Sample records for form factor sff

  1. Prism-type holographic optical element design and verification for the blue-light small-form-factor optical pickup head.

    PubMed

    Shih, Hsi-Fu; Chiu, Yi; Cheng, Stone; Lee, Yuan-Chin; Lu, Chun-Shin; Chen, Yung-Chih; Chiou, Jin-Chern

    2012-08-20

    This paper presents the prism-type holographic optical element (PT-HOE) design for a small-form-factor (SFF) optical pickup head (OPH). The surface of the PT-HOE was simulated by three steps of optimization and generated by binary optics. Its grating pattern was fabricated on the inclined plane of a microprism by using the standard photolithography and specific dicing procedures. The optical characteristics of the device were verified. Based on the virtual image method, the SFF-OPH with the device was assembled and realized.

  2. Solid Free-form Fabrication Technology and Its Application to Bone Tissue Engineering

    PubMed Central

    Lee, Jin Woo; Kim, Jong Young; Cho, Dong-Woo

    2010-01-01

    The development of scaffolds for use in cell-based therapies to repair damaged bone tissue has become a critical component in the field of bone tissue engineering. However, design of scaffolds using conventional fabrication techniques has limited further advancement, due to a lack of the required precision and reproducibility. To overcome these constraints, bone tissue engineers have focused on solid free-form fabrication (SFF) techniques to generate porous, fully interconnected scaffolds for bone tissue engineering applications. This paper reviews the potential application of SFF fabrication technologies for bone tissue engineering with respect to scaffold fabrication. In the near future, bone scaffolds made using SFF apparatus should become effective therapies for bone defects. PMID:24855546

  3. Genetic changes induced by space flight factors in barley seeds on Soyuz-5 and Soyuz-9 craft

    NASA Technical Reports Server (NTRS)

    Nuzhdin, N. I.; Dozortseva, R. L.

    1980-01-01

    Air-dry seeds of the barley Zimujuschij moscowskyi of the 1969 harvest were taken into space onboard the spaceships Soyuz-5 and Soyuz-9. A cytological study of the mitoses in meristemic cells in rootlet terminals revealed that space flight factors (SFF) in nonirradiated seeds induced about 3% of aberrant cells. After irradiation the effect of SFF increased over two-fold. Although the radio protectors ensured the seeds against from the SFF-induced damage either in irradiated or nonirradiated seed cells which is inconsistent with the previously obtained data.

  4. Risk of defeats in the central nervous system during deep space missions.

    PubMed

    Kokhan, Viktor S; Matveeva, Marina I; Mukhametov, Azat; Shtemberg, Andrey S

    2016-12-01

    Space flight factors (SFF) significantly affect the operating activity of astronauts during deep space missions. Gravitational overloads, hypo-magnetic field and ionizing radiation are the main SFF that perturb the normal activity of the central nervous system (CNS). Acute and chronic CNS risks include alterations in cognitive abilities, reduction of motor functions and behavioural changes. Multiple experimental works have been devoted to the SFF effects on integrative functional activity of the brain; however, the model parameters utilized have not always been ideal and consistent. Even less is known regarding the combined effects of these SFF in a real interplanetary mission, for example to Mars. Our review aims to systemize and analyse the last advancements in astrobiology, with a focus on the combined effects of SFF; as well as to discuss on unification of the parameters for ground-based models of deep space missions. Copyright © 2016 Elsevier Ltd. All rights reserved.

  5. Structural and material approaches to bone tissue engineering in powder-based three-dimensional printing.

    PubMed

    Butscher, A; Bohner, M; Hofmann, S; Gauckler, L; Müller, R

    2011-03-01

    This article reviews the current state of knowledge concerning the use of powder-based three-dimensional printing (3DP) for the synthesis of bone tissue engineering scaffolds. 3DP is a solid free-form fabrication (SFF) technique building up complex open porous 3D structures layer by layer (a bottom-up approach). In contrast to traditional fabrication techniques generally subtracting material step by step (a top-down approach), SFF approaches allow nearly unlimited designs and a large variety of materials to be used for scaffold engineering. Today's state of the art materials, as well as the mechanical and structural requirements for bone scaffolds, are summarized and discussed in relation to the technical feasibility of their use in 3DP. Advances in the field of 3DP are presented and compared with other SFF methods. Existing strategies on material and design control of scaffolds are reviewed. Finally, the possibilities and limiting factors are addressed and potential strategies to improve 3DP for scaffold engineering are proposed. Copyright © 2010 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.

  6. Biological properties of solid free form designed ceramic scaffolds with BMP-2: in vitro and in vivo evaluation.

    PubMed

    Abarrategi, Ander; Moreno-Vicente, Carolina; Martínez-Vázquez, Francisco Javier; Civantos, Ana; Ramos, Viviana; Sanz-Casado, José Vicente; Martínez-Corriá, Ramón; Perera, Fidel Hugo; Mulero, Francisca; Miranda, Pedro; López-Lacomba, José Luís

    2012-01-01

    Porous ceramic scaffolds are widely studied in the tissue engineering field due to their potential in medical applications as bone substitutes or as bone-filling materials. Solid free form (SFF) fabrication methods allow fabrication of ceramic scaffolds with fully controlled pore architecture, which opens new perspectives in bone tissue regeneration materials. However, little experimentation has been performed about real biological properties and possible applications of SFF designed 3D ceramic scaffolds. Thus, here the biological properties of a specific SFF scaffold are evaluated first, both in vitro and in vivo, and later scaffolds are also implanted in pig maxillary defect, which is a model for a possible application in maxillofacial surgery. In vitro results show good biocompatibility of the scaffolds, promoting cell ingrowth. In vivo results indicate that material on its own conducts surrounding tissue and allow cell ingrowth, thanks to the designed pore size. Additional osteoinductive properties were obtained with BMP-2, which was loaded on scaffolds, and optimal bone formation was observed in pig implantation model. Collectively, data show that SFF scaffolds have real application possibilities for bone tissue engineering purposes, with the main advantage of being fully customizable 3D structures.

  7. Biological Properties of Solid Free Form Designed Ceramic Scaffolds with BMP-2: In Vitro and In Vivo Evaluation

    PubMed Central

    Abarrategi, Ander; Moreno-Vicente, Carolina; Martínez-Vázquez, Francisco Javier; Civantos, Ana; Ramos, Viviana; Sanz-Casado, José Vicente; Martínez-Corriá, Ramón; Perera, Fidel Hugo; Mulero, Francisca; Miranda, Pedro; López-Lacomba, José Luís

    2012-01-01

    Porous ceramic scaffolds are widely studied in the tissue engineering field due to their potential in medical applications as bone substitutes or as bone-filling materials. Solid free form (SFF) fabrication methods allow fabrication of ceramic scaffolds with fully controlled pore architecture, which opens new perspectives in bone tissue regeneration materials. However, little experimentation has been performed about real biological properties and possible applications of SFF designed 3D ceramic scaffolds. Thus, here the biological properties of a specific SFF scaffold are evaluated first, both in vitro and in vivo, and later scaffolds are also implanted in pig maxillary defect, which is a model for a possible application in maxillofacial surgery. In vitro results show good biocompatibility of the scaffolds, promoting cell ingrowth. In vivo results indicate that material on its own conducts surrounding tissue and allow cell ingrowth, thanks to the designed pore size. Additional osteoinductive properties were obtained with BMP-2, which was loaded on scaffolds, and optimal bone formation was observed in pig implantation model. Collectively, data show that SFF scaffolds have real application possibilities for bone tissue engineering purposes, with the main advantage of being fully customizable 3D structures. PMID:22470527

  8. Combined effects of antiorthostatic suspension and ionizing radiation on the behaviour and neurotransmitters changes in different brain structures of rats.

    PubMed

    Kokhan, V S; Matveeva, M I; Bazyan, A S; Kudrin, V S; Mukhametov, A; Shtemberg, A S

    2017-03-01

    Space flight factors (SFF) significantly affect the operating activity of astronauts during deep space missions. In contrast to an orbital flight, leaving the Earth's magnetic field is fraught with the dangers of exposure to ionizing radiation and more specifically, the high-energy nuclei component of galactic cosmic rays. Microgravity, just another critical non-radiation factor, significantly affects the normal functioning of the CNS. Some morphological structures of the brain, such as the prefrontal cortex and the hippocampus, that are rich in monoaminergic and acetylcholinergic neurones, are the most sensitive to the effects of ionizing radiation and non-radiation spaceflight factors (SFF). In this work we have studied the combined effects of microgravity (in antiorthostatic suspension model, AS) and irradiation (γ-ray and protons in spread-out Bragg peak) on the behaviour, cognitive abilities, and metabolism of monoamines and acetylcholine in the key structures of the rat's brain. Irradiation (as independently as combined with AS) resulted in the decrease of thigmotaxis in rats. Learning problems, caused by the malfunctioning of the working memory but not the spatial memory, were observed in response to AS as well as to the SFF in combination. Analysis of monoamines metabolism showed that the serotoninergic system was the most affected by the SFF. Concentration of acetylcholine in the hippocampus significantly increased in the groups of irradiated rats, and in the groups which were exposed to the SFF in combination, compared to the rats exposed only to AS. Copyright © 2016 Elsevier B.V. All rights reserved.

  9. Investigation of the structure of unilamellar dimyristoylphosphatidylcholine vesicles in aqueous sucrose solutions by small-angle neutron and X-ray scattering

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kiselev, M. A., E-mail: elena@jinr.ru; Zemlyanaya, E. V.; Zhabitskaya, E. I.

    2015-01-15

    The structure of a polydispersed population of unilamellar dimyristoylphosphatidylcholine (DMPC) vesicles in sucrose solutions has been investigated by small-angle neutron scattering (SANS) and small-angle X-ray scattering (SAXS). Calculations within the model of separated form factors (SFF) show that the structure of the vesicle system depends strongly on the sucrose concentration.

  10. Propulsion Design With Freeform Fabrication (PDFF)

    NASA Technical Reports Server (NTRS)

    Barnes, Daudi; McKinnon, James; Priem, Richard

    2010-01-01

    The nation is challenged to decrease the cost and schedule to develop new space transportation propulsion systems for commercial, scientific, and military purposes. Better design criteria and manufacturing techniques for small thrusters are needed to meet current applications in missile defense, space, and satellite propulsion. The requirements of these systems present size, performance, and environmental demands on these thrusters that have posed significant challenges to the current designers and manufacturers. Designers are limited by manufacturing processes, which are complex, costly, and time consuming, and ultimately limited in their capabilities. The PDFF innovation vastly extends the design opportunities of rocket engine components and systems by making use of the unique manufacturing freedom of solid freeform rapid prototype manufacturing technology combined with the benefits of ceramic materials. The unique features of PDFF are developing and implementing a design methodology that uses solid freeform fabrication (SFF) techniques to make propulsion components with significantly improved performance, thermal management, power density, and stability, while reducing development and production costs. PDFF extends the design process envelope beyond conventional constraints by leveraging the key feature of the SFF technique with the capability to form objects with nearly any geometric complexity without the need for elaborate machine setup. The marriage of SFF technology to propulsion components allows an evolution of design practice to harmonize material properties with functional design efficiency. Reduced density of materials when coupled with the capability to honeycomb structure used in the injector will have significant impact on overall mass reduction. Typical thrusters in use for attitude control have 60 90 percent of its mass in the valve and injector, which is typically made from titanium. The combination of material and structure envisioned for use in an SFF thruster design could reduce thruster weight by a factor of two or more. The thrust-to-weight ratios for such designs can achieve 1,000:1 or more, depending on chamber pressure. The potential exists for continued development in materials, size, speed, accuracy of SFF techniques, which can lead to speculative developments of PDFF processes such as fabrication of custom human interface devices like masks, chairs, and clothing, and advanced biomedical application to human organ reconstruction. Other potential applications are: higher fidelity lower cost test fixtures for probes and inspection, disposable thrusters, and ISRU (in situ resource utilization) for component production in space or on Lunar and Martian missions, and application for embedding MEMS (microelectromechanical systems) during construction process of form changing aerostructure/dynamic structures.

  11. Solid freeform fabrication using chemically reactive suspensions

    DOEpatents

    Morisette, Sherry L.; Cesarano, III, Joseph; Lewis, Jennifer A.; Dimos, Duane B.

    2002-01-01

    The effects of processing parameters and suspension chemorheology on the deposition behavior of SFF components derived from polymeric-based gelcasting suspensions combines the advantages associated with SFF fabrication, including the ability to spatially tailor composition and structure as well as reduced tooling costs, with the improved handling strength afforded by the use of gel based formulations. As-cast free-formed Al.sub.2 O.sub.3 components exhibited uniform particle packing and had minimal macro-defects (e.g., slumping or stair casing) and no discernable micro-defects (e.g., bubbles or cracking).

  12. Sex Differences in Pitch Range and Speech Fundamental Frequency After Arytenoid Adduction and Thyroplasty.

    PubMed

    Konomi, Ujimoto; Watanabe, Yusuke; Komazawa, Daigo

    2016-05-01

    The purpose of this study was to clarify the sex differences in pitch range (PR) and speech fundamental frequency (SFF) after arytenoid adduction (AA) combined with type 1 thyroplasty (TP1) in patients with unilateral vocal fold paralysis (UVFP) and to assess the cause of these differences. This is a retrospective review of clinical records. The records of 50 patients with UVFP for whom PR, SFF, and maximum phonation time (MPT) had been evaluated before and 1 year after AA combined with TP1 were analyzed. Patients consisted of 36 men and 14 women. In particular, in the 37 patients (24 men and 13 women) who had ≥2 semitones (STs) in preoperative PR (pre-PR), the differences and correlations between the pre-PR and the postoperative PR (post-PR), SFF, and MPT were compared between the sexes. We also discussed cases of post-PR deterioration and abnormal SFF. The characteristics of PR in men are narrow pre-PR (14.7 ± 11.5 STs) and significant extension of post-PR (22.6 ± 6.3 STs). MPT extended from 4.6 ± 2.5 seconds to 14.8 ± 7.2 seconds. In contrast, women had a wide pre-PR (18.1 ± 7.2 STs) and showed no significant post-PR extension (21.7 ± 7.8 STs). MPT extended from 5.1 ± 1.9 seconds to 16.8 ± 7.2 seconds. Although there were no significant changes in average SFF, as well as the highest and lowest pitch after the operation, the variance of the pre-SFF tended to converge into the physiological range in the post-SFF (P = 0.08). Compared with the SFF data of normal adult controls, post-SFF in the normal range was 46.0% (23/50). In patients who showed a >20% improvement in PR, normal post-SFF appeared in 68.8% of the patients (11/16). Particularly in those women, 83.3% (5/6) showed a normal post-SFF. Men showed greater difficulty in recovery of normal PR, SFF, and MPT; however, there were fewer patients (4.2%; 1/24) with a PR deterioration of >20%. Regarding women, although some patients showed a parallel recovery in PR and SFF to the normal range, there was a high rate of patients showing PR deterioration (30.8%; 4/13). AA combined with TP1 resulted in the recovery of not only MPT but also PR and SFF. In addition, sex differences in operative effects were suggested. In men, although MPT is difficult to be fully recovered, PR deterioration was mild. In women, although MPT was more easily extended, PR deterioration occurred more readily because of operative effects such as hypermedialization of their smaller larynx. The post-PR variation appeared to be associated with SFF. Our results indicate the necessity to assess patients' PR and SFF even if their MPTs recover, particularly in patients with postoperative voice insufficiency. Copyright © 2016 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  13. Acute effects of a herb extract formulation and inulin fibre on appetite, energy intake and food choice.

    PubMed

    Harrold, J A; Hughes, G M; O'Shiel, K; Quinn, E; Boyland, E J; Williams, N J; Halford, J C G

    2013-03-01

    The impact of two commercially available products, a patented herb extract Yerbe Maté, Guarana and Damiana (YGD) formulation and an inulin-based soluble fermentable fibre (SFF), alone or in combination, on appetite and food intake were studied for the first time in a double blind, placebo-controlled, cross-over design. 58 normal to slightly overweight women consumed a fixed-load breakfast followed 4h later by an ad libitum lunch. They were administered YGD (3 tablets) and SFF (5g in 100ml water), YGD and water (100ml), SFF and placebo (3 tablets) or water and placebo 15min before meals. Appetite was assessed using visual analogue scales, and energy intake was measured at lunch. Significant reductions in food intake and energy intake were observed when YGD was present (59.5g, 16.3%; 112.4kcal, 17.3%) and when SFF was present (31.9g, 9.1%; 80kcal, 11.7%) compared with conditions were products were absent. The lowest intake (gram and kcal) was in the YGD+SFF condition. Significant reductions in AUC hunger and AUC desire to eat were also observed after YGD+SFF combination. The data demonstrate that YGD produces a robust short-term effect on caloric intake, an effect augmented by SFF. Caloric compensation for SFF indicates independent effects on appetite regulation. Copyright © 2012 Elsevier Ltd. All rights reserved.

  14. Changes in speaking fundamental frequency characteristics with aging.

    PubMed

    Nishio, Masaki; Niimi, Seiji

    2008-01-01

    Changes in speaking fundamental frequency (SFF) associated with aging were studied in a total of 374 healthy normal speakers (187 males and 187 females) from adolescent to older age groups. Participants were asked to read a sample passage aloud, and acoustic analysis was performed. The main results were as follows: (1) Males exhibited no significant trend for SFF changes in aging. However, a slight increase was observed in participants aged 70 years or older. (2) Females in their 30s and 40s showed obviously lower frequencies than those in their 20s. Across all age groups, including the 80s, SFF tended to decrease markedly in association with aging. (3) The degree of SFF change in association with aging was much larger in females than in males. In addition, reference intervals (mean +/- 1.96 SD) obtained for males and females in each age group are considered useful for clinical detection of abnormalities of SFF, as well as for detection of laryngeal diseases causing SFF abnormality. 2008 S. Karger AG, Basel.

  15. Does excessive flatfoot deformity affect function? A comparison between symptomatic and asymptomatic flatfeet using the Oxford Foot Model.

    PubMed

    Hösl, Matthias; Böhm, Harald; Multerer, Christel; Döderlein, Leonhard

    2014-01-01

    Treatment of asymptomatic flexible flatfeet is a subject of great controversy. The purpose of this study was to examine foot function during walking in symptomatic (SFF) and asymptomatic (ASFF) flexible flatfeet. Thirty-five paediatric and juvenile patients with idiopathic flexible flatfeet were recruited from an orthopaedic outpatient department (14 SFF and 21 ASFF). Eleven age-matched participants with typically developing feet served as controls (TDF). To study foot function, 3D multi-segment foot kinematics and ankle joint kinetics were captured during barefoot gait analysis. Overall, alterations in foot kinematics in flatfeet were pronounced but differences between SFF and ASFF were not observed. Largest discriminatory effects between flatfeet and TDF were noticed in reduced hindfoot dorsiflexion as well as in increased forefoot supination and abduction. Upon clinical examination, restrictions in passive dorsiflexion in ASFF and SFF were significant. During gait, the hindfoot in flatfeet (both ASFF and SFF) was more everted, but less flexible. In sagittal plane, limited hindfoot dorsiflexion of ASFF and SFF was compensated for by increased forefoot mobility and a hypermobile hallux. Concerning ankle kinetics, SFF lacked positive joint energy for propulsion while ASFF needed to absorb more negative ankle joint energy during loading response. This may risk fatigue and overuse syndrome of anterior shank muscles in ASFF. Hence, despite a lack of symptoms flatfoot deformity in ASFF affected function. Yet, contrary to what was expected, SFF did not show greater deviations in 3D foot kinematics than ASFF. Symptoms may rather depend on tissue wear and subjective pain thresholds. Copyright © 2013. Published by Elsevier B.V.

  16. In situ bioinspired synthesis of silver chloride nanocrystals on silk fibroin fibers

    NASA Astrophysics Data System (ADS)

    Su, Huilan; Han, Jie; Dong, Qun; Xu, Jia; Chen, Ying; Gu, Yu; Song, Weiqiang; Zhang, Di

    2011-02-01

    Silver chloride (AgCl) nanocrystals were formed and grown on silk fibroin fibers (SFFs) by a room-temperature process. Practically, the degummed SFFs were immersed into silver nitrate solution and sodium chloride solution in turn. The amino acids on the SFF surface were negatively charged in alkaline impregnant, providing locations to immobilize silver ions and form silver chloride seeds. AgCl nanocrystals can further grow into cubic AgCl nanocrystals with an edge of about 100 nm. The morphologies of the AgCl nanocrystals were mostly influenced by the concentration of sodium chloride solution and the special configurations of the SFFs. The target AgCl/SFF nanocomposites constructed by AgCl nanocrystals and substrate SFFs could be used as photocatalysts in water splitting and antibacterial agents. This work provides an important example in the introduction of natural biofibers to the synthesis of functional hybrid nanocomposites by a green and mild technique.

  17. Fundamental voice frequence during normal and abnormal growth, and after androgen treatment.

    PubMed Central

    Vuorenkoski, V; Lenko, H L; Tjernlund, P; Vuorenkoski, L; Perheentupa, J

    1978-01-01

    A simple treatment was shown to be suitable for clinical measurement of fundamental voice frequency. Basal frequency (SFF) and lowest frequency (LF) were determined in 374 normal subjects aged 6 years to adulthood. SFF fell between ages 8 and 10 years in boys (from 259 to 247 Hz), but not in girls (253 Hz). LF fell between ages 6 and 10 years in boys (from 234 to 203 Hz) and girls (from 230 to 218 Hz), and a sex difference appeared. In puberty, parallel to pubic hair (PH) development, a gradual fall of SFF and LF occurred in both boys (to 100 and 90 Hz, respectively) and girls (to 213 and 180 Hz). As a group, young hypopituitary children and girls with Turner's syndrome had a high SFF, and prepubertal boys with delayed maturation a low SFF. In some children with prenatal growth failure, SFF was abnormally high. The girls with Turner's syndrome exhibited a high, though individually variable, sensitivity of voice to androgen; their voices became lower before the appearance of any other masculinising effects. The instrument is useful for characterisation of growth failure syndromes and stages of puberty. It is particularly recommended for monitoring an undesirable effect on the voice during androgen treatment. Images Fig. 1 p202-b PMID:646429

  18. Comparative studies of pharmacokinetics and anticoagulatory effect in rats after oral administration of Frankincense and its processed products.

    PubMed

    Pan, Ying-Ni; Liang, Xiao-Xu; Niu, Li-Ying; Wang, Yan-Nian; Tong, Xin; Hua, Hui-Ming; Zheng, Jiang; Meng, Dong-Ya; Liu, Xiao-Qiu

    2015-08-22

    Frankincense (FRA), Ruxiang, is the resin of Boswellia carterii Birdw and Boswellia bhaw-dajiana Birdw which has been used for centuries as formulas to improve the circulation and to relieve pain against carbuncles. Stir-fried Frankincense (SFF) and vinegar processed Frankincense (VPF) are two major processed Frankincense, and the processing procedures reportedly enhance the curative efficacy or reduce the side effects of FRA. This paper describes the comparisons in plasma pharmacokinetic behaviors of 11-keto-β-boswellic acid (KBA) and 3-acetyl-11-keto-β-boswellic acid (AKBA) in FRA and its processed products, and their effects on coagulation factors and blood clotting tetrachoric, using an acute cold blood-stasis animal model after oral administration of FRA, SFF, and VPF. For pharmacokinetic study, Sprague-Dawley (SD) rats were randomly divided into three groups, including group FRA, group SFF and group VPF. And the plasma samples were analyzed by HPLC. For study of anticoagulatory effect, SD rats were randomly divided into six groups, including control, acute cold blood-stasis model, Fu-fang-dan-shen tablet- (0.75g/kg), FRA-, SFF-, and VPF-treated (2.7g/kg) groups, respectively. The serum contents of thrombin-antithrombin complex (TAT), D-dimer (D-D), and prostacyclin (PGI2) of each group were measured by ELISA. The values of prothrombin time (PT), thrombin time (TT), activated partial thromboplastin time (APTT) and fibrinogen (FIB) were also assessed by hematology analyzer. Significantly increased levels of Cmax, AUC, T1/2, and MRT were found in rats treated with the processed products. In addition, decreased levels of D-D and TAT and increased contents of PGI2 were observed in rats given FRA and its processed products, compared with that of the model group. Moreover, VPF improved anticoagulation more than SFF in the animals. The observed improvement of anticoagulation by processed FRA may result from the increased absorption and bioavailability of triterpenoids. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  19. Guiding characteristics of sunflower-type fiber

    NASA Astrophysics Data System (ADS)

    Liu, Exian; Yan, Bei; Tan, Wei; Xie, Jianlan; Ge, Rui; Liu, Jianjun

    2018-03-01

    In this paper, the guiding characteristics of sunflower-type fiber (SFF) with 6-fold rotational symmetry are investigated theoretically using finite element method (FEM). The behavior of single-mode propagation in SFF is verified. Numerical results reveal that, the cutoff ratio for endlessly single-mode propagation in SFF is 0.575 which is larger than that of photonic crystal fiber (PCF) and photonic quasi-crystal fiber (PQF). Moreover, SFF can present ultra-flattened near-zero chromatic dispersion, 0.249 ± 1.146 ps/nm/km, in a broadband of wavelength covering 1.20-1.84 μm over all the telecommunication wavelengths. In term of chromatic dispersion and confinement loss in the wavelength range from 1.00 to 2.00 μm, a comparison between SFF, PCF and PQF with same structure parameters is carried out. Importantly, the rotational symmetry, as a new manageable structure parameter beyond common air hole diameter and lattice constant, can be employed to manipulate the chromatic dispersion, confinement loss, effective mode area and non-linear coefficient and it dependences on these guiding characteristics are discussed in detail.

  20. Average speaking fundamental frequency in soprano singers with and without symptoms of vocal attrition.

    PubMed

    Drew, R; Sapir, S

    1995-06-01

    Nineteen trained soprano singers aged 18-30 years vocalized tasks designed to assess average speaking fundamental frequency (SFF) during spontaneous speaking and reading. Vocal range and perceptual characteristics while singing with low intensity and high frequency were also assessed, and subjects completed a survey of vocal habits/symptoms. Recorded signals were digitized prior to being analyzed for SFF using the Kay Computerized Speech Lab program. Subjects were assigned to a normal voice or impaired voice group based on ratings of perceptual tasks and survey results. Data analysis showed group differences in mean SFF, no differences in vocal range, higher mean SFF values for reading than speaking, and 58% ability to perceive speaking in low pitch. The role of speaking in too low pitch as causal for vocal symptoms and need for voice classification differentiation in vocal performance studies are discussed.

  1. Prenatal choline availability modulates hippocampal neurogenesis and neurogenic responses to enriching experiences in adult female rats

    PubMed Central

    Glenn, Melissa J.; Gibson, Erin M.; Kirby, Elizabeth D.; Mellott, Tiffany J.; Blusztajn, Jan K.; Williams, Christina L.

    2008-01-01

    Increased dietary intake of choline early in life improves performance of adult rats on memory tasks and prevents their age-related memory decline. Because neurogenesis in the adult hippocampus also declines with age, we investigated whether prenatal choline availability affects hippocampal neurogenesis in adult Sprague–Dawley rats and modifies their neurogenic response to environmental stimulation. On embryonic days (ED) 12−17, pregnant rats ate a choline-supplemented (SUP-5 g/kg), choline sufficient (SFF-1.1 g/kg), or choline-free (DEF) semisynthetic diet. Adult offspring either remained in standard housing or were given 21 daily visits to explore a maze. On the last ten exploration days, all rats received daily injections of 5-bromo-2-deoxyuridine (BrdU, 100 mg/kg). The number of BrdU+ cells was significantly greater in the dentate gyrus in SUP rats compared to SFF or DEF rats. While maze experience increased the number of BrdU+ cells in SFF rats to the level seen in the SUP rats, this enriching experience did not alter cell proliferation in DEF rats. Similar patterns of cell proliferation were obtained with immunohistochemical staining for neuronal marker doublecortin, confirming that diet and exploration affected hippocampal neurogenesis. Moreover, hippocampal levels of the brain-derived neurotrophic factor (BDNF) were increased in SUP rats as compared to SFF and DEF animals. We conclude that prenatal choline intake has enduring effects on adult hippocampal neurogenesis, possibly via up-regulation of BDNF levels, and suggest that these alterations of neurogenesis may contribute to the mechanism of life-long changes in cognitive function governed by the availability of choline during gestation. PMID:17445242

  2. Monte Carlo simulation for scanning technique with scattering foil free electron beam: A proof of concept study

    PubMed Central

    Sung, Wonmo; Park, Jong In; Kim, Jung-in; Carlson, Joel; Ye, Sung-Joon

    2017-01-01

    This study investigated the potential of a newly proposed scattering foil free (SFF) electron beam scanning technique for the treatment of skin cancer on the irregular patient surfaces using Monte Carlo (MC) simulation. After benchmarking of the MC simulations, we removed the scattering foil to generate SFF electron beams. Cylindrical and spherical phantoms with 1 cm boluses were generated and the target volume was defined from the surface to 5 mm depth. The SFF scanning technique with 6 MeV electrons was simulated using those phantoms. For comparison, volumetric modulated arc therapy (VMAT) plans were also generated with two full arcs and 6 MV photon beams. When the scanning resolution resulted in a larger separation between beams than the field size, the plan qualities were worsened. In the cylindrical phantom with a radius of 10 cm, the conformity indices, homogeneity indices and body mean doses of the SFF plans (scanning resolution = 1°) vs. VMAT plans were 1.04 vs. 1.54, 1.10 vs. 1.12 and 5 Gy vs. 14 Gy, respectively. Those of the spherical phantom were 1.04 vs. 1.83, 1.08 vs. 1.09 and 7 Gy vs. 26 Gy, respectively. The proposed SFF plans showed superior dose distributions compared to the VMAT plans. PMID:28493940

  3. Monte Carlo simulation for scanning technique with scattering foil free electron beam: A proof of concept study.

    PubMed

    Sung, Wonmo; Park, Jong In; Kim, Jung-In; Carlson, Joel; Ye, Sung-Joon; Park, Jong Min

    2017-01-01

    This study investigated the potential of a newly proposed scattering foil free (SFF) electron beam scanning technique for the treatment of skin cancer on the irregular patient surfaces using Monte Carlo (MC) simulation. After benchmarking of the MC simulations, we removed the scattering foil to generate SFF electron beams. Cylindrical and spherical phantoms with 1 cm boluses were generated and the target volume was defined from the surface to 5 mm depth. The SFF scanning technique with 6 MeV electrons was simulated using those phantoms. For comparison, volumetric modulated arc therapy (VMAT) plans were also generated with two full arcs and 6 MV photon beams. When the scanning resolution resulted in a larger separation between beams than the field size, the plan qualities were worsened. In the cylindrical phantom with a radius of 10 cm, the conformity indices, homogeneity indices and body mean doses of the SFF plans (scanning resolution = 1°) vs. VMAT plans were 1.04 vs. 1.54, 1.10 vs. 1.12 and 5 Gy vs. 14 Gy, respectively. Those of the spherical phantom were 1.04 vs. 1.83, 1.08 vs. 1.09 and 7 Gy vs. 26 Gy, respectively. The proposed SFF plans showed superior dose distributions compared to the VMAT plans.

  4. Soil CO2 evolution and root respiration in 11 year-old Loblolly Pine (Pinus taeda) Plantations as Affected by Moisture and Nutrient Availability

    Treesearch

    Chris A. Maier; L.W. Kress

    2000-01-01

    We measured soil CO2 evolution rates with (Sff) and without (Sms) the forest floor litter and root respiration monthly in 11-year-old loblolly pine (Pinus taeda L.) plantations during the fourth year of fertilization and irrigation treatments. Values of Sff...

  5. F0 Characteristics of Newsreaders on Varied Emotional Texts in Tamil Language.

    PubMed

    Gunasekaran, Nishanthi; Boominathan, Prakash; Seethapathy, Jayashree

    2017-12-26

    The objective of this study was to profile speaking F 0 and its variations in newsreaders on varied emotional texts. This study has a prospective, case-control study design. Fifteen professional newsreaders and 15 non-newsreaders were the participants. The participants read the news bulletin that conveyed different emotions (shock, neutral, happy, and sad) in a habitual and "newsreading" voice. Speaking fundamental frequency (SFF) and F 0 variations were extracted from 1620 tokens using Praat software (version 5.2.32) on the opening lines, headlines, news stories, and closing lines of each news item. Paired t test, independent t test, and Friedman test were used for statistical analysis. Both male and female newsreaders had significantly (P ≤ 0.05) higher SFFs and standard deviations (SDs) of SFF in newsreading voice than speaking voice. Female non-newsreaders demonstrated significantly higher SFF and SD of SFF in newsreading voice, whereas no significant differences were noticed in the frequency parameters for male non-newsreaders. No significant difference was noted in the frequency parameters of speaking and newsreading voice between male newsreaders and male non-newsreaders. A significant difference in the SD of SFF was noticed between female newsreaders and female non-newsreaders in newsreading voice. Female newsreaders had a higher frequency range in both speaking voice and newsreading voice when compared with non-newsreaders. F 0 characteristics and frequency range determine the amount of frequency changes exercised by newsreaders while reading bulletins. This information is highly pedagogic for training voices in this profession. Copyright © 2017 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  6. Regenerative Medicine and Restoration of Joint Function

    DTIC Science & Technology

    2012-10-01

    identify the parameters that generate anatomically shaped bone substitutes of optimal composition and structure with an articulating profile. 2) to develop...strengths. An in vivo study in rabbits to evaluate these materials are ongoing. Task 2. Optimization of SFF Rolling Compaction Parameters : The work is...ongoing related to optimizing SFF rolling compaction parameters to control the density of green samples. We have used CPP powders for these studies

  7. Use of iDXA spine scans to evaluate total and visceral abdominal fat.

    PubMed

    Bea, J W; Hsu, C-H; Blew, R M; Irving, A P; Caan, B J; Kwan, M L; Abraham, I; Going, S B

    2018-01-01

    Abdominal fat may be a better predictor than body mass index (BMI) for risk of metabolically-related diseases, such as diabetes, cardiovascular disease, and some cancers. We sought to validate the percent fat reported on dual energy X-ray absorptiometry (DXA) regional spine scans (spine fat fraction, SFF) against abdominal fat obtained from total body scans using the iDXA machine (General Electric, Madison, WI), as previously done on the Prodigy model. Total body scans and regional spine scans were completed on the same day (N = 50). In alignment with the Prodigy-based study, the following regions of interest (ROI) were assessed from total body scans and compared to the SFF from regional spine scans: total abdominal fat at (1) lumbar vertebrae L2-L4 and (2) L2-Iliac Crest (L2-IC); (3) total trunk fat; and (4) visceral fat in the android region. Separate linear regression models were used to predict each total body scan ROI from SFF; models were validated by bootstrapping. The sample was 84% female, a mean age of 38.5 ± 17.4 years, and mean BMI of 23.0 ± 3.8 kg/m 2 . The SFF, adjusted for BMI, predicted L2-L4 and L2-IC total abdominal fat (%; Adj. R 2 : 0.90) and total trunk fat (%; Adj. R 2 : 0.88) well; visceral fat (%) adjusted R 2 was 0.83. Linear regression models adjusted for additional participant characteristics resulted in similar adjusted R 2 values. This replication of the strong correlation between SFF and abdominal fat measures on the iDXA in a new population confirms the previous Prodigy model findings and improves generalizability. © 2017 Wiley Periodicals, Inc.

  8. MRT letter: Guided filtering of image focus volume for 3D shape recovery of microscopic objects.

    PubMed

    Mahmood, Muhammad Tariq

    2014-12-01

    In this letter, a shape from focus (SFF) method is proposed that utilizes the guided image filtering to enhance the image focus volume efficiently. First, image focus volume is computed using a conventional focus measure. Then each layer of image focus volume is filtered using guided filtering. In this work, the all-in-focus image, which can be obtained from the initial focus volume, is used as guidance image. Finally, improved depth map is obtained from the filtered image focus volume by maximizing the focus measure along the optical axis. The proposed SFF method is efficient and provides better depth maps. The improved performance is highlighted by conducting several experiments using image sequences of simulated and real microscopic objects. The comparative analysis demonstrates the effectiveness of the proposed SFF method. © 2014 Wiley Periodicals, Inc.

  9. Shape-from-focus by tensor voting.

    PubMed

    Hariharan, R; Rajagopalan, A N

    2012-07-01

    In this correspondence, we address the task of recovering shape-from-focus (SFF) as a perceptual organization problem in 3-D. Using tensor voting, depth hypotheses from different focus operators are validated based on their likelihood to be part of a coherent 3-D surface, thereby exploiting scene geometry and focus information to generate reliable depth estimates. The proposed method is fast and yields significantly better results compared with existing SFF methods.

  10. Surface properties and cytocompatibillity of silk fibroin films cast from aqueous solutions in different concentrations

    NASA Astrophysics Data System (ADS)

    Lian, Xiao-Jie; Wang, Song; Zhu, He-Sun

    2010-03-01

    Silk fibroin film (SFF) has been widely used in biomaterials. SFF is usually prepared from a regenerated silk aqueous solution and its properties depend remarkably on the preparation conditions. However, the effect of the silk fibroin concentration ( C 0) on the SFF surface properties as well as the cytocompatibility has rarely been investigated. In this work we prepared a series of Bombyx mori SFFs by casting SF aqueous solutions with the concentration from 10° to 102 mg/mL on TCPS substrate at 60°C. The test results of atomic force microscopy, attenuated total reflection Fourier transform infrared and contact angles analysis showed that the film surface roughness and β-sheet structure increased with the increase of C 0, whereas the surface hydrophilicity increased with the decrease of C 0. The in vitro clotting time measurement results revealed that the SFFs prepared from the thinner solution showed a longer APTT (activated partial thromboplastin time) and TT (thrombin time). The results of microscopy and MTT assay also revealed that cell adhesion and growth were enhanced on the SFF cast from lower C 0 for fibroblasts. In contrast, endothelial cells showed a similar behavior on all those films that were prepared from the solution in different concentrations.

  11. The Small-Angle Neutron Scattering Data Analysis of the Phospholipid Transport Nanosystem Structure

    NASA Astrophysics Data System (ADS)

    Zemlyanaya, E. V.; Kiselev, M. A.; Zhabitskaya, E. I.; Aksenov, V. L.; Ipatova, O. M.; Ivankov, O. I.

    2018-05-01

    The small-angle neutron scattering technique (SANS) is employed for investigation of structure of the phospholipid transport nanosystem (PTNS) elaborated in the V.N.Orekhovich Institute of Biomedical Chemistry (Moscow, Russia). The SANS spectra have been measured at the YuMO small-angle spectrometer of IBR-2 reactor (Joint Institute of Nuclear Research, Dubna, Russia). Basic characteristics of polydispersed population of PTNS unilamellar vesicles (average radius of vesicles, polydispersity, thickness of membrane, etc.) have been determined in three cases of the PTNS concentrations in D2O: 5%, 10%, and 25%. Numerical analysis is based on the separated form factors method (SFF). The results are discussed in comparison with the results of analysis of the small-angle X-ray scattering spectra collected at the Kurchatov Synchrotron Radiation Source of the National Research Center “Kurchatov Institute” (Moscow, Russia).

  12. MR signal-fat-fraction analysis and T2* weighted imaging measure BAT reliably on humans without cold exposure.

    PubMed

    Holstila, Milja; Pesola, Marko; Saari, Teemu; Koskensalo, Kalle; Raiko, Juho; Borra, Ronald J H; Nuutila, Pirjo; Parkkola, Riitta; Virtanen, Kirsi A

    2017-05-01

    Brown adipose tissue (BAT) is compositionally distinct from white adipose tissue (WAT) in terms of triglyceride and water content. In adult humans, the most significant BAT depot is localized in the supraclavicular area. Our aim is to differentiate brown adipose tissue from white adipose tissue using fat T2* relaxation time mapping and signal-fat-fraction (SFF) analysis based on a commercially available modified 2-point-Dixon (mDixon) water-fat separation method. We hypothesize that magnetic resonance (MR) imaging can reliably measure BAT regardless of the cold-induced metabolic activation, with BAT having a significantly higher water and iron content compared to WAT. The supraclavicular area of 13 volunteers was studied on 3T PET-MRI scanner using T2* relaxation time and SFF mapping both during cold exposure and at ambient temperature; and 18 F-FDG PET during cold exposure. Volumes of interest (VOIs) were defined semiautomatically in the supraclavicular fat depot, subcutaneous WAT and muscle. The supraclavicular fat depot (assumed to contain BAT) had a significantly lower SFF and fat T2* relaxation time compared to subcutaneous WAT. Cold exposure did not significantly affect MR-based measurements. SFF and T2* values measured during cold exposure and at ambient temperature correlated inversely with the glucose uptake measured by 18 F-FDG PET. Human BAT can be reliably and safely assessed using MRI without cold activation and PET-related radiation exposure. Copyright © 2017 Elsevier Inc. All rights reserved.

  13. Solid Freeform Fabrication: An Enabling Technology for Future Space Missions

    NASA Technical Reports Server (NTRS)

    Taminger, Karen M. B.; Hafley, Robert A.; Dicus, Dennis L.

    2002-01-01

    The emerging class of direct manufacturing processes known as Solid Freeform Fabrication (SFF) employs a focused energy beam and metal feedstock to build structural parts directly from computer aided design (CAD) data. Some variations on existing SFF techniques have potential for application in space for a variety of different missions. This paper will focus on three different applications ranging from near to far term to demonstrate the widespread potential of this technology for space-based applications. One application is the on-orbit construction of large space structures, on the order of tens of meters to a kilometer in size. Such structures are too large to launch intact even in a deployable design; their extreme size necessitates assembly or erection of such structures in space. A low-earth orbiting satellite with a SFF system employing a high-energy beam for high deposition rates could be employed to construct large space structures using feedstock launched from Earth. A second potential application is a small, multifunctional system that could be used by astronauts on long-duration human exploration missions to manufacture spare parts. Supportability of human exploration missions is essential, and a SFF system would provide flexibility in the ability to repair or fabricate any part that may be damaged or broken during the mission. The system envisioned would also have machining and welding capabilities to increase its utility on a mission where mass and volume are extremely limited. A third example of an SFF application in space is a miniaturized automated system for structural health monitoring and repair. If damage is detected using a low power beam scan, the beam power can be increased to perform repairs within the spacecraft or satellite structure without the requirement of human interaction or commands. Due to low gravity environment for all of these applications, wire feedstock is preferred to powder from a containment, handling, and safety standpoint. The energy beams may be either electron beam or laser, and the developments required for either energy source to achieve success in these applications will be discussed.

  14. Low-Cost WDM-PON With Colorless Bidirectional Transceivers

    NASA Astrophysics Data System (ADS)

    Shin, Dong Jae; Keh, Y. C.; Kwon, J. W.; Lee, E. H.; Lee, J. K.; Park, M. K.; Park, J. W.; Oh, Y. K.; Kim, S. W.; Yun, I. K.; Shin, H. C.; Heo, D.; Lee, J. S.; Shin, H. S.; Kim, H. S.; Park, S. B.; Jung, D. K.; Hwang, Seongtaek; Oh, Y. J.; Jang, D. H.; Shim, C. S.

    2006-01-01

    This paper presents a low-cost bidirectional (BiDi) wavelength-division-multiplexed passive optical network (WDM-PON) employing colorless uncooled BiDi transceivers (TRxs) and superluminescent diode (SLD)-based broadband light sources (BLSs). The C band is allocated for upstream and the E+ band for downstream in consideration of BiDi packaging, SLD development, and wavelength alignment of dual-window arrayed waveguide gratings (AWGs). The BiDi TRx integrates an uncooled Fabry-Pérot laser diode (FP-LD), a p-i-n photodiode (PD), and a 45°-angled thin-film filter in a small-form-factor (SFF) package. The SLD-based BLSs provide 13-dBm amplified spontaneous emissions (ASEs) with spectral ripples of < 3 dB and polarization dependencies of < 1 dB. Colorless operations over 32 100-GHz-spaced channels are demonstrated from -20 to 80°C in 155-Mb/s BiDi transmissions over 25 km.

  15. Application of optical 3D measurement on thin film buckling to estimate interfacial toughness

    NASA Astrophysics Data System (ADS)

    Jia, H. K.; Wang, S. B.; Li, L. A.; Wang, Z. Y.; Goudeau, P.

    2014-03-01

    The shape-from-focus (SFF) method has been widely studied as a passive depth recovery and 3D reconstruction method for digital images. An important step in SFF is the calculation of the focus level for different points in an image by using a focus measure. In this work, an image entropy-based focus measure is introduced into the SFF method to measure the 3D buckling morphology of an aluminum film on a polymethylmethacrylate (PMMA) substrate at a micro scale. Spontaneous film wrinkles and telephone-cord wrinkles are investigated after the deposition of a 300 nm thick aluminum film onto the PMMA substrate. Spontaneous buckling is driven by the highly compressive stress generated in the Al film during the deposition process. The interfacial toughness between metal films and substrates is an important parameter for the reliability of the film/substrate system. The height profiles of different sections across the telephone-cord wrinkle can be considered a straight-sided model with uniform width and height or a pinned circular model that has a delamination region characterized by a sequence of connected sectors. Furthermore, the telephone-cord geometry of the thin film can be used to calculate interfacial toughness. The instability of the finite element model is introduced to fit the buckling morphology obtained by SFF. The interfacial toughness is determined to be 0.203 J/m2 at a 70.4° phase angle from the straight-sided model and 0.105 J/m2 at 76.9° from the pinned circular model.

  16. Exploratory study of the association of steroid profiles in stimulated ovarian follicular fluid with outcomes of IVF treatment.

    PubMed

    Kushnir, Mark M; Naessén, Tord; Wanggren, Kjell; Hreinsson, Julius; Rockwood, Alan L; Meikle, A Wayne; Bergquist, Jonas

    2016-09-01

    Steroid concentrations in stimulated follicular fluid (sFF) samples have been linked to the quality of oocytes used in IVF treatments. Most of the published studies focused on evaluating the association of the IVF outcomes with only a few of the steroids, measured by immunoassays (IA). We performed a treatment outcome, prospective cohort study using stimulated FF sampled from 14 infertile women undergoing IVF treatment; single oocyte was used per IVF cycle. Fourteen endogenous steroids were analyzed in 22 ovarian follicle aspirations, which corresponded to the embryos used in the IVF. Ten oocytes were associated with live birth (LB) and 12 with no pregnancy (NP). Steroids were analyzed using liquid chromatography-tandem mass spectrometry (LC-MS/MS) methods. Differences in distribution of concentrations in association with the pregnancy outcome (LB or NP), and receiver operating characteristic (ROC) curves analysis were performed for the entire cohort and for within-women data. The predominant androgen and estrogen in stimulated sFF were androstenedione (A4) and estradiol (E2), respectively. Lower concentrations of pregnenolone (Pr), lower ratios of A4/ dehydroepiandrosterone (DHEA), testosterone (Te)/DHEA, and greater ratios of E2/Te, and estrone/A4 were observed in sFF samples associated with LB. Among the oocytes associated with NP, in four out of 12 samples total concentration of androgens was above the distribution of the concentrations in the oocytes corresponding to the LB group. Observations of the study indicated increased consumption of precursors and increased biosynthesis of estrogens in the follicles associated with LB. Our data suggest that potentially steroid profiles in sFF obtained during oocyte retrieval may serve as biomarkers for selection of the best embryo to transfer after IVF. Copyright © 2015 Elsevier Ltd. All rights reserved.

  17. Influence of Concentration and Salinity on the Biodegradability of Organic Additives in Hydraulic Fracturing Fluid

    NASA Astrophysics Data System (ADS)

    Mouser, P. J.; Kekacs, D.

    2014-12-01

    One of the risks associated with the use of hydraulic fracturing technologies for energy development is the potential release of hydraulic fracturing-related fluids into surface waters or shallow aquifers. Many of the organic additives used in hydraulic fracturing fluids are individually biodegradable, but little is know on how they will attenuate within a complex organic fluid in the natural environment. We developed a synthetic hydraulic fracturing fluid based on disclosed recipes used by Marcellus shale operators to evaluate the biodegradation potential of organic additives across a concentration (25 to 200 mg/L DOC) and salinity gradient (0 to 60 g/L) similar to Marcellus shale injected fluids. In aerobic aqueous solutions, microorganisms removed 91% of bulk DOC from low SFF solutions and 57% DOC in solutions having field-used SFF concentrations within 7 days. Under high SFF concentrations, salinity in excess of 20 g/L inhibited organic compound biodegradation for several weeks, after which time the majority (57% to 75%) of DOC remained in solution. After SFF amendment, the initially biodiverse lake or sludge microbial communities were quickly dominated (>79%) by Pseudomonas spp. Approximately 20% of added carbon was converted to biomass while the remainder was respired to CO2 or other metabolites. Two alcohols, isopropanol and octanol, together accounted for 2-4% of the initial DOC, with both compounds decreasing to below detection limits within 7 days. Alcohol degradation was associated with an increase in acetone at mg/L concentrations. These data help to constrain the biodegradation potential of organic additives in hydraulic fracturing fluids and guide our understanding of the microbial communities that may contribute to attenuation in surface waters.

  18. Anaerobic Biodegradation of Ethylene Glycol within Hydraulic Fracturing Fluid

    NASA Astrophysics Data System (ADS)

    Heyob, K. M.; Mouser, P. J.

    2014-12-01

    Ethylene glycol (EG) is a commonly used organic additive in hydraulic fracturing fluids used for shale gas recovery. Under aerobic conditions, this compound readily biodegrades to acetate and CO2 or is oxidized through the glycerate pathway. In the absence of oxygen, organisms within genera Desulfovibrio, Acetobacterium, and others can transform EG to acetaldehyde, a flammable and suspected carcinogenic compound. Acetaldehyde can then be enzymatically degraded to ethanol or acetate and CO2. However, little is known on how EG degrades in the presence of other organic additives, particularly under anaerobic conditions representative of deep groundwater aquifers. To better understand the fate and attenuation of glycols within hydraulic fracturing fluids we are assessing their biodegradation potential and pathways in batch anaerobic microcosm treatments. Crushed Berea sandstone was inoculated with groundwater and incubated with either EG or a synthetic fracturing fluid (SFF) containing EG formulations. We tracked changes in dissolved organic carbon (DOC), EG, and its transformation products over several months. Approximately 41% of bulk DOC in SFF is degraded within 21 days, with 58% DOC still remaining after 63 days. By comparison, this same SFF degrades by 70% within 25 days when inoculated with sediment-groundwater microbial communities, suggesting that bulk DOC degradation occurs at a slower rate and to a lesser extent with bedrock. Aerobic biodegradation of EG occurs rapidly (3-7 days); however anaerobic degradation of EG is much slower, requiring several weeks for substantial DOC loss to be observed. Ongoing experiments are tracking the degradation pathways of EG alone and in the presence of SFF, with preliminary data showing incomplete glycol transformation within the complex hydraulic fracturing fluid mixture. This research will help to elucidate rates, processes, and pathways for EG biodegradation and identify key microbial taxa involved in its degradation.

  19. Advancements in Binder Systems for Solid Freeform Fabrication

    NASA Technical Reports Server (NTRS)

    Cooper, Ken; Munafo, Paul (Technical Monitor)

    2002-01-01

    Paper will present recent developments in advanced material binder systems for solid freeform fabrication (SFF) technologies. The advantage of SFF is the capability to custom fabricate complex geometries directly from computer aided design data in layer- by-layer fashion, eliminated the need for traditional fixturing and tooling. Binders allow for the low temperature processing of 'green' structural materials, either metal, ceramic or composite, in traditional rapid prototyping machines. The greatest obstacle comes when green parts must then go through a sintering or burnout process to remove the binders and fully densify the parent material, without damaging or distorting the original part geometry. Critical issues and up-to-date assessments will be delivered on various material systems.

  20. Enhancement of Optical Adaptive Sensing by Using a Dual-Stage Seesaw-Swivel Actuator with a Tunable Vibration Absorber

    PubMed Central

    Chou, Po-Chien; Lin, Yu-Cheng; Cheng, Stone

    2011-01-01

    Technological obstacles to the use of rotary-type swing arm actuators to actuate optical pickup modules in small-form-factor (SFF) disk drives stem from a hinge’s skewed actuation, subsequently inducing off-axis aberrations and deteriorating optical quality. This work describes a dual-stage seesaw-swivel actuator for optical pickup actuation. A triple-layered bimorph bender made of piezoelectric materials (PZTs) is connected to the suspension of the pickup head, while the tunable vibration absorber (TVA) unit is mounted on the seesaw swing arm to offer a balanced force to reduce vibrations in a focusing direction. Both PZT and TVA are designed to satisfy stable focusing operation operational requirements and compensate for the tilt angle or deformation of a disc. Finally, simulation results verify the performance of the dual-stage seesaw-swivel actuator, along with experimental procedures and parametric design optimization confirming the effectiveness of the proposed system. PMID:22163877

  1. Semen parameters in fertile US men: the Study for Future Families.

    PubMed

    Redmon, J B; Thomas, W; Ma, W; Drobnis, E Z; Sparks, A; Wang, C; Brazil, C; Overstreet, J W; Liu, F; Swan, S H

    2013-11-01

    Establishing reference norms for semen parameters in fertile men is important for accurate assessment, counselling and treatment of men with male factor infertility. Identifying temporal or geographic variability in semen quality also requires accurate measurement of semen parameters in well-characterized, defined populations of men. The Study for Future Families (SFF) recruited men who were partners of pregnant women attending prenatal clinics in Los Angeles CA, Minneapolis MN, Columbia MO, New York City NY and Iowa City IA. Semen samples were collected on site from 763 men (73% White, 15% Hispanic/Latino, 7% Black and 5% Asian or other ethnic group) using strict quality control and well-defined protocols. Semen volume (by weight), sperm concentration (hemacytometer) and sperm motility were measured at each centre. Sperm morphology (both WHO, 1999 strict and WHO, 1987) was determined at a central laboratory. Mean abstinence was 3.2 days. Mean (median; 5th-95th percentile) values were: semen volume, 3.9 (3.7; 1.5-6.8) mL; sperm concentration, 60 (67; 12-192) × 10(6) /mL; total sperm count 209 (240; 32-763) × 10(6) ; % motile, 51 (52; 28-67) %; and total motile sperm count, 104 (128; 14-395) × 10(6) respectively. Values for sperm morphology were 11 (10; 3-20) % and 57 (59; 38-72) % normal forms for WHO (1999) (strict) and WHO (1987) criteria respectively. Black men had significantly lower semen volume, sperm concentration and total motile sperm counts than White and Hispanic/Latino men. Semen parameters were marginally higher in men who achieved pregnancy more quickly but differences were small and not statistically significant. The SFF provides robust estimates of semen parameters in fertile men living in five different geographic locations in the US. Fertile men display wide variation in all of the semen parameters traditionally used to assess fertility potential. © 2013 American Society of Andrology and European Academy of Andrology.

  2. Essential oils from Schinus species of northwest Argentina: Composition and antifungal activity.

    PubMed

    Sampietro, Diego A; Belizana, Maria Melina E; Baptista, Zareath P Terán; Vattuone, Marta A; Catalán, Cesar A N

    2014-07-01

    The composition of the essential oils from leaves (Sal) and fruits of S. areira (Saf), and fruits of S. fasciculatus (Sff) and S. gracilipes (Sgf) were analyzed by GC/MS. The major compounds identified were sabinene (26.0 +/- 0.5%), bicyclogermacrene (14.5 +/- 0.4%), and E-citral (6.7+/- 0.2%) in Sal oil, limonene (27.7 +/- 0.7%), sabinene (16.0+/- 0.5%), beta-phellandrene (14.6 +/- 0.8%) and bicyclogermacrene (8.1 +/- 0.2%) in Saf oil, sabinene (22.7 +/- 0.6%), alpha-phellandrene (18.7 +/- 0.3%), beta-phellandrene (15.7 +/- 0.4%), and bicyclogermacrene (8.1 +/- 0.2%) in Sff oil and beta-pinene (25.4 +/- 0.8%), alpha-pinene (24.7 +/- 0.7%), and sabinene (13.6 +/- 0.4%) in Sgf oil.The antifungal activity of the four oils was evaluated on strains of Fusarium verticillioides and F. graminearum, and the results compared with the effect of epoxyconazole, pyraclostrobin and thyme oil. The Sff oil had the highest antifungal activity among the Schinus oils tested, with MIC100 (F. graminearum) = 6 per thousand and MIC100 (F. verticillioides) = 12 per thousand. A principal component analysis suggests that 9 constituents (alpha-thujene, alpha-terpinene, p-cymene, gamma-terpinene, terpinolene, 1-terpineol, alpha-calacorene, alpha-phellandrene, and terpinen-4-ol) explain the higher antifungal effect of Sff. The MIC100s of Schinus oils were on average 30-60 and 8.5-17 fold lower than those obtained for thyme oil on F. verticillioides and F. graminearum, respectively. In the case of commercial fungicides, their MIC100s were three orders of magnitude lower than those of Schinus oils. The last ones showed an additive interaction when assayed in mixtures with the commecial fungicides and thyme oil. The results suggest that the doses of fungicides required for control of the Fusarium species can be reduced when they are assayed in mixtures with the Schinus oils.

  3. Influence of Layer-by-Layer Polyelectrolyte Deposition and EDC/NHS Activated Heparin Immobilization onto Silk Fibroin Fabric

    PubMed Central

    Elahi, M. Fazley; Guan, Guoping; Wang, Lu; King, Martin W.

    2014-01-01

    To enhance the hemocompatibility of silk fibroin fabric as biomedical material, polyelectrolytes architectures have been assembled through the layer-by-layer (LbL) technique on silk fibroin fabric (SFF). In particular, 1.5 and 2.5 bilayer of oppositely charged polyelectrolytes were assembled onto SFF using poly(allylamine hydrochloride) (PAH) as polycationic polymer and poly(acrylic acid) (PAA) as polyanionic polymer with PAH topmost. Low molecular weight heparin (LMWH) activated with 1-ethyl-3-(dimethylaminopropyl) carbodiimide hydrochloride (EDC) and N-hydroxysuccinimide (NHS) was then immobilized on its surface. Alcian Blue staining, toluidine blue assay and X-ray photoelectron spectroscopy (XPS) confirmed the presence of heparin on modified SFF surfaces. The surface morphology of the modified silk fibroin fabric surfaces was characterized by scanning electron microscopy (SEM) and atomic force microscopy (AFM), and obtained increased roughness. Negligible hemolytic effect and a higher concentration of free hemoglobin by a kinetic clotting time test ensured the improved biological performance of the modified fibroin fabric. Overall, the deposition of 2.5 bilayer was found effective in terms of biological and surface properties of the modified fibroin fabric compared to 1.5 bilayer self-assembly technique. Therefore, this novel approach to surface modification may demonstrate long term patency in future in vivo animal trials of small diameter silk fibroin vascular grafts. PMID:28788601

  4. Flex-rigid pleuroscopic biopsy with the SB knife Jr is a novel technique for diagnosis of malignant or benign fibrothorax.

    PubMed

    Wang, Xiao-Bo; Yin, Yan; Miao, Yuan; Eberhardt, Ralf; Hou, Gang; Herth, Felix J; Kang, Jian

    2016-11-01

    Diagnosing pleural effusion is challenging, especially in patients with malignant or benign fibrothorax, which is difficult to sample using standard flexible forceps (SFF) via flex-rigid pleuroscopy. An adequate sample is crucial for the differential diagnosis of malignant fibrothorax (malignant pleural mesothelioma, metastatic lung carcinoma, etc.) from benign fibrothorax (benign asbestos pleural disease, tuberculous pleuritis, etc.). Novel biopsy techniques are required in flex-rigid pleuroscopy to improve the sample size and quality. The SB knife Jr, which is a scissor forceps that uses a mono-pole high frequency, was developed to allow convenient and accurate resection of larger lesions during endoscopic dissection (ESD). Herein, we report two patients with fibrothorax who underwent a pleural biopsy using an SB knife Jr to investigate the potential use of this tool in flex-rigid pleuroscopy when pleural lesions are difficult to biopsy via SFF. The biopsies were successful, with sufficient size and quality for definitive diagnosis. We also successfully performed adhesiolysis with the SB knife Jr in one case, and adequate biopsies were conducted. No complications were observed. Electrosurgical biopsy with the SB knife Jr during flex-rigid pleuroscopy allowed us to obtain adequate samples for the diagnosis of malignant versus benign fibrothorax, which is usually not possible with SFF. The SB knife Jr also demonstrated a potential use for pleuropulmonary adhesions.

  5. Low cost, small form factor, and integration as the key features for the optical component industry takeoff

    NASA Astrophysics Data System (ADS)

    Schiattone, Francesco; Bonino, Stefano; Gobbi, Luigi; Groppi, Angelamaria; Marazzi, Marco; Musio, Maurizio

    2003-04-01

    In the past the optical component market has been mainly driven by performances. Today, as the number of competitors has drastically increased, the system integrators have a wide range of possible suppliers and solutions giving them the possibility to be more focused on cost and also on footprint reduction. So, if performances are still essential, low cost and Small Form Factor issues are becoming more and more crucial in selecting components. Another evolution in the market is the current request of the optical system companies to simplify the supply chain in order to reduce the assembling and testing steps at system level. This corresponds to a growing demand in providing subassemblies, modules or hybrid integrated components: that means also Integration will be an issue in which all the optical component companies will compete to gain market shares. As we can see looking several examples offered by electronic market, to combine low cost and SFF is a very challenging task but Integration can help in achieving both features. In this work we present how these issues could be approached giving examples of some advanced solutions applied to LiNbO3 modulators. In particular we describe the progress made on automation, new materials and low cost fabrication methods for the parts. We also introduce an approach in integrating optical and electrical functionality on LiNbO3 modulators including RF driver, bias control loop, attenuator and photodiode integrated in a single device.

  6. Effects of singing training on the speaking voice of voice majors.

    PubMed

    Mendes, Ana P; Brown, W S; Rothman, Howard B; Sapienza, Christine

    2004-03-01

    This longitudinal study gathered data with regard to the question: Does singing training have an effect on the speaking voice? Fourteen voice majors (12 females and two males; age range 17 to 20 years) were recorded once a semester for four consecutive semesters, while sustaining vowels and reading the "Rainbow Passage." Acoustic measures included speaking fundamental frequency (SFF) and sound pressure level (SLP). Perturbation measures included jitter, shimmer, and harmonic-to-noise ratio. Temporal measures included sentence, consonant, and diphthong durations. Results revealed that, as the number of semesters increased, the SFF increased while jitter and shimmer slightly decreased. Repeated measure analysis, however, indicated that none of the acoustic, temporal, or perturbation differences were statistically significant. These results confirm earlier cross-sectional studies that compared singers with nonsingers, in that singing training mostly affects the singing voice and rarely the speaking voice.

  7. Multi range spectral feature fitting for hyperspectral imagery in extracting oilseed rape planting area

    NASA Astrophysics Data System (ADS)

    Pan, Zhuokun; Huang, Jingfeng; Wang, Fumin

    2013-12-01

    Spectral feature fitting (SFF) is a commonly used strategy for hyperspectral imagery analysis to discriminate ground targets. Compared to other image analysis techniques, SFF does not secure higher accuracy in extracting image information in all circumstances. Multi range spectral feature fitting (MRSFF) from ENVI software allows user to focus on those interesting spectral features to yield better performance. Thus spectral wavelength ranges and their corresponding weights must be determined. The purpose of this article is to demonstrate the performance of MRSFF in oilseed rape planting area extraction. A practical method for defining the weighted values, the variance coefficient weight method, was proposed to set up criterion. Oilseed rape field canopy spectra from the whole growth stage were collected prior to investigating its phenological varieties; oilseed rape endmember spectra were extracted from the Hyperion image as identifying samples to be used in analyzing the oilseed rape field. Wavelength range divisions were determined by the difference between field-measured spectra and image spectra, and image spectral variance coefficient weights for each wavelength range were calculated corresponding to field-measured spectra from the closest date. By using MRSFF, wavelength ranges were classified to characterize the target's spectral features without compromising spectral profile's entirety. The analysis was substantially successful in extracting oilseed rape planting areas (RMSE ≤ 0.06), and the RMSE histogram indicated a superior result compared to a conventional SFF. Accuracy assessment was based on the mapping result compared with spectral angle mapping (SAM) and the normalized difference vegetation index (NDVI). The MRSFF yielded a robust, convincible result and, therefore, may further the use of hyperspectral imagery in precision agriculture.

  8. Effect of Korea red ginseng on the blood pressure in conscious hypertensive rats.

    PubMed

    Jeon, B H; Kim, C S; Park, K S; Lee, J W; Park, J B; Kim, K J; Kim, S H; Chang, S J; Nam, K Y

    2000-09-01

    The change of blood pressure and heart rate after intravenous injection of Korea red ginseng (KRG) were studied in the conscious normotensive and one-kidney, one-clip Goldblatt hypertensive (1K, 1C-GBH) rats. Crude saponin (CS) of KRG (50, 100 mg/kg i.v.) induced a hypotensive effect and bradycardia in a dose-dependent manner in the anesthetized rats. On the other hand, CS of KRG (100 mg/kg) induced a hypotensive effect and reflex tachycardia in the conscious rats. Saponin-free fraction (SFF) of KRG did not affect them in the anesthetized normotensive rats (P>.05). The maximal hypotensive effect by CS of KRG in the conscious 1K, 1C-GBH hypertensive rats and L-nitroarginine methyl ester (L-NAME, 40 mg/kg)-treated conscious hypertensive rats was not different from that of conscious normotensive rats (Delta 31.6+/-6.3, Delta 27.5+/-5.8 vs. Delta 26.7+/-4.3 mmHg, P>.05). However, pretreatment of L-NAME significantly inhibited the reflex tachycardia by CS of KRG (70.8+/-7.0 vs. 30.6+/-15.0 bpm, P<.05). Hemolysate-sensitive nitric oxide (NO) current by the CS of KRG was greater than that of the SFF of KRG (651.9+/-128.2 pA for CS and 164.9+/-92.5 pA for SFF, P<.001). These findings suggest that KRG has a hypotensive effect and its effect may be due to saponin fraction of KRG in the conscious rats. The releasing effect of NO of KRG, like NO donor, may be partly contributed to the hypotensive effect of KRG.

  9. Interannual variation in rainfall, drought stress and seedling mortality may mediate monodominance in tropical flooded forests.

    PubMed

    Lopez, Omar R; Kursar, Thomas A

    2007-11-01

    Flood tolerance is commonly regarded as the main factor explaining low diversity and monodominance in tropical swamps. In this study we examined seedling mortality in relation to seasonality, i.e., flooding versus drought, of the dominant tree species (Prioria copaifera), and three associated species (Pterocarpus officinalis, Carapa guianensis and Pentaclethra macroloba), in seasonally flooded forests (SFF) in Darien, Panama. Seedling mortality differed among species, years and seasons. Prioria seedlings experienced the lowest overall mortality, and after 3 years many more Prioria seedlings remained alive than those of any of the associated species. In general, within species, larger seedlings had greater survival. Seed size, which can vary by close to 2 orders of magnitude in Prioria, had a confounding effect with that of topography. Large-seeded Prioria seedlings experienced 1.5 times greater mortality than small-seeded seedlings, as large-seeded Prioria seedlings were more likely to be located in depressions. This finding suggests that seed size, plant size and topography are important in understanding SFF regeneration. For all species, seedling mortality was consistently greater during the dry season than during flooding. For Prioria, dry season seedling mortality was correlated with drought stress, that is, high mortality during the long El Niño dry season of 1998 and the normal dry season of 2000, but very low dry season mortality during the mild dry season of 1999. Prioria's ability to dominate in seasonally flooded forest of Central America is partly explained by its low drought-related mortality in comparison to associated species.

  10. Type 3 Thyroplasty for a Patient with Female-to-Male Gender Identity Disorder.

    PubMed

    Saito, Yu; Nakamura, Kazuhiro; Itani, Shigeto; Tsukahara, Kiyoaki

    2018-01-01

    In most cases, about the voice of the patient with female-to-male/gender identity disorder (FTM/GID), hormone therapy makes the voice low-pitched. In success cases, there is no need for phonosurgery. However, hormone therapy is not effective in some cases. We perform type 3 thyroplasty in these cases. Hormone therapy was started in 2008 but did not lower the speaking fundamental frequencies (SFFs). We therefore performed TP3 under local anesthesia. In our case, the SFF at the first visit was 146 Hz. The postoperative SFF was 110 Hz. TP3 was performed under local anesthesia in a patient with FTM/GID in whom hormone therapy proved ineffective. With successful conversion to a lower-pitched voice, the patient could begin to live daily life as a male. QOL improved significantly with TP3. If hormone therapy proves ineffective, TP3 may be selected as an optional treatment and appears to show few surgical complications and was, in this case, a very effective treatment.

  11. 6 DOF synchronized control for spacecraft formation flying with input constraint and parameter uncertainties.

    PubMed

    Lv, Yueyong; Hu, Qinglei; Ma, Guangfu; Zhou, Jiakang

    2011-10-01

    This paper treats the problem of synchronized control of spacecraft formation flying (SFF) in the presence of input constraint and parameter uncertainties. More specifically, backstepping based robust control is first developed for the total 6 DOF dynamic model of SFF with parameter uncertainties, in which the model consists of relative translation and attitude rotation. Then this controller is redesigned to deal with the input constraint problem by incorporating a command filter such that the generated control could be implementable even under physical or operating constraints on the control input. The convergence of the proposed control algorithms is proved by the Lyapunov stability theorem. Compared with conventional methods, illustrative simulations of spacecraft formation flying are conducted to verify the effectiveness of the proposed approach to achieve the spacecraft track the desired attitude and position trajectories in a synchronized fashion even in the presence of uncertainties, external disturbances and control saturation constraint. Copyright © 2011 ISA. Published by Elsevier Ltd. All rights reserved.

