Non-verbal Full Body Emotional and Social Interaction: A Case Study on Multimedia Systems for Active Music Listening

NASA Astrophysics Data System (ADS)

Camurri, Antonio

Research on HCI and multimedia systems for art and entertainment based on non-verbal, full-body, emotional and social interaction is the main topic of this paper. A short review of previous research projects in this area at our centre are presented, to introduce the main issues discussed in the paper. In particular, a case study based on novel paradigms of social active music listening is presented. Active music listening experience enables users to dynamically mould expressive performance of music and of audiovisual content. This research is partially supported by the 7FP EU-ICT Project SAME (Sound and Music for Everyone, Everyday, Everywhere, Every Way, www.sameproject.eu).

CHANGES SDSS: the development of a Spatial Decision Support System for analysing changing hydro-meteorological risk

NASA Astrophysics Data System (ADS)

van Westen, Cees; Bakker, Wim; Zhang, Kaixi; Jäger, Stefan; Assmann, Andre; Kass, Steve; Andrejchenko, Vera; Olyazadeh, Roya; Berlin, Julian; Cristal, Irina

2014-05-01

Within the framework of the EU FP7 Marie Curie Project CHANGES (www.changes-itn.eu) and the EU FP7 Copernicus project INCREO (http://www.increo-fp7.eu) a spatial decision support system is under development with the aim to analyse the effect of risk reduction planning alternatives on reducing the risk now and in the future, and support decision makers in selecting the best alternatives. The Spatial Decision Support System will be composed of a number of integrated components. The Risk Assessment component allows to carry out spatial risk analysis, with different degrees of complexity, ranging from simple exposure (overlay of hazard and assets maps) to quantitative analysis (using different hazard types, temporal scenarios and vulnerability curves) resulting into risk curves. The platform does not include a component to calculate hazard maps, and existing hazard maps are used as input data for the risk component. The second component of the SDSS is a risk reduction planning component, which forms the core of the platform. This component includes the definition of risk reduction alternatives (related to disaster response planning, risk reduction measures and spatial planning) and links back to the risk assessment module to calculate the new level of risk if the measure is implemented, and a cost-benefit (or cost-effectiveness/ Spatial Multi Criteria Evaluation) component to compare the alternatives and make decision on the optimal one. The third component of the SDSS is a temporal scenario component, which allows to define future scenarios in terms of climate change, land use change and population change, and the time periods for which these scenarios will be made. The component doesn't generate these scenarios but uses input maps for the effect of the scenarios on the hazard and assets maps. The last component is a communication and visualization component, which can compare scenarios and alternatives, not only in the form of maps, but also in other forms (risk curves, tables, graphs). The envisaged users of the platform are organizations involved in planning of risk reduction measures, and that have staff capable of visualizing and analysing spatial data at a municipal scale.

NBS for Drought risks reduction in the Algarve (Portugal): selected achievements from PT FCT ProWaterMan and from EU FP7 MARSOL projects

NASA Astrophysics Data System (ADS)

Lobo-Ferreira, João-Paulo

2017-04-01

Southern Europe and the Mediterranean region are facing the challenge of managing its water resources under conditions of increasing scarcity and/or floods, besides concerns about water quality. Innovative water management strategies with nature-based solutions, such as the storage of excess water during floods, in Managed Aquifer Recharge (MAR) schemes can greatly decrease the risk of floods while it increases water availability for future use, eventually in drought periods. The Algarve region is the southern most region of Portugal mainland. It has an area of 4,997 km2 and about 451 thousand permanent inhabitants. Selected achievements of two research projects (Portugal FCT sponsored ProWaterMan project and EU FP7 sponsored MARSOL project), will be addressed regarding the Campina de Faro and Querença-Silves aquifers in the Algarve. In Faro, the idea of harvesting rainwater from the greenhouse rooftops and using this water to recharge aquifers is not new. However, using this NbS as a climate mitigation and adaptation tool with the overall impact and wide range of benefits is a step forward in innovative methodologies. This NbS can have particular positive impacts in Mediterranean conditions with (new) precipitation patterns, more intense but less frequent. The potential greenhouses surface area of about 2.74 km2 can be used by connecting these infrastructures to several large wells aiming to infiltrate an amount of 1.63 hm3/year of harvested water. There is a strong support from the Portuguese Water Agency (Agência Portuguesa do Ambiente, I.P., Algarve branch), the Water Supplier and Wastewater (Águas do Algarve, S.A.), and the local farmers and land owners which have frequent flood and/or drought problems, represented by HUBEL (a SME that produces most greenhouses for Faro area) in this project. During EU 7FP INO-DEMO MARSOL project, a survey about protection and preservation of groundwater was conducted with a sample of Portuguese farmers of the Algarve region. It included the evaluation of willingness of farmers to collaborate and pay for the use of Managed Aquifer Recharge (MAR) as a nature-based solution to minimize the drought impacts and to manage flood risk in the area. Close cooperation has been established between EIP Water Action Group MARsolutions and FP7 MARSOL INNO_DEMO (http://www.eip-water.eu/close-cooperation-between-eip-marsolutions-and-fp7-marsol-inno-demo-project ). In http://www.eip-water.eu/sites/default/files/Rel%20101_15.pdf a LNEC report is available, presenting a descriptive analysis of the responses to a survey about protection and preservation of groundwater conducted with a sample of Portuguese farmers of the Algarve region. It is possible that Direção Regional de Agricultura e Pescas do Algarve is willing to participate on the implementation the nature-based solutions as they will decrease the risk for agriculture losses. The Portuguese Water Agency has precipitation and flow bulletins for the Algarve, e.g. for Faro and Albufeira areas, in http://snirh.pt/index.php?idMain=1&idItem=1.1 . Concerning the climate change impact in Querença-Silves (QS) Aquifer, LNEC/University of Algarve MARSOL project teams presented descriptions regarding respectively groundwater recharge and flow simulations of future scenarios. E.g. Stigter et al. (2009, 2014) summarized achieved conclusions were "(1) (2020-2050) changes in recharge, particularly due to a reduction in autumn rainfall resulting in a longer dry period. More frequent droughts are predicted at the QS aquifer; (2) toward the end of the century (2069-2099), results indicate a significant decrease (mean 25 %) in recharge at QS aquifer, with an high decrease in absolute terms (mean 134 mm/year); and, (3) scenario modelling of groundwater flow shows its response to the predicted decreases in recharge and increases in pumping rates, with strongly reduced outflow into the coastal wetlands, whereas changes due to sea level rise are negligible". These results are a useful starting point regarding the role of MAR in aquifer systems, taking into account the future trends of climate change patterns expected in the Mediterranean region.

What Are We Aiming For?--A Delphi Study on the Development of Civic Scientific Literacy in Sweden

ERIC Educational Resources Information Center

Chang Rundgren, Shu-Nu; Rundgren, Carl-Johan

2017-01-01

Based on the EU FP 7 project, PROFILES, this article presents our findings from a three-round Delphi study conducted in Sweden that aimed at establishing a consensus on how science education should be developed for citizens to enhance civic scientific literacy. A total of 100 stakeholders (9th graders, school teachers, scientists, and science…

Comparative development of knowledge-based bioeconomy in the European Union and Turkey.

PubMed

Celikkanat Ozan, Didem; Baran, Yusuf

2014-09-01

Biotechnology, defined as the technological application that uses biological systems and living organisms, or their derivatives, to create or modify diverse products or processes, is widely used for healthcare, agricultural and environmental applications. The continuity in industrial applications of biotechnology enables the rise and development of the bioeconomy concept. Bioeconomy, including all applications of biotechnology, is defined as translation of knowledge received from life sciences into new, sustainable, environment friendly and competitive products. With the advanced research and eco-efficient processes in the scope of bioeconomy, more healthy and sustainable life is promised. Knowledge-based bioeconomy with its economic, social and environmental potential has already been brought to the research agendas of European Union (EU) countries. The aim of this study is to summarize the development of knowledge-based bioeconomy in EU countries and to evaluate Turkey's current situation compared to them. EU-funded biotechnology research projects under FP6 and FP7 and nationally-funded biotechnology projects under The Scientific and Technological Research Council of Turkey (TUBITAK) Academic Research Funding Program Directorate (ARDEB) and Technology and Innovation Funding Programs Directorate (TEYDEB) were examined. In the context of this study, the main research areas and subfields which have been funded, the budget spent and the number of projects funded since 2003 both nationally and EU-wide and the gaps and overlapping topics were analyzed. In consideration of the results, detailed suggestions for Turkey have been proposed. The research results are expected to be used as a roadmap for coordinating the stakeholders of bioeconomy and integrating Turkish Research Areas into European Research Areas.

EU Funded Research Activities on NPPS Operational Safety

DOE Office of Scientific and Technical Information (OSTI.GOV)

Manolatos, P.; Van Goethem, G.

2002-07-01

The 5. framework programme (FP-5), the pluri-annual research programme of the European Union (EU), covers the period 1998-2002. Research on nuclear energy, fusion and fission, is covered by the EURATOM part of the FP-5. An overview of the Euratom's research on Nuclear Reactor Safety, managed by the DG-RTD of the European Commission (EC), is presented. This concerns 70 multi-partner projects of approximately euro 82.5 million total contract value that have been selected and co-financed during the period 1999-2001. They form the three clusters of projects dealing with the 'Operational Safety of Existing Installations'. 'Plant Life Extension and Management' (PLEM), 'Severemore » Accident Management' (SAM) and 'Evolutionary concepts' (EVOL). Emphasis is given here to the projects of the PLEM cluster. (authors)« less

Accelerators for society: succession of European infrastructural projects: CARE, EuCARD, TIARA, EuCARD2

NASA Astrophysics Data System (ADS)

Romaniuk, Ryszard S.

2013-10-01

Accelerator science and technology is one of a key enablers of the developments in the particle physic, photon physics and also applications in medicine and industry. The paper presents a digest of the research results in the domain of accelerator science and technology in Europe, shown during the realization of CARE (Coordinated Accelerator R&D), EuCARD (European Coordination of Accelerator R&D) and during the national annual review meeting of the TIARA - Test Infrastructure of European Research Area in Accelerator R&D. The European projects on accelerator technology started in 2003 with CARE. TIARA is an European Collaboration of Accelerator Technology, which by running research projects, technical, networks and infrastructural has a duty to integrate the research and technical communities and infrastructures in the global scale of Europe. The Collaboration gathers all research centers with large accelerator infrastructures. Other ones, like universities, are affiliated as associate members. TIARA-PP (preparatory phase) is an European infrastructural project run by this Consortium and realized inside EU-FP7. The paper presents a general overview of CARE, EuCARD and especially TIARA activities, with an introduction containing a portrait of contemporary accelerator technology and a digest of its applications in modern society. CARE, EuCARD and TIARA activities integrated the European accelerator community in a very effective way. These projects are expected very much to be continued.

Nanophotonic biosensor for space exploration (PBSA instrument)

NASA Astrophysics Data System (ADS)

Pantoja, S.; Parro, V.; Nestler, J.; Geidel, S.; Martins, R.; Cuesta, F.; Elvira, J. G.; Sousa, A.

2017-11-01

One of the biggest challenges of Astrobiology is the search for clear signs of present or past life on other planetary bodies. Thus, this poster will describe the project "Photonic Biosensor for Space Application" (PBSA, www.pbsa-fp7.eu) founded by the Directorate-General for Enterprise and Industry (DG ENTR) within the European Commission and managed by the Unit S2 (Space Research) of the Research European Agency (REA).

EuCARD 2010: European coordination of accelerator research and development

NASA Astrophysics Data System (ADS)

Romaniuk, Ryszard S.

2010-09-01

Accelerators are basic tools of the experimental physics of elementary particles, nuclear physics, light sources of the fourth generation. They are also used in myriad other applications in research, industry and medicine. For example, there are intensely developed transmutation techniques for nuclear waste from nuclear power and atomic industries. The European Union invests in the development of accelerator infrastructures inside the framework programs to build the European Research Area. The aim is to build new accelerator research infrastructures, develop the existing ones, and generally make the infrastructures more available to competent users. The paper summarizes the first year of activities of the EU FP7 Project Capacities EuCARD -European Coordination of Accelerator R&D. EuCARD is a common venture of 37 European Accelerator Laboratories, Institutes, Universities and Industrial Partners involved in accelerator sciences and technologies. The project, initiated by ESGARD, is an Integrating Activity co-funded by the European Commission under Framework Program 7 - Capacities for a duration of four years, starting April 1st, 2009. Several teams from this country participate actively in this project. The contribution from Polish research teams concerns: photonic and electronic measurement - control systems, RF-gun co-design, thin-film superconducting technology, superconducting transport infrastructures, photon and particle beam measurements and control.

21st Century Climate Change in the European Alps

NASA Astrophysics Data System (ADS)

Gobiet, Andreas; Kotlarski, Sven; Stoffel, Markus; Heinrich, Georg; Rajczak, Jan; Beniston, Martin

2014-05-01

The Alps are particularly sensitive to global warming and warmed twice as much as the global average in the recent past. In addition, the Alps and its surroundings are a densly populated areas where society is affected by climate change in many ways, which calls for reliable estimates of future climate change. However, the complex Alpine region poses considerable challenges to climate models, which translate to uncertainties in future climate projections. Against this background, the present study reviews the state-of-knowledge about 21st century climate change in the Alps based on existing literature and additional analyses. It will be demonstrated that considerable and accelerating changes are not only to be expected with regard to temperature, but also precipitation, global radiation, relative humidity, and closely related impacts like floods, droughts, snow cover, and natural hazards will be effected by global warming. Under the A1B emission scenario, about 0.25 °C warming per decade until the mid of the 21st century and accelerated 0.36 °C warming per decade in the second half of the century is expected. Warming will most probably be associated with changes in the seasonality of precipitation, global radiation, and relative humidity. More intense precipitation extremes and flooding potential are particularly expected in the colder part of the year. The conditions of currently record breaking warm or hot winter or summer seasons, respectively, may become normal at the end of the 21st century, and there is indication for droughts to become more severe in the future. Snow cover is expected to drastically decrease below 1500 - 2000 m and natural hazards related to glacier and permafrost retreat are expected to become more frequent. Such changes in climatic variables and related quantities will have considerable impact on ecosystems and society and will challenge their adaptive capabilities. Acknowledgements: This study has been initiated and is partly funded by the EU FP6 project ACQWA (www.acqwa.ch). Additional funding has been provided by the project ARNICA (http://www.lgp.cnrs-bellevue.fr/arnica/), funded under the EU CIRCLE-2 mountain call, by the Swiss National Science Foundation through the Sinergia project TEMPS, and the Austrian Climate Research Program (ACRP) through the projects reclip:century and DEUCALION. We acknowledge the RCM data sets from the EU- FP6 project ENSEMBLES (http://ensembles-eu.metoffice.com). In particular, we thank Sebastian R. Scher (University of Graz) for the preparation of several figures in this study.This study has been supported by the EU project ACQWA (FP7 no. 212250) and the ACRP project reclip:century 2 (No. A963768).

EU FP7 project 'CAMbrella' to build European research network for complementary and alternative medicine.

PubMed

Weidenhammer, Wolfgang; Lewith, George; Falkenberg, Torkel; Fønnebø, Vinjar; Johannessen, Helle; Reiter, Bettina; Uehleke, Bernhard; von Ammon, Klaus; Baumhöfener, Franziska; Brinkhaus, Benno

2011-01-01

The status of complementary and alternative medicine (CAM) within the EU needs clarification. The definition and terminology of CAM is heterogeneous. The therapies, legal status, regulations and approaches used vary from country to country but there is widespread use by EU citizens. A coordination project funded by the EU has been launched to improve the knowledge about CAM in Europe. The project aims to evaluate the conditions surrounding CAM use and provision in Europe and to develop a roadmap for European CAM research. Specific objectives are to establish an EU network involving centres of research excellence for collaborative projects, to develop consensus-based terminology to describe CAM interventions, to create a knowledge base that facilitates the understanding of patient demand for CAM and its prevalence, to review the current legal status and policies governing CAM provision, and to explore the needs and attitudes of EU citizens with respect to CAM. Based on this information a roadmap will be created that will enable sustainable and prioritised future European research in CAM. CAMbrella encompasses 16 academic research groups from 12 European countries and will run for 36 months starting from January 2010. The project will be delivered in 9 work packages coordinated by a Management Board and directed by a Scientific Steering Committee with support of an Advisory Board. The outcomes generated will be disseminated through the project's website, peer review open access publications and a final conference, with emphasis on current and future EU policies, addressing different target audiences. Copyright © 2011 S. Karger AG, Basel.

European monitoring systems and data for assessing environmental and climate impacts on human infectious diseases.

PubMed

Nichols, Gordon L; Andersson, Yvonne; Lindgren, Elisabet; Devaux, Isabelle; Semenza, Jan C

2014-04-09

Surveillance is critical to understanding the epidemiology and control of infectious diseases. The growing concern over climate and other drivers that may increase infectious disease threats to future generations has stimulated a review of the surveillance systems and environmental data sources that might be used to assess future health impacts from climate change in Europe. We present an overview of organizations, agencies and institutions that are responsible for infectious disease surveillance in Europe. We describe the surveillance systems, tracking tools, communication channels, information exchange and outputs in light of environmental and climatic drivers of infectious diseases. We discuss environmental and climatic data sets that lend themselves to epidemiological analysis. Many of the environmental data sets have a relatively uniform quality across EU Member States because they are based on satellite measurements or EU funded FP6 or FP7 projects with full EU coverage. Case-reporting systems for surveillance of infectious diseases should include clear and consistent case definitions and reporting formats that are geo-located at an appropriate resolution. This will allow linkage to environmental, social and climatic sources that will enable risk assessments, future threat evaluations, outbreak management and interventions to reduce disease burden.

European Monitoring Systems and Data for Assessing Environmental and Climate Impacts on Human Infectious Diseases

PubMed Central

Nichols, Gordon L.; Andersson, Yvonne; Lindgren, Elisabet; Devaux, Isabelle; Semenza, Jan C.

2014-01-01

Surveillance is critical to understanding the epidemiology and control of infectious diseases. The growing concern over climate and other drivers that may increase infectious disease threats to future generations has stimulated a review of the surveillance systems and environmental data sources that might be used to assess future health impacts from climate change in Europe. We present an overview of organizations, agencies and institutions that are responsible for infectious disease surveillance in Europe. We describe the surveillance systems, tracking tools, communication channels, information exchange and outputs in light of environmental and climatic drivers of infectious diseases. We discuss environmental and climatic data sets that lend themselves to epidemiological analysis. Many of the environmental data sets have a relatively uniform quality across EU Member States because they are based on satellite measurements or EU funded FP6 or FP7 projects with full EU coverage. Case-reporting systems for surveillance of infectious diseases should include clear and consistent case definitions and reporting formats that are geo-located at an appropriate resolution. This will allow linkage to environmental, social and climatic sources that will enable risk assessments, future threat evaluations, outbreak management and interventions to reduce disease burden. PMID:24722542

Paving the way of systems biology and precision medicine in allergic diseases: the MeDALL success story: Mechanisms of the Development of ALLergy; EU FP7-CP-IP; Project No: 261357; 2010-2015.

PubMed

Bousquet, J; Anto, J M; Akdis, M; Auffray, C; Keil, T; Momas, I; Postma, D S; Valenta, R; Wickman, M; Cambon-Thomsen, A; Haahtela, T; Lambrecht, B N; Lodrup Carlsen, K C; Koppelman, G H; Sunyer, J; Zuberbier, T; Annesi-Maesano, I; Arno, A; Bindslev-Jensen, C; De Carlo, G; Forastiere, F; Heinrich, J; Kowalski, M L; Maier, D; Melén, E; Palkonen, S; Smit, H A; Standl, M; Wright, J; Asarnoj, A; Benet, M; Ballardini, N; Garcia-Aymerich, J; Gehring, U; Guerra, S; Hohman, C; Kull, I; Lupinek, C; Pinart, M; Skrindo, I; Westman, M; Smagghe, D; Akdis, C; Albang, R; Anastasova, V; Anderson, N; Bachert, C; Ballereau, S; Ballester, F; Basagana, X; Bedbrook, A; Bergstrom, A; von Berg, A; Brunekreef, B; Burte, E; Carlsen, K H; Chatzi, L; Coquet, J M; Curin, M; Demoly, P; Eller, E; Fantini, M P; Gerhard, B; Hammad, H; von Hertzen, L; Hovland, V; Jacquemin, B; Just, J; Keller, T; Kerkhof, M; Kiss, R; Kogevinas, M; Koletzko, S; Lau, S; Lehmann, I; Lemonnier, N; McEachan, R; Mäkelä, M; Mestres, J; Minina, E; Mowinckel, P; Nadif, R; Nawijn, M; Oddie, S; Pellet, J; Pin, I; Porta, D; Rancière, F; Rial-Sebbag, A; Saeys, Y; Schuijs, M J; Siroux, V; Tischer, C G; Torrent, M; Varraso, R; De Vocht, J; Wenger, K; Wieser, S; Xu, C

2016-11-01

MeDALL (Mechanisms of the Development of ALLergy; EU FP7-CP-IP; Project No: 261357; 2010-2015) has proposed an innovative approach to develop early indicators for the prediction, diagnosis, prevention and targets for therapy. MeDALL has linked epidemiological, clinical and basic research using a stepwise, large-scale and integrative approach: MeDALL data of precisely phenotyped children followed in 14 birth cohorts spread across Europe were combined with systems biology (omics, IgE measurement using microarrays) and environmental data. Multimorbidity in the same child is more common than expected by chance alone, suggesting that these diseases share causal mechanisms irrespective of IgE sensitization. IgE sensitization should be considered differently in monosensitized and polysensitized individuals. Allergic multimorbidities and IgE polysensitization are often associated with the persistence or severity of allergic diseases. Environmental exposures are relevant for the development of allergy-related diseases. To complement the population-based studies in children, MeDALL included mechanistic experimental animal studies and in vitro studies in humans. The integration of multimorbidities and polysensitization has resulted in a new classification framework of allergic diseases that could help to improve the understanding of genetic and epigenetic mechanisms of allergy as well as to better manage allergic diseases. Ethics and gender were considered. MeDALL has deployed translational activities within the EU agenda. © 2016 The Authors. Allergy Published by John Wiley & Sons Ltd.

Sonochemical coating of textile fabrics with antibacterial nanoparticles

NASA Astrophysics Data System (ADS)

Beddow, Jamie; Singh, Gagandeep; Blanes, María; Molla, Korina; Perelshtein, Ilana; Gedanken, Aharon; Joyce, Eadaoin; Mason, Timothy

2012-05-01

The high incidence of hospital-acquired infections places a huge financial burden on our healthcare systems. These infections are also responsible for many millions of deaths each year. Antibacterial fabrics for use in medical textiles, such as hospital uniforms, bedding and wound dressings, can provide a useful weapon in the on-going fight against these infections. The aim of this EU funded Framework 7 project is to develop a pilot line sonochemical coating machine for the production of antibacterial fabrics. The sonochemical coating technology under development is based on a lab scale process that was developed at Bar-Ilan University (BIU). It involves two processes that are driven by acoustic cavitation; the in situ generation of the metal oxide (MO) nanoparticles and the simultaneous high velocity propulsion of these nanoparticles onto a fabric leading to impregnation. Here we report on a comparison of 2 different MO nanoparticle coatings, ZnO and CuO, that were sonochemically applied on to a plain cotton fabric. Both of these coatings were prepared by BIU. In this work, the antibacterial efficacy of the coated fabrics was quantitatively assessed using the absorption method from BS EN ISO 20743:2007. Both types of metal oxide nanoparticle displayed antibacterial activity against all of the test bacteria with particularly high levels of bacterial reduction observed with the CuO coating. The results presented here are from an EU Framework 7 funded project (SONO, EU Project Number: 228730). The project is a collaboration between 17 partner organizations from 10 different European countries. Further details can be found on the project website at: www.fp7-sono.eu.

Learning from the experience: preliminary results of integration experiments within PRE-EARTHQUAKES EU-FP7 Project.

NASA Astrophysics Data System (ADS)

Tramutoli, V.; Inan, S.; Jakowski, N.; Pulinets, S.; Romanov, A.; Filizzola, C.; Shagimuratov, I.; Pergola, N.; Genzano, N.; Lisi, M.; Alparslan, E.; Wilken, V.; Tsybulia, K.; Romanov, A.; Paciello, R.; Balasco, M.; Zakharenkova, I.; Ouzounov, D.; Papadopoulos, G. A.; Parrot, M.

2012-04-01

PRE-EARTHQUAKES (Processing Russian and European EARTH observations for earthQUAKE precursors Studies) EU-FP7 project is devoted to demonstrate - integrating different observational data, comparing and improving different data analysis methods - how it is possible to progressively increase reliability of short term seismic risk assessment. Three main testing area were selected (Italy, Turkey and Sakhalin ) in order to concentrate observations and integration efforts starting with a learning phase on selected event in the past devoted to identify the most suitable parameters, observations technologies, data analysis algorithms. To this aim events offering major possibilities (variety) of integration were particularly considered - Abruzzo EQ (April 6th 2009 Mw 6.3) for Italy, Elazig EQ (March 8th 2010 Mw 6.1) for Turkey and Nevelsk EQ (August 2nd 2007 Mw 6.2) for Sakhalin - without excluding other significant events occurred during 2011 like the ones of Tōhoku in Japan and Van in Turkey. For these events, different ground (80 radon and 29 spring water stations in Turkey region, 2 magneto-telluric in Italy) and satellite (18 different systems) based observations, 11 data analysis methods, for 7 measured parameters, have been compared and integrated. Results achieved by applying a validation/confutation approach devoted to evaluate the presence/absence of anomalous space-time transients in single and/or integrated observation time-series will be discussed also in comparison with results independently achieved by other authors.

F-CHROMA.Flare Chromospheres: Observations, Models and Archives

NASA Astrophysics Data System (ADS)

Cauzzi, Gianna; Fletcher, Lyndsay; Mathioudakis, Mihalis; Carlsson, Mats; Heinzel, Petr; Berlicki, Arek; Zuccarello, Francesca

2014-06-01

F-CHROMA is a collaborative project newly funded under the EU-Framework Programme 7 "FP7-SPACE-2013-1", involving seven different European research Institutes and Universities. The goal of F-CHROMA is to substantially advance our understanding of the physics of energy dissipation and radiation in the flaring solar atmosphere, with a particular focus on the flares' chromosphere. A major outcome of the F-CHROMA project will be the creation of an archive of chromospheric flare observations and models to be made available to the community for further research.In this poster we describe the structure and milestones of the project, the different activities planned, as well as early results. Emphasis will be given to the dissemination efforts of the project to make results of these activities available to and usable by the community.

Reality check in the project management of EU funding

NASA Astrophysics Data System (ADS)

Guo, Chenbo

2015-04-01

A talk addressing workload, focuses, impacts and outcomes of project management (hereinafter PM) Two FP7 projects serve as objects for investigation. In the Earth Science sector NACLIM is a large scale collaborative project with 18 partners from North and West Europe. NACLIM aims at investigating and quantifying the predictability of the North Atlantic/Arctic sea surface temperature, sea ice variability and change on seasonal to decadal time scales which have a crucial impact on weather and climate in Europe. PRIMO from Political Science is a global PhD program funded by Marie Curie ITN instrument with 11 partners from Europe, Eurasia and BRICS countries focusing on the rise of regional powers and its impact on international politics at large. Although the two projects are granted by different FP7 funding instruments, stem from different cultural backgrounds and have different goals, the inherent processes and the key focus of the PM are quite alike. Only the operational management is at some point distinguished from one another. From the administrative point of view, understanding of both EU requirements and the country-specific regulations is essential; it also helps us identifying the grey area in order to carry out the projects more efficiently. The talk will focus on our observation of the day-to-day PM flows - primarily the project implementation - with few particular cases: transparency issues, e.g. priority settings of non-research stakeholders including the conflict in the human resources field, End-User integration, gender issues rising up during a monitoring visit and ethical aspects in field research. Through a brief comparison of both projects we summarize a range of dos and don'ts, an "acting instead of reacting" line of action, and the conclusion to a systematic overall management instead of exclusively project controlling. In a nutshell , the talk aims at providing the audience a summary of the observation in management methodologies and toolkits applied in both projects, our best practices and lessons learnt in coordinating large international consortia.

How to Apply for and Secure EU Funding for Collaborative IBD Research Projects

PubMed Central

Satsangi, Jack; Kitten, Olivier; Chavez, Marcela; Kalla, Rahul; Prel, Nadege; Meuwis, Marie-Alice; Scott, Stephanie; Bonetti, Illaria; Ventham, Nicholas T.

2016-01-01

The European Union offers opportunities for high-level of funding of collaborative European research. Calls are regularly published: after the end of the FP7 funding programme the new round of Horizon 2020 calls started in 2015. Several topics are relevant to inflammatory bowel disease (IBD) challenges, including chronic disease management, biomarker discovery and new treatments developments. The aim of this Viewpoint article is to describe the new Horizon 2020 instrument and the project submission procedures, and to highlight these through the description of tips and tricks, taking advantage of four examples of successful projects in the field of IBD: the SADEL, IBD-BIOM, IBD Character and BIOCYCLE projects. PMID:26744440

EU-China Environment Research: Enhancing collaboration through SPRING

NASA Astrophysics Data System (ADS)

Bray, Michaela; Han, Dawei

2013-04-01

There are huge challenges in both known and potential environmental problems in China and EU. Local geographical and climate conditions vary significantly across the two regions. For example the distribution of water resources is spatially and temporally uneven and often leads to water shortages in some areas, and flooding in others. In addition there is a sharp drop in mineral, oil and gas resources, as well as an increase in the living standard, which is a challenge for sustainable development. China's economy is still growing fast, placing an increased burden on the environment. The EU's economy is more developed with a rich experience in dealing with environmental problems in a fast growing economy. Therefore, it is mutually beneficial for the two sides to collaborate in environmental research. The FP7 funded SPRING project is intended to facilitate better EU-China environmental research cooperation and to create a long-term environment vision with clearly identifiable pathways for the two partners to work together. The project team is composed of five EU partners and five Chinese partners with expertise in water, soil, air, climate change and biodiversity. The project runs from March 2010-Feburary 2013. SPRING has taken a multi-level approach to achieving this, developing foresight and road-mapping studies to manage long term aims and facilitate increased cooperation and exchange for researchers, policy and decision makers and funding bodies. The outcomes of the project include detailed technology survey, success scenario analysis and EU-Horizon research road map with a focus on the research needs between EU and China in the next twenty years.

The iMars web-GIS - spatio-temporal data queries and single image web map services

NASA Astrophysics Data System (ADS)

Walter, S. H. G.; Steikert, R.; Schreiner, B.; Sidiropoulos, P.; Tao, Y.; Muller, J.-P.; Putry, A. R. D.; van Gasselt, S.

2017-09-01

We introduce a new approach for a system dedicated to planetary surface change detection by simultaneous visualisation of single-image time series in a multi-temporal context. In the context of the EU FP-7 iMars project we process and ingest vast amounts of automatically co-registered (ACRO) images. The base of the co-registration are the high precision HRSC multi-orbit quadrangle image mosaics, which are based on bundle-block-adjusted multi-orbit HRSC DTMs.

Sharing Water-related Information to Tackle Changes in the Hydrosphere - for Operational Needs (SWITCH-ON)

NASA Astrophysics Data System (ADS)

Arheimer, Berit

2015-04-01

Recently, a collaborative EU project started called SWITCH-ON (EU FP7 project No 603587) coordinated by SMHI to support the INSPIRE directive and the Open Data Strategy. The overall goal of the project is to establish a "one-stop-shop" web portal for easy access to European water information. The project will use open data, provide infrastructure for sharing and collaboration, and add value to society and research by repurposing and refining data from various sources. The SWITCH-ON project http://www.water-switch-on.eu/ will establish new forms of water research and facilitate the development of new products and services based on principles of sharing and community building in the water society. The SWITCH-ON objectives are to use open data for implementing: 1) an innovative spatial information platform (SIP) to find, bind, transform and publish data, 2) entirely new forms of collaborative research organised in a Virtual Water-Science Laboratory, open for any research group, 3) fourteen new operational products for water management and awareness, 4) outreach facilities for new water business and knowledge in line with the Europe's smart growth and environmental objectives. This poster will describe the overall project goals and especially the recent progress on developing a Virtual Water-Science Laboratory. Contact: waterswitchon@gmail.com

An integrated, open-source set of tools for urban vulnerability monitoring from Earth observation data

NASA Astrophysics Data System (ADS)

De Vecchi, Daniele; Harb, Mostapha; Dell'Acqua, Fabio; Aurelio Galeazzo, Daniel

2015-04-01

Aim: The paper introduces an integrated set of open-source tools designed to process medium and high-resolution imagery with the aim to extract vulnerability indicators [1]. Problem: In the context of risk monitoring [2], a series of vulnerability proxies can be defined, such as the extension of a built-up area or buildings regularity [3]. Different open-source C and Python libraries are already available for image processing and geospatial information (e.g. OrfeoToolbox, OpenCV and GDAL). They include basic processing tools but not vulnerability-oriented workflows. Therefore, it is of significant importance to provide end-users with a set of tools capable to return information at a higher level. Solution: The proposed set of python algorithms is a combination of low-level image processing and geospatial information handling tools along with high-level workflows. In particular, two main products are released under the GPL license: source code, developers-oriented, and a QGIS plugin. These tools were produced within the SENSUM project framework (ended December 2014) where the main focus was on earthquake and landslide risk. Further development and maintenance is guaranteed by the decision to include them in the platform designed within the FP 7 RASOR project . Conclusion: With the lack of a unified software suite for vulnerability indicators extraction, the proposed solution can provide inputs for already available models like the Global Earthquake Model. The inclusion of the proposed set of algorithms within the RASOR platforms can guarantee support and enlarge the community of end-users. Keywords: Vulnerability monitoring, remote sensing, optical imagery, open-source software tools References [1] M. Harb, D. De Vecchi, F. Dell'Acqua, "Remote sensing-based vulnerability proxies in the EU FP7 project SENSUM", Symposium on earthquake and landslide risk in Central Asia and Caucasus: exploiting remote sensing and geo-spatial information management, 29-30th January 2014, Bishkek, Kyrgyz Republic. [2] UNISDR, "Living with Risk", Geneva, Switzerland, 2004. [3] P. Bisch, E. Carvalho, H. Degree, P. Fajfar, M. Fardis, P. Franchin, M. Kreslin, A. Pecker, "Eurocode 8: Seismic Design of Buildings", Lisbon, 2011. (SENSUM: www.sensum-project.eu, grant number: 312972 ) (RASOR: www.rasor-project.eu, grant number: 606888 )

The EU-project United4Health: User-Centred Design and Evaluation of a Collaborative Information System for a Norwegian Telehealth Service.

PubMed

Smaradottir, Berglind; Gerdes, Martin; Martinez, Santiago; Fensli, Rune

2015-01-01

This study presents the user-centred design and evaluation process of a Collaborative Information System (CIS), developed for a new telehealth service for remote monitoring of chronic obstructive pulmonary disease patients after hospital discharge. The CIS was designed based on the information gathered in a workshop, where target end-users described the context of use, a telehealth workflow and their preferred ways of interaction with the solution. Evaluation of the iterative refinements were made through user tests, semi-structured interviews and a questionnaire. A field trial reported results on the ease of use and user satisfaction during the interaction with the fully developed system. The implemented CIS was successfully deployed within the secured Norwegian Health Network. The research was a result of cooperation between international partners within the EU FP7 project United4Health.

The GLObal Robotic telescopes Intelligent Array for e-science (GLORIA)

NASA Astrophysics Data System (ADS)

Castro-Tirado, A. J.; Sánchez Moreno, F. M.; Pérez del Pulgar, C.; Azócar, D.; Beskin, G.; Cabello, J.; Cedazo, R.; Cuesta, L.; Cunniffe, R.; González, E.; González-Rodríguez, A.; Gorosabel, J.; Hanlon, L.; Hudec, R.; Jakubek, M.; Janeček, P.; Jelínek, M.; Lara-Gil, O.; Linttot, C.; López-Casado, M. C.; Malaspina, M.; Mankiewicz, L.; Maureira, E.; Maza, J.; Muñoz-Martínez, V. F.; Nicastro, L.; O'Boyle, E.; Palazzi, E.; Páta, P.; Pio, M. A.; Prouza, M.; Serena, F.; Serra-Ricart, M.; Simpson, R.; Sprimont, P.; Strobl, J.; Topinka, M.; Vitek, S.; Zarnecki, A. F.

2015-05-01

GLORIA, funded under the auspices of the EU FP7 program in 2012--14, is a collaborative web--2.0 project based on a network of 18 robotic telescopes, which has become the first free-access network opened to the world for public outreach and specially for e-Science projects. On-line (solar and night) observations (experiments) as well as batch-mode (night) requests are possible. Educational material, applications (such as Personal Space) and complementary software have been also produced, besides the broadcast of several astronomical events during this period. GLORIA+ will exploit the full GLORIA potential in the years to come.

Support for EU fundraising in the field of Environment & Energy - BayFOR

NASA Astrophysics Data System (ADS)

Ammerl, Thomas; Baumann, Cornelia; Reiter, Andrea; Blume, Andreas; Just, Jana; Franke, Jan

2013-04-01

The Bavarian Research Alliance (BayFOR, http://www.bayfor.org) is a private company for the support of Bavaria (Free State in the South East of Germany) as a centre for science and innovation within the European Research Area. It was set up on the initiative of the Bavarian universities to strengthen their networking at regional, national and international level while helping them to prepare to meet the requirements for European research funding. The focus is directed at the current EU Framework Programme (FP7) and the forthcoming Framework Programme for Research and Innovation "Horizon 2020", but also comprises the wide range of European programmes (e.g. FP7, LIFE+, Interreg, COST, EUREKA, ERA-Nets, IEE (CIP), LLP, Calls for tender). BayFOR is also a partner institution in the Bavarian "Haus der Forschung" (www.hausderforschung.bayern.de/en). BayFORs overall aim is to strengthen and permanently anchor the science and innovation location of Bavaria in the European Research Area through: a) Initiation of national and in particular European innovation and science partnerships from academia and business b) Improvement of innovation potential of Bavarian universities and SME c) Support in acquisition, management and dissemination of results of European and international projects in the field of research and technological development The service portfolio of the EU Funding Advisory Service reaches from the first project idea to project implementation. The minimum condition for BayFOR support is at least one partner from Bavaria (Germany) must be part of the applying consortium: a) Recommendation of funding programmes/instruments (incl. integration of relevant EU policies & directives) b) Partner search c) Project development and proposal elaboration (Online platform, Creation of consortium, Attendance at meetings, Preparation of documents, Proposal structure elaboration, Provision of templates, Editorial support: Gantt, PERT, Impact, EU added value) d) Support in the Contract negotiations with the European Commission e) Project implementation (Project management, dissemination, Science-Policy-Interface) BayFOR staff has profound R&D background, as well as knowledge and experience in disseminating project outcomes, in particular with regard to the adaptation of results to the needs of relevant target groups like science, industry/SMEs, policy makers and the public. Furthermore, BayFOR can draw on distinct experience in the management of European research projects (e.g. CLIMB, Largecells, AlpBC, GeoMol, WE-EEN, WINALP). As a partner in the network for SMEs "Enterprise Europe Network" (EEN), BayFOR offers advice and support on topics such as funding, research programs, public procurement, market penetration and the promotion of innovation at European level. Beyond, BayFOR will make use of its regional networks to promote uptake and exploitation of project results. BayFOR is also commissioned by Bavaria's State Ministry of Science, Research and the Arts to look after the Bavarian University Funding Programme for the Initiation of International Projects (BayIntAn). Our efforts are aimed at initiating or strengthening transnational collaborative research involving Bavarian universities and universities of applied sciences.

Active Aging and Elderly's Quality of Life: Comparing the Impact on Literature of Projects Funded by the European Union and USA.

PubMed

Kirilov, I; Atzeni, M; Perra, A; Moro, D; Carta, M G

2018-01-01

The objective of this research is to verify whether European projects on Active Aging (AA) and Elderly Quality of Life (Qol) funded by the Seventh Framework Programme (FP7) produce an impact on literature similar to projects funded by the National Health Institute (NHI) of the United States on international literature using well-known bibliometric indicators. This effort may be useful in developing standardized and replicable procedures. Fifteen randomly selected projects on AA and Elderly Qol concluded in August 2017 and funded by FP7 were compared to similar projects funded by the US NHI with reference to papers published (Scopus and Scholar), papers published in Q1 journals, and the number of citations of the papers linked to the projects. In all the indicators considered, the European projects showed no difference with the US NHI projects. The EU-funded AA and Qol Elderly projects have an impact on scientific literature comparable to projects funded in the United States by the NHI Agency.Our results are consistent with the data on general medical research, which indicates that, European research remains at a high level of competitiveness.In this experimental study, our methodology appeared to be convincing and reliable and it could be applied to the extent of the impact of more extensive research areas.Our research did not evaluate the relationship between funding required by research and scientific productivity.

Destination bioeconomy - The path towards a smarter, more sustainable future.

PubMed

Dupont-Inglis, Joanna; Borg, Agnes

2018-01-25

Five years following the publication of the EU Bioeconomy Strategy, this article discusses the state of play of the bioeconomy in Europe. Placing specific focus on Industrial Biotech, it outlines ten pragmatic recommendations from BIO-TIC [BIO-TIC, A roadmap to a thriving industrial biotechnology sector in Europe, 2015], an EU FP7 funded project completed in 2015 and coordinated by EuropaBio, comprehensively examining the hurdles to the development of a bioeconomy in Europe, enabled by industrial biotech. These include improving opportunities for feedstock producers within the bioeconomy; investigating the scope for using novel biomass; developing a workforce which can maintain Europe's competitiveness in industrial biotechnology; introducing a long-term, stable and transparent policy and incentive framework to promote the bioeconomy; improving public perception and awareness of industrial biotechnology and bio-based products; identifying, leveraging and building upon EU capabilities for pilot and demonstration facilities; promoting the use of co-products from processing; improving the bioconversion and downstream processing steps; improving access to financing for large-scale biorefinery projects; developing stronger relationships between conventional and non-conventional players. Copyright © 2017. Published by Elsevier B.V.

A Worldwide Web-portal for Aquatic Mesocosm Facilities: WWW.MESOCOSM.EU

NASA Astrophysics Data System (ADS)

Berger, S. A.; Nejstgaard, J. C.

2016-02-01

Experimental mesocosms are valuable tools to fill the gap between highly controlled/replicated lab experiments and uncontrolled/non-replicated natural environments such as rivers, lakes and oceans. WWW.MESOCOSM.EU is an open web-portal for leading aquatic mesocosm facilities around the world. It was created within the FP7 EU-project MESOAQUA (A network of leading MESOcosm facilities to advance the studies of future AQUAtic ecosystems from the Arctic to the Mediterranean). The goal of the portal is to increase international knowledge about existing mesocosm facilities, including information on locations, environment, equipment, contacts, research opportunities and mesocosm-based publications. MESOCOSM.EU specifically aims to be a tool to enhance the quality of research by facilitating international cooperative network building, announcement of new research initiatives, transfer of best practice, and dissemination of knowledge, public information and press releases. As an open platform for all aquatic ecosystem scale science (marine and freshwater), MESOCOSM.EU aims to fill the lack of a centralized, coordinating virtual infrastructure for international aquatic mesocosm research, from the mountains to the ocean and from polar to tropical regions.

Astrobiology Road Mapping (AstRoMap) - A project within FP7 of the European Commission: First results

NASA Astrophysics Data System (ADS)

Gomez-Gomez, Felipe; Capria, Maria Teresa; Palomba, Ernesto; Walter, Nicolas; Rettberg, Petra; Muller, Christian; Horneck, Gerda

AstRoMap (Astrobiology and Planetary Exploration Road Mapping) is a funded project formulated in the 5th Call of the European Commission FP7 framework. The main objectives of the AstRoMap are: 1. Identify the main astrobiology issues to be addressed by Europe in the next decades in relation with space exploration 2. Identify potential mission concepts that would allow addressing these issues 3. Identify the technology developments required to enable these missions 4. Provide a prioritized roadmap integrating science and technology activities as well as ground-based approach 5. Map scientific knowledge related to astrobiology in Europe To reach those objectives, AstRoMap is executed within the following steps: 1. Community consultation. In order to map the European astrobiology landscape and to provide a collaborative networking platform for this community, the AstRoMap project hosts a database of scientists (European and beyond) interested in astrobiology and planetary exploration (see: http://www.astromap.eu/database.html). It reflects the demography and the research and teaching activities of the astrobiology community, as well as their professional profiles and involvement in astrobiology projects. Considering future aspects of astrobiology in Europe, the need for more astrobiology-dedicated funding programmes at the EU level, especially for cross-disciplinary groups, was stressed. This might eventually lead to the creation of a European laboratory of Astrobiology, or even of a European Astrobiology Institute. 2. Workshops organisation. On the basis of the feedbacks from the community consultation, the potential participants and interesting topics are being identified to take part in the following workshops: 1-. Origin of organic compounds, steps to life; 2. Physico-chemical boundary conditions for habitability 3. Biosignatures as facilitating life detection 4. Origin of the Solar system 3. Astrobiology road-mapping. Based on the results and major conclusions elaborated during the workshops, an astrobiology roadmap will be constructed tailored to the European needs and competences. 4. Education and public outreach. Parallel to the workshop and consultation activities, AstRoMap will provide a comprehensive education and outreach programme and disseminate the progress of AstRoMap through its web site (http://www.astromap.eu).

Tropospheric NO2 and HCHO columns derived from ground-based MAX-DOAS system in Guangzhou, China and comparison with satellite observations: First results within the EU FP7 project MarcoPolo

NASA Astrophysics Data System (ADS)

Drosoglou, Theano; Kouremeti, Natalia; Bais, Alkis; Zyrichidou, Irene; Li, Shu; Balis, Dimitris; Huang, Zhonghui

2016-04-01

A miniature MAX-DOAS system, Phaethon, has been developed at the Laboratory of Atmospheric Physics of the Aristotle University of Thessaloniki, Greece, for ground-based monitoring of column densities of atmospheric gases. Simultaneous measurements with two Phaethon systems at the city centre of Thessaloniki and at a rural location about 30 km away have shown that Phaethon provides NO2 and HCHO tropospheric column measurements of acceptable accuracy under both low and high air-pollution levels. Currently three systems have been deployed in areas with different pollution patterns to support air quality and satellite validation studies. In the framework of the EU FP7 Monitoring and Assessment of Regional air quality in China using space Observations, Project Of Long-term sino-european co-Operation, MarcoPolo project, one of the Phaethon systems has been installed since April 2015 in the Guangzhou region in China. Tropospheric NO2 and HCHO columns derived at Guangzhou during the first 10 months of operation are compared with corresponding retrievals from OMI/Aura and GOME-2/Metop-A and /Metop-B satellite sensors. The area is characterized by humid subtropical monsoon climate and cloud-free conditions are rather rare from early March to mid-October. Despite this limitation and the short period of operation of Phaethon in Guangzhou, the agreement between ground-based and satellite observations is generally good for both NO2 and HCHO. It appears that GOME-2 sensors seem to underestimate the tropospheric NO2, possibly due to their large pixel size, whereas the comparison with OMI data is better, especially when a small cloud fraction (< 0.2) is used for cloud screening.

DebugIT for patient safety - improving the treatment with antibiotics through multimedia data mining of heterogeneous clinical data.

PubMed

Lovis, Christian; Colaert, Dirk; Stroetmann, Veli N

2008-01-01

The concepts and architecture underlying a large-scale integrating project funded within the 7th EU Framework Programme (FP7) are discussed. The main objective of the project is to build a tool that will have a significant impact for the monitoring and the control of infectious diseases and antimicrobial resistances in Europe; This will be realized by building a technical and semantic infrastructure able to share heterogeneous clinical data sets from different hospitals in different countries, with different languages and legislations; to analyze large amounts of this clinical data with advanced multimedia data mining and finally apply the obtained knowledge for clinical decisions and outcome monitoring. There are numerous challenges in this project at all levels, technical, semantical, legal and ethical that will have to be addressed.

Teenagers and young adults with cancer in Europe: from national programmes to a European integrated coordinated project.

PubMed

Stark, D; Bielack, S; Brugieres, L; Dirksen, U; Duarte, X; Dunn, S; Erdelyi, D J; Grew, T; Hjorth, L; Jazbec, J; Kabickova, E; Konsoulova, A; Kowalczyk, J R; Lassaletta, A; Laurence, V; Lewis, I; Monrabal, A; Morgan, S; Mountzios, G; Olsen, P R; Renard, M; Saeter, G; van der Graaf, W T; Ferrari, A

2016-05-01

Over 14 000 patients aged 15-24 are estimated to be diagnosed with cancer in the European Union (EU) each year. Teenagers and young adults (TYA) often fall down gaps between children's and adults cancer services. The specific challenges of providing optimal care to them are described, but we present a summary of recent progress. Progress to overcome these challenges is happening at different rates across Europe. We summarise the European national projects in this field but more recently we have seen the beginnings of European coordination. Within the EU 7th Funding Programme (FP7) European Network for Cancer Research in Children and Adolescents programme (ENCCA), a specific European Network for Teenagers and Young Adults with Cancer has held a series of scientific meetings, including professionals, patients and caregivers. This group has proposed unanswered research questions and agreed key features of a high-quality service that can improve outcomes for TYA with cancer, including the primacy of collaboration between adult and paediatric services to eliminate the gap in the management of TYA with cancer. © 2015 John Wiley & Sons Ltd.

Influenza Vaccine Research funded by the European Commission FP7-Health-2013-Innovation-1 project.

PubMed

Liu, Heng; Frijlink, Henderik W; Huckriede, Anke; van Doorn, Eva; Schmidt, Ed; Leroy, Odile; Rimmelzwaan, Guus; McCullough, Keneth; Whelan, Mike; Hak, Eelko

2016-11-21

Due to influenza viruses continuously displaying antigenic variation, current seasonal influenza vaccines must be updated annually to include the latest predicted strains. Despite all the efforts put into vaccine strain selection, vaccine production, testing, and administration, the protective efficacy of seasonal influenza vaccines is greatly reduced when predicted vaccine strains antigenically mismatch with the actual circulating strains. Moreover, preparing for a pandemic outbreak is a challenge, because it is unpredictable which strain will cause the next pandemic. The European Commission has funded five consortia on influenza vaccine development under the Seventh Framework Programme for Research and Technological Development (FP7) in 2013. The call of the EU aimed at developing broadly protective influenza vaccines. Here we review the scientific strategies used by the different consortia with respect to antigen selection, vaccine delivery system, and formulation. The issues related to the development of novel influenza vaccines are discussed. Copyright © 2016 Elsevier Ltd. All rights reserved.

Monitoring Soil Infiltration In Semi-Arid Regions With Meteosat And A Coupled Model Approach Using PROMET And SLC

NASA Astrophysics Data System (ADS)

Klug, P.; Bach, H.; Migdall, S.

2013-12-01

In arid regions the infiltration of sparse rainfalls and resulting ground water recharge is a critical quantity for the water cycle. With the PROMET model the infiltration process can be simulated in detail, since 4 soil layers together with the hourly calculation time step allow simulating the vertical water transport. Wet soils are darker than dry soils. Using the SLC reflectance model this effect can be simulated and compared to temporal high resolution time series of measured reflectances from Meteosat in order to monitor the drying process. This study demonstrates how MSG can be used to better parameterize the simulation of the infiltration process and reduce uncertainties in ground water recharge estimation. The study is carried out in the frame of the EU FP7 project CLIMB (Climate Induced Changes on the Hydrology of Mediterranean Basins). According to climate projections, Mediterranean countries are at risk of changes in the hydrological budget, the agricultural productivity and drinking water supply in the future. The CLIMB FP-7 project coordinated by the University of Munich (LMU) aims at employing integrated hydrological modelling in a new framework to reduce existing uncertainties in climate change impact analysis of the Mediterranean region [1, 2].

Classification of Magnetic Nanoparticle Systems—Synthesis, Standardization and Analysis Methods in the NanoMag Project

PubMed Central

Bogren, Sara; Fornara, Andrea; Ludwig, Frank; del Puerto Morales, Maria; Steinhoff, Uwe; Fougt Hansen, Mikkel; Kazakova, Olga; Johansson, Christer

2015-01-01

This study presents classification of different magnetic single- and multi-core particle systems using their measured dynamic magnetic properties together with their nanocrystal and particle sizes. The dynamic magnetic properties are measured with AC (dynamical) susceptometry and magnetorelaxometry and the size parameters are determined from electron microscopy and dynamic light scattering. Using these methods, we also show that the nanocrystal size and particle morphology determines the dynamic magnetic properties for both single- and multi-core particles. The presented results are obtained from the four year EU NMP FP7 project, NanoMag, which is focused on standardization of analysis methods for magnetic nanoparticles. PMID:26343639

Ninety-day oral toxicity studies on two genetically modified maize MON810 varieties in Wistar Han RCC rats (EU 7th Framework Programme project GRACE).

PubMed

Zeljenková, Dagmar; Ambrušová, Katarína; Bartušová, Mária; Kebis, Anton; Kovrižnych, Jevgenij; Krivošíková, Zora; Kuricová, Miroslava; Líšková, Aurélia; Rollerová, Eva; Spustová, Viera; Szabová, Elena; Tulinská, Jana; Wimmerová, Soňa; Levkut, Mikuláš; Révajová, Viera; Ševčíková, Zuzana; Schmidt, Kerstin; Schmidtke, Jörg; La Paz, Jose Luis; Corujo, Maria; Pla, Maria; Kleter, Gijs A; Kok, Esther J; Sharbati, Jutta; Hanisch, Carlos; Einspanier, Ralf; Adel-Patient, Karine; Wal, Jean-Michel; Spök, Armin; Pöting, Annette; Kohl, Christian; Wilhelm, Ralf; Schiemann, Joachim; Steinberg, Pablo

2014-12-01

The GMO Risk Assessment and Communication of Evidence (GRACE; www.grace-fp7.eu ) project is funded by the European Commission within the 7th Framework Programme. A key objective of GRACE is to conduct 90-day animal feeding trials, animal studies with an extended time frame as well as analytical, in vitro and in silico studies on genetically modified (GM) maize in order to comparatively evaluate their use in GM plant risk assessment. In the present study, the results of two 90-day feeding trials with two different GM maize MON810 varieties, their near-isogenic non-GM varieties and four additional conventional maize varieties are presented. The feeding trials were performed by taking into account the guidance for such studies published by the EFSA Scientific Committee in 2011 and the OECD Test Guideline 408. The results obtained show that the MON810 maize at a level of up to 33 % in the diet did not induce adverse effects in male and female Wistar Han RCC rats after subchronic exposure, independently of the two different genetic backgrounds of the event.

New insights on short-term solar irradiance forecast for space weather applications

NASA Astrophysics Data System (ADS)

Vieira, L. A.; Dudok de Wit, T.; Balmaceda, L. A.; Dal Lago, A.; Da Silva, L. A.; Gonzalez, W. D.

2013-12-01

The conditions of the thermosphere, the ionosphere, the neutral atmosphere, and the oceans on time scales from days to millennia are highly dependent on the solar electromagnetic output, the solar irradiance. The development of physics-based solar irradiance models during the last decade improved significantly our understanding of the solar forcing on Earth's climate. These models are based on the assumption that most of the solar irradiance variability is related to the magnetic field structure of the Sun. Recently, these models were extended to allow short-term forecast (1 to 15 days) of the total and spectral solar irradiance. The extension of the irradiance models is based on solar surface magnetic flux models and/or artificial neural network models. Here, we discuss in details the irradiance forecast models based on observations of the solar surface magnetic field realized by the HMI instrument on board of SDO spacecraft. We constrained and validated the models by comparing the output of the models and observations of the solar irradiance made by instruments onboard The SORCE spacecraft. This study received funding from the European Community's Seventh Framework Programme (FP7/2007-2013, FP7-SPACE-2010-1) under the grant agreement nrs. 218816 (SOTERIA project, www.soteria-space.eu) and 261948 (ATMOP,www.atmop.eu), and by the CNPq/Brazil under the grant number 312488/2012-2. We also gratefully thank the instrument teams for making their data available.

Preliminary results from 2017 OGS Explora cruise to the Ross Sea continental slope

NASA Astrophysics Data System (ADS)

Rebesco, Michele; De Santis, Laura; Gales, Jenny; Kim, Sookwan; Liu, Yanguang; Sauli, Chiara; Cuffaro, Marco; Bergamasco, Andrea; Colleoni, Florence; Kovacevic, Vedrana; Olivo, Elisabetta; Florindo-Lopez, Cristian; Codiglia, Riccardo; Zgur, Fabrizio; Accettella, Daniela; Gordini, Emiliano; Visnovic, Paolo; Tomini, Isabella; Mansutti, Paolo; Sterzai, Paolo

2017-04-01

OGS Explora is back to Antarctica for three projects focused on the Ross Sea eastern continental slope: EU/FP7-EUROFLEETS (http://www.eurofleets.eu) ANTSSS, PNRA (Programma Nazionale Di Ricerche in Antartide) ODYSSEA, and PNRA WHISPERS. These projects employ three main methods: 1) geophysics (multichannel seismic reflection, sub-bottom and multibeam morphobathymetric survey); 2) geology (gravity corer and box-corer); oceanography (CTD, LADCP, turbulence). The general objective is to contribute to the understanding of past and present ocean dynamics and glacial history of this Antarctic sector. In particular, to find evidence (in the geometry and distribution of the stratigraphic sequences) of Miocene-Pleistocene West Antarctic Ice Sheet and East Antarctic Ice Sheet advances and retreats and of their effects on Ross Sea Bottom Water formation and dynamics. The gravity cores provide the chronological control for the Quaternary. Deep sea drilling (through IODP Exp. 374, whose additional alternative sites are surveyed during this cruise) will provide the chronological control for the pre-Quaternary seismic sequences.

Food safety management and risk assessment in the fresh produce supply chain

NASA Astrophysics Data System (ADS)

Jacxsens, L.; Uyttendaele, M.; Luning, P.; Allende, A.

2017-04-01

This paper is the output of several years of scientific research coordinated by Laboratory of Food Preservation and Food Microbiology at UGent, within the EU FP7 Research project Veg-i-trade (www.vegitrade.org), in collaboration with among other partners, Wageningen University and Cebas-CSIC. Fresh produce and derived products are globally traded and subjected to an inherent sensitive towards enteric pathogens as Salmonella and pathogenic E. coli due to their cultivation practices. As fruits and vegetables are increasingly being consumed raw, a potential health risk towards consumers is present. In the Veg-i-Trade project the extend of presence of pathogens in leafy greens and strawberry fruit and their cultivation environment (as water, soil, manured soil, etc.) was analysed. Insight in the food safety management system enlighted the need for further fostering and guidance towards farmers in good practices in order to reduce the potential pressure of the presence of the pathogens both in EU and non EU countries. Exposure assessment calculations demonstrated the usefulness of mathematic modelling to gain more insight in fragmented microbiological analysis and information of cultivation practices, as such the impact of contamination of irrigation water and the impact of a flooding event. Veg-i-Trade was a challenging project both in scientific and management perspective as 23 partners collaborated.

Ocean gliders as key component within the AORAC-SA

NASA Astrophysics Data System (ADS)

Barrera, C.; Hernandez Brito, J.; Castro, A.; Rueda, M. J.; Llinas, O.

2016-02-01

The Atlantic Ocean Research Alliance Coordination and Support Action (AORAC-SA) is designed to provide scientific, technical and logistical support to the EU in developing and implementing transAtlantic Marine Research Cooperation between the European Union, the United States of America and Canada. The Coordination and Support Action (CSA) is carried out within the framework of the Atlantic Ocean Research Alliance (AORA) as outlined in the Galway Statement on Atlantic Ocean Cooperation (May 2013). The CSA will be responsible for the organization of expert and stakeholder meetings, workshops and conferences required by the AORA and related to identified research priorities support actions and other initiatives as they arise, taking into account related Horizon 2020 supported transAtlantic projects and on-going national and EU collaborative projects. The AORAC-SA support and governance structure comprises a Secretariat and Management Team, guided by a high-level Operational Board, representative of the major European Marine Research Programming and Funding Organizations as well as those of the USA and Canada. As example of this research cooperative framework, ocean gliders have become nowadays a common, innovative and sustainable ocean-observations tool for the Atlantic basin, linking research groups, govermental institutions and private companies from both sides in terms of technical developments, transatlantic missions in partnership, training forums, etc. aiming to develop common practices and protocols for a better ocean resources management and understanding. Within this context, the Oceanic Platform of the Canary Islands (PLOCAN), as AORAC-SA partner, is working on specific actions like ocean glider observations programs (endurance line) by AtlantOS project (www.atlantos-h2020.eu), related new technical developments by NeXOS FP-7 project (www.nexosproject.eu) and a yearly International Glider School forum hosting (www.gliderschool.eu).

Economic losses to buildings due to tsunami impact: the case of Rhodes city, Greece

NASA Astrophysics Data System (ADS)

Triantafyllou, Ioanna; Novikova, Tatyana; Papadopoulos, Gerassimos

2017-04-01

The expected economic losses to buildings due to the tsunami impact is of particular importance for the tsunami risk management. However, only few efforts can be found in this direction. In this study we approached this issue selecting the city of Rhodes Isl., Greece, as a test-site. The methodological steps followed include (a) selection of worst case scenario in the study area based on the tsunami history of the area which includes several powerful events, e.g. 142 AD, 1303, 1481, 1609, 1741, (b) numerical simulation of the tsunami and determination of the inundation zone, (c) application of the DAMASCHE empirical tool, produced by the SCHEMA EU-FP6 project, for the calculation of the damage level expected at each one of the buildings as a function of the water depth in the inundation area, (d) calculation of the buildings that would need reparation after partial damage and of those that would need reconstruction after total destruction, (e) calculation of the cost implied for both reparation and reconstruction. The several data sets which are needed for the execution of these steps, are susceptible to uncertainties and, therefore, the final results are quite sensitive to changes of the data sets. Alternative costs were calculated by taking into account the several uncertainties involved. This research is a contribution to the EU-FP7 tsunami research project ASTARTE (Assessment, Strategy And Risk Reduction for Tsunamis in Europe), grant agreement no: 603839, 2013-10-30.

IASON - Fostering sustainability and uptake of research results through Networking activities in Black Sea & Mediterranean areas

NASA Astrophysics Data System (ADS)

Patias, P.

2014-09-01

IASON Project has the ultimate goal to establish a permanent and sustainable Network of scientific and non-scientific institutions, stakeholders and private sector enterprises belonging in the EU and third countries located in two significant areas: The Mediterranean and the Black Sea regions. The main focal points of the project will be the usage and application of Earth Observation (EO) in the following topics: - climate change - resource efficiency - raw materials management IASON aims to build on the experiences gained by 5 FP7 funded projects, OBSERVE, enviroGRIDS, GEONETCab, EGIDA, and BalkanGEONet. All of the above projects focused on enhancing EO capacities, knowledge and technology in the EU and in neighborhood countries. During their execution time they managed to establish links with a critical mass of research institutions, organizations, public organizations, stakeholders, and policy makers in the Balkan region, the Mediterranean, and the Black Sea Basin. IASON intends to create the proper conditions for enhancing knowledge transfer capacity building, and market opportunities in using EO applications and mechanisms in specific research fields that are addressing climate actions resource efficiency and raw materials management.

Environmental Impact of Megacities - Results from CityZen

NASA Astrophysics Data System (ADS)

Gauss, M.

2012-04-01

Megacities have increasingly important impacts on air quality and climate change on different spatial scales, owing to their high population densities and concentrated emission sources. The EU FP7 project CityZen (Megacity - Zoom for the Environment) ended in 2011 and was, together with its sister project MEGAPOLI, part of a major research effort within FP7 on megacities in Europe and worldwide. The project mainly focused on air pollution trends in large cities and emission hotspots, climate-chemistry couplings, future projections, and emission mitigation options. Both observational and modeling tools have been extensively used. This paper reviews some of the main results from CityZen regarding present air pollution in and around megacities, future scenarios and mitigation options to reduce air pollution and/or climate change, and the main policy messages from the project. The different observed trends over European and Asian hotspots during the last 10 to 15 years are shown. Results of source attribution of pollutants, which have been measured and calculated in and around the different selected hot spots in CityZen will be discussed. Another important question to be addressed is the extent to which climate change will affect air quality and the effectiveness of air quality legislation. Although projected emission reductions are a major determinate influencing the predictions of future air pollution, model results suggest that climate change has to be taken into account when devising future air quality legislation. This paper will also summarize some important policy messages in terms of ozone, particles and the observational needs that have been put forward as conclusions from the project.

Successful private-public funding of paediatric medicines research: lessons from the EU programme to fund research into off-patent medicines.

PubMed

Ruggieri, L; Giannuzzi, V; Baiardi, P; Bonifazi, F; Davies, E H; Giaquinto, C; Bonifazi, D; Felisi, M; Chiron, C; Pressler, R; Rabe, H; Whitaker, M J; Neubert, A; Jacqz-Aigrain, E; Eichler, I; Turner, M A; Ceci, A

2015-04-01

The European Paediatric Regulation mandated the European Commission to fund research on off-patent medicines with demonstrated therapeutic interest for children. Responding to this mandate, five FP7 project calls were launched and 20 projects were granted. This paper aims to detail the funded projects and their preliminary results. Publicly available sources have been consulted and a descriptive analysis has been performed. Twenty Research Consortia including 246 partners in 29 European and non-European countries were created (involving 129 universities or public-funded research organisations, 51 private companies with 40 SMEs, 7 patient associations). The funded projects investigate 24 medicines, covering 10 therapeutic areas in all paediatric age groups. In response to the Paediatric Regulation and to apply for a Paediatric Use Marketing Authorisation, 15 Paediatric Investigation Plans have been granted by the EMA-Paediatric Committee, including 71 studies of whom 29 paediatric clinical trials, leading to a total of 7,300 children to be recruited in more than 380 investigational centres. Notwithstanding the EU contribution for each study is lower than similar publicly funded projects, and also considering the complexity of paediatric research, these projects are performing high-quality research and are progressing towards the increase of new paediatric medicines on the market. Private-public partnerships have been effectively implemented, providing a good example for future collaborative actions. Since these projects cover a limited number of off-patent drugs and many unmet therapeutic needs in paediatrics remain, it is crucial foreseeing new similar initiatives in forthcoming European funding programmes.

NIL fabrication of a polymer-based photonic sensor device in P3SENS project

NASA Astrophysics Data System (ADS)

Giannone, Domenico; Dortu, Fabian; Bernier, Damien; Johnson, Nigel P.; Sharp, Graham J.; Hou, Lianping; Khokhar, Ali Z.; Fürjes, Péter; Kurunczi, Sándor; Petrik, Peter; Horvath, Robert; Aalto, Timo; Kolari, Kai; Ylinen, Sami; Haatainen, Tomi; Egger, Holger

2012-06-01

We present the most recent results of EU funded project P3SENS (FP7-ICT-2009.3.8) aimed at the development of a low-cost and medium sensitivity polymer based photonic biosensor for point of care applications in proteomics. The fabrication of the polymer photonic chip (biosensor) using thermal nanoimprint lithography (NIL) is described. This technique offers the potential for very large production at reduced cost. However several technical challenges arise due to the properties of the used materials. We believe that, once the NIL technique has been optimised to the specific materials, it could be even transferred to a kind of roll-to-roll production for manufacturing a very large number of photonic devices at reduced cost.

Dynamic Assessment of Seismic Risk (DASR) by Multi-parametric Observations: Preliminary Results of PRIME experiment within the PRE-EARTHQUAKES EU-FP7 Project

NASA Astrophysics Data System (ADS)

Tramutoli, V.; Inan, S.; Jakowski, N.; Pulinets, S. A.; Romanov, A.; Filizzola, C.; Shagimuratov, I.; Pergola, N.; Ouzounov, D. P.; Papadopoulos, G. A.; Parrot, M.; Genzano, N.; Lisi, M.; Alparlsan, E.; Wilken, V.; Tsybukia, K.; Romanov, A.; Paciello, R.; Zakharenkova, I.; Romano, G.

2012-12-01

The integration of different observations together with the refinement of data analysis methods, is generally expected to improve our present knowledge of preparatory phases of earthquakes and of their possible precursors. This is also the main goal of PRE-EARTHQUAKES (Processing Russian and European EARTH observations for earthQUAKE precursors Studies) the FP7 Project which, to this aim, committed together, different international expertise and observational capabilities, in the last 2 years. In the learning phase of the project, different parameters (e.g. thermal anomalies, total electron content, radon concentration, etc.), measured from ground and satellite systems and analyzed by using different data analysis approaches, have been studied for selected geographic areas and specific seismic events in the past. Since July 2012 the PRIME (PRE-EARTHQUAKES Real-time Integration and Monitoring Experiment) started attempting to perform, on the base of independent observations collected and integrated in real-time through the PEG (PRE-EARTHQUAKES Geo-portal), a Dynamic Assessment of Seismic Risk (DASR) on selected geographic areas of Europe (Italy-Greece-Turkey) and Asia (Kamchatka, Sakhalin, Japan). In this paper, results so far achieved as well as the potential and opportunities they open for a worldwide Earthquake Observation System (EQuOS) - as a dedicated component of GEOSS (Global Earth Observation System of Systems) - will be presented.

The MyOcean Thematic Assembly Centres: Satellite and In-situ Observation Services in Review

NASA Astrophysics Data System (ADS)

Hackett, Bruce; Breivik, Lars-Anders; Larnicol, Gilles; Pouliquen, Sylvie; Santoleri, Rosalia; Roquet, Hervé; Stoffelen, Ad

2015-04-01

The MyOcean (2009-2012), MyOcean2 (2012-2014) and MyOcean Follow-On (October 2014 - March 2015) projects, respectively funded by the EU's 7th Framework Programme for Research (FP7 2007-2013) and HORIZON 2020 (EU Research and Innovation programme 2014-2020), have been designed to prepare and to lead the demonstration phases of the nascent European Copernicus Marine Environment Monitoring Service (CMS). The observational component of the MyOcean services is embodied in four Thematic Assembly Centres (TACs): Three provide satellite-based products for sea level (SL-TAC), for ocean colour (OC-TAC) and for surface temperature, winds and sea ice (OSI-TAC), while the fourth provides in-situ observations (INS-TAC). All the TAC production is developed from existing capabilities and there is close collaboration with related national and European data providers. Data products include near-real-time data and multi-year reprocessed datasets. Data formatting, dissemination methods and documentation follow uniform MyOcean standards for ease of use. The presentation will track the evolution of the TAC services through the MyOcean projects up to the opening of the CMS.

Knowledge transfer within EU-funded marine science research - a viewpoint

NASA Astrophysics Data System (ADS)

Bayliss-Brown, Georgia; Cheallachaín, Cliona Ní

2016-04-01

Knowledge transfer, in its most inherent form, can be tracked back to the earliest phase of the Neolithic Revolution, 10,000 years ago, at a time when innovators shared their thoughts on crop cultivation and livestock farming (Bellwood, 2004). Not to be mistaken for science transfer - the export of modern science to non-scientific audiences - it was in the 1960s, that modern knowledge transfer was initiated, when reporting research achievements shifted towards having institutional and political agendas (Lipphardt & Ludwig, 2011). Albeit that the economic contribution of scientific research has been scrutinised for decades; today, there is a pronounced need for the evaluation of its social, cultural and ecological impact. To have impact, it is essential that scientific knowledge is clear and accessible, as well as robust and credible, so that it can be successfully transferred and applied by those identifying solutions for today's societal and environmental challenges. This phenomenon is receiving growing academic interest, where publications including "knowledge transfer" in the title have increased near exponentially for 60 years. Furthermore, we are seeing a definite shift towards embedding a mission of knowledge transfer in Public Research Organisations. This new approach is rewarding researchers whom deliver on all three institutional missions: teaching, research and knowledge transfer. In addition, the European Commission (2008) recommends that "knowledge transfer between universities and industry is made a permanent political and operational priority" and that "sufficient resources and incentives [be] available to public research organisations and their staff to engage in knowledge transfer activities". It is also anticipated that funding agencies will soon make pathways-to-impact statements, also known as knowledge transfer plans, a mandatory requirement of all project proposals. AquaTT is a leader in scientific knowledge management, including knowledge transfer and dissemination. This Dublin-based SME has an ever-growing portfolio of FP7 and Horizon 2020 projects where they hold knowledge management responsibilities. In this session, we will present AquaTT's experiences in knowledge management for several European Union-funded marine research projects; including MarineTT (http://marinett.eu/) that was recognised as an exemplar project in the ex post evaluation of FP7 to the European Commission. These insights will be supplemented with an overview of the AquaTT-developed step-by-step knowledge transfer methodology, as used by the COLUMBUS project - the EU's flagship Blue Growth and Knowledge Transfer initiative (http://www.columbusproject.eu/). This session will provide a platform to launch AquaTT's European knowledge transfer network, established to support the research community in fostering a culture that recognises and rewards knowledge transfer between scientists and end-users (industry, policy, and wider society), thereby ensuring that research achieves its maximum potential impact. References Bellwood, P. (2004) The First Farmers: Origins of Agricultural Societies. Malden, MA. European Commission (2008) recommendation on the management of intellectual property in knowledge transfer activities and code of practice for universities and other public research organisations http://ec.europa.eu/invest-in-research/pdf/ip_recommendation_en.pdf Lipphardt, V. and D. Ludwig (2011) Knowledge transfer and science transfer. http://ieg-ego.eu/en/threads/theories-and-methods/knowledge-transfer/veronika-lipphardt-david-ludwig-knowledge-transfer-and-science-transfer

CFD analysis of aircraft fuel tanks thermal behaviour

NASA Astrophysics Data System (ADS)

Zilio, C.; Longo, G. A.; Pernigotto, G.; Chiacchio, F.; Borrelli, P.; D'Errico, E.

2017-11-01

This work is carried out within the FP7 European research project TOICA (Thermal Overall Integrated Conception of Aircraft, http://www.toica-fp7.eu/). One of the tasks foreseen for the TOICA project is the analysis of fuel tanks as possible heat sinks for future aircrafts. In particular, in the present paper, commercial regional aircraft is considered as case study and CFD analysis with the commercial code STAR-CCM+ is performed in order to identify the potential capability to use fuel stored in the tanks as a heat sink for waste heat dissipated by other systems. The complex physical phenomena that characterize the heat transfer inside liquid fuel, at the fuel-ullage interface and inside the ullage are outlined. Boundary conditions, including the effect of different ground and flight conditions, are implemented in the numerical simulation approach. The analysis is implemented for a portion of aluminium wing fuel tank, including the leading edge effects. Effect of liquid fuel transfer among different tank compartments and the air flow in the ullage is included. According to Fuel Tank Flammability Assessment Method (FTFAM) proposed by the Federal Aviation Administration, the results are exploited in terms of exponential time constants and fuel temperature difference to the ambient for the different cases investigated.

Accelerator science and technology in Europe 2008-2017

NASA Astrophysics Data System (ADS)

Romaniuk, Ryszard S.

2013-10-01

European Framework Research Projects have recently added a lot of meaning to the building process of the ERA - the European Research Area. Inside this, the accelerator technology plays an essential role. Accelerator technology includes large infrastructure and intelligent, modern instrumentation embracing mechatronics, electronics, photonics and ICT. During the realization of the European research and infrastructure project FP6 CARE 2004-2008 (Coordinated Accelerator Research in Europe), concerning the development of large accelerator infrastructure in Europe, it was decided that a scientific editorial series of peer-reviewed monographs from this research area will be published in close relation with the projects. It was a completely new and quite brave idea to combine a kind of a strictly research publisher with a transient project, lasting only four or five years. Till then nobody did something like that. The idea turned out to be a real success. The publications now known and valued in the accelerator world, as the (CERN-WUT) Editorial Series on Accelerator Science and Technology, is successfully continued in already the third European project EuCARD2 and has logistic guarantees, for the moment, till the 2017, when it will mature to its first decade. During the realization of the European projects EuCARD (European Coordination for Accelerator R&D 2009-2013 and TIARA (Test Infrastructure of Accelerator Research Area in Europe) there were published 18 volumes in this series. The ambitious plans for the nearest years is to publish, hopefully, a few tens of new volumes. Accelerator science and technology is one of a key enablers of the developments in the particle physic, photon physics and also applications in medicine and industry. The paper presents a digest of the research results in the domain of accelerator science and technology in Europe, published in the monographs of the European Framework Projects (FP) on accelerator technology. The succession of CARE, EuCARD and EuCARD Projects is evidently creating a new quality in the European Accelerator Research. It is consolidating the technical and research communities in a new way, completely different than the traditional ones, for example via the periodic topical conferences.

Hypoxia monitoring activities within the FP7 EU-project HYPOX: diverse approaches to understand a complex phenomenon

NASA Astrophysics Data System (ADS)

Janssen, F.; Waldmann, C.; Boetius, A.

2012-04-01

Hypoxic conditions in aquatic systems and the occurrence of 'dead zones' increase worldwide due to man-made eutrophication and global warming with consequences for biodiversity, ecosystem functions and services such as fisheries, aquaculture and tourism. Monitoring of hypoxia and its consequences has to (1) account for the appropriate temporal and spatial scales, (2) separate anthropogenic from natural drivers and long-term trends from natural variations, (3) assess ecosystem response, (4) use modeling tools for generalization and prediction, and (5) share data and obtained knowledge. In 2009 the EU FP7 project HYPOX (www.hypox.net) started out as a pioneering attempt to improve and integrate hypoxia observation capacities addressing these requirements. Target ecosystems selected for HYPOX cover a broad range of settings (e.g., hydrography, oxygenation status, biological activity, anthropogenic impact) and differ in their sensitivity towards change. Semi-enclosed basins with permanent anoxia (Black Sea, Baltic Sea), are included as well as seasonally or locally hypoxic land-locked systems (fjords, lagoons, lakes) and open ocean systems with high sensitivity to global warming (North Atlantic - Arctic transition). Adopted monitoring approaches involve autonomous, cabled, and shipboard instruments and include static and profiling moorings, benthic observatories, drifters, as well as classical CTD surveys. In order to improve observatory performance, project activities encompass developments of oxygen sensors as well as calibration procedures and technologies to reduce biofouling. Modeling and data assimilation are used to synthesize findings, to obtain an in-depth understanding of hypoxia causes and consequences, and to improve forecasting capacities. For integration of the collected information into a global oxygen observing system, results are disseminated through the HYPOX portal following GEOSS data sharing principles. This presentation will give an overview of the scientific approach of HYPOX and highlight some key results comprising findings from individual ecosystems and indentified general patterns. The driving forces that lead to hypoxia are assessed as well as consequences of oxygen depletion for aquatic life and biogeochemical processes.

Description of an 8 MW reference wind turbine

NASA Astrophysics Data System (ADS)

Desmond, Cian; Murphy, Jimmy; Blonk, Lindert; Haans, Wouter

2016-09-01

An 8 MW wind turbine is described in terms of mass distribution, dimensions, power curve, thrust curve, maximum design load and tower configuration. This turbine has been described as part of the EU FP7 project LEANWIND in order to facilitate research into logistics and naval architecture efficiencies for future offshore wind installations. The design of this 8 MW reference wind turbine has been checked and validated by the design consultancy DNV-GL. This turbine description is intended to bridge the gap between the NREL 5 MW and DTU 10 reference turbines and thus contribute to the standardisation of research and development activities in the offshore wind energy industry.

Towards Semantic Modelling of Business Processes for Networked Enterprises

NASA Astrophysics Data System (ADS)

Furdík, Karol; Mach, Marián; Sabol, Tomáš

The paper presents an approach to the semantic modelling and annotation of business processes and information resources, as it was designed within the FP7 ICT EU project SPIKE to support creation and maintenance of short-term business alliances and networked enterprises. A methodology for the development of the resource ontology, as a shareable knowledge model for semantic description of business processes, is proposed. Systematically collected user requirements, conceptual models implied by the selected implementation platform as well as available ontology resources and standards are employed in the ontology creation. The process of semantic annotation is described and illustrated using an example taken from a real application case.

Analysis of uses and competitions of water resources or an original dissemination strategy of hydrological modelling results of an EU project ?

NASA Astrophysics Data System (ADS)

La Jeunesse, Isabelle; Fustec, Klervi; Larrue, Corinne; Trottier, Julie

2010-05-01

We propose to address the question of security threats through an analysis of water uses and competitions in the current situation, on one hand, and in conditions of climate change, on the other hand, in order to have an operational dissemination of hydrological modelling results. This will be carried out for each case study of the EU project CLIMB (7th EU FP). In this particular case, climate change impacts are to be considered in relation with water uses and rivalries. Taking them into account while involving stakeholders should allow us to have a deep impact on water uses regulation under conditions of climate change. The originality of this methodology, the first objective of which within the project is to disseminate project results and interact with stakeholders, is to use the dissemination phase as a means of involving stakeholder knowledge concerning water uses and competitions. The idea is to let the stakeholders identify themselves, in each case study, by means of interactive methods, the impact of the change of hydrological regime on their own water uses and competitions. We propose to use a real "bottom-up" strategy to assess the potential water uses and rivalries in the context of water scarcity (or flood) due to climate change. Such an approach will allow us to evaluate the risk of an increase in water rivalries and threats to security following climate change impacts scenarios at the river basin scale.

New advances in the integrated management of food processing by-products in Europe: sustainable exploitation of fruit and cereal processing by-products with the production of new food products (NAMASTE EU).

PubMed

Fava, Fabio; Zanaroli, Giulio; Vannini, Lucia; Guerzoni, Elisabetta; Bordoni, Alessandra; Viaggi, Davide; Robertson, Jim; Waldron, Keith; Bald, Carlos; Esturo, Aintzane; Talens, Clara; Tueros, Itziar; Cebrián, Marta; Sebők, András; Kuti, Tunde; Broeze, Jan; Macias, Marta; Brendle, Hans-Georg

2013-09-25

By-products generated every year by the European fruit and cereal processing industry currently exceed several million tons. They are disposed of mainly through landfills and thus are largely unexploited sources of several valuable biobased compounds potentially profitable in the formulation of novel food products. The opportunity to design novel strategies to turn them into added value products and food ingredients via novel and sustainable processes is the main target of recently EC-funded FP7 project NAMASTE-EU. NAMASTE-EU aims at developing new laboratory-scale protocols and processes for the exploitation of citrus processing by-products and wheat bran surpluses via the production of ingredients useful for the formulation of new beverage and food products. Among the main results achieved in the first two years of the project, there are the development and assessment of procedures for the selection, stabilization and the physical/biological treatment of citrus and wheat processing by-products, the obtainment and recovery of some bioactive molecules and ingredients and the development of procedures for assessing the quality of the obtained ingredients and for their exploitation in the preparation of new food products. Copyright © 2013 Elsevier B.V. All rights reserved.

Learning from the past for TB drug discovery in the future

PubMed Central

Mikušová, Katarína; Ekins, Sean

2016-01-01

Tuberculosis drug discovery has shifted in recent years from a primarily target-based approach to one that uses phenotypic high-throughput screens. As examples of this, through our EU-funded FP7 collaborations, New Medicines for Tuberculosis was target-based and our more-recent More Medicines for Tuberculosis project predominantly used phenotypic screening. From these projects we have examples of success (DprE1) and failure (PimA) going from drug to target and from target to drug, respectively. It is clear that we still have much to learn about the drug targets and the complex effects of the drugs on Mycobacterium tuberculosis. We propose a more integrated approach that learns from earlier drug discovery efforts that could help to move drug discovery forward. PMID:27717850

A 50-year precipitation analysis over Europe at 5.5km within the UERRA project

NASA Astrophysics Data System (ADS)

Bazile, Eric; Abida, Rachid; Soci, Cornel; Verrelle, Antoine; Szczypta, Camille; Le Moigne, Patrick

2017-04-01

The UERRA project is a 4-year project (2014-2017) financed by the European Union under its 7th Framework Programme SPACE. One of its main objectives is to provide a 50-year reanalysis dataset of surface essential climate variables (ECV) at 5.5km grid at European scale, together with, as much as possible, uncertainty estimates. One of the ECV is the precipitation and this variable is of essential interest in weather forecasting, climate study and to "drive" hydrological model for water management, or agrometeorology. After a brief description of the method used for the precipitation analysis (Soci et al. 2016)during this project, the preliminary results will be presented. The estimation of uncertainties will be also discussed associated with the problem of the evolution of the observation density network and its impact on the long term series. Additional information about the UERRA project can be found at http://www.uerra.eu The research leading to these results has received funding from the European Union, Seventh Framework Programme (FP7-SPACE-2013-1) under grant agreement no 607193.

Open data for water-related operational services, the SWITCH-ON approach

NASA Astrophysics Data System (ADS)

Mazzoli, Paolo; Bagli, Stefano; Valerio, Luzzi; Broccoli, Davide; Piccinini, Francesca

2017-04-01

Recently, a collaborative project started called SWITCH-ON (EU FP7 project No 603587) coordinated by SMHI (http://water-switch-on.eu/) as part of the contemporary European movement imposed by the INSPIRE directive and the Open Data Strategy. Among It's R&D activities GECOsistema develops and expands inside SWITCH-ON a set of online services to tackle major water related issues, from reservoir and irrigation supply, to hydrological change adaptation and hydropower potential mapping. Here we present major releases of APRIL, HyCAW and High-resolution European HydroPower Atlas; all of which make intense use of open data. APRIL is a tool for seasonal run-off forecasts, that takes advantage of open datasets or low-cost data and performs forecasts through calibrated machine learning algorithms. HyCAW is a wizard that supports the assessment of adaptation options to cope with change in the temporal distribution of water availability as well as in the total water quantity. EU HPA provides all relevant information necessary to appraise the feasibility of a micro-hydropower plant at a specific site, taking into account hydrological as well as technical and economic factors. All the tools share a common vision of the project to address water concerns and currently untapped potential of open data for improved water management across the EU. Users are guided through a Web GIS interface, created using open source Web Mapping Applications, Open-Layers and Map Server, to explore available hydrological information in the area of interest, plot available data, perform analysis, and get reports and statistics.

HCHO and NO2 MAXDOAS retrieval strategies harmonization: Recent results from the EU FP7 project QA4ECV

NASA Astrophysics Data System (ADS)

Pinardi, Gaia; Peters, Enno; Hendrick, François; Gielen, Clio; Van Roozendael, Michel; Richter, Andreas; Piters, Ankie; Wagner, Thomas; Wang, Yang; Drosoglou, Theano; Bais, Alkis; Wang, Shanshan; Saiz-Lopez, Alfonso

2016-04-01

During the last decade, it has been extensively demonstrated that MAXDOAS is a useful and reliable technique to retrieve integrated column amounts of tropospheric trace gases and aerosols, as well as information on their vertical distributions. Since it is based on optical remote-sensing in the UV-visible region like nadir backscatter space-borne sensors, MAXDOAS is also increasingly recognized as a reference technique for validating satellite nadir observations of air quality species like NO2 and HCHO. However, building up an harmonized network of MAXDOAS spectrometers requires significant efforts in terms of common retrieval strategies and best-practices definitions. Within the EU FP7 project QA4ECV (Quality Assurance for Essential Climate Variables; see http://www.qa4ecv.eu/), harmonization activities have been initiated focusing on the two main steps of the MAXDOAS retrieval, i.e. the DOAS spectral fit providing the so-called differential slant column densities (DSCDs) and the conversion of the retrieved DSCDs to vertical profiles and/or vertical column densities (VCDs). Regarding the first step, the DOAS settings for HCHO and NO2 are optimized through an intercomparison exercise of slant column retrievals involving 15 groups of the MAXDOAS community including the QA4ECV partners, and based on the radiance spectra acquired during the MAD-CAT campaign held in Mainz (Germany) in June-July 2013 (see http://joseba.mpch-mainz.mpg.de/mad_cat.htm). The harmonization of the second step is done through the application of an AMF (aim mass factor) look-up table (LUT) approach on the optimized NO2 and HCHO DSCDs. The AMF LUTs depend on entry parameters like SZA, elevation and relative azimuth angles, wavelength, boundary layer height, AOD, and surface albedo. The advantages and drawbacks of the LUT approach are illustrated at several stations through comparison of the derived VCDs with those retrieved using the more sophisticated Optimal-Estimation-based profiling method. Recommendations for both MAXDOAS retrieval steps will be given in conclusion.

Local Wind Influence on Freshwater Plume Behavior: Application to the Catalan Shelf.

NASA Astrophysics Data System (ADS)

Liste, Maria; Grifoll, Manel; Monbaliu, Jaak; Keupers, Ingrid; Komijani, Homayoon

2013-04-01

Introduction Freshwater fluxes are not always considered, and often their 3D character is neglected. The "distributed" continental run-off is seldom taken into consideration. The main aim of the EU-FP7 Field_Ac project (www.field_ac.eu), was to improve operational service for coastal areas and to generate added value for shelf and regional scale predictions including land discharge as a boundary condition. In this paper the dispersal of a fresh water plume in a small part of the Catalan Coast (NW Mediterranean Sea) caused by a flash flood event in March 2011 is presented in response to the local wind forcing. Observations and modeling results are shown for a short period but with a large impact on the receiving coastal waters. Methodology and aim For the coastal circulation model, version 3.0 of the Regional Ocean Modeling System [ROMS, Shchepetkin and McWilliams, 2005] has been chosen. ROMS solves the 3-D Reynolds-Averaged Navier-Stokes equations in sigma coordinates. The code design is modular, so that different choices for advection and mixing, for example, may be applied by simply modifying preprocessor flags. Nested increasing-resolution models have been implemented in order to reproduce with sufficient spatial resolution the coastal circulation and the river plume evolution in a small portion of the Catalan coastal area. The boundary conditions for the largest domain model are obtained from the MyOcean products. River and urban run-off are estimated based on measured or predicted rainfall in the contributing catchments areas. Conceptual models based on a reservoir-type schematization of the river and sewer network have been set up to allow for fast prediction of the different point source boundary conditions [Keupers et al., 2011]. Model output data are compared to in situ data from dedicated campaigns during the Field_AC Project and to data from operational buoys in the Catalan coastal area. Results Wind forcing leads to freshwater spreading. As expected, wind speed and direction and the magnitude of the fresh water discharge affect substantially the plume behavior. This case study illustrates clearly the need to consider both the wind forcing and the fresh water discharge as part of a single system. References Field_AC project (www.field_ac.eu), EU- FP7-SPACE-2009-1-242284. Keupers, I., Willems, P., Fernandez Sainz, J., Bricheno, L., Wolf, J., Polton, J., Howarth, J., Carniel, S., Staneva, J. (2011). Methodology (including best practice guidelines) on how to identify and incorporate 'concentrated' and 'distributed' run-off in pre-operational forecasts, based on the input and requirements from our users. FIELD_AC project, D3.1, 90 pp. MyOcean products (http://www.myocean.eu/). Shchepetkin and McWilliams, 2005. The Regional Ocean Modeling System (ROMS): A split-explicit, free-surface, topography-following coordinates ocean model. Ocean Modelling. Vol. 9 pp. 347-404.

Earth-Observation based mapping and monitoring of exposure change in the megacity of Istanbul: open-source tools from the MARSITE project

NASA Astrophysics Data System (ADS)

De Vecchi, Daniele; Dell'Acqua, Fabio

2016-04-01

The EU FP7 MARSITE project aims at assessing the "state of the art" of seismic risk evaluation and management at European level, as a starting point to move a "step forward" towards new concepts of risk mitigation and management by long-term monitoring activities carried out both on land and at sea. Spaceborne Earth Observation (EO) is one of the means through which MARSITE is accomplishing this commitment, whose importance is growing as a consequence of the operational unfolding of the Copernicus initiative. Sentinel-2 data, with its open-data policy, represents an unprecedented opportunity to access global spaceborne multispectral data for various purposes including risk monitoring. In the framework of EU FP7 projects MARSITE, RASOR and SENSUM, our group has developed a suite of geospatial software tools to automatically extract risk-related features from EO data, especially on the exposure and vulnerability side of the "risk equation" [1]. These are for example the extension of a built-up area or the distribution of building density. These tools are available open-source as QGIS plug-ins [2] and their source code can be freely downloaded from GitHub [3]. A test case on the risk-prone mega city of Istanbul has been set up, and preliminary results will be presented in this paper. The output of the algorithms can be incorporated into a risk modeling process, whose output is very useful to stakeholders and decision makers who intend to assess and mitigate the risk level across the giant urban agglomerate. Keywords - Remote Sensing, Copernicus, Istanbul megacity, seismic risk, multi-risk, exposure, open-source References [1] Harb, M.M.; De Vecchi, D.; Dell'Acqua, F., "Physical Vulnerability Proxies from Remotes Sensing: Reviewing, Implementing and Disseminating Selected Techniques," Geoscience and Remote Sensing Magazine, IEEE , vol.3, no.1, pp.20,33, March 2015. doi: 10.1109/MGRS.2015.2398672 [2] SENSUM QGIS plugin, 2016, available online at: https://plugins.qgis.org/plugins/sensum_eo_tools/ [3] SENSUM QGIS code repository, 2016, available online at: https://github.com/SENSUM-project/sensum_rs_qgis

The EU paediatric regulation: still a large discrepancy between therapeutic needs and approved paediatric investigation plans.

PubMed

Wimmer, Stefan; Rascher, Wolfgang; McCarthy, Suzanne; Neubert, Antje

2014-10-01

Prior to the implementation of the EU Paediatric Regulation, the European Medicines Agency (EMA) defined unmet paediatric needs for active substances already available on the market. Seven years after the Paediatric Regulation came into force, we investigated the extent to which previously identified needs have led to programmes for generating evidence necessary for the regulatory approval of medicines for managing childhood conditions. The websites of the EMA and the European Commission Community Research and Development Information Service (CORDIS) were systematically screened to identify active substances from the assessment of paediatric needs, off-patent priority list, agreed Paediatric Investigation Plans (PIP) and 7th Framework Programme (FP7) projects related to paediatric medicines. A total of 357 active substances with paediatric needs were identified by June 2013. 511 PIPs were agreed by the Paediatric Committee at the EMA (PDCO), including 51 (14.3 %) PIPs for a previously identified need. Amongst those, 21 were off-patent at the time of the PIP approval, 15 of which received funding from the European Commission's FP7. According to the assessment of paediatric needs, evidence is particularly needed for active substances treating cardiovascular diseases (n = 61), cancer (n = 40) and in the field of anaesthesiology (n = 38). Whereas oncology drugs (n = 66) were frequently represented in PIPs, drugs for cardiovascular diseases (n = 39) and anaesthesiology (n = 3) rarely were. Most PIPs are attributable to marketing authorisations of new active substances, whereas off-patent drugs which are commonly used off-label remain unstudied to a large extent. More effort including ongoing research funding is essential to further regularise and standardise paediatric pharmacotherapy.

New approaches in human health risk assessment.

PubMed

Abass, Khaled; Carlsen, Anders; Rautio, Arja

2016-01-01

Studies on the precise impact of environmental pollutants on human health are difficult to undertake and interpret, because many genetic and environmental factors influence health at the same time and to varying degrees. Our chapter in the AMAP report was based on new approaches to describe risks and future needs. In this paper, we will introduce the issues associated with risk assessment of single chemicals, and present suggestions for future studies as well as a summary of lessons learned during the health-related parts of the European Union-funded FP7 project ArcRisk (Arctic Health Risks: Impacts on health in the Arctic and Europe owing to climate-induced changes in contaminant cycling, 2009-2014; www.arcrisk.eu).

High resolution, wide field of view, real time 340GHz 3D imaging radar for security screening

NASA Astrophysics Data System (ADS)

Robertson, Duncan A.; Macfarlane, David G.; Hunter, Robert I.; Cassidy, Scott L.; Llombart, Nuria; Gandini, Erio; Bryllert, Tomas; Ferndahl, Mattias; Lindström, Hannu; Tenhunen, Jussi; Vasama, Hannu; Huopana, Jouni; Selkälä, Timo; Vuotikka, Antti-Jussi

2017-05-01

The EU FP7 project CONSORTIS (Concealed Object Stand-Off Real-Time Imaging for Security) is developing a demonstrator system for next generation airport security screening which will combine passive and active submillimeter wave imaging sensors. We report on the development of the 340 GHz 3D imaging radar which achieves high volumetric resolution over a wide field of view with high dynamic range and a high frame rate. A sparse array of 16 radar transceivers is coupled with high speed mechanical beam scanning to achieve a field of view of 1 x 1 x 1 m3 and a 10 Hz frame rate.

Preliminary test of the prototype modular cryostat for a 10 MW offshore superconducting wind turbine

NASA Astrophysics Data System (ADS)

Sun, Jiuce; Ramalingam, R.; Sanz, Santiago; Neumann, Holger

2017-02-01

The SUPerconducting Reliable lightweight And more POWERful offshore wind turbine (SUPRAPOWER), an EU FP7 funded research project, are under development for an innovative superconducting 10 MW class offshore wind turbine. Due to the requirements of handling, maintenance, reliability of long term and offshore operation, the cryostats are divided in two major parts: the modular cryostat able to accommodate a single coil and a thermal collector that links all the modules. The prototype modular cryostat was designed, manufactured and assembled in Karlsruhe Institute of Technology (KIT). The paper reports preliminary test results of proto-type modular cryostat with a two-stage Gifford-McMahon (GM) cryocooler.

Recent progress in Open Data production and consumption - examples from a Governmental institute (SMHI) and a collaborative EU research project (SWITCH-ON)

NASA Astrophysics Data System (ADS)

Arheimer, Berit; Falkenroth, Esa

2014-05-01

The Swedish Meteorological and Hydrological Institute (SMHI) has a long tradition both in producing and consuming open data on a national, European and global scale. It is also promoting community building among water scientists in Europe by participating in and initiating collaborative projects. This presentation will exemplify the contemporary European movement imposed by the INSPIRE directive and the Open Data Strategy, by showing the progress in openness and shift in attitudes during the last decade when handling Research Data and Public Sector Information at a national European institute. Moreover, the presentation will inform about a recently started collaborative project (EU FP7 project No 603587) coordinated by SMHI and called SWITCH-ON http://water-switch-on.eu/. The project addresses water concerns and currently untapped potential of open data for improved water management across the EU. The overall goal of the project is to make use of open data, and add value to society by repurposing and refining data from various sources. SWITCH-ON will establish new forms of water research and facilitate the development of new products and services based on principles of sharing and community building in the water society. The SWITCH-ON objectives are to use open data for implementing: 1) an innovative spatial information platform with open data tailored for direct water assessments, 2) an entirely new form of collaborative research for water-related sciences, 3) fourteen new operational products and services dedicated to appointed end-users, 4) new business and knowledge to inform individual and collective decisions in line with the Europe's smart growth and environmental objectives. The presentation will discuss challenges, progress and opportunities with the open data strategy, based on the experiences from working both at a Governmental institute and being part of the global research community.

HyCAW: Hydrological Climate change Adaptation Wizard

NASA Astrophysics Data System (ADS)

Bagli, Stefano; Mazzoli, Paolo; Broccoli, Davide; Luzzi, Valerio

2016-04-01

Changes in temporal and total water availability due to hydrologic and climate change requires an efficient use of resources through the selection of the best adaptation options. HyCAW provides a novel service to users willing or needing to adapt to hydrological change, by turning available scientific information into a user friendly online wizard that lets to: • Evaluate the monthly reduction of water availability induced by climate change; • Select the best adaptation options and visualize the benefits in terms of water balance and cost reduction; • Quantify potential of water saving by improving of water use efficiency. The tool entails knowledge of the intra-annual distribution of available surface and groundwater flows at a site under present and future (climate change) scenarios. This information is extracted from long term scenario simulation by E-HYPE (European hydrological predictions for the environment) model from Swedish Meteorological and Hydrological Institute, to quantify the expected evolution in water availability (e.g. percent reduction of soil infiltration and aquifer recharge; relative seasonal shift of runoff from summer to winter in mountain areas; etc.). Users are requested to provide in input their actual water supply on a monthly basis, both from surface and groundwater sources. Appropriate decision trees and an embedded precompiled database of Water saving technology for different sectors (household, agriculture, industrial, tourisms) lead them to interactively identify good practices for water saving/recycling/harvesting that they may implement in their specific context. Thanks to this service, users are not required to have a detailed understanding neither of data nor of hydrological processes, but may benefit of scientific analysis directly for practical adaptation in a simple and user friendly way, effectively improving their adaptation capacity. The tool is being developed under a collaborative FP7 funded project called SWITCH-ON (EU FP7 project No 603587) coordinated by SMHI (http://water-switch-on.eu/) and online demo is available at www.gecosistema.com/switchon

How to handle multidisciplinary, multi-national and multi-sectoral projects

NASA Astrophysics Data System (ADS)

Reitz, Anja; Wallmann, Klaus; Visbeck, Martin

2016-04-01

Collaborative research projects funded by the European Commission are by nature multi-national. Often they bring together different scientific communities as the questions raised in EU project calls can typically only be addressed through the convergence of these previously separated disciplines in one research consortium. Some work programmes even necessitate to team up as different disciplines as natural sciences, social science, legal science and economic science. Examples for such multi- national, -disciplinary and - sectoral projects are the EU projects ECO2 (FP7, concluded) and AtlantOS (H2020). Project managers of such projects need to develop skills beyond the common technical and management skills namely go into the domain of partners and stakeholders psychology and be able to maintain different perspectives on communication and interaction needs regarding cultural-, discipline- and sectoral background. Accordingly, the project manager has besides his technical role as manager at least three further roles: that of a communicator, that of a mediator and that of a person convincing partners of the necessary and selling the project products to the stakeholders. As the typical project manager has not too much power and authority by his position he has to use the power of smart communication and persuasion to overcome potential dissension between disciplines, national reservation or potential conflicts regarding different sectoral views. Accordingly, the project manager of such a complex project would try to arrange the ideal working environment by considering cultural feel, the cooperation of disciplines, information and the control of resources. The way he develops such ideal working environment is by reflection of past, present and future experiences/needs.

