Science.gov

Sample records for fr13my10n additional designations

  1. 77 FR 14592 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-12

    ... Office of Foreign Assets Control Additional Designations, Foreign Narcotics Kingpin Designation Act... whose property and interests in property have ] been blocked pursuant to the Foreign Narcotics Kingpin... the activities of significant foreign narcotics traffickers and their organizations on a...

  2. 77 FR 69707 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-20

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF THE TREASURY Office of Foreign Assets Control Additional Designations, Foreign Narcotics Kingpin Designation Act... property and interests in property has been blocked pursuant to the Foreign Narcotics Kingpin...

  3. 76 FR 25405 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-04

    ... Office of Foreign Assets Control Additional Designations, Foreign Narcotics Kingpin Designation Act... whose property and interests in property have been blocked pursuant to the Foreign Narcotics Kingpin... the activities of significant foreign narcotics traffickers and their organizations on a...

  4. 78 FR 53007 - Additional Designation, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-27

    ... of the Central Intelligence Agency, the Director of the Federal Bureau of Investigation, the... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF THE TREASURY Office of Foreign Assets Control Additional Designation, Foreign Narcotics Kingpin Designation Act...

  5. Design and additive manufacture for flow chemistry.

    PubMed

    Capel, Andrew J; Edmondson, Steve; Christie, Steven D R; Goodridge, Ruth D; Bibb, Richard J; Thurstans, Matthew

    2013-12-01

    We review the use of additive manufacturing (AM) as a novel manufacturing technique for the production of milli-scale reactor systems. Five well-developed additive manufacturing techniques: stereolithography (SL), multi-jet modelling (MJM), selective laser melting (SLM), laser sintering (LS) and fused deposition modelling (FDM) were used to manufacture a number of miniaturised reactors which were tested using a range of organic and inorganic reactions. PMID:24100659

  6. 14 CFR 13.107 - Designation of additional parties.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Designation of additional parties. 13.107... Investigation § 13.107 Designation of additional parties. (a) The Presiding Officer may designate additional persons as parties to the investigation, if in the discretion of the Presiding Officer, it will aid in...

  7. 76 FR 58562 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-21

    ... the Attorney General, the Director of the Central Intelligence Agency, the Director of the Federal... Designation Act AGENCY: Office of Foreign Assets Control, Treasury. ACTION: Notice. SUMMARY: The...

  8. DETAIL OF PLAQUE WITH ADDITIONAL DESIGN AND CONSTRUCTION INFORMATION, SOUTHEAST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    DETAIL OF PLAQUE WITH ADDITIONAL DESIGN AND CONSTRUCTION INFORMATION, SOUTHEAST ABUTMENT - Connecticut Avenue Bridge, Spans Rock Creek & Potomac Parkway at Connecticut Avenue, Washington, District of Columbia, DC

  9. Laser Additive Manufacturing and Bionics: Redefining Lightweight Design

    NASA Astrophysics Data System (ADS)

    Emmelmann, C.; Sander, P.; Kranz, J.; Wycisk, E.

    New layer wise manufacturing technologies such as Laser Additive Manufacturing (LAM) allow innovative approaches to product design. Especially for lightweight design in aircraft applications LAM offers new possibilities for load-adapted structures. However, to fully capture lightweight potential of LAM technologies new design guidelines and processes have to be developed. A novel approach to extreme lightweight design is realized by incorporating structural optimization tools, bionic structures and LAM guidelines into one design process. By consequently following this design process designers can achieve lightweight savings in designing new aircraft structures.

  10. The design of impact absorbing structures for additive manufacture

    NASA Astrophysics Data System (ADS)

    Brennan-Craddock, J.; Brackett, D.; Wildman, R.; Hague, R.

    2012-08-01

    Additive manufacturing (AM) is increasingly becoming a viable manufacturing process due to dramatic advantages that it facilitates in the area of design complexity. This paper investigates the potential of additively manufactured lattice structures for the application of tailored impact absorption specifically for conformal body protection. It explores lattice cell types based on foam microstructures and assesses their suitability for impact absorption. The effect of varying the cell strut edge design is also investigated. The implications of scaling these cells up for AM are discussed as well as the design issues regarding the handling of geometric complexity and the requirement for body conformity. The suitability of AM materials for this application is also discussed.

  11. Additivity in the Analysis and Design of HIV Protease Inhibitors

    PubMed Central

    Jorissen, Robert N.; Kiran Kumar Reddy, G. S.; Ali, Akbar; Altman, Michael D.; Chellappan, Sripriya; Anjum, Saima G.; Tidor, Bruce; Schiffer, Celia A.; Rana, Tariq M.; Gilson, Michael K.

    2009-01-01

    We explore the applicability of an additive treatment of substituent effects to the analysis and design of HIV protease inhibitors. Affinity data for a set of inhibitors with a common chemical framework were analyzed to provide estimates of the free energy contribution of each chemical substituent. These estimates were then used to design new inhibitors, whose high affinities were confirmed by synthesis and experimental testing. Derivations of additive models by least-squares and ridge-regression methods were found to yield statistically similar results. The additivity approach was also compared with standard molecular descriptor-based QSAR; the latter was not found to provide superior predictions. Crystallographic studies of HIV protease-inhibitor complexes help explain the perhaps surprisingly high degree of substituent additivity in this system, and allow some of the additivity coefficients to be rationalized on a structural basis. PMID:19193159

  12. Hyperbolic tangential function-based progressive addition lens design.

    PubMed

    Qiu, Gufeng; Cui, Xudong

    2015-12-10

    The diopter distribution is key to the successful design of a progressive addition lens. A hyperbolic tangential function is then introduced to describe well the desired diopter distribution on the lens. Simulation and fabrication show that the astigmia on the whole surface is very close to the addition, exhibiting superior performance than that of currently used high-order polynomials and cosine functions. Our investigations found that once the diopter distribution design is reasonable, both the direct and indirect methods of constructing a progressive addition lens can give consistent results. With this function we are able to effectively control the design of critical areas, the position, sizes of far-view and near-view zones, as well as the channel of the lens. This study would provide an efficient way to customize different progressive lenses not only for presbyopia, but also for anti-fatigue, office progressive usages, etc. PMID:26836863

  13. Additive Manufacturing Design Considerations for Liquid Engine Components

    NASA Technical Reports Server (NTRS)

    Whitten, Dave; Hissam, Andy; Baker, Kevin; Rice, Darron

    2014-01-01

    The Marshall Space Flight Center's Propulsion Systems Department has gained significant experience in the last year designing, building, and testing liquid engine components using additive manufacturing. The department has developed valve, duct, turbo-machinery, and combustion device components using this technology. Many valuable lessons were learned during this process. These lessons will be the focus of this presentation. We will present criteria for selecting part candidates for additive manufacturing. Some part characteristics are 'tailor made' for this process. Selecting the right parts for the process is the first step to maximizing productivity gains. We will also present specific lessons we learned about feature geometry that can and cannot be produced using additive manufacturing machines. Most liquid engine components were made using a two-step process. The base part was made using additive manufacturing and then traditional machining processes were used to produce the final part. The presentation will describe design accommodations needed to make the base part and lessons we learned about which features could be built directly and which require the final machine process. Tolerance capabilities, surface finish, and material thickness allowances will also be covered. Additive Manufacturing can produce internal passages that cannot be made using traditional approaches. It can also eliminate a significant amount of manpower by reducing part count and leveraging model-based design and analysis techniques. Information will be shared about performance enhancements and design efficiencies we experienced for certain categories of engine parts.

  14. A Modular Aerospike Engine Design Using Additive Manufacturing

    NASA Technical Reports Server (NTRS)

    Peugeot, John; Garcia, Chance; Burkhardt, Wendel

    2014-01-01

    A modular aerospike engine concept has been developed with the objective of demonstrating the viability of the aerospike design using additive manufacturing techniques. The aerospike system is a self-compensating design that allows for optimal performance over the entire flight regime and allows for the lowest possible mass vehicle designs. At low altitudes, improvements in Isp can be traded against chamber pressure, staging, and payload. In upper stage applications, expansion ratio and engine envelope can be traded against nozzle efficiency. These features provide flexibility to the System Designer optimizing a complete vehicle stage. The aerospike concept is a good example of a component that has demonstrated improved performance capability, but traditionally has manufacturing requirements that are too expensive and complex to use in a production vehicle. In recent years, additive manufacturing has emerged as a potential method for improving the speed and cost of building geometrically complex components in rocket engines. It offers a reduction in tooling overhead and significant improvements in the integration of the designer and manufacturing method. In addition, the modularity of the engine design provides the ability to perform full scale testing on the combustion devices outside of the full engine configuration. The proposed design uses a hydrocarbon based gas-generator cycle, with plans to take advantage of existing powerhead hardware while focusing DDT&E resources on manufacturing and sub-system testing of the combustion devices. The major risks for the modular aerospike concept lie in the performance of the propellant feed system, the structural integrity of the additive manufactured components, and the aerodynamic efficiency of the exhaust flow.

  15. A kind of optimizing design method of progressive addition lenses

    NASA Astrophysics Data System (ADS)

    Tang, Yunhai; Qian, Lin; Wu, Quanying; Yu, Jingchi; Chen, Hao; Wang, Yuanyuan

    2010-10-01

    Progressive addition lenses are a kind of ophthalmic lenses with freeform surface. The surface curvature of the progressive addition lenses varies gradually from a minimum value in the upper, distance-viewing area, to a maximum value in the lower, near-viewing area. A kind of optimizing design method of progressive addition lenses is proposed to improve the optical quality by modifying the vector heights of the surface of designed progressive addition lenses initially. The relationship among mean power, cylinder power and the vector heights of the surface is deduced, and the optimizing factor is also gained. The vector heights of the surface of designed progressive addition lenses initially are used to calculate the plots of mean power and cylinder power based on the principle of differential geometry. The mean power plot is changed by adjusting the optimizing factor. Otherwise, the novel plot of the mean power can also be derived by shifting the mean power of one selected region to another and then by interpolating and smoothing. A partial differential equation of the elliptic type is founded based on the changed mean power. The solution of the equation is achieved by iterative method. The optimized vector heights of the surface are solved out. Compared with the original lens, the region in which the astigmatism near the nasal side on distance-vision portion is less than 0.5 D has become broader, and the clear regions on distance-vision and near-vision portion are wider.

  16. Courtyard Commons retail addition. Phase I. Final design documentation

    SciTech Connect

    Not Available

    1981-04-25

    The project consists of a retail addition to an existing cluster of buildings located on the main commercial street in Santa Cruz, California. The existing complex is formed by two wings of one-story buildings enclosing an open courtyard now used for circulation, a coffee shop seating area, a flower stand, and access to four retail stores. The program calls for an addition of new retail space above the existing buildings constructed of eight inch concrete blocks. In order to provide for the year around use of the courtyard, the program also calls for a flexible glass cover which could be removed during the sunny warm summer days. The main requirements of the program finally, are to develop an energy efficient and cost effective design which uses natural light at its full potential for both the courtyard and interior spaces. This report includes sections of the following: overview of final design; unavailable solar design information; incremental passive design cost, energy performance analysis and results; economic analysis and results; architectural compatibility; NBSGLD output and documentation; and design development drawings.

  17. Applying Additive Manufacturing to a New Liquid Oxygen Turbopump Design

    NASA Technical Reports Server (NTRS)

    O'Neal, Derek

    2016-01-01

    A liquid oxygen turbopump has been designed at Marshall Space Flight Center as part of the in-house, Advanced Manufacturing Demonstrator Engine (AMDE) project. Additive manufacturing, specifically direct metal laser sintering (DMLS) of Inconel 718, is used for 77% of the parts by mass. These parts include the impeller, turbine components, and housings. The near-net shape DMLS parts have been delivered and final machining is underway. Fabrication of the traditionally manufactured hardware is also proceeding. Testing in liquid oxygen is planned for Q2 of FY2017. This topic explores the design of the turbopump along with fabrication and material testing of the DMLS hardware.

  18. Progressive addition lens design by optimizing NURBS surface

    NASA Astrophysics Data System (ADS)

    Liu, Yen-Liang; Hsu, Wei-Yao; Cheng, Yuan-Chieh; Su, Guo-Dung

    2011-10-01

    Progressive addition lenses (PAL) are used to compensate presbyopia, which is induced by losing accommodation of elder eyes. These eyes need different optical power provided by eye glasses while watching objects at different distance. A smaller optical power is required in further distance and a larger one in nearer zone. A progressive addition lens can provides different power requirements in one piece of lens. This paper introduces a whole process of PAL production, from design, fabrication, to measurement. The PAL is designed by optimizing NURBS surface. Parameters of merit function are adjusted to design lenses with different specifications. The simulation results confirm that the power distributes as expected and cylinders are controlled under an acceptable level. Besides, sample lenses have been fabricated and measured. We apply precise-machining to produce the molds for plastic injection. Then, the samples are produced by injecting polycorbonate to the molds. Finally, Ultra Accuracy 3D Profilemeter is used to measure the sample PALs. Practical examinations shows that our designs are achievable and feasible in practice use.

  19. Embracing additive manufacture: implications for foot and ankle orthosis design

    PubMed Central

    2012-01-01

    Background The design of foot and ankle orthoses is currently limited by the methods used to fabricate the devices, particularly in terms of geometric freedom and potential to include innovative new features. Additive manufacturing (AM) technologies, where objects are constructed via a series of sub-millimetre layers of a substrate material, may present the opportunity to overcome these limitations and allow novel devices to be produced that are highly personalised for the individual, both in terms of fit and functionality. Two novel devices, a foot orthosis (FO) designed to include adjustable elements to relieve pressure at the metatarsal heads, and an ankle foot orthosis (AFO) designed to have adjustable stiffness levels in the sagittal plane, were developed and fabricated using AM. The devices were then tested on a healthy participant to determine if the intended biomechanical modes of action were achieved. Results The adjustable, pressure relieving FO was found to be able to significantly reduce pressure under the targeted metatarsal heads. The AFO was shown to have distinct effects on ankle kinematics which could be varied by adjusting the stiffness level of the device. Conclusions The results presented here demonstrate the potential design freedom made available by AM, and suggest that it may allow novel personalised orthotic devices to be produced which are beyond the current state of the art. PMID:22642941

  20. Additives

    NASA Technical Reports Server (NTRS)

    Smalheer, C. V.

    1973-01-01

    The chemistry of lubricant additives is discussed to show what the additives are chemically and what functions they perform in the lubrication of various kinds of equipment. Current theories regarding the mode of action of lubricant additives are presented. The additive groups discussed include the following: (1) detergents and dispersants, (2) corrosion inhibitors, (3) antioxidants, (4) viscosity index improvers, (5) pour point depressants, and (6) antifouling agents.

  1. Design and calibration of zero-additional-phase SPIDER

    SciTech Connect

    Baum, Peter; Riedle, Eberhard

    2005-09-01

    Zero-additional-phase spectral phase interferometry for direct electric field reconstruction (ZAP-SPIDER) is a novel technique for measuring the temporal shape and phase of ultrashort optical pulses directly at the interaction point of a spectroscopic experiment. The scheme is suitable for an extremely wide wavelength region from the ultraviolet to the near infrared. We present a comprehensive description of the experimental setup and design guidelines to effectively apply the technique to various wavelengths and pulse durations. The calibration of the setup and procedures to check the consistency of the measurement are discussed in detail. We show experimental data for various center wavelengths and pulse durations down to 7 fs to verify the applicability to a wide range of pulse parameters.

  2. 49 CFR 173.412 - Additional design requirements for Type A packages.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Additional design requirements for Type A packages. In addition to meeting the general design requirements... gas by chemical reaction and radiolysis. (f) The containment system will retain its...

  3. 49 CFR 173.412 - Additional design requirements for Type A packages.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Additional design requirements for Type A packages. In addition to meeting the general design requirements... gas by chemical reaction and radiolysis. (f) The containment system will retain its...

  4. 49 CFR 173.412 - Additional design requirements for Type A packages.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Additional design requirements for Type A packages. In addition to meeting the general design requirements... gas by chemical reaction and radiolysis. (f) The containment system will retain its...

  5. 49 CFR 173.412 - Additional design requirements for Type A packages.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Additional design requirements for Type A packages. In addition to meeting the general design requirements... gas by chemical reaction and radiolysis. (f) The containment system will retain its...

  6. Using Generalized Additive Models to Analyze Single-Case Designs

    ERIC Educational Resources Information Center

    Shadish, William; Sullivan, Kristynn

    2013-01-01

    Many analyses for single-case designs (SCDs)--including nearly all the effect size indicators-- currently assume no trend in the data. Regression and multilevel models allow for trend, but usually test only linear trend and have no principled way of knowing if higher order trends should be represented in the model. This paper shows how Generalized…

  7. 49 CFR 192.112 - Additional design requirements for steel pipe using alternative maximum allowable operating...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 3 2013-10-01 2013-10-01 false Additional design requirements for steel pipe...: MINIMUM FEDERAL SAFETY STANDARDS Pipe Design § 192.112 Additional design requirements for steel pipe using... segment must meet the following additional design requirements. Records for alternative MAOP must...

  8. Functional design criteria W-367, 222-S ancillary equipment addition

    SciTech Connect

    McVey, C.B.

    1995-02-21

    This paper reviews the designs and performance of tubular solid oxide fuel cells (SOFCs). A large number of tubular cells of the porous support tube type have been electrically tested, some to times over 50,000 hours; these cells have shown excellent performance and performance stability. Since 1984, successfully larger electrical generators utilizing these cells have been built and operated; a 20 kW integrated SOFC system operated for 7064 hours during 1993-1994. Results of development efforts to reduce cost and increase power output of tubular cells by eliminating porous support tube and increasing active length are described, and plans to utilize such air electrode supported cells in future SOFC systems are discussed.

  9. 77 FR 9251 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-16

    ... designate a class of employees from the Linde Ceramics Plant in Tonawanda, New York, as an addition to the... addition to the SEC: All Atomic Weapons Employees who worked in any area at the Linde Ceramics Plant...

  10. 13 CFR 108.1940 - Procedures for designation of additional Low-Income Geographic Areas

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...) as LI Areas. (b) Criteria. SBA will consider one or more of the following factors in determining whether to designate a particular census tract (or equivalent county division) as an additional LI Area... designation of an additional LI Area, SBA will publish in the Federal Register a notice that it is...

  11. 76 FR 51035 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-17

    ... HUMAN SERVICES Designation of a Class of Employees for Addition to the Special Exposure Cohort AGENCY...). ACTION: Notice. SUMMARY: HHS gives notice of a decision to designate a class of employees from Sandia National Laboratories in Albuquerque, New Mexico, as an addition to the Special Exposure Cohort (SEC)...

  12. 77 FR 32640 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-01

    ... designate a class of employees from Sandia National Laboratories in Albuquerque, New Mexico, as an addition to the Special Exposure Cohort (SEC) under the Energy Employees Occupational Illness Compensation... HUMAN SERVICES Designation of a Class of Employees for Addition to the Special Exposure Cohort...

  13. 77 FR 32641 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-01

    ... designate a class of employees from the Brookhaven National Laboratory in Upton, New York, as an addition to the Special Exposure Cohort (SEC) under the Energy Employees Occupational Illness Compensation Program... HUMAN SERVICES Designation of a Class of Employees for Addition to the Special Exposure Cohort...

  14. 75 FR 22410 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-28

    ... Livermore National Laboratory in Livermore, California, as an addition to the Special Exposure Cohort (SEC... Secretary of HHS designated the following class of employees as an addition to the SEC: All employees of the... publish a notice in the Federal Register reporting the addition of this class to the SEC or the result...

  15. 76 FR 68460 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-04

    ... Laboratory at Iowa State University as an addition to the Special Exposure Cohort (SEC) under the Energy... designated the following class of employees as an addition to the SEC: All Department of Energy (DOE... will publish a notice in the Federal Register reporting the addition of this class to the SEC or...

  16. 75 FR 22409 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-28

    ... the Santa Susana Field Laboratory as an addition to the Special Exposure Cohort (SEC) under the Energy... designated the following class of employees as an addition to the SEC: All employees of the Department of... notice in the Federal Register reporting the addition of this class to the SEC or the result of...

  17. 76 FR 68459 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-04

    ... facility in Oak Ridge, Tennessee, as an addition to the Special Exposure Cohort (SEC) under the Energy... designated the following class of employees as an addition to the SEC: All employees of the Department of... publish a notice in the Federal Register reporting the addition of this class to the SEC or the result...

  18. 75 FR 22409 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-28

    ... Berkeley National Laboratory in Berkeley, California, as an addition to the Special Exposure Cohort (SEC... Secretary of HHS designated the following class of employees as an addition to the SEC: All employees of the... will publish a notice in the Federal Register reporting the addition of this class to the SEC or...

  19. 77 FR 9250 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-16

    ... designate a class of employees from the Savannah River Site in Aiken, South Carolina, as an addition to the... contractors and subcontractors who worked at the Savannah River Site from January 1, 1953, through...

  20. 77 FR 76489 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-28

    ... designate a class of employees from the Mound Plant in Miamisburg, Ohio, as an addition to the Special... subcontractors who worked at the Mound Plant in Miamisburg, Ohio, from September 1, 1972, through December...

  1. Wood lens design philosophy based on a binary additive manufacturing technique

    NASA Astrophysics Data System (ADS)

    Marasco, Peter L.; Bailey, Christopher

    2016-04-01

    Using additive manufacturing techniques in optical engineering to construct a gradient index (GRIN) optic may overcome a number of limitations of GRIN technology. Such techniques are maturing quickly, yielding additional design degrees of freedom for the engineer. How best to employ these degrees of freedom is not completely clear at this time. This paper describes a preliminary design philosophy, including assumptions, pertaining to a particular printing technique for GRIN optics. It includes an analysis based on simulation and initial component measurement.

  2. 76 FR 63351 - Designation of Additional Individual Pursuant to Executive Order 13413

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-12

    ... Office of Foreign Assets Control Designation of Additional Individual Pursuant to Executive Order 13413... Office of Foreign Assets Control (``OFAC'') is publishing the name of one individual whose property and... designation by the Director of OFAC of the individual identified in this notice, pursuant to Executive...

  3. 76 FR 76219 - Designation of Additional Individual Pursuant to Executive Order 13413

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-06

    ... Office of Foreign Assets Control Designation of Additional Individual Pursuant to Executive Order 13413... Office of Foreign Assets Control (``OFAC'') is publishing the name of one individual whose property and... designation by the Director of OFAC of the individual identified in this notice, pursuant to Executive...

  4. 75 FR 22410 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-28

    ... Employer employees who worked at Westinghouse Electric Corp., Bloomfield, New Jersey, from August 13, 1942... HUMAN SERVICES Designation of a Class of Employees for Addition to the Special Exposure Cohort AGENCY...). ACTION: Notice. SUMMARY: HHS gives notice of a decision to designate a class of employees at...

  5. STEADY-STATE DESIGN OF VERTICAL WELLS FOR LIQUIDS ADDITION AT BIOREACTOR LANDFILLS

    EPA Science Inventory

    This paper presents design charts that a landfill engineer can use for the design of a vertical well system for liquids addition at bioreactor landfills. The flow rate and lateral and vertical zones of impact of a vertical well were estimated as a function of input variables su...

  6. 75 FR 22410 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-28

    ... Test Site as an addition to the Special Exposure Cohort (SEC) under the Energy Employees Occupational... class of employees as an addition to the SEC: All employees of the Department of Energy, its predecessor... or more other classes of employees in the SEC. This designation will become effective on May 5,...

  7. 77 FR 2545 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-18

    ... Plant in Amarillo, Texas, as an addition to the Special Exposure Cohort (SEC) under the Energy Employees... the following class of employees as an addition to the SEC: All employees of the Department of Energy... included in the SEC. This designation will become effective on January 20, 2012 unless Congress...

  8. 49 CFR 173.412 - Additional design requirements for Type A packages.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 2 2012-10-01 2012-10-01 false Additional design requirements for Type A packages. 173.412 Section 173.412 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION HAZARDOUS MATERIALS REGULATIONS SHIPPERS-GENERAL REQUIREMENTS FOR SHIPMENTS...

  9. 78 FR 50313 - Final Additional Airworthiness Design Standards: Night Visual Flight Rules (VFR) Under the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-19

    ... Code of Federal Regulations and two additional design criteria issued on September 2, 2003 (68 FR 56809... Federal Register on Friday May 31, 2013, 78 FR 32576. No comments were received, and the airworthiness... extremes, rain, fuel, oil, and solvents to which it is expected to be exposed in service and...

  10. 47 CFR 54.202 - Additional requirements for Commission designation of eligible telecommunications carriers.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 3 2014-10-01 2014-10-01 false Additional requirements for Commission designation of eligible telecommunications carriers. 54.202 Section 54.202 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) UNIVERSAL SERVICE Carriers Eligible for Universal Service Support §...

  11. 78 FR 148 - Additional Designations of Individuals Pursuant to Executive Order 13581

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-02

    ... Office of Foreign Assets Control Additional Designations of Individuals Pursuant to Executive Order 13581... Treasury's Office of Foreign Assets Control (``OFAC'') is publishing the names of three individuals whose... Director of OFAC of the five individuals identified in this notice pursuant to Executive Order 13581...

  12. 77 FR 54946 - Additional Designations of Individuals Pursuant to Executive Order 13581

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-06

    ... Office of Foreign Assets Control Additional Designations of Individuals Pursuant to Executive Order 13581... Treasury 's Office of Foreign Assets Control (``OFAC'') is publishing the names of five individuals whose... Director of OFAC of the five individuals identified in this notice pursuant to Executive Order 13581...

  13. 77 FR 54946 - Additional Designations of Individuals Pursuant to Executive Order 13581

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-06

    ... Office of Foreign Assets Control Additional Designations of Individuals Pursuant to Executive Order 13581... Treasury's Office of Foreign Assets Control (``OFAC'') is publishing the names of five individuals whose... Director of OFAC of the five individuals identified in this notice pursuant to Executive Order 13581...

  14. 47 CFR 54.202 - Additional requirements for Commission designation of eligible telecommunications carriers.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) UNIVERSAL SERVICE Carriers Eligible for Universal Service Support § 54.202 Additional requirements for Commission designation of eligible... government and tribal regulatory authority, as applicable, at the time it files its petition with the...

  15. 47 CFR 54.202 - Additional requirements for Commission designation of eligible telecommunications carriers.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) UNIVERSAL SERVICE Carriers Eligible for Universal Service Support § 54.202 Additional requirements for Commission designation of eligible... government and tribal regulatory authority, as applicable, at the time it files its petition with the...

  16. 77 FR 40059 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-06

    ... HUMAN SERVICES Designation of a Class of Employees for Addition to the Special Exposure Cohort AGENCY..., Department of Health and Human Services (HHS). ACTION: Notice. SUMMARY: HHS gives notice of a decision to... (SEC) under the Energy Employees Occupational Illness Compensation Program Act of 2000. On June...

  17. 76 FR 28436 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-17

    ... HUMAN SERVICES Designation of a Class of Employees for Addition to the Special Exposure Cohort AGENCY: National Institute for Occupational Safety and Health (NIOSH), Department of Health and Human Services (HHS...) under the Energy Employees Occupational Illness Compensation Program Act of 2000. On April 29, 2011,...

  18. 77 FR 32640 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-01

    ... HUMAN SERVICES Designation of a Class of Employees for Addition to the Special Exposure Cohort AGENCY..., Department of Health and Human Services (HHS). ACTION: Notice. SUMMARY: HHS gives notice of a decision to... the Special Exposure Cohort (SEC) under the Energy Employees Occupational Illness Compensation...

  19. 76 FR 28436 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-17

    ... Cohort (SEC) under the Energy Employees Occupational Illness Compensation Program Act of 2000. On April 29, 2011, the Secretary of HHS designated the following class of employees as an addition to the SEC... the SEC or the result of any provision by Congress regarding the decision by HHS to add the class...

  20. 78 FR 54791 - Proposed Additional Airworthiness Design Standards: Advanced Avionics Under the Special Class...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-06

    ... Regulations and two additional design criteria issued on September 2, 2003 (68 FR 56809). The regulation... 75 FR 32576. In conjunction with the expansion to Night-VFR operations intergrated avionic displays...: Advanced Avionics Under the Special Class (JAR-VLA) Regulations; Aquila Aviation by Excellence GmbH,...

  1. Just-in-time Design and Additive Manufacture of Patient-specific Medical Implants

    NASA Astrophysics Data System (ADS)

    Shidid, Darpan; Leary, Martin; Choong, Peter; Brandt, Milan

    Recent advances in medical imaging and manufacturing science have enabled the design and production of complex, patient-specific orthopaedic implants. Additive Manufacture (AM) generates three-dimensional structures layer by layer, and is not subject to the constraints associated with traditional manufacturing methods. AM provides significant opportunities for the design of novel geometries and complex lattice structures with enhanced functional performance. However, the design and manufacture of patient-specific AM implant structures requires unique expertise in handling various optimization platforms. Furthermore, the design process for complex structures is computationally intensive. The primary aim of this research is to enable the just-in-time customisation of AM prosthesis; whereby AM implant design and manufacture be completed within the time constraints of a single surgical procedure, while minimising prosthesis mass and optimising the lattice structure to match the stiffness of the surrounding bone tissue. In this research, a design approach using raw CT scan data is applied to the AM manufacture of femoral prosthesis. Using the proposed just-in-time concept, the mass of the prosthesis was rapidly designed and manufactured while satisfying the associated structural requirements. Compressive testing of lattice structures manufactured using proposed method shows that the load carrying capacity of the resected composite bone can be recovered by up to 85% and the compressive stiffness of the AM prosthesis is statistically indistinguishable from the stiffness of the initial bone.

  2. Topological design and additive manufacturing of porous metals for bone scaffolds and orthopaedic implants: A review.

    PubMed

    Wang, Xiaojian; Xu, Shanqing; Zhou, Shiwei; Xu, Wei; Leary, Martin; Choong, Peter; Qian, M; Brandt, Milan; Xie, Yi Min

    2016-03-01

    One of the critical issues in orthopaedic regenerative medicine is the design of bone scaffolds and implants that replicate the biomechanical properties of the host bones. Porous metals have found themselves to be suitable candidates for repairing or replacing the damaged bones since their stiffness and porosity can be adjusted on demands. Another advantage of porous metals lies in their open space for the in-growth of bone tissue, hence accelerating the osseointegration process. The fabrication of porous metals has been extensively explored over decades, however only limited controls over the internal architecture can be achieved by the conventional processes. Recent advances in additive manufacturing have provided unprecedented opportunities for producing complex structures to meet the increasing demands for implants with customized mechanical performance. At the same time, topology optimization techniques have been developed to enable the internal architecture of porous metals to be designed to achieve specified mechanical properties at will. Thus implants designed via the topology optimization approach and produced by additive manufacturing are of great interest. This paper reviews the state-of-the-art of topological design and manufacturing processes of various types of porous metals, in particular for titanium alloys, biodegradable metals and shape memory alloys. This review also identifies the limitations of current techniques and addresses the directions for future investigations. PMID:26773669

  3. Topological design and additive manufacturing of porous metals for bone scaffolds and orthopaedic implants: A review.

    PubMed

    Wang, Xiaojian; Xu, Shanqing; Zhou, Shiwei; Xu, Wei; Leary, Martin; Choong, Peter; Qian, M; Brandt, Milan; Xie, Yi Min

    2016-03-01

    One of the critical issues in orthopaedic regenerative medicine is the design of bone scaffolds and implants that replicate the biomechanical properties of the host bones. Porous metals have found themselves to be suitable candidates for repairing or replacing the damaged bones since their stiffness and porosity can be adjusted on demands. Another advantage of porous metals lies in their open space for the in-growth of bone tissue, hence accelerating the osseointegration process. The fabrication of porous metals has been extensively explored over decades, however only limited controls over the internal architecture can be achieved by the conventional processes. Recent advances in additive manufacturing have provided unprecedented opportunities for producing complex structures to meet the increasing demands for implants with customized mechanical performance. At the same time, topology optimization techniques have been developed to enable the internal architecture of porous metals to be designed to achieve specified mechanical properties at will. Thus implants designed via the topology optimization approach and produced by additive manufacturing are of great interest. This paper reviews the state-of-the-art of topological design and manufacturing processes of various types of porous metals, in particular for titanium alloys, biodegradable metals and shape memory alloys. This review also identifies the limitations of current techniques and addresses the directions for future investigations.

  4. Design of additive quantum codes via the code-word-stabilized framework

    SciTech Connect

    Kovalev, Alexey A.; Pryadko, Leonid P.; Dumer, Ilya

    2011-12-15

    We consider design of the quantum stabilizer codes via a two-step, low-complexity approach based on the framework of codeword-stabilized (CWS) codes. In this framework, each quantum CWS code can be specified by a graph and a binary code. For codes that can be obtained from a given graph, we give several upper bounds on the distance of a generic (additive or nonadditive) CWS code, and the lower Gilbert-Varshamov bound for the existence of additive CWS codes. We also consider additive cyclic CWS codes and show that these codes correspond to a previously unexplored class of single-generator cyclic stabilizer codes. We present several families of simple stabilizer codes with relatively good parameters.

  5. Theoretical and experimental investigation of design for multioptical-axis freeform progressive addition lenses

    NASA Astrophysics Data System (ADS)

    Xiang, HuaZhong; Chen, JiaBi; Zhu, TianFen; Wei, YeFei; Fu, DongXiang

    2015-11-01

    A freeform progressive addition lens (PAL) provides a good solution to correct presbyopia and prevent juvenile myopia by distributing pupils' optical powers of distance zone, near zone, and intermediate zone and is more widely adopted in the present optometric study. However, there is still a lack of a single-optical-axis system for the design of a PAL. This paper focuses on the research for an approach for designing a freeform PAL. A multioptical-axis system based on real viewing conditions using the eyes is employed for the representation of the freeform surface. We filled small pupils in the intermediate zone as a progressive corridor and the distance- and near-vision portions were defined as the standard spherical surfaces delimited by quadratic curves. Three freeform PALs with a spherical surface as the front side and a freeform surface as the backside were designed. We demonstrate the fabrication and measurement technologies for the PAL surface using computer numerical control machine tools from Schneider Smart and a Visionix VM-2000 Lens Power Mapper. Surface power and astigmatic values were obtained. Preliminary results showed that the approach for the design and fabrication is helpful to advance the design procedure optimization and mass production of PALs in optometry.

  6. On the design of novel multifunctional materials by using particulate additives

    NASA Astrophysics Data System (ADS)

    Dunnigan, Ross Daniel

    This thesis has been organized into five chapters. The main focus of this thesis is to design novel multifunctional materials by using particulate additives. Chapter 1 is devoted to reviewing recent studies in additive manufacturing (AM) and other background information. In Chapter 2, the synthesis and characterization of novel Ti3SiC2-reinforced Zn-matrix composites is reported. During this study, all the Zn composites were hot pressed at 500°C for 5 min at a uniaxial pressure of ~150 MPa. Microstructure analysis by SEM (Scanning Electron Microscopy) and phase analysis by XRD (X-ray Diffraction) confirmed that there was minimal interfacial reaction between Ti3SiC 2 particles and the Zn matrix. The addition of Ti3SiC 2 improved the tribological performance of these composites against alumina substrates but did not have any beneficial effect on the mechanical performance. The addition of Ti3SiC2 particulates to metal and polymer matrices show interesting properties. Chapter 3 will focus on additive manufacturing of Ti3SiC2 particulates in a polymer matrix. Waste materials are a big problem in the world. Chapters 4 and 5 focus on recycling materials. The mechanical and tribological properties of the Resin-Nylon and ResinPolyester composites are reported, respectively.

  7. Designing valid and optimised standard addition calibrations: Application to the determination of anions in seawater.

    PubMed

    Rodrigues, Joana; da Silva, Ricardo J N Bettencourt; Camões, M Filomena G F C; Oliveira, Cristina M

    2015-09-01

    A strategy for designing valid standard addition calibrations and for optimising their uncertainty is presented. The design of calibrations involves the development of models of the sensitivity and precision of the instrumental signal, in a wide range of analyte concentration (or any other studied quantity), and the definition of sample dilution and standard addition procedures that allow fulfilling the assumptions of the linear unweighted regression model in, typically, a smaller range of standard addition calibrations. Calibrators are prepared by diluting the sample and adding analyte with negligible uncertainty to fit in a concentration range where signals are homoscedastic. The minimisation of the uncertainty is supported on detailed measurement uncertainty models function of the calibrators preparation procedure and of analytical instrumentation performance. The number of collected signals replicates is defined by balancing their impact on the estimated expanded uncertainty, the resources needed and the target (maximum) uncertainty for the intended use of measurements. The calibration design strategy was successfully applied to the determination of the mass concentration (mg L(-1)) of Cl(-), Br(-), NO3(-) and SO4(-2) in seawater by ion chromatography. A target expanded uncertainty of 20% was defined for the determination of Cl(-), NO3(-) and SO4(-2), or 40% for the determination of the smaller mass concentration of Br(-). The developed measurement model produced reliable predictions of the measurement uncertainty from approximate concentration of the analyte in the sample, before its accurate quantification, thus proving optimisation is effective. Predictions are more prone to the variability of the measurement uncertainty estimation if based on low number of calibrators signals. The reported relative expanded uncertainty ranged from 7.1% to 49%.

  8. Evaluation of critical materials in five additional advance design photovoltaic cells

    SciTech Connect

    Smith, S.A.; Watts, R.L.; Martin, P.; Gurwell, W.E.