  12. Enhancing Sustainability Curricula through Faculty Learning Communities

    ERIC Educational Resources Information Center

    Natkin, L. W.; Kolbe, Tammy

    2016-01-01

    Purpose: Although the number of higher education institutions adopting sustainability-focused faculty learning communities (FLCs) has grown, very few of these programs have published evaluation research. This paper aims to report findings from an evaluation of the University of Vermont's (UVM's) sustainability faculty fellows (SFF) program. It…

  13. Bion M1. Peculiarities of life activities of microbes in 30-day spaceflight

    NASA Astrophysics Data System (ADS)

    Viacheslav, Ilyin; Korshunov, Denis; Morozova, Julia; Voeikova, Tatiana; Tyaglov, Boris; Novikova, Liudmila; Krestyanova, Irina; Emelyanova, Lydia

    The aim of this work was to analyze the influence of space flight factors ( SFF) to microorganism strains , exposed inside unmanned spacecraft Bion M-1 during the 30- day space flight. Objectives of the work - the study of the influence of the SFF exchange chromosomal DNA in crosses microorganisms of the genus Streptomyces; the level of spontaneous phage induction of lysogenic strains fS31 from Streptomyces lividans 66 and Streptomyces coelicolor A3 ( 2 ) on the biosynthesis of the antibiotic tylosin strain of Streptomyces fradiae; survival electrogenic bacteria Shewanella oneidensis MR- 1 is used in the microbial fuel cell As a result of this work it was found that the SFF affect the exchange of chromosomal DNA by crossing strains of Streptomyces. Was detected polarity crossing , expressed in an advantageous contribution chromosome fragment of one of the parent strains in recombinant offspring. This fact may indicate a more prolonged exposure of cells in microgravity and , as a consequence, the transfer of longer fragments of chromosomal DNA This feature is the transfer of genetic material in microgravity could lead to wider dissemination and horizontal transfer of chromosomal and plasmid DNA of symbiotic microflora astronauts and other strains present in the spacecraft. It was shown no effect on the frequency of recombination PCF and the level of mutation model reversion of auxotrophic markers to prototrophy It was demonstrated that PCF increase the level of induction of cell actinophage fS31 lysogenic strain of S. lividans 66, but did not affect the level of induction of this phage cells S. coelicolor A3 ( 2). It is shown that the lower the level of synthesis PCF antibiotic aktinorodina (actinorhodin) in lysogenic strain S. coelicolor A3 ( 2). 66 Strains of S. lividans and S. coelicolor A3 ( 2 ) can be used as a biosensor for studying the effect on microorganisms PCF It is shown that the effect of the PCF reduces synthesis of tylosin and desmicosyn S. fradiae at about 30 % as compared with the synchronous control, but the ratio of desmycosine to tylosin does not change. It was estimated that the strain S. oneidensis MR- 1 under the conditions of flight remains viable in all types of culture media Reducing the level of activity of the cells is similar in flight samples and the laboratory strain Strain S. oneidensis MR- 1 can be used in the microbial fuel cell while conducting experiments on board the spacecraft

  14. The Impact of Special Focus Facility Nursing Homes on Market Quality

    ERIC Educational Resources Information Center

    Castle, Nicholas G.; Sonon, Kristen; Antonova, Jenya

    2010-01-01

    Purpose: Special Focus Facilities (SFFs) are nursing facilities designated by the Centers for Medicare & Medicaid Services to be of chronic poor quality. Relatively few nursing facilities are included in this initiative. The purpose of this research was to examine whether nursing facilities included in the 2007 SFF initiative subsequently…

  15. An Examination of Special Focus Facility Nursing Homes

    ERIC Educational Resources Information Center

    Castle, Nicholas G.; Engberg, John

    2010-01-01

    Purpose: Nursing facilities that are determined to have a greater number of quality problems, more serious problems than average, and a demonstrated pattern of quality problems are included in the Special Focus Facility (SFF) initiative. The purpose of this research was to provide descriptive information on these SFFs and to examine the quality…

  16. Application of linear multifrequency-grey acceleration to preconditioned Krylov iterations for thermal radiation transport

    DOE PAGES

    Till, Andrew T.; Warsa, James S.; Morel, Jim E.

    2018-06-15

    The thermal radiative transfer (TRT) equations comprise a radiation equation coupled to the material internal energy equation. Linearization of these equations produces effective, thermally-redistributed scattering through absorption-reemission. In this paper, we investigate the effectiveness and efficiency of Linear-Multi-Frequency-Grey (LMFG) acceleration that has been reformulated for use as a preconditioner to Krylov iterative solution methods. We introduce two general frameworks, the scalar flux formulation (SFF) and the absorption rate formulation (ARF), and investigate their iterative properties in the absence and presence of true scattering. SFF has a group-dependent state size but may be formulated without inner iterations in the presence ofmore » scattering, while ARF has a group-independent state size but requires inner iterations when scattering is present. We compare and evaluate the computational cost and efficiency of LMFG applied to these two formulations using a direct solver for the preconditioners. Finally, this work is novel because the use of LMFG for the radiation transport equation, in conjunction with Krylov methods, involves special considerations not required for radiation diffusion.« less

  17. Assessment of infant formula quality and composition using Vis-NIR, MIR and Raman process analytical technologies.

    PubMed

    Wang, Xiao; Esquerre, Carlos; Downey, Gerard; Henihan, Lisa; O'Callaghan, Donal; O'Donnell, Colm

    2018-06-01

    In this study, visible and near-infrared (Vis-NIR), mid-infrared (MIR) and Raman process analytical technologies were investigated for assessment of infant formula quality and compositional parameters namely preheat temperature, storage temperature, storage time, fluorescence of advanced Maillard products and soluble tryptophan (FAST) index, soluble protein, fat and surface free fat (SFF) content. PLS-DA models developed using spectral data with appropriate data pre-treatment and significant variables selected using Martens' uncertainty test had good accuracy for the discrimination of preheat temperature (92.3-100%) and storage temperature (91.7-100%). The best PLS regression models developed yielded values for the ratio of prediction error to deviation (RPD) of 3.6-6.1, 2.1-2.7, 1.7-2.9, 1.6-2.6 and 2.5-3.0 for storage time, FAST index, soluble protein, fat and SFF content prediction respectively. Vis-NIR, MIR and Raman were demonstrated to be potential PAT tools for process control and quality assurance applications in infant formula and dairy ingredient manufacture. Copyright © 2018 Elsevier B.V. All rights reserved.

  18. Uncertainty indication in soil function maps - transparent and easy-to-use information to support sustainable use of soil resources

    NASA Astrophysics Data System (ADS)

    Greiner, Lucie; Nussbaum, Madlene; Papritz, Andreas; Zimmermann, Stephan; Gubler, Andreas; Grêt-Regamey, Adrienne; Keller, Armin

    2018-05-01

    Spatial information on soil function fulfillment (SFF) is increasingly being used to inform decision-making in spatial planning programs to support sustainable use of soil resources. Soil function maps visualize soils abilities to fulfill their functions, e.g., regulating water and nutrient flows, providing habitats, and supporting biomass production based on soil properties. Such information must be reliable for informed and transparent decision-making in spatial planning programs. In this study, we add to the transparency of soil function maps by (1) indicating uncertainties arising from the prediction of soil properties generated by digital soil mapping (DSM) that are used for soil function assessment (SFA) and (2) showing the response of different SFA methods to the propagation of uncertainties through the assessment. For a study area of 170 km2 in the Swiss Plateau, we map 10 static soil sub-functions for agricultural soils for a spatial resolution of 20 × 20 m together with their uncertainties. Mapping the 10 soil sub-functions using simple ordinal assessment scales reveals pronounced spatial patterns with a high variability of SFF scores across the region, linked to the inherent properties of the soils and terrain attributes and climate conditions. Uncertainties in soil properties propagated through SFA methods generally lead to substantial uncertainty in the mapped soil sub-functions. We propose two types of uncertainty maps that can be readily understood by stakeholders. Cumulative distribution functions of SFF scores indicate that SFA methods respond differently to the propagated uncertainty of soil properties. Even where methods are comparable on the level of complexity and assessment scale, their comparability in view of uncertainty propagation might be different. We conclude that comparable uncertainty indications in soil function maps are relevant to enable informed and transparent decisions on the sustainable use of soil resources.

  19. Monolithic integrated optic fiber Bragg grating sensor interrogator

    NASA Astrophysics Data System (ADS)

    Mendoza, Edgar A.; Esterkin, Yan; Kempen, Cornelia; Sun, Songjian

    2010-04-01

    Fiber Bragg gratings (FBGs) are a mature sensing technology that has gained rapid acceptance in civil, aerospace, chemical and petrochemical, medicine, aviation and automotive industries. Fiber Bragg grating sensors can be use for a variety of measurements including strain, stress, vibration, acoustics, acceleration, pressure, temperature, moisture, and corrosion distributed at multiple locations within the structure using a single fiber element. The most prominent advantages of FBGs are: small size and light weight, multiple FBG transducers on a single fiber, and immunity to radio frequency interference. A major disadvantage of FBG technology is that conventional state-of-the-art fiber Bragg grating interrogation systems are typically bulky, heavy, and costly bench top instruments that are assembled from off-the-shelf fiber optic and optical components integrated with a signal electronics board into an instrument console. Based on the need for a compact FBG interrogation system, this paper describes recent progress towards the development of a miniature fiber Bragg grating sensor interrogator (FBG-TransceiverTM) system based on multi-channel monolithic integrated optic sensor microchip technology. The integrated optic microchip technology enables the monolithic integration of all of the functionalities, both passive and active, of conventional bench top FBG sensor interrogators systems, packaged in a miniaturized, low power operation, 2-cm x 5-cm small form factor (SFF) package suitable for the long-term structural health monitoring in applications where size, weight, and power are critical for operation.

  20. Comparing the accuracy of perturbative and variational calculations for predicting fundamental vibrational frequencies of dihalomethanes

    NASA Astrophysics Data System (ADS)

    Krasnoshchekov, Sergey V.; Schutski, Roman S.; Craig, Norman C.; Sibaev, Marat; Crittenden, Deborah L.

    2018-02-01

    Three dihalogenated methane derivatives (CH2F2, CH2FCl, and CH2Cl2) were used as model systems to compare and assess the accuracy of two different approaches for predicting observed fundamental frequencies: canonical operator Van Vleck vibrational perturbation theory (CVPT) and vibrational configuration interaction (VCI). For convenience and consistency, both methods employ the Watson Hamiltonian in rectilinear normal coordinates, expanding the potential energy surface (PES) as a Taylor series about equilibrium and constructing the wavefunction from a harmonic oscillator product basis. At the highest levels of theory considered here, fourth-order CVPT and VCI in a harmonic oscillator basis with up to 10 quanta of vibrational excitation in conjunction with a 4-mode representation sextic force field (SFF-4MR) computed at MP2/cc-pVTZ with replacement CCSD(T)/aug-cc-pVQZ harmonic force constants, the agreement between computed fundamentals is closer to 0.3 cm-1 on average, with a maximum difference of 1.7 cm-1. The major remaining accuracy-limiting factors are the accuracy of the underlying electronic structure model, followed by the incompleteness of the PES expansion. Nonetheless, computed and experimental fundamentals agree to within 5 cm-1, with an average difference of 2 cm-1, confirming the utility and accuracy of both theoretical models. One exception to this rule is the formally IR-inactive but weakly allowed through Coriolis-coupling H-C-H out-of-plane twisting mode of dichloromethane, whose spectrum we therefore revisit and reassign. We also investigate convergence with respect to order of CVPT, VCI excitation level, and order of PES expansion, concluding that premature truncation substantially decreases accuracy, although VCI(6)/SFF-4MR results are still of acceptable accuracy, and some error cancellation is observed with CVPT2 using a quartic force field.

  1. Performance enhancement of iron-chromium redox flow batteries by employing interdigitated flow fields

    NASA Astrophysics Data System (ADS)

    Zeng, Y. K.; Zhou, X. L.; Zeng, L.; Yan, X. H.; Zhao, T. S.

    2016-09-01

    The catalyst for the negative electrode of iron-chromium redox flow batteries (ICRFBs) is commonly prepared by adding a small amount of Bi3+ ions in the electrolyte and synchronously electrodepositing metallic particles onto the electrode surface at the beginning of charge process. Achieving a uniform catalyst distribution in the porous electrode, which is closely related to the flow field design, is critically important to improve the ICRFB performance. In this work, the effects of flow field designs on catalyst electrodeposition and battery performance are investigated. It is found that compared to the serpentine flow field (SFF) design, the interdigitated flow field (IFF) forces the electrolyte through the porous electrode between the neighboring channels and enhances species transport during the processes of both the catalyst electrodeposition and iron/chromium redox reactions, thus enabling a more uniform catalyst distribution and higher mass transport limitation. It is further demonstrated that the energy efficiency of the ICRFB with the IFF reaches 80.7% at a high current density (320 mA cm-2), which is 8.2% higher than that of the ICRFB with the SFF. With such a high performance and intrinsically low-cost active materials, the ICRFB with the IFF offers a great promise for large-scale energy storage.

  2. Solid freeform-fabricated scaffolds designed to carry multicellular mesenchymal stem cell spheroids for cartilage regeneration.

    PubMed

    Huang, G S; Tseng, C S; Linju Yen, B; Dai, L G; Hsieh, P S; Hsu, S-h

    2013-10-13

    Three-dimensional (3D) cellular spheroids have recently emerged as a new trend to replace suspended single cells in modern cell-based therapies because of their greater regeneration capacities in vitro. They may lose the 3D structure during a change of microenvironment, which poses challenges to their translation in vivo. Besides, the conventional microporous scaffolds may have difficulty in accommodating these relatively large spheroids. Here we revealed a novel design of microenvironment for delivering and sustaining the 3D spheroids. Biodegradable scaffolds with macroporosity to accommodate mesenchymal stem cell (MSC) spheroids were made by solid freeform fabrication (SFF) from the solution of poly(D,L-lactide-co-glycolide). Their internal surface was modified with chitosan following air plasma treatment in order to preserve the morphology of the spheroids. It was demonstrated that human MSC spheroids loaded in SFF scaffolds produced a significantly larger amount of cartilage-associated extracellular matrix in vitro and in NOD/SCID mice compared to single cells in the same scaffolds. Implantation of MSC spheroid-loaded scaffolds into the chondral defects of rabbit knees showed superior cartilage regeneration. This study establishes new perspectives in designing the spheroid-sustaining microenvironment within a tissue engineering scaffold for in vivo applications.

  3. Improving the interfacial and mechanical properties of short glass fiber/epoxy composites by coating the glass fibers with cellulose nanocrystals

    Treesearch

    A. Asadi; M. Miller; Robert Moon; K. Kalaitzidou

    2016-01-01

    In this study, the interfacial and mechanical properties of cellulose nanocrystals (CNC) coated glass fiber/epoxy composites were investigated as a function of the CNC content on the surface of glass fibers (GF). Chopped GF rovings were coated with CNC by immersing the GF in CNC (0–5 wt%) aqueous suspensions. Single fiber fragmentation (SFF) tests showed that the...

  4. Respiratory carbon use and carbon storage in mid-rotation loblolly pine (Pinus taeda L.) plantations: the effect of site resources on the stand carbon balance

    Treesearch

    Chris A. Maier; Timothy J. Albaugh; H. Lee Allen; Phillip M. Dougherty

    2004-01-01

    We used estimates of autotrophic respiration (RA), net primary productivity (NPP) and soil CO2 evolution (Sff), to develop component carbon budgets for 12-year-old loblolly pine plantations during the fifth year of a fertilization and irrigation experiment. Annual carbon use in RA was 7.5, 9.0, 15.0, and 15.1 Mg C ha

  5. Characterization techniques to predict mechanical behaviour of green ceramic bodies fabricated by ceramic microstereolithography

    NASA Astrophysics Data System (ADS)

    Adake, Chandrashekhar V.; Bhargava, Parag; Gandhi, Prasanna

    2018-02-01

    Ceramic microstereolithography (CMSL) has emerged as solid free form (SFF) fabrication technology in which complex ceramic parts are fabricated from ceramic suspensions which are formulated by dispersing ceramic particles in UV curable resins. Ceramic parts are fabricated by exposing ceramic suspension to computer controlled UV light which polymerizes resin to polymer and this polymer forms rigid network around ceramic particles. A 3-dimensional part is created by piling cured layers one over the other. These ceramic parts are used to build microelectromechanical (MEMS) devices after thermal treatment. In many cases green ceramic parts can be directly utilized to build MEMS devices. Hence characterization of these parts is essential in terms of their mechanical behaviour prior to their use in MEMS devices. Mechanical behaviour of these green ceramic parts depends on cross link density which in turn depends on chemical structure of monomer, concentrations of photoinitiator and UV energy dose. Mechanical behaviour can be determined with the aid of nanoindentation. And extent of crosslinking can be verified with the aid of DSC. FTIR characterization is used to analyse (-C=C-) double bond conversion. This paper explains characterization tools to predict the mechanical behaviour of green ceramic bodies fabricated in CMSL

  6. Solid Freeform Fabrication Proceedings (9th) Held in Austin, Texas on August 10-12 1998

    DTIC Science & Technology

    1998-08-01

    both in-plane and out-of-plane, alter the path length of the light reflected from the region, immediately creating a pattern of optical interference ...fringes on the hologram. The interference fringe pattern can then be analyzed to determine the residual stresses that existed prior to the...of the final shape for each surface. In additive/subtractive SFF, geometry simplification due to decomposition avoids most of the tool interference

  7. Demonstration of fully enabled data center subsystem with embedded optical interconnect

    NASA Astrophysics Data System (ADS)

    Pitwon, Richard; Worrall, Alex; Stevens, Paul; Miller, Allen; Wang, Kai; Schmidtke, Katharine

    2014-03-01

    The evolution of data storage communication protocols and corresponding in-system bandwidth densities is set to impose prohibitive cost and performance constraints on future data storage system designs, fuelling proposals for hybrid electronic and optical architectures in data centers. The migration of optical interconnect into the system enclosure itself can substantially mitigate the communications bottlenecks resulting from both the increase in data rate and internal interconnect link lengths. In order to assess the viability of embedding optical links within prevailing data storage architectures, we present the design and assembly of a fully operational data storage array platform, in which all internal high speed links have been implemented optically. This required the deployment of mid-board optical transceivers, an electro-optical midplane and proprietary pluggable optical connectors for storage devices. We present the design of a high density optical layout to accommodate the midplane interconnect requirements of a data storage enclosure with support for 24 Small Form Factor (SFF) solid state or rotating disk drives and the design of a proprietary optical connector and interface cards, enabling standard drives to be plugged into an electro-optical midplane. Crucially, we have also modified the platform to accommodate longer optical interconnect lengths up to 50 meters in order to investigate future datacenter architectures based on disaggregation of modular subsystems. The optically enabled data storage system has been fully validated for both 6 Gb/s and 12 Gb/s SAS data traffic conveyed along internal optical links.

  8. A Methodology for Analyzing the Aptitude Content of the Non-Prior Service Youth and Enlisted Apprentice Populations

    DTIC Science & Technology

    1985-05-29

    POPULATIONS By William P. Hutzler Patricia A. Insley Betty Lou Bantor 29 May 1985 DISTRIBUTION LIMITED TO POD COMPONENTS ONLYr CTj SffM &f...10 SOURCE OF FUNDING NOS PROGRAM ELEMENT NO. PROJECT NO. TASK NO, WORK UNIT NO 12. PERSONAL AUTMOR(S) Hutzler. William P.; Inslev. Patricia...CONTENT OF THE NON-PRIOR SERVICE YOUTH AND ENLISTED APPRENTICE POPULATIONS By William P. Hutzler Patricia A. Insley Betty Lou Bantor 29 May 1985

  9. Viability of Bioprinted Cellular Constructs Using a Three Dispenser Cartesian Printer.

    PubMed

    Dennis, Sarah Grace; Trusk, Thomas; Richards, Dylan; Jia, Jia; Tan, Yu; Mei, Ying; Fann, Stephen; Markwald, Roger; Yost, Michael

    2015-09-22

    Tissue engineering has centralized its focus on the construction of replacements for non-functional or damaged tissue. The utilization of three-dimensional bioprinting in tissue engineering has generated new methods for the printing of cells and matrix to fabricate biomimetic tissue constructs. The solid freeform fabrication (SFF) method developed for three-dimensional bioprinting uses an additive manufacturing approach by depositing droplets of cells and hydrogels in a layer-by-layer fashion. Bioprinting fabrication is dependent on the specific placement of biological materials into three-dimensional architectures, and the printed constructs should closely mimic the complex organization of cells and extracellular matrices in native tissue. This paper highlights the use of the Palmetto Printer, a Cartesian bioprinter, as well as the process of producing spatially organized, viable constructs while simultaneously allowing control of environmental factors. This methodology utilizes computer-aided design and computer-aided manufacturing to produce these specific and complex geometries. Finally, this approach allows for the reproducible production of fabricated constructs optimized by controllable printing parameters.

  10. Treatment of temporal aliasing effects in the context of next generation satellite gravimetry missions

    NASA Astrophysics Data System (ADS)

    Daras, Ilias; Pail, Roland

    2017-09-01

    Temporal aliasing effects have a large impact on the gravity field accuracy of current gravimetry missions and are also expected to dominate the error budget of Next Generation Gravimetry Missions (NGGMs). This paper focuses on aspects concerning their treatment in the context of Low-Low Satellite-to-Satellite Tracking NGGMs. Closed-loop full-scale simulations are performed for a two-pair Bender-type Satellite Formation Flight (SFF), by taking into account error models of new generation instrument technology. The enhanced spatial sampling and error isotropy enable a further reduction of temporal aliasing errors from the processing perspective. A parameterization technique is adopted where the functional model is augmented by low-resolution gravity field solutions coestimated at short time intervals, while the remaining higher-resolution gravity field solution is estimated at a longer time interval. Fine-tuning the parameterization choices leads to significant reduction of the temporal aliasing effects. The investigations reveal that the parameterization technique in case of a Bender-type SFF can successfully mitigate aliasing effects caused by undersampling of high-frequency atmospheric and oceanic signals, since their most significant variations can be captured by daily coestimated solutions. This amounts to a "self-dealiasing" method that differs significantly from the classical dealiasing approach used nowadays for Gravity Recovery and Climate Experiment processing, enabling NGGMs to retrieve the complete spectrum of Earth's nontidal geophysical processes, including, for the first time, high-frequency atmospheric and oceanic variations.

  11. Au nanoparticles-ZnO composite nanotubes using natural silk fibroin fiber as template for electrochemical non-enzymatic sensing of hydrogen peroxide.

    PubMed

    Chen, Liangliang; Xu, Xiaolong; Cui, Feng; Qiu, Qianying; Chen, Xiaojun; Xu, Jinzhong

    2018-05-23

    A novel electrochemical sensor based on the composite of gold nanoparticles/zinc oxide nanotube (AuNPs/ZnO-NTs) was constructed and its application as hydrogen peroxide (H 2 O 2 ) non-enzymatic sensor was investigated. ZnO-NTs were prepared by a biomineralization strategy in which silk fibroin fiber (SFF) was used as template, and thus the ZnO-NTs inherited the advantages of SFF such as mechanical stability, flexible biomimetic morphology and biocompatibility. The AuNPs/ZnO-NTs was further prepared by the electrostatic absorption of AuNPs onto the surface of ZnO-NTs, and found to be capable to catalyze the reduction of H 2 O 2 . The working potential was 0.05 V, which was far higher than those in literatures, indicating the strong anti-interference ability in the real application. The catalytic current was linearly proportional in the concentration range of 1 μM-3.0 mM with a sensitivity of 1336.7 μA mM -1  cm -2 . The detection limit was estimated to be 0.1 μM (S/N = 3). Such a high sensitivity was attributed to the electrocatalytic property of ZnO and high electron transfer ability of AuNPs/ZnO-NTs structure. Moreover, the final detection results of H 2 O 2 in real samples showed the acceptable accuracy compared with the traditional potassium permanganate titration, exhibiting the prospect to be used as an applicable sensor in actual detections. Copyright © 2018 Elsevier Inc. All rights reserved.

  12. Muon reactivation in muon-catalyzed D-T fusion

    NASA Astrophysics Data System (ADS)

    Rafelski, H. E.; Müller, B.; Rafelski, J.; Trautmann, D.; Viollier, R. D.

    We comprehensively reanalyze and search for the density dependence of the effective muon alpha sticking fraction ωsff observed experimentally in muon catalyzed deuterium-tritium fusion. In our work particular emphasis has been put on the density dependent dense hydrogen stopping power. The main technical details and improvements in this work are: The (αμ) + 2s and 2p states are treated independently and are assigned individual reaction rates. The essential muonic excitation rates have been recalculated taking into account finite nuclear mass effects. The stopping power for a charged projectile in liquid heavy hydrogen is modified to account for dynamic screening effects and a density dependent effective ionization potential. It is shown that the medium dependent stopping power for the (αμ) + ion is the crucial factor controlling the density dependence of the effective sticking fraction. It is also pointed out that the muonic helium K α X-ray yield and the sticking fraction at high density can not be simultaneously brought into agreement with the experimental results without invoking novel mechanisms suppressing Stark mixing in the (Heμ) L-shell.

  13. Development of a Low-Cost Method for Whole-Spacecraft Isolation of Small Satellites

    DTIC Science & Technology

    2017-01-10

    c*m1* omega (i)^ 3 *j + c*m2* omega (i)^ 3 *j); % Sff(i)=(1+( omega (i)/w2/Q)^2)/((1-( omega (i)/w2)^2)^2+( omega (i)/... w2/Q)^2)*ABC_MPE_full(i)*abs(H2(i))^2...Paperwork Reduction Project (0704-0188) Washington DC 20503. 1. AGENCY USE ONLY (Leave Blank) 2. REPORT DATE December 2015 3 . REPORT TYPE AND DATES COVERED... 3 Incorporating Isolators on NPSCuL 41 3.1 Design Updates to NPSCuL . . . . . . . . . . . . . . . . . . . . 41 3.2 Test Set-Up and Configurations

  14. Multipoint dynamically reconfigure adaptive distributed fiber optic acoustic emission sensor (FAESense) system for condition based maintenance

    NASA Astrophysics Data System (ADS)

    Mendoza, Edgar; Prohaska, John; Kempen, Connie; Esterkin, Yan; Sun, Sunjian; Krishnaswamy, Sridhar

    2010-09-01

    This paper describes preliminary results obtained under a Navy SBIR contract by Redondo Optics Inc. (ROI), in collaboration with Northwestern University towards the development and demonstration of a next generation, stand-alone and fully integrated, dynamically reconfigurable, adaptive fiber optic acoustic emission sensor (FAESense™) system for the in-situ unattended detection and localization of shock events, impact damage, cracks, voids, and delaminations in new and aging critical infrastructures found in ships, submarines, aircraft, and in next generation weapon systems. ROI's FAESense™ system is based on the integration of proven state-of-the-art technologies: 1) distributed array of in-line fiber Bragg gratings (FBGs) sensors sensitive to strain, vibration, and acoustic emissions, 2) adaptive spectral demodulation of FBG sensor dynamic signals using two-wave mixing interferometry on photorefractive semiconductors, and 3) integration of all the sensor system passive and active optoelectronic components within a 0.5-cm x 1-cm photonic integrated circuit microchip. The adaptive TWM demodulation methodology allows the measurement of dynamic high frequnency acoustic emission events, while compensating for passive quasi-static strain and temperature drifts. It features a compact, low power, environmentally robust 1-inch x 1-inch x 4-inch small form factor (SFF) package with no moving parts. The FAESense™ interrogation system is microprocessor-controlled using high data rate signal processing electronics for the FBG sensors calibration, temperature compensation and the detection and analysis of acoustic emission signals. Its miniaturized package, low power operation, state-of-the-art data communications, and low cost makes it a very attractive solution for a large number of applications in naval and maritime industries, aerospace, civil structures, the oil and chemical industry, and for homeland security applications.

  15. A novel method for biomaterial scaffold internal architecture design to match bone elastic properties with desired porosity.

    PubMed

    Lin, Cheng Yu; Kikuchi, Noboru; Hollister, Scott J

    2004-05-01

    An often-proposed tissue engineering design hypothesis is that the scaffold should provide a biomimetic mechanical environment for initial function and appropriate remodeling of regenerating tissue while concurrently providing sufficient porosity for cell migration and cell/gene delivery. To provide a systematic study of this hypothesis, the ability to precisely design and manufacture biomaterial scaffolds is needed. Traditional methods for scaffold design and fabrication cannot provide the control over scaffold architecture design to achieve specified properties within fixed limits on porosity. The purpose of this paper was to develop a general design optimization scheme for 3D internal scaffold architecture to match desired elastic properties and porosity simultaneously, by introducing the homogenization-based topology optimization algorithm (also known as general layout optimization). With an initial target for bone tissue engineering, we demonstrate that the method can produce highly porous structures that match human trabecular bone anisotropic stiffness using accepted biomaterials. In addition, we show that anisotropic bone stiffness may be matched with scaffolds of widely different porosity. Finally, we also demonstrate that prototypes of the designed structures can be fabricated using solid free-form fabrication (SFF) techniques.

  16. Porogen-based solid freeform fabrication of polycaprolactone-calcium phosphate scaffolds for tissue engineering.

    PubMed

    Mondrinos, Mark J; Dembzynski, Robert; Lu, Lin; Byrapogu, Venkata K C; Wootton, David M; Lelkes, Peter I; Zhou, Jack

    2006-09-01

    Drop on demand printing (DDP) is a solid freeform fabrication (SFF) technique capable of generating microscale physical features required for tissue engineering scaffolds. Here, we report results toward the development of a reproducible manufacturing process for tissue engineering scaffolds based on injectable porogens fabricated by DDP. Thermoplastic porogens were designed using Pro/Engineer and fabricated with a commercially available DDP machine. Scaffolds composed of either pure polycaprolactone (PCL) or homogeneous composites of PCL and calcium phosphate (CaP, 10% or 20% w/w) were subsequently fabricated by injection molding of molten polymer-ceramic composites, followed by porogen dissolution with ethanol. Scaffold pore sizes, as small as 200 microm, were attainable using the indirect (porogen-based) method. Scaffold structure and porosity were analyzed by scanning electron microscopy (SEM) and microcomputed tomography, respectively. We characterized the compressive strength of 90:10 and 80:20 PCL-CaP composite materials (19.5+/-1.4 and 24.8+/-1.3 Mpa, respectively) according to ASTM standards, as well as pure PCL scaffolds (2.77+/-0.26 MPa) fabricated using our process. Human embryonic palatal mesenchymal (HEPM) cells attached and proliferated on all scaffolds, as evidenced by fluorescent nuclear staining with Hoechst 33258 and the Alamar Blue assay, with increased proliferation observed on 80:20 PCL-CaP scaffolds. SEM revealed multilayer assembly of HEPM cells on 80:20 PCL-CaP composite, but not pure PCL, scaffolds. In summary, we have developed an SFF-based injection molding process for the fabrication of PCL and PCL-CaP scaffolds that display in vitro cytocompatibility and suitable mechanical properties for hard tissue repair.

  17. mPUMA: a computational approach to microbiota analysis by de novo assembly of operational taxonomic units based on protein-coding barcode sequences.

    PubMed

    Links, Matthew G; Chaban, Bonnie; Hemmingsen, Sean M; Muirhead, Kevin; Hill, Janet E

    2013-08-15

    Formation of operational taxonomic units (OTU) is a common approach to data aggregation in microbial ecology studies based on amplification and sequencing of individual gene targets. The de novo assembly of OTU sequences has been recently demonstrated as an alternative to widely used clustering methods, providing robust information from experimental data alone, without any reliance on an external reference database. Here we introduce mPUMA (microbial Profiling Using Metagenomic Assembly, http://mpuma.sourceforge.net), a software package for identification and analysis of protein-coding barcode sequence data. It was developed originally for Cpn60 universal target sequences (also known as GroEL or Hsp60). Using an unattended process that is independent of external reference sequences, mPUMA forms OTUs by DNA sequence assembly and is capable of tracking OTU abundance. mPUMA processes microbial profiles both in terms of the direct DNA sequence as well as in the translated amino acid sequence for protein coding barcodes. By forming OTUs and calculating abundance through an assembly approach, mPUMA is capable of generating inputs for several popular microbiota analysis tools. Using SFF data from sequencing of a synthetic community of Cpn60 sequences derived from the human vaginal microbiome, we demonstrate that mPUMA can faithfully reconstruct all expected OTU sequences and produce compositional profiles consistent with actual community structure. mPUMA enables analysis of microbial communities while empowering the discovery of novel organisms through OTU assembly.

  18. Cycle time improvement for plastic injection moulding process by sub groove modification in conformal cooling channel

    NASA Astrophysics Data System (ADS)

    Kamarudin, K.; Wahab, M. S.; Batcha, M. F. M.; Shayfull, Z.; Raus, A. A.; Ahmed, Aqeel

    2017-09-01

    Mould designers have been struggling for the improvement of the cooling system performance, despite the fact that the cooling system complexity is physically limited by the fabrication capability of the conventional tooling methods. However, the growth of Solid Free Form Technology (SFF) allow the mould designer to develop more than just a regular conformal cooling channel. Numerous researchers demonstrate that conformal cooling channel was tremendously given significant result in the improvement of productivity and quality in the plastic injection moulding process. This paper presents the research work that applies the passive enhancement method in square shape cooling channel to enhance the efficiency of cooling performance by adding the sub groove to the cooling channel itself. Previous design that uses square shape cooling channel was improved by adding various numbers of sub groove to meet the best sub groove design that able reduced the cooling time. The effect of sub groove design on cooling time was investigated by Autodesk Modlflow Insight software. The simulation results showed that the various sub groove designs give different values to ejection time. The Design 7 showed the lowest value of ejection time with 24.3% increment. The addition of sub groove significantly increased a coolant velocity and a rate of heat transfer from molten plastic to coolant.

  19. The LDIFLARE and CCM methods demonstrate early nerve fibre abnormalities in untreated hypothyroidism: a prospective study.

    PubMed

    Sharma, Sanjeev; Tobin, Victoria; Vas, Prashant R J; Rayman, Gerry

    2018-05-31

    Recent studies using skin biopsy suggest presence of small fibre neuropathy in subclinical hypothyroidism. This study uses two novel non-invasive methods - the Laser Doppler imager (LDIFLARE) and Corneal confocal microscopy (CCM) - to assess small fibre function (SFF) and structure (SFS) respectively in newly diagnosed hypothyroidism (HT) before and after adequate treatment. Single-center, prospective, intervention-based cohort study. 20 patients with newly diagnosed HT- 15 primary and 5 post-radioiodine - along with 20 age-matched healthy controls (HC). Both HT and HC were assessed neurologically at diagnosis and baseline respectively. The HT group was reassessed after optimal replacement (defined as TSH:0.27-4.20mIU/L) with levothyroxine (LT4) while HC were reviewed at 1-year interval. Neurological assessment for small fibres was performed using the LDIFLARE for SFF and CCM for SFS while large fibres were studied by sural nerve conduction velocity (SNCV) and amplitude (SNAP). At baseline, compared to HC, both LDIFLARE (mean±SD) (6.74±1.20vs.8.90±1.75cm2; p=0.0002) and CCM-nerve fibre density (CNFD) (50.77±6.54vs.58.32±6.54no/mm2;p=0.002) were significantly reduced in HT whereas neither SNCV nor SNAP were different (p=>0.05). Following optimal LT4 treatment, both LDIFLARE (7.72±1.12vs.6.74±1.20 cm2; p=<0.0001) and CNFD (54.43±5.70vs.50.77±6.54no/mm2; p=0.02) improved significantly but remained significantly reduced compared to HC (p=0.008 and p=0.01 respectively) despite normalization of TSH. This study demonstrates that dysfunction of small fibres precedes large neural fibres in early hypothyroidism. This can be reversed by replacement therapy to achieve a biochemically euthyroid state but small fibres neural outcomes continued to be remain low when compared to HC.

  20. Selective laser sintering of calcium phosphate materials for orthopedic implants

    NASA Astrophysics Data System (ADS)

    Lee, Goonhee

    Two technologies, Solid Freeform Fabrication (SFF) and bioceramics are combined in this work to prepare bone replacement implants with complex geometry. SFF has emerged as a crucial technique for rapid prototyping in the last decade. Selective Laser Sintering (SLS) is one of the established SFF manufacturing processes that can build three-dimensional objects directly from computer models without part-specific tooling or human intervention. Meanwhile, there have been great efforts to develop implantable materials that can assist in regeneration of bone defects and injuries. However, little attention has been focused in shaping bones from these materials. The main thrust of this research was to develop a process that can combine those two separate efforts. The specific objective of this research is to develop a process that can construct bone replacement material of complex geometry from synthetic calcium phosphate materials by using the SLS process. The achievement of this goal can have a significant impact on the quality of health care in the sense that complete custom-fit bone and tooth structures suitable for implantation can be prepared within 24--48 hours of receipt of geometric information obtained either from patient Computed Tomographic (CT) data, from Computer Aided Design (CAD) software or from other imaging systems such as Magnetic Resonance Imaging (MRI) and Holographic Laser Range Imaging (HLRI). In this research, two different processes have been developed. First is the SLS fabrication of porous bone implants. In this effort, systematic procedures have been established and calcium phosphate implants were successfully fabricated from various sources of geometric information. These efforts include material selection and preparation, SLS process parameter optimization, and development of post-processing techniques within the 48-hour time frame. Post-processing allows accurate control of geometry and of the chemistry of calcium phosphate, as well as control of micro and macro pore structure, to maximize bone healing and provide sufficient mechanical strength. It also permits the complete removal of the polymeric binders that are resided in the SLS process. In collaboration with the University of Texas Health Science Center at San Antonio and BioMedical Enterprises, Inc., porous implants based on anatomical geometry have been successfully implanted in rabbits and dogs. These histologic animal studies reveal excellent biocompatibility and show its great potential for commercial custom-fit implant manufacture. The second research effort involves fabrication of fully dense bone for application in dental restoration and load-bearing orthopedic functions. Calcium phosphate glass melts, proven to be biocompatible in the first effort, were cast into carbon molds. Processes were developed for preparing the molds. These carbon molds of anatomic shape can be prepared from either Computer Numerical Control (CNC) milling of slab stock or SLS processing of thermoset-coated graphite powder. The CNC milling method provides accurate dimension of the molds in a short period of time, however, the capable geometries are limited; generally two pieces of molds are required for complex shapes. The SLS method provides very complex shape green molds. However, they need to go through pyrolysis of thermoset binder to provide the high temperature capability reached at calcium phosphate melt temperatures (1100°C) and noticeable shrinkage was observed during pyrolysis. The cast glass was annealed to develop polycrystalline calcium phosphate. This process also exhibits great potential.

  1. Solid freeform fabrication of biomaterials

    NASA Astrophysics Data System (ADS)

    Chu, Tien-Min Gabriel

    1999-12-01

    The biological performance of porous Hydroxyapatite (HA) is closely related to the pore architecture in the implants. The study on the effect of architecture to the biological performance of porous HA requires new manufacturing methods that can fabricate implants with controlled pores channels. In this thesis, four highly loaded HA and alumina suspensions were formulated and three different processes involving Solid Freeform Fabrication (SFF) were developed. An aqueous HA suspension in acrylamides was first formulated and the UV-curing properties were evaluated. With a medical grade HA powder, two non-aqueous HA suspensions were formulated: a 40 vol.% HA suspension in Hexanediol Diacrylate (HDDA) and a 40 vol.% HA suspension in 1:1 mix of Propoxylated Neopentyl Glycol Diacrylate (PNPGDA) and Isobomyl Acrylate (EBA). A 50 vol.% Alumina suspension in PNPGDA/IBA was also formulated. The effect of dispersant to the viscosity of the suspensions was characterized. In the Stereolithography (SL) method, the curing parameters of HA/HDDA and HA/PNPGDA/IBA were determined. Prototype HA implants with 1,700 mum internal channels were built directly on an SL Apparatus (SLA). The designed internal channel patterns were preserved after sintering. In the Ink-jet printing method, the high temperature flow behaviors of the suspensions were characterized. The effects of solids loading to the viscosity of the suspensions were modeled with Krieger-Dougherty equation. Leveling theory developed in paint industry was employed to analyze the self-leveling capability of the suspensions. In the indirect SL method, the thermal curing behavior of HA and alumina suspensions were characterized. The total cure time was measured and the curing kinetics was modeled. Negative molds for the implants were designed and built on SLA with epoxy resin. HA/PNPGDA/IBA was cast into the mold and cured in an oven. The binders and the epoxy mold were pyrolyzed and the green bodies sintered. Internal channels with sizes in the range of 420 to 968 gm with standard deviation less than 50 mum were successfully built. The formulation and characterization techniques developed in this thesis were useful for evaluating the suspensions for SFF process. The manufacturing process developed in this thesis have provided new methods for controlling the channel size in porous HA implants.

  2. Effects of evacuation assistant’s leading behavior on the evacuation efficiency: Information transmission approach

    NASA Astrophysics Data System (ADS)

    Wang, Xiao-Lu; Guo, Wei; Zheng, Xiao-Ping

    2015-07-01

    Evacuation assistants are expected to spread the escape route information and lead evacuees toward the exit as quickly as possible. Their leading behavior influences the evacuees’ movement directly, which is confirmed to be a decisive factor of the evacuation efficiency. The transmission process of escape information and its function on the evacuees’ movement are accurately presented by the proposed extended dynamic communication field model. For evacuation assistants and evacuees, their sensitivity parameter of static floor field (SFF), , and , are fully discussed. The simulation results indicate that the appropriate is associated with the maximum of evacuees. The optimal combinations of and were found to reach the highest evacuation efficiency. There also exists an optimal value for evacuation assistants’ information transmission radius. Project supported by the National Basic Research Program of China (Grant No. 2011CB706900), the National Natural Science Foundation of China (Grant Nos. 71225007 and 71203006), the National Key Technology Research and Development Program of the Ministry of Science and Technology of China (Grant No. 2012BAK13B06), the Humanities and Social Sciences Project of the Ministry of Education of China (Grant Nos. 10YJA630221 and 12YJCZH023), and the Beijing Philosophy and Social Sciences Planning Project of the Twelfth Five-Year Plan, China (Grant Nos. 12JGC090 and 12JGC098).

  3. Solid Freeform Fabrication of Composite-Material Objects

    NASA Technical Reports Server (NTRS)

    Wang, C. Jeff; Yang, Jason; Jang, Bor Z.

    2005-01-01

    Composite solid freeform fabrication (C-SFF) or composite layer manufacturing (CLM) is an automated process in which an advanced composite material (a matrix reinforced with continuous fibers) is formed into a freestanding, possibly complex, three-dimensional object. In CLM, there is no need for molds, dies, or other expensive tooling, and there is usually no need for machining to ensure that the object is formed to the desired net size and shape. CLM is a variant of extrusion-type rapid prototyping, in which a model or prototype of a solid object is built up by controlled extrusion of a polymeric or other material through an orifice that is translated to form patterned layers. The second layer is deposited on top of the first layer, the third layer is deposited on top of the second layer, and so forth, until the stack of layers reaches the desired final thickness and shape. The elements of CLM include (1) preparing a matrix resin in a form in which it will solidify subsequently, (2) mixing the fibers and matrix material to form a continuous pre-impregnated tow (also called "towpreg"), and (3) dispensing the pre-impregnated tow from a nozzle onto a base while moving the nozzle to form the dispensed material into a patterned layer of controlled thickness. When the material deposited into a given layer has solidified, the material for the next layer is deposited and patterned similarly, and so forth, until the desired overall object has been built up as a stack of patterned layers. Preferably, the deposition apparatus is controlled by a computer-aided design (CAD) system. The basic CLM concept can be adapted to the fabrication of parts from a variety of matrix materials. It is conceivable that a CLM apparatus could be placed at a remote location on Earth or in outer space where (1) spare parts are expected to be needed but (2) it would be uneconomical or impractical to store a full inventory of spare parts. A wide variety of towpregs could be prepared and stored on spools until needed. Long-shelf-life towpreg materials suitable for such use could include thermoplastic-coated carbon fibers and metal-coated SiC fibers. When a spare part was needed, the part could be fabricated by CLM under control by a CAD data file; thus, the part could be built automatically, at the scene, within hours or minutes.

  4. Mathematical modelling of scanner-specific bowtie filters for Monte Carlo CT dosimetry

    NASA Astrophysics Data System (ADS)

    Kramer, R.; Cassola, V. F.; Andrade, M. E. A.; de Araújo, M. W. C.; Brenner, D. J.; Khoury, H. J.

    2017-02-01

    The purpose of bowtie filters in CT scanners is to homogenize the x-ray intensity measured by the detectors in order to improve the image quality and at the same time to reduce the dose to the patient because of the preferential filtering near the periphery of the fan beam. For CT dosimetry, especially for Monte Carlo calculations of organ and tissue absorbed doses to patients, it is important to take the effect of bowtie filters into account. However, material composition and dimensions of these filters are proprietary. Consequently, a method for bowtie filter simulation independent of access to proprietary data and/or to a specific scanner would be of interest to many researchers involved in CT dosimetry. This study presents such a method based on the weighted computer tomography dose index, CTDIw, defined in two cylindrical PMMA phantoms of 16 cm and 32 cm diameter. With an EGSnrc-based Monte Carlo (MC) code, ratios CTDIw/CTDI100,a were calculated for a specific CT scanner using PMMA bowtie filter models based on sigmoid Boltzmann functions combined with a scanner filter factor (SFF) which is modified during calculations until the calculated MC CTDIw/CTDI100,a matches ratios CTDIw/CTDI100,a, determined by measurements or found in publications for that specific scanner. Once the scanner-specific value for an SFF has been found, the bowtie filter algorithm can be used in any MC code to perform CT dosimetry for that specific scanner. The bowtie filter model proposed here was validated for CTDIw/CTDI100,a considering 11 different CT scanners and for CTDI100,c, CTDI100,p and their ratio considering 4 different CT scanners. Additionally, comparisons were made for lateral dose profiles free in air and using computational anthropomorphic phantoms. CTDIw/CTDI100,a determined with this new method agreed on average within 0.89% (max. 3.4%) and 1.64% (max. 4.5%) with corresponding data published by CTDosimetry (www.impactscan.org) for the CTDI HEAD and BODY phantoms, respectively. Comparison with results calculated using proprietary data for the PHILIPS Brilliance 64 scanner showed agreement on average within 2.5% (max. 5.8%) and with data measured for that scanner within 2.1% (max. 3.7%). Ratios of CTDI100,c/CTDI100, p for this study and corresponding data published by CTDosimetry (www.impactscan.org) agree on average within about 11% (max. 28.6%). Lateral dose profiles calculated with the proposed bowtie filter and with proprietary data agreed within 2% (max. 5.9%), and both calculated data agreed within 5.4% (max. 11.2%) with measured results. Application of the proposed bowtie filter and of the exactly modelled filter to human phantom Monte Carlo calculations show agreement on the average within less than 5% (max. 7.9%) for organ and tissue absorbed doses.

  5. Freedom is an international partnership. [foreign contributions to NASA Space Station project

    NASA Technical Reports Server (NTRS)

    Kohrs, Richard H.

    1990-01-01

    The NASA Space Station Freedom (SSF) project initiated in 1984 is a collaborative one among the U.S., Japan, Canada, and the 10 nations participating in ESA. The SSF partners have over the last six years defined user requirements, decided on the hardware to be manufactured, and constructed a framework for long-term cooperation. SSF will be composed of user elements furnished by the foreign partners and a U.S.-supplied infrastructure encompassing the truss assembly, electrical power system, and crew living quarters. The U.S. will also furnish a lab and a polar-orbit platform; ESA, a second lab and the coorbiting Free-Flying Laboratory, as well as a second polar platform. Japan's Japanese Experiment Module shall include an Exposed Facility and an Experimental Logistics module. Canada will contribute the Mobile Servicing System robotic assembler/maintainer for the whole of SFF.

  6. Durability of filament-wound composite flywheel rotors

    NASA Astrophysics Data System (ADS)

    Koyanagi, Jun

    2012-02-01

    This paper predicts the durability of two types of flywheels, one assumes to fail in the radial direction and the other assumes to fail in the circumferential direction. The flywheel failing in the radial direction is a conventional filament-wound composite flywheel and the one failing in the circumferential direction is a tailor-made type. The durability of the former is predicted by Micromechanics of Failure (MMF) (Ha et al. in J. Compos. Mater. 42:1873-1875, 2008), employing time-dependent matrix strength, and that of the latter is predicted by Simultaneous Fiber Failure (SFF) (Koyanagi et al. in J. Compos. Mater. 43:1901-1914, 2009), employing identical time-dependent matrix strength. The predicted durability of the latter is much greater than that of the former, depending on the interface strength. This study suggests that a relatively weak interface is necessary for high-durability composite flywheel fabrication.

  7. Calibrating cellular automaton models for pedestrians walking through corners

    NASA Astrophysics Data System (ADS)

    Dias, Charitha; Lovreglio, Ruggiero

    2018-05-01

    Cellular Automata (CA) based pedestrian simulation models have gained remarkable popularity as they are simpler and easier to implement compared to other microscopic modeling approaches. However, incorporating traditional floor field representations in CA models to simulate pedestrian corner navigation behavior could result in unrealistic behaviors. Even though several previous studies have attempted to enhance CA models to realistically simulate pedestrian maneuvers around bends, such modifications have not been calibrated or validated against empirical data. In this study, two static floor field (SFF) representations, namely 'discrete representation' and 'continuous representation', are calibrated for CA-models to represent pedestrians' walking behavior around 90° bends. Trajectory data collected through a controlled experiment are used to calibrate these model representations. Calibration results indicate that although both floor field representations can represent pedestrians' corner navigation behavior, the 'continuous' representation fits the data better. Output of this study could be beneficial for enhancing the reliability of existing CA-based models by representing pedestrians' corner navigation behaviors more realistically.

  8. Compositional effects on the chemorheological properties and forming behavior of aqueous alumina-poly(vinyl alcohol) gelcasting suspensions

    NASA Astrophysics Data System (ADS)

    Morissette, Sherry L.

    A new gelcasting system based on aqueous, alumina-poly(vinyl alcohol) (PVA) suspensions cross-linked by an organotitanate coupling agent has been developed. Both the chemorheological properties and forming behavior of this system exhibited a strong compositional dependence. A sol- gel phase diagram was established, which yielded the critical titanium concentration [Ti] c required for gelation at a given PVA volume fraction, as well as the minimum PVA volume fraction ( fminPVA = 0.0245) and titanium PVA concentration ([Ti]min = 9.984 x 10--4 g Ti/ml) below which gelation was not observed irrespective of solution composition. The gelation time of suspensions of constant PVA volume fraction ( fsolnPVA ) decreased with increasing cross-linking agent concentration, PVA temperature, and solids volume fraction. The steady-state viscosity and elastic modulus of polymer solutions ( fsolnPVA = 0.05) of varying [Ti] were well described by the PVA percolation model, giving scaling exponents of 0.84 and 1.79, respectively. The steady-state elastic modulus of gel casting suspensions, which provides a measure of their handling strength in the as-gelled state, increased with increasing solids volume fraction. Gelcasting suspensions were used as feedstock for solid free-form fabrication (SFF) of ceramic components. The influence of processing conditions (e.g., tip diameter, mixing rate, table speed, etc.) and suspension rheology on deposition behavior was investigated. Continuous printablity was achieved for tip diameters ranging from dt = 0.254 -- 1.370 mm for all mixing rates (Rmix 5 -- 300 rpm) and suspension compositions (i.e., fAl2O3 = 0.45, φPVA = 0.275, [Ti] 0 -- 6.30 x 10--3 g Ti/ml) probed, where the minimum tip diameter for continuous printing was 0.203 mm. Printed lines were uniform with good edge definition. Line dimensions were independent of mixing rate for the given process conditions. The as-cast alumina volume fraction ( fAl2O3 ) depended on casting conditions and cross-linking agent concentration, where fAl2O3 decreased with increasing tip diameter and increased with increasing cross-linking agent concentration. Free-fomied Al2O3 components exhibited uniform particle packing and had minimal macro-defects (e.g., slumping or stair casing) and no detectable micro-defects (e.g., bubbles or cracking).

  9. The expected results method for data verification

    NASA Astrophysics Data System (ADS)

    Monday, Paul

    2016-05-01

    The credibility of United States Army analytical experiments using distributed simulation depends on the quality of the simulation, the pedigree of the input data, and the appropriateness of the simulation system to the problem. The second of these factors is best met by using classified performance data from the Army Materiel Systems Analysis Activity (AMSAA) for essential battlefield behaviors, like sensors, weapon fire, and damage assessment. Until recently, using classified data has been a time-consuming and expensive endeavor: it requires significant technical expertise to load, and it is difficult to verify that it works correctly. Fortunately, new capabilities, tools, and processes are available that greatly reduce these costs. This paper will discuss these developments, a new method to verify that all of the components are configured and operate properly, and the application to recent Army Capabilities Integration Center (ARCIC) experiments. Recent developments have focused improving the process to load the data. OneSAF has redesigned their input data file formats and structures so that they correspond exactly with the Standard File Format (SFF) defined by AMSAA, ARCIC developed a library of supporting configurations that correlate directly to the AMSAA nomenclature, and the Entity Validation Tool was designed to quickly execute the essential models with a test-jig approach to identify problems with the loaded data. The missing part of the process is provided by the new Expected Results Method. Instead of the usual subjective assessment of quality, e.g., "It looks about right to me", this new approach compares the performance of a combat model with authoritative expectations to quickly verify that the model, data, and simulation are all working correctly. Integrated together, these developments now make it possible to use AMSAA classified performance data with minimal time and maximum assurance that the experiment's analytical results will be of the highest quality possible.

  10. Emulsion Inks for 3D Printing of High Porosity Materials.

    PubMed

    Sears, Nicholas A; Dhavalikar, Prachi S; Cosgriff-Hernandez, Elizabeth M

    2016-08-01

    Photocurable emulsion inks for use with solid freeform fabrication (SFF) to generate constructs with hierarchical porosity are presented. A high internal phase emulsion (HIPE) templating technique was utilized to prepare water-in-oil emulsions from a hydrophobic photopolymer, surfactant, and water. These HIPEs displayed strong shear thinning behavior that permitted layer-by-layer deposition into complex shapes and adequately high viscosity at low shear for shape retention after extrusion. Each layer was actively polymerized with an ultraviolet cure-on-dispense (CoD) technique and compositions with sufficient viscosity were able to produce tall, complex scaffolds with an internal lattice structure and microscale porosity. Evaluation of the rheological and cure properties indicated that the viscosity and cure rate both played an important role in print fidelity. These 3D printed polyHIPE constructs benefit from the tunable pore structure of emulsion templated material and the designed architecture of 3D printing. As such, these emulsion inks can be used to create ultra high porosity constructs with complex geometries and internal lattice structures not possible with traditional manufacturing techniques. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  11. Algal sludge from Taihu Lake can be utilized to create novel PGPR-containing bio-organic fertilizers.

    PubMed

    Zhang, Miao; Li, Rong; Cao, Liangliang; Shi, Juanjuan; Liu, Hongjun; Huang, Yan; Shen, Qirong

    2014-01-01

    Large amounts of refloated algal sludge from Taihu Lake result in secondary environmental pollution due to annual refloatation. This study investigated the possibility to produce bio-organic fertilizer (BIO) using algal sludge as a solid-state fermentation (SSF) medium. Results showed that addition of algal sludge contributed to efficient SFF by a plant growth-promoting rhizobacteria (PGPR) strain SQR9 and improved the nutrient contents in the novel BIO. The optimum water content and initial inoculation size were 45% and 5%, respectively. After 6 days of SSF, the biomass of strain SQR9 was increased to a cell density of more than 5 × 10(7) CFU g(-1). Microcystins were rapidly degraded, and a high germination index value was observed. Plant growth experiments showed that the produced BIO efficiently promoted plant growth. Additional testing showed that the novel SSF process was also suitable for other PGPR strains. This study provides a novel way of high-value utilization of algal sludge from Taihu Lake by producing low-cost but high-quality BIOs. Copyright © 2013 Elsevier Ltd. All rights reserved.

  12. The impact of materials technology and operational constraints on the economics of cruise speed selection

    NASA Technical Reports Server (NTRS)

    Clauss, J. S., Jr.; Bruckman, F. A.; Horning, D. L.; Johnston, R. H.; Werner, J. V.

    1981-01-01

    Six material concepts at Mach 2.0 and three material concepts at Mach 2.55 were proposed. The resulting evaluations, based on projected development, production, and operating costs, indicate that aircraft designs with advanced composites as the primary material ingredient have the lowest fare premiums at both Mach 2.0 and 2.55. Designs having advanced metallics as the primary material ingredient are not economical. Advanced titanium, employing advanced manufacturing methods such as SFF/DB, requires a fare premium of about 30 percent at both Mach 2.0 and 2.55. Advanced aluminum, usable only at the lower Mach number, requires a fare premium of 20 percent. Cruise speeds in the Mach 2.0-2.3 regime are preferred because of the better economics and because of the availability of two material concepts to reduce program risk - advanced composites and advanced aluminums. This cruise speed regime also avoids the increase in risk associated with the more complex inlets and airframe systems and higher temperature composite matrices required at the higher Mach numbers typified by Mach 2.55.

  13. A three-dimensional hierarchical collagen scaffold fabricated by a combined solid freeform fabrication (SFF) and electrospinning process to enhance mesenchymal stem cell (MSC) proliferation

    NASA Astrophysics Data System (ADS)

    Ahn, SeungHyun; Koh, Young Ho; Kim, GeunHyung

    2010-06-01

    Collagen has the advantage of being very similar to macromolecular substances that can be recognized and metabolized in the biological environment. Although the natural material has superior property for this purpose, its use to fabricate reproducible and pore-structure-controlled 3D structures, which are designed to allow the entry of sufficient cells and the easy diffusion of nutrients, has been limited due to its low processability. Here, we propose a hybrid technology that combines a cryogenic plotting system with an electrospinning process. Using this technique, an easily pore-size-controllable hierarchical 3D scaffold consisting of micro-sized highly porous collagen strands and micro/nano-sized collagen fibers was fabricated. The pore structure of the collagen scaffold was controlled by the collagen micro/nanofibers, which were layered in the scaffold. The hierarchical scaffolds were characterized with respect to initial cell attachment and proliferation of bone marrow-derived mesenchymal stem cells within the scaffolds. The hierarchical scaffold exhibited incredibly enhanced initial cell attachment and cell compactness between pores of the plotted scaffold relative to the normally designed 3D collagen scaffold.

  14. Voice similarity in identical twins.

    PubMed

    Van Gysel, W D; Vercammen, J; Debruyne, F

    2001-01-01

    If people are asked to discriminate visually the two individuals of a monozygotic twin (MT), they mostly get into trouble. Does this problem also exist when listening to twin voices? Twenty female and 10 male MT voices were randomly assembled with one "strange" voice to get voice trios. The listeners (10 female students in Speech and Language Pathology) were asked to label the twins (voices 1-2, 1-3 or 2-3) in two conditions: two standard sentences read aloud and a 2.5-second midsection of a sustained /a/. The proportion correctly labelled twins was for female voices 82% and 63% and for male voices 74% and 52% for the sentences and the sustained /a/ respectively, both being significantly greater than chance (33%). The acoustic analysis revealed a high intra-twin correlation for the speaking fundamental frequency (SFF) of the sentences and the fundamental frequency (F0) of the sustained /a/. So the voice pitch could have been a useful characteristic in the perceptual identification of the twins. We conclude that there is a greater perceptual resemblance between the voices of identical twins than between voices without genetic relationship. The identification however is not perfect. The voice pitch possibly contributes to the correct twin identifications.

  15. Assessment of flushing methods for the removal of heavy chlorinated compounds DNAPL in an alluvial aquifer.

    PubMed

    Maire, Julien; Joubert, Antoine; Kaifas, Delphine; Invernizzi, Thomas; Marduel, Julien; Colombano, Stéfan; Cazaux, David; Marion, Cédric; Klein, Pierre-Yves; Dumestre, Alain; Fatin-Rouge, Nicolas

    2018-01-15

    Immiscible mobilization and foam flushing were assessed as low surfactant consuming technologies, for the enhanced recovery of dense non-aqueous phase liquid (DNAPL) residual at a site contaminated by heavy chlorinated compounds. Preliminary experiments in well-controlled conditions demonstrated the phenomena involved in these remediation technologies and their limitations. Furthermore, we characterized the technologies according to by their surfactant consumption (per kg of DNAPL recovered) and the final DNAPL saturation reached. Surfactant foam flushing (SFF) produced lower DNAPL saturation than immiscible mobilization, thanks to its higher viscosity. However, its efficiency is strongly correlated to the pressure gradient (▽P) used during injection, and that is limited by risks of soil fracturing. The two technologies were tested in field cells (10m×10m×10m) delimited by cement/bentonite walls anchored in the clayey substratum. The deepest soil layer was the most contaminated. It was composed of silt-sandy soil and had an average hydraulic conductivity of 10 -4 ms -1 . Field results show that we should now model flushing fluid propagation to design efficient set-ups for recovering the displaced DNAPL. Copyright © 2017 Elsevier B.V. All rights reserved.

  16. [Effects of long term mental arithmetic on physiological parameters, subjective indices and task performances].

    PubMed

    Yamada, Shimpei; Miyake, Shinji

    2007-03-01

    This study examined the effects of long term mental arithmetic on physiological parameters, subjective indices and task performances to investigate the psychophysiological changes induced by mental tasks. Fifteen male university students performed six successive trials of a ten-minute mental arithmetic task. They took a five-minute resting period before and after the tasks. CFF (Critical Flicker Fusion frequency) and subjective fatigue scores using a visual analog scale, POMS (Profiles of Mood States) and SFF (Subjective Feelings of Fatigue) were obtained after each task and resting period. The voices of participants who were instructed to speak five Japanese vowels ('a', 'i', 'u', 'e', 'o') were recorded after each block to investigate a chaotic property of vocal signals that is reported to be changed by fatigue. Subjective workload ratings were also obtained by the NASA-TLX (National Aeronautics and Space Administration-Task Load Index) after the task. Physiological signals of ECG (Electrocardiogram), PTG (Photoelectric Plethysmogram), SCL (Skin Conductance Level), TBV (Tissue Blood Volume) and Respiration were recorded for all experimental blocks. The number of answers, correct rates and average levels of task difficulty for each ten-minute task were used as task performance indices. In this experiment, the task performance did not decrease, whereas subjective fatigue increased. Activation of the sympathetic nervous system was suggested by physiological parameters.

  17. Kinetic modeling of simultaneous saccharification and fermentation of corn starch for ethanol production.

    PubMed

    Białas, Wojciech; Czerniak, Adrian; Szymanowska-Powałowska, Daria

    2014-01-01

    Fuel ethanol production, using a simultaneous saccharification and fermentation process (SSF) of native starch from corn flour, has been performed using Saccharomyces cerevisiae and a granular starch hydrolyzing enzyme. The quantitative effects of mash concentration, enzyme dose and pH were investigated with the use of a Box-Wilson central composite design protocol. Proceeding from results obtained in optimal fermentation conditions, a kinetics model relating the utilization rates of starch and glucose as well as the production rates of ethanol and biomass was tested. Moreover, scanning electron microscopy (SEM) was applied to investigate corn starch granule surface after the SFF process. A maximum ethanol concentration of 110.36 g/l was obtained for native corn starch using a mash concentration of 25%, which resulted in ethanol yield of 85.71%. The optimal conditions for the above yield were found with an enzyme dose of 2.05 ml/kg and pH of 5.0. These results indicate that by using a central composite design, it is possible to determine optimal values of the fermentation parameters for maximum ethanol production. The investigated kinetics model can be used to describe SSF process conducted with granular starch hydrolyzing enzymes. The SEM micrographs reveal randomly distributed holes on the surface of granules.

  18. NG6: Integrated next generation sequencing storage and processing environment.

    PubMed

    Mariette, Jérôme; Escudié, Frédéric; Allias, Nicolas; Salin, Gérald; Noirot, Céline; Thomas, Sylvain; Klopp, Christophe

    2012-09-09

    Next generation sequencing platforms are now well implanted in sequencing centres and some laboratories. Upcoming smaller scale machines such as the 454 junior from Roche or the MiSeq from Illumina will increase the number of laboratories hosting a sequencer. In such a context, it is important to provide these teams with an easily manageable environment to store and process the produced reads. We describe a user-friendly information system able to manage large sets of sequencing data. It includes, on one hand, a workflow environment already containing pipelines adapted to different input formats (sff, fasta, fastq and qseq), different sequencers (Roche 454, Illumina HiSeq) and various analyses (quality control, assembly, alignment, diversity studies,…) and, on the other hand, a secured web site giving access to the results. The connected user will be able to download raw and processed data and browse through the analysis result statistics. The provided workflows can easily be modified or extended and new ones can be added. Ergatis is used as a workflow building, running and monitoring system. The analyses can be run locally or in a cluster environment using Sun Grid Engine. NG6 is a complete information system designed to answer the needs of a sequencing platform. It provides a user-friendly interface to process, store and download high-throughput sequencing data.

  19. Characteristics of AVIRIS Band Measurements in Desert Agroecosystems in the Area of Blythe, California. 1; Studies of Cotton Spectra

    NASA Technical Reports Server (NTRS)

    Hanna, Safwat H. Shakir

    2001-01-01

    Airborne Visible/Infrared Imaging Spectrometer (AVIRIS) data from Blythe, California, were acquired in June 1997 to study agricultural spectra from different crops and to identify crops in other areas with similar environmental factors and similar spectral properties. The main objectives of this study are: (1) to compare the spectral and radiometric characteristics of AVIRIS data from agriculture crops with ground spectra measured by a FieldSpec ASD spectrometer; (2) to explore the use of AVIRIS spectral images for identifying agricultural crops; (3) to study the spectral expression of environmental factors on selected crops; and (4) to build a spectral library for the crops that were studied. A long-term goal is to extend the spectral library for different vegetation or crops in different stages of growth. To support our study, on July 18 and 19, 2000, we collected spectra using the FieldSpec spectrometer from selected fields with different crops in the Blythe area of California (longitude 114 deg 33.28 W and latitude 33 deg 25.42 N to longitude 1140 44.53 W and latitude 33 deg 39.77 N). These crops were cotton in different stages of growth, varieties of grass pure or mixed, Sudan grass, Bermuda grass, Teff grass, and alfalfa. Some of the fields were treated with different types of irrigation (i.e., wet to dry conditions). Additional parameters were studied such as the soil water content (WC), pH, and organic matter (OM). The results of this study showed that for crops known to be similar, there is a significant correlation between the spectra that were collected by AVIRIS in 1997 and spectra measured by the FieldSpec (registered) spectrometer in 2000. This correlation allowed development of a spectral library to be used in ENVI-IDL analysis software. This library was used successfully to identify different crops. Furthermore, using IDL algorithms of Spectral Angle Mapper classification (SAM), spectral feature fitting (SFF) and spectral binary encoding (SPE) showed that there is excellent agreement between the predicted and the actual crop type (i.e., the correlation is between 85-90% match). Further use of the AVIRIS images can be of a value to crop identification or crop yield for commercial use.

  20. Interactions of Hydrazine and Blowby Gases

    NASA Technical Reports Server (NTRS)

    Meagher, Nancy E.

    2003-01-01

    The interactions between hydrazine and blowby gases from pyrovalves was explored in this research project. Investigating the decomposition chemistry of hydrazine through detailed chemical kinetic modeling is a project started last summer while participating in the Summer Faculty Fellowship program. During the 1999-2000 academic year, the chemical kinetic mechanism for hydrazine decomposition developed while a SFF at NASA's White Sands Test Facility was further revised and validated against the limited experimental data in the literature. This mechanism was then used in assessing the effects of blowby gas species on hydrazine decomposition. The combustion products introduced into the fuel line by pyrovalve actuation consist primarily of hydrogen gas. Hydrogen is also a product of the decomposition of hydrazine. Additional gaseous chemical species are introduced into the fuel, as well as metals and metal salts that deposit onto the walls of the fuel line. The deposition process is undoubtedly very rapid, and exothermic. Therefore, the major focus of this summer's work was examining the effects of hydrogen presence on hydrazine decomposition, with some representative calculations including the remaining gaseous species found to exist in blowby gases. Since hydrogen is a product of hydrazine decomposition, all reactions necessary to evaluate its effect on hydrazine decomposition chemistry were in the original mechanism developed. However, the mechanism needed to be considerably expanded to include the reactions of the other gaseous blowby species with hydrazine, all the intermediate species formed in its decomposition, and each other. The expanded mechanism consists of 70 species interacting via a network of 452 reactions. Calculations with molecular hydrogen introduced into hydrazine gas in an inert bath gas indicate that H2 presence as an initial reactant in substantial amounts can dramatically impact the decomposition process for hydrazine. The other gaseous blowby species (CO, CO2, H2O, CH4, O2, and N2) were found to have little effect compared to the inclusion of hydrogen itself as an initial reagent. This result is undoubtedly due, in part, to the fact that the blowby gas used in these calculations consisted of 94.6% H2. A more rigorous examination of the behavior of the full detailed mechanism under a variety of conditions was not performed.

  1. Assessment of replicate bias in 454 pyrosequencing and a multi-purpose read-filtering tool.

    PubMed

    Jérôme, Mariette; Noirot, Céline; Klopp, Christophe

    2011-05-26

    Roche 454 pyrosequencing platform is often considered the most versatile of the Next Generation Sequencing technology platforms, permitting the sequencing of large genomes, the analysis of variations or the study of transcriptomes. A recent reported bias leads to the production of multiple reads for a unique DNA fragment in a random manner within a run. This bias has a direct impact on the quality of the measurement of the representation of the fragments using the reads. Other cleaning steps are usually performed on the reads before assembly or alignment. PyroCleaner is a software module intended to clean 454 pyrosequencing reads in order to ease the assembly process. This program is a free software and is distributed under the terms of the GNU General Public License as published by the Free Software Foundation. It implements several filters using criteria such as read duplication, length, complexity, base-pair quality and number of undetermined bases. It also permits to clean flowgram files (.sff) of paired-end sequences generating on one hand validated paired-ends file and the other hand single read file. Read cleaning has always been an important step in sequence analysis. The pyrocleaner python module is a Swiss knife dedicated to 454 reads cleaning. It includes commonly used filters as well as specialised ones such as duplicated read removal and paired-end read verification.

  2. Development of model hydroxyapatite bone scaffolds with multiscale porosity for potential load bearing applications

    NASA Astrophysics Data System (ADS)

    Dellinger, Jennifer Gwynne

    2005-11-01

    Model hydroxyapatite (HA) bone scaffolds consisting of a latticed pattern of rods were fabricated by a solid freeform fabrication (SFF) technique based on the robotic deposition of colloidal pastes. An optimal HA paste formulation for this method was developed. Local porosity, i.e. microporosity (1--30 mum) and sintering porosity (less than 1 mum), were produced by including polymer microsphere porogens in the HA pastes and by controlling the sintering of the scaffolds. Scaffolds with and without local porosity were evaluated with and without in vitro accelerated degradation. Percent weight loss of the scaffolds and calcium and phosphorus concentrations in solution increased with degradation time. After degradation, compressive strength and modulus decreased significantly for scaffolds with local porosity, but did not change significantly for scaffolds without local porosity. The compressive strength and modulus of scaffolds without local porosity were comparable to human cortical bone and were significantly greater than the scaffolds with local porosity. Micropores in HA disks caused surface pits that increased the surface roughness as compared to non-microporous HA disks. Mouse mesenchymal stem cells extended their cell processes into these microporous pits on HA disks in vitro. ALP expression was prolonged, cell attachment strength increased, and ECM production appeared greater on microporous HA disks compared to non-microporous HA disks and tissue culture treated polystyrene controls. Scaffolds with and without microporosity were implanted in goats bones. Microporous scaffolds with rhBMP-2 increased the percent of the scaffold filled with bone tissue compared to microporous scaffolds without rhBMP-2. Lamellar bone inside scaffolds was aligned near the rods junctions whereas lamellar bone was aligned in a more random configuration away from the rod junctions. Microporous scaffolds stained darkly with toluidine blue beneath areas of contact with new bone. This staining might indicate either extracellular matrix (ECM) in the rods or dye bound to the degrading scaffold. Although the presence of microporous topography alone did not influence bone healing in vivo, micropores were shown to provide tailorability of scaffold mechanical properties, provide a location for the storage and controlled release of a growth factor, and provide a location for bone integration inside the scaffold rods.

