38 CFR 36.4207 - Manufactured home standards.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2011-07-01 2011-07-01 false Manufactured home... (CONTINUED) LOAN GUARANTY Guaranty of Loans to Veterans to Purchase Manufactured Homes and Lots, Including Site Preparation General Provisions § 36.4207 Manufactured home standards. To qualify for purchase with...

38 CFR 36.4207 - Manufactured home standards.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2014-07-01 2014-07-01 false Manufactured home... (CONTINUED) LOAN GUARANTY Guaranty of Loans to Veterans to Purchase Manufactured Homes and Lots, Including Site Preparation General Provisions § 36.4207 Manufactured home standards. To qualify for purchase with...

24 CFR 982.620 - Manufactured home: Applicability of requirements.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false Manufactured home: Applicability of... Types Manufactured Home § 982.620 Manufactured home: Applicability of requirements. (a) Assistance for resident of manufactured home. (1) A family may reside in a manufactured home with assistance under the...

24 CFR 982.621 - Manufactured home: Housing quality standards.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false Manufactured home: Housing quality... Types Manufactured Home § 982.621 Manufactured home: Housing quality standards. A manufactured home must meet all the HQS performance requirements and acceptability criteria in § 982.401. A manufactured home...

24 CFR 982.621 - Manufactured home: Housing quality standards.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 24 Housing and Urban Development 4 2012-04-01 2012-04-01 false Manufactured home: Housing quality... Types Manufactured Home § 982.621 Manufactured home: Housing quality standards. A manufactured home must meet all the HQS performance requirements and acceptability criteria in § 982.401. A manufactured home...

24 CFR 982.620 - Manufactured home: Applicability of requirements.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 24 Housing and Urban Development 4 2012-04-01 2012-04-01 false Manufactured home: Applicability of... Types Manufactured Home § 982.620 Manufactured home: Applicability of requirements. (a) Assistance for resident of manufactured home. (1) A family may reside in a manufactured home with assistance under the...

24 CFR 982.621 - Manufactured home: Housing quality standards.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Manufactured home: Housing quality... Types Manufactured Home § 982.621 Manufactured home: Housing quality standards. A manufactured home must meet all the HQS performance requirements and acceptability criteria in § 982.401. A manufactured home...

24 CFR 982.620 - Manufactured home: Applicability of requirements.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 4 2013-04-01 2013-04-01 false Manufactured home: Applicability of... Types Manufactured Home § 982.620 Manufactured home: Applicability of requirements. (a) Assistance for resident of manufactured home. (1) A family may reside in a manufactured home with assistance under the...

24 CFR 982.621 - Manufactured home: Housing quality standards.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 4 2013-04-01 2013-04-01 false Manufactured home: Housing quality... Types Manufactured Home § 982.621 Manufactured home: Housing quality standards. A manufactured home must meet all the HQS performance requirements and acceptability criteria in § 982.401. A manufactured home...

24 CFR 982.621 - Manufactured home: Housing quality standards.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 4 2014-04-01 2014-04-01 false Manufactured home: Housing quality... Types Manufactured Home § 982.621 Manufactured home: Housing quality standards. A manufactured home must meet all the HQS performance requirements and acceptability criteria in § 982.401. A manufactured home...

24 CFR 982.620 - Manufactured home: Applicability of requirements.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Manufactured home: Applicability of... Types Manufactured Home § 982.620 Manufactured home: Applicability of requirements. (a) Assistance for resident of manufactured home. (1) A family may reside in a manufactured home with assistance under the...

24 CFR 982.620 - Manufactured home: Applicability of requirements.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 4 2014-04-01 2014-04-01 false Manufactured home: Applicability of... Types Manufactured Home § 982.620 Manufactured home: Applicability of requirements. (a) Assistance for resident of manufactured home. (1) A family may reside in a manufactured home with assistance under the...

24 CFR 1710.11 - Manufactured home exemption.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 24 Housing and Urban Development 5 2012-04-01 2012-04-01 false Manufactured home exemption. 1710... Requirements § 1710.11 Manufactured home exemption. (a) The sale of a lot is exempt from the registration... by one party and a manufactured home is sold by another party and the contracts of sale— (i) Obligate...

24 CFR 1710.11 - Manufactured home exemption.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 5 2013-04-01 2013-04-01 false Manufactured home exemption. 1710... Requirements § 1710.11 Manufactured home exemption. (a) The sale of a lot is exempt from the registration... by one party and a manufactured home is sold by another party and the contracts of sale— (i) Obligate...

24 CFR 1710.11 - Manufactured home exemption.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 5 2010-04-01 2010-04-01 false Manufactured home exemption. 1710... Requirements § 1710.11 Manufactured home exemption. (a) The sale of a lot is exempt from the registration... by one party and a manufactured home is sold by another party and the contracts of sale— (i) Obligate...

24 CFR 1710.11 - Manufactured home exemption.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 5 2011-04-01 2011-04-01 false Manufactured home exemption. 1710... Requirements § 1710.11 Manufactured home exemption. (a) The sale of a lot is exempt from the registration... by one party and a manufactured home is sold by another party and the contracts of sale— (i) Obligate...

24 CFR 1710.11 - Manufactured home exemption.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 5 2014-04-01 2014-04-01 false Manufactured home exemption. 1710... Requirements § 1710.11 Manufactured home exemption. (a) The sale of a lot is exempt from the registration... by one party and a manufactured home is sold by another party and the contracts of sale— (i) Obligate...

24 CFR 201.21 - Manufactured home loan eligibility.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Manufactured home loan eligibility... AUTHORITIES TITLE I PROPERTY IMPROVEMENT AND MANUFACTURED HOME LOANS Eligibility and Disbursement Requirements § 201.21 Manufactured home loan eligibility. (a) Borrower eligibility. To be eligible for a manufactured...

24 CFR 201.21 - Manufactured home loan eligibility.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 2 2013-04-01 2013-04-01 false Manufactured home loan eligibility... AUTHORITIES TITLE I PROPERTY IMPROVEMENT AND MANUFACTURED HOME LOANS Eligibility and Disbursement Requirements § 201.21 Manufactured home loan eligibility. (a) Borrower eligibility. To be eligible for a manufactured...

24 CFR 201.21 - Manufactured home loan eligibility.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Manufactured home loan eligibility... AUTHORITIES TITLE I PROPERTY IMPROVEMENT AND MANUFACTURED HOME LOANS Eligibility and Disbursement Requirements § 201.21 Manufactured home loan eligibility. (a) Borrower eligibility. To be eligible for a manufactured...

24 CFR 201.21 - Manufactured home loan eligibility.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Manufactured home loan eligibility... AUTHORITIES TITLE I PROPERTY IMPROVEMENT AND MANUFACTURED HOME LOANS Eligibility and Disbursement Requirements § 201.21 Manufactured home loan eligibility. (a) Borrower eligibility. To be eligible for a manufactured...

12 CFR 1010.11 - Manufactured home exemption.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 12 Banks and Banking 8 2014-01-01 2014-01-01 false Manufactured home exemption. 1010.11 Section...) General Requirements § 1010.11 Manufactured home exemption. (a) The sale of a lot is exempt from the... as a homesite by one party and a manufactured home is sold by another party and the contracts of sale...

12 CFR 1010.11 - Manufactured home exemption.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 12 Banks and Banking 8 2013-01-01 2013-01-01 false Manufactured home exemption. 1010.11 Section...) General Requirements § 1010.11 Manufactured home exemption. (a) The sale of a lot is exempt from the... as a homesite by one party and a manufactured home is sold by another party and the contracts of sale...

12 CFR 1010.11 - Manufactured home exemption.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 12 Banks and Banking 8 2012-01-01 2012-01-01 false Manufactured home exemption. 1010.11 Section...) General Requirements § 1010.11 Manufactured home exemption. (a) The sale of a lot is exempt from the... as a homesite by one party and a manufactured home is sold by another party and the contracts of sale...

76 FR 22117 - Notice of Submission of Proposed Information Collection to OMB Manufactured Home Construction and...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-20

... Proposed Information Collection to OMB Manufactured Home Construction and Safety Standards Act Reporting... home producers to place labels and notices in and on manufactured homes and mandate State and Private...' interests by requiring certain features of design and construction. In addition, information collected...

Technology Solutions Case Study: Southern Energy Homes, First DOE Zero Energy Ready Manufactured Home

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

The country’s first Zero Energy Ready manufactured home that is certified by the U.S. Department of Energy (DOE) is up and running in Russellville, Alabama. The manufactured home was built by a partnership between Southern Energy Homes and the Advanced Residential Integrated Energy Solutions Collaborative (ARIES), which is a DOE Building America team. The effort was part of a three-home study including a standard-code manufactured home and an ENERGY STAR® manufactured home. Cooling-season results showed that the building used half the space-conditioning energy of a manufactured home built to the U.S. Department of Housing and Urban Development’s (HUD’s) Manufactured Homemore » Construction and Safety Standards. These standards are known collectively as the HUD Code, which is the building standard for all U.S. manufactured housing.« less

24 CFR 3285.6 - Final leveling of manufactured home.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 24 Housing and Urban Development 5 2012-04-01 2012-04-01 false Final leveling of manufactured home... HOUSING AND URBAN DEVELOPMENT MODEL MANUFACTURED HOME INSTALLATION STANDARDS General § 3285.6 Final leveling of manufactured home. The manufactured home must be adequately leveled prior to completion of the...

24 CFR 3285.6 - Final leveling of manufactured home.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 5 2011-04-01 2011-04-01 false Final leveling of manufactured home... HOUSING AND URBAN DEVELOPMENT MODEL MANUFACTURED HOME INSTALLATION STANDARDS General § 3285.6 Final leveling of manufactured home. The manufactured home must be adequately leveled prior to completion of the...

24 CFR 3285.6 - Final leveling of manufactured home.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 5 2014-04-01 2014-04-01 false Final leveling of manufactured home... HOUSING AND URBAN DEVELOPMENT MODEL MANUFACTURED HOME INSTALLATION STANDARDS General § 3285.6 Final leveling of manufactured home. The manufactured home must be adequately leveled prior to completion of the...

24 CFR 3285.6 - Final leveling of manufactured home.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 5 2010-04-01 2010-04-01 false Final leveling of manufactured home... HOUSING AND URBAN DEVELOPMENT MODEL MANUFACTURED HOME INSTALLATION STANDARDS General § 3285.6 Final leveling of manufactured home. The manufactured home must be adequately leveled prior to completion of the...

24 CFR 3285.6 - Final leveling of manufactured home.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 5 2013-04-01 2013-04-01 false Final leveling of manufactured home... HOUSING AND URBAN DEVELOPMENT MODEL MANUFACTURED HOME INSTALLATION STANDARDS General § 3285.6 Final leveling of manufactured home. The manufactured home must be adequately leveled prior to completion of the...

16 CFR Appendix G5 to Part 305 - Mobile Home Furnaces-Oil

Code of Federal Regulations, 2014 CFR

2014-01-01

... 16 Commercial Practices 1 2014-01-01 2014-01-01 false Mobile Home Furnaces-Oil G5 Appendix G5 to... LABELING RULEâ) Appendix G5 to Part 305—Mobile Home Furnaces—Oil Type Range of annual fuel utilization efficiencies (AFUEs) Low High Mobile Home Oil Furnaces Manufactured Before the Compliance Date of DOE Regional...

16 CFR Appendix G4 to Part 305 - Mobile Home Furnaces-Gas

Code of Federal Regulations, 2014 CFR

2014-01-01

... 16 Commercial Practices 1 2014-01-01 2014-01-01 false Mobile Home Furnaces-Gas G4 Appendix G4 to... LABELING RULEâ) Appendix G4 to Part 305—Mobile Home Furnaces—Gas Type Range of annual fuel utilization efficiencies (AFUEs) Low High Mobile Home Gas Furnaces Manufactured Before the Compliance Date of DOE Regional...

38 CFR 36.4208 - Manufactured home location standards.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2011-07-01 2011-07-01 false Manufactured home... AFFAIRS (CONTINUED) LOAN GUARANTY Guaranty of Loans to Veterans to Purchase Manufactured Homes and Lots, Including Site Preparation General Provisions § 36.4208 Manufactured home location standards. (a) Any rental...

38 CFR 36.4208 - Manufactured home location standards.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Manufactured home... AFFAIRS (CONTINUED) LOAN GUARANTY Guaranty of Loans to Veterans to Purchase Manufactured Homes and Lots, Including Site Preparation General Provisions § 36.4208 Manufactured home location standards. (a) Any rental...

38 CFR 36.4208 - Manufactured home location standards.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2012-07-01 2012-07-01 false Manufactured home... AFFAIRS (CONTINUED) LOAN GUARANTY Guaranty of Loans to Veterans to Purchase Manufactured Homes and Lots, Including Site Preparation General Provisions § 36.4208 Manufactured home location standards. (a) Any rental...

38 CFR 36.4208 - Manufactured home location standards.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2013-07-01 2013-07-01 false Manufactured home... AFFAIRS (CONTINUED) LOAN GUARANTY Guaranty of Loans to Veterans to Purchase Manufactured Homes and Lots, Including Site Preparation General Provisions § 36.4208 Manufactured home location standards. (a) Any rental...

38 CFR 36.4208 - Manufactured home location standards.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2014-07-01 2014-07-01 false Manufactured home... AFFAIRS (CONTINUED) LOAN GUARANTY Guaranty of Loans to Veterans to Purchase Manufactured Homes and Lots, Including Site Preparation General Provisions § 36.4208 Manufactured home location standards. (a) Any rental...

24 CFR 3285.902 - Moving manufactured home to location.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 5 2011-04-01 2011-04-01 false Moving manufactured home to... HOUSING AND URBAN DEVELOPMENT MODEL MANUFACTURED HOME INSTALLATION STANDARDS Optional Information for Manufacturer's Installation Instructions § 3285.902 Moving manufactured home to location. It is recommended...

24 CFR 3282.207 - Manufactured home consumer manual requirements.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 5 2014-04-01 2014-04-01 false Manufactured home consumer manual... HOUSING AND URBAN DEVELOPMENT MANUFACTURED HOME PROCEDURAL AND ENFORCEMENT REGULATIONS Manufacturer Inspection and Certification Requirements § 3282.207 Manufactured home consumer manual requirements. (a) The...

24 CFR 3285.902 - Moving manufactured home to location.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 24 Housing and Urban Development 5 2012-04-01 2012-04-01 false Moving manufactured home to... HOUSING AND URBAN DEVELOPMENT MODEL MANUFACTURED HOME INSTALLATION STANDARDS Optional Information for Manufacturer's Installation Instructions § 3285.902 Moving manufactured home to location. It is recommended...

24 CFR 3285.902 - Moving manufactured home to location.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 5 2010-04-01 2010-04-01 false Moving manufactured home to... HOUSING AND URBAN DEVELOPMENT MODEL MANUFACTURED HOME INSTALLATION STANDARDS Optional Information for Manufacturer's Installation Instructions § 3285.902 Moving manufactured home to location. It is recommended...

24 CFR 3282.207 - Manufactured home consumer manual requirements.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 24 Housing and Urban Development 5 2012-04-01 2012-04-01 false Manufactured home consumer manual... HOUSING AND URBAN DEVELOPMENT MANUFACTURED HOME PROCEDURAL AND ENFORCEMENT REGULATIONS Manufacturer Inspection and Certification Requirements § 3282.207 Manufactured home consumer manual requirements. (a) The...

24 CFR 3285.902 - Moving manufactured home to location.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 5 2014-04-01 2014-04-01 false Moving manufactured home to... HOUSING AND URBAN DEVELOPMENT MODEL MANUFACTURED HOME INSTALLATION STANDARDS Optional Information for Manufacturer's Installation Instructions § 3285.902 Moving manufactured home to location. It is recommended...

24 CFR 3282.207 - Manufactured home consumer manual requirements.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 5 2013-04-01 2013-04-01 false Manufactured home consumer manual... HOUSING AND URBAN DEVELOPMENT MANUFACTURED HOME PROCEDURAL AND ENFORCEMENT REGULATIONS Manufacturer Inspection and Certification Requirements § 3282.207 Manufactured home consumer manual requirements. (a) The...

24 CFR 3282.207 - Manufactured home consumer manual requirements.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 5 2011-04-01 2011-04-01 false Manufactured home consumer manual... HOUSING AND URBAN DEVELOPMENT MANUFACTURED HOME PROCEDURAL AND ENFORCEMENT REGULATIONS Manufacturer Inspection and Certification Requirements § 3282.207 Manufactured home consumer manual requirements. (a) The...

24 CFR 3285.902 - Moving manufactured home to location.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 5 2013-04-01 2013-04-01 false Moving manufactured home to... HOUSING AND URBAN DEVELOPMENT MODEL MANUFACTURED HOME INSTALLATION STANDARDS Optional Information for Manufacturer's Installation Instructions § 3285.902 Moving manufactured home to location. It is recommended...

Technology Solutions for New Manufactured Homes: Idaho, Oregon, and Washington Manufactured Home Builders (Fact Sheet)

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

2013-11-01

The Building America Partnership for Improved Residential Construction, the Bonneville Power Administration (BPA), and Northwest Energy Works (NEW), the current Northwest Energy Efficient Manufactured Housing Program (NEEM) administrator, have been collaborating to conduct research on new specifications that would improve on the energy requirements of a NEEM home. In its role as administrator, NEW administers the technical specs, performs research and engineering analysis, implements ongoing construction quality management procedures, and maintains a central database with home tracking. This project prototyped and assessed the performances of cost-effective high performance building assemblies and mechanical systems that are not commonly deployed in themore » manufacturing setting. The package of measures is able to reduce energy used for space conditioning, water heating and lighting by 50 percent over typical manufactured homes produced in the northwest.« less

16 CFR 460.16 - What new home sellers must tell new home buyers.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 16 Commercial Practices 1 2011-01-01 2011-01-01 false What new home sellers must tell new home... LABELING AND ADVERTISING OF HOME INSULATION § 460.16 What new home sellers must tell new home buyers. If you are a new home seller, you must put the following information in every sales contract: The type...

16 CFR 460.16 - What new home sellers must tell new home buyers.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 16 Commercial Practices 1 2013-01-01 2013-01-01 false What new home sellers must tell new home... LABELING AND ADVERTISING OF HOME INSULATION § 460.16 What new home sellers must tell new home buyers. If you are a new home seller, you must put the following information in every sales contract: The type...

16 CFR 460.16 - What new home sellers must tell new home buyers.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 16 Commercial Practices 1 2010-01-01 2010-01-01 false What new home sellers must tell new home... LABELING AND ADVERTISING OF HOME INSULATION § 460.16 What new home sellers must tell new home buyers. If you are a new home seller, you must put the following information in every sales contract: The type...

16 CFR 460.16 - What new home sellers must tell new home buyers.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 16 Commercial Practices 1 2012-01-01 2012-01-01 false What new home sellers must tell new home... LABELING AND ADVERTISING OF HOME INSULATION § 460.16 What new home sellers must tell new home buyers. If you are a new home seller, you must put the following information in every sales contract: The type...

16 CFR 460.16 - What new home sellers must tell new home buyers.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 16 Commercial Practices 1 2014-01-01 2014-01-01 false What new home sellers must tell new home... LABELING AND ADVERTISING OF HOME INSULATION § 460.16 What new home sellers must tell new home buyers. If you are a new home seller, you must put the following information in every sales contract: The type...

24 CFR 982.623 - Manufactured home space rental: Housing assistance payment.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 4 2014-04-01 2014-04-01 false Manufactured home space rental... Special Housing Types Manufactured Home Space Rental § 982.623 Manufactured home space rental: Housing...) Manufactured home space cost minus the total tenant payment. (ii) The rent to owner for the manufactured home...

24 CFR 982.623 - Manufactured home space rental: Housing assistance payment.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Manufactured home space rental... Special Housing Types Manufactured Home Space Rental § 982.623 Manufactured home space rental: Housing...) Manufactured home space cost minus the total tenant payment. (ii) The rent to owner for the manufactured home...

24 CFR 982.623 - Manufactured home space rental: Housing assistance payment.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false Manufactured home space rental... Special Housing Types Manufactured Home Space Rental § 982.623 Manufactured home space rental: Housing...) Manufactured home space cost minus the total tenant payment. (ii) The rent to owner for the manufactured home...

24 CFR 3285.104 - Moving manufactured home to location.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 5 2013-04-01 2013-04-01 false Moving manufactured home to... HOUSING AND URBAN DEVELOPMENT MODEL MANUFACTURED HOME INSTALLATION STANDARDS Pre-Installation Considerations § 3285.104 Moving manufactured home to location. Refer to § 3285.902 for considerations related to...

24 CFR 3282.14 - Alternative construction of manufactured homes.

Code of Federal Regulations, 2010 CFR

2010-04-01

... manufactured homes. 3282.14 Section 3282.14 Housing and Urban Development Regulations Relating to Housing and..., DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT MANUFACTURED HOME PROCEDURAL AND ENFORCEMENT REGULATIONS General § 3282.14 Alternative construction of manufactured homes. (a) Policy. In order to promote the purposes of...

24 CFR 3282.14 - Alternative construction of manufactured homes.

Code of Federal Regulations, 2011 CFR

2011-04-01

... manufactured homes. 3282.14 Section 3282.14 Housing and Urban Development Regulations Relating to Housing and..., DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT MANUFACTURED HOME PROCEDURAL AND ENFORCEMENT REGULATIONS General § 3282.14 Alternative construction of manufactured homes. (a) Policy. In order to promote the purposes of...

24 CFR 3282.14 - Alternative construction of manufactured homes.

Code of Federal Regulations, 2012 CFR

2012-04-01

... manufactured homes. 3282.14 Section 3282.14 Housing and Urban Development Regulations Relating to Housing and..., DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT MANUFACTURED HOME PROCEDURAL AND ENFORCEMENT REGULATIONS General § 3282.14 Alternative construction of manufactured homes. (a) Policy. In order to promote the purposes of...

24 CFR 3285.104 - Moving manufactured home to location.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 5 2011-04-01 2011-04-01 false Moving manufactured home to... HOUSING AND URBAN DEVELOPMENT MODEL MANUFACTURED HOME INSTALLATION STANDARDS Pre-Installation Considerations § 3285.104 Moving manufactured home to location. Refer to § 3285.902 for considerations related to...

24 CFR 3282.14 - Alternative construction of manufactured homes.

Code of Federal Regulations, 2014 CFR

2014-04-01

... manufactured homes. 3282.14 Section 3282.14 Housing and Urban Development Regulations Relating to Housing and..., DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT MANUFACTURED HOME PROCEDURAL AND ENFORCEMENT REGULATIONS General § 3282.14 Alternative construction of manufactured homes. (a) Policy. In order to promote the purposes of...

24 CFR 3285.104 - Moving manufactured home to location.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 5 2014-04-01 2014-04-01 false Moving manufactured home to... HOUSING AND URBAN DEVELOPMENT MODEL MANUFACTURED HOME INSTALLATION STANDARDS Pre-Installation Considerations § 3285.104 Moving manufactured home to location. Refer to § 3285.902 for considerations related to...

24 CFR 3285.104 - Moving manufactured home to location.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 24 Housing and Urban Development 5 2012-04-01 2012-04-01 false Moving manufactured home to... HOUSING AND URBAN DEVELOPMENT MODEL MANUFACTURED HOME INSTALLATION STANDARDS Pre-Installation Considerations § 3285.104 Moving manufactured home to location. Refer to § 3285.902 for considerations related to...

24 CFR 3285.104 - Moving manufactured home to location.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 5 2010-04-01 2010-04-01 false Moving manufactured home to... HOUSING AND URBAN DEVELOPMENT MODEL MANUFACTURED HOME INSTALLATION STANDARDS Pre-Installation Considerations § 3285.104 Moving manufactured home to location. Refer to § 3285.902 for considerations related to...

24 CFR 3282.14 - Alternative construction of manufactured homes.

Code of Federal Regulations, 2013 CFR

2013-04-01

... manufactured homes. 3282.14 Section 3282.14 Housing and Urban Development Regulations Relating to Housing and..., DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT MANUFACTURED HOME PROCEDURAL AND ENFORCEMENT REGULATIONS General § 3282.14 Alternative construction of manufactured homes. (a) Policy. In order to promote the purposes of...

7 CFR 3555.208 - Special requirements for manufactured homes.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 15 2014-01-01 2014-01-01 false Special requirements for manufactured homes. 3555.208... Property § 3555.208 Special requirements for manufactured homes. Loans may be guaranteed for manufactured homes if all the requirements in this section are met. (a) Eligible costs. In addition to the loan...

24 CFR 982.624 - Manufactured home space rental: Utility allowance schedule.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false Manufactured home space rental... Special Housing Types Manufactured Home Space Rental § 982.624 Manufactured home space rental: Utility allowance schedule. The PHA must establish utility allowances for manufactured home space rental. For the...

38 CFR 36.4232 - Allowable fees and charges; manufactured home unit.

Code of Federal Regulations, 2013 CFR

2013-07-01

... charges; manufactured home unit. 36.4232 Section 36.4232 Pensions, Bonuses, and Veterans' Relief... Manufactured Homes and Lots, Including Site Preparation Financing Manufactured Home Units § 36.4232 Allowable fees and charges; manufactured home unit. (a) Incident to the origination of a guaranteed loan for the...

38 CFR 36.4232 - Allowable fees and charges; manufactured home unit.

Code of Federal Regulations, 2010 CFR

2010-07-01

... charges; manufactured home unit. 36.4232 Section 36.4232 Pensions, Bonuses, and Veterans' Relief... Manufactured Homes and Lots, Including Site Preparation Financing Manufactured Home Units § 36.4232 Allowable fees and charges; manufactured home unit. (a) Incident to the origination of a guaranteed loan for the...

38 CFR 36.4232 - Allowable fees and charges; manufactured home unit.

Code of Federal Regulations, 2012 CFR

2012-07-01

... charges; manufactured home unit. 36.4232 Section 36.4232 Pensions, Bonuses, and Veterans' Relief... Manufactured Homes and Lots, Including Site Preparation Financing Manufactured Home Units § 36.4232 Allowable fees and charges; manufactured home unit. (a) Incident to the origination of a guaranteed loan for the...

24 CFR 982.624 - Manufactured home space rental: Utility allowance schedule.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Manufactured home space rental... Special Housing Types Manufactured Home Space Rental § 982.624 Manufactured home space rental: Utility allowance schedule. The PHA must establish utility allowances for manufactured home space rental. For the...

24 CFR 982.624 - Manufactured home space rental: Utility allowance schedule.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 4 2014-04-01 2014-04-01 false Manufactured home space rental... Special Housing Types Manufactured Home Space Rental § 982.624 Manufactured home space rental: Utility allowance schedule. The PHA must establish utility allowances for manufactured home space rental. For the...

38 CFR 36.4232 - Allowable fees and charges; manufactured home unit.

Code of Federal Regulations, 2011 CFR

2011-07-01

... charges; manufactured home unit. 36.4232 Section 36.4232 Pensions, Bonuses, and Veterans' Relief... Manufactured Homes and Lots, Including Site Preparation Financing Manufactured Home Units § 36.4232 Allowable fees and charges; manufactured home unit. (a) Incident to the origination of a guaranteed loan for the...

38 CFR 36.4232 - Allowable fees and charges; manufactured home unit.

Code of Federal Regulations, 2014 CFR

2014-07-01

... charges; manufactured home unit. 36.4232 Section 36.4232 Pensions, Bonuses, and Veterans' Relief... Manufactured Homes and Lots, Including Site Preparation Financing Manufactured Home Units § 36.4232 Allowable fees and charges; manufactured home unit. (a) Incident to the origination of a guaranteed loan for the...

24 CFR 982.622 - Manufactured home space rental: Rent to owner.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Manufactured home space rental... Special Housing Types Manufactured Home Space Rental § 982.622 Manufactured home space rental: Rent to owner. (a) What is included. (1) Rent to owner for rental of a manufactured home space includes payment...

24 CFR 982.622 - Manufactured home space rental: Rent to owner.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false Manufactured home space rental... Special Housing Types Manufactured Home Space Rental § 982.622 Manufactured home space rental: Rent to owner. (a) What is included. (1) Rent to owner for rental of a manufactured home space includes payment...

24 CFR 982.622 - Manufactured home space rental: Rent to owner.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 4 2014-04-01 2014-04-01 false Manufactured home space rental... Special Housing Types Manufactured Home Space Rental § 982.622 Manufactured home space rental: Rent to owner. (a) What is included. (1) Rent to owner for rental of a manufactured home space includes payment...