    1981-02-01

    The objective of this study is to identify potential material supply constraints due to the large-scale deployment of five advanced photovoltaic (PV) cell designs, and to suggest strategies to reduce the impacts of these production capacity limitations and potential future material shortages. The Critical Materials Assessment Program (CMAP) screens the designs and their supply chains and identifies potential shortages which might preclude large-scale use of the technologies. The results of the screening of five advanced PV cell designs are presented: (1) indium phosphide/cadmium sulfide, (2) zinc phosphide, (3) cadmium telluride/cadmium sulfide, (4) copper indium selenium, and (5) cadmium selenide photoelectrochemical. Each of these five cells is screened individually assuming that they first come online in 1991, and that 25 Gwe of peak capacity is online by the year 2000. A second computer screening assumes that each cell first comes online in 1991 and that each cell has a 5 GWe of peak capacity by the year 2000, so that the total online capacity for the five cells is 25 GWe. Based on a review of the preliminary baseline screening results, suggestions were made for varying such parameters as the layer thickness, cell production processes, etc. The resulting PV cell characterizations were then screened again by the CMAP computer code. The CMAP methodology used to identify critical materials is described; and detailed characterizations of the advanced photovoltaic cell designs under investigation, descriptions of additional cell production processes, and the results are presented. (WHK)

  9. An identification method for enclosed voids restriction in manufacturability design for additive manufacturing structures

    NASA Astrophysics Data System (ADS)

    Liu, Shutian; Li, Quhao; Chen, Wenjiong; Tong, Liyong; Cheng, Gengdong

    2015-06-01

    Additive manufacturing (AM) technologies, such as selective laser sintering (SLS) and fused deposition modeling (FDM), have become the powerful tools for direct manufacturing of complex parts. This breakthrough in manufacturing technology makes the fabrication of new geometrical features and multiple materials possible. Past researches on designs and design methods often focused on how to obtain desired functional performance of the structures or parts, specific manufacturing capabilities as well as manufacturing constraints of AM were neglected. However, the inherent constraints in AM processes should be taken into account in design process. In this paper, the enclosed voids, one type of manufacturing constraints of AM, are investigated. In mathematics, enclosed voids restriction expressed as the solid structure is simplyconnected. We propose an equivalent description of simply-connected constraint for avoiding enclosed voids in structures, named as virtual temperature method (VTM). In this method, suppose that the voids in structure are filled with a virtual heating material with high heat conductivity and solid areas are filled with another virtual material with low heat conductivity. Once the enclosed voids exist in structure, the maximum temperature value of structure will be very high. Based upon this method, the simplyconnected constraint is equivalent to maximum temperature constraint. And this method can be easily used to formulate the simply-connected constraint in topology optimization. The effectiveness of this description method is illustrated by several examples. Based upon topology optimization, an example of 3D cantilever beam is used to illustrate the trade-off between manufacturability and functionality. Moreover, the three optimized structures are fabricated by FDM technology to indicate further the necessity of considering the simply-connected constraint in design phase for AM.

  10. Optimal receiver design for diffusive molecular communication with flow and additive noise.

    PubMed

    Noel, Adam; Cheung, Karen C; Schober, Robert

    2014-09-01

    In this paper, we perform receiver design for a diffusive molecular communication environment. Our model includes flow in any direction, sources of information molecules in addition to the transmitter, and enzymes in the propagation environment to mitigate intersymbol interference. We characterize the mutual information between receiver observations to show how often independent observations can be made. We derive the maximum likelihood sequence detector to provide a lower bound on the bit error probability. We propose the family of weighted sum detectors for more practical implementation and derive their expected bit error probability. Under certain conditions, the performance of the optimal weighted sum detector is shown to be equivalent to a matched filter. Receiver simulation results show the tradeoff in detector complexity versus achievable bit error probability, and that a slow flow in any direction can improve the performance of a weighted sum detector.

  11. Biomechanical investigation into the structural design of porous additive manufactured cages using numerical and experimental approaches.

    PubMed

    Tsai, Pei-I; Hsu, Ching-Chi; Chen, San-Yuan; Wu, Tsung-Han; Huang, Chih-Chieh

    2016-09-01

    Traditional solid cages have been widely used in posterior lumbar interbody fusion (PLIF) surgery. However, solid cages significantly affect the loading mechanism of the human spine due to their extremely high structural stiffness. Previous studies proposed and investigated porous additive manufactured (AM) cages; however, their biomechanical performances were analyzed using oversimplified bone-implant numerical models. Thus, the aim of this study was to investigate the outer shape and inner porous structure of the AM cages. The outer shape of the AM cages was discovered using a simulation-based genetic algorithm; their inner porous structure was subsequently analyzed parametrically using T10-S1 multilevel spine models. Finally, six types of the AM cages, which were manufactured using selective laser melting, were tested to validate the numerical outcomes. The subsidence resistance of the optimum design was superior to the conventional cage designs. A porous AM cage with a pillar diameter of 0.4mm, a pillar angle of 40°, and a porosity of between 69% and 80% revealed better biomechanical performances. Both the numerical and experimental outcomes can help surgeons to understand the biomechanics of PLIF surgery combined with the use of AM cages. PMID:27392226

  12. Design of a mechanical system in gait rehabilitation with progressive addition of weight

    NASA Astrophysics Data System (ADS)

    Braidot, Ariel A. A.; Aleman, Guillermo L.

    2011-12-01

    In this paper we designed and developed a mechanical device for gait rehabilitation based on the application of "partial body weight reduction therapy". An evaluation of the characteristics of devices based on this therapy currently available on the market was carried out obtaining information of the different mechanisms used in it. The device was designed to adapt to different height and weight of patients and to be used with additional equipment in gait rehabilitation, for example, treadmills, elliptical trainers and vertical scalers. It was envisaged to be used by patients with asymmetry in the lower extremities capabilities. We developed a stable structure in steel ASTM A36 which does not depend on the building conditions of the installation site. RamAdvanse software was used to calculate structural stability. A winch with automatic brake mechanism was used to raise/lower the patient, who was tied to a comfortable harness which provided safety to the patient and therapist. It was possible to quantify precisely, using counterweights, the weight borne by the patient during therapy. We obtained a small-sized and ergonomic low-cost prototype, with similar features to those currently considered cutting-edge devices.

  13. Towards the design of new and improved drilling fluid additives using molecular dynamics simulations.

    PubMed

    Anderson, Richard L; Greenwel, H Christopher; Suter, James L; Jarvis, Rebecca M; Coveney, Peter V

    2010-03-01

    During exploration for oil and gas, a technical drilling fluid is used to lubricate the drill bit, maintain hydrostatic pressure, transmit sensor readings, remove rock cuttings and inhibit swelling of unstable clay based reactive shale formations. Increasing environmental awareness and resulting legislation has led to the search for new, improved biodegradable drilling fluid components. In the case of additives for clay swelling inhibition, an understanding of how existing effective additives interact with clays must be gained to allow the design of improved molecules. Owing to the disordered nature and nanoscopic dimension of the interlayer pores of clay minerals, computer simulations have become an increasingly useful tool for studying clay-swelling inhibitor interactions. In this work we briefly review the history of the development of technical drilling fluids, the environmental impact of drilling fluids and the use of computer simulations to study the interactions between clay minerals and swelling inhibitors. We report on results from some recent large-scale molecular dynamics simulation studies on low molecular weight water-soluble macromolecular inhibitor molecules. The structure and interactions of poly(propylene oxide)-diamine, poly(ethylene glycol) and poly(ethylene oxide)-diacrylate inhibitor molecules with montmorillonite clay are studied.

  14. Cloud-Based Automated Design and Additive Manufacturing: A Usage Data-Enabled Paradigm Shift.

    PubMed

    Lehmhus, Dirk; Wuest, Thorsten; Wellsandt, Stefan; Bosse, Stefan; Kaihara, Toshiya; Thoben, Klaus-Dieter; Busse, Matthias

    2015-12-19

    Integration of sensors into various kinds of products and machines provides access to in-depth usage information as basis for product optimization. Presently, this large potential for more user-friendly and efficient products is not being realized because (a) sensor integration and thus usage information is not available on a large scale and (b) product optimization requires considerable efforts in terms of manpower and adaptation of production equipment. However, with the advent of cloud-based services and highly flexible additive manufacturing techniques, these obstacles are currently crumbling away at rapid pace. The present study explores the state of the art in gathering and evaluating product usage and life cycle data, additive manufacturing and sensor integration, automated design and cloud-based services in manufacturing. By joining and extrapolating development trends in these areas, it delimits the foundations of a manufacturing concept that will allow continuous and economically viable product optimization on a general, user group or individual user level. This projection is checked against three different application scenarios, each of which stresses different aspects of the underlying holistic concept. The following discussion identifies critical issues and research needs by adopting the relevant stakeholder perspectives.

  15. Cloud-Based Automated Design and Additive Manufacturing: A Usage Data-Enabled Paradigm Shift

    PubMed Central

    Lehmhus, Dirk; Wuest, Thorsten; Wellsandt, Stefan; Bosse, Stefan; Kaihara, Toshiya; Thoben, Klaus-Dieter; Busse, Matthias

    2015-01-01

    Integration of sensors into various kinds of products and machines provides access to in-depth usage information as basis for product optimization. Presently, this large potential for more user-friendly and efficient products is not being realized because (a) sensor integration and thus usage information is not available on a large scale and (b) product optimization requires considerable efforts in terms of manpower and adaptation of production equipment. However, with the advent of cloud-based services and highly flexible additive manufacturing techniques, these obstacles are currently crumbling away at rapid pace. The present study explores the state of the art in gathering and evaluating product usage and life cycle data, additive manufacturing and sensor integration, automated design and cloud-based services in manufacturing. By joining and extrapolating development trends in these areas, it delimits the foundations of a manufacturing concept that will allow continuous and economically viable product optimization on a general, user group or individual user level. This projection is checked against three different application scenarios, each of which stresses different aspects of the underlying holistic concept. The following discussion identifies critical issues and research needs by adopting the relevant stakeholder perspectives. PMID:26703606

  16. Cloud-Based Automated Design and Additive Manufacturing: A Usage Data-Enabled Paradigm Shift.

    PubMed

    Lehmhus, Dirk; Wuest, Thorsten; Wellsandt, Stefan; Bosse, Stefan; Kaihara, Toshiya; Thoben, Klaus-Dieter; Busse, Matthias

    2015-01-01

    Integration of sensors into various kinds of products and machines provides access to in-depth usage information as basis for product optimization. Presently, this large potential for more user-friendly and efficient products is not being realized because (a) sensor integration and thus usage information is not available on a large scale and (b) product optimization requires considerable efforts in terms of manpower and adaptation of production equipment. However, with the advent of cloud-based services and highly flexible additive manufacturing techniques, these obstacles are currently crumbling away at rapid pace. The present study explores the state of the art in gathering and evaluating product usage and life cycle data, additive manufacturing and sensor integration, automated design and cloud-based services in manufacturing. By joining and extrapolating development trends in these areas, it delimits the foundations of a manufacturing concept that will allow continuous and economically viable product optimization on a general, user group or individual user level. This projection is checked against three different application scenarios, each of which stresses different aspects of the underlying holistic concept. The following discussion identifies critical issues and research needs by adopting the relevant stakeholder perspectives. PMID:26703606

  17. 77 FR 38835 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-29

    ... HUMAN SERVICES Final Effect of Designation of a Class of Employees for Addition to the Special Exposure... notice concerning the final effect of the HHS decision to designate a class of employees from the Brookhaven National Laboratory in Upton, New York, as an addition to the Special Exposure Cohort (SEC)...

  18. 77 FR 38835 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-29

    ... HUMAN SERVICES Final Effect of Designation of a Class of Employees for Addition to the Special Exposure... notice concerning the final effect of the HHS decision to designate a class of employees from the Electro Metallurgical site in Niagara Falls, New York, as an addition to the Special Exposure Cohort (SEC) under...

  19. 77 FR 38835 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-29

    ... HUMAN SERVICES Final Effect of Designation of a Class of Employees for Addition to the Special Exposure... notice concerning the final effect of the HHS decision to designate a class of employees from the Sandia National Laboratories in Albuquerque, New Mexico, as an addition to the Special Exposure Cohort (SEC)...

  20. Extracellular matrix protein in calcified endoskeleton: a potential additive for crystal growth and design

    NASA Astrophysics Data System (ADS)

    Azizur Rahman, M.; Fujimura, Hiroyuki; Shinjo, Ryuichi; Oomori, Tamotsu

    2011-06-01

    In this study, we demonstrate a key function of extracellular matrix proteins (ECMPs) on seed crystals, which are isolated from calcified endoskeletons of soft coral and contain only CaCO 3 without any living cells. This is the first report that an ECMP protein extracted from a marine organism could potentially influence in modifying the surface of a substrate for designing materials via crystallization. We previously studied with the ECMPs from a different type of soft coral ( Sinularia polydactyla) without introducing any seed crystals in the process , which showed different results. Thus, crystallization on the seed in the presence of ECMPs of present species is an important first step toward linking function to individual proteins from soft coral. For understanding this interesting phenomenon, in vitro crystallization was initiated in a supersaturated solution on seed particles of calcite (1 0 4) with and without ECMPs. No change in the crystal growth shape occurred without ECMPs present during the crystallization process. However, with ECMPs, the morphology and phase of the crystals in the crystallization process changed dramatically. Upon completion of crystallization with ECMPs, an attractive crystal morphology was found. Scanning electron microscopy (SEM) was utilized to observe the crystal morphologies on the seeds surface. The mineral phases of crystals nucleated by ECMPs on the seeds surface were examined by Raman spectroscopy. Although 50 mM Mg 2+ is influential in making aragonite in the crystallization process, the ECMPs significantly made calcite crystals even when 50 mM Mg 2+ was present in the process. Crystallization with the ECMP additive seems to be a technically attractive strategy to generate assembled micro crystals that could be used in crystals growth and design in the Pharmaceutical and biotechnology industries.

  1. Additive Manufacturing, Design, Testing, and Fabrication: A Full Engineering Experience at JSC

    NASA Technical Reports Server (NTRS)

    Zusack, Steven

    2016-01-01

    I worked on several projects this term. While most projects involved additive manufacturing, I was also involved with two design projects, two testing projects, and a fabrication project. The primary mentor for these was Richard Hagen. Secondary mentors were Hai Nguyen, Khadijah Shariff, and fabrication training from James Brown. Overall, my experience at JSC has been successful and what I have learned will continue to help me in my engineering education and profession long after I leave. My 3D printing projects ranged from less than a 1 cubic centimeter to about 1 cubic foot and involved several printers using different printing technologies. It was exciting to become familiar with printing technologies such as industrial grade FDM (Fused Deposition Modeling), the relatively new SLA (Stereolithography), and PolyJet. My primary duty with the FDM printers was to model parts that came in from various sources to print effectively and efficiently. Using methods my mentor taught me and the Stratasys Insight software, I was able to minimize imperfections, hasten build time, improve strength for specific forces (tensile, shear, etc...), and reduce likelihood of a print-failure. Also using FDM, I learned how to repair a part after it was printed. This is done by using a special kind of glue that chemically melts the two faces of plastic parts together to form a fused interface. My first goal with SLA technology was to bring the printer back to operational readiness. In becoming familiar with the Pegasus SLA printer, I researched the leveling, laser settings, and different vats to hold liquid material. With this research, I was successfully able to bring the Pegasus back online and have successfully printed multiple sample parts as well as functional parts. My experience with PolyJet technology has been focused on an understanding of the abilities/limits, costs, and the maintenance for daily use. Still upcoming will be experience with using a composite printer that uses FDM

  2. Automated microbial metabolism laboratory. [design of advanced labeled release experiment based on single addition of soil and multiple sequential additions of media into test chambers

    NASA Technical Reports Server (NTRS)

    1974-01-01

    The design and rationale of an advanced labeled release experiment based on single addition of soil and multiple sequential additions of media into each of four test chambers are outlined. The feasibility for multiple addition tests was established and various details of the methodology were studied. The four chamber battery of tests include: (1) determination of the effect of various atmospheric gases and selection of that gas which produces an optimum response; (2) determination of the effect of incubation temperature and selection of the optimum temperature for performing Martian biochemical tests; (3) sterile soil is dosed with a battery of C-14 labeled substrates and subjected to experimental temperature range; and (4) determination of the possible inhibitory effects of water on Martian organisms is performed initially by dosing with 0.01 ml and 0.5 ml of medium, respectively. A series of specifically labeled substrates are then added to obtain patterns in metabolic 14CO2 (C-14)O2 evolution.

  3. 76 FR 33762 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-09

    ... decision to designate a class of employees from the Wah Chang facility, Albany, Oregon, as an addition to... who worked in any building at the Wah Chang facility in Albany, Oregon, for the operational...

  4. 78 FR 64500 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-29

    ... addition to the Special Exposure Cohort (SEC) under the Energy Employees Occupational Illness Compensation... employees as an addition to the SEC: All employees of the Feed Materials Production Center (FMPC) in Fernald... notice in the Federal Register reporting the addition of this class to the SEC or the result of...

  5. 75 FR 44968 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-30

    ..., New Mexico, as an addition to the Special Exposure Cohort (SEC) under the Energy Employees... following class of employees as an addition to the SEC: All employees of the Department of Energy, its... Register reporting the addition of this class to the SEC or the result of any provision by...

  6. 78 FR 77685 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-24

    ... an addition to the Special Exposure Cohort (SEC) under the Energy Employees Occupational Illness... employees as an addition to the SEC: ] All employees of the Department of Energy, its predecessor agencies... notice in the Federal Register reporting the addition of this class to the SEC or the result of...

  7. 78 FR 64501 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-29

    ... addition to the Special Exposure Cohort (SEC) under the Energy Employees Occupational Illness Compensation... employees as an addition to the SEC: All employees of the Department of Energy, its predecessor agencies... Register reporting the addition of this class to the SEC or the result of any provision by...

  8. 75 FR 44968 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-30

    ..., Missouri, as an addition to the Special Exposure Cohort (SEC) under the Energy Employees Occupational... class of employees as an addition to the SEC: All employees of the Department of Energy, its predecessor... publish a notice in the Federal Register reporting the addition of this class to the SEC or the result...

  9. 75 FR 44966 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-30

    ... County, California, as an addition to the Special Exposure Cohort (SEC) under the Energy Employees... following class of employees as an addition to the SEC: All employees of the Department of Energy, its... Federal Register reporting the addition of this class to the SEC or the result of any provision...

  10. 75 FR 44966 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-30

    ... York, as an addition to the Special Exposure Cohort (SEC) under the Energy Employees Occupational... class of employees as an addition to the SEC: All Atomic Weapons Employer employees who worked at the... publish a notice in the Federal Register reporting the addition of this class to the SEC or the result...

  11. 78 FR 21954 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-12

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Final Effect of Designation of a Class of Employees for Addition to the Special Exposure... notice concerning the final effect of the HHS decision to designate a class of employees from...

  12. 78 FR 70949 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-27

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Final Effect of Designation of a Class of Employees for Addition to the Special Exposure... notice concerning the final effect of the HHS decision to designate a class of employees from the...

  13. 77 FR 60437 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-03

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Final Effect of Designation of a Class of Employees for Addition to the Special Exposure... notice concerning the final effect of the HHS decision to designate a class of employees from the...

  14. 75 FR 3470 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-21

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Final Effect of Designation of a Class of Employees for Addition to the Special Exposure... notice concerning the final effect of the HHS decision to designate a class of employees at...

  15. 77 FR 38834 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-29

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Final Effect of Designation of a Class of Employees for Addition to the Special Exposure... notice concerning the final effect of the HHS decision to designate a class of employees from...

  16. 78 FR 3897 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-17

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Final Effect of Designation of a Class of Employees for Addition to the Special Exposure... notice concerning the final effect of the HHS decision to designate a class of employees from the...

  17. 75 FR 37812 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-30

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Final Effect of Designation of a Class of Employees for Addition to the Special Exposure... notice concerning the final effect of the HHS decision to designate a class of employees at the...

  18. 78 FR 21954 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-12

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Final Effect of Designation of a Class of Employees for Addition to the Special Exposure... notice concerning the final effect of the HHS decision to designate a class of employees from the...

  19. 77 FR 46438 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-03

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Final Effect of Designation of a Class of Employees for Addition to the Special Exposure... notice concerning the final effect of the HHS decision to designate a class of employees from the...

  20. 77 FR 15759 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-16

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Final Effect of Designation of a Class of Employees for Addition to the Special Exposure... notice concerning the final effect of the HHS decision to designate a class of employees from...

  1. 75 FR 3469 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-21

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Final Effect of Designation of a Class of Employees for Addition to the Special Exposure... notice concerning the final effect of the HHS decision to designate a class of employees at the...

  2. 78 FR 3898 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-17

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Final Effect of Designation of a Class of Employees for Addition to the Special Exposure... notice concerning the final effect of the HHS decision to designate a class of employees from Oak...

  3. 77 FR 60438 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-03

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Final Effect of Designation of a Class of Employees for Addition to the Special Exposure... notice concerning the final effect of the HHS decision to designate a class of employees from...

  4. 78 FR 3898 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-17

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF HEALTH AND HUMAN SERVICES Final Effect of Designation of a Class of Employees for Addition to the Special Exposure... notice concerning the final effect of the HHS decision to designate a class of employees from the...

  5. 78 FR 21955 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-12

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Final Effect of Designation of a Class of Employees for Addition to the Special Exposure... notice concerning the final effect of the HHS decision to designate a class of employees from the...

  6. 77 FR 69845 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-21

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Final Effect of Designation of a Class of Employees for Addition to the Special Exposure... notice concerning the final effect of the HHS decision to designate a class of employees from the...

  7. 75 FR 51817 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-23

    ... HUMAN SERVICES National Institute for Occupational Safety and Health Final Effect of Designation of a...: HHS gives notice concerning the final effect of the HHS decision to designate a class of employees from BWX Technologies, Inc., in Lynchburg, Virginia, as an addition to the Special Exposure Cohort...

  8. 77 FR 58382 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-20

    ... designate a class of employees from Winchester Engineering and Analytical Center in Winchester... Analytical Center in Winchester, Massachusetts, from January 1, 1952, through December 31, 1961, for a...

  9. Modeling Longitudinal Data with Generalized Additive Models: Applications to Single-Case Designs

    ERIC Educational Resources Information Center

    Sullivan, Kristynn J.; Shadish, William R.

    2013-01-01

    Single case designs (SCDs) are short time series that assess intervention effects by measuring units repeatedly over time both in the presence and absence of treatment. For a variety of reasons, interest in the statistical analysis and meta-analysis of these designs has been growing in recent years. This paper proposes modeling SCD data with…

  10. 77 FR 76490 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-28

    ... designate a class of employees from the Oak Ridge National Laboratory (X-10) in Oak Ridge, Tennessee, as an... Program Act of 2000. On December 7, 2012, the Secretary of HHS designated the following class of employees... their contractors and subcontractors who worked in any area at the Oak Ridge National Laboratory...

  11. 75 FR 44966 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-30

    ..., as an addition to the Special Exposure Cohort (SEC) under the Energy Employees Occupational Illness... employees as an addition to the SEC: All Atomic Weapons Employer employees who worked at BWX Technologies... class to the SEC or the result of any provision by Congress regarding the decision by HHS to add...

  12. 77 FR 58382 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-20

    ... Special Exposure Cohort (SEC) under the Energy Employees Occupational Illness Compensation Program Act of... addition to the SEC: All employees of the Department of Energy, its predecessor agencies, and their... addition of this class to the SEC or the result of any provision by Congress regarding the decision by...

  13. 77 FR 64996 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-24

    ... the Special Exposure Cohort (SEC) under the Energy Employees Occupational Illness Compensation Program... an addition to the SEC: All Atomic Weapons Employees who worked for the Ventron Corporation at its... publish a notice in the Federal Register reporting the addition of this class to the SEC or the result...

  14. 78 FR 18351 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-26

    ... designate a class of employees from the Battelle Laboratories King Avenue facility in Columbus, Ohio, as an... Battelle Laboratories in Columbus, Ohio, during the period from April 16, 1943, through June 30, 1956,...

  15. 77 FR 58381 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-20

    ... designate a class of employees from Clarksville Modification Center, Ft. Campbell, in Clarksville, Tennessee... Campbell, in Clarksville, Tennessee, from August 1, 1949, through December 31, 1967, for a number of...

  16. 76 FR 28435 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-17

    ...). ACTION: Notice. SUMMARY: HHS gives notice of a decision to designate a class of employees from the Vitro... Employer employees who worked at Vitro Manufacturing in Canonsburg, Pennsylvania, from January 1,...

  17. 76 FR 68459 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-04

    ...). ACTION: Notice. SUMMARY: HHS gives notice of a decision to designate a class of employees from Vitro... Employees who worked at Vitro Manufacturing in Canonsburg, Pennsylvania, from January 1, 1960...

  18. 10 CFR 60.133 - Additional design criteria for the underground facility.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... deleterious rock movement or fracturing of overlying or surrounding rock. (f) Rock excavation. The design of... creating a preferential pathway for groundwater to contact the waste packages or radionuclide migration to... rock, and surrounding strata, groundwater system....

  19. 10 CFR 60.133 - Additional design criteria for the underground facility.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... deleterious rock movement or fracturing of overlying or surrounding rock. (f) Rock excavation. The design of... creating a preferential pathway for groundwater to contact the waste packages or radionuclide migration to... rock, and surrounding strata, groundwater system....

  20. 10 CFR 60.133 - Additional design criteria for the underground facility.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... deleterious rock movement or fracturing of overlying or surrounding rock. (f) Rock excavation. The design of... creating a preferential pathway for groundwater to contact the waste packages or radionuclide migration to... rock, and surrounding strata, groundwater system....

  1. 10 CFR 60.133 - Additional design criteria for the underground facility.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... deleterious rock movement or fracturing of overlying or surrounding rock. (f) Rock excavation. The design of... creating a preferential pathway for groundwater to contact the waste packages or radionuclide migration to... rock, and surrounding strata, groundwater system....

  2. 10 CFR 60.133 - Additional design criteria for the underground facility.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... deleterious rock movement or fracturing of overlying or surrounding rock. (f) Rock excavation. The design of... creating a preferential pathway for groundwater to contact the waste packages or radionuclide migration to... rock, and surrounding strata, groundwater system....

  3. 75 FR 44967 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-30

    ... of a decision to designate a class of employees from the Mound Plant in Miamisburg, Ohio, as an... Mound Plant in Miamisburg, Ohio from March 1, 1959 through March 5, 1980, for a number of work...

  4. 76 FR 28436 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-17

    ... Chang facility in Albany, Oregon, as an addition to the Special Exposure Cohort (SEC) under the Energy... who worked in any building at the Wah Chang facility in Albany, Oregon, for the operational...

  5. 76 FR 26299 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-06

    ... Linde Ceramics Plant in Tonawanda, New York, as an addition to the Special Exposure Cohort (SEC) under... Employees who worked at the Linde Ceramics Plant in Tonawanda, New York, from January 1, 1954...

  6. 76 FR 68459 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-04

    ... and Company in Curtis Bay, Maryland, as an addition to the Special Exposure Cohort (SEC) under the... Employees who worked at any building or area at the facility owned by W.R. Grace and Company in Curtis...

  7. 76 FR 57044 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-15

    ... General Electric Co. in Evendale, Ohio, as an addition to the Special Exposure Cohort (SEC) under the... General Electric Co. in Evendale, Ohio, from January 1, 1961 through June 30, 1970, for a number of...

  8. CHARMM additive and polarizable force fields for biophysics and computer-aided drug design

    PubMed Central

    Vanommeslaeghe, K.

    2014-01-01

    Background Molecular Mechanics (MM) is the method of choice for computational studies of biomolecular systems owing to its modest computational cost, which makes it possible to routinely perform molecular dynamics (MD) simulations on chemical systems of biophysical and biomedical relevance. Scope of Review As one of the main factors limiting the accuracy of MD results is the empirical force field used, the present paper offers a review of recent developments in the CHARMM additive force field, one of the most popular bimolecular force fields. Additionally, we present a detailed discussion of the CHARMM Drude polarizable force field, anticipating a growth in the importance and utilization of polarizable force fields in the near future. Throughout the discussion emphasis is placed on the force fields’ parametrization philosophy and methodology. Major Conclusions Recent improvements in the CHARMM additive force field are mostly related to newly found weaknesses in the previous generation of additive force fields. Beyond the additive approximation is the newly available CHARMM Drude polarizable force field, which allows for MD simulations of up to 1 microsecond on proteins, DNA, lipids and carbohydrates. General Significance Addressing the limitations ensures the reliability of the new CHARMM36 additive force field for the types of calculations that are presently coming into routine computational reach while the availability of the Drude polarizable force fields offers a model that is an inherently more accurate model of the underlying physical forces driving macromolecular structures and dynamics. PMID:25149274

  9. Rational design of solution additives for the prevention of protein aggregation.

    PubMed

    Baynes, Brian M; Trout, Bernhardt L

    2004-09-01

    We have developed a statistical-mechanical model of the effect of solution additives on protein association reactions. This model incorporates solvent radial distribution functions obtained from all-atom molecular dynamics simulations of particular proteins into simple models of protein interactions. In this way, the effects of additives can be computed along the entire association/dissociation reaction coordinate. We used the model to test our hypothesis that a class of large solution additives, which we term "neutral crowders," can slow protein association and dissociation by being preferentially excluded from protein-protein encounter complexes, in a manner analogous to osmotic stress. The magnitude of this proposed "gap effect" was probed for two simple model systems: the association of two spheres and the association of two planes. Our results suggest that for a protein of 20 A radius, an 8 A additive can increase the free energy barrier for association and dissociation by as much as 3-6 kcal/mol. Because the proposed gap effect is present only for reactions involving multiple molecules, it can be exploited to develop novel additives that affect protein association reactions although having little or no effect on unimolecular reactions such as protein folding. This idea has many potential applications in areas such as the stabilization of proteins against aggregation during folding and in pharmaceutical formulations.

  10. Large Advanced Space Systems (LASS) computer-aided design program additions

    NASA Technical Reports Server (NTRS)

    Farrell, C. E.

    1982-01-01

    The LSS preliminary and conceptual design requires extensive iteractive analysis because of the effects of structural, thermal, and control intercoupling. A computer aided design program that will permit integrating and interfacing of required large space system (LSS) analyses is discussed. The primary objective of this program is the implementation of modeling techniques and analysis algorithms that permit interactive design and tradeoff studies of LSS concepts. Eight software modules were added to the program. The existing rigid body controls module was modified to include solar pressure effects. The new model generator modules and appendage synthesizer module are integrated (interfaced) to permit interactive definition and generation of LSS concepts. The mass properties module permits interactive specification of discrete masses and their locations. The other modules permit interactive analysis of orbital transfer requirements, antenna primary beam n, and attitude control requirements.

  11. 76 FR 73758 - Additional Designation of Four Entities Pursuant to Executive Order 13382

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-29

    ...: Designation of Nuclear Reactors Fuel Company (SUREH), Noor Afzar Gostar Company (NAGCO), Fulmen Group, and... determined that four Iranian entities, Nuclear Reactors Fuel Company (SUREH), Noor Afzar Gostar Company... NUCLEAR REACTORS FUEL COMPANY (a.k.a.: SUREH. Location: 61 Shahid Abtahi St., Karegar e Shomali,...

  12. 76 FR 52384 - Designation of Additional Entities Pursuant to Executive Order 13405

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-22

    ... Democratic Processes or Institutions in Belarus.'' DATES: The designation by the Director of OFAC of the four... repression, electoral fraud, and public corruption in Belarus. The Order imposes economic sanctions on persons responsible for actions or policies that undermine democratic processes or institutions in...

  13. Laser and electron-beam powder-bed additive manufacturing of metallic implants: A review on processes, materials and designs.

    PubMed

    Sing, Swee Leong; An, Jia; Yeong, Wai Yee; Wiria, Florencia Edith

    2016-03-01

    Additive manufacturing (AM), also commonly known as 3D printing, allows the direct fabrication of functional parts with complex shapes from digital models. In this review, the current progress of two AM processes suitable for metallic orthopaedic implant applications, namely selective laser melting (SLM) and electron beam melting (EBM) are presented. Several critical design factors such as the need for data acquisition for patient-specific design, design dependent porosity for osteo-inductive implants, surface topology of the implants and design for reduction of stress-shielding in implants are discussed. Additive manufactured biomaterials such as 316L stainless steel, titanium-6aluminium-4vanadium (Ti6Al4V) and cobalt-chromium (CoCr) are highlighted. Limitations and future potential of such technologies are also explored.

  14. Laser and electron-beam powder-bed additive manufacturing of metallic implants: A review on processes, materials and designs.

    PubMed

    Sing, Swee Leong; An, Jia; Yeong, Wai Yee; Wiria, Florencia Edith

    2016-03-01

    Additive manufacturing (AM), also commonly known as 3D printing, allows the direct fabrication of functional parts with complex shapes from digital models. In this review, the current progress of two AM processes suitable for metallic orthopaedic implant applications, namely selective laser melting (SLM) and electron beam melting (EBM) are presented. Several critical design factors such as the need for data acquisition for patient-specific design, design dependent porosity for osteo-inductive implants, surface topology of the implants and design for reduction of stress-shielding in implants are discussed. Additive manufactured biomaterials such as 316L stainless steel, titanium-6aluminium-4vanadium (Ti6Al4V) and cobalt-chromium (CoCr) are highlighted. Limitations and future potential of such technologies are also explored. PMID:26488900

  15. 77 FR 58911 - Additional Identifying Information for One (1) Individual Designated Pursuant to Executive Order...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-24

    ... Threaten to Disrupt the Middle East Peace Process'' (the ``Order''). DATES: The addition by the Director of... sanctions on persons who threaten to disrupt the Middle East peace process. The President identified in the... Middle East peace ] process; or (2) assist in, sponsor, or provide financial, material, or...

  16. Designing Location-Based Learning Experiences for People with Intellectual Disabilities and Additional Sensory Impairments

    ERIC Educational Resources Information Center

    Brown, David J.; McHugh, David; Standen, Penny; Evett, Lindsay; Shopland, Nick; Battersby, Steven

    2011-01-01

    The research reported here is part of a larger project which seeks to combine serious games (or games-based learning) with location-based services to help people with intellectual disabilities and additional sensory impairments to develop work based skills. Specifically this paper reports on where these approaches are combined to scaffold the…

  17. 77 FR 58382 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-20

    ... Special Exposure Cohort (SEC) under the Energy Employees Occupational Illness Compensation Program Act of... addition to the SEC: All employees of the Department of Energy, its predecessor agencies, and their... this class to the SEC or the result of any provision by Congress regarding the decision by HHS to...

  18. 78 FR 77686 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-24

    ... Exposure Cohort (SEC) under the Energy Employees Occupational Illness Compensation Program Act of 2000. On... SEC: All employees of the Department of Energy, its predecessor agencies, and their contractors and..., HHS will publish a notice in the Federal Register reporting the addition of this class to the SEC...

  19. 78 FR 64501 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-29

    ... Exposure Cohort (SEC) under the Energy Employees Occupational Illness Compensation Program Act of 2000. On... SEC: All employees of the Department of Energy, its predecessor agencies, and their contractors and... date, HHS will publish a notice in the Federal Register reporting the addition of this class to the...

  20. Additional F-Functions Useful for Preliminary Design of Shaped-Signature, Low-Boom, Supersonic-Cruise Aircraft

    NASA Technical Reports Server (NTRS)

    Mack, Robert J.

    1999-01-01

    Two additional low-boom F-functions have been described for use in designing low-boom, shaped-pressure-signature, supersonic-cruise aircraft. Based on the minimization studies of Seebass and George, the drag-nose shock strength trade-off modification of Darden, and the practical modification of Haglund, their use can aid in the design of conceptual low-boom aircraft, provide additional flexibility in the shaping of the low-boom aircraft nose section, and extend the applicability of shaped-pressure-signature methodology.

  1. Design of a Soil Science practical exercise to understand the soil carbon sequestration after biochar addition

    NASA Astrophysics Data System (ADS)

    Gascó, Gabriel; Cely, Paola; Saa-Requejo, Antonio; Mendez, Ana; Antón, Jose Manuel; Sánchez, Elena; Moratiel, Ruben; Tarquis, Ana M.

    2014-05-01

    The adaptation of the Universities to European Higher Education Area (EHEA) involves changes in the learning system. Students must obtain specific capabilities in the different degrees or masters. For example, in the degree of Agronomy at the Universidad Politécnica de Madrid (UPM, Spain), they must command Soil science, Mathematics or English. Sometimes, There is not a good communication between teachers and it causes that students do not understand the importance of the different subjects of a career. For this reason, teachers of the Soil Science and Mathematics Departments of the UPM designed a common practice to teach to the students the role of soil on the carbon sequestration. The objective of this paper is to explain the followed steps to the design of the practice. Acknowledgement to Universidad Politécnica de Madrid for the Projects in Education Innovation IE12_13-02009 and IE12_13-02012.

  2. Targeted gene addition into a specified location in the human genome using designed zinc finger nucleases

    PubMed Central

    Moehle, Erica A.; Rock, Jeremy M.; Lee, Ya-Li; Jouvenot, Yann; DeKelver, Russell C.; Gregory, Philip D.; Urnov, Fyodor D.; Holmes, Michael C.