ACTRIS aerosol vertical profile data and observations: potentiality and first examples of integrated studies with models

NASA Astrophysics Data System (ADS)

Mona, Lucia; Benedetti, Angela; D'Amico, Giuseppe; Myhre, Cathrine Lund; Schulz, Michael; Wandinger, Ulla; Laj, Paolo; Pappalardo, Gelsomina

2016-04-01

The ACTRIS-2 project, funded by Horizon 2020, addresses the scope of integrating state-of-the-art European ground-based stations for long term observations of aerosols, clouds and short lived gases, capitalizing on the work of FP7-ACTRIS. It aims at achieving the construction of a user-oriented RI, unique in the EU-RI landscape for providing 4-D integrated high-quality data from near-surface to high altitude (vertical profiles and total-column) which are relevant to climate and air-quality research. ACTRIS-2 develops and implements, in a large network of stations in Europe and beyond, observational protocols that permit the harmonization of collected data and their dissemination. ACTRIS secures provision and dissemination of a unique set of data and data-products that would not otherwise be available with the same level of quality and standardization. This results from a 10-year plus effort in constructing a research infrastructure capable of responding to community needs and requirements, and has been engaged since the start of the FP5 EU commission program. ACTRIS ensures compliance with reporting requirements (timing, format, traceability) defined by the major global observing networks. EARLINET (European Aerosol research Lidar NETwork), the aerosol vertical profiling component of ACTRIS, is providing since May 2000 vertical profiles of aerosol extinction and backscatter over Europe. A new structure of the EARLINET database has been designed in a more user oriented approach reporting new data products which are more effective for specific uses of different communities. In particular, a new era is starting with the Copernicus program during which the aerosol vertical profiling capability will be fundamental for assimilation and validation purposes. The new data products have been designed thanks to a strong link with EARLINET data users, first of all modeling and satellite communities, established since the beginning of EARLINET and re-enforced within ACTRIS2. The potentiality of the new EARLINET data products and first examples of integrated studies with models will be presented at the conference. Acknowledgments: ACTRIS2 Research Infrastructure Project is funded by the European Union's Horizon 2020 research and innovation programme under the grant agreement n. 654169 and previously under FP7 grant agreement n. 262254.

Changing pattern of landslide risk in Europe - The SafeLand project

NASA Astrophysics Data System (ADS)

Nadim, F.; Kalsnes, B. G.; SafeLand Research Consortium

2011-12-01

The changing pattern of landslide hazard and risk caused by climate change and changes in demography, the need to protect people and property, the reality for society in Europe to live with hazard and risk and the need to manage risk were the motives for the project SafeLand: "Living with landslide risk in Europe: Assessment, effects of global change, and risk management strategies." SafeLand is a large, integrating research project under the European Commission's 7th Framework Programme (FP7). It started on 1 May 2009 and will go on for 3 years, ending on 30 April 2012. There project involves 27 partners from 12 European countries, and has international collaborators and advisers from China, India, USA, Japan and Hong Kong. SafeLand also involves 25 End-Users from 11 countries. SafeLand is coordinated by the International Centre for Geohazards (ICG) at Norwegian Geotechnical Institute in Norway. Further information on the SafeLand project can be found at its web site http://www.safeland-fp7.eu/ . SafeLand is an ongoing project, which results will be finalized in 2012. This lecture summarizes the SafeLand's activities and achievements until November 2011. The main results achieved so far include: - Development and testing of several empirical methods for predicting the characteristics of threshold rainfall events for triggering of precipitation-induced landslides. - Identification of landslide hazard and risk hotspots by an objective, GIS-based analysis for Europe. The results show clearly where landslides pose the largest hazard in Europe and the objective approach allows a ranking of the countries by exposed area and population. - Different regional climate model simulations over Europe (from the EU FP6 project ENSEMBLES) at a spatial resolution of 25 x 25 km have been used to perform an extreme value analysis for trends in heavy precipitation events. In winter a general trend towards more heavy precipitation events across all analyzed regional climate model simulations is found. For summer, a slight increase of heavy precipitation in Northern Europe and a general decrease in southern Europe is found in all regional climate model simulations. - The prototype of a web-based "toolbox" of innovative and technically appropriate prevention and mitigation measures was developed. The toolbox does a preliminary assessment and ranking of up to 60 structural and non-structural landslide risk mitigation options. - Development of an empirical model for assessing the changes in landslide frequency (hazard) as a function of changes in the demography and population density. - Case histories and "hotspots" of European Land¬slides have been collected and documented. Data for 41 potential case study sites have been compiled and summarized. These comprise 39 sites in Europe located in Italy, France, Norway, Switzerland, Austria, Andorra, and Romania; as well as one site in Canada and one in India. Almost every type of landslide and every type of movement is represented in these sites. - Research on stakeholder workshops and participatory processes to involve the population exposed to landslide risk in the decision-making process for choosing the most appropriate risk mitigation measure(s).

Validation of the CME Geomagnetic forecast alerts under COMESEP alert system

NASA Astrophysics Data System (ADS)

Dumbovic, Mateja; Srivastava, Nandita; Khodia, Yamini; Vršnak, Bojan; Devos, Andy; Rodriguez, Luciano

2017-04-01

An automated space weather alert system has been developed under the EU FP7 project COMESEP (COronal Mass Ejections and Solar Energetic Particles: http://comesep.aeronomy.be) to forecast solar energetic particles (SEP) and coronal mass ejection (CME) risk levels at Earth. COMESEP alert system uses automated detection tool CACTus to detect potentially threatening CMEs, drag-based model (DBM) to predict their arrival and CME geo-effectiveness tool (CGFT) to predict their geomagnetic impact. Whenever CACTus detects a halo or partial halo CME and issues an alert, DBM calculates its arrival time at Earth and CGFT calculates its geomagnetic risk level. Geomagnetic risk level is calculated based on an estimation of the CME arrival probability and its likely geo-effectiveness, as well as an estimate of the geomagnetic-storm duration. We present the evaluation of the CME risk level forecast with COMESEP alert system based on a study of geo-effective CMEs observed during 2014. The validation of the forecast tool is done by comparing the forecasts with observations. In addition, we test the success rate of the automatic forecasts (without human intervention) against the forecasts with human intervention using advanced versions of DBM and CGFT (self standing tools available at Hvar Observatory website: http://oh.geof.unizg.hr). The results implicate that the success rate of the forecast is higher with human intervention and using more advanced tools. This work has received funding from the European Commission FP7 Project COMESEP (263252). We acknowledge the support of Croatian Science Foundation under the project 6212 „Solar and Stellar Variability".

A Climate Information Portal for Copernicus: a central portal for European climate services?

NASA Astrophysics Data System (ADS)

Juckes, Martin; Swart, Rob; Thysse, Peter; Som de Cerff, Wim; Groot, Annemarie; Bennett, Victoria; Costa, Luis; Lückenkötter, Johannes; Callaghan, Sarah

2015-04-01

The FP7 project "Climate Information Portal for Copernicus" (CLIPC) is developing a demonstration portal for the Copernicus Climate Change Service (C3S). This project is one of a suite of FP7 research activities which are administratively independent of Copernicus, focussed on creating the technical and scientific building blocks needed for the service. It is to be expected that at EGU 2015 there will be many presentations describing portals delivering new and innovative ranges of services. It would be unwise to seek to replace all this creative activity with a single portal -- instead CLIPC is designing a portal to make distributed resources more accessible through flexible discovery systems. CLIPC needs to deliver more than a directory of resources: resources need to be presented in common protocols so that users can access multiple datasets. More information about the project objectives is available at www.clipc.eu. The gulf between the climate science communities and the end user communities is a central challenge being addressed in the project. It is important to understand that there is significant diversity and multiple communication barriers within these two sets of communities as well as between them. The CLIPC services must presentation will provide a review of progress towards this ambitious goal, through a discussion of user requirements activities, an overview of the proposed architecture, work on assessing and adjusting model biasses, and a discussion of the climate impact indicators which will be provided through the portal. When looking at the usability of data for the various users, CLIPC will implement a set of services functioning as a "knowledge base" supplying information to users about the data, including definitions of terminology used, quality of datasets, versioning, and user annotations.

New approaches in human health risk assessment

PubMed Central

Abass, Khaled; Carlsen, Anders; Rautio, Arja

2016-01-01

Studies on the precise impact of environmental pollutants on human health are difficult to undertake and interpret, because many genetic and environmental factors influence health at the same time and to varying degrees. Our chapter in the AMAP report was based on new approaches to describe risks and future needs. In this paper, we will introduce the issues associated with risk assessment of single chemicals, and present suggestions for future studies as well as a summary of lessons learned during the health-related parts of the European Union-funded FP7 project ArcRisk (Arctic Health Risks: Impacts on health in the Arctic and Europe owing to climate-induced changes in contaminant cycling, 2009–2014; www.arcrisk.eu). PMID:27974141

Uncertainty of fast biological radiation dose assessment for emergency response scenarios.

PubMed

Ainsbury, Elizabeth A; Higueras, Manuel; Puig, Pedro; Einbeck, Jochen; Samaga, Daniel; Barquinero, Joan Francesc; Barrios, Lleonard; Brzozowska, Beata; Fattibene, Paola; Gregoire, Eric; Jaworska, Alicja; Lloyd, David; Oestreicher, Ursula; Romm, Horst; Rothkamm, Kai; Roy, Laurence; Sommer, Sylwester; Terzoudi, Georgia; Thierens, Hubert; Trompier, Francois; Vral, Anne; Woda, Clemens

2017-01-01

Reliable dose estimation is an important factor in appropriate dosimetric triage categorization of exposed individuals to support radiation emergency response. Following work done under the EU FP7 MULTIBIODOSE and RENEB projects, formal methods for defining uncertainties on biological dose estimates are compared using simulated and real data from recent exercises. The results demonstrate that a Bayesian method of uncertainty assessment is the most appropriate, even in the absence of detailed prior information. The relative accuracy and relevance of techniques for calculating uncertainty and combining assay results to produce single dose and uncertainty estimates is further discussed. Finally, it is demonstrated that whatever uncertainty estimation method is employed, ignoring the uncertainty on fast dose assessments can have an important impact on rapid biodosimetric categorization.

Automated dynamic feature tracking of RSLs on the Martian surface through HiRISE super-resolution restoration and 3D reconstruction techniques

NASA Astrophysics Data System (ADS)

Tao, Y.; Muller, J.-P.

2017-09-01

In this paper, we demonstrate novel Super-resolution restoration and 3D reconstruction tools developed within the EU FP7 projects and their applications to advanced dynamic feature tracking through HiRISE repeat stereo. We show an example with one of the RSL sites in the Palikir Crater took 8 repeat-pass 25cm HiRISE images from which a 5cm RSL-free SRR image is generated using GPT-SRR. Together with repeat 3D modelling of the same area, it allows us to overlay tracked dynamic features onto the reconstructed "original" surface, providing a much more comprehensive interpretation of the surface formation processes in 3D.

Radio-loud AGN through the eyes of 3XMM, WISE and FIRST/NVSS

NASA Astrophysics Data System (ADS)

Mingo, B.

2014-07-01

We present the results from a new radio-loud AGN sample, obtained through the cross-correlation between the 3XMM, WISE and FIRST/NVSS catalogues. The radio selection allows us to eliminate the restrictions traditionally associated with mid-IR and X-ray sample selections, and to explore the population of lower luminosity AGN, in which the host galaxy contribution is substantial. We investigate the correlations between radio, mid-IR and X-ray emission associated to both stellar and AGN activity, and whether they can be disentangled. This work has been carried out as part of the ARCHES project. ARCHES (Astronomical Resource Cross-matching for High Energy Studies), funded within the EU/FP7-Cooperation Space framework, is a project which aims to produce well-characterised multi-wavelength data for large samples of sources drawn from the 3XMM serendipitous source catalogue.

Active animal health surveillance in European Union Member States: gaps and opportunities.

PubMed

Bisdorff, B; Schauer, B; Taylor, N; Rodríguez-Prieto, V; Comin, A; Brouwer, A; Dórea, F; Drewe, J; Hoinville, L; Lindberg, A; Martinez Avilés, M; Martínez-López, B; Peyre, M; Pinto Ferreira, J; Rushton, J; VAN Schaik, G; Stärk, K D C; Staubach, C; Vicente-Rubiano, M; Witteveen, G; Pfeiffer, D; Häsler, B

2017-03-01

Animal health surveillance enables the detection and control of animal diseases including zoonoses. Under the EU-FP7 project RISKSUR, a survey was conducted in 11 EU Member States and Switzerland to describe active surveillance components in 2011 managed by the public or private sector and identify gaps and opportunities. Information was collected about hazard, target population, geographical focus, legal obligation, management, surveillance design, risk-based sampling, and multi-hazard surveillance. Two countries were excluded due to incompleteness of data. Most of the 664 components targeted cattle (26·7%), pigs (17·5%) or poultry (16·0%). The most common surveillance objectives were demonstrating freedom from disease (43·8%) and case detection (26·8%). Over half of components applied risk-based sampling (57·1%), but mainly focused on a single population stratum (targeted risk-based) rather than differentiating between risk levels of different strata (stratified risk-based). About a third of components were multi-hazard (37·3%). Both risk-based sampling and multi-hazard surveillance were used more frequently in privately funded components. The study identified several gaps (e.g. lack of systematic documentation, inconsistent application of terminology) and opportunities (e.g. stratified risk-based sampling). The greater flexibility provided by the new EU Animal Health Law means that systematic evaluation of surveillance alternatives will be required to optimize cost-effectiveness.

Energetic and Environmental Impacts Related to Transport and Assembling Processes in ABiogas Production Plant from Marine Macroalgae (FP7 Project BioWALK4Biofuels)

NASA Astrophysics Data System (ADS)

Cappelli, Andrea; Gigli, Emanuele; Muzi, Luca; Renda, Roberto; Simoni, Silvano

2010-01-01

GHG emissions, eutrophication and energy dependence are problems that the EU has to face in the near future. The BioWALK4Biofuels project aims to find a common response to these challenges, taking advantage of spontaneous biological processes: the growth of algae and anaerobic digestion of biomass. This project is being built thanks to European funding under the 7th Framework Programme. To evaluate the results obtained, a first LCA study was carried out that, as regards the data on infrastructure and on the assembly of the plant, refers to data supplied by manufacturers, while the study of algal growth was made on the basis of a model of cultivation that takes account of the aspects that most affect this key process among all the ones that cooperate in the whole plant. The electricity and heat produced through a co-generator fueled by biogas produced from algal biomass, according to this study, are responsible for GHG emissions reduced by 52% compared to traditional technologies. The biogas produced during the 4 years of the project allows the substitution of 85 tonnes of oil equivalent (toe).

Challenges and opportunities of multi-disciplinary, multi-national and multi-sectoral projects

NASA Astrophysics Data System (ADS)

Reitz, Anja; Hamann, Kristin

2017-04-01

Collaborative research projects e.g. funded or supported by the European Commission are by nature multi-national. Often EU calls bring together different scientific communities to jointly tackle challenges that can only be addressed through the convergence of previously separated disciplines in one research consortium. Some work programmes even necessitate to team up as different disciplines as natural sciences, social science, legal science and economic science. Examples for such multi- national, -disciplinary and - sectoral projects are the EU projects ECO2 (FP7, concluded), AtlantOS (H2020) and MiningImpact (JPI Oceans). Project managers of such projects need to develop skills beyond the common technical and management skills namely go into the domain of partners and stakeholders psychology and be able to maintain different perspectives on communication and interaction needs regarding cultural-, discipline- and sectoral background. Accordingly, the project manager has besides his or her technical role as manager at least three further roles: that of a communicator, that of a mediator and that of a person convincing partners of the necessary and selling the project products to the stakeholders. As the typical project manager has not too much power and authority by his or her position he or she has to use the power of smart communication and persuasion to overcome potential dissension between disciplines, national reservation or potential conflicts regarding different sectoral views. Accordingly, the project manager of such complex projects would try to arrange the ideal working environment by considering cultural feel, the cooperation of disciplines, information and the control of resources. The way he or she develops such ideal working environment is by reflection of past, present and future experiences/needs.

Ocean Data Interoperability Platform (ODIP): developing a common framework for marine data management on a global scale

NASA Astrophysics Data System (ADS)

Schaap, D.

2015-12-01

Europe, the USA, and Australia are making significant progress in facilitating the discovery, access and long term stewardship of ocean and marine data through the development, implementation, population and operation of national, regional or international distributed ocean and marine observing and data management infrastructures such as SeaDataNet, EMODnet, IOOS, R2R, and IMOS. All of these developments are resulting in the development of standards and services implemented and used by their regional communities. The Ocean Data Interoperability Platform (ODIP) project is supported by the EU FP7 Research Infrastructures programme, National Science Foundation (USA) and Australian government and has been initiated 1st October 2012. Recently the project has been continued as ODIP 2 for another 3 years with EU HORIZON 2020 funding. ODIP includes all the major organisations engaged in ocean data management in EU, US, and Australia. ODIP is also supported by the IOC-IODE, closely linking this activity with its Ocean Data Portal (ODP) and Ocean Data Standards Best Practices (ODSBP) projects. The ODIP platform aims to ease interoperability between the regional marine data management infrastructures. Therefore it facilitates an organised dialogue between the key infrastructure representatives by means of publishing best practice, organising a series of international workshops and fostering the development of common standards and interoperability solutions. These are evaluated and tested by means of prototype projects. The presentation will give further background on the ODIP projects and the latest information on the progress of three prototype projects addressing: establishing interoperability between the regional EU, USA and Australia data discovery and access services (SeaDataNet CDI, US NODC, and IMOS MCP) and contributing to the global GEOSS and IODE-ODP portals; establishing interoperability between cruise summary reporting systems in Europe, the USA and Australia for routine harvesting of cruise data for delivery via the Partnership for Observation of Global Oceans (POGO) global portal; establishing common standards for a Sensor Observation Service (SOS) for selected sensors installed on vessels and in real-time monitoring systems using sensor web enablement (SWE)

Ocean Data Interoperability Platform (ODIP): developing a common framework for marine data management on a global scale

NASA Astrophysics Data System (ADS)

Schaap, Dick M. A.; Glaves, Helen

2016-04-01

Europe, the USA, and Australia are making significant progress in facilitating the discovery, access and long term stewardship of ocean and marine data through the development, implementation, population and operation of national, regional or international distributed ocean and marine observing and data management infrastructures such as SeaDataNet, EMODnet, IOOS, R2R, and IMOS. All of these developments are resulting in the development of standards and services implemented and used by their regional communities. The Ocean Data Interoperability Platform (ODIP) project is supported by the EU FP7 Research Infrastructures programme, National Science Foundation (USA) and Australian government and has been initiated 1st October 2012. Recently the project has been continued as ODIP II for another 3 years with EU HORIZON 2020 funding. ODIP includes all the major organisations engaged in ocean data management in EU, US, and Australia. ODIP is also supported by the IOC-IODE, closely linking this activity with its Ocean Data Portal (ODP) and Ocean Data Standards Best Practices (ODSBP) projects. The ODIP platform aims to ease interoperability between the regional marine data management infrastructures. Therefore it facilitates an organised dialogue between the key infrastructure representatives by means of publishing best practice, organising a series of international workshops and fostering the development of common standards and interoperability solutions. These are evaluated and tested by means of prototype projects. The presentation will give further background on the ODIP projects and the latest information on the progress of three prototype projects addressing: 1. establishing interoperability between the regional EU, USA and Australia data discovery and access services (SeaDataNet CDI, US NODC, and IMOS MCP) and contributing to the global GEOSS and IODE-ODP portals; 2. establishing interoperability between cruise summary reporting systems in Europe, the USA and Australia for routine harvesting of cruise data for delivery via the Partnership for Observation of Global Oceans (POGO) global portal; 3. the establishment of common standards for a Sensor Observation Service (SOS) for selected sensors installed on vessels and in real-time monitoring systems using sensor web enablement (SWE)

220GHz wideband 3D imaging radar for concealed object detection technology development and phenomenology studies

NASA Astrophysics Data System (ADS)

Robertson, Duncan A.; Macfarlane, David G.; Bryllert, Tomas

2016-05-01

We present a 220 GHz 3D imaging `Pathfinder' radar developed within the EU FP7 project CONSORTIS (Concealed Object Stand-Off Real-Time Imaging for Security) which has been built to address two objectives: (i) to de-risk the radar hardware development and (ii) to enable the collection of phenomenology data with ~1 cm3 volumetric resolution. The radar combines a DDS-based chirp generator and self-mixing multiplier technology to achieve a 30 GHz bandwidth chirp with such high linearity that the raw point response is close to ideal and only requires minor nonlinearity compensation. The single transceiver is focused with a 30 cm lens mounted on a gimbal to acquire 3D volumetric images of static test targets and materials.

Multi-walled carbon nanotubes (NM401) induce ROS-mediated HPRT mutations in Chinese hamster lung fibroblasts

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rubio, Laura; El Yamani, Naouale; Kazimirova, Alena

Although there is an important set of data showing potential genotoxic effects of nanomaterials (NMs) at the DNA (comet assay) and chromosome (micronucleus test) levels, few studies have been conducted to analyze their potential mutagenic effects at gene level. We have determined the ability of multi-walled carbon nanotubes (MWCNT, NM401), to induce mutations in the HPRT gene in Chinese hamster lung (V79) fibroblasts. NM401, characterized in the EU NanoGenotox project, were further studied within the EU Framework Programme Seven (FP7) project NANoREG. From the proliferation assay data we selected a dose-range of 0.12 to 12 µg/cm{sup 2} At these rangemore » we have been able to observe significant cellular uptake of MWCNT by using transmission electron microscopy (TEM), as well as a concentration-dependent induction of intracellular reactive oxygen species. In addition, a clear concentration-dependent increase in the induction of HPRT mutations was also observed. Data support a potential genotoxic/ carcinogenic risk associated with MWCNT exposure. - Highlights: • MWCNT were tested in V79 cells. • Cellular uptake of MWCNT was detected using TEM. • Intracellular ROS induction was observed after MWCNT exposure. • MWCNT induced a concentration-dependent increase of HPRT mutations.« less

Implementation Strategies for Gender-Sensitive Public Health Practice: A European Workshop.

PubMed

Oertelt-Prigione, Sabine; Dalibert, Lucie; Verdonk, Petra; Stutz, Elisabeth Zemp; Klinge, Ineke

2017-11-01

Providing a robust scientific background for the focus on gender-sensitive public health and a systematic approach to its implementation. Within the FP7-EUGenMed project ( http://eugenmed.eu ) a workshop on sex and gender in public health was convened on February 2-3, 2015. The experts participated in moderated discussion rounds to (1) assemble available knowledge and (2) identify structural influences on practice implementation. The findings were summarized and analyzed in iterative rounds to define overarching strategies and principles. The participants discussed the rationale for implementing gender-sensitive public health and identified priorities and key stakeholders to engage in the process. Communication strategies and specific promotion strategies with distinct stakeholders were defined. A comprehensive list of gender-sensitive practices was established using the recently published taxonomy of the Expert Recommendations for Implementing Change (ERIC) project as a blueprint. A clearly defined implementation strategy should be mandated for all new projects in the field of gender-sensitive public health. Our tool can support researchers and practitioners with the analysis of current and past research as well as with the planning of new projects.

The Sternheimer-GW method and the spectral signatures of plasmonic polarons

NASA Astrophysics Data System (ADS)

Giustino, Feliciano

During the past three decades the GW method has emerged among the most promising electronic structure techniques for predictive calculations of quasiparticle band structures. In order to simplify the GW work-flow while at the same time improving the calculation accuracy, we developed the Sternheimer-GW method. In Sternheimer-GW both the screened Coulomb interaction and the electron Green's function are evaluated by using exclusively occupied Kohn-Sham states, as in density-functional perturbation theory. In this talk I will review the basics of Sternheimer-GW, and I will discuss two recent applications to semiconductors and superconductors. In the case of semiconductors we calculated complete energy- and momentum-resolved spectral functions by combining Sternheimer-GW with the cumulant expansion approach. This study revealed the existence of band structure replicas which arise from electron-plasmon interactions. In the case of superconductors we calculated the Coulomb pseudo-potential from first principles, and combined this approach with the Eliashberg theory of the superconducting critical temperature. This work was supported by the Leverhulme Trust (RL-2012-001), the European Research Council (EU FP7/ERC 239578), the UK Engineering and Physical Sciences Research Council (EP/J009857/1), and the Graphene Flagship (EU FP7/604391).

EU-FP7-iMARS: analysis of Mars multi-resolution images using auto-coregistration, data mining and crowd source techniques

NASA Astrophysics Data System (ADS)

Ivanov, Anton; Muller, Jan-Peter; Tao, Yu; Kim, Jung-Rack; Gwinner, Klaus; Van Gasselt, Stephan; Morley, Jeremy; Houghton, Robert; Bamford, Steven; Sidiropoulos, Panagiotis; Fanara, Lida; Waenlish, Marita; Walter, Sebastian; Steinkert, Ralf; Schreiner, Bjorn; Cantini, Federico; Wardlaw, Jessica; Sprinks, James; Giordano, Michele; Marsh, Stuart

2016-07-01

Understanding planetary atmosphere-surface and extra-terrestrial-surface formation processes within our Solar System is one of the fundamental goals of planetary science research. There has been a revolution in planetary surface observations over the last 15 years, especially in 3D imaging of surface shape. This has led to the ability to be able to overlay different epochs back in time to the mid 1970s, to examine time-varying changes, such as the recent discovery of mass movement, tracking inter-year seasonal changes and looking for occurrences of fresh craters. Within the EU FP-7 iMars project, UCL have developed a fully automated multi-resolution DTM processing chain, called the Co-registration ASP-Gotcha Optimised (CASP-GO), based on the open source NASA Ames Stereo Pipeline (ASP), which is being applied to the production of planetwide DTMs and ORIs (OrthoRectified Images) from CTX and HiRISE. Alongside the production of individual strip CTX & HiRISE DTMs & ORIs, DLR have processed HRSC mosaics of ORIs and DTMs for complete areas in a consistent manner using photogrammetric bundle block adjustment techniques. A novel automated co-registration and orthorectification chain has been developed and is being applied to level-1 EDR images taken by the 4 NASA orbital cameras since 1976 using the HRSC map products (both mosaics and orbital strips) as a map-base. The project has also included Mars Radar profiles from Mars Express and Mars Reconnaissance Orbiter missions. A webGIS has been developed for displaying this time sequence of imagery and a demonstration will be shown applied to one of the map-sheets. Automated quality control techniques are applied to screen for suitable images and these are extended to detect temporal changes in features on the surface such as mass movements, streaks, spiders, impact craters, CO2 geysers and Swiss Cheese terrain. These data mining techniques are then being employed within a citizen science project within the Zooniverse family to verify the results of these data mining techniques. Examples of data mining and its verification will be presented. We will present a software tool to ease access to co-registered MARSIS and SHARAD radargrams and geometry data such as probing point latitude and longitude and spacecraft altitude. Data are extracted from official ESA and NASA released data using self-developed python classes. Geometrical data and metadata are exposed as WFS layers using a QGIS server, which can be further integrated with other data. Radar geometry data will be available as a part of the iMars WebGIS framework and images will be available via PDS and PSA archives. Acknowledgements The research leading to these results has received funding from the European Union's Seventh Framework Programme (FP7/2007-2013) under iMars grant agreement n˚ 607379 as well as partial funding from the STFC "MSSL Consolidated Grant" ST/K000977/1.

Five Years of Research Into Technology-Enhanced Learning at the Faculty of Materials Science and Technology

NASA Astrophysics Data System (ADS)

Svetský, Štefan; Moravčík, Oliver; Rusková, Dagmar; Balog, Karol; Sakál, Peter; Tanuška, Pavol

2011-01-01

The article describes a five-year period of Technology Enhanced Learning (TEL) implementation at the Faculty of Materials Science and Technology (MTF) in Trnava. It is a part of the challenges put forward by the 7th Framework Programme (ICT research in FP7) focused on "how information and communication technologies can be used to support learning and teaching". The empirical research during the years 2006-2008 was focused on technology-driven support of teaching, i. e. the development of VLE (Virtual Learning Environment) and the development of database applications such as instruments developed simultaneously with the information support of the project, and tested and applied directly in the teaching of bachelor students. During this period, the MTF also participated in the administration of the FP7 KEPLER project proposal in the international consortium of 20 participants. In the following period of 2009-2010, the concept of educational activities automation systematically began to develop. Within this concept, the idea originated to develop a universal multi-purpose system BIKE based on the batch processing knowledge paradigm. This allowed to focus more on educational approach, i.e. TEL educational-driven and to finish the programming of the Internet application - network for feedback (communication between teachers and students). Thanks to this specialization, the results of applications in the teaching at MTF could gradually be presented at the international conferences focused on computer-enhanced engineering education. TEL was implemented at a detached workplace and four institutes involving more than 600 students-bachelors and teachers of technical subjects. Four study programmes were supported, including technical English language. Altogether, the results have been presented via 16 articles in five countries, including the EU level (IGIP-SEFI).

HAMLET -Human Model MATROSHKA for Radiation Exposure Determination of Astronauts -Current status and results

NASA Astrophysics Data System (ADS)

Reitz, Guenther; Berger, Thomas; Bilski, Pawel; Burmeister, Soenke; Labrenz, Johannes; Hager, Luke; Palfalvi, Jozsef K.; Hajek, Michael; Puchalska, Monika; Sihver, Lembit

The exploration of space as seen in specific projects from the European Space Agency (ESA) acts as groundwork for human long duration space missions. One of the main constraints for long duration human missions is radiation. The radiation load on astronauts and cosmonauts in space (as for the ISS) is a factor of 100 higher than the natural radiation on Earth and will further increase should humans travel to Mars. In preparation for long duration space missions it is important to evaluate the impact of space radiation in order to secure the safety of the astronauts and minimize their radiation risks. To determine the radiation risk on humans one has to measure the radiation doses to radiosensitive organs within the human body. One way to approach this is the ESA facility MATROSHKA (MTR), under the scientific and project lead of DLR. It is dedicated to determining the radiation load on astronauts within and outside the International Space Station (ISS), and was launched in January 2004. MTR is currently preparing for its fourth experimental phase inside the Japanese Experimental Module (JEM) in summer 2010. MTR, which mimics a human head and torso, is an anthropomorphic phantom containing over 6000 radiation detectors to determine the depth dose and organ dose distribution in the body. It is the largest international research initiative ever performed in the field of space dosimetry and combines the expertise of leading research institutions around the world, thereby generating a huge pool of data of potentially immense value for research. Aiming at optimal scientific exploitation, the FP7 project HAMLET aims to process and compile the data acquired individually by the participating laboratories of the MATROSHKA experiment. Based on experimental input from the MATROSHKA experiment phases as well as on radiation transport calculations, a three-dimensional model for the distribution of radiation dose in an astronaut's body will be built up. The scientific achievements contribute essentially to radiation risk estimations for future interplanetary space exploration by humans, putting them on a solid experimental and theoretical basis. The talk will give an overview of the current status of the MATROSHKA data evaluation and results and comparisons of the first three MTR experimental phases (MTR-1, 2A and 2B). The HAMLET project is funded by the European Commission under the EUs Seventh Frame-work Programme (FP7) under Project Nr: 218817 and coordinated by the German Aerospace Center (DLR) http://www-fp7-hamlet.eu

QI2S - Quick Image Interpretation System

NASA Astrophysics Data System (ADS)

Naghmouchi, Jamin; Aviely, Peleg; Ginosar, Ran; Ober, Giovanna; Bischoff, Ole; Nadler, Ron; Guiser, David; Citroen, Meira; Freddi, Riccardo; Berekovic, Mladen

2015-09-01

The evolution of the Earth Observation mission will be driven by many factors, and the deveploment of new processing paradigms to facilitate data downlink, handling and storage will be a key factor. Next generation EO satellites will generate a great amount of data at a very high data rate, both radar and optical. Real-time onboard processing can be the solution to reduce data downlink and management on ground. Radiometric, geometric, and atmospheric corrections of EO data as well as material/object detection in addition to the well-known needs for image compression and signal processing can be performed directly on board and the aim of QI2S project is to demonstrate this. QI2S, a concept prototype system for novel onboard image processing and image interpretation which has been designed, developed and validated in the framework of an EU FP7 project, targets these needs and makes a significant step towards exceeding current roadmaps of leading space agencies for future payload processors. The QI2S system features multiple chip components of the RC64, a novel rad-hard 64-core signal processing chip, which targets DSP performance of 75 GMACs (16bit), 150 GOPS and 38 single precision GFLOPS while dissipating less than 10 Watts. It integrates advanced DSP cores with a multibank shared memory and a hardware scheduler, also supporting DDR2/3 memory and twelve 3.125 Gbps full duplex high-speed serial links using SpaceFibre and other protocols. The processor is being developed within the European FP7 Framework Program and will be qualified to the highest space standards.

Acceleration, Transport, Forecasting and Impact of solar energetic particles in the framework of the 'HESPERIA' HORIZON 2020 project

NASA Astrophysics Data System (ADS)

Malandraki, Olga; Klein, Karl-Ludwig; Vainio, Rami; Agueda, Neus; Nunez, Marlon; Heber, Bernd; Buetikofer, Rolf; Sarlanis, Christos; Crosby, Norma

2017-04-01

High-energy solar energetic particles (SEPs) emitted from the Sun are a major space weather hazard motivating the development of predictive capabilities. In this work, the current state of knowledge on the origin and forecasting of SEP events will be reviewed. Subsequently, we will present the EU HORIZON2020 HESPERIA (High Energy Solar Particle Events foRecastIng and Analysis) project, its structure, its main scientific objectives and forecasting operational tools, as well as the added value to SEP research both from the observational as well as the SEP modelling perspective. The project addresses through multi-frequency observations and simulations the chain of processes from particle acceleration in the corona, particle transport in the magnetically complex corona and interplanetary space to the detection near 1 AU. Furthermore, publicly available software to invert neutron monitor observations of relativistic SEPs to physical parameters that can be compared with space-borne measurements at lower energies is provided for the first time by HESPERIA. In order to achieve these goals, HESPERIA is exploiting already available large datasets stored in databases such as the neutron monitor database (NMDB) and SEPServer that were developed under EU FP7 projects from 2008 to 2013. Forecasting results of the two novel SEP operational forecasting tools published via the consortium server of 'HESPERIA' will be presented, as well as some scientific key results on the acceleration, transport and impact on Earth of high-energy particles. Acknowledgement: This project has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No 637324.

Automated science target selection for future Mars rovers: A machine vision approach for the future ESA ExoMars 2018 rover mission

NASA Astrophysics Data System (ADS)

Tao, Yu; Muller, Jan-Peter

2013-04-01

The ESA ExoMars 2018 rover is planned to perform autonomous science target selection (ASTS) using the approaches described in [1]. However, the approaches shown to date have focused on coarse features rather than the identification of specific geomorphological units. These higher-level "geoobjects" can later be employed to perform intelligent reasoning or machine learning. In this work, we show the next stage in the ASTS through examples displaying the identification of bedding planes (not just linear features in rock-face images) and the identification and discrimination of rocks in a rock-strewn landscape (not just rocks). We initially detect the layers and rocks in 2D processing via morphological gradient detection [1] and graph cuts based segmentation [2] respectively. To take this further requires the retrieval of 3D point clouds and the combined processing of point clouds and images for reasoning about the scene. An example is the differentiation of rocks in rover images. This will depend on knowledge of range and range-order of features. We show demonstrations of these "geo-objects" using MER and MSL (released through the PDS) as well as data collected within the EU-PRoViScout project (http://proviscout.eu). An initial assessment will be performed of the automated "geo-objects" using the OpenSource StereoViewer developed within the EU-PRoViSG project (http://provisg.eu) which is released in sourceforge. In future, additional 3D measurement tools will be developed within the EU-FP7 PRoViDE2 project, which started on 1.1.13. References: [1] M. Woods, A. Shaw, D. Barnes, D. Price, D. Long, D. Pullan, (2009) "Autonomous Science for an ExoMars Rover-Like Mission", Journal of Field Robotics Special Issue: Special Issue on Space Robotics, Part II, Volume 26, Issue 4, pages 358-390. [2] J. Shi, J. Malik, (2000) "Normalized Cuts and Image Segmentation", IEEE Transactions on Pattern Analysis and Machine Intelligence, Volume 22. [3] D. Shin, and J.-P. Muller (2009), Stereo workstation for Mars rover image analysis, in EPSC (Europlanets), Potsdam, Germany, EPSC2009-390

A statistical estimation of Snow Water Equivalent coupling ground data and MODIS images

NASA Astrophysics Data System (ADS)

Bavera, D.; Bocchiola, D.; de Michele, C.

2007-12-01

The Snow Water Equivalent (SWE) is an important component of the hydrologic balance of mountain basins and snow fed areas in general. The total cumulated snow water equivalent at the end of the accumulation season represents the water availability at melt. Here, a statistical methodology to estimate the Snow Water Equivalent, at April 1st, is developed coupling ground data (snow depth and snow density measurements) and MODIS images. The methodology is applied to the Mallero river basin (about 320 km²) located in the Central Alps, northern Italy, where are available 11 snow gauges and a lot of sparse snow density measurements. The application covers 7 years from 2001 to 2007. The analysis has identified some problems in the MODIS information due to the cloud cover and misclassification for orographic shadow. The study is performed in the framework of AWARE (A tool for monitoring and forecasting Available WAter REsource in mountain environment) EU-project, a STREP Project in the VI F.P., GMES Initiative.

Algorithm theoretical baseline for formaldehyde retrievals from S5P TROPOMI and from the QA4ECV project

NASA Astrophysics Data System (ADS)

De Smedt, Isabelle; Theys, Nicolas; Yu, Huan; Danckaert, Thomas; Lerot, Christophe; Compernolle, Steven; Van Roozendael, Michel; Richter, Andreas; Hilboll, Andreas; Peters, Enno; Pedergnana, Mattia; Loyola, Diego; Beirle, Steffen; Wagner, Thomas; Eskes, Henk; van Geffen, Jos; Folkert Boersma, Klaas; Veefkind, Pepijn

2018-04-01

On board the Copernicus Sentinel-5 Precursor (S5P) platform, the TROPOspheric Monitoring Instrument (TROPOMI) is a double-channel, nadir-viewing grating spectrometer measuring solar back-scattered earthshine radiances in the ultraviolet, visible, near-infrared, and shortwave infrared with global daily coverage. In the ultraviolet range, its spectral resolution and radiometric performance are equivalent to those of its predecessor OMI, but its horizontal resolution at true nadir is improved by an order of magnitude. This paper introduces the formaldehyde (HCHO) tropospheric vertical column retrieval algorithm implemented in the S5P operational processor and comprehensively describes its various retrieval steps. Furthermore, algorithmic improvements developed in the framework of the EU FP7-project QA4ECV are described for future updates of the processor. Detailed error estimates are discussed in the light of Copernicus user requirements and needs for validation are highlighted. Finally, verification results based on the application of the algorithm to OMI measurements are presented, demonstrating the performances expected for TROPOMI.

Citizen Observatories: A Standards Based Architecture

NASA Astrophysics Data System (ADS)

Simonis, Ingo

2015-04-01

A number of large-scale research projects are currently under way exploring the various components of citizen observatories, e.g. CITI-SENSE (http://www.citi-sense.eu), Citclops (http://citclops.eu), COBWEB (http://cobwebproject.eu), OMNISCIENTIS (http://www.omniscientis.eu), and WeSenseIt (http://www.wesenseit.eu). Common to all projects is the motivation to develop a platform enabling effective participation by citizens in environmental projects, while considering important aspects such as security, privacy, long-term storage and availability, accessibility of raw and processed data and its proper integration into catalogues and international exchange and collaboration systems such as GEOSS or INSPIRE. This paper describes the software architecture implemented for setting up crowdsourcing campaigns using standardized components, interfaces, security features, and distribution capabilities. It illustrates the Citizen Observatory Toolkit, a software suite that allows defining crowdsourcing campaigns, to invite registered and unregistered participants to participate in crowdsourcing campaigns, and to analyze, process, and visualize raw and quality enhanced crowd sourcing data and derived products. The Citizen Observatory Toolkit is not a single software product. Instead, it is a framework of components that are built using internationally adopted standards wherever possible (e.g. OGC standards from Sensor Web Enablement, GeoPackage, and Web Mapping and Processing Services, as well as security and metadata/cataloguing standards), defines profiles of those standards where necessary (e.g. SWE O&M profile, SensorML profile), and implements design decisions based on the motivation to maximize interoperability and reusability of all components. The toolkit contains tools to set up, manage and maintain crowdsourcing campaigns, allows building on-demand apps optimized for the specific sampling focus, supports offline and online sampling modes using modern cell phones with built-in sensing technologies, automates the upload of the raw data, and handles conflation services to match quality requirements and analysis challenges. The strict implementation of all components using internationally adopted standards ensures maximal interoperability and reusability of all components. The Citizen Observatory Toolkit is currently developed as part of the COBWEB research project. COBWEB is partially funded by the European Programme FP7/2007-2013 under grant agreement n° 308513; part of the topic ENV.2012.6.5-1 "Developing community based environmental monitoring and information systems using innovative and novel earth observation applications.

New drought indices from the assimilation of satellite data

NASA Astrophysics Data System (ADS)

Calvet, Jean-Christophe; Barbu, Alina; Fairbairn, David

2016-04-01

The current agricultural drought indicators produced by Meteo-France are derived from digital simulations of soil moisture produced by the SURFEX modelling platform. In the framework of the IMAGINES European project, a research was conducted in order to assess the impact on the monitoring of agricultural droughts of the integration of satellite data into SURFEX. A data assimilation system was implemented to this end. It provides simulations of the biomass and leaf area index of straw cereals and grasslands over France. It is shown that these simulations can be improved through the assimilation of satellite products distributed in near-real-time by the Copernicus Global Land service (http://land.copernicus.eu/global/). Reference in situ observations of the agricultural yields show that using satellite data, a significant correlation between the maximum annual above-ground biomass simulated by SURFEX and the agricultural yield at the scale of administrative units (départements) can be achieved. Without satellite data, very low correlations are observed. It is also shown that new 10-day drought indicators, complementary to soil moisture, can be derived from the leaf area index and from the above-ground biomass of vegetation. These demonstration drought monitoring products for the 2008-2013 period are freely available on the project web site (http://fp7-imagines.eu/) for 45 administrative units for cereals and for 48 administrative units for grasslands.

EMSO: European multidisciplinary seafloor observatory

NASA Astrophysics Data System (ADS)

Favali, Paolo; Beranzoli, Laura

2009-04-01

EMSO has been identified by the ESFRI Report 2006 as one of the Research Infrastructures that European members and associated states are asked to develop in the next decades. It will be based on a European-scale network of multidisciplinary seafloor observatories from the Arctic to the Black Sea with the aim of long-term real-time monitoring of processes related to geosphere/biosphere/hydrosphere interactions. EMSO will enhance our understanding of processes, providing long time series data for the different phenomenon scales which constitute the new frontier for study of Earth interior, deep-sea biology and chemistry, and ocean processes. The development of an underwater network is based on past EU projects and is supported by several EU initiatives, such as the on-going ESONET-NoE, aimed at strengthening the ocean observatories' scientific and technological community. The EMSO development relies on the synergy between the scientific community and industry to improve European competitiveness with respect to countries such as USA, Canada and Japan. Within the FP7 Programme launched in 2006, a call for Preparatory Phase (PP) was issued in order to support the foundation of the legal and organisational entity in charge of building up and managing the infrastructure, and coordinating the financial effort among the countries. The EMSO-PP project, coordinated by the Italian INGV with participation by 11 institutions from as many European countries, started in April 2008 and will last four years.

Multi Criteria Evaluation Module for RiskChanges Spatial Decision Support System

NASA Astrophysics Data System (ADS)

Olyazadeh, Roya; Jaboyedoff, Michel; van Westen, Cees; Bakker, Wim

2015-04-01

Multi-Criteria Evaluation (MCE) module is one of the five modules of RiskChanges spatial decision support system. RiskChanges web-based platform aims to analyze changes in hydro-meteorological risk and provides tools for selecting the best risk reduction alternative. It is developed under CHANGES framework (changes-itn.eu) and INCREO project (increo-fp7.eu). MCE tool helps decision makers and spatial planners to evaluate, sort and rank the decision alternatives. The users can choose among different indicators that are defined within the system using Risk and Cost Benefit analysis results besides they can add their own indicators. Subsequently the system standardizes and prioritizes them. Finally, the best decision alternative is selected by using the weighted sum model (WSM). The Application of this work is to facilitate the effect of MCE for analyzing changing risk over the time under different scenarios and future years by adopting a group decision making into practice and comparing the results by numeric and graphical view within the system. We believe that this study helps decision-makers to achieve the best solution by expressing their preferences for strategies under future scenarios. Keywords: Multi-Criteria Evaluation, Spatial Decision Support System, Weighted Sum Model, Natural Hazard Risk Management

Ice Nucleating Particles around the world - a global review

NASA Astrophysics Data System (ADS)

Kanji, Zamin A.; Atkinson, James; Sierau, Berko; Lohmann, Ulrike

2017-04-01

In the atmosphere the formation of new ice particles at temperatures above -36 °C is due to a subset of aerosol called Ice Nucleating Particles (INP). However, the spatial and temporal evolution of such particles is poorly understood. Current modelling of INP is attempting to estimate the sources and transport of INP, but is hampered by the availability and convenience of INP observations. As part of the EU FP7 project impact of Biogenic versus Anthropogenic emissions on Clouds and Climate: towards a Holistic UnderStanding (BACCHUS), historical and contemporary observations of INP have been collated into a database (http://www.bacchus-env.eu/in/) and are reviewed here. Outside of Europe and North America the coverage of measurements is sparse, especially for modern day climate - in many areas the only measurements available are from the mid-20th century. As well as an overview of all the data in the database, correlations with several accompanying variables are presented. For example, immersion freezing INP seem to be negatively correlated with altitude, whereas CFDC based condensation freezing INP show no height correlation. An initial global parameterisation of INP concentrations taking into account freezing temperature and relative humidity for use in modelling is provided.

Effects of agricultural management on productivity, soil quality and climate change mitigation - evaluations within the EU Project (FP 7) CATCH-C

NASA Astrophysics Data System (ADS)

Spiegel, Heide; Schlatter, Norman; Haslmayr, Hans-Peter; Baumgarten, Andreas; ten Berge, Hein

2014-05-01

Soils are the main basis for the production of food and feed. Furthermore, the production of biomass for energy and material use is becoming increasingly important. Goals for an optimal management of agricultural soils are, on the one hand, the maintenance or improvement of soil quality and, on the other hand, high productivity and climate change mitigation (reduction of GHG emissions and C sequestration). Thus, the EU project CATCH-C aims to evaluate current management practices concerning these three goals based on indicators derived from long-term field experiments of the project partners and from literature data. A maximum of 72 indicators for productivity, soil quality and the potential for carbon storage in the soil and the reduction of greenhouse gas emissions were selected by the project partners. As indicators for productivity, crop yields are determined in almost all field trials. The content of soil organic carbon (SOC) is an indicator for chemical, physical and biological soil quality and was analysed in the topsoil in all field trials. Less data exist for SOC contents in the subsoil. An important physical soil quality indicator is the bulk density, however, it is not determined in all field trials of the project partners. Therefore, information on SOC stocks, with relevance to carbon storage and climate change mitigation, is not available in all field experiments. Other physical indicators, such as penetration resistance, runoff coefficient and soil losses are evaluated. Essential biological indicators are microbial biomass and the number and weight of earthworms, which have been tested in several field trials. The evaluation of all these indicators will help to select "best management practices" and to address trade-offs and synergies for all indicators under consideration of major European farm type zones. CATCH-C is funded within the 7th Framework Programme for Research, Technological Development and Demonstration, Theme 2 - Biotechnologies, Agriculture & Food. (Grant Agreement N° 289782).

Sharing Water-related Information to Tackle Changes in the Hydrosphere - for Operational Needs (SWITCH-ON)

NASA Astrophysics Data System (ADS)

Arheimer, Berit

2014-05-01

A recently started EU project (FP7 project No 603587) called SWITCH-ON will establish new infrastructure for water research in Europe. The overall goal of the project is to make use of open data, and add value to society by repurposing and refining data from various sources. SWITCH-ON will establish new forms of water research and facilitate the development of new products and services based on principles of sharing and community building. The basic for this work is a virtual water-science laboratory, which consists of open data, dedicated software tools and a set of protocols, hosted at the "SWITCH-ON water information" portal at http://water-switch-on.eu/. The laboratory will seamlessly integrate the open data with harmonised modelling tools and facilities the performance of virtual experiments of comparative science. Comparative science is a new form of research, which will advance science by contrasting water related processes in different environments and help understand complex processes in a more holistic way than individual studies The SWITCH-ON objectives are to use open data for implementing: 1) an innovative spatial information platform with open data tailored for direct water assessments, 2) an entirely new form of collaborative research for water-related sciences, 3) fourteen new operational products and services dedicated to appointed end-users, 4) new business and knowledge to inform individual and collective decisions in line with the Europe's smart growth and environmental objectives. The SWITCH-ON project will be one trigger in a contemporary global movement to better address environmental and societal challenges through openness and collaboration. The poster will present the project visions and achievements so far, and invite more research groups to use the virtual water-science laboratory.

High sensitivity test of the Pauli Exclusion Principle for electrons with X-ray spectroscopy (VIP2)

NASA Astrophysics Data System (ADS)

Marton, Johann; VIP2 Collaboration

2015-10-01

The Pauli Exclusion Principle (PEP) is one of the most fundamental rules in physics and it has various important consequences ranging from atomic and subatomic systems to the stability of matter and stellar objects like neutron stars. Due to many observations This rule must be valid to an extremely high degree and consequently no violations were found so far. On the other hand a simple explanation of PEP is still missing. Many experimental investigations based on different assumptions were performed to search for a tiny PEP violation in various systems. The experiment VIP2 at the Gran Sasso underground laboratory (LNGS of INFN) is designed to test the PEP for electrons with high sensitivity by searching for forbidden X-ray transitions in copper atoms. This experiment aims to improve the PEP violation limit obtained with our preceding experiment VIP by orders of magnitude. The experimental method, comparison of the VIP result with different PEP searches and the present status of the VIP2 experiment will be presented. We acknowledge the support from the: HadronPhysics FP6 (506078), HadronPhysics2 FP7 (227431), HadronPhysics3 (283286) projects, EU COST Action 1006 (Fundamental Problems in Quantum Physics) and the Austrian Science Fund (FWF).

An Optimised System for Generating Multi-Resolution Dtms Using NASA Mro Datasets

NASA Astrophysics Data System (ADS)

Tao, Y.; Muller, J.-P.; Sidiropoulos, P.; Veitch-Michaelis, J.; Yershov, V.

2016-06-01

Within the EU FP-7 iMars project, a fully automated multi-resolution DTM processing chain, called Co-registration ASP-Gotcha Optimised (CASP-GO) has been developed, based on the open source NASA Ames Stereo Pipeline (ASP). CASP-GO includes tiepoint based multi-resolution image co-registration and an adaptive least squares correlation-based sub-pixel refinement method called Gotcha. The implemented system guarantees global geo-referencing compliance with respect to HRSC (and thence to MOLA), provides refined stereo matching completeness and accuracy based on the ASP normalised cross-correlation. We summarise issues discovered from experimenting with the use of the open-source ASP DTM processing chain and introduce our new working solutions. These issues include global co-registration accuracy, de-noising, dealing with failure in matching, matching confidence estimation, outlier definition and rejection scheme, various DTM artefacts, uncertainty estimation, and quality-efficiency trade-offs.

The nature of micro CMEs within coronal holes

NASA Astrophysics Data System (ADS)

Bothmer, Volker; Nistico, Giuseppe; Zimbardo, Gaetano; Patsourakos, Spiros; Bosman, Eckhard

Whilst investigating the origin and characteristics of coronal jets and large-scale CMEs identi-fied in data from the SECCHI (Sun Earth Connection Coronal and Heliospheric Investigation) instrument suites on board the two STEREO satellites, we discovered transient events that originated in the low corona with a morphology resembling that of typical three-part struc-tured coronal mass ejections (CMEs). However, the CMEs occurred on considerably smaller spatial scales. In this presentation we show evidence for the existence of small-scale CMEs from inside coronal holes and present quantitative estimates of their speeds and masses. We interprete the origin and evolution of micro CMEs as a natural consequence of the emergence of small-scale magnetic bipoles related to the Sun's ever changing photospheric magnetic flux on various scales and their interactions with the ambient plasma and magnetic field. The analysis of CMEs is performed within the framework of the EU Erasmus and FP7 SOTERIA projects.

Power Electronics Design of a Solar Powered In-car Wireless Tag for Asset Tracking and Parking Applications

NASA Astrophysics Data System (ADS)

Zhu, D.; Henaut, J.; Beeby, S. P.

2014-11-01

This paper reports the design and testing of a power conditioning circuit for a solar powered in-car wireless tag for asset tracking and parking application. Existing long range asset tracking is based on the GSM/GPRS network, which requires expensive subscriptions. The EU FP7 project CEWITT aims at developing a credit card sized autonomous wireless tag with GNSS geo-positioning capabilities to ensure the integrity and cost effectiveness for parking applications. It was found in previous research that solar cells are the most suitable energy sources for this application. This study focused on the power electronics design for the wireless tag. A suitable solar cell was chosen for its high power density. Charging circuit, hysteresis control circuit and LDO were designed and integrated to meet the system requirement. Test results showed that charging efficiency of 80 % had been achieved.

Collecting data from a sensor network in a single-board computer

NASA Astrophysics Data System (ADS)

Casciati, F.; Casciati, S.; Chen, Z.-C.; Faravelli, L.; Vece, M.

2015-07-01

The EU-FP7 project SPARTACUS, currently in progress, sees the international cooperation of several partners toward the design and implementation of a satellite based asset tracking for supporting emergency management in crisis operations. Due to the emergency environment, one has to rely on a low power consumption wireless communication. Therefore, the communication hardware and software must be designed to match requirements which can only be foreseen at the level of more or less likely scenarios. The latter aspect suggests a deep use of a simulator (instead of a real network of sensors) to cover extreme situations. The former power consumption remark suggests the use of a minimal computer (Raspberry Pi) as data collector. In this paper, the results of a broad simulation campaign are reported in order to investigate the accuracy of the received data and the global power consumption for each of the considered scenarios.

Archeological treasures protection based on early forest wildfire multi-band imaging detection system

NASA Astrophysics Data System (ADS)

Gouverneur, B.; Verstockt, S.; Pauwels, E.; Han, J.; de Zeeuw, P. M.; Vermeiren, J.

2012-10-01

Various visible and infrared cameras have been tested for the early detection of wildfires to protect archeological treasures. This analysis was possible thanks to the EU Firesense project (FP7-244088). Although visible cameras are low cost and give good results during daytime for smoke detection, they fall short under bad visibility conditions. In order to improve the fire detection probability and reduce the false alarms, several infrared bands are tested ranging from the NIR to the LWIR. The SWIR and the LWIR band are helpful to locate the fire through smoke if there is a direct Line Of Sight. The Emphasis is also put on the physical and the electro-optical system modeling for forest fire detection at short and longer ranges. The fusion in three bands (Visible, SWIR, LWIR) is discussed at the pixel level for image enhancement and for fire detection.

Arctic tipping points in an Earth system perspective.

PubMed

Wassmann, Paul; Lenton, Timothy M

2012-02-01

We provide an introduction to the volume The Arctic in the Earth System perspective: the role of tipping points. The terms tipping point and tipping element are described and their role in current science, general debates, and the Arctic are elucidated. From a wider perspective, the volume focuses upon the role of humans in the Arctic component of the Earth system and in particular the envelope for human existence, the Arctic ecosystems. The Arctic climate tipping elements, the tipping elements in Arctic ecosystems and societies, and the challenges of governance and anticipation are illuminated through short summaries of eight publications that derive from the Arctic Frontiers conference in 2011 and the EU FP7 project Arctic Tipping Points. Then some ideas based upon resilience thinking are developed to show how wise system management could ease pressures on Arctic systems in order to keep them away from tipping points.

Data Assimilation Results from PLASMON

NASA Astrophysics Data System (ADS)

Jorgensen, A. M.; Lichtenberger, J.; Duffy, J.; Friedel, R. H.; Clilverd, M.; Heilig, B.; Vellante, M.; Manninen, J. K.; Raita, T.; Rodger, C. J.; Collier, A.; Reda, J.; Holzworth, R. H.; Ober, D. M.; Boudouridis, A.; Zesta, E.; Chi, P. J.

2013-12-01

VLF and magnetometer observations can be used to remotely sense the plasmasphere. VLF whistler waves can be used to measure the electron density and magnetic Field Line Resonance (FLR) measurements can be used to measure the mass density. In principle it is then possible to remotely map the plasmasphere with a network of ground-based stations which are also less expensive and more permanent than satellites. The PLASMON project, funded by the EU FP-7 program, is in the process of doing just this. A large number of ground-based observations will be input into a data assimilative framework which models the plasmasphere structure and dynamics. The data assimilation framework combines the Ensemble Kalman Filter with the Dynamic Global Core Plasma Model. In this presentation we will describe the plasmasphere model, the data assimilation approach that we have taken, PLASMON data and data assimilation results for specific events.

EU-FP7-iMARS: analysis of Mars multi-resolution images using auto-coregistration, data mining and crowd source techniques: A Status Report

NASA Astrophysics Data System (ADS)

Muller, Jan-Peter; Sidiropoulos, Panagiotis; Tao, Yu; Gwinner, Klaus; Willner, Konrad; Fanara, Lida; Waehlisch, Marita; Walter, Sebastian; Schreiner, Bjoern; Steikert, Ralf; Ivanov, Anton B.; Cantini, Federico; Wardlaw, Jessica; Sprinks, James Christopher; Giordano, Michele; Kim, Jungrack; Houghton, Robert; Bamford, Steven

2016-10-01

There has been a revolution in 3D surface imaging of Mars over the last 12 years with systematic stereoscopy from HRSC and the production for almost 50% of the Martian surface of DTMs and ORIs. The iMars project has been exploiting this unique set of 3D products as a basemap to co-register NASA imagery going back to the 1970s. DLR have produced 3D HRSC mosaic products for large regions with c. 100 individual strips/region (MC-11E/W). UCL have developed an automated processing chain for CTX and HiRISE 3D processing to densify this global HRSC dataset with DTMs down to 18m and 75cm respectively [1]. A fully Automated Co-Registration and Orthorectification (ACRO) system has been developed at UCL and applied to the production of around 8,000 images co-registered to a HRSC pixel (typically 12.5m) and orthorectified to HRSC DTMs of 50-150m spacing [2]. These images are viewable through an OGC-compliant webGIS developed at FUB including tools for viewing sequences over the same area [3]. Corresponding MARSIS and SHARAD data can be viewed through the QGIS plugin available [4]. An automated data mining system is being developed at UCL [5] for change detection to search and classify features in images going back to Viking Orbiter of IFoV ≤100m. In parallel, a citizen science project at Nottingham University [6] is defining training samples for classification of change features and eventually for verification of change [7]. Scientific applications include change mapping over the SPRC [8], mass movements near the North Pole [9]; dark streaks [10] CRISM mapping of mineralogy of dust in the SPRC "Swiss cheese" layers [11] and mapping of dune movement [12]. [1] Tao, Y. & J.-P. Muller LPSC16-2074; [2] Gwinner, K. et al. EPSC15-672; [3] van Gasselt, S. et al. EPSC14-693; [4] Ivanov, A. & Cantini, F. EPSC16; [5] Sidiropoulos, P. & J.-P. Muller EPSC16; [6] Sprinks et al. EPSC16; [7] Wardlaw et al. EPSC16; [8] Putri et al., EPSC16;[9] Fanara, L. et al. EPSC 16; [10] Schreiner, B. et al., EPSC16; [11] Campbell, J.et al., EPSC16;[12] Kim, J-R., et al., EPSC16 AcknowledgementsThis research has received funding from the EU's FP7 Programme under iMars 607379. Partial support is also provided from the STFC Grant ST/K000977/1

The NMDB collaboration

NASA Astrophysics Data System (ADS)

Steigies, C. T.

2015-12-01

Since the International Geophysical Year (IGY) in 1957-58 cosmic rays areroutinely measured by many ground-based Neutron Monitors (NM) around theworld. The World Data Center for Cosmic Rays (WDCCR) was established as apart of this activity and is providing a database of cosmic-ray neutronobservations in unified formats. However, that standard data comprises onlyof one hour averages, whereas most NM stations have been enhanced at the endof the 20th century to provide data in one minute resolution or even better.This data was only available on the web-sites of the institutes operatingthe station, and every station invented their own data format for thehigh-resolution measurements. There were some efforts to collect data fromseveral stations, to make this data available on FTP servers, however noneof these efforts could provide real-time data for all stations.The EU FP7 project NMDB (real-time database for high-resolution NeutronMonitor measurements, http://nmdb.eu) was funded by the European Commission,and a new database was set up by several Neutron Monitor stations in Europeand Asia to store high-resolution data and to provide access to the data inreal-time (i.e. less than five minute delay). By storing the measurements ina database, a standard format for the high-resolution measurements isenforced. This database is complementary to the WDCCR, as it does not (yet)provide all historical data, but the creation of this effort has spurred anew collaboration between Neutron Monitor scientists worldwide, (new)stations have gone online (again), new projects are building on the resultsof NMDB, new users outside of the Cosmic Ray community are starting to useNM data for new applications like soil moisture measurements using cosmicrays. These applications are facilitated by the easy access to the data withthe http://nest.nmdb.eu interface that offers access to all NMDB data forall users.

Characterisation of LSO:Tb scintillator films for high resolution X-ray imaging applications

NASA Astrophysics Data System (ADS)

Cecilia, A.; Rack, A.; Douissard, P.-A.; Martin, T.; Dos Santos Rolo, T.; Vagovič, P.; Pelliccia, D.; Couchaud, M.; Dupré, K.; Baumbach, T.

2011-05-01

Within the framework of an FP6 project (SCINTAX)1The Project SCINTAX is funded by the European Community (STRP 033 427), . we developed a new thin film single crystal scintillator for high resolution X-ray imaging based on a layer of modified LSO (Lu2SiO5) grown by liquid phase epitaxy (LPE) on a dedicated substrate. In this work we present the characterisation of the scintillating LSO films in terms of optical and scintillation properties as well as spatial resolution performances. The obtained results are discussed and compared with the performances of the thin scintillating films commonly used in synchrotron-based micro-imaging applications.

Comparative study on Climate Change Policies in the EU and China

NASA Astrophysics Data System (ADS)

Bray, M.; Han, D.

2012-04-01

Both the EU and China are among the largest CO2 emitters in the world; their climate actions and policies have profound impacts on global climate change and may influence the activities in other countries. Evidence of climate change has been observed across Europe and China. Despite the many differences between the two regions, the European Commission and Chinese government support climate change actions. The EU has three priority areas in climate change: 1) understanding, monitoring and predicting climate change and its impact; 2) providing tools to analyse the effectiveness, cost and benefits of different policy options for mitigating climate change and adapting to its impacts; 3) improving, demonstrating and deploying existing climate friendly technologies and developing the technologies of the future. China is very vulnerable to climate change, because of its vast population, fast economic development, and fragile ecological environment. The priority policies in China are: 1) Carbon Trading Policy; 2) Financing Loan Policy (Special Funds for Renewable Energy Development); 3) Energy Efficiency Labelling Policy; 4) Subsidy Policy. In addition, China has formulated the "Energy Conservation Law", "Renewable Energy Law", "Cleaner Production Promotion Law" and "Circular Economy Promotion Law". Under the present EU Framework Programme FP7 there is a large number of funded research activities linked to climate change research. Current climate change research projects concentrate on the carbon cycle, water quality and availability, climate change predictors, predicting future climate and understanding past climates. Climate change-related scientific and technological projects in China are mostly carried out through national scientific and technological research programs. Areas under investigation include projections and impact of global climate change, the future trends of living environment change in China, countermeasures and supporting technologies of global environment change, formation mechanism and prediction theory of major climate and weather disasters in China, technologies of efficient use of clean energy, energy conservation and improvement of energy efficiency, development and utilisation technology of renewable energy and new energy. The EU recognises that developing countries, such as China and India, need to strengthen their economies through industrialisation. However this needs to be achieved at the same time as protecting the environment and sustainable use of energy. The EU has committed itself to assisting developing countries to achieve their goals in four priority areas: 1) raising the policy profile of climate change; 2) support for adaption to climate change; 3) support for mitigation of climate change; and 4) capacity development. This comparative study is part of the EU funded SPRING project which seeks to understand and assess Chinese and European competencies, with the aim of facilitating greater cooperation in future climate and environment research.

EU-FP7-iMARS: Analysis of Mars Multi-Resolution Images Using Auto-Coregistration Data Mining and Crowd Source Techniques: Processed Results - a First Look

NASA Astrophysics Data System (ADS)

Muller, Jan-Peter; Tao, Yu; Sidiropoulos, Panagiotis; Gwinner, Klaus; Willner, Konrad; Fanara, Lida; Waehlisch, Marita; van Gasselt, Stephan; Walter, Sebastian; Steikert, Ralf; Schreiner, Bjoern; Ivanov, Anton; Cantini, Federico; Wardlaw, Jessica; Morley, Jeremy; Sprinks, James; Giordano, Michele; Marsh, Stuart; Kim, Jungrack; Houghton, Robert; Bamford, Steven

2016-06-01

Understanding planetary atmosphere-surface exchange and extra-terrestrial-surface formation processes within our Solar System is one of the fundamental goals of planetary science research. There has been a revolution in planetary surface observations over the last 15 years, especially in 3D imaging of surface shape. This has led to the ability to overlay image data and derived information from different epochs, back in time to the mid 1970s, to examine changes through time, such as the recent discovery of mass movement, tracking inter-year seasonal changes and looking for occurrences of fresh craters. Within the EU FP-7 iMars project, we have developed a fully automated multi-resolution DTM processing chain, called the Coregistration ASP-Gotcha Optimised (CASP-GO), based on the open source NASA Ames Stereo Pipeline (ASP) [Tao et al., this conference], which is being applied to the production of planetwide DTMs and ORIs (OrthoRectified Images) from CTX and HiRISE. Alongside the production of individual strip CTX & HiRISE DTMs & ORIs, DLR [Gwinner et al., 2015] have processed HRSC mosaics of ORIs and DTMs for complete areas in a consistent manner using photogrammetric bundle block adjustment techniques. A novel automated co-registration and orthorectification chain has been developed by [Sidiropoulos & Muller, this conference]. Using the HRSC map products (both mosaics and orbital strips) as a map-base it is being applied to many of the 400,000 level-1 EDR images taken by the 4 NASA orbital cameras. In particular, the NASA Viking Orbiter camera (VO), Mars Orbiter Camera (MOC), Context Camera (CTX) as well as the High Resolution Imaging Science Experiment (HiRISE) back to 1976. A webGIS has been developed [van Gasselt et al., this conference] for displaying this time sequence of imagery and will be demonstrated showing an example from one of the HRSC quadrangle map-sheets. Automated quality control [Sidiropoulos & Muller, 2015] techniques are applied to screen for suitable images and these are extended to detect temporal changes in features on the surface such as mass movements, streaks, spiders, impact craters, CO2 geysers and Swiss Cheese terrain. For result verification these data mining techniques are then being employed within a citizen science project within the Zooniverse family. Examples of data mining and its verification will be presented.

A Probabilistic Cell Tracking Algorithm

NASA Astrophysics Data System (ADS)

Steinacker, Reinhold; Mayer, Dieter; Leiding, Tina; Lexer, Annemarie; Umdasch, Sarah

2013-04-01

The research described below was carried out during the EU-Project Lolight - development of a low cost, novel and accurate lightning mapping and thunderstorm (supercell) tracking system. The Project aims to develop a small-scale tracking method to determine and nowcast characteristic trajectories and velocities of convective cells and cell complexes. The results of the algorithm will provide a higher accuracy than current locating systems distributed on a coarse scale. Input data for the developed algorithm are two temporally separated lightning density fields. Additionally a Monte Carlo method minimizing a cost function is utilizied which leads to a probabilistic forecast for the movement of thunderstorm cells. In the first step the correlation coefficients between the first and the second density field are computed. Hence, the first field is shifted by all shifting vectors which are physically allowed. The maximum length of each vector is determined by the maximum possible speed of thunderstorm cells and the difference in time for both density fields. To eliminate ambiguities in determination of directions and velocities, the so called Random Walker of the Monte Carlo process is used. Using this method a grid point is selected at random. Moreover, one vector out of all predefined shifting vectors is suggested - also at random but with a probability that is related to the correlation coefficient. If this exchange of shifting vectors reduces the cost function, the new direction and velocity are accepted. Otherwise it is discarded. This process is repeated until the change of cost functions falls below a defined threshold. The Monte Carlo run gives information about the percentage of accepted shifting vectors for all grid points. In the course of the forecast, amplifications of cell density are permitted. For this purpose, intensity changes between the investigated areas of both density fields are taken into account. Knowing the direction and speed of thunderstorm cells is important for nowcasting. Therefore, the presented method is based on IC discharges which account for most lightning discharges and occur minutes before the first CG discharge. The cell tracking algorithm will be used as part of the integrated LoLight system. The research leading to these results has received funding from the European Union's Seventh Framework Programme managed by REA-Research Executive Agency http://ec.europa.eu/research/rea ([FP7/2007-2013] [FP7/2007-2011]) under grant agreement n° [262200].

ESPAS: the European e-science platform to access near-Earth space data (Invited)

NASA Astrophysics Data System (ADS)

Belehaki, A.; Hapgood, M. A.; Ritschel, B.; Manola, N.

2013-12-01

The aim of ESPAS platform is to integrate heterogeneous data from the earth's thermosphere, ionosphere, plasmasphere and magnetosphere. ESPAS supports the systematic exploration of multipoint measurements from the near-Earth space through homogenised access to multi-instrument data. It provides access to more than 40 datasets: Cluster, EISCAT, GIRO, DIAS, SWACI, CHAMP, SuperDARN, FPI, magnetometers INGV, SGO, DTU, IMAGE, TGO, IMAGE/RPI, ACE, SOHO, PROBA2, NOAA/POES, etc. The concept of extensibility to new data sets is an important element in the ESPAS architecture. Within the first year of the project, the main components of the system have been developed, namely, the data model, the XML schemas for metadata exchange format, the ontology, the wrapper installed at the data nodes so that the main platform harvest the metadata, the main platform built on the D-NET framework and the GUI with its designed workflows. The first working prototype supports the search for datasets among a selected number of databases (i.e., EDAM, DIAS, Cluster, SWACI data). The next immediate step would be the implementation of search for characteristics within the datasets. For the second release we are planning to deploy tools for conjunctions between ground-space and space-space and for coincidences. For the final phase of the project the ESPAS infrastructure will be extensively tested through the application of several use cases, designed to serve the needs of the wide interdisciplinary users and producers communities, such as the ionospheric, thermospheric, magnetospheric, space weather and space climate communities, the geophysics community, the space communications engineering, HF users, satellite operators, navigation and surveillance systems, and space agencies. The final ESPAS platform is expected to be delivered in 2015. The abstract is submitted on behalf of the ESPAS-FP7EU team (http://www.espas-fp7.eu): Mike Hapgood, Anna Belehaki, Spiros Ventouras, Natalia Manola, Antonis Lebesis, Bruno Zolesi, Tatjana Gerzen, Ingemar Häggström, Anna Charisi, Ivan Galkin, Jurgen Watermann, Matthew Angling, Timo Asikainen, Alan Aylward, Henrike Barkmann, Peter Bergqvist, Andrew Bushell, Fabien Darrouzet, Dimitris Dialetis, Carl-Fredrik Enell, Daniel Heynderickx, Norbert Jakowski, Magnar Johnsen, Jean Lilensten, Ian McCrea, Kalevi Mursula, Bogdan Nicula, Michael Pezzopane, Viviane Pierrard, Bodo Reinisch, Bernd Ritschel, Luca Spogli, Iwona Stanislawska, Claudia Stolle, Eija Tanskanen, Ioanna Tsagouri, Esa Turunen, Thomas Ulich, Matthew Wild, Tim Yeoman

Solar system plasma Turbulence: Observations, inteRmittency and Multifractals

NASA Astrophysics Data System (ADS)

Echim, Marius M.

2016-04-01

The FP7 project STORM is funded by the European Commission to "add value to existing data bases through a more comprehensive interpretation". STORM targets plasma and magnetic field databases collected in the solar wind (Ulysses and also some planetary missions), planetary magnetospheres (Venus Express, Cluster, a few orbits from Cassini), cometary magnetosheaths (e.g. Haley from Giotto observations). The project applies the same package of analysis methods on geomagnetic field observations from ground and on derived indices (e.g. AE, AL, AU, SYM-H). The analysis strategy adopted in STORM is built on the principle of increasing complexity, from lower (like, e.g., the Power Spectral Density - PSD) to higher order analyses (the Probability Distribution Functions - PDFs, Structure Functions - SFs, Fractals and Multifractals - MFs). Therefore STORM targets not only the spectral behavior of turbulent fluctuations but also their topology and scale behavior inferred from advanced mathematical algorithms and geometrical-like analogs. STORM started in January 2013 and ended in December 2015. We will report on a selection of scientific and technical achievements and will highlight: (1) the radial evolution of solar wind turbulence and intermittency based on Ulysses data with some contributions from Venus Express and Cluster; (2) comparative study of fast and slow wind turbulence and intermittency at solar minimum; (3) comparative study of the planetary response (Venus and Earth magnetosheaths) to turbulent solar wind; (4) the critical behavior of geomagnetic fluctuations and indices; (5) an integrated library for non-linear analysis of time series that includes all the approaches adopted in STORM to investigate solar system plasma turbulence. STORM delivers an unprecedented volume of analysed data for turbulence. The project made indeed a systematic survey, orbit by orbit, of data available from ESA repositories and Principal Investigators and provides results ordered as a function of the targeted system (solar wind/magnetospheres/geomagnetic indices), solar cycle phase (minimum versus maximum), type of result (PSDs, PDFs, Multifractals). The results catalogues, available online from http://www.storm-fp7.eu, include 4094 PSD spectra, 9566 PDFs and 15633 multifractal spectra (from partition function and respectively Rank Ordered (ROMA) formalisms). These results are obtained at solar maximum (2001-2002, both in the solar wind and the terrestrial magnetosheath) and solar minimum (1997-1998 in the solar wind, 2007-2008 in the solar wind, Venus and Earth magnetosheath and selected regions of the magnetosphere). Research supported by the European Community's Seventh Framework Programme (FP7/2007-2013) under grant agreement no 313038/STORM.

HAMLET -Matroshka IIA and IIB experiments aboard the ISS: comparison of organ doses

NASA Astrophysics Data System (ADS)

Kato, Zoltan; Reitz, Guenther; Berger, Thomas; Bilski, Pawel; Hajek, Michael; Sihver, Lembit; Palfalvi, Jozsef K.; Hager, Luke; Burmeister, Soenke

The Matroshka experiments and the related FP7 HAMLET project aimed to study the dose burden of the cosmic rays in the organs of the crew working inside and outside the ISS. Two of the experiments will be discussed. They were performed in two different locations inside the ISS: during the Matroshka 2A (in 2006) the phantom was stored in the Russian Docking Module (Pirs), while during the Matroshka 2B (in 2007-08) it was inside the Russian Service Module (Zvezda). Both experiments were performed in the decreasing phase of the solar cycle. Solid state nuclear track detectors (SSNTD) were applied to investigate the dose contribution of the high LET radiation above ˜10 keV/µm. Two configurations of SSNTDs stacks were constructed: one for the exposure in the so called organ dose boxes (in the lung and kidney), another one for the skin dose measurements, embedded in the nomex poncho of the Phantom. In addition a reference package was placed outside the phantom. After exposure the detectors were transferred to the Earth for data evaluation. Short and long etching procedures were applied to distinguish the high and low LET particles, respectively. The particle tracks were evaluated by a semi automated image analyzer. Addi-tionally manual track parameter measurements were performed on very long tracks. As the result of measurements the LET spectra were deduced. Based on these spectra, the absorbed dose, the dose equivalent and the mean quality factor were calculated. The configuration of the stacks, the methods of the calibration and evaluation and finally the results will be presented and compared. The multiple etching and the combined evaluation method allowed to determine the fraction of the dose originated from HZE particles (Z>2 and range > major axis). Further on, data eval-uation was performed to separate the secondary particles (target fragments) from the primary particles. Although the number of high LET particles above a ˜80 keV/µm was found to be higher during the Matroshka 2B experiment than in the previous phase it was not possible to attribute this observation to the lower Sun activity in 2008, since the locations inside the ISS were different. The HAMLET project is funded by the European Commission under the EUs Seventh Frame-work Programme (FP7) under Project Nr: 218817 and coordinated by the German Aerospace Center (DLR) http://www-fp7-hamlet.eu

Screening and validation of EXTraS data products

NASA Astrophysics Data System (ADS)

Carpano, Stefania; Haberl, F.; De Luca, A.; Tiengo, A.: Israel, G.; Rodriguez, G.; Belfiore, A.; Rosen, S.; Read, A.; Wilms, J.; Kreikenbohm, A.; Law-Green, D.

2015-09-01

The EXTraS project (Exploring the X-ray Transient and variable Sky) is aimed at fullyexploring the serendipitous content of the XMM-Newton EPIC database in the timedomain. The project is funded within the EU/FP7-Cooperation Space framework and is carried out by a collaboration including INAF (Italy), IUSS (Italy), CNR/IMATI (Italy), University of Leicester (UK), MPE (Germany) and ECAP (Germany). The several tasks consist in characterise aperiodicvariability for all 3XMM sources, search for short-term periodic variability on hundreds of thousands sources, detect new transient sources that are missed by standard source detection and hence not belonging to the 3XMM catalogue, search for long term variability by measuring fluxes or upper limits for both pointed and slew observations, and finally perform multiwavelength characterisation andclassification. Screening and validation of the different products is essentially in order to reject flawed results, generated by the automatic pipelines. We present here the screening tool we developed in the form of a Graphical User Interface and our plans for a systematic screening of the different catalogues.

Use of consumer insight in the new product development process in the meat sector.

PubMed

Grunert, Klaus G; Verbeke, Wim; Kügler, Jens O; Saeed, Faiza; Scholderer, Joachim

2011-11-01

Successful new product development requires input from the market throughout the product development process, from identification of opportunities via screening of ideas, development of concepts, development of physical prototypes and to launch. Drawing on work done in the EU FP6 projects PROSAFEBEEF and Q-PORKCHAINS and a Danish project, all dealing with new product development in the meat sector, it is shown how the use of consumer insight techniques can a) support the identification of market opportunities, b) make sure that technologies applied are acceptable to consumers, c) aid the selection and optimisation of new product concepts and related communication, and d) be used to test product prototypes before final launch. Copyright © 2011 Elsevier Ltd. All rights reserved.

Studying aerodynamic drag for modeling the kinematical behavior of CMEs

NASA Astrophysics Data System (ADS)

Temmer, M.; Vrsnak, B.; Moestl, C.; Zic, T.; Veronig, A. M.; Rollett, T.

2013-12-01

With the SECCHI instrument suite aboard STEREO, coronal mass ejections (CMEs) can be observed from multiple vantage points during their entire propagation all the way from the Sun to 1 AU. The propagation behavior of CMEs in interplanetary space is mainly influenced by the ambient solar wind flow. CMEs that are faster than the ambient solar wind get decelerated, whereas slower ones are accelerated until the CME speed is finally adjusted to the solar wind speed. On a statistical basis, empirical models taking into account the drag force acting on CMEs, are able to describe the observed kinematical behaviors. For several well observed CME events we derive the kinematical evolution by combining remote sensing and in situ data. The observed kinematical behavior is compared to results from current empirical and numerical propagation models. For this we mainly use the drag based model DBM as well as the MHD model ENLIL. We aim to obtain the distance regime at which the solar wind drag force is dominating the CME propagation and quantify differences between different model results. This work has received funding from the FWF: V195-N16, and the European Commission FP7 Projects eHEROES (284461, www.eheroes.eu) and COMESEP (263252, www.comesep.eu).

In-service and pre-service teacher education in IBSE: The ESTABLISH approach

NASA Astrophysics Data System (ADS)

Ješková, Zuzana; Kireš, Marián; McLoughlin, Eilish; Finlayson, Odilla; Ottander, Christina; Ekborg, Margareta

2016-05-01

One of the main goals of the ESTABLISH 7fp project (available on line at http://www.establish-fp7.eu/) was the development and implementation of the professional development teacher education programmes (TEP) to support teachers in adopting inquiry-based strategies in their teaching. Within the project there was a model for in-service and pre-service teacher training in IBSE designed and implemented across 12 participating countries. The programme is based on 4 core elements and 4 additional elements that are built around the IBSE teaching units developed within the project. As accepted by ESTABLISH partners, all teacher training programmes include the minimum of the four elements, i.e. introduction to IBSE, industrial content knowledge, teacher as implementer and teacher as developer of IBSE teaching materials. There are also four additional elements designed in detail, i.e. ICT for IBSE, argumentation in the classroom, research and design projects for students, assessment of IBSE. These can be added to the programme optionally with regard to the level of teachers' IBSE skills and current situation in education and teachers' professional development within the country. This ESTABLISH model of TEP was followed in participating countries in order to change teachers' attitudes from traditional ways of teaching towards adopting inquiry strategies and their successful implementation in the classroom. Within the face-to-face workshops teachers experienced and developed their inquiry based teaching strategies using specifically developed materials. In addition, the e-platform has been developed to provide on-line support. This platform provides educators and teachers with all the necessary materials for the training and IBSE teaching units and other teaching materials for teachers' ongoing help. The teacher training programme was successfully implemented in Slovakia. There were two runs of teacher training workshops on IBSE already carried out. Moreover, the additional element ICT in IBSE was developed more deeply designing a separate teacher training course for it. The contribution discusses in more details the success and problems of implementation in the context of Slovak educational environment.

Empowerment in practice - insights from CITI-SENSE project in Ljubljana

NASA Astrophysics Data System (ADS)

Robinson, Johanna; Kocman, David; Smolnikar, Miha; Mohorčič, Miha; Horvat, Milena

2014-05-01

We present specifics of the citizen empowerment and crowd sourced citizen science conducted in Ljubljana, Slovenia, as one of the case study cities within the ongoing EU-project CITI-SENSE. CITI-SENSE addresses urban air quality and rests on three pillars: technological platforms for distributed monitoring; novel information and communication technologies; and citizen participation. In the project, empowerment initiatives are conducted, enabling citizens to participate in various aspects of urban air quality, both outdoor and indoor at schools affecting everyday life of societal groups. Each participating country runs its own citizen empowerment campaign adapting to local circumstances. In addition to Ljubljana, local campaigns have been initiated in Barcelona, Belgrade, Edinburgh, Haifa, Ljubljana, Oslo, Ostrava, Vienna and in Vitoria. Poor air quality has been recognized as an important factor affecting the quality of life, especially in urban environments. In Ljubljana specifically, the main air pollution sources are traffic-related emissions, individual house heating devices including increased use of coal and biomass in recent years, and to a limit extent industrial point sources and waste disposal sites. Air quality can be occasionally very poor due to specific climatic conditions owing partially to its location in a basin and on the marshes, resulting in a very complex circulation of air masses, temperature inversions and formation of urban heat island. By recognizing this, we established the main stakeholders in the city who are responsible for monitoring the quality of air in Ljubljana. Based on full stakeholder analysis we consider co-operation with local governmental- and non-governmental institutions with already established means of communications with citizens, as a tool for empowerment. Since we spend over 90% of our time indoors, the indoor air quality is of great importance. It is why the CITI-SENSE project empowerment initiatives also cover this aspect. In Ljubljana we have identified and are involving three schools; differing by location, house type and age of students. The project also gives children a unique approach to learning about air quality issues - by being involved. To evaluate the success of empowerment initiatives after a pilot phase, key performance indicators (KPI) were defined that will enable performance improvement for the full implementation phase of the project. Acknowledgements: CITI-SENSE is a Collaborative Project partly funded by the EU FP7-ENV-2012 under grant agreement no 308524. www.citi-sense.eu.

The QWeCI Project: seamlessly linking climate science to society

NASA Astrophysics Data System (ADS)

Morse, A. P.; Caminade, C.; Jones, A. E.; MacLeod, D.; Heath, A. E.

2012-04-01

The EU FP7 QWeCI project Quantifying Weather and Climate Impacts on health in developing countries (www.liv.ac.uk/qweci) has 13 partners with 7 of these in Africa. The geographical focus of the project is in Senegal, Ghana and Malawi. In all three countries the project has a strong scientific dissemination outlook as well as having field based surveillance programmes in Ghana and Senegal to understand more about the local parameters controlling the transmission of malaria and in Senegal of Rift Valley fever. The project has a strong and active climate science activity in using hindcasts of the new System 4 seasonal forecasting system at ECMWF; to further develop the use of monthly to seasonal forecasts from ensemble prediction systems; within project downscaling development; the assessment of decadal ensemble prediction systems; and the development and testing of vector borne disease models for malaria and Rift Valley fever. In parallel with the science programme the project has a large outreach activity involving regular communication and bi-lateral exchanges, science and decision maker focused workshops. In Malawi a long range WiFi network has been established for the dissemination of data. In Senegal where they is a concentration of partners and stakeholders the project is gaining a role as a catalyst for wider health and climate related activity within government departments and national research bodies along with the support and involvement of local communities. Within these wider community discussions we have interactive inputs from African and European scientists who are partners in the project. This paper will show highlights of the work completed so far and give an outline to future development and to encourage a wider user interaction from outside of the current project team and their direct collaborators.

Thirty years of European biotechnology programmes: from biomolecular engineering to the bioeconomy.

PubMed

Aguilar, Alfredo; Magnien, Etienne; Thomas, Daniel

2013-06-25

This article traces back thirty years of biotechnology research sponsored by the European Union (EU). It outlines the crucial role played by De Nettancourt, Goffeau and Van Hoeck to promote and prepare the first European programme on biotechnology (1982-1986) run by the European Commission. Following this first biotechnology programme, others followed until the current one, part of the seventh Framework Programme for Research, Technological Development and Demonstration (2007-2013) (FP7). Particular attention is given to the statutory role of the European institutions in the design and orientation of the successive biotechnology programmes, compared to the more informal-yet visionary-role of key individuals upstream to any legislative decision. Examples of success stories and of the role of the biotechnology programmes in addressing societal issues and industrial competitiveness are also presented. Finally, an outline of Horizon 2020, the successor of FP7, is described, together with the role of biotechnology in building the bioeconomy. Copyright © 2012 Elsevier B.V. All rights reserved.

Multilaboratory evaluation of 15 bioassays for (eco)toxicity screening and hazard ranking of engineered nanomaterials: FP7 project NANOVALID.

PubMed

Bondarenko, Olesja M; Heinlaan, Margit; Sihtmäe, Mariliis; Ivask, Angela; Kurvet, Imbi; Joonas, Elise; Jemec, Anita; Mannerström, Marika; Heinonen, Tuula; Rekulapelly, Rohit; Singh, Shashi; Zou, Jing; Pyykkö, Ilmari; Drobne, Damjana; Kahru, Anne

2016-11-01

Within EU FP7 project NANOVALID, the (eco)toxicity of 7 well-characterized engineered nanomaterials (NMs) was evaluated by 15 bioassays in 4 laboratories. The highest tested nominal concentration of NMs was 100 mg/l. The panel of the bioassays yielded the following toxicity order: Ag > ZnO > CuO > TiO2 > MWCNTs > SiO2 > Au. Ag, ZnO and CuO proved very toxic in the majority of assays, assumingly due to dissolution. The latter was supported by the parallel analysis of the toxicity of respective soluble metal salts. The most sensitive tests/species were Daphnia magna (towards Ag NMs, 24-h EC50 = 0.003 mg Ag/l), algae Raphidocelis subcapitata (ZnO and CuO, 72-h EC50 = 0.14 mg Zn/l and 0.7 mg Cu/l, respectively) and murine fibroblasts BALB/3T3 (CuO, 48-h EC50 = 0.7 mg Cu/l). MWCNTs showed toxicity only towards rat alveolar macrophages (EC50 = 15.3 mg/l) assumingly due to high aspect ratio and TiO2 towards R. subcapitata (EC50 = 6.8 mg Ti/l) due to agglomeration of TiO2 and entrapment of algal cells. Finally, we constructed a decision tree to select the bioassays for hazard ranking of NMs. For NM testing, we recommend a multitrophic suite of 4 in vitro (eco)toxicity assays: 48-h D. magna immobilization (OECD202), 72-h R. subcapitata growth inhibition (OECD201), 30-min Vibrio fischeri bioluminescence inhibition (ISO2010) and 48-h murine fibroblast BALB/3T3 neutral red uptake in vitro (OECD129) representing crustaceans, algae, bacteria and mammalian cells, respectively. Notably, our results showed that these assays, standardized for toxicity evaluation of "regular" chemicals, proved efficient also for shortlisting of hazardous NMs. Additional assays are recommended for immunotoxicity evaluation of high aspect ratio NMs (such as MWCNTs).

Multilaboratory evaluation of 15 bioassays for (eco)toxicity screening and hazard ranking of engineered nanomaterials: FP7 project NANOVALID

PubMed Central

Bondarenko, Olesja M.; Heinlaan, Margit; Sihtmäe, Mariliis; Ivask, Angela; Kurvet, Imbi; Joonas, Elise; Jemec, Anita; Mannerström, Marika; Heinonen, Tuula; Rekulapelly, Rohit; Singh, Shashi; Zou, Jing; Pyykkö, Ilmari; Drobne, Damjana; Kahru, Anne

2016-01-01

Abstract Within EU FP7 project NANOVALID, the (eco)toxicity of 7 well-characterized engineered nanomaterials (NMs) was evaluated by 15 bioassays in 4 laboratories. The highest tested nominal concentration of NMs was 100 mg/l. The panel of the bioassays yielded the following toxicity order: Ag > ZnO > CuO > TiO2 > MWCNTs > SiO2 > Au. Ag, ZnO and CuO proved very toxic in the majority of assays, assumingly due to dissolution. The latter was supported by the parallel analysis of the toxicity of respective soluble metal salts. The most sensitive tests/species were Daphnia magna (towards Ag NMs, 24-h EC50 = 0.003 mg Ag/l), algae Raphidocelis subcapitata (ZnO and CuO, 72-h EC50 = 0.14 mg Zn/l and 0.7 mg Cu/l, respectively) and murine fibroblasts BALB/3T3 (CuO, 48-h EC50 = 0.7 mg Cu/l). MWCNTs showed toxicity only towards rat alveolar macrophages (EC50 = 15.3 mg/l) assumingly due to high aspect ratio and TiO2 towards R. subcapitata (EC50 = 6.8 mg Ti/l) due to agglomeration of TiO2 and entrapment of algal cells. Finally, we constructed a decision tree to select the bioassays for hazard ranking of NMs. For NM testing, we recommend a multitrophic suite of 4 in vitro (eco)toxicity assays: 48-h D. magna immobilization (OECD202), 72-h R. subcapitata growth inhibition (OECD201), 30-min Vibrio fischeri bioluminescence inhibition (ISO2010) and 48-h murine fibroblast BALB/3T3 neutral red uptake in vitro (OECD129) representing crustaceans, algae, bacteria and mammalian cells, respectively. Notably, our results showed that these assays, standardized for toxicity evaluation of “regular” chemicals, proved efficient also for shortlisting of hazardous NMs. Additional assays are recommended for immunotoxicity evaluation of high aspect ratio NMs (such as MWCNTs). PMID:27259032

Impact of storms on coastlines: preparing for the future without forgetting the past? Examples from European coastlines using a Storm Impact Database

NASA Astrophysics Data System (ADS)

Ciavola, Paolo; Garnier, Emmanuel; Ferreira, Oscar; Spencer, Thomas; Armaroli, Clara

2017-04-01

Severe storms have historically affected many European coastlines but the impact of each storm has been evaluated in different ways in different countries, often using local socio-economic impact criteria (e.g. loss of lives and damage to properties). Although the Xynthia (2010) storm, Atlantic coast of France, was the largest coastal disaster of the last 50 years, similar events have previously impacted Europe. The 1953 storm surge in the southern North Sea, resulted in over 2000 deaths and extensive flooding and was the catalyst for post WWII improvements in flood defences and storm early warning systems. On a longer timescale, the very extreme storm of 1634 AD re-configured Wadden Sea coastlines, accompanied by thousands of deaths. Establishing patterns of coastal risk and vulnerability is greatly helped by the use of historical sources, as these allow the development of more complete time series of storm events and their impacts. The work to be presented was supported by the EU RISC-KIT (Resilience-Increasing Strategies for Coasts - toolKIT) Project. RISC-KIT (http://www.risckit.eu/np4/home.html) is a EU FP7 Collaborative project that has developed methods, tools and management approaches to reduce risk and increase resilience to low frequency, high-impact hydro-meteorological events in the coastal zone. These products will enhance forecasting, prediction and early warning capabilities, improve the assessment of long-term coastal risk and optimize the mix of prevention, mitigation and preparedness measures. We analyse historical large-scale events occurred from The Middle Ages to the 1960s at the case study sites of North Norfolk Coast (UK), the Charente-Maritime and Vendée coast (France), the Cinque Terre-Liguria (Italy), the Emilia-Romagna coast (Italy), and the Ria Formosa coast (Portugal). The work presented here uses a database of events built by the project, examining records for the last 300 years, including the characteristics of the storms as well as recorded losses. Finally, lessons learned will be presented, understanding the interaction between DRR elements such as prevention, resilience, mitigation and preparedness. The project's database is publicly available (http://risckit.cloudapp.net/risckit/#/)

A vision and strategy for the virtual physiological human in 2010 and beyond.

PubMed

Hunter, Peter; Coveney, Peter V; de Bono, Bernard; Diaz, Vanessa; Fenner, John; Frangi, Alejandro F; Harris, Peter; Hose, Rod; Kohl, Peter; Lawford, Pat; McCormack, Keith; Mendes, Miriam; Omholt, Stig; Quarteroni, Alfio; Skår, John; Tegner, Jesper; Randall Thomas, S; Tollis, Ioannis; Tsamardinos, Ioannis; van Beek, Johannes H G M; Viceconti, Marco

2010-06-13

European funding under framework 7 (FP7) for the virtual physiological human (VPH) project has been in place now for nearly 2 years. The VPH network of excellence (NoE) is helping in the development of common standards, open-source software, freely accessible data and model repositories, and various training and dissemination activities for the project. It is also helping to coordinate the many clinically targeted projects that have been funded under the FP7 calls. An initial vision for the VPH was defined by framework 6 strategy for a European physiome (STEP) project in 2006. It is now time to assess the accomplishments of the last 2 years and update the STEP vision for the VPH. We consider the biomedical science, healthcare and information and communications technology challenges facing the project and we propose the VPH Institute as a means of sustaining the vision of VPH beyond the time frame of the NoE.

A vision and strategy for the virtual physiological human in 2010 and beyond

PubMed Central

Hunter, Peter; Coveney, Peter V.; de Bono, Bernard; Diaz, Vanessa; Fenner, John; Frangi, Alejandro F.; Harris, Peter; Hose, Rod; Kohl, Peter; Lawford, Pat; McCormack, Keith; Mendes, Miriam; Omholt, Stig; Quarteroni, Alfio; Skår, John; Tegner, Jesper; Randall Thomas, S.; Tollis, Ioannis; Tsamardinos, Ioannis; van Beek, Johannes H. G. M.; Viceconti, Marco

2010-01-01

European funding under framework 7 (FP7) for the virtual physiological human (VPH) project has been in place now for nearly 2 years. The VPH network of excellence (NoE) is helping in the development of common standards, open-source software, freely accessible data and model repositories, and various training and dissemination activities for the project. It is also helping to coordinate the many clinically targeted projects that have been funded under the FP7 calls. An initial vision for the VPH was defined by framework 6 strategy for a European physiome (STEP) project in 2006. It is now time to assess the accomplishments of the last 2 years and update the STEP vision for the VPH. We consider the biomedical science, healthcare and information and communications technology challenges facing the project and we propose the VPH Institute as a means of sustaining the vision of VPH beyond the time frame of the NoE. PMID:20439264

On the use of harmonized HCHO and NO2 MAXDOAS measurements for the validation of GOME-2 and OMI satellite sensors

NASA Astrophysics Data System (ADS)

Pinardi, Gaia; Hendrick, François; Gielen, Clio; Van Roozendael, Michel; De Smedt, Isabelle; Lambert, Jean-Christopher; Granville, José; Compernolle, Steven; Richter, Andreas; Peters, Enno; Piters, Ankie; Wagner, Thomas; Wang, Yang; Drosoglou, Theano; Bais, Alkis; Wang, Shanshan; Saiz-Lopez, Alfonso

2017-04-01

During the last decade, the MAXDOAS technique has been increasingly recognized as a source of Fiducial Reference Measurements (FRM) suitable for the validation of satellite nadir observations of species relevant for climate and air quality like NO2 and HCHO. As part of the EU FP7 QA4ECV (Quality Assurance for Essential Climate Variables; see http://www.qa4ecv.eu/) project, efforts have been recently made to harmonize a network of a dozen of MAXDOAS spectrometers in view of their use to assess the quality of satellite climate data records generated within the same project. Harmonization tasks have addressed both retrieval steps involved in MAXDOAS retrievals, i.e. the DOAS spectral fit providing the differential slant column densities (DSCDs) and the conversion of the retrieved DSCDs into vertical profiles and/or vertical column densities (VCDs). In this work, we illustrate the successive harmonization steps and present the resulting QA4ECV MAXDOAS database v2. The approach adopted for the conversion of slant to vertical columns is based on a simplified look-up-table approach. The strength and limitation of this approach are discussed using reference data retrieved using an optimal estimation scheme. The QA4ECV MAXDOAS database is then used to validate satellite data sets of NO2 and HCHO columns derived from the Aura/OMI and MetOp/GOME-2 sensors. The methodology of comparison, which is also a subject of the QA4ECV project, is reviewed with respect to co-location criteria, impact of vertical and horizontal smoothing and representativeness of validation sites. We conclude by assessing the current strengths and limitations of the existing MAXDOAS datasets for NO2 and HCHO satellite validation.

CardioScape mapping the cardiovascular funding landscape in Europe.

PubMed

Pries, Axel Radlach; Naoum, Anastasia; Habazettl, Helmut; Dunkel, Mathias; Preissner, Robert; Coats, Caroline J; Tornada, Ana; Orso, Francesco; Van de Werf, Frans; Wood, David A

2017-04-25

The burden of cardiovascular disease is increasing worldwide, which has to be reflected by cardiovascular (CV) research in Europe. CardioScape, a FP7 funded project initiated by the European Society of Cardiology (ESC), identified where CV research is performed, how it is funded and by whom. It could be transformed into an on-line and up-to-date resource of great relevance for researchers, funding bodies and policymakers and could be a role model for mapping CV research funding in Europe and beyond. Relevant funding bodies in 28 European Union (EU) countries were identified by a multistep process involving experts in each country. Projects above a funding threshold of 100 k€ during the period 2010-2012 were included using a standard questionnaire. Results were classified by experts and an adaptive text analysis software to a CV-research taxonomy, integrating existing schemes from ESC journals and congresses. An on-line query portal was set up to allow different users to interrogate the database according to their specific viewpoints. CV-research funding varies strongly between different nations with the EU providing 37% of total available project funding and clear geographical gradients exist. Data allow in depth comparison of funding for different research areas and led to a number of recommendations by the consortium. CardioScape can support CV research by aiding researchers, funding agencies and policy makers in their strategic decisions thus improving research quality if CardioScape strategy and technology becomes the basis of a continuously updated and expanded European wide publicly accessible database. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2017. For permissions, please email: journals.permissions@oup.com.