24 CFR 201.53 - Disposition of manufactured home loan property.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Disposition of manufactured home... AND OTHER AUTHORITIES TITLE I PROPERTY IMPROVEMENT AND MANUFACTURED HOME LOANS Default Under the Loan Obligation § 201.53 Disposition of manufactured home loan property. Where the lender obtains title to...

24 CFR 201.53 - Disposition of manufactured home loan property.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Disposition of manufactured home... AND OTHER AUTHORITIES TITLE I PROPERTY IMPROVEMENT AND MANUFACTURED HOME LOANS Default Under the Loan Obligation § 201.53 Disposition of manufactured home loan property. Where the lender obtains title to...

24 CFR 201.53 - Disposition of manufactured home loan property.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 2 2013-04-01 2013-04-01 false Disposition of manufactured home... AND OTHER AUTHORITIES TITLE I PROPERTY IMPROVEMENT AND MANUFACTURED HOME LOANS Default Under the Loan Obligation § 201.53 Disposition of manufactured home loan property. Where the lender obtains title to...

16 CFR 1508.10 - Recordkeeping.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Recordkeeping. 1508.10 Section 1508.10 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION FEDERAL HAZARDOUS SUBSTANCES ACT REGULATIONS REQUIREMENTS FOR FULL-SIZE BABY CRIBS § 1508.10 Recordkeeping. A manufacturer or importer of cribs shall keep...

24 CFR 3288.215 - Effect on other manufactured home program requirements.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 5 2010-04-01 2010-04-01 false Effect on other manufactured home... COMMISSIONER, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT MANUFACTURED HOME DISPUTE RESOLUTION PROGRAM State Dispute Resolution Programs in Non-HUD Administered States § 3288.215 Effect on other manufactured home...

24 CFR 3288.215 - Effect on other manufactured home program requirements.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 5 2013-04-01 2013-04-01 false Effect on other manufactured home... COMMISSIONER, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT MANUFACTURED HOME DISPUTE RESOLUTION PROGRAM State Dispute Resolution Programs in Non-HUD Administered States § 3288.215 Effect on other manufactured home...

24 CFR 3288.215 - Effect on other manufactured home program requirements.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 5 2011-04-01 2011-04-01 false Effect on other manufactured home... COMMISSIONER, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT MANUFACTURED HOME DISPUTE RESOLUTION PROGRAM State Dispute Resolution Programs in Non-HUD Administered States § 3288.215 Effect on other manufactured home...

77 FR 65666 - Correction: Proposed Information Collection; Comment Request; Manufacturers' Unfilled Orders Survey

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-30

... DEPARTMENT OF COMMERCE U.S. Census Bureau Correction: Proposed Information Collection; Comment Request; Manufacturers' Unfilled Orders Survey AGENCY: U.S. Census Bureau, Commerce. ACTION: Correction. SUMMARY: On October 16, 2012, a notice was published in the Federal Register (77 FR 63288) on the proposed...

10. BOILER #16 (BUILDING L8) TO LEFT, L.P. AND H.P. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

10. BOILER #16 (BUILDING L8) TO LEFT, L.P. AND H.P. BOILER ROOMS (BUILDINGS L4 AND L2) TO RIGHT, AND STEPHENS SUBSTATION (BUILDING L6) IN BACKGROUND, FROM THE ROOF OF THE POWERHOUSE EXTENSION (BUILDING L5) - Portland General Electric Company, Station "L", 1841 Southeast Water Street, Portland, Multnomah County, OR

Enhancement of Cd phytoextraction by two Amaranthus species with endophytic Rahnella sp. JN27.

PubMed

Yuan, Ming; He, Huaidong; Xiao, Li; Zhong, Ting; Liu, Hui; Li, Shubin; Deng, Peiyan; Ye, Zhihong; Jing, Yuanxiao

2014-05-01

Microbe-assisted phytoextraction shows a potential for the remediation of metal-contaminated soils. The aim of this study was to isolate, characterize, and evaluate the potential of endophytic bacteria in improving plant growth and metal uptake by Cd-hyperaccumulators-Amaranthus hypochondriacus and Amaranthus mangostanus. An endophytic bacterial strain JN27 isolated from roots of Zea mays displayed high tolerance and mobilization to Cd, and was identified as Rahnella sp. based on 16S rDNA sequencing. The strain also exhibited multiple plant growth beneficial features including the production of indole-3-acetic acid, siderophore, 1-aminocyclopropane-1-carboxylic acid deaminase and solubilization of insoluble phosphate. Subsequently, a pot trial was performed to elucidate the effects of inoculation with JN27 on plant growth and Cd uptake by A. hypochondriacus, A. mangostanus, Solanum nigrum and Z. mays grown in soils with different levels of Cd (25, 50, 100 mg Cd kg(-1)). The results revealed that inoculation with JN27 significantly increased the biomasses of all the tested plants and the Cd concentrations of all the tested plants except Z. mays in both above-ground and root tissues. Moreover, strain JN27 could successfully re-colonized in rhizosphere soils of all the tested plants and root interior of A. hypochondriacus and Z. mays. The present results indicated that the symbiont of A. hypochondriacus (or A. mangostanus) and strain JN27 can effectively improve the Cd uptake by plants and would be a new strategy in microbe-assisted phytoextraction for metal-contaminated soils. Copyright © 2013 Elsevier Ltd. All rights reserved.

78 FR 1779 - Disclosures Regarding Energy Consumption and Water Use of Certain Home Appliances and Other...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-09

... looking at EnergyGuide labels, manufacturer advertising, or DOE certification data.\\43\\ \\42\\ 77 FR at... List of Subjects in 16 CFR Part 305 Advertising, Energy conservation, Household appliances, Labeling...

Northwest Energy Efficient Manufactured Housing Program: High Performance Manufactured Home Prototyping and Construction Development

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hewes, Tom; Peeks, Brady

2013-11-01

The Building America Partnership for Improved Residential Construction, the Bonneville Power Administration (BPA), and Northwest Energy Works (NEW), the current Northwest Energy Efficient Manufactured Housing Program (NEEM) administrator, have been collaborating to conduct research on new specifications that would improve on the energy requirements of a NEEM home. In its role as administrator, NEW administers the technical specs, performs research and engineering analysis, implements ongoing construction quality management procedures, and maintains a central database with home tracking. This project prototyped and assessed the performances of cost-effective high performance building assemblies and mechanical systems that are not commonly deployed in themore » manufacturing setting. The package of measures is able to reduce energy used for space conditioning, water heating and lighting by 50% over typical manufactured homes produced in the northwest.« less

24 CFR 201.21 - Manufactured home loan eligibility.

Code of Federal Regulations, 2010 CFR

2010-04-01

... evidenced by a label or tag affixed to the manufactured home in accordance with 24 CFR 3280.8. (2) During... in accordance with the current edition of HUD's Permanent Foundations Guide for Manufactured Housing... electrical systems to assure that they are fully operational. (d) Manufacturer's warranty requirements. (1...

Northwest Energy Efficient Manufactured Housing Program: High Performance Manufactured Home Prototyping and Construction Development

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hewes, Tom; Peeks, Brady

2013-11-01

The Building America Partnership for Improved Residential Construction, the Bonneville Power Administration (BPA), and Northwest Energy Works (NEW), the current Northwest Energy Efficient Manufactured Housing Program (NEEM) administrator, have been collaborating to conduct research on new specifications that would improve on the energy requirements of a NEEM home. In its role as administrator, NEW administers the technical specs, performs research and engineering analysis, implements ongoing construction quality management procedures, and maintains a central database with home tracking. This project prototyped and assessed the performances of cost-effective high performance building assemblies and mechanical systems that are not commonly deployed in themore » manufacturing setting. The package of measures is able to reduce energy used for space conditioning, water heating and lighting by 50 percent over typical manufactured homes produced in the northwest.« less

16 CFR 307.10 - Cooperative advertising.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Cooperative advertising. 307.10 Section 307... REGULATIONS UNDER THE COMPREHENSIVE SMOKELESS TOBACCO HEALTH EDUCATION ACT OF 1986 Advertising Disclosures § 307.10 Cooperative advertising. The Act prohibits any manufacturer, packager, or importer of smokeless...

Computers in Manufacturing.

ERIC Educational Resources Information Center

Hudson, C. A.

1982-01-01

Advances in factory computerization (computer-aided design and computer-aided manufacturing) are reviewed, including discussions of robotics, human factors engineering, and the sociological impact of automation. (JN)

24 CFR 3285.102 - Installation of manufactured homes in flood hazard areas.

Code of Federal Regulations, 2010 CFR

2010-04-01

... HOUSING COMMISSIONER, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT MODEL MANUFACTURED HOME INSTALLATION STANDARDS Pre-Installation Considerations § 3285.102 Installation of manufactured homes in flood hazard...

24 CFR 3285.102 - Installation of manufactured homes in flood hazard areas.

Code of Federal Regulations, 2011 CFR

2011-04-01

... HOUSING COMMISSIONER, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT MODEL MANUFACTURED HOME INSTALLATION STANDARDS Pre-Installation Considerations § 3285.102 Installation of manufactured homes in flood hazard...

24 CFR 3285.102 - Installation of manufactured homes in flood hazard areas.

Code of Federal Regulations, 2012 CFR

2012-04-01

... HOUSING COMMISSIONER, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT MODEL MANUFACTURED HOME INSTALLATION STANDARDS Pre-Installation Considerations § 3285.102 Installation of manufactured homes in flood hazard...

12 CFR Appendix IV to Part 27 - Home Loan Data Submission

Code of Federal Regulations, 2014 CFR

2014-01-01

... 12 Banks and Banking 1 2014-01-01 2014-01-01 false Home Loan Data Submission IV Appendix IV to Part 27 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY FAIR HOUSING HOME LOAN DATA SYSTEM Pt. 27, App. IV Appendix IV to Part 27—Home Loan Data Submission ER21JN94.003 ER21JN94...

12 CFR Appendix IV to Part 27 - Home Loan Data Submission

Code of Federal Regulations, 2013 CFR

2013-01-01

... 12 Banks and Banking 1 2013-01-01 2013-01-01 false Home Loan Data Submission IV Appendix IV to Part 27 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY FAIR HOUSING HOME LOAN DATA SYSTEM Pt. 27, App. IV Appendix IV to Part 27—Home Loan Data Submission ER21JN94.003 ER21JN94...

12 CFR Appendix IV to Part 27 - Home Loan Data Submission

Code of Federal Regulations, 2011 CFR

2011-01-01

... 12 Banks and Banking 1 2011-01-01 2011-01-01 false Home Loan Data Submission IV Appendix IV to Part 27 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY FAIR HOUSING HOME LOAN DATA SYSTEM Pt. 27, App. IV Appendix IV to Part 27—Home Loan Data Submission ER21JN94.003 ER21JN94...

12 CFR Appendix IV to Part 27 - Home Loan Data Submission

Code of Federal Regulations, 2012 CFR

2012-01-01

... 12 Banks and Banking 1 2012-01-01 2012-01-01 false Home Loan Data Submission IV Appendix IV to Part 27 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY FAIR HOUSING HOME LOAN DATA SYSTEM Pt. 27, App. IV Appendix IV to Part 27—Home Loan Data Submission ER21JN94.003 ER21JN94...

12 CFR Appendix IV to Part 27 - Home Loan Data Submission

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Home Loan Data Submission IV Appendix IV to Part 27 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY FAIR HOUSING HOME LOAN DATA SYSTEM Pt. 27, App. IV Appendix IV to Part 27—Home Loan Data Submission ER21JN94.003 ER21JN94...

24 CFR 3282.413 - Replacement or repurchase of manufactured home from purchaser.

Code of Federal Regulations, 2010 CFR

2010-04-01

... home be replaced by the manufacturer with a manufactured home substantially equal in size, equipment... to the attention of the Secretary. (c) In those situations where, under contract or other applicable...

Job Prospects for Manufacturing Engineers.

ERIC Educational Resources Information Center

Basta, Nicholas

1985-01-01

Coming from a variety of disciplines, manufacturing engineers are keys to industry's efforts to modernize, with demand exceeding supply. The newest and fastest-growing areas include machine vision, composite materials, and manufacturing automation protocols, each of which is briefly discussed. (JN)

77 FR 6536 - Approval for Manufacturing Authority; Foreign-Trade Zone 177; Best Chair, Inc., d/b/a Best Home...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-08

... manufacturing authority on behalf of Best Chair, Inc., d/ b/a Best Home Furnishings, Inc., within FTZ 177 in... application for manufacturing authority under zone procedures within FTZ 177 on behalf of Best Chair, Inc., d... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [Order No. 1807] Approval for Manufacturing...

75 FR 27576 - J.N. “Ding” Darling National Wildlife Refuge, Lee County, FL

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-17

... DEPARTMENT OF THE INTERIOR Fish and Wildlife Service [FWS-R4-R-2010-N052; 40136-1265-0000-S3] J.N. ``Ding'' Darling National Wildlife Refuge, Lee County, FL AGENCY: Fish and Wildlife Service, Interior... variety of species in a highly developed landscape. The city of Sanibel, Lee County, Sanibel-Captiva...

75 FR 11228 - Surety Companies Acceptable on Federal Bonds: Pennsylvania Manufacturers Indemnity Company

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-10

... of the Treasury, Financial Management Service, Financial Accounting and Services Division, Surety... L. Cooper, Director, Financial Accounting and Services Division. [FR Doc. 2010-4938 Filed 3-9-10; 8...: Pennsylvania Manufacturers Indemnity Company AGENCY: Financial Management Service, Fiscal Service, Department...

78 FR 49547 - Manufacturer of Controlled Substances, Notice of Registration, Rhodes Technologies

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-14

..., Notice of Registration, Rhodes Technologies By Notice dated April 10, 2013, and published in the Federal Register on April 19, 2013, 78 FR 23596, Rhodes Technologies, 498 Washington Street, Coventry, Rhode Island... registration of Rhodes Technologies to manufacture the listed basic classes of controlled substances is...

A genome-scale metabolic reconstruction of Pseudomonas putida KT2440: iJN746 as a cell factory.

PubMed

Nogales, Juan; Palsson, Bernhard Ø; Thiele, Ines

2008-09-16

Pseudomonas putida is the best studied pollutant degradative bacteria and is harnessed by industrial biotechnology to synthesize fine chemicals. Since the publication of P. putida KT2440's genome, some in silico analyses of its metabolic and biotechnology capacities have been published. However, global understanding of the capabilities of P. putida KT2440 requires the construction of a metabolic model that enables the integration of classical experimental data along with genomic and high-throughput data. The constraint-based reconstruction and analysis (COBRA) approach has been successfully used to build and analyze in silico genome-scale metabolic reconstructions. We present a genome-scale reconstruction of P. putida KT2440's metabolism, iJN746, which was constructed based on genomic, biochemical, and physiological information. This manually-curated reconstruction accounts for 746 genes, 950 reactions, and 911 metabolites. iJN746 captures biotechnologically relevant pathways, including polyhydroxyalkanoate synthesis and catabolic pathways of aromatic compounds (e.g., toluene, benzoate, phenylacetate, nicotinate), not described in other metabolic reconstructions or biochemical databases. The predictive potential of iJN746 was validated using experimental data including growth performance and gene deletion studies. Furthermore, in silico growth on toluene was found to be oxygen-limited, suggesting the existence of oxygen-efficient pathways not yet annotated in P. putida's genome. Moreover, we evaluated the production efficiency of polyhydroxyalkanoates from various carbon sources and found fatty acids as the most prominent candidates, as expected. Here we presented the first genome-scale reconstruction of P. putida, a biotechnologically interesting all-surrounder. Taken together, this work illustrates the utility of iJN746 as i) a knowledge-base, ii) a discovery tool, and iii) an engineering platform to explore P. putida's potential in bioremediation and bioplastic

Genetics Home Reference: 16p11.2 duplication

MedlinePlus

... Marshall CR, Scherer SW. Phenotypic spectrum associated with de novo and inherited deletions and duplications at 16p11. ... ND, Thorleifsson G, Belfiore M, Bouquillon S, Campion D, de Leeuw N, de Vries BB, Esko T, Fernandez ...

16 CFR 1512.10 - Requirements for tires.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Requirements for tires. 1512.10 Section 1512... REGULATIONS REQUIREMENTS FOR BICYCLES Regulations § 1512.10 Requirements for tires. The manufacturer's recommended inflation pressure shall be molded into or onto the sidewall of the tire in lettering no less than...

Genetics Home Reference: 16p11.2 deletion syndrome

MedlinePlus

... Schuurs-Hoeijmakers JH, van Haeringen A, Fransen van de Putte DE, Anderlid BM, Lundin J, Lapunzina P, Pérez Jurado ... Marshall CR, Scherer SW. Phenotypic spectrum associated with de novo and inherited deletions and duplications at 16p11. ...

16 CFR 700.2 - Date of manufacture.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Date of manufacture. 700.2 Section 700.2... MAGNUSON-MOSS WARRANTY ACT INTERPRETATIONS OF MAGNUSON-MOSS WARRANTY ACT § 700.2 Date of manufacture... after July 4, 1975. When a consumer purchases repair of a consumer product the date of manufacture of...

Atmospheric Retrievals of HAT-P-16b and WASP-11b/HAT-P-10b

NASA Astrophysics Data System (ADS)

McIntyre, Kathleen; Harrington, Joseph; Challener, Ryan; Lenius, Maria; Hartman, Joel D.; Bakos, Gaspar A.; Blecic, Jasmina; Cubillos, Patricio E.; Cameron, Andrew

2018-01-01

We report Bayesian atmospheric retrievals performed on the exoplanets HAT-P-16b and WASP-11b/HAT-P-10b. HAT-P-16b is a hot (equilibrium temperature 1626 ± 40 K, assuming zero Bond albedo and efficient energy redistribution), 4.19 ± 0.09 Jupiter-mass exoplanet orbiting an F8 star every 2.775960 ± 0.000003 days (Buchhave et al 2010). WASP-11b/HAT-P-10b is a cooler (1020 ± 17 K), 0.487 ± 0.018 Jupiter-mass exoplanet orbiting a K3 star every 3.7224747 ± 0.0000065 days (Bakos et al. 2009, co-discovered by West et al. 2008). We observed secondary eclipses of both planets using the 3.6 μm and 4.5 μm channels of the Spitzer Space Telescope's Infrared Array Camera (program ID 60003). We applied our Photometry for Orbits, Eclipses, and Transits (POET) code to produce normalized eclipse light curves, and our Bayesian Atmospheric Radiative Transfer (BART) code to constrain the temperature-pressure profiles and atmospheric molecular abundances of the two planets. Spitzer is operated by the Jet Propulsion Laboratory, California Institute of Technology, under a contract with NASA. This work was supported by NASA Planetary Atmospheres grant NNX12AI69G and NASA Astrophysics Data Analysis Program grant NNX13AF38G.

16 CFR 1207.10 - Handling, storage, and marking.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 16 Commercial Practices 2 2011-01-01 2011-01-01 false Handling, storage, and marking. 1207.10... REGULATIONS SAFETY STANDARD FOR SWIMMING POOL SLIDES § 1207.10 Handling, storage, and marking. (a) Marking... identification of the manufacturer. (b) Shipping, handling, and storage. The slide shall be designed, constructed...

16 CFR 1207.10 - Handling, storage, and marking.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 16 Commercial Practices 2 2014-01-01 2014-01-01 false Handling, storage, and marking. 1207.10... REGULATIONS SAFETY STANDARD FOR SWIMMING POOL SLIDES § 1207.10 Handling, storage, and marking. (a) Marking... identification of the manufacturer. (b) Shipping, handling, and storage. The slide shall be designed, constructed...

16 CFR 1207.10 - Handling, storage, and marking.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 16 Commercial Practices 2 2012-01-01 2012-01-01 false Handling, storage, and marking. 1207.10... REGULATIONS SAFETY STANDARD FOR SWIMMING POOL SLIDES § 1207.10 Handling, storage, and marking. (a) Marking... identification of the manufacturer. (b) Shipping, handling, and storage. The slide shall be designed, constructed...

16 CFR 1207.10 - Handling, storage, and marking.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Handling, storage, and marking. 1207.10... REGULATIONS SAFETY STANDARD FOR SWIMMING POOL SLIDES § 1207.10 Handling, storage, and marking. (a) Marking... identification of the manufacturer. (b) Shipping, handling, and storage. The slide shall be designed, constructed...

Field Evaluation of Advances in Energy-Efficiency Practices for Manufactured Homes

DOE Office of Scientific and Technical Information (OSTI.GOV)

E. Levy; Dentz, J.; Ansanelli, E.

2016-03-01

Through field-testing and analysis, this project evaluated whole-building approaches and estimated the relative contributions of select technologies toward reducing energy use related to space conditioning in new manufactured homes. Three lab houses of varying designs were built and tested side-by-side under controlled conditions in Russellville, Alabama. The tests provided a valuable indicator of how changes in the construction of manufactured homes can contribute to significant reductions in energy use.

Change in mineral weathering behaviors of a bacterium Chitinophaga jiangningensis JN53 under different nutrition conditions.

PubMed

Cheng, Cheng; Wang, Qi; He, Linyan; Sheng, Xiafang

2017-04-01

Bacteria play important roles in mineral weathering and soil formation. However, little is known about the nutrition-related changes in mineral weathering potential and pattern of bacteria. In this study, mineral weathering behaviors of a novel mineral-weathering bacterium Chitinophaga jiangningensis JN53 were characterized in the presence of three contrasting biotite or potassium feldspar-added media. C. jiangningensis JN53 increased more Fe release from the minerals in the M-BHm (nutrition-poor medium) than in the SSKM (nutrition-rich medium) and BHm (nutrition-moderate medium), while C. jiangningensis JN53 released more Al from the minerals and Si from biotite in the SSKM. Similar Si release from potassium feldspar by C. jiangningensis JN53 was observed in the SSKM, BHm, and M-BHm. K releasing ability of C. jiangningensis JN53 was significantly higher in the biotite-added M-BHm. Highest and lowest growth of C. jiangningensis JN53 was observed in the SSKM and M-BHm, respectively. In the presence of the minerals, C. jiangningensis JN53 mainly produced gluconic acid in the SSKM and acetic acid in the BHm and M-BHm. C. jiangningensis JN53 also produced large amount of succinic acid in the biotite-added SSKM and oxalic acid in the potassium feldspar-added M-BHm. The results showed the growth, production of organic acids, and mineral weathering ability of C. jiangningensis JN53 in the three contrasting nutrition conditions. The results also suggested the change in the mineral weathering behaviors of C. jiangningensis JN53 under different levels of nutrition conditions. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Net Zero Energy Manufactured Homes May Be on their Way

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gilbride, Theresa L.; Dentz, Jordan

This article, published in Home Energy Magazine, describes a research project sponsored by the U.S. Department of Energy's Building America program, to construct and test the first manufactured home in the United States built to the performance criteria of DOE's Zero Energy Ready Home program. A 15-month study was conducted to compare the real-world performance of the DOE Zero Energy Ready home and two other manufactured homes - one built to just above industry standard construction and one built to the ENERGY STAR Certified Home criteria. The homes were built by Clayton Homes' Southern Energy Division and testing was sponsoredmore » by DOE's Building America program and conducted by the Levy Partnership. The DOE ZERH had increased initial construction costs of $6,607 compared to the standard home versus $4,340 for the ENERGY STAR home but reduced energy bills by $50 per month compared to a $33/month savings for the ENERGY STAR home, and monthly savings will continue for the life of the home. Savings were especially noticeable in the summer in this cooling-dominated test location. The DOE ZERH cut cooling costs in half compared to the ENERGY STAR home which performed only slightly better than the standard home in summer, while winter savings between the two advanced homes were more similar. Two technology advances were tested in the DOE ZERH home. Instead of the typical ducted heating and cooling system, the DOE ZERH home was equipped with a ductless heat pump; to condition the bedroom, holes were cut into bedroom walls and small fans were installed to pull air into those rooms, while door undercuts and transfer grilles provide return paths. A novel dense-pack attic insulation was also implemented.« less

21 CFR 1140.16 - Conditions of manufacture, sale, and distribution.

Code of Federal Regulations, 2010 CFR

2010-04-01

... SERVICES (CONTINUED) TOBACCO PRODUCTS CIGARETTES AND SMOKELESS TOBACCO; Eff. 6-22-10 Prohibition of Sale and Distribution to Persons Younger Than 18 Years of Age § 1140.16 Conditions of manufacture, sale... where the retailer ensures that no person younger than 18 years of age is present, or permitted to enter...

16 CFR § 1207.10 - Handling, storage, and marking.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 16 Commercial Practices 2 2013-01-01 2013-01-01 false Handling, storage, and marking. § 1207.10... REGULATIONS SAFETY STANDARD FOR SWIMMING POOL SLIDES § 1207.10 Handling, storage, and marking. (a) Marking... identification of the manufacturer. (b) Shipping, handling, and storage. The slide shall be designed, constructed...

38 CFR 36.4225 - Authority to close manufactured home loans on the automatic basis.

Code of Federal Regulations, 2014 CFR

2014-07-01

... on a normal accounting or business cycle. The lender's latest financial statements (profit and loss... manufactured home loans on the automatic basis. 36.4225 Section 36.4225 Pensions, Bonuses, and Veterans' Relief... manufactured home loans on the automatic basis. (a) Supervised lenders of the classes described in 38 U.S.C...

38 CFR 36.4225 - Authority to close manufactured home loans on the automatic basis.

Code of Federal Regulations, 2011 CFR

2011-07-01

... on a normal accounting or business cycle. The lender's latest financial statements (profit and loss... manufactured home loans on the automatic basis. 36.4225 Section 36.4225 Pensions, Bonuses, and Veterans' Relief... manufactured home loans on the automatic basis. (a) Supervised lenders of the classes described in 38 U.S.C...

38 CFR 36.4225 - Authority to close manufactured home loans on the automatic basis.

Code of Federal Regulations, 2013 CFR

2013-07-01

... on a normal accounting or business cycle. The lender's latest financial statements (profit and loss... manufactured home loans on the automatic basis. 36.4225 Section 36.4225 Pensions, Bonuses, and Veterans' Relief... manufactured home loans on the automatic basis. (a) Supervised lenders of the classes described in 38 U.S.C...

38 CFR 36.4225 - Authority to close manufactured home loans on the automatic basis.

Code of Federal Regulations, 2012 CFR

2012-07-01

... on a normal accounting or business cycle. The lender's latest financial statements (profit and loss... manufactured home loans on the automatic basis. 36.4225 Section 36.4225 Pensions, Bonuses, and Veterans' Relief... manufactured home loans on the automatic basis. (a) Supervised lenders of the classes described in 38 U.S.C...

16 CFR 460.2 - What is home insulation.

Code of Federal Regulations, 2012 CFR

2012-01-01

... INSULATION § 460.2 What is home insulation. Insulation is any material mainly used to slow down heat flow. It... 16 Commercial Practices 1 2012-01-01 2012-01-01 false What is home insulation. 460.2 Section 460.2..., semirigid, flexible, or loose-fill form. Home insulation is for use in old or new homes, condominiums...

16 CFR 460.2 - What is home insulation.

Code of Federal Regulations, 2013 CFR

2013-01-01

... INSULATION § 460.2 What is home insulation. Insulation is any material mainly used to slow down heat flow. It... 16 Commercial Practices 1 2013-01-01 2013-01-01 false What is home insulation. 460.2 Section 460.2..., semirigid, flexible, or loose-fill form. Home insulation is for use in old or new homes, condominiums...

16 CFR 460.2 - What is home insulation.

Code of Federal Regulations, 2010 CFR

2010-01-01

... INSULATION § 460.2 What is home insulation. Insulation is any material mainly used to slow down heat flow. It... 16 Commercial Practices 1 2010-01-01 2010-01-01 false What is home insulation. 460.2 Section 460.2..., semirigid, flexible, or loose-fill form. Home insulation is for use in old or new homes, condominiums...

16 CFR 460.2 - What is home insulation.

Code of Federal Regulations, 2014 CFR

2014-01-01

... INSULATION § 460.2 What is home insulation. Insulation is any material mainly used to slow down heat flow. It... 16 Commercial Practices 1 2014-01-01 2014-01-01 false What is home insulation. 460.2 Section 460.2..., semirigid, flexible, or loose-fill form. Home insulation is for use in old or new homes, condominiums...

16 CFR 460.2 - What is home insulation.

Code of Federal Regulations, 2011 CFR

2011-01-01

... INSULATION § 460.2 What is home insulation. Insulation is any material mainly used to slow down heat flow. It... 16 Commercial Practices 1 2011-01-01 2011-01-01 false What is home insulation. 460.2 Section 460.2..., semirigid, flexible, or loose-fill form. Home insulation is for use in old or new homes, condominiums...