    2007-01-01

    Efficient incorporation of novel DNA sequences into a specific site in the genome of living human cells remains a challenge despite its potential utility to genetic medicine, biotechnology, and basic research. We find that a precisely placed double-strand break induced by engineered zinc finger nucleases (ZFNs) can stimulate integration of long DNA stretches into a predetermined genomic location, resulting in high-efficiency site-specific gene addition. Using an extrachromosomal DNA donor carrying a 12-bp tag, a 900-bp ORF, or a 1.5-kb promoter-transcription unit flanked by locus-specific homology arms, we find targeted integration frequencies of 15%, 6%, and 5%, respectively, within 72 h of treatment, and with no selection for the desired event. Importantly, we find that the integration event occurs in a homology-directed manner and leads to the accurate reconstruction of the donor-specified genotype at the endogenous chromosomal locus, and hence presumably results from synthesis-dependent strand annealing repair of the break using the donor DNA as a template. This site-specific gene addition occurs with no measurable increase in the rate of random integration. Remarkably, we also find that ZFNs can drive the addition of an 8-kb sequence carrying three distinct promoter-transcription units into an endogenous locus at a frequency of 6%, also in the absence of any selection. These data reveal the surprising versatility of the specialized polymerase machinery involved in double-strand break repair, illuminate a powerful approach to mammalian cell engineering, and open the possibility of ZFN-driven gene addition therapy for human genetic disease. PMID:17360608

  3. Novel Overhang Support Designs for Powder-Based Electron Beam Additive Manufacturing (EBAM)

    NASA Technical Reports Server (NTRS)

    Nabors, Sammy A.

    2014-01-01

    NASA Marshall Space Flight Center, in collaboration with the University of Alabama, has developed a contact-free support structure used to fabricate overhang-type geometries via EBAM. The support structure is used for 3-D metal-printed components for the aerospace, automotive, biomedical and other industries. Current techniques use support structures to address deformation challenges inherent in 3-D metal printing. However, these structures (overhangs) are bonded to the component and need to be removed in post-processing using a mechanical tool. This new technology improves the overhang support structure design for components by eliminating associated geometric defects and post-processing requirements.

  4. 10 CFR 60.132 - Additional design criteria for surface facilities in the geologic repository operations area.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... the Geologic Repository Operations Area § 60.132 Additional design criteria for surface facilities in the geologic repository operations area. (a) Facilities for receipt and retrieval of waste. Surface... wastes at the geologic repository operations area, whether these wastes are on the surface...

  5. Testing for Additivity in Chemical Mixtures Using a Fixed-Ratio Ray Design and Statistical Equivalence Testing Methods

    EPA Science Inventory

    Fixed-ratio ray designs have been used for detecting and characterizing interactions of large numbers of chemicals in combination. Single chemical dose-response data are used to predict an “additivity curve” along an environmentally relevant ray. A “mixture curve” is estimated fr...

  6. 76 FR 72929 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-28

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF HEALTH AND HUMAN SERVICES Final Effect of Designation of a Class of Employees for Addition to the Special Exposure... Human Services (HHS). ACTION: Notice. SUMMARY: HHS gives notice concerning the final effect of the...

  7. 75 FR 27784 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-18

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Final Effect of Designation of a Class of Employees for Addition to the Special Exposure... Human Services (HHS). ACTION: Notice. SUMMARY: HHS gives notice concerning the final effect of...

  8. 75 FR 67364 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-02

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Final Effect of Designation of a Class of Employees for Addition to the Special Exposure... Human Services (HHS). ACTION: Notice. SUMMARY: HHS gives notice concerning the final effect of the...

  9. 75 FR 27785 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-18

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Final Effect of Designation of a Class of Employees for Addition to the Special Exposure... Human Services (HHS). ACTION: Notice. SUMMARY: HHS gives notice concerning the final effect of...

  10. 76 FR 34074 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-10

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Final Effect of Designation of a Class of Employees for Addition to the Special Exposure... Human Services (HHS). ACTION: Notice. SUMMARY: HHS gives notice concerning the final effect of the...

  11. 76 FR 7852 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-11

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Final Effect of Designation of a Class of Employees for Addition to the Special Exposure... Human Services (HHS). ACTION: Notice. SUMMARY: HHS gives notice concerning the final effect of the...

  12. 76 FR 59701 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-27

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Final Effect of Designation of a Class of Employees for Addition to the Special Exposure... Human Services (HHS). ACTION: Notice. SUMMARY: HHS gives notice concerning the final effect of the...

  13. 76 FR 33763 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-09

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Final Effect of Designation of a Class of Employees for Addition to the Special Exposure... Human Services (HHS). ACTION: Notice. SUMMARY: HHS gives notice concerning the final effect of the...

  14. 40 CFR 267.1103 - What additional design and operating standards apply if liquids will be in my containment building?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 27 2014-07-01 2014-07-01 false What additional design and operating standards apply if liquids will be in my containment building? 267.1103 Section 267.1103 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR OWNERS...

  15. DETERMINING A ROBUST D-OPTIMAL DESIGN FOR TESTING FOR DEPARTURE FROM ADDITIVITY IN A MIXTURE OF FOUR PFAAS

    EPA Science Inventory

    Our objective was to determine an optimal experimental design for a mixture of perfluoroalkyl acids (PFAAs) that is robust to the assumption of additivity. Of particular focus to this research project is whether an environmentally relevant mixture of four PFAAs with long half-liv...

  16. Determining a Robust D-Optimal Design for Testing for Departure from Additivity in a Mixture of Four Perfluoroalkyl Acids.

    EPA Science Inventory

    Our objective is to determine an optimal experimental design for a mixture of perfluoroalkyl acids (PFAAs) that is robust to the assumption of additivity. PFAAs are widely used in consumer products and industrial applications. The presence and persistence of PFAAs, especially in ...

  17. 78 FR 3897 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-17

    ... Cohort AGENCY: National Institute for Occupational Safety and Health (NIOSH), Centers for Disease Control... notice concerning the final effect of the HHS decision to designate a class of employees from the Nuclear... employees as an addition to the SEC: All Atomic Weapons Employees who worked at the facility owned...

  18. Additional testing of the inlets designed for a tandem fan V/STOL nacelle

    NASA Technical Reports Server (NTRS)

    Ybarra, A. H.

    1981-01-01

    The wind tunnel testing of a scale model of a tandem fan nacelle designed for a type (subsonic cruise) V/STOL aircraft configuration is discussed. The performance for the isolated front inlet and for the combined front and aft inlets is reported. Model variables include front and aft inlets with aft inlet variations of short and long aft inlet cowls, with a shaft simulator and diffuser vortex generators, cowl lip fillets, and nacelle strakes. Inlet pressure recovery, distortion, and inlet angle-to-attack separation limits were evaluated at tunnel velocity from 0 to 240 knots, angles-of-attack from -10 to +40 degrees and inlet flow rates corresponding to throat Mach number from 0.0 to 0.6. Combined nacelle pitch and yaw runs up to 30 deg. were also made.

  19. 75 FR 3469 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-21

    ...The Department of Health and Human Services (HHS) gives notice concerning the final effect of the HHS decision to designate a class of employees at the Hanford site in Richland, Washington, as an addition to the Special Exposure Cohort (SEC) under the Energy Employees Occupational Illness Compensation Program Act of 2000. On December 10, 2009, as provided for under 42 U.S.C. 7384q(b), the......

  20. Effect of low-addition soft contact lenses with decentered optical design on myopia progression in children: a pilot study

    PubMed Central

    Fujikado, Takashi; Ninomiya, Sayuri; Kobayashi, Takuma; Suzaki, Asaki; Nakada, Mitsuhiko; Nishida, Kohji

    2014-01-01

    Purpose To investigate the effect of low-addition soft contact lenses (CLs) with decentered optical design on the progression of myopia in children in a pilot study. Subjects and methods Twenty-four Japanese children age 10–16 years with baseline myopia of −0.75 to −3.50 D sphere and ≤1.00 D cylinder were studied. The new CLs were designed to have a nasal decentration with the optical center centered on the line of sight, and with progressive-addition power of +0.5 D peripherally. Monofocal soft CLs were used as controls. A pair of new CLs or control CLs was randomly assigned to the children, and they wore the lenses for 12 months during the first phase. Then, the type of CLs was changed, ie, a crossover design, and the children were observed for another 12 months during the second phase. The end points were changes in axial length and refractive error (spherical equivalent) under cycloplegia. Results The change of axial length in the new-CL and control-CL groups was not different between 12 months and baseline, the change of axial length between 12 months and 1 month in the new-CL group (0.09±0.08 mm) was significantly smaller (47%) than that in the control-CL group (0.17±0.08 mm, P<0.05). During the same period, the change of refractive error in the new-CL group was not significantly different from that in the control group. Neither the change in axial length nor refractive error in the new-CL group was significantly different from those in the control-CL group in the second phase. Conclusion This pilot study suggests that low-addition soft CLs with decentered optical design can reduce the degree of axial elongation in myopic children after an initial transient phase of CL wear. The reduction of the progression of myopia by low-addition soft CLs warrants further investigations. PMID:25284981

  1. Effect of Additives on Green Sand Molding Properties using Design of Experiments and Taguchi's Quality Loss Function - An Experimental Study

    NASA Astrophysics Data System (ADS)

    Desai, Bhagyashree; Mokashi, Pavani; Anand, R. L.; Burli, S. B.; Khandal, S. V.

    2016-09-01

    The experimental study aims to underseek the effect of various additives on the green sand molding properties as a particular combination of additives could yield desired sand properties. The input parameters (factors) selected were water and powder (Fly ash, Coconut shell and Tamarind) in three levels. Experiments were planned using design of experiments (DOE). On the basis of plans, experiments were conducted to understand the behavior of sand mould properties such as compression strength, shear strength, permeability number with various additives. From the experimental results it could be concluded that the factors have significant effect on the sand properties as P-value found to be less than 0.05 for all the cases studied. The optimization based on quality loss function was also performed. The study revealed that the quality loss associated with the tamarind powder was lesser compared to other additives selected for the study. The optimization based on quality loss function and the parametric analysis using ANOVA suggested that the tamarind powder of 8 gm per Kg of molding sand and moisture content of 7% yield better properties to obtain sound castings.

  2. Additive manufacturing and mechanical characterization of graded porosity scaffolds designed based on triply periodic minimal surface architectures.

    PubMed

    Afshar, M; Anaraki, A Pourkamali; Montazerian, H; Kadkhodapour, J

    2016-09-01

    Since the advent of additive manufacturing techniques, triply periodic minimal surfaces have emerged as a novel tool for designing porous scaffolds. Whereas scaffolds are expected to provide multifunctional performance, spatially changing pore patterns have been a promising approach to integrate mechanical characteristics of different architectures into a unique scaffold. Smooth morphological variations are also frequently seen in nature particularly in bone and cartilage structures and can be inspiring for designing of artificial tissues. In this study, we carried out experimental and numerical procedures to uncover the mechanical properties and deformation mechanisms of linearly graded porosity scaffolds for two different mathematically defined pore structures. Among TPMS-based scaffolds, P and D surfaces were subjected to gradient modeling to explore the mechanical responses for stretching and bending dominated deformations, respectively. Moreover, the results were compared to their corresponding uniform porosity structures. Mechanical properties were found to be by far greater for the stretching dominated structure (P-Surface). For bending dominated architecture (D-Surface), although there was no global fracture for uniform structures, graded structure showed a brittle fracture at 0.08 strain. A layer by layer deformation mechanism for stretching dominated structure was observed. For bending dominated scaffolds, deformation was accompanied by development of 45° shearing bands. Finite element simulations were also performed and the results showed a good agreement with the experimental observations.

  3. Additive manufacturing and mechanical characterization of graded porosity scaffolds designed based on triply periodic minimal surface architectures.

    PubMed

    Afshar, M; Anaraki, A Pourkamali; Montazerian, H; Kadkhodapour, J

    2016-09-01

    Since the advent of additive manufacturing techniques, triply periodic minimal surfaces have emerged as a novel tool for designing porous scaffolds. Whereas scaffolds are expected to provide multifunctional performance, spatially changing pore patterns have been a promising approach to integrate mechanical characteristics of different architectures into a unique scaffold. Smooth morphological variations are also frequently seen in nature particularly in bone and cartilage structures and can be inspiring for designing of artificial tissues. In this study, we carried out experimental and numerical procedures to uncover the mechanical properties and deformation mechanisms of linearly graded porosity scaffolds for two different mathematically defined pore structures. Among TPMS-based scaffolds, P and D surfaces were subjected to gradient modeling to explore the mechanical responses for stretching and bending dominated deformations, respectively. Moreover, the results were compared to their corresponding uniform porosity structures. Mechanical properties were found to be by far greater for the stretching dominated structure (P-Surface). For bending dominated architecture (D-Surface), although there was no global fracture for uniform structures, graded structure showed a brittle fracture at 0.08 strain. A layer by layer deformation mechanism for stretching dominated structure was observed. For bending dominated scaffolds, deformation was accompanied by development of 45° shearing bands. Finite element simulations were also performed and the results showed a good agreement with the experimental observations. PMID:27281165

  4. Estimation of a partially linear additive model for data from an outcome-dependent sampling design with a continuous outcome.

    PubMed

    Tan, Ziwen; Qin, Guoyou; Zhou, Haibo

    2016-10-01

    Outcome-dependent sampling (ODS) designs have been well recognized as a cost-effective way to enhance study efficiency in both statistical literature and biomedical and epidemiologic studies. A partially linear additive model (PLAM) is widely applied in real problems because it allows for a flexible specification of the dependence of the response on some covariates in a linear fashion and other covariates in a nonlinear non-parametric fashion. Motivated by an epidemiological study investigating the effect of prenatal polychlorinated biphenyls exposure on children's intelligence quotient (IQ) at age 7 years, we propose a PLAM in this article to investigate a more flexible non-parametric inference on the relationships among the response and covariates under the ODS scheme. We propose the estimation method and establish the asymptotic properties of the proposed estimator. Simulation studies are conducted to show the improved efficiency of the proposed ODS estimator for PLAM compared with that from a traditional simple random sampling design with the same sample size. The data of the above-mentioned study is analyzed to illustrate the proposed method.

  5. Estimation of a partially linear additive model for data from an outcome-dependent sampling design with a continuous outcome.

    PubMed

    Tan, Ziwen; Qin, Guoyou; Zhou, Haibo

    2016-10-01

    Outcome-dependent sampling (ODS) designs have been well recognized as a cost-effective way to enhance study efficiency in both statistical literature and biomedical and epidemiologic studies. A partially linear additive model (PLAM) is widely applied in real problems because it allows for a flexible specification of the dependence of the response on some covariates in a linear fashion and other covariates in a nonlinear non-parametric fashion. Motivated by an epidemiological study investigating the effect of prenatal polychlorinated biphenyls exposure on children's intelligence quotient (IQ) at age 7 years, we propose a PLAM in this article to investigate a more flexible non-parametric inference on the relationships among the response and covariates under the ODS scheme. We propose the estimation method and establish the asymptotic properties of the proposed estimator. Simulation studies are conducted to show the improved efficiency of the proposed ODS estimator for PLAM compared with that from a traditional simple random sampling design with the same sample size. The data of the above-mentioned study is analyzed to illustrate the proposed method. PMID:27006375

  6. Integrated Autopilot/Autothrottle Based on a Total Energy Control Concept: Design and Evaluation of Additional Autopilot Modes

    NASA Technical Reports Server (NTRS)

    Bruce, Kevin R.

    1988-01-01

    An integrated autopilot/autothrottle system was designed using a total energy control design philosophy. This design ensures that the system can differentiate between maneuvers requiring a change in thrust to accomplish a net energy change, and those maneuvers which only require elevator control to redistribute energy. The system design, the development of the system, and a summary of simulation results are defined.

  7. Additive effects on the improvement of insecticidal activity: Design, synthesis, and insecticidal activity of novel pymetrozine derivatives.

    PubMed

    Yang, Yan; Liu, Yuxiu; Song, Hongjian; Li, Yongqiang; Wang, Qingmin

    2016-02-01

    A series of new pymetrozine analogues containing both methyl on the imine carbon and phenoxy group at the pyridine ring were designed and synthesized. Their insecticidal activities against bean aphid (Aphis craccivora), mosquito larvae (Culex pipiens pallens), cotton bollworm (Helicoverpa armigera), corn borer (Ostrinia nubilalis) and oriental armyworm (Mythimna separata) were evaluated. The results of bioassays indicated that most of the target compounds showed good insecticidal activity against bean aphid; especially, IIIf (80%) and IIIl (80%) exhibited higher aphicidal activity than pymetrozine (30%) at 5mg/kg, and the two compounds still showed 20% and 30% mortality at 2.5mg/kg, respectively, whereas pymetrozine displayed no activity at the same concentration. These compounds exhibited a completely different structure-activity relationship to that of known pymetrozine derivatives, in which it is thought introducing alkyl group on the imine carbon could be detrimental to the activities. Our new result suggested that the methyl on the imine carbon and phenoxy group at the pyridine ring of phenoxy group may play additive effects on the improvement of aphicidal activity. Besides this, compound IIIs, containing an allyl at the para position of phenoxy group, exhibited excellent insecticidal activity against mosquito larvae, lepidoptera pests cotton bollworm, corn borer and oriental armyworm. PMID:26342545

  8. D-OPTIMAL EXPERIMENTAL DESIGNS TO TEST FOR DEPARTURE FROM ADDITIVITY IN A FIXED-RATIO MIXTURE RAY.

    EPA Science Inventory

    Traditional factorial designs for evaluating interactions among chemicals in a mixture are prohibitive when the number of chemicals is large. However, recent advances in statistically-based experimental design have made it easier to evaluate interactions involving many chemicals...

  9. 75 FR 81716 - Additional Designation Pursuant to Executive Order 13469 of July 25, 2008 “Blocking Property of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-28

    ... ``Blocking Property of Additional Persons Undermining Democratic Processes or Institutions in Zimbabwe... ``Blocking Property of Additional Persons Undermining Democratic Processes or Institutions in Zimbabwe'' (the... issued Executive Order 13469 with respect to Zimbabwe pursuant to, inter alia, the...

  10. 40 CFR 267.1103 - What additional design and operating standards apply if liquids will be in my containment building?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... the migration of hazardous constituents into the barrier (for example, a geomembrane covered by a... containment system, including a secondary barrier designed and constructed to prevent migration of...

  11. 76 FR 33762 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-09

    ... decision to designate a class of employees from Vitro Manufacturing, Canonsburg, Pennsylvania, as an... who worked at Vitro Manufacturing in Canonsburg, Pennsylvania, from January 1, 1958 through...

  12. 76 FR 72928 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-28

    ... decision to designate a class of employees from Vitro Manufacturing in Canonsburg, Pennsylvania, as an... worked at Vitro Manufacturing in Canonsburg, Pennsylvania, from January 1, 1960 through September...

  13. 40 CFR 267.1103 - What additional design and operating standards apply if liquids will be in my containment building?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... the migration of hazardous constituents into the barrier (for example, a geomembrane covered by a... containment system, including a secondary barrier designed and constructed to prevent migration of...

  14. 40 CFR 267.1103 - What additional design and operating standards apply if liquids will be in my containment building?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... the migration of hazardous constituents into the barrier (for example, a geomembrane covered by a... containment system, including a secondary barrier designed and constructed to prevent migration of...

  15. 77 FR 5254 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-02

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institute for Occupational Safety and Health Final Effect of Designation of a...: HHS gives notice concerning the final effect of the HHS decision to designate a class of...

  16. 75 FR 51817 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-23

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institute for Occupational Safety and Health Final Effect of Designation of a...: HHS gives notice concerning the final effect of the HHS decision to designate a class of...

  17. 75 FR 51816 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-23

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institute for Occupational Safety and Health Final Effect of Designation of a...: HHS gives notice concerning the final effect of the HHS decision to designate a class of...

  18. 10 CFR 60.132 - Additional design criteria for surface facilities in the geologic repository operations area.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Technical Criteria Design Criteria for... periodically tested. (d) Waste treatment. Radioactive waste treatment facilities shall be designed to process any radioactive wastes generated at the geologic repository operations area into a form suitable...

  19. 10 CFR 60.132 - Additional design criteria for surface facilities in the geologic repository operations area.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Technical Criteria Design Criteria for... periodically tested. (d) Waste treatment. Radioactive waste treatment facilities shall be designed to process any radioactive wastes generated at the geologic repository operations area into a form suitable...

  20. 10 CFR 60.132 - Additional design criteria for surface facilities in the geologic repository operations area.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Technical Criteria Design Criteria for... periodically tested. (d) Waste treatment. Radioactive waste treatment facilities shall be designed to process any radioactive wastes generated at the geologic repository operations area into a form suitable...

  1. 10 CFR 60.132 - Additional design criteria for surface facilities in the geologic repository operations area.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Technical Criteria Design Criteria for... periodically tested. (d) Waste treatment. Radioactive waste treatment facilities shall be designed to process any radioactive wastes generated at the geologic repository operations area into a form suitable...

  2. Performance of portland limestone cements: Cements designed to be more sustainable that include up to 15% limestone addition

    NASA Astrophysics Data System (ADS)

    Barrett, Timothy J.

    In 2009, ASTM and AASHTO permitted the use of up to 5% interground limestone in ordinary portland cement (OPC) as a part of a change to ASTM C150/AASHTO M85. When this work was initiated a new proposal was being discussed that would enable up to 15% interground limestone cement to be considered in ASTM C595/AASHTO M234. This work served to provide rapid feedback to the state department of transportation and concrete industry for use in discussions regarding these specifications. Since the time this work was initiated, ASTM C595/AASHTO M234 was passed (2012c) and PLCs are now able to be specified, however they are still not widely used. The proposal for increasing the volume of limestone that would be permitted to be interground in cement is designed to enable more sustainable construction, which may significantly reduce the CO2 that is embodied in the built infrastructure while also extending the life of cement quarries. Research regarding the performance of cements with interground limestone has been conducted by the cement industry since these cements became widely used in Europe over three decades ago, however this work focuses on North American Portland Limestone Cements (PLCs) which are specifically designed to achieve similar performance as the OPCs they replace.This thesis presents a two-phase study in which the potential for application of cements containing limestone was assessed. The first phase of this study utilized a fundamental approach to determine whether cement with up to 15% of interground or blended limestone can be used as a direct substitute to ordinary portland cement. The second phase of the study assessed the concern of early age shrinkage and cracking potential when using PLCs, as these cements are typically ground finer than their OPC counterparts. For the first phase of the study, three commercially produced PLCs were obtained and compared to three commercially produced OPCs made from the same clinker. An additional cement was tested

  3. Performance of portland limestone cements: Cements designed to be more sustainable that include up to 15% limestone addition

    NASA Astrophysics Data System (ADS)

    Barrett, Timothy J.

    In 2009, ASTM and AASHTO permitted the use of up to 5% interground limestone in ordinary portland cement (OPC) as a part of a change to ASTM C150/AASHTO M85. When this work was initiated a new proposal was being discussed that would enable up to 15% interground limestone cement to be considered in ASTM C595/AASHTO M234. This work served to provide rapid feedback to the state department of transportation and concrete industry for use in discussions regarding these specifications. Since the time this work was initiated, ASTM C595/AASHTO M234 was passed (2012c) and PLCs are now able to be specified, however they are still not widely used. The proposal for increasing the volume of limestone that would be permitted to be interground in cement is designed to enable more sustainable construction, which may significantly reduce the CO2 that is embodied in the built infrastructure while also extending the life of cement quarries. Research regarding the performance of cements with interground limestone has been conducted by the cement industry since these cements became widely used in Europe over three decades ago, however this work focuses on North American Portland Limestone Cements (PLCs) which are specifically designed to achieve similar performance as the OPCs they replace.This thesis presents a two-phase study in which the potential for application of cements containing limestone was assessed. The first phase of this study utilized a fundamental approach to determine whether cement with up to 15% of interground or blended limestone can be used as a direct substitute to ordinary portland cement. The second phase of the study assessed the concern of early age shrinkage and cracking potential when using PLCs, as these cements are typically ground finer than their OPC counterparts. For the first phase of the study, three commercially produced PLCs were obtained and compared to three commercially produced OPCs made from the same clinker. An additional cement was tested

  4. 76 FR 33762 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-09

    ... decision to designate a class of employees from the Linde Ceramics Plant in Tonawanda, New York, as an... worked at the Linde Ceramics Plant in Tonawanda, New York, from January 1, 1954 through December 31,...

  5. 76 FR 72928 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-28

    ... decision to designate a class of employees from W.R. Grace and Company in Curtis Bay, Maryland, as an... worked at any building or area at the facility owned by W.R. Grace and Company in Curtis Bay,...

  6. D-OPTIMAL EXPERIMENTAL DESIGNS TO TEST FOR DEPARTURE FROM ADDITIVITY IN A FIXED-RATIO RAY MIXTURE.

    EPA Science Inventory

    Risk assessors are becoming increasingly aware of the importance of assessing interactions between chemicals in a mixture. Most traditional designs for evaluating interactions are prohibitive when the number of chemicals in the mixture is large. However, evaluation of interacti...

  7. 75 FR 9645 - Additional Designations of Individuals and Entities Pursuant to Section 804(b) of the Foreign...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-03

    ... Act. The list of additional designees is as follows: Individuals 1. MENDEZ VARGAS, Jose de Jesus (a.k...; a.k.a. MENDEZ VARGAS, Jesus; a.k.a. MENDEZ, Jesus), Tazumbos, Jalisco, Mexico; Calle Dr. Lose...

  8. 77 FR 15759 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-16

    ... Ceramics Plant in Tonawanda, New York, as an addition to the Special Exposure Cohort (SEC) under the Energy... to the SEC: All Atomic Weapons Employees who worked in any area at the Linde Ceramics Plant...

  9. 77 FR 60437 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-03

    ... Clarksville Modification Center Site, Ft. Campbell, in Clarksville, Tennessee, as an addition to the Special.... Campbell, in Clarksville, Tennessee, from August 1, 1949, through December 31, 1967, for a number of...

  10. 75 FR 51816 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-23

    ... from the Mound Plant in Miamisburg, Ohio, as an addition to the Special Exposure Cohort (SEC) under the... contractors and subcontractors who had at least one tritium bioassay sample and worked at the Mound Plant...

  11. 76 FR 47646 - Additional Designation of Person Whose Property and Interests in Property Are Blocked Pursuant to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-05

    ... Persons Contributing to the Conflict in Somalia.'' AGENCY: Office of Foreign Assets Control, Treasury... in Somalia.'' DATES: The designation by the Director of OFAC of the individual identified in this... to the Conflict in Somalia'' (the ``Order''), pursuant to, inter alia, the International...

  12. 76 FR 47647 - Additional Designation of Person Whose Property and Interests in Property Are Blocked Pursuant to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-05

    ... Persons Contributing to the Conflict in Somalia.'' AGENCY: Office of Foreign Assets Control, Treasury... in Somalia.'' DATES: The designation by the Director of OFAC of the individual identified in this... to the Conflict in Somalia'' (the ``Order''), pursuant to, inter alia, the International...

  13. 77 FR 65310 - Additional Air Quality Designations for the 2006 24-Hour Fine Particle National Ambient Air...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-26

    ... the 2006 24-hour Fine Particle (PM 2.5 ) National Ambient Air Quality Standards,'' 74 FR 58688... Federal Regulations DC District of Columbia EO Executive Order EPA Environmental Protection Agency FR... EPA finalized designations for the 2006 24-hour PM 2.5 NAAQS (74 FR 58688, November 13, 2009), the...

  14. 40 CFR 267.1103 - What additional design and operating standards apply if liquids will be in my containment building?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... appropriate means, you must include: (a) A primary barrier designed and constructed of materials to prevent...) Constructed of a granular drainage material with a hydraulic conductivity of 1 × 10− 2 cm/sec or more and a thickness of 12 inches (30.5 cm) or more, or constructed of synthetic or geonet drainage materials with...

  15. 76 FR 6056 - Additional Air Quality Designations for the 2006 24-Hour Fine Particle National Ambient Air...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-03

    ... Protection Agency FR Federal Register NAAQS National Ambient Air Quality Standards NTTAA National Technology... (74 FR 58688), EPA deferred designations for three areas to evaluate further the reason for their high... November 13, 2009 notice (74 FR 58688), we also announced that our review of 2006-2008 monitoring data...

  16. 75 FR 3470 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-21

    ... Cohort AGENCY: National Institute for Occupational Safety and Health (NIOSH), Department of Health and... and Controls Corp. in Attleboro, Massachusetts, as an addition to the Special Exposure Cohort (SEC) under the Energy Employees Occupational Illness Compensation Program Act of 2000. On December 10,...

  17. 75 FR 3469 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-21

    ... Hospital in Oak Ridge, Tennessee, as an addition to the Special Exposure Cohort (SEC) under the Energy... and subcontractors who worked in any location at the Oak Ridge Hospital in Oak Ridge, Tennessee, from May 15, 1950 through December 31, 1959, for a number of work days aggregating at least 250 work...

  18. Asymmetric Homoenolate Additions to Acyl Phosphonates through Rational Design of a Tailored N-Heterocyclic Carbene Catalyst

    PubMed Central

    Jang, Ki Po; Hutson, Gerri E.; Johnston, Ryne C.; McCusker, Elizabeth O.; Cheong, Paul H.-Y.; Scheidt, Karl A.

    2014-01-01

    A highly selective NHC-catalyzed synthesis of γ-butyrolactones from the fusion of enals and α-ketophosphonates has been developed. Computational modeling of competing transition states was employed to guide a rational design strategy and achieve enhanced levels of enantioselectivity with a new tailored C1-symmetric biaryl saturated imidazolium-derived NHC catalyst. This new annulation is compatible with a wide range of acyl phosphonates and α,β-unsaturated aldehydes. PMID:24299299

  19. Recent Additions in the Modeling Capabilities of an Open-Source Wave Energy Converter Design Tool: Preprint

    SciTech Connect

    Tom, N.; Lawson, M.; Yu, Y. H.

    2015-04-20

    WEC-Sim is a midfidelity numerical tool for modeling wave energy conversion devices. The code uses the MATLAB SimMechanics package to solve multibody dynamics and models wave interactions using hydrodynamic coefficients derived from frequency-domain boundary-element methods. This paper presents the new modeling features introduced in the latest release of WEC-Sim. The first feature discussed conversion of the fluid memory kernel to a state-space form. This enhancement offers a substantial computational benefit after the hydrodynamic body-to-body coefficients are introduced and the number of interactions increases exponentially with each additional body. Additional features include the ability to calculate the wave-excitation forces based on the instantaneous incident wave angle, allowing the device to weathervane, as well as import a user-defined wave elevation time series. A review of the hydrodynamic theory for each feature is provided and the successful implementation is verified using test cases.

  20. Evidence-Based Communication Practices for Children with Visual Impairments and Additional Disabilities: An Examination of Single-Subject Design Studies

    ERIC Educational Resources Information Center

    Parker, Amy T.; Grimmett, Eric S.; Summers, Sharon

    2008-01-01

    This review examines practices for building effective communication strategies for children with visual impairments, including those with additional disabilities, that have been tested by single-subject design methodology. The authors found 30 studies that met the search criteria and grouped intervention strategies to align any evidence of the…

  1. Viscosity modification of high-oleic sunflower oil with polymeric additives for the design of new biolubricant formulations.

    PubMed

    Quinchia, L A; Delgado, M A; Valencia, C; Franco, J M; Gallegos, C

    2009-03-15

    Although most common lubricants contain mineral or synthetic oils as basestocks, new environmental regulations are demanding environmentally friendly lubricants. In this sense, vegetable oils represent promising alternatives to mineral-based lubricants because of their high biodegradability, good lubricity, and low volatility. However, their poor thermooxidative stability and the small range of viscosity represent a clear disadvantage to be used as suitable biolubricants. The main objective of this work was to develop new environmentally friendly lubricant formulations with improved kinematic viscosity values and viscosity thermal susceptibility. With this aim, a high-oleic sunflower oil (HOSO) was blended with polymeric additives, such as ethylene vinyl acetate (EVA) and styrene-butadiene-styrene (SBS) copolymers, at different concentrations (0.5-5% w/w). Dynamic viscosity and density measurements were performed in a rotational rheometer and capillary densimeter, respectively, in a temperature range between 25 and 120 degrees C. An Arrhenius-like equation fits the evolution of viscosity with temperature fairly well. Both EVA and SBS copolymers may be satisfactorily used as additives to increase the viscosity of HOSO, thus improving the low viscosity values of this oil. HOSO viscosity increases with polymer concentration. Specifically, EVA/HOSO blends exhibit higher viscosity values, which are needed for applications such as lubrication of bearings and four-stroke engines. On the other hand, viscositythermal susceptibility of HOSO samples increases with EVA or SBS concentration.

  2. Designating Additions to the Current List of Tropical Diseases in the Federal Food, Drug, and Cosmetic Act. Final order.

    PubMed

    2015-08-20

    The Federal Food, Drug, and Cosmetic Act (the FD&C Act) authorizes the Food and Drug Administration (FDA or Agency) to award priority review vouchers (PRVs) to tropical disease product applicants when the applications meet certain criteria. The FD&C Act lists the diseases that are considered to be tropical diseases for purposes of obtaining PRVs, and also provides for Agency expansion of that list to include other diseases that satisfy the definition of ``tropical diseases'' as set forth in the FD&C Act. FDA has determined that Chagas disease and neurocysticercosis satisfy this definition, and therefore is adding them to the list of designated tropical diseases whose product applications may result in the award of PRVs. Sponsors submitting certain applications for the treatment of Chagas disease and neurocysticercosis may be eligible to receive a PRV if such applications are approved by FDA.

  3. Designating Additions to the Current List of Tropical Diseases in the Federal Food, Drug, and Cosmetic Act. Final order.

    PubMed

    2015-08-20

    The Federal Food, Drug, and Cosmetic Act (the FD&C Act) authorizes the Food and Drug Administration (FDA or Agency) to award priority review vouchers (PRVs) to tropical disease product applicants when the applications meet certain criteria. The FD&C Act lists the diseases that are considered to be tropical diseases for purposes of obtaining PRVs, and also provides for Agency expansion of that list to include other diseases that satisfy the definition of ``tropical diseases'' as set forth in the FD&C Act. FDA has determined that Chagas disease and neurocysticercosis satisfy this definition, and therefore is adding them to the list of designated tropical diseases whose product applications may result in the award of PRVs. Sponsors submitting certain applications for the treatment of Chagas disease and neurocysticercosis may be eligible to receive a PRV if such applications are approved by FDA. PMID:26292373

  4. Design and Application of Wuhan Ionospheric Oblique Backscattering Sounding System with the Addition of an Antenna Array (WIOBSS-AA).

    PubMed

    Cui, Xiao; Chen, Gang; Wang, Jin; Song, Huan; Gong, Wanlin

    2016-01-01

    The Wuhan Ionospheric Oblique Backscattering Sounding System with the addition of an antenna array (WIOBSS-AA) is the newest member of the WIOBSS family. It is a multi-channel radio system using phased-array antenna technology. The transmitting part of this radio system applies an array composed of five log-periodic antennas to form five beams that span an area to the northwest of the radar site. The hardware and the antenna array of the first multi-channel ionosonde in the WIOBSS family are introduced in detail in this paper. An ionospheric detection experiment was carried out in Chongyang, Hubei province, China on 16 March 2015 to examine the performance of WIOBSS-AA. The radio system demonstrated its ability to obtain ionospheric electron density information over a wide area. The observations indicate that during the experiment, the monitored large-area ionospheric F2-layer was calm and electron density increased with decreasing latitude. PMID:27314360

  5. Design of Selective Gas Sensors Using Additive-Loaded In2O3 Hollow Spheres Prepared by Combinatorial Hydrothermal Reactions

    PubMed Central

    Kim, Sun-Jung; Hwang, In-Sung; Kang, Yun Chan; Lee, Jong-Heun

    2011-01-01

    A combinatorial hydrothermal reaction has been used to prepare pure and additive (Sb, Cu, Nb, Pd, and Ni)-loaded In2O3 hollow spheres for gas sensor applications. The operation of Pd- and Cu-loaded In2O3 sensors at 371 °C leads to selective H2S detection. Selective detection of CO and NH3 was achieved by the Ni-In2O3 sensor at sensing temperatures of 371 and 440 °C, respectively. The gas responses of six different sensors to NH3, H2S, H2, CO and CH4 produced unique gas sensing patterns that can be used for the artificial recognition of these gases. PMID:22346661

  6. Design and Application of Wuhan Ionospheric Oblique Backscattering Sounding System with the Addition of an Antenna Array (WIOBSS-AA)

    PubMed Central

    Cui, Xiao; Chen, Gang; Wang, Jin; Song, Huan; Gong, Wanlin

    2016-01-01

    The Wuhan Ionospheric Oblique Backscattering Sounding System with the addition of an antenna array (WIOBSS-AA) is the newest member of the WIOBSS family. It is a multi-channel radio system using phased-array antenna technology. The transmitting part of this radio system applies an array composed of five log-periodic antennas to form five beams that span an area to the northwest of the radar site. The hardware and the antenna array of the first multi-channel ionosonde in the WIOBSS family are introduced in detail in this paper. An ionospheric detection experiment was carried out in Chongyang, Hubei province, China on 16 March 2015 to examine the performance of WIOBSS-AA. The radio system demonstrated its ability to obtain ionospheric electron density information over a wide area. The observations indicate that during the experiment, the monitored large-area ionospheric F2-layer was calm and electron density increased with decreasing latitude. PMID:27314360

  7. Determination of organic additives in mortars by near-IR spectroscopy. A novel approach to designing a sample set with high-variability components.

    PubMed

    Blanco, Marcelo; Peguero, Anna

    2007-02-01

    Industrial mortars consist primarily of a mixture of cement and an aggregate plus a small amount of additives that are used to modify specific properties. Using too high or too low additive rates usually results in the loss of desirable properties in the end product. This entails carefully controlling the amounts of additives added to mortar in order to ensure correct dosing and/or adequate homogeneity in the final mixture. Near-IR (NIR) spectroscopy has proved effective for this purpose as it requires no sample pretreatment and affords expeditious analyses. The purpose of this work was to determine two organic additives (viz. Ad1 and Ad2) in mortars by using partial least squares regression multivariate calibration models constructed from NIR spectroscopic data. The additives are used to expedite setting and increase cohesion between particles in the mortar. In order to ensure that the sample set contained natural variability in the samples, we used a methodology based on experimental design to construct a representative set of samples. This novel design is based on a hexagonal antiprism that encompasses the concentration ranges spanned by the analytes and the variability inherent in each additive. The D-optimality criterion was used to obtain various combinations between Ad1 and Ad2 additive classes. The partial least squares calibration models thus constructed for each additive provided accurate predictions: the intercept and the slope of the plots of predicted values versus reference values for each additive were close to 0 and 1, respectively, and their confidence ranges included the respective value. The ensuing analytical methods were validated by using an external sample set.