  3. De-Trending K2 Exoplanet Targets for High Spacecraft Motion

    NASA Astrophysics Data System (ADS)

    Saunders, Nicholas; Luger, Rodrigo; Barnes, Rory

    2018-01-01

    After the failure of two reaction wheels, the Kepler space telescope lost its fine pointing ability and entered a new phase of observation, K2. Targets observed by K2 have high motion relative to the detector and K2 light curves have higher noise than Kepler observations. Despite the increased noise, systematics removal pipelines such as K2SFF and EVEREST have enabled continued high-precision transiting planet science with the telescope, resulting in the detection of hundreds of new exoplanets. However, as the spacecraft begins to run out of fuel, sputtering will drive large and random variations in pointing that can prevent detection of exoplanets during the remaining 5 campaigns. In general, higher motion will spread the stellar point spread function (PSF) across more pixels during a campaign, which increases the number of degrees of freedom in the noise component and significantly reduces the de-trending power of traditional systematics removal methods. We use a model of the Kepler CCD combined with pixel-level information of a large number of stars across the detector to improve the performance of the EVEREST pipeline at high motion. We also consider the problem of increased crowding for static apertures in the high-motion regime and develop pixel response function (PRF)-fitting techniques to mitigate contamination and maximize the de-trending power. We assess the performance of our code by simulating sputtering events and assessing exoplanet detection efficiency with transit injection/recovery tests. We find that targets with roll amplitudes of up to 8 pixels, approximately 15 times K2 roll, can be de-trended within 2 to 3 factors of current K2 photometric precision for stars up to 14th magnitude. Achieved recovery precision allows detection of small planets around 11th and 12th magnitude stars. These methods can be applied to the light curves of K2 targets for existing and future campaigns to ensure that precision exoplanet science can still be performed despite increased motion. We further discuss how these methods can be applied to upcoming space telescope missions, such as the Transiting Exoplanet Survey Satellite (TESS), to improve future detection and characterization of exoplanet candidates.

  4. Speaking fundamental frequency and vowel formant frequencies: effects on perception of gender.

    PubMed

    Gelfer, Marylou Pausewang; Bennett, Quinn E

    2013-09-01

    The purpose of the present study was to investigate the contribution of vowel formant frequencies to gender identification in connected speech, the distinctiveness of vowel formants in males versus females, and how ambiguous speaking fundamental frequencies (SFFs) and vowel formants might affect perception of gender. Multivalent experimental. Speakers subjects (eight tall males, eight short females, and seven males and seven females of "middle" height) were recorded saying two carrier phrases to elicit the vowels /i/ and /α/ and a sentence. The gender/height groups were selected to (presumably) maximize formant differences between some groups (tall vs short) and minimize differences between others (middle height). Each subjects' samples were digitally altered to distinct SFFs (116, 145, 155, 165, and 207 Hz) to represent SFFs typical of average males, average females, and in an ambiguous range. Listeners judged the gender of each randomized altered speech sample. Results indicated that female speakers were perceived as female even with an SFF in the typical male range. For male speakers, gender perception was less accurate at SFFs of 165 Hz and higher. Although the ranges of vowel formants had considerable overlap between genders, significant differences in formant frequencies of males and females were seen. Vowel formants appeared to be important to perception of gender, especially for SFFs in the range of 145-165 Hz; however, formants may be a more salient cue in connected speech when compared with isolated vowels or syllables. Copyright © 2013 The Voice Foundation. Published by Mosby, Inc. All rights reserved.

  5. Acoustic markers to differentiate gender in prepubescent children's speaking and singing voice.

    PubMed

    Guzman, Marco; Muñoz, Daniel; Vivero, Martin; Marín, Natalia; Ramírez, Mirta; Rivera, María Trinidad; Vidal, Carla; Gerhard, Julia; González, Catalina

    2014-10-01

    Investigation sought to determine whether there is any acoustic variable to objectively differentiate gender in children with normal voices. A total of 30 children, 15 boys and 15 girls, with perceptually normal voices were examined. They were between 7 and 10 years old (mean: 8.1, SD: 0.7 years). Subjects were required to perform the following phonatory tasks: (1) to phonate sustained vowels [a:], [i:], [u:], (2) to read a phonetically balanced text, and (3) to sing a song. Acoustic analysis included long-term average spectrum (LTAS), fundamental frequency (F0), speaking fundamental frequency (SFF), equivalent continuous sound level (Leq), linear predictive code (LPC) to obtain formant frequencies, perturbation measures, harmonic to noise ratio (HNR), and Cepstral peak prominence (CPP). Auditory perceptual analysis was performed by four blinded judges to determine gender. No significant gender-related differences were found for most acoustic variables. Perceptual assessment showed good intra and inter rater reliability for gender. Cepstrum for [a:], alpha ratio in text, shimmer for [i:], F3 in [a:], and F3 in [i:], were the parameters that composed the multivariate logistic regression model to best differentiate male and female children's voices. Since perceptual assessment reliably detected gender, it is likely that other acoustic markers (not evaluated in the present study) are able to make clearer gender differences. For example, gender-specific patterns of intonation may be a more accurate feature for differentiating gender in children's voices. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  6. Universal behavior of the γ⁎γ→(π0,η,η′) transition form factors

    PubMed Central

    Melikhov, Dmitri; Stech, Berthold

    2012-01-01

    The photon transition form factors of π, η and η′ are discussed in view of recent measurements. It is shown that the exact axial anomaly sum rule allows a precise comparison of all three form factors at high-Q2 independent of the different structures and distribution amplitudes of the participating pseudoscalar mesons. We conclude: (i) The πγ form factor reported by Belle is in excellent agreement with the nonstrange I=0 component of the η and η′ form factors obtained from the BaBar measurements. (ii) Within errors, the πγ form factor from Belle is compatible with the asymptotic pQCD behavior, similar to the η and η′ form factors from BaBar. Still, the best fits to the data sets of πγ, ηγ, and η′γ form factors favor a universal small logarithmic rise Q2FPγ(Q2)∼log(Q2). PMID:23226917

  7. Analysis of nucleon electromagnetic form factors from light-front holographic QCD: The spacelike region

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sufian, Raza Sabbir; de Teramond, Guy F.; Brodsky, Stanley J.

    We present a comprehensive analysis of the space-like nucleon electromagnetic form factors and their flavor decomposition within the framework of light-front holographic QCD. We show that the inclusion of the higher Fock componentsmore » $$|{qqqq\\bar{q}}$$ has a significant effect on the spin-flip elastic Pauli form factor and almost zero effect on the spin-conserving Dirac form factor. We present light-front holographic QCD results for the proton and neutron form factors at any momentum transfer range, including asymptotic predictions, and show that our results agree with the available experimental data with high accuracy. In order to correctly describe the Pauli form factor we need an admixture of a five quark state of about 30$$\\%$$ in the proton and about 40$$\\%$$ in the neutron. We also extract the nucleon charge and magnetic radii and perform a flavor decomposition of the nucleon electromagnetic form factors. The free parameters needed to describe the experimental nucleon form factors are very few: two parameters for the probabilities of higher Fock states for the spin-flip form factor and a phenomenological parameter $r$, required to account for possible SU(6) spin-flavor symmetry breaking effects in the neutron, whereas the Pauli form factors are normalized to the experimental values of the anomalous magnetic moments. As a result, the covariant spin structure for the Dirac and Pauli nucleon form factors prescribed by AdS$$_5$$ semiclassical gravity incorporates the correct twist scaling behavior from hard scattering and also leads to vector dominance at low energy.« less

  8. Analysis of nucleon electromagnetic form factors from light-front holographic QCD: The spacelike region

    DOE PAGES

    Sufian, Raza Sabbir; de Teramond, Guy F.; Brodsky, Stanley J.; ...

    2017-01-10

    We present a comprehensive analysis of the space-like nucleon electromagnetic form factors and their flavor decomposition within the framework of light-front holographic QCD. We show that the inclusion of the higher Fock componentsmore » $$|{qqqq\\bar{q}}$$ has a significant effect on the spin-flip elastic Pauli form factor and almost zero effect on the spin-conserving Dirac form factor. We present light-front holographic QCD results for the proton and neutron form factors at any momentum transfer range, including asymptotic predictions, and show that our results agree with the available experimental data with high accuracy. In order to correctly describe the Pauli form factor we need an admixture of a five quark state of about 30$$\\%$$ in the proton and about 40$$\\%$$ in the neutron. We also extract the nucleon charge and magnetic radii and perform a flavor decomposition of the nucleon electromagnetic form factors. The free parameters needed to describe the experimental nucleon form factors are very few: two parameters for the probabilities of higher Fock states for the spin-flip form factor and a phenomenological parameter $r$, required to account for possible SU(6) spin-flavor symmetry breaking effects in the neutron, whereas the Pauli form factors are normalized to the experimental values of the anomalous magnetic moments. As a result, the covariant spin structure for the Dirac and Pauli nucleon form factors prescribed by AdS$$_5$$ semiclassical gravity incorporates the correct twist scaling behavior from hard scattering and also leads to vector dominance at low energy.« less

  9. Iso-vector form factors of the delta and nucleon in QCD sum rules

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ozpineci, A.

    Form factors are important non-perturbative properties of hadrons. They give information about the internal structure of the hadrons. In this work, iso-vector axial-vector and iso-vector tensor form factors of the nucleon and the iso-vector axial-vector {Delta}{yields}N transition form factor calculations in QCD Sum Rules are presented.

  10. Use of field reflectance data for crop mapping using airborne hyperspectral image

    NASA Astrophysics Data System (ADS)

    Nidamanuri, Rama Rao; Zbell, Bernd

    2011-09-01

    Recent developments in hyperspectral remote sensing technologies enable acquisition of image with high spectral resolution, which is typical to the laboratory or in situ reflectance measurements. There has been an increasing interest in the utilization of in situ reference reflectance spectra for rapid and repeated mapping of various surface features. Here we examined the prospect of classifying airborne hyperspectral image using field reflectance spectra as the training data for crop mapping. Canopy level field reflectance measurements of some important agricultural crops, i.e. alfalfa, winter barley, winter rape, winter rye, and winter wheat collected during four consecutive growing seasons are used for the classification of a HyMAP image acquired for a separate location by (1) mixture tuned matched filtering (MTMF), (2) spectral feature fitting (SFF), and (3) spectral angle mapper (SAM) methods. In order to answer a general research question "what is the prospect of using independent reference reflectance spectra for image classification", while focussing on the crop classification, the results indicate distinct aspects. On the one hand, field reflectance spectra of winter rape and alfalfa demonstrate excellent crop discrimination and spectral matching with the image across the growing seasons. On the other hand, significant spectral confusion detected among the winter barley, winter rye, and winter wheat rule out the possibility of existence of a meaningful spectral matching between field reflectance spectra and image. While supporting the current notion of "non-existence of characteristic reflectance spectral signatures for vegetation", results indicate that there exist some crops whose spectral signatures are similar to characteristic spectral signatures with possibility of using them in image classification.

  11. Developing the Scale for Quality of Life in Pediatric Oncology Patients Aged 13-18: Adolescent Form and Parent Form.

    PubMed

    Bektas, Murat; Akdeniz Kudubes, Aslı; Ugur, Ozlem; Vergin, Canan; Demirag, Bengü

    2016-06-01

    This study aimed to develop the Scale for Quality of Life in Pediatric Oncology Patients Aged 13-18: Adolescent Form and Parent Form. We used the child and parent information form, Visual Quality of Life Scale, and our own scale, the Scale for Quality of Life in Pediatric Oncology Patients Aged 13-18: Adolescent Form and Parent Form. We finalized the 35-item scale to determine the items, received opinions from 14 specialists on the scale, and pilot-tested the scale in 25 children and their parents. We used Pearson correlation analysis, Cronbach α coefficient, factor analysis and receiver operating characteristics analysis to analyze the data. The total Cronbach α of the parent form was .97, the total factor load was .60-.97 and the total variance was 80.4%. The cutoff point of the parent form was 85.50. The total Cronbach α of the adolescent form was .98, the total factor load was .62-.96, and the total variance explained was 83.4%. The cutoff point of the adolescent form was 75.50. As a result of the parent form factor analysis, we determined the Kaiser-Meyer-Olkin coefficient as .83, the Barlett test χ(2) as 12,615.92; the factor coefficients of all items of the parent form ranged from .63 to .98. The factor coefficients of all items of the adolescent form ranged from .34 to .99. As a result of the adolescent form factor analysis, we determined the KMO as .79, and the Barlett test χ(2) as 13,970.62. Conclusively, we found that the adolescent form and the parent form were valid and reliable in assessing the children's quality of life. Copyright © 2016. Published by Elsevier B.V.

  12. Calculation of the Nucleon Axial Form Factor Using Staggered Lattice QCD

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Meyer, Aaron S.; Hill, Richard J.; Kronfeld, Andreas S.

    The nucleon axial form factor is a dominant contribution to errors in neutrino oscillation studies. Lattice QCD calculations can help control theory errors by providing first-principles information on nucleon form factors. In these proceedings, we present preliminary results on a blinded calculation ofmore » $$g_A$$ and the axial form factor using HISQ staggered baryons with 2+1+1 flavors of sea quarks. Calculations are done using physical light quark masses and are absolutely normalized. We discuss fitting form factor data with the model-independent $z$ expansion parametrization.« less

  13. Electromagnetic structure of the proton within the CP-violation hypothesis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Krutov, A. F., E-mail: krutov@ssu.samara.ru; Kudinov, M. Yu., E-mail: kudinov@ssu.samara.ru

    2013-11-15

    The so-called non-Rosenbluth behavior of the proton electromagnetic form factors can be explained within the hypothesis of CP violation in electromagnetic processes involving composite systems of strongly interacting particles. It is shown that this hypothesis leads to the appearance of an additional, anapole, form factor of the proton. The proton electromagnetic form factors, including the anapole form factor, are estimated on the basis of experimental data on elastic electron-proton scattering.

  14. X-Ray Form Factor, Attenuation and Scattering Tables

    National Institute of Standards and Technology Data Gateway

    SRD 66 X-Ray Form Factor, Attenuation and Scattering Tables (Web, free access)   This database collects tables and graphs of the form factors, the photoabsorption cross section, and the total attenuation coefficient for any element (Z <= 92).

  15. Dispersive analysis of the pion transition form factor

    NASA Astrophysics Data System (ADS)

    Hoferichter, M.; Kubis, B.; Leupold, S.; Niecknig, F.; Schneider, S. P.

    2014-11-01

    We analyze the pion transition form factor using dispersion theory. We calculate the singly-virtual form factor in the time-like region based on data for the cross section, generalizing previous studies on decays and scattering, and verify our result by comparing to data. We perform the analytic continuation to the space-like region, predicting the poorly-constrained space-like transition form factor below , and extract the slope of the form factor at vanishing momentum transfer . We derive the dispersive formalism necessary for the extension of these results to the doubly-virtual case, as required for the pion-pole contribution to hadronic light-by-light scattering in the anomalous magnetic moment of the muon.

  16. Longitudinal vector form factors in weak decays of nuclei

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Šimkovic, F.; Department of Nuclear Physics and Biophysics, Comenius University, Mlynská dolina F1 SK–842 48 Bratislava; Kovalenko, S.

    2015-10-28

    The longitudinal form factors of the weak vector current of particles with spin J = 1/2 and isospin I = 1/2 are determined by the mass difference and the charge radii of members of the isotopic doublets. The most promising reactions to measure these form factors are the reactions with large momentum transfers involving the spin-1/2 isotopic doublets with a maximum mass splitting. Numerical estimates of longitudinal form factors are given for nucleons and eight nuclear spin-1/2 isotopic doublets.

  17. The pion form factor from first principles

    NASA Astrophysics Data System (ADS)

    van der Heide, J.

    2004-08-01

    We calculate the electromagnetic form factor of the pion in quenched lattice QCD. The non-perturbatively improved Sheikoleslami-Wohlert lattice action is used together with the O(a) improved current. We calculate form factor for pion masses down to mπ = 380 MeV. We compare the mean square radius for the pion extracted from our form factors to the value obtained from the `Bethe Salpeter amplitude'. Using (quenched) chiral perturbation theory, we extrapolate our results towards the physical pion mass.

  18. Electromagnetic {\\varvec{N}}^{\\varvec{*}} Transition Form Factors in the ANL-Osaka Dynamical Coupled-Channels Approach

    NASA Astrophysics Data System (ADS)

    Kamano, Hiroyuki

    2018-05-01

    We give an overview of our recent efforts to extract electromagnetic transition form factors for N^* and Δ^* baryon resonances through a global analysis of the single-pion electroproductions off the proton within the ANL-Osaka dynamical coupled-channels approach. Preliminary results for the extracted form factors associated with Δ(1232)3/2^+ and the Roper resonance are presented, with emphasis on the complex-valued nature of the transition form factors defined by poles.

  19. The scalar and electromagnetic form factors of the nucleon in dispersively improved Chiral EFT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Alarcon, Jose Manuel

    We present a method for calculating the nucleon form factors of G-parity-even operators. This method combines chiral effective field theory (χEFT) and dispersion theory. Through unitarity we factorize the imaginary part of the form factors into a perturbative part, calculable with χEFT, and a non-perturbative part, obtained through other methods. We consider the scalar and electromagnetic (EM) form factors of the nucleon. The results show an important improvement compared to standard chiral calculations, and can be used in analysis of the low-energy properties of the nucleon.

  20. 8 CFR 204.309 - Factors requiring denial of a Form I-800A or Form I-800.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Factors requiring denial of a Form I-800A or Form I-800. 204.309 Section 204.309 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS IMMIGRANT PETITIONS Intercountry Adoption of a Convention Adoptee § 204.309 Factors...

  1. Concurrent and Construct Validity of Three Counselor Social Influence Instruments.

    ERIC Educational Resources Information Center

    Wilson, F. Robert; Yager, Geoffrey G.

    1990-01-01

    Conducted factor analytic investigation of Counselor Rating Form, Counselor Rating Form-Short Form, and Counselor Effectiveness Rating Scale (CERS) using data from 160 undergraduate students. Analysis revealed two oblique factors (expertness and attractiveness-trustworthiness), whereas CERS produced single, global evaluative factor. Oblique…

  2. Emotional Intelligence and Nurse Recruitment: Rasch and confirmatory factor analysis of the trait emotional intelligence questionnaire short form.

    PubMed

    Snowden, Austyn; Watson, Roger; Stenhouse, Rosie; Hale, Claire

    2015-12-01

    To examine the construct validity of the Trait Emotional Intelligence Questionnaire Short form. Emotional intelligence involves the identification and regulation of our own emotions and the emotions of others. It is therefore a potentially useful construct in the investigation of recruitment and retention in nursing and many questionnaires have been constructed to measure it. Secondary analysis of existing dataset of responses to Trait Emotional Intelligence Questionnaire Short form using concurrent application of Rasch analysis and confirmatory factor analysis. First year undergraduate nursing and computing students completed Trait Emotional Intelligence Questionnaire-Short Form in September 2013. Responses were analysed by synthesising results of Rasch analysis and confirmatory factor analysis. Participants (N = 938) completed Trait Emotional Intelligence Questionnaire Short form. Rasch analysis showed the majority of the Trait Emotional Intelligence Questionnaire-Short Form items made a unique contribution to the latent trait of emotional intelligence. Five items did not fit the model and differential item functioning (gender) accounted for this misfit. Confirmatory factor analysis revealed a four-factor structure consisting of: self-confidence, empathy, uncertainty and social connection. All five misfitting items from the Rasch analysis belonged to the 'social connection' factor. The concurrent use of Rasch and factor analysis allowed for novel interpretation of Trait Emotional Intelligence Questionnaire Short form. Much of the response variation in Trait Emotional Intelligence Questionnaire Short form can be accounted for by the social connection factor. Implications for practice are discussed. © 2015 John Wiley & Sons Ltd.

  3. Nucleon electromagnetic form factors using lattice simulations at the physical point

    NASA Astrophysics Data System (ADS)

    Alexandrou, C.; Constantinou, M.; Hadjiyiannakou, K.; Jansen, K.; Kallidonis, Ch.; Koutsou, G.; Vaquero Aviles-Casco, A.

    2017-08-01

    We present results for the nucleon electromagnetic form factors using an ensemble of maximally twisted mass clover-improved fermions with pion mass of about 130 MeV. We use multiple sink-source separations and three analysis methods to probe ground-state dominance. We evaluate both the connected and disconnected contributions to the nucleon matrix elements. We find that the disconnected quark loop contributions to the isoscalar matrix elements are small, giving an upper bound of up to 2% of the connected and smaller than its statistical error. We present results for the isovector and isoscalar electric and magnetic Sachs form factors and the corresponding proton and neutron form factors. By fitting the momentum dependence of the form factors to a dipole form or to the z expansion, we extract the nucleon electric and magnetic radii, as well as the magnetic moment. We compare our results to experiment as well as to other recent lattice QCD calculations.

  4. Exploratory Bi-Factor Analysis: The Oblique Case

    ERIC Educational Resources Information Center

    Jennrich, Robert I.; Bentler, Peter M.

    2012-01-01

    Bi-factor analysis is a form of confirmatory factor analysis originally introduced by Holzinger and Swineford ("Psychometrika" 47:41-54, 1937). The bi-factor model has a general factor, a number of group factors, and an explicit bi-factor structure. Jennrich and Bentler ("Psychometrika" 76:537-549, 2011) introduced an exploratory form of bi-factor…

  5. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Safari, L., E-mail: laleh.safari@ist.ac.at; Department of Physics, University of Oulu, Box 3000, FI-90014 Oulu; Santos, J. P.

    Atomic form factors are widely used for the characterization of targets and specimens, from crystallography to biology. By using recent mathematical results, here we derive an analytical expression for the atomic form factor within the independent particle model constructed from nonrelativistic screened hydrogenic wave functions. The range of validity of this analytical expression is checked by comparing the analytically obtained form factors with the ones obtained within the Hartee-Fock method. As an example, we apply our analytical expression for the atomic form factor to evaluate the differential cross section for Rayleigh scattering off neutral atoms.

  6. Dispersive analysis of the pion transition form factor.

    PubMed

    Hoferichter, M; Kubis, B; Leupold, S; Niecknig, F; Schneider, S P

    We analyze the pion transition form factor using dispersion theory. We calculate the singly-virtual form factor in the time-like region based on data for the [Formula: see text] cross section, generalizing previous studies on [Formula: see text] decays and [Formula: see text] scattering, and verify our result by comparing to [Formula: see text] data. We perform the analytic continuation to the space-like region, predicting the poorly-constrained space-like transition form factor below [Formula: see text], and extract the slope of the form factor at vanishing momentum transfer [Formula: see text]. We derive the dispersive formalism necessary for the extension of these results to the doubly-virtual case, as required for the pion-pole contribution to hadronic light-by-light scattering in the anomalous magnetic moment of the muon.

  7. Hadronic Form Factors in Asymptotically Free Field Theories

    DOE R&D Accomplishments Database

    Gross, D. J.; Treiman, S. B.

    1974-01-01

    The breakdown of Bjorken scaling in asymptotically free gauge theories of the strong interactions is explored for its implications on the large q{sup 2} behavior of nucleon form factors. Duality arguments of Bloom and Gilman suggest a connection between the form factors and the threshold properties of the deep inelastic structure functions. The latter are addressed directly in an analysis of asymptotically free theories; and through the duality connection we are then led to statements about the form factors. For very large q{sup 2} the form factors are predicted to fall faster than any inverse power of q{sup 2}. For the more modest range of q{sup 2} reached in existing experiments the agreement with data is fairly good, though this may well be fortuitous. Extrapolations beyond this range are presented.

  8. $$B\\to Kl^+l^-$$ decay form factors from three-flavor lattice QCD

    DOE PAGES

    Bailey, Jon A.

    2016-01-27

    We compute the form factors for the B → Kl +l - semileptonic decay process in lattice QCD using gauge-field ensembles with 2+1 flavors of sea quark, generated by the MILC Collaboration. The ensembles span lattice spacings from 0.12 to 0.045 fm and have multiple sea-quark masses to help control the chiral extrapolation. The asqtad improved staggered action is used for the light valence and sea quarks, and the clover action with the Fermilab interpretation is used for the heavy b quark. We present results for the form factors f+(q 2), f 0(q 2), and f T(q 2), where q 2more » is the momentum transfer, together with a comprehensive examination of systematic errors. Lattice QCD determines the form factors for a limited range of q 2, and we use the model-independent z expansion to cover the whole kinematically allowed range. We present our final form-factor results as coefficients of the z expansion and the correlations between them, where the errors on the coefficients include statistical and all systematic uncertainties. Lastly, we use this complete description of the form factors to test QCD predictions of the form factors at high and low q 2.« less

  9. Overcoming diabetes-related stigma in Iran: A participatory action research.

    PubMed

    Doosti-Irani, Mehri; Abdoli, Samereh; Parvizy, Soroor; Fatemi, Naimeh Seyed

    2017-08-01

    The study aimed to overcome diabetes-related stigma in individuals living with type 1 Diabetes Mellitus (T1DM) in Iran. The study proposed that if individuals with T1DM and the community work together to develop and implement an anti-stigma program, diabetes-related stigma in individuals with T1DM can be reduced. This study was conducted as a participatory action research study based on Kemmis and McTaggert's (2000) Model to design and implement an anti-stigma program for T1DM. Participants were selected among individuals with T1DM, their family members, health care providers, and residents without diabetes in Isfahan, Iran. Data collection was conducted using interviews, focus groups, emails, and text messages. Content analysis was used to analyze the data to develop anti-stigma interventions. Interventions were prioritized based on the Suitability, Feasibility and Flexibility (SFF) Matrix. Anti-stigma interventions were implemented in different levels in Isfahan, Iran, from 2011 to 2014. The effect of the program was evaluated based on interviews, feedback, and focus groups at the individual level. However, interventions were implemented in different levels including community, organization, family, and individual. Participants with T1DM experienced significant empowerment during the project to overcome diabetes-related stigma. The three main themes indicating this feeling of empowerment are "from doubt to trust", "from shadow to light", and "from me to us". Participatory action research can be an effective way to reduce diabetes-related stigma in individuals living with T1DM. It integrates the voices of the marginalized group reducing stigma and discrimination against diabetes. Copyright © 2017. Published by Elsevier Inc.

  10. Perceptual and acoustic outcomes of voice therapy for male-to-female transgender individuals immediately after therapy and 15 months later.

    PubMed

    Gelfer, Marylou Pausewang; Tice, Ruthanne M

    2013-05-01

    The present study examined how effectively listeners' perceptions of gender could be changed from male to female for male-to-female (MTF) transgender (TG) clients based on the voice signal alone, immediately after voice therapy and at long-term follow-up. Short- and long-term changes in masculinity and femininity ratings and acoustic measures of speaking fundamental frequency (SFF) and vowel formant frequencies were also investigated. Prospective treatment study. Five MTF TG clients, five control female speakers, and five control male speakers provided a variety of speech samples for later analysis. The TG clients then underwent 8 weeks of voice therapy. Voice samples were collected immediately at the termination of therapy and again 15 months later. Two groups of listeners were recruited to evaluate gender and provide masculinity and femininity ratings. Perceptual results revealed that TG subjects were perceived as female 1.9% of the time in the pretest, 50.8% of the time in the immediate posttest, and 33.1% of the time in the long-term posttest. The TG speakers were also perceived as significantly less masculine and more feminine in the immediate posttest and the long-term posttest compared with the pre-test. Some acoustic measures showed significant differences between the pretest and the immediate posttest and long-term posttest. It appeared that 8 weeks of voice therapy could result in vocal changes in MTF TG individuals that persist at least partially for up to 15 months. However, some TG subjects were more successful with voice feminization than others. Copyright © 2013 The Voice Foundation. Published by Mosby, Inc. All rights reserved.

  11. Extraction of hydrothermal alterations from ASTER SWIR data from east Zanjan, northern Iran

    NASA Astrophysics Data System (ADS)

    Azizi, H.; Tarverdi, M. A.; Akbarpour, A.

    2010-07-01

    The use of satellite images for mineral exploration has been very successful in pointing out the presence of minerals such as smectite and kaolinite which are important in the identification of hydrothermal alterations. Shortwave infrared (SWIR) bands from Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) with the wavelength of ASTER SWIR bands between 1.65 and 2.43 μm has a good potential for mapping a hydrothermal alteration minerals such as alunite, pyrophyllite, kaolinite, illite-muscovite-sericite, and carbonate. In this range, hydroxide minerals which have been produced by hydrothermal alteration exhibit good absorption compared to shorter or longer wavelengths. In this research which aims to remove atmospheric and topographic effects from ASTER SWIR data, the authors used the log-residual method (LRM) with the minimum noise fraction (MNF) transformation to create a pixel purity index (PPI) which was used to extract the most spectrally pure pixels from multispectral images. Spectral analyses of the clay mineralogy of the study area (east Zanjan, in northern Iran) were obtained by matching the unknown spectra of the purest pixels to the U.S. Geological Survey (USGS) mineral library. Three methods, spectral feature fitting (SFF), spectral angle mapping (SAM), and binary encoding (BE) were used to generate a score between 0 and 1, where a value of 1 indicates a perfect match showing the exact mineral type. In this way, it was possible to identify certain mineral classes, including chlorite, carbonate, calcite-dolomite-magnesite, kaolinite-smectite, alunite, and illite. In this research, two main propylitic and phyllic-argillic zones could be separated using their compositions of these minerals. These two alteration zones are important for porphyry copper deposits and gold mineralization in this part of Iran.

  12. Correction for tissue optical properties enables quantitative skin fluorescence measurements using multi-diameter single fiber reflectance spectroscopy.

    PubMed

    Middelburg, T A; Hoy, C L; Neumann, H A M; Amelink, A; Robinson, D J

    2015-07-01

    Fluorescence measurements in the skin are very much affected by absorption and scattering but existing methods to correct for this are not applicable to superficial skin measurements. The first use of multiple-diameter single fiber reflectance (MDSFR) and single fiber fluorescence (SFF) spectroscopy in human skin was investigated. MDSFR spectroscopy allows a quantification of the full optical properties in superficial skin (μa, μs' and γ), which can next be used to retrieve the corrected - intrinsic - fluorescence of a fluorophore Qμa,x(f). Our goal was to investigate the importance of such correction for individual patients. We studied this in 22 patients undergoing photodynamic therapy (PDT) for actinic keratosis. The magnitude of correction of fluorescence was around 4 (for both autofluorescence and protoporphyrin IX). Moreover, it was variable between patients, but also within patients over the course of fractionated aminolevulinic acid PDT (range 2.7-7.5). Patients also varied in the amount of protoporphyrin IX synthesis, photobleaching percentages and resynthesis (>100× difference between the lowest and highest PpIX synthesis). The autofluorescence was lower in actinic keratosis than contralateral normal skin (0.0032 versus 0.0052; P<0.0005). Our results clearly demonstrate the importance of correcting the measured fluorescence for optical properties, because these vary considerably between individual patients and also during PDT. Protoporphyrin IX synthesis and photobleaching kinetics allow monitoring clinical PDT which facilitates individual-based PDT dosing and improvement of clinical treatment protocols. Furthermore, the skin autofluorescence can be relevant for diagnostic use in the skin, but it may also be interesting because of its association with several internal diseases. Copyright © 2015 Japanese Society for Investigative Dermatology. Published by Elsevier Ireland Ltd. All rights reserved.

  13. Electromagnetic and axial-vector form factors of the quarks and nucleon

    NASA Astrophysics Data System (ADS)

    Dahiya, Harleen; Randhawa, Monika

    2017-11-01

    In light of the improved precision of the experimental measurements and enormous theoretical progress, the nucleon form factors have been evaluated with an aim to understand how the static properties and dynamical behavior of nucleons emerge from the theory of strong interactions between quarks. We have analyzed the vector and axial-vector nucleon form factors (GE,Mp,n(Q2) and GAp,n(Q2)) using the spin observables in the chiral constituent quark model (χCQM) which has made a significant contribution to the unraveling of the internal structure of the nucleon in the nonperturbative regime. We have also presented a comprehensive analysis of the flavor decomposition of the form factors (GEq(Q2), GMq(Q2) and GAq(Q2) for q = u,d,s) within the framework of χCQM with emphasis on the extraction of the strangeness form factors which are fundamental to determine the spin structure and test the chiral symmetry breaking effects in the nucleon. The Q2 dependence of the vector and axial-vector form factors of the nucleon has been studied using the conventional dipole form of parametrization. The results are in agreement with the available experimental data.

  14. Orthopositronium decay form factors and two-photon correlations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Adkins, Gregory S.; Droz, Daniel R.; Rastawicki, Dominik

    2010-04-15

    We give results for the orthopositronium decay form factors through one-loop order. We use the form factors to calculate momentum correlations of the final-state photons and , including one-loop corrections, for ensembles of initial orthopositronium atoms having arbitrary polarization.

  15. Heavy quark form factors at two loops

    NASA Astrophysics Data System (ADS)

    Ablinger, J.; Behring, A.; Blümlein, J.; Falcioni, G.; De Freitas, A.; Marquard, P.; Rana, N.; Schneider, C.

    2018-05-01

    We compute the two-loop QCD corrections to the heavy quark form factors in the case of the vector, axial-vector, scalar and pseudoscalar currents up to second order in the dimensional parameter ɛ =(4 -D )/2 . These terms are required in the renormalization of the higher-order corrections to these form factors.

  16. TRASYS form factor matrix normalization

    NASA Technical Reports Server (NTRS)

    Tsuyuki, Glenn T.

    1992-01-01

    A method has been developed for adjusting a TRASYS enclosure form factor matrix to unity. This approach is not limited to closed geometries, and in fact, it is primarily intended for use with open geometries. The purpose of this approach is to prevent optimistic form factors to space. In this method, nodal form factor sums are calculated within 0.05 of unity using TRASYS, although deviations as large as 0.10 may be acceptable, and then, a process is employed to distribute the difference amongst the nodes. A specific example has been analyzed with this method, and a comparison was performed with a standard approach for calculating radiation conductors. In this comparison, hot and cold case temperatures were determined. Exterior nodes exhibited temperature differences as large as 7 C and 3 C for the hot and cold cases, respectively when compared with the standard approach, while interior nodes demonstrated temperature differences from 0 C to 5 C. These results indicate that temperature predictions can be artificially biased if the form factor computation error is lumped into the individual form factors to space.

  17. Relativistic corrections to the form factors of Bc into P-wave orbitally excited charmonium

    NASA Astrophysics Data System (ADS)

    Zhu, Ruilin

    2018-06-01

    We investigated the form factors of the Bc meson into P-wave orbitally excited charmonium using the nonrelativistic QCD effective theory. Through the analytic computation, the next-to-leading order relativistic corrections to the form factors were obtained, and the asymptotic expressions were studied in the infinite bottom quark mass limit. Employing the general form factors, we discussed the exclusive decays of the Bc meson into P-wave orbitally excited charmonium and a light meson. We found that the relativistic corrections lead to a large correction for the form factors, which makes the branching ratios of the decay channels B (Bc ± →χcJ (hc) +π± (K±)) larger. These results are useful for the phenomenological analysis of the Bc meson decays into P-wave charmonium, which shall be tested in the LHCb experiments.

  18. Proton Form Factors Measurements in the Time-Like Region

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Anulli, F.; /Frascati

    2007-10-22

    I present an overview of the measurement of the proton form factors in the time-like region. BABAR has recently measured with great accuracy the e{sup +}e{sup -} {yields} p{bar p} reaction from production threshold up to an energy of {approx} 4.5 GeV, finding evidence for a ratio of the electric to magnetic form factor greater than unity, contrary to expectation. In agreement with previous measurements, BABAR confirmed the steep rise of the magnetic form factor close to the p{bar p} mass threshold, suggesting the possible presence of an under-threshold N{bar N} vector state. These and other open questions related tomore » the nucleon form factors both in the time-like and space-like region, wait for more data with different experimental techniques to be possibly solved.« less

  19. Future Perspectives on Baryon Form Factor Measurements with BES III

    NASA Astrophysics Data System (ADS)

    Schönning, Karin; Li, Cui

    2017-03-01

    The electromagnetic structure of hadrons, parameterised in terms of electromagnetic form factors, EMFF's, provide a key to the strong interaction. Nucleon EMFF's have been studied rigorously for more than 60 years but the new techniques and larger data samples available at modern facilities have given rise to a renewed interest for the field. Recently, the access to hyperon structure by hyperon time-like EMFF provides an additional dimension. The BEijing Spectrometer (BES III) at the Beijing Electron Positron Collider (BEPC-II) in China is the only running experiment where time-like baryon EMFF's can be studied in the e+e- → BB̅ reaction. The BES III detector is an excellent tool for baryon form factor measurements thanks to its near 4π coverage, precise tracking, PID and calorimetry. All hyperons in the SU(3) spin 1/2 octet and spin 3/2 decuplet are energetically accessible within the BEPC-II energy range. Recent data on proton and Λ hyperon form factors will be presented. Furthermore, a world-leading data sample was collected in 2014-2015 for precision measurements of baryon form factors. In particular, the data will enable a measurement of the relative phase between the electric and the magnetic form factors for Λ and Λc+ and hyperons. The modulus of the phase can be extracted from the hyperon polarisation, which in turn is experimentally accessible via the weak, parity violating decay. Furthermore, from the spin correlation between the outgoing hyperon and antihyperon, the sign of the phase can be extracted. This means that the time-like form factors can be completely determined for the first time. The methods will be outlined and the prospects of the BES III form factor measurements will be given. We will also present a planned upgrade of the BES III detector which is expected to improve future form factor measurements.

  20. 77 FR 61830 - Proposed Collection; Comment Request for Information Collection Tools

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-11

    ... Form 8876, Excise Tax on Structured Settlement Factoring Transactions; Form 944-SS, Employer's ANNUAL...: (1) Title: Excise Tax on Structured Settlement Factoring Transactions. OMB Number: 1545-1826. Form...

  1. The use of the bi-factor model to test the uni-dimensionality of a battery of reasoning tests.

    PubMed

    Primi, Ricardo; Rocha da Silva, Marjorie Cristina; Rodrigues, Priscila; Muniz, Monalisa; Almeida, Leandro S

    2013-02-01

    The Battery of Reasoning Tests 5 (BPR-5) aims to assess the reasoning ability of individuals, using sub-tests with different formats and contents that require basic processes of inductive and deductive reasoning for their resolution. The BPR has three sequential forms: BPR-5i (for children from first to fifth grade), BPR-5 - Form A (for children from sixth to eighth grade) and BPR-5 - form B (for high school and undergraduate students). The present study analysed 412 questionnaires concerning BPR-5i, 603 questionnaires concerning BPR-5 - Form A and 1748 questionnaires concerning BPR-5 - Form B. The main goal was to test the uni-dimensionality of the battery and its tests in relation to items using the bi-factor model. Results suggest that the g factor loadings (extracted by the uni-dimensional model) do not change when the data is adjusted for a more flexible multi-factor model (bi-factor model). A general reasoning factor underlying different contents items is supported.

  2. Constraints on the [Formula: see text] form factor from analyticity and unitarity.

    PubMed

    Ananthanarayan, B; Caprini, I; Kubis, B

    Motivated by the discrepancies noted recently between the theoretical calculations of the electromagnetic [Formula: see text] form factor and certain experimental data, we investigate this form factor using analyticity and unitarity in a framework known as the method of unitarity bounds. We use a QCD correlator computed on the spacelike axis by operator product expansion and perturbative QCD as input, and exploit unitarity and the positivity of its spectral function, including the two-pion contribution that can be reliably calculated using high-precision data on the pion form factor. From this information, we derive upper and lower bounds on the modulus of the [Formula: see text] form factor in the elastic region. The results provide a significant check on those obtained with standard dispersion relations, confirming the existence of a disagreement with experimental data in the region around [Formula: see text].

  3. Strange nucleon electromagnetic form factors from lattice QCD

    NASA Astrophysics Data System (ADS)

    Alexandrou, C.; Constantinou, M.; Hadjiyiannakou, K.; Jansen, K.; Kallidonis, C.; Koutsou, G.; Avilés-Casco, A. Vaquero

    2018-05-01

    We evaluate the strange nucleon electromagnetic form factors using an ensemble of gauge configurations generated with two degenerate maximally twisted mass clover-improved fermions with mass tuned to approximately reproduce the physical pion mass. In addition, we present results for the disconnected light quark contributions to the nucleon electromagnetic form factors. Improved stochastic methods are employed leading to high-precision results. The momentum dependence of the disconnected contributions is fitted using the model-independent z-expansion. We extract the magnetic moment and the electric and magnetic radii of the proton and neutron by including both connected and disconnected contributions. We find that the disconnected light quark contributions to both electric and magnetic form factors are nonzero and at the few percent level as compared to the connected. The strange form factors are also at the percent level but more noisy yielding statistical errors that are typically within one standard deviation from a zero value.

  4. Renormalization group analysis of B →π form factors with B -meson light-cone sum rules

    NASA Astrophysics Data System (ADS)

    Shen, Yue-Long; Wei, Yan-Bing; Lü, Cai-Dian

    2018-03-01

    Within the framework of the B -meson light-cone sum rules, we review the calculation of radiative corrections to the three B →π transition form factors at leading power in Λ /mb. To resum large logarithmic terms, we perform the complete renormalization group evolution of the correlation function. We employ the integral transformation which diagonalizes evolution equations of the jet function and the B -meson light-cone distribution amplitude to solve these evolution equations and obtain renormalization group improved sum rules for the B →π form factors. Results of the form factors are extrapolated to the whole physical q2 region and are compared with that of other approaches. The effect of B -meson three-particle light-cone distribution amplitudes, which will contribute to the form factors at next-to-leading power in Λ /mb at tree level, is not considered in this paper.

  5. New Precision Limit on the Strange Vector Form Factors of the Proton

    DOE PAGES

    Ahmed, Z.; Allada, K.; Aniol, K. A.; ...

    2012-03-01

    The parity-violating cross-section asymmetry in the elastic scattering of polarized electrons from unpolarized protons has been measured at a four-momentum transfer squared Q 2 = 0.624 GeV 2 and beam energy E b = 3.48 GeV to be A PV = -23.80 ± 0.78 (stat) ± 0.36 (syst) parts per million. This result is consistent with zero contribution of strange quarks to the combination of electric and magnetic form factors G E s + 0.517 G M s = 0.003 ± 0.010 (stat) ± 0.004 (syst) ± 0.009 (ff), where the third error is due to the limits of precisionmore » on the electromagnetic form factors and radiative corrections. With this measurement, the world data on strange contributions to nucleon form factors are seen to be consistent with zero and not more than a few percent of the proton form factors.« less

  6. Analysis of vestibular-balance symptoms according to symptom duration: dimensionality of the Vertigo Symptom Scale-short form.

    PubMed

    Kondo, Masaki; Kiyomizu, Kensuke; Goto, Fumiyuki; Kitahara, Tadashi; Imai, Takao; Hashimoto, Makoto; Shimogori, Hiroaki; Ikezono, Tetsuo; Nakayama, Meiho; Watanabe, Norio; Akechi, Tatsuo

    2015-01-22

    Dizziness or vertigo is associated with both vestibular-balance and psychological factors. A common assessment tool is the Vertigo Symptom Scale (VSS) -short form, which has two subscales: vestibular-balance and autonomic-anxiety. Despite frequent use, the factor structure of the VSS-short form has yet to be confirmed. Here, we clarified the factor structure of the VSS-short form, and assessed the validity and reliability of the Japanese version of this tool. We conducted a cross-sectional, multicenter, psychometric evaluation of patients with non-central dizziness or vertigo persisting for longer than 1 month. Participants completed the VSS-short form, the Dizziness Handicap Inventory, and the Hospital Anxiety and Depression Scale. They also completed the VSS-short form a second time 1-3 days later. The questionnaire was translated into Japanese and cross-culturally adapted. We conducted a confirmatory factor analysis followed by an exploratory factor analysis. Convergent and discriminant validity, internal consistency, and test-retest reliability were evaluated. The total sample and retest sample consisted of 159 and 79 participants, respectively. Model-fitting for a two-subscale structure in a confirmatory factor analysis was poor. An exploratory factor analysis produced a three-factor structure: long-duration vestibular-balance symptoms, short-duration vestibular-balance symptoms, and autonomic-anxiety symptoms. Regarding convergent and discriminant validity, all hypotheses were clearly supported. We obtained high Cronbach's α coefficients for the total score and subscales, ranging from 0.758 to 0.866. Total score and subscale interclass correlation coefficients for test-retest reliability were acceptable, ranging from 0.867 to 0.897. The VSS-short form has a three-factor structure that was cross-culturally well-matched with previous data from the VSS-long version. Thus, it was suggested that vestibular-balance symptoms can be analyzed separately according to symptom duration, which may reflect pathophysiological factors. The VSS-short form can be used to evaluate vestibular-balance symptoms and autonomic-anxiety symptoms, as well as the duration of vestibular-balance symptoms. Further research using the VSS-short form should be required in other languages and populations.

  7. Relationship Domain of Form Six Teachers Thinking in Teaching with External Factors of Form Six Teachers

    ERIC Educational Resources Information Center

    bin Pet, Mokhtar; Sihes, Ahmad Johari Hj

    2015-01-01

    This study aims to examine the external factors of form six teachers who can influence thinking domain form six teachers in their teaching. This study was conducted using a quantitative approach using questionnaires. A total of 300 form six teacher schools in Johor were chosen as respondents. The findings were obtained as student background…

  8. Gluing operation and form factors of local operators in N = 4 Super Yang-Mills theory

    NASA Astrophysics Data System (ADS)

    Bolshov, A. E.

    2018-04-01

    The gluing operation is an effective way to get form factors of both local and non-local operators starting from different representations of on-shell scattering amplitudes. In this paper it is shown how it works on the example of form factors of operators from stress-tensor operator supermultiplet in Grassmannian and spinor helicity representations.

  9. Factors Influencing Students' Achievement in Form 5 Islamic Studies Subject

    ERIC Educational Resources Information Center

    bin Che Noh, Mohd Aderi; Omar, Noraini binti; bin Kasan, Hasnan

    2013-01-01

    This study is aimed at analyzing the factors influencing the achievements of students in the subject of Islamic Studies for Form 5 SPM (KBSM) in schools in the area of Samarahan, Sarawak. The factors analysed is attitude and interest. This is a survey based study and data was compiled from the survey forms which had the topic "Factors…

  10. ω→π0γ* and ϕ→π0γ* transition form factors in dispersion theory

    NASA Astrophysics Data System (ADS)

    Schneider, Sebastian P.; Kubis, Bastian; Niecknig, Franz

    2012-09-01

    We calculate the ω→π0γ* and ϕ→π0γ* electromagnetic transition form factors based on dispersion theory, relying solely on a previous dispersive analysis of the corresponding three-pion decays and the pion vector form factor. We compare our findings to recent measurements of the ω→π0μ+μ- decay spectrum by the NA60 collaboration, and strongly encourage experimental investigation of the Okubo-Zweig-Iizuka forbidden ϕ→π0ℓ+ℓ- decays in order to understand the strong deviations from vector-meson dominance found in these transition form factors.

  11. Flavor dependence of the pion and kaon form factors and parton distribution functions

    DOE PAGES

    Hutauruk, Parada T. P.; Cloët, Ian C.; Thomas, Anthony W.

    2016-09-01

    The separate quark flavor contributions to the pion and kaon valence quark distribution functions are studied, along with the corresponding electromagnetic form factors in the space-like region. The calculations are made using the solution of the Bethe-Salpeter equation for the model of Nambu and Jona-Lasinio with proper-time regularization. Both the pion and kaon form factors and the valence quark distribution functions reproduce many features of the available empirical data. The larger mass of the strange quark naturally explains the empirical fact that the ratio u(K) + (x)/u(pi) + (x) drops below unity at large x, with a value of approximately Mmore » $$2\\atop{u}$$/Ms$$2\\atop{s}$$ as x → 1. With regard to the elastic form factors we report a large flavor dependence, with the u-quark contribution to the kaon form factor being an order of magnitude smaller than that of the s-quark at large Q 2, which may be a sensitive measure of confinement effects in QCD. Surprisingly though, the total K + and π + form factors differ by only 10%. Lastly, in general we find that flavor breaking effects are typically around 20%.« less

  12. Flavor dependence of the pion and kaon form factors and parton distribution functions

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hutauruk, Parada T. P.; Cloët, Ian C.; Thomas, Anthony W.

    The separate quark flavor contributions to the pion and kaon valence quark distribution functions are studied, along with the corresponding electromagnetic form factors in the space-like region. The calculations are made using the solution of the Bethe-Salpeter equation for the model of Nambu and Jona-Lasinio with proper-time regularization. Both the pion and kaon form factors and the valence quark distribution functions reproduce many features of the available empirical data. The larger mass of the strange quark naturally explains the empirical fact that the ratio u(K) + (x)/u(pi) + (x) drops below unity at large x, with a value of approximately Mmore » $$2\\atop{u}$$/Ms$$2\\atop{s}$$ as x → 1. With regard to the elastic form factors we report a large flavor dependence, with the u-quark contribution to the kaon form factor being an order of magnitude smaller than that of the s-quark at large Q 2, which may be a sensitive measure of confinement effects in QCD. Surprisingly though, the total K + and π + form factors differ by only 10%. Lastly, in general we find that flavor breaking effects are typically around 20%.« less

  13. 48 CFR 247.372 - DD Form 1654, Evaluation of Transportation Cost Factors.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false DD Form 1654, Evaluation... Transportation in Supply Contracts 247.372 DD Form 1654, Evaluation of Transportation Cost Factors. Contracting personnel may use the DD Form 1654 to furnish information to the transportation office for development of...

  14. 75 FR 32199 - Agency Information Collection Activities: Submission for OMB Review; Comment Request, OMB No...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-07

    ... Change Endorsement; FEMA Form 086-0-5, Flood Insurance Preferred Risk Policy Application; FEMA Form 086-0-4, V-Zone Risk Factor Rating Form and Instructions. SUMMARY: The Federal Emergency Management Agency... Risk Factor Rating Form and Instructions. Abstract: In order to provide for the availability of...

  15. The subscales and short forms of the dizziness handicap inventory: are they useful for comparison of the patient groups?

    PubMed

    Ardıç, Fazıl Necdet; Tümkaya, Funda; Akdağ, Beyza; Şenol, Hande

    2017-10-01

    Dizziness Handicap Inventory (DHI) is one of the most frequently used surveys for vertigo. The aim of the study was re-analyze the consistency of subscales and correlation between original and different short forms. The data of 2111 patients were analyzed. Original three subscales, screening form of DHI and short form of DHI were evaluated. The suitability of the data set for factor analysis and factor structure was analyzed with Kaiser-Meyer-Olkin (KMO) coefficient, Bartlett's Sphericity Test, and Varimax method. Pearson correlation analysis was performed. Factor analysis showed that two factor solutions are more prominent in our data. The factors proposed in different studies are not in harmony with each other. There is high correlation between the original and screening and short forms of DHI. This study indicated that the factor structure of the scale was not consistent. It is not advised to use subscale scores for comparison especially in international level. Therefore, total score should be used rather than the scores of the subscales. Using DHI screening form instead of original 25 questions is more convenient, because it is highly correlated with the original one and has fewer questions. Implications for rehabilitation Factor structure of the DHI is not consistent enough for comparison of the international studies. Total score of DHI is reliable. Using the screening version of DHI is better, because it is highly correlated with the original form and has fewer questions (10 questions).

  16. Development of a short-form Learning Organization Survey: the LOS-27.

    PubMed

    Singer, Sara J; Moore, Scott C; Meterko, Mark; Williams, Sandra

    2012-08-01

    Despite urgent need for innovation, adaptation, and change in health care, few tools enable researchers or practitioners to assess the extent to which health care facilities perform as learning organizations or the effects of initiatives that require learning. This study's objective was to develop and test a short-form Learning Organization Survey to fill this gap. The authors applied exploratory factor analysis and confirmatory factor analysis to data from Veterans Health Administration personnel to derive a short-form survey and then conducted further confirmatory factor analysis and factor invariance testing on additional Veterans Health Administration data to evaluate the short form. Results suggest that a 27-item, 7-factor survey (2 environmental factors, 1 on leadership, and 4 on concrete learning processes and practices) reliably measures key features of organizational learning, allowing researchers to evaluate theoretical propositions about organizational learning, its antecedents, and outcomes and enabling managers to assess and enhance organizations' learning capabilities and performance.

  17. Set of Criteria for Efficiency of the Process Forming the Answers to Multiple-Choice Test Items

    ERIC Educational Resources Information Center

    Rybanov, Alexander Aleksandrovich

    2013-01-01

    Is offered the set of criteria for assessing efficiency of the process forming the answers to multiple-choice test items. To increase accuracy of computer-assisted testing results, it is suggested to assess dynamics of the process of forming the final answer using the following factors: loss of time factor and correct choice factor. The model…

  18. The structure of the nucleon: Elastic electromagnetic form factors

    DOE PAGES

    Punjabi, V.; Perdrisat, C. F.; Jones, M. K.; ...

    2015-07-10

    Precise proton and neutron form factor measurements at Jefferson Lab, using spin observables, have recently made a significant contribution to the unraveling of the internal structure of the nucleon. Accurate experimental measurements of the nucleon form factors are a test-bed for understanding how the nucleon's static properties and dynamical behavior emerge from QCD, the theory of the strong interactions between quarks. There has been enormous theoretical progress, since the publication of the Jefferson Lab proton form factor ratio data, aiming at reevaluating the picture of the nucleon. We will review the experimental and theoretical developments in this field and discussmore » the outlook for the future.« less

  19. Antisymmetrization effects and the form factor of the real part of the. cap alpha. -nucleus potential

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Majka, Z.; Budzanowski, A.; Grotowski, K.

    1978-07-01

    Antisymmetrization effects in the ..cap alpha..-nucleus interaction are investigated on the basis of a microscopic model in an one nucleon exchange approximation. It influences the form factor, increasing the halfway radius and decreasing the diffuseness as compared with the direct term of the potential only. Antisymmetrization preserves the shape of the potential which can be parametrized by a Woods-Saxon squared form. The phenomenological potential with the energy independent form factor of the above shape fits experimental data in a wide energy region.

  20. The electromagnetic Sigma-to-Lambda hyperon transition form factors at low energies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Granados, Carlos; Leupold, Stefan; Perotti, Elisabetta

    Using dispersion theory the low-energy electromagnetic form factors for the transition of a Sigma to a Lambda hyperon are related to the pion vector form factor. The additionally required input, i.e. the two-pion-Sigma-Lambda amplitudes are determined from relativistic next-to-leading-order (NLO) baryon chiral perturbation theory including the baryons from the octet and optionally from the decuplet. Pion rescattering is again taken into account by dispersion theory. It turns out that the inclusion of decuplet baryons is not an option but a necessity to obtain reasonable results. The electric transition form factor remains very small in the whole low-energy region. The magneticmore » transition form factor depends strongly on one not very well determined low-energy constant of the NLO Lagrangian. Furthermore, one obtains reasonable predictive power if this low-energy constant is determined from a measurement of the magnetic transition radius. Such a measurement can be performed at the future Facility for Antiproton and Ion Research (FAIR).« less

  1. Factor structure and psychometric properties of the Fertility Problem Inventory–Short Form

    PubMed Central

    Zurlo, Maria Clelia; Cattaneo Della Volta, Maria Franscesca; Vallone, Federica

    2017-01-01

    The study analyses factor structure and psychometric properties of the Italian version of the Fertility Problem Inventory–Short Form. A sample of 206 infertile couples completed the Italian version of Fertility Problem Inventory (46 items) with demographics, State Anxiety Scale of State-Trait Anxiety Inventory (Form Y), Edinburgh Depression Scale and Dyadic Adjustment Scale, used to assess convergent and discriminant validity. Confirmatory factor analysis was unsatisfactory (comparative fit index = 0.87; Tucker-Lewis Index = 0.83; root mean square error of approximation = 0.17), and Cronbach’s α (0.95) revealed a redundancy of items. Exploratory factor analysis was carried out deleting cross-loading items, and Mokken scale analysis was applied to verify the items homogeneity within the reduced subscales of the questionnaire. The Fertility Problem Inventory–Short Form consists of 27 items, tapping four meaningful and reliable factors. Convergent and discriminant validity were confirmed. Findings indicated that the Fertility Problem Inventory–Short Form is a valid and reliable measure to assess infertility-related stress dimensions. PMID:29379625

  2. The electromagnetic Sigma-to-Lambda hyperon transition form factors at low energies

    DOE PAGES

    Granados, Carlos; Leupold, Stefan; Perotti, Elisabetta

    2017-06-09

    Using dispersion theory the low-energy electromagnetic form factors for the transition of a Sigma to a Lambda hyperon are related to the pion vector form factor. The additionally required input, i.e. the two-pion-Sigma-Lambda amplitudes are determined from relativistic next-to-leading-order (NLO) baryon chiral perturbation theory including the baryons from the octet and optionally from the decuplet. Pion rescattering is again taken into account by dispersion theory. It turns out that the inclusion of decuplet baryons is not an option but a necessity to obtain reasonable results. The electric transition form factor remains very small in the whole low-energy region. The magneticmore » transition form factor depends strongly on one not very well determined low-energy constant of the NLO Lagrangian. Furthermore, one obtains reasonable predictive power if this low-energy constant is determined from a measurement of the magnetic transition radius. Such a measurement can be performed at the future Facility for Antiproton and Ion Research (FAIR).« less

  3. From quarks and gluons to baryon form factors.

    PubMed

    Eichmann, Gernot

    2012-04-01

    I briefly summarize recent results for nucleon and [Formula: see text] electromagnetic, axial and transition form factors in the Dyson-Schwinger approach. The calculation of the current diagrams from the quark-gluon level enables a transparent discussion of common features such as: the implications of dynamical chiral symmetry breaking and quark orbital angular momentum, the timelike structure of the form factors, and their interpretation in terms of missing pion-cloud effects.

  4. Soil Forming Factors

    Science.gov Websites

    It! What is Soil? Chip Off the Old Block Soil Forming Factors Matters of Life and Death Underneath It All Wise Choices A World of Soils << 1 Soil Forming Factors 2 A Top to Bottom Guide 3 Making a Soil Monolith 4 Soil Orders 5 State Soil Monoliths 6 Where in the Soil World Are You? >> A Top to

  5. Chiral behavior of K →π l ν decay form factors in lattice QCD with exact chiral symmetry

    NASA Astrophysics Data System (ADS)

    Aoki, S.; Cossu, G.; Feng, X.; Fukaya, H.; Hashimoto, S.; Kaneko, T.; Noaki, J.; Onogi, T.; Jlqcd Collaboration

    2017-08-01

    We calculate the form factors of the K →π l ν semileptonic decays in three-flavor lattice QCD and study their chiral behavior as a function of the momentum transfer and the Nambu-Goldstone boson masses. Chiral symmetry is exactly preserved by using the overlap quark action, which enables us to directly compare the lattice data with chiral perturbation theory (ChPT). We generate gauge ensembles at a lattice spacing of 0.11 fm with four pion masses covering 290-540 MeV and a strange quark mass ms close to its physical value. By using the all-to-all quark propagator, we calculate the vector and scalar form factors with high precision. Their dependence on ms and the momentum transfer is studied by using the reweighting technique and the twisted boundary conditions for the quark fields. We compare the results for the semileptonic form factors with ChPT at next-to-next-to-leading order in detail. While many low-energy constants appear at this order, we make use of our data of the light meson electromagnetic form factors in order to control the chiral extrapolation. We determine the normalization of the form factors as f+(0 )=0.9636 (36 )(-35+57) and observe reasonable agreement of their shape with experiment.

  6. {lambda}{sub b}{yields}p, {lambda} transition form factors from QCD light-cone sum rules

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wang Yuming; Lue Caidian; Shen Yuelong

    2009-10-01

    Light-cone sum rules for the {lambda}{sub b}{yields}p, {lambda} transition form factors are derived from the correlation functions expanded by the twist of the distribution amplitudes of the {lambda}{sub b} baryon. In terms of the {lambda}{sub b} three-quark distribution amplitude models constrained by the QCD theory, we calculate the form factors at small momentum transfers and compare the results with those estimated in the conventional light-cone sum rules (LCSR) and perturbative QCD approaches. Our results indicate that the two different versions of sum rules can lead to the consistent numbers of form factors responsible for {lambda}{sub b}{yields}p transition. The {lambda}{sub b}{yields}{lambda}more » transition form factors from LCSR with the asymptotic {lambda} baryon distribution amplitudes are found to be almost 1 order larger than those obtained in the {lambda}{sub b}-baryon LCSR, implying that the preasymptotic corrections to the baryonic distribution amplitudes are of great importance. Moreover, the SU(3) symmetry breaking effects between the form factors f{sub 1}{sup {lambda}{sub b}}{sup {yields}}{sup p} and f{sub 1}{sup {lambda}{sub b}}{sup {yields}}{sup {lambda}} are computed as 28{sub -8}{sup +14}% in the framework of {lambda}{sub b}-baryon LCSR.« less

  7. Constraints on the ωπ Form Factor from Analyticity and Unitarity

    NASA Astrophysics Data System (ADS)

    Ananthanarayan, B.; Caprini, Irinel; Kubis, Bastian

    Form factors are important low-energy quantities and an accurate knowledge of these sheds light on the strong interactions. A variety of methods based on general principles have been developed to use information known in different energy regimes to constrain them in regions where experimental information needs to be tested precisely. Here we review our recent work on the electromagnetic ωπ form factor in a model-independent framework known as the method of unitarity bounds, partly motivated by the discre-pancies noted recently between the theoretical calculations of the form factor based on dispersion relations and certain experimental data measured from the decay ω → π0γ*. We have applied a modified dispersive formalism, which uses as input the discontinuity of the ωπ form factor calculated by unitarity below the ωπ threshold and an integral constraint on the square of its modulus above this threshold. The latter constraint was obtained by exploiting unitarity and the positivity of the spectral function of a QCD correlator, computed on the spacelike axis by operator product expansion and perturbative QCD. An alternative constraint is obtained by using data available at higher energies for evaluating an integral of the modulus squared with a suitable weight function. From these conditions we derived upper and lower bounds on the modulus of the ωπ form factor in the region below the ωπ threshold. The results confirm the existence of a disagreement between dispersion theory and experimental data on the ωπ form factor around 0:6 GeV, including those from NA60 published in 2016.

  8. Constraints on the ωπ form factor from analyticity and unitarity

    NASA Astrophysics Data System (ADS)

    Ananthanarayan, B.; Caprini, Irinel; Kubis, Bastian

    2016-05-01

    Form factors are important low-energy quantities and an accurate knowledge of these sheds light on the strong interactions. A variety of methods based on general principles have been developed to use information known in different energy regimes to constrain them in regions where experimental information needs to be tested precisely. Here we review our recent work on the electromagnetic ωπ form factor in a model-independent framework known as the method of unitarity bounds, partly motivated by the discrepancies noted recently between the theoretical calculations of the form factor based on dispersion relations and certain experimental data measured from the decay ω → π0γ∗. We have applied a modified dispersive formalism, which uses as input the discontinuity of the ωπ form factor calculated by unitarity below the ωπ threshold and an integral constraint on the square of its modulus above this threshold. The latter constraint was obtained by exploiting unitarity and the positivity of the spectral function of a QCD correlator, computed on the spacelike axis by operator product expansion and perturbative QCD. An alternative constraint is obtained by using data available at higher energies for evaluating an integral of the modulus squared with a suitable weight function. From these conditions we derived upper and lower bounds on the modulus of the ωπ form factor in the region below the ωπ threshold. The results confirm the existence of a disagreement between dispersion theory and experimental data on the ωπ form factor around 0.6 GeV, including those from NA60 published in 2016.

  9. Calculation of neutral weak nucleon form factors with the AdS/QCD correspondence

    NASA Astrophysics Data System (ADS)

    Lohmann, Mark

    The AdS/QCD (Anti-de Sitter/Quantum Chromodynamics) is a mathematical formalism applied to a theory based on the original AdS/CFT (Anti-de Sitter/ Conformal Field Theory) correspondence. The aim is to describe properties of the strong force in an essentially non-perturbative way. AdS/QCD theories break the conformal symmetry of the AdS metric (a sacrifice) to arrive at a boundary theory which is QCD-like (a payoff). This correspondence has been used to calculate well-known quantities in nucleon spectra and structure like Regge trajectories, form factors, and many others within an error of less than 20% from experiment. This is impressive considering that ordinary perturbation theory in QCD applied to the strongly interacting domain usually obtains an error of about 30%. In this thesis, the AdS/QCD correspondence method of light-front holography established by Brodsky and de Teramond is used in an attempt to calculate the Dirac and Pauli neutral weak form factors, FZ1 (Q2) and FZ2 (Q 2) respectively, for both the proton and the neutron. With this approach, we were able to determine the neutral weak Dirac form factor for both nucleons and the Pauli form factor for the proton, while the method did not succeed at determining the neutral weak Pauli form factor for the neutron. With these we were also able to extract the proton's strange electric and magnetic form factor, which addresses important questions in nucleon sub-structure that are currently being investigated through experiments at the Thomas Jefferson National Accelerator Facility.

  10. Analysis of risk factors in the development of retinopathy of prematurity.

    PubMed

    Knezević, Sanja; Stojanović, Nadezda; Oros, Ana; Savić, Dragana; Simović, Aleksandra; Knezević, Jasmina

    2011-01-01

    Retinopathy of prematurity (ROP) is a multifactorial disease that occurs most frequently in very small and very sick preterm infants, and it has been identified as the major cause of childhood blindness. The aim of this study was to evaluate ROP incidence and risk factors associated with varying degrees of illness. The study was conducted at the Centre for Neonatology, Paediatric Clinic of the Clinical Centre Kragujevac, Serbia, in the period from June 2006 to December 2008. Ophthalmologic screening was performed in all children with body weight lower than 2000 g or gestational age lower than 36 weeks. We analyzed eighteen postnatal and six perinatal risk factors and the group correlations for each of the risk factors. Out of 317 children that were screened, 56 (17.7%) developed a mild form of ROP, while 68 (21.5%) developed a severe form. Univariate analysis revealed a large number of statistically significant risk factors for the development of ROP, especially the severe form. Multivariate logistical analysis further separated two independent risk factors: small birth weight (p = 0.001) and damage of central nervous system (p = 0.01). Independent risk factors for transition from mild to severe forms of ROP were identified as: small birth weight (p = 0.05) and perinatal risk factors (p = 0.02). Small birth weight and central nervous system damage were risk factors for the development of ROP, perinatal risk factors were identified as significant for transition from mild to severe form of ROP.

  11. Psychometric properties of the Swedish PedsQL, Pediatric Quality of Life Inventory 4.0 generic core scales.

    PubMed

    Petersen, Solveig; Hägglöf, Bruno; Stenlund, Hans; Bergström, Erik

    2009-09-01

    To study the psychometric performance of the Swedish version of the Pediatric Quality of Life Inventory (PedsQL) 4.0 generic core scales in a general child population in Sweden. PedsQL forms were distributed to 2403 schoolchildren and 888 parents in two different school settings. Reliability and validity was studied for self-reports and proxy reports, full forms and short forms. Confirmatory factor analysis tested the factor structure and multigroup confirmatory factor analysis tested measurement invariance between boys and girls. Test-retest reliability was demonstrated for all scales and internal consistency reliability was shown with alpha value exceeding 0.70 for all scales but one (self-report short form: social functioning). Child-parent agreement was low to moderate. The four-factor structure of the PedsQL and factorial invariance across sex subgroups were confirmed for the self-report forms and for the proxy short form, while model fit indices suggested improvement of several proxy full-form scales. The Swedish PedsQL 4.0 generic core scales are a reliable and valid tool for health-related quality of life (HRQoL) assessment in Swedish child populations. The proxy full form, however, should be used with caution. The study also support continued use of the PedsQL as a four-factor model, capable of revealing meaningful HRQoL differences between boys and girls.

  12. Extraction of the neutron electric form factor from measurements of inclusive double spin asymmetries

    NASA Astrophysics Data System (ADS)

    Sulkosky, V.; Jin, G.; Long, E.; Zhang, Y.-W.; Mihovilovic, M.; Kelleher, A.; Anderson, B.; Higinbotham, D. W.; Širca, S.; Allada, K.; Annand, J. R. M.; Averett, T.; Bertozzi, W.; Boeglin, W.; Bradshaw, P.; Camsonne, A.; Canan, M.; Cates, G. D.; Chen, C.; Chen, J.-P.; Chudakov, E.; De Leo, R.; Deng, X.; Deur, A.; Dutta, C.; El Fassi, L.; Flay, D.; Frullani, S.; Garibaldi, F.; Gao, H.; Gilad, S.; Gilman, R.; Glamazdin, O.; Golge, S.; Gomez, J.; Hansen, J.-O.; Holmstrom, T.; Huang, J.; Ibrahim, H.; de Jager, C. W.; Jensen, E.; Jiang, X.; Jones, M.; Kang, H.; Katich, J.; Khanal, H. P.; King, P.; Korsch, W.; LeRose, J.; Lindgren, R.; Lu, H.-J.; Luo, W.; Markowitz, P.; Meekins, D.; Meziane, M.; Michaels, R.; Moffit, B.; Monaghan, P.; Muangma, N.; Nanda, S.; Norum, B. E.; Pan, K.; Parno, D.; Piasetzky, E.; Posik, M.; Punjabi, V.; Puckett, A. J. R.; Qian, X.; Qiang, Y.; Qui, X.; Riordan, S.; Saha, A.; Sawatzky, B.; Shabestari, M.; Shahinyan, A.; Shoenrock, B.; John, J. St.; Subedi, R.; Tobias, W. A.; Tireman, W.; Urciuoli, G. M.; Wang, D.; Wang, K.; Wang, Y.; Watson, J.; Wojtsekhowski, B.; Ye, Z.; Zhan, X.; Zhang, Y.; Zheng, X.; Zhao, B.; Zhu, L.; Jefferson Lab Hall A Collaboration

    2017-12-01

    Background: Measurements of the neutron charge form factor, GEn, are challenging because the neutron has no net charge. In addition, measurements of the neutron form factors must use nuclear targets which require accurately accounting for nuclear effects. Extracting GEn with different targets and techniques provides an important test of our handling of these effects. Purpose: The goal of the measurement was to use an inclusive asymmetry measurement technique to extract the neutron charge form factor at a four-momentum transfer of 1 (GeV/c ) 2 . This technique has very different systematic uncertainties than traditional exclusive measurements and thus serves as an independent check of whether nuclear effects have been taken into account correctly. Method: The inclusive quasielastic reaction 3He ⃗(e ⃗,e') was measured at Jefferson Laboratory. The neutron electric form factor, GEn, was extracted at Q2=0.98 (GeV/c ) 2 from ratios of electron-polarization asymmetries measured for two orthogonal target spin orientations. This Q2 is high enough that the sensitivity to GEn is not overwhelmed by the neutron magnetic contribution, and yet low enough that explicit neutron detection is not required to suppress pion production. Results: The neutron electric form factor, GEn, was determined to be 0.0414 ±0.0077 (stat)±0.0022 (syst) , providing the first high-precision inclusive extraction of the neutron's charge form factor. Conclusions: The use of the inclusive quasielastic 3He ⃗(e ⃗,e') with a four-momentum transfer near 1 (GeV/c ) 2 has been used to provide a unique measurement of GEn. This new result provides a systematically independent validation of the exclusive extraction technique results and implies that the nuclear corrections are understood. This is contrary to the proton form factor where asymmetry and differential cross section measurements have been shown to have large systematic differences.