16 CFR 460.8 - R-value tolerances.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 16 Commercial Practices 1 2010-01-01 2010-01-01 false R-value tolerances. 460.8 Section 460.8... INSULATION § 460.8 R-value tolerances. If you are a manufacturer of home insulation, no individual specimen of the insulation you sell can have an R-value more than 10% below the R-value shown in a label, fact...

16 CFR 1204.5 - Manufacturer's instructions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Manufacturer's instructions. 1204.5 Section 1204.5 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS SAFETY STANDARD FOR OMNIDIRECTIONAL CITIZENS BAND BASE STATION ANTENNAS The Standard § 1204.5...

Manufactured Homes as Affordable Housing in Rural Areas. Rural Information Center Publication Series, No. 5.

ERIC Educational Resources Information Center

Czerniak, Robert, Comp.

This bibliography includes citations of approximately 60 books and articles pertaining to manufactured housing or "mobile homes," an important segment of the national housing industry. The availability of manufactured homes for low and moderate income groups is significant in light of skyrocketing new-housing costs. The South leads the nation with…

38 CFR 36.4251 - Loans to finance the purchase of manufactured homes and the cost of necessary site preparation.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2014-07-01 2014-07-01 false Loans to finance the purchase of manufactured homes and the cost of necessary site preparation. 36.4251 Section 36.4251 Pensions... Manufactured Home Lot Loans § 36.4251 Loans to finance the purchase of manufactured homes and the cost of...

38 CFR 36.4251 - Loans to finance the purchase of manufactured homes and the cost of necessary site preparation.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2011-07-01 2011-07-01 false Loans to finance the purchase of manufactured homes and the cost of necessary site preparation. 36.4251 Section 36.4251 Pensions... Manufactured Home Lot Loans § 36.4251 Loans to finance the purchase of manufactured homes and the cost of...

38 CFR 36.4251 - Loans to finance the purchase of manufactured homes and the cost of necessary site preparation.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2012-07-01 2012-07-01 false Loans to finance the purchase of manufactured homes and the cost of necessary site preparation. 36.4251 Section 36.4251 Pensions... Manufactured Home Lot Loans § 36.4251 Loans to finance the purchase of manufactured homes and the cost of...

38 CFR 36.4251 - Loans to finance the purchase of manufactured homes and the cost of necessary site preparation.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2013-07-01 2013-07-01 false Loans to finance the purchase of manufactured homes and the cost of necessary site preparation. 36.4251 Section 36.4251 Pensions... Manufactured Home Lot Loans § 36.4251 Loans to finance the purchase of manufactured homes and the cost of...

16 CFR 1102.12 - Manufacturer comments.

Code of Federal Regulations, 2011 CFR

2011-01-01

... PUBLICLY AVAILABLE CONSUMER PRODUCT SAFETY INFORMATION DATABASE (Eff. Jan. 10, 2011) Content Requirements... private labeler in the Database if such manufacturer comment meets the following requirements: (1... that is submitted for publication in the Database. (2) Unique identifier. A manufacturer comment must...

16 CFR 1102.30 - Publication of manufacturer comments.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 16 Commercial Practices 2 2014-01-01 2014-01-01 false Publication of manufacturer comments. 1102... Requirements § 1102.30 Publication of manufacturer comments. Timing. Subject to §§ 1102.12, 1102.24, and 1102... report of harm that meet the minimum requirements set forth in § 1102.12(c). This publication will occur...

The Thermal Flash Protection System, low pass filter JN175666A1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Washington, L.A.

1987-06-01

This report discusses the development of the JN175666A1 Low Pass Filter used in the B1-B Thermal Flash Protection System. It also discusses problems encountered during development of the ceramic capacitors and how they were resolved. Included in this report is a description of the filter, the electrical and environmental tests, why they were performed and data accumulated during the development testing. After completing the evaluation of this device, it is concluded that the JN175666A1 filter is a usable component for the B1-B system.

49 CFR 534.5 - Manufacturers within control relationships.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 6 2011-10-01 2011-10-01 false Manufacturers within control relationships. 534.5... IN THE CONTEXT OF CHANGES IN CORPORATE RELATIONSHIPS § 534.5 Manufacturers within control relationships. Link to an amendment published at 76 FR 57492, Sept. 15, 2011. (a) If a civil penalty arises out...

75 FR 7556 - Energy Efficiency Standards for Manufactured Housing

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-22

... financial considerations and life cycle costs. (4) Statistics associated with HVAC system and equipment type... standards. Provide a system for enforcement in which ``[a]ny manufacturer of manufactured housing that... available for products, systems, equipment, and materials used in the construction of manufactured homes...

78 FR 40434 - Meeting of the Manufacturing Council

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-05

... subcommittees. The subcommittees--Workforce and Public Perception of Manufacturing; Innovation, Research and.... Government and the manufacturing sector. DATES: July 23, 2013, 10:00 a.m.-12:30 p.m. Eastern Daylight Time... comments from members of the public attending the meeting. To accommodate as many speakers as possible, the...

16p11.2–p12.2 duplication syndrome; a genomic condition differentiated from euchromatic variation of 16p11.2

PubMed Central

Barber, John C K; Hall, Victoria; Maloney, Viv K; Huang, Shuwen; Roberts, Angharad M; Brady, Angela F; Foulds, Nicki; Bewes, Beverley; Volleth, Marianne; Liehr, Thomas; Mehnert, Karl; Bateman, Mark; White, Helen

2013-01-01

Chromosome 16 contains multiple copy number variations (CNVs) that predispose to genomic disorders. Here, we differentiate pathogenic duplications of 16p11.2–p12.2 from microscopically similar euchromatic variants of 16p11.2. Patient 1 was a girl of 18 with autism, moderate intellectual disability, behavioural difficulties, dysmorphic features and a 7.71-Mb (megabase pair) duplication (16:21 521 005–29 233 146). Patient 2 had a 7.81-Mb duplication (16:21 382 561–29 191 527), speech delay and obsessional behaviour as a boy and, as an adult, short stature, macrocephaly and mild dysmorphism. The duplications contain 65 coding genes of which Polo-like kinase 1 (PLK1) has the highest likelihood of being haploinsufficient and, by implication, a triplosensitive gene. An additional 1.11-Mb CNV of 10q11.21 in Patient 1 was a possible modifier containing the G-protein-regulated inducer of neurite growth 2 (GPRIN2) gene. In contrast, the euchromatic variants in Patients 3 and 4 were amplifications from a 945-kb region containing non-functional immunoglobulin heavy chain (IGHV), hect domain pseudogene (HERC2P4) and TP53-inducible target gene 3 (TP53TG3) loci in proximal 16p11.2 (16:31 953 353–32 898 635). Paralogous pyrosequencing gave a total copy number of 3–8 in controls and 8 to >10 in Patients 3 and 4. The 16p11.2–p12.2 duplication syndrome is a recurrent genomic disorder with a variable phenotype including developmental delay, dysmorphic features, mild to severe intellectual disability, autism, obsessive or stereotyped behaviour, short stature and anomalies of the hands and fingers. It is important to differentiate pathogenic 16p11.2–p12.2 duplications from harmless, microscopically similar euchromatic variants of proximal 16p11.2, especially at prenatal diagnosis. PMID:22828807

Activation of neurokinin-1 receptor by substance P inhibits melanogenesis in B16-F10 melanoma cells.

PubMed

Ping, Fengfeng; Shang, Jing; Zhou, Jia; Song, Jing; Zhang, Luyong

2012-12-01

Skin pigmentation plays a number of valuable roles and its regulation is a complex process that is controlled by different factors. Substance P (SP) regulates many biological functions, including neurogenic inflammation, pain, and stress. However, to date, the regulatory role of SP in the control of melanogenesis has not been elucidated. The present study was designed to investigate the effects of SP on melanogenesis and to elucidate its underlying mechanism(s). After treatment for 48 h in mouse B16-F10 melanoma cells, SP (1 and 10nM) significantly down-regulated tyrosinase activity and melanin content. Importantly, western blot analysis revealed the presence of neurokinin-1 receptor (NK-1 R) in B16-F10 cells and the activation of it after SP treatment. It was also found that preincubation with NK-1 receptor antagonist Spantide I could partially reversed SP-induced down-regulations of tyrosinase activity, melanin content and the expression of tyrosinase and tyrosinase-related protein 1. Furthermore, SP could remarkably inhibit the expressions of microphtalmia-associated transcription factor (MITF) and p-p38 MAPK and stimulated p-p70 S6K1. These effects could also be partially reversed by the pretreatment with Spantide I. These results collectively suggested that SP inhibited melanogenesis in B16-F10 cells, which might be attributed to the fact that SP induces the activation of NK-1 receptor, stimulates the phosphorylation of p70 S6K1 and inhibits that of p38 MAPK, decreases the tyrosinase and tyrosinase-related protein 1 expression through MITF, finally resulting in the suppression of melanogenesis. These observations in vitro indicated that the regulation of the SP/NK-1 receptor system might be a useful novel management for skin pigmentation. Copyright © 2012 Elsevier Ltd. All rights reserved.

Differential Effects of Methoxylated p-Coumaric Acids on Melanoma in B16/F10 Cells

PubMed Central

Yoon, Hoon Seok; Lee, Nam-Ho; Hyun, Chang-Gu; Shin, Dong-Bum

2015-01-01

As an approach to search for chemopreventive agents, we tested p-coumaric acid, 3-methoxy-p-coumaric acid (ferulic acid), and 3,5-dimethoxy-p-coumaric acid (sinapic acid) in B16/F10 melanoma cells. Intracellular melanin contents were determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide assay and cytotoxicity of the compounds were examined by lactate dehydrogenase (LDH) release. p-Coumaric acid showed inhibitory effect on melanogenesis, but ferulic acid increased melanin content, and sinapic acid had almost no effect on melanogenesis. Treatment with ferulic acid resulted in a 2 to 3 fold elevation in the production of melanin. Correlatively, cell viability decreased in a dose-dependent manner when treated with ferulic acid. However, ferulic acid did not affect the LDH release from the cells. Treatment with sinapic acid resulted in a 50~60% elevation in the release of LDH when treated with a 200 μg/mL concentration and showed neither cytostasis nor increase of melanin synthesis in a dose-dependent manner. Taken together, p-coumaric acid inhibits melanogenesis, ferulic acid induces melanogenesis, and sinapic acid exerts cytotoxic effects in B16/F10 murine melanoma cells. The results indicate that the addition of methoxy groups to p-coumaric acid shows the melanogenic or cytotoxic effects in melanoma cells compared to the original compound. Therefore, this study suggests the possibility that methoxylated p-coumaric acid, ferulic acid can be used as a chemopreventive agent. PMID:25866753

76 FR 8777 - Manufacturer of Controlled Substances; Notice of Registration

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-15

... DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Registration By Notice dated October 19, 2010, and published in the Federal Register on October 26, 2010, 75 FR 65659, Cedarburg Pharmaceuticals, Inc., 870 Badger Circle, Grafton, Wisconsin 53024...

75 FR 32506 - Manufacturer of Controlled Substances; Notice of Registration

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-08

... DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Registration By Notice dated December 1, 2009, and published in the Federal Register on December 11, 2009 (74 FR 65789), Cedarburg Pharmaceuticals, Inc., 870 Badger Circle, Grafton, Wisconsin...

Hyperactivity and male-specific sleep deficits in the 16p11.2 deletion mouse model of autism.

PubMed

Angelakos, Christopher C; Watson, Adam J; O'Brien, W Timothy; Krainock, Kyle S; Nickl-Jockschat, Thomas; Abel, Ted

2017-04-01

Sleep disturbances and hyperactivity are prevalent in several neurodevelopmental disorders, including autism spectrum disorders (ASDs) and attention deficit-hyperactivity disorder (ADHD). Evidence from genome-wide association studies indicates that chromosomal copy number variations (CNVs) are associated with increased prevalence of these neurodevelopmental disorders. In particular, CNVs in chromosomal region 16p11.2 profoundly increase the risk for ASD and ADHD, disorders that are more common in males than females. We hypothesized that mice hemizygous for the 16p11.2 deletion (16p11.2 del/+) would exhibit sex-specific sleep and activity alterations. To test this hypothesis, we recorded activity patterns using infrared beam breaks in the home-cage of adult male and female 16p11.2 del/+ and wildtype (WT) littermates. In comparison to controls, we found that both male and female 16p11.2 del/+ mice exhibited robust home-cage hyperactivity. In additional experiments, sleep was assessed by polysomnography over a 24-hr period. 16p11.2 del/+ male, but not female mice, exhibited significantly more time awake and significantly less time in non-rapid-eye-movement (NREM) sleep during the 24-hr period than wildtype littermates. Analysis of bouts of sleep and wakefulness revealed that 16p11.2 del/+ males, but not females, spent a significantly greater proportion of wake time in long bouts of consolidated wakefulness (greater than 42 min in duration) compared to controls. These changes in hyperactivity, wake time, and wake time distribution in the males resemble sleep disturbances observed in human ASD and ADHD patients, suggesting that the 16p11.2 del/+ mouse model may be a useful genetic model for studying sleep and activity problems in human neurodevelopmental disorders. Autism Res 2016. © 2016 International Society for Autism Research, Wiley Periodicals, Inc. Autism Res 2017, 10: 572-584. © 2016 International Society for Autism Research, Wiley Periodicals, Inc. © 2016

76 FR 53961 - Manufacturer of Controlled Substances; Notice of Registration

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-30

... DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Registration By Notice dated April 15, 2011, and published in the Federal Register on April 27, 2011, 76 FR 23627, Cedarburg Pharmaceuticals, Inc., 870 Badger Circle, Grafton, Wisconsin 53024, made...

76 FR 14690 - Manufacturer of Controlled Substances; Notice of Registration

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-17

... December 3, 2010, (75 FR 75498), Agilent Technologies, 25200 Commercentre Drive, Lake Forest, California... determined that the registration of Agilent Technologies to manufacture the listed basic classes of... Technologies to ensure that the company's registration is consistent with the public interest. The...

A New Enhanced Engineering Programme for Manufacturing Industries.

ERIC Educational Resources Information Center

Clark, C.; And Others

1985-01-01

Special Engineering Programmes (SEPs) were established in Great Britain to attract highly able students into engineering and to provide education/training to meet the needs of manufacturing industries. SEP philosophy and objectives, program structure, student selection, course assessment, and other areas are discussed. (JN)

40 CFR 439.10 - Applicability.

Code of Federal Regulations, 2010 CFR

2010-07-01

... PHARMACEUTICAL MANUFACTURING POINT SOURCE CATEGORY Fermentation Products § 439.10 Applicability. This subpart applies to discharges of process wastewater resulting from the manufacture of pharmaceutical products by fermentation. [63 FR 50426, Sept. 21, 1998] ...

16 CFR 1211.24 - Product certification and labeling by manufacturers.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Product certification and labeling by manufacturers. 1211.24 Section 1211.24 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT... § 1211.24 Product certification and labeling by manufacturers. (a) Form of permanent label of...

76 FR 51402 - Manufacturer of Controlled Substances; Notice of Registration

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-18

..., 2011, 76 FR 25375, Siemens Healthcare Diagnostics Inc., Attn: RA, 100 GBC Drive, Mail Stop 514, Newark.... 823(a) and determined that the registration of Siemens Healthcare Diagnostics Inc., to manufacture the... has investigated Siemens Healthcare Diagnostics Inc., to ensure that the company's registration is...

75 FR 76756 - Manufacturer of Controlled Substances; Notice of Registration

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-09

..., 2010, (75 FR 47029), Johnson Matthey Pharma Services, 70 Flagship Drive, North Andover, Massachusetts... that the registration of Johnson Matthey Pharma Services to manufacture the listed basic classes of... Matthey Pharma Services to ensure that the company's registration is consistent with the public interest...

76 FR 51402 - Manufacturer of Controlled Substances; Notice of Registration

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-18

..., 2011, 76 FR 25376, Johnson Matthey Pharma Services, 70 Flagship Drive, North Andover, Massachusetts... that the registration of Johnson Matthey Pharma Services to manufacture the listed basic classes of... Matthey Pharma Services to ensure that the company's registration is consistent with the public interest...

75 FR 53722 - Manufacturer of Controlled Substances; Notice of Registration

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-01

..., 2010, (75 FR 14189), Rhodes Technologies, 498 Washington Street, Coventry, Rhode Island 02816, made... Technologies to manufacture the listed basic classes of controlled substances is consistent with the public interest at this time. DEA has investigated Rhodes Technologies to ensure that the company's registration...

76 FR 5829 - Manufacturer of Controlled Substances; Notice of Registration

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-02

... 1, 2010, 75 FR 53719, Cambridge Isotope Lab, 50 Frontage Road, Andover, Massachusetts 01810, made... determined that the registration of Cambridge Isotope Lab to manufacture the listed basic class of controlled substance is consistent with the public interest at this time. DEA has [[Page 5830

76 FR 56784 - Safe and Healthy Homes Investment Partnerships: Request for Comments

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-14

... DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT [Docket No. FR-5555-N-01] Safe and Healthy Homes... Regulations Division, Office of General Counsel, Department of Housing and Urban Development, 451 7th Street... Healthy Homes and Lead Hazard Control, Department of Housing and Urban Development, 451 7th Street, SW...

New Whole-House Solutions Case Study: Technology Solutions for New Manufactured Homes, Idaho, Oregon, and Washington

DOE Office of Scientific and Technical Information (OSTI.GOV)

BA-PIRC

2013-11-01

The Building America Partnership for Improved Residential Construction, the Bonneville Power Administration (BPA), and Northwest Energy Works (NEW), the current Northwest Energy Efficient Manufactured Housing Program (NEEM) administrator, have been collaborating to conduct research on new specifications that would improve on the energy requirements of a NEEM home. In its role as administrator, NEW administers the technical specs, performs research and engineering analysis, implements ongoing construction quality management procedures, and maintains a central database with home tracking. This project prototyped and assessed the performances of cost-effective high performance building assemblies and mechanical systems that are not commonly deployed in themore » manufacturing setting. The package of measures is able to reduce energy used for space conditioning, water heating and lighting by 50 percent over typical manufactured homes produced in the northwest.« less

24 CFR 3280.3 - Manufactured home procedural and enforcement regulations and consumer manual requirements.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 5 2010-04-01 2010-04-01 false Manufactured home procedural and enforcement regulations and consumer manual requirements. 3280.3 Section 3280.3 Housing and Urban Development... consumer manual requirements. A manufacturer must comply with the requirements of this part 3280, part 3282...

75 FR 35104 - Sunshine Act Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-21

... Announcement: 75 FR 34183, June 16, 2010. STATUS: Open Meeting. PLACE: 100 F Street, NE., Washington, DC. DATE...: Cancellation of Meeting. The Open Meeting scheduled for Friday, June 18, 2010 at 10 a.m. has been cancelled..., 2010. Florence E. Harmon, Deputy Secretary. [FR Doc. 2010-15011 Filed 6-17-10; 11:15 am] BILLING CODE P ...

75 FR 44287 - Manufacturer of Controlled Substances; Notice of Registration

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-28

..., 2010, (75 FR 14189), Siegfried (USA), 33 Industrial Park Road, Pennsville, New Jersey 08070, made... determined that the registration of Siegfried (USA) to manufacture the listed basic classes of controlled substances is consistent with the public interest at this time. DEA has investigated Siegfried (USA) to...

75 FR 69466 - Manufacturer of Controlled Substances; Notice of Registration

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-12

..., 2010, (75 FR 20001), Siemens Healthcare Diagnostics Inc., Attn: RA, 100 GBC Drive, Mail Stop 514... Siemens Healthcare Diagnostics Inc. to manufacture the listed basic classes of controlled substances is consistent with the public interest at this time. DEA has investigated Siemens Healthcare Diagnostics Inc. to...

Mechanism-based site-directed mutagenesis to shift the optimum pH of the phenylalanine ammonia-lyase from Rhodotorula glutinis JN-1.

PubMed

Zhu, Longbao; Zhou, Li; Cui, Wenjing; Liu, Zhongmei; Zhou, Zhemin

2014-09-01

Phenylalanine ammonia-lyase ( Rg PAL) from Rhodotorula glutinis JN-1 stereoselectively catalyzes the conversion of the l-phenylalanine into trans -cinnamic acid and ammonia, and was used in chiral resolution of dl-phenylalanine to produce the d-phenylalanine under acidic condition. However, the optimum pH of Rg PAL is 9 and the Rg PAL exhibits low catalytic efficiency at acidic side. Therefore, a mutant Rg PAL with a lower optimum pH is expected. Based on catalytic mechanism and structure analysis, we constructed a mutant Rg PAL-Q137E by site-directed mutagenesis, and found that this mutant had an extended optimum pH 7-9 with activity of 1.8-fold higher than that of the wild type at pH 7. As revealed by Friedel-Crafts-type mechanism of Rg PAL, the improvement of the Rg PAL-Q137E might be due to the negative charge of Glu137 which could stabilize the intermediate transition states through electrostatic interaction. The Rg PAL-Q137E mutant was used to resolve the racemic dl-phenylalanine, and the conversion rate and the ee D value of d-phenylalanine using Rg PAL-Q137E at pH 7 were increased by 29% and 48%, and achieved 93% and 86%, respectively. This work provides an effective strategy to shift the optimum pH which is favorable to further applications of Rg PAL.

24 CFR 3280.801 - Scope.

Code of Federal Regulations, 2010 CFR

2010-04-01

... of the National Electrical Code must be followed for electrical installations in manufactured homes... provisions of this standard apply to manufactured homes intended for connection to a wiring system nominally... circuit wiring in manufactured homes. [40 FR 58752, Dec. 18, 1975. Redesignated at 44 FR 20679, Apr. 6...

76 FR 21916 - Manufacturer of Controlled Substances; Notice of Registration

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-19

... December 29, 2010, 75 FR 82073, Siegfried (USA), Inc., 33 Industrial Park Road, Pennsville, New Jersey... registration of Siegfried (USA), Inc. to manufacture the listed basic classes of controlled substances is consistent with the public interest at this time. DEA has investigated Siegfried (USA), Inc. to ensure that...

76 FR 77257 - Manufacturer of Controlled Substances; Notice of Registration

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-12

... 18, 2011, 76 FR 51400, Cambridge Isotope Lab, 50 Frontage Road, Andover, Massachusetts 01810, made... determined that the registration of Cambridge Isotope Lab to manufacture the listed basic class of controlled substance is consistent with the public interest at this time. DEA has investigated Cambridge Isotope Lab to...

Roles of JnRAP2.6-like from the transition zone of black walnut in hormone signaling

Treesearch

Zhonglian Huang; Peng Zhao; Jose Medina; Richard Meilan; Keith Woeste

2013-01-01

An EST sequence, designated JnRAP2-like, was isolated from tissue at the heartwood/sapwood transition zone (TZ) in black walnut (Juglans nigra L). The deduced amino acid sequence of JnRAP2-like protein consists of a single AP2- containing domain with significant similarity to conserved AP2/ERF DNA-binding domains in other...

77 FR 75441 - Healthy Home and Lead Hazard Control Grant Programs Data Collection; Progress Reporting

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-20

... DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT [Docket No. FR-5603-N-93] Healthy Home and Lead Hazard... collection is designed to provide HUD timely information on progress of Healthy Homes Demonstration Program, Healthy Homes Technical Studies Program, Lead Base paint Hazard Control program, Lead Hazard Reduction...

Growth promotion and colonization of switchgrass (Panicum virgatum) cv. Alamo by bacterial endophyte Burkholderia phytofirmans strain PsJN

PubMed Central

2012-01-01

Background Switchgrass is one of the most promising bioenergy crop candidates for the US. It gives relatively high biomass yield and can grow on marginal lands. However, its yields vary from year to year and from location to location. Thus it is imperative to develop a low input and sustainable switchgrass feedstock production system. One of the most feasible ways to increase biomass yields is to harness benefits of microbial endophytes. Results We demonstrate that one of the most studied plant growth promoting bacterial endophytes, Burkholderia phytofirmans strain PsJN, is able to colonize and significantly promote growth of switchgrass cv. Alamo under in vitro, growth chamber, and greenhouse conditions. In several in vitro experiments, the average fresh weight of PsJN-inoculated plants was approximately 50% higher than non-inoculated plants. When one-month-old seedlings were grown in a growth chamber for 30 days, the PsJN-inoculated Alamo plants had significantly higher shoot and root biomass compared to controls. Biomass yield (dry weight) averaged from five experiments was 54.1% higher in the inoculated treatment compared to non-inoculated control. Similar results were obtained in greenhouse experiments with transplants grown in 4-gallon pots for two months. The inoculated plants exhibited more early tillers and persistent growth vigor with 48.6% higher biomass than controls. We also found that PsJN could significantly promote growth of switchgrass cv. Alamo under sub-optimal conditions. However, PsJN-mediated growth promotion in switchgrass is genotype specific. Conclusions Our results show B. phytofirmans strain PsJN significantly promotes growth of switchgrass cv. Alamo under different conditions, especially in the early growth stages leading to enhanced production of tillers. This phenomenon may benefit switchgrass establishment in the first year. Moreover, PsJN significantly stimulated growth of switchgrass cv. Alamo under sub-optimal conditions

Immunohistochemical expression of p16 in lipoblastomas.

PubMed

Cappellesso, Rocco; d'Amore, Emanuele S G; Dall'Igna, Patrizia; Guzzardo, Vincenza; Vassarotto, Elisa; Rugge, Massimo; Alaggio, Rita

2016-01-01

Lipoblastoma (LB) is a rare benign adipocytic tumor of childhood occasionally showing histological similarities to myxoid liposarcoma (ML) or well-differentiated liposarcoma (WDL). p16 immunohistochemistry has proved to be useful in distinguishing various types of liposarcomas, in particular WDL from lipoma, with higher sensitivity and specificity than MDM2 and CDK4 immunohistochemistry. In this study, we reported the histologic features of a series of 30 LB with emphasis on the potential diagnostic pitfalls and investigated the immunohistochemical expression of p16. Moreover, p16 immunostaining was performed in 16 liposarcomas (11 WDL and 5 ML), 16 lipomas, and 16 cases of liponecrosis in order to evaluate its usefulness in the differential diagnosis of challenging lesions occurring in older children. Overall, p16 immunostaining was positive in 3 LBs and in 12 out of 16 liposarcomas (10 WDL and 2 ML), with a sensitivity of 75%, a specificity of 90%, a positive predictive value of 80%, and a negative predictive value of 87%. All lipomas were p16 negative, whereas 5 liponecroses were positive. Accounting altogether the benign lesions versus liposarcomas, p16 showed a sensitivity of 75%, a specificity of 87%, a positive predictive value of 60%, and a negative predictive value of 93%. Our data suggest that a negative p16 immunostaining may be helpful in excluding a liposarcoma when occurring in unusual clinical contexts, such as in adolescence or late recurrence. However, such finding should be interpreted with caution since also some liposarcomas lack p16 and occasional LBs are positive. Copyright © 2015 Elsevier Inc. All rights reserved.

77 FR 73978 - Foreign-Trade Zone 148-Knoxville, TN, Toho Tenax America, Inc. (Carbon Fiber Manufacturing...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-12

...--Knoxville, TN, Toho Tenax America, Inc. (Carbon Fiber Manufacturing Authority), Opening of Comment Period on... manufacture carbon fiber for export and oxidized polyacrylonitrile fiber (Board Order 1868, 77 FR 69435, 11/19/2012). Board Order 1868 did not include authority to manufacture carbon fiber for the U.S. market; the...

Training a New Breed of Automated Manufacturing Technology Practitioners.

ERIC Educational Resources Information Center

Bainter, Jack J.

1986-01-01

A boom in industrial robotics has led numerous vocational institutions to launch extensive training programs in this specialty. ITT Educational Services offers two curriculum programs to train future manufacturing engineers. The firm's national director describes this model curriculum for meeting the needs of today's workforce. (JN)

10 CFR 51.105a - Public hearings in proceedings for issuance of manufacturing licenses.

Code of Federal Regulations, 2012 CFR

2012-01-01

... should be issued as proposed by the NRC's Director, Office of New Reactors or Director, Office of Nuclear Reactor Regulation, as appropriate. [73 FR 5724, Jan. 31, 2008] ... manufacturing licenses. 51.105a Section 51.105a Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) ENVIRONMENTAL...