CBM Collaboration

NASA Astrophysics Data System (ADS)

Ablyazimov, T.; Abuhoza, A.; Adak, R.; Adamczewski-Musch, J.; Adamczyk, M.; Aggarwal, M. M.; Ahammed, Z.; Ahmad, F.; Ahmad, N.; Ahmad, S.; Akindinov, A.; Akishin, P.; Akishina, E.; Akishina, T.; Akishina, V.; Al-Turany, M.; Alexandrov, E.; Alexandrov, I.; Amar-Youcef, S.; Anđelić, M.; Andreeva, O.; Andrei, C.; Andronic, A.; Anisimov, Yu.; Appelshäuser, H.; Arend, A.; Argintaru, D.; Atkin, E.; Avdeev, S.; Averbeck, R.; Azmi, M. D.; Baban, V.; Bach, M.; Badura, E.; Baginyan, S.; Balle, T.; Balog, T.; Bandyopadhyay, S.; Banerjee, P.; Baranova, N.; Barczyk, T.; Bartoş, D.; Bashir, S.; Basrak, Z.; Baszczyk, M.; Batenkov, O.; Baublis, V.; Baumann, C.; Baznat, M.; Becker, K.-H.; Bel, T.; Belogurov, S.; Bendarouach, J.; Berceanu, I.; Bercuci, A.; Berdermann, E.; Berdnikov, A.; Berdnikov, Y.; Berendes, R.; Bergmann, C.; Bertini, D.; Bertini, O.; Beşliu, C.; Bezshyyko, O.; Bhaduri, P. P.; Bhasin, A.; Bhati, A. K.; Bhattacharjee, B.; Bhattacharyya, A.; Bhattacharyya, T. K.; Biswas, S.; Blau, D.; Blume, C.; Bocharov, Yu.; Böttger, S.; Borysova, M.; Breitner, T.; Brüning, U.; Brzychczyk, J.; Bubak, A.; Büsching, H.; Bychkov, A.; Byszuk, A.; Cai, Xu; Cãlin, M.; Cao, Ping; Čaplar, R.; Caragheorgheopol, G.; Carević, I.; Cătănescu, V.; Chakrabarti, A.; Chatterji, S.; Chattopadhyay, Sanatan; Chattopadhyay, Subhasis; Chen, Hongfang; Cheng, Jianping; Chepurnov, V.; Chernenko, S.; Chernogorov, A.; Choi, Kyung-Eon; Ciobanu, M. I.; Claus, G.; Constantin, F.; Covlea, V.; Csanád, M.; D'Ascenzo, N.; Das, S.; Davkov, K.; Davkov, V.; de Cuveland, J.; Debnath, B.; Dementiev, D.; Deng, Zhi; Deppe, H.; Deppner, I.; Derenovskaya, O.; Deveaux, C. A.; Deveaux, M.; Dey, K.; Dey, M.; Dillenseger, P.; Dobyrn, V.; Doering, D.; Dorokhov, A.; Drozd, A.; Dubey, A. K.; Dubnichka, S.; Dubnichkova, A.; Dürr, M.; Dulinski, W.; Dutka, L.; Dželalija, M.; Emschermann, D.; Engel, H.; Eremin, V.; Eşanu, T.; Eschke, J.; Eschweiler, D.; Eum, Jongsik; Fan, Huanhuan; Fateev, O.; Filozova, I.; Finogeev, D.; Fischer, P.; Flemming, H.; Frankenfeld, U.; Friese, V.; Friske, E.; Fröhlich, I.; Frühauf, J.; Fülöp, Á.; Gajda, J.; Galatyuk, T.; Galkin, A.; Galkin, V.; Gangopadhyay, G.; García Chávez, C.; Gašparić, I.; Gebelein, J.; Ghosh, P.; Ghosh, S. K.; Goffe, M.; Golinka-Bezshyyko, L.; Golovatyuk, V.; Golovnya, S.; Golovtsov, V.; Golubeva, M.; Golubkov, D.; Gómez Ramírez, A.; Gorbunov, S.; Gorokhov, S.; Gottschalk, D.; Gryboś, P.; Grzeszczuk, A.; Guber, F.; Gudima, K.; Gupta, A.; Gusakov, Yu.; Haldar, A.; Haldar, S.; Hartmann, H.; Hehner, J.; Heidel, K.; Heine, N.; Hellbär, E.; Herghelegiu, A.; Herrmann, N.; Heß, B.; Heuser, J. M.; Himmi, A.; Höhne, C.; Holzmann, R.; Huang, Guangming; Huang, Xinjie; Hutsch, J.; Hutter, D.; Iakovleva, E.; Ierusalimov, A.; Ilgenfritz, E.-M.; Irfan, M.; Ivanov, M.; Ivanov, Valery; Ivanov, Victor; Ivanov, Vladimir; Ivashkin, A.; Jaaskelainen, K.; Jahan, H.; Jain, V.; Jakovlev, V.; Janson, T.; Jipa, A.; Kadenko, I.; Kämpfer, B.; Kalcher, S.; Kalinin, V.; Kampert, K.-H.; Kang, Tae Im; Kaptur, E.; Karabowicz, R.; Karavichev, O.; Karavicheva, T.; Karmanov, D.; Karnaukhov, V.; Karpechev, E.; Kasiński, K.; Kasprowicz, G.; Kaur, M.; Kazantsev, A.; Kebschull, U.; Kekelidze, G.; Khan, M. M.; Khan, S. A.; Khanzadeev, A.; Khasanov, F.; Khvorostukhin, A.; Kirakosyan, V.; Kirejczyk, M.; Kiryakov, A.; Kiš, M.; Kisel, I.; Kisel, P.; Kiselev, S.; Kiss, A.; Kiss, T.; Klaus, P.; Kłeczek, R.; Klein-Bösing, Ch.; Kleipa, V.; Kmon, P.; Koch, K.; Kochenda, L.; Koczoń, P.; König, W.; Kohn, M.; Kolb, B. W.; Kolosova, A.; Komkov, B.; Kopfer, J. M.; Korolev, M.; Korolko, I.; Kotte, R.; Kotynia, A.; Kovalchuk, A.; Kowalski, S.; Koziel, M.; Kozlov, G.; Kravtsov, P.; Krebs, E.; Kreidl, C.; Kresan, D.; Kretschmar, G.; Kretz, M.; Krieger, M.; Kryshen, E.; Kucewicz, W.; Kudin, L.; Kugler, A.; Kulakov, I.; Kunkel, J.; Kurepin, A.; Kurilkin, P.; Kushpil, V.; Kyva, V.; Ladygin, V.; Lara, C.; Larionov, P.; Laso Garcia, A.; Lavrik, E.; Lazanu, I.; Lebedev, A.; Lebedev, S.; Lebedeva, E.; Lehnert, J.; Lehrbach, J.; Lemke, F.; Li, Cheng; Li, Jin; Li, Qiyan; Li, Yuanjing; Li, Yulan; Lindenstruth, V.; Linev, S.; Linnik, B.; Litvinenko, E.; Liu, Feng; Lobanov, I.; Lobanova, E.; Löchner, S.; Loizeau, P.-A.; Lucio Martínez, J. A.; Lymanets, A.; Maevskaya, A.; Mahajan, S.; Mahapatra, D. P.; Mahmoud, T.; Maj, P.; Majka, Z.; Malakhov, A.; Malankin, E.; Malkevich, D.; Malyatina, O.; Malygina, H.; Mandal, S.; Manko, V.; Manz, S.; Marin, V.; Marin Garcia, A. M.; Markert, J.; Masciocchi, S.; Matulewicz, T.; Merkin, M.; Mialkovski, V.; Michel, J.; Miftakhov, N.; Mikhailov, K.; Mikhaylov, V.; Milanović, B.; Militsija, V.; Mir, M. F.; Miskowiec, D.; Morhardt, T.; Müller, W. F. J.; Müntz, C.; Murin, Yu.; Najman, R.; Naumann, L.; Nayak, T.; Nedosekin, A.; Neumann, B.; Niebur, W.; Nikulin, V.; Normanov, D.; Nüssle, M.; Oancea, A.; Oh, Kunsu; Onishchuk, Y.; Osipov, D.; Ososkov, G.; Ossetski, D.; Otfinowski, P.; Ovcharenko, E.; Pal, S.; Panasenko, I.; Panda, N. R.; Parzhitskiy, S.; Pauly, C.; Peng, Haiping; Peric, I.; Peshekhonov, D.; Peshekhonov, V.; Petráček, V.; Petriş, M.; Petrovici, A.; Petrovici, M.; Petrovskiy, A.; Petukhov, O.; Piasecki, K.; Pieper, J.; Pietraszko, J.; Płaneta, R.; Plekhanov, E.; Plotnikov, V.; Plujko, V.; Pluta, J.; Poliakov, V.; Polozov, P.; Pop, A.; Popov, V.; Pospisil, V.; Potukuchi, B. V. K. S.; Pouryamout, J.; Poźniak, K.; Prakash, A.; Prokudin, M.; Pshenichnov, I.; Pugach, M.; Pugatch, V.; Querchfeld, S.; Radulescu, L.; Raha, S.; Raja, W.; Rami, F.; Raniwala, R.; Raniwala, S.; Raportirenko, A.; Rautenberg, J.; Rauza, J.; Ray, R.; Razin, S.; Reichelt, P.; Reinecke, S.; Reshetin, A.; Ristea, C.; Ristea, O.; Roether, F.; Romaniuk, R.; Rost, A.; Rostchin, E.; Rostovtseva, I.; Roy, A.; Rożynek, J.; Ryabov, Yu.; Rykalin, V.; Sadovsky, A.; Sadovsky, S.; Sahoo, R.; Sahu, P. K.; Saini, J.; Samanta, S.; Sambyal, S. S.; Samsonov, V.; Sánchez Rosado, J.; Sau, S.; Saveliev, V.; Schatral, S.; Schiaua, C.; Schmidt, C. J.; Schmidt, H. R.; Schmidt, K.; Schweda, K.; Scurtu, A.; Seck, F.; Seddiki, S.; Selyuzhenkov, I.; Semennikov, A.; Senger, A.; Senger, P.; Shabunov, A.; Shao, Ming; Sharma, M. K.; Shumeiko, N.; Shumikhin, V.; Sikora, B.; Simakov, A.; Simon, C.; Simons, C.; Singaraju, R. N.; Singh, A. K.; Singh, B. K.; Singh, C. P.; Singhal, V.; Siwek-Wilczyńska, K.; Škoda, L.; Skwira-Chalot, I.; Som, I.; Song, Jihye; Sorokin, I.; Sosin, Z.; Soyk, D.; Staszel, P.; Stavinskiy, A.; Stephan, E.; Storozhyk, D.; Strikhanov, M.; Strohauer, S.; Stroth, J.; Sturm, C.; Sultanov, R.; Sun, Yongjie; Svoboda, O.; Szczygieł, R.; Talukdar, R.; Tang, Zebo; Tanha, M.; Tarasiuk, J.; Tarassenkova, O.; Târzilă, M.-G.; Tiflov, V.; Tischler, T.; Tlustý, P.; Toia, A.; Tolyhi, T.; Topil'skaya, N.; Trageser, C.; Trivedy, P.; Tsakov, I.; Tsyupa, Yu.; Turowiecki, A.; Uhlig, F.; Usenko, E.; Valin, I.; Vasiliev, T.; Vassiliev, I.; Verbitskaya, E.; Verhoeven, W.; Veshikov, A.; Visinka, R.; Viyogi, Y. P.; Volkov, S.; Volkov, Yu.; Vorobiev, A.; Voronin, A.; Vovchenko, V.; Vznuzdaev, E.; Vznuzdaev, M.; Wang, Dong; Wang, Yaping; Yi, Wang; Wendisch, C.; Wessels, J. P.; Wiebusch, M.; Wiechula, J.; Wiedemann, B.; Wielanek, D.; Wieloch, A.; Winckler, N.; Winter, M.; Wiśniewski, K.; Wohlfeld, D.; Wolf, Gy.; Sanguk, Won; Wüstenfeld, J.; Xiang, Changzhou; Nu, Xu; Yi, Jun-Gyu; Yin, Zhongbao; Yoo, In-Kwon; Yue, Qian; Yuldashev, B.; Yushmanov, I.; Zabołotny, W.; Zaitsev, Yu.; Zanevsky, Yu.; Zhalov, M.; Zhang, Ya Peng; Zhang, Yifei; Zhou, Daicui; Zhu, Xianglei; Zinchenko, A.; Zipper, W.; Żoładź, M.; Zrelov, P.; Zryuev, V.; Zumbruch, P.; Zyzak, M.

2014-11-01

We acknowledge support by the Seventh Framework Programme (FP7) of the European Commission through projects AIDA, CRISP and HadronPhysics3; the Bundesministerium für Bildung und Forschung, Germany, through the grants 05P09PXFC5, 05P12PXFCE, 05P12RFFC7, 05P12RFFCM, 05P12RFFCP, 05P12RGFCG,05P12RGGHM, 05P12VHFCE, 05P12VHFCF, 05PRVHFC7, and 06HD9123I; the Deutsche Forschungsgemeinschaft, Germany, grant GRK 1039; the Hessian Loewe Initiative through the Helmholtz International Center for FAIR (HIC4FAIR); the Helmholtz Graduate School HIRe; the Helmholtz Research School H-QM; the GSI Helmholzzentrum für Schwerionenforschung mbH, Germany, through F&E cooperations with Goethe-Universität Frankfurt, Justus-Liebig-Universität Gießen and Bergische Universität Wuppertal (WKAMPE1012); the Department of Science and Technology, Government of India; the Department of Atomic Energy, Government of India; the Council of Scientific and Industrial Research, Government of India; the University Grants Commission, Government of India; the Indo-FAIR Co-ordination Centre, Bose Institute, Kolkata, India; the Strategic Grants POSDRU/89/1.5/S/58852 and PN-II-ID-PCE-IDEI 34/05.10.2011, Romania; the NASR/CAPACITATI-Modul III, Romania, contract nr. 179EU; the NASR/NUCLEU Project PN09370103, Romania; the FAIR Russia Research Center (FRRC), Russia; and the Federal Agency for Atomic Research (Rosatom), Russia.

Validation of The Scenarios Designed For The Eu Registration of Pesticides

NASA Astrophysics Data System (ADS)

Piñeros Garcet, J. D.; de Nie, D.; Vanclooster, M.; Tiktak, A.; Klein, M.

As part of recent efforts to harmonise registration procedures for pesticides within the EU, a set of uniform principles were developed, setting out the detailed evaluation and decision making criteria for pesticide registration. The EU directive 91/414/EEC places great importance on the use of validated models to calculate Predicted Envi- ronmental Concentrations (PECs), as a basis for assessing the environmental risks and health effects. To be used in a harmonised registration process, the quality of PEC modelling needs to be assured. Quality assurance of mathematical modelling implies, amongst others, the validation of the environmental modelling scenarios. The FOrum for the CO-ordination of pesticide fate models and their USe (FOCUS), is the cur- rent platform where common modelling methodologies are designed and subjected for approval to the European authorities. In 2000, the FOCUS groundwater scenarios working group defined the procedures for realising tier 1 PEC groundwater calcula- tions for the active substances of plant protection products at the pan-european level. The procedures and guidelines were approved by the Standing Committee on Plant Health, and are now recommended for tier 1 PEC groundwater calculations in the reg-istration dossier. Yet, the working group also identified a range of uncertainties related to the validity of the present leaching scenarios. To mitigate some of these problems,the EU R&D project APECOP was designed and approved for support in the frame-work of the EU-FP5-Quality of Life Programme. One of the objectives of the project is to evaluate the appropriateness of the current Tier 1 groundwater scenarios. In this paper, we summarise the methodology and results of the scenarios validation.

Validation of The Scenarios Designed For The Eu Registration of Pesticides

NASA Astrophysics Data System (ADS)

Piñeros Garcet, J. D.; de Nie, D.; Vanclooster, M.; Tiktak, A.; Klein, M.; Jones, A.

As part of recent efforts to harmonise registration procedures for pesticides within the EU, a set of uniform principles were developed, setting out the detailed evaluation and decision making criteria for pesticide registration. The EU directive 91/414/EEC places great importance on the use of validated models to calculate Predicted Envi- ronmental Concentrations (PECs), as a basis for assessing the environmental risks and health effects. To be used in a harmonised registration process, the quality of PEC modelling needs to be assured. Quality assurance of mathematical modelling implies, amongst others, the validation of the environmental modelling scenarios. The FOrum for the CO-ordination of pesticide fate models and their USe (FOCUS), is the cur- rent platform where common modelling methodologies are designed and subjected for approval to the European authorities. In 2000, the FOCUS groundwater scenarios working group defined the procedures for realising tier 1 PEC groundwater calcula- tions for the active substances of plant protection products at the pan-european level. The procedures and guidelines were approved by the Standing Committee on Plant Health, and are now recommended for tier 1 PEC groundwater calculations in the reg- istration dossier. Yet, the working group also identified a range of uncertainties related to the validity of the present leaching scenarios. To mitigate some of these problems, the EU R&D project APECOP was designed and approved for support in the frame- work of the EU-FP5-Quality of Life Programme. One of the objectives of the project is to evaluate the appropriateness of the current Tier 1 groundwater scenarios. In this paper, we summarise the methodology and results of the scenarios validation.

PRoViScout: a planetary scouting rover demonstrator

NASA Astrophysics Data System (ADS)

Paar, Gerhard; Woods, Mark; Gimkiewicz, Christiane; Labrosse, Frédéric; Medina, Alberto; Tyler, Laurence; Barnes, David P.; Fritz, Gerald; Kapellos, Konstantinos

2012-01-01

Mobile systems exploring Planetary surfaces in future will require more autonomy than today. The EU FP7-SPACE Project ProViScout (2010-2012) establishes the building blocks of such autonomous exploration systems in terms of robotics vision by a decision-based combination of navigation and scientific target selection, and integrates them into a framework ready for and exposed to field demonstration. The PRoViScout on-board system consists of mission management components such as an Executive, a Mars Mission On-Board Planner and Scheduler, a Science Assessment Module, and Navigation & Vision Processing modules. The platform hardware consists of the rover with the sensors and pointing devices. We report on the major building blocks and their functions & interfaces, emphasizing on the computer vision parts such as image acquisition (using a novel zoomed 3D-Time-of-Flight & RGB camera), mapping from 3D-TOF data, panoramic image & stereo reconstruction, hazard and slope maps, visual odometry and the recognition of potential scientifically interesting targets.

Climate change impacts on hydropower in the Swiss and Italian Alps.

PubMed

Gaudard, Ludovic; Romerio, Franco; Dalla Valle, Francesco; Gorret, Roberta; Maran, Stefano; Ravazzani, Giovanni; Stoffel, Markus; Volonterio, Michela

2014-09-15

This paper provides a synthesis and comparison of methodologies and results obtained in several studies devoted to the impact of climate change on hydropower. By putting into perspective various case studies, we provide a broader context and improved understanding of climate changes on energy production. We also underline the strengths and weaknesses of the approaches used as far as technical, physical and economical aspects are concerned. Although the catchments under investigation are located close to each other in geographic terms (Swiss and Italian Alps), they represent a wide variety of situations which may be affected by differing evolutions for instance in terms of annual runoff. In this study, we also differentiate between run-of-river, storage and pumping-storage power plants. By integrating and comparing various analyses carried out in the framework of the EU-FP7 ACQWA project, this paper discusses the complexity as well as current and future issues of hydropower management in the entire Alpine region. © 2013 Elsevier B.V. All rights reserved.

The CLIMB Geoportal - A web-based dissemination and documentation platform for hydrological modelling data

NASA Astrophysics Data System (ADS)

Blaschek, Michael; Gerken, Daniel; Ludwig, Ralf; Duttmann, Rainer

2015-04-01

Geoportals are important elements of spatial data infrastructures (SDIs) that are strongly based on GIS-related web services. These services are basically meant for distributing, documenting and visualizing (spatial) data in a standardized manner; an important but challenging task especially in large scientific projects with a high number of data suppliers and producers from various countries. This presentation focuses on introducing the free and open-source based geoportal solution developed within the research project CLIMB (Climate Induced Changes on the Hydrology of Mediterranean Basins, www.climb-fp7.eu) that serves as the central platform for interchanging project-related spatial data and information. In this collaboration, financed by the EU-FP7-framework and coordinated at the LMU Munich, 21 partner institutions from nine European and non-European countries were involved. The CLIMB Geoportal (lgi-climbsrv.geographie.uni-kiel.de) stores and provides spatially distributed data about the current state and future changes of the hydrological conditions within the seven CLIMB test sites around the Mediterranean. Hydrological modelling outcome - validated by the CLIMB partners - is offered to the public in forms of Web Map Services (WMS), whereas downloading the underlying data itself through Web Coverage Services (WCS) is possible for registered users only. A selection of common indicators such as discharge, drought index as well as uncertainty measures including their changes over time were used in different spatial resolution. Besides map information, the portal enables the graphical display of time series of selected variables calculated by the individual models applied within the CLIMB-project. The implementation of the CLIMB Geoportal is finally based on version 2.0c5 of the open source geospatial content management system GeoNode. It includes a GeoServer instance for providing the OGC-compliant web services and comes with a metadata catalog (pycsw) as well as a built-in WebGIS-client based on GeoExt (GeoExplorer). PostgreSQL enhanced by PostGIS in versions 9.2.1/2.0.1 serves as database backend for all base data of the study sites and for the time series of relevant hydrological indicators. Spatial model results in raster-format are stored file-based as GeoTIFFs. Due to the high number of model outputs, the generation of metadata (xml) and graphical rendering instructions (sld) associated with each single layer of the WMS has been done automatically using the statistical software R. Additional applications that have been programmed during the project period include a Java-based interface for comfortable download of climate data that was initially needed as input data in hydrological modeling as well as a tool for displaying time series of selected risk indicators which is directly integrated into the portal structure implemented using Python (Django) and JavaScript. The presented CLIMB Geoportal shows that relevant results of even large international research projects involving many partners and varying national standards in data handling, can be effectively disseminated to stakeholders, policy makers and other interested parties. Thus, it is a successful example of using free and open-source software for providing long-term visibility and access to data produced within a particular (environmental) research project.

a New Initiative for Tiling, Stitching and Processing Geospatial Big Data in Distributed Computing Environments

NASA Astrophysics Data System (ADS)

Olasz, A.; Nguyen Thai, B.; Kristóf, D.

2016-06-01

Within recent years, several new approaches and solutions for Big Data processing have been developed. The Geospatial world is still facing the lack of well-established distributed processing solutions tailored to the amount and heterogeneity of geodata, especially when fast data processing is a must. The goal of such systems is to improve processing time by distributing data transparently across processing (and/or storage) nodes. These types of methodology are based on the concept of divide and conquer. Nevertheless, in the context of geospatial processing, most of the distributed computing frameworks have important limitations regarding both data distribution and data partitioning methods. Moreover, flexibility and expendability for handling various data types (often in binary formats) are also strongly required. This paper presents a concept for tiling, stitching and processing of big geospatial data. The system is based on the IQLib concept (https://github.com/posseidon/IQLib/) developed in the frame of the IQmulus EU FP7 research and development project (http://www.iqmulus.eu). The data distribution framework has no limitations on programming language environment and can execute scripts (and workflows) written in different development frameworks (e.g. Python, R or C#). It is capable of processing raster, vector and point cloud data. The above-mentioned prototype is presented through a case study dealing with country-wide processing of raster imagery. Further investigations on algorithmic and implementation details are in focus for the near future.

The FP7 ULTimateCO2 project: a study of the long term fate of CO2

NASA Astrophysics Data System (ADS)

Audigane, Pascal; Waldmann, Svenja; Pearce, Jonathan; Dimier, Alain; Le Gallo, Yann; Frykman, Peter; Maurand, Nicolas; Gherardi, Fabrizio; Yalamas, Thierry; Cremer, Holger; Spiers, Chris; Nussbaum, Christophe

2014-05-01

The objectives of the European FP7 ULTimateCO2 project are to study specific processes that could influence the long-term fate of geologically stored CO2, mainly: the trapping mechanisms occurring in the storage reservoir, the influence of fluid-rock interactions on mechanical integrity of caprock and well vicinity, and also the modifications induced at the regional scale (brine displacement, fault reactivation, hydrogeology changes...). A comprehensive approach combining laboratory experiments, numerical modeling and natural analogue studies is developed to assess all the processes mentioned above. A collection of data has been generated from natural and industrial (oil industry) analogues on the fluid flow and mechanical properties, structure, and mineralogy of faults and fractures that could affect the long-term storage capacity of underground CO2 storage sites. To address geochemical trapping at reservoir scale, an experimental approach is developed using sandstone core materials in batch reactive mode with CO2 and impurities at reservoir pressure and temperature conditions. Three inter-related lines of laboratory experiments investigate the long-term evolution of the mechanical properties and sealing integrity of fractured and faulted caprocks using Opalinus clay of Mont Terri Gallery (Switzerland), an analogue for caprock well investigated in the past for nuclear waste disposal purpose. To evaluate the interactions between CO2 (and formation fluid) and the well environment (formation, cement, casing) and to assess the consequences of these interactions on the transport properties of well materials, a 1 to 1 scale experiment has been set in the Mont Terri Gallery Opalinus clay to reproduce classical well objects (cemented annulus, casing and cement plug) perforating caprock formations. An extensive program of numerical modeling is also developed to calibrate, to reproduce and to extrapolate the experimental results at longer time scales including uncertainty assessment methods. www.ultimateco2.eu

The Data Rescue @ Home Project

NASA Astrophysics Data System (ADS)

Stickler, A.; Allan, R.; Valente, M. A.; Tinz, B.; Brönnimann, S.

2012-04-01

Climate science as a whole as well as reanalyses as a special case can significantly profit from the recovery, imaging and digitisation of historical observations. The importance of this fact is reflected in large, global data rescue projects and initiatives such as the Atmospheric Circulation Reconstructions over the Earth (ACRE, www.met-acre.org) or the EU FP7 ERA-CLIM project (www.era-clim.eu). From the time before 1957, there are still large amounts of surface data e.g. from former colonies and from overseas territories of European countries )e.g. Portugal, France and Germany) that need to be rescued. Also in case of the very early upper-air observations before the 1930s, even Europe and North America still hold an important quantity of data to be recovered in digital form. Here, we present the web platform "Data Rescue @ Home" (www.data-rescue-at-home.org), which has been developed at ETH Zurich and Oeschger Centre for Climate Change Research, and which has been designed to take advantage of the voluntary assistance of the thousands of people on the web who are interested in climate or old weather data. On the website, these volunteers can enter meteorological data shown on digital images into entry masks that resemble the original. By registering, the users get access to their personal digitisation statistics and help optimising the project. At the moment, 4 digitisation projects are online: One project is dealing with German upper-air data from the Second World War period. In a second project, station data from Tulagi (Solomon Islands) is being digitised. Finally, two collaborative projects have been included: One in cooperation with the Instituto Dom Luiz (Univ. Lisbon, Portugal), where Portuguese station data from Angra (Azores) is digitised, and a further one in cooperation with the German Meteorological Service (DWD), in which precipitation data from former German colonies is being digitised. On our poster, we will report on the status of the projects, technical details of the data preparation, and give examples of how the platform can be used by external partners to digitise large amounts of data at relatively low cost.

Environmental change and water-related, vector borne diseases in eastern Africa: the HEALTHY FUTURES project

NASA Astrophysics Data System (ADS)

Taylor, David; Kienberger, Stefan; Tompkins, Adrian

2015-04-01

Pathogens that spend time outside the human body, and any organisms involved in their transmission, have particular ecological requirements; as environment, including climate, conditions change, then the transmission characteristics of associated pathogens - and the diseases caused - are also likely to vary. Relationships between environment and health in many parts of the world remain poorly studied and are often overlooked, however. This is particularly the case in developing countries, because of budgetary and available expertise constraints. Moreover the relationship is often confounded by other factors. These other factors contribute to human vulnerability, and thus to the overall disease risk due to environmental change. This presentation will highlight the importance of environmental, including climate, change information to a better understanding of the risks to health of projected future environmental changes, and to the more efficient and effective use of scarce health resources in the developing world. The paper will focus on eastern Africa, and in particular the health effects of future projected environmental change impacts on water-related, vector borne diseases in the East African Community region. Moreover the paper will highlight how the EU FP7-funded project HEALTHY FUTURES is, through a broadly-based, integrative approach that distinguishes environmental change-induced health hazard from health risk aims to support the health decisions making process, thereby attempting to help mitigate negative health impacts.

Soil wetting patterns of vegetation and inter-patches following single and repeated wildfires

NASA Astrophysics Data System (ADS)

González, Óscar; Malvar, Maruxa; van den Elsen, Erik; Hosseini, mohammadreza; Coelho, Celeste; Ritsema, Coen; Bautista, Susana; Keizer, Jan Jacob; Cerdà, Artemi

2015-04-01

Although wildfires spread in Mediterranean areas are considered a natural processes, the expected increase in fire frequency has raised concerns about the systems' future resilience (Pausas, 2004). Besides more frequent, future wildfires can become more severe and produce more pronounced changes in topsoil properties, vegetation and litter (Cerdá and Mataix-Solera, 2009). To deal with challenges, the EU funded CASCADE and RECARE projects, which are currently assessing soil threats and tipping-points for land degradation in a climatic gradient across Europe. The present research was developed in Portugal and aims to find relationships between fire frequency and soil wetting patterns following single versus repeated wildfires. In September 2012, a wildfire burnt 3000 ha. of Pine stands and shrub vegetation in the vicinity of Viseu district, North-Central Portugal. Analyses according to the available burnt-area maps (1975-2012), discriminated areas that has been burned 1x (called SD) and 4x (called D) times. In order to evaluate the post-fire soil surface moisture patterns, 6 slopes (3 in SD and 3 in D) were selected and a balanced experimental design with 72 soil moisture sensors (EC5 and GS3, from Decagon devices) was implemented under shrubs (n=18) and on bare (n=18) soil environments, at 2.5 cm and 7.5 cm soil depth each. The spatio-temporal occurrence of soil water repellence (SWR) (Keizer et al., 2008; Prats et al., 2013; Santos et al., 2014) was monthly assessed through the MED test at 2.5 cm and 7.5 cm soil depth into 5 sampling points located at regular distances along a transect running from the top to bottom of a selected slope in SD and D. Automatic and totalize rainfall gauges were also installed across the study area. Preliminary results showed that soil wetting patterns and SWR occurrence differs between SD, D sites and, between soil environment (under shrubs and on bare soil areas). SWR were more pronounced on the SD than in D, affecting soil wetting cycles. Soil moisture content and antecedent rainfall were both correlated with SWR, although insufficient to predict the temporal variations. Antecedent and maximum soil moisture were close related with the SWR status and data analyses showed a top-down breaking mechanism on the SWR Acknowledgements. The research projects CASCADE FP7 (ENV.2011.2.1.4, www.cascade-project.eu) AND RECARE FP7 (n° 603498, http://recare-project.eu/) supported this research. References. Cerdá, A., Mataix-Solera, J., 2009. Incendios forestales en España. Ecosistemas terrestres y suelos. En: Efectos de los incendios forestales sobre los suelos en España. Cerda and Mataix-Solera (eds). Universidad de Valencia, Valencia (España). 529 pp. Keizer, J.J., Doerr, S.H., Malvar, M.C., Prats, S.A., Ferreira, R.S.V., Oñate, M.G., Coelho, C.O.A., Ferreira, A.J.D., 2008. Temporal variation in topsoil water repellency in two recently burnt eucalypt stands in north-central Portugal. Catena 74 (3), 192-204. Pausas, J., 2004. Changes in fire and climate in the eastern Iberian Peninsula (Mediterranean basin). Climatic Change, 63: 330-340. Prats, S.A., Malvar, M., Vieira, D.C.S., McDonald, L., Keizer, J.J. 2013. Effectiveness of hydromulching to reduce runoff and erosion in a recently burnt pine plantation in central Portugal. Land Degradation and Development. DOI: 10.1002/ldr.2236. Santos J.M., Verheijen F.G.A., Wahren F.T., Wahren A., Feger K.H., Bernard-Jannin L., Rial Rivas M.E., Keizer J.J., Nunes J.P. 2014. Soil Water Repellency dynamics in Pine and Eucalypt plantations in Portugal - A high resolution time series. Land Degradation & Development. DOI: 10.1002/ldr.2251.

BREAD: a European coordination action for broadband for all

NASA Astrophysics Data System (ADS)

Van Daele, P.

2006-10-01

The BREAD - co-ordination action, funded by the European Commission through the Framework 6 Programme (FP6) aims at developing a multi-disciplinary approach for the realization of the 'Broadband for All' concept within Europe, bringing together societal, economic, regulatory and technological disciplines and presenting information from regional "success stories" of actual deployment. The EU objective of achieving "Broadband for All" will not be reached by solely a 'technology push' strategy but will need this multi-disciplinary approach and sharing of views and knowledge to develop new strategies and good practice recommendations in the area of 'Broadband for All'. As a co-ordination action the project wants to unite all players active in the field of the end-to-end broadband provisioning for all. It performs a multi-technological analysis of the current and evolving situation, starting from the roadmap information generated by different projects and IST instruments which focus on specific technological domains. The BREAD consortium simultaneously studies the techno-economic, societal and regulatory aspects of this "Broadband for All" concept. It tries to identify the impact of the EU regulatory framework on the successful implementation of new broadband communication services.

DFT investigation on electronic, magnetic, mechanical and thermodynamic properties under pressure of some EuMO3 (M  =  Ga, In) perovskites

NASA Astrophysics Data System (ADS)

Dar, Sajad Ahmad; Srivastava, Vipul; Sakalle, Umesh Kumar; Parey, Vanshree; Pagare, Gitanjali

2017-10-01

The structural, electronic, magnetic and elastic properties of cubic EuMO3 (M  =  Ga, In) perovskites has been successfully predicted within well accepted density functional theory using full potential linearized augmented plane wave (FP-LAPW). The structural study reveals ferromagnetic stability for both the compounds. The Hubbard correlation (GGA+U) calculated spin polarized electronic band and density of states presents half-metallic nature for both the compounds. The magnetic moments calculated with different approximations were found to be approximately 6 µ B for EuGaO3 and approximately 7 µ B for EuInO3. The three independent elastic constants (C 11, C 12, C 44) have been used for the prediction of mechanical properties like Young modulus (Y), Shear modulus (G), Poisson ratio (ν), Anisotropic factor (A) under pressure. The B/G ratio presents the ductile nature for both compounds. The thermodynamic parameters like specific heat capacity, thermal expansion, Grüneisen parameter and Debye temperature etc have also been analyzed in the temperature range 0-900 K and pressure range from 0 to 30 GPa.

The ASTARTE Paleotsunami and Mass Transport Deposits data bases - web-based references for tsunami and submarine landslide research around Europe

NASA Astrophysics Data System (ADS)

De Martini, Paolo Marco; Patera, Antonio; Orefice, Simone; Paris, Raphael; Völker, David; Lastras, Galderic; Terrinha, Pedro; Noiva, João; Smedile, Alessandra; Pantosti, Daniela; Hunt, James; Gutscher, Marc-Andre; Migeon, Sébastien; Papadopoulos, Gerassimos; Triantafyllou, Ioanna; Yalciner, Ahmet C.

2017-04-01

EU project ASTARTE aims at developing a higher level of tsunami hazard assessment in the North East Atlantic, Mediterranean and Connected seas (NEAM) region by a combination of field work, experimental work, numerical modeling and technical development. The project is a cooperative work of 26 institutes from 16 countries and links together the description of past tsunamigenic events, the identification and characterization of tsunami sources, the calculation of the impact of such events, and the development of adequate resilience and risks mitigation strategies (www.astarte.eu). Within ASTARTE two web-based data bases on Paleotsunami and Mass Transport Deposits in the NEAM areas were created with the purpose to be the future information repositories for tsunami research in Europe.The aim is to integrate every existing official scientific reports and peer reviewed papers on these topics and update on new entries every 6-12 months, hosting information and detailed data, that are crucial e.g for tsunami modeling. A relational database managed by ArcGIS for Desktop 10.x software has been implemented. One of the final goals of the project is the public sharing of the archived datasets through a web-based map service that will allow visualizing, querying, analyzing, and interpreting all datasets. The interactive map service will be hosted by ArcGIS Online and will deploy the cloud capabilities of the portal. Any interested users will be able to access the online GIS resources through any Internet browser or specific apps that run on desktop machines, smartphones, or tablets and will be able to use the analytical tools, key tasks, and workflows of the service.We will present the data bases structure and topics as well as their ArcGIS Online version. The research leading to these results has received funding from the European Union's Seventh Framework Programme (FP7/2007-2013) under grant agreement n° 603839 (Project ASTARTE - Assessment, Strategy and Risk Reduction for Tsunamis in Europe).

The SOLUTIONS project: challenges and responses for present and future emerging pollutants in land and water resources management.

PubMed

Brack, Werner; Altenburger, Rolf; Schüürmann, Gerrit; Krauss, Martin; López Herráez, David; van Gils, Jos; Slobodnik, Jaroslav; Munthe, John; Gawlik, Bernd Manfred; van Wezel, Annemarie; Schriks, Merijn; Hollender, Juliane; Tollefsen, Knut Erik; Mekenyan, Ovanes; Dimitrov, Saby; Bunke, Dirk; Cousins, Ian; Posthuma, Leo; van den Brink, Paul J; López de Alda, Miren; Barceló, Damià; Faust, Michael; Kortenkamp, Andreas; Scrimshaw, Mark; Ignatova, Svetlana; Engelen, Guy; Massmann, Gudrun; Lemkine, Gregory; Teodorovic, Ivana; Walz, Karl-Heinz; Dulio, Valeria; Jonker, Michiel T O; Jäger, Felix; Chipman, Kevin; Falciani, Francesco; Liska, Igor; Rooke, David; Zhang, Xiaowei; Hollert, Henner; Vrana, Branislav; Hilscherova, Klara; Kramer, Kees; Neumann, Steffen; Hammerbacher, Ruth; Backhaus, Thomas; Mack, Juliane; Segner, Helmut; Escher, Beate; de Aragão Umbuzeiro, Gisela

2015-01-15

SOLUTIONS (2013 to 2018) is a European Union Seventh Framework Programme Project (EU-FP7). The project aims to deliver a conceptual framework to support the evidence-based development of environmental policies with regard to water quality. SOLUTIONS will develop the tools for the identification, prioritisation and assessment of those water contaminants that may pose a risk to ecosystems and human health. To this end, a new generation of chemical and effect-based monitoring tools is developed and integrated with a full set of exposure, effect and risk assessment models. SOLUTIONS attempts to address legacy, present and future contamination by integrating monitoring and modelling based approaches with scenarios on future developments in society, economy and technology and thus in contamination. The project follows a solutions-oriented approach by addressing major problems of water and chemicals management and by assessing abatement options. SOLUTIONS takes advantage of the access to the infrastructure necessary to investigate the large basins of the Danube and Rhine as well as relevant Mediterranean basins as case studies, and puts major efforts on stakeholder dialogue and support. Particularly, the EU Water Framework Directive (WFD) Common Implementation Strategy (CIS) working groups, International River Commissions, and water works associations are directly supported with consistent guidance for the early detection, identification, prioritisation, and abatement of chemicals in the water cycle. SOLUTIONS will give a specific emphasis on concepts and tools for the impact and risk assessment of complex mixtures of emerging pollutants, their metabolites and transformation products. Analytical and effect-based screening tools will be applied together with ecological assessment tools for the identification of toxicants and their impacts. The SOLUTIONS approach is expected to provide transparent and evidence-based candidates or River Basin Specific Pollutants in the case study basins and to assist future review of priority pollutants under the WFD as well as potential abatement options. Copyright © 2014 Elsevier B.V. All rights reserved.

Use of finger-prick dried blood spots (fpDBS) and capillary electrophoresis for carbohydrate deficient transferrin (CDT) screening in forensic toxicology.

PubMed

Bertaso, Anna; Sorio, Daniela; Vandoros, Anthula; De Palo, Elio F; Bortolotti, Federica; Tagliaro, Franco

2016-10-01

Continued progress in chronic alcohol abuse investigation requires the development of less invasive procedures for screening purposes. The application of finger-prick and related dried blood spots (fpDBS) for carbohydrate deficient transferrin (CDT) detection appears suitable for this aim. Therefore, the goal of this project was to develop a screening method for CDT using fpDBS with CZE analysis. Blood samples prepared by finger-prick were placed on DBS cards and left to air dry; each dried fpDBS disc was shredded into small pieces and suspended in acid solution (60 μL of HCl 120 mmol/L). After centrifugation (10 min at 1500 × g), the collected sample was adjusted to pH 3.5. After an overnight incubation, the pH was neutralised and an iron rich solution was added. After 1 h, CZE analysis was carried out. A group of 47 individuals was studied. Parallel serum samples were collected from each investigated subject and the %CDT for each sample was measured using HPLC and CZE techniques. The fpDBS transferrin sialo isoform electropherograms were similar to those obtained with serum. Moreover, fpDBS CZE CDT percentage levels demonstrated significant statistical correlation with those obtained from serum for both HPLC and CZE %CDT (p < 0.01; r 2 = 0.8913 and 0.8976, respectively), with %CDT from 0.8 to 13.7% for fpDBS and from 0.7 to 12.7% for serum. The newly developed fpDBS procedure for CDT analysis provides a simple and inexpensive tool for use in population screening. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

A vision and strategy for the virtual physiological human: 2012 update

PubMed Central

Hunter, Peter; Chapman, Tara; Coveney, Peter V.; de Bono, Bernard; Diaz, Vanessa; Fenner, John; Frangi, Alejandro F.; Harris, Peter; Hose, Rod; Kohl, Peter; Lawford, Pat; McCormack, Keith; Mendes, Miriam; Omholt, Stig; Quarteroni, Alfio; Shublaq, Nour; Skår, John; Stroetmann, Karl; Tegner, Jesper; Thomas, S. Randall; Tollis, Ioannis; Tsamardinos, Ioannis; van Beek, Johannes H. G. M.; Viceconti, Marco

2013-01-01

European funding under Framework 7 (FP7) for the virtual physiological human (VPH) project has been in place now for 5 years. The VPH Network of Excellence (NoE) has been set up to help develop common standards, open source software, freely accessible data and model repositories, and various training and dissemination activities for the project. It is also working to coordinate the many clinically targeted projects that have been funded under the FP7 calls. An initial vision for the VPH was defined by the FP6 STEP project in 2006. In 2010, we wrote an assessment of the accomplishments of the first two years of the VPH in which we considered the biomedical science, healthcare and information and communications technology challenges facing the project (Hunter et al. 2010 Phil. Trans. R. Soc. A 368, 2595–2614 (doi:10.1098/rsta.2010.0048)). We proposed that a not-for-profit professional umbrella organization, the VPH Institute, should be established as a means of sustaining the VPH vision beyond the time-frame of the NoE. Here, we update and extend this assessment and in particular address the following issues raised in response to Hunter et al.: (i) a vision for the VPH updated in the light of progress made so far, (ii) biomedical science and healthcare challenges that the VPH initiative can address while also providing innovation opportunities for the European industry, and (iii) external changes needed in regulatory policy and business models to realize the full potential that the VPH has to offer to industry, clinics and society generally. PMID:24427536

A vision and strategy for the virtual physiological human: 2012 update.

PubMed

Hunter, Peter; Chapman, Tara; Coveney, Peter V; de Bono, Bernard; Diaz, Vanessa; Fenner, John; Frangi, Alejandro F; Harris, Peter; Hose, Rod; Kohl, Peter; Lawford, Pat; McCormack, Keith; Mendes, Miriam; Omholt, Stig; Quarteroni, Alfio; Shublaq, Nour; Skår, John; Stroetmann, Karl; Tegner, Jesper; Thomas, S Randall; Tollis, Ioannis; Tsamardinos, Ioannis; van Beek, Johannes H G M; Viceconti, Marco

2013-04-06

European funding under Framework 7 (FP7) for the virtual physiological human (VPH) project has been in place now for 5 years. The VPH Network of Excellence (NoE) has been set up to help develop common standards, open source software, freely accessible data and model repositories, and various training and dissemination activities for the project. It is also working to coordinate the many clinically targeted projects that have been funded under the FP7 calls. An initial vision for the VPH was defined by the FP6 STEP project in 2006. In 2010, we wrote an assessment of the accomplishments of the first two years of the VPH in which we considered the biomedical science, healthcare and information and communications technology challenges facing the project (Hunter et al. 2010 Phil. Trans. R. Soc. A 368, 2595-2614 (doi:10.1098/rsta.2010.0048)). We proposed that a not-for-profit professional umbrella organization, the VPH Institute, should be established as a means of sustaining the VPH vision beyond the time-frame of the NoE. Here, we update and extend this assessment and in particular address the following issues raised in response to Hunter et al.: (i) a vision for the VPH updated in the light of progress made so far, (ii) biomedical science and healthcare challenges that the VPH initiative can address while also providing innovation opportunities for the European industry, and (iii) external changes needed in regulatory policy and business models to realize the full potential that the VPH has to offer to industry, clinics and society generally.

TBVAC2020: Advancing Tuberculosis Vaccines from Discovery to Clinical Development.

PubMed

Kaufmann, Stefan H E; Dockrell, Hazel M; Drager, Nick; Ho, Mei Mei; McShane, Helen; Neyrolles, Olivier; Ottenhoff, Tom H M; Patel, Brij; Roordink, Danielle; Spertini, François; Stenger, Steffen; Thole, Jelle; Verreck, Frank A W; Williams, Ann

2017-01-01

TBVAC2020 is a research project supported by the Horizon 2020 program of the European Commission (EC). It aims at the discovery and development of novel tuberculosis (TB) vaccines from preclinical research projects to early clinical assessment. The project builds on previous collaborations from 1998 onwards funded through the EC framework programs FP5, FP6, and FP7. It has succeeded in attracting new partners from outstanding laboratories from all over the world, now totaling 40 institutions. Next to the development of novel vaccines, TB biomarker development is also considered an important asset to facilitate rational vaccine selection and development. In addition, TBVAC2020 offers portfolio management that provides selection criteria for entry, gating, and priority settings of novel vaccines at an early developmental stage. The TBVAC2020 consortium coordinated by TBVI facilitates collaboration and early data sharing between partners with the common aim of working toward the development of an effective TB vaccine. Close links with funders and other consortia with shared interests further contribute to this goal.

TBVAC2020: Advancing Tuberculosis Vaccines from Discovery to Clinical Development

PubMed Central

Kaufmann, Stefan H. E.; Dockrell, Hazel M.; Drager, Nick; Ho, Mei Mei; McShane, Helen; Neyrolles, Olivier; Ottenhoff, Tom H. M.; Patel, Brij; Roordink, Danielle; Spertini, François; Stenger, Steffen; Thole, Jelle; Verreck, Frank A. W.; Williams, Ann; Britton, Warwick

2017-01-01

TBVAC2020 is a research project supported by the Horizon 2020 program of the European Commission (EC). It aims at the discovery and development of novel tuberculosis (TB) vaccines from preclinical research projects to early clinical assessment. The project builds on previous collaborations from 1998 onwards funded through the EC framework programs FP5, FP6, and FP7. It has succeeded in attracting new partners from outstanding laboratories from all over the world, now totaling 40 institutions. Next to the development of novel vaccines, TB biomarker development is also considered an important asset to facilitate rational vaccine selection and development. In addition, TBVAC2020 offers portfolio management that provides selection criteria for entry, gating, and priority settings of novel vaccines at an early developmental stage. The TBVAC2020 consortium coordinated by TBVI facilitates collaboration and early data sharing between partners with the common aim of working toward the development of an effective TB vaccine. Close links with funders and other consortia with shared interests further contribute to this goal. PMID:29046674

The Philosophy and Approach on Which the PROFILES Project Is Based

ERIC Educational Resources Information Center

Holbrook, Jack; Rannikmäe, Miia

2014-01-01

This article sets out to describe the PROFILES project, a European Commission FP7 science and society project, addresses problems and issues in science education by guiding teachers to embrace a range of teaching factors, such as a context-based approach, motivational constructivist learning; student centred inquiry teaching; enhancing cognitive…

Modelling tools for managing Induced RiverBank Filtration MAR schemes

NASA Astrophysics Data System (ADS)

De Filippis, Giovanna; Barbagli, Alessio; Marchina, Chiara; Borsi, Iacopo; Mazzanti, Giorgio; Nardi, Marco; Vienken, Thomas; Bonari, Enrico; Rossetto, Rudy

2017-04-01

Induced RiverBank Filtration (IRBF) is a widely used technique in Managed Aquifer Recharge (MAR) schemes, when aquifers are hydraulically connected with surface water bodies, with proven positive effects on quality and quantity of groundwater. IRBF allows abstraction of a large volume of water, avoiding large decrease in groundwater heads. Moreover, thanks to the filtration process through the soil, the concentration of chemical species in surface water can be reduced, thus becoming an excellent resource for the production of drinking water. Within the FP7 MARSOL project (demonstrating Managed Aquifer Recharge as a SOLution to water scarcity and drought; http://www.marsol.eu/), the Sant'Alessio IRBF (Lucca, Italy) was used to demonstrate the feasibility and technical and economic benefits of managing IRBF schemes (Rossetto et al., 2015a). The Sant'Alessio IRBF along the Serchio river allows to abstract an overall amount of about 0.5 m3/s providing drinking water for 300000 people of the coastal Tuscany (mainly to the town of Lucca, Pisa and Livorno). The supplied water is made available by enhancing river bank infiltration into a high yield (10-2 m2/s transmissivity) sandy-gravelly aquifer by rising the river head and using ten vertical wells along the river embankment. A Decision Support System, consisting in connected measurements from an advanced monitoring network and modelling tools was set up to manage the IRBF. The modelling system is based on spatially distributed and physically based coupled ground-/surface-water flow and solute transport models integrated in the FREEWAT platform (developed within the H2020 FREEWAT project - FREE and Open Source Software Tools for WATer Resource Management; Rossetto et al., 2015b), an open source and public domain GIS-integrated modelling environment for the simulation of the hydrological cycle. The platform aims at improving water resource management by simplifying the application of EU water-related Directives and at facilitating the use of modeling environments and GIS tools for storage, management and visualization of large spatial datasets. The groundwater flow and solute transport model was built using FREEWAT, where MODFLOW-2005 and MT3DMS are integrated. The aquifer of the Sant'Alessio plain was discretized using square cells 100 m2 wide and two model layers, a silty-sandy superficial cover and the sandy-gravelly aquifer. Hydraulic connection with the Serchio river and exploitation of the aquifer through the Sant'Alessio well field were simulated. The aquifer model layer was further refined to simulate advection, dispersion, sorption and degradation of contaminants within the river. The objectives are: (i) estimating induced infiltration rates and travel times, (ii) optimizing groundwater exploitation in complex well field schemes, (iii) preventing pollution events, (iv) estimating time for remedial actions. Acknowledgements This paper is presented within the framework of the projects FP7 MARSOL and H2020 FREEWAT. The MARSOL project has received funding from the European Union's Seventh Framework Programme for Research, Technological Development and Demonstration under grant agreement no 619120. The FREEWAT project has received funding from the European Union's HORIZON 2020

Glycemic Control Indices and Their Aggregation in the Prediction of Nocturnal Hypoglycemia From Intermittent Blood Glucose Measurements.

PubMed

Sampath, Sivananthan; Tkachenko, Pavlo; Renard, Eric; Pereverzev, Sergei V

2016-11-01

Despite the risk associated with nocturnal hypoglycemia (NH) there are only a few methods aiming at the prediction of such events based on intermittent blood glucose monitoring data. One of the first methods that potentially can be used for NH prediction is based on the low blood glucose index (LBGI) and suggested, for example, in Accu-Chek® Connect as a hypoglycemia risk indicator. On the other hand, nowadays there are other glucose control indices (GCI), which could be used for NH prediction in the same spirit as LBGI. In the present study we propose a general approach of combining NH predictors constructed from different GCI. The approach is based on a recently developed strategy for aggregating ranking algorithms in machine learning. NH predictors have been calibrated and tested on data extracted from clinical trials, performed in EU FP7-funded project DIAdvisor. Then, to show a portability of the method we have tested it on another dataset that was received from EU Horizon 2020-funded project AMMODIT. We exemplify the proposed approach by aggregating NH predictors that have been constructed based on 4 GCI associated with hypoglycemia. Even though these predictors have been preliminary optimized to exhibit better performance on the considered dataset, our aggregation approach allows a further performance improvement. On the dataset, where a portability of the proposed approach has been demonstrated, the aggregating predictor has exhibited the following performance: sensitivity 77%, specificity 83.4%, positive predictive value 80.2%, negative predictive value 80.6%, which is higher than conventionally considered as acceptable. The proposed approach shows potential to be used in telemedicine systems for NH prediction. © 2016 Diabetes Technology Society.

Understanding and predicting the impact of extreme storms events on European coastlines: the MICORE approach

NASA Astrophysics Data System (ADS)

Ciavola, P.

2009-04-01

Both the EU and The United Nations are now taking seriously the predicted climate change scenarios of the IPCC. Of particular relevance to Integrated Coastal Zone Management is the predicted increase in the intensity and frequency of powerful storm events characterised by larger peak wind speeds and consequently larger waves. Engineering has usually been favoured in the past as the best option for disaster mitigation at the coast. However, most engineering works are constrained by economics, and a compromise is sought between the potential threat to lives and property and the resources available for design and construction. Furthermore, the design of structures is based on predicted extreme events which themselves are subject to uncertainty, especially in a rapidly changing global climate. The huge damage to the city of New Orleans by Hurricane Katrina illustrates clearly what can go wrong when the engineering design is subjected to forcing beyond its design limits and when civil evacuation and management plans fail. The proposed paper will address the issue of encouraging and facilitating exchange of information on storm impacts produced by nationally funded projects in Member States; establishing robust data management and data quality control and engaging with stakeholders and end users to optimise dissemination strategies. It will heavily rely on the information produced by the MICORE Project (FP7 contract 202798), using and enlarging the database collated by the project regarding the characteristics of extreme storm events occurred in the last 50 years. The MICORE project (www.micore.eu) will provide the knowledge necessary to assess the present day risks and to study the economic and social impact of future severe storm events. Together, these elements will have an important strategic impact on the safety of the people living in coastal areas and upon decision processes aimed at minimising the economic consequences of extreme events. The project will also investigate with stakeholders and end-users the possibilities of producing EU-wide guidelines for a viable and reliable risk mitigation strategy. One of the initial main objectives of MICORE is to produce an up-to-date data base for each partner country that includes: an historical review of storms; an inventory of data related to the forcing signals; quantification of the morphological response of coastal systems to storms and to sequences of storms; an assessment of socio-economic impact; a description of existing civil protection schemes and interventions. The MICORE project will identify indices for coastal vulnerability to erosion with an integrated EU perspective using the standardised data bases assembled for all member states. It will also recommend future data collection requirements that best serve the needs of coastal managers. Here an area of innovation in the project is the standardization in the production of vulnerability matrices for evaluation of society impact from storms.

On safe ground? Analysis of European urban geohazards using satellite radar interferometry

NASA Astrophysics Data System (ADS)

Capes, Renalt; Teeuw, Richard

2017-06-01

Urban geological hazards involving ground instability can be costly, dangerous, and affect many people, yet there is little information about the extent or distribution of geohazards within Europe's urban areas. A reason for this is the impracticality of measuring ground instability associated with the many geohazard processes that are often hidden beneath buildings and are imperceptible to conventional geological survey detection techniques. Satellite radar interferometry, or InSAR, offers a remote sensing technique to map mm-scale ground deformation over wide areas given an archive of suitable multi-temporal data. The EC FP7 Space project named PanGeo (2011-2014), used InSAR to map areas of unstable ground in 52 of Europe's cities, representing ∼15% of the EU population. In partnership with Europe's national geological surveys, the PanGeo project developed a standardised geohazard-mapping methodology and recorded 1286 instances of 19 types of geohazard covering 18,000 km2. Presented here is an analysis of the results of the PanGeo-project output data, which provides insights into the distribution of European urban geohazards, their frequency and probability of occurrence. Merging PanGeo data with Eurostat's GeoStat data provides a systematic estimate of population exposures. Satellite radar interferometry is shown to be as a valuable tool for the systematic detection and mapping of urban geohazard phenomena.

7 CFR 654.1 - Purpose and scope.

Code of Federal Regulations, 2014 CFR

2014-01-01

...) Federal financially-assisted projects. (i) Watershed Protection and Flood Prevention (WP&FP). See part 622...) Emergency Watershed Protection (EWP). See part 624 of this title. (4) Great Plains Conservation Program (GP...

7 CFR 654.1 - Purpose and scope.

Code of Federal Regulations, 2010 CFR

2010-01-01

...) Federal financially-assisted projects. (i) Watershed Protection and Flood Prevention (WP&FP). See part 622...) Emergency Watershed Protection (EWP). See part 624 of this title. (4) Great Plains Conservation Program (GP...

7 CFR 654.1 - Purpose and scope.

Code of Federal Regulations, 2012 CFR

2012-01-01

...) Federal financially-assisted projects. (i) Watershed Protection and Flood Prevention (WP&FP). See part 622...) Emergency Watershed Protection (EWP). See part 624 of this title. (4) Great Plains Conservation Program (GP...

7 CFR 654.1 - Purpose and scope.

Code of Federal Regulations, 2013 CFR

2013-01-01

...) Federal financially-assisted projects. (i) Watershed Protection and Flood Prevention (WP&FP). See part 622...) Emergency Watershed Protection (EWP). See part 624 of this title. (4) Great Plains Conservation Program (GP...

7 CFR 654.1 - Purpose and scope.

Code of Federal Regulations, 2011 CFR

2011-01-01

...) Federal financially-assisted projects. (i) Watershed Protection and Flood Prevention (WP&FP). See part 622...) Emergency Watershed Protection (EWP). See part 624 of this title. (4) Great Plains Conservation Program (GP...

AMISS - Active and passive MIcrowaves for Security and Subsurface imaging

NASA Astrophysics Data System (ADS)

Soldovieri, Francesco; Slob, Evert; Turk, Ahmet Serdar; Crocco, Lorenzo; Catapano, Ilaria; Di Matteo, Francesca

2013-04-01

The FP7-IRSES project AMISS - Active and passive MIcrowaves for Security and Subsurface imaging is based on a well-combined network among research institutions of EU, Associate and Third Countries (National Research Council of Italy - Italy, Technische Universiteit Delft - The Netherlands, Yildiz Technical University - Turkey, Bauman Moscow State Technical University - Russia, Usikov Institute for Radio-physics and Electronics and State Research Centre of Superconductive Radioelectronics "Iceberg" - Ukraine and University of Sao Paulo - Brazil) with the aims of achieving scientific advances in the framework of microwave and millimeter imaging systems and techniques for security and safety social issues. In particular, the involved partners are leaders in the scientific areas of passive and active imaging and are sharing their complementary knowledge to address two main research lines. The first one regards the design, characterization and performance evaluation of new passive and active microwave devices, sensors and measurement set-ups able to mitigate clutter and increase information content. The second line faces the requirements to make State-of-the-Art processing tools compliant with the instrumentations developed in the first line, suitable to work in electromagnetically complex scenarios and able to exploit the unexplored possibilities offered by new instrumentations. The main goals of the project are: 1) Development/improvement and characterization of new sensors and systems for active and passive microwave imaging; 2) Set up, analysis and validation of state of art/novel data processing approach for GPR in critical infrastructure and subsurface imaging; 3) Integration of state of art and novel imaging hardware and characterization approaches to tackle realistic situations in security, safety and subsurface prospecting applications; 4) Development and feasibility study of bio-radar technology (system and data processing) for vital signs detection and detection/characterization of human beings in complex scenarios. These goals are planned to be reached following a plan of research activities and researchers secondments which cover a period of three years. ACKNOWLEDGMENTS This research has been performed in the framework of the "Active and Passive Microwaves for Security and Subsurface imaging (AMISS)" EU 7th Framework Marie Curie Actions IRSES project (PIRSES-GA-2010-269157).

Empowering citizens in international governance of nanotechnologies.

PubMed

Malsch, Ineke; Subramanian, Vrishali; Semenzin, Elena; Hristozov, Danail; Marcomini, Antonio; Mullins, Martin; Hester, Karena; McAlea, Eamonn; Murphy, Finbarr; Tofail, Syed A M

The international dialogue on responsible governance of nanotechnologies engages a wide range of actors with conflicting as well as common interests. It is also characterised by a lack of evidence-based data on uncertain risks of in particular engineered nanomaterials. The present paper aims at deepening understanding of the collective decision making context at international level using the grounded theory approach as proposed by Glaser and Strauss in "The Discovery of Grounded Theory" (1967). This starts by discussing relevant concepts from different fields including sociological and political studies of international relations as well as political philosophy and ethics. This analysis of current trends in international law making is taken as starting point for exploring the role that a software decision support tool could play in multi-stakeholder global governance of nanotechnologies. These theoretical ideas are then compared with the current design of the SUN Decision Support System (SUNDS) under development in the European project on Sustainable Nanotechnologies (SUN, www.sun-fp7.eu). Through constant comparison, the ideas are also compared with requirements of different stakeholders as expressed during a user workshop. This allows for highlighting discussion points for further consideration.

An archival examination of environment and disease in eastern Africa in recent history

NASA Astrophysics Data System (ADS)

Larsen, L.

2012-04-01

In order to better understand present interactions between climate and infectious disease incidence it is important to examine the history of disease outbreaks and burdens, and their likely links with the environment. This paper will present research that is currently being undertaken on the identification and mapping of historic incidences of malaria, schistosomiasis and Rift Valley fever (RVF) in eastern Africa in relation to possible environmental, social, economic and political contributing factors. The research covers the past one hundred years or so and primarily draws on a range of archival documentary sources located in the region and the former imperial centres. The paper will discuss the methodologies employed in the building of a comprehensive historical database. The research is part of a larger EU FP7-funded project which aims to map, examine and anticipate the future risks of the three diseases in eastern Africa in response to environmental change. The paper will outline how the construction of such a historic database allows the contextualization of current climate-disease relationships and can thus contribute to discussions on the effects of changing climate on future disease trends.

Testing a new flux rope model using the HELCATS CME catalogue

NASA Astrophysics Data System (ADS)

Rouillard, Alexis Paul; Lavarra, Michael

2017-04-01

We present a magnetically-driven flux rope model that computes the forces acting on a twisted magnetic flux rope from the Sun to 1AU. This model assumes a more realistic flux rope geometry than assumed before by these types of models. The balance of force is computed in an analogous manner to the well-known Chen flux-rope model. The 3-D vector components of the magnetic field measured by a probe flying through the flux rope can be extracted for any flux rope orientation imposed near the Sun. We test this model through a parametric study and a systematic comparison of the model with the HELCATS catalogues (imagery and in situ). We also report on our investigations of other physical mechanisms such as the shift of flux-surfaces associated with the magnetic forces acting to accelerate the flux rope from the lower to upper corona. Finally, we present an evaluation of this model for space-weather predictions. This work was partly funded by the HELCATS project under the FP7 EU contract number 606692.

Empowering citizens in international governance of nanotechnologies

NASA Astrophysics Data System (ADS)

Malsch, Ineke; Subramanian, Vrishali; Semenzin, Elena; Hristozov, Danail; Marcomini, Antonio; Mullins, Martin; Hester, Karena; McAlea, Eamonn; Murphy, Finbarr; Tofail, Syed A. M.

2015-05-01

The international dialogue on responsible governance of nanotechnologies engages a wide range of actors with conflicting as well as common interests. It is also characterised by a lack of evidence-based data on uncertain risks of in particular engineered nanomaterials. The present paper aims at deepening understanding of the collective decision making context at international level using the grounded theory approach as proposed by Glaser and Strauss in "The Discovery of Grounded Theory" (1967). This starts by discussing relevant concepts from different fields including sociological and political studies of international relations as well as political philosophy and ethics. This analysis of current trends in international law making is taken as starting point for exploring the role that a software decision support tool could play in multi-stakeholder global governance of nanotechnologies. These theoretical ideas are then compared with the current design of the SUN Decision Support System (SUNDS) under development in the European project on Sustainable Nanotechnologies (SUN, www.sun-fp7.eu). Through constant comparison, the ideas are also compared with requirements of different stakeholders as expressed during a user workshop. This allows for highlighting discussion points for further consideration.

Oceanography at coastal scales: Introduction to the special issue on results from the EU FP7 FIELD_AC project

NASA Astrophysics Data System (ADS)

Sánchez-Arcilla, Agustín; Wolf, Judith; Monbaliu, Jaak

2014-09-01

The high-resolution and coupled forecasting of wind, waves and currents, in restricted coastal domains, offer a number of important challenges; these limit the quality of predictions, in the present state-of-the-art. This paper presents the main results obtained for such coastal domains, with reference to a variety of modelling suites and observing networks for: a) Liverpool Bay; b) German Bight; c) Gulf of Venice; and d) the Catalan coast. All of these areas are restricted domains, where boundary effects play a significant role in the resulting inner dynamics. This contribution addresses also the themes of the other papers in this Special Issue, ranging from observations to simulations. Emphasis is placed upon the physics controlling such restricted areas. The text deals also with the transfer to end-users and other interested parties, since the requirements on resolution, accuracy and robustness must be linked to their applications. Finally, some remarks are included on the way forward for coastal oceanography and the synergetic combination of in-situ and remote measurements, with high-resolution 3D simulations.

Experimentally simulating the dynamics of quantum light and matter at ultrastrong coupling using circuit QED (2) - light dynamics and light-matter entanglement -

NASA Astrophysics Data System (ADS)

Sagastizabal, R.; Langford, N. K.; Kounalakis, M.; Dickel, C.; Bruno, A.; Luthi, F.; Thoen, D. J.; Endo, A.; Dicarlo, L.

Light-matter interaction can lead to large photon build-up and hybrid atom-photon entanglement in the ultrastrong coupling (USC) regime, where the coupling strength becomes comparable to the eigenenergies of the system. Accessing the cavity degree of freedom, however, is an outstanding challenge in natural USC systems. In this talk, we directly probe light field dynamics in the USC regime using a digital simulation of the quantum Rabi model in a planar circuit QED chip with a transmon moderately coupled to a resonator. We produce high-accuracy USC light-matter dynamics, using second-order Trotterisation and up to 90 Trotter steps. We probe the average photon number, photon parity and perform Wigner tomography of the simulated field. Finally, we combine tomography of the resonator with qubit measurements to evidence the Schrödinger-cat-like atom-photon entanglement which is a key signature of light-matter dynamics in the USC regime. Funding from the EU FP7 Project ScaleQIT, the ERC Synergy Grant QC-lab, the Netherlands Organization of Scientic Research (NWO), and Microsoft Research.

Climate services in the tourism sector - examples and market research

NASA Astrophysics Data System (ADS)

Damm, Andrea; Köberl, Judith; Prettenthaler, Franz; Kortschak, Dominik; Hofer, Marianne; Winkler, Claudia

2017-04-01

Tourism is one of the most weather-sensitive sectors. Hence, dealing with weather and climate risks is an important part of operational risk management. WEDDA® (WEather Driven Demand Analysis), developed by Joanneum Research, represents a comprehensive and flexible toolbox for managing weather and climate risks. Modelling the demand for products or services of a particular economic sector or company and its weather and climate sensitivity usually forms the starting and central point of WEDDA®. Coupling the calibrated demand models to either long-term climate scenarios or short-term weather forecasts enables the use of WEDDA® for the following areas of application: (i) implementing short-term forecasting systems for the prediction of the considered indicator; (ii) quantifying the weather risk of a particular economic sector or company using parameters from finance (e.g. Value-at-Risk); (iii) assessing the potential impacts of changing climatic conditions on a particular economic sector or company. WEDDA® for short-term forecasts on the demand for products or services is currently used by various tourism businesses, such as open-air swimming pools, ski areas, and restaurants. It supports tourism and recreation facilities to better cope with (increasing) weather variability by optimizing the disposability of staff, resources and merchandise according to expected demand. Since coping with increasing weather variability forms one of the challenges with respect to climate change, WEDDA® may become an important component within a whole pool of weather and climate services designed to support tourism and recreation facilities to adapt to climate change. Climate change impact assessments at European scale, as conducted in the EU-FP7 project IMPACT2C, provide basic information of climate change impacts on tourism demand not only for individual tourism businesses, but also for regional and national tourism planners and policy makers interested in benchmarks for the vulnerability of their tourism destination. In this project we analysed the impacts of +2 °C global warming on winter tourism demand in ski tourism related regions in Europe. In order to achieve the climate targets, tailored climate information services - for individual businesses as well as at the regional and national level - play an important role. The current market, however, is still in the early stages. In the ongoing H2020 projects EU-MACS (www.eu-macs.eu) and MARCO (www.marco-h2020.eu) (Nov 2016 - Oct 2018) Joanneum Research explores the climate services market in the tourism sector. The current use of climate services is reviewed in detail and in an interactive process key market barriers and enablers will be identified in close collaboration with stakeholders from the tourism industry. The analysis and co-development of new climate services concepts for the tourism sector aims to reduce the gaps between climate services supply and demand.

New Efforts of The Cergop Data-bank At Graz For Cergop-2

NASA Astrophysics Data System (ADS)

Pesec, P.; Stangl, G.

Starting with 1994 Graz/Austria took over the task of providing a data-bank for storing and re-distributing Rinex data measured at all CEGRN stations. In view of the future project CERGOP-2/Environment submitted to EU (5. FP)several modifications are required in order to take into account near real-time data dissemi- nation and to consider a near real-time publication of certified CERGOP-2 products for scientific and public access via Internet, and for political decision making in case of eventual hazard prediction. Due to the interdisciplinarity of environmental research the contents of different other data-banks should be included. We will present an approach which should result in a seamless data-bank updated in near real-time and placing at disposal methodology, data, results as well as current informations on the ongoing projects and future developments.

Tissue microarrays and digital image analysis.

PubMed

Ryan, Denise; Mulrane, Laoighse; Rexhepaj, Elton; Gallagher, William M

2011-01-01

Tissue microarrays (TMAs) have recently emerged as very valuable tools for high-throughput pathological assessment, especially in the cancer research arena. This important technology, however, has yet to fully penetrate into the area of toxicology. Here, we describe the creation of TMAs representative of samples produced from conventional toxicology studies within a large-scale, multi-institutional pan-European project, PredTox. PredTox, short for Predictive Toxicology, formed part of an EU FP6 Integrated Project, Innovative Medicines for Europe (InnoMed), and aimed to study pre-clinically 16 compounds of known liver and/or kidney toxicity. In more detail, TMAs were constructed from materials corresponding to the full face sections of liver and kidney from rats treated with different drug candidates by members of the consortium. We also describe the process of digital slide scanning of kidney and liver sections, in the context of creating an online resource of histopathological data.

First-Year Students' Priorities and Choices in STEM Studies--IRIS Findings from Germany and Austria

ERIC Educational Resources Information Center

Elster, D.

2014-01-01

IRIS (Interests and Recruitment in Science; http://iris.fp-7.org/about-iris/) is a European 7th framework project focusing on the challenge that only few young people in general, and women in particular, choose an education and career in science and technology. Project IRIS aims to contribute to the improvement of recruitment, retention and gender…

EGO: Towards a global glider infrastructure for the benefit of marine research and operational oceanography

NASA Astrophysics Data System (ADS)

Testor, Pierre

2013-04-01

In the 1990 s, while gliders were being developed and successfully passing first tests, their potential use for ocean research started to be discussed in international conferences because they could help us improve the cost-effectiveness, sampling, and distribution of the ocean observations (see OceanObs'99 Conference Statement - UNESCO). After the prototype phase, in the 2000 s, one could only witness the growing glider activity throughout the world. The first glider experiments in Europe brought together several teams that were interested in the technology and a consortium formed naturally from these informal collaborations. Since 2006, Everyone's Gliding Observatories (EGO - http://www.ego-network.org) Workshops and Glider Schools have been organized, whilst becoming the international forum for glider activities. Some key challenges have emerged from the expansion of the glider system and require now setting up a sustainable European as well as a global system to operate glider and to ensure a smooth and sustained link to the Global Ocean Observing System (GOOS). Glider technology faces many scientific, technological and logistical issues. In particular, it approaches the challenge of controlling many steerable probes in a variable environment for better sampling. It also needs the development of new formats and procedures in order to build glider observatories at a global level. Several geographically distributed teams of oceanographers now operate gliders, and there is a risk of fragmentation. We will here present results from our consortium who intends to solve most of these issues through scientific and technological coordination and networking. This approach is supported by the ESF through Cooperation in the field of Scientific and Technical Research (COST). The COST Action ES0904 "EGO" started in July 2010 aiming to build international cooperation and capacities at the scientific, technological, and organizational levels, for sustained observations of the oceans with gliders. A major impact of this Action was the elaboration of the EU Collaborative Project GROOM, Gliders for Research, Ocean Observation and Management for the FP7 call "Capacities - Research Infrastructures", which addresses the topic "design studies for research infrastructures in all S&T fields" (see http://www.groom-fp.eu).

Vanadium dioxide thin films prepared on silicon by low temperature MBE growth and ex-situ annealing

NASA Astrophysics Data System (ADS)

Homm, Pia; van Bilzen, Bart; Menghini, Mariela; Locquet, Jean-Pierre; Ivanova, Todora; Sanchez, Luis; Sanchis, Pablo

Vanadium dioxide (VO2) is a material that shows an insulator to metal transition (IMT) near room temperature. This property can be exploited for applications in field effect devices, electro-optical switches and nonlinear circuit components. We have prepared VO2 thin films on silicon wafers by combining a low temperature MBE growth with an ex-situ annealing at high temperature. We investigated the structural, electrical and optical characteristics of films with thicknesses ranging from 10 to 100 nm. We have also studied the influence of the substrate cleaning. The films grown with our method are polycrystalline with a preferred orientation in the (011) direction of the monoclinic phase. For the films produced on silicon with a native oxide, an IMT at around 75 °C is observed. The magnitude of the resistance change across the IMT decreases with thickness while the refractive index at room temperature corresponds with values reported in the literature for thin films. The successful growth of VO2 films on silicon with good electrical and optical properties is an important step towards the integration of VO2 in novel devices. The authors acknowledge financial support from the FWO project G052010N10 and EU-FP7 SITOGA project. PH acknowledges support from Becas Chile - CONICYT.

Super-cooled liquid water topped sub-arctic clouds and precipitation - investigation based on combination of ground-based in-situ and remote-sensing observations

NASA Astrophysics Data System (ADS)

Hirsikko, Anne; Brus, David; O'Connor, Ewan J.; Filioglou, Maria; Komppula, Mika; Romakkaniemi, Sami

2017-04-01

In the high and mid latitudes super-cooled liquid water layers are frequently observed on top of clouds. These layers are difficult to forecast with numerical weather prediction models, even though, they have strong influence on atmospheric radiative properties, cloud microphysical properties, and subsequently, precipitation. This work investigates properties of super-cooled liquid water layer topped sub-arctic clouds and precipitation observed with ground-based in-situ (cloud probes) and remote-sensing (a cloud radar, Doppler and multi-wavelength lidars) instrumentation during two-month long Pallas Cloud Experiment (PaCE 2015) in autumn 2015. Analysis is based on standard Cloudnet scheme supplemented with new retrieval products of the specific clouds and their properties. Combination of two scales of observation provides new information on properties of clouds and precipitation in the sub-arctic Pallas region. Current status of results will be presented during the conference. The authors acknowledge financial support by the Academy of Finland (Centre of Excellence Programme, grant no 272041; and ICINA project, grant no 285068), the ACTRIS2 - European Union's Horizon 2020 research and innovation programme under grant agreement No 654109, the KONE foundation, and the EU FP7 project BACCHUS (grant no 603445).

X-ray Radiative Transfer in Protoplanetary Disks with ProDiMo

NASA Astrophysics Data System (ADS)

Rab, Christian; Woitke, Peter; Güdel, Manuel; Min, Michiel; Diana Team

2013-07-01

X-ray emission is a common property of YSOs. T Tauri stars show X-ray luminosities up to 10^32 erg/s but also Herbig Ae/Be stars can have moderate X-ray emission in the range of 10^28 to 10^31 erg/s. We want to investigate the impact of X-ray radiation on the thermal and chemical structure of protoplanetary discs around these YSOs. Therefore we have added a new X-ray Radiative Transfer module to the radiation thermo-chemical code ProDiMo (Protoplanetary Disc Modeling) extending the existing implementation of X-ray chemistry implemented by Aresu et al. This new module considers gas and dust opacities (including scattering) and a possible X-ray background field. Further we added a new set of FUV - photoreactions to the X-ray chemistry module of ProDiMo as fast electrons created in X-ray ionisation can produce a significant secondary FUV radiation field by exciting atomic or molecular hydrogen. We discuss the importance of these processes on the thermal and chemical structure of the protoplanetary disc, and present them on the basis of a typical T Tauri disc model. This work is performed in the context of the EU FP7-project DIANA (www.diana-project.com).

Application and Validation of a GIS Model for Local Tsunami Vulnerability and Mortality Risk Analysis

NASA Astrophysics Data System (ADS)

Harbitz, C. B.; Frauenfelder, R.; Kaiser, G.; Glimsdal, S.; Sverdrup-thygeson, K.; Løvholt, F.; Gruenburg, L.; Mc Adoo, B. G.

2015-12-01

The 2011 Tōhoku tsunami caused a high number of fatalities and massive destruction. Data collected after the event allow for retrospective analyses. Since 2009, NGI has developed a generic GIS model for local analyses of tsunami vulnerability and mortality risk. The mortality risk convolves the hazard, exposure, and vulnerability. The hazard is represented by the maximum tsunami flow depth (with a corresponding likelihood), the exposure is described by the population density in time and space, while the vulnerability is expressed by the probability of being killed as a function of flow depth and building class. The analysis is further based on high-resolution DEMs. Normally a certain tsunami scenario with a corresponding return period is applied for vulnerability and mortality risk analysis. Hence, the model was first employed for a tsunami forecast scenario affecting Bridgetown, Barbados, and further developed in a forecast study for the city of Batangas in the Philippines. Subsequently, the model was tested by hindcasting the 2009 South Pacific tsunami in American Samoa. This hindcast was based on post-tsunami information. The GIS model was adapted for optimal use of the available data and successfully estimated the degree of mortality.For further validation and development, the model was recently applied in the RAPSODI project for hindcasting the 2011 Tōhoku tsunami in Sendai and Ishinomaki. With reasonable choices of building vulnerability, the estimated expected number of fatalities agree well with the reported death toll. The results of the mortality hindcast for the 2011 Tōhoku tsunami substantiate that the GIS model can help to identify high tsunami mortality risk areas, as well as identify the main risk drivers.The research leading to these results has received funding from CONCERT-Japan Joint Call on Efficient Energy Storage and Distribution/Resilience against Disasters (http://www.concertjapan.eu; project RAPSODI - Risk Assessment and design of Prevention Structures fOr enhanced tsunami DIsaster resilience http://www.ngi.no/en/Project-pages/RAPSODI/), and from the European Union's Seventh Framework Programme (FP7/2007-2013) under grant agreement n° 603839 (Project ASTARTE - Assessment, STrategy And Risk reduction for Tsunamis in Europe http://www.astarte-project.eu/).

The Priority position paper: Protecting Europe's food chain from prions.

PubMed

Requena, Jesús R; Kristensson, Krister; Korth, Carsten; Zurzolo, Chiara; Simmons, Marion; Aguilar-Calvo, Patricia; Aguzzi, Adriano; Andreoletti, Olivier; Benestad, Sylvie L; Böhm, Reinhard; Brown, Karen; Calgua, Byron; Del Río, José Antonio; Espinosa, Juan Carlos; Girones, Rosina; Godsave, Sue; Hoelzle, Ludwig E; Knittler, Michael R; Kuhn, Franziska; Legname, Giuseppe; Laeven, Paul; Mabbott, Neil; Mitrova, Eva; Müller-Schiffmann, Andreas; Nuvolone, Mario; Peters, Peter J; Raeber, Alex; Roth, Klaus; Schmitz, Matthias; Schroeder, Björn; Sonati, Tiziana; Stitz, Lothar; Taraboulos, Albert; Torres, Juan María; Yan, Zheng-Xin; Zerr, Inga

2016-05-03

Bovine spongiform encephalopathy (BSE) created a global European crisis in the 1980s and 90s, with very serious health and economic implications. Classical BSE now appears to be under control, to a great extent as a result of a global research effort that identified the sources of prions in meat and bone meal (MBM) and developed new animal-testing tools that guided policy. Priority ( www.prionpriority.eu ) was a European Union (EU) Framework Program 7 (FP7)-funded project through which 21 European research institutions and small and medium enterprises (SMEs) joined efforts between 2009 and 2014, to conduct coordinated basic and applied research on prions and prion diseases. At the end of the project, the Priority consortium drafted a position paper ( www.prionpriority.eu/Priority position paper) with its main conclusions. In the present opinion paper, we summarize these conclusions. With respect to the issue of re-introducing ruminant protein into the feed-chain, our opinion is that sustaining an absolute ban on feeding ruminant protein to ruminants is essential. In particular, the spread and impact of non-classical forms of scrapie and BSE in ruminants is not fully understood and the risks cannot be estimated. Atypical prion agents will probably continue to represent the dominant form of prion diseases in the near future in Europe. Atypical L-type BSE has clear zoonotic potential, as demonstrated in experimental models. Similarly, there are now data indicating that the atypical scrapie agent can cross various species barriers. More epidemiological data from large cohorts are necessary to reach any conclusion on the impact of its transmissibility on public health. Re-evaluations of safety precautions may become necessary depending on the outcome of these studies. Intensified searching for molecular determinants of the species barrier is recommended, since this barrier is key for important policy areas and risk assessment. Understanding the structural basis for strains and the basis for adaptation of a strain to a new host will require continued fundamental research, also needed to understand mechanisms of prion transmission, replication and how they cause nervous system dysfunction and death. Early detection of prion infection, ideally at a preclinical stage, also remains crucial for development of effective treatment strategies.

The Priority position paper: Protecting Europe's food chain from prions

PubMed Central

Kristensson, Krister; Korth, Carsten; Zurzolo, Chiara; Simmons, Marion; Aguilar-Calvo, Patricia; Aguzzi, Adriano; Andreoletti, Olivier; Benestad, Sylvie L.; Böhm, Reinhard; Brown, Karen; Calgua, Byron; del Río, José Antonio; Espinosa, Juan Carlos; Girones, Rosina; Godsave, Sue; Hoelzle, Ludwig E.; Knittler, Michael R.; Kuhn, Franziska; Legname, Giuseppe; Laeven, Paul; Mitrova, Eva; Müller-Schiffmann, Andreas; Nuvolone, Mario; Peters, Peter J.; Raeber, Alex; Roth, Klaus; Schmitz, Matthias; Schroeder, Björn; Sonati, Tiziana; Stitz, Lothar; Taraboulos, Albert; Torres, Juan María; Yan, Zheng-Xin; Zerr, Inga

2016-01-01

ABSTRACT Bovine spongiform encephalopathy (BSE) created a global European crisis in the 1980s and 90s, with very serious health and economic implications. Classical BSE now appears to be under control, to a great extent as a result of a global research effort that identified the sources of prions in meat and bone meal (MBM) and developed new animal-testing tools that guided policy. Priority (www.prionpriority.eu) was a European Union (EU) Framework Program 7 (FP7)-funded project through which 21 European research institutions and small and medium enterprises (SMEs) joined efforts between 2009 and 2014, to conduct coordinated basic and applied research on prions and prion diseases. At the end of the project, the Priority consortium drafted a position paper (www.prionpriority.eu/Priority position paper) with its main conclusions. In the present opinion paper, we summarize these conclusions. With respect to the issue of re-introducing ruminant protein into the feed-chain, our opinion is that sustaining an absolute ban on feeding ruminant protein to ruminants is essential. In particular, the spread and impact of non-classical forms of scrapie and BSE in ruminants is not fully understood and the risks cannot be estimated. Atypical prion agents will probably continue to represent the dominant form of prion diseases in the near future in Europe. Atypical L-type BSE has clear zoonotic potential, as demonstrated in experimental models. Similarly, there are now data indicating that the atypical scrapie agent can cross various species barriers. More epidemiological data from large cohorts are necessary to reach any conclusion on the impact of its transmissibility on public health. Re-evaluations of safety precautions may become necessary depending on the outcome of these studies. Intensified searching for molecular determinants of the species barrier is recommended, since this barrier is key for important policy areas and risk assessment. Understanding the structural basis for strains and the basis for adaptation of a strain to a new host will require continued fundamental research, also needed to understand mechanisms of prion transmission, replication and how they cause nervous system dysfunction and death. Early detection of prion infection, ideally at a preclinical stage, also remains crucial for development of effective treatment strategies. PMID:27220820

Change detection over Sokolov open-pit mining area, Czech Republic, using multi-temporal HyMAP data (2009-2010)

NASA Astrophysics Data System (ADS)

Adar, S.; Notesco, G.; Brook, A.; Livne, I.; Rojik, P.; Kopacková, V.; Zelenkova, K.; Misurec, J.; Bourguignon, A.; Chevrel, S.; Ehrler, C.; Fisher, C.; Hanus, J.; Shkolnisky, Y.; Ben Dor, E.

2011-11-01

Two HyMap images acquired over the same lignite open-pit mining site in Sokolov, Czech Republic, during the summers of 2009 and 2010 (12 months apart), were investigated in this study. The site selected for this research is one of three test sites (the others being in South Africa and Kyrgyzstan) within the framework of the EO-MINERS FP7 Project (http://www.eo-miners.eu). The goal of EO-MINERS is to "integrate new and existing Earth Observation tools to improve best practice in mining activities and to reduce the mining related environmental and societal footprint". Accordingly, the main objective of the current study was to develop hyperspectral-based means for the detection of small spectral changes and to relate these changes to possible degradation or reclamation indicators of the area under investigation. To ensure significant detection of small spectral changes, the temporal domain was investigated along with careful generation of reflectance information. Thus, intensive spectroradiometric ground measurements were carried out to ensure calibration and validation aspects during both overflights. The performance of these corrections was assessed using the Quality Indicators setup developed under a different FP7 project-EUFAR (http://www.eufar.net), which helped select the highest quality data for further work. This approach allows direct distinction of the real information from noise. The reflectance images were used as input for the application of spectral-based change-detection algorithms and indices to account for small and reliable changes. The related algorithms were then developed and applied on a pixel-by-pixel basis to map spectral changes over the space of a year. Using field spectroscopy and ground truth measurements on both overpass dates, it was possible to explain the results and allocate spatial kinetic processes of the environmental changes during the time elapsed between the flights. It was found, for instance, that significant spectral changes are capable of revealing mineral processes, vegetation status and soil formation long before these are apparent to the naked eye. Further study is being conducted under the above initiative to extend this approach to other mining areas worldwide and to improve the robustness of the developed algorithm.

Quality and clinical supply considerations of Paediatric Investigation Plans for IV preparations-A case study with the FP7 CloSed project.

PubMed

Hanning, Sara M; Orlu Gul, Mine; Winslade, Jackie; Baarslag, Manuel A; Neubert, Antje; Tuleu, Catherine

2016-09-25

A Paediatric Investigation Plan (PIP) is a development plan that aims to ensure that sufficient data are obtained through studies in paediatrics to support the generation of marketing authorisation of medicines for children. This paper highlights some practical considerations and challenges with respect to PIP submissions and paediatric clinical trials during the pharmaceutical development phase, using the FP7-funded Clonidine for Sedation of Paediatric Patients in the Intensive Care Unit (CloSed) project as a case study. Examples discussed include challenges and considerations regarding formulation development, blinding and randomisation, product labelling and shipment and clinical trial requirements versus requirements for marketing authorisation. A significant quantity of information is required for PIP submissions and it is hoped that future applicants may benefit from an insight into some critical considerations and challenges faced in the CloSed project. Copyright © 2016 Elsevier B.V. All rights reserved.

LAGUNA DESIGN STUDY, Underground infrastructures and engineering

NASA Astrophysics Data System (ADS)

Nuijten, Guido Alexander

2011-07-01

The European Commission has awarded the LAGUNA project a grant of 1.7 million euro for a Design Study from the seventh framework program of research and technology development (FP7-INFRASTRUCTURES - 2007-1) in 2008. The purpose of this two year work is to study the feasibility of the considered experiments and prepare a conceptual design of the required underground infrastructure. It is due to deliver a report that allows the funding agencies to decide on the realization of the experiment and to select the site and the technology. The result of this work is the first step towards fulfilling the goals of LAGUNA. The work will continue with EU funding to study the possibilities more thoroughly. The LAGUNA project is included in the future plans prepared by European funding organizations. (Astroparticle physics in Europe). It is recommended that a new large European infrastructure is put forward, as a future international multi-purpose facility for improved studies on proton decay and low-energy neutrinos from astrophysical origin. The three detection techniques being studied for such large detectors in Europe, Water-Cherenkov (like MEMPHYS), liquid scintillator (like LENA) and liquid argon (like GLACIER), are evaluated in the context of a common design study which should also address the underground infrastructure and the possibility of an eventual detection of future accelerator neutrino beams. The design study is also to take into account worldwide efforts and converge, on a time scale of 2010, to a common proposal.

The climate4impact platform: Providing, tailoring and facilitating climate model data access

NASA Astrophysics Data System (ADS)

Pagé, Christian; Pagani, Andrea; Plieger, Maarten; Som de Cerff, Wim; Mihajlovski, Andrej; de Vreede, Ernst; Spinuso, Alessandro; Hutjes, Ronald; de Jong, Fokke; Bärring, Lars; Vega, Manuel; Cofiño, Antonio; d'Anca, Alessandro; Fiore, Sandro; Kolax, Michael

2017-04-01

One of the main objectives of climate4impact is to provide standardized web services and tools that are reusable in other portals. These services include web processing services, web coverage services and web mapping services (WPS, WCS and WMS). Tailored portals can be targeted to specific communities and/or countries/regions while making use of those services. Easier access to climate data is very important for the climate change impact communities. To fulfill this objective, the climate4impact (http://climate4impact.eu/) web portal and services has been developed, targeting climate change impact modellers, impact and adaptation consultants, as well as other experts using climate change data. It provides to users harmonized access to climate model data through tailored services. It features static and dynamic documentation, Use Cases and best practice examples, an advanced search interface, an integrated authentication and authorization system with the Earth System Grid Federation (ESGF), a visualization interface with ADAGUC web mapping tools. In the latest version, statistical downscaling services, provided by the Santander Meteorology Group Downscaling Portal, were integrated. An innovative interface to integrate statistical downscaling services will be released in the upcoming version. The latter will be a big step in bridging the gap between climate scientists and the climate change impact communities. The climate4impact portal builds on the infrastructure of an international distributed database that has been set to disseminate the results from the global climate model results of the Coupled Model Intercomparison project Phase 5 (CMIP5). This database, the ESGF, is an international collaboration that develops, deploys and maintains software infrastructure for the management, dissemination, and analysis of climate model data. The European FP7 project IS-ENES, Infrastructure for the European Network for Earth System modelling, supports the European contribution to ESGF and contributes to the ESGF open source effort, notably through the development of search, monitoring, quality control, and metadata services. In its second phase, IS-ENES2 supports the implementation of regional climate model results from the international Coordinated Regional Downscaling Experiments (CORDEX). These services were extended within the European FP7 Climate Information Portal for Copernicus (CLIPC) project, and some could be later integrated into the European Copernicus platform.

Floor plate chemoattracts crossed axons and chemorepels uncrossed axons in the vertebrate brain.

PubMed

Tamada, A; Shirasaki, R; Murakami, F

1995-05-01

In the bilaterally symmetrical vertebrate CNS, all developing axons must choose between remaining on the same side of the midline or growing across it. The mechanism underlying this axonal pathfinding is, however, poorly understood. Here we demonstrate that the ventral midline floor plate (FP) chemorepels two types of ipsilaterally projecting axons, one from the alar plate and another from the basal plate in the mesencephalon. We further demonstrate that the FP chemoattracts contralaterally projecting myelencephalic as well as metencephalic axons. The FP at all axial levels displayed both chemoattractive and chemorepellent activities, suggesting that FP chemoattraction and chemorepulsion may be at work throughout the neuraxis. Chemotropic guidance by the FP may therefore play a key role in the establishment of neuronal projection laterality.

Managed Aquifer Recharge in Italy: present and prospects.

NASA Astrophysics Data System (ADS)

Rossetto, Rudy

2015-04-01

On October the 3rd 2014, a one-day Workshop on Managed Aquifer Recharge (MAR) experiences in Italy took place at the GEOFLUID fair in Piacenza. It was organized within the framework of the EIP AG 128 - MAR Solutions - Managed Aquifer Recharge Strategies and Actions and the EU FPVII MARSOL. The event aimed at showcasing present experiences on MAR in Italy while at the same time starting a network among all the Institutions involved. In this contribution, we discuss the state of MAR application in Italy and summarize the outcomes of that event. In Italy aquifer recharge is traditionally applied unintentionally, by increasing riverbank filtration or because of excess irrigation. A certain interest for artificial recharge of aquifers arose at the end of the '70s and the beginning of the '80s and tests have been carried out in Tuscany, Veneto and Friuli Venezia Giulia. During the last years some projects on aquifer recharge were co-financed by the European Commission mainly through the LIFE program. Nearly all of them use the terminology of artificial recharge instead of MAR. They are: - TRUST (Tool for regional - scale assessment of groundwater storage improvement in adaptation to climate change, LIFE07 ENV/IT/000475; Marsala 2014); - AQUOR (Implementation of a water saving and artificial recharging participated strategy for the quantitative groundwater layer rebalance of the upper Vicenza's plain - LIFE 2010 ENV/IT/380; Mezzalira et al. 2014); - WARBO (Water re-born - artificial recharge: innovative technologies for the sustainable management of water resources, LIFE10 ENV/IT/000394; 2014). While the TRUST project dealt in general with aquifer recharge, AQUOR and WARBO focused essentially on small scale demonstration plants. Within the EU FPVII-ENV-2013 MARSOL project (Demonstrating Managed Aquifer Recharge as a Solution to Water Scarcity and Drought; 2014), a dedicated monitoring and decision support system is under development to manage recharge at a large scale riverbank filtration plant, worth 15 Mm3/year in Lucca (Tuscany; Borsi et al. 2014). In 2014, the Regional Authority of Emilia Romagna started a pilot on the Marecchia River fan using a recharge basin to alleviate water scarcity in the Rimini area as results of drought periods (Severi et al. 2014). To apply MAR techniques on a large scale is of particular interest the possibility to allow farmer's associations or drainage consortiums to play an important role in storing excess rainfall water in aquifers. Few hectares of land in rural areas may be dedicated to MAR plants, transforming a traditionally water consumer sector in one preserving it - opportunities are then linked to the provision of water related ecosystem services. Aquifer recharge is allowed in Italy only since September 2013, but still a regulatory framework is missing. Hopefully, this regulatory scheme will benefit from previous and on-going experiences. Dissemination of MAR scientific findings and technical know-how among governing authorities and the general public is crucial for the application of MAR techniques. Fundings for setting up new MAR plants may be available at national level. At the same time, lack of knowledge at intermediate governing bodies level is preventing the application of these techniques (i.e. building of small dams is favored although less convenient by several points of view in respect of MAR plants). Finally, it is of outmost importance to define which are the financial instruments to sustain these water infrastructures, so to guarantee not only their set up, but also routinely operations, opening as such a new market in the water sector. Acknowledgments This paper is co-financed within the framework of the EU FP7-ENV-2013-WATER-INNO-DEMO MARSOL (Grant Agreement n. 619120). References Borsi, I., Mazzanti, G., Barbagli, A., Rossetto, R., 2014. The riverbank filtration plant in S. Alessio (Lucca): monitoring and modeling activity within EU the FP7 MARSOL project. Acque Sotterranee - Italian Journal of Groundwater, Vol. 3, n. 3/137 Marsala, V. (2014). LIFE+ TRUST project: tool to assist the implementation of the Framework Directive 2000/60/CE, methodology and results. Acque Sotterranee - Italian Journal of Groundwater, Vol. 3, n. 3/137 MARSOL (2014). Demonstrating Managed Aquifer Recharge as a Solution to Water Scarcity and Drought www.marsol.eu [accessed 4 January 2015] Mezzalira, G., Niceforo, U., Gusmaroli, G. (2014). Forested infiltration areas (FIA); principles, experiences, perspectives. Acque Sotterranee - Italian Journal of Groundwater, Vol. 3, n. 3/137 Severi, P., Bonzi, L., Ferrari, V., Pellegrino, I. (2014). Managed aquifer recharge in the Marecchia alluvial fan (Rimini - Italy), start of the test and first results. Acque Sotterranee - Italian Journal of Groundwater, Vol. 3, n. 3/137 WARBO, 2014. WATER RE-BORN - Artificial Recharge. Innovative Technologies for the Sustainable Management of Water Resources. http://www.warbo-life.eu/ [accessed 8 August 2014

An Integrated Data-Driven Strategy for Safe-by-Design Nanoparticles: The FP7 MODERN Project.

PubMed

Brehm, Martin; Kafka, Alexander; Bamler, Markus; Kühne, Ralph; Schüürmann, Gerrit; Sikk, Lauri; Burk, Jaanus; Burk, Peeter; Tamm, Tarmo; Tämm, Kaido; Pokhrel, Suman; Mädler, Lutz; Kahru, Anne; Aruoja, Villem; Sihtmäe, Mariliis; Scott-Fordsmand, Janeck; Sorensen, Peter B; Escorihuela, Laura; Roca, Carlos P; Fernández, Alberto; Giralt, Francesc; Rallo, Robert

2017-01-01

The development and implementation of safe-by-design strategies is key for the safe development of future generations of nanotechnology enabled products. The safety testing of the huge variety of nanomaterials that can be synthetized is unfeasible due to time and cost constraints. Computational modeling facilitates the implementation of alternative testing strategies in a time and cost effective way. The development of predictive nanotoxicology models requires the use of high quality experimental data on the structure, physicochemical properties and bioactivity of nanomaterials. The FP7 Project MODERN has developed and evaluated the main components of a computational framework for the evaluation of the environmental and health impacts of nanoparticles. This chapter describes each of the elements of the framework including aspects related to data generation, management and integration; development of nanodescriptors; establishment of nanostructure-activity relationships; identification of nanoparticle categories; hazard ranking and risk assessment.

Building a multidisciplinary e-infrastructure for the NextData Community

NASA Astrophysics Data System (ADS)

Nativi, Stefano; Rorro, Marco; Mazzetti, Paolo; Fiameni, Giuseppe; Papeschi, Fabrizio; Carpenè, Michele

2014-05-01

In 2012, Italy decided to launch a national initiative called NextData (http://www.nextdataproject.it/): a national system for the retrieval, storage, access and diffusion of environmental and climate data from mountain and marine areas. NextData is funded by the Research and University Ministry, as a "Project of Interest". In 2013, NextData funded a "special project", the NextData System of Systems Infrastructure project (ND-SoS-Ina). The main objective is to design, build and operate in production the NextData multidisciplinary and multi-organizational e-infrastructure for the publication and sharing of its resources (e.g. data, services, vocabularies, models). SoS-Ina realizes the NextData general portal implementing the interoperability among the data archives carried out by NextData. The Florentine Division of the Institute of Atmospheric Pollution Research of CNR (CNR-IIA) and CINECA run the project. SoS-Ina (http://essi-lab.eu/nextdata/sosina/) decided to adopt a "System of Systems" (SoS) approach based on a brokering architecture. This has been pursued by applying the brokering technology first developed by the EC-FP7 EuroGEOSS project (http://www.eurogeoss.eu/broker/Pages/AbouttheEuroGEOSSBroker.aspx) and more recently consolidated by the international programme GEOSS (Global Earth Observation System of Systems) of GEO (Group oh Earth Observation) -see http://www.earthobservations.org/documents/geo_ix/20111122_geoss_implementation_highlights.pdf. The NextData general Portal architecture definition will proceed accordingly with the requirements elicited by user communities. The portal will rely on services and interfaces being offered by the brokering middleware and will be based on Liferay (http://www.liferay.com/). Liferay is free and open source, it provides many built-in applications for social collaboration, content and document management. Liferay is also configurable for high availability. The project considers three distinct phases and related milestones: (a) the first prototype of the NextData SoS infrastructure, implementing the core functionalities; (b) the consolidated version of the NextData SoS infrastructure, implementing advanced functionalities; (c) the final and operative NextData SoS infrastructure for data and information sharing and publication. An important outcome of the project will be the performances and scalability advancement of the current brokering and portal technologies, exploiting resources and middleware services provided by CINECA.

Land degradation in the Canyoles river watershed, Eastern Spain

NASA Astrophysics Data System (ADS)

Cerdà, A.; Gonzalez Peñaloza, F. A.; Imeson, A. C.; Gimenez Morera, A.

2012-04-01

Human induced Land Degradation by actions that have a negative impact on the functioning of the environment (Imeson, 2012). Mediterranean arid lands have been intensely transformed by human activity through history, especially due to agricultural management. This intense use of the land resulted in a new man made landscape that is evolving as a consequence of the global change to a new situation that can trigger Land Degradation processes. Extensive areas of olive groves, fruit orchards and vineyards, many of them grown on marginal areas (e.g., terraced slopes) as well as non-sustainable land uses have induced different environmental problems in the Canyoles river watershed (Eastern Spain). The human and physical changes suffered by this region are being used as a representative area of the western Mediterranean basin to monitor how the responses to the Desertification and Land Degradation fit. The aim of this research is to evaluate socio-ecological systems as a part of the Land Ecosystem and Degradation Desertification Response Assessment (LEDDRA) project. This presentation will show the main Land Degradation processes that has been identified: [1] soil erosion as a consequence of agriculture, [2] soil compaction due to herbicide and heavy machinery use, [3] soil sealing on croplands due to heavy vehicles and asphalt and concrete application on roads, [4] soil/water pollution due to agrochemicals, [5] reduction of biodiversity in croplands due to herbicides and substitution of the traditional irrigation system, [6] urbanization processes of rural areas due to the development of urban areas and agricultural infrastructures, [7] monoculture of citrus plantations in the lower part of the watershed, [8] roads and railway construction, [9] aquifer depletion, [10] abandonment of industrial activities, [11] abandonment of local traditional practices for food production and other resources and [12] the effect of land abandonment and wildfires in the nearby mountainous areas on soil erosion and degradation processes. Special attention is being paid to the citrus plantations expansion at the Canyoles river watershed as it was found the increase in soil erosion is due to the chemically managed citrus orchards (Cerdà et al., 2009). The economic changes on the citrus orchards are also analized. This research is being conducted by the EU project "Land and Ecosystem Degradation and Desertification: Assessing the Fit of Responses" LEDDRA 243857 CONSORTIUM AGREEMENT . TR07 - VII PROGRAMA MARCO - ENERGÍA FP7-ENERGY-2007-2-TREN. - European Union FP7. ENV.2009 243857. The experimental setup within the citrus plantation is being supported by the the research project CGL2008-02879/BTE

Contingency planning for Phytophthora ramorum outbreaks: progress report work package 7, EU RAPRA project

Treesearch

M.H.C.G. Steeghs

2008-01-01

As part of the EU project ?Risk analysis for Phytophthora ramorum, a recently recognised pathogen threat to Europe and the cause of Sudden Oak Death in the USA? (acronym RAPRA) outbreak scenarios are defined and existing strategies for eradication and containment of Phytophthora ramorum evaluated. Based on the current knowledge...