  13. Form Factor Evaluation of Open Body Area Network (OBAN) Physiological Status Monitoring (PSM) System Prototype Designs

    DTIC Science & Technology

    2018-05-11

    SYSTEM PROTOTYPE DESIGNS DISCLAIMERS The opinions or assertions contained herein are the private views of the author(s) and are not to be construed as...FORM FACTOR EVALUATION OF OPEN BODY AREA NETWORK (OBAN) PHYSIOLOGICAL STATUS MONITORING (PSM) SYSTEM PROTOTYPE DESIGNS William J...security; and is designed to function for 72 hours or more. The test described in this report assesses proposed form-factor designs . Feedback using

  14. Electric and magnetic form factors of strange baryons

    NASA Astrophysics Data System (ADS)

    Van Cauteren, T.; Merten, D.; Corthals, T.; Janssen, S.; Metsch, B.; Petry, H.-R.; Ryckebusch, J.

    . Predictions for the electromagnetic form factors of the Λ , Σ and Ξ hyperons are presented. The numerical calculations are performed within the framework of the fully relativistic constituent-quark model developed by the Bonn group. The computed magnetic moments compare favorably with the experimentally known values. Most magnetic form factors GM (Q2) can be parameterized in terms of a dipole with cutoff masses ranging from 0.79 to 1.14 GeV.

  15. From quarks and gluons to baryon form factors

    PubMed Central

    Eichmann, Gernot

    2012-01-01

    I briefly summarize recent results for nucleon and Δ(1232) electromagnetic, axial and transition form factors in the Dyson–Schwinger approach. The calculation of the current diagrams from the quark–gluon level enables a transparent discussion of common features such as: the implications of dynamical chiral symmetry breaking and quark orbital angular momentum, the timelike structure of the form factors, and their interpretation in terms of missing pion-cloud effects. PMID:26766879

  16. The QCD form factor of heavy quarks at NNLO

    NASA Astrophysics Data System (ADS)

    Gluza, J.; Mitov, A.; Moch, S.; Riemann, T.

    2009-07-01

    We present an analytical calculation of the two-loop QCD corrections to the electromagnetic form factor of heavy quarks. The two-loop contributions to the form factor are reduced to linear combinations of master integrals, which are computed through higher orders in the parameter of dimensional regularization epsilon = (4-D)/2. Our result includes all terms of order epsilon at two loops and extends the previous literature. We apply the exponentiation of the heavy-quark form factor to derive new improved three-loop expansions in the high-energy limit. We also discuss the implications for predictions of massive n-parton amplitudes based on massless results in the limit, where the quark mass is small compared to all kinematical invariants.

  17. Nucleon form factors with 2+1 flavor dynamical domain-wall fermions

    NASA Astrophysics Data System (ADS)

    Yamazaki, Takeshi; Aoki, Yasumichi; Blum, Tom; Lin, Huey-Wen; Ohta, Shigemi; Sasaki, Shoichi; Tweedie, Robert; Zanotti, James

    2009-06-01

    We report our numerical lattice QCD calculations of the isovector nucleon form factors for the vector and axial-vector currents: the vector, induced tensor, axial-vector, and induced pseudoscalar form factors. The calculation is carried out with the gauge configurations generated with Nf=2+1 dynamical domain-wall fermions and Iwasaki gauge actions at β=2.13, corresponding to a cutoff a-1=1.73GeV, and a spatial volume of (2.7fm)3. The up and down-quark masses are varied so the pion mass lies between 0.33 and 0.67 GeV while the strange quark mass is about 12% heavier than the physical one. We calculate the form factors in the range of momentum transfers, 0.26 is required to ensure that finite-volume effects are below 1%.

  18. A Factor Analytic Study of the Coopersmith Self-Esteem Inventory Adult Short Form.

    ERIC Educational Resources Information Center

    Haines, Janet; Wilson, George V.

    1988-01-01

    A factor analysis was conducted on the Coopersmith Self-Esteem Inventory-Adult Short Form using 237 college students and 43 female office workers in Australia. Factors were found corresponding with three of the four subscales: general self, social self-peers, and home-parents (family). No factor related to the school-academic (work) subscale. (SLD)

  19. Validation of the Parenting Stress Index--Short Form with Minority Caregivers

    ERIC Educational Resources Information Center

    Lee, Sang Jung; Gopalan, Geetha; Harrington, Donna

    2016-01-01

    Objectives: There has been little examination of the structural validity of the Parenting Stress Index--Short Form (PSI-SF) for minority populations in clinical contexts in the Unites States. This study aimed to test prespecified factor structures (one-factor, two-factor, and three-factor models) of the PSI-SF. Methods: This study used…

  20. On determinant representations of scalar products and form factors in the SoV approach: the XXX case

    NASA Astrophysics Data System (ADS)

    Kitanine, N.; Maillet, J. M.; Niccoli, G.; Terras, V.

    2016-03-01

    In the present article we study the form factors of quantum integrable lattice models solvable by the separation of variables (SoVs) method. It was recently shown that these models admit universal determinant representations for the scalar products of the so-called separate states (a class which includes in particular all the eigenstates of the transfer matrix). These results permit to obtain simple expressions for the matrix elements of local operators (form factors). However, these representations have been obtained up to now only for the completely inhomogeneous versions of the lattice models considered. In this article we give a simple algebraic procedure to rewrite the scalar products (and hence the form factors) for the SoV related models as Izergin or Slavnov type determinants. This new form leads to simple expressions for the form factors in the homogeneous and thermodynamic limits. To make the presentation of our method clear, we have chosen to explain it first for the simple case of the XXX Heisenberg chain with anti-periodic boundary conditions. We would nevertheless like to stress that the approach presented in this article applies as well to a wide range of models solved in the SoV framework.

  1. Online Soil Science Lesson 3: Soil Forming Factors

    USDA-ARS?s Scientific Manuscript database

    This lesson explores the five major factors of soil formation, namely: 1) climate; 2) organisms; 3) time; 4) topography; and 5) parent material and their influence in forming soil. The distinction between active and passive factors, moisture and temperature regimes, organism and topographic influen...

  2. The Experiences in Close Relationship Scale (ECR)-short form: reliability, validity, and factor structure.

    PubMed

    Wei, Meifen; Russell, Daniel W; Mallinckrodt, Brent; Vogel, David L

    2007-04-01

    We developed a 12-item, short form of the Experiences in Close Relationship Scale (ECR; Brennan, Clark, & Shaver, 1998) across 6 studies. In Study 1, we examined the reliability and factor structure of the measure. In Studies 2 and 3, we cross-validated the reliability, factor structure, and validity of the short form measure; whereas in Study 4, we examined test-retest reliability over a 1-month period. In Studies 5 and 6, we further assessed the reliability, factor structure, and validity of the short version of the ECR when administered as a stand-alone instrument. Confirmatory factor analyses indicated that 2 factors, labeled Anxiety and Avoidance, provided a good fit to the data after removing the influence of response sets. We found validity to be equivalent for the short and the original versions of the ECR across studies. Finally, the results were comparable when we embedded the short form within the original version of the ECR and when we administered it as a stand-alone measure.

  3. Connecting the Dots: State Health Department Approaches to Addressing Shared Risk and Protective Factors Across Multiple Forms of Violence.

    PubMed

    Wilkins, Natalie; Myers, Lindsey; Kuehl, Tomei; Bauman, Alice; Hertz, Marci

    Violence takes many forms, including intimate partner violence, sexual violence, child abuse and neglect, bullying, suicidal behavior, and elder abuse and neglect. These forms of violence are interconnected and often share the same root causes. They can also co-occur together in families and communities and can happen at the same time or at different stages of life. Often, due to a variety of factors, separate, "siloed" approaches are used to address each form of violence. However, understanding and implementing approaches that prevent and address the overlapping root causes of violence (risk factors) and promote factors that increase the resilience of people and communities (protective factors) can help practitioners more effectively and efficiently use limited resources to prevent multiple forms of violence and save lives. This article presents approaches used by 2 state health departments, the Maryland Department of Health and Mental Hygiene and the Colorado Department of Public Health and Environment, to integrate a shared risk and protective factor approach into their violence prevention work and identifies key lessons learned that may serve to inform crosscutting violence prevention efforts in other states.

  4. Connecting the Dots: State Health Department Approaches to Addressing Shared Risk and Protective Factors Across Multiple Forms of Violence

    PubMed Central

    Wilkins, Natalie; Myers, Lindsey; Kuehl, Tomei; Bauman, Alice; Hertz, Marci

    2018-01-01

    Violence takes many forms, including intimate partner violence, sexual violence, child abuse and neglect, bullying, suicidal behavior, and elder abuse and neglect. These forms of violence are interconnected and often share the same root causes. They can also co-occur together in families and communities and can happen at the same time or at different stages of life. Often, due to a variety of factors, separate, “siloed” approaches are used to address each form of violence. However, understanding and implementing approaches that prevent and address the overlapping root causes of violence (risk factors) and promote factors that increase the resilience of people and communities (protective factors) can help practitioners more effectively and efficiently use limited resources to prevent multiple forms of violence and save lives. This article presents approaches used by 2 state health departments, the Maryland Department of Health and Mental Hygiene and the Colorado Department of Public Health and Environment, to integrate a shared risk and protective factor approach into their violence prevention work and identifies key lessons learned that may serve to inform crosscutting violence prevention efforts in other states. PMID:29189502

  5. The Influence of External and Internal Factors on Forming the System of Managers' Professional Development at Transnational Corporations in Poland

    ERIC Educational Resources Information Center

    Banit, Olga

    2017-01-01

    The author performs analysis of external and internal factors that influence organization of the system of Polish managers' professional development. These factors can be united into two groups. We will attribute the factors formed under the influence of external factors to the first group, to the second--the internal ones. So, due to the dynamic…

  6. Light meson form factors at high Q2 from lattice QCD

    NASA Astrophysics Data System (ADS)

    Koponen, Jonna; Zimermmane-Santos, André; Davies, Christine; Lepage, G. Peter; Lytle, Andrew

    2018-03-01

    Measurements and theoretical calculations of meson form factors are essential for our understanding of internal hadron structure and QCD, the dynamics that bind the quarks in hadrons. The pion electromagnetic form factor has been measured at small space-like momentum transfer |q2| < 0.3 GeV2 by pion scattering from atomic electrons and at values up to 2.5 GeV2 by scattering electrons from the pion cloud around a proton. On the other hand, in the limit of very large (or infinite) Q2 = -q2, perturbation theory is applicable. This leaves a gap in the intermediate Q2 where the form factors are not known. As a part of their 12 GeV upgrade Jefferson Lab will measure pion and kaon form factors in this intermediate region, up to Q2 of 6 GeV2. This is then an ideal opportunity for lattice QCD to make an accurate prediction ahead of the experimental results. Lattice QCD provides a from-first-principles approach to calculate form factors, and the challenge here is to control the statistical and systematic uncertainties as errors grow when going to higher Q2 values. Here we report on a calculation that tests the method using an ηs meson, a 'heavy pion' made of strange quarks, and also present preliminary results for kaon and pion form factors. We use the nf = 2 + 1 + 1 ensembles made by the MILC collaboration and Highly Improved Staggered Quarks, which allows us to obtain high statistics. The HISQ action is also designed to have small dicretisation errors. Using several light quark masses and lattice spacings allows us to control the chiral and continuum extrapolation and keep systematic errors in check. Warning, no authors found for 2018EPJWC.17506016.

  7. $$|V_{ub}|$$ from $$B\\to\\pi\\ell\

    DOE PAGES

    Bailey, Jon A.; et al.

    2015-07-23

    We present a lattice-QCD calculation of the B → πℓν semileptonic form factors and a new determination of the CKM matrix element |V ub|. We use the MILC asqtad (2+1)-flavor lattice configurations at four lattice spacings and light-quark masses down to 1/20 of the physical strange-quark mass. We extrapolate the lattice form factors to the continuum using staggered chiral perturbation theory in the hard-pion and SU(2) limits. We employ a model-independent z parametrization to extrapolate our lattice form factors from large-recoil momentum to the full kinematic range. We introduce a new functional method to propagate information from the chiral-continuum extrapolationmore » to the z expansion. We present our results together with a complete systematic error budget, including a covariance matrix to enable the combination of our form factors with other lattice-QCD and experimental results. To obtain |V ub|, we simultaneously fit the experimental data for the B → πℓν differential decay rate obtained by the BABAR and Belle collaborations together with our lattice form-factor results. We find |V ub|=(3.72±0.16) × 10 –3, where the error is from the combined fit to lattice plus experiments and includes all sources of uncertainty. Our form-factor results bring the QCD error on |V ub| to the same level as the experimental error. We also provide results for the B → πℓν vector and scalar form factors obtained from the combined lattice and experiment fit, which are more precisely determined than from our lattice-QCD calculation alone. Lastly, these results can be used in other phenomenological applications and to test other approaches to QCD.« less

  8. Elastic and transition form factors of the Δ(1232)

    DOE PAGES

    Segovia, Jorge; Chen, Chen; Cloet, Ian C.; ...

    2013-12-10

    Predictions obtained with a confining, symmetry-preserving treatment of a vector Ⓧ vector contact interaction at leading-order in a widely used truncation of QCD’s Dyson–Schwinger equations are presented for Δ and Ω baryon elastic form factors and the γN → Δ transition form factors. This simple framework produces results that are practically indistinguishable from the best otherwise available, an outcome which highlights that the key to describing many features of baryons and unifying them with the properties of mesons is a veracious expression of dynamical chiral symmetry breaking in the hadron bound-state problem. The following specific results are of particular interest.more » The Δ elastic form factors are very sensitive to m Δ. Hence, given that the parameters which define extant simulations of lattice-regularised QCD produce Δ-resonance masses that are very large, the form factors obtained therewith are a poor guide to properties of the Δ(1232). Considering the Δ-baryon’s quadrupole moment, whilst all computations produce a negative value, the conflict between theoretical predictions entails that it is currently impossible to reach a sound conclusion on the nature of the Δ-baryon’s deformation in the infinite momentum frame. Furthermore, results for analogous properties of the Ω baryon are less contentious. In connection with the N → Δ transition, the Ash-convention magnetic transition form factor falls faster than the neutron’s magnetic form factor and nonzero values for the associated quadrupole ratios reveal the impact of quark orbital angular momentum within the nucleon and Δ; and, furthermore, these quadrupole ratios do slowly approach their anticipated asymptotic limits.« less

  9. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bailey, Jon A.; et al.

    We present a lattice-QCD calculation of the B → πℓν semileptonic form factors and a new determination of the CKM matrix element |V ub|. We use the MILC asqtad (2+1)-flavor lattice configurations at four lattice spacings and light-quark masses down to 1/20 of the physical strange-quark mass. We extrapolate the lattice form factors to the continuum using staggered chiral perturbation theory in the hard-pion and SU(2) limits. We employ a model-independent z parametrization to extrapolate our lattice form factors from large-recoil momentum to the full kinematic range. We introduce a new functional method to propagate information from the chiral-continuum extrapolationmore » to the z expansion. We present our results together with a complete systematic error budget, including a covariance matrix to enable the combination of our form factors with other lattice-QCD and experimental results. To obtain |V ub|, we simultaneously fit the experimental data for the B → πℓν differential decay rate obtained by the BABAR and Belle collaborations together with our lattice form-factor results. We find |V ub|=(3.72±0.16) × 10 –3, where the error is from the combined fit to lattice plus experiments and includes all sources of uncertainty. Our form-factor results bring the QCD error on |V ub| to the same level as the experimental error. We also provide results for the B → πℓν vector and scalar form factors obtained from the combined lattice and experiment fit, which are more precisely determined than from our lattice-QCD calculation alone. Lastly, these results can be used in other phenomenological applications and to test other approaches to QCD.« less

  10. Urban form and psychosocial factors: do they interact for leisure-time walking?

    PubMed

    Beenackers, Mariëlle A; Kamphuis, Carlijn B M; Prins, Richard G; Mackenbach, Johan P; Burdorf, Alex; van Lenthe, Frank J

    2014-02-01

    This cross-sectional study uses an adaptation of a social-ecological model on the hierarchy of walking needs to explore direct associations and interactions of urban-form characteristics and individual psychosocial factors for leisure-time walking. Questionnaire data (n = 736) from adults (25-74 yr) and systematic field observations within 14 neighborhoods in Eindhoven (the Netherlands) were used. Multilevel logistic regression models were used to relate the urban-form characteristics (accessibility, safety, comfort, and pleasurability) and individual psychosocial factors (attitude, self-efficacy, social influence, and intention) to two definitions of leisure-time walking, that is, any leisure-time walking and sufficient leisure-time walking according to the Dutch physical activity norm and to explore their interactions. Leisure-time walking was associated with psychosocial factors but not with characteristics of the urban environment. For sufficient leisure-time walking, interactions between attitude and several urban-form characteristics were found, indicating that positive urban-form characteristics contributed toward leisure-time walking only in residents with a less positive attitude toward physical activity. In contrast, living in a neighborhood that was accessible for walking was stronger associated with leisure-time walking among residents who experienced a positive social influence to engage in physical activity compared with those who reported less social influence. This study showed some evidence for an interaction between the neighborhood environment and the individual psychosocial factors in explaining leisure-time walking. The specific mechanism of interaction may depend on the specific combination of psychosocial factor and environmental factor. The lack of association between urban form and leisure-time walking could be partly due to the little variation in urban-form characteristics between neighborhoods.

  11. 78 FR 2483 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-11

    ... Structured Settlement Factoring Transactions. Form: 8876. Abstract: Form 8876 is used to report and pay the 40 percent excise tax imposed under Sec. 5891 on the factoring discount of a structured settlement factoring transaction. Affected Public: Private Sector: Businesses or other for-profits. Estimated Total...

  12. Nuclear longitudinal form factors for axially deformed charge distributions expanded by nonorthogonal basis functions

    NASA Astrophysics Data System (ADS)

    Liu, Jian; Zhang, Jinjuan; Xu, Chang; Ren, Zhongzhou

    2017-05-01

    In this paper, the nuclear longitudinal form factors are systematically studied from the intrinsic charge multipoles. For axially deformed nuclei, two different types of density profiles are used to describe their charge distributions. For the same charge distributions expanded with different basis functions, the corresponding longitudinal form factors are derived and compared with each other. Results show the multipoles Cλ of longitudinal form factors are independent of the basis functions of charge distributions. Further numerical calculations of longitudinal form factors of 12C indicates that the C 0 multipole reflects the contributions of spherical components of all nonorthogonal basis functions. For deformed nuclei, their charge RMS radii can also be determined accurately by the C 0 measurement. The studies in this paper examine the model-independent properties of electron scattering, which are useful for interpreting electron scattering experiments on exotic deformed nuclei. Supported by National Natural Science Foundation of China (11505292, 11175085, 11575082, 11235001, 11275138, and 11447226), by Shandong Provincial Natural Science Foundation, China (BS2014SF007), Fundamental Research Funds for Central Universities (15CX02072A).

  13. Electromagnetic Transition Form Factor of the η meson with WASA-at-COSY

    NASA Astrophysics Data System (ADS)

    Goswami, A.

    2016-11-01

    In this work we present a study of the Dalitz decay η → γe+e-. The aim of this work is to measure the transition form factor of the η meson. The transition form factor of the η meson describes the electromagnetic structure of the meson. The study of the Dalitz decay helps to calculate the transition form factor of the η meson. When a particle is point-like it's decay rate can be calculated within QED. However, the complex structure of the meson modifies its decay rate. The transition form factor is determined by comparing the lepton-antilepton invariant mass distribution with QED. For this study data on proton-proton reaction at a beam energy of 1.4 GeV has been collected with WASA-at-COSY detector at Forschungszentrum Juelich, Germany. In the higher invariant mass region recent theoretical calculations slightly deviate from the fit to the data. We expect better results in the higher invariant mass region than previous measurements. The preliminary results of the analysis will be presented.

  14. A projection operator method for the analysis of magnetic neutron form factors

    NASA Astrophysics Data System (ADS)

    Kaprzyk, S.; Van Laar, B.; Maniawski, F.

    1981-03-01

    A set of projection operators in matrix form has been derived on the basis of decomposition of the spin density into a series of fully symmetrized cubic harmonics. This set of projection operators allows a formulation of the Fourier analysis of magnetic form factors in a convenient way. The presented method is capable of checking the validity of various theoretical models used for spin density analysis up to now. The general formalism is worked out in explicit form for the fcc and bcc structures and deals with that part of spin density which is contained within the sphere inscribed in the Wigner-Seitz cell. This projection operator method has been tested on the magnetic form factors of nickel and iron.

  15. Normalization Of Thermal-Radiation Form-Factor Matrix

    NASA Technical Reports Server (NTRS)

    Tsuyuki, Glenn T.

    1994-01-01

    Report describes algorithm that adjusts form-factor matrix in TRASYS computer program, which calculates intraspacecraft radiative interchange among various surfaces and environmental heat loading from sources such as sun.

  16. Strange and Charge Symmetry Violating Electromagnetic Form Factors of the Nucleon

    NASA Astrophysics Data System (ADS)

    Shanahan, P. E.

    We summarise recent work based on lattice QCD simulations of the electromagnetic form factors of the octet baryons from the CSSM/QCDSF/UKQCD collaborations. After an analysis of the simulation results using techniques to approach the infinite volume limit and the physical pseudoscalar masses at non-zero momentum transfer, the extrapolated proton and neutron form factors are found to be in excellent agreement with those extracted from experiment. Given the success of these calculations, we describe how the strange electromagnetic form factors may be estimated from these results under the same assumption of charge symmetry used in experimental determinations of those quantities. Motivated by the necessity of that assumption, we explore a method for determining the size of charge symmetry breaking effects using the same lattice results.

  17. Holographic estimate of the meson cloud contribution to nucleon axial form factor

    NASA Astrophysics Data System (ADS)

    Ramalho, G.

    2018-04-01

    We use light-front holography to estimate the valence quark and the meson cloud contributions to the nucleon axial form factor. The free couplings of the holographic model are determined by the empirical data and by the information extracted from lattice QCD. The holographic model provides a good description of the empirical data when we consider a meson cloud mixture of about 30% in the physical nucleon state. The estimate of the valence quark contribution to the nucleon axial form factor compares well with the lattice QCD data for small pion masses. Our estimate of the meson cloud contribution to the nucleon axial form factor has a slower falloff with the square momentum transfer compared to typical estimates from quark models with meson cloud dressing.

  18. Nucleon form factors from quenched lattice QCD with domain wall fermions

    NASA Astrophysics Data System (ADS)

    Sasaki, Shoichi; Yamazaki, Takeshi

    2008-07-01

    We present a quenched lattice calculation of the weak nucleon form factors: vector [FV(q2)], induced tensor [FT(q2)], axial vector [FA(q2)] and induced pseudoscalar [FP(q2)] form factors. Our simulations are performed on three different lattice sizes L3×T=243×32, 163×32, and 123×32 with a lattice cutoff of a-1≈1.3GeV and light quark masses down to about 1/4 the strange quark mass (mπ≈390MeV) using a combination of the DBW2 gauge action and domain wall fermions. The physical volume of our largest lattice is about (3.6fm)3, where the finite volume effects on form factors become negligible and the lower momentum transfers (q2≈0.1GeV2) are accessible. The q2 dependences of form factors in the low q2 region are examined. It is found that the vector, induced tensor, and axial-vector form factors are well described by the dipole form, while the induced pseudoscalar form factor is consistent with pion-pole dominance. We obtain the ratio of axial to vector coupling gA/gV=FA(0)/FV(0)=1.219(38) and the pseudoscalar coupling gP=mμFP(0.88mμ2)=8.15(54), where the errors are statistical errors only. These values agree with experimental values from neutron β decay and muon capture on the proton. However, the root mean-squared radii of the vector, induced tensor, and axial vector underestimate the known experimental values by about 20%. We also calculate the pseudoscalar nucleon matrix element in order to verify the axial Ward-Takahashi identity in terms of the nucleon matrix elements, which may be called as the generalized Goldberger-Treiman relation.

  19. Multilevel Confirmatory Factor Analysis of the Teacher My Class Inventory-Short Form

    ERIC Educational Resources Information Center

    Villares, Elizabeth; Mariani, Melissa; Sink, Christopher A.; Colvin, Kimberly

    2016-01-01

    Researchers analyzed data from elementary teachers (N = 233) to further establish the psychometric soundness of the Teacher My Class Inventory-Short Form. Supporting previous psychometric research, confirmatory factor analyses findings supported the factorial validity of the hypothesized five-factor solution. Internal reliability estimates were…

  20. Psychometric properties of Positive and Negative Affect Schedule (PANAS) original and short forms in an African American community sample.

    PubMed

    Merz, Erin L; Malcarne, Vanessa L; Roesch, Scott C; Ko, Celine M; Emerson, Marc; Roma, Vincenzo G; Sadler, Georgia Robins

    2013-12-01

    The Positive and Negative Affect Schedule (PANAS) has been widely used as a self-report measure of affect in community and clinical contexts. However, evaluations of the psychometric properties of PANAS scores have been limited in diverse ethnic groups. Several short forms of the PANAS have also been proposed, but very little is known about the psychometric properties of these versions. The present study investigated the psychometric properties, including the factor structure of the original PANAS and two short forms in an African American community sample (N=239). Descriptive, internal consistency reliability, factorial validity, and measurement invariance analyses were conducted. All PANAS subscales from the original and short forms had adequate internal consistency. For the original PANAS, the model specifying three correlated factors (Positive Affect, Afraid, Upset) with correlated uniquenesses from redundant items provided the best fit to the data. However, the two-factor model (Positive Affect, Negative Affect) with correlated uniquenesses was also supported. For both short forms, the two-factor model with correlated uniquenesses fit the data best. Factors from all forms were generally invariant across age and gender, although there was some minor invariance at the item level. Participants were from a limited geographic area and one ethnic group. Indicators of anxiety, depression, and cultural characteristics were not measured. The factor structure was replicated, suggesting no immediate concerns regarding the valid interpretation of PANAS scores. The results support the reliability and validity of the PANAS and its short forms for use among African Americans. © 2013 Elsevier B.V. All rights reserved.

  1. Gravitational form factors and decoupling in 2D

    NASA Astrophysics Data System (ADS)

    Ribeiro, Tiago G.; Shapiro, Ilya L.; Zanusso, Omar

    2018-07-01

    We calculate and analyse non-local gravitational form factors induced by quantum matter fields in curved two-dimensional space. The calculations are performed for scalars, spinors and massive vectors by means of the covariant heat kernel method up to the second order in the curvature and confirmed using Feynman diagrams. The analysis of the ultraviolet (UV) limit reveals a generalized "running" form of the Polyakov action for a nonminimal scalar field and the usual Polyakov action in the conformally invariant cases. In the infrared (IR) we establish the gravitational decoupling theorem, which can be seen directly from the form factors or from the physical beta function for fields of any spin.

  2. Towards a dispersive determination of the pion transition form factor

    NASA Astrophysics Data System (ADS)

    Leupold, Stefan; Hoferichter, Martin; Kubis, Bastian; Niecknig, Franz; Schneider, Sebastian P.

    2018-01-01

    We start with a brief motivation why the pion transition form factor is interesting and, in particular, how it is related to the high-precision standard-model calculation of the gyromagnetic ratio of the muon. Then we report on the current status of our ongoing project to calculate the pion transition form factor using dispersion theory. Finally we present and discuss a wish list of experimental data that would help to improve the input for our calculations and/or to cross-check our results.

  3. Analysis of the J /ψ →π0γ* transition form factor

    NASA Astrophysics Data System (ADS)

    Kubis, Bastian; Niecknig, Franz

    2015-02-01

    In view of the first measurement of the branching fraction for J /ψ →π0e+e- by the BESIII collaboration, we analyze what can be learned on the corresponding transition form factor using dispersion theory. We show that light-quark degrees of freedom dominate the spectral function, in particular two-pion intermediate states. Estimating the effects of multipion states as well as charmonium, we arrive at a prediction for the complete form factor that should be scrutinized experimentally in the future.

  4. Similarity of urinary risk factors among stone-forming patients in five regions of the United States

    NASA Technical Reports Server (NTRS)

    Harvey, J. A.; Hill, K. D.; Pak, C. Y.

    1990-01-01

    Study Objective: To compare urinary biochemical risk factors among stone-forming patients in the Southeast (SE) or "stone belt" versus four other regions of the United States. Design: Prospective biochemical survey for regional comparisons. Setting: Referral-based nephrolithiasis clinics, urologists, nephrologists, and family practitioners. Patients: Consecutive sample of 3473 stone-forming patients who submitted 24-hour urine collections for biochemical analyses of stone-forming risk factors. Interventions: None. Subjects taking medication known to interfere with stone-forming risk factors were deleted from the final data compilation. Measurements and Main Results: Overall, the mean values for each urinary parameter spanned a narrow range without significant difference between the five regions. Among "metabolic" factors, 40% in the SE had hypercalciuria (> 6.25 mmol/d), compared to 35%-43% in other regions, and hyperuricosuria (> 4.2 mmol/d) was found in 16% in the SE versus 17%-19% elsewhere. Among "environmental" factors, low urine volume ( < 2 L/d) was found in 77% patients in the SE compared to 69%-78% elsewhere, and high sodium was encountered in 27% in the SE versus 24%-29% elsewhere. No differences were noted in occurrence of other abnormal risk factors: hyperoxaluria, hypocitraturia, low pH, high sulfate, high phosphorus, or low magnesium. Conclusions: Despite expected regional differences in nutritional and environmental influences, the results of this study showed a striking similarity in urinary biochemical risk factor profiles of stone-formers in all five regions of the United States.

  5. Nucleon and Elastic and Transition Form Factors

    NASA Astrophysics Data System (ADS)

    Segovia, Jorge; Cloët, Ian C.; Roberts, Craig D.; Schmidt, Sebastian M.

    2014-12-01

    We present a unified study of nucleon and elastic and transition form factors, and compare predictions made using a framework built upon a Faddeev equation kernel and interaction vertices that possess QCD-like momentum dependence with results obtained using a symmetry-preserving treatment of a vector vector contact-interaction. The comparison emphasises that experiments are sensitive to the momentum dependence of the running couplings and masses in the strong interaction sector of the Standard Model and highlights that the key to describing hadron properties is a veracious expression of dynamical chiral symmetry breaking in the bound-state problem. Amongst the results we describe, the following are of particular interest: possesses a zero at Q 2 = 9.5 GeV2; any change in the interaction which shifts a zero in the proton ratio to larger Q 2 relocates a zero in to smaller Q 2; there is likely a value of momentum transfer above which ; and the presence of strong diquark correlations within the nucleon is sufficient to understand empirical extractions of the flavour-separated form factors. Regarding the -baryon, we find that, inter alia: the electric monopole form factor exhibits a zero; the electric quadrupole form factor is negative, large in magnitude, and sensitive to the nature and strength of correlations in the Faddeev amplitude; and the magnetic octupole form factor is negative so long as rest-frame P- and D-wave correlations are included. In connection with the transition, the momentum-dependence of the magnetic transition form factor, , matches that of once the momentum transfer is high enough to pierce the meson-cloud; and the electric quadrupole ratio is a keen measure of diquark and orbital angular momentum correlations, the zero in which is obscured by meson-cloud effects on the domain currently accessible to experiment. Importantly, within each framework, identical propagators and vertices are sufficient to describe all properties discussed herein. Our analysis and predictions should therefore serve as motivation for measurement of elastic and transition form factors involving the nucleon and its resonances at high photon virtualities using modern electron-beam facilities.

  6. Extraction of the neutron electric form factor from measurements of inclusive double spin asymmetries

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sulkosky, V.; Jin, G.; Long, E.

    Background: Measurements of the neutron charge form factor, Gmore » $$n\\atop{E}$$, are challenging because the neutron has no net charge. Additionally, measurements of the neutron form factors must use nuclear targets which require accurately accounting for nuclear effects. Extracting G$$n\\atop{E}$$ with different targets and techniques provides an important test of our handling of these effects. Purpose: The goal of the measurement was to use an inclusive asymmetry measurement technique to extract the neutron charge form factor at a four-momentum transfer of 1 (GeV/c) 2. This technique has very different systematic uncertainties than traditional exclusive measurements and thus serves as an independent check of whether nuclear effects have been taken into account correctly. Method: The inclusive quasielastic reaction 3$$→\\atop{He}$$ ($$→\\atop{e}$$, e') was measured at Jefferson Laboratory. The neutron electric form factor, G$$n\\atop{E}$$, was extracted at Q 2 = 0.98 ( GeV/c) 2 from ratios of electron-polarization asymmetries measured for two orthogonal target spin orientations. This Q 2 is high enough that the sensitivity to G$$n\\atop{E}$$ is not overwhelmed by the neutron magnetic contribution, and yet low enough that explicit neutron detection is not required to suppress pion production. Results: The neutron electric form factor, G$$n\\atop{E}$$, was determined to be 0.0414 ± 0.0077 ( stat ) ± 0.0022 ( syst ), providing the first high-precision inclusive extraction of the neutron's charge form factor. In conclusion: The use of the inclusive quasielastic 3$$→\\atop{He}$$ ($$→\\atop{e}$$, e') with a four-momentum transfer near 1 (GeV/c) 2 has been used to provide a unique measurement of G$$n\\atop{E}$$. This new result provides a systematically independent validation of the exclusive extraction technique results and implies that the nuclear corrections are understood. This is contrary to the proton form factor where asymmetry and differential cross section measurements have been shown to have large systematic differences.« less

  7. Extraction of the neutron electric form factor from measurements of inclusive double spin asymmetries

    DOE PAGES

    Sulkosky, V.; Jin, G.; Long, E.; ...

    2017-12-26

    Background: Measurements of the neutron charge form factor, Gmore » $$n\\atop{E}$$, are challenging because the neutron has no net charge. Additionally, measurements of the neutron form factors must use nuclear targets which require accurately accounting for nuclear effects. Extracting G$$n\\atop{E}$$ with different targets and techniques provides an important test of our handling of these effects. Purpose: The goal of the measurement was to use an inclusive asymmetry measurement technique to extract the neutron charge form factor at a four-momentum transfer of 1 (GeV/c) 2. This technique has very different systematic uncertainties than traditional exclusive measurements and thus serves as an independent check of whether nuclear effects have been taken into account correctly. Method: The inclusive quasielastic reaction 3$$→\\atop{He}$$ ($$→\\atop{e}$$, e') was measured at Jefferson Laboratory. The neutron electric form factor, G$$n\\atop{E}$$, was extracted at Q 2 = 0.98 ( GeV/c) 2 from ratios of electron-polarization asymmetries measured for two orthogonal target spin orientations. This Q 2 is high enough that the sensitivity to G$$n\\atop{E}$$ is not overwhelmed by the neutron magnetic contribution, and yet low enough that explicit neutron detection is not required to suppress pion production. Results: The neutron electric form factor, G$$n\\atop{E}$$, was determined to be 0.0414 ± 0.0077 ( stat ) ± 0.0022 ( syst ), providing the first high-precision inclusive extraction of the neutron's charge form factor. In conclusion: The use of the inclusive quasielastic 3$$→\\atop{He}$$ ($$→\\atop{e}$$, e') with a four-momentum transfer near 1 (GeV/c) 2 has been used to provide a unique measurement of G$$n\\atop{E}$$. This new result provides a systematically independent validation of the exclusive extraction technique results and implies that the nuclear corrections are understood. This is contrary to the proton form factor where asymmetry and differential cross section measurements have been shown to have large systematic differences.« less

  8. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Almus, F.E.; Rao, L.V.; Fleck, R.A.

    An umbilical vein model was designed in which washed vein segments are filled with a reaction mixture containing factor VIIa, Ca(+)+, and a substrate, either 3H-factor IX or 3H-factor X. The vein wall provides the tissue factor (TF) for factor VIIa/TF complexes that activate the substrates as measured by activation peptide release. The model was developed to study TF induced on venous endothelium in situ. However, unlike previous studies with TF expressed on cultured umbilical vein endothelial cells, factors IX and X were activated without first having to expose the vein wall to a perturbing stimulus. Histologic studies revealed thatmore » washing the vein and mixing the reaction mixture before subsampling had disrupted the endothelium. Immunostaining with anti-TF antibodies revealed no staining of endothelium but intense staining in extensions of Wharton's jelly penetrating fenestrations of the muscularis media of the vein. Thus, the model provided data on factor VIIa/TF formed, not on endothelium, but within the mucoid connective tissue of Wharton's jelly. It is known that factor VIIa/TF formed with TF in suspension or with TF expressed on the surface of cultured cells activates factor X more rapidly than factor IX. In contrast, in the umbilical vein model, when each substrate was present in an 88 nmol/L concentration, factors IX and X were activated at equivalent rates (mean activation rate for factor IX, 18.8 +/- 3.6 nmol/L/h; for factor X, 17.8 +/- 2.9 nmol/L/h; n = 9 paired vein segments). These data strengthen the evidence that factor VIIa/TF activation of factor IX represents a key initial reaction of coagulation in tissues. These results also show that data obtained with factor VIIa/TF complexes formed on the surface of cultured cells need not hold for factor VIIa/TF complexes formed in extracellular matrix.« less

  9. Thermal form-factor approach to dynamical correlation functions of integrable lattice models

    NASA Astrophysics Data System (ADS)

    Göhmann, Frank; Karbach, Michael; Klümper, Andreas; Kozlowski, Karol K.; Suzuki, Junji

    2017-11-01

    We propose a method for calculating dynamical correlation functions at finite temperature in integrable lattice models of Yang-Baxter type. The method is based on an expansion of the correlation functions as a series over matrix elements of a time-dependent quantum transfer matrix rather than the Hamiltonian. In the infinite Trotter-number limit the matrix elements become time independent and turn into the thermal form factors studied previously in the context of static correlation functions. We make this explicit with the example of the XXZ model. We show how the form factors can be summed utilizing certain auxiliary functions solving finite sets of nonlinear integral equations. The case of the XX model is worked out in more detail leading to a novel form-factor series representation of the dynamical transverse two-point function.

  10. An Investigation of the Factor Structure and Convergent and Discriminant Validity of the Five-Factor Model Rating Form

    ERIC Educational Resources Information Center

    Samuel, Douglas B.; Mullins-Sweatt, Stephanie N.; Widiger, Thomas A.

    2013-01-01

    The Five-Factor Model Rating Form (FFMRF) is a one-page measure designed to provide an efficient assessment of the higher order domains of the Five Factor Model (FFM) as well as the more specific, lower order facets proposed by McCrae and Costa. Although previous research has suggested that the FFMRF's assessment of the lower order facets converge…

  11. Determination of Transverse Charge Density from Kaon Form Factor Data

    NASA Astrophysics Data System (ADS)

    Mejia-Ott, Johann; Horn, Tanja; Pegg, Ian; Mecholski, Nicholas; Carmignotto, Marco; Ali, Salina

    2016-09-01

    At the level of nucleons making up atomic nuclei, among subatomic particles made up of quarks, K-mesons or kaons represent the most simple hadronic system including the heavier strange quark, having a relatively elementary bound state of a quark and an anti-quark as its valence structure. Its electromagnetic structure is then parametrized by a single, dimensionless quantity known as the form factor, the two-dimensional Fourier transform of which yields the quantity of transverse charge density. Transverse charge density, in turn, provides a needed framework for the interpretation of form factors in terms of physical charge and magnetization, both with respect to the propagation of a fast-moving nucleon. To this is added the value of strange quarks in ultimately presenting a universal, process-independent description of nucleons, further augmenting the importance of studying the kaon's internal structure. The pressing character of such research questions directs the present paper, describing the first extraction of transverse charge density from electromagnetic kaon form factor data. The extraction is notably extended to form factor data at recently acquired higher energy levels, whose evaluation could permit more complete phenomenological models for kaon behavior to be proposed. This work was supported in part by NSF Grant PHY-1306227.

  12. Features and flaws of a contact interaction treatment of the kaon

    NASA Astrophysics Data System (ADS)

    Chen, Chen; Chang, Lei; Roberts, Craig D.; Schmidt, Sebastian M.; Wan, Shaolong; Wilson, David J.

    2013-04-01

    Elastic and semileptonic transition form factors for the kaon and pion are calculated using the leading order in a global-symmetry-preserving truncation of the Dyson-Schwinger equations and a momentum-independent form for the associated kernels in the gap and Bethe-Salpeter equations. The computed form factors are compared both with those obtained using the same truncation but an interaction that preserves the one-loop renormalization-group behavior of QCD and with data. The comparisons show that in connection with observables revealed by probes with |Q2|≲M2, where M≈0.4GeV is an infrared value of the dressed-quark mass, results obtained using a symmetry-preserving regularization of the contact interaction are not realistically distinguishable from those produced by more sophisticated kernels, and available data on kaon form factors do not extend into the domain whereupon one could distinguish among the interactions. The situation differs if one includes the domain Q2>M2. Thereupon, a fully consistent treatment of the contact interaction produces form factors that are typically harder than those obtained with QCD renormalization-group-improved kernels. Among other things also described are a Ward identity for the inhomogeneous scalar vertex, similarity between the charge distribution of a dressed u quark in the K+ and that of the dressed u quark in the π+, and reflections upon the point whereat one might begin to see perturbative behavior in the pion form factor. Interpolations of the form factors are provided, which should assist in working to chart the interaction between light quarks by explicating the impact on hadron properties of differing assumptions about the behavior of the Bethe-Salpeter kernel.

  13. Constructing Nucleon Operators on a Lattice for Form Factors with High Momentum Transfer

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Syritsyn, Sergey; Gambhir, Arjun S.; Musch, Bernhard U.

    We present preliminary results of computing nucleon form factor at high momentum transfer using the 'boosted' or 'momentum' smearing. We use gauge configurations generated with N f = 2 + 1dynamical Wilson-clover fermions and study the connected as well as disconnected contributions to the nucleon form factors. Our initial results indicate that boosted smearing helps to improve the signal for nucleon correlators at high momentum. However, we also find evidence for large excited state contributions, which will likely require variational analysis to isolate the boosted nucleon ground state.

  14. D meson semileptonic form factors in Nf = 3 QCD with Möbius domain-wall quarks

    NASA Astrophysics Data System (ADS)

    Kaneko, Takashi; Colquhoun, Brian; Fukaya, Hidenori; Hashimoto, Shoji

    2018-03-01

    e present our calculation of D → π and D → K semileptonic form factors in Nf = 2 + 1 lattice QCD. We simulate three lattice cutoffs a-1 ≃ 2.5, 3.6 and 4.5 GeV with pion masses as low as 230 MeV. The Möbius domain-wall action is employed for both light and charm quarks. We present our results for the vector and scalar form factors and discuss their dependence on the lattice spacing, light quark masses and momentum transfer.

  15. Timelike pion form factor in lattice QCD

    NASA Astrophysics Data System (ADS)

    Feng, Xu; Aoki, Sinya; Hashimoto, Shoji; Kaneko, Takashi

    2015-03-01

    We perform a nonperturbative lattice calculation of the complex phase and modulus of the pion form factor in the timelike momentum region using the finite-volume technique. We use two ensembles of 2 +1 -flavor overlap fermions at pion masses mπ=380 and 290 MeV. By calculating the I =1 correlators in the center-of-mass and three moving frames, we obtain the form factor at ten different values of the timelike momentum transfer around the vector resonance. We compare the results with the phenomenological model of Gounaris-Sakurai and its variant.

  16. Factor Structure and Psychometric Properties of the Young Schema Questionnaire (Short Form) in Chinese Undergraduate Students

    ERIC Educational Resources Information Center

    Cui, Lixia; Lin, Wenwen; Oei, Tian P. S.

    2011-01-01

    This study investigated cross-cultural differences in the factor structure and psychometric properties of the Young Schema Questionnaire (short form; YSQ-SF). The participants were 712 Chinese undergraduate students. The total sample was randomly divided into two sub-samples. Exploratory Factor Analysis (EFA) was conducted on questionnaire results…

  17. Optical flashes from internal pairs formed in gamma-ray burst afterglows

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Panaitescu, A.

    We develop a numerical formalism for calculating the distribution with energy of the (internal) pairs formed in a relativistic source from unscattered MeV–TeV photons. For gamma-ray burst (GRB) afterglows, this formalism is more suitable if the relativistic reverse shock that energizes the ejecta is the source of the GeV photons. The number of pairs formed is set by the source GeV output (calculated from the Fermi-LAT fluence), the unknown source Lorentz factor, and the unmeasured peak energy of the LAT spectral component. We show synchrotron and inverse-Compton light curves expected from pairs formed in the shocked medium and identify some criteria for testing a pair origin of GRB optical counterparts. Pairs formed in bright LAT afterglows with a Lorentz factor in the few hundreds may produce bright optical counterparts (more » $$R\\lt 10$$) lasting for up to one hundred seconds. As a result, the number of internal pairs formed from unscattered seed photons decreases very strongly with the source Lorentz factor, thus bright GRB optical counterparts cannot arise from internal pairs if the afterglow Lorentz factor is above several hundreds.« less

  18. Optical flashes from internal pairs formed in gamma-ray burst afterglows

    DOE PAGES

    Panaitescu, A.

    2015-06-09

    We develop a numerical formalism for calculating the distribution with energy of the (internal) pairs formed in a relativistic source from unscattered MeV–TeV photons. For gamma-ray burst (GRB) afterglows, this formalism is more suitable if the relativistic reverse shock that energizes the ejecta is the source of the GeV photons. The number of pairs formed is set by the source GeV output (calculated from the Fermi-LAT fluence), the unknown source Lorentz factor, and the unmeasured peak energy of the LAT spectral component. We show synchrotron and inverse-Compton light curves expected from pairs formed in the shocked medium and identify some criteria for testing a pair origin of GRB optical counterparts. Pairs formed in bright LAT afterglows with a Lorentz factor in the few hundreds may produce bright optical counterparts (more » $$R\\lt 10$$) lasting for up to one hundred seconds. As a result, the number of internal pairs formed from unscattered seed photons decreases very strongly with the source Lorentz factor, thus bright GRB optical counterparts cannot arise from internal pairs if the afterglow Lorentz factor is above several hundreds.« less

  19. JLab Measurements of the He 3 Form Factors at Large Momentum Transfers

    DOE PAGES

    Camsonne, A.; Katramatou, A. T.; Olson, M.; ...

    2017-10-19

    The charge and magnetic form factors, F C and F M, respectively, of 3He are extracted in the kinematic range 25 fm –2 ≤ Q 2 ≤ 61 fm –2 from elastic electron scattering by detecting 3He recoil nuclei and scattered electrons in coincidence with the two High Resolution Spectrometers of the Hall A Facility at Jefferson Lab. The measurements find evidence for the existence of a second diffraction minimum for the magnetic form factor at Q 2 = 49.3 fm –2 and for the charge form factor at Q 2 = 62.0 fm –2. Both minima are predicted tomore » exist in the Q 2 range accessible by this Jefferson Lab experiment. Here, the data are in qualitative agreement with theoretical calculations based on realistic interactions and accurate methods to solve the three-body nuclear problem.« less

  20. Feasibility studies of time-like proton electromagnetic form factors at $$\\overline{\\rm P}$$ANDA at FAIR

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Singh, B.; Erni, W.; Krusche, B.

    Simulation results for future measurements of electromagnetic proton form factors atmore » $$\\overline{\\rm P}$$ANDA (FAIR) within the PandaRoot software framework are reported. The statistical precision with which the proton form factors can be determined is estimated. The signal channel p¯p → e +e – is studied on the basis of two different but consistent procedures. The suppression of the main background channel, i.e. p¯p → π +π –, is studied. Furthermore, the background versus signal efficiency, statistical and systematical uncertainties on the extracted proton form factors are evaluated using two different procedures. The results are consistent with those of a previous simulation study using an older, simplified framework. Furthermore, a slightly better precision is achieved in the PandaRoot study in a large range of momentum transfer, assuming the nominal beam conditions and detector performance.« less

  1. JLab Measurements of the He 3 Form Factors at Large Momentum Transfers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Camsonne, A.; Katramatou, A. T.; Olson, M.

    The charge and magnetic form factors, F C and F M, respectively, of 3He are extracted in the kinematic range 25 fm –2 ≤ Q 2 ≤ 61 fm –2 from elastic electron scattering by detecting 3He recoil nuclei and scattered electrons in coincidence with the two High Resolution Spectrometers of the Hall A Facility at Jefferson Lab. The measurements find evidence for the existence of a second diffraction minimum for the magnetic form factor at Q 2 = 49.3 fm –2 and for the charge form factor at Q 2 = 62.0 fm –2. Both minima are predicted tomore » exist in the Q 2 range accessible by this Jefferson Lab experiment. Here, the data are in qualitative agreement with theoretical calculations based on realistic interactions and accurate methods to solve the three-body nuclear problem.« less

  2. Feasibility studies of time-like proton electromagnetic form factors at $$\\overline{\\rm P}$$ANDA at FAIR

    DOE PAGES

    Singh, B.; Erni, W.; Krusche, B.; ...

    2016-10-28

    Simulation results for future measurements of electromagnetic proton form factors atmore » $$\\overline{\\rm P}$$ANDA (FAIR) within the PandaRoot software framework are reported. The statistical precision with which the proton form factors can be determined is estimated. The signal channel p¯p → e +e – is studied on the basis of two different but consistent procedures. The suppression of the main background channel, i.e. p¯p → π +π –, is studied. Furthermore, the background versus signal efficiency, statistical and systematical uncertainties on the extracted proton form factors are evaluated using two different procedures. The results are consistent with those of a previous simulation study using an older, simplified framework. Furthermore, a slightly better precision is achieved in the PandaRoot study in a large range of momentum transfer, assuming the nominal beam conditions and detector performance.« less

  3. Brownian thermal noise in functional optical surfaces

    NASA Astrophysics Data System (ADS)

    Kroker, S.; Dickmann, J.; Rojas Hurtado, C. B.; Heinert, D.; Nawrodt, R.; Levin, Y.; Vyatchanin, S. P.

    2017-07-01

    We present a formalism to compute Brownian thermal noise in functional optical surfaces such as grating reflectors, photonic crystal slabs, or complex metamaterials. Such computations are based on a specific readout variable, typically a surface integral of a dielectric interface displacement weighed by a form factor. This paper shows how to relate this form factor to Maxwell's stress tensor computed on all interfaces of the moving surface. As an example, we examine Brownian thermal noise in monolithic T-shaped grating reflectors. The previous computations by Heinert et al. [Phys. Rev. D 88, 042001 (2013), 10.1103/PhysRevD.88.042001] utilizing a simplified readout form factor produced estimates of thermal noise that are tens of percent higher than those of the exact analysis in the present paper. The relation between the form factor and Maxwell's stress tensor implies a close correlation between the optical properties of functional optical surfaces and thermal noise.

  4. The impact of space travel on dosage form design and use.

    PubMed

    Aronsohn, A; Brazeau, G; Hughes, J

    1999-07-01

    The author speculates on potential factors that may influence the utilization of dosage forms in space. A key assumption is that most of the arguments will be based on current understanding of how dosage forms work on earth. Factors discussed include dosage form stability; and administration of drugs, particularly inhalation and aerosols. A sample experiment used a tissue culture model of drug transfer for passively absorbed drugs to address how alterations in hydrostatic pressure would change paracellular transport.

  5. The south San Fernando Valley fault, Los Angeles California: Myth or reality

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Slosson, J.E.; Phipps, M.B.; Werner, S.L.

    1993-04-01

    Based on related geomorphic and hydrogeologic evidence, the authors have identified the probable existence of a fault system and related Riedel faults along the southerly side of the San Fernando Valley (SFV), Los Angeles, CA. This fault system, which appears to be aligned along a series of pressure ridges, artesian springs and warm water wells, is termed the South SFV Fault for the purpose of this study. The trace of this fault is believed to roughly follow the southern extent of the SFV near the northern base of the east-west trending Santa Monica Mountains. The SFV is a fault-affected synclinalmore » structure bounded on the north, east, and west by well-recognized and documented fault systems. The southern boundary of the SFV is defined by the complexly faulted anticlinal structure of the bordering Santa Monica Mountains. This presentation will suggest that the southern boundary of the SFV (syncline) is controlled by faulting similar to the fault-controlled north, east, and west boundaries. The authors believe that the trace of the fault system in the southeastern portion of the SFV has been somewhat modified and concealed by the erosion and deposition of coarse grained sediments derived from the vast granitic-metamorphic complex of the San Gabriel Mountains to the north, the major watershed, and in part by sediment derived from similar rock type to the east and southeast. The western half of the SFV has been largely filled with fine grained sediments derived from erosion of the surrounding sedimentary uplands. Further modification has occurred due to urbanization of the area. With reference to the fault-affected boundaries on the west, north, and east sides of the SFV, these structures are all considered youthfall and capable of producing earthquakes as the SFF did in 1971. The south-bounding fault may fall within a similar category. Accordingly, the authors believe that the proposed South SFV Fault has been a tectonic feature since the Pliocene epoch.« less

  6. Three-Dimensional Smoothed Particle Hydrodynamics Modeling of Preferential Flow Dynamics at Fracture Intersections on a High-Performance Computing Platform

    NASA Astrophysics Data System (ADS)

    Kordilla, J.; Bresinsky, L. T.

    2017-12-01

    The physical mechanisms that govern preferential flow dynamics in unsaturated fractured rock formations are complex and not well understood. Fracture intersections may act as an integrator of unsaturated flow, leading to temporal delay, intermittent flow and partitioning dynamics. In this work, a three-dimensional Pairwise-Force Smoothed Particle Hydrodynamics (PF-SPH) model is being applied in order to simulate gravity-driven multiphase flow at synthetic fracture intersections. SPH, as a meshless Lagrangian method, is particularly suitable for modeling deformable interfaces, such as three-phase contact dynamics of droplets, rivulets and free-surface films. The static and dynamic contact angle can be recognized as the most important parameter of gravity-driven free-surface flow. In SPH, surface tension and adhesion naturally emerges from the implemented pairwise fluid-fluid (sff) and solid-fluid (ssf) interaction force. The model was calibrated to a contact angle of 65°, which corresponds to the wetting properties of water on Poly(methyl methacrylate). The accuracy of the SPH simulations were validated against an analytical solution of Poiseuille flow between two parallel plates and against laboratory experiments. Using the SPH model, the complex flow mode transitions from droplet to rivulet flow of an experimental study were reproduced. Additionally, laboratory dimensionless scaling experiments of water droplets were successfully replicated in SPH. Finally, SPH simulations were used to investigate the partitioning dynamics of single droplets into synthetic horizontal fractures with various apertures (Δdf = 0, 0.5, 1.0, 1.5, 2.0, 2.5, 3.0, 3.5, 4.0 mm) and offsets (Δdoff = -1.5, -1.0, -0.5, 0, 1.0, 2.0, 3.0 mm). Fluid masses were measured in the domains R1, R2 and R3. The perfect conditions of ideally smooth surfaces and the SPH inherent advantage of particle tracking allow the recognition of small scale partitioning mechanisms and its importance for bulk flow behavior.

  7. Λb→p ℓ-ν¯ ℓ and Λb→Λcℓ-ν¯ ℓ form factors from lattice QCD with relativistic heavy quarks

    NASA Astrophysics Data System (ADS)

    Detmold, William; Lehner, Christoph; Meinel, Stefan

    2015-08-01

    Measurements of the Λb→p ℓ-ν¯ ℓ and Λb→Λcℓ-ν¯ ℓ decay rates can be used to determine the magnitudes of the Cabibbo-Kobayashi-Maskawa matrix elements Vu b and Vc b, provided that the relevant hadronic form factors are known. Here we present a precise calculation of these form factors using lattice QCD with 2 +1 flavors of dynamical domain-wall fermions. The b and c quarks are implemented with relativistic heavy-quark actions, allowing us to work directly at the physical heavy-quark masses. The lattice computation is performed for six different pion masses and two different lattice spacings, using gauge-field configurations generated by the RBC and UKQCD Collaborations. The b →u and b →c currents are renormalized with a mostly nonperturbative method. We extrapolate the form factor results to the physical pion mass and the continuum limit, parametrizing the q2 dependence using z expansions. The form factors are presented in such a way as to enable the correlated propagation of both statistical and systematic uncertainties into derived quantities such as differential decay rates and asymmetries. Using these form factors, we present predictions for the Λb→p ℓ-ν¯ℓ and Λb→Λc ℓ-ν¯ℓ differential and integrated decay rates. Combined with experimental data, our results enable determinations of |Vu b|, |Vc b|, and |Vu b/Vc b| with theory uncertainties of 4.4%, 2.2%, and 4.9%, respectively.

  8. Factor Structure of the Torrance Tests of Creative Thinking Verbal Form B in a Spanish-Speaking Population

    ERIC Educational Resources Information Center

    Krumm, Gabriela; Aranguren, María; Arán Filippetti, Vanessa; Lemos, Viviana

    2016-01-01

    The objective of this study was to compare, through a Confirmatory Factor Analysis, two different theoretical models that explain the operationalized creativity construct with the Verbal Torrance Tests of Creative Thinking (TTCT), Form B. Model 1 is represented by six factors which correspond to each activity and its respective indicators while…

  9. Validation of a brief form of the Perceived Neighborhood Social Cohesion questionnaire.

    PubMed

    Dupuis, Marc; Baggio, Stéphanie; Gmel, Gerhard

    2017-02-01

    The aim of this study was the validation of a brief form of the Perceived Neighborhood Social Cohesion questionnaire using data from 5065 men from the "Cohort Study on Substance-Use Risk Factors." A 9-item scale covering three factors was proposed. Excellent indices of internal consistency were measured (α = .93). The confirmatory factor analyses resulted in acceptable fit indices supporting measurement invariance across French and German forms. Significant correlations were found between the brief form of the Perceived Neighborhood Social Cohesion questionnaire, and satisfaction and self-reported health, providing evidence of the concurrent validity of the scale. Perceived neighborhood social cohesion, and depression and suicide attempts were negatively associated, sustaining the protective effect of perceived social cohesion.

  10. Factor structure of the Minnesota Satisfaction Questionnaire short form for restaurant employees.

    PubMed

    Hancer, Mura; George, R Thomas

    2004-02-01

    The factor structure of the Minnesota Satisfaction Questionnaire short form for nonsupervisory restaurant employees was explored in questions among 2000 employees of three full-service restaurant chains operating in midwestern United States. A total of 2000 surveys were distributed to hourly employees of the three chains. From the mailing, 924 surveys were returned and found useable, a 46.2% response rate. Principal factors analysis identified a four-factor structure for the employees, in contrast to the original two-factor structure, but as in other studies the structure was multifactorial.

  11. Development of short and very short forms of the Children's Behavior Questionnaire.

    PubMed

    Putnam, Samuel P; Rothbart, Mary K

    2006-08-01

    Using data from 468 parents and taking into account internal consistency, breadth of item content, within-scale factor analysis, and patterns of missing data, we developed short (94 items, 15 scales) and very short (36 items, 3 broad scales) forms of the Children's Behavior Questionnaire (CBQ; Rothbart, Ahadi, & Hershey, 1994; Rothbart, Ahadi, Hershey, & Fisher, 2001), a well-established parent-report measure of temperament for children aged 3 to 8 years. We subsequently evaluated the forms with data from 1,189 participants. In mid/high-income and White samples, the CBQ short and very short forms demonstrated both satisfactory internal consistency and criterion validity, and exhibited longitudinal stability and cross-informant agreement comparable to that of the standard CBQ. Internal consistency was somewhat lower among African American and low-income samples for some scales. Very short form scales demonstrated acceptable internal consistency for all samples, and confirmatory factor analyses indicated marginal fit of the very short form items to a three-factor model.

  12. An Investigation of Psychometric Properties of Coping Styles Scale Brief Form: A Study of Validity and Reliability

    ERIC Educational Resources Information Center

    Bacanli, Hasan; Surucu, Mustafa; Ilhan, Tahsin

    2013-01-01

    The aim of the current study was to develop a short form of Coping Styles Scale based on COPE Inventory. A total of 275 undergraduate students (114 female, and 74 male) were administered in the first study. In order to test factors structure of Coping Styles Scale Brief Form, principal components factor analysis and direct oblique rotation was…

  13. Research on design method of the full form ship with minimum thrust deduction factor

    NASA Astrophysics Data System (ADS)

    Zhang, Bao-ji; Miao, Ai-qin; Zhang, Zhu-xin

    2015-04-01

    In the preliminary design stage of the full form ships, in order to obtain a hull form with low resistance and maximum propulsion efficiency, an optimization design program for a full form ship with the minimum thrust deduction factor has been developed, which combined the potential flow theory and boundary layer theory with the optimization technique. In the optimization process, the Sequential Unconstrained Minimization Technique (SUMT) interior point method of Nonlinear Programming (NLP) was proposed with the minimum thrust deduction factor as the objective function. An appropriate displacement is a basic constraint condition, and the boundary layer separation is an additional one. The parameters of the hull form modification function are used as design variables. At last, the numerical optimization example for lines of after-body of 50000 DWT product oil tanker was provided, which indicated that the propulsion efficiency was improved distinctly by this optimal design method.

  14. Lattice QCD and the timelike pion form factor.

    PubMed

    Meyer, Harvey B

    2011-08-12

    We present a formula that allows one to calculate the pion form factor in the timelike region 2m(π) ≤ √(s) ≤ 4m(π) in lattice QCD. The form factor quantifies the contribution of two-pion states to the vacuum polarization. It must be known very accurately in order to reduce the theoretical uncertainty on the anomalous magnetic moment of the muon. At the same time, the formula constitutes a rare example where, in a restricted kinematic regime, the spectral function of a conserved current can be determined from Euclidean observables without an explicit analytic continuation.

  15. Form factors and generalized parton distributions in basis light-front quantization

    NASA Astrophysics Data System (ADS)

    Adhikari, Lekha; Li, Yang; Zhao, Xingbo; Maris, Pieter; Vary, James P.; El-Hady, Alaa Abd

    2016-05-01

    We calculate the elastic form factors and the generalized parton distributions (GPDs) for four low-lying bound states of a demonstration fermion-antifermion system, strong-coupling positronium (e e ¯ ), using basis light-front quantization (BLFQ). By using this approach, we also calculate the impact-parameter-dependent GPDs q (x ,b⃗⊥) to visualize the fermion density in the transverse plane (b⃗⊥). We compare selected results with corresponding quantities in the nonrelativistic limit to reveal relativistic effects. Our results establish the foundation within BLFQ for investigating the form factors and the GPDs for hadronic systems.

  16. Vector and Axial Form Factors Applied to Neutrino Quasielastic Scattering

    NASA Astrophysics Data System (ADS)

    Budd, H.; Bodek, A.; Arrington, J.

    2005-02-01

    We calculate the quasielastic cross sections for neutrino scattering on nucleons using up to date fits to the nucleon elastic electromagnetic form factors GEp, GEn, GMp, GMn, and weak form factors. We show the extraction of F(q). We show the that F(q) has a different contribution to the anti-neutrino cross section, and how the anti-neutrino data can be used to check F(q) extracted from neutrino scattering. (Presented by Howard Budd at NuInt04, Mar. 2004, Laboratori Nazionali del Gran Sasso - INFN - Assergi, Italy [ http://nuint04.lngs.infn.it/])

  17. Electromagnetic form factors of singly heavy baryons in the self-consistent SU(3) chiral quark-soliton model

    NASA Astrophysics Data System (ADS)

    Kim, June-Young; Kim, Hyun-Chul

    2018-06-01

    The self-consistent chiral quark-soliton model is a relativistic pion mean-field approach in the large Nc limit, which describes both light and heavy baryons on an equal footing. In the limit of the infinitely heavy mass of the heavy quark, a heavy baryon can be regarded as Nc-1 valence quarks bound by the pion mean fields, leaving the heavy quark as a color static source. The structure of the heavy baryon in this scheme is mainly governed by the light-quark degrees of freedom. Based on this framework, we evaluate the electromagnetic form factors of the lowest-lying heavy baryons. The rotational 1 /Nc and strange current quark mass corrections in linear order are considered. We discuss the electric charge and magnetic densities of heavy baryons in comparison with those of the nucleons. The results of the electric charge radii of the positive-charged heavy baryons show explicitly that the heavy baryon is a compact object. The electric form factors are presented. The form factor of Σc++ is compared with that from a lattice QCD. We also discuss the results of the magnetic form factors. The magnetic moments of the baryon sextet with spin 1 /2 and the magnetic radii are compared with other works and the lattice data.

  18. Perturbative corrections to B → D form factors in QCD

    NASA Astrophysics Data System (ADS)

    Wang, Yu-Ming; Wei, Yan-Bing; Shen, Yue-Long; Lü, Cai-Dian

    2017-06-01

    We compute perturbative QCD corrections to B → D form factors at leading power in Λ/ m b , at large hadronic recoil, from the light-cone sum rules (LCSR) with B-meson distribution amplitudes in HQET. QCD factorization for the vacuum-to- B-meson correlation function with an interpolating current for the D-meson is demonstrated explicitly at one loop with the power counting scheme {m}_c˜ O(√{Λ {m}_b}) . The jet functions encoding information of the hard-collinear dynamics in the above-mentioned correlation function are complicated by the appearance of an additional hard-collinear scale m c , compared to the counterparts entering the factorization formula of the vacuum-to- B-meson correction function for the construction of B → π from factors. Inspecting the next-to-leading-logarithmic sum rules for the form factors of B → Dℓν indicates that perturbative corrections to the hard-collinear functions are more profound than that for the hard functions, with the default theory inputs, in the physical kinematic region. We further compute the subleading power correction induced by the three-particle quark-gluon distribution amplitudes of the B-meson at tree level employing the background gluon field approach. The LCSR predictions for the semileptonic B → Dℓν form factors are then extrapolated to the entire kinematic region with the z-series parametrization. Phenomenological implications of our determinations for the form factors f BD +,0 ( q 2) are explored by investigating the (differential) branching fractions and the R( D) ratio of B → Dℓν and by determining the CKM matrix element |V cb | from the total decay rate of B → Dμν μ .

  19. Children's Computation of Complex Linguistic Forms: A Study of Frequency and Imageability Effects

    PubMed Central

    Dye, Cristina D.; Walenski, Matthew; Prado, Elizabeth L.; Mostofsky, Stewart; Ullman, Michael T.

    2013-01-01

    This study investigates the storage vs. composition of inflected forms in typically-developing children. Children aged 8–12 were tested on the production of regular and irregular past-tense forms. Storage (vs. composition) was examined by probing for past-tense frequency effects and imageability effects – both of which are diagnostic tests for storage – while controlling for a number of confounding factors. We also examined sex as a factor. Irregular inflected forms, which must depend on stored representations, always showed evidence of storage (frequency and/or imageability effects), not only across all children, but also separately in both sexes. In contrast, for regular forms, which could be either stored or composed, only girls showed evidence of storage. This pattern is similar to that found in previously-acquired adult data from the same task, with the notable exception that development affects which factors influence the storage of regulars in females: imageability plays a larger role in girls, and frequency in women. Overall, the results suggest that irregular inflected forms are always stored (in children and adults, and in both sexes), whereas regulars can be either composed or stored, with their storage a function of various item- and subject-level factors. PMID:24040318

  20. [Enviromental factors in the pathogenesis of thyroid cancer].

    PubMed

    Gubetta, L; Costa, A

    1978-07-14

    Local factors with a possible influence on the frequency and histological type of thyroid cancer are examined in the light of cases observed at the Mauriziano Hospital in the last 10 years. The overall number of cases has been increasing and papilliferous forms have been more common than follicular forms. Iodine deficiency and thyrotropin hyper-stimulation encourage onset and account for the higher frequency of thyroid cancer in endemic areas, where, however, follicular forms are more common. Ironising radiation is a direct cause, particularly of papilliferous forms arising after exposure during youth.

  1. Axial-vector form factors of the nucleon from lattice QCD

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gupta, Rajan; Jang, Yong-Chull; Lin, Huey-Wen

    In this paper, we present results for the form factors of the isovector axial vector current in the nucleon state using large scale simulations of lattice QCD. The calculations were done using eight ensembles of gauge configurations generated by the MILC collaboration using the HISQ action with 2 + 1 + 1 dynamical flavors. These ensembles span three lattice spacings a ≈ 0.06 , 0.09, and 0.12 fm and light-quark masses corresponding to the pion masses M π ≈ 135, 225, and 310 MeV. High-statistics estimates allow us to quantify systematic uncertainties in the extraction of G A (Q 2)more » and the induced pseudoscalar form factor G P(Q 2) . We perform a simultaneous extrapolation in the lattice spacing, lattice volume and light-quark masses of the axial charge radius r A data to obtain physical estimates. Using the dipole ansatz to fit the Q 2 behavior we obtain r A | dipole = 0.49(3) fm , which corresponds to M A = 1.39(9) GeV , and is consistent with M A = 1.35(17) GeV obtained by the miniBooNE collaboration. The estimate obtained using the z -expansion is r A | z - expansion = 0.46(6) fm, and the combined result is r A | combined = 0.48(4) fm. Analysis of the induced pseudoscalar form factor G P (Q 2) yields low estimates for g* P and g πNN compared to their phenomenological values. To understand these, we analyze the partially conserved axial current (PCAC) relation by also calculating the pseudoscalar form factor. Lastly, we find that these low values are due to large deviations in the PCAC relation between the three form factors, and in the pion-pole dominance hypothesis.« less

  2. The pion: an enigma within the Standard Model

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Horn, Tanja; Roberts, Craig D.