10 CFR 51.105a - Public hearings in proceedings for issuance of manufacturing licenses.

Code of Federal Regulations, 2010 CFR

2010-01-01

... should be issued as proposed by the NRC's Director, Office of New Reactors or Director, Office of Nuclear Reactor Regulation, as appropriate. [73 FR 5724, Jan. 31, 2008] ... manufacturing licenses. 51.105a Section 51.105a Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) ENVIRONMENTAL...

10 CFR 51.105a - Public hearings in proceedings for issuance of manufacturing licenses.

Code of Federal Regulations, 2011 CFR

2011-01-01

... should be issued as proposed by the NRC's Director, Office of New Reactors or Director, Office of Nuclear Reactor Regulation, as appropriate. [73 FR 5724, Jan. 31, 2008] ... manufacturing licenses. 51.105a Section 51.105a Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) ENVIRONMENTAL...

10 CFR 51.105a - Public hearings in proceedings for issuance of manufacturing licenses.

Code of Federal Regulations, 2013 CFR

2013-01-01

... should be issued as proposed by the NRC's Director, Office of New Reactors or Director, Office of Nuclear Reactor Regulation, as appropriate. [73 FR 5724, Jan. 31, 2008] ... manufacturing licenses. 51.105a Section 51.105a Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) ENVIRONMENTAL...

10 CFR 51.105a - Public hearings in proceedings for issuance of manufacturing licenses.

Code of Federal Regulations, 2014 CFR

2014-01-01

... should be issued as proposed by the NRC's Director, Office of New Reactors or Director, Office of Nuclear Reactor Regulation, as appropriate. [73 FR 5724, Jan. 31, 2008] ... manufacturing licenses. 51.105a Section 51.105a Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) ENVIRONMENTAL...

Study of the nucleon radiative captures 8Li(n,γ)9Li, 9Be(p,γ)10B, 10Be(n,γ)11Be, 10B(p,γ)11C, and 16O(p,γ)17F at thermal and astrophysical energies

NASA Astrophysics Data System (ADS)

Dubovichenko, Sergey; Dzhazairov-Kakhramanov, Albert

We have studied the neutron-capture reactions 8Li(n,γ)9Li and its role in the primordial nucleosynthesis. The n +8Li →9Li + γ reaction has a significant astrophysical interest because it includes one of the variants of chain of primordial nucleosynthesis processes of the Universe and thermonuclear reactions in type II supernovae. Furthermore, we consider the 9Be(p,γ)10B reaction in the astrophysical energy range in the modified potential cluster model (MPCM) with splitting of orbital states according to Young tableaux and, in some cases, with forbidden states (FS). The reaction 9Be(p,γ)10B plays an important role in primordial and stellar nucleosynthesis of light elements in the p shell. Hydrogen burning in second-generation stars occurs via the proton-proton (pp) chain and CNO cycle, with the 9Be(p,γ)10B reaction serving as an intermediate link between these cycles. Furthermore, the possibility of describing available experimental data for the total reaction cross-sections of neutron radiative capture on 10Be at thermal and astrophysical energies has been shown. This reaction is a part of one of the variants of the chain of primordial nucleosynthesis of the Universe due to which the elements with a mass of A > 11-12 may be formed. The results in the field of study of thermonuclear proton-capture reaction on 10B at ultralow, i.e., astrophysical energies will be presented further. The possibility of description of the experimental data for the astrophysical S-factor of the proton radiative capture on 16O to the ground state (GS) of 17F was considered in the frame of the MPCM with FS and classification of the states according to Young tableaux. It was shown that on the basis of the E1 transitions from the states of p16O scattering to the GS of 17F in the p16O channel generally succeed to explain the value of measured cross-sections at astrophysical energies.

75 FR 41927 - Ideal Federal Savings Bank, Baltimore, Maryland; Notice of Appointment of Receiver

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-19

... DEPARTMENT OF THE TREASURY Office of Thrift Supervision Ideal Federal Savings Bank, Baltimore... contained in section 5(d)(2) of the Home Owners' Loan Act, the Office of Thrift Supervision has duly... Supervision. Sandra E. Evans, Federal Register Liaison. [FR Doc. 2010-17333 Filed 7-16-10; 8:45 am] BILLING...

Vaginal pH: Home-Use Tests

MedlinePlus

... streptococcus. How accurate is this test? Home vaginal pH tests showed good agreement with a doctor's diagnosis. However, ... to your doctor’s test? Yes. The home vaginal pH tests are practically identical to the ones sold to ...

77 FR 5849 - Manufacturer of Controlled Substances; Notice of Registration

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-06

... October 7, 2011, 76 FR 62449, Cambrex Charles City, Inc., 1205 11th Street, Charles City, Iowa 50616, made... Sufentanil (9740) II Fentanyl (9801) II The company will manufacture the listed controlled substances in bulk... factors in 21 U.S.C. 823(a) and determined that the registration of Cambrex Charles City, Inc. to...

New Whole-House Solutions Case Study: Northwest Energy Efficient Manufactured Housing Program High-Performance Test Homes - Pacific Northwest

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

2015-05-01

This project represents the third phase of a multi-year effort to develop and bring to market a High Performance Manufactured Home (HPMH). In this project, the Northwest Energy Efficient Manufactured Housing Program worked with Building America Partnership for Improved Residential Construction and Bonneville Power Administration to help four factory homebuilders build prototype zero energy ready manufactured homes, resulting in what is expected to be a 30% savings relative to the Building America Benchmark. (The actual % savings varies depending on choice of heating equipment and climate zone). Previous phases of this project created a HPMH specification and prototyped individual measuresmore » from the package to obtain engineering approvals and develop preliminary factory construction processes. This case study describes the project team's work during 2014 to build prototype homes to the HPMH specifications and to monitor the homes for energy performance and durability. Monitoring is expected to continue into 2016.« less

46 CFR 53.10-15 - Manufacturers' data report forms.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 2 2014-10-01 2014-10-01 false Manufacturers' data report forms. 53.10-15 Section 53.10-15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING HEATING BOILERS Tests, Inspection, Stamping, and Reporting (Article 5) § 53.10-15 Manufacturers' data report forms. The manufacturers' data report forms require...

46 CFR 53.10-15 - Manufacturers' data report forms.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 2 2010-10-01 2010-10-01 false Manufacturers' data report forms. 53.10-15 Section 53.10-15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING HEATING BOILERS Tests, Inspection, Stamping, and Reporting (Article 5) § 53.10-15 Manufacturers' data report forms. The manufacturers' data report forms require...

46 CFR 53.10-15 - Manufacturers' data report forms.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 2 2012-10-01 2012-10-01 false Manufacturers' data report forms. 53.10-15 Section 53.10-15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING HEATING BOILERS Tests, Inspection, Stamping, and Reporting (Article 5) § 53.10-15 Manufacturers' data report forms. The manufacturers' data report forms require...

46 CFR 53.10-15 - Manufacturers' data report forms.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 2 2013-10-01 2013-10-01 false Manufacturers' data report forms. 53.10-15 Section 53.10-15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING HEATING BOILERS Tests, Inspection, Stamping, and Reporting (Article 5) § 53.10-15 Manufacturers' data report forms. The manufacturers' data report forms require...

46 CFR 53.10-15 - Manufacturers' data report forms.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 2 2011-10-01 2011-10-01 false Manufacturers' data report forms. 53.10-15 Section 53.10-15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING HEATING BOILERS Tests, Inspection, Stamping, and Reporting (Article 5) § 53.10-15 Manufacturers' data report forms. The manufacturers' data report forms require...

24 CFR 3280.404 - Standard for egress windows and devices for use in manufactured homes.

Code of Federal Regulations, 2014 CFR

2014-04-01

....305(c)(1). (f) Protection of egress window openings in high wind areas. For homes designed to be... capable of resisting the design wind pressures specified in § 3280.305 without taking the home out of... Utilization in Manufactured Housing, except the exterior and interior pressure tests for components and...

24 CFR 982.622 - Manufactured home space rental: Rent to owner.

Code of Federal Regulations, 2012 CFR

2012-04-01

... collection provided by the owner. (b) Reasonable rent. (1) During the assisted tenancy, the rent to owner for... least annually during the assisted tenancy, the PHA must redetermine that the current rent to owner is a... rental of comparable spaces in the same manufactured home park or elsewhere. The owner must give the PHA...

24 CFR 982.622 - Manufactured home space rental: Rent to owner.

Code of Federal Regulations, 2013 CFR

2013-04-01

... collection provided by the owner. (b) Reasonable rent. (1) During the assisted tenancy, the rent to owner for... least annually during the assisted tenancy, the PHA must redetermine that the current rent to owner is a... rental of comparable spaces in the same manufactured home park or elsewhere. The owner must give the PHA...

10. PHOTOCOPY OF 'P. H. & F. M. ROOTS FOUNDARY ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

10. PHOTOCOPY OF 'P. H. & F. M. ROOTS FOUNDARY MANUFACTURERS OF ROOTS BLOWERS' FROM INDIANAPOLIS STAR, June 13, 1926, Gravure Section, p. 2 - P. H. & F. M. Roots Company, Eastern Avenue, Connersville, Fayette County, IN

16 CFR 300.16 - Ornamentation.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 16 Commercial Practices 1 2011-01-01 2011-01-01 false Ornamentation. 300.16 Section 300.16... REGULATIONS UNDER THE WOOL PRODUCTS LABELING ACT OF 1939 Labeling § 300.16 Ornamentation. (a) Where the wool... § 300.23 of this part (Rule 23). [29 FR 6625, May 21, 1964, as amended at 45 FR 44261, July 1, 1980] ...

78 FR 37995 - Energy Efficiency Standards for Manufactured Housing

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-25

... address the relationship between potential reductions in levels of natural air infiltration and both... typical baseline levels of air infiltration through recently-built manufactured homes and information on...

78 FR 10630 - Notice of Submission of Proposed Information Collection to OMB HOME Investment Partnerships...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-14

... Proposed Information Collection to OMB HOME Investment Partnerships Program: Correction AGENCY: Office of the Chief Information Officer, HUD. ACTION: Notice; Correction. SUMMARY: On February 8, 2013, at 77 FR..., Office of the Chief Information Officer. [FR Doc. 2013-03473 Filed 2-13-13; 8:45 am] BILLING CODE 4210-67...

77 FR 53209 - Notice of Proposed Information Collection: Comment Request; Home Equity Conversion Mortgage (HECM...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-31

... DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT [Docket No. FR-5607-N-28] Notice of Proposed Information Collection: Comment Request; Home Equity Conversion Mortgage (HECM) Insurance Application for the.... This Notice also lists the following information: Title of Proposal: Home Equity Conversion Mortgage...

75 FR 62410 - Notice of Proposed Information Collection: Comment Request; Home Equity Conversion Mortgage (HECM...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-08

... DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT [Docket No. FR-5380-N-39] Notice of Proposed Information Collection: Comment Request; Home Equity Conversion Mortgage (HECM) Insurance Application for the.... This Notice also lists the following information: Title of Proposal: Home equity Conversion Mortgage...

78 FR 36562 - 30-Day Notice of Proposed Information Collection: Home Equity Conversion Mortgage (HECM...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-18

... DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT [Docket No. FR-5683-N-44] 30-Day Notice of Proposed Information Collection: Home Equity Conversion Mortgage (HECM) Insurance Application for the Origination of... Information Collection: Home Equity Conversion Mortgage (HECM) Insurance Application for the Origination of...

Deposition of InP-ON-Si Substrates for Monolithic Integration of Advanced Electronics

DTIC Science & Technology

1991-04-19

efficiency, 3 low-cost solar cells , optoelectronic IC’s and GaAs IC’s on large-area Si substrates. Although much work has been done, the performance of the...1. Mesa Diode Fabrication A small piece was cut from the edge of the InP/InP solar cell ---;fr .12-1) I back contact was protected by photoresist. On...1~~~~ A,,).’,**** LLS - .* .’ ~*Ii* En - in - C *- -**0:; iU.)~ ILI Y a.E - CU CU tnJn ~c~C"+ m 00 -~4 CD J - -4i - - Ln cI- C2- El4 wi -r Lf

Development of an advanced uncooled 10-Gb DFB laser for volume manufacture

NASA Astrophysics Data System (ADS)

Burns, Gordon; Charles, Paul M.

2003-03-01

Optical communication systems operating at 10Gbit/s such as 10Gigabit Ethernet are becoming more and more important in Local Area Networks (LAN) and Metropolitan Area Networks (MAN). This market requires optical transceivers of low cost, size and power consumption. This drives a need for uncooled DFB lasers directly modulated at 10Gbit/s. This paper describes the development of a state of the art uncooled high speed DFB laser which is capable of being manufactured in high volume at the low cost demanded by the GbE market. A DFB laser was designed by developing technological building blocks within the 'conventional" InGaAsP materials system, using existing well proven manufacturing processes modules wherever possible, limiting the design risk to a few key areas where innovation was required. The temperature and speed performance of the InGaAsP SMQW active layer system was carefully optimized and then coupled with a low parasitic lateral confinement system. Using concurrent engineering, new processes were demonstrated to have acceptable process capability within a manufacturing fabrication environment, proving their ability to support high volume manufacturing requirements. The DFB laser fabricated was shown to operate at 100C chip temperature with an open eye at 10Gbit/s operation (with an extinction ratio >5dB). Up to 90C operation this DFB shows threshold current as low as 29mA, optical power as high as 13mW and it meets the 10Gb scaled Ethernet mask with extinction ratio >6dB. It was found that the high temperature dynamic behavior of these lasers could not be fully predicted from static test data. A production test strategy was therefore followed where equipment was designed to fully test devices/subassemblies at 100C and up to 20Gbit/s at key points in the product build. This facilitated the rapid optimisation of product yields upon manufacturing ramp up and minimization of product costs. This state of the art laser is now transferred into volume manufacture.

49 CFR 574.10 - Requirements for motor vehicle manufacturers.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 7 2011-10-01 2011-10-01 false Requirements for motor vehicle manufacturers. 574... RECORDKEEPING § 574.10 Requirements for motor vehicle manufacturers. Each motor vehicle manufacturer, or his designee, shall maintain a record of the new tires on or in each vehicle shipped by him or a motor vehicle...

78 FR 64021 - Manufacturer of Controlled Substances; Notice of Registration; Chemtos, LLC

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-25

... DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Registration; Chemtos, LLC By Notice dated June 18, 2013, and published in the Federal Register on July 1, 2013, 78 FR 39340, Chemtos, LLC., 14101 W. Highway 290, Building 2000B, Austin, Texas...

77 FR 75671 - Manufacturer of Controlled Substances; Notice of Registration; Chemtos, LLC

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-21

... DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Registration; Chemtos, LLC By Notice dated July 30, 2012, and published in the Federal Register on August 7, 2012, 77 FR 47116, Chemtos, LLC, 14101 W. Highway 290, Building 2000B, Austin, Texas...

78 FR 64019 - Manufacturer of Controlled Substances; Notice of Registration; Agilent Technologies

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-25

...; Notice of Registration; Agilent Technologies By Notice dated May 24, 2013, and published in the Federal Register on June 4, 2013, 78 FR 33441, Agilent Technologies, 25200 Commercentre Drive, Lake Forest... of Agilent Technologies to manufacture the listed basic classes of controlled substances is...

10 CFR 52.175 - Transfer of manufacturing license.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Transfer of manufacturing license. 52.175 Section 52.175 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS, AND APPROVALS FOR NUCLEAR POWER PLANTS Manufacturing Licenses § 52.175 Transfer of manufacturing license. A manufacturing license...

Youngstown MAP, Ohio. Revised Uniform Summary of Surface Weather Observations (RUSSWO). Parts A-F.

DTIC Science & Technology

1982-05-10

Air Weather Service ( MAC ) SCuOL2., IL 6222 R- UmmRm m "PJ M MOP Fr 4 JUN SURFACE WEATHER OSVAIWJ YOUNGSTOWN MAP OH MC #725250 N 41 16 W 080 40 ELD...percentage frequency of distribution tables OHIO YOUNGSTIOWN M "P, OHIO 20. and dew point temperatures and relative humidity); and (F) Pressure Summnary...p.ouIwuIis P i o m Qm 1 ---- .0 YN - :, 7 -AL CLIMATOLO’Y RA"CH 7 .I*.T 7C WEATHER CONDITIONS .ATH’p SEPVICE/mAC CNIIN -, JN,.S7 %N MAP OH 73-81 A U G

Standard Operating Procedure - Manufacture of Carbon Fibre Reinforced Plastic Waveguides and Slotted Waveguide Antennas, Version 1.0

DTIC Science & Technology

2011-06-01

aerospace grade carbon fibre reinforced plastic (CFRP) prepreg . RELEASE LIMITATION Approved for public release UNCLASSIFIED Report...arrays manufactured from aerospace grade carbon fibre reinforced plastic (CFRP) prepreg . 15. SUBJECT TERMS 16. SECURITY CLASSIFICATION OF: 17. LIMITATION...CFRP) prepreg tape and fabric. This report details Version 1.0 of a Standard Operating Procedure for this manufacture. UNCLASSIFIED

49 CFR 585.16 - Records.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 7 2011-10-01 2011-10-01 false Records. 585.16 Section 585.16 Transportation... Requirements § 585.16 Records. Each manufacturer shall maintain records of the Vehicle Identification Number of... manufacturer shall maintain records of the Vehicle Identification Number of each vehicle for which information...

49 CFR 585.16 - Records.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 7 2014-10-01 2014-10-01 false Records. 585.16 Section 585.16 Transportation... Requirements § 585.16 Records. Each manufacturer shall maintain records of the Vehicle Identification Number of... manufacturer shall maintain records of the Vehicle Identification Number of each vehicle for which information...

49 CFR 585.16 - Records.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 7 2012-10-01 2012-10-01 false Records. 585.16 Section 585.16 Transportation... Requirements § 585.16 Records. Each manufacturer shall maintain records of the Vehicle Identification Number of... manufacturer shall maintain records of the Vehicle Identification Number of each vehicle for which information...

49 CFR 585.16 - Records.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 7 2013-10-01 2013-10-01 false Records. 585.16 Section 585.16 Transportation... Requirements § 585.16 Records. Each manufacturer shall maintain records of the Vehicle Identification Number of... manufacturer shall maintain records of the Vehicle Identification Number of each vehicle for which information...

77 FR 43864 - Manufacturer of Controlled Substances; Notice of Registration; Rhodes Technologies

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-26

...; Notice of Registration; Rhodes Technologies By Notice dated April 17, 2012, and published in the Federal Register on April 26, 2012, 77 FR 24986, Rhodes Technologies, 498 Washington Street, Coventry, Rhode Island... Technologies to manufacture the listed basic classes of controlled substances is consistent with the public...

32 CFR 553.16 - Persons eligible for burial in Soldiers' Home National Cemetery.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 3 2010-07-01 2010-07-01 true Persons eligible for burial in Soldiers' Home National Cemetery. 553.16 Section 553.16 National Defense Department of Defense (Continued) DEPARTMENT OF... eligible for burial in Soldiers' Home National Cemetery. The Board of Commissioners of the US Soldiers' and...

Home parenteral nutrition in children: the Polish experience.

PubMed

Ksiazyk, J; Lyszkowska, M; Kierkus, J; Bogucki, K; Ratyńska, A; Tondys, B; Socha, J

1999-02-01

Home parenteral nutrition has become routine for management of intestinal failure in patients. In Poland the main obstacle to widespread use of home parenteral nutrition is the lack of interest of commercial companies in delivering feedings and ancillaries to patients. Twenty-five home parenteral nutrition patients aged from 4 months to more than 13 years were reviewed. The mother or both parents were trained in home parenteral nutrition techniques for 4 to 6 weeks and compounded the nutrients themselves at home. The mean duration of home parenteral nutrition was 10,117 patient days. Hospital stays of patients receiving parenteral feedings were significantly shorter than the duration of administration of home parenteral nutrition (p < 0.001). Eleven children are continuing the home parenteral nutrition program. Eighty-three catheters were used in these patients. The rate of catheter occlusion decreased within the observation period, and in 1997 not one case of occlusion was observed. In 1997 only three catheters were removed during 7.8 patient years, and the overall incidence of catheter-related complications was 0.38 per patient year. The overall occurrence of septicemia was one case in 516 days and of catheter infection was one in 459 days. In 1997 a catheter was infected on average of once every 1419 days. There was significant improvement in the z score for weight during therapy. The average monthly cost of nutrients and ancillary items was approximately $1200 (4200 Polish zlotys [PLN]). These costs are 1.6 to 3 times lower than those recorded in other studies. Home parenteral nutrition in children with nutrients mixed by caregivers in the home setting is a safe and appropriate method of treatment that can be used in countries where home parenteral nutrition solutions are not manufactured or where commercial home parenteral nutrition is not economically feasible.

Needed: Physical Educators on the Nursing Home Team.

ERIC Educational Resources Information Center

Hooks, Bettie; Hooks, Edgar W., Jr.

1981-01-01

Social interaction and physical activity are important aspects of health maintenance for the aged. A holistic approach to the care of the elderly in nursing homes would involve a team of professionals who encourage residents to pursue such tasks as adaptation to loss, and maintenance of physical activity to retain function. (JN)

16 CFR 1203.34 - Product certification and labeling by manufacturers (including importers).

Code of Federal Regulations, 2010 CFR

2010-01-01

... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Product certification and labeling by....34 Product certification and labeling by manufacturers (including importers). (a) Form of permanent... the requirements of this subpart has been performed by or for the foreign manufacturer of the product...

16 CFR 16.10 - Minutes and transcripts of meetings.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Minutes and transcripts of meetings. 16.10 Section 16.10 Commercial Practices FEDERAL TRADE COMMISSION ORGANIZATION, PROCEDURES AND RULES OF PRACTICE ADVISORY COMMITTEE MANAGEMENT § 16.10 Minutes and transcripts of meetings. (a) Detailed minutes of each...

Period Determination for (23621) 1996 PA, (29564) 1998 ED6 and (31775) 1999 JN122

NASA Astrophysics Data System (ADS)

Marchini, Alessandro; Papini, Riccardo; Salvaggio, Fabio

2018-01-01

Photometric observations of three asteroids were conducted from the Astronomical Observatory of the University of Siena (Italy) in order to determine their synodic rotation periods. For (23621) 1996 PA, a Marscrosser asteroid, we found a period of 2.666 ± 0.001 h with an amplitude of 0.10 mag. For the two main-belt asteroids (29564) 1998 ED6 and (31775) 1999 JN122, we found, respectively, a period of 8.434 ± 0.002 h with an amplitude of 0.57 mag and a period of 4.319 ± 0.01 h with an amplitude of 0.12 mag.

76 FR 5818 - Notice of Submission of Proposed Information Collection to OMB Home Equity Conversion Mortgage...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-02

... DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT [Docket No. FR-5480-N-09] Notice of Submission of Proposed Information Collection to OMB Home Equity Conversion Mortgage (HECM) Insurance Application for...: Title of Proposal: Home Equity Conversion Mortgage (HECM) Insurance Application for Reverse Mortgages...

77 FR 30027 - Manufacturer of Controlled Substances; Notice of Registration; Siegfried (USA)

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-21

...; Notice of Registration; Siegfried (USA) By Notice dated January 6, 2012, and published in the Federal Register on January 17, 2012, 77 FR 2323, Siegfried (USA), 33 Industrial Park Road, Pennsville, New Jersey... U.S.C. 823(a) and determined that the registration of Siegfried (USA), to manufacture the listed...

78 FR 5500 - Manufacturer of Controlled Substances; Notice of Registration; Chemic Laboratories, Inc.

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-25

...; Notice of Registration; Chemic Laboratories, Inc. By Notice dated September 25, 2012, and published in the Federal Register on October 2, 2012, 77 FR 60144, Chemic Laboratories, Inc., 480 Neponset Street... Chemic Laboratories, Inc., to manufacture the listed basic class of controlled substance is consistent...

24 CFR 3286.9 - Manufacturer shipment responsibilities.

Code of Federal Regulations, 2010 CFR

2010-04-01

... instructions. The manufacturer is required to provide with each manufactured home, installation designs and... HOUSING AND URBAN DEVELOPMENT MANUFACTURED HOME INSTALLATION PROGRAM Generally Applicable Provisions and... the time that each manufactured home is shipped by a manufacturer, the manufacturer must provide HUD...

75 FR 62413 - Notice of Proposed Information Collection: Comment Request; HUD-Owned Real Estate-Dollar Home...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-08

... DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT [Docket No. FR-5380-N-38] Notice of Proposed Information Collection: Comment Request; HUD- Owned Real Estate--Dollar Home Sales Program AGENCY: Office of... information: Title of Proposal: HUD-Owned Real Estate--Dollar Home Sales Program. OMB Control Number, if...

Use of Over-the-Counter and Home Remedies by College Students.

ERIC Educational Resources Information Center

Cafferata, Gail L.; And Others

1980-01-01

This study was undertaken to attempt to understand the prevalence, factors in selection, and safety of nonprescription drugs and home remedies by a population of college students. Results suggest the need for health education programs in stress/anxiety management, skin care, and gastrointestinal problems. (JN)

78 FR 12103 - Manufacturer of Controlled Substances; Notice of Registration; Cody Laboratories, Inc.

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-21

...; Notice of Registration; Cody Laboratories, Inc. By Notice dated November 1, 2012, and published in the Federal Register on November 9, 2012, 77 FR 67398, Cody Laboratories, Inc., ATTN: Richard Asherman, 601... of Cody Laboratories, Inc., to manufacture the listed basic classes of controlled substances is...

Manufacturing development of DC-10 advanced rudder

NASA Technical Reports Server (NTRS)

Cominsky, A.

1979-01-01

The design, manufacture, and ground test activities during development of production methods for an advanced composite rudder for the DC-10 transport aircraft are described. The advanced composite aft rudder is satisfactory for airline service and a cost saving in a full production manufacturing mode is anticipated.

16 CFR 503.3 - Name and place of business of manufacturer, packer, or distributor.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Name and place of business of manufacturer... LABELING ACT STATEMENTS OF GENERAL POLICY OR INTERPRETATION § 503.3 Name and place of business of manufacturer, packer, or distributor. To clarify the identity of a manufacturer, packer, or distributor for the...

42 CFR 406.2 - Scope.

Code of Federal Regulations, 2010 CFR

2010-10-01

..., home health services, and hospice care. [48 FR 56026, Dec. 16, 1983, as amended at 50 FR 33033, Aug. 16... 42 Public Health 2 2010-10-01 2010-10-01 false Scope. 406.2 Section 406.2 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES MEDICARE PROGRAM HOSPITAL...

Comparative genome analysis of Burkholderia phytofirmans PsJN reveals a wide spectrum of endophytic lifestyles based on interaction strategies with host plants

PubMed Central

Mitter, Birgit; Petric, Alexandra; Shin, Maria W.; Chain, Patrick S. G.; Hauberg-Lotte, Lena; Reinhold-Hurek, Barbara; Nowak, Jerzy; Sessitsch, Angela

2013-01-01

Burkholderia phytofirmans PsJN is a naturally occurring plant-associated bacterial endophyte that effectively colonizes a wide range of plants and stimulates their growth and vitality. Here we analyze whole genomes, of PsJN and of eight other endophytic bacteria. This study illustrates that a wide spectrum of endophytic life styles exists. Although we postulate the existence of typical endophytic traits, no unique gene cluster could be exclusively linked to the endophytic lifestyle. Furthermore, our study revealed a high genetic diversity among bacterial endophytes as reflected in their genotypic and phenotypic features. B. phytofirmans PsJN is in many aspects outstanding among the selected endophytes. It has the biggest genome consisting of two chromosomes and one plasmid, well-equipped with genes for the degradation of complex organic compounds and detoxification, e.g., 24 glutathione-S-transferase (GST) genes. Furthermore, strain PsJN has a high number of cell surface signaling and secretion systems and harbors the 3-OH-PAME quorum-sensing system that coordinates the switch of free-living to the symbiotic lifestyle in the plant-pathogen R. solanacearum. The ability of B. phytofirmans PsJN to successfully colonize such a wide variety of plant species might be based on its large genome harboring a broad range of physiological functions. PMID:23641251

78 FR 52802 - Manufacturer of Controlled Substances; Notice of Registration; Morton Grove Pharmaceuticals

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-26

...; Notice of Registration; Morton Grove Pharmaceuticals By Notice dated March 12, 2013, and published in the Federal Register on March 20, 2013, 78 FR 17231, Morton Grove Pharmaceuticals, 6451 Main Street, Morton... 21 U.S.C. 823(a), and determined that the registration of Morton Grove Pharmaceuticals to manufacture...