  8. Demonstration of the Recent Additions in Modeling Capabilities for the WEC-Sim Wave Energy Converter Design Tool: Preprint

    SciTech Connect

    Tom, N.; Lawson, M.; Yu, Y. H.

    2015-03-01

    WEC-Sim is a mid-fidelity numerical tool for modeling wave energy conversion (WEC) devices. The code uses the MATLAB SimMechanics package to solve the multi-body dynamics and models the wave interactions using hydrodynamic coefficients derived from frequency domain boundary element methods. In this paper, the new modeling features introduced in the latest release of WEC-Sim will be presented. The first feature discussed is the conversion of the fluid memory kernel to a state-space approximation that provides significant gains in computational speed. The benefit of the state-space calculation becomes even greater after the hydrodynamic body-to-body coefficients are introduced as the number of interactions increases exponentially with the number of floating bodies. The final feature discussed is the capability toadd Morison elements to provide additional hydrodynamic damping and inertia. This is generally used as a tuning feature, because performance is highly dependent on the chosen coefficients. In this paper, a review of the hydrodynamic theory for each of the features is provided and successful implementation is verified using test cases.

  9. Tandem Solar Cells Using GaAs Nanowires on Si: Design, Fabrication, and Observation of Voltage Addition.

    PubMed

    Yao, Maoqing; Cong, Sen; Arab, Shermin; Huang, Ningfeng; Povinelli, Michelle L; Cronin, Stephen B; Dapkus, P Daniel; Zhou, Chongwu

    2015-11-11

    Multijunction solar cells provide us a viable approach to achieve efficiencies higher than the Shockley-Queisser limit. Due to their unique optical, electrical, and crystallographic features, semiconductor nanowires are good candidates to achieve monolithic integration of solar cell materials that are not lattice-matched. Here, we report the first realization of nanowire-on-Si tandem cells with the observation of voltage addition of the GaAs nanowire top cell and the Si bottom cell with an open circuit voltage of 0.956 V and an efficiency of 11.4%. Our simulation showed that the current-matching condition plays an important role in the overall efficiency. Furthermore, we characterized GaAs nanowire arrays grown on lattice-mismatched Si substrates and estimated the carrier density using photoluminescence. A low-resistance connecting junction was obtained using n(+)-GaAs/p(+)-Si heterojunction. Finally, we demonstrated tandem solar cells based on top GaAs nanowire array solar cells grown on bottom planar Si solar cells. The reported nanowire-on-Si tandem cell opens up great opportunities for high-efficiency, low-cost multijunction solar cells.

  10. β-Amino acid catalyzed asymmetric Michael additions: design of organocatalysts with catalytic acid/base dyad inspired by serine proteases.

    PubMed

    Yang, Hui; Wong, Ming Wah

    2011-09-16

    A new type of chiral β-amino acid catalyst has been computationally designed, mimicking the enzyme catalysis of serine proteases. Our catalyst approach is based on the bioinspired catalytic acid/base dyad, namely, a carboxyl and imidazole pair. DFT calculations predict that this designed organocatalyst catalyzes Michael additions of aldehydes to nitroalkenes with excellent enantioselectivities and remarkably high anti diastereoselectivities. The unusual stacked geometry of the enamine intermediate, hydrogen bonding network, and the adoption of an exo transition state are the keys to understand the stereoselectivity.

  11. The Development of Mathematical Prediction Model to Predict Resilient Modulus for Natural Soil Stabilized by Pofa-Opc Additive for the Use in Unpaved Road Design

    NASA Astrophysics Data System (ADS)

    Gamil, Y. M. R.; Bakar, I. H.

    2016-07-01

    Resilient Modulus (Mr) is considered one of the most important parameters in the design of road structure. This paper describes the development of the mathematical model to predict resilient modulus of organic soil stabilized by the mix of Palm Oil Fuel Ash - Ordinary Portland Cement (POFA-OPC) soil stabilization additives. It aims to optimize the use of the use of POFA in soil stabilization. The optimization models enable to eliminate the arbitrary selection and its associated disadvantages in determination of the optimum additive proportion. The model was developed based on Scheffe regression theory. The mix proportions of the samples in the experiment were adopted from similar studies reported in the literature Twenty five samples were designed, prepared and then characterized for each mix proportion based on the MR in 28 days curing. The results are used to develop the mathematical prediction model. The model was statistically analyzed and verified for its adequacy and validity using F-test.

  12. Food additives

    PubMed Central

    Spencer, Michael

    1974-01-01

    Food additives are discussed from the food technology point of view. The reasons for their use are summarized: (1) to protect food from chemical and microbiological attack; (2) to even out seasonal supplies; (3) to improve their eating quality; (4) to improve their nutritional value. The various types of food additives are considered, e.g. colours, flavours, emulsifiers, bread and flour additives, preservatives, and nutritional additives. The paper concludes with consideration of those circumstances in which the use of additives is (a) justified and (b) unjustified. PMID:4467857

  13. Fuel characteristics pertinent to the design of aircraft fuel systems, Supplement I : additional information on MIL-F-7914(AER) grade JP-5 fuel and several fuel oils

    NASA Technical Reports Server (NTRS)

    Barnett, Henry C; Hibbard, Robert R

    1953-01-01

    Since the release of the first NACA publication on fuel characteristics pertinent to the design of aircraft fuel systems (NACA-RM-E53A21), additional information has become available on MIL-F7914(AER) grade JP-5 fuel and several of the current grades of fuel oils. In order to make this information available to fuel-system designers as quickly as possible, the present report has been prepared as a supplement to NACA-RM-E53A21. Although JP-5 fuel is of greater interest in current fuel-system problems than the fuel oils, the available data are not as extensive. It is believed, however, that the limited data on JP-5 are sufficient to indicate the variations in stocks that the designer must consider under a given fuel specification. The methods used in the preparation and extrapolation of data presented in the tables and figures of this supplement are the same as those used in NACA-RM-E53A21.

  14. Effectiveness: N(sub TU) relationships for the design and performance evaluation of additional shell-and-tube heat exchanger geometries

    NASA Astrophysics Data System (ADS)

    1988-11-01

    This Data Item 88021, an addition to the Sub-series on Heat Transfer, complements ESDU 86018 by extending the range of configurations covered there and in particular considering the effect of using small numbers of baffles for E- and J-shells and the use of J-shells in series. It also explores the limitations of the assumptions associated with the effectiveness - N(sub TU) method and shows where those assumptions break down. The curves presented for each exchanger geometry show the locus of designs for which a temperature cross may occur and the locus of 95 percent heat transfer effectiveness which indicates the region of uneconomic design. The method assumes a linear temperature/enthalpy relationship (constant specific heat capacity) for both streams. It applies to boiling or condensing flow of a single component with no temperature change, or boiling and condensing flow of a mixture that is always two-phase. It excludes conditions in which transition from single- to two-phase flow occurs. However, by use of average property values, it is possible to extend the method to apply to cases where there is some variation of physical and thermodynamic properties with temperature.

  15. Phosphazene additives

    DOEpatents

    Harrup, Mason K; Rollins, Harry W

    2013-11-26

    An additive comprising a phosphazene compound that has at least two reactive functional groups and at least one capping functional group bonded to phosphorus atoms of the phosphazene compound. One of the at least two reactive functional groups is configured to react with cellulose and the other of the at least two reactive functional groups is configured to react with a resin, such as an amine resin of a polycarboxylic acid resin. The at least one capping functional group is selected from the group consisting of a short chain ether group, an alkoxy group, or an aryloxy group. Also disclosed are an additive-resin admixture, a method of treating a wood product, and a wood product.

  16. Potlining Additives

    SciTech Connect

    Rudolf Keller

    2004-08-10

    In this project, a concept to improve the performance of aluminum production cells by introducing potlining additives was examined and tested. Boron oxide was added to cathode blocks, and titanium was dissolved in the metal pool; this resulted in the formation of titanium diboride and caused the molten aluminum to wet the carbonaceous cathode surface. Such wetting reportedly leads to operational improvements and extended cell life. In addition, boron oxide suppresses cyanide formation. This final report presents and discusses the results of this project. Substantial economic benefits for the practical implementation of the technology are projected, especially for modern cells with graphitized blocks. For example, with an energy savings of about 5% and an increase in pot life from 1500 to 2500 days, a cost savings of $ 0.023 per pound of aluminum produced is projected for a 200 kA pot.

  17. Total System Performance Assessment-License Application Design Selection (LADS) Phase 1 Analysis of Surface Modification Consisting of Addition of Alluvium (Feature 23a)

    SciTech Connect

    N. Erb

    1999-06-11

    The objective of this report is to document the analysis that was conducted to evaluate the effect of a potential change to the TSPA-VA base case design that could improve long-term repository performance. The design feature evaluated in this report is a modification of the topographic surface of Yucca Mountain. The modification consists of covering the land surface immediately above the repository foot-print with a thick layer of unconsolidated material utilizing rip-rap and plants to mitigate erosion. This surface modification is designated as Feature 23a or simply abbreviated as F23a. The fundamental aim of F23a is to reduce the net infiltration into the unsaturated zone by enhancing the potential for evapotranspiratiration at the surface; such a change would, in turn, reduce the seepage flux and the rate of radionuclide releases from the repository. Field and modeling studies of water movement in the unsaturated zone have indicated that shallow infiltration at the surface is almost negligible in locations where the bedrock is covered by a sufficiently thick soil layer. In addition to providing storage for meteoric water, a thick soil layer would slow the downward movement of soil moisture to such an extent that evaporation and transpiration could easily transfer most of the soil-water back to the atmosphere. Generic requirements for the effectiveness of this design feature are two-fold. First, the soil layer above the repository foot-print must be thick enough to provide sufficient storage of meteoric water (from episodic precipitation events) and accommodate plant roots. Second, the added soil layer must be engineered so as to mitigate thinning by erosional processes and have sufficient thickness to accommodate the roots of common desert plants. Under these two conditions, it is reasonable to expect that modification would be effective for a significant time period and the net infiltration and deep percolation flux would be reduced by orders of magnitude lower

  18. Design of Phosphonium-Type Zwitterion as an Additive to Improve Saturated Water Content of Phase-Separated Ionic Liquid from Aqueous Phase toward Reversible Extraction of Proteins

    PubMed Central

    Ito, Yoritsugu; Kohno, Yuki; Nakamura, Nobuhumi; Ohno, Hiroyuki

    2013-01-01

    We designed phosphonium-type zwitterion (ZI) to control the saturated water content of separated ionic liquid (IL) phase in the hydrophobic IL/water biphasic systems. The saturated water content of separated IL phase, 1-butyl-3-methyimidazolium bis(trifluoromethanesulfonyl)imide, was considerably improved from 0.4 wt% to 62.8 wt% by adding N,N,N-tripentyl-4-sulfonyl-1-butanephosphonium-type ZI (P555C4S). In addition, the maximum water content decreased from 62.8 wt% to 34.1 wt% by increasing KH2PO4/K2HPO4 salt content in upper aqueous phosphate buffer phase. Horse heart cytochrome c (cyt.c) was dissolved selectively in IL phase by improving the water content of IL phase, and spectroscopic analysis revealed that the dissolved cyt.c retained its higher ordered structure. Furthermore, cyt. c dissolved in IL phase was re-extracted again from IL phase to aqueous phase by increasing the concentration of inorganic salts of the buffer solution. PMID:24013379

  19. Solving the Big Data (BD) Problem in Advanced Manufacturing (Subcategory for work done at Georgia Tech. Study Process and Design Factors for Additive Manufacturing Improvement)

    SciTech Connect

    Clark, Brett W.; Diaz, Kimberly A.; Ochiobi, Chinaza Darlene; Paynabar, Kamran

    2015-09-01

    3D printing originally known as additive manufacturing is a process of making 3 dimensional solid objects from a CAD file. This ground breaking technology is widely used for industrial and biomedical purposes such as building objects, tools, body parts and cosmetics. An important benefit of 3D printing is the cost reduction and manufacturing flexibility; complex parts are built at the fraction of the price. However, layer by layer printing of complex shapes adds error due to the surface roughness. Any such error results in poor quality products with inaccurate dimensions. The main purpose of this research is to measure the amount of printing errors for parts with different geometric shapes and to analyze them for finding optimal printing settings to minimize the error. We use a Design of Experiments framework, and focus on studying parts with cone and ellipsoid shapes. We found that the orientation and the shape of geometric shapes have significant effect on the printing error. From our analysis, we also determined the optimal orientation that gives the least printing error.

  20. Study Design and Percent Recoveries of Anthropogenic Organic Compounds With and Without the Addition of Ascorbic Acid to Preserve Water Samples Containing Free Chlorine, 2004-06

    USGS Publications Warehouse

    Valder, Joshua F.; Delzer, Gregory C.; Price, Curtis V.; Sandstrom, Mark W.

    2008-01-01

    The National Water-Quality Assessment (NAWQA) Program of the U.S. Geological Survey (USGS) began implementing Source Water-Quality Assessments (SWQAs) in 2002 that focus on characterizing the quality of source water and finished water of aquifers and major rivers used by some of the larger community water systems in the United States. As used for SWQA studies, source water is the raw (ambient) water collected at the supply well prior to water treatment (for ground water) or the raw (ambient) water collected from the river near the intake (for surface water). Finished water is the water that is treated, which typically involves, in part, the addition of chlorine or other disinfection chemicals to remove pathogens, and is ready to be delivered to consumers. Finished water is collected before the water enters the distribution system. This report describes the study design and percent recoveries of anthropogenic organic compounds (AOCs) with and without the addition of ascorbic acid to preserve water samples containing free chlorine. The percent recoveries were determined by using analytical results from a laboratory study conducted in 2004 by the USGS's National Water Quality Laboratory (NWQL) and from data collected during 2004-06 for a field study currently (2008) being conducted by the USGS's NAWQA Program. The laboratory study was designed to determine if preserving samples with ascorbic acid (quenching samples) adversely affects analytical performance under controlled conditions. During the laboratory study, eight samples of reagent water were spiked for each of five analytical schedules evaluated. Percent recoveries from these samples were then compared in two ways: (1) four quenched reagent spiked samples analyzed on day 0 were compared with four quenched reagent spiked samples analyzed on day 7 or 14, and (2) the combined eight quenched reagent spiked samples analyzed on day 0, 7, or 14 were compared with eight laboratory reagent spikes (LRSs). Percent

  1. An experimental substantiation of the design functions imposed on the additional system for passively flooding the core of a VVER reactor

    NASA Astrophysics Data System (ADS)

    Morozov, A. V.; Remizov, O. V.

    2012-05-01

    Results obtained from a research work on experimentally substantiating the serviceability of the additional system for passively flooding the core of a VVER reactor from the second-stage hydro accumulators are presented.

  2. Design, synthesis, and biological evaluation of simplified analogues of (+)-discodermolide. Additional insights on the importance of the diene, the C7 hydroxyl, and the lactone.

    PubMed

    Smith, Amos B; Xian, Ming

    2005-11-10

    [structure: see text] The design, synthesis, and biological evaluation of seven totally synthetic analogues of the antitumor agent (+)-discodermolide are reported. Saturation of the terminal diene system, alteration of the substituents on the lactone, and alkylation of the C7-hydroxyl group reveal significant structure-activity relationships.

  3. Evidence-Based Design for Project-Based Learning: A Case Study for a 50,000 SF Addition Dedicated to the New Tech Curriculum

    ERIC Educational Resources Information Center

    Moretti, Richard D.; Conte, Philip R.

    2012-01-01

    The Seaford School District, Seaford, Delaware, determined that a component of their "reinvention" of Seaford High School would be the creation of a New Tech Academy, affiliated with the New Tech Network and housed in an addition to that building. The New Tech Network, headquartered in Napa, California, is a rapidly growing association of New Tech…

  4. A Quasi-Experimental Study of Two Selected Units of the Industrial Arts Curriculum Project Materials to Determine the Measurable Additive Effects of a Unit on Design in Manfacturing Technology upon a Similar Unit on Design in Construction Technology.

    ERIC Educational Resources Information Center

    Kuwik, Paul David

    The purpose of the study was to determine whether exposing junior high school students to a unit on design in construction technology and to a unit on design in manufacturing technology significantly affects their achievement on a test measuring "Technological Principles of Design" when compared to a group of junior high school students exposed…

  5. Evaluating the Combined Toxicity of Cu and ZnO Nanoparticles: Utility of the Concept of Additivity and a Nested Experimental Design.

    PubMed

    Liu, Yang; Baas, Jan; Peijnenburg, Willie J G M; Vijver, Martina G

    2016-05-17

    Little is understood regarding the effects of mixtures of different metal-based nanoparticles (NPs). Using concentration-addition (CA) and independent-action (IA) models, we evaluated the combined toxicity of Cu and ZnO NPs based on five nested combinations, i.e., Cu(NO3)2-CuNPs, Zn(NO3)2-ZnONPs, Cu(NO3)2-ZnONPs, Zn(NO3)2-CuNPs, and CuNPs-ZnONPs on root elongation of Lactuca sativa L. The CA and IA models performed equally well in estimating the toxicity of mixtures of Cu(NO3)2-CuNPs, Zn(NO3)2-ZnONPs, and Zn(NO3)2-CuNPs, whereas the IA model was significantly better for fitting the data of Cu(NO3)2-ZnONPs and CuNPs-ZnONPs mixtures. Dissolved Cu proved to be the most toxic metal species to lettuce roots in the tests, followed by Cu NPs, dissolved Zn, and ZnO NPs, respectively. An antagonistic effect was observed for ZnO NPs on the toxicity of Cu NPs. This antagonistic effect is expected to be the result of interactions between dissolved Cu and dissolved Zn, particulate Zn and dissolved Zn, particulate Cu and dissolved Zn, and between particulate Zn and dissolved Cu. In general terms, assuming additivity gives a first indication of the combined toxicity with soluble and insoluble metal particles, both being important in driving the toxicity of metal-based NPs to higher plants. PMID:27070131

  6. Next-generation sequencing studies guide the design of pyrrole-imidazole polyamides with improved binding specificity by the addition of β-alanine.

    PubMed

    Anandhakumar, Chandran; Li, Yue; Kizaki, Seiichiro; Pandian, Ganesh N; Hashiya, Kaori; Bando, Toshikazu; Sugiyama, Hiroshi

    2014-12-15

    The identification of binding sites for small molecules in genomic DNA is important in various applications. Previously, we demonstrated rapid transcriptional activation by our small molecule SAHA-PIP. However, it was not clear whether the strong biological effects exerted by SAHA-PIP were attributable to its binding specificity. Here, we used high-throughput sequencing (Bind-n-seq) to determine the binding specificity of SAHA-PIPs. Sequence specificity bias was determined for SAHA-PIPs (3 and 4), and this showed enhanced 6 bp sequence-specific binding compared with hairpin PIPs (1 and 2). This finding allowed us to investigate the role of the β-alanine that links SAHA to PIP, and led in turn to the design of ββ-PIPs (5 and 6), which showed enhanced binding specificity. Overall, we demonstrated the importance of β-moieties for the binding specificity of PIPs and the use of cost-effective high-throughput screening of these small molecules for binding to the DNA minor groove.

  7. Design

    ERIC Educational Resources Information Center

    Buchanan, Richard; Cross, Nigel; Durling, David; Nelson, Harold; Owen, Charles; Valtonen, Anna; Boling, Elizabeth; Gibbons, Andrew; Visscher-Voerman, Irene

    2013-01-01

    Scholars representing the field of design were asked to identify what they considered to be the most exciting and imaginative work currently being done in their field, as well as how that work might change our understanding. The scholars included Richard Buchanan, Nigel Cross, David Durling, Harold Nelson, Charles Owen, and Anna Valtonen. Scholars…

  8. Perspectives on Additive Manufacturing

    NASA Astrophysics Data System (ADS)

    Bourell, David L.

    2016-07-01

    Additive manufacturing (AM) has skyrocketed in visibility commercially and in the public sector. This article describes the development of this field from early layered manufacturing approaches of photosculpture, topography, and material deposition. Certain precursors to modern AM processes are also briefly described. The growth of the field over the last 30 years is presented. Included is the standard delineation of AM technologies into seven broad categories. The economics of AM part generation is considered, and the impacts of the economics on application sectors are described. On the basis of current trends, the future outlook will include a convergence of AM fabricators, mass-produced AM fabricators, enabling of topology optimization designs, and specialization in the AM legal arena. Long-term developments with huge impact are organ printing and volume-based printing.

  9. Sarks as additional fermions

    NASA Astrophysics Data System (ADS)

    Agrawal, Jyoti; Frampton, Paul H.; Jack Ng, Y.; Nishino, Hitoshi; Yasuda, Osamu

    1991-03-01

    An extension of the standard model is proposed. The gauge group is SU(2) X ⊗ SU(3) C ⊗ SU(2) S ⊗ U(1) Q, where all gauge symmetries are unbroken. The colour and electric charge are combined with SU(2) S which becomes strongly coupled at approximately 500 GeV and binds preons to form fermionic and vector bound states. The usual quarks and leptons are singlets under SU(2) X but additional fermions, called sarks. transform under it and the electroweak group. The present model explains why no more than three light quark-lepton families can exist. Neutral sark baryons, called narks, are candidates for the cosmological dark matter having the characteristics designed for WIMPS. Further phenomenological implications of sarks are analyzed i including electron-positron annihilation. Z 0 decay, flavor-changing neutral currents. baryon-number non-conservation, sarkonium and the neutron electric dipole moment.

  10. Additive manufacturing of optical components

    NASA Astrophysics Data System (ADS)

    Heinrich, Andreas; Rank, Manuel; Maillard, Philippe; Suckow, Anne; Bauckhage, Yannick; Rößler, Patrick; Lang, Johannes; Shariff, Fatin; Pekrul, Sven

    2016-08-01

    The development of additive manufacturing methods has enlarged rapidly in recent years. Thereby, the work mainly focuses on the realization of mechanical components, but the additive manufacturing technology offers a high potential in the field of optics as well. Owing to new design possibilities, completely new solutions are possible. This article briefly reviews and compares the most important additive manufacturing methods for polymer optics. Additionally, it points out the characteristics of additive manufactured polymer optics. Thereby, surface quality is of crucial importance. In order to improve it, appropriate post-processing steps are necessary (e.g. robot polishing or coating), which will be discussed. An essential part of this paper deals with various additive manufactured optical components and their use, especially in optical systems for shape metrology (e.g. borehole sensor, tilt sensor, freeform surface sensor, fisheye lens). The examples should demonstrate the potentials and limitations of optical components produced by additive manufacturing.

  11. 78 FR 28289 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-14

    ...; citizen Mexico (individual) . 7. SALAZAR RAMIREZ, Jesus Alfredo (a.k.a. ``INDIO''; a.k.a. ``MUNE''); DOB 24 Mar 1974; POB Chihuahua, Mexico; citizen Mexico (individual) . 8. SOSA CANISALES, Felipe de...

  12. 75 FR 10557 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-08

    ... Ceja, Antioquia, Colombia; Cedula No. 41420126 (Colombia) (individual) . 13. BERNAL LONDONO, Jesus... (Colombia) . 29. ECHEVERRY CADAVID, Nebio De Jesus (a.k.a. ECHEVERRI, Nevio; a.k.a. ECHEVERRY, Nevio), c/o..., Jesus Antonio, Calle 47 Bis No. 28-55, Villavicencio, Colombia; c/o INVERSIONES AGROINDUSTRIALES...

  13. 78 FR 36635 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-18

    ....R.P. RICH720121MJCBRL08 (Mexico) (individual) . 12. SANCHEZ BARBA, Jose de Jesus, Av. Vallarta No.... SANCHEZ GARZA, Jose de Jesus, Av. Vallarta No. 3060, Colonia Vallarta San Jorge, Guadalajara,...

  14. 77 FR 48609 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-14

    ...'S SUPERMARKET COMPANY LTD. 2. ZABANEH, John (a.k.a. ZABANEH, John Angel), Big Creek, Belize; 3....), 7292 George Price Blvd., P.O. Box 657, Belmopan, Belize; 10/12 Halfmoon Avenue, Belmopan City, Belize...), 671 Ecumenical Drive, P.O. Box 64, Dangriga Town, Belize . 3. D'S SUPERMARKET COMPANY LTD. (a.k.a....

  15. 77 FR 23807 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-20

    ... Juarez, Valentin Gomez Farias 120A, Puerto Vallarta, Jalisco, Mexico; Puerta de Hierro 5594, Colonia...--B, Colonia Reg. 92, Quintana Roo, Benito Juarez 77516, Mexico; Avenida Vallarta No. 6503, Piso 15..., Col. Napoles, Benito Juarez, Mexico City, Distrito Federal 03810, Mexico; Wisconsin No. 68,...

  16. 76 FR 58562 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-21

    ..., Colonia Villa de Cortes, Delegacion Benito Juarez, Mexico City, Distrito Federal, Mexico; Folio Mercantil No. 325909 (Mexico); (ENTITY) . 2. TATES DESARROLLO, S.A. DE C.V., Avenida San Jeronimo No. 630 Trc. 16, Colonia Barrio San Jeronimo Lidice, Delegacion La Magdalena Contreras, Mexico City,...

  17. 77 FR 63418 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-16

    ..., Benito Juarez, Quintana Roo C.P. 77533, Mexico; Calle Morelos No. 2223, Colonia Arcos Vallarta... 1, Colonia Residencia Sol del Mayab, Benito Juarez, Quintana Roo C.P. 77533, Mexico; Calle Morelos....P. 45238, Mexico; Cancun, Quintana Roo, Mexico; R.F.C. SRC-080222-274 (Mexico) . 2....

  18. 78 FR 47828 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-06

    ...: 1. NUNEZ BEDOYA, Jose Antonio, Calle Lic. Benito Juarez No. 396, Interior No. 5, Colonia Centro, Culiacan, Sinaloa 80000, Mexico; DOB 21 Dec 1941; POB Sinaloa, Mexico; nationality Mexico; citizen Mexico; R.F.C. NUBA411221867 (Mexico); C.U.R.P. NUBA411221HSLXDN05 (Mexico) (individual) . 2. GARCIA...

  19. 75 FR 64781 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-20

    ..., Delegacion Benito Juarez, Mexico City, Mexico; Folio Mercantil No. 325909 (Mexico); (ENTITY) 2. TATES DESARROLLO, S.A. DE C.V., Mexico City, Mexico; Folio Mercantil No. 345497 (Mexico); (ENTITY) 3. FLORBEL OPERADORA DE RESTAURANTES, S.A. DE C.V., Mexico City, Mexico; Folio Mercantil No. 310801 (Mexico);...

  20. 77 FR 61051 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-05

    ..., Delegacion Benito Juarez, Distrito Federal Codigo Postal 03300, Mexico; Circuito de las Flores Norte 2252... Juarez, Distrito Federal Codigo Postal 03100, Mexico; Castillo de Kent 38, Manzana 26 Lote 37, Condado de.... 366, Planta Alta, Colonia Narvarte, Delegacion Benito Juarez, Distrito Federal Codigo Postal...

  1. 77 FR 29755 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-18

    ... of the Central Intelligence Agency, the Director of the Federal Bureau of Investigation, the... AGENCY: Office of Foreign Assets Control, Treasury. ACTION: Notice. SUMMARY: The U.S. Department of...

  2. 75 FR 65554 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-25

    ... Secretary of the Treasury may in consultation with the Attorney General, the Director of the Central Intelligence Agency, the Director of the Federal Bureau of Investigation, the Administrator of the Drug... AGENCY: Office of Foreign Assets Control, Treasury. ACTION: Notice. SUMMARY: The Treasury...

  3. 76 FR 23644 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-27

    ... Secretary of the Treasury in consultation with the Attorney General, the Director of the Central Intelligence Agency, the Director of the Federal Bureau of Investigation, the Administrator of the Drug... AGENCY: Office of Foreign Assets Control, Treasury. ACTION: Notice. SUMMARY: The Treasury...

  4. 77 FR 22846 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-17

    ... of the Central Intelligence Agency, the Director of the Federal Bureau of Investigation, the... AGENCY: Office of Foreign Assets Control, Treasury. ACTION: Notice. SUMMARY: The U.S. Department of...

  5. 75 FR 20425 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-19

    ... Secretary of the Treasury consults with the Attorney General, the Director of the Central Intelligence Agency, the Director of the Federal Bureau of Investigation, the Administrator of the Drug Enforcement... AGENCY: Office of Foreign Assets Control, Treasury. ACTION: Notice. SUMMARY: The Department of...

  6. 77 FR 28670 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-15

    ... of the Central Intelligence Agency, the Director of the Federal Bureau of Investigation, the... AGENCY: Office of Foreign Assets Control, Treasury. ACTION: Notice. SUMMARY: The U.S. Department of...

  7. 76 FR 10668 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-25

    ..., the Director of the Central Intelligence Agency, the Director of the Federal Bureau of Investigation... AGENCY: Office of Foreign Assets Control, Treasury. ACTION: Notice. SUMMARY: The Treasury...

  8. 78 FR 3083 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-15

    ... of the Central Intelligence Agency, the Director of the Federal Bureau of Investigation, the... AGENCY: Office of Foreign Assets Control, Treasury. ACTION: Notice. SUMMARY: The U.S. Department of...

  9. 76 FR 56875 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-14

    ... the Central Intelligence Agency, the Director of the Federal Bureau of Investigation, the... AGENCY: Office of Foreign Assets Control, Treasury. ACTION: Notice. SUMMARY: The Treasury Department's..., Venezuelan Intelligence Service-SEBIN (individual) Dated: September 8, 2011. Adam J. Szubin, Director,...

  10. 77 FR 38140 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-26

    ... General, the Director of the Central Intelligence Agency, the Director of the Federal Bureau of... AGENCY: Office of Foreign Assets Control, Treasury. ACTION: Notice. SUMMARY: The U.S. Department of...

  11. 78 FR 59766 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-27

    ... General, the Director of the Central Intelligence Agency, the Director of the Federal Bureau of... AGENCY: Office of Foreign Assets Control, Treasury. ACTION: Notice. SUMMARY: The U.S. Department of the..., Distrito Central, Francisco Morazan, Honduras; Barrio Los Laureles, Carretera Panamericana Norte contiguo...

  12. 76 FR 25407 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-04

    ... Secretary of the Treasury, in consultation with the Attorney General, the Director of the Central Intelligence Agency, the Director of the Federal Bureau of Investigation, the Administrator of the Drug... AGENCY: Office of Foreign Assets Control, Treasury. ACTION: Notice. SUMMARY: The Treasury...

  13. 76 FR 25406 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-04

    ... Secretary of the Treasury consults with the Attorney General, the Director of the Central Intelligence Agency, the Director of the Federal Bureau of Investigation, the Administrator of the Drug Enforcement... AGENCY: Office of Foreign Assets Control, Treasury. ACTION: Notice. SUMMARY: The Treasury...

  14. 77 FR 56271 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-12

    ... of the Central Intelligence Agency, the Director of the Federal Bureau of Investigation, the... AGENCY: Office of Foreign Assets Control, Treasury. ACTION: Notice. SUMMARY: The U.S. Department of...

  15. 78 FR 53007 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-27

    ... of the Central Intelligence Agency, the Director of the Federal Bureau of Investigation, the... AGENCY: Office of Foreign Assets Control, Treasury. ACTION: Notice. SUMMARY: The U.S. Department of...

  16. 76 FR 67792 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-02

    ..., the Director of the Central Intelligence Agency, the Director of the Federal Bureau of Investigation... AGENCY: Office of Foreign Assets Control, Treasury. ACTION: Notice. SUMMARY: The Treasury...

  17. 77 FR 2347 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-17

    ... of the Central Intelligence Agency, the Director of the Federal Bureau of Investigation, the... AGENCY: Office of Foreign Assets Control, Treasury. ACTION: Notice. SUMMARY: The U.S. Department of...

  18. 76 FR 5858 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-02

    ..., the Director of the Central Intelligence Agency, the Director of the Federal Bureau of Investigation... AGENCY: Office of Foreign Assets Control, Treasury. ACTION: Notice. SUMMARY: The Treasury...

  19. 75 FR 65554 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-25

    ... Secretary of the Treasury consults with the Attorney General, the Director of the Central Intelligence Agency, the Director of the Federal Bureau of Investigation, the Administrator of the Drug Enforcement... AGENCY: Office of Foreign Assets Control, Treasury. ACTION: Notice. SUMMARY: The Treasury...

  20. 75 FR 24773 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-05

    ... Secretary of the Treasury consults with the Attorney General, the Director of the Central Intelligence Agency, the Director of the Federal Bureau of Investigation, the Administrator of the Drug Enforcement... AGENCY: Office of Foreign Assets Control, Treasury. ACTION: Notice. SUMMARY: The Treasury...

  1. 78 FR 5562 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-25

    ... General, the Director of the Central Intelligence Agency, the Director of the Federal Bureau of... AGENCY: Office of Foreign Assets Control, Treasury. ACTION: Notice. SUMMARY: The U.S. Department of...

  2. 78 FR 62946 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-22

    ... General, the Director of the Central Intelligence Agency, the Director of the Federal Bureau of... AGENCY: Office of Foreign Assets Control, Treasury. ACTION: Notice. SUMMARY: The U.S. Department of...

  3. 77 FR 69706 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-20

    ... General, the Director of the Central Intelligence Agency, the Director of the Federal Bureau of... AGENCY: Office of Foreign Assets Control, Treasury. ACTION: Notice. SUMMARY: The U.S. Department of...

  4. 77 FR 14859 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-13

    ... Secretary of the Treasury in consultation with the Attorney General, the Director of the Central Intelligence Agency, the Director of the Federal Bureau of Investigation, the Administrator of the Drug... AGENCY: Office of Foreign Assets Control, Treasury. ACTION: Notice. SUMMARY: The Treasury...

  5. 78 FR 29814 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-21

    ... of the Central Intelligence Agency, the Director of the Federal Bureau of Investigation, the... AGENCY: Office of Foreign Assets Control, Treasury. ACTION: Notice. SUMMARY: The U.S. Department of...

  6. 77 FR 4400 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-27

    ... Attorney General, the Director of the Central Intelligence Agency, the Director of the Federal Bureau of... AGENCY: Office of Foreign Assets Control, Treasury. ACTION: Notice. SUMMARY: The U.S. Department of...

  7. 76 FR 5857 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-02

    ..., the Director of the Central Intelligence Agency, the Director of the Federal Bureau of Investigation... AGENCY: Office of Foreign Assets Control, Treasury. ACTION: Notice. SUMMARY: The Treasury Department's... Street, Central District, Beirut, Lebanon (ENTITY) 3. SOLMAR, Atrium Building, Weygand Street,...

  8. 78 FR 13760 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-28

    ... of the Central Intelligence Agency, the Director of the Federal Bureau of Investigation, the... AGENCY: Office of Foreign Assets Control, Treasury. ACTION: Notice. SUMMARY: The U.S. Department of...

  9. 77 FR 74915 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-18

    ... Secretary of the Treasury, in consultation with the Attorney General, the Director of the Central Intelligence Agency, the Director of the Federal Bureau of Investigation, the Administrator of the Drug... AGENCY: Office of Foreign Assets Control, Treasury. ACTION: Notice. SUMMARY: The U.S. Department of...

  10. 78 FR 8701 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-06

    ... General, the Director of the Central Intelligence Agency, the Director of the Federal Bureau of... AGENCY: Office of Foreign Assets Control, Treasury. ACTION: Notice. SUMMARY: The U.S. Department of...

  11. 77 FR 71480 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-30

    ... General, the Director of the Central Intelligence Agency, the Director of the Federal Bureau of... AGENCY: Office of Foreign Assets Control, Treasury. ACTION: Notice. SUMMARY: The U.S. Department of...

  12. 77 FR 36041 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-15

    ... of the Central Intelligence Agency, the Director of the Federal Bureau of Investigation, the... AGENCY: Office of Foreign Assets Control, Treasury. ACTION: Notice. ] SUMMARY: The U.S. Department of the...), Avenida Central 1191-35, Condominio Malaga, Colonia Parques de la Castellana, Zapopan, Jalisco,...

  13. 77 FR 58912 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-24

    ... General, the Director of the Central Intelligence Agency, the Director of the Federal Bureau of... AGENCY: Office of Foreign Assets Control, Treasury. ACTION: Notice. SUMMARY: The U.S. Department of the...) (individual) Linked To: CONSTRUCTORA FR DE VENEZUELA, C.A. Entity: 2. CONSTRUCTORA FR DE VENEZUELA, C.A....

  14. 77 FR 44715 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-30

    ..., S.A. DE C.V., Blvd. Enrique Felix Castro No. 1029, Col. Desarrollo Urbano Tres Rios, Culiacan...., Manuel J. Clouthier No. 1800, Col. Libertad, Culiacan, Sinaloa C.P. 80180, Mexico; R.F.C. GSA-...

  15. 78 FR 53191 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-28

    ... C.V., Blvd. Enrique Felix Castro No. 1029, Col. Desarrollo Urbano Tres Rios, Culiacan, Sinaloa C.P.... Clouthier No. 1800, Col. Libertad, Culiacan, Sinaloa C.P.80180, Mexico; R.F.C. GSA- 100223-M92 (Mexico) . 4.... Enrique Felix Castro No. 1029, Col. Desarrollo Urbano Tres Rios, Culiacan, Sinaloa C.P. 80020, Mexico;...