    2016-05-27

    Almost 50 years after the discovery of gluons & quarks, we are only just beginning to understand how QCD builds the basic bricks for nuclei: neutrons, protons, and the pions that bind them. QCD is characterised by two emergent phenomena: confinement & dynamical chiral symmetry breaking (DCSB). They are expressed with great force in the character of the pion. In turn, pion properties suggest that confinement & DCSB are closely connected. As both a Nambu-Goldstone boson and a quark-antiquark bound-state, the pion is unique in Nature. Developing an understanding of its properties is thus critical to revealing basic features ofmore » the Standard Model. We describe experimental progress in this direction, made using electromagnetic probes, highlighting both improvements in the precision of charged-pion form factor data, achieved in the past decade, and new results on the neutral-pion transition form factor. Both challenge existing notions of pion structure. We also provide a theoretical context for these empirical advances, first explaining how DCSB works to guarantee that the pion is unnaturally light; but also, nevertheless, ensures the pion is key to revealing the mechanisms that generate nearly all the mass of hadrons. Our discussion unifies the charged-pion elastic and neutral-pion transition form factors, and the pion's twist-2 parton distribution amplitude. It also indicates how studies of the charged-kaon form factor can provide significant contributions. Importantly, recent predictions for the large-$Q^2$ behaviour of the pion form factor can be tested by experiments planned at JLab 12. Those experiments will extend precise charged-pion form factor data to momenta that can potentially serve in validating factorisation theorems in QCD, exposing the transition between the nonperturbative and perturbative domains, and thereby reaching a goal that has long driven hadro-particle physics.« less

  3. Λ b → pℓ¯ν¯ ℓ and Λ b → Λ cℓ¯ν¯ ℓ form factors from lattice QCD with relativistic heavy quarks

    DOE PAGES

    Detmold, William; Lehner, Christoph; Meinel, Stefan

    2015-08-04

    Measurements of the Λ b → pℓ¯ν¯ ℓ and Λ b → Λ cℓ¯ν¯ ℓ decay rates can be used to determine the magnitudes of the Cabibbo-Kobayashi-Maskawa matrix elements V ub and V cb, provided that the relevant hadronic form factors are known. Here we present a precise calculation of these form factors using lattice QCD with 2+1 flavors of dynamical domain-wall fermions. The b and c quarks are implemented with relativistic heavy-quark actions, allowing us to work directly at the physical heavy-quark masses. The lattice computation is performed for six different pion masses and two different lattice spacings, usingmore » gauge-field configurations generated by the RBC and UKQCD Collaborations. The b → u and b → c currents are renormalized with a mostly nonperturbative method. We extrapolate the form factor results to the physical pion mass and the continuum limit, parametrizing the q² dependence using z expansions. The form factors are presented in such a way as to enable the correlated propagation of both statistical and systematic uncertainties into derived quantities such as differential decay rates and asymmetries. Using these form factors, we present predictions for the Λ b → pℓ¯ν¯ ℓ and Λ b → Λ cℓ¯ν¯ ℓdifferential and integrated decay rates. Combined with experimental data, our results enable determinations of |V ub|, |V cb|, and |V ub/V cb| with theory uncertainties of 4.4%, 2.2%, and 4.9%, respectively.« less

  4. Axial-vector form factors of the nucleon from lattice QCD

    DOE PAGES

    Gupta, Rajan; Jang, Yong-Chull; Lin, Huey-Wen; ...

    2017-12-04

    In this paper, we present results for the form factors of the isovector axial vector current in the nucleon state using large scale simulations of lattice QCD. The calculations were done using eight ensembles of gauge configurations generated by the MILC collaboration using the HISQ action with 2 + 1 + 1 dynamical flavors. These ensembles span three lattice spacings a ≈ 0.06 , 0.09, and 0.12 fm and light-quark masses corresponding to the pion masses M π ≈ 135, 225, and 310 MeV. High-statistics estimates allow us to quantify systematic uncertainties in the extraction of G A (Q 2)more » and the induced pseudoscalar form factor G P(Q 2) . We perform a simultaneous extrapolation in the lattice spacing, lattice volume and light-quark masses of the axial charge radius r A data to obtain physical estimates. Using the dipole ansatz to fit the Q 2 behavior we obtain r A | dipole = 0.49(3) fm , which corresponds to M A = 1.39(9) GeV , and is consistent with M A = 1.35(17) GeV obtained by the miniBooNE collaboration. The estimate obtained using the z -expansion is r A | z - expansion = 0.46(6) fm, and the combined result is r A | combined = 0.48(4) fm. Analysis of the induced pseudoscalar form factor G P (Q 2) yields low estimates for g* P and g πNN compared to their phenomenological values. To understand these, we analyze the partially conserved axial current (PCAC) relation by also calculating the pseudoscalar form factor. Lastly, we find that these low values are due to large deviations in the PCAC relation between the three form factors, and in the pion-pole dominance hypothesis.« less

  5. The Nucleon Axial Form Factor and Staggered Lattice QCD

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Meyer, Aaron Scott

    The study of neutrino oscillation physics is a major research goal of the worldwide particle physics program over the upcoming decade. Many new experiments are being built to study the properties of neutrinos and to answer questions about the phenomenon of neutrino oscillation. These experiments need precise theoretical cross sections in order to access fundamental neutrino properties. Neutrino oscillation experiments often use large atomic nuclei as scattering targets, which are challenging for theorists to model. Nuclear models rely on free-nucleon amplitudes as inputs. These amplitudes are constrained by scattering experiments with large nuclear targets that rely on the very samemore » nuclear models. The work in this dissertation is the rst step of a new initiative to isolate and compute elementary amplitudes with theoretical calculations to support the neutrino oscillation experimental program. Here, the eort focuses on computing the axial form factor, which is the largest contributor of systematic error in the primary signal measurement process for neutrino oscillation studies, quasielastic scattering. Two approaches are taken. First, neutrino scattering data on a deuterium target are reanalyzed with a model-independent parametrization of the axial form factor to quantify the present uncertainty in the free-nucleon amplitudes. The uncertainties on the free-nucleon cross section are found to be underestimated by about an order of magnitude compared to the ubiquitous dipole model parametrization. The second approach uses lattice QCD to perform a rst-principles computation of the nucleon axial form factor. The Highly Improved Staggered Quark (HISQ) action is employed for both valence and sea quarks. The results presented in this dissertation are computed at physical pion mass for one lattice spacing. This work presents a computation of the axial form factor at zero momentum transfer, and forms the basis for a computation of the axial form factor momentum dependence with an extrapolation to the continuum limit and a full systematic error budget.« less

  6. What Is Deep Vein Thrombosis?

    MedlinePlus

    ... the blood to trigger the activity of the enzyme thrombin. Active thrombin then forms long protein strands that clump together with platelets and red blood cells to form clots. Read less Risk Factors Risk factors for VTE include a history of a previous VTE event; surgery; medical conditions ...

  7. Lattice calculation of electric dipole moments and form factors of the nucleon

    NASA Astrophysics Data System (ADS)

    Abramczyk, M.; Aoki, S.; Blum, T.; Izubuchi, T.; Ohki, H.; Syritsyn, S.

    2017-07-01

    We analyze commonly used expressions for computing the nucleon electric dipole form factors (EDFF) F3 and moments (EDM) on a lattice and find that they lead to spurious contributions from the Pauli form factor F2 due to inadequate definition of these form factors when parity mixing of lattice nucleon fields is involved. Using chirally symmetric domain wall fermions, we calculate the proton and the neutron EDFF induced by the C P -violating quark chromo-EDM interaction using the corrected expression. In addition, we calculate the electric dipole moment of the neutron using a background electric field that respects time translation invariance and boundary conditions, and we find that it decidedly agrees with the new formula but not the old formula for F3. Finally, we analyze some selected lattice results for the nucleon EDM and observe that after the correction is applied, they either agree with zero or are substantially reduced in magnitude, thus reconciling their difference from phenomenological estimates of the nucleon EDM.

  8. Parity-violating electroweak asymmetry in e→ p scattering

    NASA Astrophysics Data System (ADS)

    Aniol, K. A.; Armstrong, D. S.; Averett, T.; Baylac, M.; Burtin, E.; Calarco, J.; Cates, G. D.; Cavata, C.; Chai, Z.; Chang, C. C.; Chen, J.-P.; Chudakov, E.; Cisbani, E.; Coman, M.; Dale, D.; Deur, A.; Djawotho, P.; Epstein, M. B.; Escoffier, S.; Ewell, L.; Falletto, N.; Finn, J. M.; Fissum, K.; Fleck, A.; Frois, B.; Frullani, S.; Gao, J.; Garibaldi, F.; Gasparian, A.; Gerstner, G. M.; Gilman, R.; Glamazdin, A.; Gomez, J.; Gorbenko, V.; Hansen, O.; Hersman, F.; Higinbotham, D. W.; Holmes, R.; Holtrop, M.; Humensky, T. B.; Incerti, S.; Iodice, M.; de Jager, C. W.; Jardillier, J.; Jiang, X.; Jones, M. K.; Jorda, J.; Jutier, C.; Kahl, W.; Kelly, J. J.; Kim, D. H.; Kim, M.-J.; Kim, M. S.; Kominis, I.; Kooijman, E.; Kramer, K.; Kumar, K. S.; Kuss, M.; Lerose, J.; de Leo, R.; Leuschner, M.; Lhuillier, D.; Liang, M.; Liyanage, N.; Lourie, R.; Madey, R.; Malov, S.; Margaziotis, D. J.; Marie, F.; Markowitz, P.; Martino, J.; Mastromarino, P.; McCormick, K.; McIntyre, J.; Meziani, Z.-E.; Michaels, R.; Milbrath, B.; Miller, G. W.; Mitchell, J.; Morand, L.; Neyret, D.; Pedrisat, C.; Petratos, G. G.; Pomatsalyuk, R.; Price, J. S.; Prout, D.; Punjabi, V.; Pussieux, T.; Quéméner, G.; Ransome, R. D.; Relyea, D.; Roblin, Y.; Roche, J.; Rutledge, G. A.; Rutt, P. M.; Rvachev, M.; Sabatie, F.; Saha, A.; Souder, P. A.; Spradlin, M.; Strauch, S.; Suleiman, R.; Templon, J.; Teresawa, T.; Thompson, J.; Tieulent, R.; Todor, L.; Tonguc, B. T.; Ulmer, P. E.; Urciuoli, G. M.; Vlahovic, B.; Wijesooriya, K.; Wilson, R.; Wojtsekhowski, B.; Woo, R.; Xu, W.; Younus, I.; Zhang, C.

    2004-06-01

    We have measured the parity-violating electroweak asymmetry in the elastic scattering of polarized electrons from protons. Significant contributions to this asymmetry could arise from the contributions of strange form factors in the nucleon. The measured asymmetry is A= -15.05±0.98 (stat) ±0.56 (syst) ppm at the kinematic point < θlab > =12.3° and < Q2 > =0.477 (GeV/c)2 . Based on these data as well as data on electromagnetic form factors, we extract the linear combination of strange form factors GsE +0.392 GsM = 0.014±0.020±0.010 , where the first error arises from this experiment and the second arises from the electromagnetic form factor data. This paper provides a full description of the special experimental techniques employed for precisely measuring the small asymmetry, including the first use of a strained GaAs crystal and a laser-Compton polarimeter in a fixed target parity-violation experiment.

  9. Partonic structure of neutral pseudoscalars via two photon transition form factors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Raya, Khepani; Ding, Minghui; Bashir, Adnan

    Here, the γγ* → η c,b transition form factors are computed using a continuum approach to the two valence-body bound-state problem in relativistic quantum field theory, and thereby unified with equivalent calculations of electromagnetic pion elastic and transition form factors. The resulting γγ* → η c form factor, G ηc(Q 2), is consistent with available data; significantly, at accessible momentum transfers, Q 2G ηc(Q 2) lies well below its conformal limit. These observations confirm that the leading-twist parton distribution amplitudes of heavy-heavy bound states are compressed relative to the conformal limit. A clear understanding of the distribution of valence quarksmore » within mesons thus emerges, a picture which connects Goldstone modes, built from the lightest quarks in nature, with systems containing the heaviest valence quarks that can now be studied experimentally, and highlights basic facts about manifestations of mass within the Standard Model.« less

  10. Partonic structure of neutral pseudoscalars via two photon transition form factors

    DOE PAGES

    Raya, Khepani; Ding, Minghui; Bashir, Adnan; ...

    2017-04-10

    Here, the γγ* → η c,b transition form factors are computed using a continuum approach to the two valence-body bound-state problem in relativistic quantum field theory, and thereby unified with equivalent calculations of electromagnetic pion elastic and transition form factors. The resulting γγ* → η c form factor, G ηc(Q 2), is consistent with available data; significantly, at accessible momentum transfers, Q 2G ηc(Q 2) lies well below its conformal limit. These observations confirm that the leading-twist parton distribution amplitudes of heavy-heavy bound states are compressed relative to the conformal limit. A clear understanding of the distribution of valence quarksmore » within mesons thus emerges, a picture which connects Goldstone modes, built from the lightest quarks in nature, with systems containing the heaviest valence quarks that can now be studied experimentally, and highlights basic facts about manifestations of mass within the Standard Model.« less

  11. The Kroll-Lee-Zumino Model and Pion Form Factors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dominguez, C. A.; Loewe, M.

    2010-08-04

    At the one loop level, we make use of the renormalizable Abelian quantum field theory model of Kroll, Lee, and Zumino (KLZ) in order to compute the vertex corrections to the tree-level, Vector Meson Dominance (VMD) electromagnetic pion form factor. This result, together with the one-loop vacuum polarization contribution, implies an electromagnetic pion form factor which is in outstanding agreement with data in the whole range of accessible momentum transfers in the space-like region. The time-like form factor, which reproduces the Gounaris-Sakurai formula at and near the rho-meson peak, remains unaffected by the vertex correction at order O(g{sup 2}). Wemore » also use the KLZ model to compute the pion scalar radius at the one loop level, finding S = 0.40 fm{sup 2}. From this value we find for the low energy constant of chiral perturbation theory l{sub 4} = 3.4.« less

  12. Thermal form factor approach to the ground-state correlation functions of the XXZ chain in the antiferromagnetic massive regime

    NASA Astrophysics Data System (ADS)

    Dugave, Maxime; Göhmann, Frank; Kozlowski, Karol K.; Suzuki, Junji

    2016-09-01

    We use the form factors of the quantum transfer matrix in the zero-temperature limit in order to study the two-point ground-state correlation functions of the XXZ chain in the antiferromagnetic massive regime. We obtain novel form factor series representations of the correlation functions which differ from those derived either from the q-vertex-operator approach or from the algebraic Bethe Ansatz approach to the usual transfer matrix. We advocate that our novel representations are numerically more efficient and allow for a straightforward calculation of the large-distance asymptotic behaviour of the two-point functions. Keeping control over the temperature corrections to the two-point functions we see that these are of order {T}∞ in the whole antiferromagnetic massive regime. The isotropic limit of our result yields a novel form factor series representation for the two-point correlation functions of the XXX chain at zero magnetic field. Dedicated to the memory of Petr Petrovich Kulish.

  13. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Asahina, Yuta; Kawashima, Tomohisa; Furukawa, Naoko

    The formation mechanism of CO clouds observed with the NANTEN2 and Mopra telescopes toward the stellar cluster Westerlund 2 is studied by 3D magnetohydrodynamic simulations, taking into account the interstellar cooling. These molecular clouds show a peculiar shape composed of an arc-shaped cloud on one side of the TeV γ -ray source HESS J1023-575 and a linear distribution of clouds (jet clouds) on the other side. We propose that these clouds are formed by the interaction of a jet with clumps of interstellar neutral hydrogen (H i). By studying the dependence of the shape of dense cold clouds formed bymore » shock compression and cooling on the filling factor of H i clumps, we found that the density distribution of H i clumps determines the shape of molecular clouds formed by the jet–cloud interaction: arc clouds are formed when the filling factor is large. On the other hand, when the filling factor is small, molecular clouds align with the jet. The jet propagates faster in models with small filling factors.« less

  14. Accessing the Elastic Form-Factors of the $Delta(1232)$ Using the Beam-Normal Asymmetry

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dalton, Mark M.

    2016-08-01

    The beam-normal single-spin asymmetry,more » $$B_n$$, exists in the scattering of high energy electrons, polarized transverse to their direction of motion, from nuclear targets. To first order, this asymmetry is caused by the interference of the one-photon exchange amplitude with the imaginary part of the two-photon exchange amplitude. Measurements of $$B_n$$, for the production of a $$\\Delta(1232)$$ resonance from a proton target, will soon become available from the Qweak experiment at Jefferson Lab and the A4 experiment at Mainz. The imaginary part of two-photon exchange allows only intermediate states that are on-shell, including the $$\\Delta$$ itself. Therefore such data is sensitive to $$\\gamma\\Delta\\Delta$$, the elastic form-factors of the $$\\Delta$$. This article will introduce the form-factors of the $$\\Delta$$, discuss what might be learned about the elastic form-factors from these new data, describe ongoing efforts in calculation and measurement, and outline the possibility of future measurements.« less

  15. Heavy-to-light scalar form factors from Muskhelishvili-Omnès dispersion relations

    NASA Astrophysics Data System (ADS)

    Yao, D.-L.; Fernandez-Soler, P.; Albaladejo, M.; Guo, F.-K.; Nieves, J.

    2018-04-01

    By solving the Muskhelishvili-Omnès integral equations, the scalar form factors of the semileptonic heavy meson decays D→ π \\bar{ℓ }ν _ℓ , D→ {\\bar{K}} \\bar{ℓ }ν _ℓ , {\\bar{B}}→ π ℓ \\bar{ν }_ℓ and {\\bar{B}}_s→ K ℓ \\bar{ν }_ℓ are simultaneously studied. As input, we employ unitarized heavy meson-Goldstone boson chiral coupled-channel amplitudes for the energy regions not far from thresholds, while, at high energies, adequate asymptotic conditions are imposed. The scalar form factors are expressed in terms of Omnès matrices multiplied by vector polynomials, which contain some undetermined dispersive subtraction constants. We make use of heavy quark and chiral symmetries to constrain these constants, which are fitted to lattice QCD results both in the charm and the bottom sectors, and in this latter sector to the light-cone sum rule predictions close to q^2=0 as well. We find a good simultaneous description of the scalar form factors for the four semileptonic decay reactions. From this combined fit, and taking advantage that scalar and vector form factors are equal at q^2=0, we obtain |V_{cd}|=0.244± 0.022, |V_{cs}|=0.945± 0.041 and |V_{ub}|=(4.3± 0.7)× 10^{-3} for the involved Cabibbo-Kobayashi-Maskawa (CKM) matrix elements. In addition, we predict the following vector form factors at q^2=0: |f_+^{D→ η }(0)|=0.01± 0.05, |f_+^{D_s→ K}(0)|=0.50 ± 0.08, |f_+^{D_s→ η }(0)|=0.73± 0.03 and |f_+^{{\\bar{B}}→ η }(0)|=0.82 ± 0.08, which might serve as alternatives to determine the CKM elements when experimental measurements of the corresponding differential decay rates become available. Finally, we predict the different form factors above the q^2-regions accessible in the semileptonic decays, up to moderate energies amenable to be described using the unitarized coupled-channel chiral approach.

  16. Using the ALPHA form in practice to assess antenatal psychosocial health

    PubMed Central

    Reid, A J; Biringer, A; Carroll, J D; Midmer, D; Wilson, L M; Chalmers, B; Stewart, D E

    1998-01-01

    BACKGROUND: The assessment of the psychosocial health of pregnant women and their families, although recommended, is not carried out by most practitioners. One reason is the lack of a practical and evidence-based tool. In response, a multidisciplinary group created the Antenatal Psychosocial Health Assessment (ALPHA) form. This article describes the development of this tool and experience with it in an initial field trial. METHODS: A systematic literature review revealed 15 antenatal psychosocial risk factors associated with poor postpartum family outcomes of woman abuse, child abuse, postpartum depression, marital/couple dysfunction and increased physical illness. The ALPHA form, incorporating these risk factors, was developed and refined through several focus groups. It was then used by 5 obstetricians, 10 family physicians, 7 midwives and 4 antenatal clinic nurses in various urban, rural and culturally diverse locations across Ontario. After 3 months, these health care providers met in focus groups to discuss their experiences. A sample of pregnant women assessed using the ALPHA form were interviewed about their experience as well. Results were analysed according to qualitative methods. RESULTS: The final version of the ALPHA form grouped the 15 risk factors into 4 categories--family factors, maternal factors, substance abuse and family violence--with suggested questions for each area of enquiry. The health care providers uniformly reported that the form helped them to uncover new and often surprising information, even when the women were well known to them. Incorporating the form into practice was usually accomplished after a period of familiarization. Most of the providers said the form was useful and would continue to use it if it became part of standard care. The pregnant women in the sample said they valued the enquiry and felt comfortable with the process, unless there were large cultural barriers. INTERPRETATION: The ALPHA form appears to be an important tool in assessing psychosocial health in pregnancy and to be readily integrated into practice. More study is required to quantify the number of risks identified and resources used, to determine the form's reliability and validity and, ultimately, to assess the effect of its use on postpartum outcomes. PMID:9780969

  17. The factor structure and construct validity of the inventory of callous-unemotional traits in Chinese undergraduate students.

    PubMed

    Wang, Meng-Cheng; Gao, Yu; Deng, Jiaxin; Lai, Hongyu; Deng, Qiaowen; Armour, Cherie

    2017-01-01

    The current study assesses the factor structure and construct validity of the self-reported Inventory of Callous-Unemotional Traits (ICU) in 637 Chinese community adults (mean age = 25.98, SD = 5.79). A series of theoretical models proposed in previous studies were tested through confirmatory factor analyses. Results indicated that a shortened form that consists of 11 items (ICU-11) to assess callousness and uncaring factors has excellent overall fit. Additionally, correlations with a wide range of external variables demonstrated that this shortened form has similar construct validity compared to the original ICU. In conclusion, our findings suggest that the ICU-11 may be a promising self-report tool that could be a good substitute for the original form to assess callous-uncaring traits in adults.

  18. Radiative corrections to the η(') Dalitz decays

    NASA Astrophysics Data System (ADS)

    Husek, Tomáš; Kampf, Karol; Novotný, Jiří; Leupold, Stefan

    2018-05-01

    We provide the complete set of radiative corrections to the Dalitz decays η(')→ℓ+ℓ-γ beyond the soft-photon approximation, i.e., over the whole range of the Dalitz plot and with no restrictions on the energy of a radiative photon. The corrections inevitably depend on the η(')→ γ*γ(*) transition form factors. For the singly virtual transition form factor appearing, e.g., in the bremsstrahlung correction, recent dispersive calculations are used. For the one-photon-irreducible contribution at the one-loop level (for the doubly virtual form factor), we use a vector-meson-dominance-inspired model while taking into account the η -η' mixing.

  19. Nucleon form factors in generalized parton distributions at high momentum transfers

    NASA Astrophysics Data System (ADS)

    Sattary Nikkhoo, Negin; Shojaei, Mohammad Reza

    2018-05-01

    This paper aims at calculating the elastic form factors for a nucleon by considering the extended Regge and modified Gaussian ansatzes based on the generalized parton distributions. To reach this goal, we have considered three different parton distribution functions (PDFs) and have compared the obtained results among them for high momentum transfer ranges. Minimum free parameters have been applied in our parametrization. After achieving the form factors, we calculate the electric radius and the transversely unpolarized and polarized densities for the nucleon. Furthermore, we obtain the impact-parameter-dependent PDFs. Finally, we compare our obtained data with the results of previous studies.

  20. HQET form factors for Bs → Klv decays beyond leading order

    NASA Astrophysics Data System (ADS)

    Banerjee, Debasish; Koren, Mateusz; Simma, Hubert; Sommer, Rainer

    2018-03-01

    We compute semi-leptonic Bs decay form factors using Heavy Quark Effective Theory on the lattice. To obtain good control of the 1 /mb expansion, one has to take into account not only the leading static order but also the terms arising at O (1/mb): kinetic, spin and current insertions. We show results for these terms calculated through the ratio method, using our prior results for the static order. After combining them with non-perturbative HQET parameters they can be continuum-extrapolated to give the QCD form factor correct up to O (1/mb2) corrections and without O (αs(mb)n) corrections.

  1. Charge form factor of the neutron at low momentum transfer from the 2H-->(e-->,e'n)1H reaction.

    PubMed

    Geis, E; Kohl, M; Ziskin, V; Akdogan, T; Arenhövel, H; Alarcon, R; Bertozzi, W; Booth, E; Botto, T; Calarco, J; Clasie, B; Crawford, C B; DeGrush, A; Donnelly, T W; Dow, K; Farkhondeh, M; Fatemi, R; Filoti, O; Franklin, W; Gao, H; Gilad, S; Hasell, D; Karpius, P; Kolster, H; Lee, T; Maschinot, A; Matthews, J; McIlhany, K; Meitanis, N; Milner, R G; Rapaport, J; Redwine, R P; Seely, J; Shinozaki, A; Sirca, S; Sindile, A; Six, E; Smith, T; Steadman, M; Tonguc, B; Tschalaer, C; Tsentalovich, E; Turchinetz, W; Xiao, Y; Xu, W; Zhang, C; Zhou, Z; Zwart, T

    2008-07-25

    We report new measurements of the neutron charge form factor at low momentum transfer using quasielastic electrodisintegration of the deuteron. Longitudinally polarized electrons at an energy of 850 MeV were scattered from an isotopically pure, highly polarized deuterium gas target. The scattered electrons and coincident neutrons were measured by the Bates Large Acceptance Spectrometer Toroid (BLAST) detector. The neutron form factor ratio GEn/GMn was extracted from the beam-target vector asymmetry AedV at four-momentum transfers Q2=0.14, 0.20, 0.29, and 0.42 (GeV/c)2.

  2. Effect of Educational Agent and Its Form Characteristics on Problem Solving Ability Perception of Students in Online Task Based Learning Media

    ERIC Educational Resources Information Center

    Akyuz, Halil Ibrahim; Keser, Hafize

    2015-01-01

    The aim of this study is to investigate the effect of an educational agent, used in online task based learning media, and its form characteristics on problem solving ability perceptions of students. 2x2 factorial design is used in this study. The first study factor is the role of the educational agent and the second factor is form characteristics…

  3. Up, down, and strange nucleon axial form factors from lattice QCD

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Green, Jeremy; Hasan, Nesreen; Meinel, Stefan

    Here, we report a calculation of the nucleon axial form factorsmore » $$G_A^q(Q^2)$$ and $$G_P^q(Q^2)$$ for all three light quark flavors $$q\\in\\{u,d,s\\}$$ in the range $$0\\leq Q^2\\lesssim 1.2\\text{ GeV}^2$$ using lattice QCD. Our work was done using a single ensemble with pion mass 317 MeV and made use of the hierarchical probing technique to efficiently evaluate the required disconnected loops. We perform nonperturbative renormalization of the axial current, including a nonperturbative treatment of the mixing between light and strange currents due to the singlet-nonsinglet difference caused by the axial anomaly. The form factor shapes are fit using the model-independent $z$ expansion. From $$G_A^q(Q^2)$$, we determine the quark contributions to the nucleon spin and axial radii. By extrapolating the isovector $$G_P^{u-d}(Q^2)$$, we obtain the induced pseudoscalar coupling relevant for ordinary muon capture and the pion-nucleon coupling constant. We also found that the disconnected contributions to $$G_P$$ form factors are large, and give an interpretation based on the dominant influence of the pseudoscalar poles in these form factors.« less

  4. Up, down, and strange nucleon axial form factors from lattice QCD

    DOE PAGES

    Green, Jeremy; Hasan, Nesreen; Meinel, Stefan; ...

    2017-06-14

    Here, we report a calculation of the nucleon axial form factorsmore » $$G_A^q(Q^2)$$ and $$G_P^q(Q^2)$$ for all three light quark flavors $$q\\in\\{u,d,s\\}$$ in the range $$0\\leq Q^2\\lesssim 1.2\\text{ GeV}^2$$ using lattice QCD. Our work was done using a single ensemble with pion mass 317 MeV and made use of the hierarchical probing technique to efficiently evaluate the required disconnected loops. We perform nonperturbative renormalization of the axial current, including a nonperturbative treatment of the mixing between light and strange currents due to the singlet-nonsinglet difference caused by the axial anomaly. The form factor shapes are fit using the model-independent $z$ expansion. From $$G_A^q(Q^2)$$, we determine the quark contributions to the nucleon spin and axial radii. By extrapolating the isovector $$G_P^{u-d}(Q^2)$$, we obtain the induced pseudoscalar coupling relevant for ordinary muon capture and the pion-nucleon coupling constant. We also found that the disconnected contributions to $$G_P$$ form factors are large, and give an interpretation based on the dominant influence of the pseudoscalar poles in these form factors.« less

  5. Transformations of Mathematical and Stimulus Functions

    PubMed Central

    Ninness, Chris; Barnes-Holmes, Dermot; Rumph, Robin; McCuller, Glen; Ford, Angela M; Payne, Robert; Ninness, Sharon K; Smith, Ronald J; Ward, Todd A; Elliott, Marc P

    2006-01-01

    Following a pretest, 8 participants who were unfamiliar with algebraic and trigonometric functions received a brief presentation on the rectangular coordinate system. Next, they participated in a computer-interactive matching-to-sample procedure that trained formula-to-formula and formula-to-graph relations. Then, they were exposed to 40 novel formula-to-graph tests and 10 novel graph-to-formula tests. Seven of the 8 participants showed substantial improvement in identifying formula-to-graph relations; however, in the test of novel graph-to-formula relations, participants tended to select equations in their factored form. Next, we manipulated contextual cues in the form of rules regarding mathematical preferences. First, we informed participants that standard forms of equations were preferred over factored forms. In a subsequent test of 10 additional novel graph-to-formula relations, participants shifted their selections to favor equations in their standard form. This preference reversed during 10 more tests when financial reward was made contingent on correct identification of formulas in factored form. Formula preferences and transformation of novel mathematical and stimulus functions are discussed. PMID:17020211

  6. Molecular cloning and biochemical characterization of rabbit factor XI.

    PubMed Central

    Sinha, Dipali; Marcinkiewicz, Mariola; Gailani, David; Walsh, Peter N

    2002-01-01

    Human factor XI, a plasma glycoprotein required for normal haemostasis, is a homodimer (160 kDa) formed by a single interchain disulphide bond linking the Cys-321 of each Apple 4 domain. Bovine, porcine and murine factor XI are also disulphide-linked homodimers. Rabbit factor XI, however, is an 80 kDa polypeptide on non-reducing SDS/PAGE, suggesting that rabbit factor XI exists and functions physiologically either as a monomer, as does prekallikrein, a structural homologue to factor XI, or as a non-covalent homodimer. We have investigated the structure and function of rabbit factor XI to gain insight into the relation between homodimeric structure and factor XI function. Characterization of the cDNA sequence of rabbit factor XI and its amino acid translation revealed that in the rabbit protein a His residue replaces the Cys-321 that forms the interchain disulphide linkage in human factor XI, explaining why rabbit factor XI is a monomer in non-reducing SDS/PAGE. On size-exclusion chromatography, however, purified plasma rabbit factor XI, like the human protein and unlike prekallikrein, eluted as a dimer, demonstrating that rabbit factor XI circulates as a non-covalent dimer. In functional assays rabbit factor XI and human factor XI behaved similarly. Both monomeric and dimeric factor XI were detected in extracts of cells expressing rabbit factor XI. We conclude that the failure of rabbit factor XI to form a covalent homodimer due to the replacement of Cys-321 with His does not impair its functional activity because it exists in plasma as a non-covalent homodimer and homodimerization is an intracellular process. PMID:12084014

  7. Universal analytical scattering form factor for shell-, core-shell, or homogeneous particles with continuously variable density profile shape.

    PubMed

    Foster, Tobias

    2011-09-01

    A novel analytical and continuous density distribution function with a widely variable shape is reported and used to derive an analytical scattering form factor that allows us to universally describe the scattering from particles with the radial density profile of homogeneous spheres, shells, or core-shell particles. Composed by the sum of two Fermi-Dirac distribution functions, the shape of the density profile can be altered continuously from step-like via Gaussian-like or parabolic to asymptotically hyperbolic by varying a single "shape parameter", d. Using this density profile, the scattering form factor can be calculated numerically. An analytical form factor can be derived using an approximate expression for the original Fermi-Dirac distribution function. This approximation is accurate for sufficiently small rescaled shape parameters, d/R (R being the particle radius), up to values of d/R ≈ 0.1, and thus captures step-like, Gaussian-like, and parabolic as well as asymptotically hyperbolic profile shapes. It is expected that this form factor is particularly useful in a model-dependent analysis of small-angle scattering data since the applied continuous and analytical function for the particle density profile can be compared directly with the density profile extracted from the data by model-free approaches like the generalized inverse Fourier transform method. © 2011 American Chemical Society

  8. Developing a scale for quality of life in pediatric oncology patients aged 7-12--children and parent forms.

    PubMed

    Kudubes, Asli Akdeniz; Bektas, Murat

    2015-01-01

    This study was planned in an attempt to develop a scale for the quality of life in pediatric oncology patients aged 7-12, with child and parents forms. In collecting the study data, we used the Child and Parent Information Form, Visual Quality of Life Scale, Scale for Quality of Life Pediatric Oncology Patients Aged 7-12 and the Scale for the Quality of Life in Pediatric Oncology Patients Aged 7-12 for Parents. We also used Pearson correlation analysis, the Cronbach alpha coefficient, factor analysis and ROC analysis for the study data. In this study, the total Cronbach alpha value of the parent form was 0.96, the total factor load being 0.54-0.90 and the total variance explained was 82.5%. The cutoff point of the parent form was 93 points. The total Cronbach alpha value for the child form was 0.96, with a total factor load of 0.55-0.91 and the total variance being explained was 78.3%. The cutoff point of the child form was 65 points. This study suggests that the Scale for Quality of Life in Pediatric Oncology Patients Aged 7-12 Child and Parents Forms are valid and reliable instruments in assessing the quality of life of children.

  9. A Plasma Protein Indistinguishable from Ribosomal Protein S19

    PubMed Central

    Semba, Umeko; Chen, Jun; Ota, Yoshihiko; Jia, Nan; Arima, Hidetoshi; Nishiura, Hiroshi; Yamamoto, Tetsuro

    2010-01-01

    A monocyte-chemoattracting factor is generated during blood coagulation and during clotting of platelet-rich plasma. This chemotactic factor attracts monocytes as a ligand of the C5a receptor; however, it inhibits C5a-induced neutrophil chemotaxis as an apparent receptor antagonist. The curious dual function of the serum monocyte chemotactic factor resembles that of the cross-linked homodimer of ribosomal protein S19 (RP S19). Indeed, the inactive precursor of the monocyte chemotactic factor was present in plasma, and the precursor molecule and RP S19, as well as the active form and the RP S19 dimer, were indistinguishable in terms of immunological reactivity and molecular size. Coagulation factor XIIIa, plasma transglutaminase, and membrane phosphatidylserine on the activated platelets were required for conversion of the precursor to the active form. In addition, the precursor molecule in plasma could be replaced by wild-type recombinant RP S19 but not by mutant forms of it. These results indicate that a molecule indistinguishable from RP S19 was present in plasma, and that the RP S19-like molecule was converted to the active form by a transglutaminase-catalyzed reaction on a scaffold that included the phosphatidylserine-exposed platelet membrane. PMID:20093496

  10. Evaluating the performance of free-formed surface parts using an analytic network process

    NASA Astrophysics Data System (ADS)

    Qian, Xueming; Ma, Yanqiao; Liang, Dezhi

    2018-03-01

    To successfully design parts with a free-formed surface, the critical issue of how to evaluate and select a favourable evaluation strategy before design is raised. The evaluation of free-formed surface parts is a multiple criteria decision-making (MCDM) problem that requires the consideration of a large number of interdependent factors. The analytic network process (ANP) is a relatively new MCDM method that can systematically deal with all kinds of dependences. In this paper, the factors, which come from the life-cycle and influence the design of free-formed surface parts, are proposed. After analysing the interdependence among these factors, a Hybrid ANP (HANP) structure for evaluating the part’s curved surface is constructed. Then, a HANP evaluation of an impeller is presented to illustrate the application of the proposed method.

  11. Proton and neutron electromagnetic form factors and uncertainties

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ye, Zhihong; Arrington, John; Hill, Richard J.

    We determine the nucleon electromagnetic form factors and their uncertainties from world electron scattering data. The analysis incorporates two-photon exchange corrections, constraints on the low-Q 2 and high-Q 2 behavior, and additional uncertainties to account for tensions between different data sets and uncertainties in radiative corrections.

  12. Δ(1232) axial charge and form factors from lattice QCD.

    PubMed

    Alexandrou, Constantia; Gregory, Eric B; Korzec, Tomasz; Koutsou, Giannis; Negele, John W; Sato, Toru; Tsapalis, Antonios

    2011-09-30

    We present the first calculation on the Δ axial vector and pseudoscalar form factors using lattice QCD. Two Goldberger-Treiman relations are derived and examined. A combined chiral fit is performed to the nucleon axial charge, N to Δ axial transition coupling constant and Δ axial charge.

  13. Proton and neutron electromagnetic form factors and uncertainties

    DOE PAGES

    Ye, Zhihong; Arrington, John; Hill, Richard J.; ...

    2017-12-06

    We determine the nucleon electromagnetic form factors and their uncertainties from world electron scattering data. The analysis incorporates two-photon exchange corrections, constraints on the low-Q 2 and high-Q 2 behavior, and additional uncertainties to account for tensions between different data sets and uncertainties in radiative corrections.

  14. Proton Form Factor Puzzle and the CEBAF Large Acceptance Spectrometer (CLAS) Two-Photon Exchange Experiment

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rimal, Dipak

    2014-05-01

    The electromagnetic form factors are the most fundamental observables that encode information about the internal structure of the nucleon. This dissertation explored dependence of R on kinematic variables such as squared four-momentum transfer (Q 2) and the virtual photon polarization parameter (ε).

  15. 48 CFR 315.204-5 - Part IV-Representations and instructions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... as using too few.) (3) Examples of topics that form a basis for evaluation factors. Typical examples of topics that form a basis for the development of evaluation factors are listed in the following... special research, test, and other equipment or facilities. (vii) Managerial capability (ability to achieve...

  16. 48 CFR 315.204-5 - Part IV-Representations and instructions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... as using too few.) (3) Examples of topics that form a basis for evaluation factors. Typical examples of topics that form a basis for the development of evaluation factors are listed in the following... special research, test, and other equipment or facilities. (vii) Managerial capability (ability to achieve...

  17. 48 CFR 315.204-5 - Part IV-Representations and instructions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... as using too few.) (3) Examples of topics that form a basis for evaluation factors. Typical examples of topics that form a basis for the development of evaluation factors are listed in the following... special research, test, and other equipment or facilities. (vii) Managerial capability (ability to achieve...

  18. Probabilistic Multi-Factor Interaction Model for Complex Material Behavior

    NASA Technical Reports Server (NTRS)

    Abumeri, Galib H.; Chamis, Christos C.

    2010-01-01

    Complex material behavior is represented by a single equation of product form to account for interaction among the various factors. The factors are selected by the physics of the problem and the environment that the model is to represent. For example, different factors will be required for each to represent temperature, moisture, erosion, corrosion, etc. It is important that the equation represent the physics of the behavior in its entirety accurately. The Multi-Factor Interaction Model (MFIM) is used to evaluate the divot weight (foam weight ejected) from the external launch tanks. The multi-factor has sufficient degrees of freedom to evaluate a large number of factors that may contribute to the divot ejection. It also accommodates all interactions by its product form. Each factor has an exponent that satisfies only two points - the initial and final points. The exponent describes a monotonic path from the initial condition to the final. The exponent values are selected so that the described path makes sense in the absence of experimental data. In the present investigation, the data used were obtained by testing simulated specimens in launching conditions. Results show that the MFIM is an effective method of describing the divot weight ejected under the conditions investigated. The problem lies in how to represent the divot weight with a single equation. A unique solution to this problem is a multi-factor equation of product form. Each factor is of the following form (1 xi/xf)ei, where xi is the initial value, usually at ambient conditions, xf the final value, and ei the exponent that makes the curve represented unimodal that meets the initial and final values. The exponents are either evaluated by test data or by technical judgment. A minor disadvantage may be the selection of exponents in the absence of any empirical data. This form has been used successfully in describing the foam ejected in simulated space environmental conditions. Seven factors were required to represent the ejected foam. The exponents were evaluated by least squares method from experimental data. The equation is used and it can represent multiple factors in other problems as well; for example, evaluation of fatigue life, creep life, fracture toughness, and structural fracture, as well as optimization functions. The software is rather simplistic. Required inputs are initial value, final value, and an exponent for each factor. The number of factors is open-ended. The value is updated as each factor is evaluated. If a factor goes to zero, the previous value is used in the evaluation.

  19. A comparison of the mechanical, kinetic, and biochemical properties of fibrin clots formed with two different fibrin sealants.

    PubMed

    Hickerson, William L; Nur, Israel; Meidler, Roberto

    2011-01-01

    The objective of the present study was to compare the mechanical, kinetic, and biochemical properties of fibrin clots produced using EVICEL Fibrin Sealant (Human) and TISSEEL Fibrin Sealant. The stiffness/elasticity and strength of fibrin clots formed with EVICEL and TISSEEL were assessed using applied mechanical force and thromboelastography (TEG). The factor XIII content of the fibrin clots was also evaluated. Mean Young modulus and tensile strength of the fibrin clots produced by EVICEL were significantly higher than those of clots produced by TISSEEL (P < 0.05 for both). The mean time to initial clot formation and mean time to the predefined level of clot formation were numerically shorter for EVICEL compared with TISSEEL. Furthermore, mean maximal amplitude of the clots formed with EVICEL was significantly greater than that for the clots formed with TISSEEL. Mean concentration of factor XIII for the EVICEL fibrinogen samples tested was 9 IU/ml compared with undetectable concentrations of factor XIII for the TISSEEL fibrinogen samples. Fibrin clots formed with EVICEL have a much higher resistance to stretching and tensile strength and are more capable of maintaining their structure against applied force than those formed with TISSEEL. EVICEL also allows more rapid development of fibrin clots than TISSEEL. This superior clot strength and resilience obtained with EVICEL relative to TISSEEL may be due in large part to the presence of factor XIII.

  20. Comparison of Factorization-Based Filtering for Landing Navigation

    NASA Technical Reports Server (NTRS)

    McCabe, James S.; Brown, Aaron J.; DeMars, Kyle J.; Carson, John M., III

    2017-01-01

    This paper develops and analyzes methods for fusing inertial navigation data with external data, such as data obtained from an altimeter and a star camera. The particular filtering techniques are based upon factorized forms of the Kalman filter, specifically the UDU and Cholesky factorizations. The factorized Kalman filters are utilized to ensure numerical stability of the navigation solution. Simulations are carried out to compare the performance of the different approaches along a lunar descent trajectory using inertial and external data sources. It is found that the factorized forms improve upon conventional filtering techniques in terms of ensuring numerical stability for the investigated landing navigation scenario.

  1. The factor structure and construct validity of the inventory of callous-unemotional traits in Chinese undergraduate students

    PubMed Central

    Gao, Yu; Deng, Jiaxin; Lai, Hongyu; Deng, Qiaowen; Armour, Cherie

    2017-01-01

    The current study assesses the factor structure and construct validity of the self-reported Inventory of Callous–Unemotional Traits (ICU) in 637 Chinese community adults (mean age = 25.98, SD = 5.79). A series of theoretical models proposed in previous studies were tested through confirmatory factor analyses. Results indicated that a shortened form that consists of 11 items (ICU-11) to assess callousness and uncaring factors has excellent overall fit. Additionally, correlations with a wide range of external variables demonstrated that this shortened form has similar construct validity compared to the original ICU. In conclusion, our findings suggest that the ICU-11 may be a promising self-report tool that could be a good substitute for the original form to assess callous-uncaring traits in adults. PMID:29216240

  2. Calibration for single multi-mode fiber digital scanning microscopy imaging system

    NASA Astrophysics Data System (ADS)

    Yin, Zhe; Liu, Guodong; Liu, Bingguo; Gan, Yu; Zhuang, Zhitao; Chen, Fengdong

    2015-11-01

    Single multimode fiber (MMF) digital scanning imaging system is a development tendency of modern endoscope. We concentrate on the calibration method of the imaging system. Calibration method comprises two processes, forming scanning focused spots and calibrating the couple factors varied with positions. Adaptive parallel coordinate algorithm (APC) is adopted to form the focused spots at the multimode fiber (MMF) output. Compare with other algorithm, APC contains many merits, i.e. rapid speed, small amount calculations and no iterations. The ratio of the optics power captured by MMF to the intensity of the focused spots is called couple factor. We setup the calibration experimental system to form the scanning focused spots and calculate the couple factors for different object positions. The experimental result the couple factor is higher in the center than the edge.

  3. Risk Factors for Gambling Problems on Online Electronic Gaming Machines, Race Betting and Sports Betting

    PubMed Central

    Hing, Nerilee; Russell, Alex M.; Browne, Matthew

    2017-01-01

    Growth of Internet gambling has fuelled concerns about its contribution to gambling problems. However, most online gamblers also gamble on land-based forms, which may be the source of problems for some. Studies therefore need to identify the problematic mode of gambling (online or offline) to identify those with an online gambling problem. Identifying most problematic form of online gambling (e.g., EGMs, race betting, sports betting) would also enable a more accurate examination of gambling problems attributable to a specific online gambling form. This study pursued this approach, aiming to: (1) determine demographic, behavioral and psychological risk factors for gambling problems on online EGMs, online sports betting and online race betting; (2) compare the characteristics of problematic online gamblers on each of these online forms. An online survey of 4,594 Australian gamblers measured gambling behavior, most problematic mode and form of gambling, gambling attitudes, psychological distress, substance use, help-seeking, demographics and problem gambling status. Problem/moderate risk gamblers nominating an online mode of gambling as their most problematic, and identifying EGMs (n = 98), race betting (n = 291) or sports betting (n = 181) as their most problematic gambling form, were compared to non-problem/low risk gamblers who had gambled online on these forms in the previous 12 months (n = 64, 1145 and 1213 respectively), using bivariate analyses and then logistic regressions. Problem/moderate risk gamblers on each of these online forms were then compared. Risk factors for online EGM gambling were: more frequent play on online EGMs, substance use when gambling, and higher psychological distress. Risk factors for online sports betting were being male, younger, lower income, born outside of Australia, speaking a language other than English, more frequent sports betting, higher psychological distress, and more negative attitudes toward gambling. Risk factors for online race betting comprised being male, younger, speaking a language other than English, more frequent race betting, engaging in more gambling forms, self-reporting as semi-professional/professional gambler, illicit drug use whilst gambling, and more negative attitude toward gambling. These findings can inform improved interventions tailored to the specific characteristics of high risk gamblers on each of these online activities. PMID:28555121

  4. Risk Factors for Gambling Problems on Online Electronic Gaming Machines, Race Betting and Sports Betting.

    PubMed

    Hing, Nerilee; Russell, Alex M; Browne, Matthew

    2017-01-01

    Growth of Internet gambling has fuelled concerns about its contribution to gambling problems. However, most online gamblers also gamble on land-based forms, which may be the source of problems for some. Studies therefore need to identify the problematic mode of gambling (online or offline) to identify those with an online gambling problem. Identifying most problematic form of online gambling (e.g., EGMs, race betting, sports betting) would also enable a more accurate examination of gambling problems attributable to a specific online gambling form. This study pursued this approach, aiming to: (1) determine demographic, behavioral and psychological risk factors for gambling problems on online EGMs, online sports betting and online race betting; (2) compare the characteristics of problematic online gamblers on each of these online forms. An online survey of 4,594 Australian gamblers measured gambling behavior, most problematic mode and form of gambling, gambling attitudes, psychological distress, substance use, help-seeking, demographics and problem gambling status. Problem/moderate risk gamblers nominating an online mode of gambling as their most problematic, and identifying EGMs ( n = 98), race betting ( n = 291) or sports betting ( n = 181) as their most problematic gambling form, were compared to non-problem/low risk gamblers who had gambled online on these forms in the previous 12 months ( n = 64, 1145 and 1213 respectively), using bivariate analyses and then logistic regressions. Problem/moderate risk gamblers on each of these online forms were then compared. Risk factors for online EGM gambling were: more frequent play on online EGMs, substance use when gambling, and higher psychological distress. Risk factors for online sports betting were being male, younger, lower income, born outside of Australia, speaking a language other than English, more frequent sports betting, higher psychological distress, and more negative attitudes toward gambling. Risk factors for online race betting comprised being male, younger, speaking a language other than English, more frequent race betting, engaging in more gambling forms, self-reporting as semi-professional/professional gambler, illicit drug use whilst gambling, and more negative attitude toward gambling. These findings can inform improved interventions tailored to the specific characteristics of high risk gamblers on each of these online activities.

  5. Dirac and Pauli form factors of nucleons using nonlocal chiral effective Lagrangian

    NASA Astrophysics Data System (ADS)

    He, Fangcheng; Wang, Ping

    2017-11-01

    Dirac and Pauli form factors are investigated in the relativistic chiral effective Lagrangian. The octet and decuplet intermediate states are included in the one-loop calculation. The 4-dimensional regulator is introduced to deal with the divergence. Different from the non-relativistic case, this 4-dimensional regulator is generated from the nonlocal Lagrangian with the gauge link, which guarantees local gauge invariance. As a result, additional diagrams appear which ensure electric charge 1 and 0 for proton and neutron respectively. The obtained Dirac and Pauli form factors of the nucleons are all reasonable up to relatively large Q 2. Supported by National Natural Science Foundation of China (11475186) and Sino-German CRC 110 (NSFC 11621131001)

  6. On the ππ continuum in the nucleon form factors and the proton radius puzzle

    NASA Astrophysics Data System (ADS)

    Hoferichter, M.; Kubis, B.; Ruiz de Elvira, J.; Hammer, H.-W.; Meißner, U.-G.

    2016-11-01

    We present an improved determination of the ππ continuum contribution to the isovector spectral functions of the nucleon electromagnetic form factors. Our analysis includes the most up-to-date results for the ππ→bar{N} N partial waves extracted from Roy-Steiner equations, consistent input for the pion vector form factor, and a thorough discussion of isospin-violating effects and uncertainty estimates. As an application, we consider the ππ contribution to the isovector electric and magnetic radii by means of sum rules, which, in combination with the accurately known neutron electric radius, are found to slightly prefer a small proton charge radius.

  7. The γγ Physics Program at BESIII

    NASA Astrophysics Data System (ADS)

    Redmer, C. F.

    2018-01-01

    A key motivation for the two-photon physics program of the BESIII collaboration is the need of high precision data on electromagnetic transition form factors as input to the calculations of the contribution of hadronic Light-by-light scattering to the anomalous magnetic moment of the muon. The data collected with the BESIII detector allow to study the momentum dependence of the form factors at small momentum transfers, which is of special relevance for αμ. In this presentation the ongoing measurements of the transition form factors of π0,η and η' mesons, as well as pion pairs, are discussed, and the potential for first double-tagged measurements at BESIII are pointed out.

  8. Confirming the Structural Validity of the My Class Inventory -- Short Form Revised

    ERIC Educational Resources Information Center

    Mariani, Melissa; Villares, Elizabeth; Sink, Christopher A.; Colvin, Kimberly; Kuba, Summer Perhay

    2015-01-01

    Researchers analyzed data collected from elementary school students (N = 893) to further establish the psychometric soundness of the My Class Inventory--Short Form Revised (MCI-SFR). A confirmatory factor analysis was conducted resulting in a good fit for a four-factor model, which corresponds to the instrument's four scales (Cohesion,…

  9. Measurement of the transition form factor of {eta} meson with WASA-at-COSY

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bhatt, H.

    2011-10-24

    Reaction {eta}{yields}e{sup +}e{sup -}{gamma} is used to investigate the transition form factor of {eta} meson with WASA detector at COSY. Where the {eta} meson is produced in pp collision at 1.4 GeV. We present the analysis techniques and preliminary results of {eta} Dalitz decays.

  10. Factor Structure Consistency in the Bruininks-Oseretsky Test--Short Form.

    ERIC Educational Resources Information Center

    Broadhead, Geoffrey D.; Bruininks, Robert H.

    1983-01-01

    The underlying structure of the motor abilities represented by the "Short Form of the Bruininks-Oseretsky Test of Motor Proficiency," along with the consistency of the emerging factors by sex and two chronological age (CA) levels, were studied with 765 nondisabled children 4.6 to 14.6 years old. (Author/SEW)

  11. Familiarity with Content and Syllogistic Reasoning.

    ERIC Educational Resources Information Center

    Mast, Terrill A.; And Others

    Forty-four education and 44 dental students were administered a 30-item syllogism test containing five syllogic forms six times repeated in three different content forms--technical dental terms, common dental terms, and content-free (letters). Data were analyzed using a two-factor with repeated measures on one factor design. It was found that…

  12. Assessing reliability of short and tick box forms of the ANU-ADRI: Convenient alternatives of a self-report Alzheimer's disease risk assessment.

    PubMed

    Kim, Sarang; Cherbuin, Nicolas; Anstey, Kaarin J

    2016-06-01

    To assess the reliability of short versions of the Australian National University Alzheimer's Disease Risk Index (ANU-ADRI). A short form of the ANU-ADRI (ANU-ADRI-SF) was developed by assessing risk and protective factors with single questions where possible and with short forms of sub-questionnaires where available. The tick box form of the ANU-ADRI (ANU-ADRI-TB) was developed with unique questions for each risk and protective factor for Alzheimer's disease. The short versions were evaluated in an independent community sample of 504 participants with a mean age of 45.01 (SD = 14.85, range = 18-81). The short versions demonstrated high reliabilities when compared with the ANU-ADRI. However, the proportion of misclassification was high for some risk factors and particularly for the ANU-ADRI-TB. The ANU-ADRI-SF may be considered if less reliable questions from the ANU-ADRI-SF can be replaced with more reliable questions from the ANU-ADRI for risk/protective factors with high misclassification.

  13. Lattice calculation of electric dipole moments and form factors of the nucleon

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Abramczyk, M.; Aoki, S.; Blum, T.

    In this paper, we analyze commonly used expressions for computing the nucleon electric dipole form factors (EDFF)more » $$F_3$$ and moments (EDM) on a lattice and find that they lead to spurious contributions from the Pauli form factor $$F_2$$ due to inadequate definition of these form factors when parity mixing of lattice nucleon fields is involved. Using chirally symmetric domain wall fermions, we calculate the proton and the neutron EDFF induced by the CP-violating quark chromo-EDM interaction using the corrected expression. In addition, we calculate the electric dipole moment of the neutron using a background electric field that respects time translation invariance and boundary conditions, and we find that it decidedly agrees with the new formula but not the old formula for $$F_3$$. In conclusion, we analyze some selected lattice results for the nucleon EDM and observe that after the correction is applied, they either agree with zero or are substantially reduced in magnitude, thus reconciling their difference from phenomenological estimates of the nucleon EDM.« less

  14. [Clinical manifestations of neurocysticercosis].

    PubMed

    San-juan Orta, D

    2009-06-01

    Cysticercosis is a common parasitic infection caused by the larval phase of the Taenia solium, it infects humans as well as pigs. Considered an endemic parasitosis in developing countries including Latin America, Asia and Africa. Clinical manifestations of the disease can be influenced by ambient factors, host individualities and the infectious agent itself. Neurocysticercosis can be asymptomatic or present with various signs and symptoms that can vary in severity. This review is focused on analyzing the various presentations of Neurocysticercosis throughout different age groups, and special populations. We found asymptomatic presentations to be the most common form, followed by various grades of severity including in its most severe form death. The most common alterations include: epilepsy (60-90%), intracraneal hypertension (14-27%), as well as neuropsychiatric symptoms (5-52%), and focal neurological deficits (4-19%). The heterogeneity of the clinical scenario relies upon parasite factors (number, localization and stage of central nervous system [CNS] disease), host particularities (gender, age and immunologic response), and finally environmental factors. The most common form of infection is asymptomatic although there are various forms of clinical manifestations that rely upon different factors including environment, host response and the parasite itself.

  15. Form factors and differential branching ratio of B →K μ+μ- in AdS/QCD

    NASA Astrophysics Data System (ADS)

    Momeni, S.; Khosravi, R.

    2018-03-01

    The holographic distribution amplitudes (DAs) for the K pseudoscalar meson are derived. For this aim, the light-front wave function (LFWF) of the K meson is extracted within the framework of the anti-de Sitter/quantum chromodynamics (AdS/QCD) correspondence. We consider a momentum-dependent (dynamical) helicity wave function that contains the dynamical spin effects. We use the LFWF to predict the radius and the electromagnetic form factor of the kaon and compare them with the experimental values. Then, the holographic twist-2 DA of K meson ϕK(α ,μ ) is investigated and compared with the result of the light-cone sum rules (LCSR). The transition form factors of the semileptonic B →K ℓ+ℓ- decays are derived from the holographic DAs of the kaon. With the help of these form factors, the differential branching ratio of the B →K μ+μ- on q2 is plotted. A comparison is made between our prediction in AdS/QCD and the results obtained from two models including the LCSR and the lattice QCD as well as the experimental values.

  16. Lattice calculation of electric dipole moments and form factors of the nucleon

    DOE PAGES

    Abramczyk, M.; Aoki, S.; Blum, T.; ...

    2017-07-10

    In this paper, we analyze commonly used expressions for computing the nucleon electric dipole form factors (EDFF)more » $$F_3$$ and moments (EDM) on a lattice and find that they lead to spurious contributions from the Pauli form factor $$F_2$$ due to inadequate definition of these form factors when parity mixing of lattice nucleon fields is involved. Using chirally symmetric domain wall fermions, we calculate the proton and the neutron EDFF induced by the CP-violating quark chromo-EDM interaction using the corrected expression. In addition, we calculate the electric dipole moment of the neutron using a background electric field that respects time translation invariance and boundary conditions, and we find that it decidedly agrees with the new formula but not the old formula for $$F_3$$. In conclusion, we analyze some selected lattice results for the nucleon EDM and observe that after the correction is applied, they either agree with zero or are substantially reduced in magnitude, thus reconciling their difference from phenomenological estimates of the nucleon EDM.« less

  17. Tumor necrosis factor alpha converting enzyme: an encouraging target for various inflammatory disorders.

    PubMed

    Bahia, Malkeet S; Silakari, Om

    2010-05-01

    Tumor necrosis factor alpha is one of the most common pro-inflammatory cytokines responsible for various inflammatory disorders. It plays an important role in the origin and progression of rheumatoid arthritis and also in other autoimmune disease conditions. Some anti-tumor necrosis factor alpha antibodies like Enbrel, Humira and Remicade have been successfully used in these disease conditions as antagonists of tumor necrosis factor alpha. Inhibition of generation of active form of tumor necrosis factor alpha is a promising therapy for various inflammatory disorders. Therefore, the inhibition of an enzyme (tumor necrosis factor alpha converting enzyme), which is responsible for processing inactive form of tumor necrosis factor alpha into its active soluble form, is an encouraging target. Many tumor necrosis factor alpha converting enzyme inhibitors have been the candidates of clinical trials but none of them have reached in to the market because of their broad spectrum inhibitory activity for other matrix metalloproteases. Selectivity of tumor necrosis factor alpha converting enzyme inhibition over matrix metalloproteases is of utmost importance. If selectivity is achieved successfully, side-effects can be over-ruled and this approach may become a novel therapy for treatment of rheumatoid arthritis and other inflammatory disorders. This cytokine not only plays a pivotal role in inflammatory conditions but also in some cancerous conditions. Thus, successful targeting of tumor necrosis factor alpha converting enzyme may result in multifunctional therapy.

  18. Comment on “Breakdown of the expansion of finite-size corrections to the hydrogen Lamb shift in moments of charge distribution”

    DOE PAGES

    Arrington, J.

    2016-02-23

    In a recent study, Hagelstein and Pascalutsa [F. Hagelstein and V. Pascalutsa, Phys. Rev. A 91, 040502 (2015)] examine the error associated with an expansion of proton structure corrections to the Lamb shift in terms of moments of the charge distribution. They propose a small modification to a conventional parametrization of the proton's charge form factor and show that this can resolve the proton radius puzzle. However, while the size of the bump they add to the form factor is small, it is large compared to the total proton structure effects in the initial parametrization, yielding a final form factormore » that is unphysical. Reducing their modification to the point where the resulting form factor is physical does not allow for a resolution of the radius puzzle.« less

  19. Development of a Short Form of the Five-Factor Narcissism Inventory: the FFNI-SF.

    PubMed

    Sherman, Emily D; Miller, Joshua D; Few, Lauren R; Campbell, W Keith; Widiger, Thomas A; Crego, Cristina; Lynam, Donald R

    2015-09-01

    The Five-Factor Narcissism Inventory (FFNI; Glover, Miller, Lynam, Crego, & Widiger, 2012) is a 148-item self-report inventory of 15 traits designed to assess the basic elements of narcissism from the perspective of a 5-factor model. The FFNI assesses both vulnerable (i.e., cynicism/distrust, need for admiration, reactive anger, and shame) and grandiose (i.e., acclaim seeking, arrogance, authoritativeness, entitlement, exhibitionism, exploitativeness, grandiose fantasies, indifference, lack of empathy, manipulativeness, and thrill seeking) variants of narcissism. The present study reports the development of a short-form version of the FFNI in 4 diverse samples (i.e., 2 undergraduate samples, a sample recruited from MTurk, and a clinical community sample) using item response theory. The validity of the resultant 60-item short form was compared against the validity of the full scale in the 4 samples at both the subscale level and the level of the grandiose and vulnerable composites. Results indicated that the 15 subscales remain relatively reliable, possess a factor structure identical to the structure of the long-form scales, and manifest correlational profiles highly similar to those of the long-form scales in relation to a variety of criterion measures, including basic personality dimensions, other measures of grandiose and vulnerable narcissism, and indicators of externalizing and internalizing psychopathology. Grandiose and vulnerable composites also behave almost identically across the short- and long-form versions. It is concluded that the FFNI-Short Form (FFNI-SF) offers a well-articulated assessment of the basic traits comprising grandiose and vulnerable narcissism, particularly when assessment time is limited. (c) 2015 APA, all rights reserved.

  20. A novel form of the RelA nuclear factor kappaB subunit is induced by and forms a complex with the proto-oncogene c-Myc.

    PubMed Central

    Chapman, Neil R; Webster, Gill A; Gillespie, Peter J; Wilson, Brian J; Crouch, Dorothy H; Perkins, Neil D

    2002-01-01

    Members of both Myc and nuclear factor kappaB (NF-kappaB) families of transcription factors are found overexpressed or inappropriately activated in many forms of human cancer. Furthermore, NF-kappaB can induce c-Myc gene expression, suggesting that the activities of these factors are functionally linked. We have discovered that both c-Myc and v-Myc can induce a previously undescribed, truncated form of the RelA(p65) NF-kappaB subunit, RelA(p37). RelA(p37) encodes the N-terminal DNA binding and dimerization domain of RelA(p65) and would be expected to function as a trans-dominant negative inhibitor of NF-kappaB. Surprisingly, we found that RelA(p37) no longer binds to kappaB elements. This result is explained, however, by the observation that RelA(p37), but not RelA(p65), forms a high-molecular-mass complex with c-Myc. These results demonstrate a previously unknown functional and physical interaction between RelA and c-Myc with many significant implications for our understanding of the role that both proteins play in the molecular events underlying tumourigenesis. PMID:12027803

  1. Tensor form factor for the D → π(K) transitions with Twisted Mass fermions.

    NASA Astrophysics Data System (ADS)

    Lubicz, Vittorio; Riggio, Lorenzo; Salerno, Giorgio; Simula, Silvano; Tarantino, Cecilia

    2018-03-01

    We present a preliminary lattice calculation of the D → π and D → K tensor form factors fT (q2) as a function of the squared 4-momentum transfer q2. ETMC recently computed the vector and scalar form factors f+(q2) and f0(q2) describing D → π(K)lv semileptonic decays analyzing the vector current and the scalar density. The study of the weak tensor current, which is directly related to the tensor form factor, completes the set of hadronic matrix element regulating the transition between these two pseudoscalar mesons within and beyond the Standard Model where a non-zero tensor coupling is possible. Our analysis is based on the gauge configurations produced by the European Twisted Mass Collaboration with Nf = 2 + 1 + 1 flavors of dynamical quarks. We simulated at three different values of the lattice spacing and with pion masses as small as 210 MeV and with the valence heavy quark in the mass range from ≃ 0.7 mc to ≃ 1.2mc. The matrix element of the tensor current are determined for a plethora of kinematical conditions in which parent and child mesons are either moving or at rest. As for the vector and scalar form factors, Lorentz symmetry breaking due to hypercubic effects is clearly observed in the data. We will present preliminary results on the removal of such hypercubic lattice effects.

  2. Charge symmetry breaking effects in pion and kaon structure

    NASA Astrophysics Data System (ADS)

    Hutauruk, Parada T. P.; Bentz, Wolfgang; Cloët, Ian C.; Thomas, Anthony W.

    2018-05-01

    Charge symmetry breaking (CSB) effects associated with the u and d quark mass difference are investigated in the quark distribution functions and spacelike electromagnetic form factors of the pion and kaon. We use a confining version of the Nambu-Jona-Lasinio model, where CSB effects at the infrared scale associated with the model are driven by the dressed u and d quark mass ratio, which because of dynamical chiral symmetry breaking is much closer to unity than the associated current quark mass ratio. The pion and kaon are given as bound states of a dressed quark and a dressed antiquark governed by the Bethe-Salpeter equation, and exhibit the properties of Goldstone bosons, with a pion mass difference given by mπ+2-mπ0 2∝(mu-md)2 as demanded by dynamical chiral symmetry breaking. We find significant CSB effects for realistic current quark mass ratios (mu/md˜0.5 ) in the quark flavor-sector electromagnetic form factors of both the pion and kaon. For example, the difference between the u and d quark contributions to the π+ electromagnetic form factors is about 8% at a momentum transfer of Q2≃10 GeV2 , while the analogous effect for the light quark sector form factors in the K+ and K0 is about twice as large. For the parton distribution functions we find CSB effects which are considerably smaller than those found in the electromagnetic form factors.

  3. Study of the in-medium nucleon electromagnetic form factors using a light-front nucleon wave function combined with the quark-meson coupling model

    NASA Astrophysics Data System (ADS)

    de Araújo, W. R. B.; de Melo, J. P. B. C.; Tsushima, K.

    2018-02-01

    We study the nucleon electromagnetic (EM) form factors in symmetric nuclear matter as well as in vacuum within a light-front approach using the in-medium inputs calculated by the quark-meson coupling model. The same in-medium quark properties are used as those used for the study of in-medium pion properties. The zero of the proton EM form factor ratio in vacuum, the electric to magnetic form factor ratio μpGEp (Q2) /GMp (Q2) (Q2 = -q2 > 0 with q being the four-momentum transfer), is determined including the latest experimental data by implementing a hard constituent quark component in the nucleon wave function. A reasonable fit is achieved for the ratio μpGEp (Q2) /GMp (Q2) in vacuum, and we predict that the Q02 value to cross the zero of the ratio to be about 15 GeV2. In addition the double ratio data of the proton EM form factors in 4He and H nuclei, [GEp4He (Q2) /G4HeMp (Q2) ] / [GEp1H (Q2) /GMp1H (Q2) ], extracted by the polarized (e → ,e‧ p →) scattering experiment on 4He at JLab, are well described. We also predict that the Q02 value satisfying μpGEp (Q02) /GMp (Q0 2) = 0 in symmetric nuclear matter, shifts to a smaller value as increasing nuclear matter density, which reflects the facts that the faster falloff of GEp (Q2) as increasing Q2 and the increase of the proton mean-square charge radius. Furthermore, we calculate the neutron EM form factor double ratio in symmetric nuclear matter for 0.1

  4. Textual Enhancement of Two L2 Arabic Forms: A Classroom-Based Study

    ERIC Educational Resources Information Center

    Park, Eun Sung; Nassif, Lama

    2014-01-01

    Research on textual enhancement (TE) has given rise to several factors that may play a role in generating learners' noticing of target forms, one of which pertains to the nature of the target form(s). In particular, results have suggested that learners are more likely to notice more meaning-bearing forms than less meaning-bearing forms.…

  5. Factor structure and reliability of the childhood trauma questionnaire and prevalence estimates of trauma for male and female street youth.

    PubMed

    Forde, David R; Baron, Stephen W; Scher, Christine D; Stein, Murray B

    2012-01-01

    This study examines the psychometric properties of the Childhood Trauma Questionnaire short form (CTQ-SF) with street youth who have run away or been expelled from their homes (N = 397). Internal reliability coefficients for the five clinical scales ranged from .65 to .95. Confirmatory Factor Analysis (CFA) was used to test the five-factor structure of the scales yielding acceptable fit for the total sample. Additional multigroup analyses were performed to consider items by gender. Results provided only evidence of weak factorial invariance. Constrained models showed invariance in configuration, factor loadings, and factor covariances but failed for equality of intercepts. Mean trauma scores for street youth tended to fall in the moderate to severe range on all abuse/neglect clinical scales. Females reported higher levels of abuse and neglect. Prevalence of child maltreatment of individual forms was very high with 98% of street youth reporting one or more forms; 27.4% of males and 48.9% of females reported all five forms. Results of this study support the viability of the CTQ-SF for screening maltreatment in a highly vulnerable street population. Caution is recommended when comparing prevalence estimates for male and female street youth given the failure of the strong factorial multigroup model.

  6. Development and Examination of the Five-Factor Obsessive-Compulsive Inventory-Short Form.

    PubMed

    Griffin, Sarah A; Suzuki, Takakuni; Lynam, Donald R; Crego, Cristina; Widiger, Thomas A; Miller, Joshua D; Samuel, Douglas B

    2018-01-01

    The Five-Factor Obsessive-Compulsive Inventory (FFOCI) is an assessment of obsessive-compulsive personality disorder (OCPD) that is based on the conceptual framework of the five-factor model (FFM) of personality. The FFOCI has 12 subscales that assess those five-factor model facets relevant to the description of OCPD. Research has suggested that the FFOCI scores relate robustly to existing measures of OCPD and relevant scales from general personality inventories. Nonetheless, the FFOCI's length-120 items-may limit its clinical utility. This study derived a 48-item FFOCI-Short Form (FFOCI-SF) from the original measure using item response theory methods. The FFOCI-SF scales successfully recreated the nomological network of the original measure and improved discriminant validity relative to the long form. These results support the use of the FFOCI-SF as a briefer measure of the lower-order traits associated with OCPD.

  7. An Evaluation of FrancoForme: A CASE-MANAGED HOME-BASED PRIMARY AND SECONDARY CARDIOVASCULAR DISEASE PREVENTION PROGRAM FOR FRENCH-SPEAKING CANADIANS.

