Early Detection Research Group Homepage Logo","field_file_image_title_text[und][0][value]":"Early Detection Research Group Homepage Logo","field_folder[und]":"15"},"type":"media","field_deltas":{"1":{"format":"default","field_file_image_alt_text[und][0][value]":"Early

75 FR 71092 - Privacy Act of 1974; System of Records

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-22

... (DIBRS); 18 U.S.C. 922 note, The Brady Handgun Violence Prevention Act; 28 U.S.C. 534 note, Uniform...: Delete entry and replace with ``Electronic storage media and file folders.'' Retrievability: Delete entry..., The Brady Handgun Violence Prevention Act; 28 U.S.C. 534 note, Uniform Federal Crime Reporting Act; 42...

Community Oncology and Prevention Trials | Division of Cancer Prevention

Cancer.gov

[[{"fid":"168","view_mode":"default","fields":{"format":"default","field_file_image_alt_text[und][0][value]":"Early Detection Research Group Homepage Image","field_file_image_title_text[und][0][value]":"Early Detection Research Group Homepage Image","field_folder[und]":"15"},"type":"media","attributes":{"alt":"Early Detection Research Group Homepage Image","title":"Early

Lung and Upper Aerodigestive Cancer | Division of Cancer Prevention

Cancer.gov

[[{"fid":"180","view_mode":"default","fields":{"format":"default","field_file_image_alt_text[und][0][value]":"Lung and Upper Aerodigestive Cancer Research Group Homepage Logo","field_file_image_title_text[und][0][value]":"Lung and Upper Aerodigestive Cancer Research Group Homepage Logo","field_folder[und]":"15"},"type":"media","attributes":{"alt":"Lung and Upper Aerodigestive

5 CFR 293.303 - The roles and responsibilities of the Office, agencies, and custodians.

Code of Federal Regulations, 2014 CFR

2014-01-01

... contained within a document management system approved by the Office. (2) A custodian shall be responsible... MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL RECORDS Official Personnel Folder § 293.303 The roles and... such a position is part of the records of the Office of Personnel Management (Office). (b) The Office...

48 CFR 304.803-70 - Contract/order file organization and use of checklists.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 4 2013-10-01 2013-10-01 false Contract/order file organization and use of checklists. 304.803-70 Section 304.803-70 Federal Acquisition Regulations System HEALTH... content of HHS contract and order files, OPDIVs shall use the folder filing system and accompanying file...

48 CFR 304.803-70 - Contract/order file organization and use of checklists.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Contract/order file organization and use of checklists. 304.803-70 Section 304.803-70 Federal Acquisition Regulations System HEALTH... content of HHS contract and order files, OPDIVs shall use the folder filing system and accompanying file...

48 CFR 304.803-70 - Contract/order file organization and use of checklists.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Contract/order file organization and use of checklists. 304.803-70 Section 304.803-70 Federal Acquisition Regulations System HEALTH... content of HHS contract and order files, OPDIVs shall use the folder filing system and accompanying file...

48 CFR 304.803-70 - Contract/order file organization and use of checklists.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 4 2012-10-01 2012-10-01 false Contract/order file organization and use of checklists. 304.803-70 Section 304.803-70 Federal Acquisition Regulations System HEALTH... content of HHS contract and order files, OPDIVs shall use the folder filing system and accompanying file...

48 CFR 304.803-70 - Contract/order file organization and use of checklists.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 4 2014-10-01 2014-10-01 false Contract/order file organization and use of checklists. 304.803-70 Section 304.803-70 Federal Acquisition Regulations System HEALTH... content of HHS contract and order files, OPDIVs shall use the folder filing system and accompanying file...

75 FR 1625 - Privacy Act of 1974; Report of Amended or Altered System; Medical, Health and Billing Records System

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-12

...., desktop, laptop, handheld or other computer types) containing protected personal identifiers or PHI is... as the National Indian Women's Resource Center, to conduct analytical and evaluation studies. 8... SYSTEM: STORAGE: File folders, ledgers, card files, microfiche, microfilm, computer tapes, disk packs...

Our World. CEM Topic Folder No. 3.

ERIC Educational Resources Information Center

Undy, Harry

The aim of this pamphlet is to make secondary school students aware of the interdependence of peoples throughout the world and of their own responsibility to the world at large. The pamphlet is written from a Christian and a socioeconomic perspective. The text is arranged into the following broad areas of continuing world problems: the Third…

Windows VPN Set Up | High-Performance Computing | NREL

Science.gov Websites

it in your My Documents folder Configure the client software using that conf file Start the TEXT NEEDED Configure the Client Software Start the Endian Connect App. You'll configure the connection using the hpcvpn-win.conf file, uncheck the "save password" link, and add your UserID. Start

Working Smarter, Not Harder (Part IV).

ERIC Educational Resources Information Center

LaBelle, Sandy

2003-01-01

Discusses ways of improving student attitudes and motivation, such as changing the focus of tests, making students responsible for their work, using a grid to show test results, instituting in-class breaks, using a personal grade book, discussing with students the effects of sleep deprivation, and using separate folders for papers of each class.…

A Note on Using Portfolios To Assess Learning.

ERIC Educational Resources Information Center

Fenwick, Tara J.; Parsons, Jim

1999-01-01

Explains that a portfolio is a collection of student work that reflects the course content and is assembled by the student in a folder or binder over a specified period of time. Discusses how to use portfolios, the benefits of using portfolios as assessment tools, and potential concerns teachers need to address. (CMK)

Nyberg with OGS R&R

NASA Image and Video Library

2013-07-19

ISS036-E-021797 (18 July 2013) --- NASA astronaut Karen Nyberg, Expedition 36 flight engineer, performs a remove and replace of the Oxygen Generation System (OGS) Hydrogen (H2) Sensor in the Tranquility node of the International Space Station.

Pre-treatment of high oil and grease pet food industrial wastewaters using immobilized lipase hydrolyzation.

PubMed

Jeganathan, Jeganaesan; Bassi, Amarjeet; Nakhla, George

2006-09-01

Wastewaters generating from pet food industries contain high concentration of oil and grease (O&G), which is difficult to treat through conventional biological treatment systems. In this study, the hydrolysis of O&G originating from pet food industrial wastewater was evaluated. Candida rugosa lipase was immobilized in calcium alginate beads and applied in the hydrolysis experiment. Results showed that approximately 50% of the O&G was hydrolyzed due to the enzyme activity. A significant increment in COD and VFA production was also observed. The immobilized lipase activity was confirmed with p-nitrophenyl palmitate (pNPP) before and after O&G hydrolysis. During the 3-day experiment, approximately 65% of the beads were recovered and after the hydrolysis, approximately 70% of the enzyme activity remained in the beads. This study shows the potential of immobilized lipase as a pre-treatment step in biological treatment of pet food manufacturing wastewater.

International Space Station United States Orbital Segment Oxygen Generation System On-Orbit Operational Experience

NASA Technical Reports Server (NTRS)

Erickson, Robert J.; Howe, John, Jr.; Kulp, Galen W.; VanKeuren, Steven P.

2008-01-01

The International Space Station (ISS) United States Orbital Segment (USOS) Oxygen Generation System (OGS) was originally intended to be installed in ISS Node 3. The OGS rack delivery was accelerated, and it was launched to ISS in July of 2006 and installed in the US Laboratory Module. Various modification kits were installed to provide its interfaces, and the OGS was first activated in July of 2007 for 15 hours, In October of 2007 it was again activated for 76 hours with varied production rates and day/night cycling. Operational time in each instance was limited by the quantity of feedwater in a Payload Water Reservoir (PWR) bag. Feedwater will be provided by PWR bag until the USOS Water Recovery System (WRS) is delivered to SS in fall of 2008. This paper will discuss operating experience and characteristics of the OGS, as well as operational issues and their resolution.

ogs6 - a new concept for porous-fractured media simulations

NASA Astrophysics Data System (ADS)

Naumov, Dmitri; Bilke, Lars; Fischer, Thomas; Rink, Karsten; Wang, Wenqing; Watanabe, Norihiro; Kolditz, Olaf

2015-04-01

OpenGeoSys (OGS) is a scientific open-source initiative for numerical simulation of thermo-hydro-mechanical/chemical (THMC) processes in porous and fractured media, continuously developed since the mid-eighties. The basic concept is to provide a flexible numerical framework for solving coupled multi-field problems. OGS is targeting mainly on applications in environmental geoscience, e.g. in the fields of contaminant hydrology, water resources management, waste deposits, or geothermal energy systems, but it has also been successfully applied to new topics in energy storage recently. OGS is actively participating several international benchmarking initiatives, e.g. DECOVALEX (waste management), CO2BENCH (CO2 storage and sequestration), SeSBENCH (reactive transport processes) and HM-Intercomp (coupled hydrosystems). Despite the broad applicability of OGS in geo-, hydro- and energy-sciences, several shortcomings became obvious concerning the computational efficiency as well as the code structure became too sophisticated for further efficient development. OGS-5 was designed for object-oriented FEM applications. However, in many multi-field problems a certain flexibility of tailored numerical schemes is essential. Therefore, a new concept was designed to overcome existing bottlenecks. The paradigms for ogs6 are: - Flexibility of numerical schemes (FEM#FVM#FDM), - Computational efficiency (PetaScale ready), - Developer- and user-friendly. ogs6 has a module-oriented architecture based on thematic libraries (e.g. MeshLib, NumLib) on the large scale and uses object-oriented approach for the small scale interfaces. Usage of a linear algebra library (Eigen3) for the mathematical operations together with the ISO C++11 standard increases the expressiveness of the code and makes it more developer-friendly. The new C++ standard also makes the template meta-programming technique code used for compile-time optimizations more compact. We have transitioned the main code development to the GitHub code hosting system (https://github.com/ufz/ogs). The very flexible revision control system Git in combination with issue tracking, developer feedback and the code review options improve the code quality and the development process in general. The continuous testing procedure of the benchmarks as it was established for OGS-5 is maintained. Additionally unit testing, which is automatically triggered by any code changes, is executed by two continuous integration frameworks (Jenkins CI, Travis CI) which build and test the code on different operating systems (Windows, Linux, Mac OS), in multiple configurations and with different compilers (GCC, Clang, Visual Studio). To improve the testing possibilities further, XML based file input formats are introduced helping with automatic validation of the user contributed benchmarks. The first ogs6 prototype version 6.0.1 has been implemented for solving generic elliptic problems. Next steps are envisaged to transient, non-linear and coupled problems. Literature: [1] Kolditz O, Shao H, Wang W, Bauer S (eds) (2014): Thermo-Hydro-Mechanical-Chemical Processes in Fractured Porous Media: Modelling and Benchmarking - Closed Form Solutions. In: Terrestrial Environmental Sciences, Vol. 1, Springer, Heidelberg, ISBN 978-3-319-11893-2, 315pp. http://www.springer.com/earth+sciences+and+geography/geology/book/978-3-319-11893-2 [2] Naumov D (2015): Computational Fluid Dynamics in Unconsolidated Sediments: Model Generation and Discrete Flow Simulations, PhD thesis, Technische Universität Dresden.

Molecular dynamics simulations of pea (Pisum sativum) lectin structure with octyl glucoside detergents: the ligand interactions and dynamics.

PubMed

Konidala, Praveen; Niemeyer, Bernd

2007-07-01

The mitogenic pea (Pisum sativum) lectin is a legume protein of non-immunoglobulin nature capable of specific recognition of glucose derivatives without altering its structure. Molecular dynamics simulations were performed in a realistic environment to investigate the structure and interaction properties of pea lectin with various concentrations of n-octyl-beta-d-glucopyranoside (OG) detergent monomers distributed inside explicit solvent cell. In addition, the diffusion coefficients of the ligands (OG, Ca2+, Mn2+, and Cl-) and the water molecules were also reported. The structural flexibility of the lectin was conserved in all simulations. The self-assembly of OG monomers into a small micelle at the hydrophobic site of the lectin was noticed in the simulation with 20 OG monomers. The interaction energy analysis concludes that the lectin was appropriately termed an adaptive structure. One or rarely two binding sites were observed at an instant in each simulation that were electrostatically favoured for the OG to interact with the surface amino acid residues. Enhanced binding of OG to the pea lectin was quantified in the system containing only Ca2+ divalent ions. Interestingly, no binding was observed in the simulation without divalent ions. Furthermore, the lectin-ligand complex was stabilized by multiple hydrogen bonds and at least one water bridge. Finally, the work was also in accordance with the published work elsewhere that the simulations performed with different initial conditions and using higher nonbonded cutoffs for the van der Waals and electrostatic interactions provide more accurate information and clues than the single large simulation of the biomolecular system of interest.

Hypercaloric Diet Establishes Erectile Dysfunction in Rat: Mechanisms Underlying the Endothelial Damage

PubMed Central

de Souza, Iara L. L.; Barros, Bárbara C.; de Oliveira, Giuliana A.; Queiroga, Fernando R.; Toscano, Lydiane T.; Silva, Alexandre S.; Silva, Patrícia M.; Interaminense, Leylliane F. L.; Cavalcante, Fabiana de Andrade; da Silva, Bagnólia A.

2017-01-01

Obesity is characterized by an excessive increase in body mass, leading to endothelial damage that may favor the development of erectile dysfunction (ED). ED is defined as the inability to achieve or maintain a penile erection long enough to have a sexual intercourse. In this context, different ED models were developed, however the high price of special animals or the long period to establish the disease has limited studies in this field. Therefore, this study proposed to establish and characterize a novel model of ED in rats associated to a hypercaloric diet consumption. Animals were randomly divided into control group (CG), which received a standard diet, and obese group (OG), fed with a hypercaloric diet during 8 weeks. Rat's erectile function was evaluated in vivo and in vitro. Food and caloric intake of OG were reduced compared to CG, due to an increased diet energy efficiency. However, OG presented an increased body mass, inguinal, retroperitoneal and epididymal adipose tissues, as well as body adiposity index at the end of experimental protocol. In erectile function analysis, there was a decrease in the number and the latency of penile erections in OG. Additionally, the contractile reactivity of corpus cavernosum was increased in OG, favoring penile detumescence and related to a reduced nitric oxide bioavailability and an increased in contractile prostaglandins levels as a consequence of endothelial damage. Moreover, the endothelium-relaxation reactivity of corpus cavernosum was attenuated in OG associated to the oxidative stress. Thus, it was provided a model for advances in sexual dysfunction field and drug discovery for ED treatment. PMID:29085300

Prescribing of asthma drugs for children 2004-2015.

PubMed

Mikalsen, Ingvild Bruun; Karlstad, Øystein; Furu, Kari; Øymar, Knut

2018-02-20

Astma kan være vanskelig å diagnostisere hos barn. For barn under skolealder finnes det få tilgjengelige objektive diagnostiske undersøkelser, og retningslinjene for diagnose og behandling er basert på sykehistorie og klinisk undersøkelse. Dette kan gi rom for varierende behandlingspraksis. Data fra Reseptregisteret ble brukt til å studere forskrivning av legemidler mot astma til barn i aldersgruppene 0-4 år og 5-9 år fordelt på fylker fra 2004-15. Det var stor variasjon mellom fylkene i andelen per 1 000 barn som fikk forskrevet legemidler mot astma i perioden 2012-14 (aldersgruppen 0-4 år: median: 104/1 000; ekstremverdier: 64-147, aldersgruppen 5-9 år: 68/1000; 46-86). Inhalasjonssteroider var hyppigst forskrevet, og det var her variasjonen mellom fylkene var størst i begge aldersgruppene (aldersgruppen 0-4 år: 85/1 000; 42-116, aldersgruppen 5-9 år: 51/1 000; 31-70). De fleste fikk kun en eller få forskrivninger med inhalasjonssteroider over en treårsperiode. Endring i forskrivningen av inhalasjonssteroider fra 2004 til 2015 varierte betydelig mellom fylkene, mest for aldersgruppen 0-4 år. Stor forskjell i forskrivning av legemidler mot astma fylkene imellom, høy andel sporadisk bruk og endring over tid, særlig i den yngste aldersgruppen, kan tyde på en unaturlig variasjon i behandlingen som ikke kan forklares av forskjeller i astmaforekomst. Uklare retningslinjer som ikke er tilstrekkelig innarbeidet i klinisk praksis kan være én årsak.

SU-E-J-129: A Strategy to Consolidate the Image Database of a VERO Unit Into a Radiotherapy Management System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yan, Y; Medin, P; Yordy, J

2014-06-01

Purpose: To present a strategy to integrate the imaging database of a VERO unit with a treatment management system (TMS) to improve clinical workflow and consolidate image data to facilitate clinical quality control and documentation. Methods: A VERO unit is equipped with both kV and MV imaging capabilities for IGRT treatments. It has its own imaging database behind a firewall. It has been a challenge to transfer images on this unit to a TMS in a radiation therapy clinic so that registered images can be reviewed remotely with an approval or rejection record. In this study, a software system, iPump-VERO,more » was developed to connect VERO and a TMS in our clinic. The patient database folder on the VERO unit was mapped to a read-only folder on a file server outside VERO firewall. The application runs on a regular computer with the read access to the patient database folder. It finds the latest registered images and fuses them in one of six predefined patterns before sends them via DICOM connection to the TMS. The residual image registration errors will be overlaid on the fused image to facilitate image review. Results: The fused images of either registered kV planar images or CBCT images are fully DICOM compatible. A sentinel module is built to sense new registered images with negligible computing resources from the VERO ExacTrac imaging computer. It takes a few seconds to fuse registered images and send them to the TMS. The whole process is automated without any human intervention. Conclusion: Transferring images in DICOM connection is the easiest way to consolidate images of various sources in your TMS. Technically the attending does not have to go to the VERO treatment console to review image registration prior delivery. It is a useful tool for a busy clinic with a VERO unit.« less

Personal computer wallpaper user segmentation based on Sasang typology.

PubMed

Lee, Joung-Youn

2015-03-01

As human-computer interaction (HCI) is becoming a significant part of all human life, the user's emotional satisfaction is an important factor to consider. These changes have been pointed out by several researchers who claim that a user's personality may become the most important factor in the design. The objective of this study is to examine Sasang typology as a user segmentation method in the area of HCI design. To test HCI usage patterns in terms of the user's personality and temperament, this study focuses on personal computer (PC) or lap-top wallpaper settings. One hundred and four Facebook friends completed a QSCC II survey assessing Sasang typology type and sent a captured image of their personal PC or lap-top wallpaper. To classify the computer usage pattern, folder organization and wallpaper setting were investigated. The research showed that So-Yang type organized folders and icons in an orderly manner, whereas So-Eum type did not organize folders and icons at all. With regard to wallpaper settings, So-Yang type used the default wallpaper provided by the PC but So-Eum type used landscape images. Because So-Yang type was reported to be emotionally stable and extrovert, they tended to be highly concerned with online privacy compared with So-Eum type. So-Eum type use a lot of images of landscapes as the background image, which demonstrates So-Eum's low emotional stability, anxiety, and the desire to obtain analogy throughout the computer screen. Also, So-Yang's wallpapers display family or peripheral figures and this is due to the sociability that extrovert So-Yang types possess. By proposing the Sasang typology as a factor in influencing an HCI usage pattern in this study, it can be used to predict the user's HCI experience, or suggest a native design methodology that can actively cope with the user's psychological environment.

Magnetic EDTA functionalized CoFe2O4 nanoparticles (EDTA-CoFe2O4) as a novel catalyst for peroxymonosulfate activation and degradation of Orange G.

PubMed

Deng, Lin; Shi, Zhou; Zou, Zhiyan; Zhou, Shiqing

2017-04-01

EDTA functionalized CoFe 2 O 4 nanoparticles (EDTA-CoFe 2 O 4 ) synthesized using a facile one-pot solvothermal method were employed as catalysts to activate peroxymonosulfate (PMS) with Orange G (OG) as the target pollutant. Effects of operating parameters including initial solution pH, catalyst dosage, PMS dosage, and water matrix components such as Cl - , NO 3 - , CO 3 2- , and humic acid were evaluated. A degradation efficiency of 93% was achieved in 15 min with 1 mM PMS and 0.2 g/L EDTA-CoFe 2 O 4 catalyst, while only 57% of OG was degraded within 15 min in CoFe 2 O 4 /PMS system. The degradation of OG followed pseudo-first-order kinetics, and the apparent first-order date constant (k obs ) for OG in EDTA-CoFe 2 O 4 /PMS and CoFe 2 O 4 /PMS system was determined to be 0.152 and 0.077 min -1 , respectively. OG degradation by EDTA-CoFe 2 O 4 /PMS was enhanced with the increase of catalyst and PMS doses at respective range of 0.1-2.0 g/L and 0.5-10.0 mM. Higher efficiency of OG oxidation was observed within a wide pH range (3.0-9.0), implying the possibility of applying EDTA-CoFe 2 O 4 /PMS process under environmental realistic conditions. Humic acid (HA) at low concentration accelerated the removal of OG; however, a less apparent inhibitive effect was observed at HA addition of 10 mg/L. The k obs value was found to decrease slightly from 0.1601 to 0.1274, 0.1248, and 0.1152 min -1 with the addition of NO 3 - , CO 3 2- , and Cl - , respectively, but near-complete removal of OG could still be obtained after 15 min. Both of the sulfate radicals and hydroxyl radicals were produced in the reaction, and sulfate radicals were the dominant according to the scavenging tests and electron paramagnetic resonance (EPR) tests. Finally, a degradation mechanism was proposed, and the stability and reusability of the EDTA-CoFe 2 O 4 were evaluated.

40 CFR 432.25 - New source performance standards (NSPS).

Code of Federal Regulations, 2010 CFR

2010-07-01

..., fecal coliform, O&G, and TSS are the same as the limitations specified in § 432.22(a)(1), and the... on-site, the standards for BOD5, fecal coliform, O&G, and TSS are the same as the corresponding...

40 CFR 432.85 - New source performance standards (NSPS).

Code of Federal Regulations, 2011 CFR

2011-07-01

..., fecal coliform, O&G, and TSS specified in § 432.82(a). (b) Facilities that generate more than 50 million pounds per year of finished products must achieve the limitations for BOD5, fecal coliform, O&G, and TSS...

40 CFR 432.35 - New source performance standards (NSPS).

Code of Federal Regulations, 2011 CFR

2011-07-01

..., fecal coliform, TSS, and O&G are the same as the limitations specified in § 432.32(a)(1) and the... on-site, the standards for BOD5, fecal coliform, TSS, and O&G are the same as the corresponding...

40 CFR 432.65 - New source performance standards (NSPS).

Code of Federal Regulations, 2011 CFR

2011-07-01

..., fecal coliform, O&G, and TSS specified in § 432.62(a). (b) Facilities that generate more than 50 million pounds per year of finished products must achieve the limitations for BOD5, fecal coliform, O&G, and TSS...

40 CFR 432.35 - New source performance standards (NSPS).

Code of Federal Regulations, 2010 CFR

2010-07-01

..., fecal coliform, TSS, and O&G are the same as the limitations specified in § 432.32(a)(1) and the... on-site, the standards for BOD5, fecal coliform, TSS, and O&G are the same as the corresponding...

40 CFR 432.45 - New source performance standards (NSPS).

Code of Federal Regulations, 2010 CFR

2010-07-01

..., fecal coliform, TSS, and O&G are the same as the limitations specified in § 432.42(a)(1); and standards... on-site, the standards for BOD5, fecal coliform, TSS, and O&G are the same as the limitations...

40 CFR 432.15 - New source performance standards (NSPS).

Code of Federal Regulations, 2011 CFR

2011-07-01

..., fecal coliform, O&G, and TSS are the same as the corresponding limitations specified in § 432.12(a)(1... on-site, the standards for BOD5, fecal coliform, O&G, and TSS are the same as the limitations...

40 CFR 432.25 - New source performance standards (NSPS).

Code of Federal Regulations, 2011 CFR

2011-07-01

..., fecal coliform, O&G, and TSS are the same as the limitations specified in § 432.22(a)(1), and the... on-site, the standards for BOD5, fecal coliform, O&G, and TSS are the same as the corresponding...

40 CFR 432.85 - New source performance standards (NSPS).

Code of Federal Regulations, 2010 CFR

2010-07-01

..., fecal coliform, O&G, and TSS specified in § 432.82(a). (b) Facilities that generate more than 50 million pounds per year of finished products must achieve the limitations for BOD5, fecal coliform, O&G, and TSS...

40 CFR 432.15 - New source performance standards (NSPS).

Code of Federal Regulations, 2010 CFR

2010-07-01

..., fecal coliform, O&G, and TSS are the same as the corresponding limitations specified in § 432.12(a)(1... on-site, the standards for BOD5, fecal coliform, O&G, and TSS are the same as the limitations...

40 CFR 432.45 - New source performance standards (NSPS).

Code of Federal Regulations, 2011 CFR

2011-07-01

..., fecal coliform, TSS, and O&G are the same as the limitations specified in § 432.42(a)(1); and standards... on-site, the standards for BOD5, fecal coliform, TSS, and O&G are the same as the limitations...

Watershed-Scale Impacts from Surface Water Disposal of Oil and Gas Wastewater in Western Pennsylvania.