An analysis of European riverine flood risk and adaptation measures under projected climate change

NASA Astrophysics Data System (ADS)

Bouwer, Laurens; Burzel, Andreas; Holz, Friederike; Winsemius, Hessel; de Bruijn, Karind

2015-04-01

There is increasing need to assess costs and benefits of adaptation at scales beyond the river basin. In Europe, such estimates are required at the European scale in order to set priorities for action and financing, for instance in the context of the EU Adaptation Strategy. The goal of this work as part of the FP7 BASE project is to develop a flood impact model that can be applied at Pan-European scale and that is able to project changes in flood risk due to climate change and socio-economic developments, and costs of adaptation. For this research, we build upon the global flood hazard estimation method developed by Winsemius et al. (Hydrology and Earth System Sciences, 2013), that produces flood inundation maps at different return period, for present day (EU WATCH) and future climate (IPCC scenarios RCP4.5 and 8.5, for five climate models). These maps are used for the assessment of flood impacts. We developed and tested a model for assessing direct economic flood damages by using large scale land use maps. We characterise vulnerable land use functions, in particular residential, commercial, industrial, infrastructure and agriculture, using depth-damage relationships. Furthermore, we apply up to NUTS3 level information on Gross Domestic Product, which is used as a proxy for relative differences in maximum damage values between different areas. Next, we test two adaptation measures, by adjusting flood protection levels and adjusting damage functions. The results show the projected changes in flood risk in the future. For example, on NUTS2 level, flood risk increases in some regions up to 179% (between the baseline scenario 1960-1999 and time slice 2010-2049). On country level there are increases up to 60% for selected climate models. The conference presentation will show the most relevant improvements in damage modelling on the continental scale, and results of the analysis of adaptation measures. The results will be critically discussed under the aspect of major uncertainties in both future flood hazards as well as damage costs and adaptation effects and costs.

Experimental and theoretical analysis for improved microscope design of optical projection tomographic microscopy.

PubMed

Coe, Ryan L; Seibel, Eric J

2013-09-01

We present theoretical and experimental results of axial displacement of objects relative to a fixed condenser focal plane (FP) in optical projection tomographic microscopy (OPTM). OPTM produces three-dimensional, reconstructed images of single cells from two-dimensional projections. The cell rotates in a microcapillary to acquire projections from different perspectives where the objective FP is scanned through the cell while the condenser FP remains fixed at the center of the microcapillary. This work uses a combination of experimental and theoretical methods to improve the OPTM instrument design.

Fingerprints and cardiovascular risk. The San Valentino fingerprint vascular screening project (SanVal/FP).

PubMed

Belcaro, G; Cesarone, M R; Ledda, A; Cornelli, U; Dugall, M; Di Renzo, A; Hosoi, M; Stuard, S; Vinciguerra, G; Pellegrini, L; Gizzi, G

2008-10-01

Fingerprints (FP), characteristic of humans, are impressions due to skin marks (ridges) on fingertips. Ridges are present on fingers/hands forming curved lines of different sizes/patterns. The point where a line stops or splits is defined typica' (their number/amount constitute identification patterns). FP are permanent and unique. This study compared FP patterns with cardiovascular risk factors: 7 main types of FP were used: 1. Arch: lines form waves from one site to the other side. 2. Tentarch: like arches but with a rising stick in the middle. 3. Loop: lines coming from one site returning in the middle to the same site. 4. Double loop: like loops but with two loops inside: one standing, one hanging. 5. Pocked loop: like the loop but with a small circle in the turning point. 6. Whorl: lines make circles. 7. Mixed figure: composed of different figures. There are two kinds of real typica: A. Ending line; B. Splitting lines (bifurcations). Several combinations may result. Ultrasound evaluation of carotid/femoral arteries in asymptomatic subjects. Arteries were evaluated with high-resolution ultrasound at the bifurcations. Four classes were defined: 1: normal intima-media (IMT) complex; 2: IMT thickening; 3: non-stenosing plaques (<50% stenosis); 4: stenosing plaque (>50%). Subjects in classes 1, 2, 3 were included into the analysis made comparing FP patterns and ultrasound. For each FP pattern: A. the main proportion of subjects with cardiovacular risk factors (91%) had arches (41.2%) and loops (either single, 38.2% or double 11.7% for a total of 49.9%). B. The remaining classes were statistically less important. C. The number of ridges per square mm was comparable in all pattern classes. D. The analysis of typica and other ridges characteristics requires a more elaborated system. Future research must define simple, low cost screening methods for preselection of subjects at higher cardiovascular risk or for exclusion of low risk subjects. The evaluation of fingerprint pattern may be useful to define risk groups.

Enabling Interoperability in Heliophysical Domains

NASA Astrophysics Data System (ADS)

Bentley, Robert

2013-04-01

There are many aspects of science in the Solar System that are overlapping - phenomena observed in one domain can have effects in other domains. However, there are many problems related to exploiting the data in cross-disciplinary studies because of lack of interoperability of the data and services. The CASSIS project is a Coordination Action funded under FP7 that has the objective of improving the interoperability of data and services related Solar System science. CASSIS has been investigating how the data could be made more accessible with some relatively minor changes to the observational metadata. The project has been looking at the services that are used within the domain and determining whether they are interoperable with each other and if not what would be required make them so. It has also been examining all types of metadata that are used when identifying and using observations and trying to make them more compliant with techniques and standards developed by bodies such as the International Virtual Observatory Alliance (IVOA). Many of the lessons that are being learnt in the study are applicable to domains that go beyond those directly involved in heliophysics. Adopting some simple standards related to the design of the services interfaces and metadata that are used would make it much easier to investigate interdisciplinary science topics. We will report on our finding and describe a roadmap for the future. For more information about CASSIS, please visit the project Web site on cassis-vo.eu

Changes in glaciers in the Swiss Alps and impact on basin hydrology: current state of the art and future research.

PubMed

Pellicciotti, F; Carenzo, M; Bordoy, R; Stoffel, M

2014-09-15

Switzerland is one of the countries with some of the longest and best glaciological data sets. Its glaciers and their changes in response to climate have been extensively investigated, and the number and quality of related studies are notable. However, a comprehensive review of glacier changes and their impact on the hydrology of glacierised catchments for Switzerland is missing and we use the opportunity provided by the EU-FP7 ACQWA project to review the current state of knowledge about past changes and future projections. We examine the type of models that have been applied to infer glacier evolution and identify knowledge gaps that should be addressed in future research in addition to those indicated in previous publications. Common characteristics in long-term series of projected future glacier runoff are an initial peak followed by a decline, associated with shifts in seasonality, earlier melt onset and reduced summer runoff. However, the quantitative predictions are difficult to compare, as studies differ in terms of model structure, calibration strategies, input data, temporal and spatial resolution as well as future scenarios used for impact studies. We identify two sources of uncertainties among those emerging from recent research, and use simulations over four glaciers to: i) quantify the importance of the correct extrapolation of air temperature, and ii) point at the key role played by debris cover in modulating glacier response. Copyright © 2014 Elsevier B.V. All rights reserved.

Confronting the demand and supply of snow seasonal forecasts for ski resorts : the case of French Alps

NASA Astrophysics Data System (ADS)

Dubois, Ghislain

2017-04-01

Alpine ski resorts are highly dependent on snow, which availability is characterized by a both a high inter-annual variability and a gradual diminution due to climate change. Due to this dependency to climatic resources, the ski industry is increasingly affected by climate change: higher temperatures limit snow falls, increase melting and limit the possibilities of technical snow making. Therefore, since the seventies, managers drastically improved their practices, both to adapt to climate change and to this inter-annual variability of snow conditions. Through slope preparation and maintenance, snow stock management, artificial snow making, a typical resort can approximately keep the same season duration with 30% less snow. The ski industry became an activity of high technicity The EUPORIAS FP7 (www.euporias.eu) project developed between 2012 and 2016 a deep understanding of the supply and demand conditions for the provision of climate services disseminating seasonal forecasts. In particular, we developed a case study, which allowed conducting several activities for a better understanding of the demand and of the business model of future services applied to the ski industry. The investigations conducted in France inventoried the existing tools and databases, assessed the decision making process and data needs of ski operators, and provided evidences that some discernable skill of seasonal forecasts exist. This case study formed the basis of the recently funded PROSNOW H2020 project. We will present the main results of EUPORIAS project for the ski industry.

Estimation of wind regime from combination of RCM and NWP data in the Gulf of Riga (Baltic Sea)

NASA Astrophysics Data System (ADS)

Sile, T.; Sennikovs, J.; Bethers, U.

2012-04-01

Gulf of Riga is a semi-enclosed gulf located in the Eastern part of the Baltic Sea. Reliable wind climate data is crucial for the development of wind energy. The objective of this study is to create high resolution wind parameter datasets for the Gulf of Riga using climate and numerical weather prediction (NWP) models as an alternative to methods that rely on observations with the expectation of benefit from comparing different approaches. The models used for the estimation of the wind regime are an ensemble of Regional Climate Models (RCM, ENSEMBLES, 23 runs are considered) and high resolution NWP data. Future projections provided by RCM are of interest however their spatial resolution is unsatisfactory. We describe a method of spatial refinement of RCM data using NWP data to resolve small scale features. We apply the method of RCM bias correction (Sennikovs and Bethers, 2009) previously used for temperature and precipitation to wind data and use NWP data instead of observations. The refinement function is calculated using contemporary climate (1981- 2010) and later applied to RCM near future (2021 - 2050) projections to produce a dataset with the same resolution as NWP data. This method corrects for RCM biases that were shown to be present in the initial analysis and inter-model statistical analysis was carried out to estimate uncertainty. Using the datasets produced by this method the current and future projections of wind speed and wind energy density are calculated. Acknowledgments: This research is part of the GORWIND (The Gulf of Riga as a Resource for Wind Energy) project (EU34711). The ENSEMBLES data used in this work was funded by the EU FP6 Integrated Project ENSEMBLES (Contract number 505539) whose support is gratefully acknowledged.

EMSO: European Multidisciplinary Seafloor Observatory

NASA Astrophysics Data System (ADS)

Favali, Paolo

2010-05-01

EMSO, a Research Infrastructure listed within ESFRI (European Strategy Forum on Research Infrastructures) Roadmap (Report 2006, http://cordis.europa.eu/esfri/roadmap.htm), is the European-scale network of multidisciplinary seafloor observatories from the Arctic to the Black Sea with the scientific objective of long-term real-time monitoring of processes related to geosphere/biosphere/hydrosphere interactions. EMSO will enhance our understanding of processes through long time series appropriate to the scale of the phenomena, constituting the new frontier of studying Earth interior, deep-sea biology and chemistry and ocean processes. The development of an underwater network is based on previous EU-funded projects since early '90 and is being supported by several EU initiatives, as the on-going ESONET-NoE, coordinated by IFREMER (2007-2011, http://www.esonet-emso.org/esonet-noe/), and aims at gathering together the Research Community of the Ocean Observatories. In 2006 the FP7 Capacities Programme launched a call for Preparatory Phase (PP) projects, that will provide the support to create the legal and organisational entities in charge of managing the infrastructures, and coordinating the financial effort among the countries. Under this call the EMSO-PP project was approved in 2007 with the coordination of INGV and the participation of other 11 Institutions of 11 countries. The project has started in April 2008 and will last 4 years. The EMSO is a key-infrastructure both for Ocean Sciences and for Solid Earth Sciences. In this respect it will enhance and complement profitably the capabilities of other European research infrastructures such as EPOS, ERICON-Aurora Borealis, and SIOS. The perspective of the synergy among EMSO and other ESFRI Research Infrastructures will be outlined. EMSO Partners: IFREMER-Institut Français de Recherche pour l'exploitation de la mer (France, ref. Roland Person); KDM-Konsortium Deutsche Meeresforschung e.V. (Germany, ref. Christoph Waldmann); IMI-Irish Marine Institute (Ireland, ref. Michael Gillooly); UTM-CSIC-Unidad de Tecnologia Marina - Consejo Superior de Investigaciones Cientificas (Spain, ref. Juan Jose Danobeitia); UGOT-Goteborgs Universitet (Sweden, ref. Per Hall); HCMR-Hellenic Centre for Marine Research (Greece, ref. Vasilios Likousis); NOCS-National Oceanography Centre Southampton (United Kingdom, ref. Henry A. Ruhl); UiT-University of Tromsø (Norway, ref. Jürgen Mienert); FCT-Fundação para a Ciência e a Tecnologia (Portugal, ref. Jorge Miguel Alberto de Miranda); ITU-Istanbul Teknik Universitesi (Turkey, ref. Namik Çagatay); NIOZ-Stichting Koninklijk Nederlands Instituut voor Onderzoek der Zee (The Netherlands, ref. Jens Greinert).

Quality Assurance for Essential Climate Variables

NASA Astrophysics Data System (ADS)

Folkert Boersma, K.; Muller, Jan-Peter

2015-04-01

Satellite data are of central interest to the QA4ECV project. Satellites have revolutionized the Earth's observation system of climate change and air quality over the past three decades, providing continuous data for the entire Earth. However, many users of these data are lost in the fog as to the quality of these satellite data. Because of this, the European Union expressed in its 2013 FP7 Space Research Call a need for reliable, traceable, and understandable quality information on satellite data records that could serve as a blueprint contribution to a future Copernicus Climate Change Service. The potential of satellite data to benefit climate change and air quality services is too great to be ignored. QA4ECV therefore bridges the gap between end-users of satellite data and the satellite data products. We are developing an internationally acceptable Quality Assurance (QA) framework that provides understandable and traceable quality information for satellite data used in climate and air quality services. Such a framework should deliver the historically linked long-term data sets that users need, in a format that they can readily use. QA4ECV has approached more than 150 users and suppliers of satellite data to collect their needs and expectations. The project will use their response as a guideline for developing user-friendly tools to obtain information on the completeness, accuracy, and fitness-for-purpose of the satellite datasets. QA4ECV collaborates with 4 joint FP7 Space projects in reaching out to scientists, policy makers, and other end-users of satellite data to improve understanding of the special challenges -and also opportunities- of working with satellite data for climate and air quality purposes. As a demonstration of its capacity, QA4ECV will generate multi-decadal climate data records for 3 atmospheric ECV precursors (nitrogen dioxide, formaldehyde, and carbon monoxide) and 3 land ECVs (albedo, leaf area index and absorbed photosynthetically active radiation), with full uncertainty metrics for every pixel. Multi-use tools and SI/community reference standards will be developed. But QA4ECV is not only about satellites. It is also about exploiting independent reference data obtained from in situ networks, and applying these data with the right, traceable methodologies for quality assurance of the satellite ECVs. The QA4ECV project started in January 2014, as a partnership between 17 research institutes from 7 different European countries working together for a period of 4 years. All QA4ECV partners are closely involved in projects improving, validating, and using satellite data. We hope that QA4ECV will be a major step forward in providing quality assured long-term climate data records that are relevant for policy and climate change assessments. A detailed description of the project can be found at http://qa4ecv.eu.

Frontal Polymerization in Microgravity Summary of Research

NASA Technical Reports Server (NTRS)

Pojman, John A.

2002-01-01

The project began with frontal polymerization (FP). We studied many aspects of FP on the ground and performed two successful weeks of flying on the KC-135. The project evolved into the current flight investigation, Transient Interfacial Phenomena in Miscible Polymer Systems (TIPMPS), as we recognized that an essential question could best be studied using a non-frontal approach. We present detailed results from our ground-based work on FP, KC-135 results and the background, justification and numerical work for the TIPMPS project.

The ASTARTE Paleotsunami Deposits data base - web-based references for tsunami research in the NEAM region

NASA Astrophysics Data System (ADS)

De Martini, P. M.; Pantosti, D.; Orefice, S.; Smedile, A.; Patera, A.; Paris, R.; Terrinha, P.; Hunt, J.; Papadopoulos, G. A.; Noiva, J.; Triantafyllou, I.; Yalciner, A. C.

2017-12-01

EU project ASTARTE aimed at developing a higher level of tsunami hazard assessment in the North-Eastern Atlantic, the Mediterranean and connected seas (NEAM) region by a combination of field work, experimental work, numerical modeling and technical development. The project was a cooperative work of 26 institutes from 16 countries and linked together the description of past tsunamigenic events, the identification and characterization of tsunami sources, the calculation of the impact of such events, and the development of adequate resilience and risks mitigation strategies (http://www.astarte-project.eu/). Within ASTARTE, a web-based database on Paleotsunami Deposits in the NEAM area was created with the purpose to be the future information repository for tsunami research in the broad region. The aim of the project is the integration of every existing official scientific reports and peer reviewed papers on this topic. The database, which archives information and detailed data crucial for tsunami modeling, will be updated on new entries every 12 months. A relational database managed by ArcGIS for Desktop 10.x software has been implemented. One of the final goals of the project is the public sharing of the archived dataset through a web-based map service that will allow visualizing, querying, analyzing, and interpreting the dataset. The interactive map service is hosted by ArcGIS Online and will deploy the cloud capabilities of the portal. Any interested users will be able to access the online GIS resources through any Internet browser or specific apps that run on desktop machines, smartphones, or tablets and will be able to use the analytical tools, key tasks, and workflows of the service. We will present the database structure (characterized by the presence of two main tables: the Site table and the Event table) and topics as well as their ArcGIS Online version. To date, a total of 151 sites and 220 tsunami evidence have been recorded within the ASTARTE database. The ASTARTE Paleotsunami Deposits database - NEAM region is now available online at the address http://arcg.is/1CWz0. The research leading to these results has received funding from the European Union's Seventh Framework Programme (FP7/2007-2013) under grant agreement n° 603839 (Project ASTARTE - Assessment, Strategy and Risk Reduction for Tsunamis in Europe).

A Coastal Risk Assessment Framework Tool to Identify Hotspots at the Regional Scale

NASA Astrophysics Data System (ADS)

Van Dongeren, A.; Viavattene, C.; Jimenez, J. A.; Ferreira, O.; Bolle, A.; Owen, D.; Priest, S.

2016-02-01

Extreme events in combination with an increasing population on the coast, future sea level rise and the deterioration of coastal defences can lead to catastrophic consequences for coastal communities and their activities. The Resilience-Increasing Strategies for Coasts - toolkit (RISC-KIT) FP7 EU project is producing a set of EU-coherent open-source and open-access tools in support of coastal managers and decision-makers. This paper presents one of these tools, the Coastal Risk Assessment Framework (CRAF) which assesses coastal risk at a regional scale to identify potential impact hotspots for more detailed assessment. Applying a suite of complex models at a full and detailed regional scale remains difficult and may not be efficient, therefore a 2-phase approach is adopted. CRAF Phase 1 is a screening process based on a coastal-index approach delimiting several hotspots in alongshore length by assessing the potential exposure for every kilometre along the coast. CRAF Phase 2 uses a suite of more complex modelling process (including X-beach 1D, inundation model, impact assessment and Multi-Criteria Analysis approach) to analyse and compare the risks between the aforementioned identified hotspots. Results of its application are compared on 3 European Case Studies, the Flemish highly protected low-lying coastal plain with important urbanization and harbors, a Portuguese coastal lagoon protected by a multi-inlet barrier system, the highly urbanized Catalonian coast with touristic activities at threat. The flexibility of the tool allows tailoring the comparative analysis to these different contexts and to adapt to the quality of resources and data available. Key lessons will be presented.

Automatic optimisation of gamma dose rate sensor networks: The DETECT Optimisation Tool

NASA Astrophysics Data System (ADS)

Helle, K. B.; Müller, T. O.; Astrup, P.; Dyve, J. E.

2014-05-01

Fast delivery of comprehensive information on the radiological situation is essential for decision-making in nuclear emergencies. Most national radiological agencies in Europe employ gamma dose rate sensor networks to monitor radioactive pollution of the atmosphere. Sensor locations were often chosen using regular grids or according to administrative constraints. Nowadays, however, the choice can be based on more realistic risk assessment, as it is possible to simulate potential radioactive plumes. To support sensor planning, we developed the DETECT Optimisation Tool (DOT) within the scope of the EU FP 7 project DETECT. It evaluates the gamma dose rates that a proposed set of sensors might measure in an emergency and uses this information to optimise the sensor locations. The gamma dose rates are taken from a comprehensive library of simulations of atmospheric radioactive plumes from 64 source locations. These simulations cover the whole European Union, so the DOT allows evaluation and optimisation of sensor networks for all EU countries, as well as evaluation of fencing sensors around possible sources. Users can choose from seven cost functions to evaluate the capability of a given monitoring network for early detection of radioactive plumes or for the creation of dose maps. The DOT is implemented as a stand-alone easy-to-use JAVA-based application with a graphical user interface and an R backend. Users can run evaluations and optimisations, and display, store and download the results. The DOT runs on a server and can be accessed via common web browsers; it can also be installed locally.

The ToxBank Data Warehouse: Supporting the Replacement of In Vivo Repeated Dose Systemic Toxicity Testing.

PubMed

Kohonen, Pekka; Benfenati, Emilio; Bower, David; Ceder, Rebecca; Crump, Michael; Cross, Kevin; Grafström, Roland C; Healy, Lyn; Helma, Christoph; Jeliazkova, Nina; Jeliazkov, Vedrin; Maggioni, Silvia; Miller, Scott; Myatt, Glenn; Rautenberg, Michael; Stacey, Glyn; Willighagen, Egon; Wiseman, Jeff; Hardy, Barry

2013-01-01

The aim of the SEURAT-1 (Safety Evaluation Ultimately Replacing Animal Testing-1) research cluster, comprised of seven EU FP7 Health projects co-financed by Cosmetics Europe, is to generate a proof-of-concept to show how the latest technologies, systems toxicology and toxicogenomics can be combined to deliver a test replacement for repeated dose systemic toxicity testing on animals. The SEURAT-1 strategy is to adopt a mode-of-action framework to describe repeated dose toxicity, combining in vitro and in silico methods to derive predictions of in vivo toxicity responses. ToxBank is the cross-cluster infrastructure project whose activities include the development of a data warehouse to provide a web-accessible shared repository of research data and protocols, a physical compounds repository, reference or "gold compounds" for use across the cluster (available via wiki.toxbank.net), and a reference resource for biomaterials. Core technologies used in the data warehouse include the ISA-Tab universal data exchange format, REpresentational State Transfer (REST) web services, the W3C Resource Description Framework (RDF) and the OpenTox standards. We describe the design of the data warehouse based on cluster requirements, the implementation based on open standards, and finally the underlying concepts and initial results of a data analysis utilizing public data related to the gold compounds. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Experimentally simulating the dynamics of quantum light and matter at ultrastrong coupling using circuit QED (1) - implementation and matter dynamics -

NASA Astrophysics Data System (ADS)

Kounalakis, M.; Langford, N. K.; Sagastizabal, R.; Dickel, C.; Bruno, A.; Luthi, F.; Thoen, D. J.; Endo, A.; Dicarlo, L.

The field dipole coupling of quantum light and matter, described by the quantum Rabi model, leads to exotic phenomena when the coupling strength g becomes comparable or larger than the atom and photon frequencies ωq , r. In this ultra-strong coupling regime, excitations are not conserved, leading to collapse-revival dynamics in atom and photon parity and Schrödinger-cat-like atom-photon entanglement. We realize a quantum simulation of the Rabi model using a transmon qubit coupled to a resonator. In this first part, we describe our analog-digital approach to implement up to 90 symmetric Trotter steps, combining single-qubit gates with the Jaynes-Cummings interaction naturally present in our circuit QED system. Controlling the phase of microwave pulses defines a rotating frame and enables simulation of arbitrary parameter regimes of the Rabi model. We demonstrate measurements of qubit parity dynamics showing revivals at g /ωr > 0 . 8 for ωq = 0 and characteristic dynamics for nondegenerate ωq from g / 4 to g. Funding from the EU FP7 Project ScaleQIT, an ERC Grant, the Dutch Research Organization NWO, and Microsoft Research.

Comparison of multiple atmospheric chemistry schemes in C-IFS

NASA Astrophysics Data System (ADS)

Flemming, Johannes; Huijnen, Vincent; Arteta, Joaquim; Stein, Olaf; Inness, Antje; Josse, Beatrice; Schultz, Martin; Peuch, Vincent-Henri

2013-04-01

As part of the MACCII -project (EU-FP7) ECMWF's integrated forecast system (IFS) is being extended by modules for chemistry, deposition and emission of reactive gases. This integration of the chemistry complements the integration of aerosol processes in IFS (Composition-IFS). C-IFS provides global forecasts and analysis of atmospheric composition. Its main motivation is to utilize the IFS for the assimilation of satellite observation of atmospheric composition. Furthermore, the integration of chemistry packages directly into IFS will achieve better consistency in terms of the treatment of physical processes and has the potential for simulating interactions between atmospheric composition and meteorology. Atmospheric chemistry in C-IFS can be represented by the modified CB05 scheme as implemented in the TM5 model and the RACMOBUS scheme as implemented in the MOCAGE model. An implementation of the scheme of the MOZART 3.5 model is ongoing. We will present the latest progress in the development and application of C-IFS. We will focus on the comparison of the different chemistry schemes in an otherwise identical C-IFS model setup (emissions, meteorology) as well as in their original Chemistry and Transport Model setup.

High sensitivity broadband 360GHz passive receiver for TeraSCREEN

NASA Astrophysics Data System (ADS)

Wang, Hui; Oldfield, Matthew; Maestrojuán, Itziar; Platt, Duncan; Brewster, Nick; Viegas, Colin; Alderman, Byron; Ellison, Brian N.

2016-05-01

TeraSCREEN is an EU FP7 Security project aimed at developing a combined active, with frequency channel centered at 360 GHz, and passive, with frequency channels centered at 94, 220 and 360 GHz, imaging system for border controls in airport and commercial ferry ports. The system will include automatic threat detection and classification and has been designed with a strong focus on the ethical, legal and practical aspects of operating in these environments and with the potential threats in mind. Furthermore, both the passive and active systems are based on array receivers with the active system consisting of a 16 element MIMO FMCW radar centered at 360 GHz with a bandwidth of 30 GHz utilizing a custom made direct digital synthesizer. The 16 element passive receiver system at 360 GHz uses commercial Gunn diode oscillators at 90 GHz followed by custom made 90 to 180 GHz frequency doublers supplying the local oscillator for 360 GHz sub-harmonic mixers. This paper describes the development of the passive antenna module, local oscillator chain, frequency mixers and detectors used in the passive receiver array of this system. The complete passive receiver chain is characterized in this paper.

GALE: a generic open source extensible adaptation engine

NASA Astrophysics Data System (ADS)

De Bra, Paul; Knutov, Evgeny; Smits, David; Stash, Natalia; Ramos, Vinicius F. C.

2013-06-01

This paper motivates and describes GALE, the Generic Adaptation Language and Engine that came out of the GRAPPLE EU FP7 project. The main focus of the paper is the extensible nature of GALE. The purpose of this description is to illustrate how a single core adaptation engine can be used for different types of adaptation, applied to different types of information items and documents. We illustrate the adaptive functionality on some examples of hypermedia documents. In April 2012, David Smits defended the world's first adaptive PhD thesis on this topic. The thesis, available for download and direct adaptive access at http://gale.win.tue.nl/thesis, shows that a single source of information can serve different audiences and at the same time also allows more freedom of navigation than is possible in any paper or static hypermedia document. The same can be done for course texts, hyperfiction, encyclopedia, museum, or other cultural heritage websites, etc. We explain how to add functionality to GALE if desired, to adapt the system's behavior to whatever the application requires. This stresses our main objective: to provide a technological base for adaptive (hypermedia) system researchers on which they can build extensions for the specific research they have in mind.

"Good Vibrations": A workshop on oscillations and normal modes

NASA Astrophysics Data System (ADS)

Barbieri, Sara; Carpineti, Marina; Giliberti, Marco; Rigon, Enrico; Stellato, Marco; Tamborini, Marina

2016-05-01

We describe some theatrical strategies adopted in a two hour workshop in order to show some meaningful experiments and the underlying useful ideas to describe a secondary school path on oscillations, that develops from harmonic motion to normal modes of oscillations, and makes extensive use of video analysis, data logging, slow motions and applet simulations. Theatre is an extremely useful tool to stimulate motivation starting from positive emotions. That is the reason why the theatrical approach to the presentation of physical themes has been explored by the group "Lo spettacolo della Fisica" (http://spettacolo.fisica.unimi.it) of the Physics Department of University of Milano for the last ten years (Carpineti et al., JCOM, 10 (2011) 1; Nuovo Cimento B, 121 (2006) 901) and has been inserted also in the European FP7 Project TEMI (Teaching Enquiry with Mysteries Incorporated, see http://teachingmysteries.eu/en) which involves 13 different partners coming from 11 European countries, among which the Italian (Milan) group. According to the TEMI guidelines, this workshop has a written script based on emotionally engaging activities of presenting mysteries to be solved while participants have been involved in nice experiments following the developed path.

Rapid earthquake hazard and loss assessment for Euro-Mediterranean region

NASA Astrophysics Data System (ADS)

Erdik, Mustafa; Sesetyan, Karin; Demircioglu, Mine; Hancilar, Ufuk; Zulfikar, Can; Cakti, Eser; Kamer, Yaver; Yenidogan, Cem; Tuzun, Cuneyt; Cagnan, Zehra; Harmandar, Ebru

2010-10-01

The almost-real time estimation of ground shaking and losses after a major earthquake in the Euro-Mediterranean region was performed in the framework of the Joint Research Activity 3 (JRA-3) component of the EU FP6 Project entitled "Network of Research Infra-structures for European Seismology, NERIES". This project consists of finding the most likely location of the earthquake source by estimating the fault rupture parameters on the basis of rapid inversion of data from on-line regional broadband stations. It also includes an estimation of the spatial distribution of selected site-specific ground motion parameters at engineering bedrock through region-specific ground motion prediction equations (GMPEs) or physical simulation of ground motion. By using the Earthquake Loss Estimation Routine (ELER) software, the multi-level methodology developed for real time estimation of losses is capable of incorporating regional variability and sources of uncertainty stemming from GMPEs, fault finiteness, site modifications, inventory of physical and social elements subjected to earthquake hazard and the associated vulnerability relationships.

Production of Arctic Sea-ice Albedo by fusion of MISR and MODIS data

NASA Astrophysics Data System (ADS)

Kharbouche, Said; Muller, Jan-Peter

2017-04-01

We have combined data from the NASA MISR and MODIS spectro-radiometers to create a cloud-free albedo dataset specifically for sea-ice. The MISR (Multi-Angular Spectro-Radiometer) instrument on board Terra satellite has a unique ability to create high-quality Bidirectional Reflectance (BRF) over a 7 minute time interval per single overpass, thanks to its 9 cameras of different view angles (±70°,±60°,±45°,±26°). However, as MISR is limited to narrow spectral bands (443nm, 555nm, 670nm, 865nm), which is not sufficient to mask cloud effectively and robustly, we have used the sea-ice mask MOD09 product (Collection 6) from MODIS (Moderate resolution Imaging Spectoradiometer) instrument, which is also on board Terra satellite and acquiring data simultaneously. Only We have created a new and consistent sea-ice (for Arctic) albedo product that is daily, from 1st March to 22nd September for each and every year between 2000 to 2016 at two spatial grids, 1km x 1km and 5km x 5km in polar stereographic projection. Their analysis is described in a separate report [1]. References [1] Muller & Kharbouche, Variation of Arctic's Sea-ice Albedo between 2000 and 2016 by fusion of MISR and MODIS data. This conference. Acknowledgements This work was supported by www.QA4ECV.eu, a project of European Union's Seventh Framework Programme (FP7/2007-2013) under grant agreement no. 607405. We thank our colleagues at JPL and NASA LaRC for processing these data, especially Sebastian Val and Steve Protack.

The Energy-Efficient Quarry: Towards improved understanding and optimisation of energy use and minimisation of CO2 generation in the aggregates industry.

NASA Astrophysics Data System (ADS)

Hill, Ian; White, Toby; Owen, Sarah

2014-05-01

Extraction and processing of rock materials to produce aggregates is carried out at some 20,000 quarries across the EU. All stages of the processing and transport of hard and dense materials inevitably consume high levels of energy and have consequent significant carbon footprints. The FP7 project "the Energy Efficient Quarry" (EE-Quarry) has been addressing this problem and has devised strategies, supported by modelling software, to assist the quarrying industry to assess and optimise its energy use, and to minimise its carbon footprint. Aggregate quarries across Europe vary enormously in the scale of the quarrying operations, the nature of the worked mineral, and the processing to produce a final market product. Nevertheless most quarries involve most or all of a series of essential stages; deposit assessment, drilling and blasting, loading and hauling, and crushing and screening. The process of determining the energy-efficiency of each stage is complex, but is broadly understood in principle and there are numerous sources of information and guidance available in the literature and on-line. More complex still is the interaction between each of these stages. For example, using a little more energy in blasting to increase fragmentation may save much greater energy in later crushing and screening, but also generate more fines material which is discarded as waste and the embedded energy in this material is lost. Thus the calculation of the embedded energy in the waste material becomes an input to the determination of the blasting strategy. Such feedback loops abound in the overall quarry optimisation. The project has involved research and demonstration operations at a number of quarries distributed across Europe carried out by all partners in the EE-Quarry project, working in collaboration with many of the major quarrying companies operating in the EU. The EE-Quarry project is developing a sophisticated modelling tool, the "EE-Quarry Model" available to the quarrying industry on a web-based platform. This tool guides quarry managers and operators through the complex, multi-layered, iterative, process of assessing the energy efficiency of their own quarry operation. They are able to evaluate the optimisation of the energy-efficiency of the overall quarry through examining both the individual stages of processing, and the interactions between them. The project is also developing on-line distance learning modules designed for Continuous Professional Development (CPD) activities for staff across the quarrying industry in the EU and beyond. The presentation will describe development of the model, and the format and scope of the resulting software tool and its user-support available to the quarrying industry.

COOP+ project: Promoting the cooperation among international Research Infrastructures to address global environmental challenges.

NASA Astrophysics Data System (ADS)

Bonet-García, Francisco; Materia, Paola; Kutsch, Werner; de Lucas, Jesús Marco; Tjulin, Anders

2016-04-01

During the Anthropocene, mankind will face several global environmental challenges. One of the first and more successful responses provided by Science to these challenges is the collecting of long-term series of biophysical variables in order to improve our knowledge of natural systems. The huge amount of information gathered during the last decades by Research Infrastructures (RIs) has helped to understand the structure and functioning of natural systems at local and regional scales. But how can we address the global cross-scale and cross-disciplinary challenges posed by the global environment change? We believe that it will be necessary to observe, model better and understand the whole biosphere using long term data generated by international RIs. RIs play a key role on many of the last advances and discoveries in science, from the observation of the Higgs Boson at CERN to the exploration of the Universe by the telescopes of the European Southern Observatory in Chile. The scale of complexity, instrumentation, computing resources, technological advances, and also of the investments, and the size of research collaborations, do not have precedents in Science. RIs in environmental field are developing fast, but the corresponding communities need yet to further reflect the need for a wider global collaboration because the challenges to tackle are in essence of global nature. This contribution describes how COOP+ project (EU Horizon 2020 Coordination and Support Action) will promote the cooperation among RIs at a global scale to address global environmental challenges. Our project evolves from the experience of the sucessful FP7 COOPEUS project (see http://www.coopeus.eu), which explored the use and access to data from RIs in environmental research in Europe and USA. The general goal of COOP+ is to strengthen the links and coordination of the ESFRI RIs related to Marine Science (EMSO), Arctic and Atmospheric Research (EISCAT), Carbon Observation (ICOS) and Biodiversity (LifeWatch) with international counterparts (NEON, TERN, AMISR/SRI, CGSM, OOI, INPA/LBA, IMOS, OCN, AMERIFLUX, etc.) and to leverage international scientific cooperation and data exchange with non-EU countries. During the time span of COOP+ (March 2016 to July 2018), we will address several important questions regarding RIs: What could be the contribution of international RIs to address cross-disciplinary global challenges like modelling and understanding the carbon cycle? Is it feasible to join the knowledge gathered in Arctic research with marine science outputs into comprehensive global models? What collaboration approaches could be implemented to foster the cooperation among RIs? What is the role of local observatories (bottom-up) in this cooperation framework? This contribution will describe COOP+ project using the concept of global challenge. We will describe several possible case study that could be addressed by a network of international RIs.

Successes and challenges of north–south partnerships – key lessons from the African/Asian Regional Capacity Development projects

PubMed Central

Färnman, Rosanna; Diwan, Vishal; Zwarenstein, Merrick; Atkins, Salla

2016-01-01

Introduction Increasing efforts are being made globally on capacity building. North–south research partnerships have contributed significantly to enhancing the research capacity in low- and middle-income countries (LMICs) over the past few decades; however, a lack of skilled researchers to inform health policy development persists, particularly in LMICs. The EU FP7 funded African/Asian Regional Capacity Development (ARCADE) projects were multi-partner consortia aimed to develop a new generation of highly trained researchers from universities across the globe, focusing on global health-related subjects: health systems and services research and research on social determinants of health. This article aims to outline the successes, challenges and lessons learned from the life course of the projects, focusing on the key outputs and experiences of developing and implementing these two projects together with sub-Saharan African, Asian and European institution partners. Design Sixteen participants from 12 partner institutions were interviewed. The data were analysed using thematic content analysis, which resulted in four themes and three sub-categories. These data were complemented by a review of project reports. Results The results indicated that the ARCADE projects have been successful in developing and delivering courses, and have reached over 920 postgraduate students. Some partners thought the north–south and south–south partnerships that evolved during the project were the main achievement. However, others found there to be a ‘north–south divide’ in certain aspects. Challenges included technical constraints and quality assurance. Additionally, adapting new teaching and learning methods into current university systems was challenging, combined with not being able to award students with credits for their degrees. Conclusion The ARCADE projects were introduced as an innovative and ambitious project idea, although not designed appropriately for all partner institutions. Some challenges were underestimated from the beginning, and for such future projects, a more structured approach needs to be adopted. ARCADE partners learned that integrating courses into current university systems and awarding students credits are essential. PMID:27725080

Successes and challenges of north-south partnerships - key lessons from the African/Asian Regional Capacity Development projects.

PubMed

Färnman, Rosanna; Diwan, Vishal; Zwarenstein, Merrick; Atkins, Salla

2016-01-01

Increasing efforts are being made globally on capacity building. North-south research partnerships have contributed significantly to enhancing the research capacity in low- and middle-income countries (LMICs) over the past few decades; however, a lack of skilled researchers to inform health policy development persists, particularly in LMICs. The EU FP7 funded African/Asian Regional Capacity Development (ARCADE) projects were multi-partner consortia aimed to develop a new generation of highly trained researchers from universities across the globe, focusing on global health-related subjects: health systems and services research and research on social determinants of health. This article aims to outline the successes, challenges and lessons learned from the life course of the projects, focusing on the key outputs and experiences of developing and implementing these two projects together with sub-Saharan African, Asian and European institution partners. Sixteen participants from 12 partner institutions were interviewed. The data were analysed using thematic content analysis, which resulted in four themes and three sub-categories. These data were complemented by a review of project reports. The results indicated that the ARCADE projects have been successful in developing and delivering courses, and have reached over 920 postgraduate students. Some partners thought the north-south and south-south partnerships that evolved during the project were the main achievement. However, others found there to be a 'north-south divide' in certain aspects. Challenges included technical constraints and quality assurance. Additionally, adapting new teaching and learning methods into current university systems was challenging, combined with not being able to award students with credits for their degrees. The ARCADE projects were introduced as an innovative and ambitious project idea, although not designed appropriately for all partner institutions. Some challenges were underestimated from the beginning, and for such future projects, a more structured approach needs to be adopted. ARCADE partners learned that integrating courses into current university systems and awarding students credits are essential.

Modelling soil carbon flows and stocks following a carbon balance approach at regional scale for the EU-27

NASA Astrophysics Data System (ADS)

Lesschen, Jan Peter; Sikirica, Natasa; Bonten, Luc; Dibari, Camilla; Sanchez, Berta; Kuikman, Peter

2014-05-01

Soil Organic Carbon (SOC) is a key parameter to many soil functions and services. SOC is essential to support water retention and nutrient buffering and mineralization in the soil as well as to enhance soil biodiversity. Consequently, loss of SOC or low SOC levels might threaten soil productivity or even lead to a collapse of a farming system. Identification of areas in Europe with critically low SOC levels or with a negative carbon balance is a challenge in order to apply the appropriate strategies to restore these areas or prevent further SOC losses. The objective of this study is to assess current soil carbon flows and stocks at a regional scale; we follow a carbon balance approach which we developed within the MITERRA-Europe model. MITERRA-Europe is an environmental impact assessment model and calculates nitrogen and greenhouse emission on a deterministic and annual basis using emission and leaching factors at regional level (NUTS2, comparable to province level) in the EU27. The model already contained a soil carbon module based on the IPCC stock change approach. Within the EU FP7 SmartSoil project we developed a SOC balance approach, for which we quantified the input of carbon (manure, crop residues, other organic inputs) and the losses of carbon (decomposition, leaching and erosion). The calculations rules from the Roth-C model were used to estimate SOC decomposition. For the actual soil carbon stocks we used the data from the LUCAS soil sample survey. LUCAS collected soil samples in 2009 at about 22000 locations across the EU, which were analysed for a range of soil properties. Land management practices are accounted for, based on data from the EU wide Survey on Agricultural Production Methods in the 2010 Farm Structure Survey. The survey comprises data on the application of soil tillage, soil cover, crop rotation and irrigation. Based on the simulated soil carbon balance and the actual carbon stocks from LUCAS we now can identify regions within the EU that are at risk. We further present results of the potential soil carbon sequestration by land management practices, such as cover crops, zero and reduced tillage, crop residue management and additional input of organic carbon. These results will be relevant for defining region specific strategies to reach the policy target on preventing loss of soil organic matter as stipulated in the Roadmap to a Resource Efficient Europe.

The Center for Alternatives to Animal Testing - Europe (CAAT-EU): a transatlantic bridge for the paradigm shift in toxicology.

PubMed

Daneshian, Mardas; Leist, Marcel; Hartung, Thomas

2010-01-01

The Center for Alternatives to Animal Testing - Europe (CAAT-EU) was founded based collaboration between the Johns Hopkins Bloomberg School of Public Health and the University of Konstanz. CAAT-EU, housed at the University of Konstanz, will coordinate transatlantic activities to promote humane science in research and education, and participate, as partner or coordinator, in publicly and privately funded European projects. Thomas Hartung will serve as program liaison representing Johns Hopkins University and Marcel Leist as the University of Konstanz liaison. CAAT-EU aims to: 1) Set up transatlantic consortia for international research projects on alternative methods. 2) Establish a CAAT Europe faculty and advisory board composed of sponsor representatives and prominent academics from Europe . 3) Participate in the Transatlantic Think Tank for Toxicology (t4) devoted to conceptual work for the paradigm shift in toxicology. 4) Coordinate a series of information days in Europe on relevant developments in the US, similar to the 2009 series CAAT held in the US on EU issues (one on the 7th Amendment to the EU Cosmetics Directive and one on EU and US chemical regulation). 5) Support ALTEX as the official journal of CAAT and CAAT-EU. 6) Develop strategic projects with sponsors to promote humane science and new toxicology, especially with CAAT faculty members. 7) Develop a joint education program between Johns Hopkins and the University of Konstanz, such as e-courses and the existing Humane Science Certificate program developed by CAAT, a student exchange program, and collaboration with the International Graduate School "Cell-based Characterization of De- and Regeneration" in Konstanz.

Changing pattern of landslide risk in Europe - The SafeLand project

NASA Astrophysics Data System (ADS)

Nadim, F.; Kalsnes, B.

2012-04-01

The need to protect people and property with a changing pattern of landslide hazard and risk caused by climate change and changes in demography, and the reality for societies in Europe to live with the risk associated with natural hazards, were the motives for the project SafeLand: "Living with landslide risk in Europe: Assessment, effects of global change, and risk management strategies." SafeLand is a large, integrating research project under the European Commission's 7th Framework Programme (FP7). The project started on 1 May 2009 and will end on 30 April 2012. It involves 27 partners from 12 European countries, and has international collaborators and advisers from China, India, USA, Japan and Hong Kong. SafeLand also involves 25 End-Users from 11 countries. SafeLand is coordinated by the International Centre for Geohazards (ICG) at Norwegian Geotechnical Institute in Norway. Further information on the SafeLand project can be found at its web site http://safeland-fp7.eu/. Main results achieved in SafeLand include: - Various guidelines related to landslide triggering processes and run-out modelling. - Development and testing of several empirical methods for predicting the characteristics of threshold rainfall events for triggering of precipitation-induced landslides, and development of an empirical model for assessing the changes in landslide frequency (hazard) as a function of changes in the demography and population density. - Guideline for landslide susceptibility, hazard and risk assessment and zoning. - New methodologies for physical and societal vulnerability assessment. - Identification of landslide hazard and risk hotspots for Europe. The results show clearly where areas with the largest landslide risk are located in Europe and the objective approach allows a ranking of the countries by exposed area and population. - Different regional and local climate model simulations over selected regions of Europe at spatial resolutions of 10x10 km and 2.8x2.8 km. These simulations were used to perform an extreme value analysis for trends in heavy precipitation events, and subsequent effects on landslide hazard and risk trends. - Guidelines for use of remote sensing techniques, monitoring and early warning systems. - Development of a prototype web-based "toolbox" of innovative and technically appropriate prevention and mitigation measures. The toolbox does a preliminary assessment and ranking of up to 60 structural and non-structural landslide risk mitigation options. - Case histories and "hotspots" of European Land¬slides have been collected and documented. Data for close to fifty potential case study sites have been compiled and summarized. Most of the case study sites are located in Europe (Italy, France, Norway, Switzerland, Austria, Andorra, and Romania); but they also include one site in Canada and one in India. Almost every type of landslide and every type of movement is represented in these sites. - Research on stakeholder workshops and participatory processes to involve the population exposed to landslide risk in the decision-making process for choosing the most appropriate risk mitigation measure(s).

Towards Cross-Organizational Innovative Business Process Interoperability Services

NASA Astrophysics Data System (ADS)

Karacan, Ömer; Del Grosso, Enrico; Carrez, Cyril; Taglino, Francesco

This paper presents the vision and initial results of the COIN (FP7-IST-216256) European project for the development of open source Collaborative Business Process Interoperability (CBPip) in cross-organisational business collaboration environments following the Software-as-a-Service Utility (SaaS-U) paradigm.

EMSO: European Multidisciplinary Seafloor Observatory

NASA Astrophysics Data System (ADS)

Favali, P.; Partnership, Emso

2009-04-01

EMSO, a Research Infrastructure listed within ESFRI (European Strategy Forum on Research Infrastructures) Roadmap), is the European-scale network of multidisciplinary seafloor observatories from the Arctic to the Black Sea with the scientific objective of long-term real-time monitoring of processes related to geosphere/biosphere/hydrosphere interactions. EMSO will enhance our understanding of processes through long time series appropriate to the scale of the phenomena, constituting the new frontier of studying Earth interior, deep-sea biology and chemistry and ocean processes. EMSO will reply also to the need expressed in the frame of GMES (Global Monitoring for Environment and Security) to develop a marine segment integrated in the in situ and satellite global monitoring system. The EMSO development relays upon the synergy between the scientific community and the industry to improve the European competitiveness with respect to countries like USA/Canada, NEPTUNE, VENUS and MARS projects, Taiwan, MACHO project, and Japan, DONET project. In Europe the development of an underwater network is based on previous EU-funded projects since early '90, and presently supported by EU initiatives. The EMSO infrastructure will constitute the extension to the sea of the land-based networks. Examples of data recorded by seafloor observatories will be presented. EMSO is presently at the stage of Preparatory Phase (PP), funded in the EC FP7 Capacities Programme. The project has started in April 2008 and will last 4 years with the participation of 12 Institutions representing 12 countries. EMSO potential will be significantly increased also with the interaction with other Research Infrastructures addressed to Earth Science. 2. IFREMER-Institut Français de Recherche pour l'exploitation de la mer (France, ref. Roland Person); KDM-Konsortium Deutsche Meeresforschung e.V. (Germany, ref. Christoph Waldmann); IMI-Irish Marine Institute (Ireland, ref. Michael Gillooly); UTM-CSIC-Unidad de Tecnologia Marina - Consejo Superior de Investigaciones Cientificas (Spain, ref. Juan Jose Danobeitia); UGOT-Goteborgs Universitet (Sweden, ref. Per Hall); HCMR-Hellenic Centre for Marine Research (Greece, ref. Vasilios Likousis); NOCS-National Oceanography Centre Southampton (United Kingdom, ref. Henry A. Ruhl); UiT-University of Tromsø (Norway, ref. Jürgen Mienert); FCT-Fundação para a Ciência e a Tecnologia (Portugal, ref. Jorge Miguel Alberto de Miranda); ITU-Istanbul Teknik Universitesi (Turkey, ref. Namik Çagatay); NIOZ-Stichting Koninklijk Nederlands Instituut voor Zeeonderzoek (The Netherlands, ref. Tjeerd C.E. van Weering).

EU-FP7-iMars: Analysis of Mars Multi-Resolution Images using Auto-Coregistration, Data Mining and Crowd Source Techniques

NASA Astrophysics Data System (ADS)

Ivanov, Anton; Oberst, Jürgen; Yershov, Vladimir; Muller, Jan-Peter; Kim, Jung-Rack; Gwinner, Klaus; Van Gasselt, Stephan; Morley, Jeremy; Houghton, Robert; Bamford, Steven; Sidiropoulos, Panagiotis

Understanding the role of different planetary surface formation processes within our Solar System is one of the fundamental goals of planetary science research. There has been a revolution in planetary surface observations over the last 15 years, especially in 3D imaging of surface shape. This has led to the ability to be able to overlay different epochs back to the mid-1970s, examine time-varying changes (such as the recent discovery of boulder movement, tracking inter-year seasonal changes and looking for occurrences of fresh craters. Consequently we are seeing a dramatic improvement in our understanding of surface formation processes. Since January 2004, the ESA Mars Express has been acquiring global data, especially HRSC stereo (12.5-25 m nadir images) with 87% coverage with more than 65% useful for stereo mapping. NASA began imaging the surface of Mars, initially from flybys in the 1960s and then from the first orbiter with image resolution less than 100 m in the late 1970s from Viking Orbiter. The most recent orbiter, NASA MRO, has acquired surface imagery of around 1% of the Martian surface from HiRISE (at ≈20 cm) and ≈5% from CTX (≈6 m) in stereo. Within the iMars project (http://i-Mars.eu), a fully automated large-scale processing (“Big Data”) solution is being developed to generate the best possible multi-resolution DTM of Mars. In addition, HRSC OrthoRectified Images (ORI) will be used as a georeference basis so that all higher resolution ORIs will be co-registered to the HRSC DTMs (50-100m grid) products generated at DLR and, from CTX (6-20 m grid) and HiRISE (1-3 m grids) on a large-scale Linux cluster based at MSSL. The HRSC products will be employed to provide a geographic reference for all current, future and historical NASA products using automated co-registration based on feature points and initial results will be shown here. In 2015, many of the entire NASA and ESA orbital images will be co-registered and the updated georeferencing information employed to generate a time series of terrain relief with corrected ORIs back to 1977. Web-GIS using OGC protocols will be employed to allow visual exploration of changes to the surface. Data mining processing chains are being developed to search for changes in the Martian surface from 1971-2015 and the output of this data mining will be compared against the results from citizen scientists’ measurements in a specialized Zooniverse implementation. The final co-registered data sets will be distributed through both European and US channels in a manner to be decided towards the end of the project. Acknowledgements: The research leading to these results has received funding from the European Union’s Seventh Framework Programme (FP7/2007-2013) under iMars grant agreement no. 607379.

My school voyages with PERSEUS - PERSEUS@SCHOOL

NASA Astrophysics Data System (ADS)

Fermeli, Georgia; Papathanassiou, Evangelos; Papatheodorou, George; Streftaris, Nikos; Ioakeimidis, Christos

2014-05-01

PERSEUS@SCHOOL is an international environmental education thematic school network which is inspired and supported by the European research project PERSEUS (Policy Oriented Marine Environmental Research in Southern European Seas_http://www.perseus-net.eu) which is funded by EU FP7 Theme "Ocean of Tomorrow" and it is coordinating by the Hellenic Centre for Marine Research (HCMR). The overall scientific objectives of PERSEUS (FP7) research project are to identify the interacting patterns of natural and human-derived pressures on the Mediterranean and Black Seas, assess their impact on marine ecosystems and, using the objectives and principles of the Marine Strategy Framework Directive as a vehicle, to design an effective and innovative research governance framework based on solid scientific knowledge. This research governance framework will engage scientists, policy-makers and the public, thereby reaching a shared understanding and informed decision-making based on sound scientific knowledge. PERSEUS@SCHOOL network is coordinated by the Department of Environmental Education of the 1st Directorate of Secondary Education of Athens and aims to help and enhance environmental education, focusing on clean seas stewardship in schools. Educators along with marine scientists have a role in supporting and inspiring children to acquire the knowledge, skills and inspire their awareness to live and work as responsible and concerned citizens. For this purpose, the network has designed specific pedagogical activities for primary and secondary education - based on PERSEUS key thematic areas i.e. Marine biodiversity, Overfishing, Chemical Marine Pollution - Bioaccumulation - Health, Eutrophication in Marine Waters and Marine Litter. Complementary, two web-monitoring tools will be used by the network; the Jellyfish Spotting campaign and the Marine LitterWatch (MLW) app (Developed by EEA). A special emphasis is given to MLW app, as school students for first time will use it in order to test this new tool and to monitor beach marine litter in selected areas in Greece. The pedagogical activities of the network will give students an opportunity to explore similarities and differences between schools and nationalities, while simultaneously creating awareness of other young people's reality in a captivating way. PERSEUS@SCHOOL will allow students to use their imagination and knowledge provided by PERSEUS scientists, in order to think and act about the marine environment and its protection in an interactive, appealing and imaginative way. Finally, students will participate in a "true" expedition in the Aegean Sea, on the R/V AEGAEO of the Hellenic Centre for Marine Research (HCMR). The aim of this expedition is to involve students in marine scientific research and guide them to recognize the 'value' of the Mediterranean Sea and the threats and challenges it faces in the modern world. During this expedition, students will collaborate with marine scientists creating a powerful interactive learning experience, participate in experiments, interpret research findings, draw conclusions and voice their opinion for the "Oceans of tomorrow".

Exploiting Open Environmental Data using Linked Data and Cloud Computing: the MELODIES project

NASA Astrophysics Data System (ADS)

Blower, Jon; Gonçalves, Pedro; Caumont, Hervé; Koubarakis, Manolis; Perkins, Bethan

2015-04-01

The European Open Data Strategy establishes important new principles that ensure that European public sector data will be released at no cost (or marginal cost), in machine-readable, commonly-understood formats, and with liberal licences enabling wide reuse. These data encompass both scientific data about the environment (from Earth Observation and other fields) and other public sector information, including diverse topics such as demographics, health and crime. Many open geospatial datasets (e.g. land use) are already available through the INSPIRE directive and made available through infrastructures such as the Global Earth Observation System of Systems (GEOSS). The intention of the Open Data Strategy is to stimulate the growth of research and value-adding services that build upon these data streams; however, the potential value inherent in open data, and the benefits that can be gained by combining previously-disparate sources of information are only just starting to become understood. The MELODIES project (Maximising the Exploitation of Linked Open Data In Enterprise and Science) is developing eight innovative and sustainable services, based upon Open Data, for users in research, government, industry and the general public in a broad range of societal and environmental benefit areas. MELODIES (http://melodiesproject.eu) is a European FP7 project that is coordinated by the University of Reading and has sixteen partners (including nine SMEs) from eight European countries. It started in November 2013 and will run for three years. The project is therefore in its early stages and therefore we will value the opportunity that this workshop affords to present our plans and interact with the wider Linked Geospatial Data community. The project is developing eight new services[1] covering a range of domains including agriculture, urban ecosystems, land use management, marine information, desertification, crisis management and hydrology. These services will combine Earth Observation data with other open data sources to produce new information for the benefit of scientists, industry, government decision-makers, public service providers and citizens. The long-term sustainability of the services will be assessed critically throughout the project from a number of angles (technical, political and economic), in order to ensure that the full benefits of the MELODIES project are realised in the long term. The priority of the project, therefore, is to demonstrate that releasing data openly leads to concrete commercial and scientific benefits, and can stimulate the production of new applications and viable services. [1] http://www.melodiesproject.eu/services.html

EU-FP7-iMARS: analysis of Mars multi-resolution images using auto-coregistration, data mining and crowd source techniques: A Final Report on the very variable surface of Mars

NASA Astrophysics Data System (ADS)

Muller, Jan-Peter; Sidiropoulos, Panagiotis; Tao, Yu; Putri, Kiky; Campbell, Jacqueline; Xiong, Si-Ting; Gwinner, Klaus; Willner, Konrad; Fanara, Lida; Waehlisch, Marita; Walter, Sebastian; Schreiner, Bjoern; Steikert, Ralf; Ivanov, Anton; Cantini, Federico; Wardlaw, Jessica; Sprinks, James; Houghton, Robert; Kim, Jung-Rack

2017-04-01

There has been a revolution in 3D surface imaging of Mars over the last 12 years with systematic stereoscopy from HRSC. Digital Terrain Models (DTMs) and OrthoRectified Images (ORIs) have been produced for almost 50% of the Martian surface. DLR, together with the HRSC science team, produced 3D HRSC mosaic products for large regions comprising around 100 individual strips per region (MC-11E/W). UCL processed full coverage of DTMs over the South Polar Residual Cap (SPRC) and started work on the North Polar Layered Deposits (NPLD). The iMars project has been exploiting this unique set of 3D products as a basemap to co-register NASA imagery going back to the 1970s. UCL have developed an automated processing chain for CTX and HiRISE 3D processing to densify the global HRSC dataset with DTMs down to 18m and 75cm respectively using a modification of the open source NASA Ames Stereo Pipeline [1]. 1542 CTX DTMs + ORIs were processed using the Microsoft Azure® cloud and an in-house linux cluster. It is planned to process around 10% of the total HiRISE stereo-DTMs before the end of the project. A fully Automated Co-Registration and Orthorectification (ACRO) system has been developed at UCL and applied to the production of around some 15,000 NASA images. These were co-registered co-registered to a HRSC pixel (typically 12.5m/pixel) and orthorectified to HRSC DTMs of 50-150m spacing [2] over MC-11E/W. All of these new products images are viewable through an OGC-compliant webGIS developed at FUB,. This includes tools for viewing temporal sequences of co-registered ORIs over the same area [3]. Corresponding MARSIS and SHARAD data can be viewed through a QGIS plugin made publicly available [4]. An automated data mining system has been developed at UCL [5] for change detection to search and classify features in images going back to Viking Orbiter of IFoV ≤100m. In parallel, a citizen science project at Nottingham University [6] has defined training samples for classification of change features and eventually for verification of change [7]. Scientific applications include change mapping over MC11E/W, the SPRC [8], mass movements near the North Pole [9]; dark streaks [10] CRISM mapping of mineralogy of dust in the SPRC "Swiss cheese" layers [11] and mapping of dune movement [12]. Examples of some of these will be shown. [1] Tao, Y. & J.-P. Muller LPSC16-2074; [2] Gwinner, K. et al. EPSC15-672; [3] Walter, S. et al. LPSC17-508; [4] Ivanov, A. & Cantini, F. EPSC16; [5] Sidiropoulos, P. & J.-P. Muller EPSC16; [6] Sprinks et al. EPSC16; [7] Wardlaw et al. EPSC16; [8] Putri et al., EPSC16;[9] Fanara, L. et al. LPSC16-2710; [10] Schreiner, B. et al., EPSC16; [11] Campbell, J.et al., EPSC16;[12] Kim, J-R., et al., EPSC16; Acknowledgements This research has received funding from the EU's FP7 Programme under iMars 607379. Partial support is also provided from the STFC Grant ST/K000977/1. iMars thanks the HRSC Experiment team at DLR, Institute of Planetary Research, Berlin, and at Freie Universität Berlin, the HRSC Science Team, as well as the Mars Express Project teams at ESTEC, ESOC, and ESAC for their successful planning, acquisition, and release of image data to the community.

The Fogo's Collapse-triggered Megatsunami: Evidence-calibrated Numerical Simulations of Tsunamigenic Potential and Coastal Impact

NASA Astrophysics Data System (ADS)

Omira, Rachid; Ramalho, Ricardo S.; Quartau, Rui; Ramalho, Inês; Madeira, José; Baptista, Maria Ana

2017-04-01

Volcanic Ocean Islands are very prominent and dynamic features involving several constructive and destructive phases during their life-cycles. Large-scale gravitational flank collapses are one of the most destructive processes and can present a major source of hazard, since it has been shown that these events are capable of triggering megatsunamis with significant coastal impact. The Fogo volcanic island, Cape Verde, presents evidence for giant edifice mass-wasting, as attested by both onshore and offshore evidence. A recent study by Ramalho et al. (2015) revealed the presence of tsunamigenic deposits that attest the generation of a megatsunami with devastating impact on the nearby Santiago Island, following Fogo's catastrophic collapse. Evidence from northern Santiago implies local minimum run-ups of 270 m, providing a unique physical framework to test collapse-triggered tsunami numerical simulations. In this study, we investigate the tsunamigenic potential associated with Fogo's flank collapse, and its impact on the Islands of the Cape Verde archipelago using field evidence-calibrated numerical simulations. We first reconstruct the pre-event island morphology, and then employ a multilayer numerical model to simulate the flank failure flow towards and under the sea, the ensuing tsunami generation, propagation and coastal impact. We use a digital elevation model that considers the coastline configuration and the sea level at the time of the event. Preliminary numerical modeling results suggest that collapsed volumes of 90-150 km3, in one single event, generate numerical solutions that are compatible with field evidence. Our simulations suggest that Fogo's collapse triggered a megatsunami that reached the coast of Santiago in 8 min, and with wave heights in excess of 250 m. The tsunami waves propagated with lower amplitudes towards the Cape Verde Islands located northward of Fogo. This study will contribute to more realistically assess the scale of risks associated with these extremely rare but very high impact natural disasters. This work is supported by the EU project ASTARTE -Grant 603839, 7th FP (ENV.2013, 6.4-3), the EU project TSUMAPS-NEAM -Agreement Number: ECHO/SUB/2015/718568/PREV26, and the IF/01641/2015 MEGAWAVE - FCT project.

Quantity of flowback and produced waters from unconventional oil and gas exploration.

PubMed

Kondash, Andrew J; Albright, Elizabeth; Vengosh, Avner

2017-01-01

The management and disposal of flowback and produced waters (FP water) is one of the greatest challenges associated with unconventional oil and gas development. The development and production of unconventional natural gas and oil is projected to increase in the coming years, and a better understanding of the volume and quality of FP water is crucial for the safe management of the associated wastewater. We analyzed production data using multiple statistical methods to estimate the total FP water generated per well from six of the major unconventional oil and gas formations in the United States. The estimated median volume ranges from 1.7 to 14.3millionL (0.5 to 3.8milliongal) of FP per well over the first 5-10years of production. Using temporal volume production and water quality data, we show a rapid increase of the salinity associated with a decrease of FP production rates during the first months of unconventional oil and gas production. Based on mass-balance calculations, we estimate that only 4-8% of FP water is composed of returned hydraulic fracturing fluids, while the remaining 92-96% of FP water is derived from naturally occurring formation brines that is extracted together with oil and gas. The salinity and chemical composition of the formation brines are therefore the main limiting factors for beneficial reuse of unconventional oil and gas wastewater. Copyright © 2016 Elsevier B.V. All rights reserved.

[ECRIN (European clinical research infrastructures network), a pan-European infrastructure for clinical research].

PubMed

Demotes-Mainard, Jacques

2010-12-01

Clinical research plays a key role both in the development of innovative health products and in the optimisation of medical strategies, leading to evidence-based practice and healthcare cost containment. ECRIN is a distributed ESFRI-roadmap pan-European infrastructure designed to support multinational clinical research, making Europe a single area for clinical studies, taking advantage of its population size to access patients, and unlocking latent scientific providing services to multinational. Servicing of multinational trials started during the preparatory phase, and ECRIN has applied for ERIC status in 2011. In parallel, ECRIN has also proposed an FP7 integrating activity project to further develop, upgrade and expand the ECRIN infrastructure built up during the past FP6 and FP7 projects, facilitating an efficient organization of clinical research in Europe, with ECRIN developing generic tools and providing generic services for multinational studies, and supporting the construction of pan-European disease-oriented networks that will in turn act as ECRIN users. This organization will improve Europe's attractiveness for industry trials, boost its scientific competitiveness, and result in better healthcare for European citizens. The three medical areas supported in this project (rare diseases, medical devices, and nutrition) will serve as pilots for other biomedical research fields. By creating a single area for clinical research in Europe, this structure will contribute to the implementation of the Europe flagship initiative 2020 'Innovation Union', whose objectives include defragmentation of research and educational capacities, tackling the major societal challenges (starting with healthy aging), and removing barriers to bringing ideas to the market.

Healthcare for migrants, participatory health research and implementation science--better health policy and practice through inclusion. The RESTORE project.

PubMed

MacFarlane, Anne; O'Reilly-de Brún, Mary; de Brún, Tomas; Dowrick, Christopher; O'Donnell, Catherine; Mair, Frances; Spiegel, Wolfgang; van den Muijsenbergh, Maria; van Weel Baumgarten, Evelyn; Lionis, Christos; Clissmann, Ciaran

2014-06-01

This is a time of unprecedented mobility across the globe. Healthcare systems need to adapt to ensure that primary care is culturally and linguistically appropriate for migrants. Evidence-based guidelines and training interventions for cultural competence and the use of professional interpreters are available across European healthcare settings. However, in real-world practice migrants and their healthcare providers 'get by' with a range of informal and inadequate strategies. RESTORE is an EU FP7 funded project, which is designed to address this translational gap. The objective of RESTORE is to investigate and support the implementation of guidelines and training initiatives to support communication in cross-cultural consultations in selected European primary care settings. RESTORE is a qualitative, participatory health project running from 2011-2015. It uses a novel combination of normalization process theory and participatory learning and action research to follow and shape the implementation journeys of relevant guidelines and training initiatives. Research teams in Ireland, England, the Netherlands, Austria and Greece are conducting similar parallel qualitative case study fieldwork, with a complementary health policy analysis led by Scotland. In each setting, key stakeholders, including migrants, are involved in participatory data generation and analysis. RESTORE will provide knowledge about the levers and barriers to the implementation of guidelines and training initiatives in European healthcare settings and about successful, transferrable strategies to overcome identified barriers. RESTORE will elucidate the role of policy in shaping these implementation journeys; generate recommendations for European policy driving the development of culturally and linguistically appropriate healthcare systems.

Overview of the HELCATS project

NASA Astrophysics Data System (ADS)

Harrison, Richard; Davies, Jackie; Perry, Chris; Moestl, Christian; Rouillard, Alexis; Bothmer, Volker; Rodriguez, Luciano; Eastwood, Jonathan; Kilpua, Emilia; Gallagher, Peter; Odstrcil, Dusan

2017-04-01

Understanding solar wind evolution is fundamental to advancing our knowledge of energy and mass transport in the solar system, whilst also being crucial to space weather and its prediction. The advent of truly wide-angle heliospheric imaging has revolutionised the study of solar wind evolution, by enabling direct and continuous observation of both transient and background components of the solar wind as they propagate from the Sun to 1 AU and beyond. The EU-funded FP7 Heliospheric Cataloguing, Analysis and Techniques Service (HELCATS) project combines European expertise in heliospheric imaging, built up over the last decade in particular through lead involvement in NASA's STEREO mission, with expertise in solar and coronal imaging as well as the interpretation of in-situ and radio diagnostic measurements of solar wind phenomena. HELCATS involves: (1) cataloguing of transient (coronal mass ejections) and background (stream/corotating interaction regions) solar wind structures observed by the STEREO/Heliospheric Imagers, including estimates of their kinematic properties based on a variety of modelling techniques; (2) verifying these kinematic properties through comparison with solar source observations and in-situ measurements at multiple points throughout the heliosphere; (3) assessing the potential for initialising numerical models based on the derived kinematic properties of transient and background solar wind components; (4) assessing the complementarity of radio observations (Type II radio bursts and interplanetary scintillation) in the detection and analysis of heliospheric structure in combination with heliospheric imaging observations. We provide an overview of the achievements of the HELCATS project, as it reaches its conclusion, and present selected results that seek to illustrate the value and legacy of this unprecedented, coordinated study of structures in the heliosphere.

Managing the effects of multiple stressors on aquatic ecosystems under water scarcity. The GLOBAQUA project.

PubMed

Navarro-Ortega, Alícia; Acuña, Vicenç; Bellin, Alberto; Burek, Peter; Cassiani, Giorgio; Choukr-Allah, Redouane; Dolédec, Sylvain; Elosegi, Arturo; Ferrari, Federico; Ginebreda, Antoni; Grathwohl, Peter; Jones, Colin; Rault, Philippe Ker; Kok, Kasper; Koundouri, Phoebe; Ludwig, Ralf Peter; Merz, Ralf; Milacic, Radmila; Muñoz, Isabel; Nikulin, Grigory; Paniconi, Claudio; Paunović, Momir; Petrovic, Mira; Sabater, Laia; Sabaterb, Sergi; Skoulikidis, Nikolaos Th; Slob, Adriaan; Teutsch, Georg; Voulvoulis, Nikolaos; Barceló, Damià

2015-01-15

Water scarcity is a serious environmental problem in many European regions, and will likely increase in the near future as a consequence of increased abstraction and climate change. Water scarcity exacerbates the effects of multiple stressors, and thus results in decreased water quality. It impacts river ecosystems, threatens the services they provide, and it will force managers and policy-makers to change their current practices. The EU-FP7 project GLOBAQUA aims at identifying the prevalence, interaction and linkages between stressors, and to assess their effects on the chemical and ecological status of freshwater ecosystems in order to improve water management practice and policies. GLOBAQUA assembles a multidisciplinary team of 21 European plus 2 non-European scientific institutions, as well as water authorities and river basin managers. The project includes experts in hydrology, chemistry, biology, geomorphology, modelling, socio-economics, governance science, knowledge brokerage, and policy advocacy. GLOBAQUA studies six river basins (Ebro, Adige, Sava, Evrotas, Anglian and Souss Massa) affected by water scarcity, and aims to answer the following questions: how does water scarcity interact with other existing stressors in the study river basins? How will these interactions change according to the different scenarios of future global change? Which will be the foreseeable consequences for river ecosystems? How will these in turn affect the services the ecosystems provide? How should management and policies be adapted to minimise the ecological, economic and societal consequences? These questions will be approached by combining data-mining, field- and laboratory-based research, and modelling. Here, we outline the general structure of the project and the activities to be conducted within the fourteen work-packages of GLOBAQUA. Copyright © 2014. Published by Elsevier B.V.

Managing the effects of multiple stressors on aquatic ecosystems under water scarcity. The GLOBAQUA project

PubMed Central

Navarro-Ortega, Alícia; Acuña, Vicenç; Bellin, Alberto; Burek, Peter; Cassiani, Giorgio; Choukr-Allah, Redouane; Dolédec, Sylvain; Elosegi, Arturo; Ferrari, Federico; Ginebreda, Antoni; Grathwohl, Peter; Jones, Colin; Rault, Philippe Ker; Kok, Kasper; Koundouri, Phoebe; Ludwig, Ralf Peter; Merz, Ralf; Milacic, Radmila; Muñoz, Isabel; Nikulin, Grigory; Paniconi, Claudio; Paunović, Momir; Petrovic, Mira; Sabater, Laia; Sabaterb, Sergi; Skoulikidis, Nikolaos Th.; Slob, Adriaan; Teutsch, Georg; Voulvoulis, Nikolaos; Barceló, Damià

2015-01-01

Water scarcity is a serious environmental problem in many European regions, and will likely increase in the near future as a consequence of increased abstraction and climate change. Water scarcity exacerbates the effects of multiple stressors, and thus results in decreased water quality. It impacts river ecosystems, threatens the services they provide, and it will force managers and policy-makers to change their current practices. The EU-FP7 project GLOBAQUA aims at identifying the prevalence, interaction and linkages between stressors, and to assess their effects on the chemical and ecological status of freshwater ecosystems in order to improve water management practice and policies. GLOBAQUA assembles a multidisciplinary team of 21 European plus 2 non-European scientific institutions, as well as water authorities and river basin managers. The project includes experts in hydrology, chemistry, biology, geomorphology, modelling, socio-economics, governance science, knowledge brokerage, and policy advocacy. GLOBAQUA studies six river basins (Ebro, Adige, Sava, Evrotas, Anglian and Souss Massa) affected by water scarcity, and aims to answer the following questions: how does water scarcity interact with other existing stressors in the study river basins? How will these interactions change according to the different scenarios of future global change? Which will be the foreseeable consequences for river ecosystems? How will these in turn affect the services the ecosystems provide? How should management and policies be adapted to minimise the ecological, economic and societal consequences? These questions will be approached by combining data-mining, field- and laboratory-based research, and modelling. Here, we outline the general structure of the project and the activities to be conducted within the fourteen work-packages of GLOBAQUA. PMID:25005236

The Heliospheric Cataloguing, Analysis and Techniques Service (HELCATS) project

NASA Astrophysics Data System (ADS)

Barnes, D.; Harrison, R. A.; Davies, J. A.; Perry, C. H.; Moestl, C.; Rouillard, A.; Bothmer, V.; Rodriguez, L.; Eastwood, J. P.; Kilpua, E.; Gallagher, P.; Odstrcil, D.

2017-12-01

Understanding solar wind evolution is fundamental to advancing our knowledge of energy and mass transport in the solar system, whilst also being crucial to space weather and its prediction. The advent of truly wide-angle heliospheric imaging has revolutionised the study of solar wind evolution, by enabling direct and continuous observation of both transient and background components of the solar wind as they propagate from the Sun to 1 AU and beyond. The recently completed, EU-funded FP7 Heliospheric Cataloguing, Analysis and Techniques Service (HELCATS) project (1st May 2014 - 30th April 2017) combined European expertise in heliospheric imaging, built up over the last decade in particular through leadership of the Heliospheric Imager (HI) instruments aboard NASA's STEREO mission, with expertise in solar and coronal imaging as well as the interpretation of in-situ and radio diagnostic measurements of solar wind phenomena. HELCATS involved: (1) the cataloguing of transient (coronal mass ejections) and background (stream/corotating interaction regions) solar wind structures observed by the STEREO/HI instruments, including estimates of their kinematic properties based on a variety of modelling techniques; (2) the verification of these kinematic properties through comparison with solar source observations and in-situ measurements at multiple points throughout the heliosphere; (3) the assessment of the potential for initialising numerical models based on the derived kinematic properties of transient and background solar wind components; and (4) the assessment of the complementarity of radio observations (Type II radio bursts and interplanetary scintillation) in the detection and analysis of heliospheric structure in combination with heliospheric imaging observations. In this presentation, we provide an overview of the HELCATS project emphasising, in particular, the principal achievements and legacy of this unprecedented project.

EUTEMPE-RX, an EC supported FP7 project for the training and education of medical physics experts in radiology.

PubMed

Bosmans, H; Bliznakova, K; Padovani, R; Christofides, S; Van Peteghem, N; Tsapaki, V; Caruana, C J; Vassileva, J

2015-07-01

The core activity of the medical physics expert (MPE) is to ensure optimal use of ionising radiation in healthcare. It is essential that these healthcare professionals are trained to the highest level, defined as European Qualifications Framework for Lifelong Learning (EQF) level 8 by the European Commission's Radiation Protection Report 174 'Guidelines on the MPE'. The main objective of the EUTEMPE-RX project is to provide a model training scheme that allows the medical physicist in diagnostic and interventional radiology (D&IR) to reach this high level. A European network of partners was brought together in this FP7 EC project to ensure sufficient expertise in all aspects of the subject and to create a harmonised course programme. Targeted participants are medical physicists in D&IR in hospitals, engineers and scientists in medical device industries and officers working in regulatory authorities. Twelve course modules will be developed at EQF level 8, with radiation safety and diagnostic effectiveness being prevalent subjects. The modules will combine online with face-to-face teaching using a blended learning approach. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Manipulation of spin transfer torque using light

NASA Astrophysics Data System (ADS)

Rontani, Massimo; Vendelbjerg, Karsten; Sham, Lu

We show that the spin transfer torque induced by a spin-polarized current on a nanomagnet as the current flows through a semiconductor-nanomagnet-semiconductor junction is externally controlled by shining the junction off-resonantly with a strong laser beam. The excitonic coherence driven by the laser dresses the virtual electron-hole pairs coupling conduction and valence bands and inducing an evanescent state in the proximity of the nanomagnet. The Fano-like quantum interference between this localized state and the continuum spectrum is different in the two spin channels and hence it dramatically alters the spin transport, leading to the coherent control of the spin transfer torque. This work is supported by EU-FP7 Marie Curie Initial Training Network INDEX.

Land ECVs from QA4ECV using an optimal estimation framework

NASA Astrophysics Data System (ADS)

Muller, Jan-Peter; Kharbouche, Said; Lewis, Philip; Danne, Olaf; Blessing, Simon; Giering, Ralf; Gobron, Nadine; Lanconelli, Christian; Govaerts, Yves; Schulz, Joerg; Doutriaux-Boucher, Marie; Lattanzio, Alessio; Aoun, Youva

2017-04-01

In the ESA-DUE GlobAlbedo project (http://www.GlobAlbedo.org), a 15 year record of land surface albedo was generated from the European VEGETATION & MERIS sensors using optimal estimation. This was based on 3 broadbands (0.4-0.7, 0.7-3, 0.4-3µm) and fused data at level-2 after converting from spectral narrowband to these 3 broadbands with surface BRFs. A 10 year long record of land surface albedo climatology was generated from Collection 5 of the MODIS BRDF product for these same broadbands. This was employed as an a priori estimate for an optimal estimation based retrieval of land surface albedo when there were insufficient samples from the European sensors. This so-called MODIS prior was derived at 1km from the 500m MOD43A1,2 BRDF inputs every 8 days using the QA bits and the method described in the GlobAlbedo ATBD which is available from the website (http://www.globalbedo.org/docs/GlobAlbedo_Albedo_ATBD_V4.12.pdf). In the ESA-STSE WACMOS-ET project, FastOpt generated fapar & LAI based on this GlobAlbedo BRDF with associated per pixel uncertainty using the TIP framework. In the successor EU-FP7-QA4ECV* project, we have developed a 33 year record (1981-2014) of Earth surface spectral and broadband albedo (i.e. including the ocean and sea-ice) using optimal estimation for the land and where available, relevant sensors for "instantaneous" retrievals over the poles (Kharbouche & Muller, this conference). This requires the longest possible land surface spectral and broadband BRDF record that can only be supplied by a 16 year of MODIS Collection 6 BRDFs at 500m but produced on a daily basis. The CEMS Big Data computer at RAL was used to generate 7 spectral bands and 3 broadband BRDF with and without snow and snow_only. We will discuss the progress made since the start of the QA4ECV project on the production of a new fused land surface BRDF/albedo spectral and broadband CDR product based on four European sensors: MERIS, (A)ATSR(2), VEGETATION, PROBA-V and two US sensors: MISR & MODIS. For the European sensors, an uniform atmospheric correction scheme has been employed to generate spectral BRF products and these have all been mapped into MODIS spectral bands whilst the US sensors have employed their own level-2 BRF retrieval schemes with associated uncertainty information. Progress is also demonstrated on the use of TIP for fapar/LAI retrieval from the broadband BRDFs as well as fapar from AVHRR based on retrievals from MERIS and OLCI. In parallel, work has taken place at two of our partners on the production of a new geostationary broadband BRF and associated albedo and their fusion with AVHRR-LTDR for a 33 year record. QA4ECV has received funding from the European Union's Seventh Framework Programme (FP7/2007-2013) under grant agreement no. 607405

REACH-ER: a tool to evaluate river basin remediation measures for contaminants at the catchment scale

NASA Astrophysics Data System (ADS)

van Griensven, Ann; Haest, Pieter Jan; Broekx, Steven; Seuntjens, Piet; Campling, Paul; Ducos, Geraldine; Blaha, Ludek; Slobodnik, Jaroslav

2010-05-01

The European Union (EU) adopted the Water Framework Directive (WFD) in 2000 ensuring that all aquatic ecosystems meet ‘good status' by 2015. However, it is a major challenge for river basin managers to meet this requirement in river basins with a high population density as well as intensive agricultural and industrial activities. The EU financed AQUAREHAB project (FP7) specifically examines the ecological and economic impact of innovative rehabilitation technologies for multi-pressured degraded water bodies. For this purpose, a generic collaborative management tool ‘REACH-ER' is being developed that can be used by stakeholders, citizens and water managers to evaluate the ecological and economical effects of different remedial actions on waterbodies. The tool is built using databases from large scale models simulating the hydrological dynamics of the river basing and sub-basins, the costs of the measures and the effectiveness of the measures in terms of ecological impact. Knowledge rules are used to describe the relationships between these data in order to compute the flux concentrations or to compute the effectiveness of measures. The management tool specifically addresses nitrate pollution and pollution by organic micropollutants. Detailed models are also used to predict the effectiveness of site remedial technologies using readily available global data. Rules describing ecological impacts are derived from ecotoxicological data for (mixtures of) specific contaminants (msPAF) and ecological indices relating effects to the presence of certain contaminants. Rules describing the cost-effectiveness of measures are derived from linear programming models identifying the least-cost combination of abatement measures to satisfy multi-pollutant reduction targets and from multi-criteria analysis.

Citizen observatory of water as a data engine supporting the people-hydrology nexus: experience of the WeSenseIt project

NASA Astrophysics Data System (ADS)

Ferri, Michele; Baruffi, Francesco; Norbiato, Daniele; Monego, Martina; Tomei, Giovanni; Solomatine, Dimitri; Alfonso, Leonardo; Mazzoleni, Maurizio; Chacon, Juan Carlos; Wehn, Uta; Ciravegna, Fabio

2016-04-01

Citizen observatories (COs) present an interesting case of strong multi-facet feedback between the physical (water) system and humans. CO is a form of crowdsourcing ensuring a data flow from citizens observing environment (e.g. water level in a river) to a central data processing unit which is typically part of a more complex social arrangement (e.g. water authorities responsible for flood forecasting). The EU-funded project WeSenseIt (www.wesenseit.eu) aims at developing technologies and tools supporting creation of such COs [1,2,3,4]. Citizens which form a CO play the role of "social sensors" which however are very specific. The data streams from such sensors have varying temporal and spatial coverage and information value (uncertainty). The crowdsourced data can be of course simply visualized and presented to public, but it is much more interesting to consider cases when such data are assimilated into the existing forecasting systems, e.g. flood early warning systems based on hydrological and hydraulic models. COs may also affect water management and governance [4], and in fact can be seen as data engines supporting the people-hydrology nexus. In the framework of WeSenseIt project several approaches were developed allowing for optimal assimilation of intermittent data streams with varying spatial coverage into distributed hydrological models [1, 2]. The mentioned specific features of CO data required updates of the existing data assimilation algorithms (Ensemble Kalman Filter was used as the basic algorithm). The developed algorithms have been implemented in the operational flood forecasting systems of the Alto Adriatico Water Authority (AAWA), Venice. In this paper we analyse various scenarios of employing citizens data (COs) for flood forecasting. This study is partly supported by the FP7 European Project WeSenseIt Citizen Water Observatory (www.http://wesenseit.eu/). References [1] Mazzoleni, M., Alfonso, L., Chacon-Hurtado, J., Solomatine, D. (2015). Assimilating uncertain, dynamic and intermittent streamflow observations in hydrological models. Advances in Water Res., 83, 323-339 (Online on September 1, 2015). [2] Mazzoleni M., Verlaan M., Alfonso L., Monego M., Norbiato D., Ferri M., and Solomatine D.P. (2015) Can assimilation of crowdsourced streamflow observations in hydrological modelling improve flood prediction?, Hydrology and Earth System Sciences, under review. [3] Mazzoleni M., Alfonso L. and Solomatine D.P. (2015) Effect of spatial distribution and quality of sensors on the assimilation of distributed streamflow observations in hydrological modeling, Hydrological Sciences Journal, under review. [4] Wehn, U., McCarty, S., Lanfranchi, V. and Tapsell, S. (2015) Citizen observatories as facilitators of change in water governance? Experiences from three European cases, Special Issue on ICTs and Water, Journal of Environmental Engineering and Management, 2073-2086.

Estimation of desert-dust-related ice nuclei profiles from polarization lidar

NASA Astrophysics Data System (ADS)

Mamouri, Rodanthi-Elisavet; Nisantzi, Argyro; Hadjimitsis, Diofantos; Ansmann, Albert

2015-04-01

This paper presents a methodology based on the use of active remote sensing techniques for the estimation of ice nuclei concentrations (INC) for desert dust plumes. Although this method can be applied to other aerosol components, in this study we focus on desert dust. The method makes use of the polarization lidar technique for the separation of dust and non-dust contributions to the particle backscatter and extinction coefficients. The profile of the dust extinction coefficient is converted to APC280 (dust particles with radius larger than 280 nm) and, in a second step, APC280 is converted to INC by means of an APC-INC relationship from the literature. The observed close relationship between dust extinction at 500 nm and APC280 is the key to a successful INC retrieval. The correlation between dust extinction coefficient and APC280 is studied by means of AERONET sun/sky photometer at Morocco, Cape Verde, Barbados, and Cyprus, during situations dominated by desert dust outbreaks. In the present study, polarization lidar observations of the EARLINET (European Aerosol Research Lidar Network) lidar at the Cyprus University of Technology (CUT), Limassol (34.7o N, 33o E), Cyprus were used together with spaceborne lidar observations during CALIPSO satellite overpasses to demonstrate the potential of the new INC retrieval method. A good agreement between the CALIOP (Cloud Aerosol Lidar with Orthogonal Polarization) and our CUT lidar observations regarding the retrieval of dust extinction coefficient, APC280, and INC profiles were found and corroborate the potential of CALIOP to provide 3-D global desert-dust-related INC data sets. In the next step, efforts should be undertaken towards the establishment of a global, height-resolved INC climatology for desert dust plumes. Realistic global INC distributions are required for an improved estimation of aerosol effects on cloud formation and the better quantification of the indirect aerosol effect on climate. Acknowledgements. The authors thank the CUT Remote Sensing Laboratory for their support. The research leading to these results has also received scientific support from the European Union Seventh Framework Programme (FP7/2011-2015) under grant agreement no. 262254 (ACTRIS project). We acknowledge funding from the EU FP7-ENV-2013 programme "impact of Biogenic vs. Anthropogenic emissions on Clouds and Climate: towards a Holistic UnderStanding" (BACCHUS), project no. 603445. We are grateful to AERONET for high-quality sun/sky photometer measurements in Cyprus, Morocco, Cape Verde, and Barbados. We thank the NASA Langley Research Center and the CALIPSO science team for the constant effort and improvement of then CALIPSO data.

Comparison of a flexible versus a rigid breast compression paddle: pain experience, projected breast area, radiation dose and technical image quality.

PubMed

Broeders, Mireille J M; Ten Voorde, Marloes; Veldkamp, Wouter J H; van Engen, Ruben E; van Landsveld-Verhoeven, Cary; 't Jong-Gunneman, Machteld N L; de Win, Jos; Greve, Kitty Droogh-de; Paap, Ellen; den Heeten, Gerard J

2015-03-01

To compare pain, projected breast area, radiation dose and image quality between flexible (FP) and rigid (RP) breast compression paddles. The study was conducted in a Dutch mammographic screening unit (288 women). To compare both paddles one additional image with RP was made, consisting of either a mediolateral-oblique (MLO) or craniocaudal-view (CC). Pain experience was scored using the Numeric Rating Scale (NRS). Projected breast area was estimated using computer software. Radiation dose was estimated using the model by Dance. Image quality was reviewed by three radiologists and three radiographers. There was no difference in pain experience between both paddles (mean difference NRS: 0.08 ± 0.08, p = 0.32). Mean radiation dose was 4.5 % lower with FP (0.09 ± 0.01 p = 0.00). On MLO-images, the projected breast area was 0.79 % larger with FP. Paired evaluation of image quality indicated that FP removed fibroglandular tissue from the image area and reduced contrast in the clinically relevant retroglandular area at chest wall side. Although FP performed slightly better in the projected breast area, it moved breast tissue from the image area at chest wall side. RP showed better contrast, especially in the retroglandular area. We therefore recommend the use of RP for standard MLO and CC views.

Saturn and Earth polar oval position forecast by IMPEx InfrastructureWeb Services based on the Paraboloid magnetospheric model

NASA Astrophysics Data System (ADS)

Blokhina, M. S.; Alexeev, I. I.; Belenkaya, E. S.; Kalegaev, V. V.; Barinova, V. O.; Khodachenko, M. L.; Topf, F.

2012-09-01

The Saturn and Earth auroral emissions have different generation mechanisms, however, both mechanisms are not understood very well till now (see [1]). Both of these phenomena have a long history of observations. For Saturn these are Hubble images and big onground telescope images, as well as the Cassini ones in recent time. For Earth these are the satellite visible and UV camera images and onground observations. In course of the EU-FP7 Project "Integrated Medium for Planetary Exploration" the Web services based on the paraboloid magnetospheric models were constructed . The model field lines tracing gives us a possibility to distinguish the closed and open field line bundles. Additionally, we can find a boundary between the dipole type field lines and determine a region of the tail-like field lines crossing the equatorial plane tailward from the inner edge of the tail current sheet. Projections of this boundary and of the boundary between open and closed field lines at the ionospheric level mark the terrestrial auroral oval boundaries. The final result depends on the solar wind parameters and the magnetospheric state. In the Earth's case we have the ACE solar wind monitoring data which should be used to determine the magnetospheric state (http://smdc.sinp.msu.ru/index.py? nav=paraboloid/index [Interactive Earth]). For Saturn we use the three levels of the solar wind dynamic pressure (http://smdc.sinp. msu.ru/index.py?nav=paraboloid/index [Interactive Saturn]).

Climate simulations and services on HPC, Cloud and Grid infrastructures

NASA Astrophysics Data System (ADS)

Cofino, Antonio S.; Blanco, Carlos; Minondo Tshuma, Antonio

2017-04-01

Cloud, Grid and High Performance Computing have changed the accessibility and availability of computing resources for Earth Science research communities, specially for Climate community. These paradigms are modifying the way how climate applications are being executed. By using these technologies the number, variety and complexity of experiments and resources are increasing substantially. But, although computational capacity is increasing, traditional applications and tools used by the community are not good enough to manage this large volume and variety of experiments and computing resources. In this contribution, we evaluate the challenges to run climate simulations and services on Grid, Cloud and HPC infrestructures and how to tackle them. The Grid and Cloud infrastructures provided by EGI's VOs ( esr , earth.vo.ibergrid and fedcloud.egi.eu) will be evaluated, as well as HPC resources from PRACE infrastructure and institutional clusters. To solve those challenges, solutions using DRM4G framework will be shown. DRM4G provides a good framework to manage big volume and variety of computing resources for climate experiments. This work has been supported by the Spanish National R&D Plan under projects WRF4G (CGL2011-28864), INSIGNIA (CGL2016-79210-R) and MULTI-SDM (CGL2015-66583-R) ; the IS-ENES2 project from the 7FP of the European Commission (grant agreement no. 312979); the European Regional Development Fund—ERDF and the Programa de Personal Investigador en Formación Predoctoral from Universidad de Cantabria and Government of Cantabria.

Interactive video audio system: communication server for INDECT portal

NASA Astrophysics Data System (ADS)

Mikulec, Martin; Voznak, Miroslav; Safarik, Jakub; Partila, Pavol; Rozhon, Jan; Mehic, Miralem

2014-05-01

The paper deals with presentation of the IVAS system within the 7FP EU INDECT project. The INDECT project aims at developing the tools for enhancing the security of citizens and protecting the confidentiality of recorded and stored information. It is a part of the Seventh Framework Programme of European Union. We participate in INDECT portal and the Interactive Video Audio System (IVAS). This IVAS system provides a communication gateway between police officers working in dispatching centre and police officers in terrain. The officers in dispatching centre have capabilities to obtain information about all online police officers in terrain, they can command officers in terrain via text messages, voice or video calls and they are able to manage multimedia files from CCTV cameras or other sources, which can be interesting for officers in terrain. The police officers in terrain are equipped by smartphones or tablets. Besides common communication, they can reach pictures or videos sent by commander in office and they can respond to the command via text or multimedia messages taken by their devices. Our IVAS system is unique because we are developing it according to the special requirements from the Police of the Czech Republic. The IVAS communication system is designed to use modern Voice over Internet Protocol (VoIP) services. The whole solution is based on open source software including linux and android operating systems. The technical details of our solution are presented in the paper.

Validation of quality indicators for the organization of palliative care: a modified RAND Delphi study in seven European countries (the Europall project).

PubMed

Woitha, Kathrin; Van Beek, Karen; Ahmed, Nisar; Jaspers, Birgit; Mollard, Jean M; Ahmedzai, Sam H; Hasselaar, Jeroen; Menten, Johan; Vissers, Kris; Engels, Yvonne

2014-02-01

Validated quality indicators can help health-care professionals to evaluate their medical practices in a comparative manner to deliver optimal clinical care. No international set of quality indicators to measure the organizational aspects of palliative care settings exists. To develop and validate a set of structure and process indicators for palliative care settings in Europe. A two-round modified RAND Delphi process was conducted to rate clarity and usefulness of a previously developed set of 110 quality indicators. In total, 20 multi-professional palliative care teams of centers of excellence from seven European countries. In total, 56 quality indicators were rated as useful. These valid quality indicators concerned the following domains: the definition of a palliative care service (2 quality indicators), accessibility to palliative care (16 quality indicators), specific infrastructure to deliver palliative care (8 quality indicators), symptom assessment tools (1 quality indicator), specific personnel in palliative care services (9 quality indicators), documentation methodology of clinical data (14 quality indicators), evaluation of quality and safety procedures (1 quality indicator), reporting of clinical activities (1 quality indicator), and education in palliative care (4 quality indicator). The modified RAND Delphi process resulted in 56 international face-validated quality indicators to measure and compare organizational aspects of palliative care. These quality indicators, aimed to assess and improve the organization of palliative care, will be pilot tested in palliative care settings all over Europe and be used in the EU FP7 funded IMPACT project.

Using a centralised database system and server in the European Union Framework Programme 7 project SEPServer

NASA Astrophysics Data System (ADS)

Heynderickx, Daniel

2012-07-01

The main objective of the SEPServer project (EU FP7 project 262773) is to produce a new tool, which greatly facilitates the investigation of solar energetic particles (SEPs) and their origin: a server providing SEP data, related electromagnetic (EM) observations and analysis methods, a comprehensive catalogue of the observed SEP events, and educational/outreach material on solar eruptions. The project is coordinated by the University of Helsinki. The project will combine data and knowledge from 11 European partners and several collaborating parties from Europe and US. The datasets provided by the consortium partners are collected in a MySQL database (using the ESA Open Data Interface under licence) on a server operated by DH Consultancy, which also hosts a web interface providing browsing, plotting and post-processing and analysis tools developed by the consortium, as well as a Solar Energetic Particle event catalogue. At this stage of the project, a prototype server has been established, which is presently undergoing testing by users inside the consortium. Using a centralized database has numerous advantages, including: homogeneous storage of the data, which eliminates the need for dataset specific file access routines once the data are ingested in the database; a homogeneous set of metadata describing the datasets on both a global and detailed level, allowing for automated access to and presentation of the various data products; standardised access to the data in different programming environments (e.g. php, IDL); elimination of the need to download data for individual data requests. SEPServer will, thus, add value to several space missions and Earth-based observations by facilitating the coordinated exploitation of and open access to SEP data and related EM observations, and promoting correct use of these data for the entire space research community. This will lead to new knowledge on the production and transport of SEPs during solar eruptions and facilitate the development of models for predicting solar radiation storms and calculation of expected fluxes/fluences of SEPs encountered by spacecraft in the interplanetary medium.

Comparison of the Outcome of Silicone Ahmed Glaucoma Valve Implantation with a Surface Area between 96 and 184 mm2 in Adult Eyes

PubMed Central

Koh, Kyung Min; Hwang, Young Hoon; Jung, Jong Jin; Sohn, Yong Ho

2013-01-01

Purpose To compare the success rates, complications, and visual outcomes between silicone Ahmed glaucoma valve (AGV) implantation with 96 mm2 (FP8) or 184 mm2 (FP7) surface areas. Methods This study is a retrospective review of the records from 132 adult patients (134 eyes) that underwent silicone AGV implant surgery. Among them, the outcomes of 24 eyes from 24 patients with refractory glaucoma who underwent FP8 AGV implantation were compared with 76 eyes from 76 patients who underwent FP7 AGV implantation. Preoperative and postoperative data, including intraocular pressure (IOP), visual acuity, number of medications, and complications were compared between the 2 groups. Results There were no significant differences in baseline characteristics between the 2 groups (p > 0.05). The postoperative visual acuity of the patients in the FP8 group was better than that of the patients in the FP7 group in some early postoperative periods (p < 0.05); however, after 10 postoperative months, visual acuity was not significantly different through the 3-year follow-up period (p > 0.05). Postoperative IOP was not significantly different between the 2 groups (p > 0.05) except for IOP on postoperative day 1 (11.42 mmHg for the FP7 group and 7.42 mmHg for the FP8 group; p = 0.031). There was no statistical difference in success rates, final IOP, number of medications, or complication rates between the 2 groups (p > 0.05). Conclusions The FP7 and FP8 AGV implants showed no difference in terms of vision preservation, IOP reduction, and number of glaucoma medications required. PMID:24082774

Balancing the Needs between Training for Future Scientists and Broader Societal Needs--SECURE Project Research on Mathematics, Science and Technology Curricula and Their Implementation

ERIC Educational Resources Information Center

Sokolowska, D.; de Meyere, J.; Folmer, E.; Rovsek, B.; Peeters, W.

2014-01-01

SECURE is a collaborative project under FP7 to provide research results of current mathematics, science and technology (MST) curricula across Europe. The research focuses on the MST curricula offered to 5, 8, 11 and 13 year old learners in ten European countries. The consortium invited 60 schools from each partner country to participate in the…

Modelling gas transport in the shallow subsurface in the Maguelone field experiment

NASA Astrophysics Data System (ADS)

Basirat, Farzad; Niemi, Auli; Perroud, Hervé; Lofi, Johanna; Denchik, Nataliya; Lods, Gérard; Pezard, Philippe; Sharma, Prabhakar; Fagerlund, Fritjof

2013-04-01

Developing reliable monitoring techniques to detect and characterize CO2 leakage in shallow subsurface is necessary for the safety of any GCS project. To test different monitoring techniques, shallow injection-monitoring experiment have and are being carried out at the Maguelone, along the Mediterranean lido of the Gulf of Lions, near Montpellier, France. This experimental site was developed in the context of EU FP7 project MUSTANG and is documented in Lofi et al. (2012). Gas injection experiments are being carried out and three techniques of pressure, electrical resistivity and seismic monitoring have been used to detect the nitrogen and CO2 release in the near surface environment. In the present work we use the multiphase and multicomponent TOUGH2/EOS7CA model to simulate the gaseous nitrogen and CO2 transport of the experiments carried out so far. The objective is both to gain understanding of the system performance based on the model analysis as well as to further develop and validate modelling approaches for gas transport in the shallow subsurface, against the well-controlled data sets. Numerical simulation can also be used for the prediction of experimental setup limitations. We expect the simulations to represent the breakthrough time for the different tested injection rates. Based on the hydrogeological formation data beneath the lido, we also expect the vertical heterogeneities in grain size distribution create an effective capillary barrier against upward gas transport in numerical simulations. Lofi J., Pezard P.A., Bouchette F., Raynal O., Sabatier P., Denchik N., Levannier A., Dezileau L., and Certain R. Integrated onshore-offshore geophysical investigation of a layered coastal aquifer, NW Mediterranean. Ground Water, (2012).

