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  1. The Reality of Neandertal Symbolic Behavior at the Grotte du Renne, Arcy-sur-Cure, France

    PubMed Central

    Caron, François; d'Errico, Francesco; Del Moral, Pierre; Santos, Frédéric; Zilhão, João

    2011-01-01

    Background The question of whether symbolically mediated behavior is exclusive to modern humans or shared with anatomically archaic populations such as the Neandertals is hotly debated. At the Grotte du Renne, Arcy-sur-Cure, France, the Châtelperronian levels contain Neandertal remains and large numbers of personal ornaments, decorated bone tools and colorants, but it has been suggested that this association reflects intrusion of the symbolic artifacts from the overlying Protoaurignacian and/or of the Neandertal remains from the underlying Mousterian. Methodology/Principal Findings We tested these hypotheses against the horizontal and vertical distributions of the various categories of diagnostic finds and statistically assessed the probability that the Châtelperronian levels are of mixed composition. Our results reject that the associations result from large or small scale, localized or generalized post-depositional displacement, and they imply that incomplete sample decontamination is the parsimonious explanation for the stratigraphic anomalies seen in the radiocarbon dating of the sequence. Conclusions/Significance The symbolic artifacts in the Châtelperronian of the Grotte du Renne are indeed Neandertal material culture. PMID:21738702

  2. From Bretonneau to therapeutic antibodies, from specificity to specific remedies, Saint-Cyr-Sur-Loire, France, November 19, 2012

    PubMed Central

    Marchand, Claire; Nouat, Romaric; Watier, Hervé

    2013-01-01

    Held on November 19, 2012 in Saint-Cyr-sur-Loire, France, the symposium “From Bretonneau to therapeutic antibodies, from specificity to specific remedies” focused on the historical development of antibodies as therapeutics, with an emphasis on the seminal work of the French physician Pierre-Fidèle Bretonneau (1778–1862). The morning session was devoted to discussion of the evolution of the concept of specificity in medicine, which started with an epistemological definition. The contributions of Bretonneau to the emergence of the concept of specificity, notably with his studies on diphtheria, and the subsequent development of antidiphtheric serotherapy in Europe during the period 1894–1898 were then presented in detail. The afternoon session began with a presentation on the role of French physiologists during the years 1860–1890 in establishing the basic concepts of specific immunity and the principles of serotherapy. The history of antivenom serotherapy, particularly its discovery by Césaire Phisalix, and the development of antilymphocyte globulins as successful transplantation drugs were then discussed. The symposium ended with the inauguration of a stele representing Bretonneau, who lived in Saint-Cyr-sur-Loire and died 150 y ago. PMID:23924799

  3. France

    NASA Technical Reports Server (NTRS)

    2002-01-01

    Every July, the world's best cyclists race more than 3500 km around France, and sometimes the surrounding countries, in the Tour de France. This image from the Moderate resolution Imaging Spectroradiometer (MODIS) shows the varied terrain which challenges the riders. The race started in western France at Futuroscope, and headed toward Brittany. In these mostly flat 'stages' (as each day's race is called) sprinting specialists usually dash for the finish out of the main pack of riders. The race then moved to the Pyrenees mountains, in southern France along the border with Spain. Climbers and the overall favorites shine in the mountains, often gaining 10 minutes or more on their rivals. Only a few days after the Pyrenees climbs the race was again in the mountains. First Mont Ventoux, an extinct volcano in Provence, and then the massive Alps, with altitudes as high as 2,645 meters, challenged the racers. Finally the race headed toward Paris and a July 23rd finish in Paris. Go Lance! To learn more about MODIS, visit the MODIS web. Image by Jacques Descloitres, MODIS Land group, NASA GSFC

  4. France.

    PubMed

    1987-09-01

    In 1986, France had a population of 55,493,000, with an annual growth rate of 0.4%. The infant mortality rate stood at 8.2/1000. Of the work force of 23.8 million, 8.3% were engaged in agriculture, 45.2% were in the industry and commerce sector, and 46.5% were engaged in services. The unemployment rate stood at 10.7%. The country's gross domestic product (GDP) was US$724 billion in 1986, with an average annual growth rate of 2.0%, and per capita income averaged $13,046. France has substantial agricultural resources, a diversified modern industrial system, and a highly skilled labor force. Following the return of a socialist majority in government in 1981, several large manufacturing firms were nationalized along with much of the commercial banking sector. Initial socialist policies were stimulative, relying partly on income redistribution and partly on increased government spending. However, the resultant increase in import demand was not offset by an increased demand French exports. In 1983, an economic stabilization plan of reductions in the budget deficit, involving spending cuts, increased taxes, and tighter monetary and credit policies, was successfully implemented. Although current economic policies should promote stronger growth over the medium to long term, trade competitiveness remains weak and high unemployment is a major social problem. PMID:12177959

  5. France.

    PubMed

    1987-09-01

    In 1986, France had a population of 55,493,000, with an annual growth rate of 0.4%. The infant mortality rate stood at 8.2/1000. Of the work force of 23.8 million, 8.3% were engaged in agriculture, 45.2% were in the industry and commerce sector, and 46.5% were engaged in services. The unemployment rate stood at 10.7%. The country's gross domestic product (GDP) was US$724 billion in 1986, with an average annual growth rate of 2.0%, and per capita income averaged $13,046. France has substantial agricultural resources, a diversified modern industrial system, and a highly skilled labor force. Following the return of a socialist majority in government in 1981, several large manufacturing firms were nationalized along with much of the commercial banking sector. Initial socialist policies were stimulative, relying partly on income redistribution and partly on increased government spending. However, the resultant increase in import demand was not offset by an increased demand French exports. In 1983, an economic stabilization plan of reductions in the budget deficit, involving spending cuts, increased taxes, and tighter monetary and credit policies, was successfully implemented. Although current economic policies should promote stronger growth over the medium to long term, trade competitiveness remains weak and high unemployment is a major social problem.

  6. Overview of 3D Documentation Data and Tools available for Archaeological Researches: case study of the Romanesque Church of Dugny-sur-Meuse (France)

    NASA Astrophysics Data System (ADS)

    Macher, H.; Grussenmeyer, P.; Kraemer, C.; Guillemin, S.

    2015-08-01

    In this paper, the 3D documentation of the full structure of the Romanesque church of Dugny-sur-Meuse is discussed. In 2012 and 2013, a 3D recording project was carried out under the supervision of the Photogrammetry and Geomatics Research Group from INSA Strasbourg (France) in cooperation with C. Kraemer, archaeologist from Nancy (France). The goal of the project was on one hand to propose new solutions and tools to the archaeologists in charge of the project especially for stone by stone measurements. On the other hand, a simplified 3D model was required by the local authorities for communication purposes. To achieve these goals several techniques were applied namely GNSS measurements and accurate traverse networks, photogrammetric recordings and terrestrial laser scanning acquisitions. The various acquired data are presented in this paper. Based on these data, several deliverables are also proposed. The generation of orthoimages from plane as well as cylindrical surfaces is considered. Moreover, the workflow for the creation of a 3D simplified model is also presented.

  7. Palaeo-ecological quality status based on foraminifera of Boulogne-sur-Mer harbour (Pas-de-Calais, Northeastern France) over the last 200 years.

    PubMed

    Francescangeli, F; Armynot du Chatelet, E; Billon, G; Trentesaux, A; Bouchet, V M P

    2016-06-01

    Over the last centuries, coastal areas have experienced dramatic degradations of their environmental quality, which has led to a huge reduction of marine biodiversity. The objective of the present study was to use geochemical parameters and benthic fossil foraminifera to assess environmental changes that have occurred over the last 200 years in a harbour area (Boulogne-sur-Mer, Northern France) heavily modified by human activities. A multidisciplinary approach including major and trace metals, grain-size, total organic carbon and benthic fossil foraminifera, has been performed on a 33-cm long core. The dating was carried out using the activity of (210)Pb and (137)Cs. Embayment of the area and increase of trace metals concentrations induced a shift in benthic communities. Human activities modified a sandy nearshore bank, colonized by typical marine foraminiferal species, such as Cribroelphiudium excavatum, into a sheltered environment, dominated by brackish end-members, such as Haynesina germanica. Along the sedimentary record, the interaction between meiofaunal and geochemical elements made it possible to distinguish between a pre-impacted period and an industrial period. The upper part of the core reflects better ecological conditions, indicating an environmental recovery. Our results provide baselines for future environmental bio-monitoring in the area. PMID:27074196

  8. Assessment by regional modelling of the impact of monopile foundations on the hydrodynamics and sediment transport: case of Courseulles-sur-Mer (France) wind farm

    NASA Astrophysics Data System (ADS)

    Rivier, Aurélie; Bennis, Anne-Claire; Pinon, Grégory; Magar, Vanesa; Gross, Markus

    2015-04-01

    Offshore monopile foundations of wind turbines modify hydrodynamics and sediment transport at local scale and also at regional scale. The aim of this work is to assess these changes and to parametrize them in a regional model. These modifications were previously evaluated using the regional circulation model MARS3D (Lazure and Dumas, 2008) in tests-cases (Rivier et al., 2014) using two approaches: in the first approach, monopiles are explicitly modelled in the mesh as dry cells and in the second approach a sub-grid parametrization which considers the drag force exerted by a monopile on the flow is used. The sub-grid parametrization is improved close to the bed in this paper by adding a drag force term in the momentum equations, source terms in the turbulence model and by increasing the bed shear stress at monopile location. Changes in hydrodynamics regime, especially near-bed, affect sediment transport regime and modifications due to monopiles on sediment dynamics is also investigated using the MARS3D sediment transport module (Le Hir et al., 2011) which solves the advection-diffusion equations. Test-cases are run using hydrodynamical conditions and sediment grain sizes typical from the area located off Courseulles-sur-Mer (Normandy, France) where an offshore wind farm is planned to be built. Velocity, turbulent kinetic energy and bed thickness changes due to the monopile simulated by both approaches are compared to each other and to experimental measurements made in a flume at the University of Caen or to published data (e.g. Roulund et al., 2005; Dargahi,1989). Then the model is applied in a real configuration on an area including the future offshore wind farm of Courseulles-sur-Mer. Four monopiles are represented in the model using both approaches and modifications of the hydrodynamics and sediment transport are assessed along a tidal cycle. Currents increase at the side edge of the monopile and decrease in front of and downstream the monopile. Turbulent kinetic

  9. Statistical properties and time-frequency analysis of temperature, salinity and turbidity measured by the MAREL Carnot station in the coastal waters of Boulogne-sur-Mer (France)

    NASA Astrophysics Data System (ADS)

    Kbaier Ben Ismail, Dhouha; Lazure, Pascal; Puillat, Ingrid

    2016-10-01

    In marine sciences, many fields display high variability over a large range of spatial and temporal scales, from seconds to thousands of years. The longer recorded time series, with an increasing sampling frequency, in this field are often nonlinear, nonstationary, multiscale and noisy. Their analysis faces new challenges and thus requires the implementation of adequate and specific methods. The objective of this paper is to highlight time series analysis methods already applied in econometrics, signal processing, health, etc. to the environmental marine domain, assess advantages and inconvenients and compare classical techniques with more recent ones. Temperature, turbidity and salinity are important quantities for ecosystem studies. The authors here consider the fluctuations of sea level, salinity, turbidity and temperature recorded from the MAREL Carnot system of Boulogne-sur-Mer (France), which is a moored buoy equipped with physico-chemical measuring devices, working in continuous and autonomous conditions. In order to perform adequate statistical and spectral analyses, it is necessary to know the nature of the considered time series. For this purpose, the stationarity of the series and the occurrence of unit-root are addressed with the Augmented-Dickey Fuller tests. As an example, the harmonic analysis is not relevant for temperature, turbidity and salinity due to the nonstationary condition, except for the nearly stationary sea level datasets. In order to consider the dominant frequencies associated to the dynamics, the large number of data provided by the sensors should enable the estimation of Fourier spectral analysis. Different power spectra show a complex variability and reveal an influence of environmental factors such as tides. However, the previous classical spectral analysis, namely the Blackman-Tukey method, requires not only linear and stationary data but also evenly-spaced data. Interpolating the time series introduces numerous artifacts to the

  10. Enquetes sur les transformations economiques et sociales de la France: Rapports des groupes d'etudes. Travaux pratiques de civilisation, Rennes-1968 (Investigations of Economic and Social Change in France: Reports of Study Groups. Applied Studies in Civilization, Rennes-1968).

    ERIC Educational Resources Information Center

    Philip, Sister Marie, Ed.; And Others

    Investigations into the sociocultural pattern of life in Rennes, France, are presented in this study. Topics include: (1) the modern family in Rennes, (2) the university generation, (3) social growth and expansion, (4) life in the Maurepas quarter, (5) cultural development, (6) shops and shopkeepers, (7) French eating habits, (8) rural living, and…

  11. Construction de la Technologie pour l'ecole moyenne en France: un apercu historique (Construction of Technology for the Average School in France: An Historic Approach).

    ERIC Educational Resources Information Center

    Lebeaume, Joel

    2003-01-01

    Presents tools for objectifying technological education as it has been approached in the form of disciplines for French children ages 11-15 since 1960. Characterizes provisionally stabilized disciplines and identifies their historical development. Identifies four distinct methods that give evidence of the instability affecting the framework of…

  12. Le genre Cainotherium Bravard, 1828 en Limagne (Allier, France): perspectives nouvelles sur le dimorphisme sexuel et le régime alimentaireThe genus Cainotherium Bravard, 1828 in Limagne (Allier, France): new prospects on sexual dimorphism and food habits.

    NASA Astrophysics Data System (ADS)

    Berthet, Didier; Hugueney, Marguerite

    2000-07-01

    In some Oligo-Miocene continental localities from Limagne (Allier, France) two Cainotherium populations, having an identical dental morphology, can be differentiated with the help of measurements. Various authors suggest that these two populations correspond either to two distinct species or to the expression of sexual dimorphism. It has been shown that the two forms of Cainotherium recently found in the same deposit and studied with new methods (mandibular analysis, SEM microphotographs) correspond to two species with different diets.

  13. Benthic trophic network in the Bay of Banyuls-sur-Mer (northwest Mediterranean, France): An assessment based on stable carbon and nitrogen isotopes analysis

    NASA Astrophysics Data System (ADS)

    Carlier, Antoine; Riera, Pascal; Amouroux, Jean-Michel; Bodiou, Jean-Yves; Grémare, Antoine

    2007-03-01

    The benthic trophic network in the Bay of Banyuls-sur-Mer was studied through the carbon and nitrogen isotopic characterization of a large set of soft-bottom macrobenthic invertebrates, fishes and potential food sources. Continental inputs as well as seagrass meadows did not contribute significantly to this benthic trophic network as indicated by: (1) the difference between their δ 13C signatures (respectively -28.4‰ and -9.5‰) and those of sampled animals (between -21.0‰ and -14.6‰); and (2) their low inputs to the bay. Benthic primary consumers fed mostly on surface sediment organic matter (SSOM), which tightly interacts with suspended particulate organic matter (SPOM) and sedimenting organic matter (STOM) due to sediment resuspension. Our results also suggest the occurrence of a transfer between marine SPOM and some invertebrates (e.g. Veretillum cynomorium) and fishes (e.g. Boops boops and Spicara melanurus) through zooplankton. Moreover, the different types of primary consumers (i.e., suspension-feeders, interface-feeders, surface deposit-feeders and subsurface deposit-feeders) preferentially used distinct fractions of the heterogeneous SPOM-STOM-SSOM pool. These differences were mostly related with feeding depth and resulted in distinct isotopic signatures. Differences in the stable isotopic ratios of suspension and interface-feeders could also partly reflect the use of microphytobenthos by the later. Assuming a 15N-enrichment factor of 3.4‰ between the lower and upper ranges of two successive trophic levels, we estimated that the benthic food web of the Bay of Banyuls-sur-Mer was composed of 4 trophic levels. The comparison with our δ 13C values suggests that the whole trophic food chain is affected by continental inputs at the immediate vicinity of the Rhône River mouth even though these effects are maximal for deposit-feeding and carnivorous polychaetes.

  14. Carbonate chemistry and air-sea CO2 flux at a fixed point in a NW Mediterranean Bay, Villefranche-sur-Mer, France

    NASA Astrophysics Data System (ADS)

    De Carlo, E. H.; Mousseau, L.; Passafiume, O.; Drupp, P. S.; Gattuso, J.

    2011-12-01

    The purpose of the Service d'Observation de la Rade de Villefranche-sur-Mer (SO-RADE) is to study the temporal variability of hydrological conditions as well as the abundance and composition of holo- and meroplankton at a fixed station in the bay of Villefranche-sur-Mer, North West Mediterranean. The weekly data collected at this site, designated as "Point B (43° 41.10'N - 7° 18.94'E), since 1957 are recognized as a long-term time series describing the evolution of the hydrological conditions in a coastal environment. Since 2007, historical measurements of hydrological and biological conditions have been complemented by measurements of the CO2-carbonate system parameters. In this contribution we present CO2-carbonate system parameters and ancillary data for the period 2007-2010. The data are evaluated in the context of the physical and biogeochemical processes that contribute to the fluxes of CO2 between the ocean and atmosphere. Seasonal cycles of seawater pCO2 are controlled principally by variations in temperature, showing maxima in the summer and minima during the winters. Normalization of pCO2 to the mean seawater temperature (18oC) results in an apparent reversal of the seasonal cycle with maxima observed in the winters and minima in the summers, consistent with a control of pCO2 by primary productivity. Calculations of "instantaneous fluxes" of CO2 between the ocean and atmosphere show this area to be primarily a weak source of CO2 to the atmosphere during the summer and a weak sink during the winter and near neutral overall (range: -0.3 to +0.3 mmol CO2 m-2 h-1, average: 0.02 mmol CO2 m-2 h-1). We will also provide projections of errors incurred from the estimation of annualized fluxes of CO2 based on weekly measurements relative to daily and high-frequency (3 h) data such as those obtained at the Hawaii Kilo Nalu coastal time series station, which shows similar behavior to the Point B location despite significant differences in climate and hydrological

  15. France`s nuclear dilemmas

    SciTech Connect

    Yost, D.S.

    1996-01-01

    Ignoring worldwide protests, France conducted the first of several scheduled nuclear tests in September. The controversy has overshadowed France`s more important nuclear challenges: maintaining a strong deterrent under a test ban, moving ahead with its proposals for {open_quotes}Europeanization{close_quotes} of that deterrent, and developing a consensus on how nuclear threats should be used in response to those who would brandish other weapons of mass destruction. 1 fig.

  16. Synchrotron X-ray microanalysis and imaging of synthetic biological calcium carbonate in comparison with archaeological samples originating from the Large cave of Arcy-sur-Cure (28000-24500 BP, Yonne, France).

    PubMed

    Chalmin, Emilie; Reiche, Ina

    2013-12-01

    Biosynthetic calcite samples were investigated using combined synchrotron X-ray microspectroscopy mapping. These samples were prepared with bacteria isolated from the Large cave of Arcy-sur-Cure in which prehistoric figures are masked by an opaque calcite layer. The biotic or abiotic origin of this layer is the issue of the present work. As previously known, a large community of bacteria may be involved in the CaCO3 formation in caves. A mixture of calcite/vaterite was obtained from bacteria isolated from the cave. Therefore, we can offer conclusions on their calcifying capability. The rare presence of vaterite in cave environments may be treated as a marker of biotic carbonate formations. Moreover, an amorphous calcium phosphate phase was present in the form of a calcite/vaterite mixture in the biotic model samples. This mixture of phases could be used as a tracer of the biotic process of CaCO3 formation. These biotic tracer phases were not identified using the applied analytical methods in the natural samples taken from the opaque calcite layers that covered the prehistoric figures of the Large cave. In this case, based on the obtained results, the biotic calcite formation process is likely to be considered as an undetectable effect at minimum.

  17. Sur le fonctionnement d'un ouvrage de grande hydraulique antique, l'aqueduc de Nîmes et le pont du Gard (Languedoc, France)The hydraulic engineering of the ancient aqueduct of Nimes and the Pont du Gard (Languedoc, France).

    NASA Astrophysics Data System (ADS)

    Bossy, Gonzague; Fabre, Guilhem; Glard, Yves; Joseph, Christian

    2000-06-01

    The aqueduct at Nimes is the best known of all the Gallo-Roman aqueducts in France. Interdisciplinary, permanent and recent research (topography, karstic hydrology, hydraulic modelling...) provides a new insight into its functioning. It was fed exclusively by the Eure karstic springs (Uzes, Gard) and the water passed through a channel with successive segmented reaches and horizontal banks. This made it possible to regulate the flow according to demand and to control it through small hydraulic structures directly connected to the channel. The maximum discharge ranged from 200 to 400 L·s -1.

  18. Hurricanes Frances and Ivan

    Atmospheric Science Data Center

    2014-05-15

    article title:  Cloud Height Maps for Hurricanes Frances and Ivan     ... predict the intensity and amount of rainfall associated with hurricanes still requires improvement, especially on the 24 to 48 hour ...

  19. Détermination d'un pǒle paléomagnétique et mise en évidence d'aimantations à polarité normale sur les formations du Permien supérieur du Massif des Maures (France)

    NASA Astrophysics Data System (ADS)

    Merabet, N.; Daly, L.

    1986-10-01

    Des roches sédimentaires du Massif des Maures (latitude: 43,4°N, longitude: 6,3°E), appartenantàla famille des pélites et dont l'ǎge bien préciséest Permian supérieur (Thuringien), ontétéétudiées par analyse thermique et par champs alternatifs. La direction moyenne de l'aimantation caractéristique, obtenueàpartir de 103échantillons, en donnant le měme poids aux 10 sites, est définie par D = -164°, I = -14° et α 95 = 4° , et le pǒle paléomagnétique Nord correspondant est situéà51°N, 161°E avec A 95 = 3,5° . Ce pǒle est très proche de la partie 230-250 Ma de la courbe de migration polaire européenne. Il estégalement proche des pǒles du Permien supérieur obtenus par Zijderveld en Estérel oriental, et de ceux d'U.R.S.S., obtenus sur les formations rouges de la Volga dont l'ǎge est Tatarien supérieur. Ce résultat montre qu'il n'y a pas eu de déplacement tectonique important dans la région depuis le Permien, et le pǒle peut doncětre considérécomme une nouvelle contribution. Une polariténormale a puětre correctement isolée sur 20% deséchantillons. Ce résultat, très similaireàcelui obtenu sur les formations rouges du Permien supérieur de la Volga, apporte un nouvel argument en faveur de la solution qui situe la limite supérieure de l'intervalle Kiaman au début du Thuringien.

  20. France declares energy independence

    SciTech Connect

    Mills, M.P.; Starr, R.

    1983-03-01

    France has adhered to its policy of pursuing nuclear energy, using the same pressurized light-water reactor technology developed in the US, and going beyond to develop an operating breeder reactor, the Phenix. Pride and pragmatism, of which France has a full share, and petroleum, of which she has none, are the combination which has made the French nuclear program successful. The major difference between the French and US nuclear programs is institutional and political. The author concludes from his comparison that the US approach of private development and regulation is not appropriate. (DCK)

  1. Ethics committees in France.

    PubMed

    Isambert, F A

    1989-08-01

    Leading biologists and physicians in France have been considering bioethical problems for several decades. In 1983 an important new forum for bioethical discussion in France was created, with the establishment of the Comité Consultatif National d'Ethique pour les Sciences de la Vie et de la Santé (C.C.N.E.). This committee has produced numerous important opinions and reports on such topics as research involving human subjects, fetal tissue research, and the new reproductive technologies. At the local level the discussion of bioethical questions is carried on by ethics committees, which are charged with the responsibility of reviewing research protocols.

  2. France. [CME Country Reports].

    ERIC Educational Resources Information Center

    Council of Europe, Strasbourg (France). Documentation Center for Education in Europe.

    In France, the 1882 Compulsory Education Act includes both French and foreign children. Since then, the need to go further than this general principle of non-discrimination and to undertake specific action for immigrants, both adults and children, has been recognized. Since 1970, the Ministry of Education has been directly responsible for this…

  3. Urban Sociology in France.

    ERIC Educational Resources Information Center

    Amiot, Michel

    1986-01-01

    Divides the history of urban sociology in France into three periods: (1) functionalism, which lasted from 1910 until the 1960s, (2) neo-Marxist socioeconomics lasting from 1968 until 1979, and (3) anthropological approach which is still dominant. Reviews theoretical perspectives and research characteristic of each period. (JDH)

  4. Tidal Power in France

    SciTech Connect

    Frau, J.P. )

    1993-03-01

    This presentation discusses the tidal power resource of France and the successes of the La Rance Plant. The topics of the presentation include power generation, adaptation of output to grid requirements, plant installation, environmental factors, La Rance success, and a review of major world wide tidal energy projects in the UK, Canada, South Korea, India, and Argentina.

  5. Country Profiles. France.

    ERIC Educational Resources Information Center

    Bourgeois-Pichat, Jean

    A profile of France is sketched in this paper. Emphasis is placed on the nature, scope, and accomplishments of population activities in the country. Topics and sub-topics include: (1) location and description of the country; (2) population--size, growth patterns, age structure, urban/rural distribution, ethnic and religious composition, education,…

  6. Chagas disease, France.

    PubMed

    Lescure, François-Xavier; Canestri, Ana; Melliez, Hugues; Jauréguiberry, Stéphane; Develoux, Michel; Dorent, Richard; Guiard-Schmid, Jean-Baptiste; Bonnard, Philippe; Ajana, Faïza; Rolla, Valeria; Carlier, Yves; Gay, Frederick; Elghouzzi, Marie-Hélène; Danis, Martin; Pialoux, Gilles

    2008-04-01

    Chagas disease (CD) is endemic to Latin America; its prevalence is highest in Bolivia. CD is sometimes seen in the United States and Canada among migrants from Latin America, whereas it is rare in Europe. We report 9 cases of imported CD in France from 2004 to 2006.

  7. Traveling in France.

    ERIC Educational Resources Information Center

    Philyaw, Henry; And Others

    This minicourse guide for teachers of French is intended to help motivate and prepare students for travel in France. Activities are outlined in eleven related areas, including (1) planning for the trip, (2) currency, (3) going through customs, (4) tipping, (5) shopping, (6) guided tours, (7) touring on your own, (8) social life and entertainment,…

  8. Nouveaux éléments sur la structure et le fonctionnement hydrogéologique du plateau basaltique de l'Aubrac (Massif central, France). Première évaluation des potentialités en eau souterraine

    NASA Astrophysics Data System (ADS)

    Bourlier, Pierre-Yves; Lachassagne, Patrick; Desprats, Jean-François; Gille, Emmanuel

    2005-05-01

    In volcanic areas, the quality of the geological data at the various scales is of paramount importance for the estimation of aquifer potentialities and thus for groundwater exploitation. Geological and hydrogeological investigation (synthesis of existing data, field geological observations, reconstruction of the infra-volcanic morphology, stream gauging, field hydrogeology, etc.) have been performed on the 450-km 2 Aubrac basaltic plateau (Massif Central, France). These results allow us to specify the hydrological structure and functioning of this volcanic plateau that were quite unknown before. It is mainly constituted by the piling up of lava flows resting on a plutonic and metamorphic substratum. This volcanic unit constitutes an aquifer of regional importance whose groundwater resources are currently underexploited. These results allow us to delineate zones and strategies for priority hydrogeological prospecting. To cite this article: P.-Y. Bourlier et al., C. R. Geoscience 337 (2005).

  9. Report from France

    PubMed Central

    Régnier, François; Rouzioux, Jean-Marc

    1983-01-01

    The authors consider four aspects of contemporary medical ethics in France: abortion and contraception; artificial insemination; suicide and euthanasia, and drug trials on healthy human volunteers, and then outline the various ethical codes which apply to French doctors. Many in France who accept technological progress are unwilling or unable to acknowledge the impact upon medical ethics of this progress. The conflict is epitomised by the new role being demanded from the doctor. Where formerly he was regarded as the guardian of traditional values today he is urged to adapt, to change, to take account of the technological innovations in medicine. `In such a situation,' the authors ask, `how is it possible to avoid a feeling of uneasiness?' PMID:6352945

  10. [Primary care in France].

    PubMed

    Sánchez-Sagrado, T

    2016-01-01

    The poor planning of health care professionals in Spain has led to an exodus of doctors leaving the country. France is one of the chosen countries for Spanish doctors to develop their professional career. The French health care system belongs to the Bismarck model. In this model, health care system is financed jointly by workers and employers through payroll deduction. The right to health care is linked to the job, and provision of services is done by sickness-funds controlled by the Government. Primary care in France is quite different from Spanish primary care. General practitioners are independent workers who have the right to set up a practice anywhere in France. This lack of regulation has generated a great problem of "medical desertification" with problems of health care access and inequalities in health. French doctors do not want to work in rural areas or outside cities because "they are not value for money". Medical salary is linked to professional activity. The role of doctors is to give punctual care. Team work team does not exist, and coordination between primary and secondary care is lacking. Access to diagnostic tests, hospitals and specialists is unlimited. Duplicity of services, adverse events and inefficiencies are the norm. Patients can freely choose their doctor, and they have a co-payment for visits and hospital care settings. Two years training is required to become a general practitioner. After that, continuing medical education is compulsory, but it is not regulated. Although the French medical Health System was named by the WHO in 2000 as the best health care system in the world, is it not that good. While primary care in Spain has room for improvement, there is a long way for France to be like Spain.

  11. [Primary care in France].

    PubMed

    Sánchez-Sagrado, T

    2016-01-01

    The poor planning of health care professionals in Spain has led to an exodus of doctors leaving the country. France is one of the chosen countries for Spanish doctors to develop their professional career. The French health care system belongs to the Bismarck model. In this model, health care system is financed jointly by workers and employers through payroll deduction. The right to health care is linked to the job, and provision of services is done by sickness-funds controlled by the Government. Primary care in France is quite different from Spanish primary care. General practitioners are independent workers who have the right to set up a practice anywhere in France. This lack of regulation has generated a great problem of "medical desertification" with problems of health care access and inequalities in health. French doctors do not want to work in rural areas or outside cities because "they are not value for money". Medical salary is linked to professional activity. The role of doctors is to give punctual care. Team work team does not exist, and coordination between primary and secondary care is lacking. Access to diagnostic tests, hospitals and specialists is unlimited. Duplicity of services, adverse events and inefficiencies are the norm. Patients can freely choose their doctor, and they have a co-payment for visits and hospital care settings. Two years training is required to become a general practitioner. After that, continuing medical education is compulsory, but it is not regulated. Although the French medical Health System was named by the WHO in 2000 as the best health care system in the world, is it not that good. While primary care in Spain has room for improvement, there is a long way for France to be like Spain. PMID:26304179

  12. Pharmacy Education in France

    PubMed Central

    Bourdon, Olivier; Ekeland, Catherine

    2008-01-01

    In France, to practice as a pharmacist, one needs a “diplome d'état de Docteur en Pharmacie” This degree is awarded after 6 or 9 years of pharmacy studies, depending on the option chosen by the student. The degree is offered only at universities and is recognized in France as well as throughout the European Union. Each university in France is divided into faculties called Unité de Formation et de Recherche (UFR). There are 24 faculties of pharmacy or UFRs de pharmacie. A national committee develops a pharmacy education program at the national level and each faculty adapts this program according to its specific features and means (eg, faculty, buildings). The number of students accepted in the second year is determined each year by a Government decree (numerus clausus). Successive placements, totalling 62 weeks, progressively familiarize the student with professional practice, and enable him/her to acquire the required competencies, such as drug monitoring and educating and counselling patients. Challenges facing community pharmacies in the next 10 years are patient education, home health care, and orthopaedics; in hospital pharmacies, empowering pharmacists to supervise and validate all prescriptions; and finally, research in pharmacy practice. PMID:19325952

  13. Pharmacy education in France.

    PubMed

    Bourdon, Olivier; Ekeland, Catherine; Brion, Françoise

    2008-12-15

    In France, to practice as a pharmacist, one needs a "diplome d'état de Docteur en Pharmacie" This degree is awarded after 6 or 9 years of pharmacy studies, depending on the option chosen by the student. The degree is offered only at universities and is recognized in France as well as throughout the European Union. Each university in France is divided into faculties called Unité de Formation et de Recherche (UFR). There are 24 faculties of pharmacy or UFRs de pharmacie. A national committee develops a pharmacy education program at the national level and each faculty adapts this program according to its specific features and means (eg, faculty, buildings). The number of students accepted in the second year is determined each year by a Government decree (numerus clausus). Successive placements, totalling 62 weeks, progressively familiarize the student with professional practice, and enable him/her to acquire the required competencies, such as drug monitoring and educating and counselling patients. Challenges facing community pharmacies in the next 10 years are patient education, home health care, and orthopaedics; in hospital pharmacies, empowering pharmacists to supervise and validate all prescriptions; and finally, research in pharmacy practice.

  14. Petroleum statistics in France

    SciTech Connect

    De Saint Germain, H.; Lamiraux, C.

    1995-08-01

    33 oil companies, including Elf, Exxon, Agip, Conoco as well as Coparex, Enron, Hadson, Midland, Hunt, Canyon and Union Texas are present in oil and gas exploration and production in France. The production of oil and gas in France amounts to some 60,000 bopd of oil and 350 MMcfpd of marketed natural gas each year, which still accounts for 3.5% and 10% for French domestic needs, respectively. To date, 166 fields have been discovered, representing a total reserve of 3 billion bbl of crude oil and 13 trillion cf of raw gas. These fields are concentrated in two major onshore sedimentary basins of Mesozoic age, which are the Aquitaine basin and the Paris basin. The Aquitaine basin should be subdivided into two distinct domains: The Parentis basin where the largest field Parentis was discovered in 1954 with still production of about 3700 bopd of oil and where Les Arbouslers field, discovered at the end of 1991, is currently producing about 10,000 bopd of oil. The northern Pyrenees and their foreland, where the Lacq field, discovered in 1951, has produced about 7.7 tcf of gas since 1957, and is still producing 138 MMcfpd. In the Paris basin, the two large oil fields are Villeperclue discovered in 1982 by Triton and Total, and Chaunoy, discovered in 1983 by Essorep, which are still producing about 10,000 and 15,000 bopd, respectively. The last significantly sized discovery occurred in 1990 with Itteville by Elf Aquitaine which is currently producing 4,200 bopd. The poster shows statistical data related to the past 20 years of oil and gas exploration and production in France.

  15. Les torsions sur testicules cryptorchides

    PubMed Central

    Gharbi, Mohamed; Amri, Najmeddine; Chambeh, Wahib; Braiek, Salem; Kamel, Rafik El

    2010-01-01

    Résumé But : La cryptorchidie est une pathologie assez fréquente en urologie. Elle est associée à un risque élevé d’infertilité et de dégénérescence. Elle semble aussi être associée à un risque important de torsion. Cette entité est très peu abordée dans la littérature. Nous rapportons tous les cas de torsion sur testicule cryptorchide observés à notre service dans le but de mieux caractériser cette pathologie et de réduire ainsi le taux d’orchidectomies. Méthodologie : Il s’agit d’une étude rétrospective portant sur tous les cas de torsion sur testicule cryptorchide opérés dans notre service d’urologie entre 1999 et 2007. Les patients ont fait l’objet d’une description basée sur le résumé de leurs observations. Résultats : Les patients étaient âgés de 7 mois à 39 ans. La torsion touchait le testicule droit dans 53 % des cas. Le tableau clinique comportait une douleur au niveau de la région inguinale d’apparition soudaine avec une masse sous-cutanée inflammatoire et douloureuse à ce niveau et surtout un hémiscrotum homolatéral vide. Dans 60 % des cas, le diagnostic était tardif et une orchidectomie a été réalisée. Dans les autre cas, un abaissement du testicule a été réalisé avec orchidopexie controlatéral dans le même temps opératoire. Conclusion : Bien qu’il s’agisse d’une pathologie peu courante, la torsion sur testicule cryptorchide doit être étudiée davantage. Le diagnostic précoce permettra de sauver et d’abaisser le testicule et faciliter ainsi le dépistage d’une éventuelle dégénérescence. PMID:21191497

  16. Medicolegal anthropology in France.

    PubMed

    Işcan, M Y; Quatrehomme, G

    1999-03-15

    Medicolegal anthropology has a very long history in France. Basic studies on human skeletal remains started as early as the 18th century. The 19th century produced many medical theses and research papers on age, sex, as well as stature estimation. The research proliferated in the first 60 years of the 20th century, much of which is still in use in France and abroad. The later half of the 20th century, however, was dormant in research on human skeletal biology at a time when forensic anthropology was becoming an active field worldwide. In the last decade, medicolegal anthropology took a different perspective, independent of its traditional roots. Research and practice have both been in the professional domain of forensic physicians unlike the situation in many other countries. Population based studies requiring large databases or skeletal collections have diminished considerably. Thus, most research has been on factors of individualization such as trauma, time since death, crime scene investigation, and facial reconstruction. It is suggested that there is a need for cooperation between the forensic physician and anthropologist to further research. This also encourages anthropologists to carry out research and practice that can fulfill the needs of the medicolegal system of the country. PMID:10356772

  17. Battle of France WWII

    NASA Astrophysics Data System (ADS)

    Gadhath, Arpitha Rao

    The purpose of this thesis is to build an interactive Geographical Information System (GIS) tool, relating to the series of events that occurred during the Battle of France World War II. The tool gives us an insight about the countries involved in the battle, their allies and their strategies. This tool was created to use it as a one stop source of information regarding all the important battles that took place, which lead to the fall of France. The tool brings together the maps of all the countries involved. Integrated with each map is the data relevant to that map. The data for each country includes the place of attack, the strategies used during the attack, and the kind of warfare. The tool also makes use of HTML files to give all the information, along with the images from the time of the war and a footage which explains everything about the particular battle. The tool was build using JAVA, along with the use of MOJO (Map Objects Java Objects) to develop Maps of each of the countries. MOJO is developed by ESRI (Environmental Science Research Institute) which makes it easier to add data to the maps. It also makes highlighting important information easier making use of pop-up windows, charts and infographics. HTML files were designed making use of the open-source template developed by Bootstrap. The tool is built in such a way that the interface is simple and easy for the user to use and understand.