PubMed

Burgos, William D; Castillo-Meza, Luis; Tasker, Travis L; Geeza, Thomas J; Drohan, Patrick J; Liu, Xiaofeng; Landis, Joshua D; Blotevogel, Jens; McLaughlin, Molly; Borch, Thomas; Warner, Nathaniel R

2017-08-01

Combining horizontal drilling with high volume hydraulic fracturing has increased extraction of hydrocarbons from low-permeability oil and gas (O&G) formations across the United States; accompanied by increased wastewater production. Surface water discharges of O&G wastewater by centralized waste treatment (CWT) plants pose risks to aquatic and human health. We evaluated the impact of surface water disposal of O&G wastewater from CWT plants upstream of the Conemaugh River Lake (dam controlled reservoir) in western Pennsylvania. Regulatory compliance data were collected to calculate annual contaminant loads (Ba, Cl, total dissolved solids (TDS)) to document historical industrial activity. In this study, two CWT plants 10 and 19 km upstream of a reservoir left geochemical signatures in sediments and porewaters corresponding to peak industrial activity that occurred 5 to 10 years earlier. Sediment cores were sectioned for the collection of paired samples of sediment and porewater, and analyzed for analytes to identify unconventional O&G wastewater disposal. Sediment layers corresponding to the years of maximum O&G wastewater disposal contained higher concentrations of salts, alkaline earth metals, and organic chemicals. Isotopic ratios of 226 Ra /228 Ra and 87 Sr /86 Sr identified that peak concentrations of Ra and Sr were likely sourced from wastewaters that originated from the Marcellus Shale formation.

Spatiotemporal Industrial Activity Model for Estimating the Intensity of Oil and Gas Operations in Colorado.

PubMed

Allshouse, William B; Adgate, John L; Blair, Benjamin D; McKenzie, Lisa M

2017-09-05

Oil and gas (O&G) production in the United States has increased in the last 15 years, and operations, which are trending toward large multiwell pads, release hazardous air pollutants. Health studies have relied on proximity to O&G wells as an exposure metric, typically using an inverse distance-weighting (IDW) approach. Because O&G emissions are dependent on multiple factors, a dynamic model is needed to describe the variability in air pollution emissions over space and time. We used information on Colorado O&G activities, production volumes, and air pollutant emission rates from two Colorado basins to create a spatiotemporal industrial activity model to develop an intensity-adjusted IDW well-count metric. The Spearman correlation coefficient between this metric and measured pollutant concentrations was 0.74. We applied our model to households in Greeley, Colorado, which is in the middle of the densely developed Denver-Julesburg basin. Our intensity-adjusted IDW increased the unadjusted IDW dynamic range by a factor of 19 and distinguishes high-intensity events, such as hydraulic fracturing and flowback, from lower-intensity events, such as production at single-well pads. As the frequency of multiwell pads increases, it will become increasingly important to characterize the range of intensities at O&G sites when conducting epidemiological studies.

An overview of turbomachinery project in Malaysian oil and gas industry

NASA Astrophysics Data System (ADS)

Abd. Rahman Sabri, Harris; Rahim, Abd. Rahman Abdul; Yew, Wong Kuan; Ismail, Syuhaida

2017-12-01

Being the most demanding, challenging and exciting engineering and technological advances has provided escalated interests amongst the engineers at large to venture into the oil and gas (O&G) industry. Although claimed as the most expensive industry in the world via the utilisation of critical equipments, the O&G industry is still recording notorius failures in its project management especially due to turbomachinery issues, the heart equipment of any O&G project. Therefore, it is important for this paper to review turbomachinery project as one of the long lead items during project executions that is also proven to be the most costly and expensive equipment. This paper therefore discusses the gaps in turbomachinery studies via literature review in highlighting its application in O&G projects. It is found that the main components of turbomachinery are driver and driven equipment, which are applied for mechanical equipment, Electric Power Generation and heat generation for Combined Cycled Configuration. Important variables for turbomachinery selection include: (1) process requirement; (2) site location; (3) driver selection; (4) equipment sparing philosophy; (5) efficiency and reliability; (6) operability and maintainability; and (7) cost. It is hoped that this paper would lead to the successful project management of turbomachinery in the O&G industry.

Assessment of the Efficacy of Home Remedial Methods to Improve Drinking Water Quality in Two Major Aquifer Systems in Jaffna Peninsula, Sri Lanka

PubMed Central

Subanky, Suvendran

2017-01-01

Chunnakam and Vadamaradchi are two major aquifer systems in Jaffna Peninsula, Sri Lanka. This study was performed to compare water quality in the domestic wells in these aquifers and to assess the efficacy of household water treatments for treating contaminated water. Replicate well water samples were collected from each aquifer and pH, dissolved oxygen (DO), conductivity, total dissolved solids (TDS), salinity, temperature, total solids (TS), total hardness (TH), chemical oxygen demand (COD), oil and grease (OG), nitrate N (N), and total phosphate (TP) were measured. The sampled water from the domestic wells was filtered through commercial mineral filter and Moringa oleifera leaf powder and boiled at 100°C for 10 minutes and the TH, OG, N, and TP were measured. Both OG and N in Chunnakam were significantly higher and the DO were significantly lower than those of Vadamaradchi. TH, N, and OG of some wells exceeded the drinking water quality standards established by Sri Lanka Standards Institution. Moringa oleifera leaf powder filtration reduced N significantly and filtering through commercial mineral filter reduced OG, TH, and N significantly. Boiling at 100°C could remove TH significantly but may cause significant increase in N which might result in health impacts. PMID:29181225

Assessment of the Efficacy of Home Remedial Methods to Improve Drinking Water Quality in Two Major Aquifer Systems in Jaffna Peninsula, Sri Lanka.

PubMed

Wijeyaratne, W M Dimuthu Nilmini; Subanky, Suvendran

2017-01-01

Chunnakam and Vadamaradchi are two major aquifer systems in Jaffna Peninsula, Sri Lanka. This study was performed to compare water quality in the domestic wells in these aquifers and to assess the efficacy of household water treatments for treating contaminated water. Replicate well water samples were collected from each aquifer and pH, dissolved oxygen (DO), conductivity, total dissolved solids (TDS), salinity, temperature, total solids (TS), total hardness (TH), chemical oxygen demand (COD), oil and grease (OG), nitrate N (N), and total phosphate (TP) were measured. The sampled water from the domestic wells was filtered through commercial mineral filter and Moringa oleifera leaf powder and boiled at 100°C for 10 minutes and the TH, OG, N, and TP were measured. Both OG and N in Chunnakam were significantly higher and the DO were significantly lower than those of Vadamaradchi. TH, N, and OG of some wells exceeded the drinking water quality standards established by Sri Lanka Standards Institution. Moringa oleifera leaf powder filtration reduced N significantly and filtering through commercial mineral filter reduced OG, TH, and N significantly. Boiling at 100°C could remove TH significantly but may cause significant increase in N which might result in health impacts.

READIT! A Text Presentation Application for the Macintosh

DTIC Science & Technology

1988-12-28

remaining passages would all look similar to the one shown here.) In this example, the subject’s number (7) was the basis for the output folder name: * sub7 ...before,1 segment = 1 sentence. THE FOLLOWING OUTPUT IS FOR SUBJECT " sub7 ." TIMES ARE IN VIEWING ORDER... #W => Number of Words. #L=> Number of Letters

Water Worlds. 4-H Member's Guide M-5-18; 4-H Leaders Guide L-5-18.

ERIC Educational Resources Information Center

Hawkes, Janet E.; And Others

This pocket folder of materials is designed to provide children aged 9 to 12 with an opportunity to explore and observe aquatic environments. The package includes a 4-H Leader's guide, member's guide, and supplementary materials. The leader's guide contains safety considerations, tips and techniques, and additional activities for getting started…

Personal Privacy in an Information Society: What are the Trade-Offs? Insights into Consumer Issues.

ERIC Educational Resources Information Center

J.C. Penney Co., Inc., New York, NY.

Insights into Consumer Issues is one of a group of educational publications and teaching units that J.C. Penney provides for consumer educators as a public service. This folder illustrates that although computerized processing of personal information has brought considerable convenience, the potential risk to personal privacy is of increasing…

TideGen LCOE Workbooks

DOE Data Explorer

Jarlath McEntee

2016-03-21

Workbooks showing Annualized Energy Production, Cost Breakdown Structure, Levelized Cost of Electricity for DOE Refernce Tidal Project 1) Baseline TidGen Power System 2) TidGen Power System with the application of Advanced Controls 3) Advanced TidGen Power System with several enhancements These files are provided as a zipped set. Files are linked together and must be viewed in the same folder.

77 FR 35266 - Special Local Regulation for Marine Events, Chesapeake Bay Workboat Race, Back River, Messick...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-13

... necessary to protect life, property and the environment during the workboat race event; therefore, a 30-day....'' Click on Open Docket Folder on the line associated with this rulemaking. You may also visit the Docket..., except Federal holidays. FOR FURTHER INFORMATION CONTACT: If you have questions on this rule, call or...

20 CFR 404.617 - Pilot program for photographic identification of disability benefit applicants in designated...

Code of Federal Regulations, 2010 CFR

2010-04-01

... of Applications and Other Forms Applications § 404.617 Pilot program for photographic identification... the pilot, you or a person acting on your behalf must give SSA permission to take your photograph and make this photograph a part of the claims folder. You must give us this permission when you apply for...

Data Science Bowl Launched to Improve Lung Cancer Screening | Division of Cancer Prevention

Cancer.gov

[[{"fid":"2078","view_mode":"default","fields":{"format":"default","field_file_image_alt_text[und][0][value]":"Data Science Bowl Logo","field_file_image_title_text[und][0][value]":"Data Science Bowl Logo","field_folder[und]":"76"},"type":"media","field_deltas":{"1":{"format":"default","field_file_image_alt_text[und][0][value]":"Data Science Bowl

76 FR 68203 - Mechanisms of Compliance with United States Citizenship Requirements for the Ownership of Vessels...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-03

... Transportation, West Building Ground Floor, Room W12-140, 1200 New Jersey Avenue SE., Washington, DC 20590-0001... or privileged or confidential information, or be detrimental to the security of transportation. The... the ``Open Docket Folder'' in the ``Actions'' column. If you do not have access to the internet, you...

Can the Integration of a PLE in an E-Portfolio Platform Improve Generic Competences?

ERIC Educational Resources Information Center

Galván-Fernández, Cristina; Rubio-Hurtado, María José; Martínez-Olmo, Francesc; Rodríguez-Illera, José Luis

2017-01-01

The study analyzes the improvement in generic competences through e-portfolio/PLE platform and didactic planning. The new version of the platform, Digital Folder, contains utilities for students and teachers and some PLE components that help the learning process through e-portfolios. Didactic planning is compared for students from the University…

Pop-Up Constructions Motivate and Reinforce Science Learning for Upper Elementary Students

ERIC Educational Resources Information Center

Olsen, Benjamin D.; Zhbanova, Ksenia S.; Parpucu, Harun; Alkouri, Zaid; Rule, Audrey C.

2013-01-01

Pop-up boxes and folder constructions support student inquiry while integrating art, craft, spatial, and creativity skills. Step-by-step illustrated directions for constructing pop-up boxes are provided with example images of pop-up boxes focused on ecological issues. Teachers used these pop-up constructions to assist fourth- and fifth-grade…

OGS Maintenance

NASA Image and Video Library

2010-07-21

ISS024-E-009246 (21 July 2010) --- NASA astronaut Tracy Caldwell Dyson, Expedition 24 flight engineer, is pictured during troubleshooting operations of the Oxygen Generator System (OGS) hardware and replacement of an H2 (hydrogen) Dome Orbit Replaceable Unit (ORU) in the Destiny laboratory of the International Space Station.

40 CFR 432.75 - New source performance standards (NSPS).

Code of Federal Regulations, 2011 CFR

2011-07-01

... achieve the standards for BOD5, fecal coliform, O&G, and TSS specified in § 432.72(a). (b) Facilities that..., fecal coliform, O&G, and TSS specified in § 432.72(b) and the limitations for ammonia (as N) and total...

40 CFR 432.95 - New source performance standards (NSPS).

Code of Federal Regulations, 2011 CFR

2011-07-01

... standards for BOD 5, fecal coliform, O&G, and TSS specified in § 432.92(a). (b) Facilities that generate... coliform, O&G, and TSS specified in § 432.92(b) and the limitations for ammonia (as N) and total nitrogen...

Surface texture of resin-modified glass ionomer cements: effects of finishing/polishing systems.

PubMed

Yap, Adrian U J; Tan, W S; Yeo, J C; Yap, W Y; Ong, S B

2002-01-01

This study investigated the surface texture of two resin-modified glass ionomer cements (RMGICs) in the vertical and horizontal axis after treatment with different finishing/polishing systems. Class V preparations were made on the buccal and lingual/palatal surfaces of freshly extracted teeth. The cavities on each tooth were restored with Fuji II LC (GC) and Photac-Fil Quick (ESPE) according to manufacturers' instructions. Immediately after light-polymerization, gross finishing was done with 8-flute tungsten carbide burs. The teeth were then randomly divided into four groups and finished/polished with (a) Robot Carbides (RC); (b) Super-Snap system (SS); (c) OneGloss (OG) and (d) CompoSite Points (CS). The sample size for each material-finishing/polishing system combination was eight. The mean surface roughness (microm) in vertical (RaV) and horizontal (RaH) axis was measured using a profilometer. Data was subjected to ANOVA/Scheffe's tests and Independent Samples t-test at significance level 0.05. Mean RaV ranged from 0.59-1.31 and 0.83-1.52, while mean RaH ranged from 0.80-1.43 and 0.85-1.58 for Fuji II LC and Photac-Fil, respectively. Results of statistical analysis were as follows: Fuji II LC: RaV-RC, SS

Effects of finishing/polishing techniques on microleakage of resin-modified glass ilonomer cement restorations.

PubMed

Yap, Adrian U J; Yap, W Y; Yeo, Egwin J C; Tan, Jane W S; Ong, Debbie S B

2003-01-01

This study investigated the effect of finishing/polishing techniques on the microleakage of resin-modified glass ionomer restorations. Class V preparations were made on the buccal and lingual/palatal surfaces of freshly extracted teeth. The cavities on each tooth were restored with Fuji II LC (FT [GC]) and Photac-Fil Quick (PF [3M-ESPE]) according to manufacturers' instructions. Immediately after light-polymerization, gross finishing was done with eight-fluted tungsten carbide burs. The teeth were then randomly divided into four groups and finishing/polishing was done with one of the following systems: (a) Robot Carbides (RC); (b) Super-Snap system (SS); (c) OneGloss (OG) and (d) CompoSite Polishers (CS). The sample size for each material-finishing/polishing system combination was eight. After finishing/polishing, the teeth were stored in distilled water at 37 degrees C for one week. The root apices were then sealed with acrylic and two coats of varnish was applied 1 mm beyond the restoration margins. The teeth were subsequently subjected to dye penetration testing (0.5% basic fuchsin), sectioned and scored. Data was analyzed using Kruskal-Wallis and Mann-Whitney U tests at a significance level of 0.05. Results of statistical analysis were as follows: Enamel margins: PF-OG

Anti-Cancer Efficacy of Silybin Derivatives - A Structure-Activity Relationship

PubMed Central

Agarwal, Chapla; Wadhwa, Ritambhara; Deep, Gagan; Biedermann, David; Gažák, Radek; Křen, Vladimír; Agarwal, Rajesh

2013-01-01

Silybin or silibinin, a flavonolignan isolated from Milk thistle seeds, is one of the popular dietary supplements and has been extensively studied for its antioxidant, hepatoprotective and anti-cancer properties. We have envisioned that potency of silybin could be further enhanced through suitable modification/s in its chemical structure. Accordingly, here, we synthesized and characterized a series of silybin derivatives namely 2,3-dehydrosilybin (DHS), 7-O-methylsilybin (7OM), 7-O-galloylsilybin (7OG), 7,23-disulphatesilybin (DSS), 7-O-palmitoylsilybin (7OP), and 23-O-palmitoylsilybin (23OP); and compared their anti-cancer efficacy using human bladder cancer HTB9, colon cancer HCT116 and prostate carcinoma PC3 cells. In all the 3 cell lines, DHS, 7OM and 7OG demonstrated better growth inhibitory effects and compared to silybin, while other silybin derivatives showed lesser or no efficacy. Next, we prepared the optical isomers (A and B) of silybin, DHS, 7OM and 7OG, and compared their anti-cancer efficacy. Isomers of these three silybin derivatives also showed better efficacy compared with respective silybin isomers, but in each, there was no clear cut silybin A versus B isomer activity preference. Further studies in HTB cells found that DHS, 7OM and 7OG exert better apoptotic activity than silibinin. Clonogenic assays in HTB9 cells further confirmed that both the racemic mixtures as well as pure optical isomers of DHS, 7OM and 7OG were more effective than silybin. Overall, these results clearly suggest that the anti-cancer efficacy of silybin could be significantly enhanced through structural modifications, and identify strong anti-cancer efficacy of silybin derivatives, namely DHS, 7OM, and 7OG, signifying that their efficacy and toxicity should be evaluated in relevant pre-clinical cancer models in rodents. PMID:23555889

Postoperative Outcomes of Minimally Invasive Gastrectomy Versus Open Gastrectomy During the Early Introduction of Minimally Invasive Gastrectomy in the Netherlands: A Population-based Cohort Study.

PubMed

Brenkman, Hylke J F; Gisbertz, Suzanne S; Slaman, Annelijn E; Goense, Lucas; Ruurda, Jelle P; van Berge Henegouwen, Mark I; van Hillegersberg, Richard

2017-11-01

To compare postoperative outcomes of minimally invasive gastrectomy (MIG) to open gastrectomy (OG) for cancer during the introduction of MIG in the Netherlands. Between 2011 and 2015, the use of MIG increased from 4% to 53% in the Netherlands. This population-based cohort study included all patients with curable gastric adenocarcinoma that underwent gastrectomy between 2011 and 2015, registered in the Dutch Upper GI Cancer Audit. Patients with missing preoperative data, and patients in whom no lymphadenectomy or reconstruction was performed were excluded. Propensity score matching was applied to create comparable groups between patients receiving MIG or OG, using year of surgery and other potential confounders. Morbidity, mortality, and hospital stay were evaluated. Of the 1697 eligible patients, 813 were discarded after propensity score matching; 442 and 442 patients who underwent MIG and OG, respectively, remained. Conversions occurred in 10% of the patients during MIG. Although the overall postoperative morbidity (37% vs 40%, P = 0.489) and mortality rates (6% vs 4%, P = 0.214) were comparable between the 2 groups, patients who underwent MIG experienced less wound complications (2% vs 5%, P = 0.006). Anastomotic leakage occurred in 8% of the patients after MIG, and in 7% after OG (P = 0.525). The median hospital stay declined over the years for both procedures (11 to 8 days, P < 0.001). Overall, hospital stay was shorter after MIG compared with OG (8 vs 10 days, P < 0.001). MIG was safely introduced in the Netherlands, with overall morbidity and mortality comparable with OG, less wound complications and shorter hospitalization.

Resterilized mesh in repair of abdominal wall defects in rats.

PubMed

Sucullu, Ilker; Akin, Mehmet Levhi; Yitgin, Selahattin; Filiz, Ali Ilker; Kurt, Yavuz

2008-01-01

A variety of negative opinions about repeated usage of relatively expensive resterilized synthetic meshes have been considered. It had been stated that resterilized polypropylene meshes inhibits fibroblastic activity, decreases proliferative activity, and increases apoptosis in human fibroblast culture, in vitro. The purpose of this study is the in vivo evaluation of the resterilized mesh repairs of abdominal hernia defects in rat models of incisional hernia by comparing primer repair and original mesh repairs. The rats (n = 22) were separated into three groups. While the abdominal defect was repaired by primary suture in the control group (CG), the defects were repaired by original mesh (OG) or resterilized mesh (RG) in mesh-repaired groups. After 21 days, the rats were evaluated for tissue tensile strengths, tissue hydroxyproline levels, tissue inflammation, fibrosis, and apoptosis. Although the tensile strengths in OG and RG were significantly higher than those of CG (p < .05 and p < .05), there was no significant difference between two groups. The tissue hydroxyproline levels in OG and RG were also higher than those of CG. The difference was not significant between the two groups. The inflammation and fibrosis indexes in OG and RG were significantly higher than those of CG (p < .0001 for both), but there was no difference between groups. While the apoptosis index in OG and RG was also higher than that of CG (p < .0001 for both), there was no significant difference between OG and RG. The usage of resterilized mesh in abdominal wall repair did not reduce the tissue tensile strength, did not affect the tissue hydroxyproline levels, did not decrease the fibrosis, and did not increase the tissue inflammation and apoptosis. In conclusion, usage of resterilized meshes in abdominal wall defects was as safe as sterilized meshes.

An Acidic PATHOGENESIS-RELATED1 Gene of Oryza grandiglumis is Involved in Disease Resistance Response Against Bacterial Infection

PubMed Central

Shin, Sang Hyun; Pak, Jung-Hun; Kim, Mi Jin; Kim, Hye Jeong; Oh, Ju Sung; Choi, Hong Kyu; Jung, Ho Won; Chung, Young Soo

2014-01-01

Wild rice, Oryza grandiglumis shows hyper-resistance response to pathogen infection. In order to identify genes necessary for defense response in plants, we have carried out a subtractive hybridization coupled with a cDNA macroarray. An acidic PATHOGENESIS-RELATED1 (PR1) gene of the wild rice is highly identical to the acidic PR1 genes of different plant species. The OgPR1a cDNA has an apparent single open reading frame with a predicted molecular mass 40,621 Da and an isoelectic point of 5.14. Both in silico analysis and a transient expression assay in onion epidermal cells revealed that the OgPR1a protein could be localized in intercellular space in plants. The OgPR1a mRNA was strongly transcribed by the exogenous treatment with ethylene and jasmonic acid as well as protein phosphatase inhibitors. Additionally, ectopic expression of the OgPR1a conferred disease resistance on Arabidopsis to the bacterial and fungal infections. PMID:25289005

Targeted Therapies for Advanced Oesophagogastric Cancer: Recent Progress and Future Directions.

PubMed

Young, Kate; Chau, Ian

2016-01-01

The genomic landscape of oesophagogastric (OG) cancer is highly complex. The recent elucidation of some of the pathways involved has suggested a number of novel targets for therapy. This therapy is urgently required as with conventional chemotherapy regimens patients with advanced OG cancer still have a median overall survival of under a year. This review outlines the rationale for the current treatment of OG cancer with chemotherapy and describes both previously conducted and ongoing clinical trials of novel agents in this area. The targets and associated treatments discussed include HER-2, EGFR, VEGF, c-Met, FGFR-2, PI3K, mTOR andIGF-1. To date only two targeted treatments, trastuzumab and ramucirumab, have become part of the treatment paradigm for OG cancer, partly due to difficulties in defining predictive biomarkers in this disease. However, there are a number of promising drugs in the pipeline and this article seeks to describe these and other potential novel approaches including targeting DNA repair deficiencies and the immune system.

5-Carboxy-8-hydroxyquinoline is a Broad Spectrum 2-Oxoglutarate Oxygenase Inhibitor which Causes Iron Translocation

PubMed Central

Aik, WeiShen; Che, Ka Hing; Li, Xuan Shirley; Kristensen, Jan B. L.; King, Oliver N. F.; Chan, Mun Chiang; Yeoh, Kar Kheng; Choi, Hwanho; Walport, Louise J.; Thinnes, Cyrille C.; Bush, Jacob T.; Lejeune, Clarisse; Rydzik, Anna M.; Rose, Nathan R.; Bagg, Eleanor A.; McDonough, Michael A.; Krojer, Tobias; Yue, Wyatt W.; Ng, Stanley S.; Olsen, Lars; Brennan, Paul E.; Oppermann, Udo; Muller-Knapp, Susanne; Klose, Robert J.; Ratcliffe, Peter J.; Schofield, Christopher J.; Kawamura, Akane

2015-01-01

2-Oxoglutarate and iron dependent oxygenases are therapeutic targets for human diseases. Using a representative 2OG oxygenase panel, we compare the inhibitory activities of 5-carboxy-8-hydroxyquinoline (IOX1) and 4-carboxy-8-hydroxyquinoline (4C8HQ) with that of two other commonly used 2OG oxygenase inhibitors, N-oxalylglycine (NOG) and 2,4-pyridinedicarboxylic acid (2,4-PDCA). The results reveal that IOX1 has a broad spectrum of activity, as demonstrated by the inhibition of transcription factor hydroxylases, representatives of all 2OG dependent histone demethylase subfamilies, nucleic acid demethylases and γ-butyrobetaine hydroxylase. Cellular assays show that, unlike NOG and 2,4-PDCA, IOX1 is active against both cytosolic and nuclear 2OG oxygenases without ester derivatisation. Unexpectedly, crystallographic studies on these oxygenases demonstrate that IOX1, but not 4C8HQ, can cause translocation of the active site metal, revealing a rare example of protein ligand-induced metal movement PMID:26682036

Restaurant oil and grease management in Hong Kong.