77 FR 38085 - Manufacturer of Controlled Substances; Notice of Registration; Cayman Chemical Company

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-26

...; Notice of Registration; Cayman Chemical Company By Notice dated March 8, 2012, and published in the Federal Register on March 20, 2012, 77 FR 16263, Cayman Chemical Company, 1180 East Ellsworth Road, Ann... registration of Cayman Chemical Company to manufacture the listed basic classes of controlled substances is...

77 FR 75672 - Manufacturer of Controlled Substances, Notice of Registration, Halo Pharmaceutical, Inc.

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-21

..., Notice of Registration, Halo Pharmaceutical, Inc. By Notice dated July 30, 2012, and published in the Federal Register on August 7, 2012, 77 FR 47114, Halo Pharmaceutical, Inc., 30 North Jefferson Road... 21 U.S.C. 823(a), and determined that the registration of Halo Pharmaceutical, Inc., to manufacture...

77 FR 64143 - Manufacturer of Controlled Substances; Notice of Registration; Cambridge Isotope Lab

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-18

...; Notice of Registration; Cambridge Isotope Lab By Notice dated June 18, 2012, and published in the Federal Register on June 26, 2012, 77 FR 38086, Cambridge Isotope Lab, 50 Frontage Road, Andover, Massachusetts....C. 823(a) and determined that the registration of Cambridge Isotope Lab to manufacture the listed...

16 CFR 1102.30 - Publication of manufacturer comments.

Code of Federal Regulations, 2011 CFR

2011-01-01

... ACT REGULATIONS PUBLICLY AVAILABLE CONSUMER PRODUCT SAFETY INFORMATION DATABASE (Eff. Jan. 10, 2011....24, and 1102.26, the Commission will publish in the Database manufacturer comments submitted in...

Utilization of recombinant Trichoderma reesei expressing Aspergillus aculeatus β-glucosidase I (JN11) for a more economical production of ethanol from lignocellulosic biomass.

PubMed

Treebupachatsakul, Treesukon; Shioya, Koki; Nakazawa, Hikaru; Kawaguchi, Takashi; Morikawa, Yasushi; Shida, Yosuke; Ogasawara, Wataru; Okada, Hirofumi

2015-12-01

The capacity of Trichoderma reesei cellulase to degrade lignocellulosic biomass has been enhanced by the construction of a recombinant T. reesei strain expressing Aspergillus aculeatus β-glucosidase I. We have confirmed highly efficient ethanol production from converge-milled Japanese cedar by recombinant T. reesei expressing A. aculeatus β-glucosidase I (JN11). We investigated the ethanol productivity of JN11 and compared it with the cocktail enzyme T. reesei PC-3-7 with reinforced cellobiase activity by the commercial Novozyme 188. Results showed that the ethanol production efficiency under enzymatic hydrolysis of JN11 was comparable to the cocktail enzyme both on simultaneous saccharification and fermentation (SSF) or separate hydrolysis and fermentation (SHF) processes. Moreover, the cocktail enzyme required more protein loading for attaining similar levels of ethanol conversion as JN11. We propose that JN11 is an intrinsically economical enzyme that can eliminate the supplementation of BGL for PC-3-7, thereby reducing the cost of industrial ethanol production from lignocellulosic biomass. Copyright © 2015 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.

77 FR 66179 - Manufacturing Council

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-02

... received by the Office of Advisory Committees of the Department of Commerce by close of business on... must be received by the Office of Advisory Committees by close of business on Friday, November 16, 2012... responsibility) that are leaders within their local manufacturing communities and industry sectors. The Council's...

38 CFR 36.4252 - Loans for purchase or refinancing of a manufactured home.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2012-07-01 2012-07-01 false Loans for purchase or refinancing of a manufactured home. 36.4252 Section 36.4252 Pensions, Bonuses, and Veterans' Relief DEPARTMENT... include funds (or be augmented by a separate loan) to finance all or part of the cost of acquisition by...

38 CFR 36.4252 - Loans for purchase or refinancing of a manufactured home.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2011-07-01 2011-07-01 false Loans for purchase or refinancing of a manufactured home. 36.4252 Section 36.4252 Pensions, Bonuses, and Veterans' Relief DEPARTMENT... include funds (or be augmented by a separate loan) to finance all or part of the cost of acquisition by...

38 CFR 36.4252 - Loans for purchase or refinancing of a manufactured home.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2014-07-01 2014-07-01 false Loans for purchase or refinancing of a manufactured home. 36.4252 Section 36.4252 Pensions, Bonuses, and Veterans' Relief DEPARTMENT... include funds (or be augmented by a separate loan) to finance all or part of the cost of acquisition by...

38 CFR 36.4252 - Loans for purchase or refinancing of a manufactured home.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2013-07-01 2013-07-01 false Loans for purchase or refinancing of a manufactured home. 36.4252 Section 36.4252 Pensions, Bonuses, and Veterans' Relief DEPARTMENT... include funds (or be augmented by a separate loan) to finance all or part of the cost of acquisition by...

38 CFR 36.4252 - Loans for purchase or refinancing of a manufactured home.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Loans for purchase or refinancing of a manufactured home. 36.4252 Section 36.4252 Pensions, Bonuses, and Veterans' Relief DEPARTMENT... include funds (or be augmented by a separate loan) to finance all or part of the cost of acquisition by...

78 FR 30333 - Manufacturer of Controlled Substances; Notice of Registration; Siegfried (Usa), Llc.

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-22

...; Notice of Registration; Siegfried (Usa), Llc. By Notice dated November 19, 2012, and published in the Federal Register on November 27, 2012, 77 FR 70825, Siegfried (USA), LLC., 33 Industrial Park Road... 21 U.S.C. 823(a) and determined that the registration of Siegfried (USA), LLC., to manufacture the...

78 FR 64020 - Manufacturer of Controlled Substances; Notice of Registration; Siegfried USA, LLC

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-25

...; Notice of Registration; Siegfried USA, LLC By Notice dated May 22, 2013, and published in the Federal Register on May 30, 2013, 78 FR 32458, Siegfried USA, LLC., 33 Industrial Park Road, Pennsville, New Jersey... determined that the registration of Siegfried USA, LLC., to manufacture the listed basic class of controlled...

75 FR 29995 - Sunshine Act Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-28

... COMMODITY FUTURES TRADING COMMISSION Sunshine Act Meetings TIME AND DATE: 2 p.m., Wednesday, June 16, 2010. PLACE: 1155 21st St., NW., Washington, DC, 9th Floor Commission Conference Room. [[Page.... [FR Doc. 2010-13084 Filed 5-26-10; 4:15 pm] BILLING CODE 6351-01-P ...

Science for the Home: New Products Tackle Such Weighty Subjects as Immunology, Chemistry.

ERIC Educational Resources Information Center

Mace, Scott

1984-01-01

Discusses trends in science software for home and educational use. Examples of software on various science topics are provided, including packages which revolve around such television shows as "Nova" and "Voyage of the Mimi" and those produced by the Human Engineering Software. (JN)

75 FR 62333 - Airworthiness Directives; Hamilton Sundstrand Propellers Model 247F Propellers

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-08

...., Monday through Friday, except Federal holidays. The AD docket contains this proposed AD, the regulatory... that the 247F propeller blades, P/N 817370-1, S/Ns FR2449 to FR2958 inclusive, FR20010710 to FR20010722 inclusive, and FR20010723RT to FR20020127RT inclusive, manufactured since January 1999, might also have...

16 CFR Appendix J1 to Part 305 - Pool Heaters-Gas

Code of Federal Regulations, 2011 CFR

2011-01-01

... 16 Commercial Practices 1 2011-01-01 2011-01-01 false Pool Heaters-Gas J1 Appendix J1 to Part 305... Part 305—Pool Heaters—Gas Range Information Manufacturer's rated heating capacity Range of Thermal Efficiencies (percent) Natural Gas Low High Propane Low High All capacities 79.0 95.0 79.0 95.0 [72 FR 49983...

16 CFR Appendix J1 to Part 305 - Pool Heaters-Gas

Code of Federal Regulations, 2010 CFR

2010-01-01

... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Pool Heaters-Gas J1 Appendix J1 to Part 305... Part 305—Pool Heaters—Gas Range Information Manufacturer's rated heating capacity Range of Thermal Efficiencies (percent) Natural Gas Low High Propane Low High All capacities 79.0 95.0 79.0 95.0 [72 FR 49983...

16 CFR 1205.35 - Product certification and labeling by manufacturers.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Product certification and labeling by manufacturers. 1205.35 Section 1205.35 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS SAFETY STANDARD FOR WALK-BEHIND POWER LAWN MOWERS Certification § 1205.35 Product...

77 FR 31390 - Manufacturer of Controlled Substances; Notice of Registration; Siemens Healthcare Diagnostics, Inc.

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-25

...; Notice of Registration; Siemens Healthcare Diagnostics, Inc. By Notice dated January 26, 2012, and published in the Federal Register on February 6, 2012, 77 FR 5847, Siemens Healthcare Diagnostics Inc., 100... Healthcare Diagnostics Inc., to manufacture the listed basic classes of controlled substances is consistent...

78 FR 19017 - Manufacturer of Controlled Substances; Notice of Registration; Siemens Healthcare Diagnostics, Inc.

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-28

...; Notice of Registration; Siemens Healthcare Diagnostics, Inc. By Notice dated November 27, 2012, and published in the Federal Register on December 5, 2012, 77 FR 72409, Siemens Healthcare Diagnostics Inc... Siemens Healthcare Diagnostics Inc., to manufacture the listed basic classes of controlled substances is...

Breastfeeding status and marketing practices of baby food manufactured in nursing homes.

PubMed

Mathur, G P; Pandey, P K; Mathur, S; Mishra, V K; Singh, K; Bhatt, O P; Loomba, R K; Luthra, C; Taneja, S; Kapoor, R

1993-11-01

In January 1993 in Kanpur, India, a survey of 7 private nursing homes revealed that infant formula was given to most newborns (52.4%). The most common brands included Lactogen-I, Milk Care, Raptakos, Dexolac Special Care, and Lactodex. Staff at 5 nursing homes gave prelacteal feeds (water, glucose water, and infant formula) to newborns when they were separated from their mothers. Staff at only 2 nursing homes gave the newborn to the mother immediately after delivery. The longest period between delivery and giving the newborn to the mother was 24 hours. All but one of the nursing homes did not know about the government policy and the recent bill that bars free or low-cost infant formula supplies to hospitals. The administration of the nursing homes did not inform the procurement department, in writing, of the government policy. 4 nursing homes bought low-cost supplies of infant formula from the companies. The companies sold the infant formula to the nursing homes at a price 48.3% to 86.7% lower than the market price. Medical stores inside or outside the nursing homes sold the infant formula to parents at the other 3 homes. The nursing homes used, on average, 2-50 kg/month. Nestle (Lactogen-I) and Dalmia Industries (Milk Care) had a monopoly in infant formula in 4 and 3 nursing homes, respectively. Infant formula was in stock in 5 nursing homes. None of the nursing homes gave mothers free or low-cost infant formula at discharge. Lower than market price and increased number of calls to the hospitals and physicians by company personnel were marketing techniques used by the manufacturers to maintain market share. These results show that, despite government policy and the bill, hospitals continue to use infant formula. The government should use the mass media to increase awareness about its policy on infant foods and the concept of the Baby Friendly Hospital.

75 FR 51016 - Sunshine Act Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-18

... COMMODITY FUTURES TRADING COMMISSION Sunshine Act Meetings Time and Date: 11 a.m., Friday September 10, 2010. Place: 1155 21st St., NW., Washington, DC, 9th Floor Commission Conference Room. Status.... [FR Doc. 2010-20598 Filed 8-16-10; 4:15 pm] BILLING CODE 6351-01-P ...

77 FR 70188 - Manufacturer of Controlled Substances; Notice of Registration; Boehringer Ingelheim Chemicals, Inc.

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-23

...; Notice of Registration; Boehringer Ingelheim Chemicals, Inc. By Notice dated July 17, 2012, and published in the Federal Register on July 26, 2012, 77 FR 43863, Boehringer Ingelheim Chemicals, Inc., 2820 N... Ingelheim Chemicals, Inc., to manufacture the listed basic classes of controlled substances is consistent...

78 FR 12104 - Manufacturer of Controlled Substances; Notice of Registration; INB Hauser Pharmaceutical Services...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-21

...; Notice of Registration; INB Hauser Pharmaceutical Services, Inc. By Notice dated November 1, 2012, and published in the Federal Register on November 9, 2012, 77 FR 67398, InB Hauser Pharmaceutical Services, Inc... Hauser Pharmaceutical Services, Inc., to manufacture the listed basic class of controlled substance is...

77 FR 25133 - Foreign-Trade Zone 126, Temporary/Interim Manufacturing Authority, Brightpoint North America L.P...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-27

... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [Docket T-3-2012] Foreign-Trade Zone 126, Temporary/Interim Manufacturing Authority, Brightpoint North America L.P. (Cell Phone Kitting and... America L.P., to produce cell phone kits under FTZ procedures within FTZ 126--Site 23, in Reno, Nevada...

40 CFR 16.10 - Penalties.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Penalties. 16.10 Section 16.10 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL IMPLEMENTATION OF PRIVACY ACT OF 1974 § 16... or obtains any record concerning an individual from an agency under false pretenses shall be guilty...

10 CFR 611.207 - Small automobile and component manufacturers.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Small automobile and component manufacturers. 611.207... VEHICLES MANUFACTURER ASSISTANCE PROGRAM Facility/Funding Awards § 611.207 Small automobile and component... individuals; and (2) Manufactures automobiles or components of automobiles. (b) Set Aside—Of the amount of...

10 CFR 611.207 - Small automobile and component manufacturers.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Small automobile and component manufacturers. 611.207... VEHICLES MANUFACTURER ASSISTANCE PROGRAM Facility/Funding Awards § 611.207 Small automobile and component... individuals; and (2) Manufactures automobiles or components of automobiles. (b) Set Aside—Of the amount of...

10 CFR 611.207 - Small automobile and component manufacturers.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 4 2012-01-01 2012-01-01 false Small automobile and component manufacturers. 611.207... VEHICLES MANUFACTURER ASSISTANCE PROGRAM Facility/Funding Awards § 611.207 Small automobile and component... individuals; and (2) Manufactures automobiles or components of automobiles. (b) Set Aside—Of the amount of...

10 CFR 611.207 - Small automobile and component manufacturers.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 4 2014-01-01 2014-01-01 false Small automobile and component manufacturers. 611.207... VEHICLES MANUFACTURER ASSISTANCE PROGRAM Facility/Funding Awards § 611.207 Small automobile and component... individuals; and (2) Manufactures automobiles or components of automobiles. (b) Set Aside—Of the amount of...

10 CFR 611.207 - Small automobile and component manufacturers.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 4 2013-01-01 2013-01-01 false Small automobile and component manufacturers. 611.207... VEHICLES MANUFACTURER ASSISTANCE PROGRAM Facility/Funding Awards § 611.207 Small automobile and component... individuals; and (2) Manufactures automobiles or components of automobiles. (b) Set Aside—Of the amount of...

10 CFR 51.54 - Environmental report-manufacturing license.

Code of Federal Regulations, 2012 CFR

2012-01-01

... evaluation of alternative energy sources. (b) Each applicant for an amendment to a manufacturing license... 10 Energy 2 2012-01-01 2012-01-01 false Environmental report-manufacturing license. 51.54 Section 51.54 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) ENVIRONMENTAL PROTECTION REGULATIONS FOR...

10 CFR 51.54 - Environmental report-manufacturing license.

Code of Federal Regulations, 2011 CFR

2011-01-01

... evaluation of alternative energy sources. (b) Each applicant for an amendment to a manufacturing license... 10 Energy 2 2011-01-01 2011-01-01 false Environmental report-manufacturing license. 51.54 Section 51.54 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) ENVIRONMENTAL PROTECTION REGULATIONS FOR...

10 CFR 51.54 - Environmental report-manufacturing license.

Code of Federal Regulations, 2014 CFR

2014-01-01

... evaluation of alternative energy sources. (b) Each applicant for an amendment to a manufacturing license... 10 Energy 2 2014-01-01 2014-01-01 false Environmental report-manufacturing license. 51.54 Section 51.54 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) ENVIRONMENTAL PROTECTION REGULATIONS FOR...

10 CFR 51.54 - Environmental report-manufacturing license.

Code of Federal Regulations, 2010 CFR

2010-01-01

... evaluation of alternative energy sources. (b) Each applicant for an amendment to a manufacturing license... 10 Energy 2 2010-01-01 2010-01-01 false Environmental report-manufacturing license. 51.54 Section 51.54 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) ENVIRONMENTAL PROTECTION REGULATIONS FOR...

10 CFR 51.54 - Environmental report-manufacturing license.

Code of Federal Regulations, 2013 CFR

2013-01-01

... evaluation of alternative energy sources. (b) Each applicant for an amendment to a manufacturing license... 10 Energy 2 2013-01-01 2013-01-01 false Environmental report-manufacturing license. 51.54 Section 51.54 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) ENVIRONMENTAL PROTECTION REGULATIONS FOR...

78 FR 69134 - Manufacturer of Controlled Substances; Notice of Registration: AMPAC Fine Chemicals, LLC.

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-18

...; Notice of Registration: AMPAC Fine Chemicals, LLC. By Notice dated July 23, 2013, and published in the Federal Register on July 31, 2013, 78 FR 46372, AMPAC Fine Chemicals, LLC., Highway 50 and Hazel Avenue... AMPAC Fine Chemicals, LLC., to manufacture the listed basic classes of controlled substances is...

77 FR 24988 - Manufacturer of Controlled Substances; Notice of Registration; ISP Freetown Fine Chemicals

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-26

...; Notice of Registration; ISP Freetown Fine Chemicals By Notice dated October 8, 2010, and published in the Federal Register on October 20, 2010, 75 FR 64746, ISP Freetown Fine Chemicals, 238 South Main Street... Fine Chemicals, to manufacture the listed basic classes of controlled substances is consistent with the...

16 CFR 1102.12 - Manufacturer comments.

Code of Federal Regulations, 2012 CFR

2012-01-01

... PUBLICLY AVAILABLE CONSUMER PRODUCT SAFETY INFORMATION DATABASE Content Requirements § 1102.12 Manufacturer... Database if such manufacturer comment meets the following requirements: (1) Manufacturer comment relates to... publication in the Database. (2) Unique identifier. A manufacturer comment must state the unique identifier...

16 CFR 1102.12 - Manufacturer comments.

Code of Federal Regulations, 2014 CFR

2014-01-01

... PUBLICLY AVAILABLE CONSUMER PRODUCT SAFETY INFORMATION DATABASE Content Requirements § 1102.12 Manufacturer... Database if such manufacturer comment meets the following requirements: (1) Manufacturer comment relates to... publication in the Database. (2) Unique identifier. A manufacturer comment must state the unique identifier...

43 CFR 10.16 - Review committee.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Review committee. 10.16 Section 10.16... REPATRIATION REGULATIONS General § 10.16 Review committee. (a) General. The Review Committee will advise... recommendation, finding, report, or other action of the Review Committee is advisory only and not binding on any...

Childhood leukemia and parents' occupational and home exposures.

PubMed

Lowengart, R A; Peters, J M; Cicioni, C; Buckley, J; Bernstein, L; Preston-Martin, S; Rappaport, E

1987-07-01

A case-control study of children of ages 10 years and under in Los Angeles County was conducted to investigate the causes of leukemia. The mothers and fathers of acute leukemia cases and their individually matched controls were interviewed regarding specific occupational and home exposures as well as other potential risk factors associated with leukemia. Analysis of the information from the 123 matched pairs showed an increased risk of leukemia for children whose fathers had occupational exposure after the birth of the child to chlorinated solvents [odds ratio (OR) = 3.5, P = .01], spray paint (OR = 2.0, P = .02), dyes or pigments (OR = 4.5, P = .03), methyl ethyl ketone (CAS: 78-93-3; OR = 3.0, P = .05), and cutting oil (OR = 1.7, P = .05) or whose fathers were exposed during the mother's pregnancy with the child to spray paint (OR = 2.2, P = .03). For all of these, the risk associated with frequent use was greater than for infrequent use. There was an increased risk of leukemia for the child if the father worked in industries manufacturing transportation equipment (mostly aircraft) (OR = 2.5, P = .03) or machinery (OR = 3.0, P = .02). An increased risk was found for children whose parents used pesticides in the home (OR = 3.8, P = .004) or garden (OR = 6.5, P = .007) or who burned incense in the home (OR = 2.7, P = .007). The risk was greater for frequent use. Risk of leukemia was related to mothers' employment in personal service industries (OR = 2.7, P = .04) but not to specified occupational exposures. Risk related to fathers' exposure to chlorinated solvents, employment in the transportation equipment-manufacturing industry, and parents' exposure to household or garden pesticides and incense remains statistically significant after adjusting for the other significant findings.

Tobacco Smoking and Increased Risk of Death and Progression for Patients With p16-Positive and p16-Negative Oropharyngeal Cancer

PubMed Central

Gillison, Maura L.; Zhang, Qiang; Jordan, Richard; Xiao, Weihong; Westra, William H.; Trotti, Andy; Spencer, Sharon; Harris, Jonathan; Chung, Christine H.; Ang, K. Kian

2012-01-01

Purpose Tobacco smoking is associated with oropharynx cancer survival, but to what extent cancer progression or death increases with increasing tobacco exposure is unknown. Patients and Methods Patients with oropharynx cancer enrolled onto a phase III trial of radiotherapy from 1991 to 1997 (Radiation Therapy Oncology Group [RTOG] 9003) or of chemoradiotherapy from 2002 to 2005 (RTOG 0129) were evaluated for tumor human papillomavirus status by a surrogate, p16 immunohistochemistry, and for tobacco exposure by a standardized questionnaire. Associations between tobacco exposure and overall survival (OS) and progression-free survival (PFS) were estimated by Cox proportional hazards models. Results Prevalence of p16-positive cancer was 39.5% among patients in RTOG 9003 and 68.0% in RTOG 0129. Median pack-years of tobacco smoking were lower among p16-positive than p16-negative patients in both trials (RTOG 9003: 29 v 45.9 pack-years; P = .02; RTOG 0129: 10 v 40 pack-years; P < .001). After adjustment for p16 and other factors, risk of progression (PFS) or death (OS) increased by 1% per pack-year (for both, hazard ratio [HR], 1.01; 95% CI, 1.00 to 1.01; P = .002) or 2% per year of smoking (for both, HR, 1.02; 95% CI, 1.01 to 1.03; P < .001) in both trials. In RTOG 9003, risk of death doubled (HR, 2.19; 95% CI, 1.46 to 3.28) among those who smoked during radiotherapy after accounting for pack-years and other factors, and risk of second primary tumors increased by 1.5% per pack-year (HR, 1.015; 95% CI, 1.005 to 1.026). Conclusion Risk of oropharyngeal cancer progression and death increases directly as a function of tobacco exposure at diagnosis and during therapy and is independent of tumor p16 status and treatment. PMID:22565003

77 FR 55505 - Manufacturer of Controlled Substances; Notice of Registration; AMPAC Fine Chemicals LLC

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-10

...; Notice of Registration; AMPAC Fine Chemicals LLC By Notice dated May 11, 2012, and published in the Federal Register on May 21, 2012, 77 FR 30026, AMPAC Fine Chemicals LLC., Highway 50 and Hazel Avenue.... 823(a) and determined that the registration of AMPAC Fine Chemicals LLC., to manufacture the listed...

32 CFR 553.16 - Persons eligible for burial in Soldiers' Home National Cemetery.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 3 2014-07-01 2014-07-01 false Persons eligible for burial in Soldiers' Home National Cemetery. 553.16 Section 553.16 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY MILITARY RESERVATIONS AND NATIONAL CEMETERIES ARMY NATIONAL CEMETERIES § 553.16 Persons...

Two major pathways of penile carcinogenesis: HPV-induced penile cancers overexpress p16ink4a, HPV-negative cancers associated with dermatoses express p53, but lack p16ink4a overexpression.

PubMed

Mannweiler, Sebastian; Sygulla, Stephan; Winter, Elke; Regauer, Sigrid

2013-07-01

Penile squamous cell carcinomas (SCC) arise either through transforming infections with human papillomavirus (HPV) or independent of HPV, often in the background of lichen sclerosus (LS) and lichen planus (LP). Despite impact on therapy and prognosis, etiologic stratifications are missing in most histological diagnoses and publications about penile cancers/precursors. Classification of penile lesions into HPV-induced or HPV-negative via immunohistochemical demonstration of p16(ink4a) overexpression, a surrogate marker for transforming HPV-high-risk infections, and p53 expression in the absence of p16(ink4a) overexpression. Archival formalin-fixed material of 123 invasive penile cancers and 43 pre-invasive lesions was evaluated for the presence of LS, LP, 28 HPV genotypes, and expression of p53 and p16(ink4a). Seventy-two of 123 SCCs and 33 of 43 pre-invasive lesions showed p16(ink4a) overexpression independent of HPV-HR genotypes involved; 66 of 72 SCCs and 29 of 43 precursor lesions revealed a single HPV-high-risk-genotype (HPV-HR16 in 76% followed by HPV33, HPV31, HPV45, HPV18, HPV56); 5 of 72 SCCs and 4 of 43 precursor lesions revealed multiple HPV-HR-genotypes. One SCC revealed HPV-LR and HR-DNA. Fifty-one of 123 SCCs and 10 precursor lesions were p16(ink4a) negative, but showed nuclear p53 expression in tumor cells and basal keratinocytes. Forty-nine of 51 SCCs and 10 of 10 precursor lesions lacked HPV DNA. Two of 51 SCCs contained HPV18 and HPV45 DNA, respectively, but p16(ink4a) negativity classified them as non-HPV-induced. Twenty-seven of 51 SCCs showed peritumoral LS, 13 of 51 SCCs showed peritumoral LP, and 11 SCCs revealed no peritumoral tissue. Histologically, HPV-negative precursors showed hyperkeratotic, verrucous, atrophic, and basaloid differentiation. This was a retrospective study. p16(ink4a) overexpression identifies HPV-HR-induced penile carcinogenesis independent of HPV-HR genotype. p53 expression along with p16(ink4a) negativity identifies

40 CFR 52.2120 - Identification of plan.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Kraft Pulp and Paper Manufacturing 4/29/88 10/03/89 54 FR 40662. Section IV Portland Cement... Gins 3/24/86 2/17/87 52 FR 4772. Section VI Hot Mix Asphalt Plants 6/05/85 10/03/89 54 FR 40660.... Part C Surface Coating of Paper, Vinyl,& Fabric 8/22/79 12/16/81 46 FR 61268. Part D Surface Coating of...

Common variants on 2p16.1, 6p22.1 and 10q24.32 are associated with schizophrenia in Han Chinese population.

PubMed

Yu, H; Yan, H; Li, J; Li, Z; Zhang, X; Ma, Y; Mei, L; Liu, C; Cai, L; Wang, Q; Zhang, F; Iwata, N; Ikeda, M; Wang, L; Lu, T; Li, M; Xu, H; Wu, X; Liu, B; Yang, J; Li, K; Lv, L; Ma, X; Wang, C; Li, L; Yang, F; Jiang, T; Shi, Y; Li, T; Zhang, D; Yue, W

2017-07-01

Many schizophrenia susceptibility loci have been identified through genome-wide association studies (GWASs) in European populations. However, until recently, schizophrenia GWASs in non-European populations were limited to small sample sizes and have yielded few loci associated with schizophrenia. To identify genetic risk variations for schizophrenia in the Han Chinese population, we performed a two-stage GWAS of schizophrenia comprising 4384 cases and 5770 controls, followed by independent replications of 13 single-nucleotide polymorphisms in an additional 4339 schizophrenia cases and 7043 controls of Han Chinese ancestry. Furthermore, we conducted additional analyses based on the results in the discovery stage. The combined analysis confirmed evidence of genome-wide significant associations in the Han Chinese population for three loci, at 2p16.1 (rs1051061, in an exon of VRK2, P=1.14 × 10 -12 , odds ratio (OR)=1.17), 6p22.1 (rs115070292 in an intron of GABBR1, P=4.96 × 10 -10 , OR=0.77) and 10q24.32 (rs10883795 in an intron of AS3MT, P=7.94 × 10 -10 , OR=0.87; rs10883765 at an intron of ARL3, P=3.06 × 10 -9 , OR=0.87). The polygenic risk score based on Psychiatric Genomics Consortium schizophrenia GWAS data modestly predicted case-control status in the Chinese population (Nagelkerke R 2 : 1.7% ~5.7%). Our pathway analysis suggested that neurological biological pathways such as GABAergic signaling, dopaminergic signaling, cell adhesion molecules and myelination pathways are involved in schizophrenia. These findings provide new insights into the pathogenesis of schizophrenia in the Han Chinese population. Further studies are needed to establish the biological context and potential clinical utility of these findings.