  18. France: late abortion.

    PubMed

    Gaudry, D; Sadan, G

    1989-01-01

    In France, under the terms of a law passed by Parliament in 1975, a woman may have an abortion up to 12 weeks of pregnancy if she is a French resident and, in the event that she is a minor, she has parental consent. The woman must also have 2 medical consultations, a week apart. The woman is reimbursed by the state up to 70% of the cost of the abortion. After 12 weeks, abortion, except for therapeutic abortion, under the terms of Article 317 of the Criminal Code, is a crime, punishable by 6 months to 10 years in prison, a fine of between 1800 and 250,000 Francs, and loss of professional license. Moreover, Article 647 of the Health Code bans any advertising, incitement or propaganda for abortion or abortion-inducing products. Many French women go to Britain or Holland for abortions after 12 weeks, but they face the financial burden of traveling as well as the difficulties of getting help in a strange country and the stigma of having done something illegal. The Mouvement Francais pour le Planning Familial, which won the legalization of contraception in 1967, is now fighting for legal abortion as well as the distribution of information about sexuality, contraception, and abortion in the schools. 2 charges of incitement to abortion have been brought against the organization.

  19. Women in physics in France

    NASA Astrophysics Data System (ADS)

    Pierron-Bohnes, Véronique

    2015-12-01

    We present six associations and entities working in France on issues of women in physics: the Women and Physics Commission, French Physical Society; Women in Nuclear (WiN) France; Women and Science Association; Mission for the Place of Women at CNRS; Parity, Diversity, and Women Network, CEA; and the Network of University Equality-Diversity Representatives.

  20. Old Age Policy in France.

    ERIC Educational Resources Information Center

    Guillemard, Anne-Marie

    Old-age policy in France has evolved historically in three critical dimensions that also correspond generally to post-World War II developments in France: the right to retirement (pensions); improved living conditions (e.g., autonomy, housing); and continued participation in the labor force. The last focus is currently a controversial one, given…

  1. Women in physics in France

    SciTech Connect

    Pierron-Bohnes, Véronique

    2015-12-31

    We present six associations and entities working in France on issues of women in physics: the Women and Physics Commission, French Physical Society; Women in Nuclear (WiN) France; Women and Science Association; Mission for the Place of Women at CNRS; Parity, Diversity, and Women Network, CEA; and the Network of University Equality-Diversity Representatives.

  2. Frances Mary hodgkins.

    PubMed

    Laurie, A J

    2001-01-01

    SUMMARY Frances Hodgkins was one of a number of expatriate New Zealanders during the early twentieth century who lived in Britain or Europe, where it was easier to find supportive friendship circles for their lives as artists or as people attracted to their own sex. In this article, I explore the primacy of women in Hodgkins' life and read this as lesbian and argue that many of these relationships were sexual, from the evidence of her letters, which suggest that she moved in lesbian worlds of work and friendship. I also discuss the financial and emotional support given by her male homosexual as well as her lesbian friends who made her life as an artist possible.

  3. Groundwater management in France

    SciTech Connect

    Margat, J. )

    1987-01-01

    Groundwater, like other extensive natural and renewable resources, easily accessible and, at the same time, vulnerable, has to be managed so as to reconcile the unique resource with its many users, and its long-term preservation with short-term utilization requirements. Under the natural, legal, and economic conditions prevailing in France, where groundwater constitutes a large part of water production and resources, where there are tens of thousands of economic developers and users of a few hundred natural groundwater management units, such management concerns these users as well as the public and collective authorities that control the users activities for the common present and future good at all. Legislative, financial, and educational means are applied simultaneously to preserve and protect the quality and quantity of the groundwater and at times to encourage its use and stimulate its development.

  4. The "Casa" of Sevres, France.

    ERIC Educational Resources Information Center

    Waltuch, Margot

    1996-01-01

    Discusses the author's teaching experiences during the 1930s at "La Maison des Enfants," a Montessori school in Sevres, France. Provides photographs and descriptions of the school day, outdoor activities, gardening, cooking and eating, practical activities, and creative activities. (MDM)

  5. National Report France: The French Balloon Programme 2013-2016

    NASA Astrophysics Data System (ADS)

    Dubourg, V.; Vassaux, D.; Vargas, A.; Cocquerez, P.; Louvel, S.; Douchin, F.; Saccocio, M.; Mirc, F.

    2015-09-01

    With over 50 years' experience in the field, the French Centre National dEtudes Spatiales (CNES) goes on supporting a significant scientific ballooning program. In particular so because balloons still give a unique access to near space science. Over the past 6 years, most of the systems, beginning by the Zero Pressure Balloons, had to be renewed to comply with more stringent Safety constraints and to growing performance and reliability requirements from the scientific missions. This paper will give an overview of the CNES new capabilities and services for operational balloon activities, and their availability status. The scientific launch campaigns of the past two years will be presented. A focus will be made on the results of the Stratoscience 2014 flight campaign from Timmins, Ontario, using the NOSYCA command and control system for zero pressure balloons, qualified in 2013. The ChArMEx campaign (Chemistry-AeRosol Mediterranean Experiment) performed in 2013 from the Baleares islands and from the south of France, with Boundary Layer Pressurized Balloons will also be presented as well as the LOAC-VOLTAIRE experiment, carried out from Aire-sur-l'Adour (France), through the flights of 20 instrumented light expandable balloons. An outlook of the new stratospheric long duration flight systems currently studied at CNES will be given. The scientific launch campaigns and the main payloads in the study for the near future will also be presented.

  6. Beginning of viniculture in France

    PubMed Central

    McGovern, Patrick E.; Luley, Benjamin P.; Rovira, Nuria; Mirzoian, Armen; Callahan, Michael P.; Smith, Karen E.; Hall, Gretchen R.; Davidson, Theodore; Henkin, Joshua M.

    2013-01-01

    Chemical analyses of ancient organic compounds absorbed into the pottery fabrics of imported Etruscan amphoras (ca. 500–475 B.C.) and into a limestone pressing platform (ca. 425–400 B.C.) at the ancient coastal port site of Lattara in southern France provide the earliest biomolecular archaeological evidence for grape wine and viniculture from this country, which is crucial to the later history of wine in Europe and the rest of the world. The data support the hypothesis that export of wine by ship from Etruria in central Italy to southern Mediterranean France fueled an ever-growing market and interest in wine there, which, in turn, as evidenced by the winepress, led to transplantation of the Eurasian grapevine and the beginning of a Celtic industry in France. Herbal and pine resin additives to the Etruscan wine point to the medicinal role of wine in antiquity, as well as a means of preserving it during marine transport. PMID:23733937

  7. Beginning of Viniculture in France

    NASA Technical Reports Server (NTRS)

    McGovern, Patrick E.; Luley, Benjamin P.; Rovira, Nuria; Mirzoian, Armen; Callahan, Michael P.; Smith, Karen F.; Hall, Gretchen R.; Davidson, Theodore; Henkin, Joshua M.

    2013-01-01

    Chemical analyses of ancient organic compounds absorbed into the pottery fabrics of imported Etruscan amphoras (ca. 500-475 B.C.) and into a limestone pressing platform (ca. 425-400 B.C.) at the ancient coastal port site of Lattara in southern France provide the earliest biomolecular archaeological evidence for grape wine and viniculture from this country, which is crucial to the later history of wine in Europe and the rest of the world. The data support the hypothesis that export of wine by ship from Etruria in central Italy to southern Mediterranean France fueled an ever-growing market and interest in wine there, which, in turn, as evidenced by the winepress, led to transplantation of the Eurasian grapevine and the beginning of a Celtic industry in France. Herbal and pine resin additives to the Etruscan wine point to the medicinal role of wine in antiquity, as well as a means of preserving it during marine transport.

  8. Beginning of viniculture in France.

    PubMed

    McGovern, Patrick E; Luley, Benjamin P; Rovira, Nuria; Mirzoian, Armen; Callahan, Michael P; Smith, Karen E; Hall, Gretchen R; Davidson, Theodore; Henkin, Joshua M

    2013-06-18

    Chemical analyses of ancient organic compounds absorbed into the pottery fabrics of imported Etruscan amphoras (ca. 500-475 B.C.) and into a limestone pressing platform (ca. 425-400 B.C.) at the ancient coastal port site of Lattara in southern France provide the earliest biomolecular archaeological evidence for grape wine and viniculture from this country, which is crucial to the later history of wine in Europe and the rest of the world. The data support the hypothesis that export of wine by ship from Etruria in central Italy to southern Mediterranean France fueled an ever-growing market and interest in wine there, which, in turn, as evidenced by the winepress, led to transplantation of the Eurasian grapevine and the beginning of a Celtic industry in France. Herbal and pine resin additives to the Etruscan wine point to the medicinal role of wine in antiquity, as well as a means of preserving it during marine transport.

  9. Pockmarks off Big Sur, California

    USGS Publications Warehouse

    Paull, C.; Ussler, W.; Maher, N.; Greene, H. Gary; Rehder, G.; Lorenson, T.; Lee, H.

    2002-01-01

    A pockmark field was discovered during EM-300 multi-beam bathymetric surveys on the lower continental slope off the Big Sur coast of California. The field contains ??? 1500 pockmarks which are between 130 and 260 m in diameter, and typically are 8-12 m deep located within a 560 km2 area. To investigate the origin of these features, piston cores were collected from both the interior and the flanks of the pockmarks, and remotely operated vehicle observation (ROV) video and sampling transects were conducted which passed through 19 of the pockmarks. The water column within and above the pockmarks was sampled for methane concentration. Piston cores and ROV collected push cores show that the pockmark field is composed of monotonous fine silts and clays and the cores within the pockmarks are indistinguishable from those outside the pockmarks. No evidence for either sediment winnowing or diagenetic alteration suggestive of fluid venting was obtained. 14C measurements of the organic carbon in the sediments indicate continuous sedimentation throughout the time resolution of the radiocarbon technique ( ??? 45000 yr BP), with a sedimentation rate of ??? 10 cm per 1000 yr both within and between the pockmarks. Concentrations of methane, dissolved inorganic carbon, sulfate, chloride, and ammonium in pore water extracted from within the cores are generally similar in composition to seawater and show little change with depth, suggesting low biogeochemical activity. These pore water chemical gradients indicate that neither significant accumulations of gas are likely to exist in the shallow subsurface ( ??? 100 m) nor is active fluid advection occurring within the sampled sediments. Taken together the data indicate that these pockmarks are more than 45000 yr old, are presently inactive, and contain no indications of earlier fluid or gas venting events. ?? 2002 Elsevier Science B.V. All rights reserved.

  10. Discovery of a thyreophoran trackway in the hettangian of central france

    NASA Astrophysics Data System (ADS)

    Le Lœuff, Jean; Lockley, Martin; Meyer, Christian; Petit, Jean-Pierre

    1999-02-01

    Well-preserved dinosaur footprints have been excavated in the Hettangian of Corgnac-sur-l'Isle (Dordogne, France). They are attributed to a large thyreophoran dinosaur and clearly show a stegosaur-like 2-2-2 phalangeal formula for pes digits II, III and IV. Pes digit I is variably impressed. This is the first Early Jurassic thyreophoran trackway ever discovered, and the largest known ornithischian tracks of this period. It definitely shows that primitive thyreophorans were quadrupedal and suggests that phalangeal reduction preceded digital reduction in the evolution of advanced thyreophorans.

  11. Pyemotes ventricosus Dermatitis, Southeastern France

    PubMed Central

    Blanc-Amrane, Véronique; Bahadoran, Philippe; Caumes, Eric; Marty, Pierre; Lazar, Mariléna; Boissy, Christian; Desruelles, François; Izri, Arezki; Ortonne, Jean-Paul; Counillon, Evelyne; Chosidow, Olivier; Delaunay, Pascal

    2008-01-01

    We investigated 42 patients who had unusual pruritic dermatitis associated with a specific clinical sign (comet sign) in 23 houses in southeastern France from May through September 2007. Pyemotes ventricosus, a parasite of the furniture beetle Anobium punctatum, was the cause of this condition. PMID:18976564

  12. Education in France: Number 41.

    ERIC Educational Resources Information Center

    French Embassy, New York, NY. French Cultural Services.

    The history and modernization of the French nursery and elementary schools are the focal points of this review of educational trends in France. One major section discussed the "Ecole Maternelle", kindergarten, nursery schools, the "Jardin d'Enfants", and new math. Another section treats: (1) "Les Ecoles Primaires", (2) village schools, (3) the…

  13. AirMSPI PODEX BigSur Terrain Images

    Atmospheric Science Data Center

    2013-12-13

    ... from the PODEX 2013 Campaign   Big Sur target (Big Sur, California) 02/03/2013 Terrain-projected   Select ...   Version number   For more information, see the Data Product Specifications (DPS)   ...

  14. [End of life in France].

    PubMed

    Vacheron, André

    2013-01-01

    Two major changes in end-of-life management have occured in recent decades: first, because of the increase in life expectancy and the resulting aging of the population, most deaths now involve old or very old people; second, more than two-thirds of deaths occur in a hospital or an institution. Our fellow citizens are afraid of suffering and death. They wish for a peaceful death, as rapid as possible and, in recent surveys, say they favour euthanasia. Yet euthanasia is illegal in France and in most other Western countries (with the exception of the Benelux nations). Palliative care ensures dignity in death, without anxiety of suffering, and is expanding rapidly in France. Léonetti's law of 22 April 2005 ensures the protection of the weakest, who should never be considered unworthy of life, yet is poorly known to the public and even to physicians. It now needs to be applied in practice. PMID:25518160

  15. "Franklin: Science, Politics and France"

    NASA Astrophysics Data System (ADS)

    McClellan, James E., III

    2003-04-01

    This presentation traces Benjamin Franklin's career as a "civic scientist" in Old-Regime France. It outlines the initial - and not always positive - reception of Franklin's work on electricity by the community of French scientists in the 1750s. It sketches Franklin's subsequent elevation into the pantheon of French Enlightenment heros, and it details his work as a "civic scientist" while American envoy to France in the 1770s and 1780s, notably his service on the government-sponsored commissions that repudiated the scientific and medical claims of Franz Anton Mesmer. This presentation concludes by examining a few features of Franklin's career that are not completely congruent with our notion of what a "civic scientist" might be, a contrast that is intended to illuminate both Franklin and the concept of "civic scientist."

  16. Macrofauna associated with temporary Sabellaria alveolata reefs on the west coast of Cotentin (France).

    PubMed

    Schlund, Erika; Basuyaux, Olivier; Lecornu, Billie; Pezy, Jean-Philippe; Baffreau, Alexandrine; Dauvin, Jean-Claude

    2016-01-01

    The polychaete Sabellaria alveolata (Linnaeus, 1767) is an important ecosystem engineer building reef structures which add to the topographic complexity in colonized areas. In Europe, the most extensive reef formation is located in the Bay of Mont-Saint-Michel (France). Since 2006, Sabellaria bio-constructions have developed on hard substrates along the west coast of the Cotentin Peninsula between Champeaux and Saint-Germain-sur-Ay on the northern part of the Bay of Mont-Saint-Michel. In this sector, two distinct types of bio-construction can be distinguished: platforms and reefs. The aim of this study is to analyse the patterns of the associated macrofauna on these platforms and reefs, as well as outside, and test for a correlation between the presence of Sabellaria bio-constructions and the richness of the benthic macrofauna. Univariate analyses are used to compare the macrofauna on four sites (Champeaux, Lingreville, Blainville-sur-Mer and Saint-Germain-sur-Ay). The results show a higher taxonomic richness on the platform-type than on the reef-type structures, and also a higher taxonomic richness outside the bio-construction areas. This suggests that, on the examined sites, the presence of S. alveolata bio-constructions does not contribute to higher levels of benthic macrofaunal richness on hard substrates. Temporary bio-constructions along this coast exhibit reefs of interest at some sites as well as in very small zones which merit special attention. PMID:27536543

  17. Macrofauna associated with temporary Sabellaria alveolata reefs on the west coast of Cotentin (France).

    PubMed

    Schlund, Erika; Basuyaux, Olivier; Lecornu, Billie; Pezy, Jean-Philippe; Baffreau, Alexandrine; Dauvin, Jean-Claude

    2016-01-01

    The polychaete Sabellaria alveolata (Linnaeus, 1767) is an important ecosystem engineer building reef structures which add to the topographic complexity in colonized areas. In Europe, the most extensive reef formation is located in the Bay of Mont-Saint-Michel (France). Since 2006, Sabellaria bio-constructions have developed on hard substrates along the west coast of the Cotentin Peninsula between Champeaux and Saint-Germain-sur-Ay on the northern part of the Bay of Mont-Saint-Michel. In this sector, two distinct types of bio-construction can be distinguished: platforms and reefs. The aim of this study is to analyse the patterns of the associated macrofauna on these platforms and reefs, as well as outside, and test for a correlation between the presence of Sabellaria bio-constructions and the richness of the benthic macrofauna. Univariate analyses are used to compare the macrofauna on four sites (Champeaux, Lingreville, Blainville-sur-Mer and Saint-Germain-sur-Ay). The results show a higher taxonomic richness on the platform-type than on the reef-type structures, and also a higher taxonomic richness outside the bio-construction areas. This suggests that, on the examined sites, the presence of S. alveolata bio-constructions does not contribute to higher levels of benthic macrofaunal richness on hard substrates. Temporary bio-constructions along this coast exhibit reefs of interest at some sites as well as in very small zones which merit special attention.

  18. [Health and politics in France].

    PubMed

    Tabuteau, Didier

    2012-06-01

    Health is a dual notion. It is individual, singular and intimate. It is also collective, statistical and political. The modern problematic of health relies upon a balance of complex relations between individual and collective acceptances of the notion. You can try to outline the evolutions and the main concepts through a quadruple approach: health and politics, health and its professionals, health and society and in the end, health and the State. The relationships between health and politics in France are affected by the historical delay of France in public health, namely because of a structural weakness of the administrative organization of public health. Nevertheless France developed a dense and well organized care system and a universal social protection against the disease. The creation of the health professions in France was marked by a historical opposition between the doctors and the state which led to a failure of hygienist medicine and a fundamental misunderstanding on health insurance. Medical domination led to the organization of a system based on professional dichotomy and the delegation of the regulation skills to the health care professionals. The role of health issues in the French society was deeply renewed by the development of the medical and epidemiological knowledge. This resulted in a new political responsibility in the management of health risks but also in the confirmation of the patients' rights and the role of their associations in the health systems operations and the piloting of public policies. In this environment, the state has recently and progressively confirmed its dominating role in the health sector. A public hospital service was created In the 60's and 70's, then in the 80's there were recurrent interventions in order to control health spendings and eventually in the 90's health safety devices were set up. More recently, a process of health policies institutionalization confirmed this evolution. In the future, health issues should

  19. Le sigle: apercu linguistique (The Acronym: A Linguistic Sketch)

    ERIC Educational Resources Information Center

    Gehenot, Daniel

    1975-01-01

    This article discusses the definition, classification, etymology and history, formation and the use of acronyms, and provides a list of the most common acronyms currently in use. (Text is in French.) (CLK)

  20. [Dengue fever in mainland France].

    PubMed

    Paty, M-C

    2014-11-01

    Dengue fever is the most widespread distributed vector borne viral disease. It is transmitted through the bites of Aedes aegypti and Aedes albopictus mosquitoes. With the expansion of Aedes albopictus and increasing travel exchange, it is no longer limited to the tropical zone and transmission has been documented in temperate areas. In mainland France, where Aedes albopictus has been present and disseminating since 2004, 2 episodes of autochthonous transmission occurred in 2010 and in 2013. Control measures against dengue and chikungunya, which shares the same vector, are implemented every year since 2006, in the areas where the vector is present. They aim at preventing or limiting local transmission of these diseases. They are based on epidemiological and entomological surveillance and vector control measures. The diagnosis of dengue, and chikungunya should be considered in case of suggestive symptoms in patients returning from an area of virus circulation. It should also be considered for patients living or having stayed in areas of mainland France where Aedes albopictus is present, during its activity period from May 1 to November 30. The prevention and control system, including vector control measures and the notification of cases to the local health authority should be known, as the risk of autochthonous transmission increases every year. PMID:25080833

  1. [Dengue fever in mainland France].

    PubMed

    Paty, M-C

    2014-11-01

    Dengue fever is the most widespread distributed vector borne viral disease. It is transmitted through the bites of Aedes aegypti and Aedes albopictus mosquitoes. With the expansion of Aedes albopictus and increasing travel exchange, it is no longer limited to the tropical zone and transmission has been documented in temperate areas. In mainland France, where Aedes albopictus has been present and disseminating since 2004, 2 episodes of autochthonous transmission occurred in 2010 and in 2013. Control measures against dengue and chikungunya, which shares the same vector, are implemented every year since 2006, in the areas where the vector is present. They aim at preventing or limiting local transmission of these diseases. They are based on epidemiological and entomological surveillance and vector control measures. The diagnosis of dengue, and chikungunya should be considered in case of suggestive symptoms in patients returning from an area of virus circulation. It should also be considered for patients living or having stayed in areas of mainland France where Aedes albopictus is present, during its activity period from May 1 to November 30. The prevention and control system, including vector control measures and the notification of cases to the local health authority should be known, as the risk of autochthonous transmission increases every year.

  2. Vocational Training of Young Migrants in France.

    ERIC Educational Resources Information Center

    Raimond, Jean-Marie

    This document reviews the literature on France's approximately 1.5 million young migrants. The introduction states that it is the second generation of migrants that were studied. In the second chapter, the statistical sources analyzed are explained and general descriptive statistics about foreigners in France are reported, including their numbers,…

  3. Apprenticeship in France: Between Tradition and Innovation.

    ERIC Educational Resources Information Center

    Simon-Zarca, Georgie

    1996-01-01

    A study was made of the state of apprenticeship in France, using data gathered through telephone interviews with apprentices. Of a targeted group of 6,000 young apprentices, 70% participated in the survey. The study found that, until recently, apprenticeships had generally been used in France to train students in manual trades. During the past 10…

  4. Regulation of Biobanks in France.

    PubMed

    Rial-Sebbag, Emmanuelle; Pigeon, Anna

    2015-01-01

    The privacy of biobank research participants in France is protected by a combination of bioethics laws, research laws, and data protection laws. Although the law has attempted to facilitate research by creating an opt-out regime for research with pre-existing samples, other aspects of the law hinder research. The requirement for multiple consents throughout the process of biobank sample collection and use, the lack of acceptance of a broad consent for biobanking, and genetic exceptionalism in the law all complicate biobank research. With IRB approval, opt-out consent may be used for genetic research using human tissue collected for other purposes, but express consent is still required for research with the associated genetic data. Among the important issues remaining to be addressed are harmonizing and simplifying the various informed consent processes.

  5. Late abortion meeting, Paris / France.

    PubMed

    Spinelli, A

    1989-01-01

    On January 27 and 28, 1989 a workshop and a meeting were organized in Paris by Mouvement Francais pour le Planning Familial (MFPF/France) and the IPPF Europe Region. The workshop was held on the first day. 24 staff and volunteers from Planned Parenthood Associations of 15 countries attended, reviewing abortion laws, the definition of therapeutic abortion, and the incidence and problems of second trimester abortion. Second trimester abortion is available in only a few European countries. Second trimester abortions are rare in France (about 2000 per annum), and in 1986 1717 French women travelled to England in order to seek an abortion. All late abortions are performed for serious reasons. Older women may mistake signs of pregnancy for the onset of the menopause; and women fearful of social or familial punishment, especially teenagers, may be reluctant to consult a doctor. The experiences of Denmark and Sweden, where the problem is partially solved, suggest some strategies: optimize accessibility of contraceptive services, particularly for women at higher risk of late abortion; diminish the taboo surrounding abortion, so that women are less frightened to seek help at an early stage of pregnancy; make abortion services available in all regions of the country; avert time-consuming enforced waiting periods or consent for minors; and stimulate public information campaigns on the importance of seeking help early. On January 28 a meeting involving about 200 participants took place at the Universite Paris Dauphine, Salle Raymond Aron. Speakers at the meeting discussed the issue of late abortion in Europe, the difficulties of obtaining late abortions, counseling, medical problems, the woman's point of view, and possible solutions. At the close of the meeting, the MFPF called on the French government to modify some of the articles in the Penal Code that restrict women's access to safe and legal abortion.

  6. Sur8 mediates tumorigenesis and metastasis in colorectal cancer

    PubMed Central

    Lee, Young-Mi; Kaduwal, Saluja; Lee, Kug Hwa; Park, Jong-Chan; Jeong, Woo-Jeong; Choi, Kang-Yell

    2016-01-01

    Sur8, a scaffold protein of the Ras pathway, interacts with Ras and Raf and modulates the Ras-extracellular signal-regulated kinase (ERK) pathway. Here we show that Sur8 is overexpressed in established human colorectal cancer (CRC) cell lines and CRC patient tissues. Moreover, Sur8 expression is increased during liver metastasis in CRC patients. Sur8 knockdown decreases ERK and Akt activities in CRC cell lines, regardless of their K-Ras, B-Raf or PI3K mutation status. Overexpression or knockdown of Sur8 increases or decreases, respectively, the proliferation or transformation of CRC cell lines. Sur8 knockdown attenuates the migration and invasion of HCT116 CRC cells. Subcutaneous or orthotopic injection of HCT116 cells harboring a doxycycline (Dox)-mediated Sur8 knockdown system in nude mice resulted in decreased tumorigenic potential and inhibited the liver metastatic potential of HCT116 cells. Taken together, our data support the role of Sur8 as a promoter of tumorigenesis and liver metastasis in CRC through its modulation of the Ras-ERK and PI3K-Akt signaling pathways. PMID:27469030

  7. Sur8 mediates tumorigenesis and metastasis in colorectal cancer.

    PubMed

    Lee, Young-Mi; Kaduwal, Saluja; Lee, Kug Hwa; Park, Jong-Chan; Jeong, Woo-Jeong; Choi, Kang-Yell

    2016-01-01

    Sur8, a scaffold protein of the Ras pathway, interacts with Ras and Raf and modulates the Ras-extracellular signal-regulated kinase (ERK) pathway. Here we show that Sur8 is overexpressed in established human colorectal cancer (CRC) cell lines and CRC patient tissues. Moreover, Sur8 expression is increased during liver metastasis in CRC patients. Sur8 knockdown decreases ERK and Akt activities in CRC cell lines, regardless of their K-Ras, B-Raf or PI3K mutation status. Overexpression or knockdown of Sur8 increases or decreases, respectively, the proliferation or transformation of CRC cell lines. Sur8 knockdown attenuates the migration and invasion of HCT116 CRC cells. Subcutaneous or orthotopic injection of HCT116 cells harboring a doxycycline (Dox)-mediated Sur8 knockdown system in nude mice resulted in decreased tumorigenic potential and inhibited the liver metastatic potential of HCT116 cells. Taken together, our data support the role of Sur8 as a promoter of tumorigenesis and liver metastasis in CRC through its modulation of the Ras-ERK and PI3K-Akt signaling pathways. PMID:27469030

  8. Adolescence et pornographie sur la toile

    PubMed Central

    Haza, Marion

    2012-01-01

    Dans cet article, nous abordons la question de l’accès à la pornographie sur Internet par les adolescents. Nous déclinons plusieurs facettes de ces rencontres: la rencontre «fortuite», quand les adolescents sont confrontés à des images intempestives, des publicités ou spams avec des contenus pornographiques; la rencontre «spectatrice», quand les adolescents cherchent activement des vidéos ou photos mettant en scène la sexualité; et enfin la rencontre «actrice», quand les adolescents se mettent en scène eux-mêmes, seuls ou à plusieurs, de façon pornographique sur le Net. A partir d’exemple, nous réfléchissons aux enjeux de ces rencontres virtuelles précoces de la sexualité adulte par rapport au développement adolescent et à la représentation de leur propre sexualité en construction. PMID:22876261

  9. [Cannabis in France, new insights].

    PubMed

    Costentin, Jean

    2014-03-01

    France holds the record for cannabis use in Europe, especially among adolescents. This drug of abuse is thus mainly used during a very sensitive period of brain development, education, vehicle driving and development of life projects. In addition, synthetic derivatives of tetrahydrocannabinol (THC), which are more noxious than cannabis itself are now appearing on the market. Traficking and cultivation for personnal use have intensified; products proposed for sale are richer in THC; and some methods of consumption (e-cigarettes, vaporizers, water pipes) increase the supply of THC to the lungs and thence to the body and brain. It is in this context that attempts are being made to legalize this drug of abuse. Other attempts are made to disguise it as a medication. Meanwhile, the list of its psychic as well as physical damages grows longer, with some very severe cases of major injuries. This evolution takes place in spite of numerous warnings expressed by the French Academy of Medicine. Subsequently, it is prompted to carefully and vigorously denounce these events. This will be the aim of this thematic session. PMID:26427294

  10. [Cannabis in France, new insights].

    PubMed

    Costentin, Jean

    2014-03-01

    France holds the record for cannabis use in Europe, especially among adolescents. This drug of abuse is thus mainly used during a very sensitive period of brain development, education, vehicle driving and development of life projects. In addition, synthetic derivatives of tetrahydrocannabinol (THC), which are more noxious than cannabis itself are now appearing on the market. Traficking and cultivation for personnal use have intensified; products proposed for sale are richer in THC; and some methods of consumption (e-cigarettes, vaporizers, water pipes) increase the supply of THC to the lungs and thence to the body and brain. It is in this context that attempts are being made to legalize this drug of abuse. Other attempts are made to disguise it as a medication. Meanwhile, the list of its psychic as well as physical damages grows longer, with some very severe cases of major injuries. This evolution takes place in spite of numerous warnings expressed by the French Academy of Medicine. Subsequently, it is prompted to carefully and vigorously denounce these events. This will be the aim of this thematic session.

  11. 75 FR 16839 - Sorbitol From France

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-02

    ..., 2009, the Commission established a schedule for the conduct of the review (74 FR 66992, December 17... From the Federal Register Online via the Government Publishing Office INTERNATIONAL TRADE COMMISSION Sorbitol From France AGENCY: United States International Trade Commission. ACTION:...

  12. Demoiselles and Drafts from Italy and France.

    ERIC Educational Resources Information Center

    Picard, M. Dane

    1988-01-01

    Recounts the adventures of a journey taken through France and Italy. Makes an analogy of this trip to that of the one Charles Dickens took in 1844. Describes silicified horizons of the southern Paris Basin, moraines, outcrops, and "Hoodoos." (RT)

  13. Lithiase géante sur enterocystoplastie

    PubMed Central

    Elmortaji, Khalid; Elomri, Ghassane; Bennani, Saad; Rabii, Redouane; Aboutaib, Rachid; Meziane, Fethi

    2014-01-01

    La formation des lithiases est une complication fréquente des entérocystoplasties après cystectomie radicale pour tumeur de vessie infiltrante. Le délai d'apparition dépend des facteurs de risque favorisants notamment les infections urinaires. Néanmoins la survenue de lithiase géante sur néovessie reste exceptionnelle, seulement 5 cas ont été rapportés dans la littérature. Nous rapportons dans ce travail, le cas d'une lithiase géante compliquant une entérocystoplastie chez un malade suivi pour tumeur de vessie infiltrante. PMID:25932070

  14. Advanced MCT technologies in France

    NASA Astrophysics Data System (ADS)

    Destefanis, Gérard; Tribolet, Philippe

    2007-04-01

    In this paper we present an overview of the very recent developments of the HgCdTe infrared detector technology developed by CEA-LETI and industrialized by Sofradir in France. Today Sofradir uses in production for more than 15years a very mature, reproducible, well mastered and fully understood, planar n on p ion implanted technology. This process that allows very high yields to be achieved in all infrared bands from SWIR to LWIR uses the very conventional approach of LPE growth of MCT on lattice-matched CdZnTe substrates. Progress in this field is continuous from 20years and has recently leaded to the fabrication of high performance VLWIR FPA (320x256 with cut off wavelengths as high as 20μm). Moreover, thanks to the design of the epitaxial structure and to the substrate removal step MCT FPAs present the unique features to have very high quantum efficiency (above 70%) from the cut off wavelength down to the UV. This effect, which opens new application fields, was recently demonstrated in SWIR 320x256 FPAs with cut off wavelength of 2.5μm. Very high quality FPAs (1280x1024) with pitches as small as 15μm have already been demonstrated last year using the MBE growth of MWIR MCT epilayers on 4 inches germanium substrates, n on p ion implanted photodiodes and the hot welding indium bump hybridization technique. At the same time, with the MBE growth, bicolor and dual band FPAs which uses more complex multi hetero-junctions architectures (both 4 layers npn and 'pseudo planar' structures and extrinsically doped MCT layers) were fabricated with formats of 320x256 and pitches as small as 25μm. A very new area of development concerns avalanche photodiodes (APD) made with MCT. This semiconductor presents a unique feature among all the over semiconductors. Extremely high avalanche gains can be obtained on n on p photodiodes without absolutely any noise excess (F(K)=1): MCT APDs act as perfect amplifiers. These results open new interesting fields of investigation for low

  15. Evaluation d'impact sur la santé et évaluation d'impact sur l'équité en santé : éventail de pratiques et questions de recherche.

    PubMed

    Villeval, Mélanie; Bidault, Elsa; Lang, Thierry

    2016-09-01

    L'Evaluation d'Impact sur la Santé (EIS) se développe au niveau international et est encore au stade émergent en France. Elle vise à évaluer les effets positifs et négatifs potentiels d'un projet, d'un programme ou d'une politique sur la santé. L'objectif est de produire des recommandations en direction des décideurs, afin d'en maximiser les effets positifs et d'en diminuer les effets négatifs. L'EIS est un moyen particulièrement intéressant d'action sur les déterminants de la santé au-delà des comportements individuels et du système de santé. Les politiques de logement, de transport, de solidarité, économiques, etc. ont, en effet, des impacts souvent non prévus sur la santé. Au-delà des effets sur la santé, l'EIS doit aussi permettre d'apprécier la distribution de ces effets dans la population.Si la préoccupation pour l'équité en santé est centrale dans l'EIS, elle reste cependant difficilement traduite en pratique. Face à cette difficulté, des démarches d'évaluation d'impact ont été développées pour renforcer la prise en compte de l'équité à chaque étape de l'EIS ou « Equity Focused Health Impact Assessment », ou prendre en compte les impacts sur les inégalités de santé de façon spécifique. Ainsi, l'Evaluation de l'Impact sur l'Equité en Santé (EIES) semble, par exemple, particulièrement intéressante pour évaluer l'impact sur les inégalités de projets dans le champ sanitaire.L'EIS et l'EIES posent de nombreuses questions de recherche, notamment autour de la réunion, dans une même démarche, du politique, du citoyen et de l'expert. La participation des populations vulnérables potentiellement affectées par la politique évaluée est une valeur centrale de l'EIS, mais pose des questions d'acceptabilité sociale. La collaboration avec les décideurs politiques est également un enjeu majeur. Les difficultés méthodologiques, notamment de quantification des impacts, peuvent constituer des freins à la promotion

  16. Evaluation d'impact sur la santé et évaluation d'impact sur l'équité en santé : éventail de pratiques et questions de recherche.