PubMed

Yau, Yiu-Hung; Rudolph, Victor; Lo, Cat Chui-Man; Wu, Kam-Chau

2018-06-24

Oil and grease (O&G) in wastewater can be considered as two parts or proportion contained in emulsion which exceeded O&G standard. Most of oil becomes emulsified with water when they pass through grease trap and discharged in the effluents. Thus, it may indicate that either treatment of grease traps or standards for O&G content stipulated in technical memorandum of Water Pollution Control Ordinance (WPCO) do not reflect the actual situation. Existing grease traps should be upgraded to meet the requirements of WPCO. Alternative technologies need to be developed to tackle this unsolved problem. Good management and practices are also important to ensure proper collection and waste recycling rather than just disposing effluent into drains. Collected O&G content can be recycled as valuable products such as biofuel, flotation agent, or other derivatives. This approach not only protects the environment by improving water quality, it also encourages large flow restaurant operators to recycle oil and grease content towards cleaner production.

Improved regional-scale groundwater representation by the coupling of the mesoscale Hydrologic Model (mHM v5.7) to the groundwater model OpenGeoSys (OGS)

NASA Astrophysics Data System (ADS)

Jing, Miao; Heße, Falk; Kumar, Rohini; Wang, Wenqing; Fischer, Thomas; Walther, Marc; Zink, Matthias; Zech, Alraune; Samaniego, Luis; Kolditz, Olaf; Attinger, Sabine

2018-06-01

Most large-scale hydrologic models fall short in reproducing groundwater head dynamics and simulating transport process due to their oversimplified representation of groundwater flow. In this study, we aim to extend the applicability of the mesoscale Hydrologic Model (mHM v5.7) to subsurface hydrology by coupling it with the porous media simulator OpenGeoSys (OGS). The two models are one-way coupled through model interfaces GIS2FEM and RIV2FEM, by which the grid-based fluxes of groundwater recharge and the river-groundwater exchange generated by mHM are converted to fixed-flux boundary conditions of the groundwater model OGS. Specifically, the grid-based vertical reservoirs in mHM are completely preserved for the estimation of land-surface fluxes, while OGS acts as a plug-in to the original mHM modeling framework for groundwater flow and transport modeling. The applicability of the coupled model (mHM-OGS v1.0) is evaluated by a case study in the central European mesoscale river basin - Nägelstedt. Different time steps, i.e., daily in mHM and monthly in OGS, are used to account for fast surface flow and slow groundwater flow. Model calibration is conducted following a two-step procedure using discharge for mHM and long-term mean of groundwater head measurements for OGS. Based on the model summary statistics, namely the Nash-Sutcliffe model efficiency (NSE), the mean absolute error (MAE), and the interquartile range error (QRE), the coupled model is able to satisfactorily represent the dynamics of discharge and groundwater heads at several locations across the study basin. Our exemplary calculations show that the one-way coupled model can take advantage of the spatially explicit modeling capabilities of surface and groundwater hydrologic models and provide an adequate representation of the spatiotemporal behaviors of groundwater storage and heads, thus making it a valuable tool for addressing water resources and management problems.

OGS improvements in the year 2011 in running the Northeastern Italy Seismic Network

NASA Astrophysics Data System (ADS)

Bragato, P. L.; Pesaresi, D.; Saraò, A.; Di Bartolomeo, P.; Durı, G.

2012-04-01

The Centro di Ricerche Sismologiche (CRS, Seismological Research Center) of the Istituto Nazionale di Oceanografia e di Geofisica Sperimentale (OGS, Italian National Institute for Oceanography and Experimental Geophysics) in Udine (Italy) after the strong earthquake of magnitude M=6.4 occurred in 1976 in the Italian Friuli-Venezia Giulia region, started to operate the Northeastern Italy Seismic Network: it currently consists of 15 very sensitive broad band and 21 simpler short period seismic stations, all telemetered to and acquired in real time at the OGS-CRS data center in Udine. Real time data exchange agreements in place with other Italian, Slovenian, Austrian and Swiss seismological institutes lead to a total number of about 100 seismic stations acquired in real time, which makes the OGS the reference institute for seismic monitoring of Northeastern Italy. Since 2002 OGS-CRS is using the Antelope software suite on several workstations plus a SUN Cluster as the main tool for collecting, analyzing, archiving and exchanging seismic data, initially in the framework of the EU Interreg IIIA project "Trans-national seismological networks in the South-Eastern Alps". SeisComP is also used as a real time data exchange server tool. In order to improve the seismological monitoring of the Northeastern Italy area, at OGS-CRS we tuned existing programs and created ad hoc ones like: a customized web server named PickServer to manually relocate earthquakes, a script for automatic moment tensor determination, scripts for web publishing of earthquake parametric data, waveforms, state of health parameters and shaking maps, noise characterization by means of automatic spectra analysis, and last but not least scripts for email/SMS/fax alerting. The OGS-CRS Real Time Seismological website (RTS, http://rts.crs.inogs.it/) operative since several years was initially developed in the framework of the Italian DPC-INGV S3 Project: the RTS website shows classic earthquake locations parametric data plus ShakeMap and moment tensor information. At OGS-CRS we also spent a considerable amount of efforts in improving the long-period performances of broadband seismic stations, either by carrying out full re-installations and/or applying thermal insulations to the seismometers: more examples of PSD plots of the PRED broad band seismic station installation in the cave tunnel of Cave del Predil using a Quanterra Q330HR high resolution digitizer and a Sterckeisen STS-2 broadband seismometer will be illustrated. Efforts in strengthening the reliability of data links, exploring the use of redundant satellite/radio/GPRS links will also be shown.

Crystal Structure and Functional Analysis of Homocitrate Synthase, an Essential Enzyme in Lysine Biosynthesis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bulfer, Stacie L.; Scott, Erin M.; Couture, Jean-François

2010-01-12

Homocitrate synthase (HCS) catalyzes the first and committed step in lysine biosynthesis in many fungi and certain Archaea and is a potential target for antifungal drugs. Here we report the crystal structure of the HCS apoenzyme from Schizosaccharomyces pombe and two distinct structures of the enzyme in complex with the substrate 2-oxoglutarate (2-OG). The structures reveal that HCS forms an intertwined homodimer stabilized by domain-swapping between the N- and C-terminal domains of each monomer. The N-terminal catalytic domain is composed of a TIM barrel fold in which 2-OG binds via hydrogen bonds and coordination to the active site divalent metalmore » ion, whereas the C-terminal domain is composed of mixed {alpha}/{beta} topology. In the structures of the HCS apoenzyme and one of the 2-OG binary complexes, a lid motif from the C-terminal domain occludes the entrance to the active site of the neighboring monomer, whereas in the second 2-OG complex the lid is disordered, suggesting that it regulates substrate access to the active site through its apparent flexibility. Mutations of the active site residues involved in 2-OG binding or implicated in acid-base catalysis impair or abolish activity in vitro and in vivo. Together, these results yield new insights into the structure and catalytic mechanism of HCSs and furnish a platform for developing HCS-selective inhibitors.« less

Evolution of food provision to athletes at the summer Olympic Games.

PubMed

Pelly, Fiona E; O'Connor, Helen T; Denyer, Gareth S; Caterson, Ian D

2011-06-01

The history of food provision at the summer Olympic Games (OG) over the past century (1896-2008) provides insight into the evolution of sports nutrition research and the dietary strategies of athletes. Early research favoring protein as the main fuel for exercise was reflected in OG menus from 1932 to 1968. Despite conclusive research from the 1960s demonstrating the clear benefit of carbohydrate on exercise performance, a specific emphasis on carbohydrate-rich foods was not noted until the 1970s. Athlete food preferences and catering complexity evolved rapidly between 1970 and 2000, driven predominantly by a dramatic expansion of the OG and the emergence of systematic sports nutrition research. Nutritional advice by experts and sponsorship by food companies became increasingly important beginning with the 1984 Los Angeles OG. More recent developments include nutritional labeling of menu items and provision of a nutrition information desk (Barcelona 1992), demand for a "high-starch, low-fat menu" (Atlanta 1996), the addition of a dedicated menu website and the systematic gathering of information on athletes' apparent consumption (Sydney 2000), and appointment of the first international dietetic review committee (Beijing 2008). The history of catering at the OG tracks the evolution of sports nutrition practice from anecdotes and myth towards an established specialty in nutrition and dietetics grounded in evidence-based science. © 2011 International Life Sciences Institute.

Uridylylation of Herbaspirillum seropedicae GlnB and GlnK proteins is differentially affected by ATP, ADP and 2-oxoglutarate in vitro.

PubMed

Bonatto, Ana C; Souza, Emanuel M; Oliveira, Marco A S; Monteiro, Rose A; Chubatsu, Leda S; Huergo, Luciano F; Pedrosa, Fábio O

2012-08-01

PII are signal-transducing proteins that integrate metabolic signals and transmit this information to a large number of proteins. In proteobacteria, PII are modified by GlnD (uridylyltransferase/uridylyl-removing enzyme) in response to the nitrogen status. The uridylylation/deuridylylation cycle of PII is also regulated by carbon and energy signals such as ATP, ADP and 2-oxoglutarate (2-OG). These molecules bind to PII proteins and alter their tridimensional structure/conformation and activity. In this work, we determined the effects of ATP, ADP and 2-OG levels on the in vitro uridylylation of Herbaspirillum seropedicae PII proteins, GlnB and GlnK. Both proteins were uridylylated by GlnD in the presence of ATP or ADP, although the uridylylation levels were higher in the presence of ATP and under high 2-OG levels. Under excess of 2-OG, the GlnB uridylylation level was higher in the presence of ATP than with ADP, while GlnK uridylylation was similar with ATP or ADP. Moreover, in the presence of ADP/ATP molar ratios varying from 10/1 to 1/10, GlnB uridylylation level decreased as ADP concentration increased, whereas GlnK uridylylation remained constant. The results suggest that uridylylation of both GlnB and GlnK responds to 2-OG levels, but only GlnB responds effectively to variation on ADP/ATP ratio.

SalB inactivation modulates culture supernatant exoproteins and affects autolysis and viability in Enterococcus faecalis OG1RF.

PubMed

Shankar, Jayendra; Walker, Rachel G; Wilkinson, Mark C; Ward, Deborah; Horsburgh, Malcolm J

2012-07-01

The culture supernatant fraction of an Enterococcus faecalis gelE mutant of strain OG1RF contained elevated levels of the secreted antigen SalB. Using differential fluorescence gel electrophoresis (DIGE) the salB mutant was shown to possess a unique complement of exoproteins. Differentially abundant exoproteins were identified using matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry. Stress-related proteins including DnaK, Dps family protein, SOD, and NADH peroxidase were present in greater quantity in the OG1RF salB mutant culture supernatant. Moreover, several proteins involved in cell wall synthesis and cell division, including d-Ala-d-Lac ligase and EzrA, were present in reduced quantity in OG1RF salB relative to the parent strain. The salB mutant displayed reduced viability and anomalous cell division, and these phenotypes were exacerbated in a gelE salB double mutant. An epistatic relationship between gelE and salB was not identified with respect to increased autolysis and cell morphological changes observed in the salB mutant. SalB was purified as a six-histidine-tagged protein to investigate peptidoglycan hydrolytic activity; however, activity was not evident. High-pressure liquid chromatography (HPLC) analysis of reduced muropeptides from peptidoglycan digested with mutanolysin revealed that the salB mutant and OG1RF were indistinguishable.

Photocatalytic degradation of Orange G dye under solar light using nanocrystalline semiconductor metal oxide.

PubMed

Thennarasu, G; Kavithaa, S; Sivasamy, A

2011-08-01

The photocatalytic degradation of Orange G (OG) dye has been investigated using synthesised nanocrystalline ZnO as a photocatalyst and sunlight as the irradiation source. The formation of ZnO prepared from its precursor was confirmed through FT-IR and powder X-ray diffraction analyses. Surface morphology was characterised by scanning electron microscope and transmission electron microscope analysis. Band gap energy of synthesised nanocrystalline ZnO was calculated using diffuse reflectance spectroscopy (DRS). Different experimental parameters such as effects of pH, dye concentrations and mass of catalyst were standardised in order to achieve complete degradation of the dye molecules under solar light irradiation. The kinetics of oxidation of OG was also studied. The complete degradation of OG was evident after 90 min of irradiation at an initial pH of 6.86. The degradation of OG was confirmed by UV-Visible spectrophotometer, high-pressure liquid chromatography, ESI-Mass and chemical oxygen demand analyses. The adsorption of dye onto catalytic surface was analysed employing model equations such as Langmuir and Freundlich isotherms, and it was found that the Langmuir isotherm model best fitted the adsorption data. The solar photodegradation of OG followed pseudo-first-order kinetics. HPLC and ESI-Mass analyses of the degraded samples suggested that the dye molecules were readily degraded under solar irradiation with nanocrystalline ZnO.

Coleman works at the AR OGS Rack in the Node 3

NASA Image and Video Library

2011-02-08

ISS026-E-025143 (8 Feb. 2011) --- NASA astronaut Catherine (Cady) Coleman, Expedition 26 flight engineer, works at the Atmosphere Revitalization / Oxygen Generation System (AR OGS) rack in the Harmony node of the International Space Station. Coleman collected recirculation loop samples for subsequent analysis for pH value.

Coleman works at the AR OGS Rack in the Node 3

NASA Image and Video Library

2011-02-08

ISS026-E-025142 (8 Feb. 2011) --- NASA astronaut Catherine (Cady) Coleman, Expedition 26 flight engineer, works at the Atmosphere Revitalization / Oxygen Generation System (AR OGS) rack in the Harmony node of the International Space Station. Coleman collected recirculation loop samples for subsequent analysis for pH value.

Disclosing Information about Epilepsy and Type 1 Diabetes Mellitus: The Effect on Teachers' Understanding of Classroom Behavior

ERIC Educational Resources Information Center

Wodrich, David L.

2005-01-01

In an analog study, 122 continuing education and preservice teachers rated potential sources of one of two students' classroom problems. One student's behavior, described in a cumulative folder and a videotaped teacher/school psychologist conference, matched the symptoms of epilepsy, the other matched the symptoms of type 1 diabetes mellitus.…

Photographic copy of photograph (ca. 1934, original print located in ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Photographic copy of photograph (ca. 1934, original print located in Margaret Long Collection, Box 20, Folder 2, Western History Collections, Norlin Library, University of Colorado at Boulder). VIEW OF ROUTE OF SMOKY HILL TRAIL NORTH NEAR JUNCTION WITH BOX ELDER ROAD, VICINITY OF WATKINS, COLORADO - Box Elder Road, Between 104th & 112th Avenues, Hudson & Watkins Roads, Watkins, Adams County, CO

Paperless Contract Folder’s (PCF) DoD 5015.2 Certification

DTIC Science & Technology

2010-06-01

Draft Version Controls ...........................................................11 i. Electronic Routing of Purchase Request (Funding) Documents...of electronic records, version control , robust search and retrieval, and automated disposition that is compliant with legal requirements. As shown...h. Draft Version Controls Draft and versioning controls track the changes to the documents once they are saved. Draft numbers (0.1, 0.2, 0.3

Harnessing the Power of SharePoint for Library Applications

ERIC Educational Resources Information Center

Ennis, Lisa A.; Tims, Randy S.

2010-01-01

Back in 2008, the authors were looking for a tool that would replace the library's Outlook folders and much of what the library had stored on shared network drives. So they were mainly looking for something that would hold their documents, allow them to better organize those documents, offer an easy way to search for those documents, and be easy…

Fallon, Nevada FORGE Thermal-Hydrological-Mechanical Models

DOE Office of Scientific and Technical Information (OSTI.GOV)

Blankenship, Doug; Sonnenthal, Eric

Archive contains thermal-mechanical simulation input/output files. Included are files which fall into the following categories: ( 1 ) Spreadsheets with various input parameter calculations ( 2 ) Final Simulation Inputs ( 3 ) Native-State Thermal-Hydrological Model Input File Folders ( 4 ) Native-State Thermal-Hydrological-Mechanical Model Input Files ( 5 ) THM Model Stimulation Cases See 'File Descriptions.xlsx' resource below for additional information on individual files.

Confronting Substance Abuse: A Teacher's Guide.

ERIC Educational Resources Information Center

Boundy, Donna; Cochran, Kathleen Mayo; Miller, Robert A.; Rothbart, Betty

This packet is designed to be used by teachers in middle schools and high schools as they teach drug education. It accompanies a public television series, "Moyers on Addiction: Close at Home," but can be used on its own. The materials are in three parts. The first part is a folder that explains how to use the materials, provides a list of…

Combined Action Platoons in Vietnam

DTIC Science & Technology

2012-04-27

Action Platoons; The US Marines’ Other War (New York: Praeger Publishers 1989) 2 Ibid. 3 Al Hemingway , Our War Was Different: Marine Combined...USMC Archives: Vietnam War Collection 1954-75 Box 7 folder 25 coll/3808 38 Al Hemingway , Our War Was...Platoons; The US Marines’ Other War (New York: Praeger Publishers 1989), 37 40 Al Hemingway , Our War Was Different: Marine Combined Action Platoons

20 CFR 416.327 - Pilot program for photographic identification of disability benefit applicants in designated...

Code of Federal Regulations, 2010 CFR

2010-04-01

... Filing of Applications Applications § 416.327 Pilot program for photographic identification of disability... acting on your behalf must give SSA permission to take your photograph and make this photograph a part of the claims folder. You must give us this permission when you apply for benefits and/or when we ask for...

Units of Instruction for Vocational Office Education. Volume 1. Filing, Office Machines, and General Office Clerical Occupations. Teacher's Guide.

ERIC Educational Resources Information Center

East Texas State Univ., Commerce. Occupational Curriculum Lab.

Nineteen units on filing, office machines, and general office clerical occupations are presented in this teacher's guide. The unit topics include indexing, alphabetizing, and filing (e.g., business names); labeling and positioning file folders and guides; establishing a correspondence filing system; utilizing charge-out and follow-up file systems;…

78 FR 28495 - Safety Zone; Safety Precautions to Protect the Public from the Effects of a Potential...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-15

... Folder on the line associated with this rulemaking. You may also visit the Docket Management Facility in... the Port Lake Michigan. That safety zone has been effective and enforced since April 18, 2013, and... previously-mentioned safety zones on the Illinois River from Mile Marker 187.2 to Mile Marker 285.9. Since...

Survey of Mass Storage Systems

DTIC Science & Technology

1975-09-01

software that Pre- cision Instruments can provide. System Name: IBM 3850 Mass Storage System Manufacturer and Location: International Business Machines...34 Datamation, pp. 52-58, October 1973. 15 17. International Business Machines, IBM 3850 Mass Storage System Facts Folder, White Plains, NY, n.d. 18... International Business Machines, Introduction to the IBM 3850 Mass Storage System (MSS), White Plains, NY, n.d. 19. International Business Machines

The use of interactive technology in the classroom.

PubMed

Kresic, P

1999-01-01

This article discusses the benefits that clinical laboratory science students and instructors experienced through the use of and integration of computer technology, microscopes, and digitizing cameras. Patient specimens were obtained from the participating clinical affiliates, slides stained or wet mounts prepared, images viewed under the microscope, digitized, and after labeling, stored into an appropriate folder. The individual folders were labeled as Hematology, Microbiology, Chemistry, or Urinalysis. Students, after obtaining the necessary specimens and pertinent data, created case study presentations for class discussions. After two semesters of utilizing videomicroscopy/computer technology in the classroom, students and instructors realized the potential associated with the technology, namely, the vast increase in the amount of organized visual and scientific information accessible and the availability of collaborative and interactive learning to complement individualized instruction. The instructors, on the other hand, were able to provide a wider variety of visual information on individual bases. In conclusion, the appropriate use of technology can enhance students' learning and participation. Increased student involvement through the use of videomicroscopy and computer technology heightened their sense of pride and ownership in providing suitable information in case study presentations. Also, visualization provides students and educators with alternative methods of teaching/learning and increased retention of information.

[Educational guideline for the maternal orientation concerning the care with preterm infants].

PubMed

Fonseca, Luciana Mara Monti; Scochi, Carmen Gracinda Silvan; Rocha, Semiramis Melani Melo; Leite, Adriana Moraes

2004-01-01

This work aimed at describing the development of educational and instructional material for maternal training, so as to prepare the mother for the preterm infants' discharge from hospital, by means of the participatory methodology. The pedagogical model used was that of education for critical consciousness, based on Paulo Freire. Study participants were two nurses, two nursing auxiliaries and four mothers of preterm babies, which were hospitalized at the Intermediate Care Unit of a university hospital in Ribeirão Preto-SP, Brazil. The participants indicated the subjects of interest for the teaching-learning process, which were grouped into the categories: daily care, feeding, hygiene, special care and family relationship. We decided to develop an educational folder with figures, which could be taken home. This educational and instructional material was produced by the researchers on the basis of literature, their professional experience and on technical and scientific advice from other professionals. The final version of the folder was validated by the participants and now constitutes a creative instrument that can be of help in health education activities oriented towards these clients. According to the participants, the educational material directed the guidelines and helped the mothers to memorize the content that had to be learned.

Duty Module Methodology for Officer Career Management System Development: Task Data Bank, Task List.

DTIC Science & Technology

1975-11-01

and supply of communications equipment. O-G-1 0427 Prepare communications portion of unit SOP, operations orders, and plans. O-G-1 0428 Interpret...property for sale into commrercial categories. 0-FF-10 1307 Prepare formal advertising and invitations to bid and make other authorized arrangements for

On-The-Move Nutrient Delivery System (NDS): User Acceptability of Rotary Flow Control Version

DTIC Science & Technology

2009-04-01

Following: Salt, Sodium Citrate, Monopotassium Phosphate, Sodium Benzoate , Potassium Sorbate, FD & C Yellow #5. Faslln,,, Flow Mallifold 126.00 g (4.44 oz...Fat Cholesterol Sodium 440mg Potassium Total Carbohydrate Dietary Fiber Sugars Protein Vitamin A Vitamin C Calcium lron Phosphorus 260 o Og Og Omg 18

40 CFR 432.62 - Effluent limitations attainable by the application of the best practicable control technology...

Code of Federal Regulations, 2011 CFR

2011-07-01

....018 Fecal Coliform (2) (3) O&G 4 0.012 0.006 TSS 0.044 0.022 1 Pounds per 1000 lbs (or g/kg) of... million pounds per year of finished products must achieve the limitations for BOD5, fecal coliform, O&G...

40 CFR 432.82 - Effluent limitations attainable by the application of the best practicable control technology...

Code of Federal Regulations, 2011 CFR

2011-07-01

....31 Fecal Coliform (2) (3) O&G 4 0.22 0.11 TSS 0.74 0.37 1 Pounds per 1000 lbs (or g/kg) of finished... million pounds per year of finished products must achieve the limitations for BOD5, fecal coliform, O&G...

40 CFR 432.92 - Effluent limitations attainable by the application of the best practicable control technology...

Code of Federal Regulations, 2011 CFR

2011-07-01

....37 Fecal Coliform (2) (3) O&G 4 0.26 0.13 TSS 0.90 0.45 1 Pounds per 1000 lbs (or g/kg) of finished... million pounds per year of finished products must achieve the limitations for BOD5, fecal coliform, O&G...

40 CFR 432.82 - Effluent limitations attainable by the application of the best practicable control technology...

Code of Federal Regulations, 2010 CFR

2010-07-01

....31 Fecal Coliform (2) (3) O&G 4 0.22 0.11 TSS 0.74 0.37 1 Pounds per 1000 lbs (or g/kg) of finished... million pounds per year of finished products must achieve the limitations for BOD5, fecal coliform, O&G...

VERTICAL STRATIFICATION OF SOIL WATER STORAGE AND RELEASE DYNAMICS IN PACIFIC NORTHWEST CONIFEROUS FORESTS

EPA Science Inventory

abstract for journal article We characterized vertical variation in the seasonal depletion of stored soil moisture in old-growth ponderosa pine (OG-PP, xeric), and young and old-growth Douglas-fir (Y-DF, OG-DF, mesic) forests to evaluate changes in water availability for root up...