    PubMed

    Prince, Stephanie A; Laflamme, Marc; Harris, Jennifer; Tulloch, Heather E; de Margerie, Michele

    2017-11-01

    Cardiovascular disease (CVD) is the leading cause of mortality globally. Telephone-delivered interventions targeting cardiovascular risk factors are gaining popularity. This study is an evaluation of FrancoForme, a cardiovascular risk factor reduction program for the primary and secondary prevention of CVD among French-speaking patients of Eastern Ontario. This study reports on changes in cardiovascular risk factors, weekly exercise levels, and psychosocial characteristics including anxiety, depression, and quality of life upon program completion (3 months) and at 1 year after the start of the program. Repeated-measures analysis of variance was used to compare changes in outcomes between primary prevention risk groups (low, moderate, and high risk for CVD) and the secondary prevention group (ie, cardiac rehabilitation) at baseline, 3 months and 12 months. A total of 762 patients enrolled in FrancoForme between 2008 and 2015. At 3 months, all program completers (n = 507) experienced significant reductions for all cardiovascular risk factors except diastolic blood pressure. Minutes of self-reported exercise increased significantly by an average 90 minutes per week and all psychosocial variables improved. Significant group effects were observed across several risk factors. Among 12-month responders (n = 240), exercise, high-density lipoproteins, triglycerides, cholesterol, and all psychosocial variables were improved over baseline results. FrancoForme is unique in targeting both the primary and secondary prevention of CVD and removes several of the barriers to participating in a conventional CVD prevention program for French-speaking patients. FrancoForme is successful, receiving high satisfaction rates and resulting in significant improvements in cardiovascular risk factors, exercise, anxiety, and depression, as well as quality of life.

  8. Abnormal factor VIII coagulant antigen in patients with renal dysfunction and in those with disseminated intravascular coagulation.

    PubMed Central

    Weinstein, M J; Chute, L E; Schmitt, G W; Hamburger, R H; Bauer, K A; Troll, J H; Janson, P; Deykin, D

    1985-01-01

    Factor VIII antigen (VIII:CAg) exhibits molecular weight heterogeneity in normal plasma. We have compared the relative quantities of VIII:CAg forms present in normal individuals (n = 22) with VIII:CAg forms in renal dysfunction patients (n = 19) and in patients with disseminated intravascular coagulation (DIC; n = 7). In normal plasma, the predominant VIII: CAg form, detectable by sodium dodecyl sulfate polyacrylamide gel electrophoresis, was of molecular weight 2.4 X 10(5), with minor forms ranging from 8 X 10(4) to 2.6 X 10(5) D. A high proportion of VIII:CAg in renal dysfunction patients, in contrast, was of 1 X 10(5) mol wt. The patients' high 1 X 10(5) mol wt VIII: CAg level correlated with increased concentrations of serum creatinine, F1+2 (a polypeptide released upon prothrombin activation), and with von Willebrand factor. Despite the high proportion of the 1 X 10(5) mol wt VIII:CAg form, which suggests VIII:CAg proteolysis, the ratio of Factor VIII coagulant activity to total VIII:CAg concentration was normal in renal dysfunction patients. These results could be simulated in vitro by thrombin treatment of normal plasma, which yielded similar VIII:CAg gel patterns and Factor VIII coagulant activity to antigen ratios. DIC patients with high F1+2 levels but no evidence of renal dysfunction had an VIII:CAg gel pattern distinct from renal dysfunction patients. DIC patients had elevated concentrations of both the 1 X 10(5) and 8 X 10(4) mol wt VIII:CAg forms. We conclude that an increase in a particular VIII:CAg form correlates with the severity of renal dysfunction. The antigen abnormality may be the result of VIII:CAg proteolysis by a thrombinlike enzyme and/or prolonged retention of proteolyzed VIII:CAg fragments. Images PMID:3932466

  9. Purification and Properties of Myxococcus xanthus C-Factor, an Intercellular Signaling Protein

    NASA Astrophysics Data System (ADS)

    Kim, Seung K.; Kaiser, Dale

    1990-05-01

    C-factor, a Myxococcus xanthus protein that restores the developmental defects of a class of nonautonomous mutants resulting from mutation of the csgA gene, has been purified approximately 1000-fold from starved wild-type cells. The monomeric form of C-factor is a single polypeptide with a molecular mass of 17 kDa that can be solubilized by detergent from membrane components. Characterization by gel filtration and denaturing gel electrophoresis suggests that biologically active C-factor is a dimer composed of two 17-kDa monomers. Antibodies against a form of the M. xanthus csgA gene product overexpressed in Escherichia coli react with purified C-factor.

  10. Ab initio simulations of the dynamic ion structure factor of warm dense lithium

    DOE PAGES

    Witte, B. B. L.; Shihab, M.; Glenzer, S. H.; ...

    2017-04-06

    Here, we present molecular dynamics simulations based on finite-temperature density functional theory that determine self-consistently the dynamic ion structure factor and the electronic form factor in lithium. Our comprehensive data set allows for the calculation of the dispersion relation for collective excitations, the calculation of the sound velocity, and the determination of the ion feature from the total electronic form factor and the ion structure factor. The results are compared with available experimental x-ray and neutron scattering data. Good agreement is found for both the liquid metal and warm dense matter domain. Finally, we study the impact of possible targetmore » inhomogeneities on x-ray scattering spectra.« less

  11. Ab initio simulations of the dynamic ion structure factor of warm dense lithium

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Witte, B. B. L.; Shihab, M.; Glenzer, S. H.

    Here, we present molecular dynamics simulations based on finite-temperature density functional theory that determine self-consistently the dynamic ion structure factor and the electronic form factor in lithium. Our comprehensive data set allows for the calculation of the dispersion relation for collective excitations, the calculation of the sound velocity, and the determination of the ion feature from the total electronic form factor and the ion structure factor. The results are compared with available experimental x-ray and neutron scattering data. Good agreement is found for both the liquid metal and warm dense matter domain. Finally, we study the impact of possible targetmore » inhomogeneities on x-ray scattering spectra.« less

  12. Exploratory Bi-factor Analysis: The Oblique Case.

    PubMed

    Jennrich, Robert I; Bentler, Peter M

    2012-07-01

    Bi-factor analysis is a form of confirmatory factor analysis originally introduced by Holzinger and Swineford (Psychometrika 47:41-54, 1937). The bi-factor model has a general factor, a number of group factors, and an explicit bi-factor structure. Jennrich and Bentler (Psychometrika 76:537-549, 2011) introduced an exploratory form of bi-factor analysis that does not require one to provide an explicit bi-factor structure a priori. They use exploratory factor analysis and a bifactor rotation criterion designed to produce a rotated loading matrix that has an approximate bi-factor structure. Among other things this can be used as an aid in finding an explicit bi-factor structure for use in a confirmatory bi-factor analysis. They considered only orthogonal rotation. The purpose of this paper is to consider oblique rotation and to compare it to orthogonal rotation. Because there are many more oblique rotations of an initial loading matrix than orthogonal rotations, one expects the oblique results to approximate a bi-factor structure better than orthogonal rotations and this is indeed the case. A surprising result arises when oblique bi-factor rotation methods are applied to ideal data.

  13. Measuring childhood abuse and neglect in a group of female indoor sex workers in the Netherlands: a confirmatory factor analysis of the Dutch version of the Childhood Trauma Questionnaire-Short Form.

    PubMed

    Daalder, Annelies L; Bogaerts, Stefan

    2011-06-01

    Confirmatory factor analysis was performed on the responses to the Dutch version of the Childhood Trauma Questionnaire-Short Form from a sample of 123 female indoor sex workers in The Netherlands. Results indicate the expected five-factor structure fit the data well. In line with Bernstein and others, the instrument was a valid measure of retrospective childhood abuse and neglect in this sample.

  14. Absorptive corrections for vector mesons: matching to complex mass scheme and longitudinal corrections

    NASA Astrophysics Data System (ADS)

    Jiménez Pérez, L. A.; Toledo Sánchez, G.

    2017-12-01

    Unstable spin-1 particles are properly described by including absorptive corrections to the electromagnetic vertex and propagator, without breaking the electromagnetic gauge invariance. We show that the modified propagator can be set in a complex mass form, provided the mass and width parameters, which are properly defined at the pole, are replaced by energy dependent functions fulfilling the same requirements at the pole. We exemplify the case for the {K}* (892) vector meson, and find that the mass function deviates around 2 MeV from the Kπ threshold to the pole, and that the width function exhibits a different behavior compared to the uncorrected energy dependent width. Considering the {τ }-\\to {K}{{S}}{π }-{ν }τ decay as dominated by the {K}* (892) and {K}{\\prime * }(1410) vectors and one scalar particle, we exhibit the role of the transversal and longitudinal corrections to the vector propagator by obtaining the modified vector and scalar form factors. The modified vector form factor is found to be the same as in the complex mass form, while the scalar form factor receives a modification from the longitudinal correction to the vector propagator. A fit to the experimental Kπ spectrum shows that the phase induced by the presence of this new contribution in the scalar sector improves the description of the experimental data in the troublesome region around 0.7 GeV. Besides that, the correction to the scalar form factor is found to be negligible.

  15. A comparative analysis of salivary factors and maxillary denture retention in different arch forms: An in vivo study.

    PubMed

    Shekhar, Abhishek; Das, Samiran; Bhattacharyya, Jayanta; Goel, Preeti; Majumdar, Sayan; Ghosh, Soumitra

    2018-01-01

    This study aims to find the effect of change in different salivary factors before and after complete denture insertion and to measure the maxillary denture retention in different arch forms. Thirty completely edentulous individuals (10 each of square, tapered, and ovoid arch form of maxilla) belonging to the age group of 40-70 years were selected. Salivary factors (flow, density, pH, viscosity, and total protein) were evaluated before and after denture insertion. Retention of maxillary denture was measured in all the different arch forms. Student's independent sample's t -test was applied. The correlation was analyzed by Pearson's correlation analysis. While mean flow rate and pH of saliva increased, mean viscosity, total protein, and density of saliva decreased after maxillary complete denture insertion. A positive correlation was found between retention and total maxillary basal surface area. Retention value was found to be greatest in square type and least in tapered type. Complete denture acts as a mechanical stimulant thus increasing flow rate and pH immediately after complete denture insertion. Density, total protein, and viscosity of saliva decreased after complete denture insertion which may be due to increase in water content of saliva. The retention of maxillary complete denture does not seem to depend on the rate of change of the salivary factors, before and after complete denture insertion. Total basal surface area and maxillary denture retention values were highest in square arch form and least in tapered arch form.

  16. Two distinct forms of Factor VIII coagulant protein in human plasma. Cleavage by thrombin, and differences in coagulant activity and association with von Willebrand factor.

    PubMed Central

    Weinstein, M J; Chute, L E

    1984-01-01

    We have characterized Factor VIII coagulant protein, present in normal human plasma, that reacts with a specific human 125I-labeled anti-human VIII:C antigen Fab antibody fragment. Two major Factor VIII coagulant antigen populations were present. The first, approximately 85% of the total antigen, was bound to von Willebrand factor and when tested in a standard one-stage assay had Factor VIII coagulant activity. The second antigenic population, eluting near fibrinogen when plasma was gel filtered, was not bound to von Willebrand protein, did not have Factor VIII coagulant activity unless activated, but did block anti-VIII:C Fab neutralization of clotting activity. The two antigenic populations were separable by cryoprecipitation and agarose gel electrophoresis. Although the two antigenic populations differed in their Factor VIII coagulant activity and in their binding to von Willebrand factor, the principal member of both populations is of mol wt 2.4 X 10(5). Both antigens, when proteolyzed by thrombin, were quickly converted to a 1 X 10(5)-mol wt form in association with the appearance of VIII:C activity. The 1 X 10(5)-mol wt antigen was further slowly degraded to an 8 X 10(4)-mol wt form while Factor VIII coagulant activity declined. These results demonstrate the presence of an inactive Factor VIII coagulant protein in plasma, not associated with von Willebrand factor, that can react with thrombin to yield Factor VIII coagulant activity. Images PMID:6421875

  17. Site and stand factors affecting height growth curves of longleaf pine plantations

    Treesearch

    William D. Boyer

    1981-01-01

    Abstract Some factors related to the form of height-over- age curves in longleaf pine plantations were identified from analyses of 660 periodically remeasured plots.Seventy percent of the variation among 32 plantations in form the growth curve was accounted for by stratifying planting sites into old fields, mechanically prepared and unprepared cut-...

  18. Regulation of LPS-induced tissue factor expression in human monocytic THP-1 cells by curcumin

    USDA-ARS?s Scientific Manuscript database

    Tissue factor (TF) is a transmembrane receptor, which initiates thrombotic episodes associated with various diseases. In addition to membrane-bound TF, we have discovered an alternatively spliced form of human TF mRNA. It was later confirmed that this form of TF mRNA expresses a soluble protein circ...

  19. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wally Melnitchouk; John Tjon

    We compute the corrections from two-photon and \\gamma-Z exchange in parity-violating elastic electron--proton scattering, used to extract the strange form factors of the proton. We use a hadronic formalism that successfully reconciled the earlier discrepancy in the proton's electron to magnetic form factor ratio, suitably extended to the weak sector. Implementing realistic electroweak form factors, we find effects of the order 2-3% at Q^2 <~ 0.1 GeV^2, which are largest at backward angles, and have a strong Q^2 dependence at low Q^2. Two-boson contributions to the weak axial current are found to be enhanced at low Q^2 and for forwardmore » angles. We provide corrections at kinematics relevant for recent and upcoming parity-violating experiments.« less

  20. D → Klv semileptonic decay using lattice QCD with HISQ at physical pion masses

    NASA Astrophysics Data System (ADS)

    Chakraborty, Bipasha; Davies, Christine; Koponen, Jonna; Lepage, G. Peter

    2018-03-01

    he quark flavor sector of the Standard Model is a fertile ground to look for new physics effects through a unitarity test of the Cabbibo-Kobayashi-Maskawa (CKM) matrix. We present a lattice QCD calculation of the scalar and the vector form factors (over a large q2 region including q2 = 0) associated with the D→ Klv semi-leptonic decay. This calculation will then allow us to determine the central CKM matrix element, Vcs in the Standard Model, by comparing the lattice QCD results for the form factors and the experimental decay rate. This form factor calculation has been performed on the Nf = 2 + 1 + 1 MILC HISQ ensembles with the physical light quark masses.

  1. Asymptotic behaviour of two-point functions in multi-species models

    NASA Astrophysics Data System (ADS)

    Kozlowski, Karol K.; Ragoucy, Eric

    2016-05-01

    We extract the long-distance asymptotic behaviour of two-point correlation functions in massless quantum integrable models containing multi-species excitations. For such a purpose, we extend to these models the method of a large-distance regime re-summation of the form factor expansion of correlation functions. The key feature of our analysis is a technical hypothesis on the large-volume behaviour of the form factors of local operators in such models. We check the validity of this hypothesis on the example of the SU (3)-invariant XXX magnet by means of the determinant representations for the form factors of local operators in this model. Our approach confirms the structure of the critical exponents obtained previously for numerous models solvable by the nested Bethe Ansatz.

  2. 75 FR 9918 - Agency Information Collection Activities: Proposed Collection; Comment Request, 1660-0006...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-04

    ... Endorsement; FEMA Form 086-0-5, Flood Insurance Preferred Risk Policy Application; FEMA Form 086-0-4, V-Zone Risk Factor Rating Form and Instructions. SUMMARY: The Federal Emergency Management Agency, as part of... Application; FEMA Form 086-0- [[Page 9919

  3. Measuring Alexithymia via Trait Approach-I: A Alexithymia Scale Item Selection and Formation of Factor Structure

    PubMed Central

    TATAR, Arkun; SALTUKOĞLU, Gaye; ALİOĞLU, Seda; ÇİMEN, Sümeyye; GÜVEN, Hülya; AY, Çağla Ebru

    2017-01-01

    Introduction It is not clear in the literature whether available instruments are sufficient to measure alexithymia because of its theoretical structure. Moreover, it has been reported that several measuring instruments are needed to measure this construct, and all the instruments have different error sources. The old and the new forms of Toronto Alexithymia Scale are the only instruments available in Turkish. Thus, the purpose of this study was to develop a new scale to measure alexithymia, selecting items and constructing the factor structure. Methods A total of 1117 patients aged from 19 to 82 years (mean = 35.05 years) were included. A 100-item pool was prepared and applied to 628 women and 489 men. Data were analyzed using Explanatory Factor Analysis, Confirmatory Factor Analysis, and Item Response Theory and 28 items were selected. The new form of 28 items was applied to 415 university students, including 271 women and 144 men aged from 18 to 30 (mean=21.44). Results The results of Explanatory Factor Analysis revealed a five-factor construct of “Solving and Expressing Affective Experiences,” “External Locused Cognitive Style,” “Tendency to Somatize Affections,” “Imaginary Life and Visualization,” and “Acting Impulsively,” along with a two-factor construct representing the “Affective” and “Cognitive” components. All the components of the construct showed good model fit and high internal consistency. The new form was tested in terms of internal consistency, test-retest reliability, and concurrent validity using Toronto Alexithymia Scale as criteria and discriminative validity using Five-Factor Personality Inventory Short Form. Conclusion The results showed that the new scale met the basic psychometric requirements. Results have been discussed in line with related studies. PMID:29033633

  4. Factor structure and criterion validity across the full scale and ten short forms of the CES-D among Chinese adolescents.

    PubMed

    Yang, Wenhui; Xiong, Ge; Garrido, Luis Eduardo; Zhang, John X; Wang, Meng-Cheng; Wang, Chong

    2018-04-16

    We systematically examined the factor structure and criterion validity across the full scale and 10 short forms of the Center for Epidemiological Studies Depression Scale (CES-D) with Chinese youth. Participants were 5,434 Chinese adolescents in Grades 7 to 12 who completed the full CES-D; 612 of them further completed a structured diagnostic interview with the major depressive disorder (MDD) module of the Kiddie Schedule for Affective Disorder and Schizophrenia for School-age Children. Using a split-sample approach, a series of 4-, 3-, 2-, and 1-factor models were tested using exploratory structural equation modeling and cross-validated using confirmatory factor analysis; the dimensionality was also evaluated by parallel analysis in conjunction with the scree test and aided by factor mixture analysis. The results indicated that a single-factor model of depression with a wording method factor fitted the data well, and was the optimal structure underlying the scores of the full and shortened CES-D. Additionally, receiver operating characteristic curve analyses for MDD case detection showed that the CES-D full-scale scores accurately detected MDD youth (area under the curve [AUC] = .84). Furthermore, the short-form scores produced comparable AUCs with the full scale (.82 to .85), as well as similar levels of sensitivity and specificity when using optimal cutoffs. These findings suggest that depression among Chinese adolescents can be adequately measured and screened for by a single-factor structure underlying the CES-D scores, and that the short forms provide a viable alternative to the full instrument. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  5. Zinc-induced Self-association of Complement C3b and Factor H

    PubMed Central

    Nan, Ruodan; Tetchner, Stuart; Rodriguez, Elizabeth; Pao, Po-Jung; Gor, Jayesh; Lengyel, Imre; Perkins, Stephen J.

    2013-01-01

    The sub-retinal pigment epithelial deposits that are a hallmark of age-related macular degeneration contain both C3b and millimolar levels of zinc. C3 is the central protein of complement, whereas C3u is formed by the spontaneous hydrolysis of the thioester bridge in C3. During activation, C3 is cleaved to form active C3b, then C3b is inactivated by Factor I and Factor H to form the C3c and C3d fragments. The interaction of zinc with C3 was quantified using analytical ultracentrifugation and x-ray scattering. C3, C3u, and C3b associated strongly in >100 μm zinc, whereas C3c and C3d showed weak association. With zinc, C3 forms soluble oligomers, whereas C3u and C3b precipitate. We conclude that the C3, C3u, and C3b association with zinc depended on the relative positions of C3d and C3c in each protein. Computational predictions showed that putative weak zinc binding sites with different capacities exist in all five proteins, in agreement with experiments. Factor H forms large oligomers in >10 μm zinc. In contrast to C3b or Factor H alone, the solubility of the central C3b-Factor H complex was much reduced at 60 μm zinc and even more so at >100 μm zinc. The removal of the C3b-Factor H complex by zinc explains the reduced C3u/C3b inactivation rates by zinc. Zinc-induced precipitation may contribute to the initial development of sub-retinal pigment epithelial deposits in the retina as well as reducing the progression to advanced age-related macular degeneration in higher risk patients. PMID:23661701

  6. 78 FR 46418 - Proposed Information Collection (Obligation To Report Factors Affecting Entitlement) Activity...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-31

    ... (Obligation To Report Factors Affecting Entitlement) Activity; Comment Request AGENCY: Veterans Benefits... use of other forms of information technology. Title: Obligation to Report Factors Affecting... entitlement factors. Individual factors such as income, marital status, and the beneficiary's number of...

  7. 75 FR 62634 - Proposed Information Collection (Obligation to Report Factors Affecting Entitlement) Activity...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-12

    ... (Obligation to Report Factors Affecting Entitlement) Activity: Comment Request AGENCY: Veterans Benefits... use of other forms of information technology. Title: Obligation to Report Factors Affecting... entitlement factors. Individual factors such as income, marital status, and the beneficiary's number of...

  8. Assessing applicants to the NASA flight program for their renal stone-forming potential

    NASA Technical Reports Server (NTRS)

    Pak, Charles Y. C.; Hill, Kathy; Cintron, Nitza M.; Huntoon, Carolyn

    1989-01-01

    Because spaceflight can provoke the formation of kidney stones, 24-hour urine samples for 104 male applicants were analyzed for stone-forming risk factors prior to their selection into the NASA astronaut-mission specialist corps. A high level of supersaturation (with either calcium oxalate, brushite, or monosodium urate) was noted in these applicants which predisposes them to the crystallization of stone-forming calcium salts. It is suggested that most of the abnormal stone risk factors found were environmental, rather than metabolic, in origin.

  9. The relationship between the content and the form of metaphorical statements.

    PubMed

    Xu, Xu

    2010-04-01

    Recent research suggests that the quality of a metaphorical topic-vehicle pairing should be the determinant to the choice of a proper grammatical form, nominal metaphor versus simile. Two studies examined the relationship between the quality of the content of a metaphorical statement and its grammatical form. Study 1 showed that the two grammatical forms did not differ in aptness when the quality of topic-vehicle pairs and the conventionality of vehicles, a factor associated with the quality of metaphorical expressions, were controlled. With an online comprehension measure, Study 2 found that high quality metaphorical pairings were easier to process than low quality metaphorical pairings in both the metaphor form and the simile form. For high quality metaphorical pairings, information related to both the topics and the vehicles was highly activated at an early stage of processing. The relations among factors involved in the interpretive process of metaphorical language are discussed.

  10. Risk factors for pancreatic stone formation in autoimmune pancreatitis over a long-term course.

    PubMed

    Maruyama, Masahiro; Arakura, Norikazu; Ozaki, Yayoi; Watanabe, Takayuki; Ito, Tetsuya; Yoneda, Suguru; Maruyama, Masafumi; Muraki, Takashi; Hamano, Hideaki; Matsumoto, Akihiro; Kawa, Shigeyuki

    2012-05-01

    Autoimmune pancreatitis (AIP) has the potential to progress to a chronic state that forms pancreatic stones. The aim of this study was to clarify the risk factors underlying pancreatic stone formation in AIP. Sixty-nine patients with AIP who had been followed for at least 3 years were enrolled for evaluation of clinical and laboratory factors as well as computed tomography and endoscopic retrograde cholangiopancreatography findings. During the course of this study, increased or de novo stone formation was seen in 28 patients, who were defined as the stone-forming group. No stones were observed in 32 patients, who were defined as the non-stone-forming group. Nine patients who had stones at diagnosis but showed no change during the course of this study were excluded from our cohort. Univariate analysis revealed no significant differences in clinical or laboratory factors associated with AIP-specific inflammation between the two groups. However, pancreatic head swelling (P = 0.006) and narrowing of both Wirsung's and Santorini's ducts in the pancreatic head region (P = 0.010) were significantly more frequent in the stone-forming group. Furthermore, multivariate analysis identified Wirsung and Santorini duct narrowing at diagnosis as a significant independent risk factor for pancreatic stone formation (OR 4.4, P = 0.019). A primary risk factor for pancreatic stone formation in AIP was narrowing of both Wirsung's and Santorini's ducts, which most presumably led to pancreatic juice stasis and stone development.

  11. Precision Measurement of the proton neutral weak form factors at Q 2 ~ 0.1 GeV 2

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kaufman, Lisa J.

    2007-02-01

    This thesis reports the HAPPEX measurement of the parity-violating asymmetry for longitudinally polarized electrons elastically scattered from protons in a liquid hydrogen target. The measurement was carried out in Hall A at Thomas Jefferson National Accelerator Facility using a beam energy E = 3 GeV and scattering angle = 6°. The asymmetry is sensitive to the weak neutral form factors from which we extract the strange quark electric and magnetic form factors (Gmore » $$s\\atop{E}$$ and G$$s\\atop{M}$$) of the proton. The measurement was conducted during two data-taking periods in 2004 and 2005. This thesis describes the methods for controlling the helicity-correlated beam asymmetries and the analysis of the raw asymmetry. The parity-violating asymmetry has been measured to be A PV = -1.14± 0.24 (stat)±0.06 (syst) ppm at 2> = 0.099 GeV 2 (2004), and A PV = -1.58±0.12 (stat)±0.04 (syst) ppm at 2> = 0.109 GeV 2 (2005). The strange quark form factors extracted from the asymmetry are G$$s\\atop{E}$$ + 0.080G$$s\\atop{M}$$ = 0.030 ± 0.025 (stat) ± 0.006 (syst) ± 0.012 (FF) (2004) and G$$s\\atop{E}$$ +0.088G$$s\\atop{M}$$ = 0.007±0.011 (stat)±0.004 (syst)±0.005 (FF) (2005). These results place the most precise constraints on the strange quark form factors and indicate little strange dynamics in the proton.« less

  12. [Current situations and problem analysis of influencing factors of traditional Chinese medicine tablets on forming quality].

    PubMed

    Li, Yan-Nian; Wu, Zhen-Feng; Wan, Na; Li, Yuan-Hui; Li, Hui-Ting; Yang, Ming

    2018-04-01

    The compressibility of tablets is the essential operating unit during the preparation of traditional Chinese medicine tablets, as well as a complicated process. Therefore, it is of great significance to comprehensively study the influencing factors on the formation process. This paper aimed to review the evaluation methods for the tablet forming quality and highlight the effects of material powder properties, excipients and preparation technology on the quality of traditional Chinese medicine tablets on the basis of relevant literatures. Furthermore, the common problems in tablet forming process are also analyzed to provide useful references for the development of tablet forming quality of traditional Chinese medicines. Copyright© by the Chinese Pharmaceutical Association.

  13. Anthrax toxin: the long and winding road that leads to the kill.

    PubMed

    Abrami, Laurence; Reig, Nuria; van der Goot, F Gisou

    2005-02-01

    The past five years have led to a tremendous increase in our molecular understanding of the mode of action of the anthrax toxin, one of the two main virulence factors produced by Bacillus anthracis. The structures of each of the three components of the toxin--lethal factor (LF), edema factor (EF) and protective antigen (PA)--have been solved not only in their monomeric forms but, depending on the subunit, in a heptameric form, bound to their substrate, co-factor or receptor. The endocytic route followed by the toxin has also been unraveled and the enzymatic mechanisms of EF and LF elucidated.

  14. Flowering phenology, growth forms, and pollination syndromes in tropical dry forest species: Influence of phylogeny and abiotic factors.

    PubMed

    Cortés-Flores, Jorge; Hernández-Esquivel, Karen Beatriz; González-Rodríguez, Antonio; Ibarra-Manríquez, Guillermo

    2017-01-01

    Analyses of the influence of temporal variation in abiotic factors on flowering phenology of tropical dry forest species have not considered the possible response of species with different growth forms and pollination syndromes, while controlling for phylogenetic relationships among species. Here, we investigated the relationship between flowering phenology, abiotic factors, and plant functional attributes, while controlling for phylogenetic relationship among species, in a dry forest community in Mexico. We characterized flowering phenology (time and duration) and pollination syndromes of 55 tree species, 49 herbs, 24 shrubs, 15 lianas, and 11 vines. We tested the influence of pollination syndrome, growth form, and abiotic factors on flowering phenology using phylogenetic generalized least squares. We found a relationship between flowering duration and time. Growth form was related to flowering time, and the pollination syndrome had a more significant relationship with flowering duration. Flowering time variation in the community was explained mainly by abiotic variables, without an important phylogenetic effect. Flowering time in lianas and trees was negatively and positively correlated with daylength, respectively. Functional attributes, environmental cues, and phylogeny interact with each other to shape the diversity of flowering patterns. Phenological differentiation among species groups revealed multiples strategies associated with growth form and pollination syndromes that can be important for understanding species coexistence in this highly diverse plant community. © 2017 Botanical Society of America.

  15. A Validation Study of the Dutch Childhood Trauma Questionnaire-Short Form: Factor Structure, Reliability, and Known-Groups Validity

    ERIC Educational Resources Information Center

    Thombs, Brett D.; Bernstein, David P.; Lobbestael, Jill; Arntz, Arnoud

    2009-01-01

    Objective: The 28-item Childhood Trauma Questionnaire-Short Form (CTQ-SF) has been translated into at least 10 different languages. The validity of translated versions of the CTQ-SF, however, has generally not been examined. The objective of this study was to investigate the factor structure, internal consistency reliability, and known-groups…

  16. Quark Mass Functions and Pion Structure in the Covariant Spectator Theory

    DOE PAGES

    Biernat, Elmar P.; Gross, Franz; Pena, Teresa; ...

    2018-05-24

    The Covariant Spectator Theory is applied to the description of quarks and the pion. The dressed quark mass function is calculated dynamically in Minkowski space and used in the calculation of the pion electromagnetic form factor. The effects of the mass function on the pion form factor and the different quark-pole contributions to the triangle diagram then are analyzed.

  17. Quark Mass Functions and Pion Structure in the Covariant Spectator Theory

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Biernat, Elmar P.; Gross, Franz; Pena, Teresa

    The Covariant Spectator Theory is applied to the description of quarks and the pion. The dressed quark mass function is calculated dynamically in Minkowski space and used in the calculation of the pion electromagnetic form factor. The effects of the mass function on the pion form factor and the different quark-pole contributions to the triangle diagram then are analyzed.

  18. A Factor Analytic Investigation of the BASC-2 Behavioral and Emotional Screening System Parent Form: Psychometric Properties, Practical Implications, and Future Directions

    ERIC Educational Resources Information Center

    Dowdy, Erin; Chin, Jenna K.; Twyford, Jennifer M.; Dever, Bridget V.

    2011-01-01

    The Behavior Assessment System for Children, Second Edition (BASC-2) Behavioral and Emotional Screening System Parent Form (BESS Parent; Kamphaus & Reynolds, 2007) is a recently developed instrument designed to identify behavioral and emotional risk in students. To describe the underlying factor structure for this instrument, exploratory (EFA)…

  19. Validation of the Short Form of the Career Development Inventory with an Iranian High School Sample

    ERIC Educational Resources Information Center

    Sadeghi, Ahmad; Baghban, Iran; Bahrami, Fatemeh; Ahmadi, Ahmad; Creed, Peter

    2011-01-01

    A short 33-item form of the Career Development Inventory was validated on a sample of 310 Iranian high school students. Factor analysis indicated that attitude and cognitive subscale items loaded on their respective factors, and that internal reliability coefficients at all levels were satisfactory to good. Support for validity was demonstrated by…

  20. Central depression of nuclear charge density distribution

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chu Yanyun; Ren Zhongzhou; Center of Theoretical Nuclear Physics, National Laboratory of Heavy-Ion Accelerator, Lanzhou 730000

    The center-depressed nuclear charge distributions are investigated with the parametrized distribution and the relativistic mean-field theory, and their corresponding charge form factors are worked out with the phase shift analysis method. The central depression of nuclear charge distribution of {sup 46}Ar and {sup 44}S is supported by the relativistic mean-field calculation. According to the calculation, the valence protons in {sup 46}Ar and {sup 44}S prefer to occupy the 1d{sub 3/2} state rather than the 2s{sub 1/2} state, which is different from that in the less neutron-rich argon and sulfur isotopes. As a result, the central proton densities of {sup 46}Armore » and {sup 44}S are highly depressed, and so are their central charge densities. The charge form factors of some argon and sulfur isotopes are presented, and the minima of the charge form factors shift upward and inward when the central nuclear charge distributions are more depressed. Besides, the effect of the central depression on the charge form factors is studied with a parametrized distribution, when the root-mean-square charge radii remain constant.« less

  1. Higgs Amplitudes from N=4 Supersymmetric Yang-Mills Theory.

    PubMed

    Brandhuber, Andreas; Kostacińska, Martyna; Penante, Brenda; Travaglini, Gabriele

    2017-10-20

    Higgs plus multigluon amplitudes in QCD can be computed in an effective Lagrangian description. In the infinite top-mass limit, an amplitude with a Higgs boson and n gluons is computed by the form factor of the operator TrF^{2}. Up to two loops and for three gluons, its maximally transcendental part is captured entirely by the form factor of the protected stress tensor multiplet operator T_{2} in N=4 supersymmetric Yang-Mills theory. The next order correction involves the calculation of the form factor of the higher-dimensional, trilinear operator TrF^{3}. We present explicit results at two loops for three gluons, including the subleading transcendental terms derived from a particular descendant of the Konishi operator that contains TrF^{3}. These are expressed in terms of a few universal building blocks already identified in earlier calculations. We show that the maximally transcendental part of this quantity, computed in nonsupersymmetric Yang-Mills theory, is identical to the form factor of another protected operator, T_{3}, in the maximally supersymmetric theory. Our results suggest that the maximally transcendental part of Higgs amplitudes in QCD can be entirely computed through N=4 super Yang-Mills theory.

  2. K π vector form factor, dispersive constraints and τ→ ν τ K π decays

    NASA Astrophysics Data System (ADS)

    Boito, Diogo R.; Escribano, Rafel; Jamin, Matthias

    2009-02-01

    Recent experimental data for the differential decay distribution of the decay τ -→ ν τ K S π - by the Belle collaboration are described by a theoretical model which is composed of the contributing vector and scalar form factors F {+/ K π }( s) and F {0/ K π }( s). Both form factors are constructed such that they fulfil constraints posed by analyticity and unitarity. A good description of the experimental measurement is achieved by incorporating two vector resonances and working with a three-times-subtracted dispersion relation in order to suppress higher-energy contributions. The resonance parameters of the charged K *(892) meson, defined as the pole of F {+/ K π }( s) in the complex s-plane, can be extracted, with the result M_{K^{*}}=892.0± 0.9 MeV and \\varGamma_{K^{*}}=46.2± 0.4 MeV . Finally, employing a three-times-subtracted dispersion relation allows one to determine the slope and curvature parameters λ'+=(24.7±0.8)×10-3 and λ″+=(12.0±0.2)×10-4 of the vector form factor F {+/ K π }( s) directly from the data.

  3. Peripheral transverse densities of the baryon octet from chiral effective field theory and dispersion analysis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Alarcón, J. M.; Hiller Blin, A. N.; Vicente Vacas, M. J.

    2017-05-08

    The baryon electromagnetic form factors are expressed in terms of two-dimensional densities describing the distribution of charge and magnetization in transverse space at fixed light-front time. In this paper, we calculate the transverse densities of the spin-1/2 flavor-octet baryons at peripheral distances b=O(Mmore » $$-1\\atop{π}$$) using methods of relativistic chiral effective field theory (χ EFT) and dispersion analysis. The densities are represented as dispersive integrals over the imaginary parts of the form factors in the timelike region (spectral functions). The isovector spectral functions on the two-pion cut t > 4 M$$2\\atop{π}$$ are calculated using relativistic χEFT including octet and decuplet baryons. The χEFT calculations are extended into the ρ meson mass region using an N/D method that incorporates the pion electromagnetic form factor data. The isoscalar spectral functions are modeled by vector meson poles. We compute the peripheral charge and magnetization densities in the octet baryon states, estimate the uncertainties, and determine the quark flavor decomposition. Finally, the approach can be extended to baryon form factors of other operators and the moments of generalized parton distributions.« less

  4. Role of hepsin in factor VII activation in zebrafish.

    PubMed

    Khandekar, Gauri; Jagadeeswaran, Pudur

    2014-01-01

    Factor VII, the initiator of the extrinsic coagulation cascade, circulates in human plasma mainly in its zymogen form, factor VII and in small amounts in its activated form, factor VIIa. However, the mechanism of initial generation of factor VIIa is not known despite intensive research using currently available model systems. Earlier findings suggested serine proteases factor VII activating protease and hepsin play a role in activating factor VII, however, it has remained controversial. In this paper we estimated the levels of factor VIIa and factor VII for the first time in zebrafish adult population and also reevaluated the role of the above two serine proteases in activating factor VII in vivo using zebrafish as a model system. Knockdown of factor VII activating protease and hepsin was performed followed by assaying for their effect on factor VIIa concentration and extrinsic coagulation as measured by the kinetic prothrombin time. Factor VII activating protease knockdown showed no change in kinetic prothrombin time and no effect on factor VIIa levels while hepsin knockdown increased the kinetic prothrombin time and significantly reduced the factor VIIa plasma levels. Our results thus indicate that hepsin plays a physiologically important role in factor VII activation and hemostasis in zebrafish. © 2013.

  5. The Role of Nerve Growth Factor (NGF) and Its Precursor Forms in Oral Wound Healing

    PubMed Central

    Schenck, Karl; Schreurs, Olav; Hayashi, Katsuhiko; Helgeland, Kristen

    2017-01-01

    Nerve growth factor (NGF) and its different precursor forms are secreted into human saliva by salivary glands and are also produced by an array of cells in the tissues of the oral cavity. The major forms of NGF in human saliva are forms of pro-nerve growth factor (pro-NGF) and not mature NGF. The NGF receptors tropomyosin-related kinase A (TrkA) and p75 neurotrophin receptor (p75NTR) are widely expressed on cells in the soft tissues of the human oral cavity, including keratinocytes, endothelial cells, fibroblasts and leukocytes, and in ductal and acinar cells of all types of salivary glands. In vitro models show that NGF can contribute at most stages in the oral wound healing process: restitution, cell survival, apoptosis, cellular proliferation, inflammation, angiogenesis and tissue remodeling. NGF may therefore take part in the effective wound healing in the oral cavity that occurs with little scarring. As pro-NGF forms appear to be the major form of NGF in human saliva, efforts should be made to study its function, specifically in the process of wound healing. In addition, animal and clinical studies should be initiated to examine if topical application of pro-NGF or NGF can be a therapy for chronic oral ulcerations and wounds. PMID:28208669

  6. The Role of Nerve Growth Factor (NGF) and Its Precursor Forms in Oral Wound Healing.

    PubMed

    Schenck, Karl; Schreurs, Olav; Hayashi, Katsuhiko; Helgeland, Kristen

    2017-02-11

    Nerve growth factor (NGF) and its different precursor forms are secreted into human saliva by salivary glands and are also produced by an array of cells in the tissues of the oral cavity. The major forms of NGF in human saliva are forms of pro-nerve growth factor (pro-NGF) and not mature NGF. The NGF receptors tropomyosin-related kinase A (TrkA) and p75 neurotrophin receptor (p75 NTR ) are widely expressed on cells in the soft tissues of the human oral cavity, including keratinocytes, endothelial cells, fibroblasts and leukocytes, and in ductal and acinar cells of all types of salivary glands. In vitro models show that NGF can contribute at most stages in the oral wound healing process: restitution, cell survival, apoptosis, cellular proliferation, inflammation, angiogenesis and tissue remodeling. NGF may therefore take part in the effective wound healing in the oral cavity that occurs with little scarring. As pro-NGF forms appear to be the major form of NGF in human saliva, efforts should be made to study its function, specifically in the process of wound healing. In addition, animal and clinical studies should be initiated to examine if topical application of pro-NGF or NGF can be a therapy for chronic oral ulcerations and wounds.

  7. Risk factors in adolescence: the case of gambling, videogame playing, and the internet.

    PubMed

    Griffiths, M; Wood, R T

    2000-01-01

    It has been noted that adolescents may be more susceptible to pathological gambling. Not only is it usually illegal, but it appears to be related to high levels of problem gambling and other delinquent activities such as illicit drug taking and alcohol abuse. This paper examines risk factors not only in adolescent gambling but also in videogame playing (which shares many similarities with gambling). There appear to be three main forms of adolescent gambling that have been widely researched. Adolescent gambling activities and general risk factors in adolescent gambling are provided. As well, the influence of technology on adolescents in the form of both videogames and the Internet are examined. It is argued that technologically advanced forms of gambling may be highly appealing to adolescents.

  8. Analysis of the strong coupling form factors of ΣbNB and ΣcND in QCD sum rules

    NASA Astrophysics Data System (ADS)

    Yu, Guo-Liang; Wang, Zhi-Gang; Li, Zhen-Yu

    2017-08-01

    In this article, we study the strong interaction of the vertices Σ b NB and Σ c ND using the three-point QCD sum rules under two different Dirac structures. Considering the contributions of the vacuum condensates up to dimension 5 in the operation product expansion, the form factors of these vertices are calculated. Then, we fit the form factors into analytical functions and extrapolate them into time-like regions, which gives the coupling constants. Our analysis indicates that the coupling constants for these two vertices are G ΣbNB = 0.43±0.01 GeV-1 and G ΣcND = 3.76±0.05 GeV-1. Supported by Fundamental Research Funds for the Central Universities (2016MS133)

  9. Dirac and Pauli form factors from lattice QCD

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Collins, S.; Goeckeler, M.; Nobile, A.

    2011-10-01

    We present a comprehensive analysis of the electromagnetic form factors of the nucleon from a lattice simulation with two flavors of dynamical O(a)-improved Wilson fermions. A key feature of our calculation is that we make use of an extensive ensemble of lattice gauge field configurations with four different lattice spacings, multiple volumes, and pion masses down to m{sub {pi}{approx}1}80 MeV. We find that by employing Kelly-inspired parametrizations for the Q{sup 2} dependence of the form factors, we are able to obtain stable fits over our complete ensemble. Dirac and Pauli radii and the anomalous magnetic moments of the nucleon aremore » extracted and results at light quark masses provide evidence for chiral nonanalytic behavior in these fundamental observables.« less

  10. Chinese version of the Optimism and Pessimism Scale: Psychometric properties in mainland China and development of a short form.

    PubMed

    Xia, Jie; Wu, Daxing; Zhang, Jibiao; Xu, Yuanchao; Xu, Yunxuan

    2016-06-01

    This study aimed to validate the Chinese version of the Optimism and Pessimism Scale in a sample of 730 adult Chinese individuals. Confirmatory factor analyses confirmed the bidimensionality of the scale with two factors, optimism and pessimism. The total scale and optimism and pessimism factors demonstrated satisfactory reliability and validity. Population-based normative data and mean values for gender, age, and education were determined. Furthermore, we developed a 20-item short form of the Chinese version of the Optimism and Pessimism Scale with structural validity comparable to the full form. In summary, the Chinese version of the Optimism and Pessimism Scale is an appropriate and practical tool for epidemiological research in mainland China. © The Author(s) 2014.

  11. Parity Violating electron scattering from Hydrogen and Helium-4 and Strangness in the nucleon: Results from HAPPEX-II

    NASA Astrophysics Data System (ADS)

    Moffit, Bryan

    2006-11-01

    The quark-antiquark pairs that form the sea within the nucleon are well established within quantum chromodynamics. Several recent and ongoing experiments are motivated by determining how this sea, containing contributions from all quark flavors, plays a role in affecting the nucleon's overall properties. Of particular interest is the possible strange quark contribution to the nucleon's electric and magnetic form factors. The recently completed HAPPEX asymmetry measurements take advantage of parity violation in elastic electron scattering to probe the strange quark effects. The measurement using a hydrogen target is sensitive to a linear combination of GE^s and GM^s, the contribution to the electric and magnetic form factors due to strange quarks, respectively, whereas scattering from a spinless helium target cleanly isolates GE^s. The combination of the two measurements therefore allows these form factors to be separately determined. Final results will be presented from the complete data set, obtained in runs in 2004 and 2005, yielding results of unprecedented precision.

  12. Cell-wall deficient L. monocytogenes L-forms feature abrogated pathogenicity

    PubMed Central

    Schnell, Barbara; Staubli, Titu; Harris, Nicola L.; Rogler, Gerhard; Kopf, Manfred; Loessner, Martin J.; Schuppler, Markus

    2014-01-01

    Stable L-forms are cell wall-deficient bacteria which are able to multiply and propagate indefinitely, despite the absence of a rigid peptidoglycan cell wall. We investigated whether L-forms of the intracellular pathogen L. monocytogenes possibly retain pathogenicity, and if they could trigger an innate immune response. While phagocytosis of L. monocytogenes L-forms by non-activated macrophages sometimes resulted in an unexpected persistence of the bacteria in the phagocytes, they were effectively eliminated by IFN-γ preactivated or bone marrow-derived macrophages (BMM). These findings were in line with the observed down-regulation of virulence factors in the cell-wall deficient L. monocytogenes. Absence of Interferon-β (IFN-β) triggering indicated inability of L-forms to escape from the phagosome into the cytosol. Moreover, abrogated cytokine response in MyD88-deficient dendritic cells (DC) challenged with L. monocytogenes L-forms suggested an exclusive TLR-dependent host response. Taken together, our data demonstrate a strong attenuation of Listeria monocytogenes L-form pathogenicity, due to diminished expression of virulence factors and innate immunity recognition, eventually resulting in elimination of L-form bacteria from phagocytes. PMID:24904838

  13. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Horn, Tanja; Roberts, Craig D.

    Quantum chromodynamics (QCDs) is the strongly interacting part of the Standard Model. It is supposed to describe all of nuclear physics; and yet, almost 50 years after the discovery of gluons and quarks, we are only just beginning to understand how QCD builds the basic bricks for nuclei: neutrons and protons, and the pions that bind them together. QCD is characterised by two emergent phenomena: confinement and dynamical chiral symmetry breaking (DCSB). They have far-reaching consequences, expressed with great force in the character of the pion; and pion properties, in turn, suggest that confinement and DCSB are intimately connected. Indeed,more » since the pion is both a Nambu–Goldstone boson and a quark–antiquark bound-state, it holds a unique position in nature and, consequently, developing an understanding of its properties is critical to revealing some very basic features of the Standard Model. We describe experimental progress toward meeting this challenge that has been made using electromagnetic probes, highlighting both dramatic improvements in the precision of charged-pion form factor data that have been achieved in the past decade and new results on the neutral-pion transition form factor, both of which challenge existing notions of pion structure. We also provide a theoretical context for these empirical advances, which begins with an explanation of how DCSB works to guarantee that the pion is un-naturally light; but also, nevertheless, ensures that the pion is the best object to study in order to reveal the mechanisms that generate nearly all the mass of hadrons. In canvassing advances in these areas, our discussion unifies many aspects of pion structure and interactions, connecting the charged-pion elastic form factor, the neutral-pion transition form factor and the pion's leading-twist parton distribution amplitude. It also sketches novel ways in which experimental and theoretical studies of the charged-kaon electromagnetic form factor can provide significant contributions. Importantly, it appears that recent predictions for the large-Q 2 behaviour of the charged-pion form factor can be tested by experiments planned at the upgraded 12 GeV Jefferson Laboratory. Those experiments will extend precise charged-pion form factor data up to momentum transfers that it now appears may be large enough to serve in validating factorisation theorems in QCD. If so, they may expose the transition between the non-perturbative and perturbative domains and thereby reach a goal that has driven hadro-particle physics for around 35 years.« less

  14. The pion: an enigma within the Standard Model

    NASA Astrophysics Data System (ADS)

    Horn, Tanja; Roberts, Craig D.

    2016-07-01

    Quantum chromodynamics (QCDs) is the strongly interacting part of the Standard Model. It is supposed to describe all of nuclear physics; and yet, almost 50 years after the discovery of gluons and quarks, we are only just beginning to understand how QCD builds the basic bricks for nuclei: neutrons and protons, and the pions that bind them together. QCD is characterised by two emergent phenomena: confinement and dynamical chiral symmetry breaking (DCSB). They have far-reaching consequences, expressed with great force in the character of the pion; and pion properties, in turn, suggest that confinement and DCSB are intimately connected. Indeed, since the pion is both a Nambu-Goldstone boson and a quark-antiquark bound-state, it holds a unique position in nature and, consequently, developing an understanding of its properties is critical to revealing some very basic features of the Standard Model. We describe experimental progress toward meeting this challenge that has been made using electromagnetic probes, highlighting both dramatic improvements in the precision of charged-pion form factor data that have been achieved in the past decade and new results on the neutral-pion transition form factor, both of which challenge existing notions of pion structure. We also provide a theoretical context for these empirical advances, which begins with an explanation of how DCSB works to guarantee that the pion is un-naturally light; but also, nevertheless, ensures that the pion is the best object to study in order to reveal the mechanisms that generate nearly all the mass of hadrons. In canvassing advances in these areas, our discussion unifies many aspects of pion structure and interactions, connecting the charged-pion elastic form factor, the neutral-pion transition form factor and the pion's leading-twist parton distribution amplitude. It also sketches novel ways in which experimental and theoretical studies of the charged-kaon electromagnetic form factor can provide significant contributions. Importantly, it appears that recent predictions for the large-Q 2 behaviour of the charged-pion form factor can be tested by experiments planned at the upgraded 12 GeV Jefferson Laboratory. Those experiments will extend precise charged-pion form factor data up to momentum transfers that it now appears may be large enough to serve in validating factorisation theorems in QCD. If so, they may expose the transition between the non-perturbative and perturbative domains and thereby reach a goal that has driven hadro-particle physics for around 35 years.

  15. The Norwegian Computerized Adaptive Test of Personality Disorder-Static Form (CAT-PD-SF): Reliability, Factor Structure, and Relationships With Personality Functioning.

    PubMed

    Thimm, Jens C

    2017-12-01

    The Computerized Adaptive Test of Personality Disorder-Static Form (CAT-PD-SF) is a self-report inventory developed to assess pathological personality traits. The current study explored the reliability and higher order factor structure of the Norwegian version of the CAT-PD-SF and the relationships between the CAT-PD traits and domains of personality functioning in an undergraduate student sample ( N = 375). In addition to the CAT-PD-SF, the short form of the Severity Indices of Personality Problems and the Brief Symptom Inventory were administered. The results showed that the Norwegian CAT-PD-SF has good score reliability. Factor analysis of the CAT-PD-SF scales indicated five superordinate factors that correspond to the trait domains of the alternative DSM-5 model for personality disorders. The CAT-PD traits were highly predictive of impaired personality functioning after controlling for psychological distress. It is concluded that the CAT-PD-SF is a promising tool for the assessment of personality disorder traits.

  16. Construct and Predictive Validity of Social Acceptability: Scores From High School Teacher Ratings on the School Intervention Rating Form

    ERIC Educational Resources Information Center

    Harrison, Judith R.; State, Talida M.; Evans, Steven W.; Schamberg, Terah

    2016-01-01

    The purpose of this study was to evaluate the construct and predictive validity of scores on a measure of social acceptability of class-wide and individual student intervention, the School Intervention Rating Form (SIRF), with high school teachers. Utilizing scores from 158 teachers, exploratory factor analysis revealed a three-factor (i.e.,…

  17. Helicopter Transparent Enclosures. Volume 1. Design Handbook

    DTIC Science & Technology

    1979-01-01

    Armour Research Foundation, "Engineering Design Factors for Laminated Aircraft Windshields, Part 2," WADC-TR-53-99, Wright Air Devel- opment Center...77L~i- -- - -- References .. l,. Islir~ger, Armour Research Foundation, "Engineering Design Factors for Laminated Aircraft Windshields, Parts 1 ahd I...of having separate heating and forming devices, often used with acrylic, will rarely be feasible with polycarbonates. 29.7 Forming Methods Drape

  18. The Short Form of the Five-Factor Narcissism Inventory: Psychometric Equivalence of the Turkish Version

    ERIC Educational Resources Information Center

    Eksi, Füsun

    2016-01-01

    This study intends to examine the psychometric properties of the Turkish version of the short form of the Five-Factor Narcissism Inventory (FFNI-SF). The study group consists of a total of 526 university students (54% were female) whose ages range from 18 to 32. In the translational equivalence study made over a two-week interval, the FFNI-SF…

  19. Exploring Hadron Structure Through Exclusive Kaon Electroproduction

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Carmignotto, Marco A.

    The kaon electroproduction cross section was extracted from data from the E93-018 and the E01-004 (FPI-2) experiments taken at the Thomas Jefferson National Accelerator Facility in the p(e,e'K +)Λ channel. The cross section was fully separated into longitudinal, transverse, and two interference components at four-momentum transfers Q 2 of 1.0 (GeV/c) 2 (with center of mass energy W=1.81 GeV), 1.36 and 2.07 (GeV/c) 2 (W=2.31 GeV). The kaon form factor (FK) was extracted from the longitudinal cross section in these kinematics using the Regge model by Vanderhaeghen, Guidal, and Laget. Results show F K to be systematically lower than themore » empirical monopole form, although still compatible with this form within the estimated uncertainties. The resulting kaon form factor values were combined with the world pion and kaon form factor data to extract the transverse change densities of the pion and kaon. These were compared to that of the proton, showing a possible experimental glimpse of the transition between the proton core and the meson cloud in terms of transverse densities.« less

  20. Stem form changes in upland oaks after thinning

    Treesearch

    Donald E. Hilt; Martin E. Dale

    1979-01-01

    Results of two independent studies were analyzed to determine whether residual stocking after thinning had any effect on change in stem form of upland oak. One study is based on 15 years' change in Girard Form Class after thinning of an 80-year-old white oak stand in eastern Kentucky. The other, 12-year changes in Girard Form Class and breast-height form factor...

  1. Preformulation considerations for controlled release dosage forms. Part III. Candidate form selection using numerical weighting and scoring.

    PubMed

    Chrzanowski, Frank

    2008-01-01

    Two numerical methods, Decision Analysis (DA) and Potential Problem Analysis (PPA) are presented as alternative selection methods to the logical method presented in Part I. In DA properties are weighted and outcomes are scored. The weighted scores for each candidate are totaled and final selection is based on the totals. Higher scores indicate better candidates. In PPA potential problems are assigned a seriousness factor and test outcomes are used to define the probability of occurrence. The seriousness-probability products are totaled and forms with minimal scores are preferred. DA and PPA have never been compared to the logical-elimination method. Additional data were available for two forms of McN-5707 to provide complete preformulation data for five candidate forms. Weight and seriousness factors (independent variables) were obtained from a survey of experienced formulators. Scores and probabilities (dependent variables) were provided independently by Preformulation. The rankings of the five candidate forms, best to worst, were similar for all three methods. These results validate the applicability of DA and PPA for candidate form selection. DA and PPA are particularly applicable in cases where there are many candidate forms and where each form has some degree of unfavorable properties.

  2. Comparing Factor Structures of Adolescent Psychopathology

    ERIC Educational Resources Information Center

    Verona, Edelyn; Javdani, Shabnam; Sprague, Jenessa

    2011-01-01

    Research on the structure of adolescent psychopathology can provide information on broad factors that underlie different forms of maladjustment in youths. Multiple studies from the literature on adult populations suggest that 2 factors, Internalizing and Externalizing, meaningfully comprise the factor structure of adult psychopathology (e.g.,…

  3. The nucleon as a test case to calculate vector-isovector form factors at low energies

    NASA Astrophysics Data System (ADS)

    Leupold, Stefan

    2018-01-01

    Extending a recent suggestion for hyperon form factors to the nucleon case, dispersion theory is used to relate the low-energy vector-isovector form factors of the nucleon to the pion vector form factor. The additionally required input, i.e. the pion-nucleon scattering amplitudes are determined from relativistic next-to-leading-order (NLO) baryon chiral perturbation theory including the nucleons and optionally the Delta baryons. Two methods to include pion rescattering are compared: a) solving the Muskhelishvili-Omnès (MO) equation and b) using an N/D approach. It turns out that the results differ strongly from each other. Furthermore the results are compared to a fully dispersive calculation of the (subthreshold) pion-nucleon amplitudes based on Roy-Steiner (RS) equations. In full agreement with the findings from the hyperon sector it turns out that the inclusion of Delta baryons is not an option but a necessity to obtain reasonable results. The magnetic isovector form factor depends strongly on a low-energy constant of the NLO Lagrangian. If it is adjusted such that the corresponding magnetic radius is reproduced, then the results for the corresponding pion-nucleon scattering amplitude (based on the MO equation) agree very well with the RS results. Also in the electric sector the Delta degrees of freedom are needed to obtain the correct order of magnitude for the isovector charge and the corresponding electric radius. Yet quantitative agreement is not achieved. If the subtraction constant that appears in the solution of the MO equation is not taken from nucleon+Delta chiral perturbation theory but adjusted such that the electric radius is reproduced, then one obtains also in this sector a pion-nucleon scattering amplitude that agrees well with the RS results.

  4. B → Dℓν form factors at nonzero recoil and |V cb| from 2+1-flavor lattice QCD

    DOE PAGES

    Bailey, Jon A.

    2015-08-10

    We present the first unquenched lattice-QCD calculation of the hadronic form factors for the exclusive decay B¯→Dℓν¯ at nonzero recoil. We carry out numerical simulations on 14 ensembles of gauge-field configurations generated with 2+1 flavors of asqtad-improved staggered sea quarks. The ensembles encompass a wide range of lattice spacings (approximately 0.045 to 0.12 fm) and ratios of light (up and down) to strange sea-quark masses ranging from 0.05 to 0.4. For the b and c valence quarks we use improved Wilson fermions with the Fermilab interpretation, while for the light valence quarks we use asqtad-improved staggered fermions. We extrapolate ourmore » results to the physical point using rooted staggered heavy-light meson chiral perturbation theory. We then parametrize the form factors and extend them to the full kinematic range using model-independent functions based on analyticity and unitarity. We present our final results for f +(q 2) and f 0(q 2), including statistical and systematic errors, as coefficients of a series in the variable z and the covariance matrix between these coefficients. We then fit the lattice form-factor data jointly with the experimentally measured differential decay rate from BABAR to determine the CKM matrix element, |V cb|=(39.6 ± 1.7 QCD+exp ± 0.2 QED) × 10 –3. As a byproduct of the joint fit we obtain the form factors with improved precision at large recoil. In conclusion, we use them to update our calculation of the ratio R(D) in the Standard Model, which yields R(D)=0.299(11).« less

  5. Investigation of the laser engineered net shaping process for nanostructured cermets

    NASA Astrophysics Data System (ADS)

    Xiong, Yuhong

    Laser Engineered Net Shaping (LENSRTM) is a solid freeform fabrication (SFF) technology that combines high power laser deposition and powder metallurgy technologies. The LENSRTM technology has been used to fabricate a number of metallic alloys with improved physical and mechanical material properties. The successful application provides a motivation to also apply this method to fabricate non-metallic alloys, such as tungsten carbide-cobalt (WC-Co) cermets in a timely and easy way. However, reports on this topic are very limited. In this work, the LENSRTM technology was used to investigate its application to nanostructured WC-Co cermets, including processing conditions, microstructural evolution, thermal behavior, mechanical properties, and environmental and economic benefits. Details of the approaches are described as follows. A comprehensive analysis of the relationships between process parameters, microstructural evolution and mechanical properties was conducted through various analytical techniques. Effects of process parameters on sample profiles and microstructures were analyzed. Dissolution, shape change and coarsening of WC particles were investigated to study the mechanisms of microstructural evolution. The thermal features were correlated with the microstructure and mechanical properties. The special thermal behavior during this process and its relevant effects on the microstructure have been experimentally studied and numerically simulated. A high-speed digital camera was applied to study the temperature profile, temperature gradient and cooling rate in and near the molten pool. Numerical modeling was employed for 3D samples using finite element method with ADINA software for the first time. The validated modeling results were used to interpret microstructural evolution and thermal history. In order to fully evaluate the capability of the LENSRTM technology for the fabrication of cermets, material properties of WC-Co cermets produced by different powder metallurgy technologies were compared. In addition, another cermet system, nanostructured titanium/tungsten carbide-nickel ((Ti,W)C-Ni) powder, prepared using high-energy ball milling process, was also deposited by the LENSRTM technology. Because of the near net shape feature of the LENSRTM process, special emphasis was also placed on its potential environmental and economic benefits by applying life cycle assessment (LCA) and technical cost modeling (TCM). Comparisons were conducted between the conventional powder metallurgy processes and the LENSRTM process.

  6. Reducing psychological distress and obesity in Australian farmers by promoting physical activity

    PubMed Central

    2011-01-01

    Background Studies have confirmed that the rate of mental illness is no higher in rural Australians than that of urban Australians. However, the rate of poor mental health outcomes, and in particular suicide, is significantly raised in rural populations. This is thought to be due to lack of early diagnosis, health service access, the distance-decay effect, poor physical health determinants and access to firearms. Research conducted by the National Centre for Farmer Health between 2004 and 2009 reveals that there is a correlation between obesity and psychological distress among the farming community where suicide rates are recognised as high. Chronic stress overstimulates the regulation of the hypothalamic-pituitary-adrenal (HPA) axis that is associated with abdominal obesity. Increasing physical activity may block negative thoughts, increase social contact, positively influence brain chemistry and improve both physical and mental health. This paper describes the design of the Farming Fit study that aims to identify the effect of physical activity on psychological distress, obesity and health behaviours such as diet patterns and smoking in farm men and women. Methods/Design For this quasi-experimental (convenience sample) control-intervention study, overweight (Body Mass Index ≥25 kg/m2) farm men and women will be recruited from Sustainable Farm Families™ (SFF) programs held across Victoria, Australia. Baseline demographic data, health data, depression anxiety stress scale (DASS) scores, dietary information, physical activity data, anthropometric data, blood pressure and biochemical analysis of plasma and salivary cortisol levels will be collected. The intervention group will receive an exercise program and regular phone coaching in order to increase their physical activity. Analysis will evaluate the impact of the intervention by longitudinal data (baseline and post intervention) comparison of intervention and control groups. Discussion This study is designed to examine the effect of physical activity on psychological health and other co-morbidities such as obesity, impaired glucose tolerance, hypertension and dyslipidaemia within a high-risk cohort. The outcomes of this research will be relevant to further research and service delivery programs, in particular those tailored to rural communities. Trial registration ACTRN12610000827033 PMID:21600058

  7. Reducing psychological distress and obesity in Australian farmers by promoting physical activity.

    PubMed

    Brumby, Susan; Chandrasekara, Ananda; McCoombe, Scott; Torres, Susan; Kremer, Peter; Lewandowski, Paul

    2011-05-23

    Studies have confirmed that the rate of mental illness is no higher in rural Australians than that of urban Australians. However, the rate of poor mental health outcomes, and in particular suicide, is significantly raised in rural populations. This is thought to be due to lack of early diagnosis, health service access, the distance-decay effect, poor physical health determinants and access to firearms. Research conducted by the National Centre for Farmer Health between 2004 and 2009 reveals that there is a correlation between obesity and psychological distress among the farming community where suicide rates are recognised as high. Chronic stress overstimulates the regulation of the hypothalamic-pituitary-adrenal (HPA) axis that is associated with abdominal obesity. Increasing physical activity may block negative thoughts, increase social contact, positively influence brain chemistry and improve both physical and mental health. This paper describes the design of the Farming Fit study that aims to identify the effect of physical activity on psychological distress, obesity and health behaviours such as diet patterns and smoking in farm men and women. For this quasi-experimental (convenience sample) control-intervention study, overweight (Body Mass Index ≥25 kg/m(2)) farm men and women will be recruited from Sustainable Farm Families™ (SFF) programs held across Victoria, Australia. Baseline demographic data, health data, depression anxiety stress scale (DASS) scores, dietary information, physical activity data, anthropometric data, blood pressure and biochemical analysis of plasma and salivary cortisol levels will be collected. The intervention group will receive an exercise program and regular phone coaching in order to increase their physical activity. Analysis will evaluate the impact of the intervention by longitudinal data (baseline and post intervention) comparison of intervention and control groups. This study is designed to examine the effect of physical activity on psychological health and other co-morbidities such as obesity, impaired glucose tolerance, hypertension and dyslipidaemia within a high-risk cohort. The outcomes of this research will be relevant to further research and service delivery programs, in particular those tailored to rural communities. ACTRN12610000827033.

  8. Endogenous digitalis-like factors.

    PubMed

    Schoner, W

    1992-01-01

    The postulate of a natriuretic factor inhibiting the sodium pump in the kidney led to the detection of increased concentrations of endogenous digitalis-like factors in blood after salt loading, in essential hypertension, in pregnancy-induced hypertension and in chronic hypervolaemia. The recent isolation of ouabain or a close isomer thereof from human plasma and the demonstration of a compound similar if not identical to digoxin in adrenals and human urine shows that mammals like non-vertebrates and toads may synthesize cardiac glycosides in their adrenals and possibly in hypothalamus. The hypothalamus also forms other compounds of unknown structure which bind to the cardiac glycoside receptor site. The differential functions of endogenously formed ouabain and of a digoxin-like substance are unclear. The detailed knowledge of the physiological role of both endogenously formed cardiac glycosides in the regulation of blood pressure has still to be worked out.

  9. Flavor structure of the nucleon electromagnetic form factors and transverse charge densities in the chiral quark-soliton model

    NASA Astrophysics Data System (ADS)

    Silva, António; Urbano, Diana; Kim, Hyun-Chul

    2018-02-01

    We investigate the flavor decomposition of the electromagnetic form factors of the nucleon, based on the chiral quark-soliton model (χQSM) with symmetry-conserving quantization. We consider the rotational 1/N_c and linear strange-quark mass (ms) corrections. We discuss the results of the flavor-decomposed electromagnetic form factors in comparison with the recent experimental data. In order to see the effects of the strange quark, we compare the SU(3) results with those of SU(2). Finally, we discuss the transverse charge densities for both unpolarized and polarized nucleons. The transverse charge density inside a neutron turns out to be negative in the vicinity of the center within the SU(3) χQSM, which can be explained by the contribution of the strange quark.

  10. Fully relativistic form factor for Thomson scattering.

    PubMed

    Palastro, J P; Ross, J S; Pollock, B; Divol, L; Froula, D H; Glenzer, S H

    2010-03-01

    We derive a fully relativistic form factor for Thomson scattering in unmagnetized plasmas valid to all orders in the normalized electron velocity, beta[over ]=v[over ]/c. The form factor is compared to a previously derived expression where the lowest order electron velocity, beta[over], corrections are included [J. Sheffield, (Academic Press, New York, 1975)]. The beta[over ] expansion approach is sufficient for electrostatic waves with small phase velocities such as ion-acoustic waves, but for electron-plasma waves the phase velocities can be near luminal. At high phase velocities, the electron motion acquires relativistic corrections including effective electron mass, relative motion of the electrons and electromagnetic wave, and polarization rotation. These relativistic corrections alter the scattered emission of thermal plasma waves, which manifest as changes in both the peak power and width of the observed Thomson-scattered spectra.

  11. Acceptability of Family Violence: Underlying Ties Between Intimate Partner Violence and Child Abuse.

    PubMed

    Gracia, Enrique; Rodriguez, Christina M; Martín-Fernández, Manuel; Lila, Marisol

    2017-05-01

    Intimate partner violence (IPV) and child abuse (CA) are two forms of family violence with shared qualities and risk factors, and are forms of violence that tend to overlap. Acceptability of violence in partner relationships is a known risk factor in IPV just as acceptability of parent-child aggression is a risk factor in CA. We hypothesized that these acceptability attitudes may be linked and represent the expression of a general, underlying nonspecific acceptance of violence in close family relationships. The sample involved 164 male IPV offenders participating in a batterer intervention program. Implicit measures, which assess constructs covertly to minimize response distortions, were administered to assess acceptability of partner violence against women and acceptability of parent-child aggression. To determine whether acceptability attitudes regarding both forms of violence were related to a higher order construct tapping general acceptance of family violence, Bayesian confirmatory factor analyses were conducted. Findings supported a hierarchical (bifactor) model with a general factor expressing a nonspecific acceptance of family violence, and two specific factors reflecting acceptability of violence in intimate partner and parent-child relationships, respectively. This hierarchical model supporting a general acceptance of violence in close family relationships can inform future research aiming to better understand the connections between IPV and CA.

  12. A formal anthropological view of motivation models of problematic MMO play: achievement, social, and immersion factors in the context of culture.

    PubMed

    Snodgrass, Jeffrey G; Dengah, H J Francois; Lacy, Michael G; Fagan, Jesse

    2013-04-01

    Yee (2006) found three motivational factors-achievement, social, and immersion-underlying play in massively multiplayer online role-playing games ("MMORPGs" or "MMOs" for short). Subsequent work has suggested that these factors foster problematic or addictive forms of play in online worlds. In the current study, we used an online survey of respondents (N = 252), constructed and also interpreted in reference to ethnography and interviews, to examine problematic play in the World of Warcraft (WoW; Blizzard Entertainment, 2004-2013). We relied on tools from psychological anthropology to reconceptualize each of Yee's three motivational factors in order to test for the possible role of culture in problematic MMO play: (a) For achievement, we examined how "cultural consonance" with normative understandings of success might structure problematic forms of play; (b) for social, we analyzed the possibility that developing overvalued virtual relationships that are cutoff from offline social interactions might further exacerbate problematic play; and (c) in relation to immersion, we examined how "dissociative" blurring of actual- and virtual-world identities and experiences might contribute to problematic patterns. Our results confirmed that compared to Yee's original motivational factors, these culturally sensitive measures better predict problematic forms of play, pointing to the important role of sociocultural factors in structuring online play.

  13. A survey of scientific literacy to provide a foundation for designing science communication in Japan.

    PubMed

    Kawamoto, Shishin; Nakayama, Minoru; Saijo, Miki

    2013-08-01

    There are various definitions and survey methods for scientific literacy. Taking into consideration the contemporary significance of scientific literacy, we have defined it with an emphasis on its social aspects. To acquire the insights needed to design a form of science communication that will enhance the scientific literacy of each individual, we conducted a large-scale random survey within Japan of individuals older than 18 years, using a printed questionnaire. The data thus acquired were analyzed using factor analysis and cluster analysis to create a 3-factor/4-cluster model of people's interest and attitude toward science, technology and society and their resulting tendencies. Differences were found among the four clusters in terms of the three factors: scientific factor, social factor, and science-appreciating factor. We propose a plan for designing a form of science communication that is appropriate to this current status of scientific literacy in Japan.

  14. Selective concentration of aromatic bases from water with a resin adsorbent

    USGS Publications Warehouse

    Stuber, H.A.; Leenheer, J.A.

    1983-01-01

    Aromatic bases are concentrated from water on columns of a resin adsorbent and recovered by aqueous-acid elution. The degree of concentration attainable depends on the ratio of the capacity factor (k) of the neutral form of the amine to that of the ionized form. Capacity factors of ionic forms of amines on XAD-8 resin (a methylacrylic ester polymer) are greater than zero, ranging from 20 to 250 times lower than those of their neutral forms; they increase with increasing hydrophobicity of the amine. Thus, desorption by acid is an edition (k during desorption >0) rather than a displacement (k during desorption = 0) process. The degree of concentration attainable on XAD-8 resin varies with the hydrophobicity of the amine, being limited for hydrophilic solutes (for example, pyridine) by small neutral-form k's, reaching a maximum for amines of intermediate hydrophobicity (for example, quinoline), and decreasing for more hydrophobc solutes (for example, acridine) because of their large ionic-form k's.