    PubMed

    Villeval, Mélanie; Bidault, Elsa; Lang, Thierry

    2016-09-01

    L'Evaluation d'Impact sur la Santé (EIS) se développe au niveau international et est encore au stade émergent en France. Elle vise à évaluer les effets positifs et négatifs potentiels d'un projet, d'un programme ou d'une politique sur la santé. L'objectif est de produire des recommandations en direction des décideurs, afin d'en maximiser les effets positifs et d'en diminuer les effets négatifs. L'EIS est un moyen particulièrement intéressant d'action sur les déterminants de la santé au-delà des comportements individuels et du système de santé. Les politiques de logement, de transport, de solidarité, économiques, etc. ont, en effet, des impacts souvent non prévus sur la santé. Au-delà des effets sur la santé, l'EIS doit aussi permettre d'apprécier la distribution de ces effets dans la population.Si la préoccupation pour l'équité en santé est centrale dans l'EIS, elle reste cependant difficilement traduite en pratique. Face à cette difficulté, des démarches d'évaluation d'impact ont été développées pour renforcer la prise en compte de l'équité à chaque étape de l'EIS ou « Equity Focused Health Impact Assessment », ou prendre en compte les impacts sur les inégalités de santé de façon spécifique. Ainsi, l'Evaluation de l'Impact sur l'Equité en Santé (EIES) semble, par exemple, particulièrement intéressante pour évaluer l'impact sur les inégalités de projets dans le champ sanitaire.L'EIS et l'EIES posent de nombreuses questions de recherche, notamment autour de la réunion, dans une même démarche, du politique, du citoyen et de l'expert. La participation des populations vulnérables potentiellement affectées par la politique évaluée est une valeur centrale de l'EIS, mais pose des questions d'acceptabilité sociale. La collaboration avec les décideurs politiques est également un enjeu majeur. Les difficultés méthodologiques, notamment de quantification des impacts, peuvent constituer des freins à la promotion

  17. [Epidemiology of tuberculosis in France in 2005].

    PubMed

    Antoine, D; Che, D

    2007-05-01

    This article presents results on cases of tuberculosis disease notified in France in 2005 by mandatory notification. In 2005, a total of 5,374 cases were notified in France, representing a rate of 8.9 cases per 100,000. The notification rate per 100,000 was below 10 in all French regions, except the Ile-de-France and French Guyana (with respective rates of 19.7/10(5) and 44.0/10(5)). Notification rates were higher in some population groups such as people born abroad (41.5/10(5)), especially those born in sub-Saharan Africa (160/10(5)), and those recently (<2 years) arrived in France (251/10(5)), in homeless people (214/10(5)), and in persons aged 80 years and over (21.7/10(5)). Pulmonary tuberculosis accounted for 73% of notified cases, 79% of which were contagious (positive direct examination of sputum, positive culture). Results from the notification of tuberculosis disease in 2005 indicate a continuing decrease of incidence in France. However, the high incidence in some population groups requires adapting public health actions to the needs of population groups more exposed to tuberculosis.

  18. [Epidemiology of tuberculosis in France in 2008].

    PubMed

    Che, D; Antoine, D

    2011-07-01

    A total of 5,758 tuberculosis cases were notified in France in 2008, giving a rate of nine cases per 100,000 inhabitants. The median age was 45 years and 59% of cases were male patients. Île-de-France (Paris and greater Paris area) and French Guiana had the highest notification rate in 2008 (17.9/10(5) and 22.6/10(5) respectively). The rate of tuberculosis was higher in individuals born abroad (43.2/10(5) vs. 5.0/10(5) for individuals born in France), especially those recently arrived in France. Pulmonary tuberculosis accounted for 72% of notified cases, 76% of which were potentially contagious (positive sputum smear, or culture). Compared to 2007, the number of notified tuberculosis cases increased by 3.3% in 2008. This increase was not accompanied by a rise of severe cases (meningitis and miliary TB); this seemed to be due partly to improvement in identification and notification of cases. However this trend could require specific monitoring in future years. A national tuberculosis control program was launched in France in 2007, aiming at reducing epidemiological disparities. Clinical and public health expertise needs to be maintained on all the territory to ensure that implemented measures can have the expected impact on the epidemiology of the disease.

  19. AirMSPI PODEX Big Sur Ellipsoid Images

    Atmospheric Science Data Center

    2013-12-11

    ... AirMSPI Browse Images from the PODEX 2013 Campaign   Big Sur target 02/03/2013 Ellipsoid-projected   Select ...   Version number   For more information, see the  Data Product Specifications (DPS) ...

  20. The International Heliophysical Year in France

    NASA Astrophysics Data System (ADS)

    Schmieder, B.

    We are preparing in France the anniversary of IGY 50 We are gathering our efforts around few actions 1 We planned to follow the international campaigns with our solar Telescope THEMIS in Tenerife with the spacecrafts SOHO Cluster and the magnetometers of Superdarn A group is already formed with C Hanuise as responsible to understand some physical processes involved in these phenomena by using former data 2 On the initiative of CAWSES SCOSTEP program we plan to rehabilitate our heliograph in Meudon in order to be able to participate to the international network of flare survey The Japonese are leading this program Shibata and Kurokawa 3 We are developping lectures for students in different places in France We planned to work on the development of a DVD and video games in a IHY European context 4 We have also an outreach program which consists of an exhibition This exibition could be duplicated in France and for French speaking countries

  1. [Utilization of methylphenidate(Ritalin) in France].

    PubMed

    Frances, C; Hoizey, G; Millart, H; Trenque, T

    2002-01-01

    Methylphenidate (Ritalin) is the only psychostimulant approved in France and indicated in attention deficit hyperactivity disorder in children over 6 years. It is under restricted prescription and distribution conditions. As such, it requires a hospital initiated prescription from either a neurology, psychiatry or pediatric specialist and it is covered by the "narcotics" schedule. The French Pharmacovigilance database spontaneous adverse drug reactions reporting, since it was approved in 1995, were analyzed. 21 adverse drug reactions were reported. In 16 cases, methylphenidate was suspected. They were generally non-serious, mild side effects and in most cases promptly resolved. These results do not suggest methylphenidate misuse in France or an overuse in between 1300 and 4000 treated children, to date. Until more information is available concerning the long-term effects of methylphenidate, and in order to limit misuse, inappropriate or overuse, the current prescription and dispensing regulation should be maintained in France, and could well be developed in other countries.

  2. Lignes directrices canadiennes sur la rhinosinusite chronique

    PubMed Central

    Kaplan, Alan

    2013-01-01

    Résumé Objectif Présenter un résumé clinique des lignes directrices canadiennes sur la rhinosinusite chronique (RSC) qui comporte des recommandations pertinentes aux médecins de famille. Qualité des données Les auteurs des lignes directrices ont effectué une recherche documentaire systématique dans la littérature médicale et ont rédigé une ébauche de recommandations. Une cote a été donnée à la fois en fonction de la fiabilité des données probantes et de la solidité des recommandations. On a sollicité les commentaires d’experts en contenu de l’extérieur, ainsi que l’aval des sociétés médicales (Association pour la microbiologie médicale et l’infectiologie Canada, Société canadienne d’allergie et d’immunologie clinique, Canadian Society of Otolaryngology—Head and Neck Surgery, Association canadienne des médecins d’urgence et Regroupement canadien des médecins de famille en santé respiratoire). Message principal Le diagnostic d’une RSC se fonde sur le type et la durée des symptômes et une constatation objective d’une inflammation de la muqueuse nasale ou des sinus paranasaux. La rhinosinusite chronique est catégorisée en fonction de la présence ou de l’absence de polypes nasaux et cette distinction entraîne des différences dans le traitement. On traite la rhinosinusite chronique avec polypes nasaux au moyen de corticostéroïdes par voie intranasale. Des antibiotiques sont recommandés quand les symptômes indiquent une infection (douleur ou purulence). Pour une RSC sans polypes nasaux, on recommande des corticostéroïdes par voie intranasale et des antibiotiques de deuxième ligne (par ex. combinaisons amoxicilline–acide clavulanique ou fluoroquinolones à activité accrue contre Gram positif). Une irrigation avec une solution saline, des stéroïdes par voie orale et des tests d’allergies pourraient être appropriées. Si le patient ne répond pas au traitement, il faudrait envisager d

  3. Syphilis surveillance in France, 2000-2003.

    PubMed

    Couturier, E; Michel, A; Janier, M; Dupin, N; Semaille, C

    2004-12-01

    This article describes syphilis trends, characteristics of patients from 2000 to 2003 in France and trends of the benzylpenicillin benzathine 2.4 million UI sales from 2001 to 2003. The ongoing surveillance system for syphilis case reporting since 2001 has been set up in volunteer settings, mostly public settings where STI treatment is offered. Clinical case reporting is complemented by sexual behavioural data based on a self-administered questionnaire. From 2000 to 2003, 1089 syphilis cases were reported in France, increasing from 37 cases in 2000 to 428 in 2003. Overall, 96% of syphilis cases were in men with a mean age of 36.5 years and 70% of whom were born in France. The proportion of syphilis cases with HIV co-infection decreased over time from 60% in 2000 to 33% in 2003. The most affected area by the syphilis epidemic is the Ile-de-France region, mainly the city of Paris. The greatest proportion of syphilis cases diagnosed in men who have sex with men (MSM) were in the Ile-de-France region, where they made up 87% of cases, compared with 75% in other regions. Among the patients who completed the self-administered questionnaire on sexual behaviour, 83% reported having casual sex partners in the 3 months prior to their syphilis diagnosis. Trends in the sales of benzylpenicillin benzathine 2.4 million UI in private pharmacies are similar to those observed in the surveillance system, and increased between 2001 and 2003. In conclusion, syphilis transmission is still ongoing in France in 2003 and the role of unprotected oral sex in the transmission of syphilis should be emphasised. PMID:15677855

  4. 75 FR 39277 - Sorbitol From France; Determination

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-08

    ... The Commission instituted this review on July 1, 2009 (74 FR 31762, July 2, 2009) and determined on... publishing the notice in the Federal Register on December 17, 2009 (74 FR 66992). The hearing was held in... COMMISSION Sorbitol From France; Determination On the basis of the record \\1\\ developed in the subject...

  5. Murine Typhus, Reunion, France, 2011–2013

    PubMed Central

    Camuset, Guillaume; Socolovschi, Cristina; Moiton, Marie-Pierre; Kuli, Barbara; Foucher, Aurélie; Poubeau, Patrice; Borgherini, Gianandrea; Wartel, Guillaume; Audin, Héla; Raoult, Didier; Filleul, Laurent; Parola, Philippe; Pagès, Fréderic

    2015-01-01

    Murine typhus case was initially identified in Reunion, France, in 2012 in a tourist. Our investigation confirmed 8 autochthonous cases that occurred during January 2011–January 2013 in Reunion. Murine typhus should be considered in local patients and in travelers returning from Reunion who have fevers of unknown origin. PMID:25625653

  6. Frances Rauscher: Music and Reasoning. Interview.

    ERIC Educational Resources Information Center

    Snyder, Neal

    1995-01-01

    Reports on an interview with Frances Rauscher, a research psychologist and musician who has studied the effects of music on the brain. Maintains that students who have studied music have enhanced spatial reasoning. Recommends that music education begin at younger ages. (CFR)

  7. The Occitan Movement in Southern France.

    ERIC Educational Resources Information Center

    Engelhardt, Klaus

    The Occitan movement in Southern France should be studied in the light of a world-wide political reality of our days, the surfacing of ethnic minorities which are beginning to voice cultural and political demands in almost all large industrialized or developing countries. The first step for a minority group to come into existence is almost without…

  8. [New conditions for organ donation in France].

    PubMed

    Antoine, Corinne; Maroudy, Daniel

    2016-09-01

    The procurement of organs from donors after circulatory death is a reliable technique which gives satisfactory posttransplant results and also represents a potential source of additional organs. In order to meet the growing need for organ donations, the 'anticipated organ donation approach' procedure is currently receiving renewed interest with new conditions for its implementation in France. PMID:27596496

  9. Shocks and Aftershocks: France Confronts Its Past.

    ERIC Educational Resources Information Center

    Bracher, Nathan; Golsan, Richard

    1995-01-01

    Maintains that events in France during and after World War II are still controversial political and social issues. Describes the program and activities of U.S. teachers during a summer seminar on French literature and filmmaking during the German occupation years. (CFR)

  10. Competence: Conceptual Approach and Practice in France

    ERIC Educational Resources Information Center

    Le Deist, Francoise

    2009-01-01

    Purpose: The purpose of this article is to analyse the conceptual approaches to competence and practice in competence management in France. Design/methodology/approach: Extensive literature review, discussion with academic experts in the French competence network of AGRH and interviews concerning developments following the 2003 national agreement…

  11. A Paradox in Physics Education in France

    ERIC Educational Resources Information Center

    Smigiel, Eddie; Sonntag, Michel

    2013-01-01

    This paper deals with the nature and the level of difficulty of teaching and learning physics in the first year of undergraduate engineering schools in France. Our case study is based on a survey regarding a classic and basic question in applied physics, and which was conducted with a group of second-year students in a post-baccalaureate 1…

  12. Les instituts universitaires de technologie en France. (The university institutes of technology in France)

    ERIC Educational Resources Information Center

    Pineau, Gaston

    1971-01-01

    In 1966 France passed legislation naming three types of technical training: two year postbaccalaureate, short-cycle for those without a bachelor's degree, adult education, for those already employed. (MF)

  13. Aging in France: Population Trends, Policy Issues, and Research Institutions

    ERIC Educational Resources Information Center

    Beland, Daniel; Durandal, Jean-Philippe Viriot

    2013-01-01

    Like in other advanced industrial countries, in France, demographic aging has become a widely debated research and policy topic. This article offers a brief overview of major aging-related trends in France. The article describes France's demographics of aging, explores key policy matters, maps the institutional field of French social gerontology…

  14. Fires Burning near Big Sur, California

    NASA Technical Reports Server (NTRS)

    2008-01-01

    Fires near Big Sur, Calif., continued to burn unchecked when the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) instrument on NASA's Terra satellite captured this image on Sunday, June 29. In Northern California alone, fires have consumed more than 346,000 acres.At least 18,000 people have deployed to attempt to extinguish or control the flames. Air quality as far away as San Francisco has been adversely impacted by the dense clouds of smoke and ash blowing towards the northwest. The satellite image combines a natural color portrayal of the landscape with thermal infrared data showing the active burning areas in red. The dark area in the lower right is a previous forest fire.

    ASTER is one of five Earth-observing instruments launched December 18, 1999, on NASA's Terra satellite. The instrument was built by Japan's Ministry of Economy, Trade and Industry. A joint U.S./Japan science team is responsible for validation and calibration of the instrument and the data products.

    The broad spectral coverage and high spectral resolution of ASTER provides scientists in numerous disciplines with critical information for surface mapping, and monitoring of dynamic conditions and temporal change. Example applications are: monitoring glacial advances and retreats; monitoring potentially active volcanoes; identifying crop stress; determining cloud morphology and physical properties; wetlands evaluation; thermal pollution monitoring; coral reef degradation; surface temperature mapping of soils and geology; and measuring surface heat balance.

    The U.S. science team is located at NASA's Jet Propulsion Laboratory, Pasadena, Calif. The Terra mission is part of NASA's Science Mission Directorate.

    Size: 35.4 by 57 kilometers (21.9 by 34.2 miles) Location: 36.1 degrees North latitude, 121.6 degrees West longitude Orientation: North at top Image Data: ASTER bands 3, 2, and 1 Original Data Resolution: 15 meters (49 feet) Dates Acquired: June 29

  15. Kir6.2 activation by sulfonylurea receptors: a different mechanism of action for SUR1 and SUR2A subunits via the same residues

    PubMed Central

    Principalli, Maria A; Dupuis, Julien P; Moreau, Christophe J; Vivaudou, Michel; Revilloud, Jean

    2015-01-01

    ATP-sensitive potassium channels (K-ATP channels) play a key role in adjusting the membrane potential to the metabolic state of cells. They result from the unique combination of two proteins: the sulfonylurea receptor (SUR), an ATP-binding cassette (ABC) protein, and the inward rectifier K+ channel Kir6.2. Both subunits associate to form a heterooctamer (4 SUR/4 Kir6.2). SUR modulates channel gating in response to the binding of nucleotides or drugs and Kir6.2 conducts potassium ions. The activity of K-ATP channels varies with their localization. In pancreatic β-cells, SUR1/Kir6.2 channels are partly active at rest while in cardiomyocytes SUR2A/Kir6.2 channels are mostly closed. This divergence of function could be related to differences in the interaction of SUR1 and SUR2A with Kir6.2. Three residues (E1305, I1310, L1313) located in the linker region between transmembrane domain 2 and nucleotide-binding domain 2 of SUR2A were previously found to be involved in the activation pathway linking binding of openers onto SUR2A and channel opening. To determine the role of the equivalent residues in the SUR1 isoform, we designed chimeras between SUR1 and the ABC transporter multidrug resistance-associated protein 1 (MRP1), and used patch clamp recordings on Xenopus oocytes to assess the functionality of SUR1/MRP1 chimeric K-ATP channels. Our results reveal that the same residues in SUR1 and SUR2A are involved in the functional association with Kir6.2, but they display unexpected side-chain specificities which could account for the contrasted properties of pancreatic and cardiac K-ATP channels. PMID:26416970

  16. Random assembly of SUR subunits in K(ATP) channel complexes.

    PubMed

    Cheng, Wayland W L; Tong, Ailing; Flagg, Thomas P; Nichols, Colin G

    2008-01-01

    Sulfonylurea receptors (SURs) associate with Kir6.x subunits to form tetradimeric K(ATP) channel complexes. SUR1 and SUR2 confer differential channel sensitivities to nucleotides and pharmacological agents, and are expressed in specific, but overlapping, tissues. This raises the question of whether these different SUR subtypes can assemble in the same channel complex and generate channels with hybrid properties. To test this, we engineered dimeric constructs of wild type or N160D mutant Kir6.2 fused to SUR1 or SUR2A. Dimeric fusions formed functional, ATP-sensitive, channels. Coexpression of weakly rectifying SUR1-Kir6.2 (WTF-1) with strongly rectifying SUR1-Kir6.2[N160D] (NDF-1) in COSm6 cells results in mixed subunit complexes that exhibit unique rectification properties. Coexpression of NDF-1 and SUR2A-Kir6.2 (WTF-2) results in similar complex rectification, reflecting the presence of SUR1- and SUR2A-containing dimers in the same channel. The data demonstrate clearly that SUR1 and SUR2A subunits associate randomly, and suggest that heteromeric channels will occur in native tissues. PMID:18690055

  17. Young people's heroes in France and Spain.

    PubMed

    Gash, Hugh; Domínguez Rodríguez, Pilar

    2009-05-01

    Heroes play collectivist or individualist roles in imagination and self-development. Representations of heroic figures in questionnaires given to French (n = 241) and Spanish (n = 227) samples of 10 and 15-year-olds were examined to assess the extent that heroes originated in digital media, and whether they were proximal or distal personalities. There is strong evidence that heroes in this sample were largely learned about in digital media (France 45%, Spain 50%): family and community heroes were a minority (France 11%, Spain 9%). Male heroes were more important to Spanish participants compared to their French peers. The acquisition sequence for hero type reported in the pre-television era, proximal (family and community) to distal (beyond the neighbourhood), is reversed in this study. Generally, 10-year-olds preferred heroes with collectivist qualities and 15-year-olds with individualised qualities. Findings are discussed in terms of the emergence of social capital. PMID:19476237

  18. Postglacial dispersal of Phlebotomus perniciosus into France.

    PubMed

    Perrotey, S; Mahamdallie, S S; Pesson, B; Richardson, K J; Gállego, M; Ready, P D

    2005-12-01

    Phlebotomus perniciosus was identified morphologically in samples from France and northeast Spain, and individuals were then characterized at three polymorphic isoenzyme loci (by isoelectrofocusing) and at the mitochondrial DNA locus (by comparative DNA sequence analysis of a fragment of the Cytochrome b gene). The four polymorphic loci gave conflicting patterns of population relationships, which can be explained by hypothesizing different amounts of gene introgression at each locus when two distinctive lineages met in southern France or northeast Spain after isolation in southern Italy and Spain during the Pleistocene Ice Ages. P. perniciosus is an important vector of leishmania infantum and so these population differentiation studies are relevant for predicting the emergence and spread of leishmaniasis in relation to environmental changes, including climate.

  19. Young people's heroes in France and Spain.

    PubMed

    Gash, Hugh; Domínguez Rodríguez, Pilar

    2009-05-01

    Heroes play collectivist or individualist roles in imagination and self-development. Representations of heroic figures in questionnaires given to French (n = 241) and Spanish (n = 227) samples of 10 and 15-year-olds were examined to assess the extent that heroes originated in digital media, and whether they were proximal or distal personalities. There is strong evidence that heroes in this sample were largely learned about in digital media (France 45%, Spain 50%): family and community heroes were a minority (France 11%, Spain 9%). Male heroes were more important to Spanish participants compared to their French peers. The acquisition sequence for hero type reported in the pre-television era, proximal (family and community) to distal (beyond the neighbourhood), is reversed in this study. Generally, 10-year-olds preferred heroes with collectivist qualities and 15-year-olds with individualised qualities. Findings are discussed in terms of the emergence of social capital.

  20. Minimally Invasive Forefoot Surgery in France.

    PubMed

    Meusnier, Tristan; Mukish, Prikesht

    2016-06-01

    Study groups have been formed in France to advance the use of minimally invasive surgery. These techniques are becoming more frequently used and the technique nuances are continuing to evolve. The objective of this article was to advance the awareness of the current trends in minimally invasive surgery for common diseases of the forefoot. The percutaneous surgery at the forefoot is less developed at this time, but also will be discussed.

  1. Enterovirus Migration Patterns between France and Tunisia

    PubMed Central

    Othman, Ines; Mirand, Audrey; Slama, Ichrak; Mastouri, Maha; Peigue-Lafeuille, Hélène; Aouni, Mahjoub; Bailly, Jean-Luc

    2015-01-01

    The enterovirus (EV) types echovirus (E-) 5, E-9, and E-18, and coxsackievirus (CV-) A9 are infrequently reported in human diseases and their epidemiologic features are poorly defined. Virus transmission patterns between countries have been estimated with phylogenetic data derived from the 1D/VP1 and 3CD gene sequences of a sample of 74 strains obtained in France (2000–2012) and Tunisia (2011–2013) and from the publicly available sequences. The EV types (E-5, E-9, and E-18) exhibited a lower worldwide genetic diversity (respective number of genogroups: 4, 5, and 3) in comparison to CV-A9 (n = 10). The phylogenetic trees estimated with both 1D/VP1 and 3CD sequence data showed variations in the number of co-circulating lineages over the last 20 years among the four EV types. Despite the low number of genogroups in E-18, the virus exhibited the highest number of recombinant 3CD lineages (n = 10) versus 4 (E-5) to 8 (E-9). The phylogenies provided evidence of multiple transportation events between France and Tunisia involving E-5, E-9, E-18, and CV-A9 strains. Virus spread events between France and 17 other countries in five continents had high probabilities of occurrence as those between Tunisia and two European countries other than France. All transportation events were supported by BF values > 10. Inferring the source of virus transmission from phylogenetic data may provide insights into the patterns of sporadic and epidemic diseases caused by EVs. PMID:26709514

  2. First case of human gongylonemosis in France.

    PubMed

    Pesson, Bernard; Hersant, Christel; Biehler, Jean-François; Abou-Bacar, Ahmed; Brunet, Julie; Pfaff, Alexander W; Ferté, Hubert; Candolfi, Ermanno

    2013-01-01

    Gongylonema spp. are cosmopolitan spirurid nematodes that are common parasites of wild and domesticated mammals and birds. Gongylonema pulchrum Molin, 1857 is most common in ruminants, where it invades mucosa and submucosa of the mouth, tongue, oesophagus and forestomachs. It extremely rarely occurs in man, and fewer than 60 cases have been reported worldwide. We report a case from the Alsace region, which appears to be the first case of human gongylonemosis described in France.

  3. First case of human gongylonemosis in France

    PubMed Central

    Pesson, Bernard; Hersant, Christel; Biehler, Jean-François; Abou-Bacar, Ahmed; Brunet, Julie; Pfaff, Alexander W.; Ferté, Hubert; Candolfi, Ermanno

    2013-01-01

    Gongylonema spp. are cosmopolitan spirurid nematodes that are common parasites of wild and domesticated mammals and birds. Gongylonema pulchrum Molin, 1857 is most common in ruminants, where it invades mucosa and submucosa of the mouth, tongue, oesophagus and forestomachs. It extremely rarely occurs in man, and fewer than 60 cases have been reported worldwide. We report a case from the Alsace region, which appears to be the first case of human gongylonemosis described in France. PMID:23425508

  4. The e-Bug project in France.

    PubMed

    Touboul, Pia; Dunais, Brigitte; Urcun, Jeanne-Marie; Michard, Jean-Louis; Loarer, Christian; Azanowsky, Jean-Michel; Vincent, Isabelle; Jestin, Christine; Housseau, Bruno; de Warren, Anne; Dellamonica, Pierre

    2011-06-01

    The high rates of antibiotic prescriptions and antimicrobial resistance in France motivated its participation in the European e-Bug school project concerning microbes, and infection transmission, prevention and treatment. The prospect of raising awareness among children, helping them to adopt suitable attitudes and behaviour towards infection transmission and treatment starting from childhood, generated enthusiastic support from relevant national educational and health institutions throughout the Project. France was actively involved in every stage: background research showed that the subject matter was best suited to the national science curricula of the fourth and fifth forms in junior schools, and the sixth and ninth forms in senior schools; a focus group study with junior and senior teachers elicited teachers' needs concerning teaching resources; and a qualitative and quantitative evaluation, after translation and pack review, enabled further adaptation of the packs. This evaluation showed an overall enthusiastic reception by teachers and their students in France, and reassured teachers on the ease of use of the Project's resources and students' progress. The e-Bug Project was launched through a national institutional implementation plan in September 2009 and orders for e-Bug tools increased rapidly. By the end of October, 57% of all senior science teachers and 16% of all junior school teachers had ordered the pack. France is one of the most frequent users of the e-Bug web site. The collaboration with both educational and health partners was particularly helpful to implementing the Project, and this was confirmed by the favourable reception and participation of teachers and students in the field.

  5. Enterovirus Migration Patterns between France and Tunisia.

    PubMed

    Othman, Ines; Mirand, Audrey; Slama, Ichrak; Mastouri, Maha; Peigue-Lafeuille, Hélène; Aouni, Mahjoub; Bailly, Jean-Luc

    2015-01-01

    The enterovirus (EV) types echovirus (E-) 5, E-9, and E-18, and coxsackievirus (CV-) A9 are infrequently reported in human diseases and their epidemiologic features are poorly defined. Virus transmission patterns between countries have been estimated with phylogenetic data derived from the 1D/VP1 and 3CD gene sequences of a sample of 74 strains obtained in France (2000-2012) and Tunisia (2011-2013) and from the publicly available sequences. The EV types (E-5, E-9, and E-18) exhibited a lower worldwide genetic diversity (respective number of genogroups: 4, 5, and 3) in comparison to CV-A9 (n = 10). The phylogenetic trees estimated with both 1D/VP1 and 3CD sequence data showed variations in the number of co-circulating lineages over the last 20 years among the four EV types. Despite the low number of genogroups in E-18, the virus exhibited the highest number of recombinant 3CD lineages (n = 10) versus 4 (E-5) to 8 (E-9). The phylogenies provided evidence of multiple transportation events between France and Tunisia involving E-5, E-9, E-18, and CV-A9 strains. Virus spread events between France and 17 other countries in five continents had high probabilities of occurrence as those between Tunisia and two European countries other than France. All transportation events were supported by BF values > 10. Inferring the source of virus transmission from phylogenetic data may provide insights into the patterns of sporadic and epidemic diseases caused by EVs.

  6. Cancer mortality among Polish migrants to France.

    PubMed

    Tyczynski, J; Parkin, D; Zatonski, W; Tarkowski, W

    1992-01-01

    Cancer risk in the Polish-born population of France has been compared to that in Poland and in native French subjects (born in France), using mortality data from the period 1979-1985. The Polish-born community in France is a long-established one--most migration occurred during the 1920s--so that for many cancer sites the cancer pattern is closer to that of French natives than that in Poland (eg oral cavity, oesophagus, large bowel, gall bladder, uterus, leukaemia). Polish migrants, however, retain their characteristically high rates of cancer of the stomach and lung (in men), and low rates of breast and prostate cancer. The Polish-born community has a characteristic pattern of residence (living mainly in the Nord and the Pas-de-Calais) and occupational status (a higher proportion of 'workers' than the French-born); these are important confounding factors which can mask the true differences in risk for several sites (larynx, oesophagus, large bowel) if no adjustment is made during analysis. PMID:1467602

  7. Populations at Risk for Alveolar Echinococcosis, France

    PubMed Central

    Piarroux, Martine; Piarroux, Renaud; Knapp, Jenny; Bardonnet, Karine; Dumortier, Jérôme; Watelet, Jérôme; Gerard, Alain; Beytout, Jean; Abergel, Armand; Bresson-Hadni, Solange

    2013-01-01

    During 1982–2007, alveolar echinococcosis (AE) was diagnosed in 407 patients in France, a country previously known to register half of all European patients. To better define high-risk groups in France, we conducted a national registry-based study to identify areas where persons were at risk and spatial clusters of cases. We interviewed 180 AE patients about their way of life and compared responses to those of 517 controls. We found that almost all AE patients lived in 22 départements in eastern and central France (relative risk 78.63, 95% CI 52.84–117.02). Classification and regression tree analysis showed that the main risk factor was living in AE-endemic areas. There, most at-risk populations lived in rural settings (odds ratio [OR] 66.67, 95% CI 6.21–464.51 for farmers and OR 6.98, 95% CI 2.88–18.25 for other persons) or gardened in nonrural settings (OR 4.30, 95% CI 1.82–10.91). These findings can help sensitization campaigns focus on specific groups. PMID:23647623

  8. A paradox in physics education in France

    NASA Astrophysics Data System (ADS)

    Smigiel, Eddie; Sonntag, Michel

    2013-07-01

    This paper deals with the nature and the level of difficulty of teaching and learning physics in the first year of undergraduate engineering schools in France. Our case study is based on a survey regarding a classic and basic question in applied physics, and which was conducted with a group of second-year students in a post-baccalaureateThe French baccalaureate (baccalauréat) is the examination students must pass to graduate from high school. undergraduate engineering school. The responses to the survey indicate that many students fall into a kind of mathematical ‘formalism’, which prevents them from understanding the actual physics behind the question. This leads us to believe that we must reconsider the way that physics is taught. An analysis of a physics teaching sequence in French and English undergraduate textbooks confirms the weight given to mathematical formalism in France. When approached from a purely mathematical angle, physics becomes a long and slow process of assimilation of the specific scientific culture that underlies the teaching model used in classes préparatoires, classes that are usually presented as a model of academic excellence. However, this model appears to be less suitable when teaching more ‘ordinary students’, who respond better when taken through a ‘detour’ of the ‘important roots’ of physics. This paper shows that in France historically rooted pedagogical traditions persist, ignoring the latest advances in research on science teaching.

  9. Finding the SurPriSe: A Case Study of a Faculty Learning Community

    ERIC Educational Resources Information Center

    Michel, Roberta M.

    2014-01-01

    This article details a faculty learning community (FLC) that started in 2009 on the campus of a Midwestern University and has evolved into an interdisciplinary research, teaching and social community of practice and learning called SurPriSe. SurPriSe is an acronym that reflects the interest area of the FLC; Sur for surveillance, Pri for privacy,…

  10. Un cas de leishmaniose féline disséminée dans le sud de la France

    PubMed Central

    Pocholle, E.; Reyes-Gomez, E.; Giacomo, A.; Delaunay, P.; Hasseine, L.; Marty, P.

    2012-01-01

    Cet article rapporte un cas de leishmaniose féline disséminée chez un chat (Felis catus) de 14 ans, séropositif pour le FIV et vivant dans les Alpes-Maritimes (sud de la France). Le chat présente des papules érythémateuses ulcérées sur la face et l’encolure, et une lésion proliférative ulcérée sur l’oreille gauche. C’est l’examen histopathologique des lésions cutanées qui permet le diagnostic d’une leishmaniose disséminée, associée à un carcinome épidermoïde de l’oreille. 100 mg d’allopurinol administrés une fois par jour per os pendant quatre mois ont permis la rémission totale des lésions cutanées. Des prélèvements post mortem ont révélé la persistance du parasite dans l’organisme après six mois de traitement. Cet article discute de la sensibilité du chat à la leishmaniose et de son rôle potentiel de réservoir. PMID:22314243

  11. Vaccination coverage with seasonal and pandemic influenza vaccines in children in France, 2009-2010 season.

    PubMed

    Weil-Olivier, Catherine; Lina, Bruno

    2011-09-16

    For a number of years now, GEIG, the Groupement d'Expertise et d'Information sur la Grippe (Influenza Expertise and Information Group) has conducted surveys to monitor seasonal trivalent vaccine uptake in France in adults. During the H1N1 pandemic in 2009, this survey was conducted to determine vaccination uptake for both pandemic and seasonal vaccines. An additional specific questionnaire was used to collect data on vaccination in children under 15 years of age. This additional study was carried out because pandemic vaccination (PV) was offered to the French population and children were listed as a priority target group by the national health authorities, whereas seasonal trivalent inactivated vaccines (TIV) are not recommended in children in France. Overall, we collected 2443 questionnaires on children, including children with underlying conditions (9.2%) for whom TIV vaccination was recommended. Overall, 17.9% of children (438/2443) received at least one shot of PV, compared to 3.4% (83/2443) who received at least one shot of TIV. PV uptake was statistically different between non at-risk and at-risk children (366/2218 [16.5%] vs. 71/225 [31.8%], p<0.0001). This difference was even more significant in the subgroup of children with severe underlying diseases (42.7%, p<0.0001). This confirms that despite the low overall PV uptake in the French population (9%), the specific recommendation for PV for children increased vaccine uptake in this specific population, suggesting that the disease burden of influenza in children is recognised by both practitioners and parents. The next few years will tell us whether TIV uptake in children increases as a consequence of the specific recommendations made for children during the 2009 pandemic wave, or whether it will return to the very low level of 3.4% observed before the pandemic.

  12. [Infant botulism in France, 1991-2009].

    PubMed

    King, L-A; Popoff, M-R; Mazuet, C; Espié, E; Vaillant, V; de Valk, H

    2010-09-01

    Infant botulism is caused by the ingestion of spores of Clostridium botulinum and affects newborns and infants under 12 months of age. Ingested spores multiply and produce botulinum toxin in the digestive tract, which then induces clinical symptoms. A single French case was described in the literature prior to 1991. We describe the cases of infant botulism identified in France between 1991 and 2009. All clinical suspicions of botulism must be declared in France. Biological confirmation of the disease is provided by the National reference laboratory for anaerobic bacteria and botulism at the Pasteur Institute. During this period, 7 cases of infant botulism were identified, 1 per year from 2004 to 2008 and 2 in 2009. The median age of affected infants was 119 days and all were female. All infants presented with constipation and oculomotor symptoms. All were hospitalized and required mechanical ventilation. The infants recovered from their botulism. The diagnosis of infant botulism was biologically confirmed for all patients. One 4-month-old infant was treated with a single dose of the human-derived botulism antitoxin specific for infant botulism types A and B (BabyBIG®). The infants all had different feeding habits ranging from exclusive breast feeding to a mix of formula feeding and solid food consumption. The consumption of honey, the only documented risk food for this disease, was reported for 3 of the infants. The honey had been placed on the pacifier of 2 infants and directly in the mouth of the 3rd by the mother. Infant botulism, a form of botulism that was previously rarely recognized in France, has been reported more frequently during the last 6 years. This disease remains rare but nonetheless severe. In light of recent epidemiological data, efforts to raise awareness among parents of infants and health professionals on the danger of infant botulism and particularly, its association with honey consumption seems necessary.

  13. [Current data on malaria in metropolitan France].