Estimation of human damage and economic loss of buildings for the worst-credible scenario of tsunami inundation in the city of Augusta, Italy

NASA Astrophysics Data System (ADS)

Pagnoni, Gianluca; Tinti, Stefano

2017-04-01

The city of Augusta is located in the southern part of the eastern coast of Sicily. Italian tsunami catalogue and paleo-tsunami surveys indicate that at least 7 events of tsunami affected the bay of Augusta in the last 4,000 years, two of which are associated with earthquakes (1169 and 1693) that destroyed the city. For these reasons Augusta has been chosen in the project ASTARTE as a test site for the study of issues related to tsunami hazard and risk. In last two years we studied hazard through the approach of the worst-case credible scenario and carried out vulnerability and damage analysis for buildings. In this work, we integrate that research, and estimate the damage to people and the economic loss of buildings due to structural damage. As regards inundation, we assume both uniform inundation levels (bath-tub hypothesis) and inundation data resulting from the worst-case scenario elaborated for the area by Armigliato et al. (2015). Human damage is calculated in three steps using the method introduced by Pagnoni et al. (2016) following the work by Terrier et al. (2012) and by Koshimura et al. (2009). First, we use census data to estimate the number of people present in each residential building affected by inundation; second, based on water column depth and building type, we evaluate the level of damage to people; third, we provide an estimate of fatalities. The economic loss is computed for two types of buildings (residential and trade-industrial) by using data on inundation and data from the real estate market. This study was funded by the EU Project ASTARTE - "Assessment, STrategy And Risk Reduction for Tsunamis in Europe", Grant 603839, 7th FP (ENV.2013.6.4-3)

Analysis of the WRF-Chem simulations contributing to the AQMEII-Phase II exercise with respect to aerosol impact on precipitation

NASA Astrophysics Data System (ADS)

Werhahn, Johannes; Balzarini, Allessandra; Baró, Roccio; Curci, Gabriele; Forkel, Renate; Hirtl, Marcus; Honzak, Luka; Jiménez-Guerrero, Pedro; Langer, Matthias; Lorenz, Christof; Pérez, Juan L.; Pirovano, Guido; San José, Roberto; Tuccella, Paolo; Žabkar, Rahela

2014-05-01

Simulated feedback effects between aerosol concentrations and meteorological variables and on pollutant distributions are expected to depend on model configuration and the meteorological situation. In order to quantity these effects the second phase of the AQMEII (Air Quality Model Evaluation International Initiative; http://aqmeii.jrc.ec.europa.eu/) model inter-comparison exercise focused on online coupled meteorology-chemistry models. Among others, seven of the participating groups contributed simulations with WRF-Chem (Grell et al., 2005) for Europe. According to the common simulation strategy for AQMEII phase 2, the entire year 2010 was simulated as a sequence of 2-day time slices. For better comparability, the seven groups using WRF-Chem applied the same grid spacing of 23 km and shared common processing of initial and boundary conditions as well as anthropogenic and fire emissions. The simulations differ by the chosen chemistry option, aerosol module, cloud microphysics, and by the degree of aerosol-meteorology feedback that was considered. Results from this small ensemble are analyzed with respect to the effect of the different degrees of aerosol-meteorology feedback, i.e. no aerosol feedback, direct aerosol effect, and direct plus indirect aerosol effect, on large scale precipitation. Simulated precipitation fields were compared against daily precipitation observations as given by E-OBS 25 km resolution gridded dataset from the EU-FP6 project ENSEMBLES (http://ensembles-eu.metoffice.com) and the data providers in the ECA&D project (http://www.ecad.eu). As expected, a first analysis confirms that the average impact of aerosol feedback is only very small on the considered spatial and temporal scale, i.e. due to the fact that initial meteorological conditions were taken every 3rd day from a one day non-feedback spin-up run. However, the analysis of the correlations between simulation and observations for the first and the second day indicates for some particular situations and regions a slightly better correlation when the aerosol indirect effect is accounted for.

EXTraS: Exploring the X-ray Transient and variable Sky

NASA Astrophysics Data System (ADS)

De Luca, A.; Salvaterra, R.; Tiengo, A.; D'Agostino, D.; Watson, M.; Haberl, F.; Wilms, J.

2017-10-01

The EXTraS project extracted all temporal domain information buried in the whole database collected by the EPIC cameras onboard the XMM-Newton mission. This included a search and characterisation of variability, both periodic and aperiodic, in hundreds of thousands of sources spanning more than eight orders of magnitude in time scale and six orders of magnitude in flux, as well as a search for fast transients, missed by standard image analysis. Phenomenological classification of variable sources, based on X-ray and multiwavelength information, has also been performed. All results and products of EXTraS are made available to the scientific community through a web public data archive. A dedicated science gateway will allow scientists to apply EXTraS pipelines on new observations. EXTraS is the most comprehensive analysis of variability, on the largest ever sample of soft X-ray sources. The resulting archive and tools disclose an enormous scientific discovery space to the community, with applications ranging from the search for rare events to population studies, with impact on the study of virtually all astrophysical source classes. EXTraS, funded within the EU/FP7 framework, is carried out by a collaboration including INAF (Italy), IUSS (Italy), CNR/IMATI (Italy), University of Leicester (UK), MPE (Germany) and ECAP (Germany).

Stakeholder attitudes towards cumulative and aggregate exposure assessment of pesticides.

PubMed

Verbeke, Wim; Van Loo, Ellen J; Vanhonacker, Filiep; Delcour, Ilse; Spanoghe, Pieter; van Klaveren, Jacob D

2015-05-01

This study evaluates the attitudes and perspectives of different stakeholder groups (agricultural producers, pesticide manufacturers, trading companies, retailers, regulators, food safety authorities, scientists and NGOs) towards the concepts of cumulative and aggregate exposure assessment of pesticides by means of qualitative in-depth interviews (n = 15) and a quantitative stakeholder survey (n = 65). The stakeholders involved generally agreed that the use of chemical pesticides is needed, primarily for meeting the need of feeding the growing world population, while clearly acknowledging the problematic nature of human exposure to pesticide residues. Current monitoring was generally perceived to be adequate, but the timeliness and consistency of monitoring practices across countries were questioned. The concept of cumulative exposure assessment was better understood by stakeholders than the concept of aggregate exposure assessment. Identified pitfalls were data availability, data limitations, sources and ways of dealing with uncertainties, as well as information and training needs. Regulators and food safety authorities were perceived as the stakeholder groups for whom cumulative and aggregate pesticide exposure assessment methods and tools would be most useful and acceptable. Insights obtained from this exploratory study have been integrated in the development of targeted and stakeholder-tailored dissemination and training programmes that were implemented within the EU-FP7 project ACROPOLIS. Copyright © 2014 Elsevier Ltd. All rights reserved.

Near Wall Dynamics in Colloidal Suspensions Studied by Evansescent Wave Dynamic Light Scattering

NASA Astrophysics Data System (ADS)

Lang, Peter R.

2011-03-01

The dynamics of dispersed colloidal particles is slowed down, and becomes anisotropic in the ultimate vicinity of a flat wall due to the wall drag effect. Although theoretically predicted in the early 20th century, experimental verification of this effect for Brownian particles became possible only in the late 80s. Since then a variety of experimental investigations on near wall Brownian dynamics by evanescent wave dynamic light scattering (EWDLS) has been published. In this contribution the method of EWDLS will be briefly introduced, experiments at low and high colloid concentration for hard-sphere suspensions, and the theoretical prediction for measured initial slopes of correlation functions will be discussed. On increasing the particle concentration the influence of the wall drag effect is found to diminishes gradually, until it becomes negligible at volume fractions above ϕ 0.35. The effect that a wall exerts on the orientational dynamics was investigated for different kinds of colloids. Experiments, simulations and a virial expansion theory show that rotational dynamics is slowed down as well. However, the effect is prominent in EWDLS only if the particles' short axis is of the order of the evanescent wave penetration depth. The author acknowledges financial support from the EU through FP7, project Nanodirect (Grant 395 No. NMP4-SL-2008-213948).

BellHouse - a collaboration in ceramics

NASA Astrophysics Data System (ADS)

Johnstone, Rupert; Liggins, Felicity; Buontempo, Carlo; Honnor, Seth; Spencer-Mills, Jocelyn; Newton, Paula; Williams, Emily

2017-04-01

In the Spring of 2016, the UK-based arts organisation Kaleider and the EU-funded FP7 climate services project EUPORIAS made an International Commission Call inviting artists to submit ideas for playable artworks to be debuted at the EUPORIAS General Assembly at the Met Office in October 2016. We received over 60 applications worldwide and were overwhelmed with the quality of ideas. We commissioned Roop Johnstone from RAMP Ceramics to create his exquisite playable artwork - BellHouse. BellHouse is a playful, interactive sound sculpture that translated the non-verbal communication of the delegates presenting at the EUPORIAS General Assembly into the chimes of 35 bells in an opened sided house. A motion capture system devised by the Met Office Informatics Lab activated striking mechanisms associated with each ceramic bell generating a continuous chiming whilst each speaker at the 250 delegate conference presented their research. BellHouse also invited Met Office scientists to interact with it through their work. Some of our favourite data translated into sound included Mt. Etna's volcanic plumes, the European drought of 1976, the solar wind, 250 years of English and Welsh temperature and precipitation anomalies and reanalysis data based on citizen science. Here we present an exploration of the why and how of BellHouse, outlining some of our reflections on its effectiveness alongside its legacy.

An integrated multi-sensors approach for volcanic cloud retrievals and source characterization

NASA Astrophysics Data System (ADS)

Corradini, Stefano; Merucci, Luca

2017-04-01

Volcanic eruptions are one the most important sources of natural pollution. In particular the volcanic clouds represent a severe threat for aviation safety. Worldwide the volcanic activity is monitored by using satellite and ground-based instruments working at different spectral ranges, with different spatial resolutions and sensitivities. Here the complementarity between geostationary and polar satellites and ground based measurements is exploited, in order to significantly improve the volcanic cloud detection and retrievals and to fully characterize the eruption source. The integration procedure named MACE (Multi-platform volcanic Ash Cloud Estimation), has been developed during the EU-FP7 APhoRISM project aimed to develop innovative products to support the management and mitigation of the volcanic and the seismic crisis. The proposed method integrates in a novel manner the volcanic ash retrievals at the space-time scale of typical geostationary observations using both the polar satellite estimations and in-situ measurements. On MACE the typical volcanic cloud retrievals in the thermal infrared are integrated by using a wider spectral range from visible to microwave. Moreover the volcanic cloud detection is extended in case of cloudy atmosphere or steam plumes. As example, the integrated approach is tested on different recent eruptions, occurred on Etna (Italy) in 2013 and 2015 and on Calbuco (Chile) in 2015.

Cergop-2, A Multipurpose and Interdisciplinary Sensor Array For Environmental Research In Central Europe

NASA Astrophysics Data System (ADS)

Pesec, P.

The project CERGOP-2 (second phase of the Central Europe Regional Geodynamics Project)was initiated 1998, as a successor of CERGOP 1993/1998. During the follow- ing 3 years a new concept was worked out which finally was submitted for EU-support under the Sub-Programme Environment and Sustainable Development (5. FP) Octo- ber 2001. In the meanwhile the proposal received a "go" which implies a ranking in the final set of proposals forseen for eventual financial support. 14 contractors out of 13 countries contributed to the formulation of the proposal, the planned actions comprize the consolidation of the GPS-network,which covers about 15 % of the European territory, the final aim being the establishment of a velocity field which allows for the derivation of strain-fields and the monitoring of energy transfer for geodynamic studies and hazard mitigation. This paper will give an overview of the required actions and the expected results, paying special attention to near real-time information and regional geodynamic inves- tigations of seismic active regions.

Family planning offered in local welfare offices.

PubMed

1998-04-01

This article describes expanded access to family planning (FP) services through community welfare offices in Washington state, US. The government aim is to decrease unintended pregnancies and to help families achieve self-sufficiency. The staff must be sensitive and respectful of clients served. The team effort includes contacting clients in other community locations to offer FP education. The approach is characterized as "1-stop shopping" that includes FP, welfare, access to jobs, training, and medical coupons. Preventing unintended pregnancies is cost effective. A state (90%) investment of $40/person for contraceptives is good business compared to $400/person as a 50/50 state/federal investment in prenatal and delivery costs. The program began in 1992, by educating staff members in community services offices (CSOs) about FP issues. In 1994, the program hired registered nurses and nurse practitioners at CSOs to provide FP services. Almost all CSOs now have nurses, and there are 8 full exam clinics. A resource handbook for CSO workers and FP nurses was compiled by state and local FP personnel. CSOs typically assign 1 staff member to FP, usually on a part time basis. Close collaboration between nurses and CSO workers usually involves more creative strategies and outreach projects. For example, in 1 CSO in Washington, the FP worker offers contraceptive counseling, pregnancy tests, and sexually transmitted disease prevention. Contraceptives are provided at a separate time with local private providers or at health department clinics. CSOs continue to provide counseling regardless of referrals to private clinics. The project is growing and forming collaborations with other FP groups. These 1-stop sites offer accessible, familiar, and comfortable services.

Direct interaction with the public: making it a "serious game" with role playing

NASA Astrophysics Data System (ADS)

Vercelli, Samuela; Lombardi, Salvatore; Jones, David; Pearce, Jonathan; Persoglia, Sergio; De Vittor, Cinzia; Gemeni, Vassiliki; Svendsen Skriung, Camilla; Bigi, Sabina; Franzese, Carmela; Riley, Nick; McConnell, Brian; Volpi, Valentina; Donda, Federica

2014-05-01

Researchers have an important role in the societal process of understanding and evaluating new technologies, but their role is often undermined by the lack of appropriate contexts where a constructive dialogue can take place, thus leading to awareness of issues and correct perception of scientific data. In the case of geoscience the problem can be even harsher, due to the often limited education on the subject, complexity of the imaginative relationship with the underground, lack of social shared representations of key geological features. This contribution reports about an interactive session organised during the 2012 ESOF - European Science Open Forum http://esof2012.org/ for the FP7 project RISCS - 'Research into Impacts and Safety in CO2 Storage' http://www.riscs-co2.eu/ and in collaboration with the FP7 project CGS Europe http://www.cgseurope.net/ . The session saw the participation of about 100 people. The RISCS project is a European project which has explored the potential environmental impacts of the geological storage of CO2, as a technology for abating CO2 emissions. The session was meant to introduce the participants to the information produced within the RISCS project on possible impacts of CO2 on onshore and offshore ecosystems and human population. The objective was to experiment a process for facilitating, through dialogue and self-discovery, an understanding of the particular issues that need to be considered when evaluating the potential impacts of CO2 storage. It was also an opportunity to test an innovative and original format for science communication, aimed at involving a large group of participants in interactive activities with experts, based on the Role Playing Game pattern. The structure of the workshop included an exploration of participants' questions on and interest in CCS impacts, small group interaction with researchers and a final feed-back from each group to the plenary. Each group of about 10 participants was provided the opportunity to interact with scientists; written materials such as scientific brochures were made available for each participant and one computer per table. 13 researchers were present of which 2 social researchers, who managed the session. The others took turns at the tables, at regular intervals, participating to the discussion and providing information. Before the workshop, preparation activities took place through group work, to share and define the outcomes of the research, in relation to the objective of their communication to a not academic public. It was part of this work an integration function deployed by the social researchers which took into account both content and emotional aspects of communication issues. The outcomes of the workshop were twofold, on one side the participants could learn and find out about CO2 storage impact, on another side the researchers could experience themselves in a direct interaction with a variety of participants from different backgrounds and learn and get input from them for their work on such an important topic.

Projecting the Water Footprint Associated with Shale Resource Production: Eagle Ford Shale Case Study.

PubMed

Ikonnikova, Svetlana A; Male, Frank; Scanlon, Bridget R; Reedy, Robert C; McDaid, Guinevere

2017-12-19

Production of oil from shale and tight reservoirs accounted for almost 50% of 2016 total U.S. production and is projected to continue growing. The objective of our analysis was to quantify the water outlook for future shale oil development using the Eagle Ford Shale as a case study. We developed a water outlook model that projects water use for hydraulic fracturing (HF) and flowback and produced water (FP) volumes based on expected energy prices; historical oil, natural gas, and water-production decline data per well; projected well spacing; and well economics. The number of wells projected to be drilled in the Eagle Ford through 2045 is almost linearly related to oil price, ranging from 20 000 wells at $30/barrel (bbl) oil to 97 000 wells at $100/bbl oil. Projected FP water volumes range from 20% to 40% of HF across the play. Our base reference oil price of $50/bbl would result in 40 000 additional wells and related HF of 265 × 10 9 gal and FP of 85 × 10 9 gal. The presented water outlooks for HF and FP water volumes can be used to assess future water sourcing and wastewater disposal or reuse, and to inform policy discussions.

Automatic detection of surface changes on Mars - a status report

NASA Astrophysics Data System (ADS)

Sidiropoulos, Panagiotis; Muller, Jan-Peter

2016-10-01

Orbiter missions have acquired approximately 500,000 high-resolution visible images of the Martian surface, covering an area approximately 6 times larger than the overall area of Mars. This data abundance allows the scientific community to examine the Martian surface thoroughly and potentially make exciting new discoveries. However, the increased data volume, as well as its complexity, generate problems at the data processing stages, which are mainly related to a number of unresolved issues that batch-mode planetary data processing presents. As a matter of fact, the scientific community is currently struggling to scale the common ("one-at-a-time" processing of incoming products by expert scientists) paradigm to tackle the large volumes of input data. Moreover, expert scientists are more or less forced to use complex software in order to extract input information for their research from raw data, even though they are not data scientists themselves.Our work within the STFC and EU FP7 i-Mars projects aims at developing automated software that will process all of the acquired data, leaving domain expert planetary scientists to focus on their final analysis and interpretation. Moreover, after completing the development of a fully automated pipeline that processes automatically the co-registration of high-resolution NASA images to ESA/DLR HRSC baseline, our main goal has shifted to the automated detection of surface changes on Mars. In particular, we are developing a pipeline that uses as an input multi-instrument image pairs, which are processed by an automated pipeline, in order to identify changes that are correlated with Mars surface dynamic phenomena. The pipeline has currently been tested in anger on 8,000 co-registered images and by the time of DPS/EPSC we expect to have processed many tens of thousands of image pairs, producing a set of change detection results, a subset of which will be shown in the presentation.The research leading to these results has received funding from the STFC "MSSL Consolidated Grant under "Planetary Surface Data Mining" ST/K000977/1 and partial support from the European Union's Seventh Framework Programme (FP7/2007-2013) under iMars grant agreement number 607379

SUNLAB - The Project of a Polish Underground Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kisiel, J.; Dorda, J.; Konefall, A.

2010-11-24

The project of the first Polish underground laboratory SUNLAB, in the Polkowice-Sieroszowice copper mine, belonging to the KGHM Polska Miedz S.A. holding, is presented. Two stages of the project are foreseen: SUNLAB1 (a small laboratory in the salt layer exhibiting extremely low level of natural radioactivity) and SUNLAB2 (a big laboratory in the anhydrite layer, able to host the next generation liquid argon detector - GLACIER, which is considered within the LAGUNA FP7 project). The results of the natural radioactivity background measurements performed in the Polkowice-Sieroszowice salt cavern are also briefly summarized.

SUNLAB-The Project of a Polish Underground Laboratory

NASA Astrophysics Data System (ADS)

Kisiel, J.; Budzanowski, M.; Chorowski, M.; Cygan, S.; Dorda, J.; Hanzel, S.; Harańczyk, M.; Horoszczak, L.; Januszewska, K.; Jaroń, L.; Konefalł, A.; Kozak, K.; Lankof, L.; Mania, S.; Markiewicz, A.; Markowski, P.; Mazur, J.; Mertuszka, P.; Mietelski, J. W.; Poliński, J.; Puchalska, M.; Pytel, W.; Raczyński, M.; Sadecki, Z.; Sadowski, A.; Ślizowski, J.; Sulej, R.; Szarska, M.; Szeglowski, T.; Tomankiewicz, E.; Urbańczyk, K.; Zalewska, A.

2010-11-01

The project of the first Polish underground laboratory SUNLAB, in the Polkowice-Sieroszowice copper mine, belonging to the KGHM Polska Miedź S.A. holding, is presented. Two stages of the project are foreseen: SUNLAB1 (a small laboratory in the salt layer exhibiting extremely low level of natural radioactivity) and SUNLAB2 (a big laboratory in the anhydrite layer, able to host the next generation liquid argon detector-GLACIER, which is considered within the LAGUNA FP7 project). The results of the natural radioactivity background measurements performed in the Polkowice-Sieroszowice salt cavern are also briefly summarized.

European Virtual Atomic And Molecular Data Center - VAMDC

NASA Astrophysics Data System (ADS)

Dimitrijevic, M. S.; Sahal-Brechot, S.; Kovacevic, A.; Jevremovic, D.; Popovic, L. C.

2010-07-01

Reliable atomic and molecular data are of great importance for different applications in astrophysics, atmospheric physics, fusion, environmental sciences, combustion chemistry, and in industrial applications from plasmas and lasers to lighting. Currently, very important resources of such data are highly fragmented, presented in different, nonstandardized ways, available through a variety of highly specialized and often poorly documented interfaces, so that the full exploitation of all their scientific worth is limited, hindering research in many topics like e.g. the characterization of extrasolar planets, understanding the chemistry of our local solar system and of the wider universe, the study of the terrestrial atmosphere and quantification of climate change; the development of the fusion rersearch, etc. The Virtual Atomic and Molecular Data Centre (http://www.vamdc.eu, VAMDC) is an European Union funded FP7 project aiming to build a secure, documented, flexible and interoperable e-science environment-based interface to existing atomic and molecular data. It will also provide a forum for training potential users and dissemination of expertise worldwide. Partners in the Consortium of the Project are: 1) Centre National de Recherche Scientifique - CNRS (Paris, Reims, Grenoble, Bordeaux, Dijon, Toulouse); 2) The Chancellor, Masters and Scholars of the University of Cambridge - CMSUC; 3) University College London - UCL; 4) Open University - OU; (Milton Keynes, England); 5) Universitaet Wien - UNIVIE; 6) Uppsala Universitet - UU; 7) Universitaet zu Koeln - KOLN; 8) Istituto Nazionale di Astrofisica - INAF (Catania, Cagliari); 9) Queen's University Belfast - QUB; 10) Astronomska Opservatorija - AOB (Belgrade, Serbia); 11) Institute of Spectroscopy RAS - ISRAN (Troitsk, Russia); 12) Russian Federal Nuclear Center - All-Russian Institute of Technical Physics - RFNC-VNIITF (Snezhinsk, Chelyabinsk Region, Russia; 13) Institute of Atmospheric Optics - IAO (Tomsk, Russia); 14) Corporacion Parque tecnologico de Merida - IVIC (Merida, Venezuela); 15) Institute for Astronomy RAS - INASAN (Moscow, Russia). This review describes the VAMDC project and its objectives.

Validating GEOV3 LAI, FAPAR and vegetation cover estimates derived from PROBA-V observations at 333m over Europe

NASA Astrophysics Data System (ADS)

Camacho, Fernando; Sánchez, Jorge; Lacaze, Roselyne; Weiss, Marie; Baret, Frédéric; Verger, Aleixandre; Smets, Bruno; Latorre, Consuelo

2016-04-01

The Copernicus Global Land Service (http://land.copernicus.eu/global/) is delivering surface biophysical products derived from satellite observations at global scale. Fifteen years of LAI, FAPAR, and vegetation cover (FCOVER) products among other indicators have been generated from SPOT/VGT observations at 1 km spatial resolution (named GEOV1, GEOV2). The continuity of the service since the end of SPOT/VGT mission (May, 2014) is achieved thanks to PROBA-V, which offers observations at a finer spatial resolution (1/3 km). In the context of the FP7 ImagineS project (http://fp7-imagines.eu/), a new algorithm (Weiss et al., this conference), adapted to PROBA-V spectral and spatial characteristics, was designed to provide vegetation products (named GEOV3) as consistent as possible with GEOV1 and GEOV2 whilst providing near real-time estimates required by some users. It is based on neural network techniques completed with a data filtering and smoothing process. The near real-time estimates are improved through a consolidation period of six dekads during which observations are accumulated every new dekad. The validation of these products is mandatory to provide associated uncertainties for efficient use of this source of information. This work presents an early validation over Europe of the GEOV3 LAI, FAPAR and vegetation cover (FCOVER) products derived from PROBA-V observation at 333 m and 10-days frequency during the year 2014. The validation has been conducted in agreement with the CEOS LPV best practices for global LAI products. Several performance criteria were investigated for the several GEOV3 modes (near real-time, and successive consolidated estimates) including completeness, spatial and temporal consistency, precision and accuracy. The spatial and temporal consistency was evaluated using as reference PROBA-V GEOV1 and MODC5 1 km similar products using a network of 153 validation sites over Europe (EUVAL). The accuracy was assessed with concomitant data collected in the ImagineS project over six cropland sites located in Spain, Italy, Ukraine and Tunisia and non-concomitant data over forest sites made available through the CEOS OLIVE cal/val tool. The ground data was estimated from digital hemispherical photography following a well-established protocol over a sampling unit, and then sampling unit values were up-scaled using Landsat-8 imagery and a robust linear regression algorithm. The accuracy was estimated at 333m over regions of 20x20 km2, and at 1 km over areas of 3x3 km2 in order to compare with GEOV1 and MODIS satellite products. Our results show that GEOV3 presents good quality in most of the examined criteria, even if the near real-time estimates show a much lower precision and temporal stability in some biomes. However, after only two dekads the GEOV3 estimate becomes very stable. We observed a slight positive bias at the start of the season in croplands and deciduous forest, mainly, that could be introduced due to the smoothing process. The comparison with ground measurements showed that, overall, the accuracy was good for LAI (RMSE=0.7) and FAPAR (RMSE=0.05) with no bias in the estimates, whilst FCOVER shows a systematic overestimation of about 0.12 units.

Progress on Optimizing Miscanthus Biomass Production for the European Bioeconomy: Results of the EU FP7 Project OPTIMISC.

PubMed

Lewandowski, Iris; Clifton-Brown, John; Trindade, Luisa M; van der Linden, Gerard C; Schwarz, Kai-Uwe; Müller-Sämann, Karl; Anisimov, Alexander; Chen, C-L; Dolstra, Oene; Donnison, Iain S; Farrar, Kerrie; Fonteyne, Simon; Harding, Graham; Hastings, Astley; Huxley, Laurie M; Iqbal, Yasir; Khokhlov, Nikolay; Kiesel, Andreas; Lootens, Peter; Meyer, Heike; Mos, Michal; Muylle, Hilde; Nunn, Chris; Özgüven, Mensure; Roldán-Ruiz, Isabel; Schüle, Heinrich; Tarakanov, Ivan; van der Weijde, Tim; Wagner, Moritz; Xi, Qingguo; Kalinina, Olena

2016-01-01

This paper describes the complete findings of the EU-funded research project OPTIMISC, which investigated methods to optimize the production and use of miscanthus biomass. Miscanthus bioenergy and bioproduct chains were investigated by trialing 15 diverse germplasm types in a range of climatic and soil environments across central Europe, Ukraine, Russia, and China. The abiotic stress tolerances of a wider panel of 100 germplasm types to drought, salinity, and low temperatures were measured in the laboratory and a field trial in Belgium. A small selection of germplasm types was evaluated for performance in grasslands on marginal sites in Germany and the UK. The growth traits underlying biomass yield and quality were measured to improve regional estimates of feedstock availability. Several potential high-value bioproducts were identified. The combined results provide recommendations to policymakers, growers and industry. The major technical advances in miscanthus production achieved by OPTIMISC include: (1) demonstration that novel hybrids can out-yield the standard commercially grown genotype Miscanthus x giganteus; (2) characterization of the interactions of physiological growth responses with environmental variation within and between sites; (3) quantification of biomass-quality-relevant traits; (4) abiotic stress tolerances of miscanthus genotypes; (5) selections suitable for production on marginal land; (6) field establishment methods for seeds using plugs; (7) evaluation of harvesting methods; and (8) quantification of energy used in densification (pellet) technologies with a range of hybrids with differences in stem wall properties. End-user needs were addressed by demonstrating the potential of optimizing miscanthus biomass composition for the production of ethanol and biogas as well as for combustion. The costs and life-cycle assessment of seven miscanthus-based value chains, including small- and large-scale heat and power, ethanol, biogas, and insulation material production, revealed GHG-emission- and fossil-energy-saving potentials of up to 30.6 t CO 2eq C ha -1 y -1 and 429 GJ ha -1 y -1 , respectively. Transport distance was identified as an important cost factor. Negative carbon mitigation costs of -78€ t -1 CO 2eq C were recorded for local biomass use. The OPTIMISC results demonstrate the potential of miscanthus as a crop for marginal sites and provide information and technologies for the commercial implementation of miscanthus-based value chains.

Progress on Optimizing Miscanthus Biomass Production for the European Bioeconomy: Results of the EU FP7 Project OPTIMISC

PubMed Central

Lewandowski, Iris; Clifton-Brown, John; Trindade, Luisa M.; van der Linden, Gerard C.; Schwarz, Kai-Uwe; Müller-Sämann, Karl; Anisimov, Alexander; Chen, C.-L.; Dolstra, Oene; Donnison, Iain S.; Farrar, Kerrie; Fonteyne, Simon; Harding, Graham; Hastings, Astley; Huxley, Laurie M.; Iqbal, Yasir; Khokhlov, Nikolay; Kiesel, Andreas; Lootens, Peter; Meyer, Heike; Mos, Michal; Muylle, Hilde; Nunn, Chris; Özgüven, Mensure; Roldán-Ruiz, Isabel; Schüle, Heinrich; Tarakanov, Ivan; van der Weijde, Tim; Wagner, Moritz; Xi, Qingguo; Kalinina, Olena

2016-01-01

This paper describes the complete findings of the EU-funded research project OPTIMISC, which investigated methods to optimize the production and use of miscanthus biomass. Miscanthus bioenergy and bioproduct chains were investigated by trialing 15 diverse germplasm types in a range of climatic and soil environments across central Europe, Ukraine, Russia, and China. The abiotic stress tolerances of a wider panel of 100 germplasm types to drought, salinity, and low temperatures were measured in the laboratory and a field trial in Belgium. A small selection of germplasm types was evaluated for performance in grasslands on marginal sites in Germany and the UK. The growth traits underlying biomass yield and quality were measured to improve regional estimates of feedstock availability. Several potential high-value bioproducts were identified. The combined results provide recommendations to policymakers, growers and industry. The major technical advances in miscanthus production achieved by OPTIMISC include: (1) demonstration that novel hybrids can out-yield the standard commercially grown genotype Miscanthus x giganteus; (2) characterization of the interactions of physiological growth responses with environmental variation within and between sites; (3) quantification of biomass-quality-relevant traits; (4) abiotic stress tolerances of miscanthus genotypes; (5) selections suitable for production on marginal land; (6) field establishment methods for seeds using plugs; (7) evaluation of harvesting methods; and (8) quantification of energy used in densification (pellet) technologies with a range of hybrids with differences in stem wall properties. End-user needs were addressed by demonstrating the potential of optimizing miscanthus biomass composition for the production of ethanol and biogas as well as for combustion. The costs and life-cycle assessment of seven miscanthus-based value chains, including small- and large-scale heat and power, ethanol, biogas, and insulation material production, revealed GHG-emission- and fossil-energy-saving potentials of up to 30.6 t CO2eq C ha−1y−1 and 429 GJ ha−1y−1, respectively. Transport distance was identified as an important cost factor. Negative carbon mitigation costs of –78€ t−1 CO2eq C were recorded for local biomass use. The OPTIMISC results demonstrate the potential of miscanthus as a crop for marginal sites and provide information and technologies for the commercial implementation of miscanthus-based value chains. PMID:27917177

Disentangling the effects of climate variability and functional change on ecosystem carbon dynamics using semi-empirical modelling

NASA Astrophysics Data System (ADS)

Wu, J.; van der Linden, L.; Lasslop, G.; Carvalhais, N.; Pilegaard, K.; Beier, C.; Ibrom, A.

2012-04-01

The ecosystem carbon balance is affected by both external climatic forcing (e.g. solar radiation, air temperature and humidity) and internal dynamics in the ecosystem functional properties (e.g. canopy structure, leaf photosynthetic capacity and carbohydrate reserve). In order to understand to what extent and at which temporal scale, climatic variability and functional changes regulated the interannual variation (IAV) in the net ecosystem exchange of CO2 (NEE), data-driven analysis and semi-empirical modelling (Lasslop et al. 2010) were performed based on a 13 year NEE record in a temperate deciduous forest (Pilegaard et al 2011, Wu et al. 2012). We found that the sensitivity of carbon fluxes to climatic variability was significantly higher at shorter than at longer time scales and changed seasonally. This implied that the changing distribution of climate anomalies during the vegetation period could have stronger impacts on future ecosystem carbon balances than changes in average climate. At the annual time scale, approximately 80% of the interannual variability in NEE was attributed to the variation in the model parameters, indicating the observed IAV in the carbon dynamics at the investigated site was dominated by changes in ecosystem functioning. In general this study showed the need for understanding the mechanisms of ecosystem functional change. The method can be applied at other sites to explore ecosystem behavior across different plant functional types and climate gradients. Incorporating ecosystem functional change into process based models will reduce the uncertainties in long-term predictions of ecosystem carbon balances in global climate change projections. Acknowledgements. This work was supported by the EU FP7 project CARBO-Extreme, the DTU Climate Centre and the Danish national project ECOCLIM (Danish Council for Strategic Research).

Monitoring of the risk of farmland abandonment as an efficient tool to assess the environmental and socio-economic impact of the Common Agriculture Policy

NASA Astrophysics Data System (ADS)

Milenov, Pavel; Vassilev, Vassil; Vassileva, Anna; Radkov, Radko; Samoungi, Vessela; Dimitrov, Zlatomir; Vichev, Nikola

2014-10-01

Farmland abandonment (FLA) could be defined as the cessation of agricultural activities on a given surface of land (Pointereau et al., 2008). FLA, often associated with social and economic problems in rural areas, has significant environmental consequences. During the 1990s, millions of hectares of farmland in the new EU Member States, from Central and Eastern Europe, were abandoned as a result of the transition process from centralized and planned to market economy. The policy tools adopted gradually within the Common Agricultural Policy of the European Union (EU CAP), as well as the EU environmental and structural policies, aimed to prevent further expansion of this phenomenon and to facilitate the revival of the agriculture land, being abandoned (ComReg 1122/2009). The Agri-Environment (AGRI-ENV) component of the Core Information Service (CIS), developed within the scope of the FP7-funded project "geoland2" were designed to support the agricultural user community at pan-European and national levels by contributing to the improvement of more accurate and timely monitoring of the status of agricultural land use in Europe and its change. The purpose of the product 'Farmland abandonment', as part of the AGRI-ENV package, is to detect potentially abandoned agriculture land, based on multi-annual SPOT data with several acquisitions per year. It provides essential independent information on the status of the agricultural land as recorded in the Land Parcel Identification System (LPIS), which is one of the core instruments of the implementation of CAP. The production line is based on object-based image analysis and benefits from the extensive availability of Biophysical parameters derived from the satellite data (geoland2). The method detects/tracks those land (or so-called reference) parcels in the LPIS, holding significant amount of land agriculture found as potentially abandoned. Reference parcels with such change are flagged and reported, enabling the National Administrations to further analyze the spatial distribution and magnitude of this phenomenon at regional and national levels. Test results have been successfully generated for one test area (the Bulgarian part of the Strymunas-Struma River Basin).

Teaching Chemistry about "Stevia"--A Case of Cooperative Curriculum Innovation within PROFILES in Germany

ERIC Educational Resources Information Center

Stuckey, Marc; Lippel, Marianne; Eilks, Ingo

2014-01-01

PROFILES is a project of teacher education and curriculum innovation funded by the FP7-programme of the European Union. The aim of PROFILES is implementing innovative science teaching practices incorporating a societal perspective and compassing inquiry-based science learning. The University of Bremen, Germany, as one of the partners, combines…

The HEALTHGRAIN definition of ‘whole grain’

PubMed Central

van der Kamp, Jan Willem; Poutanen, Kaisa; Seal, Chris J.; Richardson, David P.

2014-01-01

Most cereal products, like white bread, pasta, and biscuits, are based on flour after removal of bran and germ, the two parts of grain kernels containing most of the dietary fibre and other bioactive components. In the past decade, consumers have been rediscovering whole grain-based products and the number of wholegrain products has increased rapidly. In most countries in Europe and worldwide, however, no legally endorsed definition of wholegrain flour and products exists. Current definitions are often incomplete, lacking descriptions of the included grains and the permitted flour manufacturing processes. The consortium of the HEALTHGRAIN EU project (FP6-514008, 2005–2010) identified the need for developing a definition of whole grain with the following scope: 1) more comprehensive than current definitions in most EU countries; 2) one definition for Europe – when possible equal to definitions outside Europe; 3) reflecting current industrial practices for production of flours and consumer products; 4) useful in the context of nutritional guidelines and for labelling purposes. The definition was developed in a range of discussion meetings and consultations and was launched in 2010 at the end of the HEALTHGRAIN project. The grains included are specified: a wide range of cereal grains from the Poaceae family, and the pseudo-cereals amaranth, buckwheat, quinoa, and wild rice. The definition also describes manufacturing processes allowed for producing wholegrain flours. This paper compares the HEALTHGRAIN definition with previous definitions, provides more comprehensive explanations than in the definition itself regarding the inclusion of specific grains, and sets out the permitted flour manufacturing processes. PMID:24505218

Instrumentation and monitoring of the nextgen road infrastructure: Some results and perspectives from the R5G project

NASA Astrophysics Data System (ADS)

Hautière, Nicolas; Bourquin, Frédéric

2017-04-01

Through the centuries, the roads - which today constitute in France a huge transport network of 1 millions kilometers length - have always been able to cope with society needs and challenges. As a consequence, the next generation road infrastructure will have to take into account at least three societal transitions: ecological, energetic and digital. The goal of the 5th generation road project (R5G©) [1], led by Ifsttar in France, aligned with the Forever Open program [2], is to design and build demonstrators of such future road infrastructures. The goal of this presentation is to present different results related to the greening of road materials [3], the design of energy-positive roads [4, 5], the test of roads that self-diagnose [6], the design of roads adapted for connected [7], autonomous [8] and electrified vehicles [9], etc. In terms of perspectives, we will demonstrate that the road infrastructures will soon become a complex system: On one side road users will benefit from new services, on the other side such massively connected and instrumented infrastructures will potentially become an opportune sensor for knowledge development in geoscience, such as air quality, visibility and fog monitoring. References: [1] R5G project. r5g.ifsttar.fr [2] Forever Open Road project. www.foreveropenroad.eu [3] Biorepavation project. www.infravation.net/projects/BIOREPAVATION [4] N. Le Touz, J. Dumoulin. Numerical study of the thermal behavior of a new deicing road structure design with energy harvesting capabilities. EGU General Assembly 2015, Apr 2015, Vienne, Austria. [5] S. Asfour, F. Bernardin, E. Toussaint, J.-M. Piau. Hydrothermal modeling of porous pavement for its surface de-freezing. Applied Thermal Engineering. Volume 107, 25 August 2016, Pages 493-500 [6] LGV BPL Instrumentation. http://railenium.eu/wp-content/uploads/2016/08/INSTRUMENTATION-BPL-FR.pdf [7] SCOOP@F project. https://ec.europa.eu/inea/en/connecting-europe-facility/cef-transport/projects-by-country/multi-country/2014-eu-ta-0669-s [8] J. Ehrlich, D. Gruyer, O. Orfila, N. Hautière. Autonomous vehicle : The concept of high quality of service highway. FISITA World congress, Busan, Korea, 2016. [9] FABRIC project. www.fabric-project.eu

Management tools for R&D engineering projects: Coordination perspective for large international consortium (NeXOS)

NASA Astrophysics Data System (ADS)

Castro, Ayoze; Memè, Simone; Quevedo, Eduardo; Waldmann, Christoph; Pearlman, Jay; Delory, Eric; Llinás, Octavio

2017-04-01

NeXOS is a cross-functional and multidisciplinary project funded under the EU FP7 Program, which involves 21 organizations from six different European countries. They all have different backgrounds, interests, business models and perspectives. To be successful, NeXOS applied an international recognized management methodology tailored to the specific project's environment and conditions, with an explicit structure based on defined roles and responsibilities for the people involved in the project and a means for effective communication between them (Fig.1). The project, divided in four different stages of requirements, design, integration, validation and demonstration, allows a clearer monitor of its progress, a comparison of the level of achievement in accordance with the plan and an earlier detection of problems/issues, leading to implementation of less disruptive, but still effective corrective actions. NeXOS is following an ambitious plan to develop innovative sensor systems with a high degree of modularity and interoperability, starting with requirements definition through validation and demonstration phase. To make this integrative approach possible, a management development strategy has been used incorporating systems engineering methods (Fig.2). Although this is standard practice in software development and large scale systems such as aircraft production, it is still new in the ocean hardware business and therefore NeXOS was a test case for this development concept. The question is one of scale as ocean observation systems are typically built on the scale of a few with co-located teams. With a system of diverse technologies (optical, acoustic, platform interfaces), there are cultural differences that must be bridged. The greatest challenge is in the implementation and the willingness of different teams to work with an engineering process, which may help ultimate system integration, but may place additional burdens on individual participants. This presentation will address approaches for effective operations in this environment.

Matrix-Assisted Plasma Atomization Emission Spectrometry for Surface Sampling Elemental Analysis

PubMed Central

Yuan, Xin; Zhan, Xuefang; Li, Xuemei; Zhao, Zhongjun; Duan, Yixiang

2016-01-01

An innovative technology has been developed involving a simple and sensitive optical spectrometric method termed matrix-assisted plasma atomization emission spectrometry (MAPAES) for surface sampling elemental analysis using a piece of filter paper (FP) for sample introduction. MAPAES was carried out by direct interaction of the plasma tail plume with the matrix surface. The FP absorbs energy from the plasma source and releases combustion heating to the analytes originally present on its surface, thus to promote the atomization and excitation process. The matrix-assisted plasma atomization excitation phenomenon was observed for multiple elements. The FP matrix served as the partial energy producer and also the sample substrate to adsorb sample solution. Qualitative and quantitative determinations of metal ions were achieved by atomic emission measurements for elements Ba, Cu, Eu, In, Mn, Ni, Rh and Y. The detection limits were down to pg level with linear correlation coefficients better than 0.99. The proposed MAPAES provides a new way for atomic spectrometry which offers advantages of fast analysis speed, little sample consumption, less sample pretreatment, small size, and cost-effective. PMID:26762972

A Hybrid Monte Carlo importance sampling of rare events in Turbulence and in Turbulent Models

NASA Astrophysics Data System (ADS)

Margazoglou, Georgios; Biferale, Luca; Grauer, Rainer; Jansen, Karl; Mesterhazy, David; Rosenow, Tillmann; Tripiccione, Raffaele

2017-11-01

Extreme and rare events is a challenging topic in the field of turbulence. Trying to investigate those instances through the use of traditional numerical tools turns to be a notorious task, as they fail to systematically sample the fluctuations around them. On the other hand, we propose that an importance sampling Monte Carlo method can selectively highlight extreme events in remote areas of the phase space and induce their occurrence. We present a brand new computational approach, based on the path integral formulation of stochastic dynamics, and employ an accelerated Hybrid Monte Carlo (HMC) algorithm for this purpose. Through the paradigm of stochastic one-dimensional Burgers' equation, subjected to a random noise that is white-in-time and power-law correlated in Fourier space, we will prove our concept and benchmark our results with standard CFD methods. Furthermore, we will present our first results of constrained sampling around saddle-point instanton configurations (optimal fluctuations). The research leading to these results has received funding from the EU Horizon 2020 research and innovation programme under Grant Agreement No. 642069, and from the EU Seventh Framework Programme (FP7/2007-2013) under ERC Grant Agreement No. 339032.

Identifying hotspots of coastal risk and evaluating DRR measures: results from the RISC-KIT project.

NASA Astrophysics Data System (ADS)

Van Dongeren, A.; Ciavola, P.; Viavattene, C.; Dekleermaeker, S.; Martinez, G.; Ferreira, O.; Costa, C.

2016-02-01

High-impact storm events have demonstrated the vulnerability of coastal zones in Europe and beyond. These impacts are likely to increase due to predicted climate change and ongoing coastal development. In order to reduce impacts, disaster risk reduction (DRR) measures need to be taken, which prevent or mitigate the effects of storm events. To drive the DRR agenda, the UNISDR formulated the Sendai Framework for Action, and the EU has issued the Floods Directive. However, neither is specific about the methods to be used to develop actionable DRR measures in the coastal zone. Therefore, there is a need to develop methods, tools and approaches which make it possible to: identify and prioritize the coastal zones which are most at risk through a Coastal Risk Assessment Framework, evaluate the effectiveness of DRR options for these coastal areas, using an Early Warning/Decision Support System, which can be used both in the planning and event-phase. This paper gives an overview of the products and results obtained in the FP7-funded project RISC-KIT, which aims to develop and apply a set of tools with which highly-vulnerable coastal areas (so-called "hotspots") can be identified. The identification is done using the Coastal Risk Assessment Framework, or CRAF, which computes the intensity from multi-hazards, the exposure and the vulnerability, all components of risk, including network and cascading effects. Based on this analysis hot spots of risk which warrant coastal protection investments are selected. For these hotspot areas, high-resolution Early Warning and Decision Support Tools are developed with which it is possible to compute in detail the effectiveness of Disaster Risk Reduction measures in storm event scenarios, which helps decide which measures to implement in the planning phase. The same systems, but now driven with real time data, can also be used for early warning systems. All tools are tested on eleven case study areas, at least one on each EU Regional Sea, and one international case in Bangladesh. Promising DRR measures and experiences are collected in a web-based Management Guide, and information on storm impacts is stored in a Coastal Risk Database.

EMSO ERIC - Ocean Consortium Facility for Europe and the World

NASA Astrophysics Data System (ADS)

Best, Mairi

2017-04-01

EMSO is forging ahead through the next challenge in Earth-Ocean Science: How to co-ordinate ocean data acquisition, analysis and response across provincial, national, regional, and global scales. EMSO provides power, communications, sensors, and data infrastructure for continuous, high resolution, real-time, interactive ocean observations across a truly multi- and interdisciplinary range of research areas including biology, geology, chemistry, physics, engineering, and computer science; from polar to tropical environments, through the water column down to the abyss. 11 deep sea and 4 shallow nodes span from Arctic through the Atlantic and Mediterranean, to the Black Sea. The EMSO Preparatory Phase (FP7) project led to the Interim phase (involving 13 countries) of forming the legal entity: the EMSO European Research Infrastructure Consortium (EMSO-ERIC)-officially created by the EC in 2016. The open user community, originally developed through ESONET (European Seafloor Observatory NETwork), follows on scientific community planning contributions of the ESONET-NoE (FP6) project. Further progress made through the FixO3 project (FP7) also contributes to this shared infrastructure. Coordination among nodes is being strengthened through the EMSOdev project (H2020) which is producing the EMSO Generic Instrument Module (EGIM) - standardised observations of temperature, pressure, salinity, dissolved oxygen, turbidity, chlorophyll fluorescence, currents, passive acoustics, pH, pCO2, and nutrients. Early installations are now being upgraded; in October 2015 EMSO-France deployed a second cable and junction box serving the Ligurian Sea Node in order to monitor slope stability offshore Nice; in 2016 the EMSO Azores Node receives a major upgrade that will double its observing capacity; for EMSO-Italia the Capo Passero site is being installed and the Catania site is being upgraded. EMSOLINK will continue the expansion work. EMSO is a key player in international coordination projects such as CoopEUS/Coop+, ENVRI/ENVRIplus, GOOS/EOOS - as such EMSO not only brings together countries and disciplines, but allows the pooling of resources and coordination to assemble harmonised data into a comprehensive regional ocean picture which it will then make available to researchers and stakeholders worldwide on an open and interoperable access basis.

Climate change impacts on forest fires: the stakeholders' perspective

NASA Astrophysics Data System (ADS)

Giannakopoulos, C.; Roussos, A.; Karali, A.; Hatzaki, M.; Xanthopoulos, G.; Chatzinikos, E.; Fyllas, N.; Georgiades, N.; Karetsos, G.; Maheras, G.; Nikolaou, I.; Proutsos, N.; Sbarounis, T.; Tsaggari, K.; Tzamtzis, I.; Goodess, C.

2012-04-01

In this work, we present a synthesis of the presentations and discussions which arose during a workshop on 'Impacts of climate change on forest fires' held in September 2011 at the National Observatory of Athens, Greece in the framework of EU project CLIMRUN. At first, a general presentation about climate change and extremes in the Greek territory provided the necessary background to the audience and highlighted the need for data and information exchange between scientists and stakeholders through climate services within CLIMRUN. Discussions and presentations that followed linked climate with forest science through the use of a meteorological index for fire risk and future projections of fire danger using regional climate models. The current situation on Greek forests was also presented, as well as future steps that should be taken to ameliorate the situation under a climate change world. A time series analysis of changes in forest fires using available historical data on forest ecosystems in Greece was given in this session. This led to the topic of forest fire risk assessment and fire prevention, stating all actions towards sustainable management of forests and effective mechanisms to control fires under climate change. Options for a smooth adaptation of forests to climate change were discussed together with the lessons learned on practical level on prevention, repression and rehabilitation of forest fires. In between there were useful interventions on sustainable hunting and biodiversity protection and on climate change impacts on forest ecosystems dynamics. The importance of developing an educational program for primary/secondary school students on forest fire management was also highlighted. The perspective of forest stakeholders on climate change and how this change can affect their current or future activities was addressed through a questionnaire they were asked to complete. Results showed that the majority of the participants consider climate variability to be important or very important and to influence their activities. Extreme climate events, desertification and drought were regarded as the most important environmental problems along with loss of biodiversity. Most of the participants answered that they use historical data for research, and would welcome climate data and services targeted to their sector if offered. Acknowledgement: This work was supported by the EU project CLIMRUN under contract FP7-ENV-2010- 265192.

Towards an integrated assessment of the impacts of forest residue mulching following wildfire in eucalypt plantations in north-central Portugal

NASA Astrophysics Data System (ADS)

Keizer, Jan Jacob; Abrantes, Nelson; Bastos, Ana; Brandsma, Micha; Campos, Isabel; Faria, Silvia; Malvar, Maruxa; Martins, Martinho; João Oliveira, Maria; Pimpão, Gabriel; Prats, Sergio; Puga, João; Ribeiro, Cristina; Rocha, João; Santos, Liliana; Serpa, Dalila; Silva, Flávio; Silva, Tiago; Valente, Sandra; Vieira, Diana

2016-04-01

In the framework of the EU-FP7 project RECARE (www.recare-project.eu) and, in particular, its WP6, the University of Aveiro partner has recently started testing two measures against the soil threat of post-fire erosion by water in an area in north-central Portugal, close to Coimbra that burnt during the summer of 2015. These measures - mulching with forest slash residues and contour ploughing - had been selected by the local and external stakeholders involved in the project, through two subsequent stakeholder workshops. While contour ploughing has still not taken place, the mulching was already carried out, using residues from eucalypt plantations as the burnt areas was dominated by eucalypt plantations, and applying them in a homogeneous fashion at two contrasting application rates, i.e. a "standard" rate of approximately 10 Mg ha-1 and a "reduced" rate of about 3 Mg ha-1. The standard rate was selected for having proved effective in reducing post-fire runoff and erosion in previous field studies in the region (Prats et al., 2012, 2014, 2015a), while the reduced rate had been found to be nearly as effective as the standard rate in a recent study in the hydraulic laboratory of the University of Coimbra (Prats et al., 2015b). Unlike the referred prior studies, however, the present study will also assess the impacts of mulching on two other soil threats - i.e. decline in soil organic matter and in soil biodiversity - and, ultimately, will compare the two measures in terms of their consequences for soil-based ecosystem services, using the framework being developed by RECARE (Schwilch et al. in Stolte et al., 2016). The proposed presentation will show the first results on the effects of the two mulch application rates on post-fire runoff as well as the associated losses of sediments, organic matter/C and nutrients (N, P), and on selected indicators of soil biological activity and diversity. Prats et al., 2015a (in press). LD&D (doi: 10.1002/ldr.2422) Prats et al., 2015b. FLAMMA, 6 (3), 113-116.( Prats et al., 2014. STOTEN (doi: 10.1016/j.scitotenv.2013.08.066) Prats et al., 2012. Geoderma (doi: 10.1016/j.geoderma.2012.02.009) Stolte et al., 2016. EUR 27607 (doi:10.2788/828742, online)

Managing the Increasing Water Footprint of Hydraulic Fracturing in the Bakken Play, United States.

PubMed

Scanlon, Bridget R; Reedy, Robert C; Male, Frank; Hove, Michael

2016-09-20

The water footprint of oil production, including water used for hydraulic fracturing (HF) and flowback-produced (FP) water, is increasingly important in terms of HF water sourcing and FP water management. Here, we evaluate trends in HF water use relative to supplies and FP water relative to disposal using well by well analysis in the Bakken Play. HF water use per well increased by ∼6 times from 2005-2014, totaling 24.5 × 10(9) gal (93 × 10(9) L) for ∼10 140 wells. Water supplies expanded to meet increased demand, including access of up to ∼33 × 10(9) gal/year (125 × 10(9) L/year) from Lake Sakakawea, expanding pipeline infrastructure by hundreds of miles and allowing water transfers from irrigation. The projected inventory of ∼60 000 future wells should require an additional ∼11 times more HF water. Cumulative FP water has been managed by disposal into an increasing number (277 to 479) of salt water disposal wells. FP water is projected to increase by ∼10 times during the play lifetime (∼40 years). Disposal of FP water into deeper geologic units should be considered because of reported overpressuring of parts of the Dakota Group. The long time series shows how policies have increased water supplies for HF and highlights potential issues related to FP water management.

Design of the monitoring system at the Sant'Alessio induced riverbank filtration plant (Lucca, Italy)

NASA Astrophysics Data System (ADS)

Rossetto, Rudy; Barbagli, Alessio; Borsi, Iacopo; Mazzanti, Giorgio; Picciaia, Daniele; Vienken, Thomas; Bonari, Enrico

2015-04-01

In Managed Aquifer Recharge (MAR) schemes the monitoring system, for both water quality and quantity issues, plays a key role in assuring that a groundwater recharge plant is really managed. Considering induced Riverbank Filtration (RBF) schemes, while the effect of the augmented filtration consists in an improvement of the quality and quantity of the water infiltrating the aquifer, there is in turn the risk for groundwater contamination, as surface water bodies are highly susceptible to contamination. Within the framework of the MARSOL (2014) EU FPVII-ENV-2013 project, an experimental monitoring system has been designed and will be set in place at the Sant'Alessio RBF well field (Lucca, Italy) to demonstrate the sustainability and the benefits of managing induced RBF versus the unmanaged option. The RBF scheme in Sant'Alessio (Borsi et al. 2014) allows abstraction of an overall amount of about 0,5 m3/s groundwater providing drinking water for about 300000 people of the coastal Tuscany. Water is derived by ten vertical wells set along the Serchio River embankments inducing river water filtration into a high yield (10-2m2/s transmissivity) sand and gravel aquifer. Prior to the monitoring system design, a detailed site characterization has been completed taking advantage of previous and new investigations, the latter performed by means of MOSAIC on-site investigation platform (UFZ). A monitoring network has been set in place in the well field area using existing wells. There groundwater head and the main physico-chemical parameters (temperature, pH, dissolved oxygen, electrical conductivity and redox potential) are routinely monitored. Major geochemical compounds along with a large set of emerging pollutants are analysed (in cooperation with IWW Zentrum Wasser, Germany) both in surface-water and ground-water. The experimental monitoring system (including sensors in surface- and ground-water) has been designed focusing on managing abstraction efficiency and safety at one of the ten productive wells. The groundwater monitoring system consists of a set of six piezometer clusters drilled around a reference well along the main groundwater flowpaths. At each cluster, three piezometers (screened in the penultimate meter) are set at different depths to allow multilevel monitoring and sampling. At six selected piezometers, depending on ongoing hydrogeochemical investigations, six sensors for continuous monitoring of groundwater head, temperature and electrical conductivity will be set in operation. Within the Serchio River, two monitoring stations will be set in operation in order to monitor river head, water temperature and electrical conductivity upstream and downstream the experimental plot. A multi/parameter probe for the detection of selected analytes such nitrates, and selected organics to be defined will also be set in the Serchio River water. Each sensor will constitute a node of a Wireless Sensor Network (WSN). The WSN is based on several data loggers «client» connected via radio to one server point (Gateway), transmitting to a server via GSM-GPRS. This set up, while maintaining the high quality of data transmission, will allow to reduce installation and operational costs. The main characteristic of the conceived monitoring system is that sensors have been selected so to transmit data in an open format. The sensor network prototype will allow to get a substantial sensor cost reduction compared to available commercial solutions. The ultimate goal of this complex monitoring setting will be that of defining the minimum monitoring set up to guarantee efficiency and safety of groundwater withdrawals. Acknowledgements The authors wish to acknowledge GEAL spa for technical support and granting access to the well field. The activities described in this paper are co-financed within the framework of the EU FP7-ENV-2013-WATER-INNO-DEMO MARSOL (Grant Agreement n. 619120). References Borsi, I., Mazzanti, G., Barbagli, A., Rossetto, R., 2014. The riverbank filtration plant in S. Alessio (Lucca): monitoring and modeling activity within EU the FP7 MARSOL project. Acque Sotterranee - Italian Journal of Groundwater, Vol. 3, n. 3/137 MARSOL (2014). Demonstrating Managed Aquifer Recharge as a Solution to Water Scarcity and Drought www.marsol.eu [accessed 4 January 2015

Natural and Anthropogenic Geohazards in Greater London Observed from Geological and ERS-1/2 and ENVISAT Persistent Scatterers Ground Motion Data: Results from the EC FP7-SPACE PanGeo Project

NASA Astrophysics Data System (ADS)

Cigna, Francesca; Jordan, Hannah; Bateson, Luke; McCormack, Harry; Roberts, Claire

2015-11-01

We combine geological data and ground motion estimates from satellite ERS-1/2 and ENVISAT persistent scatterer interferometry (PSI) to delineate areas of observed natural and anthropogenic geohazards in the administrative area of Greater London (United Kingdom). This analysis was performed within the framework of the EC FP7-SPACE PanGeo project, and by conforming to the interpretation and geohazard mapping methodology extensively described in the Production Manual (cf. http://www.pangeoproject.eu). We discuss the results of the generation of the PanGeo digital geohazard mapping product for Greater London, and analyse the potential of PSI, geological data and the PanGeo methodology to identify areas of observed geohazards. Based on the analysis of PSI ground motion data sets for the years 1992-2000 and 2002-2010 and geology field campaigns, we identify 25 geohazard polygons, covering a total of ~650 km2. These include not only natural processes such as compaction of deposits on the River Thames flood plain and slope instability, but also anthropogenic instability due to groundwater management and changes in the Chalk aquifer, recent engineering works such as those for the Jubilee Line Extension project and electricity tunnelling in proximity to the River Thames, and the presence of made ground. In many instances, natural and anthropogenic observed geohazards overlap, therefore indicating interaction of different processes over the same areas. In terms of ground area covered, the dominant geohazard is anthropogenic land subsidence caused by groundwater abstraction for a total of ~300 km2, followed by natural compression of River Thames sediments over ~105 km2. Observed ground motions along the satellite line-of-sight are as high as +29.5 and -25.3 mm/year, and indicate a combination of land surface processes comprising ground subsidence and uplift, as well as downslope movements. Across the areas of observed geohazards, urban land cover types from the Copernicus (formerly GMES) EEA European Urban Atlas, e.g., continuous and discontinuous urban fabric and industrial units, show the highest average velocities away from the satellite sensor, and the smallest standard deviations (~0.7-1.0 mm/year). More rural land cover types such as agricultural, semi-natural and green areas reveal the highest spatial variability (up to ~4.4 mm/year), thus suggesting greater heterogeneity of observed motion rates within these land cover types. Areas of observed motion in the PSI data for which a geological interpretation cannot be found with sufficient degree of certainty are also identified, and their possible causes discussed. Although present in Greater London, some geohazard types such as shrink-swell clays and ground dissolution are not highlighted by the interpretation of PSI annual motion rates. Reasons for absence of evidence of the latter in the PSI data are discussed, together with difficulties related to the identification of good radar scatterers in landsliding areas.

Noninvasive characterization of the Trecate (Italy) crude-oil contaminated site: links between contamination and geophysical signals.

PubMed

Cassiani, Giorgio; Binley, Andrew; Kemna, Andreas; Wehrer, Markus; Orozco, Adrian Flores; Deiana, Rita; Boaga, Jacopo; Rossi, Matteo; Dietrich, Peter; Werban, Ulrike; Zschornack, Ludwig; Godio, Alberto; JafarGandomi, Arash; Deidda, Gian Piero

2014-01-01

The characterization of contaminated sites can benefit from the supplementation of direct investigations with a set of less invasive and more extensive measurements. A combination of geophysical methods and direct push techniques for contaminated land characterization has been proposed within the EU FP7 project ModelPROBE and the affiliated project SoilCAM. In this paper, we present results of the investigations conducted at the Trecate field site (NW Italy), which was affected in 1994 by crude oil contamination. The less invasive investigations include ground-penetrating radar (GPR), electrical resistivity tomography (ERT), and electromagnetic induction (EMI) surveys, together with direct push sampling and soil electrical conductivity (EC) logs. Many of the geophysical measurements were conducted in time-lapse mode in order to separate static and dynamic signals, the latter being linked to strong seasonal changes in water table elevations. The main challenge was to extract significant geophysical signals linked to contamination from the mix of geological and hydrological signals present at the site. The most significant aspects of this characterization are: (a) the geometrical link between the distribution of contamination and the site's heterogeneity, with particular regard to the presence of less permeable layers, as evidenced by the extensive surface geophysical measurements; and (b) the link between contamination and specific geophysical signals, particularly evident from cross-hole measurements. The extensive work conducted at the Trecate site shows how a combination of direct (e.g., chemical) and indirect (e.g., geophysical) investigations can lead to a comprehensive and solid understanding of a contaminated site's mechanisms.

Monte Carlo simulations for the space radiation superconducting shield project (SR2S).

PubMed

Vuolo, M; Giraudo, M; Musenich, R; Calvelli, V; Ambroglini, F; Burger, W J; Battiston, R

2016-02-01

Astronauts on deep-space long-duration missions will be exposed for long time to galactic cosmic rays (GCR) and Solar Particle Events (SPE). The exposure to space radiation could lead to both acute and late effects in the crew members and well defined countermeasures do not exist nowadays. The simplest solution given by optimized passive shielding is not able to reduce the dose deposited by GCRs below the actual dose limits, therefore other solutions, such as active shielding employing superconducting magnetic fields, are under study. In the framework of the EU FP7 SR2S Project - Space Radiation Superconducting Shield--a toroidal magnetic system based on MgB2 superconductors has been analyzed through detailed Monte Carlo simulations using Geant4 interface GRAS. Spacecraft and magnets were modeled together with a simplified mechanical structure supporting the coils. Radiation transport through magnetic fields and materials was simulated for a deep-space mission scenario, considering for the first time the effect of secondary particles produced in the passage of space radiation through the active shielding and spacecraft structures. When modeling the structures supporting the active shielding systems and the habitat, the radiation protection efficiency of the magnetic field is severely decreasing compared to the one reported in previous studies, when only the magnetic field was modeled around the crew. This is due to the large production of secondary radiation taking place in the material surrounding the habitat. Copyright © 2016 The Committee on Space Research (COSPAR). Published by Elsevier Ltd. All rights reserved.

A model for Southern Mediterranean research institute self-assessment: a SWOT analysis-based approach to promote capacity building at Theodor Bilharz Research Institute in Cairo (Egypt).

PubMed

Ghinolfi, Davide; El Baz, Hanan G; Borgonovi, Elio; Radwan, Amr; Laurence, Ola; Sayed, Hanan A; De Simone, Paolo; Abdelwadoud, Moaz; Stefani, Alessandro; Botros, Sanaa S; Filipponi, Franco

2014-01-01

THEBERA is a project funded by the European Union (EU), as an ERA-WIDE FP7 project, aiming to strengthen the Theodor Bilharz Research Institute (TBRI) capacities. A SWOT (strength/weakness/opportunities/threats) analysis of human, structural and organisational existing resources was performed in light of an extensive analysis of liver disease research and clinical management in Egypt, for a full understanding of TBRI needs. Strength and weakness features were identified and analysed, so were actions to be implemented and targets to be accomplished, to develop a business plan gathering the required critical mass (political, scientific, industrial, social) to select investment priorities, to sacrifice non-strategic areas of research, to promote national and international connections and industrial innovations, to update diagnostics and research device technologies and clinical management processes at European levels, to implement fundraising activities, to organise and properly assess training activities for young researchers, physicians, nurses, and technicians. Research institute self assessment is a priority need for sustainable capacity building and for future build-up of a competent health care research institute. Sustainable capacity building strategies must be designed on needs assessment, involving salient requirements: clear strategy, leverage of administrative capacities, industrial support and connections, systematised training programmes and enhancement of mobility of health care staff implemented within ill-defined boundaries and continuously re-evaluated with multiple feedback loops in order to build a complex, adaptable and reliable system based on value. Copyright © 2014 Arab Journal of Gastroenterology. Published by Elsevier B.V. All rights reserved.

Sea ice proxies, marine environmental change, and human societies in Northwest Greenland over the past ca. 4500 years

NASA Astrophysics Data System (ADS)

Ribeiro, Sofia; Weckström, Kaarina; Tallberg, Petra; Risager Kjøller, Marianne; Limoges, Audrey; Massé, Guillaume; Nissen, Martin; Toudal Pedersen, Leif; Mikkelsen, Naja

2016-04-01

Greenland has been inhabited for only ca. 4500 years, but several human colonization events and cultural transitions occurred during this period. This work is part of the ICE-ARC project - Ice, Climate and Economics in the Arctic (EU FP7), aimed at understanding and quantifying the multiple stresses involved in the change in the Arctic marine environment, with particular focus on the rapid retreat and collapse of the Arctic sea ice cover. The overall goal of the project is to assess the climatic (ice, ocean, atmosphere and ecosystem), economic and social impacts of these stresses on regional and global scales. Marine sediment cores were retrieved from the Inglefield Bredning fjord system in the Qaanaaq region, Northwest Greenland, and are being analysed for various climate and environmental proxies, including biological indicators (e.g. dinoflagellate cysts, diatoms), biogeochemical elements (biogenic silica, XRF scanning), and sea-ice specific biomarkers (IP25). We will present the first data from this core material, consisting of a spatial study of sea ice and productivity proxies in 13 surface sediment samples (IP25, biogenic silica, diatoms, and dinoflagellate cysts) which will be compared with satellite-derived sea ice cover data for the Qaanaaq region/ northern Baffin Bay. This spatial study will serve as basis to reconstruct sea ice variability in the area over the past ca. 4500 years, and will be combined with historical and archaeological data in order to identify possible links between past changes in climate and sea ice conditions, and events of human migration and cultural transition in Greenland.

PERICLES: a knowledge management programme applied to solar data from International Space Station-Columbus

NASA Astrophysics Data System (ADS)

Muller, Christian; PERICLES Consortium

2017-06-01

The FP-7 (Framework Programme 7 of the European Union) PERICLES project addresses the life-cycle of large and complex data sets to cater for the evolution of context of data sets and user communities, including groups unanticipated when the data was created. Semantics of data sets are thus also expected to evolve and the project includes elements which could address the reuse of data sets at periods where the data providers and even their institutions are not available any more. This paper presents the PERICLES science case with the example of the SOLAR (SOLAR monitoring observatory) payload on International Space Station-Columbus.

Demonstrating the climate4impact portal: bridging the CMIP5 data infrastructure to impact users

NASA Astrophysics Data System (ADS)

Plieger, Maarten; Som de Cerff, Wim; Page, Christian; Hutjes, Ronald; de Jong, Fokke; Bärring, Lars; Sjökvist, Elin

2013-04-01

Together with seven other partners (CERFACS, CNRS-IPSL, SMHI, INHGA, CMCC, WUR, MF-CNRM), KNMI is involved in the FP7 project IS-ENES (http://is.enes.org), which supports the European climate modeling infrastructure, in the work package 'Bridging Climate Research Data and the Needs of the Impact Community'. The aim of this work package is to enhance the use of climate model data and to enhance the interaction with climate effect/impact communities. The portal is based on 17 impact use cases from 5 different European countries, and is evaluated by a user panel consisting of use case owners. As the climate impact community is very broad, the focus is mainly on the scientific impact community. This work has resulted in a prototype portal, the ENES portal interface for climate impact communities, that can be visited at www.climate4impact.eu. The portal is connected to all Earth System Grid Federation (ESGF) nodes containing global climate model data (GCM data) from the fifth phase of the Coupled Model Intercomparison Project (CMIP5) and later from the Coordinated Regional Climate Downscaling Experiment (CORDEX). This global network of all major climate model data centers offers services for data description, discovery and download. The climate4impact portal connects to these services and offers a user interface for searching, visualizing and downloading global climate model data and more. During the project, the content management system Drupal was used to enable partners to contribute on the documentation section. The following topics will be demonstrated: - Security: Login using OpenID for access to the ESG data nodes. The ESG works in conjunction with several external websites and systems. The climate4impact portal uses X509 based short lived credentials, generated on behalf of the user with a MyProxy service. Single Sign-on (SSO) is used to make these websites and systems work together. - Discovery: Facetted search based on e.g. variable name, model and institute using the ESG search services. A catalog browser allows for browsing through CMIP5 and other climate model data catalogues (e.g. ESSENCE, EOBS, UNIDATA). - Download: Directly from ESG nodes and other THREDDS catalogs - Visualization: Visualize any data directly using ADAGUC dynamic Web Map Services. - Transformation: Transform your data into other formats, perform basic calculations and extractions using OCG Web Processing Services The current portal is a Prototype. It is built to explore state-of-art technologies to provide improved access to climate model data. The prototype will be evaluated and is the basis for development of an operational service. The portal and services provided will be sustained and supported during the development of these operational services (2013-2016) in the second phase of the FP7 IS-ENES project, ISENES2.

Design of a testing strategy using non-animal based test methods: lessons learnt from the ACuteTox project.

PubMed

Kopp-Schneider, Annette; Prieto, Pilar; Kinsner-Ovaskainen, Agnieszka; Stanzel, Sven

2013-06-01

In the framework of toxicology, a testing strategy can be viewed as a series of steps which are taken to come to a final prediction about a characteristic of a compound under study. The testing strategy is performed as a single-step procedure, usually called a test battery, using simultaneously all information collected on different endpoints, or as tiered approach in which a decision tree is followed. Design of a testing strategy involves statistical considerations, such as the development of a statistical prediction model. During the EU FP6 ACuteTox project, several prediction models were proposed on the basis of statistical classification algorithms which we illustrate here. The final choice of testing strategies was not based on statistical considerations alone. However, without thorough statistical evaluations a testing strategy cannot be identified. We present here a number of observations made from the statistical viewpoint which relate to the development of testing strategies. The points we make were derived from problems we had to deal with during the evaluation of this large research project. A central issue during the development of a prediction model is the danger of overfitting. Procedures are presented to deal with this challenge. Copyright © 2012 Elsevier Ltd. All rights reserved.

Fetal/Placental weight ratio in term Japanese pregnancy: its difference among gender, parity, and infant growth.

PubMed

Matsuda, Yoshio; Ogawa, Masaki; Nakai, Akihito; Hayashi, Masako; Satoh, Shoji; Matsubara, Shigeki

2015-01-01

The "inappropriately heavy placenta" has been considered to be associated with various pregnancy disorders; however, data is scarce what factors affect it. To determine whether the following three affect it; (1) infant gender and mother's parity, (2) growth restriction, and (3) preeclampsia. We employed fetal/placental weight ratio (F/P). Subjects consisted of 53,650 infants and their placentas from women who vaginally delivered singleton live term infants. First, we examined whether F/P differs among the infant's gender or mother's parity. We classified the population into 4 categories according to gender and parity: male, nulliparous (n=7,431), male, multiparous (n=7,859), female, nulliparous (n=7,559), female, multiparous (n=7,800), and, compared F/P among the four groups. Next, we determined whether F/P differs in "small" or "large" for gestational age (SGA or LGA) infants, compared with appropriate for gestational age infants. Last, we determined whether preeclampsia (representative disorder of SGA) affects F/P. (1) F/P significantly differed according to infant gender and parity: female and nulliparity had significantly smaller F/P. F/P was significantly smaller in (2) SGA infants, and (3) infants from preeclamptic mothers. We for the first time showed that in Japanese term vaginally-delivered singleton population, the following three had significantly smaller F/P than controls thus had "inappropriately heavy placenta": (1) female gender and nulliparity, (2) SGA infants, and (3) infants from preeclamptic mothers. We recommend that these factors should be taken into account in evaluating placental weight. These data may also be useful for further clarifying the fetal-placental pathophysiology in these conditions.

Assessing the capability of high resolution climatic model experiments to simulate Mediterranean cyclonic tracks

NASA Astrophysics Data System (ADS)

Hatzaki, M.; Flocas, H. A.; Giannakopoulos, C.; Kostopoulou, E.; Kouroutzoglou, I.; Keay, K.; Simmonds, I.

2010-09-01

In this study, a comparison of a reanalysis driven simulation to a GCM driven simulation of a regional climate model is performed in order to assess the model's ability to capture the climatic characteristics of cyclonic tracks in the Mediterranean in the present climate. The ultimate scope of the study will be to perform a future climate projection related to cyclonic tracks in order to better understand and assess climate change in the Mediterranean. The climatology of the cyclonic tracks includes inter-monthly variations, classification of tracks according to their origin domain, dynamic and kinematic characteristics, as well as trend analysis. For this purpose, the ENEA model is employed based on PROTHEUS system composed of the RegCM atmospheric regional model and the MITgcm ocean model, coupled through the OASIS3 flux coupler. These model data became available through the EU Project CIRCE which aims to perform, for the first time, climate change projections with a realistic representation of the Mediterranean Sea. Two experiments are employed; a) the ERA402 with lateral Boundary conditions from ERA40 for the 43-year period 1958-2000, and b) the EH5OM_20C3M where the lateral boundary conditions for the atmosphere (1951-2000) are taken from the ECHAM5-MPIOM 20c3m global simulation (run3) included in the IPCC-AR4. The identification and tracking of cyclones is performed with the aid of the Melbourne University algorithm (MS algorithm), according to the Lagrangian perspective. MS algorithm characterizes a cyclone only if a vorticity maximum could be connected with a local pressure minimum. This approach is considered to be crucial, since open lows are also incorporated into the storm life-cycle, preventing possible inappropriate time series breaks, if a temporary weakening to an open-low state occurs. The model experiments verify that considerable inter-monthly variations of track density occur in the Mediterranean region, consistent with previous studies. The classification of the tracks according to their origin domain show that the vast majority originate within the examined area itself. The study of the kinematic and dynamic parameters of tracks according to their origin demonstrate that deeper cyclones follow the SW track. ACKNOWLEDGMENTS: M. Hatzaki would like to thank the Greek State Scholarships Foundation for financial support through the program of postdoctoral research. The support of EU-FP6 project CIRCE Integrated Project-Climate Change and Impact Research: the Mediterranean Environment (http://www.circeproject.eu) for climate model data provision is also greatly acknowledged.

Towards a single seismological service infrastructure in Europe

NASA Astrophysics Data System (ADS)

Spinuso, A.; Trani, L.; Frobert, L.; Van Eck, T.

2012-04-01

In the last five year services and data providers, within the seismological community in Europe, focused their efforts in migrating the way of opening their archives towards a Service Oriented Architecture (SOA). This process tries to follow pragmatically the technological trends and available solutions aiming at effectively improving all the data stewardship activities. These advancements are possible thanks to the cooperation and the follow-ups of several EC infrastructural projects that, by looking at general purpose techniques, combine their developments envisioning a multidisciplinary platform for the earth observation as the final common objective (EPOS, Earth Plate Observation System) One of the first results of this effort is the Earthquake Data Portal (http://www.seismicportal.eu), which provides a collection of tools to discover, visualize and access a variety of seismological data sets like seismic waveform, accelerometric data, earthquake catalogs and parameters. The Portal offers a cohesive distributed search environment, linking data search and access across multiple data providers through interactive web-services, map-based tools and diverse command-line clients. Our work continues under other EU FP7 projects. Here we will address initiatives in two of those projects. The NERA, (Network of European Research Infrastructures for Earthquake Risk Assessment and Mitigation) project will implement a Common Services Architecture based on OGC services APIs, in order to provide Resource-Oriented common interfaces across the data access and processing services. This will improve interoperability between tools and across projects, enabling the development of higher-level applications that can uniformly access the data and processing services of all participants. This effort will be conducted jointly with the VERCE project (Virtual Earthquake and Seismology Research Community for Europe). VERCE aims to enable seismologists to exploit the wealth of seismic data within a data-intensive computation framework, which will be tailored to the specific needs of the community. It will provide a new interoperable infrastructure, as the computational backbone laying behind the publicly available interfaces. VERCE will have to face the challenges of implementing a service oriented architecture providing an efficient layer between the Data and the Grid infrastructures, coupling HPC data analysis and HPC data modeling applications through the execution of workflows and data sharing mechanism. Online registries of interoperable worklflow components, storage of intermediate results and data provenance are those aspects that are currently under investigations to make the VERCE facilities usable from a large scale of users, data and service providers. For such purposes the adoption of a Digital Object Architecture, to create online catalogs referencing and describing semantically all these distributed resources, such as datasets, computational processes and derivative products, is seen as one of the viable solution to monitor and steer the usage of the infrastructure, increasing its efficiency and the cooperation among the community.

Costs can influence family planning decisions.

PubMed

Barnett, B

1998-01-01

This article discusses research in Cebu, Philippines, that examines the relationship between costs and income and family planning (FP) decisions. Clients weigh the costs and benefits of obtaining FP services. Costs may include the time to purchase supplies, travel to clinics, child care, and lost work time. Women should consider the costs of having more children. Family Health International's Women's Studies Project explored couple's FP decision-making. In Cebu, women play a decisive role in household expenditure decisions. 64% of women made sole decisions about children's shoes and clothing. 43% made decisions about taking children to the doctor. Women consulted husbands for larger expenditures, such as land purchases, hiring household help, and travel outside Cebu. If conflicts arose, 82% reported a mutual final decision, while 12% accepted the husband's judgment. Only 12% of women made sole decisions about FP. About 20% of the sample of women discussed FP with adult females. 25% of the women who consulted their husbands about FP made the final decision when there was conflict. Only 7% reported that the husband's decision was final. A recent follow-up study to a 1983 study finds that price is only one among many factors that affect contraceptive decision-making. Rural women in Cebu reported that the time needed to obtain contraceptives was an important factor in determining their use. A study of 64 women in rural southern India finds that contraceptive prevalence was influenced by women's autonomy rather than income. Women's and children's ages, family size, and birth order affected women's autonomy and access to money. In another related study, Pakistani women had lower fertility rates when wives' unearned income was high. An increase by 25% in unearned income among rural women decreased fertility by one child.

Immunohistochemistry of cytokeratins 7, 8, 17, 18, and 19, and GLUT-1 aids differentiation of desmoplastic malignant mesothelioma from fibrous pleuritis.

PubMed

Horiuchi, Toshikatsu; Ogata, Sho; Tominaga, Susumu; Hiroi, Sadayuki; Kawahara, Kunimitsu; Hebisawa, Akira; Irei, Isao; Ito, Ichiro; Kameya, Toru; Tsujimura, Tohru; Nakano, Takashi; Nakanishi, Kuniaki; Kawai, Toshiaki

2013-05-01

It is difficult to distinguish desmoplastic malignant mesothelioma (DMM) from fibrous pleuritis (FP). We investigated the utility of immunohistochemistry as a way of differentiating between DMM and FP. We examined 11 DMMs and 46 FPs with the aid of antibodies against 18 cytokeratin (CK) subtypes, calponin, caldesmon, desmin, and GLUT-1. The best sensitivity and specificity cut-off values in the receiver operating characteristic curves (ROC) for CKs 7, 8, 17, 18, and 19, and GLUT-1 were each above 60%. When cases with either DMM or FP were partitioned by the staining score associated with the best sensitivity and specificity cut-off values in ROC, the incidence of a positive expression for CKs 7, 8, 17, 18, and 19, and GLUT-1 was significantly higher in DMM than in FP. In conclusion, immunohistochemistry for CKs 7, 8, 17, 18, and 19, and GLUT-1 may be useful, alongside histological characteristics, for separating DMM from FP.

The ASTARTE Paleotsunami Deposits data base - a web-based reference for tsunami research around Europe

NASA Astrophysics Data System (ADS)

De Martini, Paolo Marco; Orefice, Simone; Patera, Antonio; Paris, Raphael; Terrinha, Pedro; Noiva, Joao; Hunt, James; Pantosti, Daniela

2016-04-01

EU project ASTARTE aims at developing a higher level of tsunami hazard assessment in the North East Atlantic and Mediterranean (NEAM) region by a combination of field work, experimental work, numerical modeling and technical development. The project is a cooperative work of 26 institutes from 16 countries and links together the description of past tsunamigenic events, the characterization of tsunami sources, the calculation of the impact of such events, and the development of adequate resilience strategies (www.astarte.eu). Within ASTARTE a web-based data base on Paleotsunami Deposits in the NEAM areas is being created that will be the future reference source for this kind of research in Europe. The aim is to integrate every existing scientific reference on the topic and update on new entries every six months, hosting information and detailed data that are crucial, e.g for tsunami modeling. At present 127 sites with evidence for at least one paleotsunami deposit have been collected. A relational database managed by ArcGIS for Desktop 10.3 software has been implemented to allow all partners to collaborate through a common platform for archiving and exchanging data and interpretations, such as paleotsunami type of evidence (sediment, blocks, geomorphological signature, etc), geometric characteristics (thickness, depth, etc), but also age and dating method and type of analysis supporting the tsunami interpretation. Moreover, information on the type of the site (natural or artificial exposure, exploratory trench, hand or engine core, etc), on its geomorphic setting (coastal lake, marsh, fluvial plain, offshore, etc) and on its elevation and distance from the present shoreline are provided. One of the final goals of the project is the public sharing of the archived datasets through a web-based map service that will allow to visualize, question, analyze, and interpret all datasets. The interactive map service will be hosted by ArcGIS Online and will deploy the cloud capabilities of the portal. Any interested users will be able to access the online GIS resources through any Internet browser or specific apps that run on desktop machines, smartphones, or tablets and will be able to use the analytical tools, key tasks, and workflows of the service. The research leading to these results has received funding from the European Union's Seventh Framework Programme (FP7/2007-2013) under grant agreement n° 603839 (Project ASTARTE - Assessment, Strategy and Risk Reduction for Tsunamis in Europe).

Ice nucleating particles measured during the laboratory and field intercomparisons FIN-2 and FIN-3 by the diffusion chamber FRIDGE

NASA Astrophysics Data System (ADS)

Weber, Daniel; Schrod, Jann; Curtius, Joachim; Haunold, Werner; Thomson, Erik; Bingemer, Heinz

2016-04-01

The measurement of atmospheric ice nucleating particles (INP) is still challenging. In the absence of easily applicable INP standards the intercomparison of different methods during collaborative laboratory and field workshops is a valuable tool that can shine light on the performance of individual methods for the measurement of INP [1]. FIN-2 was conducted in March 2015 at the AIDA facility in Karlsruhe as an intercomparison of mobile instruments for measuring INP [2]. FIN-3 was a field campaign at the Desert Research Institutes Storm Peak Laboratory in Colorado in September 2015 [3]. The FRankfurt Ice nucleation Deposition freezinG Experiment (FRIDGE) participated in both experiments. FRIDGE measures ice nucleating particles by electrostatic precipitation of aerosol particles onto Si-wafers in a collection unit, followed by activation, growth, and optical detection of ice crystals on the substrate in an isostatic diffusion chamber [4,5]. We will present and discuss results of our measurements of deposition/condensation INP and of immersion INP with FRIDGE during FIN-2 and FIN-3. Acknowledgements: The valuable contributions of the FIN organizers and their institutions, and of the FIN Workshop Science team are gratefully acknowledged. Our work was supported by Deutsche Forschungsgemeinschaft (DFG) under the Research Unit FOR 1525 (INUIT) and the EU FP7-ENV- 2013 BACCHUS project under Grant Agreement 603445.

The UCL NASA 3D-RPIF Imaging Centre - a status report.

NASA Astrophysics Data System (ADS)

Muller, J.-P.; Grindrod, P.

2013-09-01

The NASA RPIF (Regional Planetary Imaging Facility) network of 9 US and 8 international centres were originally set-up in 1977 to "maintain photographic and digital data as well as mission documentation and cartographic data. Each facility's general holding contains images and maps of planets and their satellites taken by solar system exploration spacecraft. These planetary image facilities are open to the public. The facilities are primarily reference centers for browsing, studying, and selecting lunar and planetary photographic and cartographic materials. Experienced staff can assist scientists, educators, students, media, and the public in ordering materials for their own use." In parallel, the NASA Planetary Data System (PDS) and ESA Planetary Science Archive (PSA) were set-up to distribute digital data initially on media such as CDROM and DVD but now entirely online. The UK NASA RPIF was the first RPIF to be established outside of the US, in 1980. In [1], the 3D-RPIF is described. Some example products derived using this equipment are illustrated here. In parallel, at MSSL a large linux cluster and associated RAID_based system has been created to act as a mirror PDS Imaging node so that huge numbers of rover imagery (from MER & MSL to begin with) and very high resolution (large size) data is available to users of the RPIF and a variety of EU-FP7 projects based at UCL.

An RFID-based luggage and passenger tracking system for airport security control applications

NASA Astrophysics Data System (ADS)

Vastianos, George E.; Kyriazanos, Dimitris M.; Kountouriotis, Vassilios I.; Thomopoulos, Stelios C. A.

2014-06-01

Market analysis studies of recent years have shown a steady and significant increase in the usage of RFID technology. Key factors for this growth were the decreased costs of passive RFIDs and their improved performance compared to the other identification technologies. Besides the benefits of RFID technologies into the supply chains, warehousing, traditional inventory and asset management applications, RFID has proven itself worth exploiting on experimental, as well as on commercial level in other sectors, such as healthcare, transport and security. In security sector, airport security is one of the biggest challenges. Airports are extremely busy public places and thus prime targets for terrorism, with aircraft, passengers, crew and airport infrastructure all subject to terrorist attacks. Inside this labyrinth of security challenges, the long range detection capability of the UHF passive RFID technology can be turned into a very important tracking tool that may outperform all the limitations of the barcode tracking inside the current airport security control chain. The Integrated Systems Lab of NCSR Demokritos has developed an RFID based Luggage and Passenger tracking system within the TASS (FP7-SEC-2010-241905) EU research project. This paper describes application scenarios of the system categorized according to the structured nature of the environment, the system architecture and presents evaluation results extracted from measurements with a group of different massive production GEN2 UHF RFID tags that are widely available in the world market.

Long Term RST Analyses of TIR Satellite Radiances in Different Geotectonic Contexts: Results and Implications for a Time-Dependent Assessment of Seismic Hazard (t-DASH)

NASA Astrophysics Data System (ADS)

Tramutoli, V.; Armandi, B.; Coviello, I.; Eleftheriou, A.; Filizzola, C.; Genzano, N.; Lacava, T.; Lisi, M.; Paciello, R.; Pergola, N.; Satriano, V.; Vallianatos, F.

2014-12-01

A large scientific documentation is to-date available about the appearance of anomalous space-time patterns of geophysical parameters measured from days to week before earthquakes occurrence. Nevertheless up to now no one measurable parameter, no one observational methodology has demonstrated to be sufficiently reliable and effective for the implementation of an operational earthquake prediction system. In this context PRE-EARTHQUAKES EU-FP7 project (www.pre-earthquakes.org), investigated to which extent the combined use of different observations/parameters together with the refinement of data analysis methods, can reduce false alarm rates and improve reliability and precision (in the space-time domain) of predictions. Among the different parameters/methodologies proposed to provide useful information in the earthquake prediction system, since 2001 a statistical approach named RST (Robust Satellite Technique) has been used to identify the space-time fluctuations of Earth's emitted Thermal Infrared (TIR) radiation observed from satellite in seismically active regions. In this paper RST-based long-term analysis of TIR satellite record collected by MSG/SEVIRI over European (Italy and Greece) and by GOES/IMAGER over American (California) regions will be presented. Its enhanced potential, when applied in the framework of time-Dependent Assessment of Seismic Hazard (t-DASH) system continuously integrating independent observations, will be moreover discussed.

The Good, the Bad and the Ugly: Remarks on data policies, their influence on system architecture, and the resilience of circumbasin countries against tsunami

NASA Astrophysics Data System (ADS)

Küppers, A. N.

2012-04-01

The performance of early warning systems directly depends on the swift provision of data from various sources. Deployed in wide areas and conceived as cross-border installations they have to serve very wide ranges of different geographical, ethno-cultural, linguistic and socio-economic groups and identities, thus bearing a high degree of intrinsic complexity besides a significant technological incoherence. In the scope of the EU FP7-projects DEWS and TRIDEC, analysis of the availability of data which is supposed to originate from seismological networks, GPS, buoys, tide gauges, ocean bottom instrumentation and satellites, was performed. The situation in the Indian Ocean basin and the Mediterranean basin both exhibit a wide range of obstacles against in time delivery of critical data. While the complete lack or poor maintenance state of sensors and the slow or hampered data transmission are the most frequent physical reasons of insufficient data generation and data flow, bureaucratic hindrances, competition between network owners, lack of standards and finally political friction between states or even nations are the overarching impediments. Based on post-disaster investigations performed in Japan and Indonesia, a set of key performance indicators for tsunami early warning systems is suggested. It is proposed to employ them as a tool for the overall improvement of data policies through high level briefings by means of supra-national initiatives.

Towards real-time risk mitigation for NPP in Switzerland: the potential role of EEW and OEF.

NASA Astrophysics Data System (ADS)

Cauzzi, Carlo; Wiemer, Stefan; Behr, Yannik; Clinton, John; Renault, Philippe; Le Guenan, Thomas; Douglas, John; Woessner, Jochen; Biro, Yesim; Caprio, Marta; Cua, Georgia

2014-05-01

Spurred by the research activities being carried out within the EC-funded project REAKT (Strategies and Tools for Real Time Earthquake Risk Reduction, FP7, contract no. 282862, 2011-2014, www.reaktproject.eu), we present herein the key elements to understanding the potential benefits of routinely using Earthquake Early Warning and Operational Earthquake Forecasting methods to mitigate the seismic risk at NPP in Switzerland. The advantages of using the aforementioned real-time risk reduction tools are critically discussed based on the limitations of the current scientific knowledge and technology, as well as on the costs associated to both system maintenance and machine- or human-triggered actions following an alert. Basic inputs to this discussion are, amongst others: a) the performances of the Swiss seismic network (http://www.seismo.ethz.ch/monitor, where SeisComP3 is used as earthquake monitoring software) and the selected EEW algorithm (the Virtual Seismologist, VS, http://www.seiscomp3.org/doc/seattle/2013.200/apps/vs.html), in terms of correct detections, false alerts, and missed events; b) the reliability of time-dependent hazard scenarios for the region of interest; c) a careful assessment of the frequency of occurrence of critical warnings based on the local and regional seismicity; d) the identification of the mitigation actions and their benefits and costs for the stakeholders.

Assessing the add value of ensemble forecast in a drought early warning

NASA Astrophysics Data System (ADS)

Calmanti, Sandro; Bosi, Lorenzo; Fernandez, Jesus; De Felice, Matteo

2015-04-01

The EU-FP7 project EUPORIAS is developing a prototype climate service to enhance the existing food security drought early warning system in Ethiopia. The Livelihoods, Early Assessment and Protection (LEAP) system is the Government of Ethiopia's national food security early warning system, established with the support of WFP and the World Bank in 2008. LEAP was designed to increase the predictability and timeliness of response to drought-related food crises in Ethiopia. It combines early warning with contingency planning and contingency funding, to allow the government, WFP and other partners to provide early assistance in anticipation of an impending catastrophes. Currently, LEAP uses satellite based rainfall estimates to monitor drought conditions and to compute needs. The main aim of the prototype is to use seasonal hindcast data to assess the added value of using ensemble climate rainfall forecasts to estimate the cost of assistance of population hit by major droughts. We outline the decision making process that is informed by the prototype climate service, and we discuss the analysis of the expected and skill of the available rainfall forecast data over Ethiopia. One critical outcome of this analysis is the strong dependence of the expected skill on the observational estimate assumed as reference. A preliminary evaluation of the full prototype products (drought indices and needs estimated) using hindcasts data will also be presented.

Underwater Multi-Vehicle Trajectory Alignment and Mapping Using Acoustic and Optical Constraints

PubMed Central

Campos, Ricard; Gracias, Nuno; Ridao, Pere

2016-01-01

Multi-robot formations are an important advance in recent robotic developments, as they allow a group of robots to merge their capacities and perform surveys in a more convenient way. With the aim of keeping the costs and acoustic communications to a minimum, cooperative navigation of multiple underwater vehicles is usually performed at the control level. In order to maintain the desired formation, individual robots just react to simple control directives extracted from range measurements or ultra-short baseline (USBL) systems. Thus, the robots are unaware of their global positioning, which presents a problem for the further processing of the collected data. The aim of this paper is two-fold. First, we present a global alignment method to correct the dead reckoning trajectories of multiple vehicles to resemble the paths followed during the mission using the acoustic messages passed between vehicles. Second, we focus on the optical mapping application of these types of formations and extend the optimization framework to allow for multi-vehicle geo-referenced optical 3D mapping using monocular cameras. The inclusion of optical constraints is not performed using the common bundle adjustment techniques, but in a form improving the computational efficiency of the resulting optimization problem and presenting a generic process to fuse optical reconstructions with navigation data. We show the performance of the proposed method on real datasets collected within the Morph EU-FP7 project. PMID:26999144

Systems Harmonization and Convergence - the GIGAS Approach

NASA Astrophysics Data System (ADS)

Marchetti, P. G.; Biancalana, A.; Coene, Y.; Uslander, T.

2009-04-01

0.1 Background The GIGAS1 Support Action promotes the coherent and interoperable development of the GMES, INSPIRE and GEOSS initiatives through their concerted adoption of standards, protocols, and open architectures. 0.2 Preparing for Coordinated Data Access The GMES Coordinated Data Access System is under design and implementation2. This objective has motivated the definition of the interoperability standards between the contributing missions. The following elements have been addressed with associated papers submitted to OGC: The EO Product Metadata has been based on the OGC Geographic Markup Language, addressing sensor characteristics for optical, radar and atmospheric products. Collection and service discovery: an ISO extension package for CSW ebRim has been proposed. Catalogue Service (CSW): an Earth Observation extension package of the CSW ebRim has been proposed. Feasibility Analysis and Order: an Order interface control document and an Earth Observation profile of the Sensor Planning Service have been proposed. Online Data Access: an Earth Observation profile of the Web Map Services (WMS) for visualization and evaluation purposes has been proposed. Identity (user) management: the objective in the long term is to allow for a single sign-on to the Coordinated Data Access system by users registered in the various Earth Observation ground segments by providing a federated identity across participating ground segments, exploiting OASIS standards. 0.3 The GIGAS proposed harmonization approach The approach proposed by GIGAS is based on three elements: Technology watch Comparative analysis Shaping of initiatives and standards This paper concentrates on the methodology for technology watch and comparative analysis. The complexity of the GIGAS scenario involving huge systems (i.e. GEOSS, INSPIRE, GMES etc.) entails the interaction with different heterogeneous partners, each with a specific competence, expertise and know-how. 0.3.1 Technology watch The methodology proposed is based on an RM-ODP based study supported by interoperability use cases and scenarios used to derive requirements. GIGAS will monitor the INSPIRE, GMES and GEOSS evolution and analyze the requirements, the standards, the services and the architecture, the models, the processes and the consensus mechanisms with the same elements of the other systems under analysis. activities in the fields of standard development that are part of the three initiatives. This task will provide the basis for how these three initiatives will strategically support consensus and efficient standards development going forward. architecture, specifications, innovative concepts and software developments of past or ongoing FP6/FP7 research topics. The use of an RM-ODP approach is selected as: most of the architectural approaches to be compared are based on RM-ODP, it supports distributed processing, it aims at fostering interoperability across heterogeneous systems, it tries to hide distribution to systems developers. However, as most of the systems to be considered have the characteristic of a loosely-coupled network of systems and services instead of a "distributed processing system based on interacting objects", the RM-ODP concepts are tailored for the GIGAS needs. The usage of RM-ODP for GIGAS Requirements and Technology Watch is two-fold: Architectural analysis: It is performed for all projects and initiatives. Its purpose is to identify possibilities but also major obstacles for interoperability. Furthermore, it identifies the major use cases to be analysed in more detail. Use Case Implementation Analysis: It is used to describe how selected use cases of the projects and initiatives are implemented in the different architectures. Its purpose is to identify technological gaps and concrete problems of interoperability. It is performed only for selected use cases. The output of the Technology Watch is an RM-ODP based report containing parallel analysis on the same aspects on the three initiatives integrated by analysis of relevant FP6-FP7 projects and standardization activities. 0.3.2 Comparative Analysis Based on the outcomes of the previous monitoring tasks, GIGAS undertakes a comparative analysis on solutions, requirements, architecture, models, processes and consensus mechanisms used by INSPIRE, GMES and GEOSS, taking into account the inputs from the monitoring of FP6/FP7 research projects and the ongoing standardization activities. Initiative Contact Points will insure that the overall policy framework and schedules for each of the three initiatives will be factored in. The result of the Comparative Analysis includes: A list of recommendations to GEOSS, INSPIRE and GMES to be expanded and processed in depth in the following shaping phase The identification of technological gaps to be explored in the following shaping phase. Guidelines and objectives for the architectural approach within GIGAS Analysis on the schedules of the three initiatives and on the FP6/FP7 programs and standardization activities, with identification of key milestones or intervention points.

Interdisciplinary assessment of sea-level rise and climate change impacts on the lower Nile delta, Egypt.

PubMed

Sušnik, Janez; Vamvakeridou-Lyroudia, Lydia S; Baumert, Niklas; Kloos, Julia; Renaud, Fabrice G; La Jeunesse, Isabelle; Mabrouk, Badr; Savić, Dragan A; Kapelan, Zoran; Ludwig, Ralf; Fischer, Georg; Roson, Roberto; Zografos, Christos

2015-01-15

CLImate-induced changes on WAter and SECurity (CLIWASEC) was a cluster of three complementary EC-FP7 projects assessing climate-change impacts throughout the Mediterranean on: hydrological cycles (CLIMB - CLimate-Induced changes on the hydrology of Mediterranean Basins); water security (WASSERMed - Water Availability and Security in Southern EuRope and the Mediterranean) and human security connected with possible hydro-climatic conflicts (CLICO - CLImate change hydro-COnflicts and human security). The Nile delta case study was common between the projects. CLIWASEC created an integrated forum for modelling and monitoring to understand potential impacts across sectors. This paper summarises key results from an integrated assessment of potential challenges to water-related security issues, focusing on expected sea-level rise impacts by the middle of the century. We use this common focus to illustrate the added value of project clustering. CLIWASEC pursued multidisciplinary research by adopting a single research objective: sea-level rise related water security threats, resulting in a more holistic view of problems and potential solutions. In fragmenting research, policy-makers can fail to understand how multiple issues can materialize from one driver. By combining efforts, an integrated assessment of water security threats in the lower Nile is formulated, offering policy-makers a clearer picture of inter-related issues to society and environment. The main issues identified by each project (land subsidence, saline intrusion - CLIMB; water supply overexploitation, land loss - WASSERMed; employment and housing security - CLICO), are in fact related. Water overexploitation is exacerbating land subsidence and saline intrusion, impacting on employment and placing additional pressure on remaining agricultural land and the underdeveloped housing market. All these have wider implications for regional development. This richer understanding could be critical in making better policy decisions when attempting to mitigate climate and social change impacts. The CLIWASEC clustering offers an encouraging path for the new European Commission Horizon 2020 programme to follow. Copyright © 2014 Elsevier B.V. All rights reserved.

Volcanic Supersites as cross-disciplinary laboratories

NASA Astrophysics Data System (ADS)

Provenzale, Antonello; Beierkuhnlein, Carl; Giamberini, Mariasilvia; Pennisi, Maddalena; Puglisi, Giuseppe

2017-04-01

Volcanic Supersites, defined in the frame of the GEO-GSNL Initiative, are usually considered mainly for their geohazard and geological characteristics. However, volcanoes are extremely challenging areas from many other points of view, including environmental and climatic properties, ecosystems, hydrology, soil properties and biogeochemical cycling. Possibly, volcanoes are closer to early Earth conditions than most other types of environment. During FP7, EC effectively fostered the implementation of the European volcano Supersites (Mt. Etna, Campi Flegrei/Vesuvius and Iceland) through the MED-SUV and FUTUREVOLC projects. Currently, the large H2020 project ECOPOTENTIAL (2015-2019, 47 partners, http://www.ecopotential-project.eu/) contributes to GEO/GEOSS and to the GEO ECO Initiative, and it is devoted to making best use of remote sensing and in situ data to improve future ecosystem benefits, focusing on a network of Protected Areas of international relevance. In ECOPOTENTIAL, remote sensing and in situ data are collected, processed and used for a better understanding of the ecosystem dynamics, analysing and modelling the effects of global changes on ecosystem functions and services, over an array of different ecosystem types, including mountain, marine, coastal, arid and semi-arid ecosystems, and also areas of volcanic origin such as the Canary and La Reunion Islands. Here, we propose to extend the network of the ECOPOTENTIAL project to include active Volcanic Supersites, such as Mount Etna and other volcanic Protected Areas, and we discuss how they can be included in the framework of the ECOPOTENTIAL workflow. A coordinated and cross-disciplinary set of studies at these sites should include geological, biological, ecological, biogeochemical, climatic and biogeographical aspects, as well as their relationship with the antropogenic impact on the environment, and aim at the global analysis of the volcanic Earth Critical Zone - namely, the upper layer of the Earth surface between the top of the vegetation and the rock matrix in active volcanic areas and Volcanic Supersites.