New Insights on Leucine-Rich Repeats Receptor-Like Kinase Orthologous Relationships in Angiosperms

PubMed Central

Dufayard, Jean-François; Bettembourg, Mathilde; Fischer, Iris; Droc, Gaetan; Guiderdoni, Emmanuel; Périn, Christophe; Chantret, Nathalie; Diévart, Anne

2017-01-01

Leucine-Rich Repeats Receptor-Like Kinase (LRR-RLK) genes represent a large and complex gene family in plants, mainly involved in development and stress responses. These receptors are composed of an LRR-containing extracellular domain (ECD), a transmembrane domain (TM) and an intracellular kinase domain (KD). To provide new perspectives on functional analyses of these genes in model and non-model plant species, we performed a phylogenetic analysis on 8,360 LRR-RLK receptors in 31 angiosperm genomes (8 monocots and 23 dicots). We identified 101 orthologous groups (OGs) of genes being conserved among almost all monocot and dicot species analyzed. We observed that more than 10% of these OGs are absent in the Brassicaceae species studied. We show that the ECD structural features are not always conserved among orthologs, suggesting that functions may have diverged in some OG sets. Moreover, we looked at targets of positive selection footprints in 12 pairs of OGs and noticed that depending on the subgroups, positive selection occurred more frequently either in the ECDs or in the KDs. PMID:28424707

Study of the 249-251Cf + 48Ca reactions: recent results and outlook

NASA Astrophysics Data System (ADS)

Voinov, A. A.; Oganessian, Yu Ts; Abdullin, F. Sh; Brewer, N. T.; Dmitriev, S. N.; Grzywacz, R. K.; Hamilton, J. H.; Itkis, M. G.; Miernik, K.; Polyakov, A. N.; Roberto, J. B.; Rykaczewski, K. P.; Sabelnikov, A. V.; Sagaidak, R. N.; Shirokovsky, I. V.; Shumeiko, M. V.; Stoyer, M. A.; Subbotin, V. G.; Sukhov, A. M.; Tsyganov, Yu S.; Utyonkov, V. K.; Vostokin, G. K.

2018-02-01

Experiment aiming at the synthesis of heavy isotopes of Z=118 (Og) using beam of 48Ca and a target of 249-251Cf was undertaken in October 2015 - April 2016 employing the Dubna Gas-Filled Recoil Separator (FLNR JINR). The target of mixed isotopes of 249-251Cf (50.7% of 249Cf, 12.9% of 250Cf, and 36.4% of 251Cf) was irradiated by 48Ca ions at two beam energies of 252 and 258 MeV with the corresponding accumulated beam doses of 1.6×1019 and 1.1×1019. A single event observed at lower beam energy was assigned to the isotope 294Og, the product of the reaction 249Cf(48Ca, 3n); its decay pattern and the observed radioactive properties of the nuclides in the decay chain reproduce in full those observed for 294Og in our earlier experiments of 2002-2005 and 2012. At higher beam energy we observed no decay chains that could be attributed to the isotopes of Og. The possibility of renewal of this experiment in the future is discussed.

Characterization of VOCs Emissions from Industrial Facilities and Natural Gas Production Sites: A Mobile Sensing Approach

NASA Astrophysics Data System (ADS)

Zhou, X.; Gu, J.; Trask, B.; Lyon, D. R.; Albertson, J. D.

2017-12-01

With the recent expansion of U.S. oil and gas (O&G) production, many studies have focused on the quantification of fugitive methane emissions. However, only a few studies have explored the emissions of volatile organic compounds (VOCs) from O&G production sites that affect human health in adjacent communities, both directly through exposure to toxic chemical compounds and indirectly via formation of ground-level ozone. In this study, we seek to quantify emissions of VOCs from O&G production sites and petrochemical facilities using a mobile sensing approach, with both high-end analyzers and relatively low-cost sensors. A probabilistic source characterization approach is used to estimate emission rates of VOCs, directly taking into account quantitative measure of sensor accuracy. This work will provide data with proper spatiotemporal resolution and coverage, so as to improve the understanding of VOCs emission from O&G production sites, VOCs-exposure of local communities, and explore the feasibility of low-cost sensors for VOCs monitoring. The project will provide an important foundational step to enable large scale studies.

Mechanical external work and recovery at preferred walking speed in obese subjects.

PubMed

Malatesta, Davide; Vismara, Luca; Menegoni, Francesco; Galli, Manuela; Romei, Marianna; Capodaglio, Paolo

2009-02-01

The aim of this study was to compare the mechanical external work (per kg) and pendular energy transduction at preferred walking speed (PWS) in obese versus normal body mass subjects to investigate whether obese adults adopt energy conserving gait mechanics. The mechanical external work (Wext) and the fraction of mechanical energy recovered by the pendular mechanism (Rstep) were computed using kinematic data acquired by an optoelectronic system and were compared in 30 obese (OG; body mass index [BMI] = 39.6 +/- 0.6 kg m(-2); 29.5 +/- 1.3 yr) and 19 normal body mass adults (NG; BMI = 21.4 +/- 0.5 kg m(-2); 31.2 +/- 1.2 yr) walking at PWS. PWS was significantly lower in OG (1.18 +/- 0.02 m s(-1)) than in NG (1.33 +/- 0.02 m s(-1); P

Pectin Biosynthesis Is Critical for Cell Wall Integrity and Immunity in Arabidopsis thaliana

PubMed Central

Bethke, Gerit; Thao, Amanda; Xiong, Guangyan; Hatsugai, Noriyuki; Katagiri, Fumiaki; Pauly, Markus

2016-01-01

Plant cell walls are important barriers against microbial pathogens. Cell walls of Arabidopsis thaliana leaves contain three major types of polysaccharides: cellulose, various hemicelluloses, and pectins. UDP-d-galacturonic acid, the key building block of pectins, is produced from the precursor UDP-d-glucuronic acid by the action of glucuronate 4-epimerases (GAEs). Pseudomonas syringae pv maculicola ES4326 (Pma ES4326) repressed expression of GAE1 and GAE6 in Arabidopsis, and immunity to Pma ES4326 was compromised in gae6 and gae1 gae6 mutant plants. These plants had brittle leaves and cell walls of leaves had less galacturonic acid. Resistance to specific Botrytis cinerea isolates was also compromised in gae1 gae6 double mutant plants. Although oligogalacturonide (OG)-induced immune signaling was unaltered in gae1 gae6 mutant plants, immune signaling induced by a commercial pectinase, macerozyme, was reduced. Macerozyme treatment or infection with B. cinerea released less soluble uronic acid, likely reflecting fewer OGs, from gae1 gae6 cell walls than from wild-type Col-0. Although both OGs and macerozyme-induced immunity to B. cinerea in Col-0, only OGs also induced immunity in gae1 gae6. Pectin is thus an important contributor to plant immunity, and this is due at least in part to the induction of immune responses by soluble pectin, likely OGs, that are released during plant-pathogen interactions. PMID:26813622

Effects of forage family on apparent ruminal synthesis of B vitamins in lactating dairy cows.

PubMed

Castagnino, D S; Seck, M; Beaudet, V; Kammes, K L; Linton, J A Voelker; Allen, M S; Gervais, R; Chouinard, P Y; Girard, C L

2016-03-01

Effects of forage family (legume vs. grass) on apparent ruminal synthesis (ARS) and postruminal supply of B vitamins were evaluated in 2 experiments. Diets containing either alfalfa (AL) or orchardgrass (OG) silages as the sole forage were offered to ruminally and duodenally cannulated lactating Holstein cows in crossover design experiments. Experiment 1 compared diets containing AL and OG [~23% forage neutral detergent fiber (NDF) and ~27% total NDF] offered to 8 cows in two 15-d treatment periods. Experiment 2 compared diets containing AL and OG (~25% forage NDF and ~30% total NDF) offered to 13 cows in two 18-d treatment periods. Thiamin, riboflavin, niacin, vitamin B6, folates, and vitamin B12 were analyzed in feeds and duodenal digesta. Apparent ruminal synthesis was calculated as the duodenal flow of each vitamin minus its intake. Forage family affected B vitamin intakes, duodenal flow, and ARS. In both experiments, AL diets increased vitamin B6 and decreased folate intakes. In experiment 1, riboflavin and niacin intakes were greater with the OG diet, whereas in experiment 2 thiamin intake was greater but riboflavin intake was smaller with the OG diet. In spite of the low contribution of either silage to the dietary folate content, folate intake was greater with OG diets than AL due to the difference in soybean meal contribution between diets. Niacin and folate ARS were not affected by the forage family. Duodenal microbial nitrogen flow was positively correlated with ARS of riboflavin, niacin, vitamin B6, folates, and vitamin B12, but tended to be negatively correlated with thiamin ARS. Apparent ruminal synthesis of folates and vitamin B12 appear to be related to microbial biomass activity. Changes in nutrient composition of the diets likely affected the microbial population in the rumen and their B vitamin metabolism. Copyright © 2016 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

Long-term Outcomes of Laparoscopic Versus Open Surgery for Clinical Stage II/III Gastric Cancer: A Multicenter Cohort Study in Japan (LOC-A Study).

PubMed

Kinoshita, Takahiro; Uyama, Ichiro; Terashima, Masanori; Noshiro, Hirokazu; Nagai, Eishi; Obama, Kazutaka; Tamamori, Yutaka; Nabae, Toshinaga; Honda, Michitaka; Abe, Takayuki

2018-04-24

A large-scale multicenter historical cohort study was conducted to investigate the efficacy of laparoscopic gastrectomy (LG) in comparison to open gastrectomy (OG) for locally advanced gastric cancer. LG is now practiced widely, but its applicability for advanced gastric cancer is still controversial. As oncologic outcomes of randomized trials are still pending, there is an urgent need for information that would be relevant to current practice. Through a consensus meeting involving surgeons and biostatisticians, 30 preoperative variables possibly influencing the choice of surgical approach and associated with outcome were identified to enable rigorous estimation of propensity scores. A total of 1948 consecutive patients who underwent gastrectomy for clinical stage II/III gastric adenocarcinoma between 2008 and 2014 were identified, and their clinical data were collected from 8 participating hospitals. After propensity score matching, 610 cases (OG = 305, LG = 305) were finally selected for comparison of long-term outcomes. In the propensity-matched OG and LG populations, the mean observation period was 3.5 and 3.4 years, and the 5-year overall survival was 53.0% and 54.2%, respectively. The hazard ratio (LG/OG) for overall survival was 1.01 (95% confidence interval, 0.80-1.29), and noninferiority of LG was demonstrated statistically as the upper 95% confidence limit was less than the prespecified margin (1.33). The recurrence rate was 30.8% and 29.8% for OG and LG, respectively, and the hazard ratio for recurrence was 0.98 (95% confidence interval, 0.74-1.31). The patterns of recurrence in the 2 groups were similar. This observational study strictly adjusted for confounding factors has provided evidence to suggest that LG is oncologically comparable to OG for locally advanced gastric cancer. The validity of this result will be examined in ongoing randomized trials.

Analysis of a long-term measurement of air pollutants (2007-2011) in North China Plain (NCP); Impact of emission reduction during the Beijing Olympic Games.

PubMed

Xu, Ruiguang; Tang, Guiqian; Wang, Yuesi; Tie, Xuexi

2016-09-01

Five years measurements were used to evaluate the effect of emission controls on the changes of air pollutants in Beijing and its surroundings in the NCP during 2008 Olympic Games (2008OG). The major challenge of this study was to filter out the effect of variability of meteorological conditions, when compared the air pollutants during the game to non-game period. We used four-year (2007, 2009-2011) average as the Non-2008OG to smooth the temporal variability caused by meteorological parameters. To study the spatial variability and regional transport, 6 sites (urban, rural, a mega city, a heavy industrial city, and a remote site) were selected. The result showed that the annually meteorological variability was significantly reduced. Such as, in BJ the differences between 2008OG and 5-years averaged values were 2.7% for relative humidity and 0.6% for wind speed. As a result, the anomaly of air pollutants between 2008OG and Non-2008OG can largely attribute to the emission control. The comparison showed that the major pollutants (PM10, PM2.5, NO, NOx) at the 6 sites in 2008OG were consistently lowered. For example, PM2.5 in BJ decreased from 75 to 45 μg/m(3) (40% reduction). However, the emission controls had minor effect on O3 concentrations (1% reduction). In contrast, the O3 precursor (NOx) reduced from 19.7 to 13.2 ppb (33% reduction). The in-sensitivity between NOx and O3 suggested that the O3 formation was under VOCs control condition in NCP, showing that strong VOC emission control is needed in order to significantly reduce O3 concentration in the region. Copyright © 2016 Elsevier Ltd. All rights reserved.

OpenGeoSys-GEMS: Hybrid parallelization of a reactive transport code with MPI and threads

NASA Astrophysics Data System (ADS)

Kosakowski, G.; Kulik, D. A.; Shao, H.

2012-04-01

OpenGeoSys-GEMS is a generic purpose reactive transport code based on the operator splitting approach. The code couples the Finite-Element groundwater flow and multi-species transport modules of the OpenGeoSys (OGS) project (http://www.ufz.de/index.php?en=18345) with the GEM-Selektor research package to model thermodynamic equilibrium of aquatic (geo)chemical systems utilizing the Gibbs Energy Minimization approach (http://gems.web.psi.ch/). The combination of OGS and the GEM-Selektor kernel (GEMS3K) is highly flexible due to the object-oriented modular code structures and the well defined (memory based) data exchange modules. Like other reactive transport codes, the practical applicability of OGS-GEMS is often hampered by the long calculation time and large memory requirements. • For realistic geochemical systems which might include dozens of mineral phases and several (non-ideal) solid solutions the time needed to solve the chemical system with GEMS3K may increase exceptionally. • The codes are coupled in a sequential non-iterative loop. In order to keep the accuracy, the time step size is restricted. In combination with a fine spatial discretization the time step size may become very small which increases calculation times drastically even for small 1D problems. • The current version of OGS is not optimized for memory use and the MPI version of OGS does not distribute data between nodes. Even for moderately small 2D problems the number of MPI processes that fit into memory of up-to-date workstations or HPC hardware is limited. One strategy to overcome the above mentioned restrictions of OGS-GEMS is to parallelize the coupled code. For OGS a parallelized version already exists. It is based on a domain decomposition method implemented with MPI and provides a parallel solver for fluid and mass transport processes. In the coupled code, after solving fluid flow and solute transport, geochemical calculations are done in form of a central loop over all finite element nodes with calls to GEMS3K and consecutive calculations of changed material parameters. In a first step the existing MPI implementation was utilized to parallelize this loop. Calculations were split between the MPI processes and afterwards data was synchronized by using MPI communication routines. Furthermore, multi-threaded calculation of the loop was implemented with help of the boost thread library (http://www.boost.org). This implementation provides a flexible environment to distribute calculations between several threads. For each MPI process at least one and up to several dozens of worker threads are spawned. These threads do not replicate the complete OGS-GEM data structure and use only a limited amount of memory. Calculation of the central geochemical loop is shared between all threads. Synchronization between the threads is done by barrier commands. The overall number of local threads times MPI processes should match the number of available computing nodes. The combination of multi-threading and MPI provides an effective and flexible environment to speed up OGS-GEMS calculations while limiting the required memory use. Test calculations on different hardware show that for certain types of applications tremendous speedups are possible.

Physical characteristics of Comet Nucleus C/2001 OG 108 (LONEOS)

NASA Astrophysics Data System (ADS)

Abell, Paul A.; Fernández, Yanga R.; Pravec, Petr; French, Linda M.; Farnham, Tony L.; Gaffey, Michael J.; Hardersen, Paul S.; Kušnirák, Peter; Šarounová, Lenka; Sheppard, Scott S.; Narayan, Gautham

2005-12-01

A detailed description of the Halley-type Comet C/2001 OG 108 (LONEOS) has been derived from visible, near-infrared, and mid-infrared observations obtained in October and November 2001. These data represent the first high-quality ground-based observations of a bare Halley-type comet nucleus and provide the best characterization of a Halley-type comet other than 1P/Halley itself. Analysis of time series photometry suggests that the nucleus has a rotation period of 57.2±0.5 h with a minimum nuclear axial ratio of 1.3, a phase-darkening slope parameter G of -0.01±0.10, and an estimated H=13.05±0.10. The rotation period of C/2001 OG 108 is one of the longest observed among comet nuclei. The V- R color index for this object is measured to be 0.46±0.02, which is virtually identical to that of other cometary nuclei and other possible extinct comet candidates. Measurements of the comet's thermal emission constrain the projected elliptical nuclear radii to be 9.6±1.0 km and 7.4±1.0 km, which makes C/2001 OG 108 one of the larger cometary nuclei known. The derived geometric albedo in V-band of 0.040±0.010 is typical for comet nuclei. Visible-wavelength spectrophotometry and near-infrared spectroscopy were combined to derive the nucleus's reflectance spectrum over a 0.4 to 2.5 μm wavelength range. These measurements represent one of the few nuclear spectra ever observed and the only known spectrum of a Halley-type comet. The spectrum of this comet nucleus is very nearly linear and shows no discernable absorption features at a 5% detection limit. The lack of any features, especially in the 0.8 to 1.0 μm range such as are seen in the spectra of carbonaceous chondrite meteorites and many low-albedo asteroids, is consistent with the presence of anhydrous rather than hydrous silicates on the surface of this comet. None of the currently recognized meteorites in the terrestrial collections have reflectance spectra that match C/2001 OG 108. The near-infrared spectrum, the geometric albedo, and the visible spectrophotometry all indicate that C/2001 OG 108 has spectral properties analogous to the D-type, and possibly P-type asteroids. Comparison of the measured albedo and diameter of C/2001 OG 108 with those of Damocloid asteroids reveals similarities between these asteroids and this comet nucleus, a finding which supports previous dynamical arguments that Damocloid asteroids could be composed of cometary-like materials. These observations are also consistent with findings that two Jupiter-family comets may have spectral signatures indicative of D-type asteroids. C/2001 OG 108 probably represents the transition from a typical active comet to an extinct cometary nucleus, and, as a Halley-type comet, suggests that some comets originating in the Oort cloud can become extinct without disintegrating. As a near-Earth object, C/2001 OG 108 supports the suggestion that some fraction of the near-Earth asteroid population consists of extinct cometary nuclei.

Well 9-1 Logs and Data: Roosevelt Hot Spring Area, Utah (FORGE)

DOE Data Explorer

Joe Moore

2016-03-03

This is a compilation of logs and data from Well 9-1 in the Roosevelt Hot Springs area in Utah. This well is also in the Utah FORGE study area. The file is in a compressed .zip format and there is a data inventory table (Excel spreadsheet) in the root folder that is a guide to the data that is accessible in subfolders.

Opening Our Doors: Taking Public Library Service to Preschool and Day-Care Facilities.

ERIC Educational Resources Information Center

Harris, Sally

The Opening Our Doors Project of the Pioneer Library System of Norman, Oklahoma takes public library service to preschool and day care facilities by means of learning kits housed in tote bags. The sturdy, zippered tote bags are full of books, games, toys, learning folders, and so forth. There is a tote bag for each of 75 different topics. Topics…

Teaching Folder Management System for the Enhancement of Engineering and Built Environment Faculty Program

ERIC Educational Resources Information Center

Ab-Rahman, Mohammad Syuhaimi; Mustaffa, Muhamad Azrin Mohd; Abdul, Nasrul Amir; Yusoff, Abdul Rahman Mohd; Hipni, Afiq

2015-01-01

A strong, systematic and well-executed management system will be able to minimize and coordinate workload. A number of committees need to be developed, which are joined by the department staffs to achieve the objectives that have been set. Another important aspect is the monitoring department in order to ensure that the work done is correct and in…

Characteristics of Limited English Proficient Hispanic Students in Programs for the Learning Disabled: Implications for Policy, Practice and Research. Part I. Report Summary.

ERIC Educational Resources Information Center

Ortiz, Alba A., Ed.; Polyzoi, Eleoussa, Ed.

An exploratory and descriptive study is reviewed which examined the identification and placement of 334 limited English proficient Hispanic students (grades 2-5) in learning disability programs. Ss' eligibility folders were examined to determine why they had been referred initially, how they were assessed, and to document the initial placement…

From Black Power to Hip-Hop: Jeffrey O.G. Ogbar

ERIC Educational Resources Information Center

Smiles, Robin V.

2005-01-01

While history for most conjures up images of places and experiences far removed, for Dr. Jeffrey O.G. Ogbar, the field provides a "wonderful medium" to illuminate contemporary issues as well. Much of Ogbar's current research centers on events occurring in the latter half of the 20th century, such as the civil rights and Black power…

Reading and Spelling Gains Following One Year of Orton-Gillingham Intervention in Singaporean Students with Dyslexia

ERIC Educational Resources Information Center

Lim, Lois; Oei, Adam C.

2015-01-01

Despite the widespread use of Orton-Gillingham (OG) based approaches to dyslexia remediation, empirical support documenting its effectiveness is lacking. Recently, Chia and Houghton demonstrated the effectiveness of the OG approach for remediation of dyslexia in Singapore. As a conceptual replication and extension of that research, we report…

Vertical stratification of soil water storage and release dynamics in Pacific Northwest coniferous forests.

Treesearch

J.M. Warren; F.C. Meinzer; J.R. Brooks; J.C. Domec

2005-01-01

We characterized vertical variation in the seasonal release of stored soil moisture in old-growth ponderosa pine (OG-PP, xeric), and young and old-growth Douglas-fir (Y-DF, OG-DF, mesic) forests to evaluate changes in water availability for root uptake. Soil water potential (ψ) and volumetric water content (θ...

40 CFR 432.125 - New source performance standards (NSPS).

Code of Federal Regulations, 2010 CFR

2010-07-01

... BOD5 26 16 Fecal Coliform (2) (3) O&G (as HEM) 14 8.0 TSS 30 20 1 mg/L (ppm). 2 Maximum of 400 MPN or... Ammonia (as N) 8.0 4.0 BOD5 26 16 Fecal Coliform (2) (3) O&G (as HEM) 14 8.0 TSS 30 20 Total Nitrogen 147...

40 CFR 432.115 - New source performance standards (NSPS).

Code of Federal Regulations, 2011 CFR

2011-07-01

... Coliform ( 2 ) ( 3 ) O&G (as HEM) 14 8.0 TSS 30 20 1 mg/L (ppm). 2 Maximum of 400 MPN or CFU per 100 mL at... Coliform (2) (3) O&G (as HEM) 14 8.0 TSS 30 20 Total Nitrogen 147 103 1 mg/L (ppm). 2 Maximum of 400 MPN or...

40 CFR 432.72 - Effluent limitations attainable by the application of the best practicable control technology...

Code of Federal Regulations, 2011 CFR

2011-07-01

... BOD5 0.56 0.28 Fecal Coliform (2) (3) O&G 4 0.20 0.10 TSS 0.68 0.34 1 Pounds per 1000 lbs (or g/kg) of... million pounds per year of finished products must achieve the limitations for BOD5, fecal coliform, O&G...

40 CFR 432.125 - New source performance standards (NSPS).

Code of Federal Regulations, 2011 CFR

2011-07-01

... BOD5 26 16 Fecal Coliform (2) (3) O&G (as HEM) 14 8.0 TSS 30 20 1 mg/L (ppm). 2 Maximum of 400 MPN or... Ammonia (as N) 8.0 4.0 BOD5 26 16 Fecal Coliform (2) (3) O&G (as HEM) 14 8.0 TSS 30 20 Total Nitrogen 147...

40 CFR 432.115 - New source performance standards (NSPS).

Code of Federal Regulations, 2010 CFR

2010-07-01

... Coliform ( 2 ) ( 3 ) O&G (as HEM) 14 8.0 TSS 30 20 1 mg/L (ppm). 2 Maximum of 400 MPN or CFU per 100 mL at... Coliform (2) (3) O&G (as HEM) 14 8.0 TSS 30 20 Total Nitrogen 147 103 1 mg/L (ppm). 2 Maximum of 400 MPN or...

Regulation of nitrate assimilation in cyanobacteria.

PubMed

Ohashi, Yoshitake; Shi, Wei; Takatani, Nobuyuki; Aichi, Makiko; Maeda, Shin-ichi; Watanabe, Satoru; Yoshikawa, Hirofumi; Omata, Tatsuo

2011-02-01

Nitrate assimilation by cyanobacteria is inhibited by the presence of ammonium in the growth medium. Both nitrate uptake and transcription of the nitrate assimilatory genes are regulated. The major intracellular signal for the regulation is, however, not ammonium or glutamine, but 2-oxoglutarate (2-OG), whose concentration changes according to the change in cellular C/N balance. When nitrogen is limiting growth, accumulation of 2-OG activates the transcription factor NtcA to induce transcription of the nitrate assimilation genes. Ammonium inhibits transcription by quickly depleting the 2-OG pool through its metabolism via the glutamine synthetase/glutamate synthase cycle. The P(II) protein inhibits the ABC-type nitrate transporter, and also nitrate reductase in some strains, by an unknown mechanism(s) when the cellular 2-OG level is low. Upon nitrogen limitation, 2-OG binds to P(II) to prevent the protein from inhibiting nitrate assimilation. A pathway-specific transcriptional regulator NtcB activates the nitrate assimilation genes in response to nitrite, either added to the medium or generated intracellularly by nitrate reduction. It plays an important role in selective activation of the nitrate assimilation pathway during growth under a limited supply of nitrate. P(II) was recently shown to regulate the activity of NtcA negatively by binding to PipX, a small coactivator protein of NtcA. On the basis of accumulating genome information from a variety of cyanobacteria and the molecular genetic data obtained from the representative strains, common features and group- or species-specific characteristics of the response of cyanobacteria to nitrogen is summarized and discussed in terms of ecophysiological significance.

Influence of forage species and diet particle size on the passage of digesta and nylon particles from the reticulorumen of steers.