    PubMed

    Danis, M; Legros, F; Thellier, M; Caumes, E

    2002-01-01

    Epidemiological data from the French National Reference Center for Imported Diseases showed that the estimated number of cases of imported malaria in France increased from 5,940 in 1998 to 7,127 in 1999 and 8,056 in 2000. This three-year progression ended in 2001 when the number of estimated cases fell back to 7,223. It was due mainly to the concomitant increase in the number of people traveling to endemic zones especially in Africa. In 2000 the median age of patients with imported malaria in France was 29.5 years and the sex ratio was 1.78. Sixty-three percent of cases involved people of African origin and 37% involved "Westerners". The countries in which contamination occurred were located in tropical Africa (95%), Asia (2.2%), and Latin America (2.7%). During the three year period from 1998 to 2000, there were a total of 13 accidental autochtonous cases of malaria involving patients with no history of travel to tropical areas. The distribution of Plasmodium species involved in imported malaria in France was stable with 83% of cases involving Plasmodium falciparum, 6% involving Plasmodium vivax, 6.5% involving Plasmodium ovale and 1.3% involving Plasmodium malariae. Attacks were clinically uncomplicated in 90 to 95% of cases and severe in 2 to 5% including fatal Plasmodium falciparum malaria in 0.49 to 0.37% of cases. Less than 10% of the 45% of patients claiming use of prophylaxis complied properly. Analysis of the drugs used for curative treatment in 2000 showed an increase in the use of quinine and mefloquine and decrease in the use of halofantrine. The main objectives remain reduction of mortality and improvement of prevention.

  14. How Gaz de France optimizes LNG regasification

    SciTech Connect

    Colonna, J.L.; Lecomte, B.; Caudron, S.

    1986-05-05

    A regasification optimization program was implemented at Montoir-de-Bretagne in 1984, and rapidly accepted by the operators. It has been an important tool for decision-making in the optimizing operation of this liquefied natural gas (LNG) storage and regasification terminal. The models used are regularly and easily updated on the basis of equipment behavior: aging or fouling. The Montoir-de-Bretagne LNG terminal is in the port area of Nates-Saint Nazaire on the Atlantic coast. It was commissioned in 1982 by Gaz de France. This terminal is used for receiving, storing, and regasifying the Algerian LNG received under a contract between Gaz de France and Sonatrach, as well as the LNG imported by Belgium and temporarily routed through France. It is designed to receive 25,000 to 200,000 cu m LNG carriers and has three 120,000 cm m LNG storage tanks. The daily sendout ranges between 6.7 million cu m and 36 million cu m. Monitor terminal supplies mainly Brittany and the Paris area. Two identifical berths allow the simultaneous reception of two LNG carriers. LNG is carried to the storage tanks in 32-in. lines at a rate of 12,000 cu m/hr. Each storage tank is equipped with three submerged 450 cu m/hr pumps with which the LNG is sent from the tanks to the secondary pumps at 8 bar. The nine high-pressure (HP) secondary pumps, with a capacity of either 450 cu m/hr or 180 cu m/hr, raise the LNG pressure to a level at least equal to pipeline pressure prior to revaporization.

  15. France: Thrust and parry over nuclear risks

    SciTech Connect

    Balter, M.

    1997-01-31

    Claims about the health risks posed by nuclear-power installations are always controversial, but nowhere more so than in France, where some 75% of the nation`s electricity is generated from nuclear energy. So, it was no surprise that publication of a study by two French epidemiologists earlier this month claiming to show a link between cases of childhood leukemia and the nuclear-waste reprocessing plant at La Hague on the Normandy coast sparked fireworks in the French press. Several French epidemiologists sharply criticized the study`s methodology and conclusions. Their attacks have now drawn an unusual response from the British Medical Journal (BMJ), in which the paper appeared.

  16. Puumala and Tula hantaviruses in France.

    PubMed

    Plyusnina, Angelina; Deter, Julie; Charbonnel, Nathalie; Cosson, Jean-François; Plyusnin, Alexander

    2007-10-01

    The first genome sequences of Tula (TULV) and Puumala (PUUV) hantaviruses undoubtedly originated from France were recovered from tissue samples of European common voles and bank voles captured in Jura region. Genetic analysis of S and M segments of French PUUV strain revealed its highest similarity to strains from neighboring Belgium and Germany and also from Slovakia. On phylogenetic trees, French PUUV strain was placed within the central European lineage formed by strains from these three countries. Both of our French TULV strains clustered together and formed a distinct, well-supported genetic lineage. PMID:17532080

  17. [National organization of forensic medicine in France].

    PubMed

    Chariot, Patrick

    2012-06-01

    Forensic medicine has long been characterized, in France, by diverse medical practices, which affected its recognition and development. A change was needed, Harmonization procedure includes the development of professional guidelines and allows forensic medicine to look at itself. However, the implementation of the recommendations is still far from complete. A national reform came into effect on 15 January 2011 and has defined a national reform of forensic medicine which includes funding by global budgets instead of fee-for-service. This reform allows easier organization and identification of forensic medicine units. One year later, tangible results are mixed. Forensic medicine is now more clearly identified but properly defined funding criteria are still lacking.

  18. Frances E. Jensen's The Teenage Brain.

    PubMed

    Silveri, Marisa M

    2015-01-01

    The unpredictable and sometimes incomprehensible moods and behaviors of a teenager can be a head-scratching mystery-especially to parents. Hormones, boredom, social media, peer pressure, and drugs and alcohol are just a few of the factors to consider. Frances E. Jensen, M.D., professor and chair of neurology at the University of Pennsylvania and the mother of two sons who are now in their twenties (along with Washington Post health and science reporter and Pulitzer Prize winner Amy Ellis Nutt) look at the emerging science of the adolescent brain and provide advice based on Jensen's own research and experience as a single mother. PMID:27408670

  19. [Cost of multiple sclerosis in France].

    PubMed

    Fromont, A; Lehanneur, M-N; Rollot, F; Weill, A; Clerc, L; Bonithon Kopp, C; Binquet, C; Moreau, T

    2014-01-01

    Multiple sclerosis (MS) is one of the 30 chronic conditions specifically listed by the French healthcare system as a long-term disease (affections de longue durée [ALD]) for which the main health insurance fund (Caisse nationale d'assurance maladie des travailleurs salariés [CNAMTS]) provides full (100%) coverage of healthcare costs. The CNAMTS insures 87% of the French population (52,359,912 of the 60,028,292 inhabitants). The objectives of this study were to evaluate the direct and indirect medical costs of MS among the entire population insured by the CNAMTS in France in 2004. The CNAMTS provided us with access to the ALD database of patients with MS that contains different MS-related expenditures made in 2004. We calculated the overall direct and indirect cost of MS and the cost per patient and per item of expenditure. In 2004, 49,413 patients were registered on the ALD list for MS. Direct cost for MS patients was 469,719,967 €. The direct cost per patient and per year was 9,506 € with variations between regions (French administrative divisions) ranging from 10,800 € in northeastern France (Champagne-Ardenne) to 8,217 € in western France (Pays de la Loire). The different items of expenditure were treatments (44.5%), hospitalization (27.9%), nursing care (5.8%), physiotherapy (5.7%), transport (4%), biology (1.1%), and other (1.5%). During the course of the disease, the overall cost of MS increased slowly during the first 15 years (from 8,000 to 11,000 €), but dramatically the last year of life (23,410 €). The costs of immunomodulator treatments were higher during the first six years after registration on the ALD list. Conversely, physiotherapy costs increased linearly with time during the course of MS. Indirect costs were an estimated 116 million euros in 2004. A disability pension (8,918 € per patient) was perceived by 9,430 patients (19.1%) and a daily allowance (3,317 € per patient) by 9,894 patients (20%). In France, MS has an important

  20. Frances E. Jensen's The Teenage Brain.

    PubMed

    Silveri, Marisa M

    2015-01-01

    The unpredictable and sometimes incomprehensible moods and behaviors of a teenager can be a head-scratching mystery-especially to parents. Hormones, boredom, social media, peer pressure, and drugs and alcohol are just a few of the factors to consider. Frances E. Jensen, M.D., professor and chair of neurology at the University of Pennsylvania and the mother of two sons who are now in their twenties (along with Washington Post health and science reporter and Pulitzer Prize winner Amy Ellis Nutt) look at the emerging science of the adolescent brain and provide advice based on Jensen's own research and experience as a single mother.

  1. Le point sur les amas de galaxies

    NASA Astrophysics Data System (ADS)

    Pierre, M.

    galaxies jouent donc un rôle de premier plan dans toute étude cosmologique et par conséquent, sont indispensables à notre compréhension globale de l'univers. Dans l'introduction générale, nous détaillons cet aspect fondamental en montrant comment l'étude des amas peut contribuer à contraindre les scénarios cosmologiques. Une fois le contexte scientifique délimité, les chapitres suivants s'attachent à présenter les diverses propriétés des amas et leur évolution cosmique observée dans diverses longueurs d'onde principalement dans les domaines visible (galaxies), X (gaz) et radio (gaz et particules). Nous verrons que l'étude détaillée d'un amas implique celle de l'interaction entre ses différentes composantes et est un passage obligé pour remonter au paramètre ultime (ou premier) qu'est sa masse. Loin d'être un détour ennuyeux, ceci sera l'occasion d'aborder des phénomènes physiques extrêmement variés tel l'aspect multi-phases du milieu intra-amas, les sursauts de formation d'étoiles et l'évolution morphologique des galaxies capturées par les amas, ou bien encore, l'interaction entre le plasma intra-amas et les particules relativistes accélérées lors de la fusion entre deux amas. Bien sûr, pour chaque longueur d'onde, nous ne manquerons pas de décrire simplement les techniques d'observation et d'analyse mises en oeuvre ; celles-ci sont particulièrement intéressantes dans le cas de l'instrumentation spatiale. Nous terminerons en présentant des projets d'observatoires pour l'horizon 2010 et leur impact prévu sur l'étude des amas de galaxies.

  2. Acute anaphylactoid reactions during hemodialysis in France.

    PubMed

    Forêt, M; Kuentz, F; Meftahi, H; Milongo, R; Hachache, T; Elsener, M; Dechelette, E; Cordonnier, D

    1987-04-01

    A retrospective survey of anaphylactoid reactions during dialysis in France was conducted. In 52 of 112 hemodialysis units surveyed 111 patients who had suffered one or more anaphylactoid reactions during dialysis were identified. According to the Hamilton/Adkinson classification, in 31 patients reactions were minor, in 54 patients moderate, and in 26 patients severe. Four patients died of their reactions. A preponderance of reactions (75 and 11%) occurred with cuprammonium cellulose hollow-fiber and plate dialyzers, respectively. Severe dialyzer reactions were found to occur more frequently after the long (weekend) interdialytic interval. In an in vitro study, six brands of cuprammonium cellulose hollow-fiber dialyzers were rinsed with water and the eluates analyzed by size exclusion chromatography for contaminant particles. Substantial variation in the amount of extractable material was found between dialyzers of different brands, despite the fact that all dialyzers used membranes from the same manufacturer. Previous data by others has suggested that this extractable material is a derivative of cellulose. Results of our epidemiologic survey in France are similar to those previously reported in the United States and suggest an increased incidence of dialyzer reactions with ethylene oxide-sterilized cuprammonium cellulose dialyzers. The presence of cellulose-derived particles in the rinsing fluid of such dialyzers and the possible increased incidence of reactions after the long (weekend) interdialytic interval suggest that allergy to cellulose-derived particles eluted from cellulosic dialyzers may contribute to dialyzer hypersensitivity reactions.

  3. [Maternal mortality in France, 2007-2009].

    PubMed

    Saucedo, M; Deneux-Tharaux, C; Bouvier-Colle, M-H

    2013-11-01

    To monitor the maternal mortality which is an indicator of the quality of obstetric and intensive care, France has a specific approach since 1996. Recently linkages have been introduced to improve the inclusion of cases. Here are the results for the 2007 to 2009 period. The identification of the pregnancy associated deaths is lying on different data bases that are medical causes of death, birth register and hospital discharges. To document the cases, confidential enquiries are conducted by two assessors on the field; a committee of medical experts analyses the documents, select the underlying cause and assess the quality of health care. Two hundred and fifty-four obstetric deaths were identified from 2007 to 2009 giving the maternal mortality ratio (MMR) of 10.3 per 100,000 births. The maternal age and nationality, the region of deaths are associated to the MMR. The haemorrhages are the leading cause but their ratio is 1.9 versus 2.5 previously; this decrease results from the postpartum haemorrhage by uterine atony going down. The suboptimal care are still frequent (60%) but slightly less than before. The linkage method should be pursued. Maternal mortality is rather stable in France. We may reach more reduction as deaths due to atony decreased as suboptimal care did.

  4. Etude des effets du martelage repetitif sur les contraintes residuelles

    NASA Astrophysics Data System (ADS)

    Hacini, Lyes

    L'assemblage par soudage peut engendrer des contraintes residuelles. Ces contraintes provoquent des fissurations prematurees et un raccourcissement de la duree de vie des composants. Dans ce contexte, le martelage robotise est utilise pour relaxer ces contraintes residuelles. Trois volets sont presentes: le premier est l'evaluation des effets des impacts unitaires repetes sur le champ de contraintes developpe dans des plaques d'acier inoxydable austenitique 304L vierges ou contenant des contraintes residuelles initiales. Dans la deuxieme partie de ce projet, le martelage est applique grace au robot SCOMPI. Les contraintes residuelles induites et relaxees par martelage sont ensuite mesurees par la methode des contours, qui a ete adaptee a cet effet. Dans la troisieme partie, le martelage est modelise par la methode des elements finis. Un modele axisymetrique developpe grace au logiciel ANSYS permet de simuler des impacts repetes d'un marteau elastique sur une plaque ayant un comportement elastoplastique.

  5. 78 FR 37154 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-20

    ... FR 11034, February 26, 1979); 3. Will not affect intrastate aviation in Alaska to the extent that it... Federal Aviation Administration 14 CFR Part 39 RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France (Eurocopter)...

  6. 78 FR 47230 - Airworthiness Directives; Eurocopter France (Eurocopter) Model Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-05

    ...'' under the DOT Regulatory Policies and Procedures (44 FR 11034, February 26, 1979); 3. Will not affect... Federal Aviation Administration 14 CFR Part 39 RIN 2120-AA64 Airworthiness Directives; Eurocopter France... authority of France and are approved for operation in the United States. Pursuant to our bilateral...

  7. 78 FR 66668 - Airworthiness Directives; Eurocopter France (Eurocopter) Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-06

    ... Policies and Procedures (44 FR 11034, February 26, 1979); 3. Will not affect intrastate aviation in Alaska... Federal Aviation Administration 14 CFR Part 39 RIN 2120-AA64 Airworthiness Directives; Eurocopter France... Determination These helicopters have been approved by the aviation authority of France and are approved...

  8. 78 FR 54792 - Airworthiness Directives; Eurocopter France (Eurocopter) Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-06

    ... 12866; 2. Is not a ``significant rule'' under the DOT Regulatory Policies and Procedures (44 FR 11034... Federal Aviation Administration 14 CFR Part 39 RIN 2120-AA64 Airworthiness Directives; Eurocopter France... France and are approved for operation in the United States. Pursuant to our bilateral agreement...

  9. 77 FR 58973 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-25

    ... Policies and Procedures (44 FR 11034, February 26, 1979); 3. Will not affect intrastate aviation in Alaska... Federal Aviation Administration 14 CFR Part 39 RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for the Eurocopter France...

  10. 78 FR 63853 - Airworthiness Directives; Eurocopter France (Eurocopter) Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-25

    ... Regulatory Policies and Procedures (44 FR 11034, February 26, 1979); ] 3. Will not affect intrastate aviation...-033-AD; Amendment 39-17625; AD 2013-21-01] RIN 2120-AA64 Airworthiness Directives; Eurocopter France... These helicopters have been approved by the aviation authority of France and are approved for...

  11. 77 FR 58925 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-25

    ...'' under DOT Regulatory Policies and Procedures (44 FR 11034, February 26, 1979); 3. Will not affect...-17204; AD 2012-19-09] RIN 2120-AA64 Airworthiness Directives; Eurocopter France Helicopters AGENCY... comments. SUMMARY: We are adopting a new airworthiness directive (AD) for Eurocopter France...

  12. 78 FR 33766 - Airworthiness Directives; Eurocopter France (Eurocopter) Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-05

    ... FR 11034, February 26, 1979); 3. Will not affect intrastate aviation in Alaska to the extent that it... Federal Aviation Administration 14 CFR Part 39 RIN 2120-AA64 Airworthiness Directives; Eurocopter France... approved by the aviation authority of France and are approved for operation in the United States....

  13. France: The Move toward Distance Education in the University Sector

    ERIC Educational Resources Information Center

    Mortimer, Peter

    2005-01-01

    France is one of the most modern countries in the world and is a leading force in Europe. A highly literate and well-educated society, France's education statistics for 2003 show 12.1 million French children in primary and secondary education and 2.2 million students in tertiary education. The concept of education as a market commodity--long since…

  14. France: The Challenges of Renewal. Headline Series #282.

    ERIC Educational Resources Information Center

    DePorte, A. W.

    France has responded well to the social, economic, and political challenges which began when that nation was defeated by Germany in 1940. Two major challenges have been to limit internal quarrels which reduce the nation's ability to handle current issues and to accept the fact that France is no longer the greatest power in Europe. Chapter 1…

  15. Social Representation of Gifted Children: A Preliminary Study in France

    ERIC Educational Resources Information Center

    Tavani, Jean Louis; Zenasni, Franck; Pereira-Fradin, Maria

    2009-01-01

    There is a growing recognition of giftedness in France and the need for identification. Social Representations (SR) of gifted children have never been examined in France with an appropriate methodology, yet it is important to do so as the information obtained may help ensure the insertion and inclusion of these children in school and society. The…

  16. Absence of Pneumocystis dihydropteroate synthase mutants in Brittany, France.

    PubMed

    Le Gal, Solène; Robert-Gangneux, Florence; Perrot, Maëla; Rouillé, Amélie; Virmaux, Michèle; Damiani, Céline; Totet, Anne; Gangneux, Jean-Pierre; Nevez, Gilles

    2013-05-01

    Archival Pneumocystis jirovecii specimens from 84 patients monitored at Rennes University Hospital (Rennes, France) were assayed at the dihydropteroate synthase (DHPS) locus. No patient was infected with mutants. The results provide additional data showing that P. jirovecii infections involving DHPS mutants do not represent a public health issue in Brittany, western France.

  17. International Reports on Literacy Research: France and Argentina

    ERIC Educational Resources Information Center

    Malloy, Jacquelynn A., Comp.; Botzakis, Stergios, Comp.

    2006-01-01

    This is a compilation of two separate reports on international literacy research from France and Argentina. In the reports from France, research correspondent Jacques Fijalkow detailed three research projects that included the following: (1) A description of adult literacy skills; (2) An investigation of how study-abroad students were integrated…

  18. 47 CFR 3.46 - Use of gold francs.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 1 2014-10-01 2014-10-01 false Use of gold francs. 3.46 Section 3.46... AUTHORITIES IN MARITIME AND MARITIME MOBILE-SATELLITE RADIO SERVICES Settlement Operations § 3.46 Use of gold francs. An accounting authority must accept accounts presented to it from foreign administrations in...

  19. 47 CFR 3.46 - Use of gold francs.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 1 2012-10-01 2012-10-01 false Use of gold francs. 3.46 Section 3.46... AUTHORITIES IN MARITIME AND MARITIME MOBILE-SATELLITE RADIO SERVICES Settlement Operations § 3.46 Use of gold francs. An accounting authority must accept accounts presented to it from foreign administrations in...

  20. 47 CFR 3.46 - Use of gold francs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Use of gold francs. 3.46 Section 3.46... AUTHORITIES IN MARITIME AND MARITIME MOBILE-SATELLITE RADIO SERVICES Settlement Operations § 3.46 Use of gold francs. An accounting authority must accept accounts presented to it from foreign administrations in...

  1. La punaise diabolique a la conquete de la France

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Halyomorpha halys is now present in France in Alsace and in several neighboring countries (Switzerland and Italy). The potential risk of invasion of H. halys throughout France is considered to be high. Through its natural dispersal, or with human assistance, this insect will likely colonize the majo...

  2. 47 CFR 3.46 - Use of gold francs.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 1 2011-10-01 2011-10-01 false Use of gold francs. 3.46 Section 3.46... AUTHORITIES IN MARITIME AND MARITIME MOBILE-SATELLITE RADIO SERVICES Settlement Operations § 3.46 Use of gold francs. An accounting authority must accept accounts presented to it from foreign administrations in...

  3. 47 CFR 3.46 - Use of gold francs.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 1 2013-10-01 2013-10-01 false Use of gold francs. 3.46 Section 3.46... AUTHORITIES IN MARITIME AND MARITIME MOBILE-SATELLITE RADIO SERVICES Settlement Operations § 3.46 Use of gold francs. An accounting authority must accept accounts presented to it from foreign administrations in...

  4. The Definition of Vocational Diplomas in Germany and France.

    ERIC Educational Resources Information Center

    Mobus, Martine; Verdier, Eric

    1997-01-01

    In both France and Germany, the government, employers' organizations, and unions all participate in defining vocational diplomas based on a national framework of procedures of elaborating and standardizing titles. Important differences between the diploma definition processes in France and Germany may be identified. In Germany, the issue is…

  5. [Training in tropical medicine in France].

    PubMed

    Touze, Jean-Étienne; Laroche, Roland

    2013-10-01

    Tropical medicine was a key element of the medical structures provided by France to our former colonies and, later; to countries within the scope of our international cooperation. hI recent decades, France has drastically reduced its bilateral commitments to countries in the tropics, and especially in sub-Saharan Africa. At the same time, the teaching of tropical medicine, which was highly regarded even beyond our borders, has lost a good deal of its expertise. Initially available in a few large French centers, and ensured by teachers with extensive field experience, training in tropical medicine is now offered in many universities. However; their programs and educational objectives, focusing mainly on infectious and parasitic diseases, no longer meet the healthcare priorities of southern countries, which are facing an epidemiological transition and the rise of non communicable diseases. Few teachers now have recognized expertise in tropical medicine. These changes have had negative consequences for research programs in tropical medicine and for the image of French assistance to developing countries. In this context, the followving perspectives should be considered: 1) training in tropical medicine should be enhanced by the creation of a national diploma recognized by international bodies. 2) The creation of a doctoral course in tropical medicine is a prerequisite for achieving this goal, and the future diploma must include a significant research component. 3) Teaching in tropical medicine must become more practical and be ensured by teachers with extensive field experience. 4) Training in tropical medicine should be part of a bilateral relationship with countries in the tropics, each party contributing its expertise while respecting that of its partners. 5) Training in tropical medicine should be backed uip by high-level scientific research based on enhanced synergy of our current networks (Institute for Research and Development, Network of overseas Pasteur

  6. The Tour de France: a physiological review.

    PubMed

    Lucia, Alejandro; Earnest, Conrad; Arribas, Carlos

    2003-10-01

    On 5 July 2003, the Tour de France (TDF) has celebrated 100th running. Instead of a chimney sweep competing during his free time (as in 1903), the recent winner is a highly trained, professional cyclist whose entire life-style has been dedicated to reach his pinnacle during this event. The TDF has been held successfully for 100 years, but the application of the physiologic sciences to the sport is a relatively recent phenomenon. Although some historical reports help to understand the unique physiological characteristics of this race, scientific studies were not available in Sports Science/Applied Physiology journals until the 1990s. The aim of this article is to review the history of the TDF. Special emphasis is placed on the last decade where classic physiology has been integrated into applied scientific cycling data.

  7. The death of Henry II of France.

    PubMed

    Faria, M A

    1992-12-01

    On June 30, 1559, King Henry II of France (1519-1559), against the advice of his court ministers, participated in a fateful joust. The wooden lance of his younger opponent pierced the King's headgear, shattered into fragments, and penetrated his right orbit and temple. The King survived for 11 days following the mortal wound and was treated by two of the most distinguished physicians of the Renaissance: Ambroise Paré (1510-1590), the master surgeon, and Andreas Vesalius (1514-1564), the great anatomist. The unfortunate event, the nature of the injury, and the medical consultation between these eminent physicians should all be of interest to neurosurgeons. The historical consequences of this event are briefly reviewed. PMID:1432144

  8. Atomic vapor laser isotope separation in France

    NASA Astrophysics Data System (ADS)

    Camarcat, Noel; Lafon, Alain; Perves, Jean-Pierre; Rosengard, Alex; Sauzay, Guy

    1993-05-01

    France has developed a very complete nuclear industry, from mining to reprocessing and radwastes management, and now has a major electro-nuclear park, with 55 power reactors, supplying 75% of the nation's electricity and representing 32% of its energy requirements. The modern multinational EURODIF enrichment plant in Pierrelatte in the south of the country supplies these reactors with enriched uranium as well as foreign utilities (30% exports). It works smoothly and has continuously been improved to reduce operating costs and to gain flexibility and longevity. Investment costs will be recovered at the turn of the century. The plant will be competitive well ahead of an aging production park, with large overcapacity, in other countries. Meanwhile, world needs will increase only slightly during the next 15 years, apart from the Asian Pacific area, but many world governments are becoming well aware of the necessity to progressively resume nuclear energy development worldwide from the year 2000 on.

  9. The LUNEX5 project in France

    NASA Astrophysics Data System (ADS)

    Couprie, M. E.; Benabderrahmane, C.; Betinelli, P.; Bouvet, F.; Buteau, A.; Cassinari, L.; Daillant, J.; Denard, J. C.; Eymard, P.; Gagey, B.; Herbeaux, C.; Labat, M.; Lagarde, B.; Lestrade, A.; Loulergue, A.; Marchand, P.; Marlats, J. L.; Miron, C.; Morin, P.; Nadji, A.; Polack, F.; Pruvost, J. B.; Ribeiro, F.; Ricaud, J. P.; Roy, P.; Tanikawa, T.; Roux, R.; Bielawski, S.; Evain, C.; Szwaj, C.; Lambert, G.; Lifschitz, A.; Malka, V.; Lehe, R.; Rousse, A.; Phuoc, K. Ta; Thaury, C.; Devanz, G.; Luong, M.; Carré, B.; LeBec, G.; Farvacque, L.; Dubois, A.; Lüning, J.

    2013-03-01

    The LUNEX5 (free electron Laser Using a New accelerator for the Exploitation of X-ray radiation of 5th generation) in France aims at investigating the generation of short, intense, and coherent pulses in the soft x-ray region (with two particular targeted wavelengths of 20 and 13 nm). It consists in a single Free Electron Laser (FEL) line with cryo-ready in-vacuum undulators using a Conventional Linear Accelerator (CLA) using the superconducting technology of 400 MeV or a Laser Wake Field Accelerator (LWFA) ranging from 0.4 to 1 GeV with multi-TW or PW lasers. The FEL line can be operated in the seeded (High order Harmonic in Gas seeding) and Echo Enable Harmonic Generation configurations, which performances will be compared. Two pilot user experiments for time-resolved studies of isolated species and magnetization dynamics will take benefit of LUNEX5 FEL radiation.

  10. Effets des electrons secondaires sur l'ADN

    NASA Astrophysics Data System (ADS)

    Boudaiffa, Badia

    Les interactions des electrons de basse energie (EBE) representent un element important en sciences des radiations, particulierement, les sequences se produisant immediatement apres l'interaction de la radiation ionisante avec le milieu biologique. Il est bien connu que lorsque ces radiations deposent leur energie dans la cellule, elles produisent un grand nombre d'electrons secondaires (4 x 104/MeV), qui sont crees le long de la trace avec des energies cinetiques initiales bien inferieures a 20 eV. Cependant, il n'y a jamais eu de mesures directes demontrant l'interaction de ces electrons de tres basse energie avec l'ADN, du principalement aux difficultes experimentales imposees par la complexite du milieu biologique. Dans notre laboratoire, les dernieres annees ont ete consacrees a l'etude des phenomenes fondamentaux induits par impact des EBE sur differentes molecules simples (e.g., N2, CO, O2, H2O, NO, C2H 4, C6H6, C2H12) et quelques molecules complexes dans leur phase solide. D'autres travaux effectues recemment sur des bases de l'ADN et des oligonucleotides ont montre que les EBE produisent des bris moleculaires sur les biomolecules. Ces travaux nous ont permis d'elaborer des techniques pour mettre en evidence et comprendre les interactions fondamentales des EBE avec des molecules d'interet biologique, afin d'atteindre notre objectif majeur d'etudier l'effet direct de ces particules sur la molecule d'ADN. Les techniques de sciences des surfaces developpees et utilisees dans les etudes precitees peuvent etre etendues et combinees avec des methodes classiques de biologie pour etudier les dommages de l'ADN induits par l'impact des EBE. Nos experiences ont montre l'efficacite des electrons de 3--20 eV a induire des coupures simple et double brins dans l'ADN. Pour des energies inferieures a 15 eV, ces coupures sont induites par la localisation temporaire d'un electron sur une unite moleculaire de l'ADN, ce qui engendre la formation d'un ion negatif transitoire

  11. Determinants of measles seroprevalence among pregnant women in Paris, France.

    PubMed

    Bodilis, H; Goffinet, F; Krivine, A; Andrieu, T; Anselem, O; Tsatsaris, V; Rozenberg, F; Launay, O

    2014-08-01

    Non-immune pregnant women are at risk of severe measles. As the measles vaccination is contraindicated during pregnancy, women should be vaccinated before conception or during the postpartum period. Nevertheless, measles serology is not recommended during pregnancy in France, and there are no data available concerning measles susceptibility and its associated risk factors among pregnant women. The socio-demographic determinants of measles seronegativity have been identified in a prospective cohort of 826 pregnant women in Paris, France. Measles seronegativity was 10.41% (95% CI 8.32-12.50). Women from higher socio-economic groups, born in France after 1980, were more frequently seronegative.

  12. Pronatalist policies in Eastern Europe and France.

    PubMed

    Girard, A

    1983-08-01

    Western European fertility rates dropped markedly during the 1930s, and several governments established pronatalist policies. The policies were shortlived as fertility began to rise again after World War 2 and government intervention no longer appeared warranted. In contrast the countries of Eastern Europe retained their relatively high birthrates until measures in the 1950s gave individuals, especially women, greater freedom of choice in childbearing. Divorce laws were liberalized following World War 2, and women's participation in the labor force became widespread. Most European governments, following the example of the Soviet Union, liberalized abortion laws as well, making safe, medical abortion available for social, economic, and medical reasons. Whether or not as a direct result of this legislation, the Eastern European nations experienced such a rapid decline in birthrates that governments, fearing further ramifications, decided to intervene. In 1966, for example, Romania decreed abortion to be illegal except for medical reasons or in the case of rape. Eastern European governments justified their actions by emphasizing their concern about longterm effects. They wanted to avoid the "aging" of their population and the risk of future decrease in total population size. The abortion restrictions were accompanied by widespread efforts to encourage contraception through education, information programs, and postnatal consultations. Incentives were also adopted, and there were adjustments in working conditions for women including longer maternity leave and the opportunity for young mothers to have extended leave. The government's goal is to encourage 2 child families with enough 3 or 4 child families to compensate for 1 child or childless households. Eastern Europe is not alone in its pronatalist policy. France has set similar policies into motion. If this is exceptional among Western countries, it is because French fertility declined about a century before other

  13. Periodicities of hail precipitation in France

    NASA Astrophysics Data System (ADS)

    Hermida, Lucía; Sánchez, José Luis; Berthet, Claude; Dessens, Jean; López, Laura; Hierro, Rodrigo; Wu, Xueke; García-Ortega, Eduardo

    2013-04-01

    The wavelet analysis is a powerful tool appropriated for studying multiscale and non-stationary processes that occur in finite spatial and temporal domains. Its development began with Morlet and, since then, the wavelet transform (WT) has had better applications in Geophysics. However, the characterization of hail precipitation is not exempt from difficulty, since it deals with phenomenon on a small scale, with elevated spatial and temporal variation. The extreme variability of the frequency and distribution of hail is attributed, among other things, to the same process of its formation. The conditions that influence hail formation span from air masses climatology to lower-scale factors such as orography, wind fields, concentration of ice nuclei or temperature. This last factor is important both from a point of view of convective activity as well as its influence in the height of the freezing point. Thus, it would be possible to do comparative analysis between time series of temperature and diverse hail variables; or, rather, to try to establish a relationship between periodicities found and phenomenon such as ENSO (El Niño, Southern Oscillation) or NAO (North-Atlantic Oscillation). France is one of the European countries that is most affected by hail precipitation. Previous climatic studies have been done with the objective of characterizing the long-term variability of distinct variables of this hydrometeor that is present in the time series. These measurements are obtained using networks of hailpads distributed in French territory and managed by ANELFA. Berthet et al. (2011) observed the annual hail frequency in France, finding successions of three years with high values followed by three years of low values; this being calculated as the number of hailfalls per year divided by the number of hailpad stations that were in use during said year. In the present paper, a wavelet analysis was carried out with the objective of detecting the possible existence of

  14. A κ Model for Mainland France

    NASA Astrophysics Data System (ADS)

    Douglas, John; Gehl, Pierre; Bonilla, Luis Fabian; Gélis, Céline

    2010-11-01

    An important parameter for the characterization of strong ground motion at high-frequencies (>1 Hz) is kappa, κ, which models a linear decay of the acceleration spectrum, a( f), in log-linear space (i.e. a( f) = A 0 exp(- π κ f) for f > f E where f is frequency, f E is a low frequency limit and A 0 controls the amplitude of the spectrum). κ is a key input parameter in the stochastic method for the simulation of strong ground motion, which is particularly useful for areas with insufficient strong-motion data to enable the derivation of robust empirical ground motion prediction equations, such as mainland France. Numerous studies using strong-motion data from western North America (WNA) (an active tectonic region where surface rock is predominantly soft) and eastern North America (ENA) (a stable continental region where surface rock is predominantly very hard) have demonstrated that κ varies with region and surface geology, with WNA rock sites having a κ of about 0.04 s and ENA rock sites having a κ of about 0.006 s. Lower κs are one reason why high-frequency strong ground motions in stable regions are generally higher than in active regions for the same magnitude and distance. Few, if any, estimates of κs for French sites have been published. Therefore, the purpose of this study is to estimate κ using data recorded by the French national strong-motion network (RAP) for various sites in different regions of mainland France. For each record, a value of κ is estimated by following the procedure developed by Anderson and Hough (Bull Seismol Soc Am 74:1969-1993, 1984): this method is based on the analysis of the S-wave spectrum, which has to be performed manually, thus leading to some uncertainties. For the three French regions where most records are available (the Pyrenees, the Alps and the Côtes-d’Azur), a regional κ model is developed using weighted regression on the local geology (soil or rock) and source-to-site distance. It is found that the studied

  15. The Quaternary coversands of southwest France

    NASA Astrophysics Data System (ADS)

    Sitzia, Luca; Bertran, Pascal; Bahain, Jean-Jacques; Bateman, Mark D.; Hernandez, Marion; Garon, Henri; de Lafontaine, Guillaume; Mercier, Norbert; Leroyer, Chantal; Queffelec, Alain; Voinchet, Pierre

    2015-09-01

    Detailed stratigraphic analysis and numerical dating (OSL, IRSL, ESR, 14C) of Pleistocene coversands in southwest France enable the construction of a renewed chronostratigraphic framework for sand deposition. The chronological data obtained from sandsheet units testify to the development of transgressive dunefields since at least the Middle Pleistocene (MIS 10). Three main phases of accumulation occurred during the Last Glacial. The oldest one (64-42 ka) is associated with wet sandsheet facies, histic horizons and zibar-type dune fields, which reflect deposition in a context strongly influenced by the groundwater table. The Late Pleniglacial (24-14 ka) corresponds to the main phase of coversand extension in a drier context. Silty gley horizons suggest, however, local interruptions of sand drifting during GS 2.1. Lateglacial stabilization of the coversands may not have occurred before GI-1c (Allerød), which was typified by the development of cumulic arenosols. These were covered by parabolic dunes during the Younger Dryas. The variations in extent of the emerged continental shelf during the glacial-interglacial cycles may explain the uneven geographical distribution of sand deposition through time. Because of coastline retreat up to 100 km north of 45°N during the LGM lowstand, the coversands were unable to reach the northern part of the basin. Comparison with other European regions highlights stronger affinities of the French record with Portugal than with the Netherlands and Great Britain, probably because of reduced influence of permafrost.

  16. [Legionnaire's disease: surveillance in France in 2005].