The Ophidia framework: toward cloud-based data analytics for climate change

NASA Astrophysics Data System (ADS)

Fiore, Sandro; D'Anca, Alessandro; Elia, Donatello; Mancini, Marco; Mariello, Andrea; Mirto, Maria; Palazzo, Cosimo; Aloisio, Giovanni

2015-04-01

The Ophidia project is a research effort on big data analytics facing scientific data analysis challenges in the climate change domain. It provides parallel (server-side) data analysis, an internal storage model and a hierarchical data organization to manage large amount of multidimensional scientific data. The Ophidia analytics platform provides several MPI-based parallel operators to manipulate large datasets (data cubes) and array-based primitives to perform data analysis on large arrays of scientific data. The most relevant data analytics use cases implemented in national and international projects target fire danger prevention (OFIDIA), interactions between climate change and biodiversity (EUBrazilCC), climate indicators and remote data analysis (CLIP-C), sea situational awareness (TESSA), large scale data analytics on CMIP5 data in NetCDF format, Climate and Forecast (CF) convention compliant (ExArch). Two use cases regarding the EU FP7 EUBrazil Cloud Connect and the INTERREG OFIDIA projects will be presented during the talk. In the former case (EUBrazilCC) the Ophidia framework is being extended to integrate scalable VM-based solutions for the management of large volumes of scientific data (both climate and satellite data) in a cloud-based environment to study how climate change affects biodiversity. In the latter one (OFIDIA) the data analytics framework is being exploited to provide operational support regarding processing chains devoted to fire danger prevention. To tackle the project challenges, data analytics workflows consisting of about 130 operators perform, among the others, parallel data analysis, metadata management, virtual file system tasks, maps generation, rolling of datasets, import/export of datasets in NetCDF format. Finally, the entire Ophidia software stack has been deployed at CMCC on 24-nodes (16-cores/node) of the Athena HPC cluster. Moreover, a cloud-based release tested with OpenNebula is also available and running in the private cloud infrastructure of the CMCC Supercomputing Centre.

Development of a Timepix based detector for the NanoXCT project

NASA Astrophysics Data System (ADS)

Nachtrab, F.; Hofmann, T.; Speier, C.; Lučić, J.; Firsching, M.; Uhlmann, N.; Takman, P.; Heinzl, C.; Holmberg, A.; Krumm, M.; Sauerwein, C.

2015-11-01

The NanoXCT EU FP7 project [1] aims at developing a laboratory, i.e. bench top sized X-ray nano-CT system with a large field-of-view (FOV) for non-destructive testing needs in the micro- and nano-technology sector. The targeted voxel size is 50 nm at 0.175 mm FOV, the maximum FOV is 1 mm at 285 nm voxel size. Within the project a suitable X-ray source, detector and manipulation system have been developed. The system concept [2] omits the use of X-ray optics, to be able to provide a large FOV of up to 1 mm and to preserve the flexibility of state-of-the-art micro-CT systems. The targeted resolution will be reached via direct geometric magnification made possible by the development of a specialized high-flux nano-focus transmission X-ray tube. The end-user's demand for elemental analysis will be covered by energy-resolved measurement techniques, in particular a K-edge imaging method. Timepix [3] modules were chosen as the basis for the detector system, since a photon counting detector is advantageous for the long exposure times that come with very small focal spot sizes. Additional advantages are the small pixel size and adjustable energy threshold. To fulfill the requirements on field-of-view, a detector width 0> 300 pixels was needed. The NanoXCT detector consists of four Hexa modules with 500 μm silicon sensors supplied by X-ray Imaging Europe. An adapter board was developed to connect all four modules to one Fitpix3 readout. The final detector has an active area of 3072 × 512 pixels or approximately 17 × 3 cm2.In this contribution we present the development of the Timepix based NanoXCT detector, it's application in the NanoXCT project for CT and material specific measurements and the current status of results.

FP-180 Water Motor AFFF Proportioner First Article Procedure and Evaluation

DTIC Science & Technology

1989-07-20

concentrates. The first fluorocarbon-based Aqueous Film Forming Foam ( AFFF ) concentrate fully suitable for use with ocean water was FC -195, which had a...Fil E W Y. . Naval Research Laboratory Washington, DC 20375-500 NRL Memorandum Report 6507 FP-180 Water Motor AFFF Proportioner First Article...NUMBERS PROGRAM :PROJECT TASK WORK UNIT ELEMENT NO NO NO ACCESSION NO 11 TITLE (Include Security Classification) FP-180 Water Motor AFFF Proportioner

ARISTOTLE (All Risk Integrated System TOward The hoListic Early-warning): a multi-hazard expert advice system for the EU disaster response

NASA Astrophysics Data System (ADS)

Michelini, A.; Wotawa, G.; Arnold-Arias, D.

2017-12-01

ARISTOTLE (http://aristotle.ingv.it/) is a Pilot Project funded by the DG ECHO (EU Humanitarian Aid and Civil Protection) that provides expert scientific advice on natural disasters around the world that may cause a country to seek international help to the EU's Emergency Response Coordination Centre (ERCC) and, consequently, to the Union Civil Protection Mechanism Participating States. The EU is committed to providing disaster response in a timely and efficient manner and to ensure European assistance meets the real needs in the population affected, whether in Europe or beyond. When a disaster strikes, every minute counts for saving lives and rapid, coordinated and pre-planned response is essential. The ARISTOTLE consortium includes 15 partner institutions (11 from EU Countries; 2 from non-EU countries and 2 European organizations) operating in the Meteorological and Geophysical domains. The project coordination is shared among INGV and ZAMG for the geophysical and meteorological communities, respectively. ARISTOTLE harnesses operational expertise from across Europe to form a multi-hazard perspective on natural disasters related to volcanoes, earthquake (and resulting tsunami), severe weather and flooding. Each Hazard Group brings together experts from the particular hazard domain to deliver a `collective analysis' which is then fed into the partnership multi-hazard discussions. Primary target of the pilot project has been the prototyping and the implementation of a scalable system (in terms of number of partners and hazards) capable of providing to ERCC the sought advice. To this end, the activities of the project have been focusing on the establishment of a "Multi-Hazard Operational Board" that is assigned the 24*7 operational duty regulated by a "Standard Operating Protocol" and the implementation of a dedicated IT platform to assembly the resulting reports. The project has reached the point where the routine and emergency advice services are being provided and will continue until the end of the project in January 2018. The presentation will illustrate the different modes of operation envisaged and the status and the solutions found by the project consortium to respond to the ERCC requirements.

Opportunities for the Mashup of Heterogenous Data Server via Semantic Web Technology

NASA Astrophysics Data System (ADS)

Ritschel, Bernd; Seelus, Christoph; Neher, Günther; Iyemori, Toshihiko; Koyama, Yukinobu; Yatagai, Akiyo; Murayama, Yasuhiro; King, Todd; Hughes, John; Fung, Shing; Galkin, Ivan; Hapgood, Michael; Belehaki, Anna

2015-04-01

Opportunities for the Mashup of Heterogenous Data Server via Semantic Web Technology European Union ESPAS, Japanese IUGONET and GFZ ISDC data server are developed for the ingestion, archiving and distributing of geo and space science domain data. Main parts of the data -managed by the mentioned data server- are related to near earth-space and geomagnetic field data. A smart mashup of the data server would allow a seamless browse and access to data and related context information. However the achievement of a high level of interoperability is a challenge because the data server are based on different data models and software frameworks. This paper is focused on the latest experiments and results for the mashup of the data server using the semantic Web approach. Besides the mashup of domain and terminological ontologies, especially the options to connect data managed by relational databases using D2R server and SPARQL technology will be addressed. A successful realization of the data server mashup will not only have a positive impact to the data users of the specific scientific domain but also to related projects, such as e.g. the development of a new interoperable version of NASA's Planetary Data System (PDS) or ICUS's World Data System alliance. ESPAS data server: https://www.espas-fp7.eu/portal/ IUGONET data server: http://search.iugonet.org/iugonet/ GFZ ISDC data server (semantic Web based prototype): http://rz-vm30.gfz-potsdam.de/drupal-7.9/ NASA PDS: http://pds.nasa.gov ICSU-WDS: https://www.icsu-wds.org

SCHeMA open and modular in situ sensing solution

NASA Astrophysics Data System (ADS)

Tercier-Waeber, Marie Louise; Novellino, Antonio

2017-04-01

Marine environments are highly vulnerable and influenced by a wide diversity of anthropogenic and natural substances and organisms that may have adverse effects on the ecosystem equilibrium, on living resources and, ultimately, on human health. Identification of relevant types of hazards at the appropriate temporal and spatial scale is crucial to detect their sources and origin, to understand the processes governing their magnitude and distribution, and to ultimately evaluate and manage their risks and consequences preventing economic losses. This can be addressed only by the development of innovative, compact, rugged, automated, sensor networks allowing long-term monitoring. Development of such tools is a challenging task as it requires many analytical and technical innovations. The FP7-OCEAN 2013-SCHeMA project aims to contribute to meet this challenge by providing an open and modular sensing solution for autonomous in situ high resolution mapping of a range of anthropogenic and natural chemical compounds (trace metals, nutrients, anthropogenic organic compounds, toxic algae species and toxins, species relevant to the carbon cycle). To achieve this, SCHeMA activities focus on the development of : 1) an array of miniature sensor probes taking advantage of various innovative solutions, namely: (polymer-based) gel-integrated sensors; solid state ion-selective membrane sensors coupled to an on-line desalination module; mid-infrared optical sensors; optochemical multichannel devices; enOcean technology; 2) dedicated hardware, firmware and software components allowing their plug-and-play integration, localization as well as wireless bidirectional communication via advanced OGC-SWE wired/wireless dedicated interfaces; 3) a web-based front-end system compatible with EU standard requirements and principles (INSPIRE, GEO/GEOSS) and configured to insure easy interoperability with national, regional and local marine observation systems. This lecture will present examples of innovative approaches and devices successfully developed and currently explored. Potentiality of the SCHeMA individual probes and integrated system to provide new type of high-resolution environmental data will be illustrated by examples of field application in selected coastal areas. www.schema-ocean.eu

RiskChanges Spatial Decision Support system for the analysis of changing multi-hazard risk

NASA Astrophysics Data System (ADS)

van Westen, Cees; Zhang, Kaixi; Bakker, Wim; Andrejchenko, Vera; Berlin, Julian; Olyazadeh, Roya; Cristal, Irina

2015-04-01

Within the framework of the EU FP7 Marie Curie Project CHANGES and the EU FP7 Copernicus project INCREO a spatial decision support system was developed with the aim to analyse the effect of risk reduction planning alternatives on reducing the risk now and in the future, and support decision makers in selecting the best alternatives. Central to the SDSS are the stakeholders. The envisaged users of the system are organizations involved in planning of risk reduction measures, and that have staff capable of visualizing and analyzing spatial data at a municipal scale. The SDSS should be able to function in different countries with different legal frameworks and with organizations with different mandates. These could be subdivided into Civil protection organization with the mandate to design disaster response plans, Expert organizations with the mandate to design structural risk reduction measures (e.g. dams, dikes, check-dams etc), and planning organizations with the mandate to make land development plans. The SDSS can be used in different ways: analyzing the current level of risk, analyzing the best alternatives for risk reduction, the evaluation of the consequences of possible future scenarios to the risk levels, and the evaluation how different risk reduction alternatives will lead to risk reduction under different future scenarios. The SDSS is developed based on open source software and following open standards, for code as well as for data formats and service interfaces. Code development was based upon open source software as well. The architecture of the system is modular. The various parts of the system are loosely coupled, extensible, using standards for interoperability, flexible and web-based. The Spatial Decision Support System is composed of a number of integrated components. The Risk Assessment component allows to carry out spatial risk analysis, with different degrees of complexity, ranging from simple exposure (overlay of hazard and assets maps) to quantitative analysis (using different hazard types, temporal scenarios and vulnerability curves) resulting into risk curves. The platform does not include a component to calculate hazard maps, and existing hazard maps are used as input data for the risk component. The second component of the SDSS is a risk reduction planning component, which forms the core of the platform. This component includes the definition of risk reduction alternatives (related to disaster response planning, risk reduction measures and spatial planning) and links back to the risk assessment module to calculate the new level of risk if the measure is implemented, and a cost-benefit (or cost-effectiveness/ Spatial Multi Criteria Evaluation) component to compare the alternatives and make decision on the optimal one. The third component of the SDSS is a temporal scenario component, which allows to define future scenarios in terms of climate change, land use change and population change, and the time periods for which these scenarios will be made. The component doesn't generate these scenarios but uses input maps for the effect of the scenarios on the hazard and assets maps. The last component is a communication and visualization component, which can compare scenarios and alternatives, not only in the form of maps, but also in other forms (risk curves, tables, graphs)

Human herpesvirus-6 and -7 DNA in cerebrospinal fluid of facial palsy patients.

PubMed

Kanerva, Mervi; Jääskeläinen, Anne J; Suvela, Minna; Piiparinen, Heli; Vaheri, Antti; Pitkäranta, Anne

2008-04-01

Finding human herpesvirus (HHV)-7 and dual HHV-6A and -6B DNA in cerebrospinal fluid (CSF) of two facial palsy (FP) patients is intriguing but does not allow etiologic conclusions as such. HHV-6 or -7 DNA was revealed in 10% of the CSF samples tested from 70 immunocompetent adolescents and adults; a highly unusual result. How these findings are associated with the diseases they accompany remains to be defined. To determine whether herpes simplex virus (HSV)-1 and -2, varicella-zoster virus (VZV), HHV-6A, -6B, and -7, Epstein-Barr virus (EBV), and cytomegalovirus (CMV) DNA could be found in CSF of FP patients or controls. In all, 33 peripheral FP patients (26 idiopathic, 5 with herpesvirus infection, 1 puerperal, 1 Melkersson-Rosenthal syndrome) (34 CSF samples) and 36 controls (16 nonidiopathic FP, 7 hearing loss, 6 vertigo, 5 headache, 2 other) previously tested for HSV-1, VZV, and HHV-6 DNA by polymerase chain reaction (PCR) were tested with highly sensitive multiplex-PCR and an oligonucleotide microarray method. One FP patient had HHV-7 DNA and another had HHV-6A and -6B DNA simultaneously. In the control group, one HHV-7, one HHV-6A, and three HHV-6B DNA-positive specimens were found.

Nutrition -- a key issue for Africa. PANFRICO IV notes importance of strengthening nutrition activities to assist FP promotion.

PubMed

1993-12-01

Malnutrition is a major concern in African countries. The incorporation of nutrition education into maternal-child health services has a direct effect on child survival and the promotion of family planning (FP). The 4th Regional Workshop on the integrated Project (PANFRICO IV) was held in Banjul, The Gambia, from September 27 through October 1, 1993, and focused on the role of nutrition in promoting the integrated project on FP, nutrition, and parasite control (IP). PANFRICO was supported by UNFPA and IPPF, and was attended by 50 participants from 15 countries, some of them IP-implementing countries such as Ethiopia, The Gambia, Ghana, Tanzania, and Zambia. Officials of UNFPA, IPPF, and JOICFP also attended the meeting, as well as two representatives of the Japan International Cooperation Agency. IPPF has supported IP since 1974 because of IP's commitment to community participation. This forum allowed participants to discuss how nutrition could be incorporated into the IP for increased acceptance of FP. Recommendations called for a stronger nutritional component in IP without losing sight of FP promotion as the main focus. The participants stressed that the improvement of the nutrition component requires government commitment, policy, analysis of the nutritional situation in planning for action, community participation (of men in particular) in implementation, intersectoral coordination of nutrition and FP strategies, and nutrition education.

H2020 EU Research & Innovation Program Boost the Transfer of Technological Breakthroughs, Enable New Solutions for Personalised Health and Impact the Industry and Healthcare Systems.

PubMed

Smit, Paul H; Lymberis, Andreas

2015-01-01

Our Healthcare systems worldwide are facing grand challenges that can be addressed by intelligent, miniaturized and interconnected devices. Many of today's pharmaceutical drugs create bigger problems than solutions, as drugs help only 40% of the patients and kill, in the USA alone, over 100,000 people per year. The widespread use of antibiotics has led to new strands of bacteria that defy all known antibiotics and kill well over 100,000 people yearly in the world. Outbreaks of infections by new viruses and anti-resistant bacteria are expected with even more grave consequences. The quality of food around the world is steadily deteriorating, as the soils are becoming depleted of essential nutrients and contain increasing amounts of pesticides, herbicides and fungicides. Our environment is burdened with 2.5 billion tonnes of chemicals per year that accumulate in the soil, groundwater, rivers and seas, and eventually end up in our food and our drinking water. As a consequence, there is a strong increase in the incidence of diseases hardly known fifty years ago. In parallel, an increasing number of people are taking the responsibility for their health and well-being in their own hands and are looking for mobile and in-obtrusive ways to objectively monitor their health status. The development of intelligent, miniaturized systems, by the heterogeneous integration of technologies such as micro- and nano-electronics, photonics, biotechnology, materials and information & communication, addresses these issues and has received intensive public support in the EU over the past two decades in the FP6 and FP7 programs. Proven concepts and functional prototypes exist with the potential to create new opportunities to improve our healthcare systems, in particular personalized or precision medicine. These device concepts offer unique abilities to sense, detect, analyze, communicate, respond, and monitor phenomena from the macro (e.g. body, tissues) to the nano scale (e.g. molecules, genes) on the spot, with short response times. For the majority of the projects, the planning for the next phase of prototype validation, through product design, supply chain setup, user targeting, clinical validation and commercial roll-out is now taking full attention. However, significant hurdles exist in the successful translation of the new technology to new products. As these technologies are new-to-the-world the resulting products carry a high risk, often necessitating the creation of new companies. Therefore the EU has developed the Horizon 2020 program as a framework for technology development and new business creation. Horizon 2020 is focusing on support for technology transfer, and on building ecosystems and value chains to ensure shorter times-to-market, thus enabling a higher impact of knowledge-based technologies. This paper will argue the necessity of developing these new class of devices, discuss its state-of-the-art, and the challenges for the implementation of Horizon 2020 and the new opportunities in intelligent miniaturized systems for pHealth.

Finite-temperature lattice dynamics and superionic transition in ceria from first principles

NASA Astrophysics Data System (ADS)

Klarbring, Johan; Skorodumova, Natalia V.; Simak, Sergei I.

2018-03-01

Ab initio molecular dynamics (AIMD) in combination with the temperature dependent effective potential (TDEP) method has been used to go beyond the quasiharmonic approximation and study the lattice dynamics in ceria, CeO2, at finite temperature. The results indicate that the previously proposed connection between the B1 u phonon mode turning imaginary and the transition to the superionic phase in fluorite structured materials is an artifact of the failure of the quasiharmonic approximation in describing the lattice dynamics at elevated temperatures. We instead show that, in the TDEP picture, a phonon mode coupling to the Eu mode prevents the B1 u mode from becoming imaginary. We directly observe the superionic transition at high temperatures in our AIMD simulations and find that it is initiated by the formation of oxygen Frenkel pairs (FP). These FP are found to form in a collective process involving simultaneous motion of two oxygen ions.

Borderless Geospatial Web (bolegweb)

NASA Astrophysics Data System (ADS)

Cetl, V.; Kliment, T.; Kliment, M.

2016-06-01

The effective access and use of geospatial information (GI) resources acquires a critical value of importance in modern knowledge based society. Standard web services defined by Open Geospatial Consortium (OGC) are frequently used within the implementations of spatial data infrastructures (SDIs) to facilitate discovery and use of geospatial data. This data is stored in databases located in a layer, called the invisible web, thus are ignored by search engines. SDI uses a catalogue (discovery) service for the web as a gateway to the GI world through the metadata defined by ISO standards, which are structurally diverse to OGC metadata. Therefore, a crosswalk needs to be implemented to bridge the OGC resources discovered on mainstream web with those documented by metadata in an SDI to enrich its information extent. A public global wide and user friendly portal of OGC resources available on the web ensures and enhances the use of GI within a multidisciplinary context and bridges the geospatial web from the end-user perspective, thus opens its borders to everybody. Project "Crosswalking the layers of geospatial information resources to enable a borderless geospatial web" with the acronym BOLEGWEB is ongoing as a postdoctoral research project at the Faculty of Geodesy, University of Zagreb in Croatia (http://bolegweb.geof.unizg.hr/). The research leading to the results of the project has received funding from the European Union Seventh Framework Programme (FP7 2007-2013) under Marie Curie FP7-PEOPLE-2011-COFUND. The project started in the November 2014 and is planned to be finished by the end of 2016. This paper provides an overview of the project, research questions and methodology, so far achieved results and future steps.

Kristeller maneuvers or fundal pressure and maternal/neonatal morbidity: obstetric and judicial literature review.

PubMed

Malvasi, Antonio; Zaami, Simona; Tinelli, Andrea; Trojano, Giuseppe; Montanari Vergallo, Gianluca; Marinelli, Enrico

2018-02-21

A significant amount of data concerning maternal-fetal damage arising from the exertion of Kristeller maneuvers (KMs) or fundal pressure (FP) go unreleased due to medicolegal implications. For this reason, the paper gathers information as to the real magnitude of litigation related to FP-induced damages and injuries. The authors have undertaken a research in order to include general search engines (PubMed-Medline, Cochrane, Embase, Google, GyneWeb) and legal databases (De Jure, Italian database of jurisprudence daily update; Westlaw, Thomson Reuters, American ruling database and Bailii, UK Court Ruling Database). Results confirm said phenomenon to be more wide ranging than it appears through official channels. Several courts of law, both in the United States of America (USA) and in European Union (EU) Member States as well, have ruled against the use of the maneuver itself, assuming a stance conducive to a presumption of guilt against those doctors and healthcare providers who resorted to KMs or FP during deliveries. Given how rife FP is in mainstream obstetric practice, it is as if there were a wide gap between obstetric real-life and what official jurisprudence and healthcare institutions-sanctioned official practices are. The authors think that it would be desirable to draft specifically targeted guidelines or recommendations on maneuvers during vaginal delivery, in which to point out exactly what kinds of maneuvering techniques are to be absolutely banned and what maneuvers are to be allowed, and under what conditions their application can be considered appropriate.

A Geo-Distributed System Architecture for Different Domains

NASA Astrophysics Data System (ADS)

Moßgraber, Jürgen; Middleton, Stuart; Tao, Ran

2013-04-01

The presentation will describe work on the system-of-systems (SoS) architecture that is being developed in the EU FP7 project TRIDEC on "Collaborative, Complex and Critical Decision-Support in Evolving Crises". In this project we deal with two use-cases: Natural Crisis Management (e.g. Tsunami Early Warning) and Industrial Subsurface Development (e.g. drilling for oil). These use-cases seem to be quite different at first sight but share a lot of similarities, like managing and looking up available sensors, extracting data from them and annotate it semantically, intelligently manage the data (big data problem), run mathematical analysis algorithms on the data and finally provide decision support on this basis. The main challenge was to create a generic architecture which fits both use-cases. The requirements to the architecture are manifold and the whole spectrum of a modern, geo-distributed and collaborative system comes into play. Obviously, one cannot expect to tackle these challenges adequately with a monolithic system or with a single technology. Therefore, a system architecture providing the blueprints to implement the system-of-systems approach has to combine multiple technologies and architectural styles. The most important architectural challenges we needed to address are 1. Build a scalable communication layer for a System-of-sytems 2. Build a resilient communication layer for a System-of-sytems 3. Efficiently publish large volumes of semantically rich sensor data 4. Scalable and high performance storage of large distributed datasets 5. Handling federated multi-domain heterogeneous data 6. Discovery of resources in a geo-distributed SoS 7. Coordination of work between geo-distributed systems The design decisions made for each of them will be presented. These developed concepts are also applicable to the requirements of the Future Internet (FI) and Internet of Things (IoT) which will provide services like smart grids, smart metering, logistics and environmental monitoring.

ACFA 2020 - An FP7 project on active control of flexible fuel efficient aircraft configurations

NASA Astrophysics Data System (ADS)

Maier, R.

2013-12-01

This paper gives an overview about the project ACFA 2020 which is funded by the European Commission within the 7th framework program. The acronym ACFA 2020 stands for Active Control for Flexible Aircraft 2020. The project is dealing with the design of highly fuel efficient aircraft configurations and, in particular, on innovative active control concepts with the goal to reduce loads and structural weight. Major focus lays on blended wing body (BWB) aircraft. Blended wing body type aircraft configurations are seen as the most promising future concept to fulfill the so-called ACARE (Advisory Council for Aeronautics Research in Europe) vision 2020 goals in regards to reduce fuel consumption and external noise. The paper discusses in some detail the overall goals and how they are addressed in the workplan. Furthermore, the major achievements of the project are outlined and a short outlook on the remaining work is given.

Hillary Clinton visits Pathfinder projects in Brazil.

PubMed

1996-01-01

In October 1995, US First Lady Hillary Clinton visited a maternity hospital in Salvador, Brazil, in which a family planning (FP)/reproductive health program has been administered by Pathfinder International since 1981 with funding from USAID. During her tour of the facility, Clinton learned about the high degree of unmet need for FP in the region which results from a lack of sufficient resources to meet demand. Clinton, in turn, praised the state of Bahia for its emphasis on FP in low-income areas.

Damage assessment of bridge infrastructure subjected to flood-related hazards

NASA Astrophysics Data System (ADS)

Michalis, Panagiotis; Cahill, Paul; Bekić, Damir; Kerin, Igor; Pakrashi, Vikram; Lapthorne, John; Morais, João Gonçalo Martins Paulo; McKeogh, Eamon

2017-04-01

Transportation assets represent a critical component of society's infrastructure systems. Flood-related hazards are considered one of the main climate change impacts on highway and railway infrastructure, threatening the security and functionality of transportation systems. Of such hazards, flood-induced scour is a primarily cause of bridge collapses worldwide and one of the most complex and challenging water flow and erosion phenomena, leading to structural instability and ultimately catastrophic failures. Evaluation of scour risk under severe flood events is a particularly challenging issue considering that depth of foundations is very difficult to evaluate in water environment. The continual inspection, assessment and maintenance of bridges and other hydraulic structures under extreme flood events requires a multidisciplinary approach, including knowledge and expertise of hydraulics, hydrology, structural engineering, geotechnics and infrastructure management. The large number of bridges under a single management unit also highlights the need for efficient management, information sharing and self-informing systems to provide reliable, cost-effective flood and scour risk management. The "Intelligent Bridge Assessment Maintenance and Management System" (BRIDGE SMS) is an EU/FP7 funded project which aims to couple state-of-the art scientific expertise in multidisciplinary engineering sectors with industrial knowledge in infrastructure management. This involves the application of integrated low-cost structural health monitoring systems to provide real-time information towards the development of an intelligent decision support tool and a web-based platform to assess and efficiently manage bridge assets. This study documents the technological experience and presents results obtained from the application of sensing systems focusing on the damage assessment of water-hazards at bridges over watercourses in Ireland. The applied instrumentation is interfaced with an open-source platform that can offer a more economical remote monitoring solution. The results presented in this investigation provide an important guide for a multidisciplinary approach to bridge monitoring and can be used as a benchmark for the field application of cost-effective and robust sensing methods. This will deliver key information regarding the impact of water-related hazards at bridge structures through an integrated structural health monitoring and management system. Acknowledgement: The authors wish to acknowledge the financial support of the European Commission, through the Marie Curie action Industry-Academia Partnership and Pathways Network BRIDGE SMS (Intelligent Bridge Assessment Maintenance and Management System) - FP7-People-2013-IAPP- 612517.

PRo3D®: A Tool for High Resolution Rendering and Geological Analysis of Martian Rover-Derived Digital Outcrop Models.

NASA Astrophysics Data System (ADS)

Gupta, S.; Barnes, R.; Ortner, T.; Huber, B.; Paar, G.; Muller, J. P.; Giordano, M.; Willner, K.; Traxler, C.; Juhart, K.; Fritz, L.; Hesina, G.; Tasdelen, E.

2015-12-01

NASA's Mars Exploration Rovers (MER) and Mars Science Laboratory Curiosity Rover (MSL) are proxies for field geologists on Mars, taking high resolution imagery of rock formations and landscapes which is analysed in detail on Earth. Panoramic digital cameras (PanCam on MER and MastCam on MSL) are used for characterising the geology of rock outcrops along rover traverses. A key focus is on sedimentary rocks that have the potential to contain evidence for ancient life on Mars. Clues to determine ancient sedimentary environments are preserved in layer geometries, sedimentary structures and grain size distribution. The panoramic camera systems take stereo images which are co-registered to create 3D point clouds of rock outcrops to be quantitatively analysed much like geologists would do on Earth. The EU FP7 PRoViDE project is compiling all Mars rover vision data into a database accessible through a web-GIS (PRoGIS) and 3D viewer (PRo3D). Stereo-imagery selected in PRoGIS can be rendered in PRo3D, enabling the user to zoom, rotate and translate the 3D outcrop model. Interpretations can be digitised directly onto the 3D surface, and simple measurements can be taken of the dimensions of the outcrop and sedimentary features. Dip and strike is calculated within PRo3D from mapped bedding contacts and fracture traces. Results from multiple outcrops can be integrated in PRoGIS to gain a detailed understanding of the geological features within an area. These tools have been tested on three case studies; Victoria Crater, Yellowknife Bay and Shaler. Victoria Crater, in the Meridiani Planum region of Mars, was visited by the MER-B Opportunity Rover. Erosional widening of the crater produced <15 m high outcrops which expose ancient Martian eolian bedforms. Yellowknife Bay and Shaler were visited in the early stages of the MSL mission, and provide excellent opportunities to characterise Martian fluvio-lacustrine sedimentary features. Development of these tools is crucial to exploitation of vision data from future missions, such as the 2018 ExoMars Rover and the NASA 2020 mission. The research leading to these results has received funding from the European Community's Seventh Framework Programme (FP7/2007-2013) under grant agreement n° 312377 PRoViDE.

Climate Change and European Water Bodies, a Review of Existing Gaps and Future Research Needs: Findings of the ClimateWater Project.

PubMed

Garnier, Monica; Harper, David M; Blaskovicova, Lotta; Hancz, Gabriella; Janauer, Georg A; Jolánkai, Zsolt; Lanz, Eva; Lo Porto, Antonio; Mándoki, Monika; Pataki, Beata; Rahuel, Jean-Luc; Robinson, Victoria J; Stoate, Chris; Tóth, Eszter; Jolánkai, Géza

2015-08-01

There is general agreement among scientists that global temperatures are rising and will continue to increase in the future. It is also agreed that human activities are the most important causes of these climatic variations, and that water resources are already suffering and will continue to be greatly impaired as a consequence of these changes. In particular, it is probable that areas with limited water resources will expand and that an increase of global water demand will occur, estimated to be around 35-60% by 2025 as a consequence of population growth and the competing needs of water uses. This will cause a growing imbalance between water demand (including the needs of nature) and supply. This urgency demands that climate change impacts on water be evaluated in different sectors using a cross-cutting approach (Contestabile in Nat Clim Chang 3:11-12, 2013). These issues were examined by the EU FP7-funded Co-ordination and support action "ClimateWater" (bridging the gap between adaptation strategies of climate change impacts and European water policies). The project studied adaptation strategies to minimize the water-related consequences of climate change and assessed how these strategies should be taken into consideration by European policies. This article emphasizes that knowledge gaps still exist about the direct effects of climate change on water bodies and their indirect impacts on production areas that employ large amounts of water (e.g., agriculture). Some sectors, such as ecohydrology and alternative sewage treatment technologies, could represent a powerful tool to mitigate climate change impacts. Research needs in these still novel fields are summarized.

Downstream changes of water quality in a lowland river due to groundwater inflows.

NASA Astrophysics Data System (ADS)

Zieba, Damian; Bar-Michalczyk, Dominika; Kania, Jarosław; Malina, Grzegorz; Michalczyk, Tomasz; Rozanski, Kazimierz; Witczak, Stanislaw; Wachniew, Przemyslaw; Zurek, Anna J.

2016-04-01

The Kocinka catchment (ca. 250 km2) in southern Poland receives substantial inflows of groundwater from a major fissured-carbonate aquifer polluted with nitrates originating from agriculture and domestic sewage. The 40 km long Kocinka river reveals large spatial variations in physical and chemical water properties with large downstream changes of nitrate concentrations. Detailed longitudinal surveys of such water characteristics as nitrate concentration, water temperature, pH, electric conductivity, stable isotopic composition, tritium concentration were performed in order to identify and quantify groundwater inflows. The river gains groundwater down to the 25 km from the source and a looses water further downstream. The subsequent increase and decrease of nitrate concentration in the upper and middle reaches of the river are caused by inflows of the, respectively, polluted and non-polluted groundwaters. The range of such changes can be even five-fold while the drop of nitrate concentration along the semi natural, 18 km long, lower reach where the river is well connected to its riparian and hyporheic zones nitrate loss is of the order of 10%. More significant nitrate losses were observed in the dammed reaches and in a small reservoir in the upper part of the river. Results of the study have implications for identification of measures that can be undertaken to reduce nitrate export from the catchment. Because of the role of groundwater in river runoff reduction of nitrate loads to the aquifer should be primary objective. Acknowledgements. The work was carried out as part of the BONUS Soils2Sea project on groundwater system (http:/www.soils2sea.eu) financed by the European Commission 7 FP contract 226536 and the statutory funds of the AGH University of Science and Technology (project No.11.11.140.026 and 11.11.220.01).

Methods of preparation and modification of advanced zero-valent iron nanoparticles, their properties and application in water treatment technologies

NASA Astrophysics Data System (ADS)

Filip, Jan; Kašlík, Josef; Medřík, Ivo; Petala, Eleni; Zbořil, Radek; Slunský, Jan; Černík, Miroslav; Stavělová, Monika

2014-05-01

Zero-valent iron nanoparticles are commonly used in modern water treatment technologies. Compared to conventionally-used macroscopic iron or iron microparticles, the using of nanoparticles has the advantages given mainly by their generally large specific surface area (it drives their high reactivity and/or sorption capacity), small dimensions (it allows their migration e.g. in ground water), and particular physical and chemical properties. Following the applications of zero-valent iron particles in various pilot tests, there arose several critical suggestions for improvements of used nanomaterials and for development of new generation of reactive nanomaterials. In the presentation, the methods of zero-valent iron nanoparticles synthesis will be summarized with a special attention paid to the thermally-induced solid-state reaction allowing preparation of zero-valent iron nanoparticles in an industrial scale. Moreover, the method of thermal reduction of iron-oxide precursors enables to finely tune the critical parameters (mainly particle size and morphology, specific surface area, surface chemistry of nanoparticles etc.) of resulting zero-valet iron nanoparticles. The most important trends of advanced nanoparticles development will be discussed: (i) surface modification of nanomaterilas, (ii) development of nanocomposites and (iii) development of materials for combined reductive-sorption technologies. Laboratory testing of zero-valent iron nanoparticles reactivity and migration will be presented and compared with the field observations: the advanced zero-valent iron nanoparticles were used for groundwater treatment at the locality contaminated by chlorinated hydrocarbons (VC, DCE, TCE and PCE) and reacted nanoparticles were extracted from the sediments for their fate assessment. The authors gratefully acknowledge the support by the Technology Agency of the Czech Republic "Competence Centres" (project No. TE01020218) and the EU FP7 (project NANOREM).

Arctic sea-ice variability and its implication to the path of pollutants under a changing climate

NASA Astrophysics Data System (ADS)

Castro-Morales, K.; Gerdes, R.; Riemann-Campe, K.; Köberle, C.; Losch, M.

2012-04-01

The increasing concentration of pollutants from anthropogenic origin in the Arctic atmosphere, water, sediments and biota has been evident during the last decade. The sea-ice is an important vehicle for pollutants in the Arctic Ocean. Pollutants are taken up by precipitation and dry atmospheric deposition over the snow and ice cover during winter and released to the ocean during melting. Recent changes in the sea-ice cover of the Arctic Ocean affect the fresh water balance and the oceanic circulation, and with it, the fate of pollutants in the system. The Arctic Ocean is characterized by complex dynamics and strong stratification. Thus, to evaluate the current and future changes in the Arctic circulation high-resolution models are needed. As part of the EU FP7 project ArcRisk (under the scope of the IPY), we use a high resolution regional sea-ice-ocean coupled model covering the Arctic Ocean and the subpolar North Atlantic based on the Massachusetts Institute of Technology - circulation model (MITgcm). Under realistic atmospheric forcing we obtain hindcast results of circulation patterns for the period 1990 - 2010 for validation of the model. We evaluate possible consequences on the pathways and transport of contaminants by downscaling future climate scenario runs available in the coupled model intercomparison project (CMIP3) for the following fifty years. Particular interest is set in the Barents Sea. In this shallow region strong river runoff, sea-ice delivered from the interior of the Arctic Ocean and warm waters from the North Atlantic current are main sources of contaminants. Under a changing climate, a higher input of contaminants delivered to surface waters is expected, remaining in the interior of the Arctic Ocean in a strongly stratified water column remaining.

Towards the mid-infrared optical biopsy

NASA Astrophysics Data System (ADS)

Seddon, Angela B.; Benson, Trevor M.; Sujecki, Slawomir; Abdel-Moneim, Nabil; Tang, Zhuoqi; Furniss, David; Sojka, Lukasz; Stone, Nick; Jayakrupakar, Nallala; Lloyd, Gavin R.; Lindsay, Ian; Ward, Jon; Farries, Mark; Moselund, Peter M.; Napier, Bruce; Lamrini, Samir; Møller, Uffe; Kubat, Irnis; Petersen, Christian R.; Bang, Ole

2016-03-01

We are establishing a new paradigm in mid-infrared molecular sensing, mapping and imaging to open up the midinfrared spectral region for in vivo (i.e. in person) medical diagnostics and surgery. Thus, we are working towards the mid-infrared optical biopsy (`opsy' look at, bio the biology) in situ in the body for real-time diagnosis. This new paradigm will be enabled through focused development of devices and systems which are robust, functionally designed, safe, compact and cost effective and are based on active and passive mid-infrared optical fibers. In particular, this will enable early diagnosis of external cancers, mid-infrared detection of cancer-margins during external surgery for precise removal of diseased tissue, in one go during the surgery, and mid-infrared endoscopy for early diagnosis of internal cancers and their precision removal. The mid-infrared spectral region has previously lacked portable, bright sources. We set a record in demonstrating extreme broad-band supercontinuum generated light 1.4 to 13.3 microns in a specially engineered, high numerical aperture mid-infrared optical fiber. The active mid-infrared fiber broadband supercontinuum for the first time offers the possibility of a bright mid-infrared wideband source in a portable package as a first step for medical fiber-based systems operating in the mid-infrared. Moreover, mid-infrared molecular mapping and imaging is potentially a disruptive technology to give improved monitoring of the environment, energy efficiency, security, agriculture and in manufacturing and chemical processing. This work is in part supported by the European Commission: Framework Seven (FP7) Large-Scale Integrated Project MINERVA: MId-to-NEaR- infrared spectroscopy for improVed medical diAgnostics (317803; www.minerva-project.eu).

Use of Lactobacillus plantarum fermentation products in bread-making to prevent Bacillus subtilis ropy spoilage.

PubMed

Valerio, Francesca; De Bellis, Palmira; Lonigro, Stella L; Visconti, Angelo; Lavermicocca, Paola

2008-03-20

Four fermentation products (FPs) of the lactic acid bacterium Lactobacillus plantarum ITM21B were screened for their anti-Bacillus activity in vitro and in bread-making trials. Results of the storage tests performed with loaves prepared with an FP or calcium propionate demonstrated that after 3 days at 30 degrees C, gross spoilage was evident in only the control loaves, which contained Bacillus subtilis at numbers of about 10(9) cfu/g. The highest inhibitory activity was shown by DM-FP obtained by growing L. plantarum in a defined medium (DM). Significantly, this medium contained an amino acceptor of the aminoacid transamination, namely alpha-ketoglutaric acid, and an aminoacid pool. With loaves prepared using the DM-acid mixture which simulated the DM-FP composition, the same reduction of ropy spoilage as with DM-FP was obtained after 3 days, while the efficacy of the mixture decreased after 7 days. This result suggests the potential involvement of some unknown metabolites in the inhibitory activity of DM-FP. In baked products made with flour based media (M1-FP, M2-FP, M3-FP), no ropy symptoms were noticeable after 3 days storage although a considerable Bacillus count was detected. DM-FP was as effective as calcium propionate (0.3% w/w, based on flour mass) in prolonging the Bacillus free-shelf life of yeast-leavened bread for 7 days.

Changes of Mediterranean cyclones in the future climate employing high resolution climate simulations

NASA Astrophysics Data System (ADS)

Hatzaki, M.; Flocas, H. A.; Kouroutzoglou, J.; Keay, K.; Simmonds, I.; Giannakopoulos, C. A.; Brikolas, V.

2011-12-01

A number of studies suggest that cyclone activity over both hemispheres has changed over the second half of the 20th century. The assessment of the future changes of the cyclonic activity as imposed by global warming conditions is very important since these cyclones can be associated with extreme precipitation conditions, severe storms and floods. This is more important for the Mediterranean that has been found to be more vulnerable to climate change. The main objective of the current study is to better understand and assess future changes in the main characteristics of Mediterranean cyclones, including temporal and spatial variations of frequency of cyclonic tracks, and dynamic and kinematic parameters, such as intensity, size, propagation velocity, as well as trend analysis. For this purpose, the MPI-HH regional coupled climate model of the Max Planck Institute for Meteorology is employed consisting of the REgional atmosphere MOdel (REMO), the Max-Planck-Institute for Meteorology ocean model (MPI-OM) and the Hydrological Discharge Model (HD Model). A 25 km resolution domain is established on a rotated latitude-longitude coordinate system, while the physical parameterizations are taken from the global climate model ECHAM-4. These model data became available through the EU Project CIRCE which aims to perform, for the first time, climate change projections with a realistic representation of the Mediterranean Sea. The model results for the present climate are evaluated against ERA-40 Reanalysis (available through ECMWF), for the period 1962-2001. The identification and tracking of cyclones is performed with the aid of the Melbourne University algorithm (MS algorithm), according to the Lagrangian perspective. MS algorithm characterizes a cyclone only if a vorticity maximum could be connected with a local pressure minimum. According to the results, a decrease of the storm number and a tendency towards deeper cyclones is expected in the future, in general agreement with the results of previous studies. However, new findings reveal with respect to the dynamic/kinematic characteristics of the cyclonic tracks. The model experiments verify that considerable inter-monthly variations of track density occur in the Mediterranean region. The study of the kinematic and dynamic parameters of the cyclonic tracks according to their origin domain show that the vast majority originate within the examined area itself. ACKNOWLEDGMENTS: M. Hatzaki would like to thank the Greek State Scholarships Foundation for financial support through the program of postdoctoral research. The support of EU-FP6 project CIRCE Integrated Project-Climate Change and Impact Research: the Mediterranean Environment (http://www.circeproject.eu) for climate model data provision is also greatly acknowledged.

A fate model for nitrogen dynamics in the Scheldt basin

NASA Astrophysics Data System (ADS)

Haest, Pieter Jan; van der Kwast, Johannes; Broekx, Steven; Seuntjens, Piet

2010-05-01

The European Union (EU) adopted the Water Framework Directive (WFD) in 2000 ensuring that all aquatic ecosystems meet ‘good ecological status' by 2015. However, the large population density in combination with agricultural and industrial activities in some European river basins pose challenges for river basin managers in meeting this status. The EU financed AQUAREHAB project (FP7) specifically examines the ecological and economic impact of innovative rehabilitation technologies for multi-pressured degraded waters. For this purpose, a numerical spatio-temporal model is developed to evaluate innovative technologies versus conventional measures at the river basin scale. The numerical model describes the nitrogen dynamics in the Scheldt river basin. Nitrogen is examined since nitrate is of specific concern in Belgium, the country comprising the largest area of the Scheldt basin. The Scheldt basin encompasses 20000 km2 and houses over 10 million people. The governing factors describing nitrogen fluxes at this large scale differ from the field scale with a larger uncertainty on input data. As such, the environmental modeling language PCRaster was selected since it was found to provide a balance between process descriptions and necessary input data. The resulting GIS-based model simulates the nitrogen dynamics in the Scheldt basin with a yearly time step and a spatial resolution of 1 square kilometer. A smaller time step is being evaluated depending on the description of the hydrology. The model discerns 4 compartments in the Scheldt basin: the soil, shallow groundwater, deep groundwater and the river network. Runoff and water flow occurs along the steepest slope in all model compartments. Diffuse emissions and direct inputs are calculated from administrative and statistical data. These emissions are geographically defined or are distributed over the domain according to land use and connectivity to the sewer system. The reactive mass transport is described using literature data. Process-knowledge on the innovative rehabilitation technologies, i.e. wetlands and riparian zones, will be derived from lab and field scale experiments. Datasets provided at the EU level are used to calibrate the model when available. The fate model will be used to create a database driven Decision Support System (DSS) in which costs of measures and ecotoxicological effects are considered. The DSS can then be used to compare alternative combinations of rehabilitation technologies versus conventional measures in the Scheldt river basin taking into account the ecological status of the river basin.

Demand for Modern Family Planning among Married Women Living with HIV in Western Ethiopia

PubMed Central

Feyissa, Tesfaye Regassa; Melka, Alemu Sufa

2014-01-01

Introduction People living with HIV (PLHIV) have diverse family planning (FP) needs. Little is reported on FP needs among women living with HIV in Ethiopia. Thus, the objective of the study was to assess the demand for modern FP among married women living with HIV in western Ethiopia. Methods A facility-based cross-sectional survey was conducted on 401 married women living with HIV selected from Nekemte Referral Hospital and Health Center, Nekemte, Oromia, Ethiopia. Convenience sampling of every other eligible patient was used to recruit respondents. Data were collected using a pretested, structured questionnaire. We first calculated frequency and percentage of unmet need, met need and total demand by each explanatory variable, and performed chi-squared testing to assess for differences in groups. We then fitted logistic regression models to identify correlates of unmet need for modern FP at 95% CL. Results The proportion of respondents with met need for modern FP among married women living with HIV was 61.6% (30.7% for spacing and 30.9% for limiting). Demand for family planning was reported in 77.0% (38.2% for spacing and 38.8% for limiting), making unmet need for modern FP prevalent in 15.4% (7.5% for spacing and 7.9% for limiting). Whereas age 25–34 years [adjusted odds ratio (AOR) (95% confidence interval (CI))  = .397 (.204–.771)] was protective against unmet need for modern FP, not having knowledge of MTCT [AOR (95% CI)  = 2.531 (1.689–9.290)] and not discussing FP with a partner [AOR (95% CI)  = 3.616(1.869–6.996)] were associated with increased odds of unmet need for modern FP. Conclusions There is high unmet need for modern FP in HIV-positive married women in western Ethiopia. Health care providers and program managers at a local and international level should work to satisfy the unmet need for modern family planning. PMID:25390620

Demand for modern family planning among married women living with HIV in western Ethiopia.

PubMed

Feyissa, Tesfaye Regassa; Melka, Alemu Sufa

2014-01-01

People living with HIV (PLHIV) have diverse family planning (FP) needs. Little is reported on FP needs among women living with HIV in Ethiopia. Thus, the objective of the study was to assess the demand for modern FP among married women living with HIV in western Ethiopia. A facility-based cross-sectional survey was conducted on 401 married women living with HIV selected from Nekemte Referral Hospital and Health Center, Nekemte, Oromia, Ethiopia. Convenience sampling of every other eligible patient was used to recruit respondents. Data were collected using a pretested, structured questionnaire. We first calculated frequency and percentage of unmet need, met need and total demand by each explanatory variable, and performed chi-squared testing to assess for differences in groups. We then fitted logistic regression models to identify correlates of unmet need for modern FP at 95% CL. The proportion of respondents with met need for modern FP among married women living with HIV was 61.6% (30.7% for spacing and 30.9% for limiting). Demand for family planning was reported in 77.0% (38.2% for spacing and 38.8% for limiting), making unmet need for modern FP prevalent in 15.4% (7.5% for spacing and 7.9% for limiting). Whereas age 25-34 years [adjusted odds ratio (AOR) (95% confidence interval (CI)) = .397 (.204-.771)] was protective against unmet need for modern FP, not having knowledge of MTCT [AOR (95% CI) = 2.531 (1.689-9.290)] and not discussing FP with a partner [AOR (95% CI) = 3.616(1.869-6.996)] were associated with increased odds of unmet need for modern FP. There is high unmet need for modern FP in HIV-positive married women in western Ethiopia. Health care providers and program managers at a local and international level should work to satisfy the unmet need for modern family planning.

The climate4impact portal: bridging CMIP5 data to impact users

NASA Astrophysics Data System (ADS)

Som de Cerff, Wim; Plieger, Maarten; Page, Christian; Hutjes, Ronald; de Jong, Fokke; Barring, Lars; Sjökvist, Elin

2013-04-01

Together with seven other partners (CERFACS, CNRS-IPSL, SMHI, INHGA, CMCC, WUR, MF-CNRM), KNMI is involved in the FP7 project IS-ENES (http://is.enes.org), which supports the European climate modeling infrastructure, in the work package 'Bridging Climate Research Data and the Needs of the Impact Community'. The aim of this work package is to enhance the use of climate model data and to enhance the interaction with climate effect/impact communities. The portal is based on 17 impact use cases from 5 different European countries, and is evaluated by a user panel consisting of use case owners. As the climate impact community is very broad, the focus is mainly on the scientific impact community. This work has resulted in a prototype portal, the ENES portal interface for climate impact communities, that can be visited at www.climate4impact.eu. The portal is connected to all Earth System Grid Federation (ESGF) nodes containing global climate model data (GCM data) from the fifth phase of the Coupled Model Intercomparison Project (CMIP5) and later from the Coordinated Regional Climate Downscaling Experiment (CORDEX). This global network of all major climate model data centers offers services for data description, discovery and download. The climate4impact portal connects to these services and offers a user interface for searching, visualizing and downloading global climate model data and more. A challenging task was to describe the available model data and how it can be used. The portal tries to inform users about possible caveats when using model data. All impact use cases are described in the documentation section, using highlighted keywords pointing to detailed information in the glossary. The current portal is a Prototype. It is built to explore state-of-art technologies to provide improved access to climate model data. The prototype will be evaluated and is the basis for development of an operational service. The portal and services provided will be sustained and supported during the development of these operational services (2013-2016) in the second phase of the FP7 IS-ENES project, ISENES2. In this presentation the architecture and following items will be detailed: • Security: Login using OpenID for access to the ESGF data nodes. The ESGF works in conjunction with several external websites and systems. The portal provides access to several distributed archives, most importantly the ESGF nodes. Single Sign-on (SSO) is used to let these websites and systems work together. • Discovery: Intelligent search based on e.g. variable name, model, institute. A catalog browser allows for browsing through CMIP5 and other climate model data catalogues (e.g. ESSENCE, EOBS, UNIDATA). • Download: Directly from ESGF nodes and other THREDDS catalogs • Visualization: Visualize any data directly on a map (ADAGUC Map services). • Transformation: Transform your data into other formats, perform basic calculations and extractions

Exploring reanalysis application for the purposes of climatological applications at regional scale

NASA Astrophysics Data System (ADS)

Kaspar, F.; Kaiser-Weiss, A.; Obregon, A.; Borsche, M.

2014-12-01

Recent advances in reanalysis methods yield new tools for climatological application. Here we use applications in Germany to discuss methodological issues at regional scale. Especially in the field of renewable energy planning and production there is a need for climatological information across all spatial scales, i.e., from climatology at a certain site to the spatial scale of national renewable energy production. Also, there is the need for the temporal resolution between the scales of a few minutes up to decadal changes. We explore the spatio-temporal scales where reanalyses can be used with benefit together with the traditional approaches which are based on station measurements only. Reanalyses can provide valuable additional information on larger scale variability, e.g. multi-annual variation over Germany. However, the change in the observing system, model errors and biases have to be carefully considered. On the other hand, the ground-based observation networks suffer from change of the station distribution, changes in instrumentation, measurements procedures and quality control as well as local changes which might modify their spatial representativity. All these effects might often been unknown or hard to characterize, although plenty of the meta-data information has been recorded for the German stations. European research activities on global and regional reanalysis are supported by the Framework Program 7 (FP7) of the European Commission as a preparation activity for the European COPERNICUS climate change service. Here we start from the user requirements for reanalyses as they were collected in the FP7 project CORE-CLIMAX. Second, we give an overview over the methods to determine whether a specific reanalysis is fit for a certain purpose (discussed in FP7 projects CORE-CLIMAX and UERRA) . Thirdly, we compare for an example application the feedback statistics from global (ERA-Interim) and regional (HErZ - COSMO) reanalyses and show which conclusion can be drawn. Finally, the wind climatologies derived from the different reanalyses (ERA-Interim, ERA-20C, HErZ-COSMO) are compared with point measurements and gridded field climatologies derived from ground-based stations, illustrating the added value of the reanalysis fields.

Women's development key to MCH/FP.

PubMed

1991-05-01

The Sri Lankan government has included women in its development process thereby raising literacy levels to 91% for urban women and 87% for rural women. Their successful participation has in turn resulted in improvements in maternal and child health (MCH) and family planning (FP) acceptance. Indeed MCH/FP promotion could not have occurred without their participation in development. Since the 1960s, the Health and Women's Affairs Ministry continues to provide broad support for grass roots health care, such as strengthening the capacity of local clinics to increase coverage of health monitoring for women and children. There fore infant mortality in Sri Lanka has decreased from 47.5 in 1970 to 34 in 1980 to 19 in 1989. In addition, the total fertility rate fell from 5 in 1962-1964 to 3.4 in 1980-1982 to 2.8 in 1982-1987. The Ministry initiated its Integrated FP, Nutrition, and Parasite Control Project (IP) in 8 pilot areas in 1981. IP continues to encourage women's developed and MCH/FP at the grass roots level. In fact, FP acceptance rates increased from 31.8% in 1980 to 59% in 1989 in Nakulugamuwa and from 2.3% in 1980 to 70.5% in 1989 in Galnewa. The MCH component operating from community level clinics includes growth monitoring and immunization. Project activities include construction of latrines and wells, promotion of regular health examinations for mothers and children, FP education, counseling, nutrition promotion for children, and training programs for health staff, community volunteers, mothers' groups, and teachers. The volunteers form a link between the community and government health workers. Mothers' groups participate in school nutrition programs, home gardening, and income generation. Parasite control is consequently accomplished by community health and environmental sanitation promotion.

HELIO: The Heliophysics Integrated Observatory

NASA Technical Reports Server (NTRS)

Bentley, R. D.; Csillaghy, A.; Aboudarham, J.; Jacquey, C.; Hapgood, M. A.; Bocchialini, K.; Messerotti, M.; Brooke, J.; Gallagher, P.; Fox, P.;

InSAR analysis of the crustal deformation affecting the megacity of Istanbul: the results of the FP7 Marsite Project as a GEO Supersite Initiative

NASA Astrophysics Data System (ADS)

Solaro, Giuseppe; Bonano, Manuela; Manzo, Mariarosaria

2016-04-01

The North Anatolian Fault (NAF) is one of the most active faults worldwide, extending approximately 1,200 km from Eastern Turkey to the Northern Aegean Sea. During the 20th century series of damaging earthquakes occurred along the NAF, generally propagated westward towards Istanbul; the last one occurred in 1999 at Izmit, a city 80 km away from Istanbul. Within this scenario, the FP7 MARsite project (New Directions in Seismic Hazard assessment through Focused Earth Observation in Marmara Supersite), supported by EU, intends to collect, share and integrate multidisciplinary data (seismologic, geochemical, surveying, satellite, etc.) in order to carry out assessment, mitigation and management of seismic risk in the region of the Sea of Marmara. In the framework of the MARsite project, we performed the analysis and monitoring of the surface deformation affecting the Istanbul mega city by exploiting the large archives of X-band satellite SAR data, made available through the Supersites Initiatives, and by processing them via the advanced multi-temporal and multi-scale InSAR technique, known as the Small BAseline Subset (SBAS) approach. In particular, we applied the SBAS technique to a dataset of 101 SAR images acquired by the TerraSAR-X constellation of the German Space Agency (DLR) over descending orbits and spanning the November 2010 - August 2014 time interval. From,these images, we generated 312 differential interferograms with a maximum spatial separation (perpendicular baseline) between the acquisition orbits of about 500 m., that were used to generate, via the SBAS approach, mean deformation velocity map and corresponding ground time series of the investigated area. The performed InSAR analysis reveals a generalized stability over the Istanbul area, except for some localized displacements, related to subsidence and slope instability phenomena. In particular, we identified: (i) a displacement pattern related to the Istanbul airport, showing a mostly linear deformation trend with a velocity of about 1 cm/yr, although a slowdown effect is observed starting from early 2014, and (ii) a subsidence phenomenon in correspondence to Miniaturk park with a mean velocity value of about 1.5 cm/yr. Moreover, by benefiting from the recent launch of the C-band Sentinel-1A (S1A) satellite (April 2014), developed within the European Commission Copernicus Programme, we performed a more recent InSAR analysis of the Istanbul mega city and its surroundings by exploiting datasets collected during the October 2014 - December 2015 time interval. In such a way, we are able to investigate possible changes in the spatial and temporal deformation rates of the detected displacements over time with the aim to improve the comprehension of the deformation processes already occurred and/or occurring in this area. The obtained results, generated within the MARsite project, are expected to be available to scientific community through the Geohazards Exploitation Platform (GEP), an ESA platform aimed at supporting the exploitation of satellite EO data for geohazards, to be fully compliant with some of the major issues of the Supersites Initiative, as well as to foster the InSAR data sharing within a wider scientific community.

The climate4impact portal: bridging the CMIP5 data infrastructure to impact users

NASA Astrophysics Data System (ADS)

Plieger, Maarten; Som de Cerff, Wim; Page, Christian; Hutjes, Ronald; de Jong, Fokke; Bärring, Lars; Sjökvist, Elin

2013-04-01

Together with seven other partners (CERFACS, CNRS-IPSL, SMHI, INHGA, CMCC, WUR, MF-CNRM), KNMI is involved in the FP7 project IS-ENES (http://is.enes.org), which supports the European climate modeling infrastructure, in the work package 'Bridging Climate Research Data and the Needs of the Impact Community'. The aim of this work package is to enhance the use of climate model data and to enhance the interaction with climate effect/impact communities. The portal is based on 17 impact use cases from 5 different European countries, and is evaluated by a user panel consisting of use case owners. As the climate impact community is very broad, the focus is mainly on the scientific impact community. This work has resulted in a prototype portal, the ENES portal interface for climate impact communities, that can be visited at www.climate4impact.eu. The portal is connected to all Earth System Grid Federation (ESGF) nodes containing global climate model data (GCM data) from the fifth phase of the Coupled Model Intercomparison Project (CMIP5) and later from the Coordinated Regional Climate Downscaling Experiment (CORDEX). This global network of all major climate model data centers offers services for data description, discovery and download. The climate4impact portal connects to these services and offers a user interface for searching, visualizing and downloading global climate model data and more. A challenging task was to describe the available model data and how it can be used. The portal tries to inform users about possible caveats when using GCM data. All impact use cases are described in the documentation section, using highlighted keywords pointing to detailed information in the glossary. During the project, the content management system Drupal was used to enable partners to contribute on the documentation section. In this presentation the architecture and following items will be detailed: - Security: Login using OpenID for access to the ESG data nodes. The ESG works in conjunction with several external websites and systems. The climate4impact portal uses X509 based short lived credentials, generated on behalf of the user with a MyProxy service. Single Sign-on (SSO) is used to make these websites and systems work together. - Discovery: Facetted search based on e.g. variable name, model and institute using the ESG search services. A catalog browser allows for browsing through CMIP5 and other climate model data catalogues (e.g. ESSENCE, EOBS, UNIDATA). - Download: Directly from ESG nodes and other THREDDS catalogs - Visualization: Visualize any data directly using ADAGUC dynamic Web Map Services. - Transformation: Transform your data into other formats, perform basic calculations and extractions using OCG Web Processing Services The current portal is a Prototype. It is built to explore state-of-art technologies to provide improved access to climate model data. The prototype will be evaluated and is the basis for development of an operational service. The portal and services provided will be sustained and supported during the development of these operational services (2013-2016) in the second phase of the FP7 IS-ENES project, ISENES2.

Preliminary results of the PREFER FP7 Project

NASA Astrophysics Data System (ADS)

Fusilli, Lorenzo; Laneve, Giovanni; De Bonis, Roberto; Sebastian, Ana; Ferrucci, Fabrizio; Oliveira, Sandra

2014-05-01

The need to improve the information and intelligence support for forest fire prevention is widely recognized. Fire prevention is still the most cost-effective strategy when compared to firefighting and extinguishing that are costly, local, and triggered only in response to already ongoing crises. PREFER project, funded under the EU FP7 (G.A. 312931), intends to contribute at responding to such a pragmatic need of southern Europe's forests by: providing timely information products based on the exploitation of all available spacecraft sensors, offering a portfolio of products focused on pre- and post-crisis forest fire emergency, suitable for the users in the different countries of the European Mediterranean area. The PREFER Service portfolio consists of two main services: 1. Information Support to Fire Preparedness/Prevention Phase" (ISP) Service 2. Information Support to Fire Recovery/Reconstruction Phase" (ISR) Service This service is already at an advanced stage having completed the first year of activity. During this time several products have been consolidated: seasonal fuel maps; daily and seasonal fire hazard maps; seasonal risk maps; prescribed fire maps. This paper aims at presenting the preliminary results of the research activity carried out in the framework of the PREFER project, focusing, in particular, on these recalled above. As for Fire Risk and Hazard assessment, many indexes have been developed in the last years. Hardly any of them uses data derived from satellite images. The FPI index is an exception to this rule which, in addition, makes use of meteorological data. In spite of being a very complete index, the FPI still allows room for improvement which justify the interest of PREFER in it. PREFER's innovative approach to FPI will allow taking into account the effect of solar illumination conditions in determining the humidity present in the dead vegetation, and therefore its proneness to burn. PREFER innovation also focus in allowing the index to take into account the influence of water present in the alive vegetation (relevant in determining the fire regime) through the Equivalent Water Thickness. PREFER will use daily FPI forecasts to produce a seasonal fire hazard index by introducing in the model the human factor as captured by the fire occurrence statistics. PREFER will produce also seasonal fire risk maps by combining the seasonal hazard data with vulnerability and exposure maps. Finally, Prescribed Burning (PB) represents the controlled application of fire to vegetation under specific environmental conditions to attain planned resource management objectives. The main objective of the PREFER service for PB is to support the user in the identification of the areas and the time, that is where and when, the PB practice is applicable in a secure way. The main innovation, taking into account the results previously obtained in the frame work of other European projects (FIREPARADOX), will be the integration of the advanced remote sensing techniques that have not yet been developed for the problem under study, aiming at developing an index capable to provide the right time to intervene with the PB in the area of interest.

The Guardian. Volume 13, Issue 1, Spring 2011

DTIC Science & Technology

2011-01-01

PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES...Furthermore, there were no AT standards pertaining to design, material, or construction of new and existing buildings ; building standoff requirements; or...installations or forward-deployed areas; DOD-wide anti¬terrorism building standards for construction , standoff, and so forth; and regular FP exercises held at

Enabling Virtual Access to Latin-American Southern Observatories

NASA Astrophysics Data System (ADS)

Filippi, G.

2010-12-01

EVALSO (Enabling Virtual Access to Latin-American Southern Observatories) is an international consortium of nine astronomical organisations and research network operators, part-funded under the European Commission FP7, to create and exploit high-speed bandwidth connections to South American observatories. A brief description of the project is presented. The EVALSO Consortium inaugurated a fibre link between the Paranal Observatory and international networks on 4 November 2010 capable of 10 Gigabit per second.

Estimating the impact of +2 degrees of global warming on European Tourism

NASA Astrophysics Data System (ADS)

Tsanis, Ioannis; Koutroulis, Aristeidis; Grillakis, Manolis; Konstantopoulos, Konstantinos; Jacob, Daniela

2014-05-01

The impact of a potential global temperature rise by 2oC on tourism is examined, within the framework of IMPACT2C FP7 project. The period of the specific increase was defined according to the global mean temperature projections from two GCM, BCM and HadCM3Q3. Simulations from two RCMs, driven by the aforementioned GCMs, in the frame of ENSEMBLES FP6 under A1B emission scenario were used to estimate the Tourism Climatic Index (TCI) which is a measure of climate favorability for outdoor leisure and recreational activities. Climate favorability related to summer tourism is expected to increase in most European countries moving from south to north. In the opposite, countries that traditionally attract "sun and sand" tourists like Italy, Spain, Greece, France, Portugal, Cyprus are projected to become uncomfortably hot for the months of the peak summer season. Both of the examined models provide consistent information about the direction of change, however SMHI shows a greater change in future TCI. The TCI between 1960 and 2000 was associated to bednights data, to reveal the correlation of the empirical index with a real tourism indicator. The resulted correlation function was then applied to the 2oC period, estimating the effect of the specific temperature rise to future tourism activity expressed in terms of projected bednights.

Role and goals of the EUR-OCEANS Consortium - Bringing marine scientists priorities and strategies to the European research planning agenda.

NASA Astrophysics Data System (ADS)

Cury, Philippe; Baisnée, Pierre-François

2010-05-01

The EUR-OCEANS Consortium is the follow-up structure of the homonym European Network of Excellence (NoE; 2005-2008, FP6 contract number 511106). It is a scientific network, benefiting from and relying upon the institutional commitment of the 27 research performing organisations forming its core (paying) membership. It aims at the long-term harmonization of European research efforts related to ocean ecosystems undergoing anthropogenic and natural forcing. More specifically, its objectives are to facilitate and promote: (1) top-level scientific research on the impacts of anthropogenic and natural forcing on ocean ecosystems, fostering collaborations across the European Research Area; (2) the optimal use of any shared technical infrastructures and scientific facilities; and (3) activities to spread excellence, such as the training of scientific personnel and students, or knowledge dissemination towards the general public and socio-economic users. A particular focus is put during the first scientific coordination mandate on the building of scenarios for marine ecosystems under anthropogenic and natural forcing in the XXI Century, and on the improvement of the science-policy interface. Through calls for projects and networking activities, the Consortium seeks to favour the emergence of coordinated projects on key hot topics on one hand, and the crystallisation of scientific priorities and strategies that could serve as input to ERA-NETs, ESFRI, Joint Programming Initiatives and European Research Planning actors in general. While being an active standalone structure, the Consortium is also engaged in the Euromarine FP7 project (submitted) aiming at the definition of a common coordinating or integrating structure for the three follow-up entities of FP6 marine science NoEs (Marine Genomics Europe, MarBEF, EUR-OCEANS). The 2009-2011 strategy and activity plan of EUR-OCEANS will be presented and the involvement of EUR-OCEANS members in other key projects or programmes will be summarized.

Urban impact on air quality in RegCM/CAMx couple for MEGAPOLI project - high resolution sensitivity study

NASA Astrophysics Data System (ADS)

Halenka, T.; Huszar, P.; Belda, M.

2010-09-01

Recent studies show considerable effect of atmospheric chemistry and aerosols on climate on regional and local scale. For the purpose of qualifying and quantifying the magnitude of climate forcing due to atmospheric chemistry/aerosols on regional scale, the development of coupling of regional climate model and chemistry/aerosol model was started on the Department of Meteorology and Environmental Protection, Charles University, Prague, for the EC FP6 Project QUANTIFY and EC FP6 Project CECILIA. For this coupling, existing regional climate model and chemistry transport model have been used at very high resolution of 10km grid. Climate is calculated using RegCM while chemistry is solved by CAMx. The experiments with the couple have been prepared for EC FP7 project MEGAPOLI assessing the impact of the megacities and industrialized areas on climate. Meteorological fields generated by RCM drive CAMx transport, chemistry and a dry/wet deposition. A preprocessor utility was developed for transforming RegCM provided fields to CAMx input fields and format. New domain have been settled for MEGAPOLI purpose in 10km resolution including all the European "megacities" regions, i.e. London metropolitan area, Paris region, industrialized Ruhr area, Po valley etc. There is critical issue of the emission inventories available for 10km resolution including the urban hot-spots, TNO emissions are adopted for this sensitivity study in 10km resolution for comparison of the results with the simulation based on merged TNO emissions, i.e. basically original EMEP emissions at 50 km grid. The sensitivity test to switch on/off Paris area emissions is analysed as well. Preliminary results for year 2005 are presented and discussed to reveal whether the concept of effective emission indices could help to parameterize the urban plume effects in lower resolution models. Interactive coupling is compared to study the potential of possible impact of urban air-pollution to the urban area climate.

The approach of the PREFER project to wildfire prevention and damage assessment in the Mediterranean area

NASA Astrophysics Data System (ADS)

Laneve, Giovanni; Fusilli, Lorenzo; Tampellini, Maria Lucia; Vimercati, Marco; Hirn, Barbara; Sebastian-Lopez, Ana; Diagourtas, Dimitri; Eftychidis, Georgios; Clandillon, Stephen; Caspard, Mathilde; Oliveira, Sandra; Lourenco, Luciano

2015-04-01

PREFER is a Copernicus Emergency project funded from the 2012 FP7 Space Work Programme, and it is aimed at developing products and services that will contribute to improve the European capacity to respond to the preparedness, prevention, and recovery management steps in the case of forest fire emergency cycle, with focus on the Mediterranean area. It is well known from the most recent reports on state of Europe's forests that the Mediterranean area is particularly affected by uncontrolled forest fires, with a number of negative consequences on ecosystems, such as desertification and soil erosion, and on the local economy. Most likely, the current risks of forest fires will be exacerbated by climate change. In particular, the climate of Southern Europe and the Mediterranean basin is projected to warm at a rate exceeding the global average. Wild fires will therefore remain the most serious threat to Southern European forests. In this situation, the need to collect better information and more knowledge concerning future risks of forest fires and fire prevention in the Mediterranean area is widely recognized to be a major urgent one. As part of the Copernicus programme (i.e. the European Earth Observation Programme), PREFER is based on advanced geo-information products using in particular the earth observation data acquired and developed in the frame of Copernicus. The objective of the PREFER project, started at the end of 2012, 8 partners (from Italy, Portugal, Spain, France and Greece) involved and three years schedule, is the design, development and demonstration of a pre-operational "end-to-end" information service, fully exploiting satellite sensors data and able to support prevention/ preparedness and recovery phases of the Forest Fires emergency cycle in the EU Mediterranean Region. The PREFER information is as general as to be usable in the different countries of the Mediterranean Region, and acts in full complement to already existing services, such as the EC JRC EFFIS System. This paper intends to provide a concise report about and major highlights and achievements of the PREFER project research and development phase, along with the first results of the demonstration activities and users' feedbacks.

Passive vs Active Knowledge Transfer: boosting grant proposal impact

NASA Astrophysics Data System (ADS)

Grigorov, Ivo; Bayliss-Brown, Georgia; Murphy, David; Thøgersen, Thomas; Mariani, Patrizio

2017-04-01

Research funders are increasingly concerned with measurable socio-economic impact of investment in research, and on increasingly shorter timescales. Innovation, and "open innovation" are the policy priorities of the moment and optimising the flow of ideas along the lab-2-market spectrum is essential for re-use of results, fuelling open innovation, and boosting socio-economic impact or public funded research. The presentation showcases two complimentary strategies that Project Managers can employ pre- and/or post-award in order to optimise the exploitation and impact of research project: passive and active knowledge transfer. Passive Knowledge Transfer relies on maximum disclosure of research output (other than commercially exploitable research via patents and other IPR) in the interest of optimal reproducibility, independent validation and re-use by both academic and non-academic users, without necessarily targeting specific users. Tools of the trade include standard public & academic dissemination means (research articles, online media publications, newsletters, generic policy briefs). Additional transparency of the research workflow can be achieved by integrating "open science" (open notebooks, open data, open research software and open access to research publications) as well as Virtual Research Environments (VREs) in the methodology of the proposed work. Ensuring that the proposal partners are suitably trained in best practices of open science, makes proposal grant more competitive at evaluation and the resulting maximum access to research outputs does contribute to better return on investment for funders (Beagrie 2016) and economic growth objectives of public s e.g. Blue Growth (Houghton & Swan 2011, Marine Knowledge 2020 Roadmap). Active Knowledge Transfer, or the pro-active translation of research into policy or commercial context, is the more classical and better known approach (also referred to as extension services, or researchers providing advice e.g. to fisheries and aquaculture governance bodies and private sector). Horizon2020 COLUMBUS Consortium proposes and tests a methodology for categorizing the diverse output of research into verifiable "knowledge outputs" , and documenting the execution of an transfer plan to very specific and identified potential users, in order to transfer knowledge along the lab-2-market spectrum. The presentation will demonstrate how Open Science and detailed knowledge transfer plans complement each other, enhance grant proposal evaluation pre- and post-award, and can address Blue Growth policy objectives. Concepts presented are developed by FP7/H2020 FOSTER (www.fosteropenscience.eu), H2020 COLUMBUS (www.columbusproject.eu) References: Beagrie, Neil, and Charles Beagrie. "The Value and Impact of the European Bioinformatics Institute," January 2016. http://www.beagrie.com/static/resource/EBI-impact-report.pdf Houghton, John, Alma Swan, and Sheridan Brown. "Access to Research and Technical Information in Denmark." Monograph, April 2011. http://eprints.soton.ac.uk/272603/ Marine Knowledge 2020: roadmap http://eur-lex.europa.eu/legal-content/EN/TXT/?uri=SWD:2014:149:FIN

Explaining the Mathematical Creativity of a Young Boy: An Interdisciplinary Venture between Mathematics Education and Psychoanalysis

ERIC Educational Resources Information Center

Krummheuer, Götz; Leuzinger-Bohleber, Marianne; Müller-Kirchof, Marion; Münz, Melanie; Vogel, Rose

2013-01-01

First results of the project "Mathematical Creativity of Children at Risk" (MaKreKi) will be presented. The project is conducted in the interdisciplinary research center "Individual Development and Adaptive Education of Children at Risk" (IDeA [http://www.idea-frankfurt.eu; accessed 7 June 2013]). Combining a…

Astronomical Infrastructure for Data Access (AIDA): service activities for higher education and outreach

NASA Astrophysics Data System (ADS)

Iafrate, G.; Ramella, M.; Boch, T.; Bonnarel, F.; Chèreau, F.; Fernique, P.; Osuna, P.

2009-04-01

We present preliminary simple interfaces developed to enable students, teachers, amateur astronomers and general public to access and use the wealth of astronomical data available in ground-based and space archives through the European Virtual Observatory (EuroVO). The development of these outreach interfaces are the aim of a workpackage of EuroVO-AIDA (Astronomical Infrastructure for Data Access), a project supported by EU in the framework of the FP7 Infrastructure Scientific Research Repositories initiative (project RI2121104). The aim of AIDA is to create an operating infrastructure enabling and stimulating new scientific usage of astronomy digital repositories. Euro VO AIDA is a collaboration between six European countries (PI Francoise Genova, CDS). The professional tools we adapt to the requirements of outreach activities are Aladin (CDS), Stellarium/VirGO (ESO) and VOSpec (ESA VO). Some initial requirements have been set a priori in order to produce a first version of the simplified interfaces, but the plan is to test the initial simplified versions with a sample of target users in order to take their feed-back into account for the development of the final outreach interface. The core of the test program consists of use cases we designed and complemented with proper multilingual documentation covering both the astrophysical context and the use of the software. In the special case of students in the age group 14-18 and their teachers, we take our use cases to schools. We work out the tests in classrooms supporting students working on PCs connected to the internet. At the current stage of the project, we are collecting the users feedback. Relevant links: Euro-VO AIDA Overview http://www.euro-vo.org/pub/aida/overview.html Euro-VO AIDA WP5 http://cds.u-strasbg.fr/twikiAIDA/bin/view/EuroVOAIDA/WP5WorkProgramme

Toward a Model-Based Approach to Flight System Fault Protection

NASA Technical Reports Server (NTRS)

Day, John; Murray, Alex; Meakin, Peter

2012-01-01

Fault Protection (FP) is a distinct and separate systems engineering sub-discipline that is concerned with the off-nominal behavior of a system. Flight system fault protection is an important part of the overall flight system systems engineering effort, with its own products and processes. As with other aspects of systems engineering, the FP domain is highly amenable to expression and management in models. However, while there are standards and guidelines for performing FP related analyses, there are not standards or guidelines for formally relating the FP analyses to each other or to the system hardware and software design. As a result, the material generated for these analyses are effectively creating separate models that are only loosely-related to the system being designed. Development of approaches that enable modeling of FP concerns in the same model as the system hardware and software design enables establishment of formal relationships that has great potential for improving the efficiency, correctness, and verification of the implementation of flight system FP. This paper begins with an overview of the FP domain, and then continues with a presentation of a SysML/UML model of the FP domain and the particular analyses that it contains, by way of showing a potential model-based approach to flight system fault protection, and an exposition of the use of the FP models in FSW engineering. The analyses are small examples, inspired by current real-project examples of FP analyses.

Short- term effects of post-fire logging on runoff and soil erosion at two spatial scales

NASA Astrophysics Data System (ADS)

Malvar, Maruxa; Silva, Flavio; Prats, Sergio; Vieira, Diana; Keizer, Jacob

2017-04-01

Logging is the most common management practice after wildfires in forested areas in Portugal. Clearcutting is undertaken to recover burnt timber resources, to control resprouting, notably in the case of eucalypt plantations, and to reduce the risks of possible insect plagues, notably in the case of maritime pine because of the nematode plague. Still, relatively little is known about the combined effect of wildfire and post-fire logging on erosion processes. In the framework of the EU-FP7 project RECARE (www.recare-project.eu), the ESP team of the University of Aveiro set up an experiment to quantify the hydrological and erosion impacts of post-fire logging, at the scale of both 0.25 m2 micro-plots and 16 m2 plots. A eucalypt slope burnt in August 2015 by a moderate intensity fire and logged in September 2015 was selected for this study. The burned trees were harvested with a chainsaw, while the logs were piled with a rubber wheeled forwarder tractor. Following logging, two distinct sub-areas were identified within the logged slope based on soil disturbance: an area where the forwarder wheels had left marked trails ("trail"), and an area where such trails were absent ("control"). Three micro-plots and three plots were installed in the control area, while three micro-plots and six plots were installed in the trail area. Generally, the trail area showed greater soil compaction and larger soil surface roughness than the control area. Between October 2015 and September 2016, mean runoff was 500 mm in the control micro-plots and 50% higher in the trail micro-plots. At the plot scale, however, no differences in runoff generation were observed between the two subareas. Sediment production over the same period, however, was twice as high in the trail area than the control area, at both plot scales. In the control area, mean sediment production was 8 Mg ha-1 yr-1 at the micro-plot scale and 6 Mg ha-1 yr-1at the plot scale; in the trail area, these figures were 21 Mg ha-1 yr-1 and 13 Mg ha-1 yr-1, respectively. Post-fire logging activities and their timing should be evaluated against their potential impacts on runoff and erosion, and should be contemplated for additional erosion mitigation practices.

Impacts of Electric Propulsion Systems on Submarine Design

DTIC Science & Technology

1989-06-01

in oersteds D = the density of the steel in grams per cubic centimeter p = the elec" .,; al resistivity of the steel in microohm-centimeters N = the...Condition Al (Sum W1-W7) 4138.64 144.09 15.24 Lead Ballast 413.86 142.50 13.70 Condition A 4552.50 143.95 15.1 Variable Load Weights 209.53 87.46 9.86...fscanf(fp, "%lf", &lr); fscanf(fp, *W%lf?, &vol); fscanf(fp, "%lf", &wt.); fac~ azif (f p, "%lf" &ph); fscant (fp, "%If, &pe); fscanf(fp, "%lf" &i2r

Use of Simulation in Nursing Education: Initial Experiences on a European Union Lifelong Learning Programme--Leonardo Da Vinci Project

ERIC Educational Resources Information Center

Terzioglu, Fusun; Tuna, Zahide; Duygulu, Sergul; Boztepe, Handan; Kapucu, Sevgisun; Ozdemir, Leyla; Akdemir, Nuran; Kocoglu, Deniz; Alinier, Guillaume; Festini, Filippo

2013-01-01

Aim: The aim of this paper is to share the initial experiences on a European Union (EU) Lifelong Learning Programme Leonardo Da Vinci Transfer of Innovation Project related to the use of simulation-based learning with nursing students from Turkey. The project started at the end of the 2010 involving 7 partners from 3 different countries including…

Nonpharmacologic control of postoperative supraventricular arrhythmias using AV nodal fat pad stimulation in a young animal open heart surgical model.

PubMed

Moak, Jeffrey P; Mercader, Marco A; He, Dingchao; Trachiotis, Gregory; Langert, Joshua; Blicharz, Andy; Montaque, Erin; Li, Xiyan; Cheng, Yao I; McCarter, Robert; Bornzin, Gene A; Martin, Gerard R; Jonas, Richard A

2013-06-01

Supraventricular arrhythmias (junctional ectopic tachycardia [JET] and atrial tachyarrhythmias) frequently complicate recovery from open heart surgery in children and can be difficult to manage. Medical treatment of JET can result in significant morbidity. Our goal was to develop a nonpharmacological approach using autonomic stimulation of selective fat pad (FP) regions of the heart in a young canine model of open heart surgery to control 2 common postoperative supraventricular arrhythmias. Eight mongrel dogs, varying in age from 5 to 8 months and weighting 22±4 kg, underwent open heart surgery replicating a nontransannular approach to tetralogy of Fallot repair. Neural stimulation of the right inferior FP was used to control the ventricular response to supraventricular arrhythmias. Right inferior FP stimulation decreased baseline AV nodal conduction without altering sinus cycle length. AV node Wenckebach cycle length prolonged from 270±33 to 352±89 ms, P=0.02. Atrial fibrillation occurred in 7 animals, simulating a rapid atrial tachyarrhythmias. FP stimulation slowed the ventricular response rate from 166±58 to 63±29 beats per minute, P<0.001. Postoperative JET occurred in 7 dogs. FP stimulation slowed the ventricular rate during postoperative JET from 148±31 to 106±32 beats per minute, P<0.001, and restored sinus rhythm in 7/7 dogs. Right inferior FP stimulation had a selective effect on the AV node, and slowed the ventricular rate during postoperative JET and atrial tachyarrhythmias in our young canine open heart surgery model. FP stimulation may be a useful new technique for managing children with JET and atrial tachyarrhythmias.

Interoperability challenges in river discharge modelling: A cross domain application scenario

NASA Astrophysics Data System (ADS)

Santoro, Mattia; Andres, Volker; Jirka, Simon; Koike, Toshio; Looser, Ulrich; Nativi, Stefano; Pappenberger, Florian; Schlummer, Manuela; Strauch, Adrian; Utech, Michael; Zsoter, Ervin

2018-06-01

River discharge is a critical water cycle variable, as it integrates all the processes (e.g. runoff and evapotranspiration) occurring within a river basin and provides a hydrological output variable that can be readily measured. Its prediction is of invaluable help for many water-related tasks including water resources assessment and management, flood protection, and disaster mitigation. Observations of river discharge are important to calibrate and validate hydrological or coupled land, atmosphere and ocean models. This requires using datasets from different scientific domains (Water, Weather, etc.). Typically, such datasets are provided using different technological solutions. This complicates the integration of new hydrological data sources into application systems. Therefore, a considerable effort is often spent on data access issues instead of the actual scientific question. This paper describes the work performed to address multidisciplinary interoperability challenges related to river discharge modeling and validation. This includes definition and standardization of domain specific interoperability standards for hydrological data sharing and their support in global frameworks such as the Global Earth Observation System of Systems (GEOSS). The research was developed in the context of the EU FP7-funded project GEOWOW (GEOSS Interoperability for Weather, Ocean and Water), which implemented a "River Discharge" application scenario. This scenario demonstrates the combination of river discharge observations data from the Global Runoff Data Centre (GRDC) database and model outputs produced by the European Centre for Medium-Range Weather Forecasts (ECMWF) predicting river discharge based on weather forecast information in the context of the GEOSS.

Nanoparticles migration in fractured rocks and affects on contaminant migration

NASA Astrophysics Data System (ADS)

Missana, Tiziana; Garcia-Gutierrez, Miguel; Alonso, Ursula

2014-05-01

In previous studies, the transport behavior of artificial (gold and latex) and natural (smectite clay) colloids, within a planar fracture in crystalline rock, was analyzed. In order to better understand the effects of colloid size, shape and surface charge on nanoparticle migration and especially on filtration processes on natural rock surfaces, different clay colloids and oxide nanoparticles were selected and their transport studied as a function of the residence time. In all the cases, (a fraction of) the nanoparticles travelled in the fracture as fast as or faster than water (with a retardation factor, Rf ≤ 1) and the observed Rf, was related to the Taylor dispersion coefficient, accounting for colloid size, water velocity and fracture width. However, under most of the cases, in contrast to the behavior of a conservative tracer, colloids recovery was much lower than 100 %. Differences in recovery between different nanoparticles, under similar residence times, were analyzed. In order to evaluate the possible consequences, on contaminant migration, of the presence of nanoparticles in the system, transport tests were carried out with both colloids and sorbing radionuclides. The overall capacity for colloids of enhancing radionuclide migration in crystalline rock fractures is discussed. Acknowledgments: The research leading to these results received funding from EU FP7/2007-2011 grant agreement Nº 295487 (BELBAR, Bentonite Erosion: effects on the Long term performance of the engineered Barrier and Radionuclide Transport) and by the Spanish Government under the project NANOBAG (CTM2011-2797).

Seasonal Water Balance Forecasts for Drought Early Warning in Ethiopia

NASA Astrophysics Data System (ADS)

Spirig, Christoph; Bhend, Jonas; Liniger, Mark

2016-04-01

Droughts severely impact Ethiopian agricultural production. Successful early warning for drought conditions in the upcoming harvest season therefore contributes to better managing food shortages arising from adverse climatic conditions. So far, however, meteorological seasonal forecasts have not been used in Ethiopia's national food security early warning system (i.e. the LEAP platform). Here we analyse the forecast quality of seasonal forecasts of total rainfall and of the meteorological water balance as a proxy for plant available water. We analyse forecast skill of June to September rainfall and water balance from dynamical seasonal forecast systems, the ECMWF System4 and EC-EARTH global forecasting systems. Rainfall forecasts outperform forecasts assuming a stationary climate mainly in north-eastern Ethiopia - an area that is particularly vulnerable to droughts. Forecasts of the water balance index seem to be even more skilful and thus more useful than pure rainfall forecasts. The results vary though for different lead times and skill measures employed. We further explore the potential added value of dynamically downscaling the forecasts through several dynamical regional climate models made available through the EU FP7 project EUPORIAS. Preliminary results suggest that dynamically downscaled seasonal forecasts are not significantly better compared with seasonal forecasts from the global models. We conclude that seasonal forecasts of a simple climate index such as the water balance have the potential to benefit drought early warning in Ethiopia, both due to its positive predictive skill and higher usefulness than seasonal mean quantities.

A 3D imaging system for the non-intrusive in-flight measurement of the deformation of an aircraft propeller and a helicopter rotor

NASA Astrophysics Data System (ADS)

Stasicki, Bolesław; Boden, Fritz; Ludwikowski, Krzysztof

2017-02-01

The non-intrusive in-flight deformation measurement and the resulting local pitch of an aircraft propeller or helicopter rotor blade is a demanding task. The idea of an imaging system integrated and rotating with the air-craft propeller has already been presented at the 30th International Congress on High-Speed Imaging and Photonics (ICHSIP30) in 2012. Since then this system has been designed, constructed and tested in the laboratory as well as in-flight on the Cobra VUT100 of Evektor Aerotechnik, Kunovice (CZ). The major aim of the EU FP7 project AIM2 ("Advanced In-flight Measurement techniques 2" - contract No. 266107) was to ascertain the feasibility of this technique under extreme conditions - vibration and large centrifugal forces - to real flight testing. Based on the gained experience a new rotating system for the application on helicopter rotors has recently been constructed and tested on the whirl tower of Airbus Helicopters, Donauwoerth (D). In this paper the principle of the applied Image Pattern Correlation Technique (IPCT), a specialized type of Digital Image Correlation (DIC), is outlined and the construction of both rotating 3D image acquisition systems dedicated to the in-flight deformation measurement of the aircraft propeller and helicopter rotor are described. Furthermore, the results of the ground and in-flight tests of these systems will be shown and discussed. The obtained results will be helpful for manufacturers in the design of their future aircrafts.

Performance of Magnetic-Superconductor Non-Contact Harmonic Drive for Cryogenic Space Applications: Speed, Torque and Efficiency Measurements

NASA Astrophysics Data System (ADS)

Perez-Diaz, Jose Luis; Diez-Jimenez, Efren; Valiente-Blanco, Ignacio; Cristache, Cristian; Alvarez-Valenzuela, Marco-Antonio; Sanchez-Garcia-Casarrubios, Juan

2015-09-01

Harmonic Drives are widely used in space mainly because of their compactness, large reduction ratio ad zero backlash. However, their use in extreme environments like in cryogenic temperatures is still a challenge. Lubrication, lifetime and fatigue are still issues under these conditions.The MAGDRIVE project, funded by the EU Space FP7 was devoted to test a new concept of harmonic drive reducer. By using the magnetic distance force interactions of magnets and ferromagnetic materials, all the conventional mechanical elements of a Harmonic Drives (teeth, flexspline and ball bearings) are substituted by contactless mechanical components (magnetic gear and superconducting magnetic bearings). The absence of contact between any moving parts prevents wear, lubricants are no longer required and the operational life time is greatly increased. As the magnetic transmission is continuous there is no backlash in the reduction. MAG SOAR Company is already providing contactless mechanical components for space applications able to operate in a wide range of temperatures.In this paper the tests results of a -1:20 ratio MAGDRIVE prototype are reported. In these tests successful operation at 40 K and 10-3 Pa was demonstrated for more than 1.5 million input cycles. A maximum torque of 3 Nm and efficiency higher than 75% at 3000 rpm were demonstrated. The maximum tested input speed was 3000 rpm -six times the previous existing record for harmonic drives at cryogenic temperature.

Assessment of a Tsunami Hazard for Mediterranean Coast of Egypt

NASA Astrophysics Data System (ADS)

Zaytsev, Andrey; Babeyko, Andrey; Yalciner, Ahmet; Pelinovsky, Efim

2017-04-01

Analysis of tsunami hazard for Egypt based on historic data and numerical modelling of historic and prognostic events is given. There are 13 historic events for 4000 years, including one instrumental record (1956). Tsunami database includes 12 earthquake tsunamis and 1 event of volcanic origin (Santorini eruption). Tsunami intensity of events (365, 881, 1303, 1870) is estimated as I = 3 led to tsunami wave height more than 6 m. Numerical simulation of some possible scenario of tsunamis of seismic and landslide origin is done with use of NAMI-DANCE software solved the shallow-water equations. The PTHA method (Probabilistic Tsunami Hazard Assessment - Probabilistic assessment of a tsunami hazard) for the Mediterranean Sea developed in (Sorensen M.B., Spada M., Babeyko A., Wiemer S., Grunthal G. Probabilistic tsunami hazard in the Mediterranean Sea. J Geophysical Research, 2012, vol. 117, B01305) is used to evaluate the probability of tsunami occurrence on the Egyptian coast. The synthetic catalogue of prognostic tsunamis of seismic origin with magnitude more than 6.5 includes 84 920 events for 100000 years. For the wave heights more 1 m the curve: exceedance probability - tsunami height can be approximated by exponential Gumbel function with two parameters which are determined for each coastal location in Egypt (totally. 24 points). Prognostic extreme highest events with probability less 10-4 are not satisfied to the Gumbel function (approximately 10 events) and required the special analysis. Acknowledgements: This work was supported EU FP7 ASTARTE Project [603839], and for EP - NS6637.2016.5.

The tsunami-like sea level disturbance in Crotone harbor, Italy, after the Mw6.5 strike-slip earthquake of 17 November 2015 in Lefkada Isl., Ionian Sea, Greece

NASA Astrophysics Data System (ADS)

Novikova, Tatyana; Annunziato, Alessandro; Charalampakis, Marinos; Romano, Fabrizio; Volpe, Manuela; Tonini, Roberto; Gerardinger, Andrea; Papadopoulos, Gerassimos A.

2016-04-01

On 17 November 2015 an Mw6.5 earthquake ruptured offshore Lefkada Isl. in Ionian Sea, Greece, causing two human victims, minor damage and several ground failures including coastal landslides. Fault plane solutions released by CMT/Harvard, NOA and other institutes have indicated that the faulting style was strike-slip right-lateral, which is quite typical for the area, as for example, the Mw6.3 event that occurred on August 14, 2003, in exactly the same fault zone. In spite of the very low tsunami potential commonly associated to this faulting mechanism, a tsunami-like sea level change was recorded after the earthquake by one tide-gauge in the Crotone harbor, Italy. Preliminary tsunami numerical simulations were performed to reproduce the observed signal. The spectral analysis of the synthetic mareograms close to the entrance of the harbor shows the presence of some peaks that could justify the relation between the natural port resonance and the observed wave amplification. Of particular interest is the coupling between the tsunami energy and the natural modes of basin oscillation enhancing tsunami wave amplitude in harbors through resonance, as shown in some historical events in the Mediterranean Sea and elsewhere. This research is a contribution to the EU-FP7 tsunami research project ASTARTE (Assessment, Strategy And Risk Reduction for Tsunamis in Europe), grant agreement no: 603839, 2013-10-30.

Ab initio theory of spin-orbit coupling for quantum bits in diamond exhibiting dynamic Jahn-Teller effect

NASA Astrophysics Data System (ADS)

Gali, Adam; Thiering, Gergő

Dopants in solids are promising candidates for implementations of quantum bits for quantum computing. In particular, the high-spin negatively charged nitrogen-vacancy defect (NV) in diamond has become a leading contender in solid-state quantum information processing. The initialization and readout of the spin is based on the spin-selective decay of the photo-excited electron to the ground state which is mediated by spin-orbit coupling between excited states states and phonons. Generally, the spin-orbit coupling plays a crucial role in the optical spinpolarization and readout of NV quantum bit (qubit) and alike. Strong electron-phonon coupling in dynamic Jahn-Teller (DJT) systems can substantially influence the effective strength of spin-orbit coupling. Here we show by ab initio supercell density functional theory (DFT) calculations that the intrinsic spin-orbit coupling is strongly damped by DJT effect in the triplet excited state that has a consequence on the rate of non-radiative decay. This theory is applied to the ground state of silicon-vacancy (SiV) and germanium-vacancy (GeV) centers in their negatively charged state that can also act like qubits. We show that the intrinsic spin-orbit coupling in SiV and GeV centers is in the 100 GHz region, in contrast to the NV center of 10 GHz region. Our results provide deep insight in the nature of SiV and GeV qubits in diamond. EU FP7 DIADEMS project (Contract No. 611143).

Past missions - the best way to train future planetary researchers

NASA Astrophysics Data System (ADS)

Kozlova, Natalia; Solodovnikova, Anastasiya; Zubarev, Anatoly; Garov, Andrey; Patraty, Vyacheslav; Kokhanov, Alexander; Karachevtseva, Irina; Nadezhdina, Irina; Konopikhin, Anatoly; Oberst, Juergen

2015-04-01

Practice shows that it is much more interesting and useful to learn from real examples than on imaginary tasks from exercise books. The more technologies and software improves and develops, the more information and new products can be obtained from new processing of archive information collected by past planetary missions. So at MIIGAiK we carry out modern processing of lunar panoramic images obtained by Soviet Lunokhod missions (1970-1973). During two years of the study, which is a part of PRoViDE project (http://www.provide-space.eu/), many students, PhD students, young scientists, as well as professors have taken part in this research. Processing of the data obtained so long ago requires development of specific methods, techniques, special software and extraordinary approach. All these points help to interest young people in planetary science and develop their skills as researchers. Another advantage of data from previous missions is that you can compare your results with the ones obtained during the mission. This also helps to test the developed techniques and software on real data and adjust them for implementation in future missions. The work on Lunokhod data processing became the basis of master and PhD theses of MIIGAiK students and scientists at MExLab. Acknowledgments: The research leading to these results has received funding from the European Community's Seventh Framework Programme (FP7/2007-2013) under grant agreement No 312377 PRoViDE.

Reliable nanomaterial classification of powders using the volume-specific surface area method

NASA Astrophysics Data System (ADS)

Wohlleben, Wendel; Mielke, Johannes; Bianchin, Alvise; Ghanem, Antoine; Freiberger, Harald; Rauscher, Hubert; Gemeinert, Marion; Hodoroaba, Vasile-Dan

2017-02-01

The volume-specific surface area (VSSA) of a particulate material is one of two apparently very different metrics recommended by the European Commission for a definition of "nanomaterial" for regulatory purposes: specifically, the VSSA metric may classify nanomaterials and non-nanomaterials differently than the median size in number metrics, depending on the chemical composition, size, polydispersity, shape, porosity, and aggregation of the particles in the powder. Here we evaluate the extent of agreement between classification by electron microscopy (EM) and classification by VSSA on a large set of diverse particulate substances that represent all the anticipated challenges except mixtures of different substances. EM and VSSA are determined in multiple labs to assess also the level of reproducibility. Based on the results obtained on highly characterized benchmark materials from the NanoDefine EU FP7 project, we derive a tiered screening strategy for the purpose of implementing the definition of nanomaterials. We finally apply the screening strategy to further industrial materials, which were classified correctly and left only borderline cases for EM. On platelet-shaped nanomaterials, VSSA is essential to prevent false-negative classification by EM. On porous materials, approaches involving extended adsorption isotherms prevent false positive classification by VSSA. We find no false negatives by VSSA, neither in Tier 1 nor in Tier 2, despite real-world industrial polydispersity and diverse composition, shape, and coatings. The VSSA screening strategy is recommended for inclusion in a technical guidance for the implementation of the definition.

Effects of Dehydration on Cricket Specific Skill Performance in Hot and Humid Conditions.

PubMed

Gamage, Janaka P; De Silva, Angela P; Nalliah, Arjan K; Galloway, Stuart D R

2016-12-01

The aim of the current study was to assess the effects of dehydration on cricket specific motor skill performance among fast-bowlers, fielders, and batsmen playing in a hot and humid environment. 10 fast-bowlers, 12 fielders and 8 batsmen participated in two field trials conducted 7 days apart: a fluid provision trial (FP) and a fluid restriction trial (FR). Each trial consisted of a 2-hr standardized training session and pretraining and posttraining skill performance assessments. Bowling speed and accuracy (line and length), throwing speed and accuracy (overarm, sidearm and underarm) and timed running between wickets (1, 2, and 3 runs) was assessed pre to posttraining in each trial. Mass loss was 0.6 ± 0.3 kg (0.9 ± 0.5%) in FP, and 2.6 ± 0.5kg (3.7 ± 0.8%) in FR trials. Maintaining mass within 1% of initial values did not cause any significant skill performance decline. However, the dehydration on the FR trial induced a significant time and trial effect for bowling speed by 1.0 ± 0.8% reduction (0.3 ± 0.8% reduction in FP trial; p < .01) and 19.8 ± 17.3% reduction in bowling accuracy for line (3.6 ± 14.2% reduction in FP trial; p < .01), but no effect on bowling length. A significant decline was noted in the FR trial for throwing speed for overarm (6.6 ± 4.1%; p < .01; 1.6 ± 3.4% reduction in FP trial) and sidearm (4.1 ± 2.3%; p < .01; 0.6 ± 4.7% increase in FP trial) techniques, and for throwing accuracy for overarm (14.2 ± 16.3%; p < .01; 0.8 ± 24.2% increase in FP trial) and sidearm (22.3 ± 13.3%; p < .05; 3.2 ± 34.9% reduction in FP trial) techniques. Batsmen demonstrated significant performance drop in making three runs (0.8 ± 1.2% increase in time in FP trial and 2.2 ± 1.7% increase in time in FR trial; p < .01). Moderate-severe dehydration of 3.7% body mass loss significantly impairs motor skill performance among cricketers, particularly bowlers and fielders, playing in hot and humid conditions. Fluid ingestion strategies maintaining mass loss within 1% prevented a decline in skill performance.

Day-to-day management of EU projects: Implementation of a local manager network to secure knowledge transfer

NASA Astrophysics Data System (ADS)

Hoffmann, Friederike; Meyer, Stefanie; de Vareilles, Mahaut

2017-04-01

In the past years there has been a strong push in Norway for increasing participation in the EU Framework Programmes for Research and Innovation. EU projects coordinated by the University of Bergen (UiB) usually receive management support from the central administration (mostly financial) in collaboration with a full- or part-time scientific project manager working on a fixed-term contract at the same institute as the project's principal scientist. With an increasing amount of granted EU projects, the number of scientific project managers employed across the whole university has also increased, and a need for coordination and professionalization of this service became obvious. Until recently, UiB had no unified structures and routines for training of newly recruited project managers, or for archiving and transferring routines and skills after the end of the project and the manager's employment contract. To overcome this administrative knowledge gap, the "Forum for scientific EU project managers at UiB" was founded in spring 2016 as an informal communication platform. Its purpose is to bring together current and previous scientific EU project managers from different disciplines to share their experiences. The main aim of the forum is to transfer and improve knowledge, skills and routines on effective management of EU funded projects, but also to function as a discussion forum where issues arising from handling international consortia can be reviewed. The group meets monthly and discusses current challenges from on-going EU projects as well as routines for specific project operation tasks. These routines are archived in an online best-practise guide which the group currently develops. The regular personal meetings are supplemented with an intense communication via a group mailing list and several individual mail- and phone-meetings. Since lessons learned during project implementation may improve future proposals, UiB research advisors for proposal support frequently interact with the members of the forum. The forum is also used to spread relevant information received from other sources. We already realize that the forum and its products lead to increased competence of scientific EU project managers and research advisors at UiB. To further harvest these synergy effects, we aim to increase our interaction with similar groups, networks, and online platforms in and beyond Europe.

Benefits of family planning: an assessment of women's knowledge in rural Western Kenya.