76 FR 50268 - Croscill Acquisition, LLC, Currently Known as Croscill Home, LLC, Plant No. 8, Including On-Site...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-12

..., Currently Known as Croscill Home, LLC, Plant No. 8, Including On-Site Leased Workers From Ex-Cell Home... Fashions, a subsidiary of Croscill, Inc., Plant No. 8, Oxford, North Carolina. The notice was published in... January 14, 2011 (76 FR 2713). The workers are engaged in warehousing and distribution services of...

78 FR 21215 - Energy Conservation Program for Consumer Products: Association of Home Appliance Manufacturers...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-10

... to amend the test procedures for residential dishwashers, dehumidifiers, and conventional cooking... procedures for residential dishwashers, dehumidifiers, and conventional cooking products, go to the Federal e..., dehumidifiers, and conventional cooking products (77 FR 65942, Oct. 31, 2012) and its direct final rule to amend...

24 CFR 3286.102 - Information provided by manufacturer.

Code of Federal Regulations, 2010 CFR

2010-04-01

... HOUSING AND URBAN DEVELOPMENT MANUFACTURED HOME INSTALLATION PROGRAM Certification of Installation in HUD-Administered States § 3286.102 Information provided by manufacturer. (a) Shipment of home to retailer or distributor. At the time the manufactured home is shipped to a retailer or distributor, the manufacturer must...

Analysis of human papilloma virus in oral squamous cell carcinoma using p16: An immunohistochemical study

PubMed Central

Patil, S.; Rao, R. S.; Amrutha, N.; Sanketh, D. S.

2014-01-01

Aims: The aim of this study is to evaluate the expression of human papilloma virus (HPV) in oral squamous cell carcinoma (OSCC) and to correlate the association of HPV in histological grades of OSCC using p16 (p16INK4a) immunohistochemistry (IHC). Subjects and Methods: This study consists of 30 histological diagnosed cases of OSCC (10-well-differentiated oral squamous cell carcinoma [WDOSCC], 10-moderately differentiated oral squamous cell carcinoma [MDOSCC] and 10-poorly differentiated oral squamous cell carcinoma [PDOSCC]). The sections were subjected to IHC procedure using p16. Two parameters in immunohistochemical p16 expression were evaluated by 3 observers based on the criteria by Galgano M. Tetal (2010) (a) percentage of p16 positive cases (b) pattern of p16 staining in various grades of OSCC. Statistical Analysis Used: Kappa test. Results: Totally, 30 samples of 0SCC, p16 positivity was noted in 26/30 (86.66%). Of 26 positive cases, p16 staining was positive in 7/10 (70%) of WDOSCC, 9/10 (90%) in MDOSCC and, 10/10 (100%) PDOSCC. Incidentally, we also found single dispersed cell staining in WDOSCC, patchy staining in MDOSCC and more diffuse staining pattern predominant in PDOSCC. Conclusions: Our study revealed an association between HPV and OSCC. Diffuse staining pattern was noted in PDOSCC, which in turn depicts the increase viral overload, which might have an influence on its aggressive behavior. PMID:24818098

24 CFR 3280.404 - Standard for egress windows and devices for use in manufactured homes.

Code of Federal Regulations, 2011 CFR

2011-04-01

... interior pressure tests for components and cladding must be conducted at the design wind loads required by... in high wind areas. For homes designed to be located in Wind Zones II and III, manufacturers shall... egress window openings. This method must be capable of resisting the design wind pressures specified in...

24 CFR 3280.404 - Standard for egress windows and devices for use in manufactured homes.

Code of Federal Regulations, 2012 CFR

2012-04-01

... interior pressure tests for components and cladding must be conducted at the design wind loads required by... in high wind areas. For homes designed to be located in Wind Zones II and III, manufacturers shall... egress window openings. This method must be capable of resisting the design wind pressures specified in...

24 CFR 3280.404 - Standard for egress windows and devices for use in manufactured homes.

Code of Federal Regulations, 2013 CFR

2013-04-01

... interior pressure tests for components and cladding must be conducted at the design wind loads required by... in high wind areas. For homes designed to be located in Wind Zones II and III, manufacturers shall... egress window openings. This method must be capable of resisting the design wind pressures specified in...

24 CFR 3280.405 - Standard for swinging exterior passage doors for use in manufactured homes.

Code of Federal Regulations, 2010 CFR

2010-04-01

... pre-production specimen test in accordance with AAMA 1702.2-95, Voluntary Standard Swinging Exterior... requirements. The design and construction of exterior door units must meet all requirements of AAMA 1702.2-95.... For homes designed to be located in Wind Zones II and III, manufacturers shall design exterior walls...

24 CFR 3280.405 - Standard for swinging exterior passage doors for use in manufactured homes.

Code of Federal Regulations, 2013 CFR

2013-04-01

... pre-production specimen test in accordance with AAMA 1702.2-95, Voluntary Standard Swinging Exterior... requirements. The design and construction of exterior door units must meet all requirements of AAMA 1702.2-95.... For homes designed to be located in Wind Zones II and III, manufacturers shall design exterior walls...

24 CFR 3280.405 - Standard for swinging exterior passage doors for use in manufactured homes.

Code of Federal Regulations, 2011 CFR

2011-04-01

... pre-production specimen test in accordance with AAMA 1702.2-95, Voluntary Standard Swinging Exterior... requirements. The design and construction of exterior door units must meet all requirements of AAMA 1702.2-95.... For homes designed to be located in Wind Zones II and III, manufacturers shall design exterior walls...

24 CFR 3280.405 - Standard for swinging exterior passage doors for use in manufactured homes.

Code of Federal Regulations, 2012 CFR

2012-04-01

... pre-production specimen test in accordance with AAMA 1702.2-95, Voluntary Standard Swinging Exterior... requirements. The design and construction of exterior door units must meet all requirements of AAMA 1702.2-95.... For homes designed to be located in Wind Zones II and III, manufacturers shall design exterior walls...

24 CFR 3280.405 - Standard for swinging exterior passage doors for use in manufactured homes.

Code of Federal Regulations, 2014 CFR

2014-04-01

... pre-production specimen test in accordance with AAMA 1702.2-95, Voluntary Standard Swinging Exterior... requirements. The design and construction of exterior door units must meet all requirements of AAMA 1702.2-95.... For homes designed to be located in Wind Zones II and III, manufacturers shall design exterior walls...

38 CFR 36.4251 - Loans to finance the purchase of manufactured homes and the cost of necessary site preparation.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Loans to finance the purchase of manufactured homes and the cost of necessary site preparation. 36.4251 Section 36.4251 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) LOAN GUARANTY Guaranty of Loans to Veterans to Purchase Manufactured...

Field Evaluation of Four Novel Roof Designs for Energy-Efficient Manufactured Homes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Levy, E.; Dentz, J.; Ansanelli, E.

2015-12-03

"9A five-bay roof test structure was built, instrumented and monitored in an effort to determine through field testing and analysis the relative contributions of select technologies toward reducing energy use in new manufactured homes. The roof structure in Jamestown, California was designed to examine how differences in roof construction impact space conditioning loads, wood moisture content and attic humidity levels. Conclusions are drawn from the data on the relative energy and moisture performance of various configurations of vented and sealed attics.

Field Evaluation of Four Novel Roof Designs for Energy-Efficient Manufactured Homes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Levy, E.; Dentz, J.; Ansanelli, E.

2015-12-01

A five-bay roof test structure was built, instrumented and monitored in an effort to determine through field testing and analysis the relative contributions of select technologies toward reducing energy use in new manufactured homes. The roof structure in Jamestown, California was designed to examine how differences in roof construction impact space conditioning loads, wood moisture content and attic humidity levels. Conclusions are drawn from the data on the relative energy and moisture performance of various configurations of vented and sealed attics.

10 CFR 71.16 - [Reserved

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false [Reserved] 71.16 Section 71.16 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) PACKAGING AND TRANSPORTATION OF RADIOACTIVE MATERIAL Exemptions § 71.16 [Reserved] ...

77 FR 76952 - Energy Conservation Program for Consumer Products: Association of Home Appliance Manufacturers...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-31

... conventional cooking products, published on October 31, 2012, and DOE's direct final rule to amend energy... cooking products (77 FR 65942 (Oct. 31, 2012)) and its direct final rule to amend the energy conservation... Residential Dishwashers, Dehumidifiers, and Conventional Cooking Products and Docket No. EERE-2011-BT-STD-0060...

Expression of cdk4 and p16 in Oral Lichen Planus.

PubMed

Goel, Sinny; Khurana, Nita; Marwah, Akanksha; Gupta, Sunita

2015-01-01

The purpose of this study was to evaluate the expression of cdk4 and p16, the proteins implicated in hyperproliferation and arrest in oral lichen planus and to compare their expression in erosive and non-erosive oral lichen planus and with normal mucosa and oral squamous cell carcinoma. Analysis of cdk4 and p16 expression was done in 43 erosive oral lichen planus (EOLP) and 17 non-erosive oral lichen planus (NOLP) cases, 10 normal mucosa and 10 oral squamous cell carcinoma (OSCC) cases with immunohistochemistry. This study demonstrated a significantly increased expression of cytoplasmic cdk4 (80% cases, cells stained - 19.6%), and cytoplasmic p16 (68.3% cases, cells stained - 16.4%) in oral lichen planus (OLP) compared to normal mucosa. cdk4 was much higher in OSCC in both cytoplasm and nuclei compared to normal mucosa. Also, while comparing OLP with positive control, significant difference was noted for cdk4 and p16, with expression being more in OSCC. While comparing EOLP with NOLP; significant differences were seen for cdk4 cytoplasmic staining only, for number of cases with positive staining as well as number of cells stained. Overexpression of cytoplasmic cdk4 and p16 was registered in oral lichen planus, however considerably lower than in squamous cell carcinoma. Erosive oral lichen planus demonstrated overexpression of cytoplasmic cdk4 and premalignant nature compared to non-erosive lesion. Therefore there is an obvious possibility for cytoplasmic expression of cdk4 and p16 to predict malignant potential of oral lichen planus lesions.

A Complex Molecular Interplay of Auxin and Ethylene Signaling Pathways Is Involved in Arabidopsis Growth Promotion by Burkholderia phytofirmans PsJN

PubMed Central

Poupin, María J.; Greve, Macarena; Carmona, Vicente; Pinedo, Ignacio

2016-01-01

Modulation of phytohormones homeostasis is one of the proposed mechanisms to explain plant growth promotion induced by beneficial rhizobacteria (PGPR). However, there is still limited knowledge about the molecular signals and pathways underlying these beneficial interactions. Even less is known concerning the interplay between phytohormones in plants inoculated with PGPR. Auxin and ethylene are crucial hormones in the control of plant growth and development, and recent studies report an important and complex crosstalk between them in the regulation of different plant developmental processes. The objective of this work was to study the role of both hormones in the growth promotion of Arabidopsis thaliana plants induced by the well-known PGPR Burkholderia phytofirmans PsJN. For this, the spatiotemporal expression patterns of several genes related to auxin biosynthesis, perception and response and ethylene biosynthesis were studied, finding that most of these genes showed specific transcriptional regulations after inoculation in roots and shoots. PsJN-growth promotion was not observed in Arabidopsis mutants with an impaired ethylene (ein2-1) or auxin (axr1–5) signaling. Even, PsJN did not promote growth in an ethylene overproducer (eto2), indicating that a fine regulation of both hormones signaling and homeostasis is necessary to induce growth of the aerial and root tissues. Auxin polar transport is also involved in growth promotion, since PsJN did not promote primary root growth in the pin2 mutant or under chemical inhibition of transport in wild type plants. Finally, a key role for ethylene biosynthesis was found in the PsJN-mediated increase in root hair number. These results not only give new insights of PGPR regulation of plant growth but also are also useful to understand key aspects of Arabidopsis growth control. PMID:27148317

Meiotic and pedigree segregation analyses in carriers of t(4;8)(p16;p23.1) differing in localization of breakpoint positions at 4p subband 4p16.3 and 4p16.1.

PubMed

Midro, Alina T; Zollino, Marcella; Wiland, Ewa; Panasiuk, Barbara; Iwanowski, Piotr S; Murdolo, Marina; Śmigiel, Robert; Sąsiadek, Maria; Pilch, Jacek; Kurpisz, Maciej

2016-02-01

The purpose of this study was to compare meiotic segregation in sperm cells from two carriers with t(4;8)(p16;p23.1) reciprocal chromosome translocations (RCTs), differing in localization of the breakpoint positions at the 4p subband-namely, 4p16.3 (carrier 1) and 4p16.1 (carrier 2)-and to compare data of the pedigree analyses performed by direct method. Three-color fluorescent in situ hybridization (FISH) on sperm cells and FISH mapping for the evaluation of the breakpoint positions, data from pedigrees, and direct segregation analysis of the pedigrees were performed. Similar proportions of normal/balanced and unbalanced sperm cells were found in both carriers. The most common was an alternate type of segregation (about 52 % and about 48 %, respectively). Unbalanced adjacent I and adjacent II karyotypes were found in similar proportions about 15 %. The direct segregation analysis (following Stengel-Rutkowski) of the pedigree of carriers of t(4;8)(p16.1;p23.1) was performed and results were compared with the data of the pedigree segregation analysis obtained earlier through the indirect method. The probability of live-born progeny with unbalanced karyotype for carriers of t(4;8)(p16.1;p23.1) was moderately high at 18.8 %-comparable to the value obtained using the indirect method for the same carriership, which was 12 %. This was, however, markedly lower than the value of 41.2 % obtained through the pedigree segregation indirect analysis estimated for carriers of t(4;8)(p16.3;p23.1), perhaps due to the unique composition of genes present within the 4p16.1-4p 16.3 region. Revealed differences in pedigree segregation analysis did not correspond to the very similar profile of meiotic segregation patterns presented by carrier 1 and carrier 2. Most probably, such discordances may be due to differences in embryo survival rates arising from different genetic backgrounds.

Effects of the plant growth-promoting bacterium Burkholderia phytofirmans PsJN throughout the life cycle of Arabidopsis thaliana.

PubMed

Poupin, María Josefina; Timmermann, Tania; Vega, Andrea; Zuñiga, Ana; González, Bernardo

2013-01-01

Plant growth-promoting rhizobacteria (PGPR) induce positive effects in plants, such as increased growth or reduced stress susceptibility. The mechanisms behind PGPR/plant interaction are poorly understood, as most studies have described short-term responses on plants and only a few studies have analyzed plant molecular responses under PGPR colonization. Here, we studied the effects of the PGPR bacterial model Burkholderiaphytofirmans PsJN on the whole life cycle of Arabidopsis thaliana plants. We reported that at different plant developmental points, strain PsJN can be found in the rhizosphere and also colonizing their internal tissues. In early ontogeny, strain PsJN increased several growth parameters and accelerated growth rate of the plants. Also, an Arabidopsis transcriptome analysis revealed that 408 genes showed differential expression in PsJN-inoculated plants; some of these genes are involved in stress response and hormone pathways. Specifically, genes implicated in auxin and gibberellin pathways were induced. Quantitative transcriptional analyses of selected genes in different developmental stages revealed that the beginning of these changes could be evidenced early in development, especially among the down-regulated genes. The inoculation with heat-killed bacteria provoked a more severe transcriptional response in plants, but was not able to induce plant growth-promotion. Later in ontogeny, the growth rates of inoculated plants decreased with respect to the non-inoculated group and, interestingly, the inoculation accelerated the flowering time and the appearance of senescence signs in plants; these modifications correlate with the early up-regulation of flowering control genes. Then, we show that a single inoculation with a PGPR could affect the whole life cycle of a plant, accelerating its growth rate and shortening its vegetative period, both effects relevant for most crops. Thus, these findings provide novel and interesting aspects of these relevant

24 CFR 3280.404 - Standard for egress windows and devices for use in manufactured homes.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 5 2010-04-01 2010-04-01 false Standard for egress windows and... SAFETY STANDARDS Testing § 3280.404 Standard for egress windows and devices for use in manufactured homes..., construction, and installation of windows and approved devices intended to be used as an emergency exit during...

75 FR 12730 - Foreign-Trade Zone 158-Vicksburg/Jackson, MS; Amendment to Application for Subzone; Max Home, LLC...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-17

...-purpose subzone status for the upholstered furniture manufacturing facilities of Max Home, LLC (Max Home... additional manufacturing plant and warehouse (100 employees/ 26 acres/160,000 sq. ft.) are located at 1313... finished upholstered furniture (chairs, seats, sofas, sleep sofas, and sectionals). The additional...

78 FR 34120 - Endangered Species; Marine Mammals; Issuance of Permits

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-06

...; August 27, October 31, 2012. 2012. 704654 Scovill Zoo 77 FR 51819; August 27, October 31, 2012. 2012... Cincinnati Zoo & Botanical 77 FR 61627; October 10, November 16, 2012. Garden. 2012. 679042 Duke Lemur Center... Simon Ranch LLC 77 FR 61627; October 10, November 16, 2012. 2012. 819063 Tautphaus Park Zoo........ 77...

75 FR 51016 - Sunshine Act Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-18

... COMMODITY FUTURES TRADING COMMISSION Sunshine Act Meetings Time and Date: 11 a.m., Friday September 17, 2010. Place: 1155 21st St., NW., Washington, DC, 9th Floor Commission Conference Room. Status.... [FR Doc. 2010-20600 Filed 8-16-10; 4:15 pm] BILLING CODE 6351-01-P ...

75 FR 51016 - Sunshine Act Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-18

... COMMODITY FUTURES TRADING COMMISSION Sunshine Act Meetings TIME AND DATE: 11 a.m., Friday September 24, 2010. PLACE: 1155 21st St., NW., Washington, DC, 9th Floor Commission Conference Room. STATUS.... [FR Doc. 2010-20605 Filed 8-16-10; 4:15 pm] BILLING CODE 6351-01-P ...

75 FR 51016 - Sunshine Act Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-18

... COMMODITY FUTURES TRADING COMMISSION Sunshine Act Meetings TIME AND DATE: 11 a.m., Friday September 3, 2010. PLACE: 1155 21st St., NW., Washington, DC, 9th Floor Commission Conference Room. STATUS.... [FR Doc. 2010-20597 Filed 8-16-10; 4:15 pm] BILLING CODE 6351-01-P ...

75 FR 35901 - On-Site Completion of Construction of Manufactured Homes

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-23

... may access this number via TTY by calling the Federal Information Relay Service at 800-877-8339... the toll-free Federal Information Relay Service at 1-800-877-8339. SUPPLEMENTARY INFORMATION: I... report also must be submitted to the State Administrative Agencies (SAAs) of the states where the home is...

27 CFR 16.10 - Meaning of terms.

Code of Federal Regulations, 2011 CFR

2011-04-01

... State statutes, regulations and principles and rules having the force of law. TTB. The Alcohol and... and used in this part shall have the same meaning as assigned to it by the Act. [T.D. ATF-294, 55 FR 5421, Feb. 14, 1990, as amended by T.D. ATF-425, 65 FR 11892, Mar. 7, 2000; T.D. TTB-44, 71 FR 16925...

27 CFR 16.10 - Meaning of terms.

Code of Federal Regulations, 2010 CFR

2010-04-01

... State statutes, regulations and principles and rules having the force of law. TTB. The Alcohol and... and used in this part shall have the same meaning as assigned to it by the Act. [T.D. ATF-294, 55 FR 5421, Feb. 14, 1990, as amended by T.D. ATF-425, 65 FR 11892, Mar. 7, 2000; T.D. TTB-44, 71 FR 16925...

16 CFR 309.10 - Alternative vehicle fuel rating.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Electricity) and of Manufacturers of Electric Vehicle Fuel Dispensing Systems § 309.10 Alternative vehicle.../code_of_federal_regulations/ibr_locations.html. (b) If you are a manufacturer of electric vehicle fuel... electric vehicle fuel dispensing system, you must possess a reasonable basis, consisting of competent and...

40 CFR 457.10 - Applicability; description of the commercial manufacture of explosives subcategory.

Code of Federal Regulations, 2010 CFR

2010-07-01

... commercial manufacture of explosives subcategory. 457.10 Section 457.10 Protection of Environment... SOURCE CATEGORY Manufacture of Explosives Subcategory § 457.10 Applicability; description of the commercial manufacture of explosives subcategory. The provisions of this subpart are applicable to discharges...

16 CFR § 1102.12 - Manufacturer comments.

Code of Federal Regulations, 2013 CFR

2013-01-01

... PUBLICLY AVAILABLE CONSUMER PRODUCT SAFETY INFORMATION DATABASE Content Requirements § 1102.12 Manufacturer... Database if such manufacturer comment meets the following requirements: (1) Manufacturer comment relates to... publication in the Database. (2) Unique identifier. A manufacturer comment must state the unique identifier...

76 FR 34781 - Sunshine Act Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-14

... discussions on Thursday, June 16, 2011 at the CFTC's headquarters at Three Lafayette Centre, 1155 21st Street... the meeting includes panel discussions concerning the definitions of ``swap dealer,'' ``security-based.... Elizabeth M. Murphy, Secretary. [FR Doc. 2011-14783 Filed 6-10-11; 11:15 am] BILLING CODE 8011-01-P ...

10 CFR 707.16 - Records.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 4 2013-01-01 2013-01-01 false Records. 707.16 Section 707.16 Energy DEPARTMENT OF ENERGY WORKPLACE SUBSTANCE ABUSE PROGRAMS AT DOE SITES Procedures § 707.16 Records. (a) Confirmed positive test...) Contractors shall maintain maximum confidentiality of records related to illegal drug use, to the extent...

24 CFR 3282.409 - Manufacturer's plan for notification and correction.

Code of Federal Regulations, 2010 CFR

2010-04-01

... homes; (4) Inspection of the design of the manufactured home in question to determine whether the... COMMISSIONER, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT MANUFACTURED HOME PROCEDURAL AND ENFORCEMENT... identifying criteria, all manufactured homes with respect to which notification is to be provided. The class...

50 CFR Figure 16 to Part 679 - Bering Sea Habitat Conservation Area

Code of Federal Regulations, 2014 CFR

2014-10-01

... 50 Wildlife and Fisheries 13 2014-10-01 2014-10-01 false Bering Sea Habitat Conservation Area 16 Figure 16 to part 679 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND... ALASKA Pt. 679, Fig. 16 Figure 16 to part 679—Bering Sea Habitat Conservation Area ER25JY08.010 [73 FR...

50 CFR Figure 16 to Part 679 - Bering Sea Habitat Conservation Area

Code of Federal Regulations, 2012 CFR

2012-10-01

... 50 Wildlife and Fisheries 13 2012-10-01 2012-10-01 false Bering Sea Habitat Conservation Area 16 Figure 16 to part 679 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND... ALASKA Pt. 679, Fig. 16 Figure 16 to part 679—Bering Sea Habitat Conservation Area ER25JY08.010 [73 FR...

50 CFR Figure 16 to Part 679 - Bering Sea Habitat Conservation Area

Code of Federal Regulations, 2010 CFR

2010-10-01

... 50 Wildlife and Fisheries 9 2010-10-01 2010-10-01 false Bering Sea Habitat Conservation Area 16 Figure 16 to part 679 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND... ALASKA Pt. 679, Fig. 16 Figure 16 to part 679—Bering Sea Habitat Conservation Area ER25JY08.010 [73 FR...

50 CFR Figure 16 to Part 679 - Bering Sea Habitat Conservation Area

Code of Federal Regulations, 2011 CFR

2011-10-01

... 50 Wildlife and Fisheries 11 2011-10-01 2011-10-01 false Bering Sea Habitat Conservation Area 16 Figure 16 to part 679 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND... ALASKA Pt. 679, Fig. 16 Figure 16 to part 679—Bering Sea Habitat Conservation Area ER25JY08.010 [73 FR...

50 CFR Figure 16 to Part 679 - Bering Sea Habitat Conservation Area

Code of Federal Regulations, 2013 CFR

2013-10-01

... 50 Wildlife and Fisheries 13 2013-10-01 2013-10-01 false Bering Sea Habitat Conservation Area 16 Figure 16 to part 679 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND... ALASKA Pt. 679, Fig. 16 Figure 16 to part 679—Bering Sea Habitat Conservation Area ER25JY08.010 [73 FR...

21 CFR 1140.10 - General responsibilities of manufacturers, distributors, and retailers.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 8 2012-04-01 2012-04-01 false General responsibilities of manufacturers, distributors, and retailers. 1140.10 Section 1140.10 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF... ensuring that the cigarettes or smokeless tobacco it manufactures, labels, advertises, packages...

21 CFR 1140.10 - General responsibilities of manufacturers, distributors, and retailers.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 8 2013-04-01 2013-04-01 false General responsibilities of manufacturers, distributors, and retailers. 1140.10 Section 1140.10 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF... ensuring that the cigarettes or smokeless tobacco it manufactures, labels, advertises, packages...

21 CFR 1140.10 - General responsibilities of manufacturers, distributors, and retailers.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 8 2014-04-01 2014-04-01 false General responsibilities of manufacturers, distributors, and retailers. 1140.10 Section 1140.10 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF... ensuring that the cigarettes or smokeless tobacco it manufactures, labels, advertises, packages...

21 CFR 1140.10 - General responsibilities of manufacturers, distributors, and retailers.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 8 2011-04-01 2011-04-01 false General responsibilities of manufacturers, distributors, and retailers. 1140.10 Section 1140.10 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF... ensuring that the cigarettes or smokeless tobacco it manufactures, labels, advertises, packages...

10 CFR 16.9 - Hearing.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 1 2014-01-01 2014-01-01 false Hearing. 16.9 Section 16.9 Energy NUCLEAR REGULATORY... § 16.9 Hearing. (a) Request for hearing. (1) An employee shall file a petition for a hearing in... creditor agency, a hearing may be requested by filing a written petition stating why the employee disputes...

10 CFR 707.16 - Records.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 4 2014-01-01 2014-01-01 false Records. 707.16 Section 707.16 Energy DEPARTMENT OF ENERGY WORKPLACE SUBSTANCE ABUSE PROGRAMS AT DOE SITES Procedures § 707.16 Records. (a) Confirmed positive test results shall be provided to the Medical Review Officer and other contractor and DOE officials with a need...

10 CFR 707.16 - Records.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Records. 707.16 Section 707.16 Energy DEPARTMENT OF ENERGY WORKPLACE SUBSTANCE ABUSE PROGRAMS AT DOE SITES Procedures § 707.16 Records. (a) Confirmed positive test results shall be provided to the Medical Review Officer and other contractor and DOE officials with a need...

10 CFR 16.9 - Hearing.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 1 2010-01-01 2010-01-01 false Hearing. 16.9 Section 16.9 Energy NUCLEAR REGULATORY... § 16.9 Hearing. (a) Request for hearing. (1) An employee shall file a petition for a hearing in... creditor agency, a hearing may be requested by filing a written petition stating why the employee disputes...

Extracts containing CLPs of Bacillus amyloliquefaciens JN68 isolated from chicken intestines exert antimicrobial effects, particularly on methicillin-resistant Staphylococcus aureus and Listeria monocytogenes.

PubMed

Chen, Jen-Ni; Wei, Chyou-Wei; Liu, Hsiao-Chun; Chen, Shu-Ying; Chen, Chinshuh; Juang, Yu-Min; Lai, Chien-Chen; Yiang, Giou-Teng

2016-12-01

Bacillus amyloliquefaciens JN68, which has been discussed with regards to its antimicrobial activities, was successfully isolated from healthy chicken intestines in the present study. Using the spot-on-the-lawn antagonism method, the preliminary study indicated that a suspension culture of the B. amyloliquefaciens JN68 strain can inhibit the growth of Aspergillus niger and Penicillium pinophilum. Furthermore, the cyclic lipopeptides (CLPs) produced by the B. amyloliquefaciens JN68 strain were further purified through acid precipitation and Bond Elut®C18 chromatography, and their structures were identified using the liquid chromatography‑electrospray ionization‑mass spectrometry (MS)/MS method. Purified CLPs exerted broad spectrum antimicrobial activities on various pathogenic and foodborne bacteria and fungi, as determined using the agar well diffusion method. Listeria monocytogenes can induce listeriosis, which is associated with a high mortality rate. Methicillin‑resistant Staphylococcus aureus (MRSA) is a major pathogenic bacteria that causes nosocomial infections. Therefore, L. monocytogenes and MRSA are currently of great concern. The present study aimed to determine whether B. amyloliquefaciens JN68 extracts could inhibit L. monocytogenes and MRSA. The results indicated that extracts of B. amyloliquefaciens JN68 have CLP components, and can successfully inhibit the growth of L. monocytogenes and MRSA.