    PubMed

    Campèse, C; Jarraud, S; Che, D

    2007-11-01

    Legionnaire's disease is a recently described infection and surveillance in France was implemented in 1987. In 2005, 1,527 cases were notified corresponding to a population incidence rate of 2.5 per 100,000. The median age of cases was 61 years [5-100] and the male to female sex ratio was 3.0. The case fatality rate was 11%. One or more risk factors were identified for 1,084 (71%) cases. The majority of cases (91%) was diagnosed by urinary antigen detection and a strain was identified in 276 cases (18%). Legionella pneumophila serogroup 1 infection was confirmed in 95% of cases. A specific exposure during the incubation period was reported for 39% of cases. Travel exposure was reported for 17% and hospital exposure for 7%. Multiple clusters and outbreaks were investigated. The largest one reported was identified in the north Lyon with 34 cases. Since 1997 the incidence of LD has steadily increased. This probably suggests a better detection of cases and an improvement in the surveillance system. In recent years, several new measures concerning prevention and control were implemented. However these efforts must continue particularly in the research domain to improve knowledge of the disease, in order to limit its impact on exposed populations.

  17. Briquet and Briquet's syndrome viewed from France.

    PubMed

    Dongier, M

    1983-10-01

    Briquet's contributions to the description of hysteria have been almost completely forgotten in France. One may wonder how he, as well as contemporary French psychiatrists, would react to the approach to hysteria introduced and officialized by DSM III. In particular, its fragmentation into syndromes without apparent link to each other (psychogenic amnesia, conversion disorders, histrionic personality disorder, etc.) and its psychological causation, unbalanced by the consideration of organic factors in etiology, may raise questions. The correlation of conversion disorders with hysterical personality remains a feature of the WHO classification (ICD 9), as well as a feature of French contemporary texts, although it is no longer viewed as a regular association by American psychiatry. It may be that cultural factors lead, as suggested by Brisset, to a repression of conversion phenomena and of hyperexpressivity of affects replaced by more psychosomatic disorders in many contemporary societies. Finally, one may question whether the choice of the term "Briquet Syndrome" is appropriate, as many of the patients described by him did not have the chronic and malignant course described by Guze: It tends to limit hysteria to one end (the most severe one) of a spectrum of disorders.

  18. Briquet and Briquet's syndrome viewed from France.

    PubMed

    Dongier, M

    1983-10-01

    Briquet's contributions to the description of hysteria have been almost completely forgotten in France. One may wonder how he, as well as contemporary French psychiatrists, would react to the approach to hysteria introduced and officialized by DSM III. In particular, its fragmentation into syndromes without apparent link to each other (psychogenic amnesia, conversion disorders, histrionic personality disorder, etc.) and its psychological causation, unbalanced by the consideration of organic factors in etiology, may raise questions. The correlation of conversion disorders with hysterical personality remains a feature of the WHO classification (ICD 9), as well as a feature of French contemporary texts, although it is no longer viewed as a regular association by American psychiatry. It may be that cultural factors lead, as suggested by Brisset, to a repression of conversion phenomena and of hyperexpressivity of affects replaced by more psychosomatic disorders in many contemporary societies. Finally, one may question whether the choice of the term "Briquet Syndrome" is appropriate, as many of the patients described by him did not have the chronic and malignant course described by Guze: It tends to limit hysteria to one end (the most severe one) of a spectrum of disorders. PMID:6357422

  19. Identifying barriers to Muslim integration in France

    PubMed Central

    Adida, Claire L.; Laitin, David D.; Valfort, Marie-Anne

    2010-01-01

    Is there a Muslim disadvantage in economic integration for second-generation immigrants to Europe? Previous research has failed to isolate the effect that religion may have on an immigrant family's labor market opportunities because other factors, such as country of origin or race, confound the result. This paper uses a correspondence test in the French labor market to identify and measure this religious effect. The results confirm that in the French labor market, anti-Muslim discrimination exists: a Muslim candidate is 2.5 times less likely to receive a job interview callback than is his or her Christian counterpart. A high-n survey reveals, consistent with expectations from the correspondence test, that second-generation Muslim households in France have lower income compared with matched Christian households. The paper thereby contributes to both substantive debates on the Muslim experience in Europe and methodological debates on how to measure discrimination. Following the National Academy of Sciences’ 2001 recommendations on combining a variety of methodologies and applying them to real-world situations, this research identifies, measures, and infers consequences of discrimination based on religious affiliation, controlling for potentially confounding factors, such as race and country of origin. PMID:21098283

  20. The impact of international recruitment on healthcare delivery in France.

    PubMed

    Rusu, Ioana; Planck, Ashlee

    2010-01-01

    Mobility of Health Professionals (MoHProf), the European Commission-sponsored collaborative project, examines current trends in the mobility of health professionals to, from and within the European Union (EU). The French national level project studies the relevance of international recruitment in France by studying migratory flows and the "pull" and "preventive" factors influencing immigration of foreign health professionals to France. Using the results of the study, in this article, firstly, we quantify the phenomenon of health professional immigration and secondly, we discuss the 'pull' and 'preventive' factors. We argue that diploma and professional recognition is a variable that acts both as a 'pull' and 'preventive' factor at once and has one of the most significant impacts on international recruitment in France. We, therefore, analyze its impact on the recruitment of health professionals having obtained their diploma and qualifications abroad and the possible consequences on healthcare delivery in France. PMID:21155427

  1. 20. Photocopy of photograph (From Frances Rand Smith Collection, California ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    20. Photocopy of photograph (From Frances Rand Smith Collection, California Historical Society) Photographer unknown, Date unknown VIEW OF CHURCH FROM REAR - Mission San Miguel Arcangel, Highway 101, San Miguel, San Luis Obispo County, CA

  2. 16. Photocopy of photograph (from Frances Rand Smith Collection, California ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. Photocopy of photograph (from Frances Rand Smith Collection, California Historical Society, 1900) Photographer unknown, Date unknown FRONT VIEW OF MISSION, c. 1900 - Mission San Miguel Arcangel, Highway 101, San Miguel, San Luis Obispo County, CA

  3. Chirac of France: A new leader of the west?

    SciTech Connect

    Moiesi, D.

    1995-11-01

    In foreign and security policy the issues for France are contradictory nature of Chirac`s goals or in the incompatibility of the means to those ends. Chirac`s modernized Gaullist formula for independent French action to meet the exigencies of the post-Cold War world may be irreconcilable with the constraints and demands of the European unification process. The goal of independence may not mesh with the retention of influence. An immediate, concrete example is the apparent contradiction between France`s European and world ambitions and its resumption of nuclear testing. Four foreign policy themes have dominated the initial months of Chirac`s presidency: the war in Bosnia, nuclear testing, European relations, and the conflict in Algeria and its repercussions in France. These themes are examined in more detail.

  4. A short account of forensic dentistry in France.

    PubMed

    Riaud, Xavier

    2016-01-01

    The earliest records and more recent cases where forensic dentistry has been used to identify bodies in France are described. The establishment of the French Society of Forensic Odontology is detailed.

  5. Endothelial SUR-8 Acts in an ERK-Independent Pathway During Atrioventricular Cushion Development

    PubMed Central

    Yi, Jing; Chen, Muyun; Wu, Xiaohui; Yang, Xiao; Xu, Tian; Zhuang, Yuan; Han, Min; Xu, Rener

    2010-01-01

    SUR-8, a conserved leucine-rich repeats protein, was first identified as a positive regulator of Ras pathway in Caenorhabditis elegans. Biochemical studies indicated that SUR-8 interacts with Ras and Raf, leading to the elevated ERK activity. However, the physiological role of SUR-8 during mammalian development remains unclear. Here we found that germline deletion of SUR-8 in mice resulted in early embryonic lethality. Inactivated SUR-8 specifically in mouse endothelial cells (ECs) revealed that SUR-8 is essential for embryonic heart development. SUR-8 deficiency in ECs resulted in late embryonic lethality, and the mutant mice displayed multiple cardiac defects. The reduced endothelial-mesenchymal transformation (EMT) and the reduced mesenchyme proliferation phase were observed in the atrioventricular canal (AVC) within the mutant hearts, leading to the formation of hypoplastic endocardial cushions. However, ERK activation did not appear to be affected in mutant ECs, suggesting that SUR-8 may act in an ERK-independent pathway to regulate AVC development. Developmental Dynamics 239:2005–2013, 2010 © 2010 Wiley-Liss, Inc. PMID:20549726

  6. History of infrared optronics in France

    NASA Astrophysics Data System (ADS)

    Fouilloy, J. P.; Siriex, Michel B.

    1995-09-01

    In France, the real start of work on the applications of infrared radiations occurred around 1947 - 1948. During many years, technological research was performed in the field of detectors, optical material, modulation techniques, and a lot of measurements were made in order to acquire a better knowledge of the propagation medium and radiation of IR sources, namely those of jet engines. The birth of industrial infrared activities in France started with the Franco-German missile guidance programs: Milan, HOT, Roland and the French air to air missile seeker programs: R530, MAGIC. At these early stages of IR technologies development, it was a great technical adventure for both the governmental agencies and industry to develop: detector technology with PbS and InSb, detector cooling for 3 - 5 micrometer wavelength range, optical material transparent in the infrared, opto mechanical design, signal processing and related electronic technologies. Etablissement Jean Turck and SAT were the pioneers associated with Aerospatiale, Matra and under contracts from the French Ministry of Defence (DGA). In the 60s, the need arose to enhance night vision capability of equipment in service with the French Army. TRT was chosen by DGA to develop the first thermal imagers: LUTHER 1, 2, and 3 with an increasing number of detectors and image frequency rate. This period was also the era in which the SAT detector made rapid advance. After basic work done in the CNRS and with the support of DGA, SAT became the world leader of MCT photovoltaic detector working in the 8 to 12 micron waveband. From 1979, TRT and SAT were given the responsibility for the joint development and production of the first generation French thermal imaging modular system so-called SMT. Now, THOMSON TTD Optronique takes over the opto-electronics activities of TRT. Laser based systems were also studied for military application using YAG type laser and CO2 laser: Laboratoire de Marcousis, CILAS, THOMSON CSF and SAT have

  7. France, Shaded Relief and Colored Height

    NASA Technical Reports Server (NTRS)

    2003-01-01

    This image of France was generated with data from the Shuttle Radar Topography Mission (SRTM). For this broad view the resolution of the data was reduced to 6 arcseconds (about 185 meters north-south and 127 meters east-west), resampled to a Mercator projection, and the French border outlined. Even at this decreased resolution the variety of landforms comprising the country is readily apparent.

    The upper central part of this scene is dominated by the Paris Basin, which consists of a layered sequence of sedimentary rocks. Fertile soils over much of the area make good agricultural land. The Normandie coast to the upper left is characterized by high, chalk cliffs, while the Brittany coast (the peninsula to the left) is highly indented where deep valleys were drowned by the sea, and the Biscay coast to the southwest is marked by flat, sandy beaches.

    To the south, the Pyrenees form a natural border between France and Spain, and the south-central part of the country is dominated by the ancient Massif Central. Subject to volcanism that has only subsided in the last 10,000 years, these central mountains are separated from the Alps by the north-south trending Rhone River Basin.

    Two visualization methods were combined to produce the image: shading and color coding of topographic height. The shade image was derived by computing topographic slope in the northwest-southeast direction, so that northwest slopes appear bright and southeast slopes appear dark. Color coding is directly related to topographic height, with green at the lower elevations, rising through yellow and tan, to white at the highest elevations.

    Elevation data used in this image were acquired by the Shuttle Radar Topography Mission aboard the Space Shuttle Endeavour, launched on Feb. 11, 2000. SRTM used the same radar instrument that comprised the Spaceborne Imaging Radar-C/X-Band Synthetic Aperture Radar (SIR-C/X-SAR) that flew twice on the Space Shuttle Endeavour in 1994. SRTM was designed to

  8. Diversity of the Insect Visitors on Calluna vulgaris (Ericaceae) in Southern France Heathlands

    PubMed Central

    Descamps, Charlotte; Moquet, Laura; Migon, Marc; Jacquemart, Anne-Laure

    2015-01-01

    As part of an ongoing research project on the pollination networks in European heathlands, the objective of this study was to assess the insect visitor guild on Calluna vulgaris (L.) Hull (Ericaceae). We focused the study on a region renowned for its largely well-preserved heathlands, the Cévennes National Park, Southern France. In 2013, flower visitors were observed over 3 d per site, in four heathland sites at mont Lozère. Honeybees (Apis mellifera L.) were the main visitors (62–88% of total visitors). Besides honeybees, a high diversity of visitors was detected with 57 different species identified (42 Diptera and 15 Hymenoptera). Hoverflies (Syrphidae, Diptera) visitors were abundant and diverse, especially individuals belonging to the genera Eristalis and Episyrphus. The reported diversity of visitors was probably due to the preservation of large heathland areas at mont Lozère and to the generalist pollination system of C. vulgaris. RESUME. Cette étude fait partie d’un projet de recherche en cours sur les réseaux de pollinisation dans les landes européennes. Son objectif est d’évaluer la guilde des insectes visiteurs de Calluna vulgaris (L.) Hull (Ericaceae). Cette étude se déroule dans une région réputée pour ses landes globalement bien préservées: le Parc natinal des Cévennes, situé dans le sud de la France. En 2013, les insectes visiteurs ont été observés durant trois jours par site, dans quatre sites au mont Lozère. Les abeilles domestiques (A. mellifera L.) sont les visiteurs principaux (62–88% du nombre total de visiteurs). Outre les abeilles domestiques, une diversité importante de visiteurs est constatée: 57 espèces ont été identifiées (42 appartenant à l'ordre des Diptères et 15 à l'ordre des Hyménoptères). Les syrphes (Syrphidae, Diptera) sont abondants et diversifiés, en particulier les genres Eristalis et Episyrphus. La diversité de visiteurs observée peut certainement s’expliquer par la préservation de

  9. The spatial distribution of Mustelidae in France.

    PubMed

    Calenge, Clément; Chadoeuf, Joël; Giraud, Christophe; Huet, Sylvie; Julliard, Romain; Monestiez, Pascal; Piffady, Jérémy; Pinaud, David; Ruette, Sandrine

    2015-01-01

    We estimated the spatial distribution of 6 Mustelidae species in France using the data collected by the French national hunting and wildlife agency under the "small carnivorous species logbooks" program. The 1500 national wildlife protection officers working for this agency spend 80% of their working time traveling in the spatial area in which they have authority. During their travels, they occasionally detect dead or living small and medium size carnivorous animals. Between 2002 and 2005, each car operated by this agency was equipped with a logbook in which officers recorded information about the detected animals (species, location, dead or alive, date). Thus, more than 30000 dead or living animals were detected during the study period. Because a large number of detected animals in a region could have been the result of a high sampling pressure there, we modeled the number of detected animals as a function of the sampling effort to allow for unbiased estimation of the species density. For dead animals -- mostly roadkill -- we supposed that the effort in a given region was proportional to the distance traveled by the officers. For living animals, we had no way to measure the sampling effort. We demonstrated that it was possible to use the whole dataset (dead and living animals) to estimate the following: (i) the relative density -- i.e., the density multiplied by an unknown constant -- of each species of interest across the different French agricultural regions, (ii) the sampling effort for living animals for each region, and (iii) the relative detection probability for various species of interest. PMID:25811456

  10. The Spatial Distribution of Mustelidae in France

    PubMed Central

    Calenge, Clément; Chadoeuf, Joël; Giraud, Christophe; Huet, Sylvie; Julliard, Romain; Monestiez, Pascal; Piffady, Jérémy; Pinaud, David; Ruette, Sandrine

    2015-01-01

    We estimated the spatial distribution of 6 Mustelidae species in France using the data collected by the French national hunting and wildlife agency under the “small carnivorous species logbooks” program. The 1500 national wildlife protection officers working for this agency spend 80% of their working time traveling in the spatial area in which they have authority. During their travels, they occasionally detect dead or living small and medium size carnivorous animals. Between 2002 and 2005, each car operated by this agency was equipped with a logbook in which officers recorded information about the detected animals (species, location, dead or alive, date). Thus, more than 30000 dead or living animals were detected during the study period. Because a large number of detected animals in a region could have been the result of a high sampling pressure there, we modeled the number of detected animals as a function of the sampling effort to allow for unbiased estimation of the species density. For dead animals -- mostly roadkill -- we supposed that the effort in a given region was proportional to the distance traveled by the officers. For living animals, we had no way to measure the sampling effort. We demonstrated that it was possible to use the whole dataset (dead and living animals) to estimate the following: (i) the relative density -- i.e., the density multiplied by an unknown constant -- of each species of interest across the different French agricultural regions, (ii) the sampling effort for living animals for each region, and (iii) the relative detection probability for various species of interest. PMID:25811456

  11. Metal music and mental health in France.

    PubMed

    Recours, Robin; Aussaguel, François; Trujillo, Nick

    2009-09-01

    Although numerous authors have associated metal music with social problems such as suicide, self-destruction and Satanism, few studies have been undertaken to examine the mental health of fans of heavy metal music. This study attempts to determine if there is a link between mental health and the enjoyment of this type of music in France. The researchers surveyed 333 fans of metal music. Their mental health was evaluated by the Hospital Anxiety and Depression Scale (HADS), a widely used instrument that measures anxiety and depression. The scores of the sample of metal music fans were then compared to the scores that reveal possible, probable, or severe mental disorders. Qualifying variables included age, gender, status, education, motivation and participation in metal music culture. The results indicated that fans of metal music are mainly young adults (median age = 22.67, SD = 5.29) and tend to be male (87.85 percent). As a whole, metal music fans have levels of anxiety and depression that are similar to and lower than levels in the general population. Specifically, <5 percent of metal music fans surveyed showed pathological symptoms. Subjects that scored higher levels of anxiety and depression were those that had literary and/or arts backgrounds rather than scientific backgrounds, that wrote metal music lyrics, that consumed alcohol and that engaged in the body modification practice of scarification. This study suggests that opponents of metal music should re-examine the basis for their criticism. More scholarly research is needed to better understand the effects of metal music on fans and on society.

  12. The spatial distribution of Mustelidae in France.

    PubMed

    Calenge, Clément; Chadoeuf, Joël; Giraud, Christophe; Huet, Sylvie; Julliard, Romain; Monestiez, Pascal; Piffady, Jérémy; Pinaud, David; Ruette, Sandrine

    2015-01-01

    We estimated the spatial distribution of 6 Mustelidae species in France using the data collected by the French national hunting and wildlife agency under the "small carnivorous species logbooks" program. The 1500 national wildlife protection officers working for this agency spend 80% of their working time traveling in the spatial area in which they have authority. During their travels, they occasionally detect dead or living small and medium size carnivorous animals. Between 2002 and 2005, each car operated by this agency was equipped with a logbook in which officers recorded information about the detected animals (species, location, dead or alive, date). Thus, more than 30000 dead or living animals were detected during the study period. Because a large number of detected animals in a region could have been the result of a high sampling pressure there, we modeled the number of detected animals as a function of the sampling effort to allow for unbiased estimation of the species density. For dead animals -- mostly roadkill -- we supposed that the effort in a given region was proportional to the distance traveled by the officers. For living animals, we had no way to measure the sampling effort. We demonstrated that it was possible to use the whole dataset (dead and living animals) to estimate the following: (i) the relative density -- i.e., the density multiplied by an unknown constant -- of each species of interest across the different French agricultural regions, (ii) the sampling effort for living animals for each region, and (iii) the relative detection probability for various species of interest.

  13. [History of clinical pharmacology in France: adaptation, evaluation, defense and illustration of drug in France 1978-1981].

    PubMed

    Montastruc, Paul

    2014-01-01

    This text illustrates some unknown aspects of the history and beginnings of clinical pharmacology in France in the late 1970s and early 1980s From the current situation, development and objectives of clinical pharmacology are recalled as well as obstacles necessary to overcome to change the paradigm in the field of drug evaluation and appropriate use in France. The text recalls this important moment where French medicine and medical pharmacology entered the modern era.

  14. Lignes directrices simplifiées sur les lipides

    PubMed Central

    Allan, G. Michael; Lindblad, Adrienne J.; Comeau, Ann; Coppola, John; Hudson, Brianne; Mannarino, Marco; McMinis, Cindy; Padwal, Raj; Schelstraete, Christine; Zarnke, Kelly; Garrison, Scott; Cotton, Candra; Korownyk, Christina; McCormack, James; Nickel, Sharon; Kolber, Michael R.

    2015-01-01

    Résumé Objectif Produire un guide de pratique clinique comportant une approche simplifiée à la prévention primaire des maladies cardiovasculaires (MCV), en insistant sur l’estimation du risque de MCV et la prise en charge des profils lipidiques à l’intention des cliniciens de soins primaires et leurs équipes; nous avons recherché la contribution de professionnels des soins primaires qui n’avaient que peu ou pas de conflits d’intérêts et nous nous sommes concentrés sur les données probantes de la plus haute qualité accessibles. Méthodes Neuf professionnels de la santé (4 médecins de famille, 2 internistes, 1 infirmière praticienne, 1 infirmière autorisée et 1 pharmacienne) et 1 membre non votant (pharmacienne gestionnaire de projet) formaient le comité principal appelé le Lipid Pathway Committee (le comité). La sélection des membres s’est fondée sur la profession, le milieu de pratique et son emplacement. Les membres ont divulgué tous leurs conflits d’intérêts potentiels ou réels. Le processus d’élaboration des lignes directrices était itératif et s’appuyait sur des affichages en ligne, une révision détaillée des données probantes, des réunions par téléphone et en ligne. Le comité a cerné 12 questions prioritaires à répondre. Le groupe de révision des données probantes a répondu à ces questions. À la suite d’un examen des réponses, les principales recommandations ont été formulées par consensus du comité. Nous avons produit une ébauche des lignes directrices qui a ensuite été peaufinée, distribuée à un groupe de cliniciens (médecins de famille, autres spécialistes, pharmaciens, infirmières et infirmières praticiennes) et à des patients pour obtenir de la rétroaction, la réviser en conséquence et le comité l’a ensuite finalisée. Recommandations Des recommandations sont présentées concernant le dépistage et les analyses, les évaluations du risque, le suivi, de même que le r

  15. Structure of thermotoga maritima stationary phase survival protein SurE : a novel acid phosphatase.

    SciTech Connect

    Zhang, R.-G; Skarina, T.; Katz, J. E.; Khachatryan, A; Vyas, S.; Arrowsmith, C. H.; Clarke, S.; Edwards, A.; Joachimiak, A.; Savchenko, A.; Biosciences Division; Univ. of Toronto; Univ. of California; Clinical Genomics Centre /Proteomics, Univ. Health Network

    2001-11-01

    Background: The rpoS, nlpD, pcm, and surE genes are among many whose expression is induced during the stationary phase of bacterial growth. rpoS codes for the stationary-phase RNA polymerase {sigma} subunit, and nlpD codes for a lipoprotein. The pcm gene product repairs damaged proteins by converting the atypical isoaspartyl residues back to L-aspartyls. The physiological and biochemical functions of surE are unknown, but its importance in stress is supported by the duplication of the surE gene in E. coli subjected to high-temperature growth. The pcm and surE genes are highly conserved in bacteria, archaea, and plants. Results: The structure of SurE from Thermotoga maritima was determined at 2.0 Angstroms. The SurE monomer is composed of two domains; a conserved N-terminal domain, a Rossman fold, and a C-terminal oligomerization domain, a new fold. Monomers form a dimer that assembles into a tetramer. Biochemical analysis suggests that SurE is an acid phosphatase, with an optimum pH of 5.5-6.2. The active site was identified in the N-terminal domain through analysis of conserved residues. Structure-based site-directed point mutations abolished phosphatase activity. T. maritima SurE intra- and intersubunit salt bridges were identified that may explain the SurE thermostability. Conclusions: The structure of SurE provided information about the protein's fold, oligomeric state, and active site. The protein possessed magnesium-dependent acid phosphatase activity, but the physiologically relevant substrate(s) remains to be identified. The importance of three of the assigned active site residues in catalysis was confirmed by site-directed mutagenesis.

  16. Scientific research at the Laboratoire Arago (Banyuls, France) in the twentieth century: Edouard Chatton, the "master", and André Lwoff, the "pupil".

    PubMed

    Soyer-Gobillard, Marie-Odile

    2002-03-01

    Edouard Chatton (1883-1947) began his scientific career in the Pasteur Institute, where he made several important discoveries regarding pathogenic protists (trypanosomids, Plasmodium, toxoplasms, Leishmania). In 1908 he married a "Banyulencque", Marie Herre; from 1920, he focused his research on marine protists. He finished his career as Professor at the Sorbonne (Paris) and director of the Laboratoire Arago in Banyuls-sur-mer, where he died in 1947. André Lwoff (1902-1994) lived several scientific lives in addition to his artistic and family life. But it is the study of protists that filled his first life after he encountered the exceptional Master who was Chatton. Lwoff's father was a psychiatrist and his mother an artist sculptor. He became a Doctor of Medicine in 1927 and then a Doctor of Sciences in 1932, his thesis dealing with biochemical aspects of protozoa nutrition. He met Chatton in 1921 and until Chatton's death--their meetings, first in Roscoff and then in Banyuls-sur-mer, were numerous and their collaboration very close. Their monograph on apostome ciliates was one of the peaks of this collaboration. In 1938, Lwoff was made director of the Microbial Physiology Department at the Pasteur Institute in Paris, where he began a new life devoted to bacteria, and then to viruses, before pursuing his career as director of the Cancer Research Institute in Villejuif (France). Lwoff was awarded the Nobel Prize in Physiology or Medicine in 1965. He died in Banyuls in 1994. "Master" and "pupil" had in common perseverance in their scientific work, conception and observation, a critical sense and rigor but also a great artistic sensibility that painting and drawing in the exceptional surroundings of Banyuls-sur-mer had fulfilled.

  17. Improving the Quality of Care of Long-Stay Nursing Home Residents in France.

    PubMed

    Rolland, Yves; Mathieu, Celine; Piau, Christine; Cayla, Françoise; Bouget, Catherine; Vellas, Bruno; de Souto Barreto, Philipe

    2016-01-01

    The aim of the Impact d'une démarche QUAlité sur l'évolution des pratiques et le déclin fonctionnel des Résidents en Établissement d'hébergement pour personnes âgées dépendantes (IQUARE) study was to examine the effects of a global intervention comprising professional support and education for nursing home (NH) staff on quality indicators (QIs) and functional decline and emergency department (ED) transfers of residents. One hundred seventy-five NHs in France (a total of 6,275 residents randomly selected from NHs) volunteered and were enrolled in a nonrandomized controlled multicenter individually customize trial with 18-month follow-up. NHs were allocated to a quality audit and feedback intervention (control group: 90 NHs, 3,258 residents) or to the quality audit and feedback intervention plus collaborative work meetings between a hospital geriatrician and NH staff (experimental group: 85 NHs, 3,017 residents). At the NH level, prevalence of assessment of kidney function, cognitive function, risk of pressure ulcers, behavioral disturbances, depression, pain, weight measurement, and transfer to the ED were recorded. Ability to perform basic activities of daily living was assessed at the resident level. At baseline, NH QIs were generally low (with large standard deviations), and annual rate of transfer to the ED was high (~20%) and similar in both groups. The intervention had a significant positive effect on the prevalence of assessment of pressure ulcer risk, depression, pain, and prevalence of ED transfers. It had no significant effect on functional decline. Large-scale efforts to improve QIs involving collaboration between hospital and NH providers and based on audit and collaborative discussion are feasible and improve some aspects of quality of care in NHs.

  18. Impacts of the January 2014 extreme rainfall event on transportation network in the Alps Maritimes (France)

    NASA Astrophysics Data System (ADS)

    Voumard, Jeremie; Penna, Ivanna; Jaboyedoff, Michel; Derron, Marc-Henri

    2014-05-01

    Road networks in mountain areas are highly inter-dependent systems, and hillslope processes such as landslides are main drivers of infrastructure detriment and transportation disruptions. Besides the structural damages, economic losses are also related to road and surrounding slope maintenance, as well as due to the disruption of transportation of goods, inaccessibility of tourist resorts, etc. 16-17th January 2014, an intense rainfall event was recorded in the Alpes Maritimes from the southern part of France. According to meteorological data, it was the highest since the 70's. This rainfall triggered numerous landslides (rockfalls, earth flows and debris flows), mostly on January 17th. There were no casualties registered due to hillslope processes, but several houses were damaged, some populations living in the Var valley along the RM 2205 road were isolated, and several roads were partially and totally blocked. 1.5 km upstream the village of Saint-Sauveur-sur-Tinée, 150 m3 of rock detached from the slope and blocked the road, after which temporary traffic interruptions due to road works lasted around one week. In the Menton area, where hillslopes are highly urbanized, the volume of rocks involved in slope failures was so large that materials removed to reestablish the traffic had to be placed in transitory storage sites. The average landslide volume was estimated at around 100 m3. Most of the landslides occurred in slopes cut during road and houses constructions. Several trucks were needed to clean up materials, giving place to traffic jams, etc. (some single events reached around 400 m3). The aim of this study is to document the impact on transportation networks caused by this rainfall event. Damages and consequences for the traffic were documented during a field visit, obtained from secondary information, as well as by the aid of a drone in the case of inaccessible areas.

  19. Getting ready for crops' adaptation to climate change in France ; two complementary experiences : what lessons can we draw from them ?

    NASA Astrophysics Data System (ADS)

    de Noblet, Nathalie; Levrault, Frédéric; Caubel, Julie; Garcia de CortazarAtauri, Iñaki; Vivant, Anne-Charlotte; Wieruszeski, Sophie; Launay, Marie

    2016-04-01

    The french agriculture is a sector particularly concerned by climate change: the scale of the already observed impacts and the expected climatic evolutions prevent any hesitation on the necessity of an adaptation of agriculture. This assessment is simultaneously shared by the scientific, political as well as the economic communities. However, a generalized and organized movement of adaptation of agriculture has difficulty in emerging in France and maybe in other countries, while past decades have seen the development of research projects and publications on the adaptation to climate change. Two parallel initiatives have been run in France over the past 5 years, that happen to share the same name while not involving the same actors: an observatory of climate change and agriculture functioning (ORACLE: Observatoire Régional sur l'Agriculture et le Changement Climatique), and a nationally funded research project that explores with various tools risks and opportunities for agro-ecosystems in the future in France (ORACLE: Opportunities and Risks of Agrosystems & forests in response to CLimate, socio-economic and policy changEs in France). The Observatory is carrying on a regional analysis of historical trends of both climatic and agricultural variables. It has for ambition to help the agricultural world to better integrate the evolution of climate into its decision-making, for purposes of adaptation as well as mitigation. The observatory is run since year 2011 in the Poitou-Charentes region and is now being implemented in other regions in France (Aquitaine, Pays de la Loire, Champagne Ardennes, Normandie). The research project has looked into the impacts of various scenarios of climate change through the use of various techniques : mechanistic models (Calvet et al. 2013, Wu et al. 2016) and eco-climatic indicators (Caubel et al. 2015). Informations regarding risks and opportunities for large crops in France is in the process being assessed though those tools and

  20. SUR1-Associated Mechanisms Are Not Involved in Ischemic Optic Neuropathy 1 Day Post-Injury

    PubMed Central

    Nicholson, James D.; Guo, Yan; Bernstein, Steven L.

    2016-01-01

    Ischemia-reperfusion injury after central nervous system (CNS) injury presents a major health care challenge with few promising treatments. Recently, it has become possible to reduce edema after CNS injury by antagonizing a sulfonylurea receptor 1 (SUR1) regulated ion channel expressed after injury. SUR1 upregulation after injury is a necessary precondition for the formation of this channel, and has been implicated in white matter injury after clinical spinal cord trauma. Glibenclamide, an SUR1 antagonist, appears to have neuroprotective effect against cerebral stroke in an open-label small clinical trial and great effectiveness in reducing damage after varied experimental CNS injury models. Despite its importance in CNS injuries, SUR1 upregulation appears to play no part in rodent anterior ischemic optic neuropathy (rAION) injury as tested by real-time PCR and immunohistochemical staining of rAION-injured rat optic nerve (ON). Furthermore, the SUR1 antagonist glibenclamide administered immediately after rAION injury provided no protection to proximal ON microvasculature 1 day post-injury but may reduce optic nerve head edema in a manner unrelated to ON SUR1 expression. Our results suggest that there may be fundamental differences between rAION optic nerve ischemia and other CNS white matter injuries where SUR1 appears to play a role. PMID:27560494

  1. SUR1-Associated Mechanisms Are Not Involved in Ischemic Optic Neuropathy 1 Day Post-Injury.

    PubMed

    Nicholson, James D; Guo, Yan; Bernstein, Steven L

    2016-01-01

    Ischemia-reperfusion injury after central nervous system (CNS) injury presents a major health care challenge with few promising treatments. Recently, it has become possible to reduce edema after CNS injury by antagonizing a sulfonylurea receptor 1 (SUR1) regulated ion channel expressed after injury. SUR1 upregulation after injury is a necessary precondition for the formation of this channel, and has been implicated in white matter injury after clinical spinal cord trauma. Glibenclamide, an SUR1 antagonist, appears to have neuroprotective effect against cerebral stroke in an open-label small clinical trial and great effectiveness in reducing damage after varied experimental CNS injury models. Despite its importance in CNS injuries, SUR1 upregulation appears to play no part in rodent anterior ischemic optic neuropathy (rAION) injury as tested by real-time PCR and immunohistochemical staining of rAION-injured rat optic nerve (ON). Furthermore, the SUR1 antagonist glibenclamide administered immediately after rAION injury provided no protection to proximal ON microvasculature 1 day post-injury but may reduce optic nerve head edema in a manner unrelated to ON SUR1 expression. Our results suggest that there may be fundamental differences between rAION optic nerve ischemia and other CNS white matter injuries where SUR1 appears to play a role.

  2. SUR1-Associated Mechanisms Are Not Involved in Ischemic Optic Neuropathy 1 Day Post-Injury.

    PubMed

    Nicholson, James D; Guo, Yan; Bernstein, Steven L

    2016-01-01

    Ischemia-reperfusion injury after central nervous system (CNS) injury presents a major health care challenge with few promising treatments. Recently, it has become possible to reduce edema after CNS injury by antagonizing a sulfonylurea receptor 1 (SUR1) regulated ion channel expressed after injury. SUR1 upregulation after injury is a necessary precondition for the formation of this channel, and has been implicated in white matter injury after clinical spinal cord trauma. Glibenclamide, an SUR1 antagonist, appears to have neuroprotective effect against cerebral stroke in an open-label small clinical trial and great effectiveness in reducing damage after varied experimental CNS injury models. Despite its importance in CNS injuries, SUR1 upregulation appears to play no part in rodent anterior ischemic optic neuropathy (rAION) injury as tested by real-time PCR and immunohistochemical staining of rAION-injured rat optic nerve (ON). Furthermore, the SUR1 antagonist glibenclamide administered immediately after rAION injury provided no protection to proximal ON microvasculature 1 day post-injury but may reduce optic nerve head edema in a manner unrelated to ON SUR1 expression. Our results suggest that there may be fundamental differences between rAION optic nerve ischemia and other CNS white matter injuries where SUR1 appears to play a role. PMID:27560494

  3. [Marine algae of Baja California Sur, Mexico: nutritional value].

    PubMed

    Carrillo Domínguez, Silvia; Casas Valdez, Margarita; Ramos Ramos, Felipe; Pérez-Gil, Fernando; Sánchez Rodríguez, Ignacio

    2002-12-01

    The Baja California Peninsula is one of the richest regions of seaweed resources in México. The objective of this study was to determine the chemical composition of some marine algae species of Baja California Sur, with an economical potential due to their abundance and distribution, and to promote their use as food for human consumption and animal feeding. The algae studied were Green (Ulva spp., Enteromorpha intestinalis, Caulerpa sertularoides, Bryopsis hypnoides), Red (Laurencia johnstonii, Spyridia filamentosa, Hypnea valentiae) and Brown (Sargassum herporizum, S. sinicola, Padina durvillaei, Hydroclathrus clathrathus, Colpomenia sinuosa). The algae were dried and ground before analysis. In general, the results showed that algae had a protein level less than 11%, except L. johnstonii with 18% and low energy content. The ether extract content was lower than 1%. However, the algae were a good source of carbohydrates and inorganic matter.

  4. [The family environment of children in France and Canada].