PubMed

Prigge, E C; Fox, J T; Jacquemet, N A; Russell, R W

1993-10-01

To assess factors that influence the passage of digesta from the reticulorumen, ruminally fistulated steers (387 kg) were fed to appetite in a 4 x 4 Latin square design either orchardgrass (OG) (Dactylis glomerata L.) or switchgrass (SG) (Panicum virgatum L.) hays. The two hays were fed in either the long form or ground to pass a 2-cm screen. Steers fed OG diets had greater DMI (P < .05) than steers fed SG diets (11.7 vs 10.4 kg/d respectively). Particle size of ruminal digesta and feces determined by wet sieving was greater (P < .05) for the OG and long hay diets than for the SG and ground diets. Particle size of digesta collected from the anterior dorsal sac and anterior ventral sac of the rumen and from the reticulum did not vary (P > .25) with site. Conversely, ruminal concentrations of 1-mm nylon particles tended (P = .11) to be greater in the lower strata of the reticulorumen at 12 and 24 h after dosing. Neither a site effect nor a site x time-after-dosing interaction (P > .75) was observed for the 3- or 5-mm nylon particles, suggesting that a sorting process independent of specific gravity occurs in the rumen for smaller particles (before the reticulomasal orifice). Passage rate of the 1-mm nylon particles from the reticulorumen was greater (P < .01) for animals fed the SG than for those fed the OG diets, whereas for the 5-mm particles, passage rate was greater for the OG diets.(ABSTRACT TRUNCATED AT 250 WORDS)

Therapeutic potential of octyl gallate isolated from fruits of Terminalia bellerica in streptozotocin-induced diabetic rats.

PubMed

Latha, R Cecily Rosemary; Daisy, P

2013-06-01

Medicinal plants are a potential source of antidiabetic drugs. Terminalia bellerica Roxb. (Combretaceae) is used in Indian traditional systems of medicine to treat diabetes mellitus. The aim of this study was to isolate and identify antihyperglycemic principle(s) from the fruits of T. bellerica and assess the bioactivity in streptozotocin (STZ)-induced diabetic rats. Bioassay-guided fractionation was followed to isolate the active compound(s), structure was elucidated using (1)H and (13)C NMR, IR and mass spectrometry and administered intragastrically to diabetic Wistar rats at different doses (5, 10 and 20 mg/kg, body weight) for 28 d. Plasma glucose, insulin, C-peptide and other biochemical parameters were studied. Octyl gallate (OG) isolated first time from the fruit rind of T. bellerica significantly (p < 0.05) reduced plasma glucose to near normal values (108.47 ± 6.9 mg/dl) after 14 d at the dose of 20 mg/kg. In addition, OG significantly increased plasma insulin, C-peptide, total protein, albumin, tissue glycogen, body weight and markedly decreased serum total cholesterol, triglyceride, LDL-cholesterol, urea, uric acid and creatinine in diabetic rats. Also OG restored the altered regulatory enzymes of carbohydrate metabolism. OG might have augmented the secretion of insulin by the modulation of cAMP and intracellular calcium levels in the β cells of the pancreas. Our findings indicate that OG isolated first time from the fruit rind of T. bellerica has potential antidiabetic effect as it augments insulin secretion and normalizes the altered biochemical parameters in experimental diabetic rat models.

Evidence for the Slow Reaction of Hypoxia-Inducible Factor Prolyl Hydroxylase 2 with Oxygen

PubMed Central

Flashman, Emily; Hoffart, Lee M.; Hamed, Refaat B.; Bollinger, J. Martin; Krebs, Carsten; Schofield, Christopher J.

2010-01-01

SUMMARY The response of animals to hypoxia is mediated by the hypoxia-inducible transcription factor (HIF). Human HIF is regulated by four Fe(II) and 2-oxoglutarate (2OG) dependent oxygenases: Prolyl hydroxylase domain enzymes (PHDs or EGLNs) 1–3 catalyse hydroxylation of two prolyl-residues in HIF, triggering its degradation by the proteasome. Factor inhibiting HIF (FIH) catalyses hydroxylation of an asparagine-residue in HIF, inhibiting its transcriptional activity. Collectively, the HIF hydroxylases negatively regulate HIF in response to increasing oxygen concentration. Prolyl hydroxylase domain 2 (PHD2) is the most important oxygen sensor in human cells; however the underlying kinetic basis of the oxygen sensing function of PHD2 is unclear. We report analyses of the reaction of PHD2 with oxygen. Chemical quench/mass spectrometry experiments showed that reaction of a complex of PHD2, Fe(II), 2OG and the C-terminal oxygen-dependent degradation domain of HIF-α (CODD) with oxygen to form hydroxylated CODD and succinate is much slower (~100 fold) than for other similarly studied 2OG oxygenases. Stopped flow/UV-visible spectroscopy experiments showed that the reaction produces a relatively stable species absorbing at 320nm; Mössbauer spectroscopic experiments implied that this species is likely not a Fe(IV)=O intermediate, as observed for other 2OG oxygenases. Overall the results suggest that, at least compared to other studied 2OG oxygenases, PHD2 reacts relatively slowly with oxygen, a property that may be associated with its function as an oxygen sensor. PMID:20840591

Enhanced treatment of waste frying oil in an activated sludge system by addition of crude rhamnolipid solution.

PubMed

Zhang, Hongzi; Xiang, Hai; Zhang, Guoliang; Cao, Xia; Meng, Qing

2009-08-15

The presence of high-strength oil and grease (O&G) in wastewater poses serious challenges for environment. Addition of surfactant into the activated sludge bioreactor is feasible in reducing high concentrations of O&G via enhancing its bioavailability. In this paper, an aqueous biosurfactant solution of rhamnolipid as a cell-free culture broth of Pseudomonas aeruginosa zju.um1 was added into a batch of aerobic activated sludge system for treatment of the waste frying oil. This treatment was conducted on both bench and pilot-scales, whereas the removal efficiency of frying oil was determined by analyzing the residue concentration of O&G and chemical oxygen demand (COD). In the presence of varying concentrations of rhamnolipid from 22.5 mg/L to 90 mg/L, aerobic treatment for 30 h was enough to remove over 93% of O&G while this biodegradability was only 10% in the control system with the absence of rhamnolipids. The equivalent biodegradability was similarly obtained on COD under addition of rhamnolipid. Compared with bench studies, a higher treatment efficiency with the presence of rhamnolipids was achieved on a pilot-scale of activated sludge system, in which a short time of 12h was required for removing approximately 95% of O&G while the control treatment attained a low efficiency of 17%. Finally, foaming and biodegradability of rhamnolipids in activated sludge system were further examined in the whole treatment process. It seems that the addition of rhamnolipid-containing culture broth showed great potential for treatment of oily wastewater by activated sludge.

Modeled Oil and Gas Atmospheric Impacts in National Parks and Wilderness Areas in the Western US

NASA Astrophysics Data System (ADS)

Thompson, T. M.; Barna, M. G.; Schichtel, B. A.; Vimont, J.; Moore, C. T.

2014-12-01

Oil and gas production in the Western United States has increased considerably over the past 10 years. While many of the still limited oil and gas impact assessments have focused on potential human health impacts, the typically remote locations of production in the Intermountain West suggests that the impacts of oil and gas production on national parks and wilderness areas (class 1&2 areas) could also be important. To evaluate this, we utilize the Comprehensive Air quality Model with Extensions (CAMx) with two year-long modeling episodes representing 2008 and 2011, meteorology and emissions. The model inputs for the 2008 and 2011 episodes were generated as part of the West-wide Jump-start Air Quality Modeling Study (WestJumpAQMS) and Three State Air Quality Study (3SAQS) respectively. Both studies included a detailed assessment of oil and gas (O&G) emissions in Western States for the respective years. Each year-long modeling episode was run both with and without emissions from O&G production. The difference between these two runs provides an estimate of the contribution of the O&G production to air quality. These data were used to assess the contribution of O&G to the 8 hour average ozone concentrations, daily and annual fine particulate concentrations, annual nitrogen deposition totals and visibility in the modeling domain. We present the results for the class 1&2 areas in the Western US. We also present temporal trends of O&G impacts, differentiating between trends in urban and rural areas.

Plant immunity triggered by engineered in vivo release of oligogalacturonides, damage-associated molecular patterns.

PubMed

Benedetti, Manuel; Pontiggia, Daniela; Raggi, Sara; Cheng, Zhenyu; Scaloni, Flavio; Ferrari, Simone; Ausubel, Frederick M; Cervone, Felice; De Lorenzo, Giulia

2015-04-28

Oligogalacturonides (OGs) are fragments of pectin that activate plant innate immunity by functioning as damage-associated molecular patterns (DAMPs). We set out to test the hypothesis that OGs are generated in planta by partial inhibition of pathogen-encoded polygalacturonases (PGs). A gene encoding a fungal PG was fused with a gene encoding a plant polygalacturonase-inhibiting protein (PGIP) and expressed in transgenic Arabidopsis plants. We show that expression of the PGIP-PG chimera results in the in vivo production of OGs that can be detected by mass spectrometric analysis. Transgenic plants expressing the chimera under control of a pathogen-inducible promoter are more resistant to the phytopathogens Botrytis cinerea, Pectobacterium carotovorum, and Pseudomonas syringae. These data provide strong evidence for the hypothesis that OGs released in vivo act as a DAMP signal to trigger plant immunity and suggest that controlled release of these molecules upon infection may be a valuable tool to protect plants against infectious diseases. On the other hand, elevated levels of expression of the chimera cause the accumulation of salicylic acid, reduced growth, and eventually lead to plant death, consistent with the current notion that trade-off occurs between growth and defense.

α decay properties of 297Og within the two-potential approach

NASA Astrophysics Data System (ADS)

Deng, Jun-Gang; Cheng, Jun-Hao; Zheng, Bo; Li, Xiao-Hua

2017-12-01

The α decay half-life of the unknown nucleus 297Og is predicted within the two-potential approach, and α preformation probabilities of 64 odd-A nuclei in the region of proton numbers 82 < Z < 126 and neutron numbers 152 < N < 184, from 251Cf to 295Og, are extracted. In addition, based on the latest experimental data, a new set of parameters for α preformation probabilities considering the shell effect and proton-neutron interaction are obtained. The predicted α decay half-life of 297Og is 0.16 ms within a factor of 4.97. The predicted spin and parity of the ground states for 269Sg, 285Fl and 293Lv are 3/2+, 3/2+ and 5/2+, respectively. Supported by National Natural Science Foundation of China (11205083, 11505100), Construct Program of the Key Discipline in Hunan Province, the Research Foundation of Education Bureau of Hunan Province, China (15A159), the Natural Science Foundation of Hunan Province, China (2015JJ3103, 2015JJ2121), the Innovation Group of Nuclear and Particle Physics in USC, the Shandong Province Natural Science Foundation, China (ZR2015AQ007) and Hunan Provincial Innovation Foundation For Postgraduate (CX2017B536)

Regulation of GPR119 receptor activity with endocannabinoid-like lipids.

PubMed

Syed, Samreen K; Bui, Hai Hoang; Beavers, Lisa S; Farb, Thomas B; Ficorilli, James; Chesterfield, Amy K; Kuo, Ming-Shang; Bokvist, Krister; Barrett, David G; Efanov, Alexander M

2012-12-15

The GPR119 receptor plays an important role in the secretion of incretin hormones in response to nutrient consumption. We have studied the ability of an array of naturally occurring endocannabinoid-like lipids to activate GPR119 and have identified several lipid receptor agonists. The most potent receptor agonists identified were three N-acylethanolamines: oleoylethanolamine (OEA), palmitoleoylethanolamine, and linoleylethanolamine (LEA), all of which displayed similar potency in activating GPR119. Another lipid, 2-oleoylglycerol (2-OG), also activated GPR119 receptor but with significantly lower potency. Endogenous levels of endocannabinoid-like lipids were measured in intestine in fasted and refed mice. Of the lipid GPR119 agonists studied, the intestinal levels of only OEA, LEA, and 2-OG increased significantly upon refeeding. Intestinal levels of OEA and LEA in the fasted mice were low. In the fed state, OEA levels only moderately increased, whereas LEA levels rose drastically. 2-OG was the most abundant of the three GPR119 agonists in intestine, and its levels were radically elevated in fed mice. Our data suggest that, in lean mice, 2-OG and LEA may serve as physiologically relevant endogenous GPR119 agonists that mediate receptor activation upon nutrient uptake.

Plant immunity triggered by engineered in vivo release of oligogalacturonides, damage-associated molecular patterns

PubMed Central

Benedetti, Manuel; Pontiggia, Daniela; Raggi, Sara; Cheng, Zhenyu; Scaloni, Flavio; Ferrari, Simone; Ausubel, Frederick M.; Cervone, Felice; De Lorenzo, Giulia

2015-01-01

Oligogalacturonides (OGs) are fragments of pectin that activate plant innate immunity by functioning as damage-associated molecular patterns (DAMPs). We set out to test the hypothesis that OGs are generated in planta by partial inhibition of pathogen-encoded polygalacturonases (PGs). A gene encoding a fungal PG was fused with a gene encoding a plant polygalacturonase-inhibiting protein (PGIP) and expressed in transgenic Arabidopsis plants. We show that expression of the PGIP–PG chimera results in the in vivo production of OGs that can be detected by mass spectrometric analysis. Transgenic plants expressing the chimera under control of a pathogen-inducible promoter are more resistant to the phytopathogens Botrytis cinerea, Pectobacterium carotovorum, and Pseudomonas syringae. These data provide strong evidence for the hypothesis that OGs released in vivo act as a DAMP signal to trigger plant immunity and suggest that controlled release of these molecules upon infection may be a valuable tool to protect plants against infectious diseases. On the other hand, elevated levels of expression of the chimera cause the accumulation of salicylic acid, reduced growth, and eventually lead to plant death, consistent with the current notion that trade-off occurs between growth and defense. PMID:25870275

Well 14-2 Logs and Data: Roosevelt Hot Spring Area, Utah (Utah FORGE)

DOE Data Explorer

Joe Moore

2016-03-03

This is a compilation of logs and data from Well 14-2 in the Roosevelt Hot Springs area in Utah. This well is also in the Utah FORGE study area. The file is in a compressed .zip format and there is a data inventory table (Excel spreadsheet) in the root folder that is a guide to the data that is accessible in subfolders.

Well 52-21 Logs and Data: Roosevelt Hot Spring Area, Utah (Utah FORGE)

DOE Data Explorer

Joe Moore

2016-03-03

This is a compilation of logs and data from Well 52-21 in the Roosevelt Hot Springs area in Utah. This well is also in the Utah FORGE study area. The file is in a compressed .zip format and there is a data inventory table (Excel spreadsheet) in the root folder that is a guide to the data that is accessible in subfolders.

Well 82-33 Logs and Data: Roosevelt Hot Spring Area, Utah (Utah FORGE)

DOE Data Explorer

Joe Moore

2016-03-03

This is a compilation of logs and data from Well 82-33 in the Roosevelt Hot Springs area in Utah. This well is also in the Utah FORGE study area. The file is in a compressed .zip format and there is a data inventory table (Excel spreadsheet) in the root folder that is a guide to the data that is accessible in subfolders.

Countering Insider Threats - Handling Insider Threats Using Dynamic, Run-Time Forensics

DTIC Science & Technology

2007-10-01

able to handle the security policy requirements of a large organization containing many decentralized and diverse users, while being easily managed... contained in the TIF folder. Searching for any text string and sorting is supported also. The cache index file of Internet Explorer is not changed... containing thousands of malware software signatures. Separate datasets can be created for various classifications of malware such as encryption software

Organizing for Space: Creating a Trinitarian American Space Program - A Historical Primer

DTIC Science & Technology

2008-12-17

accomplishments concerning the prestige factor of human spaceflight. After Kennedy’s assassination and despite the subsequent Vietnam imbroglio, Johnson...the author has been able to discover in which JFK stated very explicitly the concept of beating the Russians to the moon. When Kennedy signed the...Ibid., 403-05. 40 NASA, News Release No. 61-115, May 25, 1961, folder: JFK - Miscellaneous Clippings, box: White House, Presidents, Kennedy

Contingency Contracting Smart Book.

DTIC Science & Technology

1987-08-01

E. RECOMMENDATION. That the Contingency Contracting "smart book" be either published as a DA pamphlet or the contents made part of a Field Manual ...pamphlet or the contents made part of a Field Manual . The Army can not continue without official guidance in this area, except at the risk of legal...construction suppl ies. d. Administrative and other supplies such as: (1) Office supplies (pencils, pens, paper, stapler , staples, carbon paper, folder

Filing Reprints: A Simple System For The Family Physician

PubMed Central

Berner, Mark

1978-01-01

This flexible method of filing medical literature without using cards is based on the International Classification of Health Problems in Primary Care. 1Articles, reprints, notes of lectures and rounds, etc. are filed in manilla folders according to a few simple guidelines. This system has proved to be practical and efficient, can be modified for individual needs, and once established requires little time to maintain. PMID:20469289

13. Photocopy of photograph. Photographer unknown, circa 1940. Original photograph ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

13. Photocopy of photograph. Photographer unknown, circa 1940. Original photograph can be found in Marvine Colliery folder in the archives of the Lackawanna Historical Society, Scranton, Pennsylvania. VIEW SHOWING SOUTH AND EAST FACADES OF BREAKER, WITH OVERHEAD PIPING IN FOREGROUND AND RETAIL SCALES OFFICE AT FAR RIGHT, LOOKING NORTHWEST - Marvine Colliery, Breaker No. 2, West side Boulevard Avenue, between East Parker Street & Route 380, Scranton, Lackawanna County, PA

Baseline coastal oblique aerial photographs collected from Navarre Beach, Florida, to Breton Island, Louisiana, September 18–19, 2015

USGS Publications Warehouse

Morgan, Karen L. M.

2016-08-01

In addition to the photographs, a Google Earth Keyhole Markup Language (KML) file is provided and can be used to view the images by clicking on the marker and then the thumbnail or the link below the thumbnail. The KML file was created using the photographic navigation files. This KML file can be found in the kml folder.

Well Acord 1-26 Logs and Data: Roosevelt Hot Spring Area, Utah (Utah FORGE)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Joe Moore

This is a compilation of logs and data from Well Acord 1-26 in the Roosevelt Hot Springs area in Utah. This well is also in the Utah FORGE study area. The file is in a compressed .zip format and there is a data inventory table (Excel spreadsheet) in the root folder that is a guide to the data that is accessible in subfolders.

Folding of a LysM Domain: Entropy-Enthalpy Compensation in the Transition State of an Ideal Two-state Folder

PubMed Central

Nickson, Adrian A.; Stoll, Kate E.; Clarke, Jane

2008-01-01

Protein-engineering methods (Φ-values) were used to investigate the folding transition state of a lysin motif (LysM) domain from Escherichia coli membrane-bound lytic murein transglycosylase D. This domain consists of just 48 structured residues in a symmetrical βααβ arrangement and is the smallest αβ protein yet investigated using these methods. An extensive mutational analysis revealed a highly robust folding pathway with no detectable transition state plasticity, indicating that LysM is an example of an ideal two-state folder. The pattern of Φ-values denotes a highly polarised transition state, with significant formation of the helices but no structure within the β-sheet. Remarkably, this transition state remains polarised after circularisation of the domain, and exhibits an identical Φ-value pattern; however, the interactions within the transition state are uniformly weaker in the circular variant. This observation is supported by results from an Eyring analysis of the folding rates of the two proteins. We propose that the folding pathway of LysM is dominated by enthalpic rather than entropic considerations, and suggest that the lower entropy cost of formation of the circular transition state is balanced, to some extent, by the lower enthalpy of contacts within this structure. PMID:18538343

Determining the migration duration of rice leaf folder (Cnaphalocrocis medinalis (Guenée)) moths using a trajectory analytical approach

PubMed Central

Wang, Feng-Ying; Yang, Fan; Lu, Ming-Hong; Luo, Shan-Yu; Zhai, Bao-Ping; Lim, Ka-Sing; McInerney, Caitríona E.; Hu, Gao

2017-01-01

Many moths finish their long distance migration after consecutive nights, but little is known about migration duration and distance. This information is key to predicting migration pathways and understanding their evolution. Tethered flight experiments have shown that ovarian development of rice leaf folder (Cnaphalocrocis medinalis [Guenée]) moths was accelerated and synchronized by flight in the first three nights, whereby most females were then matured for mating and reproduction. Thus, it was supposed that this moth might fly three nights to complete its migration. To test this hypothesis, 9 year’s field data for C. medinalis was collected from Nanning, Guangxi Autonomous Region in China. Forward trajectories indicated that most moths arrived at suitable breeding areas after three nights’ flight. Thus, for C. medinalis this migration duration and distance was a reasonable adaptation to the geographic distribution of suitable habitat. The development of female moth ovaries after three consecutive night flights appears to be a well-balanced survival strategy for this species to strike between migration and reproduction benefits. Hence, an optimum solution of migration-reproduction trade-offs in energy allocation evolved in response to the natural selection on migration route and physiological traits. PMID:28051132

Identification and Comparative Expression Profiles of Chemoreception Genes Revealed from Major Chemoreception Organs of the Rice Leaf Folder, Cnaphalocrocis medinalis (Lepidoptera: Pyralidae)

PubMed Central

Zeng, Fang-Fang; Zhao, Zhen-Fei; Yan, Miao-Jun; Zhou, Wen; Zhang, Zan; Zhang, Aijun; Lu, Zhong-Xian; Wang, Man-Qun

2015-01-01

To better understand the olfactory mechanisms in the rice leaf folder, Cnaphalocrocis medinalis (Guenée), a serious pest of rice in Asia, we established six partial transcriptomes from antennae, protarsus, and reproductive organs of male and female adults. A total of 102 transcripts were identified, including 29 odorant receptors (ORs), 15 ionotropic receptors (IRs), 30 odorant-binding proteins (OBPs), 26 chemosensory proteins (CSPs), and 2 sensory neuron membrane proteins (SNMPs). The expression patterns of these genes were calculated by fragments per kilobase of exon per million fragments mapped (FPKM) and validated by real-time quantitative PCR (RT-qPCR). Some transcripts were exclusively expressed in specific organs, such as female protarsus, whereas others were universally expressed, this varied expression profile may provide insights into the specific functions mediated by chemoreception proteins in insects. To the best of our knowledge, among the 102 identified transcripts, 81 are novel and have never been reported before. In addition, it also is the first time that ORs and IRs are identified in C. medinalis. Our findings significantly enhance the currently limited understanding olfactory mechanisms of the olfactory mechanisms underlying the chemoreception system in C. medinalis. PMID:26657286

A new overgrowth syndrome is due to mutations in RNF125.

PubMed

Tenorio, Jair; Mansilla, Alicia; Valencia, María; Martínez-Glez, Víctor; Romanelli, Valeria; Arias, Pedro; Castrejón, Nerea; Poletta, Fernando; Guillén-Navarro, Encarna; Gordo, Gema; Mansilla, Elena; García-Santiago, Fé; González-Casado, Isabel; Vallespín, Elena; Palomares, María; Mori, María A; Santos-Simarro, Fernando; García-Miñaur, Sixto; Fernández, Luis; Mena, Rocío; Benito-Sanz, Sara; del Pozo, Ángela; Silla, Juan Carlos; Ibañez, Kristina; López-Granados, Eduardo; Martín-Trujillo, Alex; Montaner, David; Heath, Karen E; Campos-Barros, Ángel; Dopazo, Joaquín; Nevado, Julián; Monk, David; Ruiz-Pérez, Víctor L; Lapunzina, Pablo

2014-12-01

Overgrowth syndromes (OGS) are a group of disorders in which all parameters of growth and physical development are above the mean for age and sex. We evaluated a series of 270 families from the Spanish Overgrowth Syndrome Registry with no known OGS. We identified one de novo deletion and three missense mutations in RNF125 in six patients from four families with overgrowth, macrocephaly, intellectual disability, mild hydrocephaly, hypoglycemia, and inflammatory diseases resembling Sjögren syndrome. RNF125 encodes an E3 ubiquitin ligase and is a novel gene of OGS. Our studies of the RNF125 pathway point to upregulation of RIG-I-IPS1-MDA5 and/or disruption of the PI3K-AKT and interferon signaling pathways as the putative final effectors. © 2014 WILEY PERIODICALS, INC.

Hubble Space Telescope Reduced-Gyro Control Law Design, Implementation, and On-Orbit Performance

NASA Technical Reports Server (NTRS)

Clapp, Brian R.; Ramsey, Patrick R.; Wirzburger, John H.; Smith, Daniel C.; VanArsadall, John C.

2008-01-01

Following gyro failures in April 2001 and April 2003, HST Pointing Control System engineers designed reduced-gyro control laws to extend the spacecraft science mission. The Two-Gyro Science (TGS) and One-Gyro Science (OGS) control laws were designed and implemented using magnetometers, star trackers, and Fine Guidance Sensors in succession to control vehicle rate about the missing gyro axes. Both TGS and OGS have demonstrated on-orbit pointing stability of 7 milli-arcseconds or less, which depends upon the guide star magnitude used by the Fine Guidance Sensor. This paper describes the design, implementation, and on-orbit performance of the TGS and OGS control law fine-pointing modes using Fixed Head Star Trackers and Fine Guidance Sensors, after successfully achieving coarse-pointing control using magnetometers.