PubMed

Mutombo, Namuunda; Bakibinga, Pauline; Mukiira, Carol; Kamande, Eva

2014-03-18

The last two decades have seen an increase in literature reporting an increase in knowledge and use of contraceptives among individuals and couples in Kenya, as in the rest of Africa, but there is a dearth of information regarding knowledge about benefits of family planning (FP) in Kenya. To assess the factors associated with knowledge about the benefits of FP for women and children, among women in rural Western Kenya. Data are drawn from the Packard Western Kenya Project Baseline Survey, which collected data from rural women (aged 15-49 years). Ordinal regression was used on 923 women to determine levels of knowledge and associated factors regarding benefits of FP. Women in rural Western Kenya have low levels of knowledge about benefits of FP and are more knowledgeable about benefits for the mother rather than for the child. Only age, spousal communication and type of contraceptive method used are significant. Women's level of knowledge about benefits of FP is quite low and may be one of the reasons why fertility is still high in Western Kenya. Therefore, FP programmes need to focus on increasing women's knowledge about the benefits of FP in this region.

A healthy turn in urban climate change policies; European city workshop proposes health indicators as policy integrators.

PubMed

Keune, Hans; Ludlow, David; van den Hazel, Peter; Randall, Scott; Bartonova, Alena

2012-06-28

The EU FP6 HENVINET project reviewed the potential relevance of a focus on climate change related health effects for climate change policies at the city region level. This was undertaken by means of a workshop with both scientists, city representatives from several EU-countries, representatives of EU city networks and EU-experts. In this paper we introduce some important health related climate change issues, and discuss the current city policies of the participating cities. The workshop used a backcasting format to analyse the future relevance of a health perspective, and the main benefits and challenges this would bring to urban policy making. It was concluded that health issues have an important function as indicators of success for urban climate change policies, given the extent to which climate change policies contribute to public health and as such to quality of life. Simultaneously the health perspective may function as a policy integrator in that it can combine several related policy objectives, such as environmental policies, health policies, urban planning and economic development policies, in one framework for action. Furthermore, the participants to the workshop considered public health to be of strategic importance in organizing public support for climate change policies. One important conclusion of the workshop was the view that the connection of science and policy at the city level is inadequate, and that the integration of scientific knowledge on climate change related health effects and local policy practice is in need of more attention. In conclusion, the workshop was viewed as a constructive advance in the process of integration which hopefully will lead to ongoing cooperation. The workshop had the ambition to bring together a diversity of actor perspectives for exchange of knowledge and experiences, and joint understanding as a basis for future cooperation. Next to the complementarities in experience and knowledge, the mutual critical reflection was a bonus, as ideas had the opportunity to be scrutinized by others, leading to more robustness and common ground. The structured backcasting approach was helpful in integrating all of this with one common focus, embracing diversity and complexity, and stimulating reflection and new ideas.

A healthy turn in urban climate change policies; European city workshop proposes health indicators as policy integrators

PubMed Central

2012-01-01

Background The EU FP6 HENVINET project reviewed the potential relevance of a focus on climate change related health effects for climate change policies at the city region level. This was undertaken by means of a workshop with both scientists, city representatives from several EU-countries, representatives of EU city networks and EU-experts. In this paper we introduce some important health related climate change issues, and discuss the current city policies of the participating cities. Methods The workshop used a backcasting format to analyse the future relevance of a health perspective, and the main benefits and challenges this would bring to urban policy making. Results It was concluded that health issues have an important function as indicators of success for urban climate change policies, given the extent to which climate change policies contribute to public health and as such to quality of life. Simultaneously the health perspective may function as a policy integrator in that it can combine several related policy objectives, such as environmental policies, health policies, urban planning and economic development policies, in one framework for action. Furthermore, the participants to the workshop considered public health to be of strategic importance in organizing public support for climate change policies. One important conclusion of the workshop was the view that the connection of science and policy at the city level is inadequate, and that the integration of scientific knowledge on climate change related health effects and local policy practice is in need of more attention. In conclusion, the workshop was viewed as a constructive advance in the process of integration which hopefully will lead to ongoing cooperation. Conclusions The workshop had the ambition to bring together a diversity of actor perspectives for exchange of knowledge and experiences, and joint understanding as a basis for future cooperation. Next to the complementarities in experience and knowledge, the mutual critical reflection was a bonus, as ideas had the opportunity to be scrutinized by others, leading to more robustness and common ground. The structured backcasting approach was helpful in integrating all of this with one common focus, embracing diversity and complexity, and stimulating reflection and new ideas. PMID:22759496

Dietary flavonoids from modified apple reduce inflammation markers and modulate gut microbiota in mice.

PubMed

Espley, Richard V; Butts, Christine A; Laing, William A; Martell, Sheridan; Smith, Hannah; McGhie, Tony K; Zhang, Jingli; Paturi, Gunaranjan; Hedderley, Duncan; Bovy, Arnaud; Schouten, Henk J; Putterill, Joanna; Allan, Andrew C; Hellens, Roger P

2014-02-01

Apples are rich in polyphenols, which provide antioxidant properties, mediation of cellular processes such as inflammation, and modulation of gut microbiota. In this study we compared genetically engineered apples with increased flavonoids [myeloblastis transcription factor 10 (MYB10)] with nontransformed apples from the same genotype, "Royal Gala" (RG), and a control diet with no apple. Compared with the RG diet, the MYB10 diet contained elevated concentrations of the flavonoid subclasses anthocyanins, flavanol monomers (epicatechin) and oligomers (procyanidin B2), and flavonols (quercetin glycosides), but other plant secondary metabolites were largely unaltered. We used these apples to investigate the effects of dietary flavonoids on inflammation and gut microbiota in 2 mouse feeding trials. In trial 1, male mice were fed a control diet or diets supplemented with 20% MYB10 apple flesh and peel (MYB-FP) or RG apple flesh and peel (RG-FP) for 7 d. In trial 2, male mice were fed MYB-FP or RG-FP diets or diets supplemented with 20% MYB10 apple flesh or RG apple flesh for 7 or 21 d. In trial 1, the transcription levels of inflammation-linked genes in mice showed decreases of >2-fold for interleukin-2 receptor (Il2rb), chemokine receptor 2 (Ccr2), chemokine ligand 10 (Cxcl10), and chemokine receptor 10 (Ccr10) at 7 d for the MYB-FP diet compared with the RG-FP diet (P < 0.05). In trial 2, the inflammation marker prostaglandin E(2) (PGE(2)) in the plasma of mice fed the MYB-FP diet at 21 d was reduced by 10-fold (P < 0.01) compared with the RG-FP diet. In colonic microbiota, the number of total bacteria for mice fed the MYB-FP diet was 6% higher than for mice fed the control diet at 21 d (P = 0.01). In summary, high-flavonoid apple was associated with decreases in some inflammation markers and changes in gut microbiota when fed to healthy mice.

Enterobacterial repetitive intergenic consensus sequences and the PCR to generate fingerprints of genomic DNAs from Vibrio cholerae O1, O139, and non-O1 strains.

PubMed

Rivera, I G; Chowdhury, M A; Huq, A; Jacobs, D; Martins, M T; Colwell, R R

1995-08-01

Enterobacterial repetitive intergenic consensus (ERIC) sequence polymorphism was studied in Vibrio Cholerae strains isolated before and after the cholera epidemic in Brazil (in 1991), along with epidemic strains from Peru, Mexico, and India, by PCR. A total of 17 fingerprint patterns (FPs) were detected in the V. cholerae strains examined; 96.7% of the toxigenic V. cholerae O1 strains and 100% of the O139 serogroup strains were found to belong to the same FP group comprising four fragments (FP1). The nontoxigenic V. cholerae O1 also yielded four fragments but constituted a different FP group (FP2). A total of 15 different patterns were observed among the V. cholerae non-O1 strains. Two patterns were observed most frequently for V. cholerae non-01 strains, 25% of which have FP3, with five fragments, and 16.7% of which have FP4, with two fragments. Three fragments, 1.75, 0.79, and 0.5 kb, were found to be common to both toxigenic and nontoxigenic V. cholerae O1 strains as well as to group FP3, containing V. cholerae non-O1 strains. Two fragments of group FP3, 1.3 and 1.0 kb, were present in FP1 and FP2 respectively. The 0.5-kb fragment was common to all strains and serogroups of V. cholerae analyzed. It is concluded from the results of this study, based on DNA FPs of environmental isolates, that it is possible to detect an emerging virulent strain in a cholera-endemic region. ERIC-PCR constitutes a powerful tool for determination of the virulence potential of V. cholerae O1 strains isolated in surveillance programs and for molecular epidemiological investigations.

Validation of the CME Geomagnetic Forecast Alerts Under the COMESEP Alert System

NASA Astrophysics Data System (ADS)

Dumbović, Mateja; Srivastava, Nandita; Rao, Yamini K.; Vršnak, Bojan; Devos, Andy; Rodriguez, Luciano

2017-08-01

Under the European Union 7th Framework Programme (EU FP7) project Coronal Mass Ejections and Solar Energetic Particles (COMESEP, http://comesep.aeronomy.be), an automated space weather alert system has been developed to forecast solar energetic particles (SEP) and coronal mass ejection (CME) risk levels at Earth. The COMESEP alert system uses the automated detection tool called Computer Aided CME Tracking (CACTus) to detect potentially threatening CMEs, a drag-based model (DBM) to predict their arrival, and a CME geoeffectiveness tool (CGFT) to predict their geomagnetic impact. Whenever CACTus detects a halo or partial halo CME and issues an alert, the DBM calculates its arrival time at Earth and the CGFT calculates its geomagnetic risk level. The geomagnetic risk level is calculated based on an estimation of the CME arrival probability and its likely geoeffectiveness, as well as an estimate of the geomagnetic storm duration. We present the evaluation of the CME risk level forecast with the COMESEP alert system based on a study of geoeffective CMEs observed during 2014. The validation of the forecast tool is made by comparing the forecasts with observations. In addition, we test the success rate of the automatic forecasts (without human intervention) against the forecasts with human intervention using advanced versions of the DBM and CGFT (independent tools available at the Hvar Observatory website, http://oh.geof.unizg.hr). The results indicate that the success rate of the forecast in its current form is unacceptably low for a realistic operation system. Human intervention improves the forecast, but the false-alarm rate remains unacceptably high. We discuss these results and their implications for possible improvement of the COMESEP alert system.

The development of a vulnerabilities indicator library for coastal flood risk management at a European scale

NASA Astrophysics Data System (ADS)

Owen, Damon; Viavattene, Christophe; Priest, Sally; Micou, Paula; Parker, Dennis

2015-04-01

Recent and historic low-frequency, high-impact events (Xynthia, Ligurian Flash Floods, the 1953 North Sea storm surge etc) have demonstrated the flood risks faced by exposed coastal areas in Europe. The hazard probability is likely to increase due to a changing climate with more frequent and violent instances of surge-driven floods, wind damage, erosion, overtopping and rain-driven flash flooding. The number and value of receptors in the coastal area also increases due to continued economic development and population growth. As part of the FP7 EU RISCKIT (Resilience-Increasing Strategies for Coasts toolkit) project, a coastal vulnerability indicator library has been produced incorporating ecosystems, built environment, human population, critical infrastructure and the overall characteristics of the coastal system. The library will include data at European, national and local levels and will be gathered, in large part, through a multitude of interviews with various members of the coastal community at 11 case study sites across Europe. The presentation will give a brief outline of the challenges in developing vulnerability indicators - particularly for countries where specific data is limited or lacking - and how the library will be organised to facilitate the use of the data. Finally, the presentation will describe how the vulnerability library will feed into a Coastal Risk Assessment Framework (CRAF). The CRAF will evaluate coastal risk at regional scale and identify "hot spots" to assist coastal practitioners to choose the best prevention, mitigation and preparedness measures for their coast. The work described in this abstract was supported by the European Community's 7th Framework Programme through the grant to the budget of RISC-KIT, contract no. 603458, and by contributions by the partner institutes.

Submarine slope instability offshore western Calabria, Italy: possible triggering of tsunamigenic landslides by seismic load

NASA Astrophysics Data System (ADS)

Ausilia Paparo, Maria; Armigliato, Alberto; Pagnoni, Gianluca; Zaniboni, Filippo; Gallotti, Glauco; Tinti, Stefano

2017-04-01

The Eastern Tyrrhenian margin offshore western Calabria (Italy) has experienced several mass movements involving varying volumes and shapes, as revealed by several geological surveys identifying slide scars and massive deposits. The hypothesis that at least some of these mass movements was tsunamigenic sounds perfectly reasonable. In this study, we focus on the continental edge offshore the Santa Eufemia Gulf and the Paola Basin, because the area experienced several strong earthquakes (Mw up to 7), some of them in the last centuries (see, for example, the 1905 earthquake and the late shocks of the 1783 sequence). Our aim is to study the seismic load as the trigger mechanism of mass failures: not all earthquakes generate tsunamis, but the conjunction of definite factors as seafloor shaking and pore water pressure could temporarily reduce soil shear stress, inducing failures and submarine tsunamigenic landslides. We have selected several sections of the Calabrian margin with different gradients and studied their slope stability by using the Minimum Lithostatic Deviation (MLD) method. We have applied typical Peak Ground Accelerations (PGAs) obtained from local historical earthquakes by means of regression laws, determining the potentially unstable sectors, as well as the volumes of the material that can be set in motion. This in turn can be used as input for future tsunami modelling and hazard assessment. This work is a contribution to assess local hazard and risk in western Calabrian coast where earthquakes can trigger tsunamigenic submarine mass movements: the impact and the effects of such phenomena could be disastrous for coastal infrastructures and populations without the proper mitigation measures. This work was carried out in the frame of the EU Project called ASTARTE - Assessment, STrategy And Risk Reduction for Tsunamis in Europe (Grant 603839, 7th FP, ENV.2013.6.4-3).

Regulatory ecotoxicity testing of nanomaterials - proposed modifications of OECD test guidelines based on laboratory experience with silver and titanium dioxide nanoparticles.

PubMed

Hund-Rinke, Kerstin; Baun, Anders; Cupi, Denisa; Fernandes, Teresa F; Handy, Richard; Kinross, John H; Navas, José M; Peijnenburg, Willie; Schlich, Karsten; Shaw, Benjamin J; Scott-Fordsmand, Janeck J

2016-12-01

Regulatory ecotoxicity testing of chemicals is of societal importance and a large effort is undertaken at the OECD to ensure that OECD test guidelines (TGs) for nanomaterials (NMs) are available. Significant progress to support the adaptation of selected TGs to NMs was achieved in the context of the project MARINA ( http://www.marina-fp7.eu/ ) funded within the 7th European Framework Program. Eight OECD TGs were adapted based on the testing of at least one ion-releasing NM (Ag) and two inert NMs (TiO 2 ). With the materials applied, two main variants of NMs (ion releasing vs. inert NMs) were addressed. As the modifications of the test guidelines refer to general test topics (e.g. test duration or measuring principle), we assume that the described approaches and modifications will be suitable for the testing of further NMs with other chemical compositions. Firm proposals for modification of protocols with scientific justification(s) are presented for the following tests: growth inhibition using the green algae Raphidocelis subcapitata (formerly: Pseudokirchneriella subcapitata; TG 201), acute toxicity with the crustacean Daphnia magna (TG 202), development toxicity with the fish Danio rerio (TG 210), reproduction of the sediment-living worm Lumbriculus variegatus (TG 225), activity of soil microflora (TGs 216, 217), and reproduction of the invertebrates (Enchytraeus crypticus, Eisenia fetida, TGs 220, 222). Additionally, test descriptions for two further test systems (root elongation of plants in hydroponic culture; test on fish cells) are presented. Ecotoxicological data obtained with the modified test guidelines for TiO 2 NMs and Ag NM and detailed method descriptions are available.

The Fast-spectrum Transmutation Experimental Facility FASTEF: Main design achievements (part 2: Reactor building design and plant layout) within the FP7-CDT collaborative project of the European Commission

DOE Office of Scientific and Technical Information (OSTI.GOV)

De Bruyn, D.; Engelen, J.; Ortega, A.

MYRRHA (Multi-purpose hybrid Research Reactor for High-tech Applications) is the flexible experimental accelerator-driven system (ADS) in development at SCK-CEN in replacement of its material testing reactor BR2. SCK-CEN in association with 17 European partners from industry, research centres and academia, responded to the FP7 (Seventh Framework Programme) call from the European Commission to establish a Central Design Team (CDT) for the design of a Fast Spectrum Transmutation Experimental Facility (FASTEF) able to demonstrate efficient transmutation and associated technology through a system working in subcritical and/or critical mode. The project has started on April 01, 2009 for a period of threemore » years. In this paper, we present the latest concept of the reactor building and the plant layout. The FASTEF facility has evolved quite a lot since the intermediate reporting done at the ICAPP'10 and ICAPP'11 conferences 1,2. Many iterations have been performed to take into account the safety requirements. The present configuration enables an easy operation and maintenance of the facility, including the possibility to change large components of the reactor. In a companion paper 3, we present the latest configuration of the reactor core and primary system. (authors)« less

APhoRISM FP7 project: the Multi-platform volcanic Ash Cloud Estimation (MACE) infrastructure

NASA Astrophysics Data System (ADS)

Merucci, Luca; Corradini, Stefano; Bignami, Christian; Stramondo, Salvatore

2014-05-01

APHORISM is an FP7 project that aims to develop innovative products to support the management and mitigation of the volcanic and the seismic crisis. Satellite and ground measurements will be managed in a novel manner to provide new and improved products in terms of accuracy and quality of information. The Multi-platform volcanic Ash Cloud Estimation (MACE) infrastructure will exploit the complementarity between geostationary, and polar satellite sensors and ground measurements to improve the ash detection and retrieval and to fully characterize the volcanic ash clouds from source to the atmosphere. The basic idea behind the proposed method consists to manage in a novel manner, the volcanic ash retrievals at the space-time scale of typical geostationary observations using both the polar satellite estimations and in-situ measurements. The typical ash thermal infrared (TIR) retrieval will be integrated by using a wider spectral range from visible (VIS) to microwave (MW) and the ash detection will be extended also in case of cloudy atmosphere or steam plumes. All the MACE ash products will be tested on three recent eruptions representative of different eruption styles in different clear or cloudy atmospheric conditions: Eyjafjallajokull (Iceland) 2010, Grimsvotn (Iceland) 2011 and Etna (Italy) 2011-2012. The MACE infrastructure will be suitable to be implemented in the next generation of ESA Sentinels satellite missions.

Setting the Stage for Harmonized Risk Assessment by Seismic Hazard Harmonization in Europe (SHARE)

NASA Astrophysics Data System (ADS)

Woessner, Jochen; Giardini, Domenico; SHARE Consortium

2010-05-01

Probabilistic seismic hazard assessment (PSHA) is arguably one of the most useful products that seismology can offer to society. PSHA characterizes the best available knowledge on the seismic hazard of a study area, ideally taking into account all sources of uncertainty. Results form the baseline for informed decision making, such as building codes or insurance rates and provide essential input to each risk assessment application. Several large scale national and international projects have recently been launched aimed at improving and harmonizing PSHA standards around the globe. SHARE (www.share-eu.org) is the European Commission funded project in the Framework Programme 7 (FP-7) that will create an updated, living seismic hazard model for the Euro-Mediterranean region. SHARE is a regional component of the Global Earthquake Model (GEM, www.globalquakemodel.org), a public/private partnership initiated and approved by the Global Science Forum of the OECD-GSF. GEM aims to be the uniform, independent and open access standard to calculate and communicate earthquake hazard and risk worldwide. SHARE itself will deliver measurable progress in all steps leading to a harmonized assessment of seismic hazard - in the definition of engineering requirements, in the collection of input data, in procedures for hazard assessment, and in engineering applications. SHARE scientists will create a unified framework and computational infrastructure for seismic hazard assessment and produce an integrated European probabilistic seismic hazard assessment (PSHA) model and specific scenario based modeling tools. The results will deliver long-lasting structural impact in areas of societal and economic relevance, they will serve as reference for the Eurocode 8 (EC8) application, and will provide homogeneous input for the correct seismic safety assessment for critical industry, such as the energy infrastructures and the re-insurance sector. SHARE will cover the whole European territory, the Maghreb countries in the Southern Mediterranean and Turkey in the Eastern Mediterranean. By strongly including the seismic engineering community, the project maintains a direct connection to the Eurocode 8 applications and the definition of the Nationally Determined Parameters, through the participation of the CEN/TC250/SC8 committee in the definition of the output specification requirements and in the hazard validation. SHARE will thus produce direct outputs for risk assessment. With this contribution, we focus on providing an overview of the goals and current achievement of the project.

European cancer mortality predictions for the year 2014.

PubMed

Malvezzi, M; Bertuccio, P; Levi, F; La Vecchia, C; Negri, E

2014-08-01

From most recent available data, we projected cancer mortality statistics for 2014, for the European Union (EU) and its six more populous countries. Specific attention was given to pancreatic cancer, the only major neoplasm showing unfavorable trends in both sexes. Population and death certification data from stomach, colorectum, pancreas, lung, breast, uterus, prostate, leukemias and total cancers were obtained from the World Health Organisation database and Eurostat. Figures were derived for the EU, France, Germany, Italy, Poland, Spain and the UK. Projected 2014 numbers of deaths by age group were obtained by linear regression on estimated numbers of deaths over the most recent time period identified by a joinpoint regression model. In the EU in 2014, 1,323,600 deaths from cancer are predicted (742,500 men and 581,100 women), corresponding to standardized death rates of 138.1/100,000 men and 84.7/100,000 women, falling by 7% and 5%, respectively, since 2009. In men, predicted rates for the three major cancers (lung, colorectum and prostate cancer) are lower than in 2009, falling by 8%, 4% and 10%, respectively. In women, breast and colorectal cancers had favorable trends (-9% and -7%), but female lung cancer rates are predicted to rise 8%. Pancreatic cancer is the only neoplasm with a negative outlook in both sexes. Only in the young (25-49 years), EU trends become more favorable in men, while women keep registering slight predicted rises. Cancer mortality predictions for 2014 confirm the overall favorable cancer mortality trend in the EU, translating to an overall 26% fall in men since its peak in 1988, and 20% in women, and the avoidance of over 250,000 deaths in 2014 compared with the peak rate. Notable exceptions are female lung cancer and pancreatic cancer in both sexes. © The Author 2014. Published by Oxford University Press on behalf of the European Society for Medical Oncology. All rights reserved. For permissions, please email: journals.permissions@oup.com.

Testing chemical carcinogenicity by using a transcriptomics HepaRG-based model?

PubMed Central

Doktorova, T. Y.; Yildirimman, Reha; Ceelen, Liesbeth; Vilardell, Mireia; Vanhaecke, Tamara; Vinken, Mathieu; Ates, Gamze; Heymans, Anja; Gmuender, Hans; Bort, Roque; Corvi, Raffaella; Phrakonkham, Pascal; Li, Ruoya; Mouchet, Nicolas; Chesne, Christophe; van Delft, Joost; Kleinjans, Jos; Castell, Jose; Herwig, Ralf; Rogiers, Vera

2014-01-01

The EU FP6 project carcinoGENOMICS explored the combination of toxicogenomics and in vitro cell culture models for identifying organotypical genotoxic- and non-genotoxic carcinogen-specific gene signatures. Here the performance of its gene classifier, derived from exposure of metabolically competent human HepaRG cells to prototypical non-carcinogens (10 compounds) and hepatocarcinogens (20 compounds), is reported. Analysis of the data at the gene and the pathway level by using independent biostatistical approaches showed a distinct separation of genotoxic from non-genotoxic hepatocarcinogens and non-carcinogens (up to 88 % correct prediction). The most characteristic pathway responding to genotoxic exposure was DNA damage. Interlaboratory reproducibility was assessed by blindly testing of three compounds, from the set of 30 compounds, by three independent laboratories. Subsequent classification of these compounds resulted in correct prediction of the genotoxicants. As expected, results on the non-genotoxic carcinogens and the non-carcinogens were less predictive. In conclusion, the combination of transcriptomics with the HepaRG in vitro cell model provides a potential weight of evidence approach for the evaluation of the genotoxic potential of chemical substances. PMID:26417288

Physical demands in elite team handball: comparisons between male and female players.

PubMed

Michalsik, L B; Aagaard, P

2015-09-01

The aim of the present study was to examine potential differences in the physical demands imposed on male vs. female adult elite team handball players during match-play. Male and female elite team handball players were monitored over a six and five season time span, respectively. Each player was evaluated during match-play by use of video recording and subsequent computerized locomotive and technical match analysis. Furthermore, physiological measurements during match-play, physical testing and anthropometric measurements were performed. Female players (FP, N.=82) covered a longer mean total distance per match (4693±333 m, group means±SD) compared to male players (MP, N.=83, 3945±538 m) when playing full time (P<0.01). FP exercised at a greater relative workload (79.4% of VO2-max) than MP (70.9% of VO2-max, P<0.05), but performed less high-intense running per match (2.5% of total distance covered) than MP (7.9%, P<0.01). FP also spent less time standing still (10.8% of total effective playing time) compared to MP (36.9%, P<0.001) and showed fewer activity changes (663.8±99.7) compared to MP (1482.4±312.6, P<0.001). MP received more tackles in total in offence (34.5±21.3) and performed more tackles in total in defence (29.9±12.3) compared to FP (14.6±9.2, 20.7±9.7, P<0.05). Furthermore, MP performed more high-intense technical playing actions per match (36.9±13.1) than FP (28.3±11.0, P<0.05). The mean body height and body mass differed between MP (189.6±5.8 cm, 91.7±7.5 kg) and FP (175.4±6.1 cm, 69.5±6.5 kg, P<0.001). Substantial gender-specific differences in the physical demands in elite team handball were observed, with MP performing more high-intense, strength-related playing actions and high-intensity running than FP. Conversely, FP covered a greater total distance and demonstrated a higher relative workload than MP. The physical training of male and female elite team handball players should be designed to reflect these contrasting needs.

Space-Data Routers: Advanced data routing protocols for enhancing data exploitation for space weather applications

NASA Astrophysics Data System (ADS)

Anastasiadis, Anastasios; Daglis, Ioannis A.; Balasis, George; Papadimitriou, Constantinos; Tsaoussidis, Vassilios; Diamantopoulos, Sotirios

2014-05-01

Data sharing and access are major issues in space sciences, as they influence the degree of data exploitation. The availability of multi-spacecraft distributed observation methods and adaptive mission architectures require computationally intensive analysis methods. Moreover, accurate space weather forecasting and future space exploration far from Earth will be in need of real-time data distribution and assimilation technologies. The FP7-Space collaborative research project "Space-Data Routers" (SDR) relies on space internetworking and in particular on Delay Tolerant Networking (DTN), which marks the new era in space communications. SDR unifies space and earth communication infrastructures and delivers a set of tools and protocols for space-data exploitation. The main goal is to allow space agencies, academic institutes and research centers to share space-data generated by single or multiple missions, in an efficient, secure and automated manner. Here we are presenting the architecture and basic functionality of a DTN-based application specifically designed in the framework of the SDR project, for data query, retrieval and administration that will enable addressing outstanding science questions related to space weather, through the provision of simultaneous real-time data sampling at multiple points in space. The work leading to this paper has received funding from the European Union's Seventh Framework Programme (FP7-SPACE-2010-1) under grant agreement no. 263330 for the SDR (Space-Data Routers for Exploiting Space Data) collaborative research project. This paper reflects only the authors' views and the Union is not liable for any use that may be made of the information contained therein.

Direct excitation luminescence spectroscopy of Eu(III) complexes of 1,4,7-tris(carbamoylmethyl)-1,4,7,10- tetraazacyclododecane derivatives and kinetic studies of their catalytic cleavage of an RNA analog.

PubMed

Nwe, Kido; Richard, John P; Morrow, Janet R

2007-11-28

The macrocycles 1,4,7-tris(carbamoylmethyl)-1,4,7,10-tetrazacyclododecane (1), 1,4,7-tris[(N-ethyl)carbamoylmethyl]-1,4,7,10-tetraazacyclododecane (2), 1,4,7-tris[(N,N-diethyl)carbamoylmethyl]-1,4,7,10-tetraazacyclododecane (3) and their Eu(III) complexes are prepared. Studies using direct Eu(III) excitation luminescence spectroscopy show that all three Eu(III) complexes exhibit only one predominant isomer with two bound waters under neutral to mildly basic conditions (Eu(X)(H(2)O)(2) for X = 1-3). There are no detectable ligand ionizations over the pH range 5.0-8.0 for Eu(3), 5.0-8.5 for Eu(2) or 5.0-9.5 for Eu(1). The three Eu(III) complexes show a linear dependence of second-order rate constants for the cleavage of 4-nitrophenyl-2-hydroxyethylphosphate (HpPNP) on pH in the range 6.5-8.0 for Eu(3), 7.0-8.5 for Eu(2) and 7.0-9.0 for Eu(1). This pH-rate profile is consistent with the Eu(III) complex-substrate complex being converted to the active form by loss of a proton and with Eu(III) water pK(a) values that are higher than 8.0 for Eu(3), 8.5 for Eu(2) and 9.0 for Eu(1). Inhibition studies show that Eu() binds strongly to the dianionic ligand methylphosphate (K(d) = 0.28 mM), and more weakly to diethylphosphate (K(d) = 7.5 mM), consistent with a catalytic role of the Eu(III) complexes in stabilizing the developing negative charge on the phosphorane transition state.

TRANSVAC research infrastructure - Results and lessons learned from the European network of vaccine research and development.

PubMed

Geels, Mark J; Thøgersen, Regitze L; Guzman, Carlos A; Ho, Mei Mei; Verreck, Frank; Collin, Nicolas; Robertson, James S; McConkey, Samuel J; Kaufmann, Stefan H E; Leroy, Odile

2015-10-05

TRANSVAC was a collaborative infrastructure project aimed at enhancing European translational vaccine research and training. The objective of this four year project (2009-2013), funded under the European Commission's (EC) seventh framework programme (FP7), was to support European collaboration in the vaccine field, principally through the provision of transnational access (TNA) to critical vaccine research and development (R&D) infrastructures, as well as by improving and harmonising the services provided by these infrastructures through joint research activities (JRA). The project successfully provided all available services to advance 29 projects and, through engaging all vaccine stakeholders, successfully laid down the blueprint for the implementation of a permanent research infrastructure for early vaccine R&D in Europe. Copyright © 2015. Published by Elsevier Ltd.

Hybrid coconut seedlings, scholarships, and discount cards for family planning acceptors.

PubMed

Sumarsono

1989-10-01

Having learned from failed family planning (FP) incentive schemes in other countries, Indonesia implemented a reward system designed to popularize FP in the community. In order to overcome cultural opposition to FP, many countries in the 1970s opted to give incentives--money, materials, etc.--to new contraceptive acceptors and the FP workers who successfully recruited them. These countries, which oftentimes spent up to 1/4 of their program budget on incentives, saw rapid increases in the number of new acceptors. The results, however, only reflected a superficial acceptance of FP. When the incentives stopped, the number of acceptors dropped considerably. Recognizing this, the Indonesian government set out to increase FP acceptance by making the small family the norm in the community. And one of the approaches for doing so was a reward system. The goals of the reward program were: 1) to raise awareness of the recognition given to individuals or groups that have accepted FP; 2) to create pride among FP workers and new acceptors; and 3) to generate leadership in the community. Villages with high FP acceptance receive rewards such as deep-wells that provide clean water or income generating projects. Individuals also receive rewards that sometimes include hybrid coconut seedlings which, after 3 years, can yield up to 700 coconuts, which can provide a family with a significant supplemental income. The government also gives scholarships to children of FP acceptors. Also, the president of Indonesia publicly recognized family planning acceptors. In 1989, over 800,000 couples received awards for practicing contraception over the past 5-16 years.

Multichannel Luminescence Properties of Mixed-Valent Eu2+/Eu3+ Coactivated SrAl3BO7 Nanocrystalline Phosphors for Near-UV LEDs.

PubMed

Liu, Xiaoming; Xie, Weijie; Lü, Ying; Feng, Jingchun; Tang, Xinghua; Lin, Jun; Dai, Yuhua; Xie, Yu; Yan, Liushui

2017-11-20

Up to now, orchestrating the coexistence of Eu 2+ and Eu 3+ activators in a single host lattice has been an extremely difficult task, especially for the appearance of the characteristic emission of Eu 2+ and Eu 3+ in order to generate white light. Nevertheless, here we demonstrate a new Eu 2+ /Eu 3+ coactivated SrAl 3 BO 7 nanocrystalline phosphor with abundant and excellent multichannel luminescence properties. A series of Eu 2+ /Eu 3+ coactivated SrAl 3 BO 7 nanocrystalline phosphors were prepared through a Pechini-type sol-gel method followed by a reduction process. With excitation of UV/NUV light, the prepared SrAl 3 BO 7 :Eu 2+ ,Eu 3+ phosphors show not only the characteristic f-f transitions of Eu 3+ ion ( 5 D J → 7 F J,J' , J, J' = 0-3), but also the 5d → 4f transitions of Eu 2+ ion with comparable intensity from 400 to 700 nm in the whole visible spectral region. The luminescence color of the SrAl 3 BO 7 :Eu 2+ ,Eu 3+ phosphor can be tuned from blue, blue-green, white, and orange to orange-red by changing the excitation wavelength, the overall doping concentration of europium ions (Eu 2+ , Eu 3+ ), and the relative ratio of Eu 2+ to Eu 3+ ions to some extent. A single-phase white-light emission has been realized in SrAl 3 BO 7 :Eu 2+ ,Eu 3+ phosphor. The obtained SrAl 3 BO 7 :Eu 2+ ,Eu 3+ phosphor has potential application in the area of NUV white-light-emitting diodes.

General Design Memorandum, Gulfport Harbor, Mississippi. Design Memorandum Number 1. Appendix F. Regional Impact and Financial Analysis

DTIC Science & Technology

1990-03-01

District, Mobile AREA A ORK UNIT NUMBCRS Economic Analysis Sec., Planning Div. (CESAM-PD-FE) P. 0. Box 2288, Mobile , AL 36628-0001 11. CONTROLLING OPPICE...NAME AND ADDRESS It. REPORT DATE US Army Engineer District, Mobile March 1990 Plan Development Sec., Planning Div. (CESAM-PD-FP) IS. NUMBER OF PAGES P...0. Box 2288, Mobile , AL 36628-0001 114 14. MONITORING AGENCY NAMIE & AOORIESSQif EU110nt km cIOfi.IAd 011*e) VS. SECURITY CLASS. (of Wol roport

Case descriptions of fibropapillomatosis in rehabilitating loggerhead sea turtles Caretta caretta in the southeastern USA.

PubMed

Page-Karjian, Annie; Norton, Terry M; Harms, Craig; Mader, Doug; Herbst, Larry H; Stedman, Nancy; Gottdenker, Nicole L

2015-08-20

Fibropapillomatosis (FP) is a debilitating neoplastic disease that affects all species of hard-shelled sea turtles, including loggerhead turtles Caretta caretta. FP can represent an important clinical concern in rehabilitating turtles, since managing these infectious lesions often requires special husbandry provisions including quarantine, and FP may affect clinical progression, extend rehabilitation duration, and complicate prognoses. Here we describe cases of rehabilitating loggerhead turtles with FP (designated FP+). Medical records of FP+ loggerhead cases from 3 sea turtle rehabilitation facilities in the southeastern USA were reviewed. Between 2001 and 2014, FP was observed in 8 of 818 rehabilitating loggerhead turtles (0.98% overall prevalence in admitted patients). FP+ loggerhead size classes represented were large juvenile (straight carapace length, SCL: 58.1-80 cm; n=7) and adult (SCL>87 cm; n=1). Three turtles presented with FP, and 5 developed tumors during rehabilitation within a range of 45 to 319 d. Sites of new tumor growth included the eyes, sites of trauma, neck, and glottis. FP+ turtles were scored as mildly (3/8), moderately (4/8), or heavily (1/8) afflicted. The mean total time in rehabilitation was 476±355 d (SD) (range: 52-1159 d). Six turtles were released without visible evidence of FP, 1 turtle was released with mild FP, and 1 turtle with internal FP was euthanized. Clinical decision-making for FP+ loggerhead patients can be aided by such information as time to tumor development, anatomic locations to monitor for new tumor growth, husbandry considerations, diagnostic and treatment options, and comparisons to FP in rehabilitating green turtles Chelonia mydas.

SOAP based web services and their future role in VO projects

NASA Astrophysics Data System (ADS)

Topf, F.; Jacquey, C.; Génot, V.; Cecconi, B.; André, N.; Zhang, T. L.; Kallio, E.; Lammer, H.; Facsko, G.; Stöckler, R.; Khodachenko, M.

2011-10-01

Modern state-of-the-art web services are from crucial importance for the interoperability of different VO tools existing in the planetary community. SOAP based web services assure the interconnectability between different data sources and tools by providing a common protocol for communication. This paper will point out a best practice approach with the Automated Multi-Dataset Analysis Tool (AMDA) developed by CDPP, Toulouse and the provision of VEX/MAG data from a remote database located at IWF, Graz. Furthermore a new FP7 project IMPEx will be introduced with a potential usage example of AMDA web services in conjunction with simulation models.

"India Population Projects" in Karnataka.

PubMed

Reddy, P H; Badari, V S

1991-12-01

An overview, objectives, implementation, and research and evaluation studies of 2 India Population Projects in Karnataka are presented. The India Population Project I (IPP-I) was conducted in Karnataka and Uttar Pradesh. India Population Project III (IPP-III) took place between 1984-92 in 6 districts of Karnataka: Belgaum, Bijapur, Dharwad, Bidar, Gulbarga, and Raichur, and 4 districts in Kerala. The 6 districts in Karnataka accounted for 36% (13.2 million) of the total national population. The project cost was Rs. 713.1 million which was shared by the World Bank, and the Indian national and regional government. Due to poor past performance, these projects were undertaken to improve health and family welfare status. Specific project objectives are outlined. IPP-I included an urban component, and optimal Government of India program, and an intensive rural initiative. The urban program aimed to improved pre- and postnatal services and facilities, and the family planning (FP) in Bangalore city. The rural program was primarily to provide auxiliary nurse-midwives and hospitals and clinics, and also supplemental feeding program for pregnant and nursing mothers and children up to 2 years. The government program provided FP staff and facilities. IPP-I had 3 units to oversee building construction, to recruit staff and provide supplies and equipment, and to establish a Population Center. IPP-III was concerned with service delivery; information, education, and communication efforts (IEC) and population education; research and evaluation; and project management. Both projects contributed significantly to improving the infrastructure. A brief account of the types and kinds of studies undertaken is given. Studies were grouped into longitudinal studies of fertility, mortality, and FP; management information and evaluation systems for health and family welfare programs; experimental strategies; and other studies. Research and evaluation studies in IPP-III encompassed studies in gaps in knowledge, skills, and practice of health and FP personnel; baseline and endline surveys; and operational evaluation of the management information and evaluation system; factors affecting primary health care in Gulbarga district; evaluation of radio health lessons and the impact of the Kalyana Matha Program; and studies of vaccination and child survival and maternal mortality. Training programs were also undertaken.

What has happened in about the last 20 years in the Canyoles watershed?

NASA Astrophysics Data System (ADS)

Ángel González Peñaloza, Félix; Cerdà, Artemi; Díaz del Olmo, Fernando

2013-04-01

Along history, the Mediterranean arid lands have undergone widespread land use transformation, especially in recent decades (Piqueras, 2012). There are changes driven by socio-economic conditions, such as European Agricultural Policies (MacDonald et al., 2000; Keenleyside and Tucker, 2010; Renwick et al., 2013), which have caused land degradation processes (soil erosion, soil sealing, water pollution, salinization, wildfires, land abandonment, urban sprawl and intensive agricultural practices). Land degradation is the results of a complex Socio Ecological System (SES) which should be addressed using the Geographical Information System (GIS) to identify and assess the spatial variation of land use change. Therefore, the aim of this work has been to describe and assess the land use change by human activities in a typical Mediterranean watershed (Cànyoles Valley) located at South-East of Iberian Peninsula as a part of the Land Ecosystem and Degradation Desertification Response Assessment (LEDDRA) project, which has undergone a quick land use change in last two decades (1986 - 2005). Results reveal that the surface area devoted to rainfed crops (e.g., olive crops (47 %) and vineyards (28 %) and forestry have decline significantly; while the citrus orchards (irrigated crops) and unproductive areas (e.g., roads and railways, urban areas) have been increasing its surface in just about last 20 years in 45 % and 67 %, respectively. According to the literature review (Cerdà, 1994; Cerdá et al., 1999, 2007; Cerdà, 2007; Bodí et al., 2012; González-Peñaloza, 2012) these recent changes, in the study site, have caused many environmental disturbances mainly due to the lack control strategies plans of land degradation. Acknowledgements This research is being conducted by the EU project "Land Ecosystem and Degradation Desertification: Assessing the Fit of Responses" LEDDRA 243857 CONSORTIUM AGREEMENT. TR07 - VII PROGRAMA MARCO - ENERGÍA FP7-ENERGY-2007-2-TREN. - European Union FP7. ENV.2009 243857. Keywords: GIS, land use, degradation, Cànyoles valley, agricultural practices. References Bodí, M.B., Cerdà, A., Mataix-Solera, J., Doerr, S.H. 2012. Efectos de los incendios forestales en la vegetación y el suelo en la cuenca mediterránea: revisión bibliográfica. Boletín de la Asociación de Geógrafos Españoles 58, 33-35 Cerdà, A, Giménez - Morera, A. Terol, E., Domínguez, A. Jurgensen, M.F., Doerr, S.H. 1999. Cultivos de cítricos y erosión de suelos en el este de la Península Ibérica. En Control de la Degradación de los suelos y cambio global (Eds: Sánchez Díaz, J., Asins Velis, S.). IV Simposio sobre control de la degradación de los suelos y cambio global. Universitat de València. Valencia. 71 - 72. Cerdà, A. 1994. Arroyada superficial en terrazas de cultivo abandonadas. El caso del País Valenciano. Cuadernos de Geografía 56, 135-154 Cerdá, A. 2007. Soil water erosion on road embankments in Eastern Spain. Science of the Total Environments 378, 151-155. González-Peñaloza, F.A., Cerdà, Zavala, L.M., Jordán, A. 2012. Do conservative agriculture practices increase soil water repellency? A case study in citrus-cropped soils. Soil & Tillage Research 124, 233 - 239. Keenleyside, C., Tucker, G.M. 2010. Farmland Abandonment in the EU: An assessment of Trend and Prospects. Report Prepared for WWF. Institute for European Environmental Policy, London. 93 pp. MacDonald, D., Crabtree, J.R., Wiesinger, G., Dax, T., Stamou, N., Fleury, P., Gutiérrez-Lazpita, J., Gibon, A. 2000. Agricultural abandonment in mountain areas of Europe: Environmental consequenses and policy reponse. Journal of Environmental Management 59, 47-69. Piqueras, J. 2012. Geografía del Territorio Valenciano. Departament de Geografia, Universitat de València (Valencia, España). 256 pp. Renwick, A., Jansson, T., Verburg, P.H., Revoredo-Giha, C., Britz, W., Gocht, A., McCracken, D. 2013. Policy reforms and agricultural land abandonment in the EU. Land Use Policy 30, 446-457.

Investigating FP Tau’s protoplanetary disk structure through modeling

NASA Astrophysics Data System (ADS)

Brinjikji, Marah; Espaillat, Catherine

2017-01-01

This project presents a study aiming to understand the structure of the protoplanetary disk around FP Tau, a very young, very low mass star in the Taurus star-forming region. We have gathered existing optical, Spitzer, Herschel and submillimeter observations to construct the spectral energy distribution (SED) of FP Tau. We have used the D’Alessio et al (2006) physically self-consistent irradiated accretion disk model including dust settling to model the disk of FP Tau. Using this method, the best fit for the SED of FP Tau is a model that includes a gap located 10-20 AU away from the star. This gap is filled with optically thin dust that separates the optically thick dust in the outer disk from the optically thick dust in the inner disk. These characteristics indicate that FP Tau’s protostellar system is best classified as a pre-transitional disk. Near-infrared interferometry in the K-Band from Willson et al 2016 indicates that FP Tau has a small gap located 10-20 AU from the star, which is consistent with the model we produced, lending further support to the pre-transitional disk interpretation. The most likely explanation for the existence of a gap in the disk is a forming planet.

Materials Data on EuH32C8N4Cl7 (SG:18) by Materials Project

DOE Data Explorer

Kristin Persson

2016-04-22

Computed materials data using density functional theory calculations. These calculations determine the electronic structure of bulk materials by solving approximations to the Schrodinger equation. For more information, see https://materialsproject.org/docs/calculations

Climate information for the wind energy industry in the Mediterranean Region

NASA Astrophysics Data System (ADS)

Calmanti, Sandro; Davis, Melanie; Schmidt, Peter; Dell'Aquila, Alessandro

2013-04-01

According to the World Wind Energy Association the total wind generation capacity worldwide has come close to cover 3% of the world's electricity demand in 2011. Thanks to the enormous resource potential and the relatively low costs of construction and maintenance of wind power plants, the wind energy sector will remain one of the most attractive renewable energy investment options. Studies reveal that climate variability and change pose a new challenge to the entire renewable energy sector, and in particular for wind energy. Stakeholders in the wind energy sector mainly use, if available, site-specific historical climate information to assess wind resources at a given project site. So far, this is the only source of information that investors (e.g., banks) are keen to accept for decisions concerning the financing of wind energy projects. However, one possible wind energy risk at the seasonal scale is the volatility of earnings from year to year investment. The most significant risk is therefore that not enough units of energy (or megawatt hours) can be generated from the project to capture energy sales to pay down debt in any given quarter or year. On the longer time scale the risk is that a project's energy yields fall short of their estimated levels, resulting in revenues that consistently come in below their projection, over the life of the project. The nature of the risk exposure determines considerable interest in wind scenarios, as a potential component of both the planning and operational phase of a renewable energy project. Fundamentally, by using climate projections, the assumption of stationary wind regimes can be compared to other scenarios where large scale changes in atmospheric circulation patterns may affect local wind regimes. In the framework of CLIM-RUN EU FP7 project, climate experts are exploring the potential of seasonal to decadal climate forecast techniques (time-frame 2012-2040) and regional climate scenarios (time horizon 2040+) over the Mediterranean Region as a tool for assessing the impact of changes in climate patterns on the energy output of wind power plants. Subsequently, we will give here a brief overview of these techniques as well as first results related to wind projections for different sites across the Mediterranean Region. We will highlight that regional climate models have a large potential for enhancing the quality of climate projections in the presence of complex orography and in the proximity of coastal areas.

Key site abandonment steps in CO2 storage

NASA Astrophysics Data System (ADS)

Kühn, M.; Wipki, M.; Durucan, S.; Deflandre, J.-P.; Lüth, S.; Wollenweber, J.; Chadwick, A.; Böhm, G.

2012-04-01

CO2CARE is an EU funded project within FP7-research, which started in January 2011 with a funding period of three years. The project objectives will be achieved through an international consortium consisting of 23 partners from Europe, USA, Canada, Japan, and Australia, belonging to universities, research institutes, and energy companies. According to the EC Guidance Document 3, the lifetime of a CO2 storage site can be generally subdivided into 6 phases: 1. assessment, 2. characterisation, 3. development, 4. operation, 5. post-closure/pre-transfer, and 6. post transfer. CO2CARE deals with phases 5 and 6. The main goals of the project are closely linked to the three high-level requirements of the EU Directive 2009/31/EC, Article 18 for CO2 storage which are: (i) absence of any detectable leakage, (ii) conformity of actual behaviour of the injected CO2 with the modelled behaviour, and (iii) the storage site is evolving towards a situation of long-term stability. These criteria have to be fulfilled prior to subsequent transfer of responsibility to the competent authorities, typically 20 or 30 years after site closure. CO2CARE aims to formulate robust procedures for site abandonment which will meet the regulatory requirements and ensure long-term integrity of the storage complex. We present key results from the first year of the project via a report on international regulatory requirements on CO2 geological storage and site abandonment that includes a general overview on the current state-of-the art in abandonment methodologies in the oil and gas industry worldwide. Due to the long time-frames involved in CO2 storage (in the range of several thousands of years), the behaviour of a system with respect to, for example, long-term well stability can be demonstrated only by using long-term predictive modelling tools to study potential leakage pathways. Trapping mechanisms for CO2 are of high interest concerning a quantitative estimation of physically captured, capillary bound, dissolved, and precipitated CO2 in form of specific mineral phases. Useful results, partly supported by laboratory and field experiments, can be gained by process simulations considering periods of hundreds or thousands of years. Risk management for the post-operational phases is another essential part of the workflow. A first version of a decision support system has been created by means of a number of high-level and low-level criteria, most of which had to be defined in advance. The system provides instructions for the operators on how to act in case of irregularities after site closure. A compilation of all relevant results will be available at the end of the project in form of best practice guidelines. However, dissemination of information about the latest results and developments in the field of site abandonment are given via the CO2CARE-website (www.co2care.org) and also in conferences, workshops or radio and TV interviews.

Antibiotic-producing Pseudomonas fluorescens mediates rhizome rot disease resistance and promotes plant growth in turmeric plants.

PubMed

Prabhukarthikeyan, S R; Keerthana, U; Raguchander, T

2018-05-01

Rhizome rot of turmeric caused by Pythium aphanidermatum is a major threat to turmeric-cultivating areas of India. This study intends to evaluate the performance of fluorescent pseudomonads against Rhizome rot disease and understand the resistance mechanism in Turmeric plants. Fluorescent pseudomonads were screened against Pythium aphanidermatum using dual culture. Selected strains were evaluated for the performance of growth promoting attributes and the presence of antibiotic genes through PCR analysis. Strain FP7 recorded the maximum percent inhibition of P. aphanidermatum under in vitro conditions. Strains FP7 and TPF54 both increased plant growth in turmeric plants in vitro. Strain FP7 alone contained all the evaluated antibiotic biosynthetic genes. Talc and liquid-based formulations were prepared with effective strain and tested for its biocontrol activities under both glasshouse and field conditions. Enzymatic activities of the induced defense enzymes such as PO, PPO, PAL, CAT and SOD were estimated and subjected to spectrophotometric analysis. A combination of rhizome dip and soil drench of FP7 liquid formulation treatment remarkably recorded the minimum disease incidence, higher defense enzymes, maximum plant growth and yield under glasshouse and field conditions. Application of strain FP7 increased the defense molecules, plant growth and yield in turmeric plants thereby reducing the incidence of rhizome rot disease. Moreover, this study has a potential to be adopted for sustainable and eco-friendly turmeric production. Copyright © 2018 Elsevier GmbH. All rights reserved.

ESMN in Memoriam (1998 -- 2006)

NASA Astrophysics Data System (ADS)

Rutten, R. J.

2007-05-01

The EC-FP5 European Solar Magnetism Network (ESMN) was terminated during this conference. Together with its FP4 predecessor, the European Solar Magnetometry Network (ESMN), it funded 22 postdoc and 9 graduate-student appointments at nine solar physics groups in Western Europe, it enhanced Europe-wide collaboration in solar physics, and it contributed to the integration of East-European groups in West-European enterprises. Its unfortunate demise results from lack of further fortune in the FP6 lottery. The FP6-funded Utrecht-Stockholm-Oslo graduate school in solar physics represents offspring, the FP6 Solaire network is a partial replacement, and the EAST undertaking and pledge to build an EST is a most worthy FP7 stake. The EC's policy shifts from postdoc to predoc funding and from requiring (too) small to requiring (too) large consortia are criticized.

Fluoropyrimidines plus cisplatin versus gemcitabine/gemcitabine plus cisplatin in locally advanced and metastatic biliary tract carcinoma - a retrospective study.

PubMed

Croitoru, Adina; Gramaticu, Iulia; Dinu, Ioana; Gheorghe, Liana; Alexandrescu, Sorin; Buica, Florina; Luca, Ioana; Becheanu, Gabriel; Herlea, Vlad; Simionov, Iulia; Hrehoret, Doina; Lupescu, Ioana; Popescu, Irinel; Diculescu, Mircea

2012-09-01

This is a retrospective study of patients with advanced biliary tract carcinoma (BTC), who were treated with different regimens of chemotherapy. We studied patients with advanced BTC registered at the Department of Oncology at the Fundeni Clinical Institute between 2004 and 2008. The following data were analyzed: rate of response, progression free survival (PFS) to first and second line of chemotherapy, overall survival (OS) and drug toxicity. Ninety-six patients were eligible having either advanced intra or extrahepatic cholangiocarcinoma, or gallbladder cancer with no prior chemotherapy. Out of 96 patients, 57 (59.4%) received fluoropyrimidines (FP)+cisplatin and 39 (40.6%) gemcitabine (Gem)+/-cisplatin. The median PFS for FP+cisplatin was 5.9 months (95%CI 5-6.9) and for Gem+/-cisplatin 6.3 months (95%CI 5.4-7.1), p=0.661. Median OS for FP+cisplatin was 10.3 months (95%CI 7.5-13.1) and for Gem+/-cisplatin 9.1 months (95%CI 7.0-11.2), p=0.098. On disease progression, 46 patients received second line CT (Gem or FP+/-platinum compounds). Median OS for patients with FP based first line and Gem+/-cisplatin in second line was 19 months (95%CI 8.9-29) higher than for the reverse sequence: 13.2 months (95%CI 12-14.4), but not statistically significant (p=0.830). All patients were evaluated for toxicities. Most patients (75.5%) reported at least one adverse event. Our results through direct comparison of FP+cisplatin with Gem+/-cisplatin as first line treatment did not show any statistical differences in terms of rate of response, PFS and OS. However, our study showed that FP+cisplatin as first line and Gem based second line therapy gave a better OS rate.

One-shot calculation of temperature-dependent optical spectra and phonon-induced band-gap renormalization

NASA Astrophysics Data System (ADS)

Zacharias, Marios; Giustino, Feliciano

Electron-phonon interactions are of fundamental importance in the study of the optical properties of solids at finite temperatures. Here we present a new first-principles computational technique based on the Williams-Lax theory for performing predictive calculations of the optical spectra, including quantum zero-point renormalization and indirect absorption. The calculation of the Williams-Lax optical spectra is computationally challenging, as it involves the sampling over all possible nuclear quantum states. We develop an efficient computational strategy for performing ''one-shot'' finite-temperature calculations. These require only a single optimal configuration of the atomic positions. We demonstrate our methodology for the case of Si, C, and GaAs, yielding absorption coefficients in good agreement with experiment. This work opens the way for systematic calculations of optical spectra at finite temperature. This work was supported by the UK EPSRC (EP/J009857/1 and EP/M020517/) and the Leverhulme Trust (RL-2012-001), and the Graphene Flagship (EU-FP7-604391).

Family planning in Guinea: a need for better public commitment.

PubMed

Delamou, Alexandre; Koivogui, Akoi; Dubourg, Dominique; Delvaux, Thérèse

2014-01-01

To describe the evolution of family planning (FP) in Guinea and to identify strengths, weaknesses, opportunities and threats of the current FP programme. Descriptive study of the evolution of FP in Guinea between 1992 and 2010. First, national laws as well as health policies and strategic plans related to reproductive health and family planning were reviewed. Second, FP indicators were extracted from the Guinean Demographic and Health Surveys (1992, 1999 and 2005). Third, FP services, sources of supply and data on FP funding were analysed. Laws, policies and strategic plans in Guinea are supportive of FP programme and services. Public and private actors are not sufficiently coordinated. The general government expenditure on health has remained stable at 6-7% between 2005 and 2011 despite a doubling of total expenditures on health, and contraceptives are supplied by foreign aid. Modern contraceptive prevalence slightly increased from 1.5% in 1992 to 6.8% in 2005 among women aged 15-49. A stronger national engagement in favour of repositioning FP should result in improved government funding of the FP programme and the promotion of long-acting and permanent methods. © 2013 John Wiley & Sons Ltd.

Glycopyrronium once-daily significantly improves lung function and health status when combined with salmeterol/fluticasone in patients with COPD: the GLISTEN study—a randomised controlled trial

PubMed Central

Frith, Peter A; Thompson, Philip J; Ratnavadivel, Rajeev; Chang, Catherina L; Bremner, Peter; Day, Peter; Frenzel, Christina; Kurstjens, Nicol

2015-01-01

Background The optimal use of various therapeutic combinations for moderate/severe chronic obstructive pulmonary disease (COPD) is unclear. The GLISTEN trial compared the efficacy of two long-acting anti-muscarinic antagonists (LAMA), when combined with an inhaled corticosteroid (ICS) and a long-acting β2 agonist (LABA). Methods This randomised, blinded, placebo-controlled trial in moderate/severe COPD patients compared once-daily glycopyrronium (GLY) 50 µg, once-daily tiotropium (TIO) 18 µg or placebo (PLA), when combined with salmeterol/fluticasone propionate (SAL/FP) 50/500 µg twice daily. The primary objective was to determine the non-inferiority of GLY+SAL/FP versus TIO+SAL/FP on trough FEV1 after 12 weeks. An important secondary objective was whether addition of GLY to SAL/FP was better than SAL/FP alone. Results 773 patients (mean FEV1 57.2% predicted) were randomised; 84.9% completed the trial. At week 12, GLY+SAL/FP demonstrated non-inferiority to TIO+SAL/FP for trough FEV1: least square mean treatment difference (LSMdiff) −7 mL (SE 17.4) with a lower limit for non-inferiority of −60 mL. There was significant increase in week 12 trough FEV1 with GLY+SAL/FP versus PLA+SAL/FP (LSMdiff 101 mL, p<0.001). At 12 weeks, GLY+SAL/FP produced significant improvement in St George's Respiratory Questionnaire total score versus PLA+SAL/FP (LSMdiff −2.154, p=0.02). GLY+SAL/FP demonstrated significant rescue medication reduction versus PLA+SAL/FP (LSMdiff −0.72 puffs/day, p<0.001). Serious adverse events were similar for GLY+SAL/FP, TIO+SAL/FP and PLA+SAL/FP with an incidence of 5.8%, 8.5% and 5.8%, respectively. Conclusions GLY+SAL/FP showed comparable improvements in lung function, health status and rescue medication to TIO+SAL/FP. Importantly, addition of GLY to SAL/FP demonstrated significant improvements in lung function, health status and rescue medication compared to SAL/FP. Trial registration number NCT01513460. PMID:25841237

Inhibitory effects and underlying mechanism of 7-hydroxyflavone phosphate ester in HeLa cells.

PubMed

Zhang, Ting; Du, Jiang; Liu, Liguo; Chen, Xiaolan; Yang, Fang; Jin, Qi

2012-01-01

Chrysin and its phosphate ester have previously been shown to inhibit cell proliferation and induce apoptosis in Hela cells; however, the underlying mechanism remains to be characterized. In the present study, we therefore synthesized diethyl flavon-7-yl phosphate (FP, C(19)H(19)O(6)P) by a simplified Atheron-Todd reaction, and explored its anti-tumor characteristics and mechanisms. Cell proliferation, cell cycle progression and apoptosis were measured by MTS, flow cytometry and terminal deoxynucleotidyl transferase dUTP nick end labeling techniques, respectively in human cervical cancer HeLa cells treated with 7-hydroxyflavone (HF) and FP. p21, proliferating cell nuclear antigen (PCNA) and cAMP levels in Hela cells were analyzed by western blot and radioimmunoassay. Both HF and FP inhibited proliferation and induced apoptosis in HeLa cells via induction of PCNA/p21 expression, cleaved caspase-3/poly (ADP-ribose) polymerase (PARP)-1, elevation of cAMP levels, and cell cycle arrest with accumulation of cells in the G0/G1 fraction. The effects of FP were more potent than those of HF. The interactions of FP with Ca(2+)-calmodulin (CaM) and Ca(2+)-CaM-phosphodiesterase (PDE)1 were explored by electrospray ionization-mass spectrometry and fluorescence spectra. FP, but not HF, formed non-covalent complexes with Ca(2+)-CaM-PDE1, indicating that FP is an inhibitor of PDE1, and resulting in elevated cellular cAMP levels. It is possible that the elevated cAMP levels inhibit growth and induce apoptosis in Hela cells through induction of p21 and cleaved caspase-3/PARP-1 expression, and causing down-regulation of PCNA and cell cycle arrest with accumulation of cells in the G0/G1 and G2/M fractions. In conclusion, FP was shown to be a Ca(2+)-CaM-PDE inhibitor, which might account for its underlying anti-cancer mechanism in HeLa cells. These observations clearly demonstrate the special roles of phosphorylated flavonoids in biological processes, and suggest that FP might represent a potential new drug for the therapy of human cervical carcinoma.

Inhibitory Effects and Underlying Mechanism of 7-Hydroxyflavone Phosphate Ester in HeLa Cells

PubMed Central

Liu, Liguo; Chen, Xiaolan; Yang, Fang; Jin, Qi

2012-01-01

Chrysin and its phosphate ester have previously been shown to inhibit cell proliferation and induce apoptosis in Hela cells; however, the underlying mechanism remains to be characterized. In the present study, we therefore synthesized diethyl flavon-7-yl phosphate (FP, C19H19O6P) by a simplified Atheron-Todd reaction, and explored its anti-tumor characteristics and mechanisms. Cell proliferation, cell cycle progression and apoptosis were measured by MTS, flow cytometry and terminal deoxynucleotidyl transferase dUTP nick end labeling techniques, respectively in human cervical cancer HeLa cells treated with 7-hydroxyflavone (HF) and FP. p21, proliferating cell nuclear antigen (PCNA) and cAMP levels in Hela cells were analyzed by western blot and radioimmunoassay. Both HF and FP inhibited proliferation and induced apoptosis in HeLa cells via induction of PCNA/p21 expression, cleaved caspase-3/poly (ADP-ribose) polymerase (PARP)-1, elevation of cAMP levels, and cell cycle arrest with accumulation of cells in the G0/G1 fraction. The effects of FP were more potent than those of HF. The interactions of FP with Ca2+-calmodulin (CaM) and Ca2+-CaM-phosphodiesterase (PDE)1 were explored by electrospray ionization-mass spectrometry and fluorescence spectra. FP, but not HF, formed non-covalent complexes with Ca2+-CaM-PDE1, indicating that FP is an inhibitor of PDE1, and resulting in elevated cellular cAMP levels. It is possible that the elevated cAMP levels inhibit growth and induce apoptosis in Hela cells through induction of p21 and cleaved caspase-3/PARP-1 expression, and causing down-regulation of PCNA and cell cycle arrest with accumulation of cells in the G0/G1 and G2/M fractions. In conclusion, FP was shown to be a Ca2+-CaM-PDE inhibitor, which might account for its underlying anti-cancer mechanism in HeLa cells. These observations clearly demonstrate the special roles of phosphorylated flavonoids in biological processes, and suggest that FP might represent a potential new drug for the therapy of human cervical carcinoma. PMID:22574207

Europlanet Integrated and Distributed Information Service

NASA Astrophysics Data System (ADS)

Schmidt, W.; Capria, M. T.; Chanteur, G.

2009-04-01

During the past decades the various disciplines in planetary sciences have developed to a very high international standard. But the collaboration between the different fields should be improved. To overcome the current fragmentation of the EU Planetary Science community and thereby to increase the scientific return of the related investment, the EU commission is funding via its Framework Program 7 the development of the "Europlanet Research Infrastructure -Europlanet RI". The Europlanet RI will consolidate the integration of the European Planetary Science community which started with Europlanet's FP6 project and will integrate major parts of the related distributed European infrastructure to be shared, fed and expanded by all planetary scientists. This infrastructure encompasses as diverse components as space exploration, ground-based observations, laboratory experiments and numerical modeling teams. Europlanet RI aims at bringing scientists from Europe and beyond together who are working in these fields, support the exchange of experts and ideas and make as many resources and data as possible available to the research community. A central part of Europlanet RI is the "Integrated and Distributed Information Service" or Europlanet-IDIS. The task of IDIS as central part of Europlanet is to provide an easy-to-use Web-based platform to locate teams and laboratories with special knowledge needed to support the own research activities, give access to the wealth of already available data, initiate new research activities needed to interpret accumulated data or to solve open questions, and to exploit synergies between space-based missions and capabilities of ground based observatories. It also offers to a wide range of teams and laboratories the possibility to share their data, advertise their capabilities and increase the scientific return by cooperation. IDIS is organized as an EU FP7 Support Activity, consisting of different access nodes which are connected by integrated search facilities, compatible structures and a common management. Each of these nodes concentrates on a special field of planetary sciences, has its own team of related international experts and is responsible for the access to information and data centres related to its area of competence. Integrated keyword-based search-possibilities direct inquiries to those node(s), most likely to return the wanted information. These nodes are hosted by the following organizations: - The Finnish Meteorological Institute (FMI) in Helsinki, Finland, hosts the Technical Node for a wide range of support activities and provides the network management. - The Institute of Planetary Research (IPR) of DLR in Berlin, Germany, hosts the Planetary Surfaces and Interiors Node, concentrating on internal structure, formation and evolution of the planets, their moons, asteroids and comets. - The Institut für Weltraumforschung, IWF (Space Research Institute) of the Austrian Academy of Sciences (OeAW) in Graz hosts the Planetary Plasma Node in close cooperation with the French space plasma data center CDPP in Toulouse. - The Institut Pierre-Simon Laplace in Paris hosts the Planetary Atmospheres Node. - The Paris Observatory hosts the Virtual Observatory Paris Data Center providing among others access to a wide range of atomic and molecular spectral databases. - The Istituto di Fisica dello Spazio Interplanetario (IFSI) in Rome hosts the Small Bodies and Dust Node, in cooperation with the ESA/ESTECs Virtual Meteor Observatory in Noordwijk, The Netherlands, concentrating on research and observations related to solar system asteroids, comets, meteors and interplanetary dust. During the next four years a set of tools for describing, accessing and combining information and data from different sources will be developed, offering finally a Virtual Observatory like access to many data essential for planetary research from European and None-European sources. Web access via any of the mentioned nodes, e.g. the Technical Node at http://www.europlanet-idis.fi/

Building and evaluating sensor-based Citizens' Observatories for improving quality of life in cities

NASA Astrophysics Data System (ADS)

Castell, Nuria; Lahoz, William; Schneider, Philipp; Høiskar, Britt Ann; Grossberndt, Sonja; Naderer, Clemens; Robinson, Johanna; Kocman, David; Horvat, Milena; Bartonova, Alena

2014-05-01

Urban air quality, the environmental quality of public spaces and indoor areas such as schools, are areas of great concern to citizens and policymakers. However, access to information addressing these areas is not always available in a user-friendly manner. In particular, the quality and quantity of this information is not consistent across these areas, and does not reflect differences in needs among users. The EU-funded CITI-SENSE project will build on the concept of the Citizens' Observatories to empower citizens to contribute to and participate in environmental governance, and enable them to support and influence decision making by policymakers. To achieve this goal, CITI-SENSE will develop, test, demonstrate and validate a community-based environmental monitoring and information system using low-cost sensors and Earth Observation applications. Key to achieving this goal is the chain "sensors-platforms-products-users" linking providers of technology to users: (i) technologies for distributed monitoring (sensors); (ii) information and communication technologies (platform); (iii) information products and services (products); (iv) and citizen involvement in both monitoring and societal decisions (users). The CITI-SENSE observatories cover three empowerment initiatives: urban air quality; public spaces; and school indoor quality. The empowerment initiatives are being performed at nine locations across Europe. Each location has adapted the generic case study to their local circumstances and has contacted the urban stakeholders needed to run the study. The empowerment initiatives are divided into two phases: a first phase (Pilot Study), and a second phase (Full Implementation). The main goal of the Pilot Study is to test and evaluate the chain "sensors-platform-products-users". To assess the results of the empowerment initiatives, key performance indicators (KPIs) are being developed; these include questionnaires for users. The KPIs will be used to design the full implementation phase of the project. First results from the Pilot Study will be presented for three participating cities: Ljubljana (Slovenia), Vienna (Austria) and Oslo (Norway), which differ in size, environmental conditions and social perception on local air quality. Ljubljana and Oslo empowerment initiatives include urban air quality, and school indoor air quality, while Vienna only includes urban air quality. For the area of urban air quality, the three cities will deploy a wireless network of five static sensor nodes and distribute five personal sensors among people to be carried while performing daily activities in the pilot study. The data will be accessible to users through mobile phones, web services and other devices. For the full implementation phase the sensor network will comprise a total of 20 to 40 static nodes, depending on the size of the city, and 20 personal nodes. For the school indoor air quality three sensors will be allocated inside the school and one outside. The data will be visible provided in school classrooms giving the students a unique and innovative approach to learn about air quality by being involved. Acknowledgements: CITI-SENSE is a Collaborative Project partly funded by the EU FP7-ENV-2012 under grant agreement no 308524. www.citi-sense.eu.

The IS-ENES climate4impact portal: bridging the CMIP5 and CORDEX data to impact users

NASA Astrophysics Data System (ADS)

Som de Cerff, Wim; Plieger, Maarten; Page, Christian; Tatarinova, Natalia; Hutjes, Ronald; de Jong, Fokke; Bärring, Lars; Sjökvist, Elin; Vega Saldarriaga, Manuel; Santiago Cofiño Gonzalez, Antonio

2015-04-01

The aim of climate4impact (climate4impact.eu) is to enhance the use of Climate Research Data and to enhance the interaction with climate effect/impact communities. The portal is based on 17 impact use cases from 5 different European countries, and is evaluated by a user panel consisting of use case owners. It has been developed within the IS-ENES European project and is currently operated and further developed in the IS ENES2 project. As the climate impact community is very broad, the focus is mainly on the scientific impact community. Climate4impact is connected to the Earth System Grid Federation (ESGF) nodes containing global climate model data (GCM data) from the fifth phase of the Coupled Model Intercomparison Project (CMIP5) and regional climate model data (RCM) data from the Coordinated Regional Climate Downscaling Experiment (CORDEX). This global network of climate model data centers offers services for data description, discovery and download. The climate4impact portal connects to these services using OpenID, and offers a user interface for searching, visualizing and downloading global climate model data and more. A challenging task is to describe the available model data and how it can be used. The portal informs users about possible caveats when using climate model data. All impact use cases are described in the documentation section, using highlighted keywords pointing to detailed information in the glossary. Climate4impact currently has two main objectives. The first one is to work on a web interface which automatically generates a graphical user interface on WPS endpoints. The WPS calculates climate indices and subset data using OpenClimateGIS/icclim on data stored in ESGF data nodes. Data is then transmitted from ESGF nodes over secured OpenDAP and becomes available in a new, per user, secured OpenDAP server. The results can then be visualized again using ADAGUC WMS. Dedicated wizards for processing of climate indices will be developed in close collaboration with users. The second one is to expose climate4impact services, so as to offer standardized services which can be used by other portals (like the future Copernicus platform, developed in the EU FP7 CLIPC project). This has the advantage to add interoperability between several portals, as well as to enable the design of specific portals aimed at different impact communities, either thematic or national. In the presentation the following subjects will be detailed: - Lessons learned developing climate4impact.eu - Download: Directly from ESGF nodes and other THREDDS catalogs - Connection with the downscaling portal of the university of Cantabria - Experiences on the question and answer site via Askbot - Visualization: Visualize data from ESGF data nodes using ADAGUC Web Map Services. - Processing: Transform data, subset, export into other formats, and perform climate indices calculations using Web Processing Services implemented by PyWPS, based on NCAR NCPP OpenClimateGIS and IS-ENES2 icclim. - Security: Login using OpenID for access to the ESGF data nodes. The ESGF works in conjunction with several external websites and systems. The climate4impact portal uses X509 based short lived credentials, generated on behalf of the user with a MyProxy service. Single Sign-on (SSO) is used to make these websites and systems work together. - Discovery: Facetted search based on e.g. variable name, model and institute using the ESGF search services. A catalog browser allows for browsing through CMIP5 and any other climate model data catalogues (e.g. ESSENCE, EOBS, UNIDATA).

An end-users oriented methodology for enhancing the integration of knowledge on soil-water-sediment systems in River Basin Management: an illustration from the AquaTerra project.

PubMed

Merly, Corinne; Chapman, Antony; Mouvet, Christophe

2012-01-01

Research results in environmental and socio-economic sciences are often under-used by stakeholders involved in the management of natural resources. To minimise this gap, the FP6 EU interdisciplinary project AquaTerra (AT) developed an end-users' integration methodology in order to ensure that the data, knowledge and tools related to the soil-water-sediment system that were generated by the project were delivered in a meaningful way for end-users, thus improving their uptake. The methodology and examples of its application are presented in this paper. From the 408 project deliverables, 96 key findings were identified, 53 related to data and knowledge, and 43 describing advanced tools. River Basin Management (RBM) stakeholders workshops identified 8 main RBM issues and 25 specific stakeholders' questions related to RBM which were classified into seven groups of cross-cutting issues, namely scale, climate change, non-climatic change, the need for systemic approaches, communication and participation, international and inter-basin coordination and collaboration, and the implementation of the Water Framework Directive. The integration methodology enabled an assessment of how AT key findings meet stakeholders' demands, and for each main RBM issue and for each specific question, described the added-value of the AT project in terms of knowledge and tools generated, key parameters to consider, and recommendations that can be made to stakeholders and the wider scientific community. Added value and limitations of the integration methodology and its outcomes are discussed and recommendations are provided to further improve integration methodology and bridge the gaps between scientific research data and their potential uptake by end-users.

PlanetServer/EarthServer: Big Data analytics in Planetary Science

NASA Astrophysics Data System (ADS)

Pio Rossi, Angelo; Oosthoek, Jelmer; Baumann, Peter; Beccati, Alan; Cantini, Federico; Misev, Dimitar; Orosei, Roberto; Flahaut, Jessica; Campalani, Piero; Unnithan, Vikram

2014-05-01

Planetary data are freely available on PDS/PSA archives and alike (e.g. Heather et al., 2013). Their exploitation by the community is somewhat limited by the variable availability of calibrated/higher level datasets. An additional complexity of these multi-experiment, multi-mission datasets is related to the heterogeneity of data themselves, rather than their volume. Orbital - so far - data are best suited for an inclusion in array databases (Baumann et al., 1994). Most lander- or rover-based remote sensing experiment (and possibly, in-situ as well) are suitable for similar approaches, although the complexity of coordinate reference systems (CRS) is higher in the latter case. PlanetServer, the Planetary Service of the EC FP7 e-infrastructure project EarthServer (http://earthserver.eu) is a state-of-art online data exploration and analysis system based on the Open Geospatial Consortium (OGC) standards for Mars orbital data. It provides access to topographic, panchromatic, multispectral and hyperspectral calibrated data. While its core focus has been on hyperspectral data analysis through the OGC Web Coverage Processing Service (Oosthoek et al., 2013; Rossi et al., 2013), the Service progressively expanded to host also sounding radar data (Cantini et al., this volume). Additionally, both single swath and mosaicked imagery and topographic data are being added to the Service, deriving from the HRSC experiment (e.g. Jaumann et al., 2007; Gwinner et al., 2009) The current Mars-centric focus can be extended to other planetary bodies and most components are general purpose ones, making possible its application to the Moon, Mercury or alike. The Planetary Service of EarthServer is accessible on http://www.planetserver.eu References: Baumann, P. (1994) VLDB J. 4 (3), 401-444, Special Issue on Spatial Database Systems. Cantini, F. et al. (2014) Geophys. Res. Abs., Vol. 16, #EGU2014-3784, this volume Heather, D., et al.(2013) EuroPlanet Sci. Congr. #EPSC2013-626 Gwinner, K., et al., Earth Planet. Sci. Lett., 294, 506-519, doi:10.1016/j.epsl.2009.11.007. Oosthoek, J.H.P, et al. (2013) Advances in Space Research. DOI: 10.1016/j.asr.2013.07.002 Rossi, A. P., et al. (2013) XLDB Workshop Europe, CERN, Switzerland

Spectrum and prevalence of FP/TMEM127 gene mutations in pheochromocytomas and paragangliomas.

PubMed

Yao, Li; Schiavi, Francesca; Cascon, Alberto; Qin, Yuejuan; Inglada-Pérez, Lucia; King, Elizabeth E; Toledo, Rodrigo A; Ercolino, Tonino; Rapizzi, Elena; Ricketts, Christopher J; Mori, Luigi; Giacchè, Mara; Mendola, Antonella; Taschin, Elisa; Boaretto, Francesca; Loli, Paola; Iacobone, Maurizio; Rossi, Gian-Paolo; Biondi, Bernadette; Lima-Junior, José Viana; Kater, Claudio E; Bex, Marie; Vikkula, Miikka; Grossman, Ashley B; Gruber, Stephen B; Barontini, Marta; Persu, Alexandre; Castellano, Maurizio; Toledo, Sergio P A; Maher, Eamonn R; Mannelli, Massimo; Opocher, Giuseppe; Robledo, Mercedes; Dahia, Patricia L M

2010-12-15

Pheochromocytomas and paragangliomas are genetically heterogeneous neural crest-derived neoplasms. We recently identified germline mutations of the novel transmembrane-encoding gene FP/TMEM127 in familial and sporadic pheochromocytomas consistent with a tumor suppressor effect. To examine the prevalence and spectrum of FP/TMEM127 mutations in pheochromocytomas and paragangliomas and to test the effect of mutations in vitro. We sequenced the FP/TMEM127 gene in 990 individuals with pheochromocytomas and/or paragangliomas, including 898 previously unreported cases without mutations in other susceptibility genes from 8 independent worldwide referral centers between January 2009 and June 2010. A multiplex polymerase chain reaction-based method was developed to screen for large gene deletions in 545 of these samples. Confocal microscopy of 5 transfected mutant proteins was used to determine their subcellular localization. The frequency and type of FP/TMEM127 mutation or deletion was assessed and correlated with clinical variables; the subcellular localization of 5 overexpressed mutants was compared with wild-type FP/TMEM127 protein. We identified 19 potentially pathogenic FP/TMEM127 germline mutations in 20 independent families, but no large deletions were detected. All mutation carriers had adrenal tumors, including 7 bilateral (P = 2.7 × 10(-4)) and/or with familial disease (5 of 20 samples; P = .005). The median age at disease onset in the FP/TMEM127 mutation group was similar to that of patients without a mutation (41.5 vs 45 years, respectively; P = .54). The most common presentation was that of a single benign adrenal tumor in patients older than 40 years. Malignancy was seen in 1 mutation carrier (5%). Expression of 5 novel FP/TMEM127 mutations in cell lines revealed diffuse localization of the mutant proteins in contrast with the discrete multiorganelle distribution of wild-type TMEM127. Germline mutations of FP/TMEM127 were associated with pheochromocytoma but not paraganglioma and occurred in an age group frequently excluded from genetic screening algorithms. Disease-associated mutations disrupt intracellular distribution of the FP/TMEM127 protein.

A pilot study of S-1 plus cisplatin versus 5-fluorouracil plus cisplatin for postoperative chemotherapy in histological stage IIIB-IV (M0) gastric cancer.

PubMed

Lee, Sung Sook; Jeung, Hei-Cheul; Chung, Hyun Cheol; Noh, Sung Hoon; Hyung, Woo Jin; Ahn, Ji Yeong; Rha, Sun Young

2012-02-01

Although its efficacy is unproven, 5-fluorouracil plus cisplatin (FP) is used to prevent postoperative relapse in gastric cancer. We investigated the safety and feasibility of S-1 plus cisplatin (SP) vs. FP for stage IIIB-IV (M0) gastric cancer. Following curative resection, 41 stage IIIB-IV (M0) gastric cancer patients were assigned to SP (eight 14-day cycles of S-1 [40 mg/m(2) twice daily] plus cisplatin [60 mg/m(2) day 1] administered every 3 weeks) or FP (six 3-day cycles of FU [1 g/m(2) per day] plus cisplatin [80 mg/m(2) day 1] every 4 weeks). Doses were reduced based on predefined criteria. Patient characteristics were balanced between the two arms. In total, 124 cycles of SP (N = 20, median = 7, range 1-8) and 113 cycles of FP (N = 21, median 6, range 1-6) were administered. The median relative dose intensity per patient was 75% (49.99-100%) for S-1, 100% (75-100%) for cisplatin in SP, and 100% (64-100%) for 5-FU, 100% (60-100%) for cisplatin in FP. The relative dose intensity of FP was stable, while that of SP decreased during treatment. After median follow-up of 7.9 months (3.8-14.55), the median RFS was not reached. Relapse occurred in two (10%) patients on SP and five (23.8%) in the FP arm (P = 0.24). The incidence of grade 3-4 granulocytopenia was 36.8% with SP and 14.3% with FP. Grade 3-4 non-hematologic toxicities included fatigue (5.2% with SP vs. 4.8% with FP), vomiting (10.5% with SP vs. 0% with FP), and infection (5.2% with SP vs. 0% FP). S-1 plus cisplatin was feasible and tolerable as adjuvant treatment for stage IIIB-IV (M0) gastric cancer. However, because of decreased relative dose intensity during treatment, further study is warranted to determine optimal dosage and combination.

Specification of electron radiation environment at GEO and MEO for surface charging estimates

NASA Astrophysics Data System (ADS)

Ganushkina, N.; Dubyagin, S.; Mateo Velez, J. C.; Liemohn, M. W.

2017-12-01

A series of anomalies at GEO have been attributed to electrons of energy below 100 keV, responsible for surface charging. The process at play is charge deposition on covering insulating surfaces and is directly linked to the space environment at a time scale of a few tens of seconds. Even though modern satellites benefited from the analysis of past flight anomalies and losses, it appears that surface charging remains a source of problems. Accurate specification of the space environment at different orbits is of a key importance. We present the operational model for low energy (< 200 keV) electrons in the inner magnetosphere, Inner Magnetosphere Particle Transport and Acceleration model (IMPTAM). This model has been operating online since March 2013 (http://fp7-spacecast.eu and imptam.fmi.fi) and it is driven by the real time solar wind and IMF parameters and by the real time Dst index. The presented model provides the low energy electron flux at all L-shells and at all satellite orbits, when necessary. IMPTAM is used to simulate the fluxes of low energy electrons inside the Earth's magnetosphere at the time of severe events measured on LANL satellites at GEO. There is no easy way to say what will be the flux of keV electrons at MEO when surface charging events are detected at GEO than to use a model. The maximal electron fluxes obtained at MEO (L = 4.6) within a few tens of minutes hours following the LANL events at GEO have been extracted to feed a database of theoretical/numerical worst-case environments for surface charging at MEO. All IMPTAM results are instantaneous, data have not been average. In order to validate the IMPTAM output at MEO, we conduct the statistical analysis of measured electron fluxes onboard Van Allen Probes (ECT HOPE (20 eV-45 keV) and ECT MagEIS (30 - 300 keV) at distances of 4.6 Re. IMPTAM e- flux at MEO is used as input to SPIS, the Spacecraft Plasma Interaction System Software toolkit for spacecraft-plasma interactions and spacecraft charging modelling (http://dev.spis.org/projects/spine/home/spis). The research leading to these results was funded by the European Union Seventh Framework Programme (FP7/2007-2013) under grant agreement No 606716 SPACESTORM and by the European Union's Horizon 2020 research and innovation programme under grant agreement No 637302 PROGRESS.

Ecotoxicity testing and environmental risk assessment of iron nanomaterials for sub-surface remediation - Recommendations from the FP7 project NanoRem.

PubMed

Hjorth, Rune; Coutris, Claire; Nguyen, Nhung H A; Sevcu, Alena; Gallego-Urrea, Juliàn Alberto; Baun, Anders; Joner, Erik J

2017-09-01

Nanoremediation with iron (Fe) nanomaterials opens new doors for treating contaminated soil and groundwater, but is also accompanied by new potential risks as large quantities of engineered nanomaterials are introduced into the environment. In this study, we have assessed the ecotoxicity of four engineered Fe nanomaterials, specifically, Nano-Goethite, Trap-Ox Fe-zeolites, Carbo-Iron ® and FerMEG12, developed within the European FP7 project NanoRem for sub-surface remediation towards a test battery consisting of eight ecotoxicity tests on bacteria (V. fisheri, E. coli), algae (P. subcapitata, Chlamydomonas sp.), crustaceans (D. magna), worms (E. fetida, L. variegatus) and plants (R. sativus, L. multiflorum). The tested materials are commercially available and include Fe oxide and nanoscale zero valent iron (nZVI), but also hybrid products with Fe loaded into a matrix. All but one material, a ball milled nZVI (FerMEG12), showed no toxicity in the test battery when tested in concentrations up to 100 mg/L, which is the cutoff for hazard labeling in chemicals regulation in Europe. However it should be noted that Fe nanomaterials proved challenging to test adequately due to their turbidity, aggregation and sedimentation behavior in aqueous media. This paper provides a number of recommendations concerning future testing of Fe nanomaterials and discusses environmental risk assessment considerations related to these. Copyright © 2017 Elsevier Ltd. All rights reserved.

Evaluation of representativeness of near-surface winds in station measurements, global and regional reanalysis for Germany

NASA Astrophysics Data System (ADS)

Kaspar, Frank; Kaiser-Weiss, Andrea K.; Heene, Vera; Borsche, Michael; Keller, Jan

2015-04-01

Within the preparation activities for a European COPERNICUS Climate Change Service (C3S) several ongoing research projects analyse the potential of global and regional model-based climate reanalyses for applications. A user survey in the FP7-project CORE-CLIMAX revealed that surface wind (10 m) is among the most frequently used parameters of global reanalysis products. The FP7 project UERRA (Uncertainties in Ensembles of Regional Re-Analysis) has the focus on regional European reanalysis and the associated uncertainties, also from a user perspective. Especially in the field of renewable energy planning and production there is a need for climatological information across all spatial scales, i.e., from climatology at a certain site to the spatial scale of national or continental renewable energy production. Here, we focus on a comparison of wind measurements of the Germany's meteorological service (Deutscher Wetterdienst, DWD) with global reanalyses of ECWMF and a regional reanalysis for Europe based on DWD's NWP-model COSMO (performed by the Hans-Ertel-Center for Weather Research, University of Bonn). Reanalyses can provide valuable additional information on larger scale variability, e.g. multi-annual variation over Germany. However, changes in the observing system, model errors and biases have to be carefully considered. On the other hand, the ground-based observation networks partly suffer from change of the station distribution, changes in instrumentation, measurements procedures and quality control as well as local changes which might modify their spatial representativeness. All these effects might often been unknown or hard to characterize, although plenty of the meta-data information has been recorded for the German stations. One focus of the presentation will be the added-value of the regional reanalysis.

The quest for modernisation of traditional Chinese medicine

PubMed Central

2013-01-01

Traditional Chinese medicine (TCM) is an integral part of mainstream medicine in China. Due to its worldwide use, potential impact on healthcare and opportunities for new drug development, TCM is also of great international interest. Recently, a new era for modernisation of TCM was launched with the successful completion of the Good Practice in Traditional Chinese Medicine Research in the Post-genomic Era (GP-TCM) project, the European Union’s Seventh Framework Programme (FP7) coordination action on TCM research. This 3.5-year project that involved inputs from over 200 scientists resulted in the production of 20 editorials and in-depth reviews on different aspects of TCM that were published in a special issue of Journal of Ethnopharmacology (2012; volume 140, issue 3). In this narrative review, we aim to summarise the findings of the FP7 GP-TCM project and highlight the relevance of TCM to modern medicine within a historical and international context. Advances in TCM research since the 1950s can be characterised into three phases: Phase I (1950s-1970s) was fundamental for developing TCM higher education, research and hospital networks in China; Phase II (1980s-2000s) was critical for developing legal, economic and scientific foundations and international networks for TCM; and Phase III (2011 onwards) is concentrating on consolidating the scientific basis and clinical practice of TCM through interdisciplinary, interregional and intersectoral collaborations. Taking into account the quality and safety requirements newly imposed by a globalised market, we especially highlight the scientific evidence behind TCM, update the most important milestones and pitfalls, and propose integrity, integration and innovation as key principles for further modernisation of TCM. These principles will serve as foundations for further research and development of TCM, and for its future integration into tomorrow’s medicine. PMID:23763836

Enhancing data exploitation through DTN-based data transmission protocols

NASA Astrophysics Data System (ADS)

Daglis, Ioannis A.; Tsaoussidis, Vassilis; Rontogiannis, Athanasios; Balasis, Georgios; Keramitsoglou, Iphigenia; Paronis, Dimitrios; Sykioti, Olga; Tsinganos, Antonios

2014-05-01

Data distribution and data access are major issues in space sciences and geosciences as they strongly influence the degree of data exploitation. Processing and analysis of large volumes of Earth observation and space/planetary data face two major impediments: limited access capabilities due to narrow connectivity windows between spacecraft and ground receiving stations and lack of sufficient communication and dissemination mechanisms between space data receiving centres and the end-user community. Real-time data assimilation that would be critical in a number of forecasting capabilities is particularly affected by such limitations. The FP7-Space project "Space-Data Routers" (SDR) has the aim of allowing space agencies, academic institutes and research centres to disseminate/share space data generated by single or multiple missions, in an efficient, secure and automated manner. The approach of SDR relies on space internetworking - and in particular on Delay-Tolerant Networking (DTN), which marks the new era in space communications, unifies space and earth communication infrastructures and delivers a set of tools and protocols for space-data exploitation. The project includes the definition of limitations imposed by typical space mission scenarios in which the National Observatory of Athens is currently involved, including space and planetary exploration, as well as satellite-supported geoscience applications. In this paper, we present the mission scenarios, the SDR-application and the evaluation of the associated impact from the space-data router enhancements. The work leading to this paper has received funding from the European Union's Seventh Framework Programme (FP7-SPACE-2010-1) under grant agreement no. 263330 for the SDR (Space-Data Routers for Exploiting Space Data) collaborative research project. This paper reflects only the authors' views and the Union is not liable for any use that may be made of the information contained therein.

The enhancement of environmental literacy of High School students within the Sparkling Science project "Traisen w3"

NASA Astrophysics Data System (ADS)

Poppe, Michaela; Zitek, Andreas; Böck, Kerstin; Scheikl, Sigrid; Heidenreich, Andrea; Kurz-Aigner, Roman; Schrittwieser, Martin; Muhar, Susanne

2015-04-01

Environmental literacy is the knowledge necessary to understand the environment as an ecological system. It comprises the insight in the impact of human behaviour on the natural world and the disposition and motivation to apply ones knowledge, skills and insight in order to make environmentally beneficial decisions as rational citizen. The United Nations Environmental Programme states that young people will face major challenges in providing sufficient water and food, generating energy and adapting to climate change in future. Dealing with these challenges will require a major contribution from science and technology. But even more important, it is an issue of education to transfer the required system understanding as a basis to take informed decisions. In this way an education towards environmental literacy contributes significantly to the personal, social, and professional lives of young people, plays therefore a central role in young person`s "preparedness for life", and is a major prerequisite for sustainable development. For the purpose of developing new and engaging forms of learning, "Sparkling Science" projects are funded by the Federal Ministry of Science, Research and Economy in Austria. These projects target at integrating science with school learning by involving young people into scientific research. Within the Sparkling Science Projects "FlussAu:WOW" and" "Traisen.w3" scientists work together with 15-18-year-old students of an Austrian High School over four years. The projects aim to assess and evaluate crucial functions and processes of riverine landscapes particularly considering the floodplain area in near natural and anthropogenically changed landscapes. Within the first project "FlussAu:WOW" (2012-2014), students and scientists elaborated on indicators for assessing and evaluating the ecological functionality of floodplains and rivers. In a case study in the "Traisen.w3" project (2014-2016), scientists and students will focus at the catchment level of the river Traisen in Lower Austria and investigate ecological and cultural ecosystem services in these river landscapes. From the second year on (2014), students are going to develop qualitative causal models on processes in river floodplain systems by means of the learning software "DynaLearn". It is an engaging, interactive, hierarchically structured learning environment that was developed within the EU-FP7 project "DynaLearn" (http://www.dynalearn.eu) to capture and simulate cause-effect relationships across disciplines and scales. Students work in small groups and are forced to think about processes and interactions of hydrological, biological, ecological, spatial and societal elements. Within this setting the collaborative problem solving competency is necessary to develop by sharing knowledge, understanding and different perspectives. The students start with building their own causal models, perform simulations and develop scenarios for the development of the catchment. Thus the students' understanding of environmental processes in river landscapes is advanced. As an important benefit, scientists learn about viewpoints and conceptions young people have on their environment. Formative evaluations of the effectiveness of different methods of collaboration between scientists and students will be conducted during the whole project. The results of the motivation questionnaires and pre- and mid-tests clearly highlighted the potential of the multi-modal collaboration approach to be used to communicate essential knowledge and skills in environmental understanding.

Real-time in vivo diagnosis of laryngeal carcinoma with rapid fiber-optic Raman spectroscopy

PubMed Central

Lin, Kan; Zheng, Wei; Lim, Chwee Ming; Huang, Zhiwei

2016-01-01

We assess the clinical utility of a unique simultaneous fingerprint (FP) (i.e., 800-1800 cm−1) and high-wavenumber (HW) (i.e., 2800-3600 cm−1) fiber-optic Raman spectroscopy for in vivo diagnosis of laryngeal cancer at endoscopy. A total of 2124 high-quality in vivo FP/HW Raman spectra (normal = 1321; cancer = 581) were acquired from 101 tissue sites (normal = 71; cancer = 30) of 60 patients (normal = 44; cancer = 16) undergoing routine endoscopic examination. FP/HW Raman spectra differ significantly between normal and cancerous laryngeal tissue that could be attributed to changes of proteins, lipids, nucleic acids, and the bound water content in the larynx. Partial least squares-discriminant analysis and leave-one tissue site-out, cross-validation were employed on the in vivo FP/HW tissue Raman spectra acquired, yielding a diagnostic accuracy of 91.1% (sensitivity: 93.3% (28/30); specificity: 90.1% (64/71)) for laryngeal cancer identification, which is superior to using either FP (accuracy: 86.1%; sensitivity: 86.7% (26/30); specificity: 85.9% (61/71)) or HW (accuracy: 84.2%; sensitivity: 76.7% (23/30); specificity: 87.3% (62/71)) Raman technique alone. Further receiver operating characteristic analysis reconfirms the best performance of the simultaneous FP/HW Raman technique for laryngeal cancer diagnosis. We demonstrate for the first time that the simultaneous FP/HW Raman spectroscopy technique can be used for improving real-time in vivo diagnosis of laryngeal carcinoma during endoscopic examination. PMID:27699131

Microanalytical investigation of degradation issues in Byzantine wall paintings

NASA Astrophysics Data System (ADS)

Sotiropoulou, S.; Daniilia, Sister; Miliani, C.; Rosi, F.; Cartechini, L.; Papanikola-Bakirtzis, D.

2008-07-01

The St. Euthymius wall paintings, in the Cathedral of Thessaloniki, dated 1303 AD., are stylistically attributed to the School of Panselinos, one of the most important painters of Palaeologean Art. An in situ non-invasive study has been carried out as part of a MOLAB project (a mobile laboratory accessible through the Eu-ARTECH project, funded by the EC 6th FP) combining different analytical techniques such as XRF, mid-FTIR and UV-vis diffuse reflectance spectroscopy. It was during this comprehensive in situ study that certain scientific queries were raised about sensitive areas, where indications of the phenomena of decay requested further attention. A subsequent laboratory study of selected cross-sections using microscopic analysis with μFTIR, SEM-EDS and μRaman, further confirmed the identification of only the atypical in situ observations. The comparative interpretation of all respective results on the specific regions of interest permitted the identification of several degradation phenomena which justify certain aesthetic or stylistic incoherences in the representations. Namely, (i) thermal dehydration of the yellow ochre explaining the reddish appearance of the flesh tones and halos as an accidental effect of the fire; (ii) thermal degradation of azurite converted to tenorite explaining the atypical instance of dark lightings on the purple garments; (iii) degradation of red lead employed in the lightings of the red garments; (iv) widespread presence of oxalates in the paint surface.

Are Hemorrhoids Associated with False-Positive Fecal Immunochemical Test Results?

PubMed

Kim, Nam Hee; Park, Jung Ho; Park, Dong Il; Sohn, Chong Il; Choi, Kyuyong; Jung, Yoon Suk

2017-01-01

False-positive (FP) results of fecal immunochemical tests (FITs) conducted in colorectal cancer (CRC) screening could lead to performing unnecessary colonoscopies. Hemorrhoids are a possible cause of FP FIT results; however, studies on this topic are extremely rare. We investigated whether hemorrhoids are associated with FP FIT results. A retrospective study was conducted at a university hospital in Korea from June 2013 to May 2015. Of the 34547 individuals who underwent FITs, 3946 aged ≥50 years who underwent colonoscopies were analyzed. Logistic regression analysis was performed to determine factors associated with FP FIT results. Among 3946 participants, 704 (17.8%) showed positive FIT results and 1303 (33.0%) had hemorrhoids. Of the 704 participants with positive FIT results, 165 had advanced colorectal neoplasia (ACRN) and 539 had no ACRN (FP results). Of the 1303 participants with hemorrhoids, 291 showed FP results, of whom 81 showed FP results because of hemorrhoids only. Participants with hemorrhoids had a higher rate of FP results than those without hemorrhoids (291/1176, 24.7% vs. 248/2361, 10.5%; p<0.001). Additionally, the participants with hemorrhoids as the only abnormality had a higher rate of FP results than those experiencing no such abnormalities (81/531, 15.3% vs. 38/1173, 3.2%; p<0.001). In multivariate analysis, the presence of hemorrhoids was identified as an independent predictor of FP results (adjusted odds ratio, 2.76; 95% confidence interval, 2.24-3.40; p<0.001). Hemorrhoids are significantly associated with FP FIT results. Their presence seemed to be a non-negligible contributor of FP results in FIT-based CRC screening programs.

Application of data assimilation to solar wind forecasting models

NASA Astrophysics Data System (ADS)

Innocenti, M.; Lapenta, G.; Vrsnak, B.; Temmer, M.; Veronig, A.; Bettarini, L.; Lee, E.; Markidis, S.; Skender, M.; Crespon, F.; Skandrani, C.; Soteria Space-Weather Forecast; Data Assimilation Team

2010-12-01

Data Assimilation through Kalman filtering [1,2] is a powerful statistical tool which allows to combine modeling and observations to increase the degree of knowledge of a given system. We apply this technique to the forecast of solar wind parameters (proton speed, proton temperature, absolute value of the magnetic field and proton density) at 1 AU, using the model described in [3] and ACE data as observations. The model, which relies on GOES 12 observations of the percentage of the meridional slice of the sun covered by coronal holes, grants 1-day and 6-hours in advance forecasts of the aforementioned quantities in quiet times (CMEs are not taken into account) during the declining phase of the solar cycle and is tailored for specific time intervals. We show that the application of data assimilation generally improves the quality of the forecasts during quiet times and, more notably, extends the periods of applicability of the model, which can now provide reliable forecasts also in presence of CMEs and for periods other than the ones it was designed for. Acknowledgement: The research leading to these results has received funding from the European Commission’s Seventh Framework Programme (FP7/2007-2013) under the grant agreement N. 218816 (SOTERIA project: http://www.soteria-space.eu). References: [1] R. Kalman, J. Basic Eng. 82, 35 (1960); [2] G. Welch and G. Bishop, Technical Report TR 95-041, University of North Carolina, Department of Computer Science (2001); [3] B. Vrsnak, M. Temmer, and A. Veronig, Solar Phys. 240, 315 (2007).

Policy recommendations and cost implications for a more sustainable framework for European human biomonitoring surveys.

PubMed

Joas, Anke; Knudsen, Lisbeth E; Kolossa-Gehring, Marike; Sepai, Ovnair; Casteleyn, Ludwine; Schoeters, Greet; Angerer, Jürgen; Castaño, Argelia; Aerts, Dominique; Biot, Pierre; Horvat, Milena; Bloemen, Louis; Reis, M Fátima; Lupsa, Ioana-Rodica; Katsonouri, Andromachi; Cerna, Milena; Berglund, Marika; Crettaz, Pierre; Rudnai, Peter; Halzlova, Katarina; Mulcahy, Maurice; Gutleb, Arno C; Fischer, Marc E; Becher, Georg; Fréry, Nadine; Jensen, Genon; Van Vliet, Lisette; Koch, Holger M; Den Hond, Elly; Fiddicke, Ulrike; Esteban, Marta; Exley, Karen; Schwedler, Gerda; Seiwert, Margarete; Ligocka, Danuta; Hohenblum, Philipp; Kyrtopoulos, Soterios; Botsivali, Maria; DeFelip, Elena; Guillou, Claude; Reniero, Fabiano; Grazuleviciene, Regina; Veidebaum, Toomas; Mørck, Thit A; Nielsen, Jeanette K S; Jensen, Janne F; Rivas, Teresa C; Sanchez, Jinny; Koppen, Gudrun; Smolders, Roel; Kozepesy, Szilvia; Hadjipanayis, Adamos; Krskova, Andrea; Mannion, Rory; Jakubowski, Marek; Fucic, J Aleksandra; Pereira-Miguel, Jose; Gurzau, Anca E; Jajcaj, Michal; Mazej, Darja; Tratnik, Janja Snoj; Lehmann, Andrea; Larsson, Kristin; Dumez, Birgit; Joas, Reinhard

2015-08-01

The potential of Human Biomonitoring (HBM) in exposure characterisation and risk assessment is well established in the scientific HBM community and regulatory arena by many publications. The European Environment and Health Strategy as well as the Environment and Health Action Plan 2004-2010 of the European Commission recognised the value of HBM and the relevance and importance of coordination of HBM programmes in Europe. Based on existing and planned HBM projects and programmes of work and capabilities in Europe the Seventh Framework Programme (FP 7) funded COPHES (COnsortium to Perform Human Biomonitoring on a European Scale) to advance and improve comparability of HBM data across Europe. The pilot study protocol was tested in 17 European countries in the DEMOCOPHES feasibility study (DEMOnstration of a study to COordinate and Perform Human biomonitoring on a European Scale) cofunded (50%) under the LIFE+ programme of the European Commission. The potential of HBM in supporting and evaluating policy making (including e.g. REACH) and in awareness raising on environmental health, should significantly advance the process towards a fully operational, continuous, sustainable and scientifically based EU HBM programme. From a number of stakeholder activities during the past 10 years and the national engagement, a framework for sustainable HBM structure in Europe is recommended involving national institutions within environment, health and food as well as European institutions such as ECHA, EEA, and EFSA. An economic frame with shared cost implications for national and European institutions is suggested benefitting from the capacity building set up by COPHES/DEMOCOPHES. Copyright © 2014 Elsevier Inc. All rights reserved.