    PubMed

    Festy, P

    1994-01-01

    "Two fundamental changes have influenced family demographics in both France and Canada over the past 25 years: the rise in the number of births to unmarried parents and the rapid growth in the proportion of children separated from one parent or another before they reach adulthood. The impact of these changes on the family life of children must, however, be seen in perspective. Parents not married at the time of the child's birth nevertheless tend to live together. As well, the separation of birth parents allows for the formation of new families, giving the child a stepmother or stepfather and step-siblings. International or interregional comparisons give a further dimension to these phenomena; for example, Quebec, France and the rest of Canada rank in that order for the frequency of births outside marriage, while Quebec and the rest of Canada come ahead of France with a higher frequency of separations." (SUMMARY IN ENG AND SPA)

  5. Bilateral Pulmonary Embolism Following a Viper Envenomation in France

    PubMed Central

    Bart, Géraldine; Pineau, Samuel; Biron, Charlotte; Connault, Jérôme; Artifoni, Mathieu

    2016-01-01

    Abstract Complications following snake bites are not common in France. We report the case of a bilateral pulmonary embolism following a viper envenomation in France. A healthy 72-year-old female presented with a lower limb hematoma following a viper bite. She was admitted at the hospital 2 days later and received low-molecular-weight heparin because of bed rest. Seven days later, she complained of thoracic pain and respiratory failure, and a bilateral pulmonary was diagnosed, without biological sign of neither disseminated intravascular coagulation nor coagulation trouble. Repeated lower limbs Doppler ultrasound were normal. This case is particularly interesting because it is only the 7th reported case of pulmonary embolism following a snake envenomation; moreover, it happened in France where poisonous snakes are very rare. Several hypotheses have been made to explain this late localized coagulopathy: an increased level of unstable fibrin produced by thrombin-like glycoproteins from the venom is one of them. PMID:27175626

  6. Bat Rabies in France: A 24-Year Retrospective Epidemiological Study

    PubMed Central

    Picard-Meyer, Evelyne; Robardet, Emmanuelle; Arthur, Laurent; Larcher, Gérald; Harbusch, Christine; Servat, Alexandre; Cliquet, Florence

    2014-01-01

    Since bat rabies surveillance was first implemented in France in 1989, 48 autochthonous rabies cases without human contamination have been reported using routine diagnosis methods. In this retrospective study, data on bats submitted for rabies testing were analysed in order to better understand the epidemiology of EBLV-1 in bats in France and to investigate some epidemiological trends. Of the 3176 bats submitted for rabies diagnosis from 1989 to 2013, 1.96% (48/2447 analysed) were diagnosed positive. Among the twelve recognised virus species within the Lyssavirus genus, two species were isolated in France. 47 positive bats were morphologically identified as Eptesicus serotinus and were shown to be infected by both the EBLV-1a and the EBLV-1b lineages. Isolation of BBLV in Myotis nattereri was reported once in the north-east of France in 2012. The phylogenetic characterisation of all 47 French EBLV-1 isolates sampled between 1989 and 2013 and the French BBLV sample against 21 referenced partial nucleoprotein sequences confirmed the low genetic diversity of EBLV-1 despite its extensive geographical range. Statistical analysis performed on the serotine bat data collected from 1989 to 2013 showed seasonal variation of rabies occurrence with a significantly higher proportion of positive samples detected during the autumn compared to the spring and the summer period (34% of positive bats detected in autumn, 15% in summer, 13% in spring and 12% in winter). In this study, we have provided the details of the geographical distribution of EBLV-1a in the south-west of France and the north-south division of EBLV-1b with its subdivisions into three phylogenetic groups: group B1 in the north-west, group B2 in the centre and group B3 in the north-east of France. PMID:24892287

  7. The analysis of a World War I U.S. service member's dental remains recovered in France.

    PubMed

    Shiroma, Calvin Y

    2014-11-01

    In October 2009, the grave of an unknown World War I (WWI) U.S. service member was exhumed in Rembercourt-Sur-Mad Village, in the Lorraine Region of France. The skeletal remains and material evidence were accessioned into the Joint POW/MIA Accounting Command's (JPAC) Central Identification Laboratory (CIL). The personnel records for the associated casualty were requested, received, and reviewed. A dental profile was present among the service member's personal information. There were multiple points of concordance between the dental records of the associated casualty, and the recovered dental remains to include eight restored teeth, 15 unrestored teeth, and three antemortem missing teeth. Distinctive restorations which compared favorably included a porcelain crown and multiple gold foil fillings. All lines of evidence (historical, material evidence/personal effects, anthropological, and dental) and the circumstances of loss compared positively with the associated casualty. On April 1, 2010, the previously unaccounted-for U.S. service member was positively identified and on June 23, 2010, was buried with full military honors at Arlington National Cemetery. PMID:25060333

  8. The analysis of a World War I U.S. service member's dental remains recovered in France.

    PubMed

    Shiroma, Calvin Y

    2014-11-01

    In October 2009, the grave of an unknown World War I (WWI) U.S. service member was exhumed in Rembercourt-Sur-Mad Village, in the Lorraine Region of France. The skeletal remains and material evidence were accessioned into the Joint POW/MIA Accounting Command's (JPAC) Central Identification Laboratory (CIL). The personnel records for the associated casualty were requested, received, and reviewed. A dental profile was present among the service member's personal information. There were multiple points of concordance between the dental records of the associated casualty, and the recovered dental remains to include eight restored teeth, 15 unrestored teeth, and three antemortem missing teeth. Distinctive restorations which compared favorably included a porcelain crown and multiple gold foil fillings. All lines of evidence (historical, material evidence/personal effects, anthropological, and dental) and the circumstances of loss compared positively with the associated casualty. On April 1, 2010, the previously unaccounted-for U.S. service member was positively identified and on June 23, 2010, was buried with full military honors at Arlington National Cemetery.

  9. Information and communication technology: models of evaluation in France.

    PubMed

    Baron, Georges-Louis; Bruillard, Eric

    2003-05-01

    This paper aims at analyzing the evaluation of information and communication technology (ICT) in educational settings in France. First, it focuses on some characteristics of the French educational system and analyzes the trend towards a more decentralized management of education, which raises several important issues, including the trend for central evaluation to evolve from control to communication. Secondly, we define our view of ICT and evaluation. Then we present an overview of evaluation at the national level and European level and discuss some of the main research approaches in France concerning students' learning, learning instruments, and teachers' communities. Finally, some perspectives for the future of ICT evaluation are proposed. PMID:24011486

  10. [Probable flora: an expression mean of ecological gradients in France].

    PubMed

    Garbolino, Emmanuel; De Ruffray, Patrice; Brisse, Henry; Grandjouan, Gilles

    2013-02-01

    The application of the criterion of fidelity of plants to plants over four millions botanical observations in France is considered to characterize the ecology of 215,000 phytosociological surveys. Among those discriminant plants, some are missing of the surveys, but they can have a certain probability of occurrence: these plants are called "probable plants" and they represent the "probable flora" of a territory. The study of their geographical distribution shows ecological gradients of flora across France in a better way than only considering the botanical observations. In fact, this method mitigates the discontinuities of taxa observations whose absence may be due to historical and/or anthropogenic factors.

  11. 46 CFR 7.135 - Point Sur, CA to Cape Blanco, OR.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... shore. (e) A line drawn from the northwestern tip of Tomales Point to latitude 38°15.1′ N. longitude 123... 46 Shipping 1 2014-10-01 2014-10-01 false Point Sur, CA to Cape Blanco, OR. 7.135 Section 7.135... Pacific Coast § 7.135 Point Sur, CA to Cape Blanco, OR. (a) A line drawn from Monterey Harbor Light “6”...

  12. 46 CFR 7.135 - Point Sur, CA to Cape Blanco, OR.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... shore. (e) A line drawn from the northwestern tip of Tomales Point to latitude 38°15.1′ N. longitude 123... 46 Shipping 1 2012-10-01 2012-10-01 false Point Sur, CA to Cape Blanco, OR. 7.135 Section 7.135... Pacific Coast § 7.135 Point Sur, CA to Cape Blanco, OR. (a) A line drawn from Monterey Harbor Light “6”...

  13. 46 CFR 7.135 - Point Sur, CA to Cape Blanco, OR.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... shore. (e) A line drawn from the northwestern tip of Tomales Point to latitude 38°15.1′ N. longitude 123... 46 Shipping 1 2011-10-01 2011-10-01 false Point Sur, CA to Cape Blanco, OR. 7.135 Section 7.135... Pacific Coast § 7.135 Point Sur, CA to Cape Blanco, OR. (a) A line drawn from Monterey Harbor Light “6”...

  14. 46 CFR 7.135 - Point Sur, CA to Cape Blanco, OR.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... shore. (e) A line drawn from the northwestern tip of Tomales Point to latitude 38°15.1′ N. longitude 123... 46 Shipping 1 2013-10-01 2013-10-01 false Point Sur, CA to Cape Blanco, OR. 7.135 Section 7.135... Pacific Coast § 7.135 Point Sur, CA to Cape Blanco, OR. (a) A line drawn from Monterey Harbor Light “6”...

  15. 46 CFR 7.130 - Point Conception, CA to Point Sur, CA.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Point Conception, CA to Point Sur, CA. 7.130 Section 7.130 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Pacific Coast § 7.130 Point Conception, CA to Point Sur, CA. (a) A line drawn from the southernmost extremity of Fossil Point at longitude...

  16. 46 CFR 7.135 - Point Sur, CA to Cape Blanco, OR.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Point Sur, CA to Cape Blanco, OR. 7.135 Section 7.135 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Pacific Coast § 7.135 Point Sur, CA to Cape Blanco, OR. (a) A line drawn from Monterey Harbor Light “6” to latitude 36°36.5′ N. longitude...

  17. Modelisations des effets de surface sur les jets horizontaux subsoniques d'hydrogene et de methane

    NASA Astrophysics Data System (ADS)

    Gomez, Luis Fernando

    Le developpement des codes et de normes bases sur une methodologie scientifique requiert la capacite de predire l'etendue inflammable de deversements gazeux d'hydrogene sous differentes conditions. Des etudes anterieures ont deja etabli des modeles bases sur les lois de conservation de la mecanique des fluides basees sur des correlations experimentales qui permettent de predire la decroissance de la concentration et de la vitesse d'un gaz le long de l'axe d'un jet libre vertical. Cette etude s'interesse aux effets de proximite a une surface horizontale parallele sur un jet turbulent. Nous nous interessons a son impact sur l'etendue du champ de la concentration et sur l'enveloppe inflammable en particulier. Cette etude est comparative : l'hydrogene est compare au methane. Ceci permet de degager l'influence des effets de difference de la densite sur le comportement du jet, et de comparer le comportement de l'hydrogene aux correlations experimentales, qui ont ete essentiellement etablies pour le methane. Un modele decrivant l'evolution spatio-temporelle du champ de concentration du gaz dilue est propose, base sur la mecanique des fluides computationnelle. Cette approche permet de varier systematiquement les conditions aux frontieres (proximite du jet a la surface, par exemple) et de connaitre en detail les proprietes de l'ecoulement. Le modele est implemente dans le code de simulations par volumes finis de FLUENT. Les resultats des simulations sont compares avec les lois de similitudes decoulant de la theorie des jets d'ecoulements turbulents libres ainsi qu'avec les resultats experimentaux disponibles. L'effet de la difference des masses molaires des constituantes du jet et des constituantes du milieu de dispersion est egalement etudie dans le contexte du comportement d'echelle de la region developpee du jet.

  18. France's Administrative Tertiary: Stable Numbers for Occupations in Flux.

    ERIC Educational Resources Information Center

    Liaroutzos, Olivier; Meriot, Sylvie-Anne

    1995-01-01

    During the past decade, the number of jobs in France's administrative service sector has remained stable. General administrative work has become more infrequent; however, the basic occupations of secretary and accountancy have been maintained. Although the number of typists has declined, the number of "secretarial" jobs has increased dramatically.…

  19. 78 FR 34960 - Airworthiness Directives; Eurocopter France Model Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-11

    ... a ``significant rule'' under the DOT Regulatory Policies and Procedures (44 FR 11034, February 26... Federal Aviation Administration 14 CFR Part 39 RIN 2120-AA64 Airworthiness Directives; Eurocopter France... rulemaking (NPRM). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter...

  20. 77 FR 54353 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-05

    ... 77 FR 20319, the Federal Register published our notice of proposed rulemaking (NPRM), which proposed...'' under DOT Regulatory Policies and Procedures (44 FR 11034, February 26, 1979); (3) Will not affect...-17165; AD 2012-17-02] RIN 2120-AA64 Airworthiness Directives; Eurocopter France Helicopters...

  1. 78 FR 59298 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-26

    ...--16847 (76 FR 70046, November 10, 2011), and adding the following new AD: Eurocopter France: Docket No...-05, Amendment 39-16847 (76 FR 70046, November 10, 2011) for Eurocopter Model AS350B, B1, B2, B3, BA... helicopter. Actions Since AD 2011-22-05 Was Issued Since we issued AD 2011-22-05 (76 FR 70046, November...

  2. Teaching of Languages to Migrant Workers . (Toulouse, France).

    ERIC Educational Resources Information Center

    Buscail, X.; And Others

    With the cooperation of the Council of Europe, CREPT (tr. Regional Center for the Study and Promotion of Travel) conducted an experimental training course for migrant workers at Toulouse, France. Aim of the course was to bring trainees from the stage of attaining literacy to that of entering the Centre for Vocational Training for Adults (FPA). In…

  3. Ecole Maternelle (Preschool) in France: A Cross-Cultural Perspective

    ERIC Educational Resources Information Center

    Brougere, Gilles; Guenif-Souilamas, Nacira; Rayna, Sylvie

    2008-01-01

    This article looks at a cross-cultural analysis of interviews of (im/migrant and non-im/migrant) preschool teachers and parents, concerning im/migrant children enrolled in the French "ecole maternelle", in the context of the international Children Crossing Borders (CCB) research project. Interviews were conducted in France following a polyphonic…

  4. International Reports on Literacy Research: France, United Kingdom, Brazil

    ERIC Educational Resources Information Center

    Malloy, Jacquelynn A., Comp.; Botza, Stergios, Comp.

    2005-01-01

    This is a compilation of reports on international literacy research. The report includes 3 separate reports on France, United Kingdom and Brazil. In the first report, research correspondent Jacques Fijalkow presents research into variations of reading motivation related to students' socioeconomic status (SES), age, and gender. Three of these…

  5. International Reports on Literacy Research: Argentina, Mexico, France

    ERIC Educational Resources Information Center

    Malloy, Jacquelynn A., Comp.; Mallozzi, Christine, Comp.

    2007-01-01

    This is a compilation of reports on international literacy research. The report includes 3 separate reports on Argentina, Mexico, and France. In the first report, Melina Porto reports on a new implementation of a teacher-education program currently underway in the province of Buenos Aires, Argentina, under the leadership of teacher-researcher…

  6. Changing Patterns of Educational Accountability in England and France.

    ERIC Educational Resources Information Center

    Broadfoot, Patricia

    1985-01-01

    Uses France and England--because of their radically different institutional and ideological traditions in education--to illustrate common trends in educational accountability. Explains general trends affecting advanced capitalist societies at the present time, e.g., the use of corporate management approaches in education and the adoption of…

  7. Report of the first Vagococcus lutrae human infection, Marseille, France

    PubMed Central

    Garcia, V.; Abat, C.; Rolain, J.-M.

    2015-01-01

    Vagococcus lutrae is a Gram-positive coccus initially isolated from the common otter (Lutra lutra) but that has never been reported as a human pathogen. We describe the first case of human infection due to Vagococcus lutrae in Marseille, France. PMID:26862437

  8. Frances Kellor, Americanization, and the Quest for Participatory Democracy

    ERIC Educational Resources Information Center

    Press, John

    2010-01-01

    Frances Alice Kellor (1873 - 1952) is most famous for leading the Americanization movement that greeted immigrants from 1906 to 1921. The movement has been damned as coercive in the name of conformity in the historical literature. This dissertation argues that Kellor's Americanization movement promoted immigrants and immigration, Americanized…

  9. Fine-scale human genetic structure in Western France

    PubMed Central

    Karakachoff, Matilde; Duforet-Frebourg, Nicolas; Simonet, Floriane; Le Scouarnec, Solena; Pellen, Nadine; Lecointe, Simon; Charpentier, Eric; Gros, Françoise; Cauchi, Stéphane; Froguel, Philippe; Copin, Nane; Balkau, B; Ducimetière, P; Eschwège;, E; Alhenc-Gelas, F; Girault, A; Fumeron, F; Marre, M; Roussel, R; Bonnet, F; Cauchi, S; Froguel, P; Cogneau, J; Born, C; Caces, E; Cailleau, M; Lantieri, O; Moreau, J G; Rakotozafy, F; Tichet, J; Le Tourneau, Thierry; Probst, Vincent; Le Marec, Hervé; Molinaro, Sabrina; Balkau, Beverley; Redon, Richard; Schott, Jean-Jacques; Blum, Michael GB; Dina, Christian

    2015-01-01

    The difficulties arising from association analysis with rare variants underline the importance of suitable reference population cohorts, which integrate detailed spatial information. We analyzed a sample of 1684 individuals from Western France, who were genotyped at genome-wide level, from two cohorts D.E.S.I.R and CavsGen. We found that fine-scale population structure occurs at the scale of Western France, with distinct admixture proportions for individuals originating from the Brittany Region and the Vendée Department. Genetic differentiation increases with distance at a high rate in these two parts of Northwestern France and linkage disequilibrium is higher in Brittany suggesting a lower effective population size. When looking for genomic regions informative about Breton origin, we found two prominent associated regions that include the lactase region and the HLA complex. For both the lactase and the HLA regions, there is a low differentiation between Bretons and Irish, and this is also found at the genome-wide level. At a more refined scale, and within the Pays de la Loire Region, we also found evidence of fine-scale population structure, although principal component analysis showed that individuals from different departments cannot be confidently discriminated. Because of the evidence for fine-scale genetic structure in Western France, we anticipate that rare and geographically localized variants will be identified in future full-sequence analyses. PMID:25182131

  10. [Courses in microsurgical techniques in France and abroad].

    PubMed

    Alzakri, A; Al-Rajeh, M; Liverneaux, P A; Facca, S

    2014-06-01

    The objective of this work was to determine the state of current training programs for microsurgery in France and abroad. Our survey of microsurgery training programs determined the registration volume, program contents, and number of students in France, and looked at registration volume and teaching time for programs abroad. Data were obtained from the Internet, university administration, those responsible for university diploma programs, and students. There were 18 university diploma programs in microsurgery in France. The average list price was €1,129 for an average of 19 hours of theoretical training and 100 hours of practice. Evaluation methods varied, but all required at least vascular anastomosis in rats. In 2011-2012, 148 students were enrolled and 126 graduated (85% passing rate). Abroad, 16 basic courses were listed in the USA, Europe and Asia. Nine advanced courses were offered. The average price was $1,346 for 36 hours of practice in the basic courses and $1,955 for over 50 hours of training in advanced courses. None of these courses gave out a diploma. Our results show that in France, university diploma programs in microsurgery are heterogeneous and the French College should consider updating them. Globally, a study is underway by the International Microsurgical Simulation Society.

  11. Henry Hudson Monument, seen from Frances Schervier Apartments, with Henry ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Henry Hudson Monument, seen from Frances Schervier Apartments, with Henry Hudson Bridge, Inwood Hill Park, Manhattan skyline, and George Washington Bridge in background, looking southwest. - Henry Hudson Parkway, Extending 11.2 miles from West 72nd Street to Bronx-Westchester border, New York County, NY

  12. Henry Hudson Monument, seen from Frances Schervier Apartments, with Henry ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Henry Hudson Monument, seen from Frances Schervier Apartments, with Henry Hudson Bridge, Inwood Hill Park, Manhattan skyline, George Washington Bridge, Hudson River, and Palisades Interstate Park in background, looking south. - Henry Hudson Parkway, Extending 11.2 miles from West 72nd Street to Bronx-Westchester border, New York County, NY

  13. Wildlife Reservoir for Hepatitis E Virus, Southwestern France

    PubMed Central

    Lhomme, Sebastien; Top, Sokunthea; Bertagnoli, Stephane; Dubois, Martine; Guerin, Jean-Luc

    2015-01-01

    Pigs are a reservoir for hepatitis E virus (HEV). To determine the relative contribution of game to the risk for human HEV infection in southwestern France, we tested wildlife samples. HEV RNA was in 3.3% of wildlife livers, indicating that in this region, eating game meat is as risky as eating pork. PMID:26079541

  14. 77 FR 44118 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-27

    ... Order 12866; 2. Is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034... Helicopters AGENCY: Federal Aviation Administration (FAA), Department of Transportation (DOT). ACTION: Final... France (Eurocopter) Model EC155B1 helicopters with a certain automated flight control system...

  15. Critical Citizenship Education in England and France: A Comparative Analysis

    ERIC Educational Resources Information Center

    Johnson, Laura; Morris, Paul

    2012-01-01

    The promotion of "critical citizenship" has become a key objective of official school curricula around the world. Using an analytic framework developed by the authors, this paper identifies the diverse conceptions of critical citizenship that are promoted, by comparing the official school curricula for citizenship in England and France. The…

  16. Promoting Reflective Practice in Continuing Education in France

    ERIC Educational Resources Information Center

    Ryder, Jane

    2012-01-01

    Educationalist Fred Korthagen elaborated a model in the 1980s for the relationship between the teacher educator and the teacher which embraces reflective practice as its guiding principle. In the present study, research was carried out into teacher development among a small group of language teachers working in continuing education in France.…

  17. Psychology and Didactics of Mathematics in France--An Overview.

    ERIC Educational Resources Information Center

    Vergnaud, Gerard

    1983-01-01

    Examples are given of the variety of mathematical concepts and problems being studied by psychologically oriented researchers in France. Work on decimals, circles, natural numbers, decimal and real numbers, and didactic transposition are included. Comments on designing research on mathematics concept formation conclude the article. (MNS)

  18. Sea surface temperature of the coastal zones of France

    NASA Technical Reports Server (NTRS)

    Deschamps, P. Y.; Verger, F.; Monget, J. M.; Crepon, M. (Principal Investigator); Frouin, R.; Cassanet, J.; Wald, L.

    1980-01-01

    The results of an investigation to map the various thermal gradients in the coastal zones of France are presented. Paricular emphasis is given to the natural phenomena and man made thermal effluents. It is shown that a close correlation exist between wind speed direction and the offshore width of the effluent.

  19. Location of robotic surgical systems worldwide and in France.

    PubMed

    Vaessen, C

    2011-10-01

    The advent of robot-assisted surgery is a surgical revolution. However, the costs of installing and using a da Vinci system are impediments to the proliferation of this technology. This article reviews the locations of robotic surgical systems worldwide and in France, in 2010.

  20. Recent Developments in Assessment and Examination Procedures in France.

    ERIC Educational Resources Information Center

    Broadfoot, Patricia

    Recent changes in educational assessment in France reflect pressures to modernize the French educational system to align it with prevailing democratic and egalitarian values and to respond to the economy's vocational training needs. After providing background on the French educational system, this paper discusses two areas of secondary school…

  1. Adolescents and Smoking: Evidence from France and Spain.

    ERIC Educational Resources Information Center

    Bosanquet, Nick; Magee, Jayne

    1999-01-01

    Focuses on recent evidence now available from France and Spain on the smoking behavior of adolescents and young people. Evidence indicates that it will be a massive challenge to reduce smoking among young people. Argues that public awareness of the threat to health from smoking should be raised and that public health measures require further…

  2. 78 FR 37156 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-20

    ... Federal Aviation Administration 14 CFR Part 39 RIN 2120-AA64 Airworthiness Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of proposed rulemaking (NPRM... file in the docket all comments that we receive, as well as a report summarizing each...

  3. Teacher Training in France in the Early 2010s

    ERIC Educational Resources Information Center

    Lapostolle, Guy; Chevaillier, Thierry

    2011-01-01

    The organisation of teacher training was thoroughly transformed in France in 2010. This transformation was the consequence of three interrelated reforms: the requirement of a Master's degree for all teachers, the new recruitment process for teachers and the integration of teacher training colleges (IUFM) into the universities. Universities are now…

  4. 'Miss Frances', 'Miss Gail' and 'Miss Sandra' Crapemyrtles

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The Agricultural Research Service, United States Department of Agriculture, announces the release to nurserymen of three new crapemyrtle cultivars named 'Miss Gail', 'Miss Frances', and 'Miss Sandra'. ‘Miss Gail’ resulted from a cross-pollination between ‘Catawba’ as the female parent and ‘Arapaho’ ...

  5. [The pharmaceutical industry in France: the turning point of 1915].

    PubMed

    Bonnemain, Bruno

    2015-12-01

    For several convergent reasons, 1915 was a key period for the pharmaceutical industry in France. The overall realization that France was dependent on Germany for chemical and pharmaceutical products came from shortages of key drugs but also from massive use of poison gas for which France was not able to face this unexpected event. France's shortage for chemists properly trained to answer the needs of industry, the weak relationship between industry and faculty, the uncomfortable situation of specialty drugs, the regulations on patents and trademarks were many subjects of controversies which will contribute to the analysis of the source of this French dependence to Germany. It will be at the origin of new orientations after the war for the pharmaceutical industry and the French society. The objective was to be independent for drugs and consequently to resolve the identified issues, as well as to have a dynamic industrial research. The creation and development of several pharmaceutical companies after the war was a more or less direct benefit from the considerations starting in 1915.

  6. Who Studies Abroad? Evidence from France and Italy

    ERIC Educational Resources Information Center

    Di Pietro, Giorgio; Page, Lionel

    2008-01-01

    This article uses data from representative samples of university students in France and Italy in an attempt to investigate the determinants of participation in foreign exchange programmes. Empirical results indicate that selection into these programmes is mainly driven by student's academic and foreign language skills. On the other hand, parents'…

  7. School Design and Management: Three Examples from France.

    ERIC Educational Resources Information Center

    Alt, Patrick

    2001-01-01

    Presents three examples of large-scale school construction and renovation projects in France where a link has been established between school design and successful teaching and learning. Further discussed are the conclusions that can be drawn from these projects in preparatory work prior to building. (GR)

  8. Identification Strategies of a Texas Rebel: Frances (Sissy) Farenthold.

    ERIC Educational Resources Information Center

    McMahan, Eva M.

    The identification techniques in Herbert C. Kelman's schema of identification were used to analyze the near, and perhaps surprising, success of Rep. Frances (Sissy) Farenthold's bid for the Democratic Texas gubernatorial nomination in 1972. Opposing government corruption, Farenthold overcame the potential obstacles of being a politically liberal…

  9. Migration and Marginality: Guestworkers in Germany and France.

    ERIC Educational Resources Information Center

    Rist, Ray C.

    1979-01-01

    Examines migratory movements in Europe since 1954, with particular emphasis on the 13 to 14 million immigrants to the industrial countries of northern Europe. Concludes that the movement of manpower has been critical in sustaining the post-World War II economies of industrialized nations such as Germany and France. (Author/DB)

  10. Proceedings of the Full Board Meeting (Orleans, France, July 1971).

    ERIC Educational Resources Information Center

    International Council of Scientific Unions, Paris (France). Abstracting Board.

    The 1971 General Assembly and full board meetings of the International Council of Scientific Unions Abstracting Board (ICSU AB) were held in July at Orleans, France. This volume is the published proceedings of those meetings. The first part of the Proceedings is a detailed description of the activities of the Board. The second part records the…

  11. White-nose syndrome fungus (Geomyces destructans) in bat, France.

    PubMed

    Puechmaille, Sebastien J; Verdeyroux, Pascal; Fuller, Hubert; Gouilh, Meriadeg Ar; Bekaert, Michael; Teeling, Emma C

    2010-02-01

    White-nose syndrome is caused by the fungus Geomyces destructans and is responsible for the deaths of >1,000,000 bats since 2006. This disease and fungus had been restricted to the northeastern United States. We detected this fungus in a bat in France and assessed the implications of this finding. PMID:20113562

  12. France's grandes écoles accused of elitism

    NASA Astrophysics Data System (ADS)

    Hellemans, Alexander

    2010-02-01

    Physicists in France have backed government plans to open up the country's elite grandes écoles to more students from poorer backgrounds. The government wants to allow up to 30% of students to be given free scholarships in an attempt to broaden the social mix of the student body. The physicists say this would not lead to a lowering of standards.

  13. International Reports on Literacy Research: Canada, France, Russia

    ERIC Educational Resources Information Center

    Malloy, Jacquelynn A., Comp.; Botzakis, Stergios, Comp.

    2006-01-01

    This article is a compilation of reports on international literacy research. The report includes 3 separate reports on Canada, France and Russia. In the first report, research correspondent Linda M. Phillips, in collaboration with Christian Beaulieu, reports on the Canadian Language and Literacy Research Network (CLLRNet). The vision of CLLRNet is…

  14. Romanticism or Reality? An Exploration of Frances Mary Hendry's "Chandra."

    ERIC Educational Resources Information Center

    Johnson, Jilaine

    This paper singles out a novel written for children about India, "Chandra" (1995) by Frances Mary Hendry, as a powerful and useful novel to present to today's 11 to 14 year old students. The paper contends that the novel allows students to explore and consider different value systems, challenges them to become aware of prejudice and the making of…

  15. Foodborne outbreak and nonmotile Salmonella enterica variant, France.

    PubMed

    Le Hello, Simon; Brisabois, Anne; Accou-Demartin, Marie; Josse, Adeline; Marault, Muriel; Francart, Sylvie; Da Silva, Nathalie Jourdan; Weill, François-Xavier

    2012-01-01

    We report a food-related outbreak of salmonellosis in humans caused by a nonmotile variant of Salmonella enterica serotype Typhimurium in France in 2009. This nonmotile variant had been circulating in laying hens but was not considered as Typhimurium and consequently escaped European poultry flock regulations.

  16. Correspondence Tuition in France and the Development of Permanent Education.

    ERIC Educational Resources Information Center

    Cros, Louis

    This report covers the current situation and general trends in correspondence study in France and describes two public institutions involved in it: Centre National de Tele-Enseignement and Radio-Television Scolaire. The evolution of correspondence study has been linked with the development of permanent education and the parallel transformation of…

  17. Infection with Mycobacterium microti in Animals in France

    PubMed Central

    Michelet, Lorraine; de Cruz, Krystel; Zanella, Gina; Aaziz, Rachid; Bulach, Tabatha; Karoui, Claudine; Hénault, Sylvie; Joncour, Guy

    2014-01-01

    We describe here 35 animal cases of tuberculosis due to Mycobacterium microti in France (2002–2014). Recently, molecular tools that overcome the difficulty of confirming infection by this potentially zoonotic agent have revealed an increasing number of cases, suggesting that its prevalence may have been underestimated. PMID:25540404

  18. Citrobacter amalonaticus human urinary tract infections, Marseille, France.

    PubMed

    Garcia, V; Abat, C; Moal, V; Rolain, J-M

    2016-05-01

    Citrobacter amalonaticus is a bacterium that has rarely been reported as a human pathogen. Here we report four cases of C. amalonaticus infections occurring in patients hospitalized in Marseille, France, and review all cases described in the published literature.

  19. "Training the Trainers" of Teachers in France: Assessment and Outlook

    ERIC Educational Resources Information Center

    Lapostolle, Guy

    2009-01-01

    With the creation of IUFMs (university institutes of teacher training) in the 1990s, the training of teacher trainers in France has become a fundamental part of the renewal of teacher training. It is seen as a fundamental lever for the IUFMs to achieve the tasks and goals entrusted to them: training teachers who need to accommodate the new demands…

  20. Carcinome hépatocellulaire non fibrolamellaire sur foie sain

    PubMed Central

    Bouomrani, Salem; Kilani, Ichrak; Nouma, Hanène; Slama, Alaeddine; Beji, Maher

    2014-01-01

    Le carcinome hépatocellulaire (CHC) survient le plus souvent sur foie de cirrhose. Sa survenue sur un foie sain est exceptionnelle et pose un véritable défit diagnostique pour le clinicien. Nous rapportons l'observation d'un patient de 53 ans, sans antécédents pathologiques notables qui fût admis pour exploration d'une douleur de l'hypochondre droit évoluant depuis quelques mois avec une exacerbation récente, associée à un amaigrissement important et une altération de l’état général. L'examen clinique notait une hépatomégalie ferme et douloureuse. L’échographie abdominale montrait une masse hétérogène du secteur latéral droit du foie faisant 10 cm de grand axe. La TDM abdominale montrait une masse tissulaire, hétérogène, à vascularisation artérielle importante, mesurant 10 cm de diamètre et occupant le secteur latéral droit du foie. Cette tumeur comprime la branche portale droite sans signes d'extension. Il n'y avait pas d'adénopathie ni d’épanchement intra abdominal. La ponction biopsique écho-guidée avait conclu à un CHC non fibrolamellaire. Le bilan biologique, en particulier les transaminases, le taux de prothrombine, l’électrophorèse des protéines sanguine et l'alpha foeto-protéine, était sans anomalies. Les sérologies de l'hépatites virales B et C ainsi que la recherche des auto anticorps spécifiques des hépatites auto immunes et le bilan cuprique étaient aussi négatives. Vue l’âge, le stade avancé de la tumeur et l'altération de l’état général la conduite thérapeutique était de s'abstenir. PMID:25419293

  1. IAU Colloquium on UV and X-ray Spectroscopy of Astrophysical and Laboratory Plasmas, 102nd, Beaulieu-sur-Mer, France, Sept. 9-11, 1987, Proceedings

    NASA Astrophysics Data System (ADS)

    Bely-Dubau, F.; Faucher, P.

    1988-03-01

    The present conference discusses the solar physics results of Spacelab 2, spectroscopic methods for electron density determination, microcalorimeters for X-ray spectroscopy, spectral observations of the XUV astronomical background radiation, XUV lasers, spectroscopic diagnoses of tokamaks, nonthermal X-ray spectra from a tokamak, and space- and time-resolved plasma diagnostics in laser-produced plasmas. Also discussed are the application in atomic physics of coupled differential equations, the interpretation of unresolved hyperfine and/or Zeeman structures in stellar spectra, atomic physics for hot plasmas, IUE satellite-based UV astronomy contributions, plasma shifts of ion lines, and the use of Ti, Si, C, Be, and LiF in soft X-ray optics.

  2. SPS 91 - Power from space; Proceedings of the 2nd International Symposium, Ecole Superieure d'Electricite, Gif-sur-Yvette, France, Aug. 27-30, 1991

    NASA Astrophysics Data System (ADS)

    Various papers on the concept of Solar Power Satellites (SPS) are presented. The general topics addressed include: global energy issues; SPS demonstration projects; extraterrestrial materials; power generation, conversion, and storage; environmental issues; development strategies.

  3. Effets de la formation sur la violence conjugale

    PubMed Central

    Zaher, Eman; Keogh, Kelly; Ratnapalan, Savithiri

    2014-01-01

    Résumé Objectif Décrire et évaluer l’efficacité de la formation concernant la violence conjugale pour améliorer les connaissances et permettre la reconnaissance et la prise en charge par les médecins des femmes victimes de violence. Sources des données On a fait une recension dans la base de données des révisions systématiques de Cochrane, MEDLINE, PubMed, PsycINFO, ERIC et EMBASE pour trouver des articles publiés entre le 1e janvier 2000 et le 1e novembre 2012. Des recherches manuelles ont complété cette recension pour cerner des articles pertinents à l’aide d’une stratégie de recherche combinant des textes, mots et expressions MeSH. Sélection des études On a choisi des études randomisées contrôlées qui portaient sur des interventions éducatives à l’intention des médecins et fournissaient des données sur les effets des interventions. Synthèse On a inclus 9 études randomisées contrôlées qui décrivaient différentes approches pédagogiques et diverses mesures des résultats. Trois études examinaient les effets d’interventions éducatives pour des médecins en formation postdoctorale et ont constaté une augmentation des connaissances, mais il n’y a eu aucun changement dans le comportement en ce qui a trait à l’identification des victimes de violence conjugale. Six études portaient sur des interventions éducatives pour des médecins en pratique active. Trois d’entre elles utilisaient une approche à multiples facettes pour les médecins, qui combinait une formation ainsi que des interventions de soutien de la part du système pour changer les comportements des médecins, comme une sensibilisation générale accrue à la violence conjugale au moyen de brochures et d’affiches, des aide-mémoire pour rappeler aux médecins comment identifier les victimes, des moyens pour faciliter l’accès des médecins à des services de soutien pour les victimes, la réalisation d’audits et la fourniture de rétroaction. Les

  4. Sur Lago area, Venezuela: Three dimensional integrated seismic interpretation

    SciTech Connect

    Growcott, A.; McIan, A.; Ramirez, R. )

    1993-02-01

    In 1988, 550 square km of 3D seismic data were acquired in the Sur Del Lago area. The aims of the survey were (1) To better define structures already identified from the existing 1 [times] 1 km 2D seismic grid at the level of potential Cretaceous limestone reservoirs and (2) To further study the prospectivity of potential structural and stratigraphic traps within the Tertiary section. Detailed interpretation of the 3D survey using an interactive workstation led to an improved structural definition at the Cogollo limestone level and the identification of fault related inversion lineaments and basement related Cretaceous limestone structures. Based upon the new seismic interpretation a 4 well exploration project was planned. The new program commenced with the drilling of exploration well SLA-7-IX in 1991 which proved commercial amounts of hydrocarbons in the western part of the area. Detailed information collected from the exploration wells includes a comprehensive electric log suite, ditch cuttings and vertical seismic profiles. The information is being used as detailed lithological, stratigraphic and seismic data input for velocity modeling, ray trace modeling, seismic attribute analysis, and reservoir characterization software in order to further understand the structural and stratigraphic potential of the area.