Land use and land management effects on soil organic carbon stock in Mediterranean agricultural areas (Southern Spain)

NASA Astrophysics Data System (ADS)

Parras-Alcántara, Luis; Lozano-García, Beatriz

2014-05-01

INTRODUCTION Soils play a key role in the carbon geochemical cycle. Agriculture contributes to carbon sequestration through photosynthesis and the incorporation of carbon into carbohydrates. Soil management is one of the best tools for climate change mitigation. Small increases or decreases in soil carbon content due to changes in land use or management practices, may result in a significant net exchange of carbon between the soil carbon pool and the atmosphere. In the last decades arable crops (AC) have been transformed into olive grove cultivations (OG) or vineyards (V) in Mediterranean areas. A field study was conducted to determine long-term effects of land use change (LUC) (AC by OG and V) on soil organic carbon (SOC), total nitrogen (TN), C:N ratio and their stratification in Calcic-Chromic Luvisols (LVcc/cr) in Mediterranean conditions. MATERIAL AND METHODS An unirrigated farm in Montilla-Moriles (Córdoba, Spain) cultivated under conventional tillage (animal power with lightweight reversible plows and non-mineral fertilization or pesticides) was selected for study in 1965. In 1966, the farm was divided into three plots with three different uses (AC, OG and V). The preliminary analyses were realized in 1965 for AC (AC1), and the second analyses were realized in 2011 for AC (AC2 - winter crop rotation with annual wheat and barley, receiving mineral fertilization or pesticides), OG (annual passes with disk harrow and cultivator in the spring, followed by a tine harrow in the summer receiving mineral fertilization and weed control with residual herbicides), and V (with three or five chisel passes a year from early spring to early autumn with mineral fertilization or pesticides.). In all cases (AC1, AC2, OG and V) were collected soil entire profiles. Soil properties determined were: soil particle size, bulk density, SOC, TN, C:N ratio, stocks and SRs. The statistical significance of the differences in the variables between land use practices was tested using the Anderson-Darling test at each horizon or a combination of horizons for each soil type. RESULTS The LUC had a negative impact in the soil, reducing the SOC and TN stocks. The conversion from AC to V and OG involved the loss of the SOC stock (52.7% and 64.9% to V and OG respectively) and the loss of the TN stock (42.6% and 38.1% to V and OG respectively). The reduction of SOC by LUC, can be explained by a degraded process (due to vegetation losses and unsustainable soil management, which result in progressive impoverishment in the soil organic matter (OM) content, causing low productivity, which derived in unsuitable chemical properties) and by the reduced input of OM in cultivated soils, which reduced physical protection of soil and increased water erosion. However, 46 years of LUC had a positive effect in the soil, increasing the SR (in V and OG) of SOC, TN and C:N ratio (Parras-Alcántara et al., 2013). REFERENCES Parras-Alcántara, L., Martín-Carrillo, M., Lozano-García, B. 2013. Impacts of land use change in soil carbon and nitrogen in a Mediterranean agricultural area (Southern Spain). Solid Earth, 4: 167-177.

40 CFR 75.19 - Optional SO2, NOX, and CO2 emissions calculation for low mass emissions (LME) units.

Code of Federal Regulations, 2012 CFR

2012-07-01

... hourly SO2 mass emissions under this section. Alternatively, for fuel oil combustion, a lower, fuel... (or ozone season) prior to the year of the test (g H2O/g air). Ho = Observed humidity ratio during the test run (g H2O/g air). Tr = Average annual atmospheric temperature (or average ozone season...

Students' Decision Steps in Meta-Cognitive Learning in Free Online Groups (MetaL-FrOG): A Case Study

ERIC Educational Resources Information Center

Sen Fa, Kinsley Ng; Hussin, Firuz Hussin

2011-01-01

What prompts the students to respond in online dialogic discussion? Why some students chose to fall out? This case study through the lens of phenomenography observation attempts to explain the five decision steps of students to respond in Meta-cognitive Learning in Free Online Groups (MetaL-FrOG) discussion. It presents a part of a research…

Quantifying, Assessing, and Mitigating Methane Emissions from Super-emitters in the Oil and Gas Supply Chain

NASA Astrophysics Data System (ADS)

Lyon, David Richard

Methane emissions from the oil and gas (O&G) supply chain reduce potential climate benefits of natural gas as a replacement for other fossil fuels that emit more carbon dioxide per energy produced. O&G facilities have skewed emission rate distributions with a small fraction of sites contributing the majority of emissions. Knowledge of the identity and cause of these high emission facilities, referred to as super-emitters or fat-tail sources, is critical for reducing supply chain emissions. This dissertation addresses the quantification of super-emitter emissions, assessment of their prevalence and relationship to site characteristics, and mitigation with continuous leak detection systems. Chapter 1 summarizes the state of the knowledge of O&G methane emissions. Chapter 2 constructs a spatially-resolved emission inventory to estimate total and O&G methane emissions in the Barnett Shale as part of a coordinated research campaign using multiple top-down and bottom-up methods to quantify emissions. The emission inventory accounts for super-emitters with two-phase Monte Carlo simulations that combine site measurements collected with two approaches: unbiased sampling and targeted sampling of super-emitters. More comprehensive activity data and the inclusion of super-emitters, which account for 19% of O&G emissions, produces a emission inventory that is not statistically different than top-down regional emission estimates. Chapter 3 describes a helicopter-based survey of over 8,000 well pads in seven basins with infrared optical gas imaging to assess high emission sources. Four percent of sites are observed to have high emissions with over 90% of observed sources from tanks. The occurrence of high emissions is weakly correlated to site parameters and the best statistical model explains only 14% of variance, which demonstrates that the occurrence of super-emitters is primarily stochastic. Chapter 4 presents a Gaussian dispersion model for optimizing the placement of continuous leak detection systems at three example well pads. The model demonstrates that large leaks can be detected quickly with first generation systems. Continuous leak detection can be used in the near future to cost-effectively mitigate methane emissions from O&G super-emitters.

Mouse alpha1(I)-collagen promoter is the best known promoter to drive efficient Cre recombinase expression in osteoblast.

PubMed

Dacquin, Romain; Starbuck, Michael; Schinke, Thorsten; Karsenty, Gérard

2002-06-01

Cell- and time-specific gene inactivation should enhance our knowledge of bone biology. Implementation of this technique requires construction of transgenic mouse lines expressing Cre recombinase in osteoblasts, the bone forming cell. We tested several promoter fragments for their ability to drive efficient Cre expression in osteoblasts. In the first mouse transgenic line, the Cre gene was placed under the control of the 2.3-kb proximal fragment of the alpha1(I)-collagen promoter, which is expressed at high levels in osteoblasts throughout their differentiation. Transgenic mice expressing this transgene in bone were bred with the ROSA26 reporter (R26R) strain in which the ROSA26 locus is targeted with a conditional LacZ reporter cassette. In R26R mice, Cre expression and subsequent Cre-mediated recombination lead to expression of the LacZ reporter gene, an event that can be monitored by LacZ staining. LacZ staining was detected in virtually all osteoblasts of alpha1(I)-Cre;R26R mice indicating that homologous recombination occurred in these cells. No other cell type stained blue. In the second line studied, the 1.3-kb fragment of osteocalcin gene 2 (OG2) promoter, which is active in differentiated osteoblasts, was used to drive Cre expression. OG2-Cre mice expressed Cre specifically in bone. However, cross of OG2-Cre mice with R26R mice did not lead to any detectable LacZ staining in osteoblasts. Lastly, we tested a more active artificial promoter derived from the OG2 promoter. The artificial OG2-Cre transgene was expressed by reverse transcriptase-polymerase chain reaction in cartilage and bone samples. After cross of the artificial OG2-Cre mice with R26R mice, we detected a LacZ staining in articular chondrocytes but not in osteoblasts. Our data suggest that the only promoter able to drive Cre expression at a level sufficient to induce recombination in osteoblasts is the alpha1(I)-collagen promoter. Copyright 2002 Wiley-Liss, Inc.

Experimental and theoretical investigation of homogeneous gaseous reaction of CO2(g) + nH2O(g) + nNH3(g) → products (n = 1, 2).

PubMed

Li, Zhuangjie; Zhang, Baoquan

2012-09-13

Decreasing CO2 emissions into the atmosphere is key for reducing global warming. To facilitate the CO2 emission reduction efforts, our laboratory conducted experimental and theoretical investigations of the homogeneous gaseous reaction of CO2(g) + nH2O(g) + nNH3(g) → (NH4)HCO3(s)/(NH4)2CO3(s) (n = 1 and 2) using Fourier transform infrared attenuated total reflectance (FTIR-ATR) spectroscopy and ab initio molecular orbital theory. Our FTIR-ATR experimental results indicate that (NH4)2CO3(s) and (NH4)HCO3(s) are formed as aerosol particulate matter when carbon dioxide reacts with ammonia and water in the gaseous phase at room temperature. Ab initio study of this chemical system suggested that the reaction may proceed through formation of NH3·H2O(g), NH3·CO2(g), and CO2·H2O(g) complexes. Subsequent complexes, NH3·H2O·CO2 and (NH3)2·H2O·CO2, can be formed by adding gaseous reactants to the NH3·H2O(g), NH3·CO2(g), and CO2·H2O(g) complexes, respectively. The NH3·H2O·CO2 and (NH3)2·H2O·CO2 complexes can then be rearranged to produce (NH4)HCO3 and (NH4)2CO3 as final products via a transition state, and the NH3 molecule acts as a medium accepting and donating hydrogen atoms in the rearrangement process. Our computational results also reveal that the presence of an additional water molecule can reduce the activation energy of the rearrangement process. The high activation energy predicted in the present work suggests that the reaction is kinetically not favored, and our experimental observation of (NH4)HCO3(s) and (NH4)2CO3(s) may be attributed to the high concentrations of reactants increasing the reaction rate of the title reactions in the reactor.

Effect of High-Intensity Interval Training on Plasma Omentin-1 Concentration in Overweight/Obese and Normal-Weight Youth

PubMed Central

Ouerghi, Nejmeddine; Fradj, Mohamed Kacem Ben; Bezrati, Ikram; Feki, Moncef; Kaabachi, Naziha; Bouassida, Anissa

2017-01-01

Objectives Omentin-1 is a recently discovered adipokine, mainly produced by visceral adipose tissue, which is thought to improve insulin sensitivity. The study aimed to assess the association of plasma omentin-1 with cardiometabolic traits and physical performance and to test its response to high-intensity interval training (HIIT) in obese and normal-weight subjects. Methods Nine overweight/obese (OG) and 9 normal-weight (NWG) young men performed an 8-week HIIT program. Body composition, physical performance, homeostasis model assessment index for insulin resistance (HOMA-IR) as well as plasma omentin-1and lipid levels were assessed before and after the HIIT program. Results Baseline plasma omentin-1 was lower in OG than NWG men (359 ± 138 vs. 470 ± 114 ng/ml; p = 0.052). Plasma omentin-1 was related to body fat (r = −0.57; p = 0.03) and LDL-cholesterol (r = −0.49; p = 0.04). There was a trend towards significant association of omentin-1 with BMI (r = −0.47; p = 0.06) and VO2max (r = 0.41; p = 0.09). However, no association was observed with HOMA-IR. Following the HIIT program, omentin-1 concentrations have significantly (p < 0.01) increased in OG (359 ± 138 to 455 ± 126 ng/ml) and NWG men (470 ± 114 to 572 ± 115 ng/ml). In parallel, the cardiometabolic profile has improved with a significant decrease of HOMA-IR in OG. Conclusions HIIT resulted in a plasma omentin-1 increase and an improvement with regard to cardiometabolic traits in the OG men, which may contribute to modulate insulin sensitivity. PMID:28787708

Longitudinal assessment of childhood optic gliomas: relationship between flicker visual evoked potentials and magnetic resonance imaging findings.

PubMed

Falsini, Benedetto; Ziccardi, Lucia; Lazzareschi, Ilaria; Ruggiero, Antonio; Placentino, Luca; Dickmann, Anna; Liotti, Lucia; Piccardi, Marco; Balestrazzi, Emilio; Colosimo, Cesare; Di Rocco, Concezio; Riccardi, Riccardo

2008-05-01

The aim of this study was to evaluate longitudinally functional and neuro-radiologic findings in childhood optic gliomas (OG), by comparing flicker visual evoked potentials (F-VEPs) with brain magnetic resonance imaging (MRI) changes. Fourteen children (age range: 1-13 years) with OGs underwent serial F-VEP, MRI and neuro-ophthalmic examinations over a 38 month (median, range: 6-76) follow-up. F-VEPs were elicited by 8 Hz sine-wave flicker stimuli presented in a mini-Ganzfeld. Contrast-enhanced MRI examinations were performed. Results of both tests were blindly assessed by independent evaluators. F-VEPs were judged to be improved, stable or worsened if changes in the amplitude and/or phase angle of the response exceeded the limits of test-retest variability (+/-90th percentile) established for the same patients. MRI results were judged to show regression, stabilization or progression of OG based on its changes in size (+/-20%) or extension. Two to seven pairs of F-VEP/MRI examinations per patient (median: 4) were collected. Based on a total of 38 pairs of F-VEP/MRI examinations, both tests agreed in showing worsening (progression), stabilization and improvement (regression) in 5, 15 and 10 cases, respectively. In 3 cases, F-VEPs showed a worsening and MRI a stabilization, while in 5 cases F-VEPs showed an improvement and MRI a stabilization. Agreement between F-VEP and MRI changes was 78.9% (95% CI: +/- 37%, K statistics = 0.67, P < 0.001). The results indicate that longitudinal F-VEP changes can predict changes in MRI-assessed OG size and extension, providing a non-invasive functional assay, complementary to neuro-imaging, for OG follow-up.

Effect of High-Intensity Interval Training on Plasma Omentin-1 Concentration in Overweight/Obese and Normal-Weight Youth.

PubMed

Ouerghi, Nejmeddine; Ben Fradj, Mohamed Kacem; Bezrati, Ikram; Feki, Moncef; Kaabachi, Naziha; Bouassida, Anissa

2017-01-01

Omentin-1 is a recently discovered adipokine, mainly produced by visceral adipose tissue, which is thought to improve insulin sensitivity. The study aimed to assess the association of plasma omentin-1 with cardiometabolic traits and physical performance and to test its response to high-intensity interval training (HIIT) in obese and normal-weight subjects. Nine overweight/obese (OG) and 9 normal-weight (NWG) young men performed an 8-week HIIT program. Body composition, physical performance, homeostasis model assessment index for insulin resistance (HOMA-IR) as well as plasma omentin-1and lipid levels were assessed before and after the HIIT program. Baseline plasma omentin-1 was lower in OG than NWG men (359 ± 138 vs. 470 ± 114 ng/ml; p = 0.052). Plasma omentin-1 was related to body fat (r = -0.57; p = 0.03) and LDL-cholesterol (r = -0.49; p = 0.04). There was a trend towards significant association of omentin-1 with BMI (r = -0.47; p = 0.06) and VO2max (r = 0.41; p = 0.09). However, no association was observed with HOMA-IR. Following the HIIT program, omentin-1 concentrations have significantly (p < 0.01) increased in OG (359 ± 138 to 455 ± 126 ng/ml) and NWG men (470 ± 114 to 572 ± 115 ng/ml). In parallel, the cardiometabolic profile has improved with a significant decrease of HOMA-IR in OG. HIIT resulted in a plasma omentin-1 increase and an improvement with regard to cardiometabolic traits in the OG men, which may contribute to modulate insulin sensitivity. © 2017 The Author(s) Published by S. Karger GmbH, Freiburg.

Tactical Behaviors in Men's 800-m Olympic and World-Championship Medalists: A Changing of the Guard.

PubMed

Sandford, Gareth N; Pearson, Simon; Allen, Sian V; Malcata, Rita M; Kilding, Andrew E; Ross, Angus; Laursen, Paul B

2018-02-01

To assess the longitudinal evolution of tactical behaviors used to medal in men's 800-m Olympic Games (OG) or world-championship (WC) events in the recent competition era (2000-2016). Thirteen OG and WC events were characterized for 1st- and 2nd-lap splits using available footage from YouTube. Positive pacing strategies were defined as a faster 1st lap. Season's best 800-m time and world ranking, reflective of an athlete's "peak condition," were obtained to determine relationships between adopted tactics and physical condition prior to the championships. Seven championship events provided coverage of all medalists to enable determination of average 100-m speed and sector pacing of medalists. From 2011 onward, 800-m OG and WC medalists showed a faster 1st lap by 2.2 ± 1.1 s (mean, ±90% confidence limits; large difference, very likely), contrasting a possibly faster 2nd lap from 2000 to 2009 (0.5, ±0.4 s; moderate difference). A positive pacing strategy was related to a higher world ranking prior to the championships (r = .94, .84-.98; extremely large, most likely). After 2011, the fastest 100-m sector from 800-m OG and WC medalists was faster than before 2009 by 0.5, ±0.2 m/s (large difference, most likely). A secular change in tactical racing behavior appears evident in 800-m championships; since 2011, medalists have largely run faster 1st laps and have faster 100-m sector-speed requirements. This finding may be pertinent for training, tactical preparation, and talent identification of athletes preparing for 800-m running at OGs and WCs.

Data inconsistencies from states with unconventional oil and gas activity.

PubMed

Malone, Samantha; Kelso, Matthew; Auch, Ted; Edelstein, Karen; Ferrar, Kyle; Jalbert, Kirk

2015-01-01

The quality and availability of unconventional oil and gas (O&G) data in the United States have never been compared methodically state-to-state. By conducting such an assessment, this study seeks to better understand private and publicly sourced data variability and to identify data availability gaps. We developed an exploratory data-grading tool - Data Accessibility and Usability Index (DAUI) - to guide the review of O&G data quality. Between July and October 2013, we requested, collected, and assessed 5 categories of unconventional O&G data (wells drilled, violations, production, waste, and Class II disposal wells) from 10 states with active drilling activity. We based our assessment on eight data quality parameters (accessibility, usability, point location, completeness, metadata, agency responsiveness, accuracy, and cost). Using the DAUI, two authors graded the 10 states and then averaged their scores. The average score received across all states, data categories, and parameters was 67.1 out of 100, largely insufficient for proper data transparency. By state, Pennsylvania received the highest average ( = 93.5) and ranked first in all but one data category. The lowest scoring state was Texas ( = 44) largely due to its policy of charging for certain data. This article discusses the various reasons for scores received, as well as methodological limitations of the assessment metrics. We argue that the significant variability of unconventional O&G data-and its availability to the public-is a barrier to regulatory and industry transparency. The lack of transparency also impacts public education and broader participation in industry governance. This study supports the need to develop a set of data best management practices (BMPs) for state regulatory agencies and the O&G industry, and suggests potential BMPs for this purpose.

In situ one-step hydrothermal synthesis of oxygen-containing groups-modified g-C3N4 for the improved photocatalytic H2-evolution performance

NASA Astrophysics Data System (ADS)

Wu, Xinhe; Chen, Fengyun; Wang, Xuefei; Yu, Huogen

2018-01-01

Surface modification of g-C3N4 is one of the most effective strategies to boost its photocatalytic H2-evolution performance via promoting the interfacial catalytic reactions. In this study, an in situ one-step hydrothermal method was developed to prepare the oxygen-containing groups-modified g-C3N4 (OG/g-C3N4) by a facile and green hydrothermal treatment of bulk g-C3N4 in pure water without any additives. It was found that the hydrothermal treatment (180 °C) not only could greatly increase the specific surface area (from 2.3 to 69.8 m2 g-1), but also caused the formation of oxygen-containing groups (sbnd OH and Cdbnd O) on the OG/g-C3N4 surface, via the interlayer delamination and intralayer depolymerization of bulk g-C3N4. Photocatalytic experimental results indicated that after hydrothermal treatment, the resultant OG/g-C3N4 samples showed an obviously improved H2-evolution performance. Especially, when the hydrothermal time was 6 h, the resultant OG/g-C3N4(6 h) exhibited the highest photocatalytic activity, which was clearly higher than that of the bulk g-C3N4 by a factor of ca. 7. In addition to the higher specific surface area, the enhanced H2-evolution rate of OG/g-C3N4 photocatalysts can be mainly attributed to the formation of oxygen-containing groups, which possibly works as the effective H2-evolution active sites. Considering the facie and green synthesis method, the present work may provide a new insight for the development of highly efficient photocatalytic materials.

The Effects of a Concept Map-Based Information Display in an Electronic Portfolio System on Information Processing and Retention in a Fifth-Grade Science Class Covering the Earth's Atmosphere

ERIC Educational Resources Information Center

Kim, Paul; Olaciregui, Claudia

2008-01-01

An electronic portfolio system, designed to serve as a resource-based learning space, was tested in a fifth-grade science class. The control-group students accessed a traditional folder-based information display in the system and the experimental-group students accessed a concept map-based information display to review a science portfolio. The…

Baseline coastal oblique aerial photographs collected from Key Largo, Florida, to the Florida/Georgia border, September 5-6, 2014

USGS Publications Warehouse

Morgan, Karen L. M.

2015-09-14

In addition to the photographs, a Google Earth Keyhole Markup Language (KML) file is provided and can be used to view the images by clicking on the marker and then clicking on either the thumbnail or the link above the thumbnail. The KML files were created using the photographic navigation files. These KML files can be found in the kml folder.

Network Monitoring for Web-Based Threats

DTIC Science & Technology

2011-02-01

string to access files or folders that were not intended (see Figure 4-1). http://example.com/getUserProfile.jsp?item=../../../../etc/ passwd Figure...applied to vulnerable fields within a cookie (see Figure 4-2). Cookie: USER=1826cc8f:PSTYLE=../../../../etc/ passwd Figure 4-2: Path Traversal...further privileges. − For example, http://host/cgi- bin/lame.cgi?file=../../../../etc/ passwd • %00 requests − This is the hexadecimal value of a

11. Photocopy of photograph. Photographer unknown, circa 1955. Original photograph ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

11. Photocopy of photograph. Photographer unknown, circa 1955. Original photograph can be found in Marvine Colliery folder in the archives of the Lackawanna Historical Society, Scranton, Pennsylvania. VIEW SHOWING EAST AND NORTH FACADES OF BREAKER, WITH BOILER HOUSE AT FAR LEFT AND RETAIL SCALES OFFICE DIRECTLY EAST OF BREAKER, LOOKING SOUTHWEST - Marvine Colliery, Breaker No. 2, West side Boulevard Avenue, between East Parker Street & Route 380, Scranton, Lackawanna County, PA

40 CFR 420.104 - New source performance standards (NSPS).

Code of Federal Regulations, 2014 CFR

2014-07-01

... TSS 0.00125 0.000626 O&G 0.000522 0.000209 Chromium 1 0.0000209 0.0000084 Lead 0.0000094 0.0000031... pH (2) (2) 1 The limitations for chromium and nickel shall be applicable in lieu of those for lead... consecutive days Kg/kkg (pounds per 1,000 lb) of product TSS 0.00250 0.00125 O&G 0.00104 0.000417 Chromium 1 0...

40 CFR 420.104 - New source performance standards (NSPS).

Code of Federal Regulations, 2012 CFR

2012-07-01

... TSS 0.00125 0.000626 O&G 0.000522 0.000209 Chromium 1 0.0000209 0.0000084 Lead 0.0000094 0.0000031... pH (2) (2) 1 The limitations for chromium and nickel shall be applicable in lieu of those for lead... consecutive days Kg/kkg (pounds per 1,000 lb) of product TSS 0.00250 0.00125 O&G 0.00104 0.000417 Chromium 1 0...

40 CFR 420.104 - New source performance standards (NSPS).

Code of Federal Regulations, 2013 CFR

2013-07-01

... TSS 0.00125 0.000626 O&G 0.000522 0.000209 Chromium 1 0.0000209 0.0000084 Lead 0.0000094 0.0000031... pH (2) (2) 1 The limitations for chromium and nickel shall be applicable in lieu of those for lead... consecutive days Kg/kkg (pounds per 1,000 lb) of product TSS 0.00250 0.00125 O&G 0.00104 0.000417 Chromium 1 0...

40 CFR 437.43 - Effluent limitations attainable by the application of the best conventional pollutant control...

Code of Federal Regulations, 2010 CFR

2010-07-01

...&G, pH, and TSS are the same as the corresponding limitation specified in § 437.42(b). (c) Combined waste receipts from subparts A and B of this part: Limitations for O&G, pH, and TSS are the same as the... part: Limitations for BOD5, O&G, pH, and TSS are the same as the corresponding limitation specified in...

40 CFR 437.43 - Effluent limitations attainable by the application of the best conventional pollutant control...

Code of Federal Regulations, 2011 CFR

2011-07-01

...&G, pH, and TSS are the same as the corresponding limitation specified in § 437.42(b). (c) Combined waste receipts from subparts A and B of this part: Limitations for O&G, pH, and TSS are the same as the... part: Limitations for BOD5, O&G, pH, and TSS are the same as the corresponding limitation specified in...