Calcitonin gene-related peptide cooperates with substance P to inhibit melanogenesis and induces apoptosis of B16F10 cells.

PubMed

Zhou, Jia; Feng, Jun-Yi; Wang, Qian; Shang, Jing

2015-07-01

Skin is the largest organ in human body and works as biologically active barrier to provide critical preservation of body homeostasis. The skin is highly innervated by a plenitude of nerve fiber subpopulations, each carrying one or more neuronal mediators. Melanocyte itself also intimately contact with nerve fibers to form 'synaptic-like structure' and its functions may be directly regulated by the mediators contained in terminals of intra-epidermal nerve fibers. Clinical and biochemical studies have suggested that calcitonin gene-related peptide (CGRP) is involved in vitiligo skin. The present study was designed to investigate the effect of CGRP on epidermal melanocytes. After treatment with CGRP ranging from 0 to 500 ng/mL for 48 h, tyrosinase activity and melanogenesis were with little changes compared to treatment with medium only in B16F10 cells. Treatment with 500 ng/mL of CGRP cooperates with substance P (SP) (0.1-10 nM) to decrease tyrosinase activity and decrease melanin biosynthesis in B16F10 cells in a concentration-dependent manner. Furthermore, CGRP (8-37) antagonizes the synergistic effect of CGRP. The effect of CGRP on the cell apoptosis was examined. Treatments with 0-500 ng/mL of CGRP for 24 h, the expression levels of cleaved caspase-3, total caspase-3, cleaved caspase-9 and total caspase-9 were increased in a concentration-dependent manner. And 500 ng/mL of CGRP induced B16F10 cell apoptosis showed by TUNEL assay. In addition, Bax expression was up-regulated and Bcl-2 down-regulated in response to CGRP treatment. Hence, the Bax/Bcl-2 ratio was significantly increased. These in vitro observations indicate the pro-apoptotic impact of CGRP on B16F10 cell. Copyright © 2015 Elsevier Ltd. All rights reserved.

10 CFR 611.202 - Advanced Technology Vehicle Manufacturing Facility Award Program.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Advanced Technology Vehicle Manufacturing Facility Award... TECHNOLOGY VEHICLES MANUFACTURER ASSISTANCE PROGRAM Facility/Funding Awards § 611.202 Advanced Technology Vehicle Manufacturing Facility Award Program. DOE may issue, under the Advanced Technology Vehicle...

10 CFR 611.202 - Advanced Technology Vehicle Manufacturing Facility Award Program.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 4 2014-01-01 2014-01-01 false Advanced Technology Vehicle Manufacturing Facility Award... TECHNOLOGY VEHICLES MANUFACTURER ASSISTANCE PROGRAM Facility/Funding Awards § 611.202 Advanced Technology Vehicle Manufacturing Facility Award Program. DOE may issue, under the Advanced Technology Vehicle...

10 CFR 611.202 - Advanced Technology Vehicle Manufacturing Facility Award Program.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 4 2012-01-01 2012-01-01 false Advanced Technology Vehicle Manufacturing Facility Award... TECHNOLOGY VEHICLES MANUFACTURER ASSISTANCE PROGRAM Facility/Funding Awards § 611.202 Advanced Technology Vehicle Manufacturing Facility Award Program. DOE may issue, under the Advanced Technology Vehicle...

10 CFR 611.202 - Advanced Technology Vehicle Manufacturing Facility Award Program.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Advanced Technology Vehicle Manufacturing Facility Award... TECHNOLOGY VEHICLES MANUFACTURER ASSISTANCE PROGRAM Facility/Funding Awards § 611.202 Advanced Technology Vehicle Manufacturing Facility Award Program. DOE may issue, under the Advanced Technology Vehicle...

10 CFR 611.202 - Advanced Technology Vehicle Manufacturing Facility Award Program.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 4 2013-01-01 2013-01-01 false Advanced Technology Vehicle Manufacturing Facility Award... TECHNOLOGY VEHICLES MANUFACTURER ASSISTANCE PROGRAM Facility/Funding Awards § 611.202 Advanced Technology Vehicle Manufacturing Facility Award Program. DOE may issue, under the Advanced Technology Vehicle...

Microduplications of 16p11.2 are Associated with Schizophrenia

PubMed Central

McCarthy, Shane; Makarov, Vladimir; Kirov, George; Addington, Anjene; McClellan, Jon; Yoon, Seungtai; Perkins, Dianna; Dickel, Diane E.; Kusenda, Mary; Krastoshevsky, Olga; Krause, Verena; Kumar, Ravinesh A.; Grozeva, Detelina; Malhotra, Dheeraj; Walsh, Tom; Zackai, Elaine H.; Kaplan, Paige; Ganesh, Jaya; Krantz, Ian D.; Spinner, Nancy B.; Roccanova, Patricia; Bhandari, Abhishek; Pavon, Kevin; Lakshmi, B.; Leotta, Anthony; Kendall, Jude; Lee, Yoon-ha; Vacic, Vladimir; Gary, Sydney; Iakoucheva, Lilia; Crow, Timothy J.; Christian, Susan L.; Lieberman, Jeffrey; Stroup, Scott; Lehtimäki, Terho; Puura, Kaija; Haldeman-Englert, Chad; Pearl, Justin; Goodell, Meredith; Willour, Virginia L.; DeRosse, Pamela; Steele, Jo; Kassem, Layla; Wolff, Jessica; Chitkara, Nisha; McMahon, Francis J.; Malhotra, Anil K.; Potash, James B.; Schulze, Thomas G.; Nöthen, Markus M.; Cichon, Sven; Rietschel, Marcella; Leibenluft, Ellen; Kustanovich, Vlad; Lajonchere, Clara M.; Sutcliffe, James S.; Skuse, David; Gill, Michael; Gallagher, Louise; Mendell, Nancy R.; Craddock, Nick; Owen, Michael J.; O’Donovan, Michael C.; Shaikh, Tamim H.; Susser, Ezra; DeLisi, Lynn E.; Sullivan, Patrick F.; Deutsch, Curtis K.; Rapoport, Judith; Levy, Deborah L.; King, Mary-Claire; Sebat, Jonathan

2010-01-01

Recurrent microdeletions and microduplications of a 600 kb genomic region of chromosome 16p11.2 have been implicated in childhood-onset developmental disorders1-3. Here we report the strong association of 16p11.2 microduplications with schizophrenia in two large cohorts. In the primary sample, the microduplication was detected in 12/1906 (0.63%) cases and 1/3971 (0.03%) controls (P=1.2×10-5, OR=25.8). In the replication sample, the microduplication was detected in 9/2645 (0.34%) cases and 1/2420 (0.04%) controls (P=0.022, OR=8.3). For the series combined, microduplication of 16p11.2 was associated with 14.5-fold increased risk of schizophrenia (95% C.I. [3.3, 62]). A meta-analysis of multiple psychiatric disorders showed a significant association of the microduplication with schizophrenia, bipolar disorder and autism. The reciprocal microdeletion was associated only with autism and developmental disorders. Analysis of patient clinical data showed that head circumference was significantly larger in patients with the microdeletion compared with patients with the microduplication (P = 0.0007). Our results suggest that the microduplication of 16p11.2 confers substantial risk for schizophrenia and other psychiatric disorders, whereas the reciprocal microdeletion is associated with contrasting clinical features. PMID:19855392

Effects of the tripeptide substance P antagonist, FR113680, on airway constriction and airway edema induced by neurokinins in guinea-pigs.

PubMed

Murai, M; Morimoto, H; Maeda, Y; Fujii, T

1992-06-24

FR113680 is a newly developed tripeptide substance P (SP) receptor antagonist. The effects of FR113680 on airway constriction and airway edema induced by neurokinins were investigated in guinea-pigs. In in vitro experiments, FR113680 inhibited the contraction of isolated guinea-pig trachea induced by SP and neurokinin A (NKA) in a dose-dependent manner with IC50 values of 2.3 x 10(-6) and 1.5 x 10(-5) M, respectively. The tracheal contraction induced by histamine and acetylcholine was not affected by FR113680. FR113680 (5 x 10(-5) M) also significantly inhibited the atropine-resistant contraction of isolated guinea-pig bronchi induced by electrical field stimulation. In in vivo experiments, FR113680 given i.v. inhibited SP-induced airway constriction in guinea-pigs at doses of 1 and 10 mg kg-1. However, FR113680 only inhibited NKA- and capsaicin-induced airway constriction by 40-50% even at a dose of 10 mg kg-1. FR113680 also inhibited SP-induced airway edema in guinea-pigs with the same potency as it inhibited SP-induced airway constriction. Histamine-induced airway constriction and airway edema were not affected at a dose of 10 mg kg-1. These results suggest that FR113680 preferentially inhibits responses induced by NK1 receptor activation (SP-induced airway constriction and airway edema), but is less effective on a NK2 receptor-induced response (airway constriction by NKA and neurogenic stimulation).

40 CFR 52.570 - Identification of plan.

Code of Federal Regulations, 2011 CFR

2011-07-01

...-burning Equipment 7/20/05 2/9/09, 75 FR 6309 391-3-1-.02(2)(e) Particulate Emission from Manufacturing...) Particulate Emission from Asphaltic Concrete Hot Mix Plants 1/17/79 9/18/79, 44 FR 54047 391-3-1-.02(2)(l... 7/10/01, 66 FR 35906 391-3-1-.02(2)(lll) NOX Emissions from Fuel-burning Equipment 2/16/00 7/10/01...

Whitson during Expedition 16 EVA 10/Alpha

NASA Image and Video Library

2007-11-09

ISS016-E-010001 (9 Nov. 2007) --- Astronaut Peggy A. Whitson, Expedition 16 commander, participates in a session of extravehicular activity (EVA) as construction continues on the International Space Station (ISS). During the spacewalk Whitson and cosmonaut Yuri I. Malenchenko (out of frame), flight engineer representing Russia's Federal Space Agency, prepared for the relocation of the Pressurized Mating Adapter 2 (PMA-2) and the subsequent move of the new Harmony node to its permanent ISS home.

Whitson during Expedition 16 EVA 10/Alpha

NASA Image and Video Library

2007-11-09

ISS016-E-009989 (9 Nov. 2007) --- Astronaut Peggy A. Whitson, Expedition 16 commander, participates in a session of extravehicular activity (EVA) as construction continues on the International Space Station (ISS). During the spacewalk Whitson and cosmonaut Yuri I. Malenchenko (out of frame), flight engineer representing Russia's Federal Space Agency, prepared for the relocation of the Pressurized Mating Adapter 2 (PMA-2) and the subsequent move of the new Harmony node to its permanent ISS home.

Malenchenko during Expedition 16 EVA 10/Alpha

NASA Image and Video Library

2007-11-09

ISS016-E-009981 (9 Nov. 2007) --- Cosmonaut Yuri I. Malenchenko, Expedition 16 flight engineer representing Russia's Federal Space Agency, participates in a session of extravehicular activity (EVA) as construction continues on the International Space Station (ISS). During the spacewalk Malenchenko and astronaut Peggy A. Whitson (out of frame), commander, prepared for the relocation of the Pressurized Mating Adapter 2 (PMA-2) and the subsequent move of the new Harmony node to its permanent ISS home.

24 CFR 3282.406 - Required manufacturer correction.

Code of Federal Regulations, 2010 CFR

2010-04-01

... hazard or serious defect that can be related to an error in design or assembly of the manufactured home by the manufacturer, including an error in design or assembly of any component or system incorporated... HOUSING AND URBAN DEVELOPMENT MANUFACTURED HOME PROCEDURAL AND ENFORCEMENT REGULATIONS Consumer Complaint...

40 CFR 205.171-10 - Prohibition on distribution in commerce; manufacturer's remedy.

Code of Federal Regulations, 2011 CFR

2011-07-01

... commerce; manufacturer's remedy. 205.171-10 Section 205.171-10 Protection of Environment ENVIRONMENTAL... Motorcycle Exhaust Systems § 205.171-10 Prohibition on distribution in commerce; manufacturer's remedy. (a... distributed into commerce until necessary adjustment or repairs have been made and the exhaust system passes a...

40 CFR 205.171-10 - Prohibition on distribution in commerce; manufacturer's remedy.

Code of Federal Regulations, 2014 CFR

2014-07-01

... commerce; manufacturer's remedy. 205.171-10 Section 205.171-10 Protection of Environment ENVIRONMENTAL... Motorcycle Exhaust Systems § 205.171-10 Prohibition on distribution in commerce; manufacturer's remedy. (a... distributed into commerce until necessary adjustment or repairs have been made and the exhaust system passes a...

40 CFR 205.171-10 - Prohibition on distribution in commerce; manufacturer's remedy.

Code of Federal Regulations, 2013 CFR

2013-07-01

... commerce; manufacturer's remedy. 205.171-10 Section 205.171-10 Protection of Environment ENVIRONMENTAL... Motorcycle Exhaust Systems § 205.171-10 Prohibition on distribution in commerce; manufacturer's remedy. (a... distributed into commerce until necessary adjustment or repairs have been made and the exhaust system passes a...

40 CFR 205.171-10 - Prohibition on distribution in commerce; manufacturer's remedy.

Code of Federal Regulations, 2010 CFR

2010-07-01

... commerce; manufacturer's remedy. 205.171-10 Section 205.171-10 Protection of Environment ENVIRONMENTAL... Motorcycle Exhaust Systems § 205.171-10 Prohibition on distribution in commerce; manufacturer's remedy. (a... distributed into commerce until necessary adjustment or repairs have been made and the exhaust system passes a...

A de-novo interstitial microduplication involving 2p16.1-p15 and mirroring 2p16.1-p15 microdeletion syndrome: Clinical and molecular analysis.

PubMed

Mimouni-Bloch, Aviva; Yeshaya, Josepha; Kahana, Sarit; Maya, Idit; Basel-Vanagaite, Lina

2015-11-01

Microdeletions of various sizes in the 2p16.1-p15 chromosomal region have been grouped together under the 2p16.1-p15 microdeletion syndrome. Children with this syndrome generally share certain features including microcephaly, developmental delay, facial dysmorphism, urogenital and skeletal abnormalities. We present a child with a de-novo interstitial 1665 kb duplication of 2p16.1-p15. Clinical features of this child are distinct from those of children with the 2p16.1-p15 microdeletion syndrome, specifically the head circumference which is within the normal range and mild intellectual disability with absence of autistic behaviors. Microduplications many times bear milder clinical phenotypes in comparison with corresponding microdeletion syndromes. Indeed, as compared to the microdeletion syndrome patients, the 2p16.1-p15 microduplication seems to have a milder cognitive effect and no effect on other body systems. Limited information available in genetic databases about cases with overlapping duplications indicates that they all have abnormal developmental phenotypes. The involvement of genes in this location including BCL11A, USP34 and PEX13, affecting fundamental developmental processes both within and outside the nervous system may explain the clinical features of the individual described in this report. Copyright © 2015 European Paediatric Neurology Society. Published by Elsevier Ltd. All rights reserved.

12 CFR 590.4 - Federally-related residential manufactured housing loans-consumer protection provisions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... first lien on a residential mobile home if a creditor covered by this part complies with the consumer... the final scheduled installment. (g) Deferral fees. (1) With respect to mobile home credit... money order; do not send cash. [54 FR 49715, Nov. 30, 1989, as amended at 61 FR 50984, Sept. 30, 1996...

12 CFR 590.4 - Federally-related residential manufactured housing loans-consumer protection provisions.

Code of Federal Regulations, 2013 CFR

2013-01-01

... first lien on a residential mobile home if a creditor covered by this part complies with the consumer... the final scheduled installment. (g) Deferral fees. (1) With respect to mobile home credit... money order; do not send cash. [54 FR 49715, Nov. 30, 1989, as amended at 61 FR 50984, Sept. 30, 1996...

12 CFR 590.4 - Federally-related residential manufactured housing loans-consumer protection provisions.

Code of Federal Regulations, 2012 CFR

2012-01-01

... first lien on a residential mobile home if a creditor covered by this part complies with the consumer... the final scheduled installment. (g) Deferral fees. (1) With respect to mobile home credit... money order; do not send cash. [54 FR 49715, Nov. 30, 1989, as amended at 61 FR 50984, Sept. 30, 1996...

12 CFR 590.4 - Federally-related residential manufactured housing loans-consumer protection provisions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... first lien on a residential mobile home if a creditor covered by this part complies with the consumer... the final scheduled installment. (g) Deferral fees. (1) With respect to mobile home credit... money order; do not send cash. [54 FR 49715, Nov. 30, 1989, as amended at 61 FR 50984, Sept. 30, 1996...

12 CFR 590.4 - Federally-related residential manufactured housing loans-consumer protection provisions.

Code of Federal Regulations, 2014 CFR

2014-01-01

... first lien on a residential mobile home if a creditor covered by this part complies with the consumer... the final scheduled installment. (g) Deferral fees. (1) With respect to mobile home credit... money order; do not send cash. [54 FR 49715, Nov. 30, 1989, as amended at 61 FR 50984, Sept. 30, 1996...

10 CFR 52.171 - Finality of manufacturing licenses; information requests.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 2 2013-01-01 2013-01-01 false Finality of manufacturing licenses; information requests. 52.171 Section 52.171 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS, AND... manufactured reactor, the costs and benefits of severe accident mitigation design alternatives, and the bases...

10 CFR 52.171 - Finality of manufacturing licenses; information requests.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 2 2011-01-01 2011-01-01 false Finality of manufacturing licenses; information requests. 52.171 Section 52.171 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS, AND... manufactured reactor, the costs and benefits of severe accident mitigation design alternatives, and the bases...

10 CFR 52.171 - Finality of manufacturing licenses; information requests.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 2 2014-01-01 2014-01-01 false Finality of manufacturing licenses; information requests. 52.171 Section 52.171 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS, AND... manufactured reactor, the costs and benefits of severe accident mitigation design alternatives, and the bases...

10 CFR 52.171 - Finality of manufacturing licenses; information requests.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 2 2012-01-01 2012-01-01 false Finality of manufacturing licenses; information requests. 52.171 Section 52.171 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS, AND... manufactured reactor, the costs and benefits of severe accident mitigation design alternatives, and the bases...

The role of human papillomavirus in p16-positive oral cancers.

PubMed

Belobrov, Simone; Cornall, Alyssa M; Young, Richard J; Koo, Kendrick; Angel, Christopher; Wiesenfeld, David; Rischin, Danny; Garland, Suzanne M; McCullough, Michael

2018-01-01

The aim of this study was to identify the presence and frequency of human papillomavirus (HPV) nucleic acid in p16-positive oral squamous cell carcinomas (OSCCs), to assess whether the virus was transcriptionally active and to assess the utility of p16 overexpression as a surrogate marker for HPV in OSCC. Forty-six OSCC patients treated between 2007 and 2011 with available formalin-fixed paraffin-embedded (FFPE) specimens were included. Twenty-three patients were positive for p16 by immunohistochemistry (IHC) and these were matched with 23 patients with p16-negative tumours. Laser capture microdissection of the FFPE OSCC tissues was undertaken to isolate invasive tumour tissue. DNA was extracted and tested for high-risk HPV types using a PCR-ELISA method based on the L1 SPF10 consensus primers, and a real-time PCR method targeting HPV-16 and HPV-18 E6 region. Genotyping of HPV-positive cases was performed using a reverse line blot hybridization assay (Inno-LiPA). RNAScope ® (a chromogenic RNA in situ hybridization assay) was utilized to detect E6/E7 mRNA of known high-risk HPV types for detection of transcriptionally active virus. HPV DNA was found in 3 OSCC cases, all of which were p16 IHC-positive. Two cases were genotyped as HPV-16 and one as HPV-33. Only one of the HPV-16 cases was confirmed to harbour transcriptionally active virus via HPV RNA ISH. We have shown that the presence of transcriptionally active HPV rarely occurs in OSCC and that p16 is not an appropriate surrogate marker for HPV in OSCC cases. We propose that non-viral mechanisms are responsible for the majority of IHC p16 overexpression in OSCC. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Genetics Home Reference: generalized pustular psoriasis

MedlinePlus

... C, Valeyrie-Allanore L, Vicente MA, Trembath RC, Smith CH, Barker JN, Capon F. IL36RN mutations define ... A, Simpson MA, Pink AE, Di Meglio P, Smith CH, Pullabhatla V, Knight J, Spain SL, Nestle ...

P16 UV mutations in human skin epithelial tumors.

PubMed

Soufir, N; Molès, J P; Vilmer, C; Moch, C; Verola, O; Rivet, J; Tesniere, A; Dubertret, L; Basset-Seguin, N

1999-09-23

The p16 gene expresses two alternative transcripts (p16alpha and p16beta) involved in tumor suppression via the retinoblastoma (Rb) or p53 pathways. Disruption of these pathways can occur through inactivation of p16 or p53, or activating mutations of cyclin dependant kinase 4 gene (Cdk4). We searched for p16, Cdk4 and p53 gene mutations in 20 squamous cell carcinomas (SSCs), 1 actinic keratosis (AK), and 28 basal cell carcinomas (BCCs), using PCR-SSCP. A deletion and methylation analysis of p16 was also performed. Six different mutations (12%) were detected in exon 2 of p16 (common to p16alpha and p16beta), in five out of 21 squamous lesions (24%) (one AK and four SCCs) and one out of 28 BCCs (3.5%). These included four (66%) ultraviolet (UV)-type mutations (two tandems CC : GG to TT : AA transitions and two C : G to T : A transitions at dipyrimidic site) and two transversions. P53 mutations were present in 18 samples (37%), mostly of UV type. Of these, only two (one BCC and one AK) harboured simultaneously mutations of p16, but with no consequence on p16beta transcript. Our data demonstrate for the first time the presence of p16 UV induced mutations in non melanoma skin cancer, particularly in the most aggressive SCC type, and support that p16 and p53 are involved in two independent pathways in skin carcinogenesis.

75 FR 50799 - Qualification of Drivers; Exemption Applications; Vision

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-17

... posts all comments received without change to http://www.regulations.gov , including any personal... each applicant continues to meet the vision exemption standards. These factors provide an adequate... Policy and Program Development. [FR Doc. 2010-20226 Filed 8-16-10; 8:45 am] BILLING CODE 4910-EX-P ...

p16INK4A expression as biomarker for HPV 16-related vulvar neoplasias.

PubMed

Riethdorf, Sabine; Neffen, Eduardo F; Cviko, Aida; Löning, Thomas; Crum, Christopher P; Riethdorf, Lutz

2004-12-01

Up-regulation of p16INK4A is associated with high-risk human papillomavirus (HPV) in preinvasive and invasive cervical neoplasia. However, its expression in vulvar carcinomas, which have a diverse pathogenesis, has not been extensively studied. One hundred seventy-seven vulvar intraepithelial neoplasms (VIN), squamous cell carcinomas (SCC), and benign squamous epithelia were analyzed for p16 expression. RNA/RNA in situ hybridization was used to detect HPV 16 E6/E7 transcripts in 112. Ninety-five percent of VIN 3 and basaloid or warty SCCs (76/80) and 4% of keratinizing SCC (2/48) were moderately to strongly immunopositive for p16, which localized to nucleus and cytoplasm; 52/58 analyzed (90%) contained HPV 16 transcripts. The positive predictive value (PPV) of moderate to strong diffuse p16 immunostaining and HPV positivity for the diagnosis of VIN 3 and of basaloid or warty SCC was 97% and 95%, respectively. Conversely, 94% of keratinizing SCC contained heterogeneous staining, and when present, it was strictly cytoplasmic and frequently localized to the cells at the epithelial-stromal interface. Benign squamous epithelia were p16 negative, with the exception of lichen sclerosus, which contained focal and heterogeneously p16 positive in 42%. As in the cervix, intense diffuse p16 expression supports an HPV-related neoplastic process in vulvar neoplasia, irrespective of the level of differentiation. Up-regulation of p16 at the epithelial-stromal interface in HPV negative keratinizing SCCs is consistent with an HPV-independent response to alterations associated with invasion. These disparate patterns of p16 expression underscore 2 different mechanisms for p16 expression in HPV-related and HPV-unrelated vulvar carcinomas.

16 CFR 1210.16 - Production testing.

Code of Federal Regulations, 2010 CFR

2010-01-01

... in the manufacturing process, the assembly process, the equipment used to manufacture the product, or... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Production testing. 1210.16 Section 1210.16... STANDARD FOR CIGARETTE LIGHTERS Certification Requirements § 1210.16 Production testing. (a) General...

Personal Living Skills 10-20-30. Home Economics Curriculum.

ERIC Educational Resources Information Center

Alberta Dept. of Education, Edmonton.

This home economics curriculum contains 16 modules for teaching personal, family, and applied skills in high schools in Alberta. The modules may be used in courses on various levels. Each module consists of generalizations, objectives, suggested learning experiences related to resources, and a content checklist. Modules in the personal living…

16 CFR 315.10 - Severability.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Severability. 315.10 Section 315.10 Commercial Practices FEDERAL TRADE COMMISSION REGULATIONS UNDER SPECIFIC ACTS OF CONGRESS CONTACT LENS RULE § 315.10 Severability. The provisions of this part are separate and severable from one another. If any...

16 CFR 2.10 - Depositions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Depositions. 2.10 Section 2.10 Commercial... Inquiries; Investigations; Compulsory Processes § 2.10 Depositions. In investigations other than those... taken by deposition at any stage of such investigation. Such depositions may be taken before any person...

16 CFR 2.10 - Depositions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 16 Commercial Practices 1 2011-01-01 2011-01-01 false Depositions. 2.10 Section 2.10 Commercial... Inquiries; Investigations; Compulsory Processes § 2.10 Depositions. In investigations other than those... taken by deposition at any stage of such investigation. Such depositions may be taken before any person...

Manufactured Housing--The Modular Home in Texas.

ERIC Educational Resources Information Center

Sindt, Roger P.

This report deals principally with modular homes (permanently sited structures) although it also presents some recent information on mobile homes. In 1976, modular home construction companies were surveyed in Texas and across the United States to assess the extent of their construction activity and market penetration and to gather some insight…

Clinical Effectiveness of Integrating Depression Care Management into Medicare Home Health: The Depression CAREPATH Cluster-Randomized Trial

PubMed Central

Bruce, Martha L.; Raue, Patrick J.; Reilly, Catherine F.; Greenberg, Rebecca L.; Meyers, Barnett S.; Banerjee, Samprit; Pickett, Yolonda R.; Sheeran, Thomas F.; Ghesquiere, Angela; Zukowski, Diane; Rosas, Vianca H.; McLaughlin, Jeanne; Pledger, Lori; Doyle, Joan; Joachim, Pamela; Leon, Andrew C.

2015-01-01

Importance Depression is highly prevalent, inadequately treated, and contributes to hospitalization and other poor outcomes in older home healthcare patients. Feasible and effective interventions are needed to reduce this burden of depression. Objective To determine whether among older Medicare home health recipients who screen positive for depression, patients of nurses randomized to intervention have greater improvement in depressive symptoms over one year compared to patients receiving enhanced usual care. Design The cluster-randomized effectiveness trial randomized nurse-teams to Intervention (12 teams) or enhanced usual care (9 teams). Patients were recruited 2009–2012, assessed, and followed at 3, 6, and 12-months by research staff blind to intervention status. Setting Conducted at six home healthcare agencies nationwide. Patients interviewed at home and by telephone. Participants Medicare home health patients age ≥65 who screened positive for depression on routine nurse assessments. Of 502 eligible patients, 306 enrolled. Intervention Depression CAREPATH (CARE for PATients at Home) requires nurses to manage depression during routine home visits by weekly symptom assessment, medication management, care coordination, education, goal setting. Training totaled 7 hours (4 on-site, 3 web). Researchers telephoned supervisors every other week. Main Outcome and Measure Depression severity, assessed by 24-item Hamilton Depression Rating Scale (HDRS). Results 306 participants were predominately female (69.6%), diverse (18.0% Black, 16.0% Hispanic), average age 76.5 (SD=8.0) years. In full sample, the intervention had no effect (treatment × time interaction: P=0.13). Adjusted HDRS scores (CAREPATH vs control) did not differ at three (10.5 vs 11.4; P=0.26) or six months (9.3 vs 10.5; P=0.12), barely reaching significance at twelve months (8.7 vs 10.6; P=0.05). In subsample with mild depression (HDRS<10), the intervention had no effect (P=.90) and HDRS did not differ

10 CFR 1046.16 - Training certification.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Training certification. 1046.16 Section 1046.16 Energy... Personnel § 1046.16 Training certification. DOE contractors shall employ as protective force personnel only individuals who have successfully completed all applicable training and qualification standards set forth in...