  5. Field experiments of beach scarp erosion during oblique wave, stormy conditions (Normandy, France)

    NASA Astrophysics Data System (ADS)

    Bonte, Yoann; Levoy, Franck

    2015-05-01

    A field-based experimental study of beach scarp morphodynamic evolution was conducted on the shoreface of a macrotidal sandy beach subject to storms combined with spring tide events (Luc-sur-Mer, France). Both video and in-situ measurements on an artificial berm are used to understand beach scarp evolution over one tide during stormy conditions. Image time stacks are used to analyze the swash action on the beach scarp and topographical data of the scarp are recorded with a terrestrial scanner laser to quantify the morphodynamic response of the beach scarp to wave action. This work provides a new and unique dataset about beach scarp changes and berm morphology in particular under rising tide and oblique wind-wave conditions. During one stormy event, the berm was completely destroyed. However, contrasting alongshore changes were measured during the erosive phase with different crest and foot scarp retreats and eroded volumes between the west and the east side of the berm. The beach in front of the scarp also shows a contrasting residual evolution, indicating an evident longshore sediment transport on the study area as a consequence of incident oblique wave conditions. A strong connection between beach evolution and beach scarp changes is clearly identified. The scarp erosion increases on the west side of the berm when the beach level is lowered and reduces when the beach surface rises on the east side. The beach slope and foreshore elevation as a result of a longshore sediment transport between east and west profiles, influence swash activity. Overall, water depth and swash activity became progressively different along the scarp during the experiment. Swash measurements indicate that the presence of the beach scarp strongly influences the swash motion. At high tide, the reflection of the uprush on the scarp front induces a collision between the reflected backwash and the following uprush dynamic. These collisions reduce and sometimes stop the motion of the following

  6. [Reflection on the psychiatric financial allocation in France].

    PubMed

    Boyer, L; Fond, G; Devictor, B; Samuelian, J-C; Lancon, C; Rouillon, F; Gaillard, R; Zendjidjian, X; Llorca, P-M

    2016-08-01

    For 25years work has been underway in France for the implementation of an alternative to public financing of health care. In the absence of progress, some regional health agencies are engaged in work related to the reallocation of public finances between psychiatric institutions. We propose a reflection with suggestion on the method proposed by the Provence Alpes Côte d'Azur Regional Health Agency. Without questioning the need for a reallocation of resources between psychiatric institutions, the method proposed here needs to evolve further to be applied in a legitimate and appropriate manner. There is a kind of urgency for a reallocation of resources between psychiatric institutions in France, but it implies a collective thinking and especially the definition of evaluation procedures for the selected models. These conditions are necessary to guarantee the quality of French psychiatry and equity in access to psychiatric care.

  7. Chikungunya outbreak in Montpellier, France, September to October 2014.

    PubMed

    Delisle, E; Rousseau, C; Broche, B; Leparc-Goffart, I; L'Ambert, G; Cochet, A; Prat, C; Foulongne, V; Ferre, J B; Catelinois, O; Flusin, O; Tchernonog, E; Moussion, I E; Wiegandt, A; Septfons, A; Mendy, A; Moyano, M B; Laporte, L; Maurel, J; Jourdain, F; Reynes, J; Paty, M C; Golliot, F

    2015-04-30

    In October 2014, an outbreak of 12 autochthonous chikungunya cases, 11 confirmed and 1 probable, was detected in a district of Montpellier, a town in the south of France colonised by the vector Aedes albopictus since 2010. A case returning from Cameroon living in the affected district was identified as the primary case. The epidemiological investigations and the repeated vector control treatments performed in the area and around places frequented by cases helped to contain the outbreak. In 2014, the chikungunya and dengue surveillance system in mainland France was challenged by numerous imported cases due to the chikungunya epidemic ongoing in the Caribbean Islands. This first significant outbreak of chikungunya in Europe since the 2007 Italian epidemic, however, was due to an East Central South African (ECSA) strain, imported by a traveller returning from West Africa. Important lessons were learned from this episode, which reminds us that the threat of a chikungunya epidemic in southern Europe is real.

  8. The future of astronomy PhDs in France

    NASA Astrophysics Data System (ADS)

    Boissier, S.

    2012-12-01

    This contribution presents a poll undertaken at the beginning of 2012, and addressed to every doctor in astronomy who obtained his/her degree in France. Its goal is to motivate the French astronomical community to think and discuss about what should be the training of PhDs, and what should be its objective. Further discussions and reactions can be posted e.g. on {http://docastro.blogspot.fr/}. A worrying results from the poll is that the majority of the participants would not encourage a young student to start a thesis in astronomy. The main reasons for this fact may be the high pressure on astronomy positions and the little interest a doctorate has for other careers in France. I suggest we either have to modify our training or reduce the number of thesis starting each year in astronomy.

  9. France tries to save its ailing national health insurance system.

    PubMed

    Sorum, Paul Clay

    2005-07-01

    France has provided universal health care through employment-based health insurance funds. As its governments have increasingly used tax revenues to supplement payroll levies, they have assumed a larger role. Faced with widening deficits in the funds' accounts, the National Assembly adopted in August 2004 legislation designed to decrease health expenses, increase revenues to the funds, and improve quality of care. The apparent impacts of the so-called Douste-Blazy law are to reaffirm social solidarity and equality of access; to reinforce central control rather than relying more on decentralized and market forces; to give the now-unified funds a stronger director, shielded not only from labor and business but also, possibly, from the central government; to allow French private physicians to retain their unrivaled freedom of prescription; and to continue France's reliance on taxes as well as payroll levies to finance its health care. PMID:16022215

  10. [Study on two manuscripts with colored illustrations collected in France].

    PubMed

    Liu, Yu-Ping; Cao, Hui

    2013-09-01

    Two manuscripts with colored illustrations in French libraries were investigated. The research showed that: the first manuscript with colored pictures include 2 volumes, titled Animaux et Plantes de Chine collected in Library of Museum National d'Historie Naturelle (MNHN);the other manuscript with colored pictures has only 1 volume, titled Botanique Chinoise collected in Library of Societe Asiatique, College de France, which were identified as illustrations of Ben cao gang mu (Compendium of Materia Medica) (1640 edition) by Li Shi-zhen. These pictures were copied by P. d'Incarville, and are similar to Plantes fleurs et arbres de Chine in Bibliotheque de l'Institut de Franceand, Collection de Plantes Veneneuses de la Chine Gravees et Imprimees en Couleurs par les Missionnaries Jesuites in Bibliotheque Nationale de France, respectively. The latter two manuscripts were identified as illustrations of Ben cao pin hui jing yao (Essential Collections of Materia Medica) (1700 edition).

  11. The GMO case in France: politics, lawlessness and postmodernism.

    PubMed

    Kuntz, Marcel

    2014-07-01

    The GMO debacle in France is analyzed in the light of the balance of forces around this controversy, the changes in position of governments and the opponents' strategic use of intimidation. These factors have caused insurmountable difficulties for scientific experimentations and assessment of the technology, as well as for farmers attempting to grow GM maize in this country. The change from a "modern" to a "postmodern" framing of official public debates and scientific institutions has not appeased confrontations concerning GMOs. PMID:25437234

  12. [The employment of foreigners and policy toward foreigners in France].

    PubMed

    Werner, H

    1983-01-01

    The historical background of international labor migration to France is briefly reviewed, and data are presented on the development and structure of the foreign labor force and the foreign population between 1946 and the present. Consideration is then given to the development of migration policies after World War II. Attempts to curb the number of illegal migrants through legislation and the promotion of return migration are described, and the recent policy allowing reunion of family members but penalizing illegal employment is discussed.

  13. Vichy France and the continuity of medical nationalism.

    PubMed

    Evleth, D

    1995-04-01

    This paper reviews the rise of medical nationalism and protectionism in France from the end of the nineteenth century through to the 1940s, with an emphasis on the Vichy period. It presents this nationalism as part of a continuity, showing its beginnings well before the coming of the Vichy government, its extremes under this government, and its continuation after the fall of the Vichy government, although retreating from its more extreme positions.

  14. The GMO case in France: politics, lawlessness and postmodernism.

    PubMed

    Kuntz, Marcel

    2014-07-01

    The GMO debacle in France is analyzed in the light of the balance of forces around this controversy, the changes in position of governments and the opponents' strategic use of intimidation. These factors have caused insurmountable difficulties for scientific experimentations and assessment of the technology, as well as for farmers attempting to grow GM maize in this country. The change from a "modern" to a "postmodern" framing of official public debates and scientific institutions has not appeased confrontations concerning GMOs.

  15. Sea surface temperature of the coastal zones of France

    NASA Technical Reports Server (NTRS)

    Deschamps, P. Y.; Crepon, M.; Monget, J. M.; Verger, F. (Principal Investigator); Frouin, R.; Cassanet, J.; Wald, L.

    1980-01-01

    The various thermal gradients in the coastal zones of France were mapped with regard to natural phenomena and man made thermal effluents. The mesoscale thermal features of the English Channel, the Bay of Biscay, and the northwestern Mediterranean Sea were also studied. The evolution of the thermal gradients generated by the main estuaries of the French coastal zones was investigated along with the modeling of diurnal heating of the sea surface and its influence on the oceanic surface layers.

  16. SurR regulates hydrogen production in Pyrococcus furiosus by a sulfur-dependent redox switch

    PubMed Central

    Yang, Hua; Lipscomb, Gina L.; Keese, Annette M.; Schut, Gerrit J.; Thomm, Michael; Adams, Michael W. W.; Wang, Bi Cheng; Scott, Robert A.

    2010-01-01

    SUMMARY We present structural and biochemical evidence for a redox switch in the archaeal transcriptional regulator SurR of Pyrococcus furiosus, a hyperthermophilic anaerobe. P. furiosus produces H2 during fermentation, but undergoes a metabolic shift to produce H2S when elemental sulfur (S0) becomes available. Changes in gene expression occur within minutes of S0 addition, and the majority of these S0-responsive genes are regulatory targets of SurR, a key regulator involved in primary S0 response. SurR was shown in vitro to have dual functionality, activating transcription of some of these genes, notably the hydrogenase operons, and repressing others, including a gene encoding sulfur reductase. This work demonstrates via biochemical and structural evidence that the activity of SurR is modulated by cysteine residues in a CxxC motif that constitute a redox switch. Oxidation of the switch with S0 inhibits sequence-specific DNA binding by SurR, leading to deactivation of genes related to H2 production and derepression of genes involved in S0 metabolism. PMID:20598080

  17. Molecular Characterization of Cryptosporidium Isolates Obtained from Humans in France

    PubMed Central

    Guyot, K.; Follet-Dumoulin, A.; Lelièvre, E.; Sarfati, C.; Rabodonirina, M.; Nevez, G.; Cailliez, J. C.; Camus, D.; Dei-Cas, E.

    2001-01-01

    Cryptosporidium parvum is usually considered the agent of human cryptosporidiosis. However, only in the last few years, molecular biology-based methods have allowed the identification of Cryptosporidium species and genotypes, and only a few data are available from France. In the present work, we collected samples of whole feces from 57 patients from France (11 immunocompetent patients, 35 human immunodeficiency virus [HIV]-infected patients, 11 immunocompromised but non-HIV-infected patients) in whom Cryptosporidium oocysts were recognized by clinical laboratories. A fragment of the Cryptosporidium 18S rRNA gene encompassing the hypervariable region was amplified by PCR and sequenced. The results revealed that the majority of the patients were infected with cattle (29 of 57) or human (18 of 57) genotypes of Cryptosporidium parvum. However, a number of immunocompromised patients were infected with C. meleagridis (3 of 57), C. felis (6 of 57), or a new genotype of C. muris (1 of 57). This is the first report of the last three species of Cryptosporidium in humans in France. These results indicate that immunocompromised individuals are susceptible to a wide range of Cryptosporidium species and genotypes. PMID:11574558

  18. Prevalence of Anaplasma phagocytophilum in small rodents in France.

    PubMed

    Chastagner, A; Moinet, M; Perez, G; Roy, E; McCoy, K D; Plantard, O; Agoulon, A; Bastian, S; Butet, A; Rantier, Y; Verheyden, H; Cèbe, N; Leblond, A; Vourc'h, G

    2016-07-01

    Anaplasma phagocytophilum is an emerging zoonotic tick-borne pathogen affecting a wide range of mammals. Rodents are suspected to be natural reservoirs for this bacterium, but their role in the epidemiologic cycles affecting domestic animals and wild ungulates has not been demonstrated. This study aimed to improve our knowledge on A. phagocytophilum prevalence in Apodemus sylvaticus, A. flavicollis and Myodes glareolus using data collected in 2010 in one area in eastern France and in 2012-2013 in two others areas in western France. Rodents were captured in each site and infection was tested using qualitative real-time PCR assays on either blood or spleen samples. Prevalence showed high variability among sites. The highest prevalence was observed in the most eastern site (with an average infection rate of 22.8% across all species), whereas no rodent was found to be PCR positive in the south-west site and only 6.6% were positive in the north-west of France. Finally, a significant increase in prevalence was observed in autumn samples compared to spring samples in the north-west, but no change was found in the other two sites.

  19. The Activity of Escherichia coli Chaperone SurA Is Regulated by Conformational Changes Involving a Parvulin Domain

    PubMed Central

    Soltes, Garner R.; Schwalm, Jaclyn; Ricci, Dante P.

    2016-01-01

    ABSTRACT The periplasmic chaperone SurA is critical for the biogenesis of outer membrane proteins (OMPs) and, thus, the maintenance of membrane integrity in Escherichia coli. The activity of this modular chaperone has been attributed to a core chaperone module, with only minor importance assigned to the two SurA peptidyl-prolyl isomerase (PPIase) domains. In this work, we used synthetic phenotypes and covalent tethering to demonstrate that the activity of SurA is regulated by its PPIase domains and, furthermore, that its activity is correlated with the conformational state of the chaperone. When combined with mutations in the β-barrel assembly machine (BAM), SurA mutations resulting in deletion of the second parvulin domain (P2) inhibit OMP assembly, suggesting that P2 is involved in the regulation of SurA. The first parvulin domain (P1) potentiates this autoinhibition, as mutations that covalently tether the P1 domain to the core chaperone module severely impair OMP assembly. Furthermore, these inhibitory mutations negate the suppression of and biochemically stabilize the protein specified by a well-characterized gain-of-function mutation in P1, demonstrating that SurA cycles between distinct conformational and functional states during the OMP assembly process. IMPORTANCE This work reveals the reversible autoinhibition of the SurA chaperone imposed by a heretofore underappreciated parvulin domain. Many β-barrel-associated outer membrane (OM) virulence factors, including the P-pilus and type I fimbriae, rely on SurA for proper assembly; thus, a mechanistic understanding of SurA function and inhibition may facilitate antibiotic intervention against Gram-negative pathogens, such as uropathogenic Escherichia coli, E. coli O157:H7, Shigella, and Salmonella. In addition, SurA is important for the assembly of critical OM biogenesis factors, such as the lipopolysaccharide (LPS) transport machine, suggesting that specific targeting of SurA may provide a useful means to

  20. Long-Term Care Financing: Lessons From France

    PubMed Central

    Doty, Pamela; Nadash, Pamela; Racco, Nathalie

    2015-01-01

    Context An aging population leads to a growing demand for long-term services and supports (LTSS). In 2002, France introduced universal, income-adjusted, public long-term care coverage for adults 60 and older, whereas the United States funds means-tested benefits only. Both countries have private long-term care insurance (LTCI) markets: American policies create alternatives to out-of-pocket spending and protect purchasers from relying on Medicaid. Sales, however, have stagnated, and the market's viability is uncertain. In France, private LTCI supplements public coverage, and sales are growing, although its potential to alleviate the long-term care financing problem is unclear. We explore whether France's very different approach to structuring public and private financing for long-term care could inform the United States’ long-term care financing reform efforts. Methods We consulted insurance experts and conducted a detailed review of public reports, academic studies, and other documents to understand the public and private LTCI systems in France, their advantages and disadvantages, and the factors affecting their development. Findings France provides universal public coverage for paid assistance with functional dependency for people 60 and older. Benefits are steeply income adjusted and amounts are low. Nevertheless, expenditures have exceeded projections, burdening local governments. Private supplemental insurance covers 11% of French, mostly middle-income adults (versus 3% of Americans 18 and older). Whether policyholders will maintain employer-sponsored coverage after retirement is not known. The government's interest in pursuing an explicit public/private partnership has waned under President François Hollande, a centrist socialist, in contrast to the previous center-right leader, President Nicolas Sarkozy, thereby reducing the prospects of a coordinated public/private strategy. Conclusions American private insurers are showing increasing interest in long

  1. Structure and function of an archaeal homolog of survival protein E (SurEalpha): an acid phosphatase with purine nucleotide specificity.

    PubMed

    Mura, Cameron; Katz, Jonathan E; Clarke, Steven G; Eisenberg, David

    2003-03-01

    The survival protein E (SurE) family was discovered by its correlation to stationary phase survival of Escherichia coli and various repair proteins involved in sustaining this and other stress-response phenotypes. In order to better understand this ancient and well-conserved protein family, we have determined the 2.0A resolution crystal structure of SurEalpha from the hyperthermophilic crenarchaeon Pyrobaculum aerophilum (Pae). This first structure of an archaeal SurE reveals significant similarities to and differences from the only other known SurE structure, that from the eubacterium Thermatoga maritima (Tma). Both SurE monomers adopt similar folds; however, unlike the Tma SurE dimer, crystalline Pae SurEalpha is predominantly non-domain swapped. Comparative structural analyses of Tma and Pae SurE suggest conformationally variant regions, such as a hinge loop that may be involved in domain swapping. The putative SurE active site is highly conserved, and implies a model for SurE bound to a potential substrate, guanosine-5'-monophosphate (GMP). Pae SurEalpha has optimal acid phosphatase activity at temperatures above 90 degrees C, and is less specific than Tma SurE in terms of metal ion requirements. Substrate specificity also differs between Pae and Tma SurE, with a more specific recognition of purine nucleotides by the archaeal enzyme. Analyses of the sequences, phylogenetic distribution, and genomic organization of the SurE family reveal examples of genomes encoding multiple surE genes, and suggest that SurE homologs constitute a broad family of enzymes with phosphatase-like activities.

  2. Seasonal modulation of the seismicity in Provence (France): from early historical analysis to case studies and mechanisms

    NASA Astrophysics Data System (ADS)

    Le Dortz, K.; Bollinger, L.; Leroy, Y. M.

    2011-12-01

    Southeastern France is a region of moderate seismic activity characterised by shallow seismic events, regularly felt and reported by local inhabitants in several districts. An analysis of one of the very first earthquakes catalogues covering the region lead Alexis Perrey, a famous author of regional monographs and annual catalogues of seismicity, to propose in 1845 that the area was characterised by an annual periodicity of earthquakes. The seismic activity appears to be more predominant during the autumn and winter months than during summer months. Although not exempt of biases, his analysis is interesting, his so-called seismic curves being aftershock-depleted by a 'unit-earthquake-technique' he developed for the occasion. Indeed, several atypical earthquake swarms, lasting days or months, regularly associated by the observers with seasonal floods or catastrophic storms, happen in the region. Several localities have also been damaged by some of these seismic events that can be destructive. We first review Perrey's seismicity analysis. We then focus on the description of some of the Provence regions that seem prone to atypical shallow seismicity and have a significant weight on the regional catalogue. We finally discuss several mechanisms able to modulate the local and/or regional seismicity. Most of these mechanisms involve the local hydrology and influence in a subtle way the local stresses at shallow depths. Perrey, A. (1845) Mémoire sur les tremblements de terre ressentis dans le bassin du Rhône, Annales des sciences physiques et naturelles, d'agriculture et d'industrie, 265-346.

  3. HIV type 1 diversity in northern Paris, France.

    PubMed

    Simon, F; Loussert-Ajaka, I; Damond, F; Saragosti, S; Barin, F; Brun-Vézinet, F

    1996-10-10

    During a 6-month period, we studied the diversity of HIV-1 subtypes in 392 adult patients seen in Bichat-Claude Bernard Hospital, northern Paris, France. All the samples were serotyped and a subset was genotyped by means of HMA. Serotyping was performed with a new peptide subtype-specific EIA (SSEIA), based on in vitro competition for antibody binding between the representative V3 peptides of the different clades (A to E). HMA with plasmids from clades A to H gave unambiguous results on 105 of the 116 samples tested. The agreement between SSEIA and HMA was 36/41 for subtype B, 2/2 for subtype D, and 4/5 for subtype E. We found a discrepancy in the results between clade A and C: the patients with sera reacting to peptide C were confirmed by HMA as being infected by clade A strains. Three patients reactive with peptide A were infected by a subtype F. These results indicate that peptide cross-reactivity, even in the SSEIA format, hinders serotyping. In 11 samples, all from African patients, the subtype remained indeterminate because PCR or HMA failed. Caucasian patients (n = 223) were mainly infected by subtype B. HMA and/or SSEIA revealed non-subtype B infection in 14 Caucasians, who were infected by the sexual route overseas or in France. Patients originating from other countries (mainly in Africa) exhibited a broad strain diversity, with most of the different subtypes so far described being represented. This study confirms the frequency of subtype B strains in Caucasians living in France, but emphasizes the emergence of the different HIV-1 subtypes in Paris, together with the extent of strain trafficking. Discordances between serotype and genotype assays confirm that both tests require additional development.

  4. Improving ammonia emissions in air quality modelling for France

    NASA Astrophysics Data System (ADS)

    Hamaoui-Laguel, Lynda; Meleux, Frédérik; Beekmann, Matthias; Bessagnet, Bertrand; Génermont, Sophie; Cellier, Pierre; Létinois, Laurent

    2014-08-01

    We have implemented a new module to improve the representation of ammonia emissions from agricultural activities in France with the objective to evaluate the impact of such emissions on the formation of particulate matter modelled with the air quality model CHIMERE. A novel method has been set up for the part of ammonia emissions originating from mineral fertilizer spreading. They are calculated using the one dimensional 1D mechanistic model “VOLT'AIR” which has been coupled with data on agricultural practices, meteorology and soil properties obtained at high spatial resolution (cantonal level). These emissions display high spatiotemporal variations depending on soil pH, rates and dates of fertilization and meteorological variables, especially soil temperature. The emissions from other agricultural sources (animal housing, manure storage and organic manure spreading) are calculated using the national spatialised inventory (INS) recently developed in France. The comparison of the total ammonia emissions estimated with the new approach VOLT'AIR_INS with the standard emissions provided by EMEP (European Monitoring and Evaluation Programme) used currently in the CHIMERE model shows significant differences in the spatiotemporal distributions. The implementation of new ammonia emissions in the CHIMERE model has a limited impact on ammonium nitrate aerosol concentrations which only increase at most by 10% on the average for the considered spring period but this impact can be more significant for specific pollution episodes. The comparison of modelled PM10 (particulate matter with aerodynamic diameter smaller than 10 μm) and ammonium nitrate aerosol with observations shows that the use of the new ammonia emission method slightly improves the spatiotemporal correlation in certain regions and reduces the negative bias on average by 1 μg m-3. The formation of ammonium nitrate aerosol depends not only on ammonia concentrations but also on nitric acid availability, which

  5. Spatial distribution of soil organic carbon stocks in France

    NASA Astrophysics Data System (ADS)

    Martin, M. P.; Wattenbach, M.; Smith, P.; Meersmans, J.; Jolivet, C.; Boulonne, L.; Arrouays, D.

    2011-05-01

    Soil organic carbon plays a major role in the global carbon budget, and can act as a source or a sink of atmospheric carbon, thereby possibly influencing the course of climate change. Changes in soil organic carbon (SOC) stocks are now taken into account in international negotiations regarding climate change. Consequently, developing sampling schemes and models for estimating the spatial distribution of SOC stocks is a priority. The French soil monitoring network has been established on a 16 km × 16 km grid and the first sampling campaign has recently been completed, providing around 2200 measurements of stocks of soil organic carbon, obtained through an in situ composite sampling, uniformly distributed over the French territory. We calibrated a boosted regression tree model on the observed stocks, modelling SOC stocks as a function of other variables such as climatic parameters, vegetation net primary productivity, soil properties and land use. The calibrated model was evaluated through cross-validation and eventually used for estimating SOC stocks for mainland France. Two other models were calibrated on forest and agricultural soils separately, in order to assess more precisely the influence of pedo-climatic variables on SOC for such soils. The boosted regression tree model showed good predictive ability, and enabled quantification of relationships between SOC stocks and pedo-climatic variables (plus their interactions) over the French territory. These relationships strongly depended on the land use, and more specifically, differed between forest soils and cultivated soil. The total estimate of SOC stocks in France was 3.260 ± 0.872 PgC for the first 30 cm. It was compared to another estimate, based on the previously published European soil organic carbon and bulk density maps, of 5.303 PgC. We demonstrate that the present estimate might better represent the actual SOC stock distributions of France, and consequently that the previously published approach at the

  6. Spatial distribution of soil organic carbon stocks in France

    NASA Astrophysics Data System (ADS)

    Martin, M. P.; Wattenbach, M.; Smith, P.; Meersmans, J.; Jolivet, C.; Boulonne, L.; Arrouays, D.

    2010-11-01

    Soil organic carbon plays a major role in the global carbon budget, and can act as a source or a sink of atmospheric carbon, whereby it can influence the course of climate change. Changes in soil organic soil stocks (SOCS) are now taken into account in international negotiations regarding climate change. Consequently, developing sampling schemes and models for estimating the spatial distribution of SOCS is a priority. The French soil monitoring network has been established on a 16 km × 16 km grid and the first sampling campaign has recently been completed, providing circa 2200 measurements of stocks of soil organic carbon, obtained through an in situ composite sampling, uniformly distributed over the French territory. We calibrated a boosted regression tree model on the observed stocks, modelling SOCS as a function of other variables such as climatic parameters, vegetation net primary productivity, soil properties and land use. The calibrated model was evaluated through cross-validation and eventually used for estimating SOCS for the whole of metropolitan France. Two other models were calibrated on forest and agricultural soils separately, in order to assess more precisely the influence of pedo-climatic variables on soil organic carbon for such soils. The boosted regression tree model showed good predictive ability, and enabled quantification of relationships between SOCS and pedo-climatic variables (plus their interactions) over the French territory. These relationship strongly depended on the land use, and more specifically differed between forest soils and cultivated soil. The total estimate of SOCS in France was 3.260 ± 0.872 PgC for the first 30 cm. It was compared to another estimate, based on the previously published European soil organic carbon and bulk density maps, of 5.303 PgC. We demonstrate that the present estimate might better represent the actual SOCS distributions of France, and consequently that the previously published approach at the European

  7. Large number of imported chikungunya cases in mainland France, 2014: a challenge for surveillance and response.

    PubMed

    Paty, M C; Six, C; Charlet, F; Heuzé, G; Cochet, A; Wiegandt, A; Chappert, J L; Dejour-Salamanca, D; Guinard, A; Soler, P; Servas, V; Vivier-Darrigol, M; Ledrans, M; Debruyne, M; Schaal, O; Jeannin, C; Helynck, B; Leparc-Goffart, I; Coignard, B

    2014-01-01

    During the summer of 2014, all the pre-requisites for autochthonous transmission of chikungunya virus are present in southern France: a competent vector, Aedes albopictus, and a large number of travellers returning from the French Caribbean islands where an outbreak is occurring. We describe the system implemented for the surveillance of chikungunya and dengue in mainland France. From 2 May to 4 July 2014, there were 126 laboratory-confirmed imported chikungunya cases in mainland France.

  8. What strategy should France implement for H2020?

    PubMed

    Dhainaut, Jean-François; Diebolt, Vincent; Pouletty-Lefèbvre, Brigitte; Baker, Angela; Bassompierre, François; Borel, Thomas; Braunstein, David; Demotes, Jacques; François, Bruno; Huet, Stéphane; Micallef, Joëlle; Misse, Christophe; Molon, Annamaria; Rascol, Olivier; Ravoire, Sophie; Schwartz, Bertrand; Donne, Nathalie; Donne, Nathalie; Fusaï, Guillaume; Pouletty, Philippe; Vicaut, Eric

    2015-01-01

    The initiation of Horizon 2020--the European Union's 8th Framework Programme for Research and Innovation, allotted a budget of 79 billion euros--provides an opportunity to review France's participation in previous Framework Programmes. Indeed, French participation does not match either its scientific importance or its financial investment. While France contributed 16.5 to 17% of the EU's 7th Framework Programme research budget, its return through the funding of coordinated projects in which French teams are participating stands at around 12.5 to 13%, a shortfall of 600 million euros. Although the situation depends on the type of activity, French participation in clinical research appears to be smaller than that of its neighbours, with fewer responses to European calls for proposals. While France has many assets, which include the assured funding of clinical research, structured thematic networks and the initiation of major national programmes, it suffers from the dilution of resources due to France's regional development policy, the lack of multidisciplinarity and the ignorance of both the medical and scientific community and the institutions to which they belong as to how Horizon 2020 actually works. We propose three types of strategy to encourage proposals for coordinated clinical research projects or projects involving French teams, and to help in the drawing up of applications: Broaden the vision of our children, students and colleagues, helping them to adapt to the globalisation of knowledge throughout their educational and professional lives. Recognise the value of European actions to influence the European landscape and change mentalities. Help and support project initiators by pooling skills within a limited number of expert centres designed to assist them in their funding application. • Broaden the vision of our children, students and colleagues, helping them to adapt to the globalisation of knowledge throughout their educational and professional lives

  9. [Ventilators for anesthesia. Models available in France. Criteria for choice].

    PubMed

    Otteni, J C; Ancellin, J; Cazalaà, J B; Clergue, F; Feiss, P; Fougère, S; Nivoche, Y; Safran, D

    1995-01-01

    This update article discusses the criteria for the choice of an anaesthetic machine and provides a short analysis of the main components of the models commercialized in France in 1994. The following items are considered: the design of the machine, the fresh gas delivery system, the anaesthesia breathing system(s), the ventilator and the waste gas scavenging system, the monitors associated with the machine and other criteria such as facility of learning to run the machine and of its daily use, ease of "in-house" maintenance and quality of after-sales service, cost of the machine and of its use (driving gas, disposable equipment). PMID:7677278

  10. The GMO case in France: Politics, lawlessness and postmodernism

    PubMed Central

    Kuntz, Marcel

    2014-01-01

    The GMO debacle in France is analyzed in the light of the balance of forces around this controversy, the changes in position of governments and the opponents’ strategic use of intimidation. These factors have caused insurmountable difficulties for scientific experimentations and assessment of the technology, as well as for farmers attempting to grow GM maize in this country. The change from a “modern” to a “postmodern” framing of official public debates and scientific institutions has not appeased confrontations concerning GMOs. PMID:25437234

  11. 10-year update of Stirling cryogenic coolers in France

    NASA Astrophysics Data System (ADS)

    Martin, Jean-Yves

    2000-12-01

    This paper enters in the scope of the session on 10-year update of IR in France. Cryotechnologies is a leader in both the French and European markets as a designer and manufacturer of cryogenic coolers. Serial production of the first generation of Stirling cryocoolers started at Cryotechnologies in the late eighties. A range of integral Stirling coolers is nowadays available and completes the existing range of split Stirling cryocoolers. Technical improvements are keeping up with the market evolutions and new potential applications (costs reduction, fast cooldown time, increase of cooling power, very high reliability, pulse tube cold finger).

  12. Severe peritonitis due to Balantidium coli acquired in France.

    PubMed

    Ferry, T; Bouhour, D; De Monbrison, F; Laurent, F; Dumouchel-Champagne, H; Picot, S; Piens, M A; Granier, P

    2004-05-01

    The case reported here concerns an alcoholic pork-butcher who presented with severe colitis with peritonitis, caused by the only ciliate protozoan capable of infecting humans, Balantidium coli. This parasite is common in a variety of domestic and wild mammals, mainly pigs; however, its prevalence rate in humans is very low--particularly in industrialised, northern countries, including France. The infection is most frequently acquired by ingesting food or water contaminated by pig faeces, and it may be asymptomatic or may cause acute diarrhoea. Specific antibiotic treatment is efficacious, and it is important to consider the risk of this parasitic disease in susceptible patients presenting with bloody diarrhoea. PMID:15112068

  13. Remote sensing of biomass of salt marsh vegetation in France

    NASA Technical Reports Server (NTRS)

    Gross, M. F.; Klemas, V.; Levasseur, J. E.

    1988-01-01

    Spectral data (gathered using a hand-held radiometer) and harvest data were collected from four salt marsh vegetation types in Brittany, France, to develop equations predicting live aerial biomass from spectral measurements. Remote sensing estimates of biomass of the general salt marsh community (GSM) and of Spartina alterniflora can be obtained throughout the growing season if separate biomass prediction equations are formulated for different species mixtures (for the GSM) and for different canopy types (for S. alterniflora). Results suggest that remote sensing will not be useful for predicting Halimione portulacoides biomass, but can be used to estimate Puccinellia maritima biomass early in the growing season.

  14. What strategy should France implement for H2020?

    PubMed

    Dhainaut, Jean-François; Diebolt, Vincent; Pouletty-Lefèbvre, Brigitte; Baker, Angela; Bassompierre, François; Borel, Thomas; Braunstein, David; Demotes, Jacques; François, Bruno; Huet, Stéphane; Micallef, Joëlle; Misse, Christophe; Molon, Annamaria; Rascol, Olivier; Ravoire, Sophie; Schwartz, Bertrand; Donne, Nathalie; Donne, Nathalie; Fusaï, Guillaume; Pouletty, Philippe; Vicaut, Eric

    2015-01-01

    The initiation of Horizon 2020--the European Union's 8th Framework Programme for Research and Innovation, allotted a budget of 79 billion euros--provides an opportunity to review France's participation in previous Framework Programmes. Indeed, French participation does not match either its scientific importance or its financial investment. While France contributed 16.5 to 17% of the EU's 7th Framework Programme research budget, its return through the funding of coordinated projects in which French teams are participating stands at around 12.5 to 13%, a shortfall of 600 million euros. Although the situation depends on the type of activity, French participation in clinical research appears to be smaller than that of its neighbours, with fewer responses to European calls for proposals. While France has many assets, which include the assured funding of clinical research, structured thematic networks and the initiation of major national programmes, it suffers from the dilution of resources due to France's regional development policy, the lack of multidisciplinarity and the ignorance of both the medical and scientific community and the institutions to which they belong as to how Horizon 2020 actually works. We propose three types of strategy to encourage proposals for coordinated clinical research projects or projects involving French teams, and to help in the drawing up of applications: Broaden the vision of our children, students and colleagues, helping them to adapt to the globalisation of knowledge throughout their educational and professional lives. Recognise the value of European actions to influence the European landscape and change mentalities. Help and support project initiators by pooling skills within a limited number of expert centres designed to assist them in their funding application. • Broaden the vision of our children, students and colleagues, helping them to adapt to the globalisation of knowledge throughout their educational and professional lives

  15. The contract facilities for gamma irradiation at Dagneux, France

    NASA Astrophysics Data System (ADS)

    Pellerin, D.; Kavanagh, M. T.

    CONSERVATOME SA have operated a facility at DAGNEUX near LYON, France since 1961. This operation is among the very first of its kind in the entire world. The process is based on gamma rays from Cobalt 60 of which there are three separate units. In addition there is a small experimental unit using Cesium 137. At present CONSERVATOME is owned by TRANSNUCLEAIRE and EPICEA as principal shareholders and so has the support of the French Atomic Energy Commission. This paper describes the larger D3 unit and reviews some of the products treated at DAGNEUX.

  16. Remote Operations of the Canada-France-Hawaii Telescope

    NASA Astrophysics Data System (ADS)

    Vermeulen, T.; Thomas, J.; Burdullis, T.