40 CFR 420.104 - New source performance standards (NSPS).

Code of Federal Regulations, 2011 CFR

2011-07-01

... TSS 0.00125 0.000626 O&G 0.000522 0.000209 Chromium 1 0.0000209 0.0000084 Lead 0.0000094 0.0000031... pH (2) (2) 1 The limitations for chromium and nickel shall be applicable in lieu of those for lead... consecutive days Kg/kkg (pounds per 1,000 lb) of product TSS 0.00250 0.00125 O&G 0.00104 0.000417 Chromium 1 0...

40 CFR 420.104 - New source performance standards (NSPS).

Code of Federal Regulations, 2010 CFR

2010-07-01

... TSS 0.00125 0.000626 O&G 0.000522 0.000209 Chromium 1 0.0000209 0.0000084 Lead 0.0000094 0.0000031... pH (2) (2) 1 The limitations for chromium and nickel shall be applicable in lieu of those for lead... consecutive days Kg/kkg (pounds per 1,000 lb) of product TSS 0.00250 0.00125 O&G 0.00104 0.000417 Chromium 1 0...

Schwannoma-like tumor in the anterior cranial fossa immunonegative for Leu7 but immunopositive for Schwann/2E.

PubMed

Bohoun, Christian Aïssè; Terakawa, Yuzo; Goto, Takeo; Tanaka, Sayaka; Kuwae, Yuko; Ohsawa, Masahiko; Morisako, Hiroki; Nakajo, Kosuke; Sato, Hidetoshi; Ohata, Kenji; Yokoo, Hideaki

2017-06-01

Schwannoma arising from the olfactory system, often called olfactory groove schwannoma (OGS), is rare, as the olfactory bulb and tract, belonging to the central nervous system, should lack Schwann cells. Another rare entity called olfactory ensheathing cell tumor (OECT) has been reported, which mimics clinical and radiological characteristics of OGS. Here, we report two rare cases of schwannoma-like tumor in the anterior cranial fossa that showed negative staining for Leu7, but positive staining for Schwann/2E, and discuss their origin. Two cases of mass lesions in the anterior cranial fossa in a 26-year-old man and a 24-year-old woman were successfully removed. Morphological examination of these tumors was compatible with a diagnosis of schwannoma. Immunohistochemically, both cases were negative for Leu7, yielding a diagnosis of OECT, but were positive for the schwannoma-specific marker, Schwann/2E. Immunohistochemical staining results in our two cases question the current assumption that OGS and OECT can be distinguished only by Leu7 staining pattern. In conclusion, the origins of OGS and OECT remain to be determined, and further studies in larger numbers of cases are needed to characterize these rare tumors in the anterior cranial fossa. © 2016 Japanese Society of Neuropathology.

α decay properties of 296Og within the two-potential approach

NASA Astrophysics Data System (ADS)

Deng, Jun-Gang; Zhao, Jie-Cheng; Chen, Jiu-Long; Wu, Xi-Jun; Li, Xiao-Hua

2018-04-01

The present work is a continuation of our previous paper [J.-G. Deng, et al., Chin. Phys. C, 41: 124109 (2017)]. In the present work, the α decay half-life of the unknown nucleus 296Og is predicted within the two-potential approach and the hindrance factors of all 20 even-even nuclei in the same region as 296Og, i.e. proton number 82

Requirement for Pectin Methyl Esterase and Preference for Fragmented over Native Pectins for Wall-associated Kinase-activated, EDS1/PAD4-dependent Stress Response in Arabidopsis*

PubMed Central

Kohorn, Bruce D.; Kohorn, Susan L.; Saba, Nicholas J.; Martinez, Victoriano Meco

2014-01-01

The wall-associated kinases (WAKs) have a cytoplasmic protein kinase domain that spans the plasma membrane and binds pectin in the extracellular matrix of plants. WAKs are required for cell expansion during Arabidopsis seedling development but are also an integral part of the response to pathogens and stress that present oligogalacturonides (OGs), which subsequently bind to WAKs and activate a MPK6 (mitogen-activated protein kinase)-dependent pathway. It was unclear how WAKs distinguish native pectin polymers and OGs to activate one or the other of these two pathways. A dominant allele of WAK2 constitutively activates the stress response, and we show here that the effect is dependent upon EDS1 and PAD4, transcriptional activators involved in the pathogen response. Moreover, the WAK2 dominant allele is suppressed by a null allele of a pectin methyl esterase (PME3) whose activity normally leads to cross-linking of pectins in the cell wall. Although OGs activate a transcriptional response in wild type, the response is enhanced in a pme3/pme3 null, consistent with a competition by OG and native polymers for activation of WAKs. This provides a plausible mechanism for WAKs to distinguish an expansion from a stress pathway. PMID:24855660

Residential noise from nearby oil and gas well construction and drilling.

PubMed

Blair, Benjamin D; Brindley, Stephen; Dinkeloo, Eero; McKenzie, Lisa M; Adgate, John L

2018-05-11

Public concern about oil and gas (O&G) operations in residential areas is substantial. Noise from construction and drilling related to O&G operations may be greater than other phases of O&G operations; yet the impacts of audible and low-frequency noise during these operations are not extensively explored nor the effects on health well understood. This study documents the noise levels at a multi-well O&G well pad during construction and drilling in a residential area in Colorado. A-weighted (dBA) and C-weighted (dBC) noise measurements were collected at four locations during development over a 3-month period. The maximum 1-min equivalent continuous sound levels over a 1-month period were 60.2 dBA and 80.0 dBC. Overall, 41.1% of daytime and 23.6% of nighttime dBA 1-min equivalent continuous noise measurements were found to exceed 50 dBA, and 97.5% of daytime and 98.3% of nighttime measurements were found to exceed 60 dBC. Noise levels exceeding 50 dBA or 60 dBC may cause annoyance and be detrimental to health; thus, these noise levels have the potential to impact health and noise levels and associated health effects warrant further investigation.

Accuracy of Three-Dimensional Planning in Surgery-First Orthognathic Surgery: Planning Versus Outcome.

PubMed

Tran, Ngoc Hieu; Tantidhnazet, Syrina; Raocharernporn, Somchart; Kiattavornchareon, Sirichai; Pairuchvej, Verasak; Wongsirichat, Natthamet

2018-05-01

The benefit of computer-assisted planning in orthognathic surgery (OGS) has been extensively documented over the last decade. This study aimed to evaluate the accuracy of three-dimensional (3D) virtual planning in surgery-first OGS. Fifteen patients with skeletal class III malocclusion who underwent bimaxillary OGS with surgery-first approach were included. A composite skull model was reconstructed using data from cone-beam computed tomography and stereolithography from a scanned dental cast. Surgical procedures were simulated using Simplant O&O software, and the virtual plan was transferred to the operation room using 3D-printed splints. Differences of the 3D measurements between the virtual plan and postoperative results were evaluated, and the accuracy was reported using root mean square deviation (RMSD) and the Bland-Altman method. The virtual planning was successfully transferred to surgery. The overall mean linear difference was 0.88 mm (0.79 mm for the maxilla and 1 mm for the mandible), and the overall mean angular difference was 1.16°. The RMSD ranged from 0.86 to 1.46 mm and 1.27° to 1.45°, within the acceptable clinical criteria. In this study, virtual surgical planning and 3D-printed surgical splints facilitated the diagnosis and treatment planning, and offered an accurate outcome in surgery-first OGS.

Development of cereal-based functional food using cereal-mix substrate fermented with probiotic strain - Pichia kudriavzevii OG32.

PubMed

Ogunremi, Omotade R; Agrawal, Renu; Sanni, Abiodun I

2015-11-01

Probiotic strains contribute to the functionality of foods during fermentation. In this present work, cereal-mix was fermented with probiotic Pichia kudriavzevii OG32. Selected fermentation parameters and functional properties of the product were determined. The growth of Pichia kudriavzevii OG32 was supported by the cereal-mix containing 1% salt and 0.2% red chili powder to counts of between 7.46 and 8.22 Log10 cfu/mL within 24 h. Pichia kudriavzevii OG32 increased the viscosity of cereal-mix with the highest inoculum size (1.84x105cfu/ml) giving the highest viscosity of 1793.6 mPa.S. An inoculum size of 1.98 × 10(4) cfu/mL gave the most acceptable product based on the sensory evaluation by the panelist. Forty volatile compounds were identified in the fermented product, while acids (32.21%) and esters (32.37%) accounted for the largest proportions. The cereal-based fermented product scavenged DPPH from 200 μmol/L methanolic solution by 55.71%. Probiotic yeast improved the sensory and some functional properties of cereal-based substrate during fermentation. This is one of the first reports on the volatile composition of cereal-based functional food produced with probiotic yeast.

Studies on pulsed optogalvanic effect in Eu/Ne hollow cathode discharge.

PubMed

Saini, V K; Kumar, P; Dixit, S K; Nakhe, S V

2014-07-01

The optogalvanic (OG) effect has been observed in a Eu/Ne hollow cathode discharge lamp using pulsed laser irradiation. An OG spectrum is recorded in dye laser wavelength region 574–602 nm using a boxcar-averager. In total 41 atomic lines are observed. Of these, 38 lines are assigned to neon transitions. Two lines observed corresponding to wavelengths 576.519 and 601.815 nm are assigned to europium transitions; (4f 7 6s 2 , S 8 7/2 →4f 7 6s6p , zP 6 7/2 ) and (4f 7 6s 2 , S 8 7/2 →4f 7 6s6p , zP 8 9/2 ), respectively, and the remaining line at 582.475 nm could not be assigned. The effect of the discharge current on europium as well as neon OG signals is also studied. At moderate discharge current values, an extra positive peak is observed in neon OG signal for the transition (1s 5 →2p 2 ) at 588.189 nm, which is explained by Penning-ionization process using the quasi-resonant energy transfer interactions between excited neon and europium atoms lying in 2p 2 and D 10 9/2 states, respectively.

40 CFR 420.102 - Effluent limitations representing the degree of effluent reduction attainable by the application...

Code of Federal Regulations, 2014 CFR

2014-07-01

....000626 O&G 0.000522 0.000209 Chromium 1 0.0000209 0.0000084 Lead 0.0000094 0.0000031 Nickel 1 0.0000188 0... limitations for chromium and nickel shall be applicable in lieu of those for lead and zinc when cold rolling...) of product TSS 0.00626 0.00313 O&G 0.00261 0.00104 Chromium 1 0.000104 0.0000418 Lead 0.0000469 0...

40 CFR 420.102 - Effluent limitations representing the degree of effluent reduction attainable by the application...

Code of Federal Regulations, 2013 CFR

2013-07-01

....000626 O&G 0.000522 0.000209 Chromium 1 0.0000209 0.0000084 Lead 0.0000094 0.0000031 Nickel 1 0.0000188 0... limitations for chromium and nickel shall be applicable in lieu of those for lead and zinc when cold rolling...) of product TSS 0.00626 0.00313 O&G 0.00261 0.00104 Chromium 1 0.000104 0.0000418 Lead 0.0000469 0...

40 CFR 420.102 - Effluent limitations representing the degree of effluent reduction attainable by the application...

Code of Federal Regulations, 2012 CFR

2012-07-01

....000626 O&G 0.000522 0.000209 Chromium 1 0.0000209 0.0000084 Lead 0.0000094 0.0000031 Nickel 1 0.0000188 0... limitations for chromium and nickel shall be applicable in lieu of those for lead and zinc when cold rolling...) of product TSS 0.00626 0.00313 O&G 0.00261 0.00104 Chromium 1 0.000104 0.0000418 Lead 0.0000469 0...

40 CFR 420.102 - Effluent limitations representing the degree of effluent reduction attainable by the application...

Code of Federal Regulations, 2010 CFR

2010-07-01

....000626 O&G 0.000522 0.000209 Chromium 1 0.0000209 0.0000084 Lead 0.0000094 0.0000031 Nickel 1 0.0000188 0... limitations for chromium and nickel shall be applicable in lieu of those for lead and zinc when cold rolling...) of product TSS 0.00626 0.00313 O&G 0.00261 0.00104 Chromium 1 0.000104 0.0000418 Lead 0.0000469 0...

40 CFR 420.102 - Effluent limitations representing the degree of effluent reduction attainable by the application...

Code of Federal Regulations, 2011 CFR

2011-07-01

....000626 O&G 0.000522 0.000209 Chromium 1 0.0000209 0.0000084 Lead 0.0000094 0.0000031 Nickel 1 0.0000188 0... limitations for chromium and nickel shall be applicable in lieu of those for lead and zinc when cold rolling...) of product TSS 0.00626 0.00313 O&G 0.00261 0.00104 Chromium 1 0.000104 0.0000418 Lead 0.0000469 0...

Sustainable oil and grease removal from synthetic stormwater runoff using bench-scale bioretention studies.

PubMed

Hong, Eunyoung; Seagren, Eric A; Davis, Allen P

2006-02-01

One of the principal components of the contaminant load in urban stormwater runoff is oil and grease (O&G) pollution, resulting from vehicle emissions. A mulch layer was used as a contaminant trap to remove O&G (dissolved and particulate-associated naphthalene, dissolved toluene, and dissolved motor oil hydrocarbons) from a synthetic runoff during a bench-scale infiltration study. Approximately 80 to 95% removal of all contaminants from synthetic runoff was found via sorption and filtration. Subsequently, approximately 90% of the sorbed naphthalene, toluene, oil, and particulate-associated naphthalene was biodegraded within approximately 3, 4, 8, and 2 days after the event, respectively, based on decreases in contaminant concentrations coupled with increases of microbial populations. These results indicate the effectiveness and sustainability of placing a thin layer of mulch on the surface of a bioretention facility for reducing O&G pollution from urban stormwater runoff.

Geographical Analysis of Conflict Minerals Utilizing Laser-Induced Breakdown Spectroscopy

DTIC Science & Technology

2012-01-01

boundaries are not formulated on the basis of geology . The results were slightly better when the putative mineral type (i.e. columbite or tantalite) is...textural and/or chemical heterogeneity within and be- tween samples from a single deposit. The role of geology in assuring a meaningful classification...for the Transfer of Knowledge — Research Scholarship 43644 to K.S.D. The authors wish to thank Peter Torrione of New Folder Consulting, Durham, NC for

Gulf War Air Power Survey. Volume 5. A Statistical Compendium and Chronology

DTIC Science & Technology

1993-01-01

documentation proved to be a blessing and a curse. While students and analysts of the Gulf War can tap an especially broad spectrum of information collected...to target folders and pre- and post-strike photos. They include interviews and oral history materials, SITREPS from several different Services and...these limits. You will note the first "day" lasted longer than one day and included two nights. Subsequently, the system stabilized according to a

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

Once installed, the 'HindCast Player' HyperCard stack displays the spill trajectory of the EXXON Valdez oil spill in the Prince William Sound in March of 1989. The product, 'Exxon Valdez Hind Cast' contains one compressed file and one documentation file. The file containing the documentation is named 'Read.me', and the compressed file is named Exxon HindCasts'. The compressed folder contains a moov file called 'EXXON Valdez', a HyperCard Stack called, 'HindCast Player v/2', and Apples QuickTime(TM) extension file.

Model Analyst’s Toolkit User Guide, Version 7.1.0

DTIC Science & Technology

2015-08-01

Help > About)  Environment details ( operating system )  metronome.log file, located in your MAT 7.1.0 installation folder  Any log file that...requirements to run the Model Analyst’s Toolkit:  Windows XP operating system (or higher) with Service Pack 2 and all critical Windows updates installed...application icon on your desktop  Create a Quick Launch icon – Creates a MAT application icon on the taskbar for operating systems released

Digitizing an Analog Radiography Teaching File Under Time Constraint: Trade-Offs in Efficiency and Image Quality.

PubMed

Loehfelm, Thomas W; Prater, Adam B; Debebe, Tequam; Sekhar, Aarti K

2017-02-01

We digitized the radiography teaching file at Black Lion Hospital (Addis Ababa, Ethiopia) during a recent trip, using a standard digital camera and a fluorescent light box. Our goal was to photograph every radiograph in the existing library while optimizing the final image size to the maximum resolution of a high quality tablet computer, preserving the contrast resolution of the radiographs, and minimizing total library file size. A secondary important goal was to minimize the cost and time required to take and process the images. Three workers were able to efficiently remove the radiographs from their storage folders, hang them on the light box, operate the camera, catalog the image, and repack the radiographs back to the storage folder. Zoom, focal length, and film speed were fixed, while aperture and shutter speed were manually adjusted for each image, allowing for efficiency and flexibility in image acquisition. Keeping zoom and focal length fixed, which kept the view box at the same relative position in all of the images acquired during a single photography session, allowed unused space to be batch-cropped, saving considerable time in post-processing, at the expense of final image resolution. We present an analysis of the trade-offs in workflow efficiency and final image quality, and demonstrate that a few people with minimal equipment can efficiently digitize a teaching file library.

Physiochemical Characterization of Iodine (V) Oxide: Hydration Rates

DTIC Science & Technology

2014-12-15

decomposition .21 2 Distribution A Scheme 1. Iodine (V) Oxide‐Water System Hydration : 3I2O5(s) + H2O(g) → 2HI3O8(s) + 2H2O(g) → 6HIO3(s...dehydration steps and decomposition step for each sample. The corresponding percent compositions of the three hydration forms of the oxide have been...135 Physiochemical Characterization of Iodine (V) Oxide: Hydration Rates Distribution A: Approved for public release; distribution unlimited

Comparison of Oogenesis and Sex Steroid Profiles between Twice and Once Annually Spawning of Rainbow Trout Females (Oncorhynchus mykiss)

PubMed Central

Estay, Francisco; Colihueque, Nelson; Araneda, Cristian

2012-01-01

This study compares the gonadosomatic index (GSI), oocyte growth (OG), gonadal histology, and plasma level concentrations of sex hormones (estradiol-17β (E2) and vitellogenin (V)) of twice-spawning (T-SP) and once-spawning (O-SP) females of rainbow trout throughout the additional and the normal reproductive cycle, respectively. In T-SP, the GSI values rapidly increase from May to November, in contrast to O-SP, which showed low and constant GSI values (1.19 to 14.5 and 1.19 to 0.63, resp.). T-SP exhibited a marked increase of OG in the same period, reaching a maximum diameter of 4,900 ± 141.42 μm, in contrast to O-SP, which presented a slow OG. The gonadal histology of T-SP agreed with the general pattern of ovogenesis observed for O-SP (vitellogenesis, ovulation, and recrudescence); however, this process was nonsynchronous between the two breeder groups. Plasma steroid levels showed significant variation during oogenesis, which agreed with the GSI, OG, and gonadal histology patterns. The level of E2 increased to a maximum value of 26.2 ng/mL and 36.0 ng/mL in O-SP and T-SP, respectively, one or two months before the spawning event where vitellogenesis was fully active. The V concentrations followed a pattern similar to those of E2. PMID:23213308

Telecom and scintillation first data analysis for DOMINO: laser communication between SOTA, onboard SOCRATES satellite, and MEO optical ground station

NASA Astrophysics Data System (ADS)

Phung, D.-H.; Samain, E.; Maurice, N.; Albanesse, D.; Mariey, H.; Aimar, M.; M. Lagarde, G.; Artaud, G.; Issler, J.-L.; Vedrenne, N.; Velluet, M.-T.; Toyoshima, M.; Akioka, M.; Kolev, D.; Munemasa, Y.; Takenaka, H.; Iwakiri, N.

2016-03-01

In collaboration between CNES, NICT, Geoazur, the first successful lasercom link between the micro-satellite SOCRATES and an OGS in Europe has been established. This paper presents some results of telecom and scintillation first data analysis for 4 successful links in June & July 2015 between SOTA terminal and MEO optical ground station (OGS) at Caussols France. The telecom and scintillation data have been continuously recorded during the passes by using a detector developed at the laboratory. An irradiance of 190 nW/m2 and 430 nW/m2 has been detected for 1549 nm and 976 nm downlinks at 35° elevation. Spectrums of power fluctuation measured at OGS are analyzed at different elevation angles and at different diameters of telescope aperture to determine fluctuations caused by pointing error (due to satellite & OGS telescope vibrations) and caused by atmospheric turbulence. Downlink & Uplink budgets are analyzed, the theoretical estimation matches well to measured power levels. Telecom signal forms and bit error rates (BER) of 1549 nm and 976 nm downlink are also shown at different diameters of telescope aperture. BER is 'Error Free' with full-aperture 1.5m telescope, and almost in `good channel' with 0.4 m sub-aperture of telescope. We also show the comparison between the expected and measured BER distributions.

Immunomodulatory Role of Ocimum gratissimum and Ascorbic Acid against Nicotine-Induced Murine Peritoneal Macrophages In Vitro

PubMed Central

Mahapatra, Santanu Kar; Chakraborty, Subhankari Prasad; Roy, Somenath

2011-01-01

The aim of this present study was to evaluate the immune functions and immune responses in nicotine-induced (10 mM) macrophages and concurrently establish the immunomodulatory role of aqueous extract of Ocimum gratissimum (Ae-Og) and ascorbic acid. In this study, nitrite generations and some phenotype functions by macrophages were studied. Beside that, release of Th1 cytokines (TNF-α, IL-12) and Th2 cytokines (IL-10, TGF-β) was measured by ELISA, and the expression of these cytokines at mRNA level was analyzed by real-time PCR. Ae-Og, at a dose of 10 μg/mL, significantly reduced the nicotine-induced NO generation and iNOSII expression. Similar kinds of response were observed with supplementation of ascorbic acid (0.01 mM). The administration of Ae-Og and ascorbic acid increased the decreased adherence, chemotaxis, phagocytosis, and intracellular killing of bacteria in nicotine-treated macrophages. Ae-Og and ascorbic acid were found to protect the murine peritoneal macrophages through downregulation of Th1 cytokines in nicotine-treated macrophages with concurrent activation of Th2 responses. These findings strongly enhanced our understanding of the molecular mechanism leading to nicotine-induced suppression of immune functions and provide additional rationale for application of anti-inflammatory therapeutic approaches by O. gratissimum and ascorbic acid for different inflammatory disease prevention and treatment during nicotine toxicity. PMID:22220218

Requirement for pectin methyl esterase and preference for fragmented over native pectins for wall-associated kinase-activated, EDS1/PAD4-dependent stress response in Arabidopsis.

PubMed

Kohorn, Bruce D; Kohorn, Susan L; Saba, Nicholas J; Martinez, Victoriano Meco

2014-07-04

The wall-associated kinases (WAKs) have a cytoplasmic protein kinase domain that spans the plasma membrane and binds pectin in the extracellular matrix of plants. WAKs are required for cell expansion during Arabidopsis seedling development but are also an integral part of the response to pathogens and stress that present oligogalacturonides (OGs), which subsequently bind to WAKs and activate a MPK6 (mitogen-activated protein kinase)-dependent pathway. It was unclear how WAKs distinguish native pectin polymers and OGs to activate one or the other of these two pathways. A dominant allele of WAK2 constitutively activates the stress response, and we show here that the effect is dependent upon EDS1 and PAD4, transcriptional activators involved in the pathogen response. Moreover, the WAK2 dominant allele is suppressed by a null allele of a pectin methyl esterase (PME3) whose activity normally leads to cross-linking of pectins in the cell wall. Although OGs activate a transcriptional response in wild type, the response is enhanced in a pme3/pme3 null, consistent with a competition by OG and native polymers for activation of WAKs. This provides a plausible mechanism for WAKs to distinguish an expansion from a stress pathway. © 2014 by The American Society for Biochemistry and Molecular Biology, Inc.

Sequential capillary electrophoresis analysis using optically gated sample injection and UV/vis detection.