  15. Induced drag ideal efficiency factor of arbitrary lateral-vertical wing forms

    NASA Technical Reports Server (NTRS)

    Deyoung, J.

    1980-01-01

    A relatively simple equation is presented for estimating the induced drag ideal efficiency factor e for arbitrary cross sectional wing forms. This equation is based on eight basic but varied wing configurations which have exact solutions. The e function which relates the basic wings is developed statistically and is a continuous function of configuration geometry. The basic wing configurations include boxwings shaped as a rectangle, ellipse, and diamond; the V-wing; end-plate wing; 90 degree cruciform; circle dumbbell; and biplane. Example applications of the e equations are made to many wing forms such as wings with struts which form partial span rectangle dumbbell wings; bowtie, cruciform, winglet, and fan wings; and multiwings. Derivations are presented in the appendices of exact closed form solutions found of e for the V-wing and 90 degree cruciform wing and for an asymptotic solution for multiwings.

  16. Method for forming an in situ oil shale retort with horizontal free faces

    DOEpatents

    Ricketts, Thomas E.; Fernandes, Robert J.

    1983-01-01

    A method for forming a fragmented permeable mass of formation particles in an in situ oil shale retort is provided. A horizontally extending void is excavated in unfragmented formation containing oil shale and a zone of unfragmented formation is left adjacent the void. An array of explosive charges is formed in the zone of unfragmented formation. The array of explosive charges comprises rows of central explosive charges surrounded by a band of outer explosive charges which are adjacent side boundaries of the retort being formed. The powder factor of each outer explosive charge is made about equal to the powder factor of each central explosive charge. The explosive charges are detonated for explosively expanding the zone of unfragmented formation toward the void for forming the fragmented permeable mass of formation particles having a reasonably uniformly distributed void fraction in the in situ oil shale retort.

  17. Electromagnetic properties of baryon resonances

    NASA Astrophysics Data System (ADS)

    Tiator, Lothar

    2013-10-01

    Longitudinal and transverse transition form factors for most of the four-star nucleon resonances have been obtained from high-quality cross section data and polarization observables measured at MAMI, ELSA, BATES, GRAAL and CEBAF. As an application, we further show how the transition form factors can be used to obtain empirical transverse charge densities. Contour plots of the thus derived densities are shown and compared for the Roper and S11 nucleon resonances.

  18. Left Handed Materials Based on Magnetic Nanocomposites

    DTIC Science & Technology

    2006-10-18

    theory that unifies DNMs and SNMs as a function of two flmdamental material parameters: quality factors for permittivity (Qe=e’/e") and permeability (Qu...simultaneously negative effective permeability/uff and permittivity Seff to form LHM or only single negative parameter (SNM) to form negative indexed...developed a theory that unifies DNMs and SNMs as a function of two fundamental material parameters: quality factors for permittivity (Q, = -’/ 6") and

  19. Towards a dispersive determination of the η and η' transition form factors

    NASA Astrophysics Data System (ADS)

    Kubis, Bastian

    2018-01-01

    We discuss status and prospects of a dispersive analysis of the η and η' transition form factors. Particular focus is put on the various pieces of experimental information that serve as input to such a calculation. These can help improve on the precision of an evaluation of the η and η' pole contributions to hadronic light-by-light scattering in the anomalous magnetic moment of the muon.

  20. The Psychometric Properties and Factor Structure of a Welsh Translation of the School Short Form of the Coopersmith Self-Esteem Inventory

    ERIC Educational Resources Information Center

    Hills, Peter R.; Francis, Leslie J.; Thomas, Enlli

    2007-01-01

    The psychometric properties and factor structure of a Welsh translation of the school short form of the Coopersmith Self-esteem Inventory (SEI-SSF), which is widely used as a measure of children's global self-esteem, was investigated among a sample of 681 pupils attending Welsh-medium primary schools in Wales. It has generally been assumed that…

  1. The Role of the Five Factor Model of Personality in the Perceptions of Negative and Positive Forms of Work-Nonwork Spillover: A Meta-Analytic Review

    ERIC Educational Resources Information Center

    Michel, Jesse S.; Clark, Malissa A.; Jaramillo, David

    2011-01-01

    The present meta-analysis examines the relationships between the Five Factor Model (FFM) of personality and negative and positive forms of work-nonwork spillover (e.g., work-family conflict and facilitation). Results, based on aggregated correlations drawn from 66 studies and 72 independent samples (Total N = 28,127), reveal that the FFM is…

  2. Meson properties and phase diagrams in a SU(3) nonlocal PNJL model with lattice-QCD-inspired form factors

    NASA Astrophysics Data System (ADS)

    Carlomagno, J. P.

    2018-05-01

    We study the features of a nonlocal SU(3) Polyakov-Nambu-Jona-Lasinio model that includes wave-function renormalization. Model parameters are determined from vacuum phenomenology considering lattice-QCD-inspired nonlocal form factors. Within this framework, we analyze the properties of light scalar and pseudoscalar mesons at finite temperature and chemical potential determining characteristics of deconfinement and chiral restoration transitions.

  3. Male Role Norms Inventory--Short Form (MRNI-SF): Development, Confirmatory Factor Analytic Investigation of Structure, and Measurement Invariance across Gender

    ERIC Educational Resources Information Center

    Levant, Ronald F.; Hall, Rosalie J.; Rankin, Thomas J.

    2013-01-01

    The current study reports the development from the Male Role Norms Inventory-Revised (MRNI-R; Levant, Rankin, Williams, Hasan, & Smalley, 2010) of the 21-item MRNI-Short Form (MRNI-SF). Confirmatory factor analysis of MRNI-SF responses from a sample of 1,017 undergraduate participants (549 men, 468 women) indicated that the best fitting "bifactor"…

  4. Factor Structure of the Devereux Early Childhood Assessment Clinical Form in Low-Income Hispanic American Bilingual Preschool Children

    ERIC Educational Resources Information Center

    Oades-Sese, Geraldine V.; Kaliski, Pamela K.; Weiss, Karen

    2010-01-01

    The Devereux Early Childhood Assessment Clinical Form (DECA-C) is the first instrument to measure the social-emotional resilience of young children from ages 2 to 5 years. This study is an important step toward gathering validity evidence for the teacher-rated DECA-C. This is the first study to investigate the DECA-C factor structure and the first…

  5. Mathematical Models of the Circadian Sleep-Wake Cycle.

    DTIC Science & Technology

    1984-05-01

    circadian geber , 97,98 system precision, 4 Form factor Damped oscillators, mutual excitation of, and relationship to ratio of deviations, 37 self-sustainment...rhythms, 5-6 Forced internal desynebronization, by Zeit- incorporation of, into models of circadian geber , 97,98 system precision, 4 Form factor Damped...equation, for modeling of circadian geber phase, and modification by fre- rhythms, 19 quency coefficient, 54,55,56 Oscillatory range, effects of

  6. Λ b→pl⁻ν¯ l form factors from lattice QCD with static b quarks

    DOE PAGES

    Detmold, William; Lin, C.-J. David; Meinel, Stefan; ...

    2013-07-23

    We present a lattice QCD calculation of form factors for the decay Λ b→pμ⁻ν¯ μ, which is a promising channel for determining the Cabibbo-Kobayashi-Maskawa matrix element |V ub| at the Large Hadron Collider. In this initial study we work in the limit of static b quarks, where the number of independent form factors reduces to two. We use dynamical domain-wall fermions for the light quarks, and perform the calculation at two different lattice spacings and at multiple values of the light-quark masses in a single large volume. Using our form factor results, we calculate the Λ b→pμ⁻ν¯ μ differential decaymore » rate in the range 14 GeV²≤q²≤q² max, and obtain the integral ∫ q²max 14 GeV²[dΓ/dq²]dq²/|V ub|²=15.3±4.2 ps⁻¹. Combined with future experimental data, this will give a novel determination of |V ub| with about 15% theoretical uncertainty. The uncertainty is dominated by the use of the static approximation for the b quark, and can be reduced further by performing the lattice calculation with a more sophisticated heavy-quark action.« less

  7. D → π and D → K semileptonic form factors with Nf = 2 + 1 + 1 twisted mass fermions

    NASA Astrophysics Data System (ADS)

    Lubicz, Vittorio; Riggio, Lorenzo; Salerno, Giorgio; Simula, Silvano; Tarantino, Cecilia

    2018-03-01

    We present a lattice determination of the vector and scalar form factors of the D → π(K)lv semileptonic decays, which are relevant for the extraction of the CKM matrix elements |Vcd| and |Vcs| from experimental data. Our analysis is based on the gauge configurations produced by the European Twisted Mass Collaboration with Nf = 2 + 1 +1 flavors of dynamical quarks. We simulated at three different values of the lattice spacing and with pion masses as small as 210 MeV. The matrix elements of both vector and scalar currents are determined for a plenty of kinematical conditions in which parent and child mesons are either moving or at rest. Lorentz symmetry breaking due to hypercubic effects is clearly observed in the data and included in the decomposition of the current matrix elements in terms of additional form factors. After the extrapolations to the physical pion mass and to the continuum limit the vector and scalar form factors are determined in the whole kinematical region from q2 = 0 up to qmax2 = (MD - Mπ(K))2 accessible in the experiments, obtaining a good overall agreement with experiments, except in the region at high values of q2 where some deviations are visible.

  8. Intrinsic and Extrinsic Modifiers of the Regulative Capacity of the Developing Liver

    PubMed Central

    Shin, Donghun; Weidinger, Gilbert; Moon, Randall T.; Stainier, Didier Y.R.

    2012-01-01

    Zebrafish wnt2bb mutants initially fail to form a liver, but surprisingly the liver eventually forms in a majority of these embryos which then develop into fertile adults. This unexpected result raised the possibility that identifying the mechanisms of liver formation in wnt2bb mutants could provide insights into the poorly understood yet general principle of regulative development, a process by which some cells can change fate in order to compensate for a deficiency. Here, we identify two factors that underlie the regulative capacity of endodermal tissues: an intrinsic factor, Sox32, a transcription factor of the SoxF subfamily, and an extrinsic factor, Fgf10a. sox32 is expressed in the extrahepatic duct primordium which is not affected in wnt2bb mutants. Blocking Sox32 function prevented liver formation in most wnt2bb mutants. fgf10a, which is expressed in the mesenchyme surrounding non-hepatic endodermal cells, negatively impacts the regulative capacity of endodermal tissues. In Wnt/β-catenin signaling deficient embryos, in which the liver completely fails to form, the repression of Fgf10a function allowed liver formation. Altogether, these studies reveal that there is more than one way to form a liver, and provide molecular insights into the phenomenon of tissue plasticity. PMID:22313811

  9. Accurate optimization of amino acid form factors for computing small-angle X-ray scattering intensity of atomistic protein structures

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tong, Dudu; Yang, Sichun; Lu, Lanyuan

    2016-06-20

    Structure modellingviasmall-angle X-ray scattering (SAXS) data generally requires intensive computations of scattering intensity from any given biomolecular structure, where the accurate evaluation of SAXS profiles using coarse-grained (CG) methods is vital to improve computational efficiency. To date, most CG SAXS computing methods have been based on a single-bead-per-residue approximation but have neglected structural correlations between amino acids. To improve the accuracy of scattering calculations, accurate CG form factors of amino acids are now derived using a rigorous optimization strategy, termed electron-density matching (EDM), to best fit electron-density distributions of protein structures. This EDM method is compared with and tested againstmore » other CG SAXS computing methods, and the resulting CG SAXS profiles from EDM agree better with all-atom theoretical SAXS data. By including the protein hydration shell represented by explicit CG water molecules and the correction of protein excluded volume, the developed CG form factors also reproduce the selected experimental SAXS profiles with very small deviations. Taken together, these EDM-derived CG form factors present an accurate and efficient computational approach for SAXS computing, especially when higher molecular details (represented by theqrange of the SAXS data) become necessary for effective structure modelling.« less

  10. Deducing the form factors for shear used in the calculus of the displacements based on strain energy methods. Mathematical approach for currently used shapes

    NASA Astrophysics Data System (ADS)

    Constantinescu, E.; Oanta, E.; Panait, C.

    2017-08-01

    The paper presents an initial study concerning the form factors for shear, for a rectangular and for a circular cross section, being used an analytical method and a numerical study. The numerical study considers a division of the cross section in small areas and uses the power of the definitions in order to compute the according integrals. The accurate values of the form factors are increasing the accuracy of the displacements computed by the use of the strain energy methods. The knowledge resulted from this study will be used for several directions of development: calculus of the form factors for a ring-type cross section of variable ratio of the inner and outer diameters, calculus of the geometrical characteristics of an inclined circular segment and, using a Bool algebra that operates with geometrical shapes, for an inclined circular ring segment. These shapes may be used to analytically define the geometrical model of a complex composite section, i.e. a ship hull cross section. The according calculus relations are also useful for the development of customized design commands in CAD commercial applications. The paper is a result of the long run development of original computer based instruments in engineering of the authors.

  11. Development of a short form of the Japanese version of the Interpersonal Relationship Inventory.

    PubMed

    Sumi, Katsunori

    2009-10-01

    The Interpersonal Relationship Inventory (Tilden, Nelson, & May, 1990a) is a 39-item self-report measure to assess three aspects (support, reciprocity, and conflict) of perceived social relationships. In this research, short forms of the Japanese version (Sumi, 2003) of the inventory were developed on the basis of data from two sources. For the item selection, data from 340 Japanese college students (148 women, 192 men; M age = 21.6 yr., SD = 1.6) who completed the original full form of the inventory were used to create three internally consistent short forms. The reliability and construct validity of the short forms were examined upon administering them to among 513 college students (226 women, 287 men; M age =19.9 yr., SD = 1.4). All the subscales of the short forms had acceptable internal consistency (alphas = .70-.90) and test-retest reliability (rs = .72-.81). Confirmatory factor analysis of each short form supported the fact that each form had a three-factor structure. Scores on the subscales shared acceptable overlapping variance with the corresponding subscale scores of the original full form, and these scores were weakly but significantly correlated with the scores for satisfaction with social support, loneliness, and perceived stress. All the short forms had acceptable reliability and construct validity.

  12. Psychometric testing of the properties of the spiritual health scale short form.

    PubMed

    Hsiao, Ya-Chu; Chiang, Yi-Chien; Lee, Hsiang-Chun; Han, Chin-Yen

    2013-11-01

    To further examine the psychometric properties of the spiritual health scale short form, including its reliability and validity. Spirituality is one of the main factors associated with good health outcomes. A reliable and valid instrument to measure spirituality is essential to identify the spiritual needs of an individual and to evaluate the effect of spiritual care. A cross-sectional study design was used. The study was conducted in six nursing schools in northern, central and southern Taiwan. The inclusion criterion for participants was nursing students with clinical practice experience. Initially, 1141 participants were recruited for the study, but 67 were absent and 48 did not complete the questionnaires. A total of 1026 participants were finally recruited, indicating a response rate of 89·9%. The psychometric testing of the spiritual health scale short form included construct validity with confirmatory factor analysis, known-group validity and internal consistency reliability. The results of the confirmatory factor analysis supported the five-factor model as an acceptable model fit. In the known-group validity, the results indicated that people who are in the category of primary religious affiliation have better spiritual health than people in the category of secondary religious affiliation and atheism. The result also indicated that the 24-item spiritual health scale short form achieved an acceptable internal consistency coefficient. The findings suggest that the spiritual health scale short form is a valid and reliable instrument for the appraisal of individual spiritual health. The spiritual health scale short form could provide useful information to guide clinical practice in assessing and managing people's spiritual health in Taiwan. © 2013 John Wiley & Sons Ltd.

  13. Expression, purification and preliminary X-ray diffraction studies of the transcriptional factor PyrR from Bacillus halodurans

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Arreola, Rodrigo; Vega-Miranda, Anita; Gómez-Puyou, Armando

    The gene-regulation factor PyrR from B. halodurans has been crystallized in two crystal forms. Preliminary crystallographic analysis showed that the protein forms tetramers in both space groups. The PyrR transcriptional regulator is widely distributed in bacteria. This RNA-binding protein is involved in the control of genes involved in pyrimidine biosynthesis, in which uridyl and guanyl nucleotides function as effectors. Here, the crystallization and preliminary X-ray diffraction analysis of two crystal forms of Bacillus halodurans PyrR are reported. One of the forms belongs to the monoclinic space group P2{sub 1} with unit-cell parameters a = 59.7, b = 87.4, c =more » 72.1 Å, β = 104.4°, while the other form belongs to the orthorhombic space group P22{sub 1}2{sub 1} with unit-cell parameters a = 72.7, b = 95.9, c = 177.1 Å. Preliminary X-ray diffraction data analysis and molecular-replacement solution revealed the presence of four and six monomers per asymmetric unit; a crystallographic tetramer is formed in both forms.« less

  14. Effects of pharmaceutical processing on pepsin activity during the formulation of solid dosage forms.

    PubMed

    Kristó, Katalin; Pintye-Hódi, Klára

    2013-02-01

    The main aim of this study was to investigate the effects of pharmaceutical technological methods on pepsin activity during the formulation of solid dosage forms. The circumstances of direct compression and wet granulation were modeled. During direct compression, the heat and the compression force must be taken into consideration. The effects of these parameters were investigated in three materials (pure pepsin, and 1:1 (w/w) pepsin-tartaric acid and 1:1 (w/w) pepsin-citric acid powder mixtures). It was concluded that direct compression is appropriate for the formulation of solid dosage forms containing pepsin through application without acids or with acids at low compression force. The effects of wet granulation were investigated with a factorial design for the same three materials. The factors were time, temperature and moisture content. There was no significant effect of the factors when acids were not applied. Temperature was a significant factor when acids were applied. The negative effect was significantly higher for citric acid than for tartaric acid. It was found that wet granulation can be utilized for the processing of pepsin into solid dosage forms under well-controlled circumstances. The application of citric acid is not recommended during the formulation of solid dosage forms through wet granulation. A mathematically based optimization may be necessary for preformulation studies of the preparation of dosage forms containing sensitive enzymes.

  15. The place character as land use change determinant in Deli Serdang

    NASA Astrophysics Data System (ADS)

    Lindarto, D.; Sirojuzilam; Badaruddin; Aulia, DN

    2018-03-01

    The Mebidangro concept of development (Medan, Binjai, Deli Serdang, Karo) in Sumatera Utara creating peri urban area in region hinterland Medan city especially in Tembung village, Percut Sei Tuan District. This peri urban area is a conjunction of several rural-urban activities that forming a friendly atmosphere. The dynamic of population structure shows occurrence the sprawl of land use change condition. In the site of the urban region showing the unique performance that built the place character. The aim of the study is to uncover the place character as one of land use change determinant factors. The study conducted with quantitative approach intended at obtaining variables which describing several factors forming land use change. Descriptive approach give an idea, justification, and fact-finding with correct interpretation. Data collected through a purposive sampling of 320 respondents who stay and built the building and land between 2010 till 2014. With overlay figure/ground technique, scoring analysis, descriptive quantitative and SEM (Structural Equational Models) gained a result that urban heritage (p=0,008) potentially as one of the main land use change driving factors besides accessibility (p=0,039), infrastructure (p=0,010), social-economic (p=0,038) in fact topographic factor (p=0,663) was inversely potentially. The implication of the findings is required intensive attention toward the form of place character (mosque, the quarter, district activity, peri urban edges city and railway) as determinant factors of land use change considering forming the identity of the rapid change in land use transformation.

  16. The spontaneous emission factor for lasers with gain induced waveguiding

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Newstein, M.

    1984-11-01

    The expression for the spontaneous emission factor for lasers with gain induced waveguiding has a factor K, called by Petermann ''the astigmatism parameter.'' This factor has been invoked to explain spectral and dynamic characteristics of this class of lasers. We contend that the widely accepted form of the K factor is based on a derivation which is not appropriate for the typical laser situation where the spontaneous emission factor is much smaller than unity. An alternative derivation is presented which leads to a different form for the K factor. The new expression predicts much smaller values under conditions where themore » previous theory gave values large compared to unity. Petermann's form for the K factor is shown to be relevant to large gain linear amplifiers where the power is amplified spontaneous emission noise. The expression for the power output has Petermann's value of K as a factor. The difference in the two situations is that in the laser oscillator the typical atom of interest couples a small portion of its incoherent spontaneous emission into the dominant mode, whereas in the amplifier only the atoms at the input end are important as sources and their output is converted to a greater degree into the dominant mode through the propagation process. In this analysis the authors use a classical model of radiating point dipoles in a continuous medium characterized by a complex permittivity. Since uncritical use of this model will lead to infinite radiation resistance they address the problem of its self-consistency.« less

  17. Evaluation of the U.S. Army’s Aids Education Program

    DTIC Science & Technology

    1992-03-25

    34 scaiac (contlinad) Initial Factor Notd : N. Preatation flatbed : Varimax Notation NedjiM Prai Factor Pattern Notated Factor Pattern Factor StrUCture...material, the graphics contained in this appendix may be reproduced in the form of slides, or enlarged, laminated and bound together for use as a flip

  18. Forms of Address in Chilean Spanish

    ERIC Educational Resources Information Center

    Bishop, Kelley; Michnowicz, Jim

    2010-01-01

    The present investigation examines possible social and linguistic factors that influence forms of address used in Chilean Spanish with various interlocutors. A characteristic of the Spanish of Chile is the use of a variety of forms of address for the second person singular, "tu", "vos", and "usted", with corresponding…

  19. Career Adapt-Abilities Scale--Italian Form: Psychometric Properties and Relationships to Breadth of Interests, Quality of Life, and Perceived Barriers

    ERIC Educational Resources Information Center

    Soresi, Salvatore; Nota, Laura; Ferrari, Lea

    2012-01-01

    The Career Adapt-Abilities Scale (CAAS)-Italian Form consists of four 6-item scales, which measure concern, control, curiosity, and confidence as psychosocial resources for managing occupational transitions, developmental tasks, and work traumas. The 24-item CAAS-Italian Form is identical to the International Form 2.0. The factor structure was…

  20. Microstructural analysis of hot press formed 22MnB5 steel

    NASA Astrophysics Data System (ADS)

    Aziz, Nuraini; Aqida, Syarifah Nur; Ismail, Izwan

    2017-10-01

    This paper presents a microstructural study on hot press formed 22MnB5 steel for enhanced mechanical properties. Hot press forming process consists of simultaneous forming and quenching of heated blank. The 22MnB5 steel was processed at three different parameter settings: quenching time, water temperature and water flow rate. 22MnB5 was processed using 33 full factorial design of experiment (DOE). The full factorial DOE was designed using three factors of quenching time, water temperature and water flow rate at three levels. The factors level were quenching time range of 5 - 11 s, water temperature; 5 - 27°C and water flow rate; 20 - 40 L/min. The as-received and hot press forming processed steel was characterised for metallographic study and martensitic structure area percentage using JEOL Field Emission Scanning Electron Microscopic (FESEM). From the experimental finding, the hot press formed 22MnB5 steel consisted of 50 to 84% martensitic structure area. The minimum quenching time of 8 seconds was required to obtain formed sample with high percentage of martensite. These findings contribute to initial design of processing parameters in hot press forming of 22MnB5 steel blanks for automotive component.

  1. Connecting different TMD factorization formalisms in QCD

    DOE PAGES

    Collins, John; Rogers, Ted C.

    2017-09-11

    In the original Collins-Soper-Sterman (CSS) presentation of the results of transverse-momentum-dependent (TMD) factorization for the Drell-Yan process, results for perturbative coefficients can be obtained from calculations for collinear factorization. Here we show how to use these results, plus known results for the quark form factor, to obtain coefficients for TMD factorization in more recent formulations, e.g., that due to Collins, and apply them to known results at ordermore » $$\\alpha_s^2$$ and $$\\alpha_s^3$$. We also show that the ``non-perturbative'' functions as obtained from fits to data are equal in the two schemes. We compile the higher-order perturbative inputs needed for the updated CSS scheme by appealing to results obtained in a variety of different formalisms. In addition, we derive the connection between both versions of the CSS formalism and several formalisms based in soft-collinear effective theory (SCET). As a result, our work uses some important new results for factorization for the quark form factor, which we derive.« less

  2. Connecting different TMD factorization formalisms in QCD

    NASA Astrophysics Data System (ADS)

    Collins, John; Rogers, Ted C.

    2017-09-01

    In the original Collins-Soper-Sterman (CSS) presentation of the results of transverse-momentum-dependent (TMD) factorization for the Drell-Yan process, results for perturbative coefficients can be obtained from calculations for collinear factorization. Here we show how to use these results, plus known results for the quark form factor, to obtain coefficients for TMD factorization in more recent formulations, e.g., that due to Collins, and apply them to known results at order αs2 and αs3. We also show that the "nonperturbative" functions as obtained from fits to data are equal in the two schemes. We compile the higher-order perturbative inputs needed for the updated CSS scheme by appealing to results obtained in a variety of different formalisms. In addition, we derive the connection between both versions of the CSS formalism and several formalisms based in soft-collinear effective theory (SCET). Our work uses some important new results for factorization for the quark form factor, which we derive.

  3. Connecting different TMD factorization formalisms in QCD

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Collins, John; Rogers, Ted C.

    In the original Collins-Soper-Sterman (CSS) presentation of the results of transverse-momentum-dependent (TMD) factorization for the Drell-Yan process, results for perturbative coefficients can be obtained from calculations for collinear factorization. Here we show how to use these results, plus known results for the quark form factor, to obtain coefficients for TMD factorization in more recent formulations, e.g., that due to Collins, and apply them to known results at ordermore » $$\\alpha_s^2$$ and $$\\alpha_s^3$$. We also show that the ``non-perturbative'' functions as obtained from fits to data are equal in the two schemes. We compile the higher-order perturbative inputs needed for the updated CSS scheme by appealing to results obtained in a variety of different formalisms. In addition, we derive the connection between both versions of the CSS formalism and several formalisms based in soft-collinear effective theory (SCET). As a result, our work uses some important new results for factorization for the quark form factor, which we derive.« less

  4. Spin-1 Particles and Perturbative QCD

    NASA Astrophysics Data System (ADS)

    de Melo, J. P. B. C.; Frederico, T.; Ji, Chueng-Ryong

    2018-07-01

    Due to the angular condition in the light-front dynamics (LFD), the extraction of the electromagnetic form factors for spin-1 particles can be uniquely determined taking into account implicitly non-valence and/or the zero-mode contributions to the matrix elements of the electromagnetic current. No matter which matrix elements of the electromagnetic current is used to extract the electromagnetic form factors, the same unique result is obtained. As physical observables, the electromagnetic form factors obtained from matrix elements of the current in LFD must be equal to those obtained in the instant form calculations. Recently, the Babar collaboration (Phys Rev D 78:071103, 2008) has analyzed the reaction e^+ + e^-→ ρ ^+ + ρ ^- at √{s}=10.58 GeV to measure the cross section as well as the ratios of the helicity amplitudes F_{λ 'λ }. We present our recent analysis of the Babar data for the rho meson considering the angular condition in LFD to put a stringent test on the onset of asymptotic perturbative QCD and predict the energy regime where the subleading contributions are still considerable.

  5. The Built Environment and Active Travel: Evidence from Nanjing, China.

    PubMed

    Feng, Jianxi

    2016-03-08

    An established relationship exists between the built environment and active travel. Nevertheless, the literature examining the impacts of different components of the built environment is limited. In addition, most existing studies are based on data from cities in the U.S. and Western Europe. The situation in Chinese cities remains largely unknown. Based on data from Nanjing, China, this study explicitly examines the influences of two components of the built environment--the neighborhood form and street form--on residents' active travel. Binary logistic regression analyses examined the effects of the neighborhood form and street form on subsistence, maintenance and discretionary travel, respectively. For each travel purpose, three models are explored: a model with only socio-demographics, a model with variables of the neighborhood form and a complete model with all variables. The model fit indicator, Nagelkerke's ρ², increased by 0.024 when neighborhood form variables are included and increased by 0.070 when street form variables are taken into account. A similar situation can be found in the models of maintenance activities and discretionary activities. Regarding specific variables, very limited significant impacts of the neighborhood form variables are observed, while almost all of the characteristics of the street form show significant influences on active transport. In Nanjing, street form factors have a more profound influence on active travel than neighborhood form factors. The focal point of the land use regulations and policy of local governments should shift from the neighborhood form to the street form to maximize the effects of policy interventions.

  6. Associations between Macrophyte Life Forms and Environmental and Morphometric Factors in a Large Sub-tropical Floodplain

    PubMed Central

    Schneider, Berenice; Cunha, Eduardo R.; Marchese, Mercedes; Thomaz, Sidinei M.

    2018-01-01

    Macrophyte assemblages are composed of species with different life forms and various ecological functions. Our aim was to investigate the potential environmental determinants of changes in the biomass of individual life forms and of the composition of the macrophyte assemblage in terms of life forms diversity. We sampled 23 waterbodies at low and high water levels in the Middle Paraná River floodplain. Macrophyte biomass samples were collected and classified in terms of life forms. We performed a redundancy analysis using the biomass of the various life forms to assess the importance of environmental variables to the composition of macrophyte life forms. Linear regressions were applied to investigate the environmental determinants of the biomasses of individual life forms. The degree of connectivity and the combination of depth, hydrology and nitrate were the main determinants of the composition in terms of life forms. The biomass of each individual life form was explained by different combinations of environmental variables, but the connectivity was the most important one. Our study shows that groups of species with similar life forms respond to environmental factors in particular ways, which might alter the biomass composition of life forms. Given that the ecosystem functioning depends on the functional characteristics of local communities, our findings about the relation between environmental changes and the community composition in terms of life forms (or functional composition) can be a helpful tool for predicting changes on ecosystem processes (such as nutrient cycling) against possible future scenarios. PMID:29515608

  7. Measurement of the γγ*→η and γγ*→η' transition form factors

    DOE PAGES

    del Amo Sanchez, P.; Lees, J. P.; Poireau, V.; ...

    2011-09-06

    We study the reactions e⁺e⁻→e⁺e⁻η (') in the single-tag mode and measure the γγ*→η (') transition form factors in the momentum-transfer range from 4 to 40 GeV². The analysis is based on 469 fb⁻¹ of integrated luminosity collected at PEP-II with the BABAR detector at e⁺e⁻ center-of-mass energies near 10.6 GeV.

  8. calculation of B → D*lv form factor at zero recoil using the Oktay-Kronfeld action

    NASA Astrophysics Data System (ADS)

    Bailey, Jon A.; Bhattacharya, Tanmoy; Gupta, Rajan; Jang, Yong-Chull; Lee, Weonjong; Leem, Jaehoon; Park, Sungwoo; Yoon, Boram

    2018-03-01

    We present the first preliminary results for the semileptonic form factor hA1 (w = 1)/ρAj at zero recoil for the B → D*lv decay using lattice QCD with four flavors of sea quarks. We use the HISQ staggered action for the light valence and sea quarks (the MILC HISQ configurations), and the Oktay-Kronfeld (OK) action for the heavy valence quarks.

  9. Measurement of the γγ*→η and γγ*→η' transition form factors

    NASA Astrophysics Data System (ADS)

    Del Amo Sanchez, P.; Lees, J. P.; Poireau, V.; Prencipe, E.; Tisserand, V.; Garra Tico, J.; Grauges, E.; Martinelli, M.; Milanes, D. A.; Palano, A.; Pappagallo, M.; Eigen, G.; Stugu, B.; Sun, L.; Brown, D. N.; Kerth, L. T.; Kolomensky, Yu. G.; Lynch, G.; Osipenkov, I. L.; Koch, H.; Schroeder, T.; Asgeirsson, D. J.; Hearty, C.; Mattison, T. S.; McKenna, J. A.; Khan, A.; Blinov, V. E.; Botov, A. A.; Buzykaev, A. R.; Druzhinin, V. P.; Golubev, V. B.; Kravchenko, E. A.; Onuchin, A. P.; Serednyakov, S. I.; Skovpen, Yu. I.; Solodov, E. P.; Todyshev, K. Yu.; Yushkov, A. N.; Bondioli, M.; Curry, S.; Kirkby, D.; Lankford, A. J.; Mandelkern, M.; Martin, E. C.; Stoker, D. P.; Atmacan, H.; Gary, J. W.; Liu, F.; Long, O.; Vitug, G. M.; Campagnari, C.; Hong, T. M.; Kovalskyi, D.; Richman, J. D.; West, C. A.; Eisner, A. M.; Heusch, C. A.; Kroseberg, J.; Lockman, W. S.; Martinez, A. J.; Schalk, T.; Schumm, B. A.; Seiden, A.; Winstrom, L. O.; Cheng, C. H.; Doll, D. A.; Echenard, B.; Hitlin, D. G.; Ongmongkolkul, P.; Porter, F. C.; Rakitin, A. Y.; Andreassen, R.; Dubrovin, M. S.; Meadows, B. T.; Sokoloff, M. D.; Bloom, P. C.; Ford, W. T.; Gaz, A.; Nagel, M.; Nauenberg, U.; Smith, J. G.; Wagner, S. R.; Ayad, R.; Toki, W. H.; Jasper, H.; Petzold, A.; Spaan, B.; Kobel, M. J.; Schubert, K. R.; Schwierz, R.; Bernard, D.; Verderi, M.; Clark, P. J.; Playfer, S.; Watson, J. E.; Andreotti, M.; Bettoni, D.; Bozzi, C.; Calabrese, R.; Cecchi, A.; Cibinetto, G.; Fioravanti, E.; Franchini, P.; Garzia, I.; Luppi, E.; Munerato, M.; Negrini, M.; Petrella, A.; Piemontese, L.; Baldini-Ferroli, R.; Calcaterra, A.; de Sangro, R.; Finocchiaro, G.; Nicolaci, M.; Pacetti, S.; Patteri, P.; Peruzzi, I. M.; Piccolo, M.; Rama, M.; Zallo, A.; Contri, R.; Guido, E.; Lo Vetere, M.; Monge, M. R.; Passaggio, S.; Patrignani, C.; Robutti, E.; Bhuyan, B.; Prasad, V.; Lee, C. L.; Morii, M.; Edwards, A. J.; Adametz, A.; Marks, J.; Uwer, U.; Bernlochner, F. U.; Ebert, M.; Lacker, H. M.; Lueck, T.; Volk, A.; Dauncey, P. D.; Tibbetts, M.; Behera, P. K.; Mallik, U.; Chen, C.; Cochran, J.; Crawley, H. B.; Meyer, W. T.; Prell, S.; Rosenberg, E. I.; Rubin, A. E.; Gritsan, A. V.; Guo, Z. J.; Arnaud, N.; Davier, M.; Derkach, D.; Firmino da Costa, J.; Grosdidier, G.; Le Diberder, F.; Lutz, A. M.; Malaescu, B.; Perez, A.; Roudeau, P.; Schune, M. H.; Serrano, J.; Sordini, V.; Stocchi, A.; Wang, L.; Wormser, G.; Lange, D. J.; Wright, D. M.; Bingham, I.; Chavez, C. A.; Coleman, J. P.; Fry, J. R.; Gabathuler, E.; Hutchcroft, D. E.; Payne, D. J.; Touramanis, C.; Bevan, A. J.; di Lodovico, F.; Sacco, R.; Sigamani, M.; Cowan, G.; Paramesvaran, S.; Wren, A. C.; Brown, D. N.; Davis, C. L.; Denig, A. G.; Fritsch, M.; Gradl, W.; Hafner, A.; Alwyn, K. E.; Bailey, D.; Barlow, R. J.; Jackson, G.; Lafferty, G. D.; Anderson, J.; Cenci, R.; Jawahery, A.; Roberts, D. A.; Simi, G.; Tuggle, J. M.; Dallapiccola, C.; Salvati, E.; Cowan, R.; Dujmic, D.; Sciolla, G.; Zhao, M.; Lindemann, D.; Patel, P. M.; Robertson, S. H.; Schram, M.; Biassoni, P.; Lazzaro, A.; Lombardo, V.; Palombo, F.; Stracka, S.; Cremaldi, L.; Godang, R.; Kroeger, R.; Sonnek, P.; Summers, D. J.; Nguyen, X.; Simard, M.; Taras, P.; de Nardo, G.; Monorchio, D.; Onorato, G.; Sciacca, C.; Raven, G.; Snoek, H. L.; Jessop, C. P.; Knoepfel, K. J.; Losecco, J. M.; Wang, W. F.; Corwin, L. A.; Honscheid, K.; Kass, R.; Blount, N. L.; Brau, J.; Frey, R.; Igonkina, O.; Kolb, J. A.; Rahmat, R.; Sinev, N. B.; Strom, D.; Strube, J.; Torrence, E.; Castelli, G.; Feltresi, E.; Gagliardi, N.; Margoni, M.; Morandin, M.; Posocco, M.; Rotondo, M.; Simonetto, F.; Stroili, R.; Ben-Haim, E.; Bomben, M.; Bonneaud, G. R.; Briand, H.; Calderini, G.; Chauveau, J.; Hamon, O.; Leruste, Ph.; Marchiori, G.; Ocariz, J.; Prendki, J.; Sitt, S.; Biasini, M.; Manoni, E.; Rossi, A.; Angelini, C.; Batignani, G.; Bettarini, S.; Carpinelli, M.; Casarosa, G.; Cervelli, A.; Forti, F.; Giorgi, M. A.; Lusiani, A.; Neri, N.; Paoloni, E.; Rizzo, G.; Walsh, J. J.; Lopes Pegna, D.; Lu, C.; Olsen, J.; Smith, A. J. S.; Telnov, A. V.; Anulli, F.; Baracchini, E.; Cavoto, G.; Faccini, R.; Ferrarotto, F.; Ferroni, F.; Gaspero, M.; Li Gioi, L.; Mazzoni, M. A.; Piredda, G.; Renga, F.; Buenger, C.; Hartmann, T.; Leddig, T.; Schröder, H.; Waldi, R.; Adye, T.; Olaiya, E. O.; Wilson, F. F.; Emery, S.; Hamel de Monchenault, G.; Vasseur, G.; Yèche, Ch.; Allen, M. T.; Aston, D.; Bard, D. J.; Bartoldus, R.; Benitez, J. F.; Cartaro, C.; Convery, M. R.; Dorfan, J.; Dubois-Felsmann, G. P.; Dunwoodie, W.; Field, R. C.; Franco Sevilla, M.; Fulsom, B. G.; Gabareen, A. M.; Graham, M. T.; Grenier, P.; Hast, C.; Innes, W. R.; Kelsey, M. H.; Kim, H.; Kim, P.; Kocian, M. L.; Leith, D. W. G. S.; Lewis, P.; Li, S.; Lindquist, B.; Luitz, S.; Luth, V.; Lynch, H. L.; Macfarlane, D. B.; Muller, D. R.; Neal, H.; Nelson, S.; O'Grady, C. P.; Ofte, I.; Perl, M.; Pulliam, T.; Ratcliff, B. N.; Roodman, A.; Salnikov, A. A.; Santoro, V.; Schindler, R. H.; Schwiening, J.; Snyder, A.; Su, D.; Sullivan, M. K.; Sun, S.; Suzuki, K.; Thompson, J. M.; Va'Vra, J.; Wagner, A. P.; Weaver, M.; Wisniewski, W. J.; Wittgen, M.; Wright, D. H.; Wulsin, H. W.; Yarritu, A. K.; Young, C. C.; Ziegler, V.; Chen, X. R.; Park, W.; Purohit, M. V.; White, R. M.; Wilson, J. R.; Randle-Conde, A.; Sekula, S. J.; Bellis, M.; Burchat, P. R.; Miyashita, T. S.; Ahmed, S.; Alam, M. S.; Ernst, J. A.; Pan, B.; Saeed, M. A.; Zain, S. B.; Guttman, N.; Soffer, A.; Lund, P.; Spanier, S. M.; Eckmann, R.; Ritchie, J. L.; Ruland, A. M.; Schilling, C. J.; Schwitters, R. F.; Wray, B. C.; Izen, J. M.; Lou, X. C.; Bianchi, F.; Gamba, D.; Pelliccioni, M.; Lanceri, L.; Vitale, L.; Lopez-March, N.; Martinez-Vidal, F.; Oyanguren, A.; Ahmed, H.; Albert, J.; Banerjee, Sw.; Choi, H. H. F.; Hamano, K.; King, G. J.; Kowalewski, R.; Lewczuk, M. J.; Lindsay, C.; Nugent, I. M.; Roney, J. M.; Sobie, R. J.; Gershon, T. J.; Harrison, P. F.; Latham, T. E.; Puccio, E. M. T.; Band, H. R.; Dasu, S.; Flood, K. T.; Pan, Y.; Prepost, R.; Vuosalo, C. O.; Wu, S. L.

    2011-09-01

    We study the reactions e+e-→e+e-η(') in the single-tag mode and measure the γγ*→η(') transition form factors in the momentum-transfer range from 4 to 40GeV2. The analysis is based on 469fb-1 of integrated luminosity collected at PEP-II with the BABAR detector at e+e- center-of-mass energies near 10.6 GeV.

  10. The Storage and Composition of Inflected Forms in Adult-Learned Second Language: A Study of the Influence of Length of Residence, Age of Arrival, Sex, and Other Factors

    ERIC Educational Resources Information Center

    Babcock, Laura; Stowe, John C.; Maloof, Christopher J.; Brovetto, Claudia; Ullman, Michael T.

    2012-01-01

    It remains unclear whether adult-learned second language (L2) depends on similar or different neurocognitive mechanisms as those involved in first language (L1). We examined whether English past tense forms are computed similarly or differently by L1 and L2 English speakers, and what factors might affect this: regularity (regular vs. irregular…

  11. Baryon transition form factors at the pole

    DOE PAGES

    Tiator, L.; Döring, M.; Workman, R. L.; ...

    2016-12-21

    Electromagnetic resonance properties are uniquely defined at the pole and do not depend on the separation of the resonance from background or the decay channel. Photon-nucleon branching ratios are nowadays often quoted at the pole, and we generalize the considerations to the case of virtual photons. In this paper, we derive and compare relations for nucleon to baryon transition form factors both for the Breit-Wigner and the pole positions. Using the MAID2007 and SAID SM08 partial wave analyses of pion electroproduction data, we compare themore » $$G_M$$, $$G_E$$, and $$G_C$$ form factors for the $$\\Delta(1232)$$ resonance excitation at the Breit-Wigner resonance and pole positions up to $Q^2=5$ GeV$^2$. We also explore the $E/M$ and $S/M$ ratios as functions of $Q^2$. Finally, for pole and residue extraction, we apply the Laurent + Pietarinen method.« less

  12. Extraction of the neutron magnetic form factor from quasielastic 3He→(e→,e') at Q2=0.1-0.6(GeV/c)2

    NASA Astrophysics Data System (ADS)

    Anderson, B.; Auberbach, L.; Averett, T.; Bertozzi, W.; Black, T.; Calarco, J.; Cardman, L.; Cates, G. D.; Chai, Z. W.; Chen, J. P.; Choi, Seonho; Chudakov, E.; Churchwell, S.; Corrado, G. S.; Crawford, C.; Dale, D.; Deur, A.; Djawotho, P.; Dutta, D.; Finn, J. M.; Gao, H.; Gilman, R.; Glamazdin, A. V.; Glashausser, C.; Glöckle, W.; Golak, J.; Gomez, J.; Gorbenko, V. G.; Hansen, J.-O.; Hersman, F. W.; Higinbotham, D. W.; Holmes, R.; Howell, C. R.; Hughes, E.; Humensky, B.; Incerti, S.; Jager, C. W. De; Jensen, J. S.; Jiang, X.; Jones, C. E.; Jones, M.; Kahl, R.; Kamada, H.; Kievsky, A.; Kominis, I.; Korsch, W.; Kramer, K.; Kumbartzki, G.; Kuss, M.; Lakuriqi, E.; Liang, M.; Liyanage, N.; Lerose, J.; Malov, S.; Margaziotis, D. J.; Martin, J. W.; McCormick, K.; McKeown, R. D.; McIlhany, K.; Meziani, Z.-E.; Michaels, R.; Miller, G. W.; Mitchell, J.; Nanda, S.; Pace, E.; Pavlin, T.; Petratos, G. G.; Pomatsalyuk, R. I.; Pripstein, D.; Prout, D.; Ransome, R. D.; Roblin, Y.; Rvachev, M.; Saha, A.; Salmè, G.; Schnee, M.; Seely, J.; Shin, T.; Slifer, K.; Souder, P. A.; Strauch, S.; Suleiman, R.; Sutter, M.; Tipton, B.; Todor, L.; Viviani, M.; Vlahovic, B.; Watson, J.; Williamson, C. F.; Witała, H.; Wojtsekhowski, B.; Xiong, F.; Xu, W.; Yeh, J.; Żołnierczuk, P.

    2007-03-01

    We have measured the transverse asymmetry AT' in the quasielastic 3He→(e→,e') process with high precision at Q2 values from 0.1 to 0.6(GeV/c)2. The neutron magnetic form factor GMn was extracted at Q2 values of 0.1 and 0.2(GeV/c)2 using a nonrelativistic Faddeev calculation which includes both final-state interactions (FSI) and meson-exchange currents (MEC). Theoretical uncertainties due to the FSI and MEC effects were constrained with a precision measurement of the spin-dependent asymmetry in the threshold region of 3He→(e→,e'). We also extracted the neutron magnetic form factor GMn at Q2 values of 0.3 to 0.6(GeV/c)2 based on plane wave impulse approximation calculations.

  13. Baryon transition form factors at the pole

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tiator, L.; Döring, M.; Workman, R. L.

    Electromagnetic resonance properties are uniquely defined at the pole and do not depend on the separation of the resonance from background or the decay channel. Photon-nucleon branching ratios are nowadays often quoted at the pole, and we generalize the considerations to the case of virtual photons. In this paper, we derive and compare relations for nucleon to baryon transition form factors both for the Breit-Wigner and the pole positions. Using the MAID2007 and SAID SM08 partial wave analyses of pion electroproduction data, we compare themore » $$G_M$$, $$G_E$$, and $$G_C$$ form factors for the $$\\Delta(1232)$$ resonance excitation at the Breit-Wigner resonance and pole positions up to $Q^2=5$ GeV$^2$. We also explore the $E/M$ and $S/M$ ratios as functions of $Q^2$. Finally, for pole and residue extraction, we apply the Laurent + Pietarinen method.« less

  14. A note on NMHV form factors from the Graßmannian and the twistor string

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Meidinger, David; Nandan, Dhritiman; Penante, Brenda

    In this note we investigate Graßmannian formulas for form factors of the chiral part of the stress-tensor multiplet in N = 4 superconformal Yang-Mills theory. We present an all-n contour for the G(3, n + 2) Graßmannian integral of NMHV form factors derived from on-shell diagrams and the BCFW recursion relation. In addition, we study other G(3, n + 2) formulas obtained from the connected prescription introduced recently. We find a recursive expression for all n and study its properties. For n ≥ 6, our formula has the same recursive structure as its amplitude counterpart, making its soft behaviour manifest.more » Finally, we explore the connection between the two Graßmannian formulations, using the global residue theorem, and find that it is much more intricate compared to scattering amplitudes.« less

  15. B→πll Form Factors for New Physics Searches from Lattice QCD.

    PubMed

    Bailey, Jon A; Bazavov, A; Bernard, C; Bouchard, C M; DeTar, C; Du, Daping; El-Khadra, A X; Freeland, E D; Gámiz, E; Gottlieb, Steven; Heller, U M; Kronfeld, A S; Laiho, J; Levkova, L; Liu, Yuzhi; Lunghi, E; Mackenzie, P B; Meurice, Y; Neil, E; Qiu, Si-Wei; Simone, J N; Sugar, R; Toussaint, D; Van de Water, R S; Zhou, Ran

    2015-10-09

    The rare decay B→πℓ^{+}ℓ^{-} arises from b→d flavor-changing neutral currents and could be sensitive to physics beyond the standard model. Here, we present the first ab initio QCD calculation of the B→π tensor form factor f_{T}. Together with the vector and scalar form factors f_{+} and f_{0} from our companion work [J. A. Bailey et al., Phys. Rev. D 92, 014024 (2015)], these parametrize the hadronic contribution to B→π semileptonic decays in any extension of the standard model. We obtain the total branching ratio BR(B^{+}→π^{+}μ^{+}μ^{-})=20.4(2.1)×10^{-9} in the standard model, which is the most precise theoretical determination to date, and agrees with the recent measurement from the LHCb experiment [R. Aaij et al., J. High Energy Phys. 12 (2012) 125].

  16. Near-threshold neutral pion electroproduction at high momentum transfers and generalized form factors

    NASA Astrophysics Data System (ADS)

    Khetarpal, P.; Stoler, P.; Aznauryan, I. G.; Kubarovsky, V.; Adhikari, K. P.; Adikaram, D.; Aghasyan, M.; Amaryan, M. J.; Anderson, M. D.; Anefalos Pereira, S.; Anghinolfi, M.; Avakian, H.; Baghdasaryan, H.; Ball, J.; Baltzell, N. A.; Battaglieri, M.; Batourine, V.; Bedlinskiy, I.; Biselli, A. S.; Bono, J.; Boiarinov, S.; Briscoe, W. J.; Brooks, W. K.; Burkert, V. D.; Carman, D. S.; Celentano, A.; Charles, G.; Cole, P. L.; Contalbrigo, M.; Crede, V.; D'Angelo, A.; Dashyan, N.; De Vita, R.; De Sanctis, E.; Deur, A.; Djalali, C.; Doughty, D.; Dugger, M.; Dupre, R.; Egiyan, H.; El Alaoui, A.; El Fassi, L.; Eugenio, P.; Fedotov, G.; Fegan, S.; Fersch, R.; Fleming, J. A.; Fradi, A.; Gabrielyan, M. Y.; Garçon, M.; Gevorgyan, N.; Gilfoyle, G. P.; Giovanetti, K. L.; Girod, F. X.; Goetz, J. T.; Gohn, W.; Golovatch, E.; Gothe, R. W.; Griffioen, K. A.; Guegan, B.; Guidal, M.; Guo, L.; Hafidi, K.; Hakobyan, H.; Hanretty, C.; Harrison, N.; Hicks, K.; Ho, D.; Holtrop, M.; Hyde, C. E.; Ilieva, Y.; Ireland, D. G.; Ishkhanov, B. S.; Isupov, E. L.; Jo, H. S.; Joo, K.; Keller, D.; Khandaker, M.; Kim, A.; Kim, W.; Klein, F. J.; Koirala, S.; Kubarovsky, A.; Kuleshov, S. V.; Kvaltine, N. D.; Lewis, S.; Livingston, K.; Lu, H. Y.; MacGregor, I. J. D.; Mao, Y.; Martinez, D.; Mayer, M.; McKinnon, B.; Meyer, C. A.; Mineeva, T.; Mirazita, M.; Mokeev, V.; Montgomery, R. A.; Moutarde, H.; Munevar, E.; Munoz Camacho, C.; Nadel-Turonski, P.; Nasseripour, R.; Niccolai, S.; Niculescu, G.; Niculescu, I.; Osipenko, M.; Ostrovidov, A. I.; Pappalardo, L. L.; Paremuzyan, R.; Park, K.; Park, S.; Pasyuk, E.; Phelps, E.; Phillips, J. J.; Pisano, S.; Pogorelko, O.; Pozdniakov, S.; Price, J. W.; Procureur, S.; Protopopescu, D.; Puckett, A. J. R.; Raue, B. A.; Ricco, G.; Rimal, D.; Ripani, M.; Rosner, G.; Rossi, P.; Sabatié, F.; Saini, M. S.; Salgado, C.; Saylor, N. A.; Schott, D.; Schumacher, R. A.; Seder, E.; Seraydaryan, H.; Sharabian, Y. G.; Smith, G. D.; Sober, D. I.; Sokhan, D.; Stepanyan, S. S.; Stepanyan, S.; Strakovsky, I. I.; Strauch, S.; Taiuti, M.; Tang, W.; Taylor, C. E.; Tkachenko, S.; Ungaro, M.; Vernarsky, B.; Voskanyan, H.; Voutier, E.; Walford, N. K.; Weinstein, L. B.; Weygand, D. P.; Wood, M. H.; Zachariou, N.; Zhang, J.; Zhao, Z. W.; Zonta, I.

    2013-04-01

    We report the measurement of near-threshold neutral pion electroproduction cross sections and the extraction of the associated structure functions on the proton in the kinematic range Q2 from 2 to 4.5 GeV2 and W from 1.08 to 1.16 GeV. These measurements allow us to access the dominant pion-nucleon s-wave multipoles E0+ and S0+ in the near-threshold region. In the light-cone sum-rule framework (LCSR), these multipoles are related to the generalized form factors G1π0p(Q2) and G2π0p(Q2). The data are compared to these generalized form factors and the results for G1π0p(Q2) are found to be in good agreement with the LCSR predictions, but the level of agreement with G2π0p(Q2) is poor.

  17. Measurement of the generalized form factors near threshold via γ*p→nπ+ at high Q2

    NASA Astrophysics Data System (ADS)

    Park, K.; Gothe, R. W.; Adhikari, K. P.; Adikaram, D.; Anghinolfi, M.; Baghdasaryan, H.; Ball, J.; Battaglieri, M.; Batourine, V.; Bedlinskiy, I.; Bennett, R. P.; Biselli, A. S.; Bookwalter, C.; Boiarinov, S.; Branford, D.; Briscoe, W. J.; Brooks, W. K.; Burkert, V. D.; Carman, D. S.; Celentano, A.; Chandavar, S.; Charles, G.; Cole, P. L.; Contalbrigo, M.; Crede, V.; D'Angelo, A.; Daniel, A.; Dashyan, N.; De Vita, R.; De Sanctis, E.; Deur, A.; Djalali, C.; Doughty, D.; Dupre, R.; El Alaoui, A.; El Fassi, L.; Eugenio, P.; Fedotov, G.; Fradi, A.; Gabrielyan, M. Y.; Gevorgyan, N.; Gilfoyle, G. P.; Giovanetti, K. L.; Girod, F. X.; Goetz, J. T.; Gohn, W.; Golovatch, E.; Graham, L.; Griffioen, K. A.; Guidal, M.; Guo, L.; Hafidi, K.; Hakobyan, H.; Hanretty, C.; Heddle, D.; Hicks, K.; Holtrop, M.; Hyde, C. E.; Ilieva, Y.; Ireland, D. G.; Ishkhanov, B. S.; Isupov, E. L.; Jenkins, D.; Jo, H. S.; Joo, K.; Kalantarians, N.; Khandaker, M.; Khetarpal, P.; Kim, A.; Kim, W.; Klein, A.; Klein, F. J.; Kubarovsky, A.; Kubarovsky, V.; Kuhn, S. E.; Kuleshov, S. V.; Kvaltine, N. D.; Livingston, K.; Lu, H. Y.; MacGregor, I. J. D.; Markov, N.; Mayer, M.; McKinnon, B.; Mestayer, M. D.; Meyer, C. A.; Mineeva, T.; Mirazita, M.; Mokeev, V.; Moutarde, H.; Munevar, E.; Nadel-Turonski, P.; Nasseripour, R.; Niccolai, S.; Niculescu, G.; Niculescu, I.; Osipenko, M.; Ostrovidov, A. I.; Paolone, M.; Pappalardo, L.; Paremuzyan, R.; Park, S.; Pereira, S. Anefalos; Phelps, E.; Pisano, S.; Pogorelko, O.; Pozdniakov, S.; Price, J. W.; Procureur, S.; Prok, Y.; Ricco, G.; Rimal, D.; Ripani, M.; Ritchie, B. G.; Rosner, G.; Rossi, P.; Sabatié, F.; Saini, M. S.; Salgado, C.; Schott, D.; Schumacher, R. A.; Seraydaryan, H.; Sharabian, Y. G.; Smith, E. S.; Smith, G. D.; Sober, D. I.; Sokhan, D.; Stepanyan, S. S.; Stepanyan, S.; Stoler, P.; Strakovsky, I. I.; Strauch, S.; Taiuti, M.; Tang, W.; Taylor, C. E.; Tian, Y.; Tkachenko, S.; Trivedi, A.; Ungaro, M.; Vernarsky, B.; Vlassov, A. V.; Voutier, E.; Watts, D. P.; Weygand, D. P.; Wood, M. H.; Zachariou, N.; Zhao, B.; Zhao, Z. W.

    2012-03-01

    We report the first extraction of the pion-nucleon multipoles near the production threshold for the nπ+ channel at relatively high momentum transfer (Q2 up to 4.2 GeV2). The dominance of the s-wave transverse multipole (E0+), expected in this region, allowed us to access the generalized form factor G1 within the light-cone sum-rule (LCSR) framework as well as the axial form factor GA. The data analyzed in this work were collected by the nearly 4π CEBAF Large Acceptance Spectrometer (CLAS) using a 5.754-GeV electron beam on a proton target. The differential cross section and the π-N multipole E0+/GD were measured using two different methods, the LCSR and a direct multipole fit. The results from the two methods are found to be consistent and almost Q2 independent.

  18. A note on NMHV form factors from the Graßmannian and the twistor string

    DOE PAGES

    Meidinger, David; Nandan, Dhritiman; Penante, Brenda; ...

    2017-09-06

    In this note we investigate Graßmannian formulas for form factors of the chiral part of the stress-tensor multiplet in N = 4 superconformal Yang-Mills theory. We present an all-n contour for the G(3, n + 2) Graßmannian integral of NMHV form factors derived from on-shell diagrams and the BCFW recursion relation. In addition, we study other G(3, n + 2) formulas obtained from the connected prescription introduced recently. We find a recursive expression for all n and study its properties. For n ≥ 6, our formula has the same recursive structure as its amplitude counterpart, making its soft behaviour manifest.more » Finally, we explore the connection between the two Graßmannian formulations, using the global residue theorem, and find that it is much more intricate compared to scattering amplitudes.« less

  19. Mismatch repair factor MSH2-MSH3 binds and alters the conformation of branched DNA structures predicted to form during genetic recombination.

    PubMed

    Surtees, Jennifer A; Alani, Eric

    2006-07-14

    Genetic studies in Saccharomyces cerevisiae predict that the mismatch repair (MMR) factor MSH2-MSH3 binds and stabilizes branched recombination intermediates that form during single strand annealing and gene conversion. To test this model, we constructed a series of DNA substrates that are predicted to form during these recombination events. We show in an electrophoretic mobility shift assay that S. cerevisiae MSH2-MSH3 specifically binds branched DNA substrates containing 3' single-stranded DNA and that ATP stimulates its release from these substrates. Chemical footprinting analyses indicate that MSH2-MSH3 specifically binds at the double-strand/single-strand junction of branched substrates, alters its conformation and opens up the junction. Therefore, MSH2-MSH3 binding to its substrates creates a unique nucleoprotein structure that may signal downstream steps in repair that include interactions with MMR and nucleotide excision repair factors.

  20. Allometry and stoichiometry of unicellular, colonial and multicellular phytoplankton.

    PubMed

    Beardall, John; Allen, Drew; Bragg, Jason; Finkel, Zoe V; Flynn, Kevin J; Quigg, Antonietta; Rees, T Alwyn V; Richardson, Anthony; Raven, John A

    2009-01-01

    Phytoplankton life forms, including unicells, colonies, pseudocolonies, and multicellular organisms, span a huge size range. The smallest unicells are less than 1 microm3 (e.g. cyanobacteria), while large unicellular diatoms may attain 10(9) microm3, being visible to the naked eye. Phytoplankton includes chemo-organotrophic unicells, colonies and multicellular organisms that depend on symbionts or kleptoplastids for their capacity to photosynthesize. Analyses of physical (transport within cells, diffusion boundary layers, package effect, turgor, and vertical movements) and biotic (grazing, viruses and other parasitoids) factors indicate potential ecological constraints and opportunities that differ among the life forms. There are also variations among life forms in elemental stoichiometry and in allometric relations between biovolume and specific growth. While many of these factors probably have ecological and evolutionary significance, work is needed to establish those that are most important, warranting explicit description in models. Other factors setting limitations on growth rate (selecting slow-growing species) await elucidation.

  1. $$B\\to\\pi\\ell\\ell$$ Form Factors for New-Physics Searches from Lattice QCD

    DOE PAGES

    Bailey, Jon A.

    2015-10-07

    The rare decay B→πℓ +ℓ - arises from b→d flavor-changing neutral currents and could be sensitive to physics beyond the standard model. Here, we present the first ab initio QCD calculation of the B→π tensor form factor f T. Together with the vector and scalar form factors f + and f 0 from our companion work [J. A. Bailey et al., Phys. Rev. D 92, 014024 (2015)], these parametrize the hadronic contribution to B→π semileptonic decays in any extension of the standard model. We obtain the total branching ratio BR(B +→π +μ +μ -)=20.4(2.1)×10 -9 in the standard model, whichmore » is the most precise theoretical determination to date, and agrees with the recent measurement from the LHCb experiment [R. Aaij et al., J. High Energy Phys. 12 (2012) 125].« less

  2. Electromagnetic Charge Radius of the Pion at High Precision

    NASA Astrophysics Data System (ADS)

    Ananthanarayan, B.; Caprini, Irinel; Das, Diganta

    2017-09-01

    We present a determination of the pion charge radius from high precision data on the pion vector form factor from both timelike and spacelike regions, using a novel formalism based on analyticity and unitarity. At low energies, instead of the poorly known modulus of the form factor, we use its phase, known with high accuracy from Roy equations for π π elastic scattering via the Fermi-Watson theorem. We use also the values of the modulus at several higher timelike energies, where the data from e+e- annihilation and τ decay are mutually consistent, as well as the most recent measurements at spacelike momenta. The experimental uncertainties are implemented by Monte Carlo simulations. The results, which do not rely on a specific parametrization, are optimal for the given input information and do not depend on the unknown phase of the form factor above the first inelastic threshold. Our prediction for the charge radius of the pion is rπ=(0.657 ±0.003 ) fm , which amounts to an increase in precision by a factor of about 2.7 compared to the Particle Data Group average.

  3. Genetics, environmental factors and the emerging role of epigenetics in neurodegenerative diseases.

    PubMed

    Migliore, Lucia; Coppedè, Fabio

    2009-07-10

    In the present review we summarize recent advances in the understanding of the interaction between genetics and environmental factors involved in complex multi-factorial neurodegenerative disorders such as Alzheimer's disease (AD), Parkinson's disease (PD) and Amyotrophic Lateral Sclerosis (ALS). The discovery of several genes responsible for the familial forms has led to a better comprehension of the molecular pathways involved in the selective neuronal degeneration which is specific for each of these disorders. However, the vast majority of the cases occurs as sporadic forms, likely resulting from complex gene-gene and gene-environment interplay. Several environmental factors, including, pesticides, metals, head injuries, lifestyles and dietary habits have been associated with increased disease risk or even with protection. Hundreds of genetic variants have been investigated as possible risk factors for the sporadic forms, but results are often conflicting, not repeated or inconclusive. New approaches to environmental health research are revealing us that at the basis there could be chemically induced changes in gene regulation and emphasise the importance of understanding the susceptibility of the human epigenome to dietary and other environmental effects.

  4. A murine model of acute myeloid leukemia with Evi1 overexpression and autocrine stimulation by an intracellular form of GM-CSF in DA-3 cells.

    PubMed

    Cardona, Maria E; Simonson, Oscar E; Oprea, Iulian I; Moreno, Pedro M D; Silva-Lara, Maria F; Mohamed, Abdalla J; Christensson, Birger; Gahrton, Gösta; Dilber, M Sirac; Smith, C I Edvard; Arteaga, H Jose

    2016-01-01

    The poor treatment response of acute myeloid leukemia (AML) overexpressing high-risk oncogenes such as EVI1, demands specific animal models for new treatment evaluations. Evi1 is a common site of activating integrations in murine leukemia virus (MLV)-induced AML and in retroviral and lentiviral gene-modified HCS. Still, a model of overt AML induced by Evi1 has not been generated. Cell lines from MLV-induced AML are growth factor-dependent and non-transplantable. Hence, for the leukemia maintenance in the infected animals, a growth factor source such as chronic immune response has been suggested. We have investigated whether these leukemias are transplantable if provided with growth factors. We show that the Evi1(+)DA-3 cells modified to express an intracellular form of GM-CSF, acquired growth factor independence and transplantability and caused an overt leukemia in syngeneic hosts, without increasing serum GM-CSF levels. We propose this as a general approach for modeling different forms of high-risk human AML using similar cell lines.

  5. Audit of admission to medical school: II--Shortlisting and interviews.

    PubMed Central

    McManus, I C; Richards, P

    1984-01-01

    Analysis of shortlisting of applicants for interview at St Mary's Hospital Medical School showed that factor analysis could reduce the selection criteria to three independent scales--"academic ability," "interests," and "community service"--all of which contributed to the interview decision. Early applicants scored more highly on all three factors but were still at a greater advantage in selection for interview than would have been predicted. The dean's judgment of priority for interview from the UCCA form was found to predict a candidate's chance of acceptance at other medical schools besides St Mary's. Analysis of interviewing showed high correlations among interviewers in their assessments, although there was evidence of influence by the chairmen. Factor analysis showed three major factors--academic suitability, non-academic suitability, and health--of which non academic suitability was the major determinant of interview success. Non academic suitability was related to personality (high extraversion and low psychoticism) and to the choices made on the UCCA form. The system of admission interviews enabled greater emphasis to be put on broader interests and achievements than if selection had been on the basis of UCCA application form alone. PMID:6437522

  6. Demographic Factors, Personality, and Ability as Predictors of Learning Approaches

    ERIC Educational Resources Information Center

    Xie, Qiuzhi; Zhang, Li-fang

    2015-01-01

    This study investigated the extent to which learning approaches can be accounted for by personal factors (i.e., demographics, ability, and personality). The participants were 443 students in a university in mainland China. The Revised Two-factor Study Process Questionnaire, the NEO Five-Factor Inventory-3, and the short form of Raven's Advanced…

  7. A Hilbert Space Geometric Representation of Shared Awareness and Joint Decision Making

    ERIC Educational Resources Information Center

    Canan, Mustafa

    2017-01-01

    Two people in the same situation may ascribe very different meanings to their experiences. They will form different awareness, reacting differently to shared information. Various factors can give rise to this behavior. These factors include, but are not limited to, prior knowledge, training, biases, cultural factors, social factors, team vs.…

  8. Promoting Self-Esteem in Adolescents: The Influence of Wellness Factors

    ERIC Educational Resources Information Center

    Myers, Jane E.; Willse, John T.; Villalba, Jose A.

    2011-01-01

    To assess the extent to which holistic wellness factors are predictive of self-esteem, the authors administered the Coopersmith Self-Esteem Inventories, School Form (Coopersmith, 2002), and the Five Factor Wellness Inventory (Myers & Sweeney, 2005a) to 225 adolescents ages 15 to 17 years. Wellness factors (Coping Self, Social Self, and…

  9. Renal-Stone Risk Assessment During Space Shuttle Flights

    NASA Technical Reports Server (NTRS)

    Whitson, Peggy A.; Pietrzyk, Robert A.; Pak, Charles Y. C.

    1996-01-01

    The metabolic and environmental factors influencing renal stone formation before, during, and after Space Shuttle flights were assessed. We established the contributing roles of dietary factors in relationship to the urinary risk factors associated with renal stone formation. 24-hr urine samples were collected prior to, during space flight, and following landing. Urinary factors associated with renal stone formation were analyzed and the relative urinary supersaturation ratios of calcium oxalate, calcium phosphate (brushite), sodium urate, struvite and uric acid were calculated. Food and fluid consumption was recorded for a 48-hr period ending with the urine collection. Urinary composition changed during flight to favor the crystallization of stone-forming salts. Factors that contributed to increased potential for stone formation during space flight were significant reductions in urinary pH and increases in urinary calcium. Urinary output and citrate, a potent inhibitor of calcium-containing stones, were slightly reduced during space flight. Dietary intakes were significantly reduced for a number of variables, including fluid, energy, protein, potassium, phosphorus and magnesium. This is the first in-flight characterization of the renal stone forming potential in astronauts. With the examination of urinary components and nutritional factors, it was possible to determine the factors that contributed to increased risk or protected from risk. In spite of the protective components, the negative contributions to renal stone risk predominated and resulted in a urinary environment that favored the supersaturation of stone-forming salts. The importance of the hypercalciuria was noted since renal excretion was high relative to the intake.

  10. Renal stone risk assessment during Space Shuttle flights

    NASA Technical Reports Server (NTRS)

    Whitson, P. A.; Pietrzyk, R. A.; Pak, C. Y.

    1997-01-01

    PURPOSE: The metabolic and environmental factors influencing renal stone formation before, during, and after Space Shuttle flights were assessed. We established the contributing roles of dietary factors in relationship to the urinary risk factors associated with renal stone formation. MATERIALS AND METHODS: 24-hr. urine samples were collected prior to, during space flight, and following landing. Urinary and dietary factors associated with renal stone formation were analyzed and the relative urinary supersaturation of calcium oxalate, calcium phosphate (brushite), sodium urate, struvite and uric acid were calculated. RESULTS: Urinary composition changed during flight to favor the crystallization of calcium-forming salts. Factors that contributed to increased potential for stone formation during space flight were significant reductions in urinary pH and increases in urinary calcium. Urinary output and citrate, a potent inhibitor of calcium-containing stones, were slightly reduced during space flight. Dietary intakes were significantly reduced for a number of variables, including fluid, energy, protein, potassium, phosphorus and magnesium. CONCLUSIONS: This is the first in-flight characterization of the renal stone forming potential in astronauts. With the examination of urinary components and nutritional factors, it was possible to determine the factors that contributed to increased risk or protected from risk. In spite of the protective components, the negative contributions to renal stone risk predominated and resulted in a urinary environment that favored the supersaturation of stone-forming salts. Dietary and pharmacologic therapies need to be assessed to minimize the potential for renal stone formation in astronauts during/after space flight.

  11. Prospective associations of psychosocial adversity in childhood with risk factors for cardiovascular disease in adulthood: the MRC National Survey of Health and Development.