  16. 76 FR 6843 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-08

    ..., Jalisco, Mexico; Ciudad Victoria, Allende Hwy, Allende, Guanajuato, Mexico; Ocampo 49, Tecalitlan, Jalisco...; Fraccionamiento Santa Isabel, Paseo San Eliseo 1695, Zapopan, Jalisco, Mexico; DOB 11 Aug 1976; alt. DOB 2...

  17. 78 FR 66105 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-04

    .... CALLE QUIROS, Luis Santiago, Madrid, Spain; Lima, Peru; DOB 22 Jul 1965; POB Madrid, Spain; citizen Spain; alt. citizen Peru; D.N.I. 01927713-Z (Spain); alt. D.N.I. 10831176-8 (Peru) (individual) (Linked To: TEXTIMAX SPAIN S.L.; Linked To: CASTIZAL MADRILENA S.L.; Linked To: INMOBILIARIA CASTIZAL...

  18. 77 FR 51616 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-24

    ...: INMOBILIARIA DATEUS; Linked To: WALNUTHILL; Linked To: CABOMARZO; Linked To: GRUPO MPV; Linked To: DELPSA... 135027 . 22. INMOBILIARIA DATEUS, 1era Avenida 7-60, Zona 14, Apartamento 1602 Del Edificio...

  19. 78 FR 66990 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-07

    .... INMOBILIARIA PROMINENTE, S.A. DE C.V., Guadalajara, Jalisco, Mexico; Folio Mercantil No. 12354-1 (Mexico) . 11... ENERGETICOS, S.A. DE C.V.; Linked To: ENERGETICOS VAGO, S.A. DE C.V.; Linked To: INMOBILIARIA PROMINENTE, S.A...: INMOBILIARIA PROMINENTE, S.A. DE C.V.; Linked To: NUEVA TERRA, S. DE R.L. DE C.V.; Linked To: OPERADORA ENGO,...

  20. 75 FR 36474 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-25

    ..., Quito, Pichincha, Ecuador; DOB 16 Nov 1973; POB Santo Domingo, Ecuador; Citizen Ecuador; Cedula No. 1712394947 (Ecuador); Passport 1712394947 (Ecuador); (INDIVIDUAL) . 3. OSTAIZA AMAY, Edison Ariolfo, c/o MULTINACIONAL INTEGRAL PRODUCTIVA JOOAMY EMA, Quito, Pichincha, Ecuador; DOB 19 Jul 1975; Citizen...

  1. 78 FR 70630 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-26

    ... SEGURIDAD PRIVADA, S.A. DE C.V., Mexialtzingo 1964, Col. Americana, Guadalajara, Jalisco 44150, Mexico; RFC... Tlalpan, Mexico, D.F., Mexico; DOB 11 Dec 1961; POB Fresnillo, Zacatecas, Mexico; nationality Mexico; Tax ID No. 06796108238 (Mexico); C.U.R.P. LOHM611211HZSZRG11 (Mexico) (individual) . 2. VILLA...

  2. 75 FR 15772 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-30

    ..., Mexico; Citizen Mexico; Nationality Mexico; (INDIVIDUAL) 4. VELASQUEZ CABALLERO, Ivan (a.k.a. VELAZQUEZ.... VELAZQUEZ CABALLERO, Juan Daniel); Colonia Infonavit, Nuevo Laredo, Tamaulipas, Mexico; Colonia Buena...

  3. 75 FR 27118 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-13

    ...); (INDIVIDUAL) 13. JIMENEZ URREGO, Luz Marina, c/o C.I. STONES AND BYPRODUCTS TRADING S.A., Bogota, Colombia; c...; Cedula No. 79263544 (Colombia); (INDIVIDUAL) 19. MORENO BERNAL, Luz Marina, c/o PROMOTORA HOTELERA...

  4. 77 FR 39573 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-03

    ... Melean, cruce con Calle No. 73, Local No. 22, Sector Santa Rosa, Valencia, Venezuela; Calle 10A No.12-21, Maicao, Colombia; Carrera 70 No. 76-50 BG 3, Barranquilla, Colombia; Calle 10 No 11-63, Maicao, Colombia.... 11-63, Maicao, La Guajira, Colombia; Calle 13 No. 10-34 Centro, Maicao, La Guajira, Colombia; DOB...

  5. 78 FR 9997 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-12

    ... objective of denying their businesses and agents access to the U.S. financial system and the benefits of... Attorney General, the Director of the Central Intelligence Agency, the Director of the Federal Bureau of... & NACIONAL EXCHANGE SERVICES, INC., Pharr, TX; Business Registration Document 801199276 (Texas); Tax ID...

  6. 75 FR 44311 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-28

    ... organizations on a worldwide basis, with the objective of denying their businesses and agents access to the U.S... Secretary of the Treasury consults with the Attorney General, the Director of the Central...

  7. 78 FR 22620 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-16

    .... DE C.V.; a.k.a. SUPERTIENDAS & AUTO PARTES HANDAL), 3 Ave y 14 Calle N.O., Barrio Las Acacias... Las Acacias, Apartado Postal No 1018, San Pedro Sula, Cortes, Honduras . 3. EASY CASH S. DE R.L., San... Copan, Copan, Honduras . 5. JM TROYA, 3 Ave y 14 Calle N.O., Barrio Las Acacias, Apartado Postal No...

  8. 75 FR 34214 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-16

    ..., Colonia Las Americas Britania, CP 58270, Morelia, Michoac n; Calle Ignacio Allende S/N Casi Esquina Con... Centro, M gica, Michoac n, Mexico; Calle Ignacio Allende S/N Casi Esquina Con Lazaro Cardenas...

  9. 77 FR 838 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-06

    ... POLYTON (ASIA) LIMITED; DOB 10 Feb 1966; POB Maicao, La Guajira, Colombia; Cedula No. 84046545 (Colombia... Guajira, Colombia; Cedula No. 17849451 (Colombia) (individual) . 7. FADLALLAH CHEAYTELLI, Jaime, c/o... Maicao, La Guajira, Colombia; Cedula No. 84048039 (Colombia) (individual) . 8. FADLALLATH...

  10. 75 FR 79440 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-20

    ... Alberto, c/o MELRUX RICA S PIZZA, Bogota, Colombia; Calle 24C No. 75-59, Bogota, Colombia; Calle 119A No... RICAS PIZZA, Bogota, Colombia; DOB 26 Mar 1948; Cedula No. 41386662 (Colombia) (individual) 10. MOLANO...; NIT 890935433-8 (Colombia) 5. AMG RICAS PIZZA (a.k.a. FUSION PIZZA & PARRILLA; a.k.a. RICA'S...

  11. 76 FR 59483 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-26

    ... Federal, Mexico; c/o INVERSIONES CIFUENTES Y CIA. S. EN C., Medellin, Colombia; c/o ROBLE DE MINAS S.A...-70 Of. 1205, Medellin, Colombia; NIT 811035904-6 (Colombia) 9. ROBLE DE MINAS S.A., Calle 18B Sur No...., Lavalleja, Uruguay; c/o INVERSIONES CIFUENTES Y CIA. S. EN C., Medellin, Colombia; c/o ROBLE DE MINAS...

  12. 76 FR 11561 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-02

    ... COMPANIA S.C.S., Medellin, Colombia; c/o ECOVIVERO EL MATORRAL E.U., Medellin, Colombia; c/o ROBLE DE MINAS..., Colombia; c/o ROBLE DE MINAS S.A., Medellin, Colombia; c/o UNION DE CONSTRUCTORES CONUSA S.A., Bogota... DE MINAS S.A., Medellin, Colombia; Calle 16C Sur No. 42-70, Medellin, Colombia; DOB 18 Jan 1968;...

  13. 75 FR 64782 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-20

    ... Act. The list of designees is as follows: Entities 1. GENETICA GANADERA RANCHO ALEJANDRA S.P.R. DE R...; (ENTITY) . 2. GENETICA IMPORT-EXPORT S.P.R. DE R.L. DE C.V., Calle Alvarado No. 143, Local 5-J, Zona...- 690830 (Mexico); (INDIVIDUAL) . 14. OLVERA ESTRADA, Rodolfo, c/o GENETICA GANADERA RANCHO ALEJANDRA...

  14. 75 FR 14255 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-24

    .... 71981992 (Colombia); (INDIVIDUAL) 12. TORRES MARTINEZ, Camilo, c/o REPUESTOS EL NATO Y CIA LTDA., Medellin... BANANERO S.A., Apartado, Antioquia, Colombia; c/o REPUESTOS EL NATO Y CIA LTDA., Medellin, Colombia... No. 75C-40, Medellin, Colombia; NIT 9000750838 (Colombia); (ENTITY) 21. REPUESTOS EL NATO Y CIA...

  15. 78 FR 42589 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-16

    ... LIMITADA; Linked To: GUBEREK GRIMBERG E HIJOS Y CIA. S. EN C.; Linked To: CONSTRUCTORA NACIONAL DE PANAMA S... TEJIDOS S.A.; Linked To: COMPANIA REAL DE PANAMA S.A.; Linked To: GUBEREK GRIMBERG E HIJOS Y CIA. S. EN C... 1730043 (Colombia); alt. Matricula Mercantil No 1816081 (Colombia) . 12. GUBEREK GRIMBERG E HIJOS Y CIA....

  16. 77 FR 6191 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-07

    ... S.R.L.; Prundeni, Valcea, Romania; DOB 01 Mar 1946; POB Mardin, Turkey; nationality Turkey; CNP (Personal Numerical Code) 7460301380011 (Romania); Romanian Permanent Resident CAN 0125477 (Romania) issued..., Ilfov 70000, Romania; Romanian C.R. J23/242/2004 (Romania) . 2. GELRO IMPEX S.R.L., Cart. Cring, Bloc...

  17. 78 FR 61000 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-02

    ...: GRUPO COMERCIAL ROOL, S.A. DE C.V.). 4. REYES MAGANA, Felipe, Calle Juan Jose Arreola 535, Col. Lomas... RODRIGUEZ, Luis Fernando; a.k.a. RODRIGUEZ MORFIN, Luis; a.k.a. RODRIGUEZ OLIVERA, Luis Fernando), Plaza.... RODRIGUEZ OLIVERA, Luis (a.k.a. MORFAN RODRIGUEZ, Luis Fernando; a.k.a. RODRIGUEZ MORFIN, Luis;...

  18. Color Addition and Subtraction Apps

    NASA Astrophysics Data System (ADS)

    Ruiz, Frances; Ruiz, Michael J.

    2015-10-01

    Color addition and subtraction apps in HTML5 have been developed for students as an online hands-on experience so that they can more easily master principles introduced through traditional classroom demonstrations. The evolution of the additive RGB color model is traced through the early IBM color adapters so that students can proceed step by step in understanding mathematical representations of RGB color. Finally, color addition and subtraction are presented for the X11 colors from web design to illustrate yet another real-life application of color mixing.

  19. Rationale, design and methods of the Study of Work and Pain (SWAP): a cluster randomised controlled trial testing the addition of a vocational advice service to best current primary care for patients with musculoskeletal pain (ISRCTN 52269669)

    PubMed Central

    2014-01-01

    Background Musculoskeletal pain is a major contributor to short and long term work absence. Patients seek care from their general practitioner (GP) and yet GPs often feel ill-equipped to deal with work issues. Providing a vocational case management service in primary care, to support patients with musculoskeletal problems to remain at or return to work, is one potential solution but requires robust evaluation to test clinical and cost-effectiveness. Methods/Design This protocol describes a cluster randomised controlled trial, with linked qualitative interviews, to investigate the effect of introducing a vocational advice service into general practice, to provide a structured approach to managing work related issues in primary care patients with musculoskeletal pain who are absent from work or struggling to remain in work. General practices (n = 6) will be randomised to offer best current care or best current care plus a vocational advice service. Adults of working age who are absent from or struggling to remain in work due to a musculoskeletal pain problem will be invited to participate and 330 participants will be recruited. Data collection will be through patient completed questionnaires at baseline, 4 and 12 months. The primary outcome is self-reported work absence at 4 months. Incremental cost-utility analysis will be undertaken to calculate the cost per additional QALY gained and incremental net benefits. A linked interview study will explore the experiences of the vocational advice service from the perspectives of GPs, nurse practitioners (NPs), patients and vocational advisors. Discussion This paper presents the rationale, design, and methods of the Study of Work And Pain (SWAP) trial. The results of this trial will provide evidence to inform primary care practice and guide the development of services to provide support for musculoskeletal pain patients with work-related issues. Trial registration Current Controlled Trials ISRCTN52269669. PMID:25012813

  20. [Food additives and healthiness].

    PubMed

    Heinonen, Marina

    2014-01-01

    Additives are used for improving food structure or preventing its spoilage, for example. Many substances used as additives are also naturally present in food. The safety of additives is evaluated according to commonly agreed principles. If high concentrations of an additive cause adverse health effects for humans, a limit of acceptable daily intake (ADI) is set for it. An additive is a risk only when ADI is exceeded. The healthiness of food is measured on the basis of nutrient density and scientifically proven effects.

  1. Design of a Drug-in-Adhesive Transdermal Patch for Risperidone: Effect of Drug-Additive Interactions on the Crystallization Inhibition and In Vitro/In Vivo Correlation Study.

    PubMed

    Weng, Wei; Quan, Peng; Liu, Chao; Zhao, Hanqing; Fang, Liang

    2016-10-01

    The purpose of this work was to develop and design an appropriate drug-in-adhesive patch for transdermal delivery of risperidone (RISP). Various formulation factors were investigated by in vitro permeation study using excised rabbit skin. Increasing the drug concentration in the pressure sensitive adhesive (PSA) was used to enhance the drug permeation. To overcome the high crystallization tendency of the patch, several crystallization inhibitors such as PVP, PEG, and surfactants and fatty acids were evaluated by microscopy study. The mechanism of crystallization inhibition was investigated by differential scanning calorimetry, nuclear magnetic resonance spectrometer, and FT-IR studies. RISP and its active metabolite were determined after topical application of the optimized transdermal patch, and the in vivo pharmacokinetic parameters were compared with the intravenous administration group. The microscopy study indicated that fatty acid greatly inhibited the crystallization of RISP in PSA. The inhibition was attributed to the drug-additive interaction between amino group of RISP and the carboxyl group of fatty acid which was further confirmed by (1)H-NMR and FT-IR studies. The optimal permeation profile was obtained with the patches containing 5% RISP and 5% oleic acid in Duro-Tak(®) 87-2287. The in vivo pharmacokinetic study exhibited a sustained absorption and metabolism profile and well correlated with the in vitro permeation data. PMID:27522527

  2. Polyimide processing additives

    NASA Technical Reports Server (NTRS)

    Fletcher, James C. (Inventor); Pratt, J. Richard (Inventor); St.clair, Terry L. (Inventor); Stoakley, Diane M. (Inventor); Burks, Harold D. (Inventor)

    1992-01-01

    A process for preparing polyimides having enhanced melt flow properties is described. The process consists of heating a mixture of a high molecular weight poly-(amic acid) or polyimide with a low molecular weight amic acid or imide additive in the range of 0.05 to 15 percent by weight of additive. The polyimide powders so obtained show improved processability, as evidenced by lower melt viscosity by capillary rheometry. Likewise, films prepared from mixtures of polymers with additives show improved processability with earlier onset of stretching by TMA.

  3. Polyimide processing additives

    NASA Technical Reports Server (NTRS)

    Pratt, J. Richard (Inventor); St.clair, Terry L. (Inventor); Stoakley, Diane M. (Inventor); Burks, Harold D. (Inventor)

    1993-01-01

    A process for preparing polyimides having enhanced melt flow properties is described. The process consists of heating a mixture of a high molecular weight poly-(amic acid) or polyimide with a low molecular weight amic acid or imide additive in the range of 0.05 to 15 percent by weight of the additive. The polyimide powders so obtained show improved processability, as evidenced by lower melt viscosity by capillary rheometry. Likewise, films prepared from mixtures of polymers with additives show improved processability with earlier onset of stretching by TMA.

  4. Additional Types of Neuropathy

    MedlinePlus

    ... A A Listen En Español Additional Types of Neuropathy Charcot's Joint Charcot's Joint, also called neuropathic arthropathy, ... can stop bone destruction and aid healing. Cranial Neuropathy Cranial neuropathy affects the 12 pairs of nerves ...

  5. Food Additives and Hyperkinesis

    ERIC Educational Resources Information Center

    Wender, Ester H.

    1977-01-01

    The hypothesis that food additives are causally associated with hyperkinesis and learning disabilities in children is reviewed, and available data are summarized. Available from: American Medical Association 535 North Dearborn Street Chicago, Illinois 60610. (JG)

  6. Smog control fuel additives

    SciTech Connect

    Lundby, W.

    1993-06-29

    A method is described of controlling, reducing or eliminating, ozone and related smog resulting from photochemical reactions between ozone and automotive or industrial gases comprising the addition of iodine or compounds of iodine to hydrocarbon-base fuels prior to or during combustion in an amount of about 1 part iodine per 240 to 10,000,000 parts fuel, by weight, to be accomplished by: (a) the addition of these inhibitors during or after the refining or manufacturing process of liquid fuels; (b) the production of these inhibitors for addition into fuel tanks, such as automotive or industrial tanks; or (c) the addition of these inhibitors into combustion chambers of equipment utilizing solid fuels for the purpose of reducing ozone.

  7. Additive Manufacturing Infrared Inspection

    NASA Technical Reports Server (NTRS)

    Gaddy, Darrell

    2014-01-01

    Additive manufacturing is a rapid prototyping technology that allows parts to be built in a series of thin layers from plastic, ceramics, and metallics. Metallic additive manufacturing is an emerging form of rapid prototyping that allows complex structures to be built using various metallic powders. Significant time and cost savings have also been observed using the metallic additive manufacturing compared with traditional techniques. Development of the metallic additive manufacturing technology has advanced significantly over the last decade, although many of the techniques to inspect parts made from these processes have not advanced significantly or have limitations. Several external geometry inspection techniques exist such as Coordinate Measurement Machines (CMM), Laser Scanners, Structured Light Scanning Systems, or even traditional calipers and gages. All of the aforementioned techniques are limited to external geometry and contours or must use a contact probe to inspect limited internal dimensions. This presentation will document the development of a process for real-time dimensional inspection technique and digital quality record of the additive manufacturing process using Infrared camera imaging and processing techniques.

  8. Phenylethynyl Containing Reactive Additives

    NASA Technical Reports Server (NTRS)

    Connell, John W. (Inventor); Smith, Joseph G., Jr. (Inventor); Hergenrother, Paul M. (Inventor)

    2002-01-01

    Phenylethynyl containing reactive additives were prepared from aromatic diamine, containing phenylethvnvl groups and various ratios of phthalic anhydride and 4-phenylethynviphthalic anhydride in glacial acetic acid to form the imide in one step or in N-methyl-2-pvrrolidinone to form the amide acid intermediate. The reactive additives were mixed in various amounts (10% to 90%) with oligomers containing either terminal or pendent phenylethynyl groups (or both) to reduce the melt viscosity and thereby enhance processability. Upon thermal cure, the additives react and become chemically incorporated into the matrix and effect an increase in crosslink density relative to that of the host resin. This resultant increase in crosslink density has advantageous consequences on the cured resin properties such as higher glass transition temperature and higher modulus as compared to that of the host resin.

  9. Multifunctional fuel additives

    SciTech Connect

    Baillargeon, D.J.; Cardis, A.B.; Heck, D.B.

    1991-03-26

    This paper discusses a composition comprising a major amount of a liquid hydrocarbyl fuel and a minor low-temperature flow properties improving amount of an additive product of the reaction of a suitable diol and product of a benzophenone tetracarboxylic dianhydride and a long-chain hydrocarbyl aminoalcohol.

  10. Biobased lubricant additives

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Fully biobased lubricants are those formulated using all biobased ingredients, i.e. biobased base oils and biobased additives. Such formulations provide the maximum environmental, safety, and economic benefits expected from a biobased product. Currently, there are a number of biobased base oils that...

  11. An Additive Manufacturing Test Artifact.

    PubMed

    Moylan, Shawn; Slotwinski, John; Cooke, April; Jurrens, Kevin; Donmez, M Alkan

    2014-01-01

    A test artifact, intended for standardization, is proposed for the purpose of evaluating the performance of additive manufacturing (AM) systems. A thorough analysis of previously proposed AM test artifacts as well as experience with machining test artifacts have inspired the design of the proposed test artifact. This new artifact is designed to provide a characterization of the capabilities and limitations of an AM system, as well as to allow system improvement by linking specific errors measured in the test artifact to specific sources in the AM system. The proposed test artifact has been built in multiple materials using multiple AM technologies. The results of several of the builds are discussed, demonstrating how the measurement results can be used to characterize and improve a specific AM system. PMID:26601039

  12. An Additive Manufacturing Test Artifact

    PubMed Central

    Moylan, Shawn; Slotwinski, John; Cooke, April; Jurrens, Kevin; Donmez, M Alkan

    2014-01-01

    A test artifact, intended for standardization, is proposed for the purpose of evaluating the performance of additive manufacturing (AM) systems. A thorough analysis of previously proposed AM test artifacts as well as experience with machining test artifacts have inspired the design of the proposed test artifact. This new artifact is designed to provide a characterization of the capabilities and limitations of an AM system, as well as to allow system improvement by linking specific errors measured in the test artifact to specific sources in the AM system. The proposed test artifact has been built in multiple materials using multiple AM technologies. The results of several of the builds are discussed, demonstrating how the measurement results can be used to characterize and improve a specific AM system. PMID:26601039

  13. An Additive Manufacturing Test Artifact.

    PubMed

    Moylan, Shawn; Slotwinski, John; Cooke, April; Jurrens, Kevin; Donmez, M Alkan

    2014-01-01

    A test artifact, intended for standardization, is proposed for the purpose of evaluating the performance of additive manufacturing (AM) systems. A thorough analysis of previously proposed AM test artifacts as well as experience with machining test artifacts have inspired the design of the proposed test artifact. This new artifact is designed to provide a characterization of the capabilities and limitations of an AM system, as well as to allow system improvement by linking specific errors measured in the test artifact to specific sources in the AM system. The proposed test artifact has been built in multiple materials using multiple AM technologies. The results of several of the builds are discussed, demonstrating how the measurement results can be used to characterize and improve a specific AM system.

  14. Design Methodology of an Equalizer for Unipolar Non Return to Zero Binary Signals in the Presence of Additive White Gaussian Noise Using a Time Delay Neural Network on a Field Programmable Gate Array

    PubMed Central

    Pérez Suárez, Santiago T.; Travieso González, Carlos M.; Alonso Hernández, Jesús B.

    2013-01-01

    This article presents a design methodology for designing an artificial neural network as an equalizer for a binary signal. Firstly, the system is modelled in floating point format using Matlab. Afterward, the design is described for a Field Programmable Gate Array (FPGA) using fixed point format. The FPGA design is based on the System Generator from Xilinx, which is a design tool over Simulink of Matlab. System Generator allows one to design in a fast and flexible way. It uses low level details of the circuits and the functionality of the system can be fully tested. System Generator can be used to check the architecture and to analyse the effect of the number of bits on the system performance. Finally the System Generator design is compiled for the Xilinx Integrated System Environment (ISE) and the system is described using a hardware description language. In ISE the circuits are managed with high level details and physical performances are obtained. In the Conclusions section, some modifications are proposed to improve the methodology and to ensure portability across FPGA manufacturers.

  15. Vinyl capped addition polyimides

    NASA Technical Reports Server (NTRS)

    Vannucci, Raymond D. (Inventor); Malarik, Diane C. (Inventor); Delvigs, Peter (Inventor)

    1991-01-01

    Polyimide resins (PMR) are generally useful where high strength and temperature capabilities are required (at temperatures up to about 700 F). Polyimide resins are particularly useful in applications such as jet engine compressor components, for example, blades, vanes, air seals, air splitters, and engine casing parts. Aromatic vinyl capped addition polyimides are obtained by reacting a diamine, an ester of tetracarboxylic acid, and an aromatic vinyl compound. Low void materials with improved oxidative stability when exposed to 700 F air may be fabricated as fiber reinforced high molecular weight capped polyimide composites. The aromatic vinyl capped polyimides are provided with a more aromatic nature and are more thermally stable than highly aliphatic, norbornenyl-type end-capped polyimides employed in PMR resins. The substitution of aromatic vinyl end-caps for norbornenyl end-caps in addition polyimides results in polymers with improved oxidative stability.

  16. Tackifier for addition polyimides

    NASA Technical Reports Server (NTRS)

    Butler, J. M.; St.clair, T. L.

    1980-01-01

    A modification to the addition polyimide, LaRC-160, was prepared to improve tack and drape and increase prepeg out-time. The essentially solventless, high viscosity laminating resin is synthesized from low cost liquid monomers. The modified version takes advantage of a reactive, liquid plasticizer which is used in place of solvent and helps solve a major problem of maintaining good prepeg tack and drape, or the ability of the prepeg to adhere to adjacent plies and conform to a desired shape during the lay up process. This alternate solventless approach allows both longer life of the polymer prepeg and the processing of low void laminates. This approach appears to be applicable to all addition polyimide systems.

  17. Electrophilic addition of astatine

    SciTech Connect

    Norseev, Yu.V.; Vasaros, L.; Nhan, D.D.; Huan, N.K.

    1988-03-01

    It has been shown for the first time that astatine is capable of undergoing addition reactions to unsaturated hydrocarbons. A new compound of astatine, viz., ethylene astatohydrin, has been obtained, and its retention numbers of squalane, Apiezon, and tricresyl phosphate have been found. The influence of various factors on the formation of ethylene astatohydrin has been studied. It has been concluded on the basis of the results obtained that the univalent cations of astatine in an acidic medium is protonated hypoastatous acid.

  18. Functional Generalized Additive Models.

    PubMed

    McLean, Mathew W; Hooker, Giles; Staicu, Ana-Maria; Scheipl, Fabian; Ruppert, David

    2014-01-01

    We introduce the functional generalized additive model (FGAM), a novel regression model for association studies between a scalar response and a functional predictor. We model the link-transformed mean response as the integral with respect to t of F{X(t), t} where F(·,·) is an unknown regression function and X(t) is a functional covariate. Rather than having an additive model in a finite number of principal components as in Müller and Yao (2008), our model incorporates the functional predictor directly and thus our model can be viewed as the natural functional extension of generalized additive models. We estimate F(·,·) using tensor-product B-splines with roughness penalties. A pointwise quantile transformation of the functional predictor is also considered to ensure each tensor-product B-spline has observed data on its support. The methods are evaluated using simulated data and their predictive performance is compared with other competing scalar-on-function regression alternatives. We illustrate the usefulness of our approach through an application to brain tractography, where X(t) is a signal from diffusion tensor imaging at position, t, along a tract in the brain. In one example, the response is disease-status (case or control) and in a second example, it is the score on a cognitive test. R code for performing the simulations and fitting the FGAM can be found in supplemental materials available online.

  19. 40 CFR 79.31 - Additives.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... produced or sold for use in motor vehicle gasoline and/or motor vehicle diesel fuel are hereby designated... additive on all emissions; (5) Toxicity and any other public health or welfare effects of the...

  20. 40 CFR 79.31 - Additives.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... produced or sold for use in motor vehicle gasoline and/or motor vehicle diesel fuel are hereby designated... additive on all emissions; (5) Toxicity and any other public health or welfare effects of the...

  1. 40 CFR 79.31 - Additives.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... produced or sold for use in motor vehicle gasoline and/or motor vehicle diesel fuel are hereby designated... additive on all emissions; (5) Toxicity and any other public health or welfare effects of the...

  2. 40 CFR 79.31 - Additives.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... produced or sold for use in motor vehicle gasoline and/or motor vehicle diesel fuel are hereby designated... additive on all emissions; (5) Toxicity and any other public health or welfare effects of the...

  3. 40 CFR 79.31 - Additives.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... produced or sold for use in motor vehicle gasoline and/or motor vehicle diesel fuel are hereby designated... additive on all emissions; (5) Toxicity and any other public health or welfare effects of the...

  4. Performance Boosting Additive

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Mainstream Engineering Corporation was awarded Phase I and Phase II contracts from Goddard Space Flight Center's Small Business Innovation Research (SBIR) program in early 1990. With support from the SBIR program, Mainstream Engineering Corporation has developed a unique low cost additive, QwikBoost (TM), that increases the performance of air conditioners, heat pumps, refrigerators, and freezers. Because of the energy and environmental benefits of QwikBoost, Mainstream received the Tibbetts Award at a White House Ceremony on October 16, 1997. QwikBoost was introduced at the 1998 International Air Conditioning, Heating, and Refrigeration Exposition. QwikBoost is packaged in a handy 3-ounce can (pressurized with R-134a) and will be available for automotive air conditioning systems in summer 1998.

  5. Sewage sludge additive

    NASA Technical Reports Server (NTRS)

    Kalvinskas, J. J.; Mueller, W. A.; Ingham, J. D. (Inventor)

    1980-01-01

    The additive is for a raw sewage treatment process of the type where settling tanks are used for the purpose of permitting the suspended matter in the raw sewage to be settled as well as to permit adsorption of the dissolved contaminants in the water of the sewage. The sludge, which settles down to the bottom of the settling tank is extracted, pyrolyzed and activated to form activated carbon and ash which is mixed with the sewage prior to its introduction into the settling tank. The sludge does not provide all of the activated carbon and ash required for adequate treatment of the raw sewage. It is necessary to add carbon to the process and instead of expensive commercial carbon, coal is used to provide the carbon supplement.

  6. The Additive Coloration of Alkali Halides

    ERIC Educational Resources Information Center

    Jirgal, G. H.; and others

    1969-01-01

    Describes the construction and use of an inexpensive, vacuum furnace designed to produce F-centers in alkali halide crystals by additive coloration. The method described avoids corrosion or contamination during the coloration process. Examination of the resultant crystals is discussed and several experiments using additively colored crystals are…

  7. [Safety of food additives in Japan].

    PubMed

    Ito, Sumio

    2011-01-01

    Recently, many accidents relating to food happened in Japan. The consumer's distrust for food, food companies, and the administration is increasing. The consumer especially has an extreme refusal feeling for chemicals such as food additives and agricultural chemicals, and begins to request agricultural chemical-free vegetables and food additive-free food. Food companies also state no agricultural chemicals and no food additives to correspond with consumers' request and aim at differentiating. The food additive is that the Ministry of Health, Labour and Welfare specifies the one that person's health might not be ruined by providing for Food Sanitation Law Article 10 in our country. The standard for food additives and standard for use of food additives are provided according to regulations of Food Sanitation Law Article 11. Therefore, it is thought that the food additive used is safe now. Then, it reports on the procedure and the safety examination, etc. in our country for designation for food additive this time.

  8. Additive lattice kirigami

    PubMed Central

    Castle, Toen; Sussman, Daniel M.; Tanis, Michael; Kamien, Randall D.

    2016-01-01

    Kirigami uses bending, folding, cutting, and pasting to create complex three-dimensional (3D) structures from a flat sheet. In the case of lattice kirigami, this cutting and rejoining introduces defects into an underlying 2D lattice in the form of points of nonzero Gaussian curvature. A set of simple rules was previously used to generate a wide variety of stepped structures; we now pare back these rules to their minimum. This allows us to describe a set of techniques that unify a wide variety of cut-and-paste actions under the rubric of lattice kirigami, including adding new material and rejoining material across arbitrary cuts in the sheet. We also explore the use of more complex lattices and the different structures that consequently arise. Regardless of the choice of lattice, creating complex structures may require multiple overlapping kirigami cuts, where subsequent cuts are not performed on a locally flat lattice. Our additive kirigami method describes such cuts, providing a simple methodology and a set of techniques to build a huge variety of complex 3D shapes. PMID:27679822

  9. Additive lattice kirigami

    PubMed Central

    Castle, Toen; Sussman, Daniel M.; Tanis, Michael; Kamien, Randall D.

    2016-01-01

    Kirigami uses bending, folding, cutting, and pasting to create complex three-dimensional (3D) structures from a flat sheet. In the case of lattice kirigami, this cutting and rejoining introduces defects into an underlying 2D lattice in the form of points of nonzero Gaussian curvature. A set of simple rules was previously used to generate a wide variety of stepped structures; we now pare back these rules to their minimum. This allows us to describe a set of techniques that unify a wide variety of cut-and-paste actions under the rubric of lattice kirigami, including adding new material and rejoining material across arbitrary cuts in the sheet. We also explore the use of more complex lattices and the different structures that consequently arise. Regardless of the choice of lattice, creating complex structures may require multiple overlapping kirigami cuts, where subsequent cuts are not performed on a locally flat lattice. Our additive kirigami method describes such cuts, providing a simple methodology and a set of techniques to build a huge variety of complex 3D shapes.

  10. Bespoke contrast-matched diblock copolymer nanoparticles enable the rational design of highly transparent Pickering double emulsions† †Electronic supplementary information (ESI) available: GPC chromatograms, additional transmission electron micrographs, digital photographs, visible absorption spectra and laser diffraction data, further optical and fluorescence micrographs. See DOI: 10.1039/c6nr03856e Click here for additional data file.

    PubMed Central

    Thompson, Kate L.; Derry, Matthew J.; Warren, Nicholas J.; Ratcliffe, Liam P. D.; Williams, Clive N.; Brown, Steven L.

    2016-01-01

    We report the preparation of highly transparent oil-in-water Pickering emulsions using contrast-matched organic nanoparticles. This is achieved via addition of judicious amounts of either sucrose or glycerol to an aqueous dispersion of poly(glycerol monomethacrylate)56–poly(2,2,2-trifluoroethyl methacrylate)500 [PGMA–PTFEMA] diblock copolymer nanoparticles prior to high shear homogenization with an equal volume of n-dodecane. The resulting Pickering emulsions comprise polydisperse n-dodecane droplets of 20–100 μm diameter and exhibit up to 96% transmittance across the visible spectrum. In contrast, control experiments using non-contrast-matched poly(glycerol monomethacrylate)56–poly(benzyl methacrylate)300 [PGMA56–PBzMA300] diblock copolymer nanoparticles as a Pickering emulsifier only produced conventional highly turbid emulsions. Thus contrast-matching of the two immiscible phases is a necessary but not sufficient condition for the preparation of highly transparent Pickering emulsions: it is essential to use isorefractive nanoparticles in order to minimize light scattering. Furthermore, highly transparent oil-in-water-in-oil Pickering double emulsions can be obtained by homogenizing the contrast-matched oil-in-water Pickering emulsion prepared using the PGMA56–PTFEMA500 nanoparticles with a contrast-matched dispersion of hydrophobic poly(lauryl methacrylate)39–poly(2,2,2-trifluoroethyl methacrylate)800 [PLMA39–PTFEMA800] diblock copolymer nanoparticles in n-dodecane. Finally, we show that an isorefractive oil-in-water Pickering emulsion enables fluorescence spectroscopy to be used to monitor the transport of water-insoluble small molecules (pyrene and benzophenone) between n-dodecane droplets. Such transport is significantly less efficient than that observed for the equivalent isorefractive surfactant-stabilized emulsion. Conventional turbid emulsions do not enable such a comparison to be made because the intense light scattering leads to

  11. Design of underwater superoleophobic TiO{sub 2} coatings with additional photo-induced self-cleaning properties by one-step route bio-inspired from fish scales

    SciTech Connect

    Wang, Hao; Guo, Zhiguang

    2014-05-05

    Self-cleaning properties inspired by the structures and functions of some creatures are of great interest since the late 20th century. In this paper, TiO{sub 2} coatings with hierarchical rutile TiO{sub 2} flowers on fluorine-doped tin oxide substrate are fabricated through a simple one-step hydrothermal method. The flower-like coatings exhibit superhydrophilicity in air and superoleophobicity underwater with a contact angle as high as 157°, presenting good underwater self-cleaning performance. In addition, when contaminated by oleic acid, the as-prepared TiO{sub 2} coatings also exhibit excellent photocatalytic capability under ultraviolet irradiation, which demonstrated self-cleaning properties in a different way. This self-cleaning film provides a good strategy for some industrial and ocean applications.

  12. Design of thiol–ene photoclick hydrogels using facile techniques for cell culture applications† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c4bm00187g Click here for additional data file.

    PubMed Central

    Sawicki, Lisa A.

    2014-01-01

    Thiol–ene ‘click’ chemistries have been widely used in biomaterials applications, including drug delivery, tissue engineering, and controlled cell culture, owing to their rapid, cytocompatible, and often orthogonal reactivity. In particular, hydrogel-based biomaterials formed by photoinitiated thiol–ene reactions afford spatiotemporal control over the biochemical and biomechanical properties of the network for creating synthetic materials that mimic the extracellular matrix or enable controlled drug release. However, the use of charged peptides functionalized with cysteines, which can form disulfides prior to reaction, and vinyl monomers that require multistep syntheses and contain ester bonds, may lead to undesired inhomogeneity or degradation under cell culture conditions. Here, we designed a thiol–ene hydrogel formed by the reaction of allyloxycarbonyl-functionalized peptides and thiol-functionalized poly(ethylene glycol). Hydrogels were polymerized by free radical initiation under cytocompatible doses of long wavelength ultraviolet light in the presence of water-soluble photoinitiators (lithium acylphosphinate, LAP, and 2-hydroxy-1-[4-(2-hydroxyethoxy)phenyl]-2-methyl-1-propanone, Irgacure 2959). Mechanical properties of these hydrogels were controlled by varying the monomer concentration to mimic a range of soft tissue environments, and hydrogel stability in cell culture medium was observed over weeks. Patterns of biochemical cues were created within the hydrogels post-formation and confirmed through the incorporation of fluorescently-labeled peptides and Ellman's assay to detect free thiols. Human mesenchymal stem cells remained viable after encapsulation and subsequent photopatterning, demonstrating the utility of the monomers and hydrogels for three-dimensional cell culture. This facile approach enables the formation and characterization of hydrogels with well-defined, spatially-specific properties and expands the suite of monomers available for

  13. Dynamical systems techniques for designing libration point orbits in proximity of highly-inhomogeneous planetary satellites: Application to the Mars-Phobos elliptic three-body problem with additional gravity harmonics

    NASA Astrophysics Data System (ADS)

    Zamaro, Mattia; Biggs, James D.