Multispectral imaging system based on laser-induced fluorescence for security applications

NASA Astrophysics Data System (ADS)

Caneve, L.; Colao, F.; Del Franco, M.; Palucci, A.; Pistilli, M.; Spizzichino, V.

2016-10-01

The development of portable sensors for fast screening of crime scenes is required to reduce the number of evidences useful to be collected, optimizing time and resources. Laser based spectroscopic techniques are good candidates to this scope due to their capability to operate in field, in remote and rapid way. In this work, the prototype of a multispectral imaging LIF (Laser Induced Fluorescence) system able to detect evidence of different materials on large very crowded and confusing areas at distances up to some tens of meters will be presented. Data collected as both 2D fluorescence images and LIF spectra are suitable to the identification and the localization of the materials of interest. A reduced scan time, preserving at the same time the accuracy of the results, has been taken into account as a main requirement in the system design. An excimer laser with high energy and repetition rate coupled to a gated high sensitivity ICCD assures very good performances for this purpose. Effort has been devoted to speed up the data processing. The system has been tested in outdoor and indoor real scenarios and some results will be reported. Evidence of the plastics polypropylene (PP) and polyethilene (PE) and polyester have been identified and their localization on the examined scenes has been highlighted through the data processing. By suitable emission bands, the instrument can be used for the rapid detection of other material classes (i.e. textiles, woods, varnishes). The activities of this work have been supported by the EU-FP7 FORLAB project (Forensic Laboratory for in-situ evidence analysis in a post blast scenario).

The MARINA Risk Assessment Strategy: A Flexible Strategy for Efficient Information Collection and Risk Assessment of Nanomaterials

PubMed Central

Bos, Peter M. J.; Gottardo, Stefania; Scott-Fordsmand, Janeck J.; van Tongeren, Martie; Semenzin, Elena; Fernandes, Teresa F.; Hristozov, Danail; Hund-Rinke, Kerstin; Hunt, Neil; Irfan, Muhammad-Adeel; Landsiedel, Robert; Peijnenburg, Willie J. G. M.; Sánchez Jiménez, Araceli; van Kesteren, Petra C. E.; Oomen, Agnes G.

2015-01-01

An engineered nanomaterial (ENM) may actually consist of a population of primary particles, aggregates and agglomerates of various sizes. Furthermore, their physico-chemical characteristics may change during the various life-cycle stages. It will probably not be feasible to test all varieties of all ENMs for possible health and environmental risks. There is therefore a need to further develop the approaches for risk assessment of ENMs. Within the EU FP7 project Managing Risks of Nanoparticles (MARINA) a two-phase risk assessment strategy has been developed. In Phase 1 (Problem framing) a base set of information is considered, relevant exposure scenarios (RESs) are identified and the scope for Phase 2 (Risk assessment) is established. The relevance of an RES is indicated by information on exposure, fate/kinetics and/or hazard; these three domains are included as separate pillars that contain specific tools. Phase 2 consists of an iterative process of risk characterization, identification of data needs and integrated collection and evaluation of data on the three domains, until sufficient information is obtained to conclude on possible risks in a RES. Only data are generated that are considered to be needed for the purpose of risk assessment. A fourth pillar, risk characterization, is defined and it contains risk assessment tools. This strategy describes a flexible and efficient approach for data collection and risk assessment which is essential to ensure safety of ENMs. Further developments are needed to provide guidance and make the MARINA Risk Assessment Strategy operational. Case studies will be needed to refine the strategy. PMID:26633430

The MARINA Risk Assessment Strategy: A Flexible Strategy for Efficient Information Collection and Risk Assessment of Nanomaterials.

PubMed

Bos, Peter M J; Gottardo, Stefania; Scott-Fordsmand, Janeck J; van Tongeren, Martie; Semenzin, Elena; Fernandes, Teresa F; Hristozov, Danail; Hund-Rinke, Kerstin; Hunt, Neil; Irfan, Muhammad-Adeel; Landsiedel, Robert; Peijnenburg, Willie J G M; Sánchez Jiménez, Araceli; van Kesteren, Petra C E; Oomen, Agnes G

2015-11-27

An engineered nanomaterial (ENM) may actually consist of a population of primary particles, aggregates and agglomerates of various sizes. Furthermore, their physico-chemical characteristics may change during the various life-cycle stages. It will probably not be feasible to test all varieties of all ENMs for possible health and environmental risks. There is therefore a need to further develop the approaches for risk assessment of ENMs. Within the EU FP7 project Managing Risks of Nanoparticles (MARINA) a two-phase risk assessment strategy has been developed. In Phase 1 (Problem framing) a base set of information is considered, relevant exposure scenarios (RESs) are identified and the scope for Phase 2 (Risk assessment) is established. The relevance of an RES is indicated by information on exposure, fate/kinetics and/or hazard; these three domains are included as separate pillars that contain specific tools. Phase 2 consists of an iterative process of risk characterization, identification of data needs and integrated collection and evaluation of data on the three domains, until sufficient information is obtained to conclude on possible risks in a RES. Only data are generated that are considered to be needed for the purpose of risk assessment. A fourth pillar, risk characterization, is defined and it contains risk assessment tools. This strategy describes a flexible and efficient approach for data collection and risk assessment which is essential to ensure safety of ENMs. Further developments are needed to provide guidance and make the MARINA Risk Assessment Strategy operational. Case studies will be needed to refine the strategy.

Tsunami Loss Assessment For Istanbul

NASA Astrophysics Data System (ADS)

Hancilar, Ufuk; Cakti, Eser; Zulfikar, Can; Demircioglu, Mine; Erdik, Mustafa

2010-05-01

Tsunami risk and loss assessment incorporating with the inundation mapping in Istanbul and the Marmara Sea region are presented in this study. The city of Istanbul is under the threat of earthquakes expected to originate from the Main Marmara branch of North Anatolian Fault System. In the Marmara region the earthquake hazard reached very high levels with 2% annual probability of occurrence of a magnitude 7+ earthquake on the Main Marmara Fault. Istanbul is the biggest city of Marmara region as well as of Turkey with its almost 12 million inhabitants. It is home to 40% of the industrial facilities in Turkey and operates as the financial and trade hub of the country. Past earthquakes have evidenced that the structural reliability of residential and industrial buildings, as well as that of lifelines including port and harbor structures in the country is questionable. These facts make the management of earthquake risks imperative for the reduction of physical and socio-economic losses. The level of expected tsunami hazard in Istanbul is low as compared to earthquake hazard. Yet the assets at risk along the shores of the city make a thorough assessment of tsunami risk imperative. Important residential and industrial centres exist along the shores of the Marmara Sea. Particularly along the northern and eastern shores we see an uninterrupted settlement pattern with industries, businesses, commercial centres and ports and harbours in between. Following the inundation maps resulting from deterministic and probabilistic tsunami hazard analyses, vulnerability and risk analyses are presented and the socio-economic losses are estimated. This study is part of EU-supported FP6 project ‘TRANSFER'.

A protocol for the development of Mediterranean climate services based on the experiences of the CLIM-RUN case studies

NASA Astrophysics Data System (ADS)

Goodess, Clare; Ruti, Paolo; Rousset, Nathalie

2014-05-01

During the closing stages of the CLIM-RUN EU FP7 project on Climate Local Information in the Mediterranean region Responding to User Needs, the real-world experiences encountered by the case-study teams are being assessed and synthesised to identify examples of good practice and, in particular, to produce the CLIM-RUN protocol for the development of Mediterranean climate services. The specific case studies have focused on renewable energy (Morocco, Spain, Croatia, Cyprus), tourism (Savoie, Tunisia, Croatia, Cyprus) and wild fires (Greece) as well as one cross-cutting case study (Veneto region). They have been implemented following a common programme of local workshops, questionnaires and interviews, with Climate Expert Team and Stakeholder Expert Team members collaborating to identify and translate user needs and subsequently develop climate products and information. Feedback from stakeholders has been essential in assessing and refining these products. The protocol covers the following issues: the overall process and methodological key stages; identification and selection of stakeholders; communication with stakeholders; identification of user needs; translation of needs; producing products; assessing and refining products; methodologies for evaluating the economic value of climate services; and beyond CLIM-RUN - the lessons learnt. Particular emphasis is given to stakeholder analysis in the context of the participatory, bottom-up approach promoted by CLIM-RUN and to the iterative approach taken in the development of climate products. Recommendations are also made for an envisioned three-tier business model for the development of climate services involving climate, intermediary and stakeholder tiers.

Social networks and health policy: the case of misoprostol and the WHO model essential medicine list.

PubMed

Millard, Colin; Brhlikova, Petra; Pollock, Allyson

2015-05-01

The WHO Essential Medicines List (EML) was established to help countries prioritise medicines according to their health care needs. Selection for the List is based on rigorous scrutiny of public health relevance, evidence on efficacy and safety, and comparative cost effectiveness. The WHO ideal is that a medicine and its efficacy are based on science, but in reality a medicine has a social life and the acceptance of a pharmaceutical intervention involves the interaction of a wide array of governmental and civil society organisations, and industry. Misoprostol is a medicine widely used for both abortion and prevention of postpartum haemorrhage in low income countries. Although the evidence for the latter is highly contested it was nevertheless added to the WHO EML in 2011. We use social network analysis to examine the social, political and economic field surrounding the WHO EML applications and health policy. We describe a chronology of the drug's use and of the applications to the WHO EML and carry out a social network analysis of the organisations and individuals involved in the applications, research and dissemination. The research identified a network of 238 organisations and individuals involved in the promotion of misoprostol for postpartum haemorrhage and present at the time of the WHO EML applications. There is a strong interdependency between the funding bodies, civil society organisations, researchers and clinician organisations. The research was part of an EU FP7 funded project on Accessing Medicines in Africa and South Asia (2010-2013). Crown Copyright © 2015. Published by Elsevier Ltd. All rights reserved.

Laser-induced breakdown spectroscopy for the remote detection of explosives at level of fingerprints

NASA Astrophysics Data System (ADS)

Almaviva, S.; Palucci, A.; Lazic, V.; Menicucci, I.; Nuvoli, M.; Pistilli, M.; De Dominicis, L.

2016-04-01

We report the results of the application of Laser-Induced Breakdown Spectroscopy (LIBS) for the detection of some common military explosives and theirs precursors deposited on white varnished car's external and black car's internal or external plastic. The residues were deposited by an artificial silicon finger, to simulate material manipulation by terrorists when preparing a car bomb, leaving traces of explosives on the parts of a car. LIBS spectra were acquired by using a first prototype laboratory stand-off device, developed in the framework of the EU FP7 313077 project EDEN (End-user driven DEmo for CBRNe). The system operates at working distances 8-30 m and collects the LIBS in the spectral range 240-840 nm. In this configuration, the target was moved precisely in X-Y direction to simulate the scanning system, to be implemented successively. The system is equipped with two colour cameras, one for wide scene view and another for imaging with a very high magnification, capable to discern fingerprints on a target. The spectral features of each examined substance were identified and compared to those belonging to the substrate and the surrounding air, and those belonging to possible common interferents. These spectral differences are discussed and interpreted. The obtained results show that the detection and discrimination of nitro-based compounds like RDX, PETN, ammonium nitrate (AN), and urea nitrate (UN) from organic interfering substances like diesel, greasy lubricants, greasy adhesives or oils in fingerprint concentration, at stand-off distance of some meters or tenths of meters is feasible.

Priorities and Future Actions for an Effective Use of Phytotherapy in Livestock—Outputs from an Expert Workshop

PubMed Central

Blanco-Penedo, Isabel; Fernández González, César; Tamminen, Lena-Mari; Sundrum, Albert; Emanuelson, Ulf

2018-01-01

This study reflects on the recognised need for more joined-up, high-quality research on phytotherapy that addresses the current societal challenges in finding alternatives to the use of antibiotics. The study applied a multidisciplinary participatory approach in an expert workshop exercise within the FP7 EU IMPRO project. Prior to this study, a literature review was elaborated on research in the field of phytotherapy as applied to farm animals, cooperation between research bodies and initiatives to reduce the use of antibiotics by using phytotherapeutic remedies. The review was delivered to the participants of the workshop so as to receive feedback on it and enrich the discussion. Different expertise, background in research or veterinary practice, and varying positions regarding phytotherapy were the criteria in targeting participants. A structured workshop was subsequently organised, with questions to experts addressing scientific validation of phytotherapy, effective treatment under farm conditions and necessary developments for the future. Challenges identified by the experts were as follows: poor study designs, lack of reproducibility of studies, poor standardisation of products, cost–benefit concerns, lack of veterinarian training and poor data availability. To overcome obstacles, the need for improved study designs for clinical trials was given priority in order to prove the efficacy of remedies and to implement a monitoring system which enables the assessment of the effectiveness of treatments in farm practice. Reflections in this report are intended to be a resource for scientists, policy makers and end users for an effective use of phytotherapy at farm level. PMID:29404346

A virtual reality interface for pre-planning of surgical operations based on a customized model of the patient

NASA Astrophysics Data System (ADS)

Witkowski, Marcin; Lenar, Janusz; Sitnik, Robert; Verdonschot, Nico

2012-03-01

We present a human-computer interface that enables the operator to plan a surgical procedure on the musculoskeletal (MS) model of the patient's lower limbs, send the modified model to the bio-mechanical analysis module, and export the scenario parameters to the surgical navigation system. The interface provides the operator with tools for: importing customized MS model of the patient, cutting bones and manipulating/removal of bony fragments, repositioning muscle insertion points, muscle removal and placing implants. After planning the operator exports the modified MS model for bio-mechanical analysis of the functional outcome. If the simulation result is satisfactory the exported scenario data may be directly used during the actual surgery. The advantages of the developed interface are the possibility of installing it in various hardware configurations and coherent operation regardless of the devices used. The hardware configurations proposed to be used with the interface are: (a) a standard computer keyboard and mouse, and a 2-D display, (b) a touch screen as a single device for both input and output, or (c) a 3-D display and a haptic device for natural manipulation of 3-D objects. The interface may be utilized in two main fields. Experienced surgeons may use it to simulate their intervention plans and prepare input data for a surgical navigation system while student or novice surgeons can use it for simulating results of their hypothetical procedure. The interface has been developed in the TLEMsafe project (www.tlemsafe.eu) funded by the European Commission FP7 program.

Experimental design-based strategy for the simulation of complex gaseous mixture spectra to detect drug precursors

NASA Astrophysics Data System (ADS)

Calderisi, Marco; Ulrici, Alessandro; Pigani, Laura; Secchi, Alberto; Seeber, Renato

2012-09-01

The EU FP7 project CUSTOM (Drugs and Precursor Sensing by Complementing Low Cost Multiple Techniques) aims at developing a new sensing system for the detection of drug precursors in gaseous samples, which includes an External Cavity-Quantum Cascade Laser Photo-Acoustic Sensor (EC-QCLPAS) that is in the final step of realisation. Thus, a simulation based on FT-IR literature spectra has been accomplished, where the development of a proper strategy for the design of the composition of the environment, as much as possible realistic and representative of different scenarios, is of key importance. To this aim, an approach based on the combination of signal processing and experimental design techniques has been developed. The gaseous mixtures were built by adding the considered 4 drug precursor (target) species to the gases typically found in atmosphere, taking also into account possible interfering species. These last chemicals were selected considering custom environments (20 interfering chemical species), whose concentrations have been inferred from literature data. The spectra were first denoised by means of a Fast Wavelet Transform-based algorithm; then, a procedure based on a sigmoidal transfer function was developed to multiply the pure components spectra by the respective concentration values, in a way to correctly preserve background intensity and shape, and to operate only on the absorption bands. The noise structure of the EC-QCLPAS was studied using sample spectra measured with a prototype instrument, and added to the simulated mixtures. Finally a matrix containing 5000 simulated spectra of gaseous mixtures was built up.

Towards drought risk mapping on a pan-European scale

NASA Astrophysics Data System (ADS)

Blauhut, Veit; Gudmundsson, Lukas; Stahl, Kerstin; Seneviratne, Sonia

2014-05-01

Drought is a very complex and multifarious natural hazard, which causes a variety of direct and indirect environmental and socio-economic impacts. For the last 30 years, droughts in Europe caused over 100 billion Euros of losses from impacts in various sectors e.g. agriculture, water quality or energy production. Despite the apparent importance of this hazard observed pan-European drought impacts have not yet been quantitatively related to the most important climatological drivers. Fundamentally, a common approach to describe drought risk on a pan-European scale is still missing. This contribution presents an approach for linking climatological drought indices with observed drought impacts at the European scale. Standardized precipitation index (SPI) and standardized precipitation and evapotranspiration index (SPEI) for different time scales were calculated based on E-OBS data and are used to describe the drought hazard. Data from the European Drought Impact Inventory (EDII) compiled by the EU FP7 Drought R&SPI (Fostering European Drought Research and Science-Policy Interfacing) project are used as a proxy for multi-sectorial (impact categories) vulnerability following the assumption that a reported impact reflects a region's vulnerability to the hazard. Drought risk is then modelled statistically by applying logistic regression to estimate the probability of impact report occurrence as a function of SPI and SPEI. This approach finally allows to map the probability of drought impact occurrence on a year by year basis. The emerging patterns compare well to many known European drought events. Such maps may become an essential component of Drought Risk Management to foster resilience for this hazard at the large scale.

Soil slurry reactors for the assessment of contaminant biodegradation

NASA Astrophysics Data System (ADS)

Toscano, G.; Colarieti, M. L.; Greco, G.

2012-04-01

Slurry reactors are frequently used in the assessment of feasibility of biodegradation in natural soil systems. The rate of contaminant removal is usually quantified by zero- or first-order kinetics decay constants. The significance of such constants for the evaluation of removal rate in the field could be questioned because the slurry reactor is a water-saturated, well-stirred system without resemblance with an unsaturated fixed bed of soil. Nevertheless, a kinetic study with soil slurry reactors can still be useful by means of only slightly more sophisticated kinetic models than zero-/first-order decay. The use of kinetic models taking into account the role of degrading biomass, even in the absence of reliable experimental methods for its quantification, provides further insight into the effect of nutrient additions. A real acceleration of biodegradation processes is obtained only when the degrading biomass is in the growth condition. The apparent change in contaminant removal course can be useful to diagnose biomass growth without direct biomass measurement. Even though molecular biology techniques are effective to assess the presence of potentially degrading microorganism in a "viable-but-nonculturable" state, the attainment of conditions for growth is still important to the development of enhanced remediation techniques. The methodology is illustrated with reference to data gathered for two test sites, Oslo airport Gardermoen in Norway (continuous contamination by aircraft deicing fluids) and the Trecate site in Italy (aged contamination by crude oil spill). This research is part of SoilCAM project (Soil Contamination, Advanced integrated characterisation and time-lapse Monitoring 2008-2012, EU-FP7).

Grouping and Read-Across Approaches for Risk Assessment of Nanomaterials.

PubMed

Oomen, Agnes G; Bleeker, Eric A J; Bos, Peter M J; van Broekhuizen, Fleur; Gottardo, Stefania; Groenewold, Monique; Hristozov, Danail; Hund-Rinke, Kerstin; Irfan, Muhammad-Adeel; Marcomini, Antonio; Peijnenburg, Willie J G M; Rasmussen, Kirsten; Jiménez, Araceli Sánchez; Scott-Fordsmand, Janeck J; van Tongeren, Martie; Wiench, Karin; Wohlleben, Wendel; Landsiedel, Robert

2015-10-26

Physicochemical properties of chemicals affect their exposure, toxicokinetics/fate and hazard, and for nanomaterials, the variation of these properties results in a wide variety of materials with potentially different risks. To limit the amount of testing for risk assessment, the information gathering process for nanomaterials needs to be efficient. At the same time, sufficient information to assess the safety of human health and the environment should be available for each nanomaterial. Grouping and read-across approaches can be utilised to meet these goals. This article presents different possible applications of grouping and read-across for nanomaterials within the broader perspective of the MARINA Risk Assessment Strategy (RAS), as developed in the EU FP7 project MARINA. Firstly, nanomaterials can be grouped based on limited variation in physicochemical properties to subsequently design an efficient testing strategy that covers the entire group. Secondly, knowledge about exposure, toxicokinetics/fate or hazard, for example via properties such as dissolution rate, aspect ratio, chemical (non-)activity, can be used to organise similar materials in generic groups to frame issues that need further attention, or potentially to read-across. Thirdly, when data related to specific endpoints is required, read-across can be considered, using data from a source material for the target nanomaterial. Read-across could be based on a scientifically sound justification that exposure, distribution to the target (fate/toxicokinetics) and hazard of the target material are similar to, or less than, the source material. These grouping and read-across approaches pave the way for better use of available information on nanomaterials and are flexible enough to allow future adaptations related to scientific developments.

Submarine slope earthquake-induced instability and associated tsunami generation potential along the Hyblean-Malta Escarpment (offshore eastern Sicily, Italy)

NASA Astrophysics Data System (ADS)

Ausilia Paparo, Maria; Pagnoni, Gianluca; Zaniboni, Filippo; Tinti, Stefano

2016-04-01

The stability analysis of offshore margins is an important step for the assessment of natural hazard: the main challenge is to evaluate the potential slope failures and the consequent occurrence of submarine tsunamigenic landslides to mitigate the potential coastal damage to inhabitants and infrastructures. But the limited geotechnical knowledge of the underwater soil and the controversial scientific interpretation of the tectonic units make it often difficult to carry out this type of analysis reliably. We select the Hyblean-Malta Escarpment (HME), the main active geological structure offshore eastern Sicily, because the amount of data from historical chronicles, the records about strong earthquakes and tsunami, and the numerous geological offshore surveys carried out in recent years make the region an excellent scenario to evaluate slope failures, mass movements triggered by earthquakes and the consequent tsunamis. We choose several profiles along the HME and analyse their equilibrium conditions using the Minimun Lithostatic Deviation (MLD) method (Tinti and Manucci, 2006, 2008; Paparo et al. 2013), that is based on the limit-equilibrium theory. Considering the morphological and geotechnical features of the offshore slopes, we prove that large-earthquake shaking may lead some zones of the HME to instability, we evaluate the expected volumes involved in sliding and compute the associated landslide-tsunami through numerical tsunami simulations. This work was carried out in the frame of the EU Project called ASTARTE - Assessment, STrategy And Risk Reduction for Tsunamis in Europe (Grant 603839, 7th FP, ENV.2013.6.4-3).

European Network of Bipolar Research Expert Centre (ENBREC): a network to foster research and promote innovative care.

PubMed

Henry, Chantal; Andreassen, Ole A; Barbato, Angelo; Demotes-Mainard, Jacques; Goodwin, Guy; Leboyer, Marion; Vieta, Eduard; Nolen, Willem A; Kessing, Lars Vedel; Scott, Jan; Bauer, Michael

2013-01-01

Bipolar disorders rank as one of the most disabling illnesses in working age adults worldwide. Despite this, the quality of care offered to patients with this disorder is suboptimal, largely due to limitations in our understanding of the pathology. Improving this scenario requires the development of a critical mass of expertise and multicentre collaborative projects. Within the framework of the European FP7 programme, we developed a European Network of Bipolar Research Expert Centres (ENBREC) designed specifically to facilitate EU-wide studies. ENBREC provides an integrated support structure facilitating research on disease mechanisms and clinical outcomes across six European countries (France, Germany, Italy, Norway, Spain and the UK). The centres are adopting a standardised clinical assessment that explores multiple aspects of bipolar disorder through a structured evaluation designed to inform clinical decision-making as well as being applicable to research. Reliable, established measures have been prioritised, and instruments have been translated and validated when necessary. An electronic healthcare record and monitoring system (e-ENBREC©) has been developed to collate the data. Protocols to conduct multicentre clinical observational studies and joint studies on cognitive function, biomarkers, genetics, and neuroimaging are in progress; a pilot study has been completed on strategies for routine implementation of psycho-education. The network demonstrates 'proof of principle' that expert centres across Europe can collaborate on a wide range of basic science and clinical programmes using shared protocols. This paper is to describe the network and how it aims to improve the quality and effectiveness of research in a neglected priority area.

Integrating family planning and HIV services in western Kenya: the impact on HIV-infected patients' knowledge of family planning and male attitudes toward family planning.

PubMed

Onono, Maricianah; Guzé, Mary A; Grossman, Daniel; Steinfeld, Rachel; Bukusi, Elizabeth A; Shade, Starley; Cohen, Craig R; Newmann, Sara J

2015-01-01

Little information exists on the impact of integrating family planning (FP) services into HIV care and treatment on patients' familiarity with and attitudes toward FP. We conducted a cluster-randomized trial in 18 public HIV clinics with 12 randomized to integrated FP and HIV services and 6 to the standard referral-based system where patients are referred to an FP clinic. Serial cross-sectional surveys were done before (n = 488 women, 486 men) and after (n = 479 women, 481 men) the intervention to compare changes in familiarity with FP methods and attitudes toward FP between integrated and nonintegrated (NI) sites. We created an FP familiarity score based on the number of more effective FP methods patients could identify (score range: 0-6). Generalized estimating equations were used to control for clustering within sites. An increase in mean familiarity score between baseline (mean = 5.16) and post-intervention (mean = 5.46) occurred with an overall mean change of 0.26 (95% confidence intervals [CI] = 0.09, 0.45; p = 0.003) across all sites. At end line, there was no difference in increase of mean FP familiarity scores at intervention versus control sites (mean = 5.41 vs. 5.49, p = 0.94). We observed a relative decrease in the proportion of males agreeing that FP was "women's business" at integrated sites (baseline 42% to end line 30%; reduction of 12%) compared to males at NI sites (baseline 35% to end line 42%; increase of 7%; adjusted odds ration [aOR] = 0.43; 95% CI = 0.22, 0.85). Following FP-HIV integration, familiarity with FP methods increased but did not differ by study arm. Integration was associated with a decrease in negative attitudes toward FP among men.

Fertility desires and unmet need for family planning among HIV infected individuals in two HIV clinics with differing models of family planning service delivery.

PubMed

Wanyenze, Rhoda K; Matovu, Joseph K B; Kamya, Moses R; Tumwesigye, Nazarius M; Nannyonga, Maria; Wagner, Glenn J

2015-01-28

Eliminating family planning (FP) unmet need among HIV-infected individuals (PLHIV) is critical to elimination of mother-to-child HIV transmission. We assessed FP unmet need among PLHIV attending two clinics with differing models of FP services. Nsambya Home Care provided only FP information while Mulago HIV clinic provided information and contraceptives onsite. In a cross-sectional study conducted between February-June 2011, we documented pregnancies, fertility desires, and contraceptive use among 797 HIV-infected men and women (408 in Mulago and 389 in Nsambya). FP unmet need was calculated among women who were married, unmarried but had sex within the past month, did not desire the last or future pregnancy at all or wished to postpone for ≥ two years and were not using contraceptives. Multivariable analyses for correlates of FP unmet need were computed for each clinic. Overall, 40% (315) had been pregnant since HIV diagnosis; 58% desired the pregnancies. Of those who were not pregnant, 49% (366) did not desire more children at all; 15.7% wanted children then and 35.3% later. The unmet need for FP in Nsambya (45.1%) was significantly higher than that in Mulago at 30.9% (p = 0.008). Age 40+ compared to 18-29 years (OR = 6.05; 95% CI: 1.69, 21.62 in Mulago and OR = 0.21; 95% CI: 0.05, 0.90 in Nsambya), other Christian denominations (Pentecostal and Seventh Day Adventists) compared to Catholics (OR = 7.18; 95% CI: 2.14, 24.13 in Mulago and OR = 0.23; 95% CI: 0.06, 0.80 in Nsambya), and monthly expenditure > USD 200 compared to < USD40 in Nsambya (OR = 0.17; 95% CI: 0.03, 0.90) were associated with FP unmet need. More than half of the pregnancies in this population were desired. Unmet need for FP was very high at both clinics and especially at the clinic which did not have contraceptives onsite. Lower income and younger women were most affected by the lack of contraceptives onsite. Comprehensive and aggressive FP programs are required for fertility support and elimination of FP unmet need among PLHIV, even with integration of FP information and supplies into HIV clinics.

Ionosphere Waves Service - A demonstration

NASA Astrophysics Data System (ADS)

Crespon, François

2013-04-01

In the frame of the FP7 POPDAT project the Ionosphere Waves Service was developed by ionosphere experts to answer several questions: How make the old ionosphere missions more valuable? How provide scientific community with a new insight on wave processes that take place in the ionosphere? The answer is a unique data mining service accessing a collection of topical catalogues that characterize a huge number of Atmospheric Gravity Waves, Travelling Ionosphere Disturbances and Whistlers events. The Ionosphere Waves Service regroups databases of specific events extracted by experts from a ten of ionosphere missions which end users can access by applying specific searches and by using statistical analysis modules for their domain of interest. The scientific applications covered by the IWS are relative to earthquake precursors, ionosphere climatology, geomagnetic storms, troposphere-ionosphere energy transfer, and trans-ionosphere link perturbations. In this presentation we propose to detail the service design, the hardware and software architecture, and the service functions. The service interface and capabilities will be the focus of a demonstration in order to help potential end-users for their first access to the Ionosphere Waves Service portal. This work is made with the support of FP7 grant # 263240.

VESPA: Developing the Planetary Science Virtual Observatory in H2020

NASA Astrophysics Data System (ADS)

Erard, S.; Cecconi, B.; Le Sidaner, P.; Capria, T.; Rossi, A. P.; Schmitt, B.; André, N.; Vandaele, A.-C.; Scherf, M.; Hueso, R.; Maattanen, A.; Thuillot, W.; Achilleos, N.; Marmo, C.; Santolik, O.; Benson, K.; Bollard, Ph.

2015-10-01

The Europlanet H2020 programme will develop a research infrastructure in Horizon 2020. The programme includes a follow-on to the FP7 activity aimed at developing the Planetary Science Virtual Observatory (VO). This activity is called VESPA, which stands for Virtual European Solar and Planetary Access. Building on the IDIS activity of Europlanet FP7, VESPA will distribute more data, will improve the connected tools and infrastructure, and will help developing a community of both users and data providers. One goal of the Europlanet FP7 programme was to set the basis for a European Virtual Observatory in Planetary Science. A prototype has been set up during FP7, most of the activity being dedicated to the definition of standards to handle data in this field. The aim was to facilitate searches in big archives as well as sparse databases, to make on-line data access and visualization possible, and to allow small data providers to make their data available in an interoperable environment with minimum effort. This system makes intensive use of studies and developments led in Astronomy (IVOA), Solar Science (HELIO), plasma physics (SPASE), and space archive services (IPDA). It remains consistent with extensions of IVOA standards.

VESPA: developing the planetary science Virtual Observatory in H2020

NASA Astrophysics Data System (ADS)

Erard, Stéphane; Cecconi, Baptiste; Le Sidaner, Pierre; Capria, Teresa; Rossi, Angelo Pio

2016-04-01

The Europlanet H2020 programme will develop a research infrastructure in Horizon 2020. The programme includes a follow-on to the FP7 activity aimed at developing the Planetary Science Virtual Observatory (VO). This activity is called VESPA, which stands for Virtual European Solar and Planetary Access. Building on the IDIS activity of Europlanet FP7, VESPA will distribute more data, will improve the connected tools and infrastructure, and will help developing a community of both users and data providers. One goal of the Europlanet FP7 programme was to set the basis for a European Virtual Observatory in Planetary Science. A prototype has been set up during FP7, most of the activity being dedicated to the definition of standards to handle data in this field. The aim was to facilitate searches in big archives as well as sparse databases, to make on-line data access and visualization possible, and to allow small data providers to make their data available in an interoperable environment with minimum effort. This system makes intensive use of studies and developments led in Astronomy (IVOA), Solar Science (HELIO), plasma physics (SPASE), and space archive services (IPDA). It remains consistent with extensions of IVOA standards.

EU-Level Competence Development Projects in Agri-Food-Environment: The Involvement of Sectoral Social Partners

ERIC Educational Resources Information Center

Mulder, Martin

2006-01-01

Purpose: The European Commission and social partner organisations at EU level encourage the lifelong development of qualifications and competence. This is reflected in many policy reports and reviews. This paper seeks to show the involvement of social partner organisations at the level of EU-funded competence development projects.…

System understanding as a basis for sustainable decision-making. A science - school collaboration within the Sparkling Science project "Traisen w3"

NASA Astrophysics Data System (ADS)

Poppe, Michaela; Böck, Kerstin; Loach, Andreas; Scheikl, Sigrid; Zitek, Andreas; Heidenreich, Andrea; Kurz-Aigner, Roman; Schrittwieser, Martin; Muhar, Susanne

2016-04-01

Equipping young people with the skills to participate successfully in increasingly complex environments and societies is a central issue of policy makers around the world. Only the understanding of complex socio-environmental systems establishes a basis for making decisions leading to sustainable development. However, OECD Pisa studies indicated, that only a low percentage of 15-year-old students was able to solve straightforward problems. Additionally, students get less interested in natural science education. In Austria "Sparkling Science" projects funded by the Federal Ministry of Science, Research and Economy in Austria target at integrating science with school learning by involving young people into scientific research for the purpose of developing new and engaging forms of interactive, meaningful learning. Within the Sparkling Science Project "Traisen.w3" scientists work together with 15 to 18-year-old students of an Austrian Secondary School over two years to identify and evaluate ecosystem services within the catchment of the river Traisen. One of the aims of the project is to foster system understanding of the youths by multi-modal school activities. To support the development of causal systems thinking, students developed qualitative causal models on processes in the catchment of the river Traisen with an interactive, hierarchically structured learning environment that was developed within the EU-FP7 project "DynaLearn" (http://www.dynalearn.eu) based on qualitative reasoning. Students worked in small groups and were encouraged to interlink entities, processes and simulate the results of the proposed interactions of hydrological, biological, ecological, spatial and societal elements. Within this setting collaborative problem solving competency through sharing knowledge, understanding and different perspectives was developed. Additionally, in several school workshops the ecosystem services concept was used as communication tool to show the multifunctionality of river catchments and to highlight the necessity of a sustainable use. Furthermore a field mapping of a restored and an anthropogenically altered section of the river Traisen was performed by the students in collaboration with the scientists. It aimed on the surveying of specific parameters relevant for the identification of cultural and ecological ecosystem services. To investigate the effects of the different forms of learning on youths' factual, regional and system knowledge, tests were conducted before and after the school activities. The evaluation results of the pre- and post-tests proved that the multi-modal school activities lead to a significantly higher students' knowledge of environmental processes in river landscapes. The analyses of the students` model scenarios for the river catchment Traisen revealed a clear students` understanding of relationships of anthropogenic impacts, morphological and ecological river states and restoration measures. Students` feedback showed high enthusiasm for field work and the application of theoretical knowledge in their regional context. Summarizing, the involvement of secondary school students in the research project "Traisen.w3" can be seen as a successful example of how students` system thinking and motivation for learning can be increased. Ensuring that young people are proficient in system knowledge and understanding also in relation to their own surrounding environment makes it more likely that sustainable considerations are soundly addressed in the future.

Portable air quality sensor unit for participatory monitoring: an end-to-end VESNA-AQ based prototype

NASA Astrophysics Data System (ADS)

Vucnik, Matevz; Robinson, Johanna; Smolnikar, Miha; Kocman, David; Horvat, Milena; Mohorcic, Mihael

2015-04-01

Key words: portable air quality sensor, CITI-SENSE, participatory monitoring, VESNA-AQ The emergence of low-cost easy to use portable air quality sensors units is opening new possibilities for individuals to assess their exposure to air pollutants at specific place and time, and share this information through the Internet connection. Such portable sensors units are being used in an ongoing citizen science project called CITI-SENSE, which enables citizens to measure and share the data. The project aims through creating citizens observatories' to empower citizens to contribute to and participate in environmental governance, enabling them to support and influence community and societal priorities as well as associated decision making. An air quality measurement system based on VESNA sensor platform was primarily designed within the project for the use as portable sensor unit in selected pilot cities (Belgrade, Ljubljana and Vienna) for monitoring outdoor exposure to pollutants. However, functionally the same unit with different set of sensors could be used for example as an indoor platform. The version designed for the pilot studies was equipped with the following sensors: NO2, O3, CO, temperature, relative humidity, pressure and accelerometer. The personal sensor unit is battery powered and housed in a plastic box. The VESNA-based air quality (AQ) monitoring system comprises the VESNA-AQ portable sensor unit, a smartphone app and the remote server. Personal sensor unit supports wireless connection to an Android smartphone via built-in Wi-Fi. The smartphone in turn serves also as the communication gateway towards the remote server using any of available data connections. Besides the gateway functionality the role of smartphone is to enrich data coming from the personal sensor unit with the GPS location, timestamps and user defined context. This, together with an accelerometer, enables the user to better estimate ones exposure in relation to physical activities, time and location. The end user can monitor the measured parameters through a smartphone application. The smartphone app implements a custom developed LCSP (Lightweight Client Server Protocol) protocol which is used to send requests to the VESNA-AQ unit and to exchange information. When the data is obtained from the VESNA-AQ unit, the mobile application visualizes the data. It also has an option to forward the data to the remote server in a custom JSON structure over a HTTP POST request. The server stores the data in the database and in parallel translates the data to WFS and forwards it to the main CITI-SENSE platform over WFS-T in a common XML format over HTTP POST request. From there data can be accessed through the Internet and visualised in different forms and web applications developed by the CITI-SENSE project. In the course of the project, the collected data will be made publicly available enabling the citizens to participate in environmental governance. Acknowledgements: CITI-SENSE is a Collaborative Project partly funded by the EU FP7-ENV-2012 under grant agreement no 308524 (www.citi-sense.eu).

Annual and solar cycle dependencies of SuperDARN scatter occurrence and ionospheric convection measurements

NASA Astrophysics Data System (ADS)

Lester, M.; Imber, S. M.; Milan, S. E.

2012-12-01

The Super Dual Auroral Radar Network (SuperDARN) provides a long term data series which enables investigations of the coupled magnetosphere-ionosphere system. The network has been in existence essentially since 1995 when 6 radars were operational in the northern hemisphere and 4 in the southern hemisphere. We have been involved in an analysis of the data over the lifetime of the project and present results here from two key studies. In the first study we calculated the amount of ionospheric scatter which is observed by the radars and see clear annual and solar cycle variations in both hemispheres. The recent extended solar minimum also produces a significant effect in the scatter occurrence. In the second study, we have determined the latitude of the Heppner-Maynard Boundary (HMB) using the northern hemisphere SuperDARN radars. The HMB represents the equatorward extent of ionospheric convection for the interval 1996 - 2011. We find that the average latitude of the HMB at midnight is 61° magnetic latitude during solar the maximum of 2003, but it moves significantly poleward during solar minimum, averaging 64° latitude during 1996, and 68° during 2010. This poleward motion is observed despite the increasing number of low latitude radars built in recent years as part of the StormDARN network, and so is not an artefact of data coverage. We believe that the recent extreme solar minimum led to an average HMB location that was further poleward than the previous solar cycle. We have also calculated the Open-Closed field line Boundary (OCB) from auroral images during a subset of the interval (2000 - 2002) and find that on average the HMB is located equatorward of the OCB by ~7o. We suggest that the HMB may be a useful proxy for the OCB when global images are not available. The work presented in this paper has been undertaken as part of the European Cluster Assimilation Technology (ECLAT) project which is funded through the EU FP7 programme and involves groups at Leicester, Helsinki, Uppsala, FMI, Graz and St. Petersburg. The aim of the project is to provide additional data sets, primarily ground based data, to the Cluster Active Archive, and its successor the Cluster Final Archive, in order to enhance the scientific productivity of the archives.

An analysis of pre-service family planning teaching in clinical and nursing education in Tanzania.

PubMed

Muganyizi, Projestine S; Ishengoma, Joyce; Kanama, Joseph; Kikumbih, Nassoro; Mwanga, Feddy; Killian, Richard; McGinn, Erin

2014-07-12

Promoting family planning (FP) is a key strategy for health, economic and population growth. Sub-Saharan Africa, with one of the lowest contraceptive prevalence and highest fertility rates globally, contributes half of the global maternal deaths. Improving the quality of FP services, including enhancing pre-service FP teaching, has the potential to improve contraceptive prevalence. In efforts to improve the quality of FP services in Tanzania, including provider skills, this study sought to identify gaps in pre-service FP teaching and suggest opportunities for strengthening the training. Data were collected from all medical schools and a representative sample of pre-service nursing, Assistant Medical Officer (AMO), Clinical Officer (CO) and assistant CO schools in mainland Tanzania. Teachers responsible for FP teaching at the schools were interviewed using a semi-structured questionnaire. Observations on availability of teaching resources and other evidence of FP teaching and evaluation were documented. Relevant approved teaching documents were assessed for their suitability as competency-based FP teaching tools against predefined criteria. Quantitative data were analyzed using EPI Info 6 and qualitative data were manually analyzed using content analysis. A total of 35 pre-service schools were evaluated for FP teaching including 30 technical education and five degree offering schools. Of the assessed 11 pre-service curricula, only one met the criteria for suitability of FP teaching. FP teaching was typically theoretical with only 22.9% of all the schools having systems in place to produce graduates who could skillfully provide FP methods. Across schools, the target skills were the same level of competence and skewed toward short acting methods of contraception. Only 23.3% (n = 7) of schools had skills laboratories, 76% (n = 22) were either physically connected or linked to FP clinics. None of the degree providing schools practiced FP at its own teaching hospital. Teachers were concerned with poor practical exposure and lack of teaching material. Pre-service FP teaching in Tanzania is theoretical, poorly guided, and skewed toward short acting methods; a majority of the schools are unable to produce competent FP service providers. Pre-service FP training should be strengthened with more focus on practical skills.

Simultaneous fingerprint and high-wavenumber confocal Raman spectroscopy enhances early detection of cervical precancer in vivo.

PubMed

Duraipandian, Shiyamala; Zheng, Wei; Ng, Joseph; Low, Jeffrey J H; Ilancheran, A; Huang, Zhiwei

2012-07-17

Raman spectroscopy is a vibrational spectroscopic technique capable of nondestructively probing endogenous biomolecules and their changes associated with dysplastic transformation in the tissue. The main objectives of this study are (i) to develop a simultaneous fingerprint (FP) and high-wavenumber (HW) confocal Raman spectroscopy and (ii) to investigate its diagnostic utility for improving in vivo diagnosis of cervical precancer (dysplasia). We have successfully developed an integrated FP/HW confocal Raman diagnostic system with a ball-lens Raman probe for simultaneous acquistion of FP/HW Raman signals of the cervix in vivo within 1 s. A total of 476 in vivo FP/HW Raman spectra (356 normal and 120 precancer) are acquired from 44 patients at clinical colposcopy. The distinctive Raman spectral differences between normal and dysplastic cervical tissue are observed at ~854, 937, 1001, 1095, 1253, 1313, 1445, 1654, 2946, and 3400 cm(-1) mainly related to proteins, lipids, glycogen, nucleic acids and water content in tissue. Multivariate diagnostic algorithms developed based on partial least-squares-discriminant analysis (PLS-DA) together with the leave-one-patient-out, cross-validation yield the diagnostic sensitivities of 84.2%, 76.7%, and 85.0%, respectively; specificities of 78.9%, 73.3%, and 81.7%, respectively; and overall diagnostic accuracies of 80.3%, 74.2%, and 82.6%, respectively, using FP, HW, and integrated FP/HW Raman spectroscopic techniques for in vivo diagnosis of cervical precancer. Receiver operating characteristic (ROC) analysis further confirms the best performance of the integrated FP/HW confocal Raman technique, compared to FP or HW Raman spectroscopy alone. This work demonstrates, for the first time, that the simultaneous FP/HW confocal Raman spectroscopy has the potential to be a clinically powerful tool for improving early diagnosis and detection of cervical precancer in vivo during clinical colposcopic examination.

Single-layer MoS2 - electrical transport properties, devices and circuits

NASA Astrophysics Data System (ADS)

Kis, Andras

2013-03-01

After quantum dots, nanotubes and nanowires, two-dimensional materials in the shape of sheets with atomic-scale thickness represent the newest addition to the diverse family of nanoscale materials. Single-layer molybdenum disulphide (MoS2) , a direct-gap semiconductor is a typical example of these new graphene-like materials that can be produced using the adhesive-tape based cleavage technique originally developed for graphene. The presence of a band gap in MoS2 allowed us to fabricate transistors that can be turned off and operate with negligible leakage currents. Furthermore, our transistors can be used to build simple integrated circuits capable of performing logic operations and amplifying small signals. I will report here on our latest 2D MoS2 transistors with improved performance due to enhanced electrostatic control, showing improved currents and transconductance as well as current saturation. We also record electrical breakdown of our devices and find that MoS2 can support very high current densities, exceeding the current carrying capacity of copper by a factor of fifty. Furthermore, I will show optoelectronic devices incorporating MoS2 with sensitivity that surpasses similar graphene devices by several orders of magnitude. Finally, I will present temperature-dependent electrical transport and mobility measurements that show clear mobility enhancement due to the suppression of the influence of charge impurities with the deposition of an HfO2 capping layer. Financially supported by grants from Swiss National Science Foundation, EU-FP7, EU-ERC and Swiss Nanoscience Institute.

Nanostructured lipid carriers-based flurbiprofen gel after topical administration: acute skin irritation, pharmacodynamics, and percutaneous absorption mechanism.

PubMed

Song, Aihua; Su, Zhen; Li, Sanming; Han, Fei

2015-01-01

In order to assess the preliminary safety and effectiveness of nanostructured lipid carriers-based flurbiprofen gel (FP NLC-gel), the acute irritation test, in vivo pharmacodynamics evaluation and pharmacokinetic study were investigated after topical application. No dropsy and erythema were observed after continuous dosing 7 d of FP NLC-gel on the rabbit skin, and the xylene-induced ear drossy could be inhibited by FP NLC-gel at different dosages. The maximum concentration of FP in rats muscle was 2.03 μg/g and 1.55 μg/g after oral and topical administration, respectively. While the peak concentration in untreated muscle after topical administration was only 0.37 μg/mL. And at any time, following topical administration the mean muscle-plasma concentration ratio Cmuscle/CPlasma was obviously higher than that following oral administration. Results indicated that FP could directly penetrate into the subcutaneous muscle tissue from the administration site. Thus, the developed FP NLC-gel could be a safe and effective vehicle for topical delivery of FP.

The SpaceInn SISMA archive

NASA Astrophysics Data System (ADS)

Rainer, Monica; Poretti, Ennio; Mistò, Angelo; Rosa Panzera, Maria

2017-10-01

The Spectroscopic Indicators in a SeisMic Archive (SISMA) has been built in the framework of the FP7 SpaceInn project to contain the 7013 HARPS spectra observed during the CoRoT asteroseismic groundbased program, along with their variability and asteroseismic indicators. The spectra pertain to 261 stars spread around the whole Herztsprung-Russell diagram: 72 of them were CoRoT targets while the others were observed in order to better characterize their variability classes. The Legacy Data lightcurves of the CoRoT targets are also stored in the archive.

Adeno-Associated Virus Transfer of a Gene Encoding SNAP-25 Resistant to Botulinum Toxin A Attenuates Neuromuscular Paralysis Associated with Botulism

DTIC Science & Technology

2008-04-02

Associated with Botulism Arvind Raghunath ,1 Francesc Perez-Branguli,1 Leonard Smith,2 and J. Oliver Dolly1 1International Centre for Neurotherapeutics...NUMBER 6. AUTHOR(S) Raghunath A Branguli FP Smith L Dolly JO 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION...Neurosci., April 2, 2008 • 28(14):3683–3688 Raghunath et al. • Botulism Combated by Gene Transfer of Mutated S25 horns, containing the cell bodies

Universal test system for system embedded optical interconnect

NASA Astrophysics Data System (ADS)

Pitwon, R.; Wang, K.; Immonen, M.; Schröder, H.; Neitz, M.

2018-02-01

We introduce a universal test and measurement system allowing comparative characterisation of optical transceivers, board-to-board optical connectors and both embedded and passive optical circuit boards. The system comprises a test enclosure with interlocking and interchangeable test cards, allowing different technologies spanning different Technology Readiness Levels to be both characterised alone and in combination with other technologies. They form part of the open test design standards portfolio developed on the FP7 PhoxTroT and H2020 COSMICC projects and allow testing on a common test platform.

Highlights of advances in the field of hydrometeorological research brought about by the DRIHM project

NASA Astrophysics Data System (ADS)

Caumont, Olivier; Hally, Alan; Garrote, Luis; Richard, Évelyne; Weerts, Albrecht; Delogu, Fabio; Fiori, Elisabetta; Rebora, Nicola; Parodi, Antonio; Mihalović, Ana; Ivković, Marija; Dekić, Ljiljana; van Verseveld, Willem; Nuissier, Olivier; Ducrocq, Véronique; D'Agostino, Daniele; Galizia, Antonella; Danovaro, Emanuele; Clematis, Andrea

2015-04-01

The FP7 DRIHM (Distributed Research Infrastructure for Hydro-Meteorology, http://www.drihm.eu, 2011-2015) project intends to develop a prototype e-Science environment to facilitate the collaboration between meteorologists, hydrologists, and Earth science experts for accelerated scientific advances in Hydro-Meteorology Research (HMR). As the project comes to its end, this presentation will summarize the HMR results that have been obtained in the framework of DRIHM. The vision shaped and implemented in the framework of the DRIHM project enables the production and interpretation of numerous, complex compositions of hydrometeorological simulations of flood events from rainfall, either simulated or modelled, down to discharge. Each element of a composition is drawn from a set of various state-of-the-art models. Atmospheric simulations providing high-resolution rainfall forecasts involve different global and limited-area convection-resolving models, the former being used as boundary conditions for the latter. Some of these models can be run as ensembles, i.e. with perturbed boundary conditions, initial conditions and/or physics, thus sampling the probability density function of rainfall forecasts. In addition, a stochastic downscaling algorithm can be used to create high-resolution rainfall ensemble forecasts from deterministic lower-resolution forecasts. All these rainfall forecasts may be used as input to various rainfall-discharge hydrological models that compute the resulting stream flows for catchments of interest. In some hydrological simulations, physical parameters are perturbed to take into account model errors. As a result, six different kinds of rainfall data (either deterministic or probabilistic) can currently be compared with each other and combined with three different hydrological model engines running either in deterministic or probabilistic mode. HMR topics which are allowed or facilitated by such unprecedented sets of hydrometerological forecasts include: physical process studies, intercomparison of models and ensembles, sensitivity studies to a particular component of the forecasting chain, and design of flash-flood early-warning systems. These benefits will be illustrated with the different key cases that have been under investigation in the course of the project. These are four catastrophic cases of flooding, namely the case of 4 November 2011 in Genoa, Italy, 6 November 2011 in Catalonia, Spain, 13-16 May 2014 in eastern Europe, and 9 October 2014, again in Genoa, Italy.

Are Hemorrhoids Associated with False-Positive Fecal Immunochemical Test Results?

PubMed Central

Kim, Nam Hee; Park, Jung Ho; Park, Dong Il; Sohn, Chong Il; Choi, Kyuyong

2017-01-01

Purpose False-positive (FP) results of fecal immunochemical tests (FITs) conducted in colorectal cancer (CRC) screening could lead to performing unnecessary colonoscopies. Hemorrhoids are a possible cause of FP FIT results; however, studies on this topic are extremely rare. We investigated whether hemorrhoids are associated with FP FIT results. Materials and Methods A retrospective study was conducted at a university hospital in Korea from June 2013 to May 2015. Of the 34547 individuals who underwent FITs, 3946 aged ≥50 years who underwent colonoscopies were analyzed. Logistic regression analysis was performed to determine factors associated with FP FIT results. Results Among 3946 participants, 704 (17.8%) showed positive FIT results and 1303 (33.0%) had hemorrhoids. Of the 704 participants with positive FIT results, 165 had advanced colorectal neoplasia (ACRN) and 539 had no ACRN (FP results). Of the 1303 participants with hemorrhoids, 291 showed FP results, of whom 81 showed FP results because of hemorrhoids only. Participants with hemorrhoids had a higher rate of FP results than those without hemorrhoids (291/1176, 24.7% vs. 248/2361, 10.5%; p<0.001). Additionally, the participants with hemorrhoids as the only abnormality had a higher rate of FP results than those experiencing no such abnormalities (81/531, 15.3% vs. 38/1173, 3.2%; p<0.001). In multivariate analysis, the presence of hemorrhoids was identified as an independent predictor of FP results (adjusted odds ratio, 2.76; 95% confidence interval, 2.24–3.40; p<0.001). Conclusion Hemorrhoids are significantly associated with FP FIT results. Their presence seemed to be a non-negligible contributor of FP results in FIT-based CRC screening programs. PMID:27873508

Phenylpyrazole insecticide fipronil induces male infertility in the estuarine meiobenthic crustacean Amphiascus tenuiremis.

PubMed

Cary, Tawnya L; Chandler, G Thomas; Volz, David C; Walse, Spencer S; Ferry, John L

2004-01-15

Copepods are the most abundant arthropods on earth and are often the most important secondary producers in estuarine/marine food webs. The new GABA (gamma-aminobutyric acid)-disrupting insecticide fipronil (FP) induces unique sex-specific reproductive dysfunction in male meiobenthic copepods, leading to trans-generational population depression at environmentally realistic concentrations (0.63 microg/L). Using a newly developed 96-well microplate lifecycle bioassay, more than 700 individual Stage-I juveniles were reared to adulthood in as short as 12 days in only 200 microL of control (CTL) or 0.63 microg-FP/L seawater solution. Individual virgin male: female pairs were then cross-mated for all possible combinations within and across rearing treatments and allowed to mate for an additional 12 days in CTL or 0.63 microg-FP/L solution. FP at 0.63 microg/L caused no significant lethality to any mating combinations but evoked 73% or 89% inhibition of reproduction when FP-reared males were mated with either a control- or FP-reared female in FP solution, respectively. In contrast, when CTL-reared males were mated with FP-reared females in FP solution, there was no difference in reproductive success compared to FP-free controls. When FP-reared males were mated with either female group in FP-free solution, these mating pairs displayed a 3-day delay in time to brood sac extrusion but ultimately did reproduce. As fipronil (1) has a high K(ow), (2) is persistent in sediments where meiobenthic copepods live, and (3) has been detected in estuarine waters >0.7 microg/L, it may pose high risk to copepod production in estuarine systems.

Factors influencing survivorship of rehabilitating green sea turtles (Chelonia mydas) with fibropapillomatosis.

PubMed

Page-Karjian, Annie; Norton, Terry M; Krimer, Paula; Groner, Maya; Nelson, Steven E; Gottdenker, Nicole L

2014-09-01

Marine turtle fibropapillomatosis (FP) is a debilitating, infectious neoplastic disease that has reached epizootic proportions in several tropical and subtropical populations of green turtles (Chelonia mydas). FP represents an important health concern in sea turtle rehabilitation facilities. The objectives of this study were to describe the observed epidemiology, biology, and survival rates of turtles affected by FP (FP+ turtles) in a rehabilitation environment; to evaluate clinical parameters as predictors of survival in affected rehabilitating turtles; and to provide information about case progression scenarios and potential outcomes for FP+ sea turtle patients. A retrospective case series analysis was performed using the medical records of the Georgia Sea Turtle Center (GSTC), Jekyll Island, Georgia, USA, during 2009-2013. Information evaluated included signalment, morphometrics, presenting complaint, time to FP onset, tumor score (0-3), co-morbid conditions, diagnostic test results, therapeutic interventions, and case outcomes. Overall, FP was present in 27/362 (7.5%) of all sea turtles admitted to the GSTC for rehabilitation, either upon admittance or during their rehabilitation. Of these, 25 were green and 2 were Kemp's ridley turtles. Of 10 turtles that had only plaque-like FP lesions, 60% had natural tumor regression, all were released, and they were significantly more likely to survive than those with classic FP (P = 0.02 [0.27-0.75, 95% CI]). Turtles without ocular FP were eight times more likely to survive than those with ocular FP (odds ratio = 8.75, P = 0.032 [1.21-63.43, 95% CI]). Laser-mediated tumor removal surgery is the treatment of choice for FP+ patients at the GSTC; number of surgeries was not significantly related to case outcome.

Eye position signals modify vestibulo- and cervico-ocular fast phases during passive yaw rotations in humans.

PubMed

Anastasopoulos, D; Mandellos, D; Kostadima, V; Pettorossi, V E

2002-08-01

We studied the amplitude, latency, and probability of occurrence of fast phases (FP) in darkness to unpredictable vestibular and/or cervical yaw stimulation in normal human subjects. The rotational stimuli were smoothed trapezoidal motion transients of 14 degrees amplitude and 1.25 s duration. Eye position before stimulus application (initial eye position, IEP) was introduced as a variable by asking the subjects to fixate a spot appearing either straight ahead or at 7 degrees eccentric positions. The recordings demonstrated that the generation of FP during vestibular stimulation was facilitated when the whole-body rotation was directed opposite the eccentric IEP. Conversely, FP were attenuated if the whole-body rotation was directed toward the eccentric IEP; i.e., the FP attenuated if they were made to further eccentric positions. Cervical stimulation-induced FP were small and variable in direction when IEP was directed straight ahead before stimulus onset. Eccentric IEPs resulted in large FP, the direction of which was essentially independent of the neck-proprioceptive stimulus. They tended to move the eye toward the primary position, both when the trunk motion under the stationary head was directed toward or away from the IEP. FP dependence on IEP was evident also during head-on-trunk rotations. No consistent interaction between vestibularly and cervically induced FP was found. We conclude that extraretinal eye position signals are able to modify vestibularly evoked reflexive FP in darkness, aiming at minimizing excursions of the eyes away from the primary position. However, neck-induced FP do not relate to specific tasks of stabilization or visual search. By keeping the eyes near the primary position, FP may permit flexibility of orienting responses to incoming stimuli. This recentering bias for both vestibularly and cervically generated FP may represent a visuomotor optimizing strategy.

ROADIDEA- Roadmap for radical innovations in European transport services

NASA Astrophysics Data System (ADS)

Saarikivi, P.

2009-09-01

Weather plays a key role in most traffic accidents, in which over 40.000 European citizens are killed and more than 1,2 million injured every year. It is thus clear that innovations are needed to develop better road weather services to make traffic safer. As transport is responsible of 20% of green house gas emissions in Europe, such services are also needed that make traffic more efficient and reduce congestion. ROADIDEA "Roadmap for radical innovations in European transport services” is a FP7/INFSO Collaboration project that started in 2007 and continues until mid-2010, see www.roadidea.eu. The main objective is to study the potential of the European transport service sector for innovations, analysing available data sources, revealing existing problems and bottlenecks, and developing better methods and models to be utilised in service platforms. These will be capable of providing new, innovative services for various transport user groups. The fourteen partners of ROADIDEA come from Finland, Sweden, the Netherlands, Germany, Italy, Hungary, Croatia and Slovenia. The differences of the existing transport systems and available data sources in these countries are analysed as well as the problems caused by local climate and geography. The innovation process is key activity of the project and will be described in detail in the presentation. It has produced more than 100 ideas during two consecutive brainstorming seminars. Ideas have been analysed and the most potential ones shortlisted for further development. These include e.g. advanced friction models, road condition and fog warning systems, which receive input from hybrid (mobile and fixed combined) observing systems and automated messages from private cars. The Hamburg Port with increasing congestion needs multi-modal traffic model that takes weather into account. New semi-public high-quality ways to travel need to be innovated to reduce the use of private cars in the battle against climate change.

Implications of climate change scenarios for agriculture in alpine regions--a case study in the Swiss Rhone catchment.

PubMed

Fuhrer, J; Smith, P; Gobiet, A

2014-09-15

Coping with climate change in agriculture requires knowledge of trends in agro-climatic conditions with a focus at the smaller scales where decisions are taken. As part of the EU FP7 ACQWA project, the situation was analyzed for agriculture in the case of the Swiss Rhone catchment (Valais) where cultivation of permanent crops (orchards and vineyards) and livestock production are the most important agro-economic activities. The aim of this study was to use daily data from four downscaled and bias corrected transient climate change scenarios to analyze changes in water and temperature related indices over the period 1951-2050 for three locations (Aigle, Sion, Montana) that are representative of different production zones in the catchment. The results indicate that most relevant implications are caused by projected changes in temperature and not in precipitation. They indicate an extension of the thermal growing season with potentially positive effects on pasture and livestock production, most pronounced at the mountain site (Montana), but a trend towards increasing risks of frost in permanent crops and in heat stress for livestock at the valley bottom (Aigle, Sion). The increase in water requirement for irrigation in 2021-2050 relative to 1981-2009 is moderate (4-16%, depending on location). However, in years with low amounts of snow and rain, in small catchments with a nival regime, reduced water supply by rivers could restrict the surface area of grassland that can be irrigated, particularly during springtime. It is concluded that coping with heat-related risks may be most needed at the lower cropland and pasture sites while water-related issues would become more relevant in more elevated locations where pasture-based livestock production is the dominant type of agricultural land use. Copyright © 2013 Elsevier B.V. All rights reserved.

Towards a comparable carbon footprint for local initiatives: The FP7 project TESS

NASA Astrophysics Data System (ADS)

Reusser, Dominik E.; Kropp, Jürgen P.

2014-05-01

TESS (Towards European Societal Sustainability -- www.tess-transition.eu) is a three-year, European-wide research project. It aims to reach an understanding of the potential for community-led initiatives to help deliver a truly sustainable, low-carbon future. Transitions to low-carbon societies take place at multiple and complementary scales. Transition processes are highly dependent on the innovative potential of community-based initiatives and their articulation with appropriate institutional architecture. Community-based initiatives are potentially more adaptable and less constrained by current structural circumstances than top-down policies and can give impetus to large-scale and technology driven changes. TESS will provide an understanding on the upscaling possibilities of such high-potential community-based initiatives by addressing two main questions: What is the impact of community-based initiatives in terms of carbon reduction potential and economic effect? What institutional structures (values, policies and mechanisms) support these initiatives in persisting beyond the initial phase and moving into an acceleration phase, spreading desired impacts? Answers will be provided through (1) a novel measuring, reporting and verification (MRV) framework for benchmarking community-based initiatives. This will enable quantifiable, comparable and standardised evaluation, and (2) the identification of success factors for the emergence, persistence and diffusion of promising initiatives, including online initiatives. We will identify these initiatives through case studies across regions and sectors and produce a systemic understanding of their impact on societal transitions towards sustainability. Our research will be integrated and transdisciplinary, with the unique opportunity to bring together social and natural scientists to foster a transition towards European societal sustainability. Our work will feed into and extend the Climate Adapt database to facilitate reconciliation of mitigation and adaptation and connect to Europe wide evaluation approaches such as the Common Monitoring and Evaluation Framework (CMEF) of the Rural Development Programmes. The poster will show the current state of the initiative selection process and of the method development.

Development of Local Amplification Factors in the NEAM Region for Production of Regional Tsunami Hazard Maps

NASA Astrophysics Data System (ADS)

Harbitz, C. B.; Glimsdal, S.; Løvholt, F.; Orefice, S.; Romano, F.; Brizuela, B.; Lorito, S.; Hoechner, A.; Babeyko, A. Y.

2016-12-01

The standard way of estimating tsunami inundation is by applying numerical depth-averaged shallow-water run-up models. However, for a regional Probabilistic Tsunami Hazard Assessment (PTHA), applying such inundation models may be too time-consuming. A faster, yet less accurate procedure, is to relate the near-shore surface elevations at offshore points to maximum shoreline water levels by using a set of amplification factors based on the characteristics of the incident wave and the bathymetric slope. The surface elevation at the shoreline then acts as a rough approximation for the maximum inundation height or run-up height along the shoreline. An amplification-factor procedure based on a limited set of idealized broken shoreline segments has previously been applied to estimate the maximum inundation heights globally. Here, we present a study where this technique is developed further, by taking into account the local bathymetric profiles. We extract a large number of local bathymetric transects over a significant part of the North East Atlantic, the Mediterranean and connected seas (NEAM) region. For each bathymetric transect, we compute the wave amplification from an offshore control point to points close to the shoreline using a linear shallow-water model for waves of different period and polarity with a sinusoidal pulse wave as input. The amplification factors are then tabulated. We present maximum water levels from the amplification factor method, and compare these with results from conventional inundation models. Finally, we demonstrate how the amplification factor method can be convolved with PTHA results to provide regional tsunami hazard maps. This work has been supported by the European Union's Seventh Framework Programme (FP7/2007-2013) under grant agreement 603839 (Project ASTARTE), and the TSUMAPS-NEAM Project (http://www.tsumapsneam.eu/), co-financed by the European Union Civil Protection Mechanism, Agreement Number: ECHO/SUB/2015/718568/PREV26.

Sensors management in robotic neurosurgery: the ROBOCAST project.

PubMed

Vaccarella, Alberto; Comparetti, Mirko Daniele; Enquobahrie, Andinet; Ferrigno, Giancarlo; De Momi, Elena

2011-01-01

Robot and computer-aided surgery platforms bring a variety of sensors into the operating room. These sensors generate information to be synchronized and merged for improving the accuracy and the safety of the surgical procedure for both patients and operators. In this paper, we present our work on the development of a sensor management architecture that is used is to gather and fuse data from localization systems, such as optical and electromagnetic trackers and ultrasound imaging devices. The architecture follows a modular client-server approach and was implemented within the EU-funded project ROBOCAST (FP7 ICT 215190). Furthermore it is based on very well-maintained open-source libraries such as OpenCV and Image-Guided Surgery Toolkit (IGSTK), which are supported from a worldwide community of developers and allow a significant reduction of software costs. We conducted experiments to evaluate the performance of the sensor manager module. We computed the response time needed for a client to receive tracking data or video images, and the time lag between synchronous acquisition with an optical tracker and ultrasound machine. Results showed a median delay of 1.9 ms for a client request of tracking data and about 40 ms for US images; these values are compatible with the data generation rate (20-30 Hz for tracking system and 25 fps for PAL video). Simultaneous acquisitions have been performed with an optical tracking system and US imaging device: data was aligned according to the timestamp associated with each sample and the delay was estimated with a cross-correlation study. A median value of 230 ms delay was calculated showing that realtime 3D reconstruction is not feasible (an offline temporal calibration is needed), although a slow exploration is possible. In conclusion, as far as asleep patient neurosurgery is concerned, the proposed setup is indeed useful for registration error correction because the brain shift occurs with a time constant of few tens of minutes.

Newly combined 40Ar/39Ar and U-Pb ages of the Upper Cretaceous timescale from Hokkaido, Japan

NASA Astrophysics Data System (ADS)

Gaylor, J. R.; Heredia, B. D.; Quidelleur, X.; Takashima, R.; Nishi, H.; Mezger, K.

2011-12-01

The main targets for GTS next project (www.gtsnext.eu) are to develop highly refined geological time scales, including the Upper Cretaceous. The Cretaceous period is characterised by numerous global anoxic events in the marine realm, rich ammonitic fossil assemblages and specialised foraminifera. However, lack of age diagnostic macro and micro fossils in the North Pacific sections has made it difficult to link these with global sections such as the Western Interior Basin (North America). Using advances with terrestrial C-isotope and planktic foraminifera records within Central Hokkaido we are able to correlate these sections globally. The Cretaceous Yezo group in Central Hokkaido comprises deep marine mudstones and turbidite sandstones interbedded with acidic volcanic tuffs. Using various sections within the Yezo group, we radiometrically dated tuffs at the main stage boundaries in the Upper Cretaceous. The samples derive from the Kotanbetsu, Shumarinai, Tiomiuchi and the Hakkin river sections, spanning the time from the Albian-Cenomanian up until the Campanian-Santonian boundaries, and were dated using 40Ar/39Ar, K/Ar and U-Pb techniques. Recent age constraints in the Hokkaido counterparts (Kotanbetsu sections) show good coherence between radiometric chronometers on the various Upper Cretaceous stage boundaries. These additional ages together with our isotope ages from the different sections around the Hokkaido basin are well linked by the various faunal assemblages and C-isotope curves. The combined radio isotope ages contribute to previous attempts (such as those focused in the Western Interior Basin) supporting the synchronicity of events such as global oceanic anoxic events. Finally, the ages obtained here also compliment the previous C-isotope and planktic foraminifera records allowing for a more precise climatic history of the Northwest Pacific during the Cretaceous. The research within the GTSnext project is funded by the European Community's Seventh Framework Program (FP7/2007-2013) under grant agreement no. 215458.

European Research on life in extreme environments, setting up research priorities and coordinating the community: the CAREX project

NASA Astrophysics Data System (ADS)

Rettberg, P.; Ellis-Evans, C.; Prieur, D.; Loreto, F.; Walter, N.; Le Bris, N.; Elster, J.; Amils, R.; Marteinsson, V.

2008-09-01

Life in Extreme Environments is an emerging area of research in which Europe has considerable expertise but a relatively fragmented research infrastructure. The science of such environments has enormous relevance for our knowledge of the diversity and environmental limits of microbial, plant and animal life and the novel strategies employed for survival and growth. Such studies are essential in understanding how life established on the early Earth and in assessing the possibilities for life on other planetary bodies. These environments are also a rich source of novel exploitable compounds. At the European level, there is a need for better coordination of life in extreme environments research, the FP7-funded CAREX project aims to address this need by developing a clearly identifiable, dynamic and durable community. Establishing this community will encourage greater interdisciplinarity and increasing knowledge of extreme environments. It will provide a target for young career scientists and allow a more focussed dialogue with other science areas, with funding agencies, with industrial groups and with international organisations outside Europe. CAREX will last for three years and with a wide scope covering microbial life, plant adaptation and animal adaptation to various marine, polar, terrestrial extreme environments as well as outer space. CAREX's outputs will include a strategic roadmap for European life in extreme environments research (including enabling technologies), diverse opportunities for knowledge transfer, standardisation of methodologies, encouragement and support for early career scientists and a network of links to relevant organisations. These deliverables together with improved community networking, supported by newsletters, promotional leaflets, a series of science publications and an interactive web portal, will help consolidate the community and its identity. Outcomes will be facilitated through science/technology workshops, diverse forums, field/laboratory protocol intercomparisons, a summer school and individual grants to facilitate knowledge transfer. CAREX has evolved with the key players from the highly successful ESF "Investigating Life in Extreme Environments" initiative. For more information: www.carex-eu.org

Challenges in the participatory assessment of sustainable management practices in dryland ecosystems under regime shifts

NASA Astrophysics Data System (ADS)

Jucker Riva, Matteo; Schwilch, Gudrun; Liniger, Hanspeter

2015-04-01

Regime shifts, defined as a radical and persistent reconfiguration of an ecosystem following a disturbance, have been acknowledged by scientists as a very important aspect of the dynamic of ecosystems. However, their consideration in land management planning remains marginal and limited to specific processes and systems. Current research focuses on mathematical modeling and statistical analysis of spatio-temporal data for specific environmental variables. These methods do not fulfill the needs of land managers, who are confronted with a multitude of processes and pressure types and require clear and simple strategies to prevent regime shift or to increase the resilience of their environment. The EU-FP7 CASCADE project is looking at regime shifts of dryland ecosystems in southern Europe and specifically focuses on rangeland and forest systems which are prone to various land degradation threats. One of the aims of the project is to evaluate the impact of different management practices on the dynamic of the environment in a participatory manner, including a multi-stakeholder evaluation of the state of the environment and of the management potential. To achieve this objective we have organized several stakeholder meetings and we have compiled a review of management practices using the WOCAT methodology, which enables merging scientific and land users knowledge. We highlight here the main challenges we have encountered in applying the notion of regime shift to real world socio-ecological systems and in translating related concepts such as tipping points, stable states, hysteresis and resilience to land managers, using concrete examples from CASCADE study sites. Secondly, we explore the advantages of including land users' knowledge in the scientific understanding of regime shifts. Moreover, we discuss useful alternative concepts and lessons learnt that will allow us to build a participatory method for the assessment of resilient management practices in specific socio-ecological systems and to foster adaptive dryland management.

Development of Local Amplification Factors in the NEAM Region for Production of Regional Tsunami Hazard Maps

NASA Astrophysics Data System (ADS)

Glimsdal, Sylfest; Løvholt, Finn; Bonnevie Harbitz, Carl; Orefice, Simone; Romano, Fabrizio; Brizuela, Beatriz; Lorito, Stefano; Hoechner, Andreas; Babeyko, Andrey

2017-04-01

The standard way of estimating tsunami inundation is by applying numerical depth-averaged shallow-water run-up models. However, for a regional Probabilistic Tsunami Hazard Assessment (PTHA), applying such inundation models may be too time-consuming. A faster, yet less accurate procedure, is to relate the near-shore surface elevations at offshore points to maximum shoreline water levels by using a set of amplification factors based on the characteristics of the incident wave and the bathymetric slope. The surface elevation at the shoreline then acts as a rough approximation for the maximum inundation height or run-up height along the shoreline. An amplification-factor procedure based on a limited set of idealized broken shoreline segments has previously been applied to estimate the maximum inundation heights globally. Here, we present a study where this technique is developed further, by taking into account the local bathymetric profiles. We extract a large number of local bathymetric transects over a significant part of the North East Atlantic, the Mediterranean and connected seas (NEAM region). For each bathymetric transect, we compute the wave amplification from an offshore control point to points close to the shoreline using a linear shallow-water model for waves of different period and polarity with a sinusoidal pulse wave as input. The amplification factors are then tabulated. We present maximum water levels from the amplification factor method, and compare these with results from conventional inundation models. Finally, we demonstrate how the amplification factor method can be convolved with PTHA results to provide regional tsunami hazard maps. This work has been supported by the European Union's Seventh Framework Programme (FP7/2007-2013) under grant agreement 603839 (Project ASTARTE), and the TSUMAPS-NEAM Project (http://www.tsumapsneam.eu/), co-financed by the European Union Civil Protection Mechanism, Agreement Number: ECHO/SUB/2015/718568/PREV26.

A demographic dividend of the FP2020 Initiative and the SDG reproductive health target: Case studies of India and Nigeria.

PubMed

Li, Qingfeng; Rimon, Jose G

2018-02-22

Background: The demographic dividend, defined as the economic growth potential resulting from favorable shifts in population age structure following rapid fertility decline, has been widely employed to advocate improving access to family planning. The current framework focuses on the long-term potential, while the short-term benefits may also help persuade policy makers to invest in family planning. Methods: We estimate the short- and medium-term economic benefits from two major family planning goals: the Family Planning 2020 (FP2020)'s goal of adding 120 million modern contraceptive users by 2020; Sustainable Development Goals (SDG) 3.7 of ensuring universal access to family planning by 2030. We apply the cohort component method to World Population Prospects and National Transfer Accounts data. India and Nigeria, respectively the most populous Asian and African country under the FP2020 initiative, are used as case studies. Results: Meeting the FP2020 target implies that on average, the number of children that need to be supported by every 100 working-age people would decrease by 8 persons in India and 11 persons in Nigeria in 2020; the associated reduction remains at 8 persons in India, but increases to 14 persons in Nigeria by 2030 under the SDG 3.7. In India meeting the FP2020 target would yield a saving of US$18.2 billion (PPP) in consumption expenditures for children and youth in the year 2020 alone, and that increased to US$89.7 billion by 2030. In Nigeria the consumption saved would be US$2.5 billion in 2020 and $12.9 billion by 2030. Conclusions: The tremendous economic benefits from meeting the FP2020 and SDG family planning targets demonstrate the cost-effectiveness of investment in promoting access to contraceptive methods. The gap already apparent between the observed and targeted trajectories indicates tremendous missing opportunities. Accelerated progress is needed to achieve the FP2020 and SDG goals and so reap the demographic dividend.

Standard Specifications for Construction of Roads and Bridges on Federal Highway Projects

DOT National Transportation Integrated Search

1996-01-01

These standard specifications were issued primarily for constructing roads and bridges on Federal Highway projects under the direct administration of the Federal Highway Administration. These specifications are cited as "FP-96" indicating Standard Sp...

[The role of primary care professionals in preventive activitites during epidemics. Focus group assessment of the management of flu pandemic in 2009/2010].

PubMed

Hajnal, Ferenc; Busa, Csilla; Papp, Renáta; Balogh, Sándor

2017-04-01

The experiences gained during the H1N1 flu pandemic in 2009/2010 could serve for a better planning and management of later outbreaks. The EU-sponsored TELL ME project aimed to provide evidence and develop models for improved risk communication during infectious disease crisis. Among its objectives was to develop original communication strategies regarding appropriate messages related to preventative behavior and advice based on uncertainties also addressing vaccine-resistant groups. Focus groups involving family physicians (FPs) were called upon for assessing the main issues during the H1N1 pandemic, the possibilities for improving the preventative process and outcomes. The study demonstrated the key-role of family doctors during outbreaks; patients put their trust in their elected FP, he or she representing a personal example of health behavior. The evidence based information about effectiveness and safety of vaccines are needed in communication towards health professionals. Involvement of health care professionals in the communication provides validity, the communication routine of opinion leaders meant to be used for such purpose. The main media message should be: "For prevention go to see your family doctor". Orv. Hetil., 2017, 158(14), 523-532.

An invisible benefit: integrated project on family planning and parasite control has expanded operations multi-dimensionally.

PubMed

Taniguchi, H

1985-11-01

Resolutions adopted by the 12th Annual Asian Parasite Control/Family Planning (APCO/FP) Conference held in Colombo, Sri Lanka urge the incorporation of quality of life issues of all dimensions in projects of all participating countries. 1 study discussed during the conference concerned health volunteers of the integrated project in Sri Lanka, which analyzes motivating factors which make community young people work on a voluntary basis. Another topic covered was the role of women in the achievement of primary health care. Video reports were presented by Bangladesh on family planning and parasite control activities, Brazil on utilization of existing organizations to improve successful integrated projects, China on making twin concerns of family planning and primary health care, Indonesia on strengthening urban FP/MCH clinics, Korea on health promotion through the integrated project, Malaysia on the NADI program, the Philippines on the Cebu model of integrated health care, and Thailand on fee charging urban programs.

Abbott ARCHITECT iPhenytoin assay versus similar assays for measuring free phenytoin concentrations.

PubMed

Tacker, Danyel Hermes; Robinson, Randy; Perrotta, Peter L

2014-01-01

To measure free phenytoin (FP) concentrations in filtered specimens using the Abbott ARCHITECT iPhenytoin assay and to compare results from this method with results from the Abbott TDx/FLx assays. We verified accuracy, analytic measurement range, and precision for FP measurements. For correlation and therapeutic interval studies, we used filtered calibrators, controls, proficiency-testing materials, and surplus clinical samples. After implementation, we determined proficiency testing results. The analytic measurement range was 2.0 to 25.0 micromol/L. Quality control materials (6.1, 12.6, and 20.1 micromol/L) provided mean (SD) recoveries of 96.1 (5.0%), 99.2 (5.0%), and 99.3 (5.7%), respectively, and coefficients of variation of 5.2%, 5.0%, and 5.8%, respectively. Clinical specimens produced mean (SD) FP recovery levels of 103.7 (10.6%) (bias, 0.1 [0.3] micromol/L). Altering the FP therapeutic range (4.0-8.0 micromol/L) was unnecessary. Proficiency testing yielded consistently acceptable results. Our accuracy, precision, and correlation results were similar for the TDx/FLx and ARCHITECT assays, which demonstrates that the ARCHITECT iPhenytoin assay is acceptable for clinical FP measurements.

Workable solutions to FP in Africa.

PubMed

1991-12-01

The 3rd Pan African Conference on the Integrated Family Planning, Nutrition and Parasite Control Project (PANFRICO III) was held in October 1991 and organized by JOICFP, UNFPA and IPPF. The Ghana IP Steering Committee implemented it. In addition to the 5 IP implementing countries--Ethiopia, the Gambia, Ghana, Tanzania, and Zambia--other countries attending were: Kenya, Lesotho, Madagascar, Mali, Nigeria, Senegal, Sierra Leone, Swaziland, Togo, and Uganda. Governmental and nongovernmental organizations (NGOs) and international groups such as UNFPA, IPPF, FAO, and USAID also attended. The theme was seeking a strategic approach to family planning through primary health care. Participants resolved to increase the support and involvement of African governments in IP implementation. It was recognized that self-reliance, cost effectiveness, and efficient use of resources were important to sustainability. It was also agreed that IP should integrate family planning (FP) with Maternal and Child Health (MCH) and Primary Health Care (PHC) in order to overcome traditional and cultural obstacles to FP and to gain full participation of men in the communities. Horizontal integration was the primary thrust. there was agreement that there should be collaboration between UNFPA, IPPF, and JOICFP, and relevant governments and NGOs. Country-specific attention needs to be paid to expanding IP functions within the 5 IP countries. In Ghana, IP pilot areas have been successful in increasing the FP acceptance rate from 17.4% in 1988 to 51.9% in 1991. IP experiences in Indonesia were presented, including the concept of fee-charged PHC services in order to achieve self-reliance in FP/MCH projects. The response was the request for further technical cooperation between developing countries. The workshop activities were particularly beneficial, and requests were made for discussion of IEC, management, service delivery, nutrition, environmental sanitation, self-reliance, community participation, and evaluation. To further regional IP development within the country, it was suggested that national workshops be held. It was emphasized that FP and population are basic elements of socioeconomic development.

An Approach for harmonizing European Water Portals

NASA Astrophysics Data System (ADS)

Pesquer, Lluís; Stasch, Christoph; Masó, Joan; Jirka, Simon; Domingo, Xavier; Guitart, Francesc; Turner, Thomas; Hinderk Jürrens, Eike

2017-04-01

A number of European funded research projects is developing novel solutions for water monitoring, modeling and management. To generate innovations in the water sector, third parties from industry and the public sector need to take up the solutions and bring them into the market. A variety of portals exists to support this move into the market. Examples on the European level are the EIP Water Online Marketplace(1), the WaterInnEU Marketplace(2), the WISE RTD Water knowledge portal(3), the WIDEST- ICT for Water Observatory(4) or the SWITCH-ON Virtual Product Market and Virtual Water-Science Laboratory(5). Further innovation portals and initiatives exist on the national or regional level, for example, the Denmark knows water platform6 or the Dutch water alliance(7). However, the different portals often cover the same projects, the same products and the same services. Since they are technically separated and have their own data models and databases, people need to duplicate information and maintain it at several endpoints. This requires additional efforts and hinders the interoperable exchange between these portals and tools using the underlying data. In this work, we provide an overview on the existing portals and present an approach for harmonizing and integrating common information that is provided across different portals. The approach aims to integrate the common in formation in a common database utilizing existing vocabularies, where possible. An Application Programming Interface allows access the information in a machine-readable way and utilizing the information in other applications beyond description and discovery purposes. (1) http://www.eip-water.eu/my-market-place (2) https://marketplace.waterinneu.org (3) http://www.wise-rtd.info/ (4) http://iwo.widest.eu (5) http://www.switch-on-vwsl.eu/ (6) http://www.rethinkwater.dk/ (7) http://wateralliance.nl/

A t(1;11) translocation linked to schizophrenia and affective disorders gives rise to aberrant chimeric DISC1 transcripts that encode structurally altered, deleterious mitochondrial proteins

PubMed Central

Eykelenboom, Jennifer E.; Briggs, Gareth J.; Bradshaw, Nicholas J.; Soares, Dinesh C.; Ogawa, Fumiaki; Christie, Sheila; Malavasi, Elise L.V.; Makedonopoulou, Paraskevi; Mackie, Shaun; Malloy, Mary P.; Wear, Martin A.; Blackburn, Elizabeth A.; Bramham, Janice; McIntosh, Andrew M.; Blackwood, Douglas H.; Muir, Walter J.; Porteous, David J.; Millar, J. Kirsty

2012-01-01

Disrupted-In-Schizophrenia 1 (DISC1) was identified as a risk factor for psychiatric illness through its disruption by a balanced chromosomal translocation, t(1;11)(q42.1;q14.3), that co-segregates with schizophrenia, bipolar disorder and depression. We previously reported that the translocation reduces DISC1 expression, consistent with a haploinsufficiency disease model. Here we report that, in lymphoblastoid cell lines, the translocation additionally results in the production of abnormal transcripts due to the fusion of DISC1 with a disrupted gene on chromosome 11 (DISC1FP1/Boymaw). These chimeric transcripts encode abnormal proteins, designated CP1, CP60 and CP69, consisting of DISC1 amino acids 1–597 plus 1, 60 or 69 amino acids, respectively. The novel 69 amino acids in CP69 induce increased α-helical content and formation of large stable protein assemblies. The same is predicted for CP60. Both CP60 and CP69 exhibit profoundly altered functional properties within cell lines and neurons. Both are predominantly targeted to mitochondria, where they induce clustering and loss of membrane potential, indicative of severe mitochondrial dysfunction. There is currently no access to neural material from translocation carriers to confirm these findings, but there is no reason to suppose that these chimeric transcripts will not also be expressed in the brain. There is thus potential for the production of abnormal chimeric proteins in the brains of translocation carriers, although at substantially lower levels than for native DISC1. The mechanism by which inheritance of the translocation increases risk of psychiatric illness may therefore involve both DISC1 haploinsufficiency and mitochondrial deficiency due to the effects of abnormal chimeric protein expression. GenBank accession numbers: DISC1FP1 (EU302123), Boymaw (GU134617), der 11 chimeric transcript DISC1FP1 exon 2 to DISC1 exon 9 (JQ650115), der 1 chimeric transcript DISC1 exon 4 to DISC1FP1 exon 4 (JQ650116), der 1 chimeric transcript DISC1 exon 6 to DISC1FP1 exon 3a (JQ650117). PMID:22547224

Fluticasone Propionate Pharmacogenetics: CYP3A4*22 Polymorphism and Pediatric Asthma Control

PubMed Central

Stockmann, Chris; Fassl, Bernhard; Gaedigk, Roger; Nkoy, Flory; Uchida, Derek A.; Monson, Steven; Reilly, Christopher A.; Leeder, J. Steven; Yost, Garold S.; Ward, Robert M.

2012-01-01

Objective To determine the relationship between allelic variations in genes involved in fluticasone propionate (FP) metabolism and asthma control among children with asthma managed with inhaled FP. Study design The relationship between variability in asthma control scores and genetic variation in drug metabolism was assessed by genotyping nine single nucleotide polymorphisms (SNPs) in CYP3A4, CYP3A5, and CYP3A7. Genotype information was compared with asthma control scores (0 = well-controlled to 15 = poorly-controlled), determined by using a questionnaire modified from the National Heart Lung and Blood Institute Expert Panel 3 guidelines. Results Our study cohort was comprised of 734 children with asthma (mean age 8.8 ± 4.3 years), who were predominantly male (61%) and non-Hispanic Whites (53%); 413 children (56%) were receiving inhaled glucocorticoids daily, of which FP was prescribed most frequently (65%). Among the children receiving daily FP, SNPs in the genes CYP3A5 and CYP3A7 were not associated with asthma control scores. In contrast, asthma control scores were significantly improved among 20 (7%) children with the CYP3A4*22 allele (median 3, range 0-6), as compared with the 201 patients without the CYP3A4*22 allele (median 4, range 0-15) (P=0.02). The presence of CYP3A4*22 was associated with improved asthma control scores by 2.1 points (95% CI: 0.5-3.8). Conclusions The presence of CYP3A4*22, which is associated with decreased hepatic CYP3A4 expression and activity, was accompanied by improved asthma control among FP treated children. Decreased CYP3A4 activity may improve asthma control with inhaled FP. PMID:23290512

Neutron Capture Experiments on Unstable Nuclei

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schwantes, Jon M.; Sudowe, Ralf; Folden, Charles M., III

2005-01-15

The overall objective of this project is the measurement of neutron capture cross sections of importance to stewardship science and astrophysical modeling of nucleosynthesis, while at the same time helping to train the next generation of scientists with expertise relevant to U.S. national nuclear security missions and to stewardship science. A primary objective of this project is to study neutron capture cross sections for various stable and unstable isotopes that will contribute to the Science Based Stockpile Stewardship (SBSS) program by providing improved data for modeling and interpretation of nuclear device performance. Much of the information obtained will also bemore » important in astrophysical modeling of nucleosynthesis. Measurements of these neutron capture cross sections are being conducted in collaboration with researchers at the Los Alamos Neutron Science Center (LANSCE) facility using the unique Detector for Advanced Neutron Capture Experiments (DANCE). In our early discussions with the DANCE group, decisions were made on the first cross sections to be measured and how our expertise in target preparation, radiochemical separations chemistry, and data analysis could best be applied. The initial emphasis of the project was on preparing suitable targets of both natural and separated stable europium isotopes in preparation for the ultimate goal of preparing a sufficiently large target of radioactive 155Eu (t1/2 = 4.7 years) and other radioactive and stable species for neutron cross-section measurements at DANCE. Our Annual Report, ''Neutron Capture Experiments on Unstable Nuclei'' by J. M. Schwantes, R. Sudowe, C. M. Folden III, H. Nitsche, and D. C. Hoffman, submitted to NNSA in December 2003, gives details about the initial considerations and scope of the project. During the current reporting period, electroplated targets of natural Eu together with valuable, stable, and isotopically pure 151Eu and 153Eu, and isotopically separated 154Sm were measured for the first time at the DANCE facility in early 2004. The Eu targets, suitable blanks, Be backing foils, and standards had been sent to the DANCE group in early fall 2003. Some preliminary data analysis was performed and more sophisticated analysis has begun. We developed plans for a suitable computer system for data analysis within our group at Berkeley and had meetings with counterparts at Lawrence Livermore National Laboratory (LLNL) and LANL concerning analysis of these data. Our major emphasis in 2004 has been to develop the separations and processes ultimately required to prepare radioactive targets of 4.7-year 155Eu. Efforts continued to devise an optimum multiprocess procedure suitable for use in separating radioactive 155Eu already produced by irradiation of stable 154Sm in a high neutron flux reactor at the Institut Laue-Langevin in France and shipped to LANL (the 22-min 155Sm neutron-capture product decays to 155Eu). This separation is extremely demanding because the highly radioactive 155Eu must be isolated from about 20 times as much mass of samarium before a target can be prepared for DANCE measurements. After all the procedures have been fully tested the radioactive 155Eu will be separated. The same electroplating methods already used successfully to prepare stable Eu isotope targets will be used to prepare the 155Eu target for DANCE. Discussions were held with LANL radiochemists in the Chemistry (C) Division about appropriate facilities at LANL for conducting the full-scale separation and purification of the radioactive targets. Three more multiprocess separations were developed that generated less chemical and radioactive waste, but they must still be adapted for processing hundred-milligram quantities. Until these separations can be successfully implemented at this scale, standard HPLC procedures will be used for separating and preparing radioactive 155Eu, 2.6-year 147Pm, and 1.9-year 171Tm target materials. Future directions beyond the preparation of radioactive lanthanide targets include closer collaboration with both LLNL and LANL to prepare actinide targets such as plutonium, americium, and curium. Also, the applicability of established and novel techniques will be evaluated for rapid separations of Am and Cm required in the irradiation of 241Am. Lastly, we will conduct a series of experiments aimed at enhancing current methods used to electrodeposit lanthanide and actinide targets on thin Ti and Be backings.« less

Synthesis, characterization, and luminescent properties of Eu3+ dipyridophenazine functionalized complexes for potential bioimaging applications

NASA Astrophysics Data System (ADS)

Beasley, Jeremy

Luminescent properties of lanthanide complexes possess unique characteristics that make them good candidates for possible bioimaging agents and have inspired research initiatives to further explore these materials. However, the toxicity of these metals limits their applications as in-vivo bioimaging agents. One solution that eliminates the toxic effects is to encase these lanthanide complexes in silica. This project was designed to probe the variation in the fluorescence properties of a highly luminescent europium (III) complex, utilizing a fluorinated â-diketonate ligand (thenoyltrifluoroacetone (tta)), upon the substitution of the solvent molecules by various functionalized dipyrido[3,2-a:2',3'-c]phenazine (DPPZ) ligands. A method for covalently attaching, or occluding complexes in silica nanoparticles were also included in the project design. The structure and properties of the functionalized DPPZ ligands and their respective complexes were determined by FT-IR, 1H-NMR, UV-Vis, and fluorescence spectroscopy techniques. UV excitation of the complexes resulted in red luminescence (~ 614 nm) characteristic of trivalent europium ions. The differences in luminescence properties of the complexes are rationalized in terms of the electronic features of the different functionalized DPPZ ligands. The higher overall quantum yield of the un-functionalized DPPZ complex, Eu(tta)3DPPZ (Q.Y.= 7.68 +/- 0.06 %), and the low overall quantum yield observed for Eu(tta)3DPPZ-COOEt (Q.Y.= 1.08 +/- 0.05%), Eu(tta) 3DPPZ-Si (Q.Y.= 0.65+/- 0.04%), Eu(tta)3DPPZ-COOH (Q.Y.= 0.61+/- 0.07 %), Eu(tta)3DPPZ-CH3 (Q.Y.= 0.59+/-0.02 %) are rationalized in terms of how electron donating or withdrawing groups affect their respective ligand-to-metal energy transfer efficiencies. Eu(tta) 3DPPZ was the only complex to show enhanced luminescent properties capable of potential applications in biomedical imaging.

Directions for new developments on statistical design and analysis of small population group trials.

PubMed

Hilgers, Ralf-Dieter; Roes, Kit; Stallard, Nigel

2016-06-14

Most statistical design and analysis methods for clinical trials have been developed and evaluated where at least several hundreds of patients could be recruited. These methods may not be suitable to evaluate therapies if the sample size is unavoidably small, which is usually termed by small populations. The specific sample size cut off, where the standard methods fail, needs to be investigated. In this paper, the authors present their view on new developments for design and analysis of clinical trials in small population groups, where conventional statistical methods may be inappropriate, e.g., because of lack of power or poor adherence to asymptotic approximations due to sample size restrictions. Following the EMA/CHMP guideline on clinical trials in small populations, we consider directions for new developments in the area of statistical methodology for design and analysis of small population clinical trials. We relate the findings to the research activities of three projects, Asterix, IDeAl, and InSPiRe, which have received funding since 2013 within the FP7-HEALTH-2013-INNOVATION-1 framework of the EU. As not all aspects of the wide research area of small population clinical trials can be addressed, we focus on areas where we feel advances are needed and feasible. The general framework of the EMA/CHMP guideline on small population clinical trials stimulates a number of research areas. These serve as the basis for the three projects, Asterix, IDeAl, and InSPiRe, which use various approaches to develop new statistical methodology for design and analysis of small population clinical trials. Small population clinical trials refer to trials with a limited number of patients. Small populations may result form rare diseases or specific subtypes of more common diseases. New statistical methodology needs to be tailored to these specific situations. The main results from the three projects will constitute a useful toolbox for improved design and analysis of small population clinical trials. They address various challenges presented by the EMA/CHMP guideline as well as recent discussions about extrapolation. There is a need for involvement of the patients' perspective in the planning and conduct of small population clinical trials for a successful therapy evaluation.

Brokerage services for Earth Science data: the EuroGEOSS legacy (Invited)

NASA Astrophysics Data System (ADS)

Nativi, S.; Craglia, M.; Pearlman, J.

2013-12-01

Global sustainability research requires an integrated multidisciplinary effort underpinned by a collaborative environment discovering and accessing heterogeneous data across disciplines. Traditionally, interoperability has been achieved by implementing federation of systems. The federating approach entails the adoption of a set of common technologies and standards. This presentation argues that for complex (and uncontrolled) environments (such as global, multidisciplinary, and voluntary-based infrastructures) federated solutions must be completed and enhanced by a brokering approach -making available a set of brokerage services. In fact, brokerage services allows a cyber-infrastructure to lower entry barriers (for both data producers and users) and to better address the different domain specificities. The brokering interoperability approach was successfully experimented by the EuroGEOSS project, funded by the European Commission in the FP7 framework (see http://www.eurogeoss.eu). The EuroGEOSS Brokering framework provided the EuroGEOSS Capacity with multidisciplinary interoperability functionalities. This platform was developed applying several of the principles/requirements that characterize the System of Systems (SoS) approach and the Internet of Services (IoS) philosophy. The framework consists of three main brokers (middleware components implementing intermediation and harmonization services): a basic Discovery Broker, an advanced Semantic Discovery Broker, and an Access Broker. They are empowered by a suite of tools developed by the ESSI-lab of the CNR-IIA, called: GI-cat, GI-sem, and GI-axe. The EuroGEOSS brokering framework was considered and successfully adopted by cross-disciplinary initiatives (notably GEOSS: Global Earth Observation System of Systems). The brokerage services have been advanced and extended; the new brokering framework is called GEO DAB (Discovery and Access Broker). New brokerage services have been developed in the framework of other European Commission funded projects (e.g. GeoViQua). More recently, the NSF EarthCube initiative decided to fund a project dealing with brokerage services. In the framework of the GEO AIP-6 (Architecture Implementation Pilot -phase 6), the presented brokerage platform has been used by the Water Working Group to carry out improved data access for parameterization and model development.

Coronal Dynamics at Recent Total Solar Eclipses

NASA Astrophysics Data System (ADS)

Pasachoff, J. M.; Lu, M.; Davis, A. B.; Demianski, M.; Rusin, V.; Saniga, M.; Seaton, D. B.; Lucas, R.; Babcock, B. A.; Dantowitz, R.; Gaintatzis, P.; Seeger, C. H.; Malamut, C.; Steele, A.

2014-12-01

Our composite images of the solar corona based on extensive imaging at the total solar eclipses of 2010 (Easter Island), 2012 (Australia), and 2013 (Gabon) reveal several coronal mass ejections and other changes in coronal streamers and in polar plumes. Our resultant spatial resolution is finer than that available in imaging from spacecraft, including that from SOHO/LASCO or STEREO. We trace the eruptions back to their footpoints on the sun using imaging from SDO and SWAP, and follow them upwards through the corona, measuring velocities. The high-resolution computer compositing by Miloslav Druckmüller and Hana Druckmüllerová (2010 and 2013) and Pavlos Gaintatzis (2012) allows comparison of our images with those taken at intervals of minutes or hours along the totality path. Williams College's 2013 eclipse expedition was supported in part by grant 9327-13 from National Geographic Society/Committee for Research and Exploration. Our work on the 2012 eclipse is supported in part by grant AGS-1047726 from Solar Terrestrial Research/NSF AGS. V.R. and M.S. were partially supported by the VEGA grant agency project 2/0098/10 and 2/0003/13 (Slovak Academy of Sciences) and Grant 0139-12 from NG/CRE, and Hana Druckmüllerová by grant 205/09/1469 of the Czech Science Foundation. M.L. was supported by Sigma Xi. C.M. was a Keck Northeast Astronomy Consortium Summer Fellow, supported at Williams College by REU/NSF grant AST-1005024. Partial support was provided by U.S. Department of Defense's ASSURE program. J.M.P. thanks Caltech's Planetary Sciences Department for hospitality. Support for D.B.S. and SWAP came from PRODEX grant C90345 managed by ESA in collaboration with the Belgian Federal Science Policy Office (BELSPO) in support of the PROBA2/SWAP mission, and from the EC's Seventh Framework Programme (FP7/2007-2013) under grant 218816 (SOTERIA project, www.soteria-space.eu). SWAP is a project of the Centre Spatial de Liège and the Royal Observatory of Belgium funded by BELSPO.

The CMIP5 archive architecture: A system for petabyte-scale distributed archival of climate model data

NASA Astrophysics Data System (ADS)

Pascoe, Stephen; Cinquini, Luca; Lawrence, Bryan

2010-05-01

The Phase 5 Coupled Model Intercomparison Project (CMIP5) will produce a petabyte scale archive of climate data relevant to future international assessments of climate science (e.g., the IPCC's 5th Assessment Report scheduled for publication in 2013). The infrastructure for the CMIP5 archive must meet many challenges to support this ambitious international project. We describe here the distributed software architecture being deployed worldwide to meet these challenges. The CMIP5 architecture extends the Earth System Grid (ESG) distributed architecture of Datanodes, providing data access and visualisation services, and Gateways providing the user interface including registration, search and browse services. Additional features developed for CMIP5 include a publication workflow incorporating quality control and metadata submission, data replication, version control, update notification and production of citable metadata records. Implementation of these features have been driven by the requirements of reliable global access to over 1Pb of data and consistent citability of data and metadata. Central to the implementation is the concept of Atomic Datasets that are identifiable through a Data Reference Syntax (DRS). Atomic Datasets are immutable to allow them to be replicated and tracked whilst maintaining data consistency. However, since occasional errors in data production and processing is inevitable, new versions can be published and users notified of these updates. As deprecated datasets may be the target of existing citations they can remain visible in the system. Replication of Atomic Datasets is designed to improve regional access and provide fault tolerance. Several datanodes in the system are designated replicating nodes and hold replicas of a portion of the archive expected to be of broad interest to the community. Gateways provide a system-wide interface to users where they can track the version history and location of replicas to select the most appropriate location for download. In addition to meeting the immediate needs of CMIP5 this architecture provides a basis for the Earth System Modeling e-infrastructure being further developed within the EU FP7 IS-ENES project.