10 CFR 1046.16 - Training certification.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Training certification. 1046.16 Section 1046.16 Energy... Personnel § 1046.16 Training certification. DOE contractors shall employ as protective force personnel only individuals who have successfully completed all applicable training and qualification standards set forth in...

16 CFR 1014.10 - Fees.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Fees. 1014.10 Section 1014.10 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION GENERAL POLICIES AND PROCEDURES IMPLEMENTING THE PRIVACY ACT OF 1974 § 1014.10 Fees. The Commission shall not charge an individual for the costs of making a search for...

75 FR 5888 - Federal Manufactured Home Construction and Safety Standards and Other Orders: HUD Statements That...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-05

... DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT 24 CFR Parts 3280 and 3282 [Docket No. FR-5343-IN-01... Housing Programs, Department of Housing and Urban Development, 451 Seventh Street, SW., Room 9164... provided that the consensus committee was to develop the original proposed model installation standards for...

26 CFR 31.3121(a)(10)-1 - Payments to certain home workers.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 26 Internal Revenue 15 2013-04-01 2013-04-01 false Payments to certain home workers. 31.3121(a)(10... Provisions § 31.3121(a)(10)-1 Payments to certain home workers. (a) The term wages does not include remuneration paid by an employer in any calendar year to an employee for service performed as a home worker who...

26 CFR 31.3121(a)(10)-1 - Payments to certain home workers.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 26 Internal Revenue 15 2010-04-01 2010-04-01 false Payments to certain home workers. 31.3121(a)(10... Provisions § 31.3121(a)(10)-1 Payments to certain home workers. (a) The term wages does not include remuneration paid by an employer in any calendar year to an employee for service performed as a home worker who...

26 CFR 31.3121(a)(10)-1 - Payments to certain home workers.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 26 Internal Revenue 15 2012-04-01 2012-04-01 false Payments to certain home workers. 31.3121(a)(10... Provisions § 31.3121(a)(10)-1 Payments to certain home workers. (a) The term wages does not include remuneration paid by an employer in any calendar year to an employee for service performed as a home worker who...

26 CFR 31.3121(a)(10)-1 - Payments to certain home workers.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 26 Internal Revenue 15 2014-04-01 2014-04-01 false Payments to certain home workers. 31.3121(a)(10... Provisions § 31.3121(a)(10)-1 Payments to certain home workers. (a) The term wages does not include remuneration paid by an employer in any calendar year to an employee for service performed as a home worker who...

26 CFR 31.3121(a)(10)-1 - Payments to certain home workers.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 26 Internal Revenue 15 2011-04-01 2011-04-01 false Payments to certain home workers. 31.3121(a)(10... Provisions § 31.3121(a)(10)-1 Payments to certain home workers. (a) The term wages does not include remuneration paid by an employer in any calendar year to an employee for service performed as a home worker who...

10 CFR 602.16 - National security.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false National security. 602.16 Section 602.16 Energy DEPARTMENT... ASSISTANCE PROGRAM § 602.16 National security. Activities under the Epidemiology and Other Health Studies..., Formerly Restricted Data, National Security Information). However, if in the opinion of the recipient or...

10 CFR 602.16 - National security.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 4 2013-01-01 2013-01-01 false National security. 602.16 Section 602.16 Energy DEPARTMENT... ASSISTANCE PROGRAM § 602.16 National security. Activities under the Epidemiology and Other Health Studies..., Formerly Restricted Data, National Security Information). However, if in the opinion of the recipient or...

10 CFR 602.16 - National security.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 4 2014-01-01 2014-01-01 false National security. 602.16 Section 602.16 Energy DEPARTMENT... ASSISTANCE PROGRAM § 602.16 National security. Activities under the Epidemiology and Other Health Studies..., Formerly Restricted Data, National Security Information). However, if in the opinion of the recipient or...

10 CFR 32.16 - Certain items containing byproduct material: Records and reports of transfer.

Code of Federal Regulations, 2010 CFR

2010-01-01

... reports of transfer. 32.16 Section 32.16 Energy NUCLEAR REGULATORY COMMISSION SPECIFIC DOMESTIC LICENSES TO MANUFACTURE OR TRANSFER CERTAIN ITEMS CONTAINING BYPRODUCT MATERIAL Exempt Concentrations and Items § 32.16 Certain items containing byproduct material: Records and reports of transfer. (a) Each...

10 CFR 32.16 - Certain items containing byproduct material: Records and reports of transfer.

Code of Federal Regulations, 2011 CFR

2011-01-01

... reports of transfer. 32.16 Section 32.16 Energy NUCLEAR REGULATORY COMMISSION SPECIFIC DOMESTIC LICENSES TO MANUFACTURE OR TRANSFER CERTAIN ITEMS CONTAINING BYPRODUCT MATERIAL Exempt Concentrations and Items § 32.16 Certain items containing byproduct material: Records and reports of transfer. (a) Each...

[Norovirus outbreaks in hospitals and nursing homes in Catalonia, Spain].

PubMed

Godoy, Pere; Domínguez, Angela; Alvarez, Josep; Camps, Neus; Barrabeig, Irene; Bartolomé, Rosa; Sala, María Rosa; Ferre, Dolors; Pañella, Helena; Torres, Joan; Minguell, Sofía; Alsedà, Miquel; Pumares, Analía

2009-01-01

The low infectious dose and multiple transmission routes favour the appearance of norovirus outbreaks. The objective of this study was to compare the incidence of norovirus outbreaks in hospitals and nursing homes in Catalonia. A descriptive study of norovirus outbreaks between 15/10/2004 and 30/10/2005 was carried out. An epidemiological survey was completed for each outbreak. Norovirus in clinical samples was determined by PCR techniques. The incidence in each centre and the annual incidence of outbreaks by centre were calculated. Differences were calculated using the chi-square test and the Student's t test, taking a p value of > 0.05 as significant. Seventeen outbreaks (6 in hospitals and 11 in nursing homes) were detected. The global attack rate was 33.4% (652/1951) and was slightly higher in nursing homes (35.2%) than in hospitals (31.4%). A total of 94.1% (16/17) of outbreaks were caused by person-to-person transmission and only 5.9% (1/17) by foods. The mean number of days between the first and last case was 11.4 (SD = 6.9). The mean duration of symptoms was 2.39 days (SD=1.6), and was higher hospitals, 2.63 (SD=1.7), than in nursing homes, 1.97 (SD=1.7) (p < 0.0001). Norovirus is responsible for a large number of outbreaks due to person-to-person transmission. Control should be standardized to reduce the number and duration of outbreaks.

40 CFR 417.10 - Applicability; description of the soap manufacturing by batch kettle subcategory.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 28 2010-07-01 2010-07-01 true Applicability; description of the soap manufacturing by batch kettle subcategory. 417.10 Section 417.10 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS SOAP AND DETERGENT MANUFACTURING POINT SOURCE CATEGORY Soap Manufacturing by...

40 CFR 417.10 - Applicability; description of the soap manufacturing by batch kettle subcategory.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 29 2011-07-01 2009-07-01 true Applicability; description of the soap manufacturing by batch kettle subcategory. 417.10 Section 417.10 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS SOAP AND DETERGENT MANUFACTURING POINT SOURCE CATEGORY Soap Manufacturing by...

Inhibitory Effect of Dried Pomegranate Concentration Powder on Melanogenesis in B16F10 Melanoma Cells; Involvement of p38 and PKA Signaling Pathways

PubMed Central

Kang, Su Jin; Choi, Beom Rak; Lee, Eun Kyoung; Kim, Seung Hee; Yi, Hae Yeon; Park, Hye Rim; Song, Chang Hyun; Lee, Young Joon; Ku, Sae Kwang

2015-01-01

Plants rich in antioxidant substances may be useful for preventing skin aging. Pomegranates, containing flavonoids and other polyphenolic compounds, are widely consumed due to their beneficial properties. We examined the underlying mechanisms of dried pomegranate concentrate powder (PCP) on melanin synthesis in B16F10 melanoma cells. The antioxidant effects of PCP were determined by measuring free radical scavenging capacity and transcript levels of antioxidant enzymes. To explore the inhibitory effects of PCP on melanin synthesis, we measured tyrosinase activity and melanin content in α-melanocyte stimulating hormone (α-MSH)-stimulated B16F10 cells. In addition, the levels of tyrosinase-related protein-1 (TRP-1), TRP-2, tyrosinase, and microphthalmia-associated transcription factor (MITF) expression were determined by Western blotting. Changes in the phosphorylation status of protein kinase A (PKA), cAMP response element-binding protein (CREB), mitogen-activated protein kinases (MAPKs), phosphatidylinositol 3-kinase (PI3K), serine/threonine kinase Akt, and glycogen kinase 3β (GSK3β) were also examined. The free radical scavenging activity of PCP increased in a dose-dependent manner. In PCP-treated B16F10 cells, transcript levels of glutathione peroxidase-1 (GPx-1) were increased compared with α-MSH-stimulated cells. In addition, PCP led to the down-regulation of phospho-p38, phospho-PKA, phospho-CREB, phospho-GSK3β, MITF, and TRP-1 compared with α-MSH-stimulated B16F10 cells. We believe this effect may be associated with PCP activity, which leads to the inhibition of melanin production and tyrosinase activity. These results suggest that PCP decreases tyrosinase activity and melanin production via inactivation of the p38 and PKA signaling pathways, and subsequently decreases phosphorylation of CREB, MITF, and melanogenic enzymes. These observations provided new insights on the molecular mechanisms of the skin-whitening property of PCP. PMID:26473849

Home Manufacture of Drugs: An Online Investigation and a Toxicological Reality Check of Online Discussions on Drug Chemistry.

PubMed

Hearne, Evelyn; Alves, Emanuele Amorim; Van Hout, Marie Claire; Grund, Jean-Paul C

2017-01-01

Emerging trends in market dynamics and the use of new psychoactive substances are both a public health concern and a complex regulatory issue. One novel area of investigation is the availability of homemade opioids, amphetamines and dissociatives, and the potential fueling of interest in clandestine home manufacture of drugs via the Internet. We illustrate here how online communal folk pharmacology of homemade drugs on drug website forums may actually inform home manufacture practices or contribute to the reduction of harms associated with this practice. Discrepancies between online information around purification and making homemade drugs safer, and the synthesis of the same substances in a proper laboratory environment, exist. Moderation and shutdown of synthesis queries and discussions online are grounded in drug websites adhering to harm-reduction principles by facilitating discussions around purification of homemade drugs only. Drug discussion forums should consider reevaluating their policies on chemistry discussions in aiming to reach people who cannot or will not refrain from cooking their own drugs with credible information that may contribute to reductions in the harms associated with this practice.

75 FR 10216 - The Manufacturing Council: Meeting of the Manufacturing Council

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-05

...: March 22, 2010. Time: 1:30-3 p.m. (ET). ADDRESSES: Department of Commerce, 1401 Constitution Avenue, NW... Manufacturing Council, Room 4043, 1401 Constitution Avenue, NW., Washington, DC, 20230, telephone 202-482-4501..., Room 4043, 1401 Constitution Avenue, NW., Washington, DC, 20230, telephone: 202-482-4501, e-mail: Marc...

28 CFR 16.10 - Preservation of records.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Preservation of records. 16.10 Section 16.10 Judicial Administration DEPARTMENT OF JUSTICE PRODUCTION OR DISCLOSURE OF MATERIAL OR INFORMATION... title 44 of the United States Code or the National Archives and Records Administration's General Records...

10 CFR 51.16 - Proprietary information.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Proprietary information. 51.16 Section 51.16 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) ENVIRONMENTAL PROTECTION REGULATIONS FOR DOMESTIC LICENSING AND RELATED REGULATORY FUNCTIONS National Environmental Policy Act-Regulations Implementing Section 102(2...

10 CFR 51.16 - Proprietary information.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 2 2013-01-01 2013-01-01 false Proprietary information. 51.16 Section 51.16 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) ENVIRONMENTAL PROTECTION REGULATIONS FOR DOMESTIC LICENSING AND RELATED REGULATORY FUNCTIONS National Environmental Policy Act-Regulations Implementing Section 102(2...

78 FR 4157 - Notice of Proposed Information Collection for Public Comment: Survey of Manufactured (Mobile...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-18

... mandated indexing of loan limits. Section 2145 (b) of the Housing and Economic Recovery Act (HERA) of 2008 requires HUD to develop a method of indexing to annually adjust Title I manufactured home loan limits. This...

Characterisation of a thiamine diphosphate-dependent alpha-keto acid decarboxylase from Proteus mirabilis JN458.

PubMed

Wang, Biying; Bai, Yajun; Fan, Taiping; Zheng, Xiaohui; Cai, Yujie

2017-10-01

Alpha-keto acid decarboxylases can convert keto acids to their corresponding aldehydes, which are often volatile aroma compounds. The gene encoding α-keto acid decarboxylase in Proteus mirabilis JN458 was cloned, and the enzyme overexpressed in Escherichia coli BL21 (DE3), purified in high yield, and characterised. The molecular weight is 62.291kDa by MALDI-TOF MS, and optimum activity at pH 6.0 and 40-50°C. The enzyme is a typical decarboxylase, dependent on thiamine diphosphate and Mg 2+ as cofactors. For the decarboxylation reaction, the enzyme displayed a broad substrate range. Kinetic parameters were determined using 4-methyl-2-oxopentanoic acid, phenyl pyruvate and 3-methyl-2-oxopentanoic acid as substrates. K m and k cat values for phenyl pyruvate were 0.62mM and 77.38s -1 , respectively, and the k cat /K m value was 124.81mM -1 s -1 . The enzyme properties suggest it may act effectively under cheese ripening conditions. Copyright © 2017. Published by Elsevier Ltd.

Intelligent Home Control System Based on ARM10

NASA Astrophysics Data System (ADS)

Chen, G. X.; Jiang, J.; Zhong, L. H.

2017-10-01

Intelligent home is becoming the hot spot of social attention in the 21st century. When it is in China, it is a really new industry. However, there is no doubt that Intelligent home will become a new economic growth point of social development; it will change the life-style of human being. To develop the intelligent home, we should keep up with the development trend of technology. This is the reason why I talk about the intelligent home control system here. In this paper, intelligent home control system is designed for alarm and remote control on gas- leaking, fire disaster, earthquake prediction, etc., by examining environmental changes around house. When the Intelligent home control system has detected an accident occurs, the processor will communicate with the GSM module, informing the house keeper the occurrence of accident. User can receive and send the message to the system to cut the power by mobile phone. The system can get access to DCCthrough ARM10 JTAG interface, using DCC to send and receive messages. At the same time, the debugger on the host is mainly used to receive the user’s command and send it to the debug component in the target system. The data that returned from the target system is received and displayed to the user in a certain format.

41 CFR 302-10.5 - May I transport a mobile home over water?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 4 2010-07-01 2010-07-01 false May I transport a mobile home over water? 302-10.5 Section 302-10.5 Public Contracts and Property Management Federal Travel... transport a mobile home over water? Yes, you may transport a mobile home over water when both the points of...

41 CFR 302-10.5 - May I transport a mobile home over water?

Code of Federal Regulations, 2011 CFR

2011-07-01

... 41 Public Contracts and Property Management 4 2011-07-01 2011-07-01 false May I transport a mobile home over water? 302-10.5 Section 302-10.5 Public Contracts and Property Management Federal Travel... transport a mobile home over water? Yes, you may transport a mobile home over water when both the points of...

Wolf-Hirschhorn (4p-) syndrome: prenatal diagnosis, molecular cytogenetic characterization and association with a 1.2-Mb microduplication at 8p22-p21.3 and a 1.1-Mb microduplication at 10p15.3 in a fetus with an apparently pure 4p deletion.

PubMed

Chen, Chih-Ping; Su, Yi-Ning; Chen, Yi-Yung; Su, Jun-Wei; Chern, Schu-Rern; Chen, Yu-Ting; Chen, Wen-Lin; Chen, Li-Feng; Wang, Wayseen

2011-12-01

To present prenatal diagnosis and molecular cytogenetic characterization of Wolf-Hirschhorn syndrome (WHS) associated with microduplications at 8p and 10p in a fetus with an apparently pure 4p deletion. A 35-year-old gravida 2, para 1 woman underwent amniocentesis at 18 weeks of gestation because of advanced maternal age. Her husband was 38 years of age. There was no family history of congenital malformations. Amniocentesis revealed a karyotype of 46,XY,del(4p16.1). The parental karyotypes were normal. Array comparative genomic hybridization (aCGH) analysis revealed a 6.5-Mb deletion at 4p16.3-p16.1, a 1.2-Mb microduplication at 8p22-p21.3, and a 1.1-Mb microduplication at 10p15.3, or arr cgh 4p16.3p16.1 (0-6,531,998 bp)×1, 8p22p21.3 (18,705,388-19,940,445 bp)×3, 10p15.3 (0-1,105,065 bp)×3. Polymorphic DNA marker analysis confirmed a paternal origin of 4p deletion. Prenatal ultrasound revealed facial dysmorphism and hypospadias. The aCGH analysis of the parents revealed no genomic imbalance. Fluorescence in situ hybridization study showed an unbalanced reciprocal translocation between chromosomes 4 and 10 at bands 4p16.1 and 10p15.3. The cytogenetic result, thus, was 46,XY,der(4)t(4;10)(p16.1;p15.3),dup(8)(p21.3p22). The parents elected to terminate the pregnancy, and a 470-g malformed fetus was delivered. The present case provides evidence that an apparently pure 4p deletion can be associated with subtle chromosome imbalances in other chromosomes. Copyright © 2011. Published by Elsevier B.V.

Expression of p16(INK4A) gene in human pituitary tumours.

PubMed

Machiavelli, Gloria; Cotignola, Javier; Danilowicz, Karina; Carbonara, Carolina; Paes de Lima, Andrea; Basso, Armando; Bruno, Oscar Domingo; Szijan, Irene

2008-01-01

Pituitary adenomas comprise 10-15% of primary intracranial tumours but the mechanisms leading to tumour development are yet to be clearly established. The retinoblastoma pathway, which regulates the progression through the cell cycle, is often deregulated in different types of tumours. We studied the cyclin-dependent kinase inhibitor p16(INK4A) gene expression at mRNA level in human pituitary adenomas. Forty-six tumour specimens of different subtypes, 21 clinically non-functioning, 12 growth hormone-secreting, 6 prolactin-secreting, 6 adrenocorticotropin-secreting, and 1 thyrotropin-secreting tumours were studied. All clinically non-functioning and most of the hormone-secreting tumours were macroadenomas (38/46). The RT-PCR assay and electrophoresis of the PCR-products showed that p16(INK4A) mRNA was undetectable in: 62% of non-functioning, 8% of growth hormone-secreting, 17% of prolactin-secreting and 17% of adrenocorticotropin-secreting adenomas. Forty percent of all macroadenomas and 25% of microadenomas had negative p16(INK4A) mRNA, the latter results suggest that the absence of p16(INK4A) product might be an early event in tumours with no expression of this suppressor gene. Within the non-functioning adenomas 63% were "null cell" and 37% were positive for some hormone, both subgroups showed similar percentage of cases with absence of p16(INK4A) mRNA. Our results show that clinically non-functioning macroadenomas have impaired p16(INK4A) expression in a clearly higher proportion than any other pituitary tumour subtype investigated. Other regulatory pathways may be implicated in the development of tumours with positive p16(INK4A) expression.

77 FR 11186 - In the Matter of the Review of the Designation of the Islamic Jihad Union; AKA Islamic Jihad...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-24

... maintained. This determination shall be published in the Federal Register. Dated: February 16, 2012. Hillary Rodham Clinton, Secretary of State. [FR Doc. 2012-4334 Filed 2-23-12; 8:45 am] BILLING CODE 4710-10-P ...

[Pharmacotherapy in nursing homes].

PubMed

Kersten, Hege; Ruths, Sabine; Wyller, Torgeir Bruun

2009-09-10

There is a high risk of drug-related problems in nursing homes due to polypharmacy, multi-morbidity and age-related changes. We describe the drug use and compare the pharmacotherapy in two nursing homes with different staffing of physicians. We included 48 long-term patients from two nursing homes in Oslo; i.e. nursing home A (24 patients) and nursing home B (24 patients). A pharmacist recorded information on patients' drug use, identified and classified drug-related problems, and classified the drugs used according to their anticholinergic burden. Two physicians (with experience in geriatrics and nursing home medicine) assessed the clinical importance of the drug-related problems independently from each other. The physicians were blinded with respect to which nursing home the patients came from. Patients in nursing home A used a median (interquartile range [IQR]) of 7.0 (5.3-11.0) drugs, and those in nursing home B used 9.5 (8.0-12.8); the median difference was 2.0, 95% CI 1.0-4.0, p = 0.006). Patients also had lower anticholinergic drug scores in nursing home A (1.0 [0.0-2.0]) than in nursing home B (2.0 [2.0-3.8]); median difference 1.0, 95% CI 0.0-2.0, p = 0.009). Patients in home A also had lower numbers of drug-related problems (3.0 [2.0-4.0]) than those in home B (5.5 [3.3-8.0]); median difference 1.0, 85% CI 0.0-3.0, p = 0.007. No significant differences were found between the nursing homes with regard to patients' age, co-morbidity, kidney function, or dementia state, but nursing home A had a better staffing of physicians. The number of drugs used as well as the quality indicators varied considerably between the nursing homes assessed. Differences in physician staffing might be one reasonable explanation. Our study highlights the importance of systematic multidisciplinary medication reviews for quality improvement in nursing homes.

[Location of semen collection and semen quality: clinic-collected versus home-collected samples].

PubMed

Wang, Wei; Zhong, Zhi-min; Su, Ning; Peng, Ya-ya; Huang, Ting-ting

2014-11-01

To investigate the differences in semen quality between samples collected by masturbation in the clinic and at home. Based on the WHO guidelines, we analyzed the ejaculates collected by masturbation in the clinic and at home from 342 men under infertility assessment and measured the contents of such biochemical markers in the seminal plasma as neutral α-glucosidase, zinc, and fructose. According to the location of semen collection, we divided the samples into two groups, clinic-collected and home-collected, and analyzed the differences in the semen parameters between the two groups with the SPSS 16.0 software. Compared with the clinic-collected semen, the home-collected samples had significantly higher mean values in semen volume (4.0 vs 4.9%), sperm concentration (41 vs 64 x 10(6)/ml), total sperm count (175 vs 270 x 10(6) per ejaculate), progressive sperm motility (40 vs 52%), total count of progressively motile sperm (82 vs 135 x 10(6) per ejaculate) (all P <0.05). No significant differences were found between the two groups in normal sperm morphology (4.0 vs 5.0%) and the contents of neutral α-glucosidase (26 vs 24 mU per ejaculate), zinc (8.0 vs 8.0 μmol per ejaculate), and fructose (62 vs 60 μmol per ejaculate) (all P >0.05). Abnormal sperm concentration (<20 x 10(6)/ml) was observed in significantly fewer of the home-collected samples than the clinic-collected ones (18% [62/342] vs 30% [103/342], P<0.05), and so was abnormal progressive sperm motility (<32%) (64% [219/342] vs 75% [256/342], P<0.05). Our findings show that semen samples collected by masturbation at home has a higher quality than those collected in the clinic. So the location of semen collection should be taken into consideration in infertility investigation.

Salivary flow rate and pH in patients with oral pathologies.

PubMed

Foglio-Bonda, P L; Brilli, K; Pattarino, F; Foglio-Bonda, A

2017-01-01

Determine salivary pH and flow rate (FR) in a sample of 164 patients who came to Oral Pathology ambulatory, 84 suffering from oral lesions and 80 without oral lesions. Another aim was to evaluate factors that influence salivary flow rate. Subjects underwent clinical examination and completed an anamnestic questionnaire in order to obtain useful information that was used to classify participants in different groups. Unstimulated whole saliva (UWS) was collected using the spitting method at 11:00 am. The FR was evaluated with the weighing technique and a portable pHmeter, equipped with a microelectrode, was used to measure pH. Both univariate and classification (single and Random Forest) analyses were performed. The data analysis showed that FR and pH showed significant differences (p < 0.001) between patients with oral lesions (FR = 0.336 mL/min, pH = 6.69) and the ones without oral lesions (FR = 0.492 mL/min, pH = 6.96). By Random Forest, oral lesions and antihypertensive drugs were ranked in the top two among the evaluated variables to discretize subjects with FR = 0.16 mL/min. Our study shows that there is a relationship between oral lesions, antihypertensive drugs and alteration of pH and FR.

16 CFR 503.3 - Name and place of business of manufacturer, packer, or distributor.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 16 Commercial Practices 1 2012-01-01 2012-01-01 false Name and place of business of manufacturer... LABELING ACT STATEMENTS OF GENERAL POLICY OR INTERPRETATION § 503.3 Name and place of business of... by the addition of any substance which changes the identity of the bulk, ceases to be the...

16 CFR 503.3 - Name and place of business of manufacturer, packer, or distributor.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 16 Commercial Practices 1 2011-01-01 2011-01-01 false Name and place of business of manufacturer... LABELING ACT STATEMENTS OF GENERAL POLICY OR INTERPRETATION § 503.3 Name and place of business of... by the addition of any substance which changes the identity of the bulk, ceases to be the...

16 CFR 503.3 - Name and place of business of manufacturer, packer, or distributor.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 16 Commercial Practices 1 2014-01-01 2014-01-01 false Name and place of business of manufacturer... LABELING ACT STATEMENTS OF GENERAL POLICY OR INTERPRETATION § 503.3 Name and place of business of... by the addition of any substance which changes the identity of the bulk, ceases to be the...

16 CFR 503.3 - Name and place of business of manufacturer, packer, or distributor.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 16 Commercial Practices 1 2013-01-01 2013-01-01 false Name and place of business of manufacturer... LABELING ACT STATEMENTS OF GENERAL POLICY OR INTERPRETATION § 503.3 Name and place of business of... by the addition of any substance which changes the identity of the bulk, ceases to be the...

10 CFR Appendix G to Subpart B of... - Uniform Test Method for Measuring the Energy Consumption of Unvented Home Heating Equipment

Code of Federal Regulations, 2013 CFR

2013-01-01

... of Unvented Home Heating Equipment G Appendix G to Subpart B of Part 430 Energy DEPARTMENT OF ENERGY..., App. G Appendix G to Subpart B of Part 430—Uniform Test Method for Measuring the Energy Consumption of.... 28, 1984] Effective Date Note: At 77 FR 74571, Dec. 17, 2012, appendix G to subpart B of part 430 was...

Design, Manufacture, and Experimental Serviceability Validation of ITER Blanket Components

NASA Astrophysics Data System (ADS)

Leshukov, A. Yu.; Strebkov, Yu. S.; Sviridenko, M. N.; Safronov, V. M.; Putrik, A. B.

2017-12-01

In 2014, the Russian Federation and the ITER International Organization signed two Procurement Arrangements (PAs) for ITER blanket components: 1.6.P1ARF.01 "Blanket First Wall" of February 14, 2014, and 1.6.P3.RF.01 "Blanket Module Connections" of December 19, 2014. The first PA stipulates development, manufacture, testing, and delivery to the ITER site of 179 Enhanced Heat Flux (EHF) First Wall (FW) Panels intended for withstanding the heat flux from the plasma up to 4.7MW/m2. Two Russian institutions, NIIEFA (Efremov Institute) and NIKIET, are responsible for the implementation of this PA. NIIEFA manufactures plasma-facing components (PFCs) of the EHF FW panels and performs the final assembly and testing of the panels, and NIKIET manufactures FW beam structures, load-bearing structures of PFCs, and all elements of the panel attachment system. As for the second PA, NIKIET is the sole official supplier of flexible blanket supports, electrical insulation key pads (EIKPs), and blanket module/vacuum vessel electrical connectors. Joint activities of NIKIET and NIIEFA for implementing PA 1.6.P1ARF.01 are briefly described, and information on implementation of PA 1.6.P3.RF.01 is given. Results of the engineering design and research efforts in the scope of the above PAs in 2015-2016 are reported, and results of developing the technology for manufacturing ITER blanket components are presented.

16 CFR 1051.10 - Granting petitions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Granting petitions. 1051.10 Section 1051.10... § 1051.10 Granting petitions. (a) The Commission shall either grant or deny a petition within a reasonable time after it is filed, taking into account the resources available for processing the petition...

38 CFR 58.13 - VA Form 10-10SH-State Home Program Application for Veteran Care Medical Certification.