    2014-12-01

    The orbital dynamics around the Libration points of the classical circular restricted three-body problem (CR3BP) have been investigated in detail: in the last few decades, dynamical systems theory has provided invaluable analytical and numerical tools for understanding the dynamics of Libration Point Orbits (LPOs). The aim of this paper is to extend the model of the CR3BP to derive the LPOs in the vicinity of the Martian moon Phobos, which is becoming an appealing destination for scientific missions. The case of Phobos is particularly extreme, since the combination of both small mass-ratio and length-scale moves the collinear Libration manifold close to the moon's surface. Thus, a model of this system must consider additional dynamical perturbations, in particular the complete gravity field of Phobos, which is highly-inhomogeneous. This is accomplished using a spherical harmonics series expansion, deriving an enhanced elliptic three-body model. In this paper, we show how methodologies from dynamical systems theory are applied in differential correction continuation schemes to this proposed nonlinear model of the dynamics near Phobos, to derive the structure of the dynamical substitutes of the LPOs in this new system. Results obtained show that the structure of the LPOs differs substantially from the classical case without harmonics. The proposed methodology allows us to identify natural periodic and quasi-periodic orbits that would provide unique low-cost opportunities for close-range observations around Phobos and high-performance landing/take-off pathways to and from Phobos' surface, which could be exploited in upcoming missions targeting the exploration of this Martian moon.

  14. Neutron Characterization for Additive Manufacturing

    NASA Technical Reports Server (NTRS)

    Watkins, Thomas; Bilheux, Hassina; An, Ke; Payzant, Andrew; DeHoff, Ryan; Duty, Chad; Peter, William; Blue, Craig; Brice, Craig A.

    2013-01-01

    Oak Ridge National Laboratory (ORNL) is leveraging decades of experience in neutron characterization of advanced materials together with resources such as the Spallation Neutron Source (SNS) and the High Flux Isotope Reactor (HFIR) shown in Fig. 1 to solve challenging problems in additive manufacturing (AM). Additive manufacturing, or three-dimensional (3-D) printing, is a rapidly maturing technology wherein components are built by selectively adding feedstock material at locations specified by a computer model. The majority of these technologies use thermally driven phase change mechanisms to convert the feedstock into functioning material. As the molten material cools and solidifies, the component is subjected to significant thermal gradients, generating significant internal stresses throughout the part (Fig. 2). As layers are added, inherent residual stresses cause warping and distortions that lead to geometrical differences between the final part and the original computer generated design. This effect also limits geometries that can be fabricated using AM, such as thin-walled, high-aspect- ratio, and overhanging structures. Distortion may be minimized by intelligent toolpath planning or strategic placement of support structures, but these approaches are not well understood and often "Edisonian" in nature. Residual stresses can also impact component performance during operation. For example, in a thermally cycled environment such as a high-pressure turbine engine, residual stresses can cause components to distort unpredictably. Different thermal treatments on as-fabricated AM components have been used to minimize residual stress, but components still retain a nonhomogeneous stress state and/or demonstrate a relaxation-derived geometric distortion. Industry, federal laboratory, and university collaboration is needed to address these challenges and enable the U.S. to compete in the global market. Work is currently being conducted on AM technologies at the ORNL

  15. Additives in fibers and fabrics.

    PubMed

    Barker, R H

    1975-06-01

    The additives and contaminants which occur in textile fibers vary widely, depending on the type of fiber and the pretreatment which it has received. Synthetic fibers such as nylon and polyester contain trace amounts of contaminants such as catalysts and catalyst deactivators which remain after the synthesis of the basic polymers. In addition, there are frequently a number of materials which are added to perform specific functions in almost all man-made fibers. Examples of these would include traces of metals or metal salts used as tracers for identification of specific lots of fiber, TiO2 or similar materials added as delustrants, and a host of organic species added for such special purposes as antistatic agents or flame retardants. There may also be considerable quantities of residual monomer or small oligomers dissolved in the polymer matrix. The situation becomes even more complex after the fibers are converted into fabric form. Numerous materials are applied at various stages of fabric preparation to act as lubricants, sizing agents, antistats, bleaches, and wetting agents to facilitate the processing, but these are normally removed before the fabric reaches the cutters of the ultimate consumers and therefore usually do not constitute potential hazards. However, there are many other chemical agents which are frequently added during the later stages of fabric preparation and which are not designed to be removed. Aside from dyes and printing pigments, the most common additive for apparel fabrics is a durable press treatment. This generally involves the use of materials capable of crosslinking cellulosics by reacting through such functions as N-methylolated amides or related compounds such as ureas and carbamates. These materials pose some potential hazards due to both the nitrogenous bases and the formaldehyde which they usually release. There is usually also some residual catalyst in fabrics which have received such treatments. Other types of chemical treatments

  16. Additives in fibers and fabrics.

    PubMed Central

    Barker, R H

    1975-01-01

    The additives and contaminants which occur in textile fibers vary widely, depending on the type of fiber and the pretreatment which it has received. Synthetic fibers such as nylon and polyester contain trace amounts of contaminants such as catalysts and catalyst deactivators which remain after the synthesis of the basic polymers. In addition, there are frequently a number of materials which are added to perform specific functions in almost all man-made fibers. Examples of these would include traces of metals or metal salts used as tracers for identification of specific lots of fiber, TiO2 or similar materials added as delustrants, and a host of organic species added for such special purposes as antistatic agents or flame retardants. There may also be considerable quantities of residual monomer or small oligomers dissolved in the polymer matrix. The situation becomes even more complex after the fibers are converted into fabric form. Numerous materials are applied at various stages of fabric preparation to act as lubricants, sizing agents, antistats, bleaches, and wetting agents to facilitate the processing, but these are normally removed before the fabric reaches the cutters of the ultimate consumers and therefore usually do not constitute potential hazards. However, there are many other chemical agents which are frequently added during the later stages of fabric preparation and which are not designed to be removed. Aside from dyes and printing pigments, the most common additive for apparel fabrics is a durable press treatment. This generally involves the use of materials capable of crosslinking cellulosics by reacting through such functions as N-methylolated amides or related compounds such as ureas and carbamates. These materials pose some potential hazards due to both the nitrogenous bases and the formaldehyde which they usually release. There is usually also some residual catalyst in fabrics which have received such treatments. Other types of chemical treatments

  17. 3D-additive manufactured optical mount

    NASA Astrophysics Data System (ADS)

    Mammini, Paul V.; Ciscel, David; Wooten, John

    2015-09-01

    The Area Defense Anti-Munitions (ADAM) is a low cost and effective high power laser weapon system. It's designed to address and negate important threats such as short-range rockets, UAVs, and small boats. Many critical optical components operate in the system. The optics and mounts must accommodate thermal and mechanical stresses, plus maintain an exceptional wave front during operation. Lockheed Martin Space Systems Company (LMSSC) developed, designed, and currently operates ADAM. This paper covers the design and development of a key monolithic, flexured, titanium mirror mount that was manufactured by CalRAM using additive processes.

  18. Additive Manufacturing: From Rapid Prototyping to Flight

    NASA Technical Reports Server (NTRS)

    Prater, Tracie

    2015-01-01

    Additive manufacturing (AM) offers tremendous promise for the rocket propulsion community. Foundational work must be performed to ensure the safe performance of AM parts. Government, industry, and academia must collaborate in the characterization, design, modeling, and process control to accelerate the certification of AM parts for human-rated flight.

  19. Designing Skateboards

    ERIC Educational Resources Information Center

    Howard, Jim

    2009-01-01

    Having students buy in to the relevance of a lesson is always a challenge, even in a graphic design classroom. In this article, the author describes an activity on designing skateboards. The most successful element of this project was the addition of assessment and criticism from an outside audience. The inclusion of an outside audience upped the…

  20. Incorporation of additives into polymers

    DOEpatents

    McCleskey, T. Mark; Yates, Matthew Z.

    2003-07-29

    There has been invented a method for incorporating additives into polymers comprising: (a) forming an aqueous or alcohol-based colloidal system of the polymer; (b) emulsifying the colloidal system with a compressed fluid; and (c) contacting the colloidal polymer with the additive in the presence of the compressed fluid. The colloidal polymer can be contacted with the additive by having the additive in the compressed fluid used for emulsification or by adding the additive to the colloidal system before or after emulsification with the compressed fluid. The invention process can be carried out either as a batch process or as a continuous on-line process.

  1. 28 CFR 571.72 - Additional designated offenses.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... commit sodomy); (10) 134-R1 (Indecent act with a minor); (11) 134-R3 (Indecent language to a minor); (12... includes assault with the intent to commit first degree sexual abuse, second degree sexual abuse, or child... prostitution; harboring such child); (7) § 22-4102 (First degree sexual abuse); (8) § 22-4103 (Second...

  2. 28 CFR 571.72 - Additional designated offenses.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ....S.C. 4042(c): (a) Any offense under the law of any jurisdiction that involved: (1) Engaging in... the mentally ill, rape by administering a drug or substance); (4) Any sexual act or contact not... Incident Based Reporting System (DIBRS) Code offenses under the Uniform Code of Military Justice: (1)...

  3. 28 CFR 571.72 - Additional designated offenses.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ....S.C. 4042(c): (a) Any offense under the law of any jurisdiction that involved: (1) Engaging in... the mentally ill, rape by administering a drug or substance); (4) Any sexual act or contact not... Incident Based Reporting System (DIBRS) Code offenses under the Uniform Code of Military Justice: (1)...

  4. 28 CFR 571.72 - Additional designated offenses.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ....S.C. 4042(c): (a) Any offense under the law of any jurisdiction that involved: (1) Engaging in... the mentally ill, rape by administering a drug or substance); (4) Any sexual act or contact not... Incident Based Reporting System (DIBRS) Code offenses under the Uniform Code of Military Justice: (1)...

  5. 28 CFR 571.72 - Additional designated offenses.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ....S.C. 4042(c): (a) Any offense under the law of any jurisdiction that involved: (1) Engaging in... the mentally ill, rape by administering a drug or substance); (4) Any sexual act or contact not... Incident Based Reporting System (DIBRS) Code offenses under the Uniform Code of Military Justice: (1)...

  6. [Patch-testing methods: additional specialised or additional series].

    PubMed

    Cleenewerck, M-B

    2009-01-01

    The tests in the European standard battery must occasionally be supplemented by specialised or additional batteries, particularly where the contact allergy is thought to be of occupational origin. These additional batteries cover all allergens associated with various professional activities (hairdressing, baking, dentistry, printing, etc.) and with different classes of materials and chemical products (glue, plastic, rubber...). These additional tests may also include personal items used by patients on a daily basis such as cosmetics, shoes, plants, textiles and so on.

  7. Effect of additives on protein aggregation.

    PubMed

    Hamada, Hiroyuki; Arakawa, Tsutomu; Shiraki, Kentaro

    2009-06-01

    This paper overviews solution additives that affect protein stability and aggregation during refolding, heating, and freezing processes. Solution additives are mainly grouped into two classes, i.e., protein denaturants and stabilizers. The former includes guanidine, urea, strong ionic detergents, and certain chaotropic salts; the latter includes certain amino acids, sugars, polyhydric alcohols, osmolytes, and kosmotropic salts. However, there are solution additives that are not unambiguously placed into these two classes, including arginine, certain divalent cation salts (e.g., MgCl(2)) and certain polyhydric alcohols (e.g., ethylene glycol). Certain non-ionic or non-detergent surfactants, ionic liquids, amino acid derivatives, polyamines, and certain amphiphilic polymers may belong to this class. They have marginal effects on protein structure and stability, but are able to disrupt protein interactions. Information on additives that do not catalyze chemical reactions nor affect protein functions helps us to design protein solutions for increased stability or reduced aggregation. PMID:19519415

  8. Information Design: A Bibliography.

    ERIC Educational Resources Information Center

    Albers, Michael J.; Lisberg, Beth Conney

    2000-01-01

    Presents a 17-item annotated list of essential books on information design chosen by members of the InfoDesign e-mail list. Includes a 113-item unannotated bibliography of additional works, on topics of creativity and critical thinking; visual thinking; graphic design; infographics; information design; instructional design; interface design;…

  9. Breaking Barriers in Polymer Additive Manufacturing

    SciTech Connect

    Love, Lonnie J; Duty, Chad E; Post, Brian K; Lind, Randall F; Lloyd, Peter D; Kunc, Vlastimil; Peter, William H; Blue, Craig A

    2015-01-01

    Additive Manufacturing (AM) enables the creation of complex structures directly from a computer-aided design (CAD). There are limitations that prevent the technology from realizing its full potential. AM has been criticized for being slow and expensive with limited build size. Oak Ridge National Laboratory (ORNL) has developed a large scale AM system that improves upon each of these areas by more than an order of magnitude. The Big Area Additive Manufacturing (BAAM) system directly converts low cost pellets into a large, three-dimensional part at a rate exceeding 25 kg/h. By breaking these traditional barriers, it is possible for polymer AM to penetrate new manufacturing markets.

  10. Enantioselective Michael Addition of Water

    PubMed Central

    Chen, Bi-Shuang; Resch, Verena; Otten, Linda G; Hanefeld, Ulf

    2015-01-01

    The enantioselective Michael addition using water as both nucleophile and solvent has to date proved beyond the ability of synthetic chemists. Herein, the direct, enantioselective Michael addition of water in water to prepare important β-hydroxy carbonyl compounds using whole cells of Rhodococcus strains is described. Good yields and excellent enantioselectivities were achieved with this method. Deuterium labeling studies demonstrate that a Michael hydratase catalyzes the water addition exclusively with anti-stereochemistry. PMID:25529526

  11. Enantioselective Michael addition of water.

    PubMed

    Chen, Bi-Shuang; Resch, Verena; Otten, Linda G; Hanefeld, Ulf

    2015-02-01

    The enantioselective Michael addition using water as both nucleophile and solvent has to date proved beyond the ability of synthetic chemists. Herein, the direct, enantioselective Michael addition of water in water to prepare important β-hydroxy carbonyl compounds using whole cells of Rhodococcus strains is described. Good yields and excellent enantioselectivities were achieved with this method. Deuterium labeling studies demonstrate that a Michael hydratase catalyzes the water addition exclusively with anti-stereochemistry.

  12. Gasoline additives, emissions, and performance

    SciTech Connect

    1995-12-31

    The papers included in this publication deal with the influence of fuel, additive, and hardware changes on a variety of vehicle performance characteristics. Advanced techniques for measuring these performance parameters are also described. Contents include: Fleet test evaluation of gasoline additives for intake valve and combustion chamber deposit clean up; A technique for evaluating octane requirement additives in modern engines on dynamometer test stands; A fleet test of two additive technologies comparing their effects on tailpipe emissions; Investigation into the vehicle exhaust emissions of high percentage ethanol blends; Variability in hydrocarbon speciation measurements at low emission (ULEV) levels; and more.

  13. Color Addition and Subtraction Apps

    ERIC Educational Resources Information Center

    Ruiz, Frances; Ruiz, Michael J.

    2015-01-01

    Color addition and subtraction apps in HTML5 have been developed for students as an online hands-on experience so that they can more easily master principles introduced through traditional classroom demonstrations. The evolution of the additive RGB color model is traced through the early IBM color adapters so that students can proceed step by step…

  14. Reversible Michael additions: covalent inhibitors and prodrugs.

    PubMed

    Johansson, Martin H

    2012-11-01

    Covalent inhibition is an efficient molecular mechanism for inhibiting enzymes or modulating the function of proteins and is found in the action of many drugs and biologically active natural products. However, it is has been less appreciated that the formation of covalent bonds can be reversible or irreversible. This review focuses on biologically active compounds that are Michael acceptors and how the reversible nature of the Michael addition reaction influences biological activity and how this can be exploited in designing prodrugs.

  15. Simulation method for evaluating progressive addition lenses.

    PubMed

    Qin, Linling; Qian, Lin; Yu, Jingchi

    2013-06-20

    Since progressive addition lenses (PALs) are currently state-of-the-art in multifocal correction for presbyopia, it is important to study the methods for evaluating PALs. A nonoptical simulation method used to accurately characterize PALs during the design and optimization process is proposed in this paper. It involves the direct calculation of each surface of the lens according to the lens heights of front and rear surfaces. The validity of this simulation method for the evaluation of PALs is verified by the good agreement with Rotlex method. In particular, the simulation with a "correction action" included into the design process is potentially a useful method with advantages of time-saving, convenience, and accuracy. Based on the eye-plus-lens model, which is established through an accurate ray tracing calculation along the gaze direction, the method can find an excellent application in actually evaluating the wearer performance for optimal design of more comfortable, satisfactory, and personalized PALs. PMID:23842170

  16. Evaluation of advanced polymers for additive manufacturing

    SciTech Connect

    Rios, Orlando; Morrison, Crystal

    2015-09-01

    The goal of this Manufacturing Demonstration Facility (MDF) technical collaboration project between Oak Ridge National Laboratory (ORNL) and PPG Industries, Inc. was to evaluate the feasibility of using conventional coatings chemistry and technology to build up material layer-by-layer. The PPG-ORNL study successfully demonstrated that polymeric coatings formulations may overcome many limitations of common thermoplastics used in additive manufacturing (AM), allow lightweight nozzle design for material deposition and increase build rate. The materials effort focused on layer-by-layer deposition of coatings with each layer fusing together. The combination of materials and deposition results in an additively manufactured build that has sufficient mechanical properties to bear the load of additional layers, yet is capable of bonding across the z-layers to improve build direction strength. The formulation properties were tuned to enable a novel, high-throughput deposition method that is highly scalable, compatible with high loading of reinforcing fillers, and is inherently low-cost.

  17. Additive manufacturing of materials: Opportunities and challenges

    SciTech Connect

    Babu, Sudarsanam Suresh; Love, Lonnie J.; Dehoff, Ryan R.; Peter, William H.; Watkins, Thomas R.; Pannala, Sreekanth

    2015-11-01

    Additive manufacturing (also known as 3D printing) is considered a disruptive technology for producing components with topologically optimized complex geometries as well as functionalities that are not achievable by traditional methods. The realization of the full potential of 3D printing is stifled by a lack of computational design tools, generic material feedstocks, techniques for monitoring thermomechanical processes under in situ conditions, and especially methods for minimizing anisotropic static and dynamic properties brought about by microstructural heterogeneity. In this paper, we discuss the role of interdisciplinary research involving robotics and automation, process control, multiscale characterization of microstructure and properties, and high-performance computational tools to address each of these challenges. In addition, emerging pathways to scale up additive manufacturing of structural materials to large sizes (>1 m) and higher productivities (5–20 kg/h) while maintaining mechanical performance and geometrical flexibility are also discussed.

  18. Additive manufacturing of materials: Opportunities and challenges

    DOE PAGES

    Babu, Sudarsanam Suresh; Love, Lonnie J.; Dehoff, Ryan R.; Peter, William H.; Watkins, Thomas R.; Pannala, Sreekanth

    2015-11-01

    Additive manufacturing (also known as 3D printing) is considered a disruptive technology for producing components with topologically optimized complex geometries as well as functionalities that are not achievable by traditional methods. The realization of the full potential of 3D printing is stifled by a lack of computational design tools, generic material feedstocks, techniques for monitoring thermomechanical processes under in situ conditions, and especially methods for minimizing anisotropic static and dynamic properties brought about by microstructural heterogeneity. In this paper, we discuss the role of interdisciplinary research involving robotics and automation, process control, multiscale characterization of microstructure and properties, and high-performancemore » computational tools to address each of these challenges. In addition, emerging pathways to scale up additive manufacturing of structural materials to large sizes (>1 m) and higher productivities (5–20 kg/h) while maintaining mechanical performance and geometrical flexibility are also discussed.« less

  19. Teebi hypertelorism syndrome: additional cases.

    PubMed

    Machado-Paula, Ligiane Alves; Guion-Almeida, Maria Leine

    2003-03-01

    We report on two unrelated Brazilian boys who have craniofacial and digital anomalies resembling those reported with Teebi hypertelorism syndrome. Additional features such as cleft lip and palate, large uvula, atypical chin and abnormal scapulae were observed.

  20. Polyolefins as additives in plastics

    SciTech Connect

    Deanin, R.D.

    1993-12-31

    Polyolefins are not only major commodity plastics - they are also very useful as additives, both in other polyolefins and also in other types of plastics. This review covers ethylene, propylene, butylene and isobutylene polymers, in blends with each other, and as additives to natural rubber, styrene/butadiene rubber, polystyrene, polyvinyl chloride, polymethyl methacrylate, polyphenylene oxide, polycarbonate, thermoplastic polyesters, polyurethanes, polyamides, and mixed automotive plastics recycling.

  1. Food additives and preschool children.

    PubMed

    Martyn, Danika M; McNulty, Breige A; Nugent, Anne P; Gibney, Michael J

    2013-02-01

    Food additives have been used throughout history to perform specific functions in foods. A comprehensive framework of legislation is in place within Europe to control the use of additives in the food supply and ensure they pose no risk to human health. Further to this, exposure assessments are regularly carried out to monitor population intakes and verify that intakes are not above acceptable levels (acceptable daily intakes). Young children may have a higher dietary exposure to chemicals than adults due to a combination of rapid growth rates and distinct food intake patterns. For this reason, exposure assessments are particularly important in this age group. The paper will review the use of additives and exposure assessment methods and examine factors that affect dietary exposure by young children. One of the most widely investigated unfavourable health effects associated with food additive intake in preschool-aged children are suggested adverse behavioural effects. Research that has examined this relationship has reported a variety of responses, with many noting an increase in hyperactivity as reported by parents but not when assessed using objective examiners. This review has examined the experimental approaches used in such studies and suggests that efforts are needed to standardise objective methods of measuring behaviour in preschool children. Further to this, a more holistic approach to examining food additive intakes by preschool children is advisable, where overall exposure is considered rather than focusing solely on behavioural effects and possibly examining intakes of food additives other than food colours.

  2. Extension of the standard addition method by blank addition.

    PubMed

    Steliopoulos, Panagiotis

    2015-01-01

    Standard addition involves adding varying amounts of the analyte to sample portions of fixed mass or fixed volume and submitting those portions to the sample preparation procedure. After measuring the final extract solutions, the observed signals are linearly regressed on the spiked amounts. The original unknown amount is estimated by the opposite of the abscissa intercept of the fitted straight line [1]. A limitation of this method is that only data points with abscissa values equal to and greater than zero are available so that there is no information on whether linearity holds below the spiking level zero. An approach to overcome this limitation is introduced.•Standard addition is combined with blank addition.•Blank addition means that defined mixtures of blank matrix and sample material are subjected to sample preparation to give final extract solutions.•Equations are presented to estimate the original unknown amount and to calculate the 1-2α confidence interval about this estimate using the combined data set.

  3. ADDITIVITY ASSESSMENT OF TRIHALOMETHANE MIXTURES BY PROPORTIONAL RESPONSE ADDITION

    EPA Science Inventory

    If additivity is known or assumed, the toxicity of a chemical mixture may be predicted from the dose response curves of the individual chemicals comprising the mixture. As single chemical data are abundant and mixture data sparse, mixture risk methods that utilize single chemical...

  4. Extension of the standard addition method by blank addition

    PubMed Central

    Steliopoulos, Panagiotis

    2015-01-01

    Standard addition involves adding varying amounts of the analyte to sample portions of fixed mass or fixed volume and submitting those portions to the sample preparation procedure. After measuring the final extract solutions, the observed signals are linearly regressed on the spiked amounts. The original unknown amount is estimated by the opposite of the abscissa intercept of the fitted straight line [1]. A limitation of this method is that only data points with abscissa values equal to and greater than zero are available so that there is no information on whether linearity holds below the spiking level zero. An approach to overcome this limitation is introduced.•Standard addition is combined with blank addition.•Blank addition means that defined mixtures of blank matrix and sample material are subjected to sample preparation to give final extract solutions.•Equations are presented to estimate the original unknown amount and to calculate the 1-2α confidence interval about this estimate using the combined data set. PMID:26844210

  5. [INVITED] Lasers in additive manufacturing

    NASA Astrophysics Data System (ADS)

    Pinkerton, Andrew J.

    2016-04-01

    Additive manufacturing is a topic of considerable ongoing interest, with forecasts predicting it to have major impact on industry in the future. This paper focusses on the current status and potential future development of the technology, with particular reference to the role of lasers within it. It begins by making clear the types and roles of lasers in the different categories of additive manufacturing. This is followed by concise reviews of the economic benefits and disadvantages of the technology, current state of the market and use of additive manufacturing in different industries. Details of these fields are referenced rather than expanded in detail. The paper continues, focusing on current indicators to the future of additive manufacturing. Barriers to its development, trends and opportunities in major industrial sectors, and wider opportunities for its development are covered. Evidence indicates that additive manufacturing may not become the dominant manufacturing technology in all industries, but represents an excellent opportunity for lasers to increase their influence in manufacturing as a whole.

  6. Evaluation of certain food additives.

    PubMed

    2015-01-01

    This report represents the conclusions of a Joint FAO/WHO Expert Committee convened to evaluate the safety of various food additives, including flavouring agents, and to prepare specifications for identity and purity. The first part of the report contains a general discussion of the principles governing the toxicological evaluation of and assessment of dietary exposure to food additives, including flavouring agents. A summary follows of the Committee's evaluations of technical, toxicological and dietary exposure data for eight food additives (Benzoe tonkinensis; carrageenan; citric and fatty acid esters of glycerol; gardenia yellow; lutein esters from Tagetes erecta; octenyl succinic acid-modified gum arabic; octenyl succinic acid-modified starch; paprika extract; and pectin) and eight groups of flavouring agents (aliphatic and alicyclic hydrocarbons; aliphatic and aromatic ethers; ionones and structurally related substances; miscellaneous nitrogen-containing substances; monocyclic and bicyclic secondary alcohols, ketones and related esters; phenol and phenol derivatives; phenyl-substituted aliphatic alcohols and related aldehydes and esters; and sulfur-containing heterocyclic compounds). Specifications for the following food additives were revised: citric acid; gellan gum; polyoxyethylene (20) sorbitan monostearate; potassium aluminium silicate; and Quillaia extract (Type 2). Annexed to the report are tables summarizing the Committee's recommendations for dietary exposures to and toxicological evaluations of all of the food additives and flavouring agents considered at this meeting.

  7. Clinical effects of sulphite additives.

    PubMed

    Vally, H; Misso, N L A; Madan, V

    2009-11-01

    Sulphites are widely used as preservative and antioxidant additives in the food and pharmaceutical industries. Topical, oral or parenteral exposure to sulphites has been reported to induce a range of adverse clinical effects in sensitive individuals, ranging from dermatitis, urticaria, flushing, hypotension, abdominal pain and diarrhoea to life-threatening anaphylactic and asthmatic reactions. Exposure to the sulphites arises mainly from the consumption of foods and drinks that contain these additives; however, exposure may also occur through the use of pharmaceutical products, as well as in occupational settings. While contact sensitivity to sulphite additives in topical medications is increasingly being recognized, skin reactions also occur after ingestion of or parenteral exposure to sulphites. Most studies report a 3-10% prevalence of sulphite sensitivity among asthmatic subjects following ingestion of these additives. However, the severity of these reactions varies, and steroid-dependent asthmatics, those with marked airway hyperresponsiveness, and children with chronic asthma, appear to be at greater risk. In addition to episodic and acute symptoms, sulphites may also contribute to chronic skin and respiratory symptoms. To date, the mechanisms underlying sulphite sensitivity remain unclear, although a number of potential mechanisms have been proposed. Physicians should be aware of the range of clinical manifestations of sulphite sensitivity, as well as the potential sources of exposure. Minor modifications to diet or behaviour lead to excellent clinical outcomes for sulphite-sensitive individuals.

  8. Additive Manufacturing of Hybrid Circuits

    NASA Astrophysics Data System (ADS)

    Sarobol, Pylin; Cook, Adam; Clem, Paul G.; Keicher, David; Hirschfeld, Deidre; Hall, Aaron C.; Bell, Nelson S.

    2016-07-01

    There is a rising interest in developing functional electronics using additively manufactured components. Considerations in materials selection and pathways to forming hybrid circuits and devices must demonstrate useful electronic function; must enable integration; and must complement the complex shape, low cost, high volume, and high functionality of structural but generally electronically passive additively manufactured components. This article reviews several emerging technologies being used in industry and research/development to provide integration advantages of fabricating multilayer hybrid circuits or devices. First, we review a maskless, noncontact, direct write (DW) technology that excels in the deposition of metallic colloid inks for electrical interconnects. Second, we review a complementary technology, aerosol deposition (AD), which excels in the deposition of metallic and ceramic powder as consolidated, thick conformal coatings and is additionally patternable through masking. Finally, we show examples of hybrid circuits/devices integrated beyond 2-D planes, using combinations of DW or AD processes and conventional, established processes.

  9. Postmarketing surveillance of food additives.

    PubMed

    Butchko, H H; Tschanz, C; Kotsonis, F N

    1994-08-01

    Postmarketing surveillance of consumption and of anecdotal reports of adverse health effects has been recognized by a number of regulatory authorities as a potentially useful method to provide further assurance of the safety of new food additives. Surveillance of consumption is used to estimate more reliably actual consumption levels relative to the acceptable daily intake of a food additive. Surveillance of anecdotal reports of adverse health effects is used to determine the presence of infrequent idiosyncratic responses that may not be predictable from premarket evaluations. The high-intensity sweetner, aspartame, is a food additive that has been the subject of extensive evaluation during the postmarketing period and is thus used as an example to discuss postmarketing surveillance.

  10. Additive manufacturing in production: challenges and opportunities

    NASA Astrophysics Data System (ADS)

    Ahuja, Bhrigu; Karg, Michael; Schmidt, Michael

    2015-03-01

    Additive manufacturing, characterized by its inherent layer by layer fabrication methodology has been coined by many as the latest revolution in the manufacturing industry. Due to its diversification of Materials, processes, system technology and applications, Additive Manufacturing has been synonymized with terminology such as Rapid prototyping, 3D printing, free-form fabrication, Additive Layer Manufacturing, etc. A huge media and public interest in the technology has led to an innovative attempt of exploring the technology for applications beyond the scope of the traditional engineering industry. Nevertheless, it is believed that a critical factor for the long-term success of Additive Manufacturing would be its ability to fulfill the requirements defined by the traditional manufacturing industry. A parallel development in market trends and product requirements has also lead to a wider scope of opportunities for Additive Manufacturing. The presented paper discusses some of the key challenges which are critical to ensure that Additive Manufacturing is truly accepted as a mainstream production technology in the industry. These challenges would highlight on various aspects of production such as product requirements, process management, data management, intellectual property, work flow management, quality assurance, resource planning, etc. In Addition, changing market trends such as product life cycle, mass customization, sustainability, environmental impact and localized production will form the foundation for the follow up discussion on the current limitations and the corresponding research opportunities. A discussion on ongoing research to address these challenges would include topics like process monitoring, design complexity, process standardization, multi-material and hybrid fabrication, new material development, etc.

  11. Tougher Addition Polyimides Containing Siloxane

    NASA Technical Reports Server (NTRS)

    St. Clair, T. L.; Maudgal, S.

    1986-01-01

    Laminates show increased impact resistances and other desirable mechanical properties. Bismaleamic acid extended by reaction of diaminosiloxane with maleic anhydride in 1:1 molar ratio, followed by reaction with half this molar ratio of aromatic dianhydride. Bismaleamic acid also extended by reaction of diaminosiloxane with maleic anhydride in 1:2 molar ratio, followed by reaction with half this molar ratio of aromatic diamine (Michael-addition reaction). Impact resistances improved over those of unmodified bismaleimide, showing significant increase in toughness. Aromatic addition polyimides developed as both matrix and adhesive resins for applications on future aircraft and spacecraft.

  12. Embedding Sensors During Additive Manufacturing

    SciTech Connect

    Sbriglia, Lexey Raylene

    2015-08-10

    This PowerPoint presentation had the following headings: Fused deposition modeling (FDM); Open source 3D printing; Objectives; Vibration analysis; Equipment; Design; Material choices; Failure causes, such as tension, bubbling; Potential solutions; Simulations; Embedding the sensors; LabView programming; Alternate data acquisition; Problem and proposed solution; and, Conclusions

  13. Collaborative Design

    ERIC Educational Resources Information Center

    Broderick, Debora

    2014-01-01

    This practitioner research study investigates the power of multimodal texts within a real-world context and argues that a participatory culture focused on literary arts offers marginalized high school students opportunities for collaborative design and authoring. Additionally, this article invites educators to rethink the at-risk label. This…

  14. Lubricating additive for drilling muds

    SciTech Connect

    Gutierrez, A.; Brois, S. J.; Brownawell, D. W.; Walker, T. O.

    1985-01-01

    Aqueous drilling fluids containing a minor amount of an additive composition featuring oxazolines of C/sub 1/-C/sub 30/ alkylthioglycolic acid. Such fluids are especially useful where reduced torque drilling fluids are needed. Another embodiment of this invention relates to a method of drilling utilizing the above-described fluids.

  15. Tetrasulfide extreme pressure lubricant additives

    SciTech Connect

    Gast, L.E.; Kenney, H.E.; Schwab, A.W.

    1980-08-19

    A novel class of compounds has been prepared comprising the tetrasulfides of /sup 18/C hydrocarbons, /sup 18/C fatty acids, and /sup 18/C fatty and alkyl and triglyceride esters. These tetrasulfides are useful as extreme pressure lubricant additives and show potential as replacements for sulfurized sperm whale oil.

  16. Promoting Additive Acculturation in Schools.

    ERIC Educational Resources Information Center

    Gibson, Margaret A.

    1995-01-01

    A study focusing on 113 ninth graders of Mexican descent indicates that most students and their parents adhere to a strategy of additive acculturation (incorporating skills of the new culture and language), but that the school curriculum and general school climate devalue Mexican culture. (SLD)

  17. Individualized Additional Instruction for Calculus

    ERIC Educational Resources Information Center

    Takata, Ken

    2010-01-01

    College students enrolling in the calculus sequence have a wide variance in their preparation and abilities, yet they are usually taught from the same lecture. We describe another pedagogical model of Individualized Additional Instruction (IAI) that assesses each student frequently and prescribes further instruction and homework based on the…

  18. Out of bounds additive manufacturing

    DOE PAGES

    Holshouser, Chris; Newell, Clint; Palas, Sid; Love, Lonnie J.; Kunc, Vlastimil; Lind, Randall F.; Lloyd, Peter D.; Rowe, John C.; Blue, Craig A.; Duty, Chad E.; et al

    2013-03-01

    Lockheed Martin and Oak Ridge National Laboratory are working on an additive manufacturing system capable of manufacturing components measured not in terms of inches or feet, but multiple yards in all dimensions with the potential to manufacture parts that are completely unbounded in size.

  19. Tinkertoy Color-Addition Device.

    ERIC Educational Resources Information Center

    Ferguson, Joe L.

    1995-01-01

    Describes construction and use of a simple home-built device, using an overhead projector, for use in demonstrations of the addition of various combinations of red, green, and blue light. Useful in connection with discussions of color, color vision, or color television. (JRH)

  20. Additional Financial Resources for Education.

    ERIC Educational Resources Information Center

    Hubbard, Ben C.