    PubMed

    Anderson, Emma L; Caleyachetty, Rishi; Stafford, Mai; Kuh, Diana; Hardy, Rebecca; Lawlor, Debbie A; Fraser, Abigail; Howe, Laura D

    2017-09-07

    Studies assessing associations of childhood psychosocial adversity (e.g. sexual abuse, physical neglect, parental death), as opposed to socioeconomic adversity, with cardiovascular disease (CVD) risk factors in adulthood are scarce. We aimed to assess associations of various forms of psychosocial adversity and cumulative adversity in childhood, with multiple CVD risk factors in mid-life. Participants were from the MRC National Survey of Health and Development. Childhood psychosocial risk factors were reported prospectively by parents from 1950-1957, and retrospectively by participants at mean age 43 years in 1989. CVD risk factors were assessed at mean age 60-64 years in 2006-2011. Associations of a summary score of total psychosocial adversity and CVD risk in adulthood were assessed. There was no consistent evidence that cumulative psychosocial adversity, nor any specific form of psychosocial adversity in childhood, was associated with CVD risk factors in late adulthood. There was some evidence that parental death in the first 15 years was associated with higher SBP (Beta: 0.23, 95% confidence interval: 0.06 to 0.40, P=0.01) and DBP (Beta: 0.15, 95% confidence interval: -0.01 to 0.32, P=0.07). We found no evidence that exposure to greater psychosocial adversity, or specific forms of psychosocial adversity during childhood is associated with adult CVD risk factors. Further large population studies are needed to clarify whether parental death is associated with higher systolic and diastolic blood pressure.

  12. Efficiency of Geiger-Muller Counter; EFICIENCIA DE UN CONTADOR GEIGER-MULLER

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rapaport, J.

    1960-05-01

    Factors affecting the efflciency of a Geiger-Muller counter are given, and the experimental techniques used to measure each of these factors are described. The values obtained for each factor are shown in graphic and tabular form. (J.S.R.)

  13. The influence of process and patient factors on the recall of consent information in mentally competent patients undergoing surgery for neck of femur fractures.

    PubMed

    Khan, S K; Karuppaiah, K; Bajwa, A S

    2012-07-01

    Informed consent is an ethical and legal prerequisite for major surgical procedures. Recent literature has identified 'poor consent' as a major cause of litigation in trauma cases. We aimed to investigate the patient and process factors that influence consent information recall in mentally competent patients (abbreviated mental test score [AMTS] ≥6) presenting with neck of femur (NOF) fractures. A prospective study was conducted at a tertiary unit. Fifty NOF patients (cases) and fifty total hip replacement (THR) patients (controls) were assessed for process factors (adequacy and validity of consent) as well as patient factors (comprehension and retention) using consent forms and structured interview proformas. The two groups were matched for ASA (American Society of Anesthesiologists) grade and AMTS. The consent forms were adequate in both groups but scored poorly for validity in the NOF group. Only 26% of NOF patients remembered correctly what surgery they had while only 48% recalled the risks and benefits of the procedure. These results were significantly poorer than in THR patients (p = 0.0001). This study confirms that NOF patients are poor at remembering the information conveyed to them at the time of consent when compared with THR patients despite being intellectually and physiologically matched. We suggest using preprinted consent forms (process factors), information sheets and visual aids (patient factors) to improve retention and recall.

  14. Controllable mineral coatings on PCL scaffolds as carriers for growth factor release

    PubMed Central

    Suárez-González, Darilis; Barnhart, Kara; Migneco, Francesco; Flanagan, Colleen; Hollister, Scott J.; Murphy, William L.

    2011-01-01

    In this study, we have developed mineral coatings on polycaprolactone scaffolds to serve as templates for growth factor binding and release. Mineral coatings were formed using a biomimetic approach that consisted in the incubation of scaffolds in modified simulated body fluids (mSBF). To modulate the properties of the mineral coating, which we hypothesized would dictate growth factor release, we used carbonate (HCO3) concentration in mSBF of 4.2 mM, 25mM, and 100mM. Analysis of the mineral coatings formed using scanning electron microscopy indicated growth of a continuous layer of mineral with different morphologies. X-ray diffraction analysis showed peaks associated with hydroxyapatite, the major inorganic constituent of human bone tissue in coatings formed in all HCO3 concentrations. Mineral coatings with increased HCO3 substitution showed more rapid dissolution kinetics in an environment deficient in calcium and phosphate but showed re-precipitation in an environment with the aforementioned ions. The mineral coating provided an effective mechanism for growth factor binding and release. Peptide versions of vascular endothelial growth factor (VEGF) and bone morphogenetic protein 2 (BMP2) were bound with efficiencies up to 90% to mineral mineral-coated PCL scaffolds. We also demonstrated sustained release of all growth factors with release kinetics that were strongly dependent in the solubility of the mineral coating. PMID:22014948

  15. High-throughput spectrometer designs in a compact form-factor: principles and applications

    NASA Astrophysics Data System (ADS)

    Norton, S. M.

    2013-05-01

    Many compact, portable Raman spectrometers have entered the market in the past few years with applications in narcotics and hazardous material identification, as well as verification applications in pharmaceuticals and security screening. Often, the required compact form-factor has forced designers to sacrifice throughput and sensitivity for portability and low-cost. We will show that a volume phase holographic (VPH)-based spectrometer design can achieve superior throughput and thus sensitivity over conventional Czerny-Turner reflective designs. We will look in depth at the factors influencing throughput and sensitivity and illustrate specific VPH-based spectrometer examples that highlight these design principles.

  16. STUDY OF THE INELASTIC SCATTERING OF ELECTRONS BY THE NUCLEI $sup 6$Li AND $sup 7$Li (in French)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bernheim, M.; Bishop, G.R.

    1963-11-01

    We have measured the form factors for transitions to the following excited states by the inelastic scattering of electrons: 2.189, 3.57, and 4.52 Mev of /sup 6/Li; and 0.478, 4.61, 5.76, and 6.8 Mev of /sup 7/Li. The dependence of the form factors on the momentum transfer indicates the principal components of the wave functions describing these states. (auth)

  17. Stackable Form-Factor Peripheral Component Interconnect Device and Assembly

    NASA Technical Reports Server (NTRS)

    Somervill, Kevin M. (Inventor); Ng, Tak-kwong (Inventor); Torres-Pomales, Wilfredo (Inventor); Malekpour, Mahyar R. (Inventor)

    2013-01-01

    A stackable form-factor Peripheral Component Interconnect (PCI) device can be configured as a host controller or a master/target for use on a PCI assembly. PCI device may comprise a multiple-input switch coupled to a PCI bus, a multiplexor coupled to the switch, and a reconfigurable device coupled to one of the switch and multiplexor. The PCI device is configured to support functionality from power-up, and either control function or add-in card function.

  18. Assessment of Physical Self-Concept in Adolescents with Intellectual Disability: Content and Factor Validity of the Very Short Form of the Physical Self-Inventory

    ERIC Educational Resources Information Center

    Maiano, Christophe; Begarie, Jerome; Morin, Alexandre J. S.; Ninot, Gregory

    2009-01-01

    The purpose of this study was to test the factor validity and reliability of the Very Short Form of the Physical Self-Inventory- (PSI-VSF) within a sample of adolescents with mild to moderate Intellectual Disability (ID). A total of 362 ID adolescents were involved in two studies. In Study 1, the content and format scale response of the PSI-VSF…

  19. Upper limits of the proton magnetic form factor in the time-like region from p¯p--> e+e- at the CERN-ISR

    NASA Astrophysics Data System (ADS)

    Baglin, C.; Baird, S.; Bassompierre, G.; Borreani, G.; Brient, J. C.; Broll, C.; Brom, J. M.; Bugge, L.; Buran, T.; Burq, J. P.; Bussière, A.; Buzzo, A.; Cester, R.; Chemarin, M.; Chevallier, M.; Escoubes, B.; Fay, J.; Ferroni, S.; Gracco, V.; Guillaud, J. P.; Khan-Aronsen, E.; Kirsebom, K.; Ille, B.; Lambert, M.; Leistam, L.; Lundby, A.; Macri, M.; Marchetto, F.; Mattera, L.; Menichetti, E.; Mouellic, B.; Pastrone, N.; Petrillo, L.; Pia, M. G.; Poulet, M.; Pozzo, A.; Rinaudo, G.; Santroni, A.; Severi, M.; Skjevling, G.; Stapnes, S.; Stugu, B.; Tomasini, F.; Valbusa, U.

    1985-11-01

    From the measurement of e+e- pairs from the reaction p¯p-->e+e- at the CERN-ISR, using an antiproton beam and a hydrogen jet target, we derived upper limits for the proton magnetic form factor in the time-like region at Q2⋍8.9(GeV/c)2 and Q2⋍12.5(GeV/c)2.

  20. Results from the SAMPLE Experiment

    NASA Astrophysics Data System (ADS)

    Pitt, Mark L.

    1997-10-01

    The neutral weak current can be used to determine the contribution of strange quark-antiquark pairs to the nucleon form factors (D. Kaplan and A. Manohar, Nucl. Phys. B310), 527 (1988).. The SAMPLE experiment measures the neutral weak magnetic form factor of the proton using parity-violating electron scattering, thus providing information on the strange quark sea contribution to the magnetic moment of the proton. The experiment is being performed at the MIT-Bates Linear Accelerator Center. We have recently

  1. Measurement of the B0 -> pilnu form-factor shape and branching fraction, and determination of |Vub| with a loose neutrino reconstruction technique; Mesure du rapport d'embranchement et du facteur deforme de la desintegration B0 to pilnu, et determination de |Vub| avec unetechnique de reconstruction relachee du neutrino (in French)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cote, David

    2007-04-01

    The authors report the results of a study of the exclusive charmless semileptonic decay, B 0 → π -ℓ +v, undertaken with approximately 227 million Bmore » $$\\bar{B}$$ pairs collected at the Y(4S) resonance with the BABAR detector. The analysis uses events in which the signal B decays are reconstructed with an innovative loose neutrino reconstruction technique. They obtain partial branching fractions in 12 bins of q 2, the momentum transfer squared, from which they extract the f +(q 2) form-factor shape and the total branching fraction β(B 0 → π -ℓ +v) = (1.46 ± 0.07 stat ± 0.08 syst) x 10 -4. Based on a recent unquenched lattice QCD calculation of the form factor in the range q 2 > 16 GeV 2/c 4, they find the magnitude of the CKM matrix element |V ub| to be (4.1 ± 0.2 stat ± 0.2 syst$$+0.6\\atop{-0.4}$$FF}) x 10 -3, where the last uncertainty is due to the normalization of the form factor.« less

  2. Abrogation of both short and long forms of latent transforming growth factor-β binding protein-1 causes defective cardiovascular development and is perinatally lethal.

    PubMed

    Horiguchi, Masahito; Todorovic, Vesna; Hadjiolova, Krassimira; Weiskirchen, Ralf; Rifkin, Daniel B

    2015-04-01

    Latent transforming growth factor-β binding protein-1 (LTBP-1) is an extracellular protein that is structurally similar to fibrillin and has an important role in controlling transforming growth factor-β (TGF-β) signaling by storing the cytokine in the extracellular matrix and by being involved in the conversion of the latent growth factor to its active form. LTBP-1 is found as both short (LTBP-1S) and long (LTBP-1L) forms, which are derived through the use of separate promoters. There is controversy regarding the importance of LTBP-1L, as Ltbp1L knockout mice showed multiple cardiovascular defects but the complete null mice did not. Here, we describe a third line of Ltbp1 knockout mice generated utilizing a conditional knockout strategy that ablated expression of both L and S forms of LTBP-1. These mice show severe developmental cardiovascular abnormalities and die perinatally; thus these animals display a phenotype similar to previously reported Ltbp1L knockout mice. We reinvestigated the other "complete" knockout line and found that these mice express a splice variant of LTBP-1L and, therefore, are not complete Ltbp1 knockouts. Our results clarify the phenotypes of Ltbp1 null mice and re-emphasize the importance of LTBP-1 in vivo. Copyright © 2015. Published by Elsevier B.V.

  3. Correlation of transforming growth factor-β1 and tumour necrosis factor levels with left ventricular function in Chagas disease.

    PubMed

    Curvo, Eduardo Ov; Ferreira, Roberto R; Madeira, Fabiana S; Alves, Gabriel F; Chambela, Mayara C; Mendes, Veronica G; Sangenis, Luiz Henrique C; Waghabi, Mariana C; Saraiva, Roberto M

    2018-02-19

    Transforming growth factor β1 (TGF-β1) and tumour necrosis factor (TNF) have been implicated in Chagas disease pathophysiology and may correlate with left ventricular (LV) function. We determined whether TGF-β1 and TNF serum levels correlate with LV systolic and diastolic functions and brain natriuretic peptide (BNP) serum levels in chronic Chagas disease. This cross-sectional study included 152 patients with Chagas disease (43% men; 57 ± 12 years old), classified as 53 patients with indeterminate form and 99 patients with cardiac form (stage A: 24, stage B: 25, stage C: 44, stage D: 6). TGF-β1, TNF, and BNP were determined by enzyme-linked immunosorbent assay ELISA. Echocardiogram was used to determine left atrial and LV diameters, as well as LV ejection fraction and diastolic function. TGF-b1 serum levels were lower in stages B, C, and D, while TNF serum levels were higher in stages C and D of the cardiac form. TGF-β1 presented a weak correlation with LV diastolic function and LV ejection fraction. TNF presented a weak correlation with left atrial and LV diameters and LV ejection fraction. TNF is increased, while TGF-β1 is decreased in the cardiac form of chronic Chagas disease. TNF and TGF-β1 serum levels present a weak correlation with LV systolic and diastolic function in Chagas disease patients.

  4. Electric Form Factor of the Neutron

    NASA Astrophysics Data System (ADS)

    Feuerbach, Robert

    2007-10-01

    Recent polarization-based precision measurements of the nucleons' elastic electric form factors have led to surprising results. The measurement of the ratio of the proton's electromagnetic form factors, μpGE^p/GM^p, was found to drop nearly linearly with Q^2 out to at least 5 GeV^2, inconsistent with the older Rosenbluth-type experiments. A recent measurement of GE^n, the neutron's electric form-factor saw GE^n does not fall off as quickly as commonly expected up to Q^2 1.5 GeV^2. Extending this study, a precision measurement of GE^n up to Q^2=3.5 GeV^2 was completed in Hall A at Jefferson Lab. The ratio GE^n/GM^n was measured through the beam-target asymmetry A of electrons quasi-elastically scattered off polarized neutrons in the reaction ^3He(e,e' n). The experiment took full advantage of the electron beam, recent target developments, as well as two detectors new to Jefferson Lab. The measurement used the accelerator's 100% duty-cycle high-polarization (typically 84%) electron beam and a new, hybrid optically-pumped polarized ^3He target which achieved in-beam polarizations in excess of 50%. A medium acceptance (80msr) open-geometry magnetic spectrometer (BigBite) detected the scattered electron, while a geometrically matched neutron detector observed the struck neutron. Preliminary results from this measurement will be discussed and compared to modern calculations of GE^n.

  5. Polymorph selection: the role of nucleation, crystal growth and molecular modeling.

    PubMed

    Erdemir, Deniz; Lee, Alfred Y; Myerson, Allan S

    2007-11-01

    Solution crystallization is an important separation and purification process used in the chemical, pharmaceutical and food industries. The quality of a crystalline product is generally judged by four main criteria: purity, crystal habit, particle size and solid form. Consistent production of the desired polymorph is crucial as the unanticipated emergence of a different crystal form may have severe consequences. Thus, the selection of a solid-state form for a crystalline product is vital and is ultimately based on knowledge of the properties of the other polymorphs. This review discusses the role of nucleation, crystal growth and molecular modeling on polymorphism in molecular crystals. Examples are presented demonstrating how the first two factors can govern the appearance of a particular crystalline form, and how the latter factor can be used as a tool for understanding polymorphism.

  6. Measurement of the proton form factor ratio at low momentum transfer

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Friedman, Moshe

    Experiment E08-007-II measured the proton elastic form factor ratio μG E=G M in the momentum transfer range of Q 2 ~ 0.02 - 0.08 GeV 2, the lowest ever measured by polarization transfer techniques. The experiment was performed at the Thomas Jefferson National Accelerator Facility in Newport News, Virginia, USA during 2012. A polarized electron beam with energies of 1.1, 1.7, and 2.2 GeV was elastically scattered off a polarized solid NH 3 target. The asymmetries between the cross section of positive and negative helicity states of the beam were determined. These asymmetries can be used to determine the formmore » factor ratio. In this thesis, we present the asymmetry analysis of the experiment, discuss the main challenges and show preliminary results for part of the data. Preliminary asymmetries indicate an increase in the form factor ratio above unity. However, a complete analysis is required before any conclusion can be made. Further analysis is ongoing, and final asymmetry results and form factor extraction is expected during 2017. We also present first results for 14N asymmetries for elastic and quasi-elastic scattering. The measured asymmetries are in agreement with the shell model approximation, within the low accuracy of the measurement. A change in the asymmetry sign between the elastic and the quasi-elastic processes is seen, and should motivate further theoretical studies. These experimental asymmetries will also be useful for systematic studies of other experiments using polarized NH 3 targets.« less

  7. Studies of L-T Separated Kaon Electroproduction

    NASA Astrophysics Data System (ADS)

    Trotta, Richard; Horn, Tanja; Vargas, Andres

    2017-09-01

    QCD is characterized by two emergent phenomena: confinement and dynamical chiral symmetry breaking (DCSB). Pion and kaon form factors are of particular interest as they are connected to the Goldstone modes of DCSB. The flavor degrees of freedom of the produced meson selectively probe aspects of the reaction mechanism and the transition from hadronic to partonic degrees of freedom. There has been significant progress in the theoretical description of the nucleon structure in terms of QCD degrees of freedom, in particular through Generalized Parton Distributions (GPDs).The last decade saw a dramatic improvement in precision of charged pion form factor data and new results have become available on the pion transition form factor. The kaon provides an interesting way to expand these studies, opening the possibility to access the production mechanism involving strangeness. Kaon data at larger virtual photon mass allow one to search for the onset of the partonic picture. In this regime, hard and soft physics have been shown to factorize and GPDs provide the most complete description of the non-perturbative physics. The lack of necessary experimental facilities has left a gap in L-T separated data for exclusive K + production from the proton above the resonance region.The newly upgraded 12 GeV beam energy at Jlab, in addition to the recently built SHMS spectrometer for Hall C, has provided an opportunity to expand the kaon data. Recent kaon form factor and cross section results will be discussed showing the impact of E12-09-011, the running Jlab 12 GeV kaon experiment. NSF Grants PHY1306227, PHY1306418 and PHY1530874.

  8. The Children's Interaction Matrix: Intermediate Form, Primary Form. Preliminary Manual. Research Edition 1975.

    ERIC Educational Resources Information Center

    Drummond, Robert J.; And Others

    The Children's Interaction Matrix, Intermediate and Primary Forms, are designed to identify the preferred work and content styles of children in group situations. These factors aid the researcher, teacher, and counselor in understanding the individual's preferred mode of behavior in groups as well as indicating the students' reaction to group…

  9. An Evaluation of the Factor Structure of the HRM Survey, Forms 9 and 11

    DTIC Science & Technology

    1976-07-01

    Equal Opportunity Index, Social Problems and Processes Equal ...5 2 Equal 64-67 (Form 9) Opportunity 65-68,70 (Form 11) Equal Opportunity, Social Problems and Processes Equal Opportunity, Social ... Social Problems Equal Opportunity Index, Social Problems Drug Abuse Index, Social Problems Alcholism Prevention Index, Social Problems

  10. Initial validation of the Spanish childhood trauma questionnaire-short form: factor structure, reliability and association with parenting.

    PubMed

    Hernandez, Ana; Gallardo-Pujol, David; Pereda, Noemí; Arntz, Arnoud; Bernstein, David P; Gaviria, Ana M; Labad, Antonio; Valero, Joaquín; Gutiérrez-Zotes, Jose Alfonso

    2013-05-01

    The present study examines the internal consistency and factor structure of the Spanish version of the Childhood Trauma Questionnaire-Short Form (CTQ-SF) and the association between the CTQ-SF subscales and parenting style. Cronbach's α and confirmatory factor analyses (CFA) were performed in a female clinical sample (n = 185). Kendall's ι correlations were calculated between the maltreatment and parenting scales in a subsample of 109 patients. The Spanish CTQ-SF showed adequate psychometric properties and a good fit of the 5-factor structure. The neglect and abuse scales were negatively associated with parental care and positively associated with overprotection scales. The results of this study provide initial support for the reliability and validity of the Spanish CTQ-SF.

  11. DSN human factors project

    NASA Technical Reports Server (NTRS)

    Chafin, R. L.; Martin, T. H.

    1980-01-01

    The project plan was to hold focus groups to identify the factors influencing the ease of use characteristics of software and to bond the problem. A questionnaire survey was conducted to evaluate those factors which were more appropriately measured with that method. The performance oriented factors were analyzed and relationships hypothesized. The hypotheses were put to test in the experimental phase of the project. In summary, the initial analysis indicates that there is an initial performance effect favoring computer controlled dialogue but the advantage fades fast as operators become experienced. The user documentation style is seen to have a significant effect on performance. The menu and prompt command formats are preferred by inexperienced operators. The short form mnemonic is least favored. There is no clear best command format but the short form mnemonic is clearly the worst.

  12. 78 FR 69854 - Agency Forms Undergoing Paperwork Reduction Act Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-21

    ... undetermined agents, undetermined sources, undetermined transmission, or undetermined risk factors. These EEIs... transmission, or risk factors to effectively implement rapid prevention and control measures to protect the...; data are analyzed to determine the agents, sources, modes of transmission, or risk factors so that...

  13. Domestic Environmental Risk Factors Associated with Falling in Elderly

    PubMed Central

    LÖK, Neslihan; AKIN, Belgin

    2013-01-01

    Background: This is a cross-sectional study aiming at analyzing the relation between falling and domestic environmental –risk factors in community-dwelling elderly. Methods: The study consisted of 243 randomly chosen community-dwelling elderly over 65 years of age living around a health care center in Central Selcuklu, Konya. Data were collected with a questionnaire form including socio-demographic and other characteristics, with the Rivermead Mobility Index for evaluating mobility condition and an Evaluation Form of Domestic Environmental Risk Factors of Falling (EFDERF), which is developed by the researcher to assess domestic environmental risk factors of falling. Results: Based on (EFDERF) high number of problems lived in bathroom/restroom, kitchen, bedroom, sitting room/saloon and in all other areas was a risk factor in terms of domestic falling characteristics while the number of problems lived in hall and stairs was not a significant risk factor. Conclusion: EFDERF may be used by the nurses and health professionals to evaluate risk of falling and collecting data after visits in primary-care of elderly. PMID:23515204

  14. Exploring sex differences in autistic traits: A factor analytic study of adults with autism.

    PubMed

    Grove, Rachel; Hoekstra, Rosa A; Wierda, Marlies; Begeer, Sander

    2017-08-01

    Research has highlighted potential differences in the phenotypic and clinical presentation of autism spectrum conditions across sex. Furthermore, the measures utilised to evaluate autism spectrum conditions may be biased towards the male autism phenotype. It is important to determine whether these instruments measure the autism phenotype consistently in autistic men and women. This study evaluated the factor structure of the Autism Spectrum Quotient Short Form in a large sample of autistic adults. It also systematically explored specific sex differences at the item level, to determine whether the scale assesses the autism phenotype equivalently across males and females. Factor analyses were conducted among 265 males and 285 females. A two-factor structure consisting of a social behaviour and numbers and patterns factor was consistent across groups, indicating that the latent autism phenotype is similar among both autistic men and women. Subtle differences were observed on two social behaviour item thresholds of the Autism Spectrum Quotient Short Form, with women reporting scores more in line with the scores expected in autism on these items than men. However, these differences were not substantial. This study showed that the Autism Spectrum Quotient Short Form detects autistic traits equivalently in males and females and is not biased towards the male autism phenotype.

  15. Absenteeism amongst health workers--developing a typology to support empiric work in low-income countries and characterizing reported associations.

    PubMed

    Belita, Alice; Mbindyo, Patrick; English, Mike

    2013-07-17

    The contribution of inadequate health worker numbers and emigration have been highlighted in the international literature, but relatively little attention has been paid to absenteeism as a factor that undermines health-care delivery in low income countries. We therefore aimed to review the literature on absenteeism from a health system manager's perspective to inform needed work on this topic. Specifically, we aimed to develop a typology of definitions that might be useful to classify different forms of absenteeism and identify factors associated with absenteeism. Sixty-nine studies were reviewed, only four were from sub-Saharan Africa where the human resources for health crisis is most acute. Forms of absenteeism studied and methods used vary widely. No previous attempt to develop an overarching approach to classifying forms of absenteeism was identified. A typology based on key characteristics is proposed to fill this gap and considers absenteeism as defined by two key attributes, whether it is: planned/unplanned, and voluntary/involuntary. Factors reported to influence rates of absenteeism may be broadly classified into three thematic categories: workplace and content, personal and organizational and cultural factors. The literature presents an inconsistent picture of the effects of specific factors within these themes perhaps related to true contextual differences or inconsistent definitions of absenteeism.

  16. Wechsler Adult Intelligence Scale-Third Edition short form for index and IQ scores in a psychiatric population.

    PubMed

    Christensen, Bruce K; Girard, Todd A; Bagby, R Michael

    2007-06-01

    An eight-subtest short form (SF8) of the Wechsler Adult Intelligence Scale, Third Edition (WAIS-III), maintaining equal representation of each index factor, was developed for use with psychiatric populations. Data were collected from a mixed inpatient/outpatient sample (99 men and 101 women) referred for neuropsychological assessment. Psychometric analyses revealed an optimal SF8 comprising Vocabulary, Similarities, Arithmetic, Digit Span, Picture Completion, Matrix Reasoning, Digit Symbol Coding, and Symbol Search, scored by linear scaling. Expanding on previous short forms, the current SF8 maximizes the breadth of information and reduces administration time while maintaining the original WAIS-III factor structure. (c) 2007 APA, all rights reserved

  17. Knowledge of the physiology of spore-forming bacteria can explain the origin of spores in the food environment.

    PubMed

    Gauvry, Emilie; Mathot, Anne-Gabrielle; Leguérinel, Ivan; Couvert, Olivier; Postollec, Florence; Broussolle, Véronique; Coroller, Louis

    2017-05-01

    Spore-forming bacteria are able to grow under a wide range of environmental conditions, to form biofilms and to differentiate into resistant forms: spores. This resistant form allows their dissemination in the environment; consequently, they may contaminate raw materials. Sporulation can occur all along the food chain, in raw materials, but also in food processes, leading to an increase in food contamination. However, the problem of sporulation during food processing is poorly addressed and sporulation niches are difficult to identify from the farm to the fork. Sporulation is a survival strategy. Some environmental factors are required to trigger this differentiation process and others act by modulating it. The efficiency of sporulation is the result of the combined effects of these two types of factors on vegetative cell metabolism. This paper aims to explain and help identify sporulation niches in the food chain, based on features of spore-former physiology. Copyright © 2016 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.

  18. Factoring vs linear modeling in rate estimation: a simulation study of relative accuracy.

    PubMed

    Maldonado, G; Greenland, S

    1998-07-01

    A common strategy for modeling dose-response in epidemiology is to transform ordered exposures and covariates into sets of dichotomous indicator variables (that is, to factor the variables). Factoring tends to increase estimation variance, but it also tends to decrease bias and thus may increase or decrease total accuracy. We conducted a simulation study to examine the impact of factoring on the accuracy of rate estimation. Factored and unfactored Poisson regression models were fit to follow-up study datasets that were randomly generated from 37,500 population model forms that ranged from subadditive to supramultiplicative. In the situations we examined, factoring sometimes substantially improved accuracy relative to fitting the corresponding unfactored model, sometimes substantially decreased accuracy, and sometimes made little difference. The difference in accuracy between factored and unfactored models depended in a complicated fashion on the difference between the true and fitted model forms, the strength of exposure and covariate effects in the population, and the study size. It may be difficult in practice to predict when factoring is increasing or decreasing accuracy. We recommend, therefore, that the strategy of factoring variables be supplemented with other strategies for modeling dose-response.

  19. Exploratory and Confirmatory Studies of the Structure of the Bem Sex Role Inventory Short Form with Two Divergent Samples

    ERIC Educational Resources Information Center

    Choi, Namok; Fuqua, Dale R.; Newman, Jody L.

    2009-01-01

    The short form of the Bem Sex Role Inventory (BSRI) contains half as many items as the long form and yet has often demonstrated better reliability and validity. This study uses exploratory and confirmatory factor analytic methods to examine the structure of the short form of the BSRI. A structure noted elsewhere also emerged here, consisting of…

  20. Violence against Women

    MedlinePlus

    ... are mostly perpetrated by men against women. Risk factors Factors associated with intimate partner and sexual violence ... These forms of violence can lead to depression, post-traumatic stress and other anxiety disorders, sleep difficulties, ...

  1. Preventive effects of the deleted form of hepatocyte growth factor against various liver injuries.

    PubMed

    Masunaga, H; Fujise, N; Shiota, A; Ogawa, H; Sato, Y; Imai, E; Yasuda, H; Higashio, K

    1998-01-26

    The effects of a naturally occurring deleted form of hepatocyte growth factor (HGF) on hepatic disorder were studied in various models of hepatic failure. The pretreatment of rats and mice with the deleted form of HGF prevented the liver injuries and coagulopathy induced by endotoxin, dimethylnitrosamine and acetaminophen and reduced the mortality due to hepatic dysfunction induced by these hepatotoxins. The concurrent administration of the deleted form of HGF also prevented the liver injury and hepatic fibrosis in mice treated with alpha-naphthylisothiocyanate and in rats treated with dimethylnitrosamine. Moreover, the deleted form of HGF normalized the results of the bromosulphalein-clearance test and ameliorated jaundice in rats with periportal cholangiolitic hepatopathy induced by alpha-naphthylisothiocyanate. The deleted form of HGF also reversed the coagulopathy in rats with hepatic disorder induced by dimethylnitrosamine or by 70% resection of cirrhotic liver (induced by carbon tetrachloride). In Long Evans cinnamon rats receiving vehicle, 20 out of 21 animals died within 4 days after the onset of jaundice. After infusion of the deleted form of HGF for 4 days, 7 out of 20 Long-Evans cinnamon rats survived. These results indicate that the deleted form of HGF could have therapeutic potency in patients with severe hepatic failure.

  2. Nursing students' and preceptors' perceptions of using a revised assessment form in clinical nursing education.

    PubMed

    Löfmark, Anna; Thorell-Ekstrand, Ingrid

    2014-05-01

    Assessment of students' learning is a crucial question when great changes occur in the higher education sector. One such educational reform is the Bologna declaration, the requirements of which have resulted in significant modifications in documents as assessment forms for clinical education. The aim of this study was to investigate students' and preceptors' perceptions of using the revised version of an assessment form, the AssCE form. Using convenience sampling, a questionnaire survey was completed by 192 nursing students and 101 preceptors. Most of the participants found that the revised AssCE form was possible to use during different years of the programme, and factors in the AssCE form were possible to combine with learning outcomes in the course syllabus. Most participants perceived that the scale added to each factor facilitated the assessment dialogue and offered possibilities to illustrate the students' development during clinical periods. Findings also showed that students were most often prepared with self-assessment before the assessment discussions. More information about the use of the AssCE form, also in combination with learning outcomes in the course syllabus, may further support the use of the form and contribute to students' development during clinical practice. Copyright © 2013 Elsevier Ltd. All rights reserved.

  3. Bayesian Factor Analysis When Only a Sample Covariance Matrix Is Available

    ERIC Educational Resources Information Center

    Hayashi, Kentaro; Arav, Marina

    2006-01-01

    In traditional factor analysis, the variance-covariance matrix or the correlation matrix has often been a form of inputting data. In contrast, in Bayesian factor analysis, the entire data set is typically required to compute the posterior estimates, such as Bayes factor loadings and Bayes unique variances. We propose a simple method for computing…

  4. Common Genetic and Nonshared Environmental Factors Contribute to the Association between Socioemotional Dispositions and the Externalizing Factor in Children

    ERIC Educational Resources Information Center

    Taylor, Jeanette; Allan, Nicholas; Mikolajewski, Amy J.; Hart, Sara A.

    2013-01-01

    Background: Childhood behavioral disorders including conduct disorder (CD), oppositional defiant disorder (ODD), and attention-deficit/hyperactivity disorder (ADHD) often co-occur. Prior twin research shows that common sets of genetic and environmental factors are associated with these various disorders and they form a latent factor called…

  5. Modification and Factor Analysis of the Grief Experience Inventory in Non-Death Loss/Bereavement Situations.

    ERIC Educational Resources Information Center

    Zinner, Ellen S.; And Others

    1991-01-01

    Administered Grief Experience Inventory (GEI) to 102 mothers of brain-injured adolescents and young adults across 3 years postinjury. Factor analysis of data was computed and compared to factors derived from original GEI General Reference Group (n=135). Found strikingly similar factor structures between modified nondeath form and original GEI.…

  6. Differentiating the Interests of Mature Women: A Factor Analysis of the KOIS

    ERIC Educational Resources Information Center

    Tittle, Carol Kehr; And Others

    1978-01-01

    Scale scores of KOIS profiles of 202 reentry women were converted to within individual form by means of a z-score transformation. Seven factors emerged on the female-normed scales and 11 factors on the male-normed scales. Four factors were similar in both norm sets and two showed some overlap. (Author)

  7. The Factor Structure of ADHD in a General Population of Primary School Children

    ERIC Educational Resources Information Center

    Ullebo, Anne Karin; Breivik, Kyrre; Gillberg, Christopher; Lundervold, Astri J.; Posserud, Maj-Britt

    2012-01-01

    Objective: To examine whether a bifactor model with a general ADHD factor and domain specific factors of inattention, hyperactivity and impulsivity was supported in a large general population sample of children. We also explored the utility of forming subscales based on the domain-specific factors. Methods: Child mental health questionnaires were…

  8. Excited heavy baryons and their symmetries III: Phenomenology

    NASA Astrophysics Data System (ADS)

    Baccouche, Z. Aziza; Chow, Chi-Keung; Cohen, Thomas D.; Gelman, Boris A.

    2001-12-01

    Phenomenological applications of an effective theory of low-lying excited states of charm and bottom isoscalar baryons are discussed at leading and next-to-leading order in the combined heavy-quark and large- Nc expansion. The combined expansion is formulated in terms of the counting parameter λ˜1/ mQ,1/ Nc; the combined expansion is in powers of λ1/2. We work up to next-to-leading order. We obtain model-independent predictions for the excitation energies, the semileptonic form factors and electromagnetic decay rates. At leading order in the combined expansion these observables are given in terms of one phenomenological constant which can be determined from the excitation energy of the first excited state of Λc baryon. At next-to-leading order an additional phenomenological constant is required. The spin-averaged mass of the doublet of the first orbitally excited state of Λb is predicted to be approximately 5920 MeV. It is shown that in the combined limit at leading and next-to-leading order there is only one independent form factor describing Λ b→Λ cℓ ν¯; similarly, Λ b→Λ c∗ℓ ν¯ and Λ b→Λ c1ℓ ν¯ decays are described by a single independent form factor. These form factors are calculated at leading and next-to-leading order in the combined expansion. The value of the Λ b→Λ cℓ ν¯ form factor at zero recoil is predicted to be 0.998 at leading order which is very close to HQET value of unity. The electromagnetic decay rates of the first excited states of Λc and Λb are determined at leading and next-to-leading order. The ratio of radiative decay rates Γ(Λ c∗→Λ cγ)/Γ(Λ b1→Λ bγ) is predicted to be approximately 0.2, greatly different from the heavy-quark effective theory value of unity.

  9. Proton Form Factor Puzzle and the CEBAF Large Acceptance Spectrometer (CLAS) two-photon exchange experiment

    NASA Astrophysics Data System (ADS)

    Rimal, Dipak

    The electromagnetic form factors are the most fundamental observables that encode information about the internal structure of the nucleon. The electric (GE) and the magnetic ( GM) form factors contain information about the spatial distribution of the charge and magnetization inside the nucleon. A significant discrepancy exists between the Rosenbluth and the polarization transfer measurements of the electromagnetic form factors of the proton. One possible explanation for the discrepancy is the contributions of two-photon exchange (TPE) effects. Theoretical calculations estimating the magnitude of the TPE effect are highly model dependent, and limited experimental evidence for such effects exists. Experimentally, the TPE effect can be measured by comparing the ratio of positron-proton elastic scattering cross section to that of the electron-proton [R = sigma(e +p)/sigma(e+p)]. The ratio R was measured over a wide range of kinematics, utilizing a 5.6 GeV primary electron beam produced by the Continuous Electron Beam Accelerator Facility (CEBAF) at Jefferson Lab. This dissertation explored dependence of R on kinematic variables such as squared four-momentum transfer (Q2) and the virtual photon polarization parameter (epsilon). A mixed electron-positron beam was produced from the primary electron beam in experimental Hall B. The mixed beam was scattered from a liquid hydrogen (LH2) target. Both the scattered lepton and the recoil proton were detected by the CEBAF Large Acceptance Spectrometer (CLAS). The elastic events were then identified by using elastic scattering kinematics. This work extracted the Q2 dependence of R at high epsilon(epsilon > 0.8) and the $epsilon dependence of R at approx 0.85 GeV2. In these kinematics, our data confirm the validity of the hadronic calculations of the TPE effect by Blunden, Melnitchouk, and Tjon. This hadronic TPE effect, with additional corrections contributed by higher excitations of the intermediate state nucleon, largely reconciles the Rosenbluth and the polarization transfer measurements of the electromagnetic form factors.

  10. Teacher Reporting Attitudes Scale (TRAS): confirmatory and exploratory factor analyses with a Malaysian sample.

    PubMed

    Choo, Wan Yuen; Walsh, Kerryann; Chinna, Karuthan; Tey, Nai Peng

    2013-01-01

    The Teacher Reporting Attitude Scale (TRAS) is a newly developed tool to assess teachers' attitudes toward reporting child abuse and neglect. This article reports on an investigation of the factor structure and psychometric properties of the short form Malay version of the TRAS. A self-report cross-sectional survey was conducted with 667 teachers in 14 randomly selected schools in Selangor state, Malaysia. Analyses were conducted in a 3-stage process using both confirmatory (stages 1 and 3) and exploratory factor analyses (stage 2) to test, modify, and confirm the underlying factor structure of the TRAS in a non-Western teacher sample. Confirmatory factor analysis did not support a 3-factor model previously reported in the original TRAS study. Exploratory factor analysis revealed an 8-item, 4-factor structure. Further confirmatory factor analysis demonstrated appropriateness of the 4-factor structure. Reliability estimates for the four factors-commitment, value, concern, and confidence-were moderate. The modified short form TRAS (Malay version) has potential to be used as a simple tool for relatively quick assessment of teachers' attitudes toward reporting child abuse and neglect. Cross-cultural differences in attitudes toward reporting may exist and the transferability of newly developed instruments to other populations should be evaluated.

  11. Confirmatory Factor Analysis of the Behavior Rating Inventory of Executive Function-Adult Version in Healthy Adults and Application to Attention-Deficit/Hyperactivity Disorder

    PubMed Central

    Roth, Robert M.; Lance, Charles E.; Isquith, Peter K.; Fischer, Adina S.; Giancola, Peter R.

    2013-01-01

    The Behavior Rating Inventory of Executive Function-Adult Version (BRIEF-A) is a questionnaire measure designed to assess executive functioning in everyday life. Analysis of data from the BRIEF-A standardization sample yielded a two-factor solution (labeled Behavioral Regulation and Metacognition). The present investigation employed confirmatory factor analysis (CFA) to evaluate four alternative models of the factor structure of the BRIEF-A self-report form in a sample of 524 healthy young adults. Results indicated that a three-factor model best fits the data: a Metacognition factor, a Behavioral Regulation factor consisting of the Inhibit and Self-Monitor scales, and an Emotional Regulation factor composed of the Emotional Control and Shift scales. The three factors contributed 14%, 19%, and 24% of unique variance to the model, respectively, and a second-order general factor accounted for 41% of variance overall. This three-factor solution is consistent with recent CFAs of the Parent report form of the BRIEF. Furthermore, although the Behavioral Regulation factor score in the two-factor model did not differ between adults with attention-deficit/hyperactivity disorder and a matched healthy comparison group, greater impairment on the Behavioral Regulation factor but not the Emotional Regulation factor was found using the three-factor model. Together, these findings support the multidimensional nature of executive function and the clinical relevance of a three-factor model of the BRIEF-A. PMID:23676185

  12. A conserved proline residue in the leucine zipper region of AtbZIP34 and AtbZIP61 in Arabidopsis thaliana interferes with the formation of homodimer.

    PubMed

    Shen, Huaishun; Cao, Kaiming; Wang, Xiping

    2007-10-19

    Two putative Arabidopsis E group bZIP transcript factors, AtbZIP34 and AtbZIP61, are nuclear-localized and their transcriptional activation domain is in their N-terminal region. By searching GenBank, we found other eight plant homologues of AtbZIP34 and AtbZIP61. All of them have a proline residue in the third heptad of zipper region. Yeast two-hybrid assay and EMSA showed that AtbZIP34 and AtbZIP61 could not form homodimer while their mutant forms, AtbZIP34m and AtbZIP61m, which the proline residue was replaced by an alanine residue in the zipper region, could form homodimer and bind G-box element. These results suggest that the conserved proline residue interferes with the homodimer formation. However, both AtbZIP34 and AtbZIP61 could form heterodimers with members of I group and S group transcription factors in which some members involved in vascular development. So we speculate that AtbZIP34 and AtbZIP61 may participate in plant development via interacting with other group bZIP transcription factors.

  13. The nature and evaluation of commercial expert system building tools, revision 1

    NASA Technical Reports Server (NTRS)

    Gevarter, William B.

    1987-01-01

    This memorandum reviews the factors that constitute an Expert System Building Tool (ESBT) and evaluates current tools in terms of these factors. Evaluation of these tools is based on their structure and their alternative forms of knowledge representation, inference mechanisms and developer end-user interfaces. Next, functional capabilities, such as diagnosis and design, are related to alternative forms of mechanization. The characteristics and capabilities of existing commercial tools are then reviewed in terms of these criteria.

  14. Constraints on the H˜ generalized parton distribution from deep virtual Compton scattering measured at HERMES

    NASA Astrophysics Data System (ADS)

    Guidal, M.

    2010-09-01

    We have analyzed the longitudinally polarized proton target asymmetry data of the Deep Virtual Compton process recently published by the HERMES Collaboration in terms of Generalized Parton Distributions. We have fitted these new data in a largely model-independent fashion and the procedure results in numerical constraints on the accent="true">H˜Im Compton Form Factor. We present its t- and ξ-dependencies. We also find improvement on the determination of two other Compton Form Factors, HRe and HIm.

  15. Measurement of the Neutron Electric Form Factor GEN at High Q2

    NASA Astrophysics Data System (ADS)

    McCormick, Kathy

    2003-01-01

    Experiment E02-0131 at Thomas Jefferson National Accelerator Facility (Jefferson Lab) will measure the neutron electric form factor GEn at the high four-momentum transfer values of Q2 ≈ 1.3, 2.4 and 3.4 (GeV/c)2 via a measurement of the cross section asymmetry AT in the reaction {}3vec He(vec e, e'n)pp . This measurement was approved for 32 days of running by Jefferson Lab PAC 212 in January 2002.

  16. Precise measurement of the neutron magnetic form factor G(M)n in the few-GeV2 region.

    PubMed

    Lachniet, J; Afanasev, A; Arenhövel, H; Brooks, W K; Gilfoyle, G P; Higinbotham, D; Jeschonnek, S; Quinn, B; Vineyard, M F; Adams, G; Adhikari, K P; Amaryan, M J; Anghinolfi, M; Asavapibhop, B; Asryan, G; Avakian, H; Bagdasaryan, H; Baillie, N; Ball, J P; Baltzell, N A; Barrow, S; Batourine, V; Battaglieri, M; Beard, K; Bedlinskiy, I; Bektasoglu, M; Bellis, M; Benmouna, N; Berman, B L; Biselli, A S; Bonner, B E; Bookwalter, C; Bouchigny, S; Boiarinov, S; Bradford, R; Branford, D; Briscoe, W J; Bültmann, S; Burkert, V D; Calarco, J R; Careccia, S L; Carman, D S; Casey, L; Cheng, L; Cole, P L; Coleman, A; Collins, P; Cords, D; Corvisiero, P; Crabb, D; Crede, V; Cummings, J P; Dale, D; Daniel, A; Dashyan, N; De Masi, R; De Vita, R; De Sanctis, E; Degtyarenko, P V; Denizli, H; Dennis, L; Deur, A; Dhamija, S; Dharmawardane, K V; Dhuga, K S; Dickson, R; Djalali, C; Dodge, G E; Doughty, D; Dragovitsch, P; Dugger, M; Dytman, S; Dzyubak, O P; Egiyan, H; Egiyan, K S; El Fassi, L; Elouadrhiri, L; Empl, A; Eugenio, P; Fatemi, R; Fedotov, G; Fersch, R; Feuerbach, R J; Forest, T A; Fradi, A; Gabrielyan, M Y; Garçon, M; Gavalian, G; Gevorgyan, N; Giovanetti, K L; Girod, F X; Goetz, J T; Gohn, W; Golovatch, E; Gothe, R W; Graham, L; Griffioen, K A; Guidal, M; Guillo, M; Guler, N; Guo, L; Gyurjyan, V; Hadjidakis, C; Hafidi, K; Hakobyan, H; Hanretty, C; Hardie, J; Hassall, N; Heddle, D; Hersman, F W; Hicks, K; Hleiqawi, I; Holtrop, M; Hu, J; Huertas, M; Hyde-Wright, C E; Ilieva, Y; Ireland, D G; Ishkhanov, B S; Isupov, E L; Ito, M M; Jenkins, D; Jo, H S; Johnstone, J R; Joo, K; Juengst, H G; Kageya, T; Kalantarians, N; Keller, D; Kellie, J D; Khandaker, M; Khetarpal, P; Kim, K Y; Kim, K; Kim, W; Klein, A; Klein, F J; Klusman, M; Konczykowski, P; Kossov, M; Kramer, L H; Kubarovsky, V; Kuhn, J; Kuhn, S E; Kuleshov, S V; Kuznetsov, V; Laget, J M; Langheinrich, J; Lawrence, D; Lima, A C S; Livingston, K; Lowry, M; Lu, H Y; Lukashin, K; Maccormick, M; Malace, S; Manak, J J; Markov, N; Mattione, P; McAleer, S; McCracken, M E; McKinnon, B; McNabb, J W C; Mecking, B A; Mestayer, M D; Meyer, C A; Mibe, T; Mikhailov, K; Mineeva, T; Minehart, R; Mirazita, M; Miskimen, R; Mokeev, V; Moreno, B; Moriya, K; Morrow, S A; Moteabbed, M; Mueller, J; Munevar, E; Mutchler, G S; Nadel-Turonski, P; Nasseripour, R; Niccolai, S; Niculescu, G; Niculescu, I; Niczyporuk, B B; Niroula, M R; Niyazov, R A; Nozar, M; O'Rielly, G V; Osipenko, M; Ostrovidov, A I; Park, K; Park, S; Pasyuk, E; Paterson, C; Pereira, S Anefalos; Philips, S A; Pierce, J; Pivnyuk, N; Pocanic, D; Pogorelko, O; Polli, E; Popa, I; Pozdniakov, S; Preedom, B M; Price, J W; Prok, Y; Protopopescu, D; Qin, L M; Raue, B A; Riccardi, G; Ricco, G; Ripani, M; Ritchie, B G; Rosner, G; Rossi, P; Rowntree, D; Rubin, P D; Sabatié, F; Saini, M S; Salamanca, J; Salgado, C; Sandorfi, A; Santoro, J P; Sapunenko, V; Schott, D; Schumacher, R A; Serov, V S; Sharabian, Y G; Sharov, D; Shaw, J; Shvedunov, N V; Skabelin, A V; Smith, E S; Smith, L C; Sober, D I; Sokhan, D; Starostin, A; Stavinsky, A; Stepanyan, S; Stepanyan, S S; Stokes, B E; Stoler, P; Stopani, K A; Strakovsky, I I; Strauch, S; Suleiman, R; Taiuti, M; Taylor, S; Tedeschi, D J; Thompson, R; Tkabladze, A; Tkachenko, S; Ungaro, M; Vlassov, A V; Watts, D P; Wei, X; Weinstein, L B; Weygand, D P; Williams, M; Wolin, E; Wood, M H; Yegneswaran, A; Yun, J; Yurov, M; Zana, L; Zhang, J; Zhao, B; Zhao, Z W

    2009-05-15

    The neutron elastic magnetic form factor was extracted from quasielastic electron scattering on deuterium over the range Q;{2}=1.0-4.8 GeV2 with the CLAS detector at Jefferson Lab. High precision was achieved with a ratio technique and a simultaneous in situ calibration of the neutron detection efficiency. Neutrons were detected with electromagnetic calorimeters and time-of-flight scintillators at two beam energies. The dipole parametrization gives a good description of the data.

  17. L'etude de l'apprentissage du vocabulaire en contexte par l'ecoute d'un dialogue scenarise en francais langue seconde (The Study of Vocabulary Learning in Context by Listening to a Dialogue in Scenario Form in French as a Second Language).

    ERIC Educational Resources Information Center

    Duquette, Lise

    A study investigated the relative effectiveness of French second language vocabulary learning when presented in two contexts: video, with attention to extralinguistic factors, or audio, with focus on linguistic factors alone. Four student groups (n=137 university students) were formed from existing classes: experimental with video treatment;…

  18. Polarization transfer observables in elastic electron-proton scattering at Q 2 = 2.5 , 5.2, 6.8, and 8.5   GeV 2

    DOE PAGES

    Puckett, Andrew J. R.; Brash, E. J.; Jones, M. K.; ...

    2017-11-06

    In this paper, interest in the behavior of nucleon electromagnetic form factors at large momentum transfers has steadily increased since the discovery, using polarization observables, of the rapid decrease of the ratio G p E/G p M of the proton's electric and magnetic form factors for momentum transfers Q 2 ≳ 1 GeV 2, in strong disagreement with previous extractions of this ratio using the traditional Rosenbluth separation technique.

  19. Polarization transfer observables in elastic electron-proton scattering at Q 2 = 2.5 , 5.2, 6.8, and 8.5   GeV 2

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Puckett, Andrew J. R.; Brash, E. J.; Jones, M. K.

    In this paper, interest in the behavior of nucleon electromagnetic form factors at large momentum transfers has steadily increased since the discovery, using polarization observables, of the rapid decrease of the ratio G p E/G p M of the proton's electric and magnetic form factors for momentum transfers Q 2 ≳ 1 GeV 2, in strong disagreement with previous extractions of this ratio using the traditional Rosenbluth separation technique.

  20. An 8-Item Short Form of the Inventory of Dimensions of Emerging Adulthood (IDEA) Among Young Swiss Men.

    PubMed

    Baggio, Stéphanie; Iglesias, Katia; Studer, Joseph; Gmel, Gerhard

    2015-06-01

    Emerging adulthood is a period of life transition, in which youths are no longer adolescents but have not yet reached full adulthood. Measuring emerging adulthood is crucial because of its association with psychopathology and risky behaviors such as substance use. Unfortunately, the only validated scale for such measurement has a long format (Inventory of Dimensions of Emerging Adulthood [IDEA]-31 items). This study aimed to test whether a shorter form yields satisfactory results without substantial loss of information among a sample of young Swiss men. Data from the longitudinal Cohort Study on Substance Use Risk Factors were used (N = 5,049). IDEA, adulthood markers (e.g., parenthood or financial independence), and risk factors (i.e., substance use and mental health issues) were assessed. The results showed that an 8-item, short-form scale (IDEA-8) with four factors (experimentation, negativity, identity exploration, and feeling in between) returned satisfactory results, including good psychometric properties, high convergence with the initial scale, and strong empirical validity. This study was a step toward downsizing a measure of emerging adulthood. Indeed, this 8-item short form is a good alternative to the 31-item long form and could be more convenient for surveys with constraints on questionnaire length. Moreover, it should help health care practitioners in identifying at-risk populations to prevent and treat risky behaviors. © The Author(s) 2014.

  1. The Built Environment and Active Travel: Evidence from Nanjing, China

    PubMed Central

    Feng, Jianxi

    2016-01-01

    Background: An established relationship exists between the built environment and active travel. Nevertheless, the literature examining the impacts of different components of the built environment is limited. In addition, most existing studies are based on data from cities in the U.S. and Western Europe. The situation in Chinese cities remains largely unknown. Based on data from Nanjing, China, this study explicitly examines the influences of two components of the built environment—the neighborhood form and street form—on residents’ active travel. Methods: Binary logistic regression analyses examined the effects of the neighborhood form and street form on subsistence, maintenance and discretionary travel, respectively. For each travel purpose, three models are explored: a model with only socio-demographics, a model with variables of the neighborhood form and a complete model with all variables. Results: The model fit indicator, Nagelkerke’s ρ2, increased by 0.024 when neighborhood form variables are included and increased by 0.070 when street form variables are taken into account. A similar situation can be found in the models of maintenance activities and discretionary activities. Regarding specific variables, very limited significant impacts of the neighborhood form variables are observed, while almost all of the characteristics of the street form show significant influences on active transport. Conclusions: In Nanjing, street form factors have a more profound influence on active travel than neighborhood form factors. The focal point of the land use regulations and policy of local governments should shift from the neighborhood form to the street form to maximize the effects of policy interventions. PMID:27005645

  2. Effects of disfluencies, predictability, and utterance position on word form variation in English conversation

    NASA Astrophysics Data System (ADS)

    Bell, Alan; Jurafsky, Daniel; Fosler-Lussier, Eric; Girand, Cynthia; Gregory, Michelle; Gildea, Daniel

    2003-02-01

    Function words, especially frequently occurring ones such as (the, that, and, and of ), vary widely in pronunciation. Understanding this variation is essential both for cognitive modeling of lexical production and for computer speech recognition and synthesis. This study investigates which factors affect the forms of function words, especially whether they have a fuller pronunciation (e.g., edh,eye, edh,æ,tee, æ,en,&dee, vee) or a more reduced or lenited pronunciation (e.g., edh,schwa, edh,bari;t, n, schwa). It is based on over 8000 occurrences of the ten most frequent English function words in a 4-h sample from conversations from the Switchboard corpus. Ordinary linear and logistic regression models were used to examine variation in the length of the words, in the form of their vowel (basic, full, or reduced), and whether final obstruents were present or not. For all these measures, after controlling for segmental context, rate of speech, and other important factors, there are strong independent effects that made high-frequency monosyllabic function words more likely to be longer or have a fuller form (1) when neighboring disfluencies (such as filled pauses uh and um) indicate that the speaker was encountering problems in planning the utterance; (2) when the word is unexpected, i.e., less predictable in context; (3) when the word is either utterance initial or utterance final. Looking at the phenomenon in a different way, frequent function words are more likely to be shorter and to have less-full forms in fluent speech, in predictable positions or multiword collocations, and utterance internally. Also considered are other factors such as sex (women are more likely to use fuller forms, even after controlling for rate of speech, for example), and some of the differences among the ten function words in their response to the factors.

  3. 29 CFR 4041.24 - Notices of plan benefits.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... lump sum and the age at which, or form in which, the plan benefits will be paid differs from the normal retirement benefit— (i) The age or form stated in the plan; and (ii) The age or form adjustment factors; and... for the third month before the month in which the lump sum is distributed), a reference to the...

  4. Factor Structure of the BASC-2 Behavioral and Emotional Screening System Student Form

    ERIC Educational Resources Information Center

    Dowdy, Erin; Twyford, Jennifer M.; Chin, Jenna K.; DiStefano, Christine A.; Kamphaus, Randy W.; Mays, Kristen L.

    2011-01-01

    The BASC-2 Behavioral and Emotional Screening System (BESS) Student Form (Kamphaus & Reynolds, 2007) is a recently developed youth self-report rating scale designed to identify students at risk for behavioral and emotional problems. The BESS Student Form was derived from the Behavior Assessment System for Children-Second Edition Self-Report of…

  5. Handwritten Newspapers on the Iowa Frontier, 1844-54.

    ERIC Educational Resources Information Center

    Atwood, Roy Alden

    Journalism on the agricultural frontier of the Old Northwest territory of the United States was shaped by a variety of cultural forces and environmental factors and took on diverse forms. Bridging the gap between the two cultural forms of written correspondence and printed news was a third form: the handwritten newspaper. Between 1844 and 1854…

  6. Shared Risk Factors for the Perpetration of Physical Dating Violence, Bullying, and Sexual Harassment Among Adolescents Exposed to Domestic Violence.

    PubMed

    Foshee, Vangie A; McNaughton Reyes, H Luz; Chen, May S; Ennett, Susan T; Basile, Kathleen C; DeGue, Sarah; Vivolo-Kantor, Alana M; Moracco, Kathryn E; Bowling, J Michael

    2016-04-01

    The high risk of perpetrating physical dating violence, bullying, and sexual harassment by adolescents exposed to domestic violence points to the need for programs to prevent these types of aggression among this group. This study of adolescents exposed to domestic violence examined whether these forms of aggression share risk factors that could be targeted for change in single programs designed to prevent all three types of aggression. Analyses were conducted on 399 mother victims of domestic violence and their adolescents, recruited through community advertising. The adolescents ranged in age from 12 to 16 years; 64 % were female. Generalized estimating equations was used to control for the covariation among the aggression types when testing for shared risk factors. Approximately 70 % of the adolescents reported perpetrating at least one of the three forms of aggression. In models examining one risk factor at a time, but controlling for demographics, adolescent acceptance of sexual violence, mother-adolescent discord, family conflict, low maternal monitoring, low mother-adolescent closeness, low family cohesion, depressed affect, feelings of anger, and anger reactivity were shared across all three aggression types. In multivariable models, which included all of the risk factors examined and the demographic variables, low maternal monitoring, depressed affect and anger reactivity remained significant shared risk factors. Our findings suggest that programs targeting these risk factors for change have the potential to prevent all three forms of aggression. In multivariable models, poor conflict management skills was a risk for bullying and sexual harassment, but not dating violence; acceptance of dating violence was a risk for dating violence and bullying, but not sexual harassment; and none of the examined risk factors were unique to aggression type. The study's implications for the development of interventions and future research are discussed.

  7. Ritualistic child sexual abuse in post-conflict Eastern DRC: Factors associated with the phenomenon and implications for social work.

    PubMed

    Kasherwa, Amani Clovis; Twikirize, Janestic Mwende

    2018-04-30

    Ritualistic child sexual abuse (RCSA) is a critical and under-recognised form of child maltreatment prevailing in developing countries. In the Democratic Republic of Congo (DRC), children from specific communities suffer complex forms of RCSA perpetrated with extreme brutality by various individuals and groups of conspirators. Although the DRC has achieved significant milestones towards combatting war-related sexual abuse of women and children, disturbing forms of RCSA, notably child kidnapping, rape, child defilement for fetish and superstitious beliefs, child sexual exploitation, and cult-based child marriage persist and affect many victims. This study examines the factors associated with the resurgence of RCSA in post-conflict eastern DRC. The article also discusses the implications of such forms of abuse for social work practice and education in a post-war context. Copyright © 2018 Elsevier Ltd. All rights reserved.

  8. Coherent radiation characteristics of modulated electron bunch formed in stack of two plates

    NASA Astrophysics Data System (ADS)

    Gevorgyan, H. L.; Gevorgian, L. A.

    2017-07-01

    The present article is devoted to the radiation from the electron bunch with modulated density passes through the stack consisting of two plates with different thicknesses and electrodynamic properties. The new elegant expression for the frequency-angular distribution of transition radiation is obtained. Using the existence of resonant frequency at which the longitudinal form-factor of bunch not suppresses radiation coherence and choosing parameters for the stack of plates, one can also avoid suppression of the radiation coherence by transverse form-factor of bunch. The radiation from a bunch with modulated density in the process SASE (self-amplified spontaneous emission) FEL can be partially coherent at a resonant frequency. Then the intense sub monochromatic beam of X-ray photons is formed. On the other hand one can define an important parameter of the bunch density modulation depth which is unknown to this day.

  9. Refined structures of three crystal forms of toxic shock syndrome toxin-1 and of a tetramutant with reduced activity.

    PubMed Central

    Prasad, G. S.; Radhakrishnan, R.; Mitchell, D. T.; Earhart, C. A.; Dinges, M. M.; Cook, W. J.; Schlievert, P. M.; Ohlendorf, D. H.

    1997-01-01

    The structure of toxic shock syndrome toxin-1 (TSST-1), the causative agent in toxic shock syndrome, has been determined in three crystal forms. The three structural models have been refined to R-factors of 0.154, 0.150, and 0.198 at resolutions of 2.05 A, 2.90 A, and 2.75 A, respectively. One crystal form of TSST-1 contains a zinc ion bound between two symmetry-related molecules. Although not required for biological activity, zinc dramatically potentiates the mitogenicity of TSST-1 at very low concentrations. In addition, the structure of the tetramutant TSST-1H [T69I, Y80W, E132K, I140T], which is nonmitogenic and does not amplify endotoxin shock, has been determined and refined in a fourth crystal form (R-factor = 0.173 to 1.9 A resolution). PMID:9194182

  10. Dmc1 catalyzes interhomolog joint molecule formation in meiosis with Rad51 and Mei5-Sae3 as accessory factors

    PubMed Central

    Cloud, Veronica; Chan, Yuen-Ling; Grubb, Jennifer; Budke, Brian; Bishop, Douglas K.

    2014-01-01

    Meiotic recombination in budding yeast requires two RecA-related proteins, Rad51 and Dmc1, both of which form filaments on DNA capable of directing homology search and catalyzing formation of homologous joint molecules (JMs) and strand exchange. Using a separation-of-function mutant form of Rad51, that retains filament-forming but not JM forming activity, we show that the JM activity of Rad51 is fully dispensable for meiotic recombination. The corresponding mutation in Dmc1 causes a profound recombination defect, demonstrating Dmc1’s JM activity alone is responsible for meiotic recombination. We further provide biochemical evidence that Rad51 acts with Mei5-Sae3 as a Dmc1 accessory factor. Thus, Rad51 is a multifunctional protein that catalyzes recombination directly in mitosis and indirectly, via Dmc1, during meiosis. PMID:22955832

  11. Rad51 is an accessory factor for Dmc1-mediated joint molecule formation during meiosis.

    PubMed

    Cloud, Veronica; Chan, Yuen-Ling; Grubb, Jennifer; Budke, Brian; Bishop, Douglas K

    2012-09-07

    Meiotic recombination in budding yeast requires two RecA-related proteins, Rad51 and Dmc1, both of which form filaments on DNA capable of directing homology search and catalyzing formation of homologous joint molecules (JMs) and strand exchange. With use of a separation-of-function mutant form of Rad51 that retains filament-forming but not JM-forming activity, we show that the JM activity of Rad51 is fully dispensable for meiotic recombination. The corresponding mutation in Dmc1 causes a profound recombination defect, demonstrating Dmc1's JM activity alone is responsible for meiotic recombination. We further provide biochemical evidence that Rad51 acts with Mei5-Sae3 as a Dmc1 accessory factor. Thus, Rad51 is a multifunctional protein that catalyzes recombination directly in mitosis and indirectly, via Dmc1, during meiosis.

  12. 77 FR 76044 - Agency Forms Undergoing Paperwork Reduction Act Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-26

    ... delivery of services for women who have limited access to health care and elevated risk factors for cardiovascular disease (CVD). The program focuses on reducing CVD risk factors and provides screening services for select risk factors such as elevated blood cholesterol, hypertension and abnormal blood glucose...

  13. 77 FR 40363 - Agency Forms Undergoing Paperwork Reduction Act Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-09

    ... comments should be received within 30 days of this notice. Proposed Project Risk Factors for Invasive...-associated invasive MRSA infections are to quantify the burden and to identify modifiable risk factors... discharged from an acute care hospital in the prior 3 months. Risk factors for invasive MRSA infections post...

  14. 76 FR 70728 - Agency Forms Undergoing Paperwork Reduction Act Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-15

    ... stock in the United States and potentially modifiable risk factors. The objectives for developing this... housing-related risk factors. Childhood lead poisoning is just one of many adverse health conditions that...

  15. Endothelial cell colony forming units derived from malignant breast diseases are resistant to tumor necrosis factor-α-induced apoptosis.

    PubMed

    Chou, Chen-Pin; Jiang, Shih Sheng; Pan, Huay-Ben; Yen, Yi-Chen; Tseng, Hui-Hwa; Hung, Yu-Ting; Wang, Ssu-Han; Chen, Yu-Lin; Chen, Ya-Wen

    2016-11-24

    Mobilisation of endothelial progenitor cells (EPCs) from the bone marrow is a crucial step in the formation of de novo blood vessels, and levels of peripheral blood EPCs have been shown to be elevated in certain malignant states. Using flow cytometry and a Hill-based colony forming unit (CFU) assay, the present study indicated that higher levels of CD34 and vascular endothelial growth factor receptor 2 (VEGFR2) double-positive EPCs, as well as increased formation of endothelial cell colony-forming units (EC-CFUs) are associated with benign and malignant breast diseases, providing possible indicators for breast disease detection. Gene expression profiles revealed a genetic difference between CD34 + VEGFR2 + EPCs and EC-CFUs. Decreased expression of tumour necrosis factor receptor 2 (TNFR2) signalling-related genes and inhibition of tumour necrosis factor (TNF)-induced signalling were demonstrated in EC-CFUs derived from patients with malignant breast disease in comparison with those from healthy controls. Interestingly, our data provided the first evidence that EC-CFUs derived from patients with malignant breast disease were resistant to TNF-α-induced apoptosis, indicating a plausible target for future therapeutic interventions.

  16. Age-Related Macular Degeneration: New Paradigms for Treatment and Management of AMD.

    PubMed

    Hernández-Zimbrón, Luis Fernando; Zamora-Alvarado, Ruben; Ochoa-De la Paz, Lenin; Velez-Montoya, Raul; Zenteno, Edgar; Gulias-Cañizo, Rosario; Quiroz-Mercado, Hugo; Gonzalez-Salinas, Roberto

    2018-01-01

    Age-related macular degeneration (AMD) is a well-characterized and extensively studied disease. It is currently considered the leading cause of visual disability among patients over 60 years. The hallmark of early AMD is the formation of drusen, pigmentary changes at the macula, and mild to moderate vision loss. There are two forms of AMD: the "dry" and the "wet" form that is less frequent but is responsible for 90% of acute blindness due to AMD. Risk factors have been associated with AMD progression, and they are taking relevance to understand how AMD develops: (1) advanced age and the exposition to environmental factors inducing high levels of oxidative stress damaging the macula and (2) this damage, which causes inflammation inducing a vicious cycle, altogether causing central vision loss. There is neither a cure nor treatment to prevent AMD. However, there are some treatments available for the wet form of AMD. This article will review some molecular and cellular mechanisms associated with the onset of AMD focusing on feasible treatments for each related factor in the development of this pathology such as vascular endothelial growth factor, oxidative stress, failure of the clearance of proteins and organelles, and glial cell dysfunction in AMD.

  17. Constructing a short form of the hierarchical personality inventory for children (HiPIC): the HiPIC-30.

    PubMed

    Vollrath, Margarete E; Hampson, Sarah E; Torgersen, Svenn

    2016-05-01

    Children's personality traits are invaluable predictors of concurrent and later mental and physical health. Several validated longer inventories for assessing the widely recognized Five-Factor Model of personality in children are available, but short forms are scarce. This study aimed at constructing a 30-item form of the 144-item Hierarchical Personality Inventory for Children (HiPIC) (Mervielde & De Fruyt, ). Participants were 1543 children aged 6-12 years (sample 1) and 3895 children aged 8 years (sample 2). Sample 1 completed the full HiPIC, from which we constructed the HiPIC-30, and the Child Behaviour Checklist (Achenbach, ). Sample 2 completed the HiPIC-30. The HiPIC-30 personality domains correlated over r = .90 with the full HiPIC domains, had good Cronbach's alphas and correlated similarly with CBCL behaviour problems and gender as the full HiPIC. The factor structures of the HiPIC-30 were convergent across samples, but the imagination factor was not clear-cut. We conclude that the HiPIC-30 is a reliable and valid questionnaire for the Five-Factor personality traits in children. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  18. An Examination of the Partner Cyber Abuse Questionnaire in a College Student Sample.

    PubMed

    Wolford-Clevenger, Caitlin; Zapor, Heather; Brasfield, Hope; Febres, Jeniimarie; Elmquist, JoAnna; Brem, Meagan; Shorey, Ryan C; Stuart, Gregory L

    2016-01-01

    To examine the factor structure and convergent validity of a newly developed measure of an understudied form of partner abuse, cyber abuse, and to examine the prevalence of, and gender differences in, victimization by cyber abuse. College students in a dating relationship ( N = 502) completed the Partner Cyber Abuse Questionnaire (Hamby, 2013), as well as measures of partner abuse victimization and depression. Using exploratory factor analysis, we determined a one-factor solution was the most statistically and conceptually best fitting model. The cyber abuse victimization factor was correlated with depressive symptoms and physical, psychological, and sexual partner abuse victimization, supporting the convergent validity of the measure. The overall prevalence of victimization by cyber abuse was 40%, with victimization by specific acts ranging from 2-31%. Men and women did not differ in their victimization by cyber abuse. Cyber abuse is prevalent among college students and occurs concurrently with other partner abuse forms and depressive symptoms. Given the interrelated nature of partner abuse forms, prevention and intervention programs should address partner abuse occurring in-person and through technology. Cyber abuse should also be considered in the conceptualization and measurement of partner abuse to more fully understand this social problem.

  19. Reaction μ-+6Li-->3H+3H+νμ and the axial current form factor in the timelike region

    NASA Astrophysics Data System (ADS)

    Mintz, S. L.

    1983-09-01

    The differential muon-capture rate dΓdET is obtained for the reaction μ-+6Li-->3H+3H+νμ over the allowed range of ET, the tritium energy, for two assumptions concerning the behavior of FA, the axial current form factor, in the timelike region; analytic continuation from the spacelike region and mirror behavior, FA(q2, timelike)=FA(q2, spacelike). The values of dΓdET under these two assumptions are found to vary substantially in the timelike region as a function of the mass MA in the dipole fit to FA. Values of dΓdET are given for MA2=2mπ2, 4.95mπ2, and 8mπ2. NUCLEAR REACTIONS Muon capture 6Li(μ-, νμ)3H3H, Γ, dΓdET calculated for two assumptions concerning the axial current form factor behavior in timelike region.

  20. Measurement of the generalized form factors near threshold via γ *p → nπ + at high Q 2

    DOE PAGES

    Park, K.; Adhikari, K. P.; Adikaram, D.; ...

    2012-03-26

    We report the first extraction of the pion-nucleon multipoles near the production threshold for the nπ + channel at relatively high momentum transfer (Q 2 up to 4.2 GeV 2). The dominance of the s-wave transverse multipole (E 0+), expected in this region, allowed us to access the generalized form factor G 1 within the light-cone sum rule (LCSR) framework as well as the axial form factor G A. The data analyzed in this work were collected by the nearly 4π CEBAF Large Acceptance Spectrometer (CLAS) using a 5.754-GeV electron beam on a proton target. The differential cross section andmore » the π-N multipole E 0+/G D were measured using two different methods, the LCSR and a direct multipole fit. The results from the two methods are found to be consistent and almost Q 2 independent.« less

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