PubMed

Liu, Xiaoxia; Tian, Miaomiao; Camara, Mohamed Amara; Guo, Liping; Yang, Li

2015-10-01

We present sequential CE analysis of amino acids and L-asparaginase-catalyzed enzyme reaction, by combing the on-line derivatization, optically gated (OG) injection and commercial-available UV-Vis detection. Various experimental conditions for sequential OG-UV/vis CE analysis were investigated and optimized by analyzing a standard mixture of amino acids. High reproducibility of the sequential CE analysis was demonstrated with RSD values (n = 20) of 2.23, 2.57, and 0.70% for peak heights, peak areas, and migration times, respectively, and the LOD of 5.0 μM (for asparagine) and 2.0 μM (for aspartic acid) were obtained. With the application of the OG-UV/vis CE analysis, sequential online CE enzyme assay of L-asparaginase-catalyzed enzyme reaction was carried out by automatically and continuously monitoring the substrate consumption and the product formation every 12 s from the beginning to the end of the reaction. The Michaelis constants for the reaction were obtained and were found to be in good agreement with the results of traditional off-line enzyme assays. The study demonstrated the feasibility and reliability of integrating the OG injection with UV/vis detection for sequential online CE analysis, which could be of potential value for online monitoring various chemical reaction and bioprocesses. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Accuracy of Three-Dimensional Planning in Surgery-First Orthognathic Surgery: Planning Versus Outcome

PubMed Central

Tran, Ngoc Hieu; Tantidhnazet, Syrina; Raocharernporn, Somchart; Kiattavornchareon, Sirichai; Pairuchvej, Verasak; Wongsirichat, Natthamet

2018-01-01

Background The benefit of computer-assisted planning in orthognathic surgery (OGS) has been extensively documented over the last decade. This study aimed to evaluate the accuracy of three-dimensional (3D) virtual planning in surgery-first OGS. Methods Fifteen patients with skeletal class III malocclusion who underwent bimaxillary OGS with surgery-first approach were included. A composite skull model was reconstructed using data from cone-beam computed tomography and stereolithography from a scanned dental cast. Surgical procedures were simulated using Simplant O&O software, and the virtual plan was transferred to the operation room using 3D-printed splints. Differences of the 3D measurements between the virtual plan and postoperative results were evaluated, and the accuracy was reported using root mean square deviation (RMSD) and the Bland-Altman method. Results The virtual planning was successfully transferred to surgery. The overall mean linear difference was 0.88 mm (0.79 mm for the maxilla and 1 mm for the mandible), and the overall mean angular difference was 1.16°. The RMSD ranged from 0.86 to 1.46 mm and 1.27° to 1.45°, within the acceptable clinical criteria. Conclusion In this study, virtual surgical planning and 3D-printed surgical splints facilitated the diagnosis and treatment planning, and offered an accurate outcome in surgery-first OGS. PMID:29581806

Phylogeny Inference of Closely Related Bacterial Genomes: Combining the Features of Both Overlapping Genes and Collinear Genomic Regions

PubMed Central

Zhang, Yan-Cong; Lin, Kui

2015-01-01

Overlapping genes (OGs) represent one type of widespread genomic feature in bacterial genomes and have been used as rare genomic markers in phylogeny inference of closely related bacterial species. However, the inference may experience a decrease in performance for phylogenomic analysis of too closely or too distantly related genomes. Another drawback of OGs as phylogenetic markers is that they usually take little account of the effects of genomic rearrangement on the similarity estimation, such as intra-chromosome/genome translocations, horizontal gene transfer, and gene losses. To explore such effects on the accuracy of phylogeny reconstruction, we combine phylogenetic signals of OGs with collinear genomic regions, here called locally collinear blocks (LCBs). By putting these together, we refine our previous metric of pairwise similarity between two closely related bacterial genomes. As a case study, we used this new method to reconstruct the phylogenies of 88 Enterobacteriale genomes of the class Gammaproteobacteria. Our results demonstrated that the topological accuracy of the inferred phylogeny was improved when both OGs and LCBs were simultaneously considered, suggesting that combining these two phylogenetic markers may reduce, to some extent, the influence of gene loss on phylogeny inference. Such phylogenomic studies, we believe, will help us to explore a more effective approach to increasing the robustness of phylogeny reconstruction of closely related bacterial organisms. PMID:26715828

The interns' learning assessment in obstetrics and gynecology department of Zahedan University of Medical Sciences.

PubMed

Roudbari, Masoud; Yaghmaei, Minoo

2007-09-01

One of the aims of management priorities in medical universities is the evaluation of learning in educational departments in order to prevent educational retardation and to improve the quality of education. The aim of this study was to evaluate the interns' learning in the obstetrics and gynecology (O&G) department at Zahedan University of Medical Sciences (ZUMS). The study was performed in ZUMS, Iran, in 2002-2003 on all interns at the O&G department, including 30 men and 40 women. For data collection, a questionnaire was used and included some questions regarding the common emergencies and diseases in O&G, together with different learning indicators such as reading, observation, hearing, management, and the capability of management. The data were analyzed using descriptive statistics, tables, t test, and chi-square test using the SPSS software. The mean percentages of learning indicators of observation, bedside teaching, supervised management, and personal management in the common emergencies and diseases of O&G in male interns were significantly lower than those in female interns. Also, the mean percentages of managing capabilities were 12% and 70.5% in common emergencies and 14.2% and 59.3% in common diseases for male and female interns, respectively. The chi-square test showed a significant difference between the mean percentages of the managing capabilities in male and female interns for the majority of the common emergencies and diseases. Also, the chi-square test revealed a significant relationship between the learning indicators and the interns' managing capabilities for common emergencies and diseases. Some learning indicators in the male interns were very low. This needs urgent improvement of the learning quality in the O&G department, especially for the male interns, particularly those who are supposed to work in the deprived areas of the country after graduation in the public service.

Environmental Defense Fund Oil and Gas Methane Studies: Principles for Collaborating with Industry Partners while Maintaining Scientific Objectivity

NASA Astrophysics Data System (ADS)

Hamburg, S.

2016-12-01

Environmental Defense Fund (EDF) launched a series of 16 research studies in 2012 to quantify methane emissions from the U.S. oil and gas (O&G) supply chain. In addition to EDF's funding from philanthropic individuals and foundations and in-kind contributions from universities, over forty O&G companies contributed money to the studies. For a subset of studies that required partner companies to provide site access to measure their equipment, five common principles were followed to assure that research was objective and scientifically rigorous. First, academic scientists were selected as principal investigators (PIs) to lead the studies. In line with EDF's policy of not accepting money from corporate partners, O&G companies provided funding directly to academic PIs. Technical work groups and steering committees consisting of EDF and O&G partner staff advised the PIs in the planning and implementation of research, but PIs had the final authority in scientific decisions including publication content. Second, scientific advisory panels of independent experts advised the PIs in the study design, data analysis, and interpretation. Third, studies employed multiple methodologies when possible, including top-down and bottom-up measurements. This helped overcome the limitations of individual approaches to decrease the uncertainty of emission estimates and minimize concerns with data being "cherry-picked". Fourth, studies were published in peer-reviewed journals to undergo an additional round of independent review. Fifth, transparency of data was paramount. Study data were released after publication, although operator and site names of individual data points were anonymized to ensure transparency and allow independent analysis. Following these principles allowed an environmental organization, O&G companies, and academic scientists to collaborate in scientific research while minimizing conflicts of interest. This approach can serve as a model for a scientifically rigorous process minimally influenced by study partners.

Integrated processes for produced water polishing: Enhanced flotation/sedimentation combined with advanced oxidation processes.

PubMed

Jiménez, Silvia; Micó, María M; Arnaldos, Marina; Ferrero, Enrique; Malfeito, Jorge J; Medina, Francisco; Contreras, Sandra

2017-02-01

In this study, bench scale dissolved air flotation (DAF) and settling processes have been studied and compared to a novel flotation technology based on the use of glass microspheres of limited buoyancy and its combination with conventional DAF, (Enhanced DAF or E-DAF). They were evaluated as pretreatments for advanced oxidation processes (AOPs) to polish produced water (PW) for reuse purposes. Settling and E-DAF without air injection showed adequate turbidity and oil and grease (O&G) removals, with eliminations higher than 87% and 90% respectively, employing 70 mg L -1 of FeCl 3 and 83 min of settling time, and 57.9 mg L -1 of FeCl 3 , 300 mg L -1 of microspheres and a flocculation rate of 40 rpm in the E-DAF process. A linear correlation was observed between final O&G concentration and turbidity after E-DAF. In order to polish the O&G content of the effluent even further, to remove soluble compounds as phenol and to take advantage of residual iron after these treatments, Fenton and photo-Fenton reactions were essayed. After 6 h of the Fenton reaction at pH 3, the addition of 1660 mg L -1 of H 2 O 2 and 133 mg L -1 of iron showed a maximum O&G elimination of 57.6% and a phenol removal up to 80%. Photo-Fenton process showed better results after 3 h, adding 600 mg L -1 of H 2 O 2 and 300 mg L -1 of iron, at pH 3, with a higher fraction of elimination of the O&G content (73.7%) and phenol (95%) compared to the conventional Fenton process. Copyright © 2016 Elsevier Ltd. All rights reserved.

Antimicrobial Efficacy of a Silver Impregnated Hydrophilic PU Foam.

PubMed

Percival, Steven L

2018-06-01

A novel hydrophilic polyurethane (PU) foam dressing which is impregnated with silver chloride, Optifoam® Gentle (OG) Ag+ (Medline Industries Inc., Chicago, Illinois), was evaluated in this study. The aims of this study were to determine the rate of elution of silver from the foam dressing over a period of 168 hours into simulated wound fluid and an evaluation of antimicrobial efficacy using zone of inhibition (ZOI), direct kill, and time-kill viability. Thirty-two microorganisms associated with wounds including Pseudomonas aeruginosa, Methicillin sensitive Staphylococcus aureus (MSSA), Acinetobacter baumannii, Candida albicans, and antibiotic-resistant strains (Methicillin-resistant S. aureus [MRSA] and Vancomycin-resistant Enterococci [VRE]) were evaluated. Silver release from the wound dressing showed an exponential curve with a stable sustained release of 25ppm achieved after 24 hours, which was maintained for the full duration of the study. OG Ag+ caused inhibition zones ranging from 4-16mm after a 24-hour contact time. In the direct kill assay, OG Ag+ reduced the microbial numbers below the limit of detection and reduced viability by a log of four within 24 hours. For the time-kill viability studies, the results support the use of this hydrophilic polyurethane foam as a wound dressing for use in wounds at risk of infection or infected by achieving a four log kill within six hours and a six log kill in 16 hours. In conclusion, OG Ag+ was shown to be an effective wound dressing in the killing of a range of important opportunistic pathogens of relevance to wound healing and infections. Achieving a six log kill against S. aureus and E.coli, within 16 hours in the time kill assay, (ASTM E2315-03) demonstrates that OG Ag+ should be an important addition to the armoury available for the management of acute and chronic wounds at risk of infection or clinically infected.

A Model-Based Analysis of Semi-Automated Data Discovery and Entry Using Automated Content Extraction

DTIC Science & Technology

2011-02-01

Accomplish Goal) to (a) visually search the contents of a file folder until the icon corresponding to the desired file is located (Choose...Item_from_set), and (b) move the mouse to that icon and double click to open it (Double_select Object). Note that Choose Item_from_set and Double_select...argument, which Open File fills with <found_item>, a working memory pointer to the file icon that Choose_item_from Set finds. Look_at, Point_to

Arkansas and Louisiana Aeromagnetic and Gravity Maps and Data - A Website for Distribution of Data

USGS Publications Warehouse

Bankey, Viki; Daniels, David L.

2008-01-01

This report contains digital data, image files, and text files describing data formats for aeromagnetic and gravity data used to compile the State aeromagnetic and gravity maps of Arkansas and Louisiana. The digital files include grids, images, ArcInfo, and Geosoft compatible files. In some of the data folders, ASCII files with the extension 'txt' describe the format and contents of the data files. Read the 'txt' files before using the data files.

Photographic copy of 8” x 10” black and white photograph ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Photographic copy of 8” x 10” black and white photograph of photograph of Franklin M. Masters (1883–1974). Photographer unknown: Loose in separate folder in oversized box located at the National Museum of American History, Smithsonian Institution, Archives Center, Work and Industry Division, Washington, D.C. PHOTOGRAPH OF FRANKLIN M. MASTERS (1883-1974). - Huey P. Long Bridge, Spanning Mississippi River approximately midway between nine & twelve mile points upstream from & west of New Orleans, Jefferson, Jefferson Parish, LA

Photographic copy of 8” x 10” black and white photograph ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Photographic copy of 8” x 10” black and white photograph of photograph of Ralph Modjeski (1861–1940). Photographer unknown: Loose in separate folder in oversized box located at the National Museum of American History, Smithsonian Institution, Archives Center, Work and Industry Division, Washington, D.C. PHOTOGRAPH OF RALPH MODJESKI (1861 - 1940). - Huey P. Long Bridge, Spanning Mississippi River approximately midway between nine & twelve mile points upstream from & west of New Orleans, Jefferson, Jefferson Parish, LA

Significant Metalliferous and Selected Non-Metalliferous Lode Deposits, and Selected Placer Districts of Northeast Asia

USGS Publications Warehouse

Ariunbileg, Sodov; Biryul'kin, Gennandiy V.; Byamba, Jamba; Davydov, Yury V.; Dejidmaa, Gunchin; Distanov, Elimir G.; Dorjgotov, Dangindorjiin; Gamyanin, Gennadiy N.; Gerel, Ochir; Fridovskiy, Valeriy Y.; Gotovsuren, Ayurzana; Hwang, Duk-Hwan; Kochnev, Anatoliy P.; Kostin, Alexei V.; Kuzmin, Mikhail I.; Letunov, Sergey A.; Jiliang, Li; Xujun, Li; Malceva, Galina D.; Melnikov, V.D.; Nikitin, Valeriy; Obolenskiy, Alexander A.; Ogasawara, Masatsugu; Orolmaa, Demberel; Parfenov, Leonid M.; Popov, Nikolay V.; Prokopiev, Andrei V.; Ratkin, Vladimir; Rodionov, Sergey M.; Seminskiy, Zhan V.; Shpikerman, Vladimir I.; Smelov, Alexander P.; Sotnikov, Vitaly I.; Spiridonov, Alexander V.; Stogniy, Valeriy V.; Sudo, Sadahisa; Fengyue, Sun; Jiapeng, Sun; Weizhi, Sun; Supletsov, Valeriy M.; Timofeev, Vladimir F.; Tyan, Oleg A.; Vetluzhskikh, Valeriy G.; Aihua, Xi; Yakovlev, Yakov V.; Hongquan, Yan; Zhizhin, Vladimir I.; Zinchuk, Nikolay N.; Zorina, Lydia M.

2003-01-01

Introduction This report contains a digtial database on lode deposits and placer districts of Northeast Asia. This region includes Eastern Siberia, Russian Far East, Mongolia, Northeast China, South Korea, and Japan. In folders on this site are a detailed database, a bibliography of cited references, descriptions of mineral deposit models, and a mineral deposit location map. Data are provided for 1,674 significant lode deposits and 91 significant placer districts of the region.

A Regional Analysis of Non-Methane Hydrocarbons And Meteorology of The Rural Southeast United States

DTIC Science & Technology

1996-01-01

Zt is an ARIMA time series. This is a typical regression model , except that it allows for autocorrelation in the error term Z. In this work, an ARMA...data=folder; var residual; run; II Statistical output of 1992 regression model on 1993 ozone data ARIMA Procedure Maximum Likelihood Estimation Approx...at each of the sites, and to show the effect of synoptic meteorology on high ozone by examining NOAA daily weather maps and climatic data

Investigation into the High Voltage Shutdown of the Oxygen Generator System in the International Space Station

NASA Technical Reports Server (NTRS)

Carpenter, Joyce E.; Gentry, Gregory J.; Diderich, Greg S.; Roy, Robert J.; Golden, John L.; VanKeuren, Steve; Steele, John W.; Rector, Tony J.; Varsik, Jerome D.; Montefusco, Daniel J.;

Development of Lead Compounds as Fusion Inhibitors for Dengue Virus

DTIC Science & Technology

2009-08-01

19a. NAME OF RESPONSIBLE PERSON USAMRMC a. REPORT U b . ABSTRACT U c. THIS PAGE U UU 61 19b. TELEPHONE NUMBER (include area code...and III (blue). B ) Structural alignment of E2 protein monomer in the absence and presence of βOG (pdbIDs 1OAN and 1OKE respectively), with the kl-β...hairpin loop colored as follows: prefusion state (yellow), intermediate βOG-E2 complex (blue), secondary structure colored by B -factor from blue

A comparison of two antigen-detection ELISA for detecting infection of Dirofilaria immitis in dogs.

PubMed

Euclid, J M; Copeman, D B

1997-09-01

A survey on 87 dogs necropsied in the Townsville region revealed 34 (39%) were infected with Dirofilaria immitis. Infected dogs had an average of 6.1 adult worms in the heart and associated blood vessels. The VetRED assay detected 23 of the 34 infected dogs (sensitivity 65%) and the Og4C3 ELISA detected 27 (sensitivity 80%). Sensitivity of the VetRED and Og4C3 ELISA increased to 88 and 94% respectively in dogs with three or more worms. Both tests detected correctly all uninfected dogs. Despite the higher accuracy of the Og4C3 ELISA, compared to the VetRED assay, it is unlikely to be used widely as a field test for heartworm unless it can be modified from its present plate ELISA format which takes 4 hours, into one which is more rapid and convenient. However, as a reference ELISA, it may well be worthwhile in situations which require considerable accuracy for detecting D. immitis infection.

SANS with contrast variation study of the bacteriorhodopsin-octyl glucoside complex

NASA Astrophysics Data System (ADS)

Mo, Yiming; Heller, William T.

2010-11-01

Membrane proteins (MPs), which play vital roles in trans-membrane trafficking and signalling between cells and their external environment, comprise a major fraction of the expressed proteomes of many organisms. MP production for biophysical characterization requires detergents for extracting MPs from their native membrane and to solubilize the MP in solution for purification and study. In a proper detergent solution, the detergent-associated MPs retain their native fold and oligomerization state, key requirements for biophysical characterization and crystallization. SANS with contrast variation was performed to characterize BR in complex with OG to better understand the MP-detergent complex. Contrast variation makes it possible to not only probe the conformation of the entire structure but also investigate the conformation of the polypeptide chain within the BR-OG complex. The BR-OG SANS contrast variation series is not consistent with a compact structure, such as a trimeric BR complex surrounded by a belt of detergent. The data strongly suggest that the protein is partially unfolded through its association with the detergent micelles.

Enterococcus faecalis Ebp pili are important for cell-cell aggregation and intraspecies gene transfer

PubMed Central

Leanti La Rosa, Sabina; Camila Montealegre, Maria; Singh, Kavindra V.

2016-01-01

Enterococcus faecalis is an opportunistic pathogen that ranks among the leading causes of biofilm-associated infections. We previously demonstrated that the endocarditis- and biofilm-associated pili (Ebp) of E. faecalis play a major role in biofilm formation, adherence to abiotic surfaces and experimental infections. In this study, derivatives of E. faecalis strain OG1 were engineered to further characterize functions of Ebp pili. Loss of pili resulted in a 36-fold decrease in the number of closely associated cells when OG1RFΔebpABC was mixed with OG1SSpΔebpABC, compared with mixing the Ebp+ parental strains. In addition, using the Ebp+ parental strains as donor and recipient, we found a statistically significant increase (280–360 %, P < 0.05) in the frequency of plasmid transfer versus using Ebp−  mutants in the conjugation experiments. These results demonstrate a previously unrecognized role of Ebp pili, namely, as important contributors to microscale cell aggregation and horizontal spread of genetic material. PMID:26967674

Oligomerization state of water channels and glycerol facilitators. Involvement of loop E.

PubMed

Lagrée, V; Froger, A; Deschamps, S; Pellerin, I; Delamarche, C; Bonnec, G; Gouranton, J; Thomas, D; Hubert, J F

1998-12-18

The major intrinsic protein (MIP) family includes water channels aquaporins (AQPs) and facilitators for small solutes such as glycerol (GlpFs). Velocity sedimentation on sucrose gradients demonstrates that heterologous AQPcic expressed in yeast or Xenopus oocytes behaves as an homotetramer when extracted by n-octyl beta-D-glucopyranoside (OG) and as a monomer when extracted by SDS. We performed an analysis of GlpF solubilized from membranes of Escherichia coli or of mRNA-injected Xenopus oocytes. The GlpF protein extracted either by SDS or by nondenaturing detergents, OG and Triton X-100, exhibits sedimentation coefficients only compatible with a monomeric form of the protein in micelles. We then substituted in loop E of AQPcic two amino acids predicted to play a role in the functional/structural properties of the MIPs. In two expression systems, yeast and oocytes, the mutant AQPcic-S205D is monomeric in OG and in SDS. The A209K mutation does not modify the tetrameric form of the heterologous protein in OG. This study shows that the serine residue at position 205 is essential for AQPcic tetramerization. Because the serine in this position is highly conserved among aquaporins and systematically replaced by an acid aspartic in GlpFs, we postulate that glycerol facilitators are monomers whereas aquaporins are organized in tetramers. Our data suggest that the role of loop E in MIP properties partly occurs through its ability to allow oligomerization of the proteins.

Effect of oral glucose administration on rebound growth hormone release in normal and obese women: the role of adiposity, insulin sensitivity and ghrelin.

PubMed

Pena-Bello, Lara; Pertega-Diaz, Sonia; Outeiriño-Blanco, Elena; Garcia-Buela, Jesus; Tovar, Sulay; Sangiao-Alvarellos, Susana; Dieguez, Carlos; Cordido, Fernando

2015-01-01

Metabolic substrates and nutritional status play a major role in growth hormone (GH) secretion. Uncovering the mechanisms involved in GH secretion following oral glucose (OG) administration in normal and obese patients is a pending issue. The aim of this study was to investigate GH after OG in relation with adiposity, insulin secretion and action, and ghrelin secretion in obese and healthy women, to further elucidate the mechanism of GH secretion after OG and the altered GH secretion in obesity. We included 64 healthy and obese women. After an overnight fast, 75 g of OG were administered; GH, glucose, insulin and ghrelin were obtained during 300 minutes. Insulin secretion and action indices and the area under the curve (AUC) were calculated for GH, glucose, insulin and ghrelin. Univariate and multivariate linear regression analyses were employed. The AUC of GH (μg/L•min) was lower in obese (249.8±41.8) than in healthy women (490.4±74.6), P=0.001. The AUC of total ghrelin (pg/mL•min) was lower in obese (240995.5±11094.2) than in healthy women (340797.5±37757.5), P=0.042. There were significant correlations between GH secretion and the different adiposity, insulin secretion and action, and ghrelin secretion indices. After multivariate analysis only ghrelin AUC remained a significant predictor for fasting and peak GH.

Effect of Oral Glucose Administration on Rebound Growth Hormone Release in Normal and Obese Women: The Role of Adiposity, Insulin Sensitivity and Ghrelin

PubMed Central

Pena-Bello, Lara; Pertega-Diaz, Sonia; Outeiriño-Blanco, Elena; Garcia-Buela, Jesus; Tovar, Sulay; Sangiao-Alvarellos, Susana; Dieguez, Carlos; Cordido, Fernando

2015-01-01

Context Metabolic substrates and nutritional status play a major role in growth hormone (GH) secretion. Uncovering the mechanisms involved in GH secretion following oral glucose (OG) administration in normal and obese patients is a pending issue. Objective The aim of this study was to investigate GH after OG in relation with adiposity, insulin secretion and action, and ghrelin secretion in obese and healthy women, to further elucidate the mechanism of GH secretion after OG and the altered GH secretion in obesity. Participants and Methods We included 64 healthy and obese women. After an overnight fast, 75 g of OG were administered; GH, glucose, insulin and ghrelin were obtained during 300 minutes. Insulin secretion and action indices and the area under the curve (AUC) were calculated for GH, glucose, insulin and ghrelin. Univariate and multivariate linear regression analyses were employed. Results The AUC of GH (μg/L•min) was lower in obese (249.8±41.8) than in healthy women (490.4±74.6), P=0.001. The AUC of total ghrelin (pg/mL•min) was lower in obese (240995.5±11094.2) than in healthy women (340797.5±37757.5), P=0.042. There were significant correlations between GH secretion and the different adiposity, insulin secretion and action, and ghrelin secretion indices. After multivariate analysis only ghrelin AUC remained a significant predictor for fasting and peak GH. PMID:25782001

Computational analysis of pediatric ventricular assist device implantation to decrease cerebral particulate embolization.

PubMed

Nguyen, ThuyTien; Argueta-Morales, I Ricardo; Guimond, Stephen; Clark, William; Ceballos, Andres; Osorio, Ruben; Divo, Eduardo A; De Campli, William M; Kassab, Alain J

2016-01-01

Stroke is the most devastating complication after ventricular assist device (VAD) implantation with a 19% incidence and 65% mortality in the pediatric population. Current pediatric VAD technology and anticoagulation strategies alone are suboptimal. VAD implantation assisted by computational methods (CFD) may contribute reducing the risk of cerebral embolization. Representative three-dimensional aortic arch models of an infant and a child were generated. An 8 mm VAD outflow-graft (VAD-OG) anastomosed to the aorta was rendered and CFD was applied to study blood flow patterns. Particle tracks, originating in the VAD, were computed with a Lagrangian phase model and the percentage of particles entering the cerebral vessels was calculated. Eight implantation configurations (infant = 5 and child = 3) and 5 particle sizes (0.5, 1, 2, 3, and 4 mm) were considered. For the infant model, percentage of particles entering the cerebral vessels ranged from 15% for a VAD-OG anastomosed at 90° to the aorta, to 31% for 30° VAD-OG anastomosis (overall percentages: X(2) = 10,852, p < 0.0001). For the child model, cerebral embolization ranged from 9% for the 30° VAD-OG anastomosis to 15% for the 60° anastomosis (overall percentages: χ(2) = 10,323, p < 0.0001). Using detailed CFD calculations, we demonstrate that the risk of stroke depends significantly on the VAD implantation geometry. In turn, the risk probably depends on patient-specific anatomy. CFD can be used to optimize VAD implantation geometry to minimize stroke risk.