    This paper discusses the continuing need for additional educational funds and suggests that the only way to gain these funds is through concerted and persistent political efforts by supporters of education at both the federal and state levels. The author first points out that for many reasons declining enrollment may not decrease operating costs…

  1. Evaluation of certain food additives.

    PubMed

    2012-01-01

    This report represents the conclusions of a Joint FAO/WHO Expert Committee convened to evaluate the safety of various food additives, including flavouring agents, with a view to concluding as to safety concerns and to preparing specifications for identity and purity. The first part of the report contains a general discussion of the principles governing the toxicological evaluation of and assessment of dietary exposure to food additives, including flavouring agents. A summary follows of the Committee's evaluations of technical, toxicological and dietary exposure data for five food additives (magnesium dihydrogen diphosphate; mineral oil (medium and low viscosity) classes II and III; 3-phytase from Aspergillus niger expressed in Aspergillus niger; serine protease (chymotrypsin) from Nocardiopsis prasina expressed in Bacillus licheniformis; and serine protease (trypsin) from Fusarium oxysporum expressed in Fusarium venenatum) and 16 groups of flavouring agents (aliphatic and aromatic amines and amides; aliphatic and aromatic ethers; aliphatic hydrocarbons, alcohols, aldehydes, ketones, carboxylic acids and related esters, sulfides, disulfides and ethers containing furan substitution; aliphatic linear alpha,beta-unsaturated aldehydes, acids and related alcohols, acetals and esters; amino acids and related substances; epoxides; furfuryl alcohol and related substances; linear and branched-chain aliphatic, unsaturated, unconjugated alcohols, aldehydes, acids and related esters; miscellaneous nitrogen-containing substances; phenol and phenol derivatives; pyrazine derivatives; pyridine, pyrrole and quinoline derivatives; saturated aliphatic acyclic branched-chain primary alcohols, aldehydes and acids; simple aliphatic and aromatic sulfides and thiols; sulfur-containing heterocyclic compounds; and sulfur-substituted furan derivatives). Specifications for the following food additives were revised: ethyl cellulose, mineral oil (medium viscosity), modified starches and titanium

  2. Evaluation of certain food additives.

    PubMed

    2012-01-01

    This report represents the conclusions of a Joint FAO/WHO Expert Committee convened to evaluate the safety of various food additives, including flavouring agents, with a view to concluding as to safety concerns and to preparing specifications for identity and purity. The first part of the report contains a general discussion of the principles governing the toxicological evaluation of and assessment of dietary exposure to food additives, including flavouring agents. A summary follows of the Committee's evaluations of technical, toxicological and dietary exposure data for five food additives (magnesium dihydrogen diphosphate; mineral oil (medium and low viscosity) classes II and III; 3-phytase from Aspergillus niger expressed in Aspergillus niger; serine protease (chymotrypsin) from Nocardiopsis prasina expressed in Bacillus licheniformis; and serine protease (trypsin) from Fusarium oxysporum expressed in Fusarium venenatum) and 16 groups of flavouring agents (aliphatic and aromatic amines and amides; aliphatic and aromatic ethers; aliphatic hydrocarbons, alcohols, aldehydes, ketones, carboxylic acids and related esters, sulfides, disulfides and ethers containing furan substitution; aliphatic linear alpha,beta-unsaturated aldehydes, acids and related alcohols, acetals and esters; amino acids and related substances; epoxides; furfuryl alcohol and related substances; linear and branched-chain aliphatic, unsaturated, unconjugated alcohols, aldehydes, acids and related esters; miscellaneous nitrogen-containing substances; phenol and phenol derivatives; pyrazine derivatives; pyridine, pyrrole and quinoline derivatives; saturated aliphatic acyclic branched-chain primary alcohols, aldehydes and acids; simple aliphatic and aromatic sulfides and thiols; sulfur-containing heterocyclic compounds; and sulfur-substituted furan derivatives). Specifications for the following food additives were revised: ethyl cellulose, mineral oil (medium viscosity), modified starches and titanium

  3. An Additive Definition of Molecular Complexity.

    PubMed

    Böttcher, Thomas

    2016-03-28

    A framework for molecular complexity is established that is based on information theory and consistent with chemical knowledge. The resulting complexity index Cm is derived from abstracting the information content of a molecule by the degrees of freedom in the microenvironments on a per-atom basis, allowing the molecular complexity to be calculated in a simple and additive way. This index allows the complexity of any molecule to be universally assessed and is sensitive to stereochemistry, heteroatoms, and symmetry. The performance of this complexity index is evaluated and compared against the current state of the art. Its additive character gives consistent values also for very large molecules and supports direct comparisons of chemical reactions. Finally, this approach may provide a useful tool for medicinal chemistry in drug design and lead selection, as demonstrated by correlating molecular complexities of antibiotics with compound-specific parameters.

  4. An Additive Definition of Molecular Complexity.

    PubMed

    Böttcher, Thomas

    2016-03-28

    A framework for molecular complexity is established that is based on information theory and consistent with chemical knowledge. The resulting complexity index Cm is derived from abstracting the information content of a molecule by the degrees of freedom in the microenvironments on a per-atom basis, allowing the molecular complexity to be calculated in a simple and additive way. This index allows the complexity of any molecule to be universally assessed and is sensitive to stereochemistry, heteroatoms, and symmetry. The performance of this complexity index is evaluated and compared against the current state of the art. Its additive character gives consistent values also for very large molecules and supports direct comparisons of chemical reactions. Finally, this approach may provide a useful tool for medicinal chemistry in drug design and lead selection, as demonstrated by correlating molecular complexities of antibiotics with compound-specific parameters. PMID:26857537

  5. The teratology testing of food additives.

    PubMed

    Barrow, Paul C; Spézia, François

    2013-01-01

    The developmental and reproductive toxicity testing (including teratogenicity) of new foods and food additives is performed worldwide according to the guidelines given in the FDA Redbook. These studies are not required for substances that are generally recognized as safe, according to the FDA inventory. The anticipated cumulated human exposure level above which developmental or reproduction studies are required depends on the structure-alert category. For food additives of concern, both developmental (prenatal) and reproduction (multigeneration) studies are required. The developmental studies are performed in two species, usually the rat and the rabbit. The reproduction study is generally performed in the rat. The two rat studies are preferably combined into a single experimental design, if possible. The test methods described in the FDA Redbook are similar to those specified by the OECD for the reproductive toxicity testing of chemicals.

  6. PDII- Additional discussion of the dynamic aperture

    SciTech Connect

    Norman M. Gelfand

    2002-07-23

    This note is in the nature of an addition to the dynamic aperture calculations found in the report on the Proton Driver, FERMILAB-TM-2169. A extensive discussion of the Proton Driver lattice, as well as the nomenclature used to describe it can be found in TM-2169. Basically the proposed lattice is a racetrack design with the two arcs joined by two long straight sections. The straight sections are dispersion free. Tracking studies were undertaken with the objective of computing the dynamic aperture for the lattice and some of the results have been incorporated into TM-2169. This note is a more extensive report of those calculations.

  7. Additive effects on lubricant fuel economy

    SciTech Connect

    Kennedy, S.; Moore, L.D.

    1987-01-01

    Bench and engine tests were used to determine the effects of typical lubricating oil components on the fuel economy performance of energy conserving oils. The bench studies identified negative fuel economy effects of zinc dialkyldithiophosphates and positive effects of overbased sulfonates. The Sequence VI dynamometer test quantified viscometric influences on fuel economy; results indicated that SAE 5W-30 oils are not always more fuel efficient than 10W-30 analogs, and that viscosity index improver type has a large impact on fuel economy. These effects were integrated with additive effects on other formulation criteria to design an overall system.

  8. Additive Manufacturing for Affordable Rocket Engines

    NASA Technical Reports Server (NTRS)

    West, Brian; Robertson, Elizabeth; Osborne, Robin; Calvert, Marty

    2016-01-01

    Additive manufacturing (also known as 3D printing) technology has the potential to drastically reduce costs and lead times associated with the development of complex liquid rocket engine systems. NASA is using 3D printing to manufacture rocket engine components including augmented spark igniters, injectors, turbopumps, and valves. NASA is advancing the process to certify these components for flight. Success Story: MSFC has been developing rocket 3D-printing technology using the Selective Laser Melting (SLM) process. Over the last several years, NASA has built and tested several injectors and combustion chambers. Recently, MSFC has 3D printed an augmented spark igniter for potential use the RS-25 engines that will be used on the Space Launch System. The new design is expected to reduce the cost of the igniter by a factor of four. MSFC has also 3D printed and tested a liquid hydrogen turbopump for potential use on an Upper Stage Engine. Additive manufacturing of the turbopump resulted in a 45% part count reduction. To understanding how the 3D printed parts perform and to certify them for flight, MSFC built a breadboard liquid rocket engine using additive manufactured components including injectors, turbomachinery, and valves. The liquid rocket engine was tested seven times in 2016 using liquid oxygen and liquid hydrogen. In addition to exposing the hardware to harsh environments, engineers learned to design for the new manufacturing technique, taking advantage of its capabilities and gaining awareness of its limitations. Benefit: The 3D-printing technology promises reduced cost and schedule for rocket engines. Cost is a function of complexity, and the most complicated features provide the largest opportunities for cost reductions. This is especially true where brazes or welds can be eliminated. The drastic reduction in part count achievable with 3D printing creates a waterfall effect that reduces the number of processes and drawings, decreases the amount of touch

  9. Decontamination formulation with sorbent additive

    DOEpatents

    Tucker; Mark D. , Comstock; Robert H.

    2007-10-16

    A decontamination formulation and method of making that neutralizes the adverse health effects of both chemical and biological compounds, especially chemical warfare (CW) and biological warfare (BW) agents, and toxic industrial chemicals. The formulation provides solubilizing compounds that serve to effectively render the chemical and biological compounds, particularly CW and BW compounds, susceptible to attack, and at least one reactive compound that serves to attack (and detoxify or kill) the compound. The formulation includes at least one solubilizing agent, a reactive compound, a bleaching activator, a sorbent additive, and water. The highly adsorbent, water-soluble sorbent additive (e.g., sorbitol or mannitol) is used to "dry out" one or more liquid ingredients, such as the liquid bleaching activator (e.g., propylene glycol diacetate or glycerol diacetate) and convert the activator into a dry, free-flowing powder that has an extended shelf life, and is more convenient to handle and mix in the field.

  10. Additive-free digital microfluidics.

    PubMed

    Freire, Sergio L S; Tanner, Brendan

    2013-07-16

    Digital microfluidics, a technique for manipulation of droplets, is becoming increasingly important for the development of miniaturized platforms for laboratory processes. Despite the enthusiasm, droplet motion is frequently hindered by the desorption of proteins or other analytes to surfaces. Current approaches to minimize this unwanted surface fouling involve the addition of extra species to the droplet or its surroundings, which might be problematic depending on the droplet content. Here, a new strategy is introduced to move droplets containing cells and other analytes on solid substrates, without extra moieties; in particular, droplets with bovine serum albumin could be moved at a concentration 2000 times higher than previously reported (without additives). This capability is achieved by using a soot-based superamphiphobic surface combined with a new device geometry, which favors droplet rolling. Contrasting with electrowetting, wetting forces are not required for droplet motion.

  11. Additive concentrates for distillate fuels

    SciTech Connect

    Rossi, A.; Lewtas, K.

    1985-08-27

    An additive concentrate for incorporation into wax containing petroleum fuel oil compositions to improve low temperature flow properties comprising an oil solution containing: 3% to 90 wt. % of a C30-C300 oil-soluble nitrogen compound wax crystal growth inhibitor having at least one straight C8-C40 alkyl chain and partial esters, and at least one mole per mole of an organic acid capable of hydrogen bonding to improve the solubility in the oil.

  12. Additive manufacturing of hybrid circuits

    DOE PAGES

    Bell, Nelson S.; Sarobol, Pylin; Cook, Adam; Clem, Paul G.; Keicher, David M.; Hirschfeld, Deidre; Hall, Aaron Christopher

    2016-03-26

    There is a rising interest in developing functional electronics using additively manufactured components. Considerations in materials selection and pathways to forming hybrid circuits and devices must demonstrate useful electronic function; must enable integration; and must complement the complex shape, low cost, high volume, and high functionality of structural but generally electronically passive additively manufactured components. This article reviews several emerging technologies being used in industry and research/development to provide integration advantages of fabricating multilayer hybrid circuits or devices. First, we review a maskless, noncontact, direct write (DW) technology that excels in the deposition of metallic colloid inks for electrical interconnects.more » Second, we review a complementary technology, aerosol deposition (AD), which excels in the deposition of metallic and ceramic powder as consolidated, thick conformal coatings and is additionally patternable through masking. As a result, we show examples of hybrid circuits/devices integrated beyond 2-D planes, using combinations of DW or AD processes and conventional, established processes.« less

  13. Evaluation of certain food additives.

    PubMed

    2009-01-01

    This report represents the conclusions of a Joint FAO/WHO Expert Committee convened to evaluate the safety of various food additives, including flavouring agents, with a view to recommending acceptable daily intakes (ADIs) and to preparing specifications for identity and purity. The first part of the report contains a general discussion of the principles governing the toxicological evaluation and assessment of intake of food additives (in particular, flavouring agents). A summary follows of the Committee's evaluations of technical, toxicological and intake data for certain food additives (asparaginase from Aspergillus niger expressed in A. niger, calcium lignosulfonate (40-65), ethyl lauroyl arginate, paprika extract, phospholipase C expressed in Pichia pastoris, phytosterols, phytostanols and their esters, polydimethylsiloxane, steviol glycosides and sulfites [assessment of dietary exposure]) and 10 groups of related flavouring agents (aliphatic branched-chain saturated and unsaturated alcohols, aldehydes, acids and related esters; aliphatic linear alpha,beta-unsaturated aldehydes, acids and related alcohols, acetals and esters; aliphatic secondary alcohols, ketones and related esters; alkoxy-substituted allylbenzenes present in foods and essential oils and used as flavouring agents; esters of aliphatic acyclic primary alcohols with aliphatic linear saturated carboxylic acids; furan-substituted aliphatic hydrocarbons, alcohols, aldehydes, ketones, carboxylic acids and related esters, sulfides, disulfides and ethers; miscellaneous nitrogen-containing substances; monocyclic and bicyclic secondary alcohols, ketones and related esters; hydroxy- and alkoxy-substituted benzyl derivatives; and substances structurally related to menthol). Specifications for the following food additives were revised: canthaxanthin; carob bean gum and carob bean gum (clarified); chlorophyllin copper complexes, sodium and potassium salts; Fast Green FCF; guar gum and guar gum (clarified

  14. Fire-Retardant Polymeric Additives

    NASA Technical Reports Server (NTRS)

    Williams, Martha K.; Smith, Trent M.

    2011-01-01

    Polyhydroxyamide (PHA) and polymethoxyamide (PMeOA) are fire-retardant (FR) thermoplastic polymers and have been found to be useful as an additive for imparting fire retardant properties to other compatible, thermoplastic polymers (including some elastomers). Examples of compatible flammable polymers include nylons, polyesters, and acrylics. Unlike most prior additives, PHA and PMeOA do not appreciably degrade the mechanical properties of the matrix polymer; indeed, in some cases, mechanical properties are enhanced. Also, unlike some prior additives, PHA and PMeOA do not decompose into large amounts of corrosive or toxic compounds during combustion and can be processed at elevated temperatures. PMeOA derivative formulations were synthesized and used as an FR additive in the fabrication of polyamide (PA) and polystyrene (PS) composites with notable reduction (>30 percent for PS) in peak heat release rates compared to the neat polymer as measured by a Cone Calorimeter (ASTM E1354). Synergistic effects were noted with nanosilica composites. These nanosilica composites had more than 50-percent reduction in peak heat release rates. In a typical application, a flammable thermoplastic, thermoplastic blend, or elastomer that one seeks to render flame-retardant is first dry-mixed with PHA or PMeOA or derivative thereof. The proportion of PHA or PMeOA or derivative in the mixture is typically chosen to lie between 1 and 20 weight percent. The dry blend can then be melt-extruded. The extruded polymer blend can further be extruded and/or molded into fibers, pipes, or any other of a variety of objects that may be required to be fire-retardant. The physical and chemical mechanisms which impart flame retardancy of the additive include inhibiting free-radical oxidation in the vapor phase, preventing vaporization of fuel (the polymer), and cooling through the formation of chemical bonds in either the vapor or the condensed phase. Under thermal stress, the cyclic hydroxyl/ methoxy

  15. Metal Additive Manufacturing: A Review

    NASA Astrophysics Data System (ADS)

    Frazier, William E.

    2014-06-01

    This paper reviews the state-of-the-art of an important, rapidly emerging, manufacturing technology that is alternatively called additive manufacturing (AM), direct digital manufacturing, free form fabrication, or 3D printing, etc. A broad contextual overview of metallic AM is provided. AM has the potential to revolutionize the global parts manufacturing and logistics landscape. It enables distributed manufacturing and the productions of parts-on-demand while offering the potential to reduce cost, energy consumption, and carbon footprint. This paper explores the material science, processes, and business consideration associated with achieving these performance gains. It is concluded that a paradigm shift is required in order to fully exploit AM potential.

  16. Individualized additional instruction for calculus

    NASA Astrophysics Data System (ADS)

    Takata, Ken

    2010-10-01

    College students enrolling in the calculus sequence have a wide variance in their preparation and abilities, yet they are usually taught from the same lecture. We describe another pedagogical model of Individualized Additional Instruction (IAI) that assesses each student frequently and prescribes further instruction and homework based on the student's performance. Our study compares two calculus classes, one taught with mandatory remedial IAI and the other without. The class with mandatory remedial IAI did significantly better on comprehensive multiple-choice exams, participated more frequently in classroom discussion and showed greater interest in theorem-proving and other advanced topics.

  17. The Mozart Effect: Additional Data.

    PubMed

    Hughes, John R.

    2002-04-01

    After the review of the Mozart effect was published in this journal (Hughes JR. Epilepsy Behav 2001;2:369-417), additional data from the music of Haydn and Liszt have been analyzed that may account for the decrease in seizure activity originally reported during Mozart music. Even with these added data Mozart music continued to score significantly higher than the selections from the other six composers in one of the important characteristics of this music, namely, the repetition of the melody. However Haydn's values were second highest among Mozart, J. S. Bach, Wagner, Beethoven, Chopin, and Liszt.

  18. New ESP additive controls particulates

    SciTech Connect

    Durham, M.D.; Baldrey, K.E.; Bustard, C.J.; Martin, C.E.; Dharmarajan, N.N.

    1997-06-01

    This article reports that a conditioning agent enhanced precipitator performance after plant switched to low-sulfur coal. Firing low-sulfur coal at a power plant designed for medium- or high-sulfur coal will impact the downstream particulate control device. Since the performance of an electro-static precipitator (ESP) is a strong function of the sulfur content in the coal, switching to a low-sulfur coal will severely impact collection efficiency. Particle resistivity is the dominant parameter affecting the performance of an ESP. When the resistivity is too high, the ESP must be increased in size by a factor of two to three, resulting in proportionally increased capital and operating costs. Fly ash from low-sulfur coal is known to have a typical resistivity one or two orders of magnitude above that for ideal collection efficiency in a well-designed ESP. Therefore, when a utility burning a medium- or high-sulfur coal switches to a low-sulfur coal, the increase in particle resistivity resulting from the reduced SO{sub 3} concentration will lead to severe problems in the ESP. There have been many instances where utilities have switched from a high- to a low-sulfur coal, and the problems caused by the increased resistivity have had such a devastating effect on the performance of the ESP that emissions have increased by a factor of 10.

  19. Additive manufacturing of RF absorbers

    NASA Astrophysics Data System (ADS)

    Mills, Matthew S.

    The ability of additive manufacturing techniques to fabricate integrated electromagnetic absorbers tuned for specific radio frequency bands within structural composites allows for unique combinations of mechanical and electromagnetic properties. These composites and films can be used for RF shielding of sensitive electromagnetic components through in-plane and out-of-plane RF absorption. Structural composites are a common building block of many commercial platforms. These platforms may be placed in situations in which there is a need for embedded RF absorbing properties along with structural properties. Instead of adding radar absorbing treatments to the external surface of existing structures, which adds increased size, weight and cost; it could prove to be advantageous to integrate the microwave absorbing properties directly into the composite during the fabrication process. In this thesis, a method based on additive manufacturing techniques of composites structures with prescribed electromagnetic loss, within the frequency range 1 to 26GHz, is presented. This method utilizes screen printing and nScrypt micro dispensing to pattern a carbon based ink onto low loss substrates. The materials chosen for this study will be presented, and the fabrication technique that these materials went through to create RF absorbing structures will be described. The calibration methods used, the modeling of the RF structures, and the applications in which this technology can be utilized will also be presented.

  20. Fuel Additives: Canada bans MMT

    SciTech Connect

    Sissell, K.

    1997-04-16

    The Canadian Senate voted late last week to ban use of the manganese-based fuel additive MMT, produced only in the US by Ethyl. MMT, which has been sold in Canada for the past 20 years and accounts for about half of Ethyl`s Canadian sales, has been criticized by environmentalists, who have raised public health concerns, and automakers, who say it harms emission control systems. {open_quotes}Canada`s vote is a great victory for public health and the environment,{close_quotes} says Environmental Defense Fund executive director Fred Krupp. {open_quotes}The US should move swiftly to follow suit and suspend sales of MMT until adequate toxicity testing on the additive is completed.{close_quotes} EPA had refused to approve MMT for sale because of health concerns but was compelled to do so by a December 1995 court ruling. Ethyl asserts the ban violates Canada`s obligations under Nafta and says it will file a damage claim with the Nafta arbitration panel.

  1. Structure Property Studies for Additively Manufactured Parts

    SciTech Connect

    Milenski, Helen M; Schmalzer, Andrew Michael; Kelly, Daniel

    2015-08-17

    Since the invention of modern Additive Manufacturing (AM) processes engineers and designers have worked hard to capitalize on the unique building capabilities that AM allows. By being able to customize the interior fill of parts it is now possible to design components with a controlled density and customized internal structure. The creation of new polymers and polymer composites allow for even greater control over the mechanical properties of AM parts. One of the key reasons to explore AM, is to bring about a new paradigm in part design, where materials can be strategically optimized in a way that conventional subtractive methods cannot achieve. The two processes investigated in my research were the Fused Deposition Modeling (FDM) process and the Direct Ink Write (DIW) process. The objectives of the research were to determine the impact of in-fill density and morphology on the mechanical properties of FDM parts, and to determine if DIW printed samples could be produced where the filament diameter was varied while the overall density remained constant.

  2. Using Set Model for Learning Addition of Integers

    ERIC Educational Resources Information Center

    Lestari, Umi Puji; Putri, Ratu Ilma Indra; Hartono, Yusuf

    2015-01-01

    This study aims to investigate how set model can help students' understanding of addition of integers in fourth grade. The study has been carried out to 23 students and a teacher of IVC SD Iba Palembang in January 2015. This study is a design research that also promotes PMRI as the underlying design context and activity. Results showed that the…

  3. High School Science Technology Additions, Midland Public Schools.

    ERIC Educational Resources Information Center

    Design Cost Data, 2001

    2001-01-01

    Discusses design goals, space requirements, and need for mobile furniture and "imagination stations" at Michigan's Midland Public High School science technology addition. Describes the architectural design, costs, and specifications. Includes floor plans, general description, photos and a list of consultants, manufacturers, and suppliers used for…

  4. SIPSEY WILDERNESS AND ADDITIONS, ALABAMA.

    USGS Publications Warehouse

    Schweinfurth, Stanley P.; Mory, Peter C.

    1984-01-01

    On the basis of geologic, geochemical, and mineral surveys the Sipsey Wilderness and additions are deemed to have little promise for the occurrence of metallic mineral resources. Although limestone, shale, and sandstone resources that occur in the area are physically suitable for a variety of uses, similar materials are available outside the area closer to transportation routes and potential markets. A small amount of coal has been identified in the area, occurring as nonpersistent beds less than 28 in. thick. Oil and (or) natural gas resources may be present if suitable structural traps exist in the subsurface. Therefore, the area has a probable oil and gas potential. Small amounts of asphaltic sandstone and limestone, commonly referred to as tar sands, may also occur in the subsurface. 5 refs.

  5. A novel addition polyimide adhesive

    NASA Technical Reports Server (NTRS)

    St.clair, T. L.; Progar, D. J.

    1981-01-01

    An addition polyimide adhesive, LARC 13, was developed which shows promise for bonding both titanium and composites for applications which require service temperatures in excess of 533 K. The LARC 13 is based on an oligomeric bis nadimide containing a meta linked aromatic diamine. The adhesive melts prior to polymerization due to its oligomeric nature, thereby allowing it to be processed at 344 kPa or less. Therefore, LARC 13 is ideal for the bonding of honeycomb sandwich structures. After melting, the resin thermosets during the cure of the nadic endcaps to a highly crosslinked system. Few volatiles are evolved, thus allowing large enclosed structures to be bonded. Preparation of the adhesive as well as bonding, aging, and testing of lap shear and honeycomb samples are discussed.

  6. Diesel fuel detergent additive performance and assessment

    SciTech Connect

    Vincent, M.W.; Papachristos, M.J.; Williams, D.; Burton, J.

    1994-10-01

    Diesel fuel detergent additives are increasingly linked with high quality automotive diesel fuels. Both in Europe and in the USA, field problems associated with fuel injector coking or fouling have been experienced. In Europe indirect injection (IDI) light duty engines used in passenger cars were affected, while in the USA, a direct injection (DI) engine in heavy duty truck applications experienced field problems. In both cases, a fuel additive detergent performance test has evolved using an engine linked with the original field problem, although engine design modifications employed by the manufacturers have ensured improved operation in service. Increasing awareness of the potential for injector nozzle coking to cause deterioration in engine performance is coupled with a need to meet ever more stringent exhaust emissions legislation. These two requirements indicate that the use of detergency additives will continue to be associated with high quality diesel fuels. The paper examines detergency performance evaluated in a range of IDI and DI engines and correlates performance in the two most widely recognised test engines, namely the Peugeot 1.9 litre IDI, and Cummins L10 DI engines. 17 refs., 18 figs., 5 tabs.

  7. Adverse reactions to food additives.

    PubMed

    Simon, R A

    1986-01-01

    There are thousands of agents that are intentionally added to the food that we consume. These include preservatives, stabilizers, conditioners, thickeners, colorings, flavorings, sweeteners, antioxidants, etc. etc. Yet only a surprisingly small number have been associated with hypersensitivity reactions. Amongst all the additives, FD&C dyes have been most frequently associated with adverse reactions. Tartrazine is the most notorious of them all; however, critical review of the medical literature and current Scripps Clinic studies would indicate that tartrazine has been confirmed to be at best only occasionally associated with flares of urticaria or asthma. There is no convincing evidence in the literature of reactivity to the other azo or nonazo dyes. This can also be said of BHA/BHT, nitrites/nitrates and sorbates. Parabens have been shown to elicit IgE mediated hypersensitivity reactions when used as pharmaceutical preservatives; however, as with the other additives noted above, ingested parabens have only occasionally been associated with adverse reactions. MSG, the cause of the 'Chinese restaurant syndrome' has only been linked to asthma in one report. Sulfiting agents used primarily as food fresheners and to control microbial growth in fermented beverages have been established as the cause of any where from mild to severe and even fatal reactions in at least 5% of the asthmatic population. Other reactions reported to follow sulfite ingestion include anaphylaxis, gastro intestinal complaints and dermatological eruptions. The prevalence of these non asthmatic reactions is unknown. The mechanism of sulfite sensitive asthma is also unknown but most likely involves hyperreactivity to inhale SO2 in the great majority of cases; however, there are reports of IgE mediated reactions and other sulfite sensitive asthmatics have been found with low levels of sulfite oxidase; necessary to oxidize endogenous sulfite to sulfate.

  8. 48 CFR 22.406-3 - Additional classifications.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Involving Construction 22.406-3 Additional classifications. (a) If any laborer or mechanic is to be employed... mechanics to be employed in the additional classification (if known) or their representatives agree to the... any amount designated for fringe benefits); or (2) If the contractor, the laborers or mechanics to...

  9. 7 CFR 3201.103 - Gasoline fuel additives.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 15 2014-01-01 2014-01-01 false Gasoline fuel additives. 3201.103 Section 3201.103... Designated Items § 3201.103 Gasoline fuel additives. (a) Definition. Chemical agents added to gasoline to increase octane levels, improve lubricity, and provide engine cleaning properties to gasoline-fired...

  10. Application of Additively Manufactured Components in Rocket Engine Turbopumps

    NASA Technical Reports Server (NTRS)

    Calvert, Marty, Jr.; Hanks, Andrew; Schmauch, Preston; Delessio, Steve

    2015-01-01

    The use of additive manufacturing technology has the potential to revolutionize the development of turbopump components in liquid rocket engines. When designing turbomachinery with the additive process there are several benefits and risks that are leveraged relative to a traditional development cycle. This topic explores the details and development of a 90,000 RPM Liquid Hydrogen Turbopump from which 90% of the parts were derived from the additive process. This turbopump was designed, developed and will be tested later this year at Marshall Space Flight Center.

  11. Additive attacks on speaker recognition

    NASA Astrophysics Data System (ADS)

    Farrokh Baroughi, Alireza; Craver, Scott

    2014-02-01

    Speaker recognition is used to identify a speaker's voice from among a group of known speakers. A common method of speaker recognition is a classification based on cepstral coefficients of the speaker's voice, using a Gaussian mixture model (GMM) to model each speaker. In this paper we try to fool a speaker recognition system using additive noise such that an intruder is recognized as a target user. Our attack uses a mixture selected from a target user's GMM model, inverting the cepstral transformation to produce noise samples. In our 5 speaker data base, we achieve an attack success rate of 50% with a noise signal at 10dB SNR, and 95% by increasing noise power to 0dB SNR. The importance of this attack is its simplicity and flexibility: it can be employed in real time with no processing of an attacker's voice, and little computation is needed at the moment of detection, allowing the attack to be performed by a small portable device. For any target user, knowing that user's model or voice sample is sufficient to compute the attack signal, and it is enough that the intruder plays it while he/she is uttering to be classiffed as the victim.

  12. Additive Transforms Paint into Insulation

    NASA Technical Reports Server (NTRS)

    2007-01-01

    Tech Traders Inc. sought assistance developing low-cost, highly effective coatings and paints that created useful thermal reflectance and were safe and non-toxic. In cooperation with a group of engineers at Kennedy Space Center., Tech Traders created Insuladd, a powder additive made up of microscopic, inert gas-filled, ceramic microspheres that can be mixed into ordinary interior or exterior paint, allowing the paint to act like a layer of insulation. When the paint dries, this forms a radiant heat barrier, turning the ordinary house paint into heat-reflecting thermal paint. According to Tech Traders, the product works with all types of paints and coatings and will not change the coverage rate, application, or adhesion of the paint. Other useful applications include feed storage silos to help prevent feed spoilage, poultry hatcheries to reduce the summer heat and winter cold effects, and on military vehicles and ships. Tech Traders has continued its connection to the aerospace community by recently providing Lockheed Martin Corporation with one of its thermal products for use on the F-22 Raptor.

  13. Sustainability Characterization for Additive Manufacturing

    PubMed Central

    Mani, Mahesh; Lyons, Kevin W; Gupta, SK

    2014-01-01

    Additive manufacturing (AM) has the potential to create geometrically complex parts that require a high degree of customization, using less material and producing less waste. Recent studies have shown that AM can be an economically viable option for use by the industry, yet there are some inherent challenges associated with AM for wider acceptance. The lack of standards in AM impedes its use for parts production since industries primarily depend on established standards in processes and material selection to ensure the consistency and quality. Inability to compare AM performance against traditional manufacturing methods can be a barrier for implementing AM processes. AM process sustainability has become a driver due to growing environmental concerns for manufacturing. This has reinforced the importance to understand and characterize AM processes for sustainability. Process characterization for sustainability will help close the gaps for comparing AM performance to traditional manufacturing methods. Based on a literature review, this paper first examines the potential environmental impacts of AM. A methodology for sustainability characterization of AM is then proposed to serve as a resource for the community to benchmark AM processes for sustainability. Next, research perspectives are discussed along with relevant standardization efforts. PMID:26601038

  14. Additively manufactured porous tantalum implants.

    PubMed

    Wauthle, Ruben; van der Stok, Johan; Amin Yavari, Saber; Van Humbeeck, Jan; Kruth, Jean-Pierre; Zadpoor, Amir Abbas; Weinans, Harrie; Mulier, Michiel; Schrooten, Jan

    2015-03-01

    The medical device industry's interest in open porous, metallic biomaterials has increased in response to additive manufacturing techniques enabling the production of complex shapes that cannot be produced with conventional techniques. Tantalum is an important metal for medical devices because of its good biocompatibility. In this study selective laser melting technology was used for the first time to manufacture highly porous pure tantalum implants with fully interconnected open pores. The architecture of the porous structure in combination with the material properties of tantalum result in mechanical properties close to those of human bone and allow for bone ingrowth. The bone regeneration performance of the porous tantalum was evaluated in vivo using an orthotopic load-bearing bone defect model in the rat femur. After 12 weeks, substantial bone ingrowth, good quality of the regenerated bone and a strong, functional implant-bone interface connection were observed. Compared to identical porous Ti-6Al-4V structures, laser-melted tantalum shows excellent osteoconductive properties, has a higher normalized fatigue strength and allows for more plastic deformation due to its high ductility. It is therefore concluded that this is a first step towards a new generation of open porous tantalum implants manufactured using selective laser melting.

  15. Additively manufactured porous tantalum implants.

    PubMed

    Wauthle, Ruben; van der Stok, Johan; Amin Yavari, Saber; Van Humbeeck, Jan; Kruth, Jean-Pierre; Zadpoor, Amir Abbas; Weinans, Harrie; Mulier, Michiel; Schrooten, Jan

    2015-03-01

    The medical device industry's interest in open porous, metallic biomaterials has increased in response to additive manufacturing techniques enabling the production of complex shapes that cannot be produced with conventional techniques. Tantalum is an important metal for medical devices because of its good biocompatibility. In this study selective laser melting technology was used for the first time to manufacture highly porous pure tantalum implants with fully interconnected open pores. The architecture of the porous structure in combination with the material properties of tantalum result in mechanical properties close to those of human bone and allow for bone ingrowth. The bone regeneration performance of the porous tantalum was evaluated in vivo using an orthotopic load-bearing bone defect model in the rat femur. After 12 weeks, substantial bone ingrowth, good quality of the regenerated bone and a strong, functional implant-bone interface connection were observed. Compared to identical porous Ti-6Al-4V structures, laser-melted tantalum shows excellent osteoconductive properties, has a higher normalized fatigue strength and allows for more plastic deformation due to its high ductility. It is therefore concluded that this is a first step towards a new generation of open porous tantalum implants manufactured using selective laser melting. PMID:25500631

  16. Sustainability Characterization for Additive Manufacturing.

    PubMed

    Mani, Mahesh; Lyons, Kevin W; Gupta, S K

    2014-01-01

    Additive manufacturing (AM) has the potential to create geometrically complex parts that require a high degree of customization, using less material and producing less waste. Recent studies have shown that AM can be an economically viable option for use by the industry, yet there are some inherent challenges associated with AM for wider acceptance. The lack of standards in AM impedes its use for parts production since industries primarily depend on established standards in processes and material selection to ensure the consistency and quality. Inability to compare AM performance against traditional manufacturing methods can be a barrier for implementing AM processes. AM process sustainability has become a driver due to growing environmental concerns for manufacturing. This has reinforced the importance to understand and characterize AM processes for sustainability. Process characterization for sustainability will help close the gaps for comparing AM performance to traditional manufacturing methods. Based on a literature review, this paper first examines the potential environmental impacts of AM. A methodology for sustainability characterization of AM is then proposed to serve as a resource for the community to benchmark AM processes for sustainability. Next, research perspectives are discussed along with relevant standardization efforts.

  17. Additive manufacturing of biologically-inspired materials.

    PubMed

    Studart, André R

    2016-01-21

    Additive manufacturing (AM) technologies offer an attractive pathway towards the fabrication of functional materials featuring complex heterogeneous architectures inspired by biological systems. In this paper, recent research on the use of AM approaches to program the local chemical composition, structure and properties of biologically-inspired materials is reviewed. A variety of structural motifs found in biological composites have been successfully emulated in synthetic systems using inkjet-based, direct-writing, stereolithography and slip casting technologies. The replication in synthetic systems of design principles underlying such structural motifs has enabled the fabrication of lightweight cellular materials, strong and tough composites, soft robots and autonomously shaping structures with unprecedented properties and functionalities. Pushing the current limits of AM technologies in future research should bring us closer to the manufacturing capabilities of living organisms, opening the way for the digital fabrication of advanced materials with superior performance, lower environmental impact and new functionalities.

  18. Additive manufacturing: Overview and NDE challenges

    NASA Astrophysics Data System (ADS)

    Slotwinski, J. A.

    2014-02-01

    Additive manufacturing (AM) processes are capable of producing highly complex and customized parts, without the need for dedicated tooling, and can produce parts directly from the part design information. These types of processes are poised to revolutionize the manufacturing industry, yet there are several challenges that are currently preventing more widespread adoption of AM technologies. Traditional Non-Destructive Evaluation (NDE) methods could be utilized in both in-process and post-process applications to help overcome these challenges, although currently there are very few examples of in-situ sensors for monitoring AM processes. This paper gives an overview of AM technology, and discusses the potential benefits and challenges of using NDE in AM applications.

  19. Additive Manufacturing: Making Imagination the Major Limitation

    NASA Astrophysics Data System (ADS)

    Zhai, Yuwei; Lados, Diana A.; LaGoy, Jane L.

    2014-05-01

    Additive manufacturing (AM) refers to an advanced technology used for the fabrication of three-dimensional near-net-shaped functional components directly from computer models, using unit materials. The fundamentals and working principle of AM offer several advantages, including near-net-shape capabilities, superior design and geometrical flexibility, innovative multi-material fabrication, reduced tooling and fixturing, shorter cycle time for design and manufacturing, instant local production at a global scale, and material, energy, and cost efficiency. Well suiting the requests of modern manufacturing climate, AM is viewed as the new industrial revolution, making its way into a continuously increasing number of industries, such as aerospace, defense, automotive, medical, architecture, art, jewelry, and food. This overview was created to relate the historical evolution of the AM technology to its state-of-the-art developments and emerging applications. Generic thoughts on the microstructural characteristics, properties, and performance of AM-fabricated materials will also be discussed, primarily related to metallic materials. This write-up will introduce the general reader to specifics of the AM field vis-à-vis advantages and common techniques, materials and properties, current applications, and future opportunities.

  20. Additive manufacturing of tools for lapping glass

    NASA Astrophysics Data System (ADS)

    Williams, Wesley B.

    2013-09-01

    Additive manufacturing technologies have the ability to directly produce parts with complex geometries without the need for secondary processes, tooling or fixtures. This ability was used to produce concave lapping tools with a VFlash 3D printer from 3D Systems. The lapping tools were first designed in Creo Parametric with a defined constant radius and radial groove pattern. The models were converted to stereolithography files which the VFlash used in building the parts, layer by layer, from a UV curable resin. The tools were rotated at 60 rpm and used with 120 grit and 220 grit silicon carbide lapping paste to lap 0.750" diameter fused silica workpieces. The samples developed a matte appearance on the lapped surface that started as a ring at the edge of the workpiece and expanded to the center. This indicated that as material was removed, the workpiece radius was beginning to match the tool radius. The workpieces were then cleaned and lapped on a second tool (with equivalent geometry) using a 3000 grit corundum aluminum oxide lapping paste, until a near specular surface was achieved. By using lapping tools that have been additively manufactured, fused silica workpieces can be lapped to approach a specified convex geometry. This approach may enable more rapid lapping of near net shape workpieces that minimize the material removal required by subsequent polishing. This research may also enable development of new lapping tool geometry and groove patterns for improved loose abrasive finishing.

  1. Additive manufacturing of glass for optical applications

    NASA Astrophysics Data System (ADS)

    Luo, Junjie; Gilbert, Luke J.; Bristow, Douglas A.; Landers, Robert G.; Goldstein, Jonathan T.; Urbas, Augustine M.; Kinzel, Edward C.

    2016-04-01

    Glasses including fused quartz have significant scientific and engineering applications including optics, communications, electronics, and hermetic seals. This paper investigates a filament fed process for Additive Manufacturing (AM) of fused quartz. Additive manufacturing has several potential benefits including increased design freedom, faster prototyping, and lower processing costs for small production volumes. However, current research in AM of glasses is limited and has focused on non-optical applications. Fused quartz is studied here because of its desirability for high-quality optics due to its high transmissivity and thermal stability. Fused quartz also has a higher working temperature than soda lime glass which poses a challenge for AM. In this work, fused quartz filaments are fed into a CO2 laser generated melt pool, smoothly depositing material onto the work piece. Single tracks are printed to explore the effects that different process parameters have on the morphology of printed fused quartz. A spectrometer is used to measure the thermal radiation incandescently emitted from the melt pool. Thin-walls are printed to study the effects of layer-to-layer height. Finally, a 3D fused quartz cube is printed using the newly acquired layer height and polished on each surface. The transmittance and index homogeneity of the polished cube are both measured. These results show that the filament fed process has the potential to print fused quartz with optical transparency and of index of refraction uniformity approaching bulk processed glass.

  2. Mechanical properties of additively manufactured octagonal honeycombs.

    PubMed

    Hedayati, R; Sadighi, M; Mohammadi-Aghdam, M; Zadpoor, A A

    2016-12-01

    Honeycomb structures have found numerous applications as structural and biomedical materials due to their favourable properties such as low weight, high stiffness, and porosity. Application of additive manufacturing and 3D printing techniques allows for manufacturing of honeycombs with arbitrary shape and wall thickness, opening the way for optimizing the mechanical and physical properties for specific applications. In this study, the mechanical properties of honeycomb structures with a new geometry, called octagonal honeycomb, were investigated using analytical, numerical, and experimental approaches. An additive manufacturing technique, namely fused deposition modelling, was used to fabricate the honeycomb from polylactic acid (PLA). The honeycombs structures were then mechanically tested under compression and the mechanical properties of the structures were determined. In addition, the Euler-Bernoulli and Timoshenko beam theories were used for deriving analytical relationships for elastic modulus, yield stress, Poisson's ratio, and buckling stress of this new design of honeycomb structures. Finite element models were also created to analyse the mechanical behaviour of the honeycombs computationally. The analytical solutions obtained using Timoshenko beam theory were close to computational results in terms of elastic modulus, Poisson's ratio and yield stress, especially for relative densities smaller than 25%. The analytical solutions based on the Timoshenko analytical solution and the computational results were in good agreement with experimental observations. Finally, the elastic properties of the proposed honeycomb structure were compared to those of other honeycomb structures such as square, triangular, hexagonal, mixed, diamond, and Kagome. The octagonal honeycomb showed yield stress and elastic modulus values very close to those of regular hexagonal honeycombs and lower than the other considered honeycombs. PMID:27612831

  3. Mechanical properties of additively manufactured octagonal honeycombs.

    PubMed

    Hedayati, R; Sadighi, M; Mohammadi-Aghdam, M; Zadpoor, A A

    2016-12-01

    Honeycomb structures have found numerous applications as structural and biomedical materials due to their favourable properties such as low weight, high stiffness, and porosity. Application of additive manufacturing and 3D printing techniques allows for manufacturing of honeycombs with arbitrary shape and wall thickness, opening the way for optimizing the mechanical and physical properties for specific applications. In this study, the mechanical properties of honeycomb structures with a new geometry, called octagonal honeycomb, were investigated using analytical, numerical, and experimental approaches. An additive manufacturing technique, namely fused deposition modelling, was used to fabricate the honeycomb from polylactic acid (PLA). The honeycombs structures were then mechanically tested under compression and the mechanical properties of the structures were determined. In addition, the Euler-Bernoulli and Timoshenko beam theories were used for deriving analytical relationships for elastic modulus, yield stress, Poisson's ratio, and buckling stress of this new design of honeycomb structures. Finite element models were also created to analyse the mechanical behaviour of the honeycombs computationally. The analytical solutions obtained using Timoshenko beam theory were close to computational results in terms of elastic modulus, Poisson's ratio and yield stress, especially for relative densities smaller than 25%. The analytical solutions based on the Timoshenko analytical solution and the computational results were in good agreement with experimental observations. Finally, the elastic properties of the proposed honeycomb structure were compared to those of other honeycomb structures such as square, triangular, hexagonal, mixed, diamond, and Kagome. The octagonal honeycomb showed yield stress and elastic modulus values very close to those of regular hexagonal honeycombs and lower than the other considered honeycombs.

  4. Implementation of Complexity Analyzing Based on Additional Effect

    NASA Astrophysics Data System (ADS)

    Zhang, Peng; Li, Na; Liang, Yanhong; Liu, Fang

    According to the Complexity Theory, there is complexity in the system when the functional requirement is not be satisfied. There are several study performances for Complexity Theory based on Axiomatic Design. However, they focus on reducing the complexity in their study and no one focus on method of analyzing the complexity in the system. Therefore, this paper put forth a method of analyzing the complexity which is sought to make up the deficiency of the researches. In order to discussing the method of analyzing the complexity based on additional effect, this paper put forth two concepts which are ideal effect and additional effect. The method of analyzing complexity based on additional effect combines Complexity Theory with Theory of Inventive Problem Solving (TRIZ). It is helpful for designers to analyze the complexity by using additional effect. A case study shows the application of the process.

  5. Transformation of Breast Reconstruction via Additive Biomanufacturing

    PubMed Central

    Chhaya, Mohit P.; Balmayor, Elizabeth R.; Hutmacher, Dietmar W.; Schantz, Jan-Thorsten

    2016-01-01

    Adipose tissue engineering offers a promising alternative to current breast reconstruction options. However, the conventional approach of using a scaffold in combination with adipose-derived precursor cells poses several problems in terms of scalability and hence clinical feasibility. Following the body-as-a-bioreactor approach, this study proposes a unique concept of delayed fat injection into an additive biomanufactured and custom-made scaffold. Three study groups were evaluated: Empty scaffold, Scaffold containing 4 cm3 lipoaspirate and Empty scaffold +2-week prevascularisation period. In group 3, of prevascularisation, 4 cm3 of lipoaspirate was injected into scaffolds after 2 weeks. Using a well-characterised additive biomanufacturing technology platform, patient-specific scaffolds made of medical-grade-polycaprolactone were designed and fabricated. Scaffolds were implanted in subglandular pockets in immunocompetent minipigs (n = 4) for 24-weeks. Angiogenesis and adipose tissue regeneration were observed in all constructs. Histological evaluation showed that the prevascularisation + lipoaspirate group had the highest relative area of adipose tissue (47.32% ± 4.12) which was significantly higher than both lipoaspirate-only (39.67% ± 2.04) and empty control group (8.31% ± 8.94) and similar to native breast tissue (44.97% ± 14.12). This large preclinical animal study provides proof-of-principle that the clinically applicable prevascularisation and delayed fat-injection techniques can be used for regeneration of large volumes of adipose tissue. PMID:27301425

  6. 16 CFR 1102.16 - Additional information.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... PUBLICLY AVAILABLE CONSUMER PRODUCT SAFETY INFORMATION DATABASE Content Requirements § 1102.16 Additional... in the Database any additional information it determines to be in the public interest,...

  7. 16 CFR 1102.16 - Additional information.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... PUBLICLY AVAILABLE CONSUMER PRODUCT SAFETY INFORMATION DATABASE Content Requirements § 1102.16 Additional... in the Database any additional information it determines to be in the public interest,...

  8. 16 CFR 1102.16 - Additional information.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... PUBLICLY AVAILABLE CONSUMER PRODUCT SAFETY INFORMATION DATABASE Content Requirements § 1102.16 Additional... in the Database any additional information it determines to be in the public interest,...

  9. Nitrogen oxide abatement by distributed fuel addition

    SciTech Connect

    Wendt, J.O.L.; Mereb, J.B.

    1989-06-20

    A combustor has been designed in order to retard the formation of nitrogen oxides by injection of reburning fuel. The design and the rebuilding of the new combustor was completed. Several new features were incorporated in the new design so that it would last longer. The design and construction of the furnace are discussed in this report. (VC)

  10. IN718 Additive Manufacturing Properties and Influences

    NASA Technical Reports Server (NTRS)

    Lambert, Dennis M.

    2015-01-01

    The results of tensile, fracture, and fatigue testing of IN718 coupons produced using the selective laser melting (SLM) additive manufacturing technique are presented. The data has been "generalized" to remove the numerical values, although certain references to material standards are provided. This document provides some knowledge of the effect of variation of controlled build parameters used in the SLM process, a snapshot of the capabilities of SLM in industry at present, and shares some of the lessons learned along the way. For the build parameter characterization, the parameters were varied over a range about the machine manufacturer's recommended value, and in each case they were varied individually, although some co-variance of those parameters would be expected. SLM-produced IN718, tensile, fracture, and high-cycle fatigue properties equivalent to wrought IN718 are achievable. Build and post-build processes need to be determined and then controlled to established limits to accomplish this. It is recommended that a multi-variable evaluation, e.g., design-of-experiment (DOE), of the build parameters be performed to better evaluate the co-variance of the parameters.

  11. Computed tomography characterisation of additive manufacturing materials.

    PubMed

    Bibb, Richard; Thompson, Darren; Winder, John

    2011-06-01

    Additive manufacturing, covering processes frequently referred to as rapid prototyping and rapid manufacturing, provides new opportunities in the manufacture of highly complex and custom-fitting medical devices and products. Whilst many medical applications of AM have been explored and physical properties of the resulting parts have been studied, the characterisation of AM materials in computed tomography has not been explored. The aim of this study was to determine the CT number of commonly used AM materials. There are many potential applications of the information resulting from this study in the design and manufacture of wearable medical devices, implants, prostheses and medical imaging test phantoms. A selection of 19 AM material samples were CT scanned and the resultant images analysed to ascertain the materials' CT number and appearance in the images. It was found that some AM materials have CT numbers very similar to human tissues, FDM, SLA and SLS produce samples that appear uniform on CT images and that 3D printed materials show a variation in internal structure.

  12. IN718 Additive Manufacturing Properties and Influences

    NASA Technical Reports Server (NTRS)

    Lambert, Dennis M.

    2015-01-01

    The results of tensile, fracture, and fatigue testing of IN718 coupons produced using the selective laser melting (SLM) additive manufacturing technique are presented. The data have been "sanitized" to remove the numerical values, although certain references to material standards are provided. This document provides some knowledge of the effect of variation of controlled build parameters used in the SLM process, a snapshot of the capabilities of SLM in industry at present, and shares some of the lessons learned along the way. For the build parameter characterization, the parameters were varied over a range that was centered about the machine manufacturer's recommended value, and in each case they were varied individually, although some co-variance of those parameters would be expected. Tensile, fracture, and high-cycle fatigue properties equivalent to wrought IN718 are achievable with SLM-produced IN718. Build and post-build processes need to be determined and then controlled to established limits to accomplish this. It is recommended that a multi-variable evaluation, e.g., design-of experiment (DOE), of the build parameters be performed to better evaluate the co-variance of the parameters.

  13. Qualitative Reasoning for Additional Die Casting Applications

    SciTech Connect

    R. Allen Miller; Dehua Cui; Yuming Ma

    2003-05-28

    If manufacturing incompatibility of a product can be evaluated at the early product design stage, the designers can modify their design to reduce the effect of potential manufacturing problems. This will result in fewer manufacturing problems, less redsign, less expensive tooling, lower cost, better quality, and shorter development time. For a given design, geometric reasoning can predict qualitatively the behaviors of a physical manufacturing process by representing and reasoning with incomplete knowledge of the physical phenomena. It integrates a design with manufacturing processes to help designers simultaneously consider design goals and manufacturing constraints during the early design stage. The geometric reasoning approach can encourage design engineers to qualitatively evaluate the compatibility of their design with manufacturing limitations and requirements.

  14. Improving designer productivity

    NASA Technical Reports Server (NTRS)

    Hill, Gary C.

    1992-01-01

    Designer and design team productivity improves with skill, experience, and the tools available. The design process involves numerous trials and errors, analyses, refinements, and addition of details. Computerized tools have greatly speeded the analysis, and now new theories and methods, emerging under the label Artificial Intelligence (AI), are being used to automate skill and experience. These tools improve designer productivity by capturing experience, emulating recognized skillful designers, and making the essence of complex programs easier to grasp. This paper outlines the aircraft design process in today's technology and business climate, presenting some of the challenges ahead and some of the promising AI methods for meeting those challenges.

  15. 23 CFR 658.11 - Additions, deletions, exceptions, and restrictions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... AND TRAFFIC OPERATIONS TRUCK SIZE AND WEIGHT, ROUTE DESIGNATIONS-LENGTH, WIDTH AND WEIGHT LIMITATIONS § 658.11 Additions, deletions, exceptions, and restrictions. To ensure that the National Network remains... National Network as well as requests for the imposition of certain restrictions. FHWA approval...

  16. 23 CFR 658.11 - Additions, deletions, exceptions, and restrictions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... AND TRAFFIC OPERATIONS TRUCK SIZE AND WEIGHT, ROUTE DESIGNATIONS-LENGTH, WIDTH AND WEIGHT LIMITATIONS § 658.11 Additions, deletions, exceptions, and restrictions. To ensure that the National Network remains... National Network as well as requests for the imposition of certain restrictions. FHWA approval...

  17. 30 CFR 18.32 - Fastenings-additional requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... and Design Requirements § 18.32 Fastenings—additional requirements. (a) Bolts, screws, or studs shall...) Lockwashers shall be provided for all bolts, screws, and studs that secure parts of explosion-proof enclosures... conduct explosion tests with standard bolts, nuts, cap screws, or studs substituted for any special...

  18. 30 CFR 18.32 - Fastenings-additional requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... and Design Requirements § 18.32 Fastenings—additional requirements. (a) Bolts, screws, or studs shall...) Lockwashers shall be provided for all bolts, screws, and studs that secure parts of explosion-proof enclosures... conduct explosion tests with standard bolts, nuts, cap screws, or studs substituted for any special...

  19. 30 CFR 18.32 - Fastenings-additional requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... and Design Requirements § 18.32 Fastenings—additional requirements. (a) Bolts, screws, or studs shall...) Lockwashers shall be provided for all bolts, screws, and studs that secure parts of explosion-proof enclosures... conduct explosion tests with standard bolts, nuts, cap screws, or studs substituted for any special...

  20. 30 CFR 18.32 - Fastenings-additional requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... and Design Requirements § 18.32 Fastenings—additional requirements. (a) Bolts, screws, or studs shall...) Lockwashers shall be provided for all bolts, screws, and studs that secure parts of explosion-proof enclosures... conduct explosion tests with standard bolts, nuts, cap screws, or studs substituted for any special...

  1. 30 CFR 18.32 - Fastenings-additional requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... and Design Requirements § 18.32 Fastenings—additional requirements. (a) Bolts, screws, or studs shall...) Lockwashers shall be provided for all bolts, screws, and studs that secure parts of explosion-proof enclosures... conduct explosion tests with standard bolts, nuts, cap screws, or studs substituted for any special...

  2. 30 CFR 250.803 - Additional production system requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... reference as specified in 30 CFR 250.198). (b) Design, installation, and operation of additional production... operating pressure ranges of pressure vessels at any time when there is a change in operating pressures that... any time when there is a significant change in operating pressures. The most recent...

  3. 30 CFR 250.803 - Additional production system requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... CFR 250.198). (b) Design, installation, and operation of additional production systems—(1) Pressure... ranges of pressure vessels at any time when there is a change in operating pressures that requires new... significant change in operating pressures. The most recent pressure-recorder charts used to...

  4. Recent Additions to the General College Career Development Program Offerings.

    ERIC Educational Resources Information Center

    Hixson, Bruce, Ed.

    1981-01-01

    Recent additions to the career development offerings at the University of Minnesota's General College are described. The aviation training program, which is described by Thomas Brothen, is designed to prepare students for licensure testing through the Federal Aviation Administration. Background information on aviation training at the University of…

  5. 29 CFR 1602.37 - Additional reporting requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... AND REPORTING REQUIREMENTS UNDER TITLE VII, THE ADA AND GINA State and Local Government Information Report § 1602.37 Additional reporting requirements. The Commission reserves the right to require reports, other than that designated as the “State and Local Government Information Report EEO-4,” about...

  6. 29 CFR 1602.37 - Additional reporting requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... AND REPORTING REQUIREMENTS UNDER TITLE VII, THE ADA AND GINA State and Local Government Information Report § 1602.37 Additional reporting requirements. The Commission reserves the right to require reports, other than that designated as the “State and Local Government Information Report EEO-4,” about...

  7. 29 CFR 1602.37 - Additional reporting requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... AND REPORTING REQUIREMENTS UNDER TITLE VII, THE ADA AND GINA State and Local Government Information Report § 1602.37 Additional reporting requirements. The Commission reserves the right to require reports, other than that designated as the “State and Local Government Information Report EEO-4,” about...

  8. 29 CFR 1602.37 - Additional reporting requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... AND REPORTING REQUIREMENTS UNDER TITLE VII, THE ADA AND GINA State and Local Government Information Report § 1602.37 Additional reporting requirements. The Commission reserves the right to require reports, other than that designated as the “State and Local Government Information Report EEO-4,” about...

  9. 29 CFR 1602.37 - Additional reporting requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... AND REPORTING REQUIREMENTS UNDER TITLE VII, THE ADA AND GINA State and Local Government Information Report § 1602.37 Additional reporting requirements. The Commission reserves the right to require reports, other than that designated as the “State and Local Government Information Report EEO-4,” about...

  10. Automatic Element Addition and Deletion in Lens Optimization

    NASA Astrophysics Data System (ADS)

    Cheng, Xuemin; Wang, Yongtian; Hao, Qun; Sasian, Jose

    2003-03-01

    A mechanism is established for the automatic addition and deletion of optical elements during the course of lens optimization. Two lens-form parameters, quantifying the symmetry of the optical system and the optical-power distribution among the individual lens elements, are used as criteria in this automatic procedure. Design examples are provided that demonstrate the practicability of the scheme.

  11. Teaching Children about the Inverse Relation between Addition and Subtraction

    ERIC Educational Resources Information Center

    Nunes, Terezinha; Bryant, Peter; Hallett, Darcy; Bell, Daniel; Evans, Deborah

    2009-01-01

    Two intervention studies are described. Both were designed to study the effects of teaching children about the inverse relation between addition and subtraction. The interventions were successful with 8-year-old children in Study 1 and to a limited extent with 5-year-old children in Study 2. In Study 1 teaching children about inversion increased…

  12. Septic tank additive impacts on microbial populations.

    PubMed

    Pradhan, S; Hoover, M T; Clark, G H; Gumpertz, M; Wollum, A G; Cobb, C; Strock, J

    2008-01-01

    Environmental health specialists, other onsite wastewater professionals, scientists, and homeowners have questioned the effectiveness of septic tank additives. This paper describes an independent, third-party, field scale, research study of the effects of three liquid bacterial septic tank additives and a control (no additive) on septic tank microbial populations. Microbial populations were measured quarterly in a field study for 12 months in 48 full-size, functioning septic tanks. Bacterial populations in the 48 septic tanks were statistically analyzed with a mixed linear model. Additive effects were assessed for three septic tank maintenance levels (low, intermediate, and high). Dunnett's t-test for tank bacteria (alpha = .05) indicated that none of the treatments were significantly different, overall, from the control at the statistical level tested. In addition, the additives had no significant effects on septic tank bacterial populations at any of the septic tank maintenance levels. Additional controlled, field-based research iswarranted, however, to address additional additives and experimental conditions.

  13. Additive Construction using Basalt Regolith Fines

    NASA Technical Reports Server (NTRS)

    Mueller, Robert P.; Sibille, Laurent; Hintze, Paul E.; Lippitt, Thomas C.; Mantovani, James G.; Nugent, Matthew W.; Townsend, Ivan I.

    2014-01-01

    Planetary surfaces are often covered in regolith (crushed rock), whose geologic origin is largely basalt. The lunar surface is made of small-particulate regolith and areas of boulders located in the vicinity of craters. Regolith composition also varies with location, reflecting the local bedrock geology and the nature and efficiency of the micrometeorite-impact processes. In the lowland mare areas (suitable for habitation), the regolith is composed of small granules (20 - 100 microns average size) of mare basalt and volcanic glass. Impacting micrometeorites may cause local melting, and the formation of larger glassy particles, and this regolith may contain 10-80% glass. Studies of lunar regolith are traditionally conducted with lunar regolith simulant (reconstructed soil with compositions patterned after the lunar samples returned by Apollo). The NASA Kennedy Space Center (KSC) Granular Mechanics & Regolith Operations (GMRO) lab has identified a low fidelity but economical geo-technical simulant designated as Black Point-1 (BP-1). It was found at the site of the Arizona Desert Research and Technology Studies (RATS) analog field test site at the Black Point lava flow in adjacent basalt quarry spoil mounds. This paper summarizes activities at KSC regarding the utilization of BP-1 basalt regolith and comparative work with lunar basalt simulant JSC-1A as a building material for robotic additive construction of large structures. In an effort to reduce the import or in-situ fabrication of binder additives, we focused this work on in-situ processing of regolith for construction in a single-step process after its excavation. High-temperature melting of regolith involves techniques used in glassmaking and casting (with melts of lower density and higher viscosity than those of metals), producing basaltic glass with high durability and low abrasive wear. Most Lunar simulants melt at temperatures above 1100 C, although melt processing of terrestrial regolith at 1500 C is not

  14. Additive Manufacturing of Aerospace Propulsion Components

    NASA Technical Reports Server (NTRS)

    Misra, Ajay K.; Grady, Joseph E.; Carter, Robert

    2015-01-01

    The presentation will provide an overview of ongoing activities on additive manufacturing of aerospace propulsion components, which included rocket propulsion and gas turbine engines. Future opportunities on additive manufacturing of hybrid electric propulsion components will be discussed.

  15. 46 CFR 355.5 - Additional material.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... STATES CITIZENSHIP § 355.5 Additional material. If additional material is determined to be essential to clarify or support the evidence of U.S. citizenship, such material shall be furnished by...

  16. 46 CFR 355.5 - Additional material.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... STATES CITIZENSHIP § 355.5 Additional material. If additional material is determined to be essential to clarify or support the evidence of U.S. citizenship, such material shall be furnished by...

  17. 46 CFR 355.5 - Additional material.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... STATES CITIZENSHIP § 355.5 Additional material. If additional material is determined to be essential to clarify or support the evidence of U.S. citizenship, such material shall be furnished by...

  18. 46 CFR 355.5 - Additional material.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... STATES CITIZENSHIP § 355.5 Additional material. If additional material is determined to be essential to clarify or support the evidence of U.S. citizenship, such material shall be furnished by...

  19. 46 CFR 355.5 - Additional material.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... STATES CITIZENSHIP § 355.5 Additional material. If additional material is determined to be essential to clarify or support the evidence of U.S. citizenship, such material shall be furnished by...

  20. 42 CFR 412.115 - Additional payments.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Payment Systems § 412.115 Additional payments. (a) Bad debts. An additional payment is made to each hospital in accordance with § 413.89 of this chapter for bad debts attributable to deductible...

  1. 42 CFR 412.115 - Additional payments.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Payment Systems § 412.115 Additional payments. (a) Bad debts. An additional payment is made to each hospital in accordance with § 413.89 of this chapter for bad debts attributable to deductible...

  2. 42 CFR 412.115 - Additional payments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Payment Systems § 412.115 Additional payments. (a) Bad debts. An additional payment is made to each hospital in accordance with § 413.89 of this chapter for bad debts attributable to deductible...

  3. 17 CFR 230.408 - Additional information.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Additional information. 230... RULES AND REGULATIONS, SECURITIES ACT OF 1933 General Requirements § 230.408 Additional information. (a) In addition to the information expressly required to be included in a registration statement,...

  4. 17 CFR 230.408 - Additional information.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 2 2013-04-01 2013-04-01 false Additional information. 230... RULES AND REGULATIONS, SECURITIES ACT OF 1933 General Requirements § 230.408 Additional information. (a) In addition to the information expressly required to be included in a registration statement,...

  5. 47 CFR 25.111 - Additional information.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 2 2013-10-01 2013-10-01 false Additional information. 25.111 Section 25.111... Applications and Licenses General Application Filing Requirements § 25.111 Additional information. (a) The Commission may request from any party at any time additional information concerning any application, or...

  6. 10 CFR 810.14 - Additional information.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Additional information. 810.14 Section 810.14 Energy DEPARTMENT OF ENERGY ASSISTANCE TO FOREIGN ATOMIC ENERGY ACTIVITIES § 810.14 Additional information. The... activity to submit additional information....

  7. 47 CFR 25.111 - Additional information.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 2 2012-10-01 2012-10-01 false Additional information. 25.111 Section 25.111... Applications and Licenses General Application Filing Requirements § 25.111 Additional information. (a) The Commission may request from any party at any time additional information concerning any application, or...

  8. 10 CFR 725.13 - Additional information.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Additional information. 725.13 Section 725.13 Energy DEPARTMENT OF ENERGY PERMITS FOR ACCESS TO RESTRICTED DATA Applications § 725.13 Additional information. The... and before the termination of the permit, require additional information in order to enable the...

  9. 47 CFR 25.111 - Additional information.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 2 2011-10-01 2011-10-01 false Additional information. 25.111 Section 25.111... Applications and Licenses General Application Filing Requirements § 25.111 Additional information. (a) The Commission may request from any party at any time additional information concerning any application, or...

  10. 20 CFR 802.215 - Additional briefs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Additional briefs. 802.215 Section 802.215 Employees' Benefits BENEFITS REVIEW BOARD, DEPARTMENT OF LABOR RULES OF PRACTICE AND PROCEDURE Prereview Procedures Initial Processing § 802.215 Additional briefs. Additional briefs may be filed or ordered in...

  11. 10 CFR 55.7 - Additional requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 2 2014-01-01 2014-01-01 false Additional requirements. 55.7 Section 55.7 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) OPERATORS' LICENSES General Provisions § 55.7 Additional requirements. The Commission may, by rule, regulation, or order, impose upon any licensee such requirements, in addition...

  12. 10 CFR 55.7 - Additional requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Additional requirements. 55.7 Section 55.7 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) OPERATORS' LICENSES General Provisions § 55.7 Additional requirements. The Commission may, by rule, regulation, or order, impose upon any licensee such requirements, in addition...

  13. 77 FR 53180 - Procurement List; Additions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-31

    ... INFORMATION: Additions On 6/15/2012 (77 FR 35942-35944) and 6/29/2012 (77 FR 38775-38776), the Committee for... PEOPLE WHO ARE BLIND OR SEVERELY DISABLED Procurement List; Additions AGENCY: Committee for Purchase from People who are Blind or Severely Disabled. ACTION: Additions to the Procurement List. SUMMARY:...

  14. 76 FR 35415 - Procurement List; Addition

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-17

    ... INFORMATION: Additions On 4/29/2011 (76 FR 23998), the Committee for Purchase From People Who Are Blind or... PEOPLE WHO ARE BLIND OR SEVERELY DISABLED Procurement List; Addition AGENCY: Committee for Purchase From People Who Are Blind or Severely Disabled. ACTION: Addition to the Procurement List. SUMMARY: This...

  15. 78 FR 9386 - Procurement List; Addition

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-08

    ... INFORMATION: Addition On 11/30/2012 (77 FR 71400-71401), the Committee for Purchase From People Who Are Blind... PEOPLE WHO ARE BLIND OR SEVERELY DISABLED Procurement List; Addition AGENCY: Committee for Purchase From People Who Are Blind or Severely Disabled. ACTION: Addition to the Procurement List. SUMMARY: This...

  16. 77 FR 31335 - Procurement List; Additions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-25

    ... . SUPPLEMENTARY INFORMATION: Additions On March 16, 2012 (77 FR 15736) and March 23, 2012 (77 FR 17035), the... PEOPLE WHO ARE BLIND OR SEVERELY DISABLED Procurement List; Additions AGENCY: Committee for Purchase From People Who Are Blind or Severely Disabled. ACTION: Additions to the Procurement List. SUMMARY:...

  17. 76 FR 19751 - Procurement List; Addition

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-08

    ... INFORMATION: Addition On 1/28/2011 (76 FR 5142-5143), the Committee for Purchase From People Who Are Blind or... PEOPLE WHO ARE BLIND OR SEVERELY DISABLED Procurement List; Addition AGENCY: Committee for Purchase From People Who Are Blind or Severely Disabled. ACTION: Addition to the Procurement List. SUMMARY: This...

  18. 75 FR 4784 - Procurement List; Addition

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-29

    ... INFORMATION: Addition On 11/16/2009 (74 FR 58949-58950), the Committee for Purchase From People Who Are Blind... PEOPLE WHO ARE BLIND OR SEVERELY DISABLED Procurement List; Addition AGENCY: Committee for Purchase From People Who Are Blind or Severely Disabled. ACTION: Addition to the Procurement List. SUMMARY: This...

  19. 76 FR 23997 - Procurement List; Addition

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-29

    ... INFORMATION: Addition On 2/25/2011 (76 FR 10571), the Committee for Purchase From People Who Are Blind or... PEOPLE WHO ARE BLIND OR SEVERELY DISABLED Procurement List; Addition AGENCY: Committee for Purchase From People Who Are Blind or Severely Disabled. ACTION: Addition to the Procurement List. SUMMARY: This...

  20. 75 FR 22745 - Procurement List Additions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-30

    ... INFORMATION: Additions On 10/23/2009 (74 FR 54783-54784) and 3/5/2010 (75 FR 10223-10224), the Committee for... PEOPLE WHO ARE BLIND OR SEVERELY DISABLED Procurement List Additions AGENCY: Committee for Purchase From People Who Are Blind or Severely Disabled. ACTION: Additions to the Procurement List. SUMMARY:...

  1. 77 FR 71400 - Procurement List, Additions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-30

    ... . SUPPLEMENTARY INFORMATION: Additions On 8/24/2012 (77 FR 51522-51523) and 10/5/2012 (77 FR 60969), the Committee... PEOPLE WHO ARE BLIND OR SEVERELY DISABLED Procurement List, Additions AGENCY: Committee for Purchase From People Who Are Blind or Severely Disabled. ACTION: Additions to the Procurement List. SUMMARY:...

  2. 75 FR 72815 - Procurement List Additions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-26

    ... INFORMATION: Additions On 6/4/2010 (75 FR 31768-31769) and 10/1/2010 (75 FR 60739-60740), the Committee for... PEOPLE WHO ARE BLIND OR SEVERELY DISABLED Procurement List Additions AGENCY: Committee for Purchase From People Who Are Blind or Severely Disabled. ACTION: Additions to the Procurement List. SUMMARY:...

  3. 77 FR 59595 - Procurement List; Additions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-28

    ... . SUPPLEMENTARY INFORMATION: Additions On 7/9/2012 (77 FR 40344-40345) and 7/20/2012 (77 FR 42701-42702), the... PEOPLE WHO ARE BLIND OR SEVERELY DISABLED Procurement List; Additions AGENCY: Committee for Purchase From People Who Are Blind or Severely Disabled. ACTION: Additions to the Procurement List. SUMMARY:...

  4. 77 FR 34025 - Procurement List; Addition

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-08

    ... INFORMATION: ] Addition On 4/132012 (77 FR 22289-22290), the Committee for Purchase From People Who Are Blind... PEOPLE WHO ARE BLIND OR SEVERELY DISABLED Procurement List; Addition AGENCY: Committee for Purchase From People Who Are Blind or Severely Disabled. ACTION: Addition to the Procurement List. SUMMARY: This...

  5. 78 FR 2378 - Procurement List, Addition

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-11

    ... INFORMATION: Addition On 11/9/2012 (77 FR 67343-67344), the Committee for Purchase From People Who Are Blind... PEOPLE WHO ARE BLIND OR SEVERELY DISABLED Procurement List, Addition AGENCY: Committee for Purchase From People Who Are Blind or Severely Disabled. ACTION: Addition to the Procurement List. SUMMARY: This...

  6. 76 FR 54741 - Procurement List; Additions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-02

    ... INFORMATION: Additions On 7/8/2011 (76 FR 40342-40343), the Committee for Purchase From People Who Are Blind... PEOPLE WHO ARE BLIND OR SEVERELY DISABLED Procurement List; Additions AGENCY: Committee for Purchase From People Who Are Blind or Severely Disabled. ACTION: Additions to the Procurement List. SUMMARY:...

  7. Polymeric Additives For Graphite/Epoxy Composites

    NASA Technical Reports Server (NTRS)

    Kourtides, D. A.; Nir, Z.

    1990-01-01

    Report describes experimental studies of properties of several graphite/epoxy composites containing polymeric additives as flexibilizing or toughening agents. Emphasizes effects of brominated polymeric additives (BPA's) with or without carboxy-terminated butadiene acrylonitrile rubber. Reviews effects of individual and combined additives on fracture toughnesses, environmental stabilities, hot/wet strengths, thermomechanical behaviors, and other mechanical properties of composites.

  8. 14 CFR 29.927 - Additional tests.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Additional tests. 29.927 Section 29.927... STANDARDS: TRANSPORT CATEGORY ROTORCRAFT Powerplant Rotor Drive System § 29.927 Additional tests. (a) Any additional dynamic, endurance, and operational tests, and vibratory investigations necessary to...

  9. 14 CFR 27.927 - Additional tests.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Additional tests. 27.927 Section 27.927... STANDARDS: NORMAL CATEGORY ROTORCRAFT Powerplant Rotor Drive System § 27.927 Additional tests. (a) Any additional dynamic, endurance, and operational tests, and vibratory investigations necessary to...

  10. 14 CFR 29.927 - Additional tests.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Additional tests. 29.927 Section 29.927... STANDARDS: TRANSPORT CATEGORY ROTORCRAFT Powerplant Rotor Drive System § 29.927 Additional tests. (a) Any additional dynamic, endurance, and operational tests, and vibratory investigations necessary to...

  11. 14 CFR 27.927 - Additional tests.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Additional tests. 27.927 Section 27.927... STANDARDS: NORMAL CATEGORY ROTORCRAFT Powerplant Rotor Drive System § 27.927 Additional tests. (a) Any additional dynamic, endurance, and operational tests, and vibratory investigations necessary to...

  12. 14 CFR 29.927 - Additional tests.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Additional tests. 29.927 Section 29.927... STANDARDS: TRANSPORT CATEGORY ROTORCRAFT Powerplant Rotor Drive System § 29.927 Additional tests. (a) Any additional dynamic, endurance, and operational tests, and vibratory investigations necessary to...

  13. 14 CFR 27.927 - Additional tests.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Additional tests. 27.927 Section 27.927... STANDARDS: NORMAL CATEGORY ROTORCRAFT Powerplant Rotor Drive System § 27.927 Additional tests. (a) Any additional dynamic, endurance, and operational tests, and vibratory investigations necessary to...

  14. 7 CFR 1944.686 - Additional grants.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 13 2011-01-01 2009-01-01 true Additional grants. 1944.686 Section 1944.686...) PROGRAM REGULATIONS (CONTINUED) HOUSING Housing Preservation Grants § 1944.686 Additional grants. An additional HPG grant may be made when the grantee has achieved or nearly achieved the goals established...

  15. 7 CFR 1944.545 - Additional grants.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 13 2013-01-01 2013-01-01 false Additional grants. 1944.545 Section 1944.545...) PROGRAM REGULATIONS (CONTINUED) HOUSING Technical and Supervisory Assistance Grants § 1944.545 Additional grants. An additional grant may be made to an applicant that has previously received a TSA grant and...

  16. 7 CFR 1944.545 - Additional grants.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 13 2011-01-01 2009-01-01 true Additional grants. 1944.545 Section 1944.545...) PROGRAM REGULATIONS (CONTINUED) HOUSING Technical and Supervisory Assistance Grants § 1944.545 Additional grants. An additional grant may be made to an applicant that has previously received a TSA grant and...

  17. 7 CFR 1944.686 - Additional grants.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 13 2013-01-01 2013-01-01 false Additional grants. 1944.686 Section 1944.686...) PROGRAM REGULATIONS (CONTINUED) HOUSING Housing Preservation Grants § 1944.686 Additional grants. An additional HPG grant may be made when the grantee has achieved or nearly achieved the goals established...

  18. 24 CFR 964.410 - Additional definitions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 4 2012-04-01 2012-04-01 false Additional definitions. 964.410... Additional definitions. The following additional definitions apply to this subpart only: Directly assisted... assisted by a public housing agency; (2) Whose name appears on the lease; and (3) Is eighteen years of...

  19. 24 CFR 964.410 - Additional definitions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false Additional definitions. 964.410... Additional definitions. The following additional definitions apply to this subpart only: Directly assisted... assisted by a public housing agency; (2) Whose name appears on the lease; and (3) Is eighteen years of...

  20. 24 CFR 964.410 - Additional definitions.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 4 2013-04-01 2013-04-01 false Additional definitions. 964.410... Additional definitions. The following additional definitions apply to this subpart only: Directly assisted... assisted by a public housing agency; (2) Whose name appears on the lease; and (3) Is eighteen years of...