    2014-05-01

    In 2007, the Canada-France-Hawaii Telescope (CFHT) started a project with the goal to enable remote control of the Mauna Kea observatory from the Headquarters facility in Waimea. After a few years of development effort the observatory has operated exclusively in a remote fashion since the beginning of 2011. This paper will discuss the entire lifecycle of the project from design and development to the successful implementation and ongoing operation of remote observing. Special emphasis will be given to the challenges, successes and lessons learned along the way.

  17. Time transfer by laser link between China and France

    NASA Astrophysics Data System (ADS)

    Zhao, C.; Ni, W. T.; Samain, E.

    2008-07-01

    To advance from milli-arcsecond to micro-arcsecond astrometry, time keeping capability and its comparison among different stations need to be improved and enhanced. The T2L2 (Time transfer by laser link) experiment under development at OCA and CNES to be launched in 2008 on Jason-2, allows the synchronization of remote clocks on Earth. It is based on the propagation of light pulses in space which is better controlled than propagation of radio waves. In this paper, characteristics are presented for both a common view and non-common view T2L2 comparisons of clocks between China and France.

  18. The Classroom as Big Sur: Notes on the Liaison Between Evaluation and Professional Growth

    ERIC Educational Resources Information Center

    Sneeden, Ralph

    2013-01-01

    Bill Frisell's new album ("Big Sur") was heralded with a short documentary about its impulse and inception: Frisell's retreat to an isolated coastal ranch in Central California. In the video, he describes the influence of the place, the dramatic and evocative landscape, and how it ultimately became the subject and theme for the…

  19. Seafloor Rocks and Sediments of the Continental Shelf From Monterey Bay to Point Sur, California

    USGS Publications Warehouse

    Eittreim, Stephen L.; Anima, Roberto J.; Stevenson, Andrew J.; Wong, Florence L.

    2000-01-01

    Introduction Acoustic swath mapping of the greater Monterey Bay area continental shelf from Point Ano Nuevo to Point Sur reveals complex patterns of rock outcrops on the shelf, and coarse sand bodies that occur in distinct depressions on the inner and mid-shelves. This publication portrays the seafloor components in a 36- by 48-inch map sheet at 1:100,000 scale.

  20. Reflections on "Petit Battement sur le Cou de Pied": Is It Still Relevant?

    ERIC Educational Resources Information Center

    Paskevska, Anna

    2007-01-01

    This article presents multiple perspectives of "petit battement sur le cou de pied". These perspectives include historical, biomechanical, and pedagogic points of view. The article offers useful information for ballet specialists and applied research studies aimed at ballet pedagogy. (Contains 2 tables and 5 figures.)

  1. Forensic mental health assessment in France: recommendations for quality improvement.

    PubMed

    Combalbert, Nicolas; Andronikof, Anne; Armand, Marine; Robin, Cécile; Bazex, Hélène

    2014-01-01

    The quality of forensic mental health assessment has been a growing concern in various countries on both sides of the Atlantic, but the legal systems are not always comparable and some aspects of forensic assessment are specific to a given country. This paper describes the legal context of forensic psychological assessment in France (i.e. pre-trial investigation phase entrusted to a judge, with mental health assessment performed by preselected professionals called "experts" in French), its advantages and its pitfalls. Forensic psychiatric or psychological assessment is often an essential and decisive element in criminal cases, but since a judiciary scandal which was made public in 2005 (the Outreau case) there has been increasing criticism from the public and the legal profession regarding the reliability of clinical conclusions. Several academic studies and a parliamentary report have highlighted various faulty aspects in both the judiciary process and the mental health assessments. The heterogeneity of expert practices in France appears to be mainly related to a lack of consensus on several core notions such as mental health diagnosis or assessment methods, poor working conditions, lack of specialized training, and insufficient familiarity with the Code of Ethics. In this article we describe and analyze the French practice of forensic psychologists and psychiatrists in criminal cases and propose steps that could be taken to improve its quality, such as setting up specialized training courses, enforcing the Code of Ethics for psychologists, and calling for consensus on diagnostic and assessment methods. PMID:24631526

  2. Comparing soil moisture retrievals from SMOS and ASCAT over France

    NASA Astrophysics Data System (ADS)

    Parrens, M.; Zakharova, E.; Lafont, S.; Calvet, J.-C.; Kerr, Y.; Wagner, W.; Wigneron, J.-P.

    2011-09-01

    The first products derived over France in 2010 from the L-band brightness temperatures (Tb) measured by the SMOS (Soil Moisture and Ocean Salinity) satellite, launched in November 2009, were compared with the surface soil moisture (SSM) estimates produced by the C-band Advanced Scatterometter, ASCAT, launched in 2006 on board METOP-A. SMOS and ASCAT SSM products were compared with the simulations of the ISBA-A-gs model and with in situ measurements from the SMOSMANIA network, including 21 stations located in southern France. ASCAT tended to correlate better than SMOS with ISBA-A-gs. The significant anomaly correlation coefficients between in situ observations and the SMOS (ASCAT) product ranged from 0.23 to 0.48 (0.35 to 0.96). However, in wet conditions, similar results between the two satellite products were found. An attempt was made to derive SSM from regressed empirical logarithmic equations using a combination of SMOS Tb at different incidence angles and different polarizations, and the Leaf Area Index (LAI) modeled by ISBA-A-gs. The analysis of the intercept coefficient of the regression showed an impact of topography. A similar analysis applied to ASCAT and SMOS SSM values showed a more limited impact of topography on the intercept coefficient of the SMOS SSM product, while fewer residual geographic patterns were found for the ASCAT SSM.

  3. Comparing soil moisture retrievals from SMOS and ASCAT over France

    NASA Astrophysics Data System (ADS)

    Parrens, M.; Zakharova, E.; Lafont, S.; Calvet, J.-C.; Kerr, Y.; Wagner, W.; Wigneron, J.-P.

    2012-02-01

    The first products derived over France in 2010 from the L-band brightness temperatures (Tb) measured by the SMOS (Soil Moisture and Ocean Salinity) satellite, launched in November 2009, were compared with the surface soil moisture (SSM) estimates produced by the C-band Advanced Scatterometer, ASCAT, launched in 2006 on board METOP-A. SMOS and ASCAT SSM products were compared with the simulations of the ISBA-A-gs model and with in situ measurements from the SMOSMANIA network, including 21 stations located in southern France. ASCAT tended to correlate better than SMOS with ISBA-A-gs. The significant anomaly correlation coefficients between in situ observations and the SMOS (ASCAT) product ranged from 0.23 to 0.48 (0.35 to 0.96). However, in wet conditions, similar results between the two satellite products were found. An attempt was made to derive SSM from regressed empirical logarithmic equations using a combination of SMOS Tb at different incidence angles and different polarizations, and the Leaf Area Index (LAI) modeled by ISBA-A-gs. The analysis of the intercept coefficient of the regression showed an impact of topography. A similar analysis applied to ASCAT and SMOS SSM values showed a more limited impact of topography on the intercept coefficient of the SMOS SSM product, while fewer residual geographic patterns were found for the ASCAT SSM.

  4. Wine and tobacco: risk factors for gastric cancer in France.

    PubMed

    Hoey, J; Montvernay, C; Lambert, R

    1981-06-01

    Cross-sectional studies in France have shown strong regional correlations between death rates from alcohol related diseases and death rates from gastric cancer. The present study involved 40 cases of newly diagnosed adenocarcinoma of the stomach and 168 control subjects with one of four other gastrointestinal diagnoses selected from the same hospital service during the same time period, 1978-1980. On the basis of a standard nutritional interview alcohol and particularly red wine were seen to be significant risk factors for this cancer (relative risks of 6.9 with 95% confidence limits (CL) of 3.3-14.3 for alcohol and 6.3 with CL 3.1-12.7 for wine). Smoking of one or more cigarettes per day was associated with a relative risk for gastric cancer of 4.8 with CL of 1.6-14.8. The presence of both risk factors was associated with a relative risk of 9.3 with 95% CL of 4.6-19.0. Possible confounding by age, smoking, and eating lettuce (a reported protective factor for gastric cancer in other studies) did not explain these results. The relative risks were consistently found and remained significant when each diagnostic group of control subjects was analyzed separately. These results suggest that alcohol, and particularly red wine, may be important risk factors for adenocarcinoma of the stomach in France. In addition, cigarette smoking, a risk factor in itself, when coupled with alcohol appears markedly to increase the risk.

  5. Obtaining reimbursement in France and Italy for new diabetes products.

    PubMed

    Schaefer, Elmar; Schnell, Gerald; Sonsalla, Jessica

    2015-01-01

    Manufacturers launching next-generation or innovative medical devices in Europe face a very heterogeneous reimbursement landscape, with each country having its own pathways, timing, requirements and success factors. We selected 2 markets for a deeper look into the reimbursement landscape: France, representing a country with central decision making with defined processes, and Italy, which delegates reimbursement decisions to the regional level, resulting in a less transparent approach to reimbursement. Based on our experience in working on various new product launches and analyzing recent reimbursement decisions, we found that payers in both countries do not reward improved next-generation products with incremental reimbursement. Looking at innovations, we observe that manufacturers face a challenging and lengthy process to obtain reimbursement. In addition, requirements and key success factors differ by country: In France, comparative clinical evidence and budget impact very much drive reimbursement decisions in terms of pricing and restrictions, whereas in Italy, regional key opinion leader (KOL) support and additional local observational data are key. PMID:25550411

  6. USA-France: Confronting two perspectives on shale gas

    NASA Astrophysics Data System (ADS)

    Gautier, C.; Fellous, J.

    2013-12-01

    Exploiting shale gas and oil can be seen from very different perspectives, whether you live in the US where it is a decade long reality shaping the country's energy landscape or in France, where it is banned by law since 2011. Beyond this situation, the overall legal framework that regulates (or not) environmental and water protection, the use of chemicals, land ownership and the exploitation of underground mineral resources, the attribution of licenses for exploration and exploitation, etc. in Europe (and particularly in France, the only European country with Bulgaria where hydraulic fracturation is strictly forbidden) and in the US is at complete variance. This presentation will discuss subsequent attitudes vis-à-vis exploration, exploitation, scientific research on shale gas and fracking, and public activism that has arisen as a result of environmental, socioeconomic and human concerns. It will compare and contrast the different views and look at lessons that can be learned from those differences. This work is building upon the experience of the authors who have studied the issues relating to energy, water, population and climate and their connections, as seen from both sides of the Atlantic.

  7. [Vauquelin: route from a thatched cottage to Institute of France].

    PubMed

    Lafont, O

    2014-07-01

    Nicolas Louis Vauquelin was born in a little thatched cottage in Saint-André-d'Hébertot, in Normandy, on May 16th 1763. He went to Rouen and then to Paris where he met Antoine de Fourcroy and became his co-worker and his friend. They published together sixty articles, and he published alone a hundred and twenty articles. He became a pharmacist in 1787. He occupied simultaneously or not many important University positions. He was Associate Professor at École polytechnique, Professor at École des mines, Professor at Collège de France, Director of School of Pharmacy, Professor at Museum d'histoire naturelle, Professor at Faculty of Medicine. He became Empire Knight, Member of Institute of France, Member and President of Academy of Medicine, Member and President of Society of Pharmacy. He discovered and isolated chrome and discovered beryllium. He was a very efficient professor and many of his students were well-known scientists. He died on November 14th 1829.

  8. Slavery, smallpox, and revolution: 1792 in Ile de France (Mauritius).

    PubMed

    Vaughan, M

    2000-12-01

    In 1792 a slave-ship arrived on the french Indian Ocean island of Ile de France (Mauritius) from South India, bringing with it smallpox. As the epidemic spread, a heated debate ensued over the practice of inoculation. The island was in the throes of revolutionary politics and the community of French colonists were acutely aware of their new rights as 'citizens'. In the course of the smallpox epidemic, many of the political tenisons of the period came to focus on the question of inoculation, and were played out on the bodies of slaves. Whilst some citizens asserted their right, as property owners, to inoculate their slaves, others, equally vehemently, objected to the practice and asserted their right to protect their slaves from infection. Eighteenth-century colonial medicine was largely geared to keeping the bodies of slaves and workers productive and useful, but formal medicine never had a monopoly. Slaves on Ile de France brought with them a rich array of medical beliefs and practices from Africa, India, and Madagascar. We have little direct historical evidence for these, but we do know that many slaves came from areas in which forces of smallpox inoculation were known and practised.

  9. Neanderthal infant and adult infracranial remains from Marillac (Charente, France).

    PubMed

    Dolores Garralda, María; Maureille, Bruno; Vandermeersch, Bernard

    2014-09-01

    At the site of Marillac, near the Ligonne River in Marillac-le-Franc (Charente, France), a remarkable stratigraphic sequence has yielded a wealth of archaeological information, palaeoenvironmental data, as well as faunal and human remains. Marillac must have been a sinkhole used by Neanderthal groups as a hunting camp during MIS 4 (TL date 57,600 ± 4,600BP), where Quina Mousterian lithics and fragmented bones of reindeer predominate. This article describes three infracranial skeleton fragments. Two of them are from adults and consist of the incomplete shafts of a right radius (Marillac 24) and a left fibula (Marillac 26). The third fragment is the diaphysis of the right femur of an immature individual (Marillac 25), the size and shape of which resembles those from Teshik-Tash and could be assigned to a child of a similar age. The three fossils have been compared with the remains of other Neanderthals or anatomically Modern Humans (AMH). Furthermore, the comparison of the infantile femora, Marillac 25 and Teshik-Tash, with the remains of several European children from the early Middle Ages clearly demonstrates the robustness and rounded shape of both Neanderthal diaphyses. Evidence of peri-mortem manipulations have been identified on all three bones, with spiral fractures, percussion pits and, in the case of the radius and femur, unquestionable cutmarks made with flint implements, probably during defleshing. Traces of periostosis appear on the fibula fragment and on the immature femoral diaphysis, although their aetiology remains unknown. PMID:24919796

  10. Forensic mental health assessment in France: recommendations for quality improvement.

    PubMed

    Combalbert, Nicolas; Andronikof, Anne; Armand, Marine; Robin, Cécile; Bazex, Hélène

    2014-01-01

    The quality of forensic mental health assessment has been a growing concern in various countries on both sides of the Atlantic, but the legal systems are not always comparable and some aspects of forensic assessment are specific to a given country. This paper describes the legal context of forensic psychological assessment in France (i.e. pre-trial investigation phase entrusted to a judge, with mental health assessment performed by preselected professionals called "experts" in French), its advantages and its pitfalls. Forensic psychiatric or psychological assessment is often an essential and decisive element in criminal cases, but since a judiciary scandal which was made public in 2005 (the Outreau case) there has been increasing criticism from the public and the legal profession regarding the reliability of clinical conclusions. Several academic studies and a parliamentary report have highlighted various faulty aspects in both the judiciary process and the mental health assessments. The heterogeneity of expert practices in France appears to be mainly related to a lack of consensus on several core notions such as mental health diagnosis or assessment methods, poor working conditions, lack of specialized training, and insufficient familiarity with the Code of Ethics. In this article we describe and analyze the French practice of forensic psychologists and psychiatrists in criminal cases and propose steps that could be taken to improve its quality, such as setting up specialized training courses, enforcing the Code of Ethics for psychologists, and calling for consensus on diagnostic and assessment methods.

  11. NATO SET-093 joint field experiment at Bourges, France

    NASA Astrophysics Data System (ADS)

    Marty, C.; Bruel, F.; Prieur, D.; Naz, P.; Miller, L. S.

    2009-05-01

    This paper describes the NATO Task Group SET-093/RTG53/MSE (referred to as TG-53 in this report) Acoustic Detection of Weapons Firing Joint Field Experiment II conducted at the Etablissement Technique de Bourges (ETBS), Bourges, France, during 16 to 27 June 2008. This field experiment is a follow-on to the NATO TG-53 Acoustic Detection of Weapons Firing Joint Field Experiment I conducted at the Yuma Proving Grounds (YPG), Yuma, Arizona, USA, during 31 October to 4 November 2005 [1]. The objectives of the joint experiment were: (i) to collect acoustic signatures of direct and indirect firings from weapons' such as small arms, mortars, artillery, rockets, and C4 explosives, (ii) to analyze the propagation effects of grassy, wooded, and urban terrains, (iii) to share signatures collected from a variety of acoustic sensors, on the ground and in the air, distributed over a wide area, and (iv) to demonstrate the interoperability of disparate sensors developed by the various nations involved. The participating NATO countries , including France, the Netherlands, the United Kingdom, Canada, and the United States of America, and Israel as well as part of the Mediterranean dialogue countries, deployed nearly 90 sensors and sensor systems over the test range area.

  12. E-waste management and resources recovery in France.

    PubMed

    Vadoudi, Kiyan; Kim, Junbeum; Laratte, Bertrand; Lee, Seung-Jin; Troussier, Nadège

    2015-10-01

    There are various issues of concern regarding electronic waste management, such as the toxicity of hazardous materials and the collection, recycling and recovery of useful resources. To understand the fate of electronic waste after collection and recycling, a products and materials flow analysis should be performed. This is a critical need, as material resources are becoming increasingly scarce and recycling may be able to provide secondary sources for new materials in the future. In this study, we investigate electronic waste systems, specifically the resource recovery or recycling aspects, as well as mapping electronic waste flows based on collection data in France. Approximately 1,588,453 t of new electrical and electronic equipment were sold in the French market in 2010. Of this amount, 430,000 t of electronic waste were collected, with the remaining 1,128,444 t remaining in stock. Furthermore, the total recycled amounts were 354,106 t and 11,396 t, respectively. The main electronic waste materials were ferrous metals (37%), plastic (22%), aluminium (12%), copper (11%) and glass (7%). This study will contribute to developing sustainable electronic waste and resource recycling systems in France. PMID:26283311

  13. E-waste management and resources recovery in France.

    PubMed

    Vadoudi, Kiyan; Kim, Junbeum; Laratte, Bertrand; Lee, Seung-Jin; Troussier, Nadège

    2015-10-01

    There are various issues of concern regarding electronic waste management, such as the toxicity of hazardous materials and the collection, recycling and recovery of useful resources. To understand the fate of electronic waste after collection and recycling, a products and materials flow analysis should be performed. This is a critical need, as material resources are becoming increasingly scarce and recycling may be able to provide secondary sources for new materials in the future. In this study, we investigate electronic waste systems, specifically the resource recovery or recycling aspects, as well as mapping electronic waste flows based on collection data in France. Approximately 1,588,453 t of new electrical and electronic equipment were sold in the French market in 2010. Of this amount, 430,000 t of electronic waste were collected, with the remaining 1,128,444 t remaining in stock. Furthermore, the total recycled amounts were 354,106 t and 11,396 t, respectively. The main electronic waste materials were ferrous metals (37%), plastic (22%), aluminium (12%), copper (11%) and glass (7%). This study will contribute to developing sustainable electronic waste and resource recycling systems in France.

  14. French hormones: progestins and therapeutic variation in France.

    PubMed

    Löwy, Ilana; Weisz, George

    2005-06-01

    Western medicine is seen as universally valid, but in reality it displays a wide range of national and local variability. Our paper focuses on one such case of local variation: the widespread use of progestins in France to treat various pre-menopausal conditions as well as for contraception. The case of progestins allows us to explore how specific styles of research may come to dominate a particular local medical culture, and how they are influenced by changing criteria of scientific validity and wider social relations. We argue that in the 1980s and 1990s a single prestigious research-oriented Parisian hospital service played a dominant role in the transformation of progestins into scientifically validated medical practice. This status was not called seriously into question until recently when foreign research on a different form of hormone therapy suggested that risk was associated with their use. We also propose that both the research around and medical use of progestins in France was shaped by the positive attitude of many French women, including feminists, to hormonal therapies and to the non-surgical specialty most closely associated with hormones, medical gynaecology. PMID:15814185

  15. Obtaining Reimbursement in France and Italy for New Diabetes Products

    PubMed Central

    Schaefer, Elmar; Sonsalla, Jessica

    2015-01-01

    Manufacturers launching next-generation or innovative medical devices in Europe face a very heterogeneous reimbursement landscape, with each country having its own pathways, timing, requirements and success factors. We selected 2 markets for a deeper look into the reimbursement landscape: France, representing a country with central decision making with defined processes, and Italy, which delegates reimbursement decisions to the regional level, resulting in a less transparent approach to reimbursement. Based on our experience in working on various new product launches and analyzing recent reimbursement decisions, we found that payers in both countries do not reward improved next-generation products with incremental reimbursement. Looking at innovations, we observe that manufacturers face a challenging and lengthy process to obtain reimbursement. In addition, requirements and key success factors differ by country: In France, comparative clinical evidence and budget impact very much drive reimbursement decisions in terms of pricing and restrictions, whereas in Italy, regional key opinion leader (KOL) support and additional local observational data are key. PMID:25550411

  16. Neanderthal infant and adult infracranial remains from Marillac (Charente, France).

    PubMed

    Dolores Garralda, María; Maureille, Bruno; Vandermeersch, Bernard

    2014-09-01

    At the site of Marillac, near the Ligonne River in Marillac-le-Franc (Charente, France), a remarkable stratigraphic sequence has yielded a wealth of archaeological information, palaeoenvironmental data, as well as faunal and human remains. Marillac must have been a sinkhole used by Neanderthal groups as a hunting camp during MIS 4 (TL date 57,600 ± 4,600BP), where Quina Mousterian lithics and fragmented bones of reindeer predominate. This article describes three infracranial skeleton fragments. Two of them are from adults and consist of the incomplete shafts of a right radius (Marillac 24) and a left fibula (Marillac 26). The third fragment is the diaphysis of the right femur of an immature individual (Marillac 25), the size and shape of which resembles those from Teshik-Tash and could be assigned to a child of a similar age. The three fossils have been compared with the remains of other Neanderthals or anatomically Modern Humans (AMH). Furthermore, the comparison of the infantile femora, Marillac 25 and Teshik-Tash, with the remains of several European children from the early Middle Ages clearly demonstrates the robustness and rounded shape of both Neanderthal diaphyses. Evidence of peri-mortem manipulations have been identified on all three bones, with spiral fractures, percussion pits and, in the case of the radius and femur, unquestionable cutmarks made with flint implements, probably during defleshing. Traces of periostosis appear on the fibula fragment and on the immature femoral diaphysis, although their aetiology remains unknown.

  17. Vaccine knowledge in students in Paris, France, and surrounding regions

    PubMed Central

    Mellon, Guillaume; Rigal, Laurent; Partouche, Henri; Aoun, Olivier; Jaury, Philippe; Joannard, Nathalie; Guthmann, Jean Paul; Cochereau, Delphine; Caumes, Eric; Bricaire, Francois; Salmon-Céron, Dominique

    2014-01-01

    INTRODUCTION: In France, young adults are legally freed from parental authority at the age of 18 years and are, thus, responsible for their own vaccine record. This young adult population is more frequently exposed to vaccine-preventable infectious diseases. OBJECTIVE: To determine the factors associated with students’ knowledge of the interval between two antitetanus boosters and their report of having up-to-date vaccinations. METHODS: In April 2009, a survey was conducted involving a random sample of students between 18 and 25 years of age eating lunch at university dining facilities in Paris and its suburbs (Ile de France). RESULTS: Among the 677 students approached, 583 agreed to participate. Only 207 (36%) of respondents knew the recommended dosing interval between two doses of tetanus vaccine booster (10 years). The majority of students (69%) reported having up-to-date vaccinations. Declaring having up-to-date vaccinations was significantly associated with having a general practitioner (OR 3.03 [95% CI 1.69 to 5.55]). Health care students were significantly more likely to know the decennial interval between two antitetanus boosters (OR 2 [95% CI 1.28 to 3.25]). Most of responding students (n=519 [89%]) believed that vaccines were very useful. CONCLUSIONS: An overall lack of knowledge of vaccines was observed among this student population. Health care providers, such as GPs and university medical practice staff, who interact with these young individuals have an essential role to promote better vaccination coverage in this population. PMID:25285109

  18. The Canada-France-Hawaii Telescope - Gestation, infancy and future

    NASA Astrophysics Data System (ADS)

    Racine, R.

    1981-12-01

    The development, current status and future potential of the 3.6-m Canada-France-Hawaii Telescope (CFHT), on Mauna Kea are reviewed. The joint project is shown to have arisen from a desire on the part of France beginning in 1965 for an instrument similar to the 3.6-m ESO telescope, in the Northern Hemisphere, and a parallel desire on the part of Canadian astronomers for a large telescope at a location with the best seeing conditions, coupled with the promotion of the Mauna Kea site as a location with clear sky, sensational images, and excellent quality for infrared astronomy. Since the inauguration of the telescope in September 1979, the telescope has been used for 110 projects in 18 months, even as the installation of the coude focus and spectrograph, Reticon detector, and final control software were in progress. Although the CFHT has a potential for high performance in infrared studies, high-dispersion coude spectroscopy, moderate-resolution spectroscopy, stellar photometry, polarimetry or photoelectric spectrophotometry, it is expected that it will prove most useful in imaging applications.

  19. Bishop plays down report on condoms / AIDS in France.

    PubMed

    1996-02-26

    Individual bishops in France and other European countries have argued that condom use can save lives by preventing the spread of HIV. The French Bishops' Conference social commission published a 200-page report which in which agreement was expressed with widespread medical opinion that condom use is the sole and necessary barrier against the sexual spread of HIV. Extensive media coverage ensued and led to Bishop Albert Rouet, the bishop of Poitiers and chairman of the French Bishops' Conference, being interviewed by the Holy See's official radio. In the interview, Bishop Rouet distanced the Roman Catholic Church in France from the report, claiming that the media had exaggerated the issue and that his commission was not bound by the reference. The Vatican remains staunchly opposed to condom use against HIV infection and preaches abstinence outside of marriage and fidelity within marriage as the only true ways to avoid HIV infection. In 1995, the Vatican fired Jacques Gaillot, the former bishop of Evreux in Normandy, for his outspoken endorsement of condom use against HIV.

  20. 10 years of surveillance of human tularaemia in France.

    PubMed

    Mailles, A; Vaillant, V

    2014-11-13

    Tularaemia has been mandatorily notifiable in France since October 2002. The surveillance aims to detect early any infection possibly due to bioterrorism and to follow up disease trends. We report the results of national surveillance from 2002 to 2012. A case is defined as a patient with clinical presentation suggestive of tularaemia and biological confirmation of infection or an epidemiological link with a biologically confirmed case. Clinical, biological and epidemiological data are collected using a standardised notification form. From 2002 to 2012, 433 cases were notified, with a median age of 49 years (range 2 to 95 years) and a male–female sex ratio of 1.8. Most frequent clinical presentations were glandular tularaemia (n=200; 46%) and ulceroglandular tularaemia (n=113; 26%). Most frequent at-risk exposures were handling hares (n=179; 41%) and outdoor leisure exposure to dust aerosols (n=217; 50%). Tick bites were reported by 82 patients (19%). Ten clusters (39 cases) were detected over the 10-year period, as well as a national outbreak during winter 2007/2008. The tularaemia surveillance system is able to detect small clusters as well as major outbreaks. Surveillance data show exposure to dust aerosols during outdoor leisure activities to be a major source of contamination in France.

  1. Eisosomes promote the ability of Sur7 to regulate plasma membrane organization in Candida albicans

    PubMed Central

    Wang, Hong X.; Douglas, Lois M.; Veselá, Petra; Rachel, Reinhard; Malinsky, Jan; Konopka, James B.

    2016-01-01

    The plasma membrane of the fungal pathogen Candida albicans forms a protective barrier that also mediates many processes needed for virulence, including cell wall synthesis, invasive hyphal morphogenesis, and nutrient uptake. Because compartmentalization of the plasma membrane is believed to coordinate these diverse activities, we examined plasma membrane microdomains termed eisosomes or membrane compartment of Can1 (MCC), which correspond to ∼200-nm-long furrows in the plasma membrane. A pil1∆ lsp1∆ mutant failed to form eisosomes and displayed strong defects in plasma membrane organization and morphogenesis, including extensive cell wall invaginations. Mutation of eisosome proteins Slm2, Pkh2, and Pkh3 did not cause similar cell wall defects, although pkh2∆ cells formed chains of furrows and pkh3∆ cells formed wider furrows, identifying novel roles for the Pkh protein kinases in regulating furrows. In contrast, the sur7∆ mutant formed cell wall invaginations similar to those for the pil1∆ lsp1∆ mutant even though it could form eisosomes and furrows. A PH-domain probe revealed that the regulatory lipid phosphatidylinositol 4,5-bisphosphate was enriched at sites of cell wall invaginations in both the sur7∆ and pil1∆ lsp1∆ cells, indicating that this contributes to the defects. The sur7∆ and pil1∆ lsp1∆ mutants displayed differential susceptibility to various types of stress, indicating that they affect overlapping but distinct functions. In support of this, many mutant phenotypes of the pil1∆ lsp1∆ cells were rescued by overexpressing SUR7. These results demonstrate that C. albicans eisosomes promote the ability of Sur7 to regulate plasma membrane organization. PMID:27009204

  2. Artificial snowmaking and potential water conflicts in mountain resorts. The case of Avoriaz (Haute-Savoie, France)

    NASA Astrophysics Data System (ADS)

    Magnier, E.; Reynard, E.

    2012-04-01

    . During winter 2010-2011, insufficient snowfall resulted in large-scale production of artificial snow, thereby considerably weakening the water resource. The poor contribution made by precipitation at the end of the winter and during summer did not enable these reserves to be refilled. In November 2011, reserves were insufficient to start snowmaking production. The lake level was very low and was disturbing the drinking water supply. Without precipitation at the beginning of winter the situation would have been catastrophic for the winter season. In conclusion, this study shows that resource sharing is a risky situation and can cause water deficits punctually. Reference Miquel, G. 2003. Rapport sur la qualité de l'eau et de l'assainissement en France. Office parlementaire d'évaluation des choix scientifiques et technologiques, Paris, 195 p.

  3. In situ and laboratory investigations of fluid flow through an argillaceous formation at different scales of space and time, Tournemire tunnel, southern France

    NASA Astrophysics Data System (ADS)

    Boisson, Jean-Yves; Bertrand, Lucien; Heitz, Jean-François; Golvan, Yann Moreau-Le

    2001-01-01

    In the context of a research and development program on waste disposal, an experimental site (Tournemire tunnel, Aveyron, France) was selected by the French Institute for Nuclear Protection and Safety (IPSN) in order to undertake studies on potential fluid flow at different scales of space and time within a 250-m-thick argillaceous formation. The argillite has a low natural water content ( 3-5%) and very low radii access porosity. Diffusion (tritiated water) coefficients (1×10-12 to 2×10-11 m2/s) and hydraulic conductivities derived from different types of laboratory tests (10-14 to 10-13 m/s) are characteristics of a very low-permeable rock. In situ hydraulic tests (including long-term hydraulic-head measurements) were used to obtain values for hydraulic head and hydraulic conductivity at a scale of 1-10 m (10-13 to 10-11 m/s). Despite uncertainties on these data (due to a scale factor, presence of fissures, and possible artefacts due to hydro-chemo-mechanical coupling), it is expected that fluid flow is essentially governed by diffusion processes. Identification of possible natural flows at larger scales of time and space was investigated using natural isotopic tracers from interstitial fluids. Modelling, based on the deuterium profile along the clay formation and assuming pure diffusion processes, provides estimations of possible flow times. However, lack of knowledge concerning the past geological evolution of the site and the possible role of a fracture network do not permit reduction of uncertainties on these estimations at this stage. Résumé. Dans le cadre de son programme de recherche et développement sur les stockages de déchets, un site expérimental (tunnel de Tournemire, Aveyron, France) a été sélectionné par l'Institut de Protection et Sûreté Nucléaire (IPSN) pour conduire des études sur les possibilités de transferts de fluides à différentes échelles de temps et d'espace au sein d'une formation argileuse de 250 m d'épaisseur. L

  4. 75 FR 69858 - Airworthiness Directives; Eurocopter France (Eurocopter) Model AS332L2 Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-16

    ... 12866; 2. Is not a ``significant rule'' under the DOT Regulatory Policies and Procedures (44 FR 11034... France (Eurocopter) Model AS332L2 Helicopters AGENCY: Federal Aviation Administration (FAA), Department... AS332L2 helicopters have been approved by the aviation authority of France and are approved for...

  5. Corporate Language: The Blind Spot of Language Policy? Reflections on France's Loi Toubon

    ERIC Educational Resources Information Center

    Saulière, Jérôme

    2014-01-01

    This article looks at France's Loi Toubon, which mandates the use of French in private companies, to illustrate how macro-level language planning reaches a dead end if it fails to consider local contexts and involve micro-level agents. The motivations, limitations and contradictions of France's language policy in relation to companies…

  6. Education in France. Bulletin, 1963, No. 33. OE-14091. [Chapter VII - Bibliography

    ERIC Educational Resources Information Center

    Male, George M.

    1963-01-01

    The present bulletin on education in France is another in the Office of Education's long established series on education in other countries. France is of particular interest because of its strong educational traditions and its dedication to democratic principles. In the process of gathering information for this study, the author visited schools in…

  7. What Do We Do with a Difference? France and the Debate over Headscarves in Schools

    ERIC Educational Resources Information Center

    Eshet, Dan

    2008-01-01

    This book focuses on the recent debates surrounding headscarves in public schools in France, where the wearing of an article of clothing became the focus of intense national debate. The book is divided into two parts. Part One, Framing the Discussion, includes the following essays: (1) Essay: Immigration and Integration in Europe (2) France; (3)…

  8. Possible application of the Environmental Relative Moldiness Index in France: A pilot study in Brittany

    EPA Science Inventory

    Our goal was to determine if the US Environmental Relative Moldiness Index (ERMI) scale might have application in France. Twenty homes in Brittany, north western region of France were classified by inspection as “Moldy” or “Non-Moldy”. Dust and air samples were collected (MiTest ...

  9. Educating the People: "Cours d'adultes" and Social Stratification in France, 1830-1870

    ERIC Educational Resources Information Center

    Rowe, Steven E.

    2010-01-01

    This essay examines the formation, operation, and social effects of adult education classes in France during the nineteenth century. These classes were created and operated prior to the formation of France's national education system and were part of the expansion of primary schooling for the working class, or more generally for "the people". The…

  10. From Higher Education to Employment: Inequalities among Ethnic Backgrounds in France

    ERIC Educational Resources Information Center

    Frickey, Alan; Murdoch, Jake; Primon, Jean-Luc

    2006-01-01

    In France, as in many European countries, youth from foreign ethnic backgrounds appear less integrated than those who are accepted as established French citizens into civil society through the educational system and the labor market. Until now, existing research on employment inequalities in France has, for good reasons, concentrated on the large…

  11. 76 FR 11509 - Brass Sheet and Strip From France, Germany, Italy, and Japan

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-02

    ... France, Germany, and Italy (52 FR 6995; Italy amended at 52 FR 11299 (April 8, 1987)). On August 12, 1988... and strip from France, Germany, Italy, and Japan (71 FR 16552). The Commission is now conducting third... recently amended at 74 FR 2847 (January 16, 2009). \\1\\ No response to this request for information...

  12. 77 FR 53844 - Ball Bearings and Parts Thereof From France and Italy: Rescission of Antidumping Duty...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-04

    ... Duty Administrative Reviews and Request for Revocations in Part, 77 FR 40565 (July 10, 2012... International Trade Administration Ball Bearings and Parts Thereof From France and Italy: Rescission of... parts thereof from France and Italy. The period of review is May 1, 2011, through September 14, 2011....

  13. Accreditation or Validation of Prior Experiential Learning: Knowledge and "Savoirs" in France-A Different Perspective?

    ERIC Educational Resources Information Center

    Pouget, Mireille; Osborne, Michael

    2004-01-01

    This article stems from the study of the process and application of Accreditation of Prior Experiential Learning (APEL) in the French higher education system, in France referred to as VAP (Validation des Acquis Professionnels ). The paper seeks to review not only the context in which the concepts underpinning VAP in France have developed, but also…

  14. Reform and Development of Higher Education in Europe: France, The Netherlands, and Poland.

    ERIC Educational Resources Information Center

    United Nations Educational, Scientific, and Cultural Organization, Paris (France).

    This document examines reform and development of higher education in France, Poland, and the Netherlands. Part I examines facets of higher education in France including the tasks of the universities: research, teaching, and development of higher training and continuing education; present structures of French universities; increase in student…

  15. Communication Patterns and Intellectual Traditions in Educational Sciences: France and Germany.

    ERIC Educational Resources Information Center

    Schriewer, Jurgen; Keiner, Edwin

    1991-01-01

    Examines patterns of institutional organization and communication in education in France and Germany. The science of education is autonomous and philosophically oriented in Germany but is intertwined with sociology, psychology, and other social sciences and is positivistic in nature in France. Overlap between the cognitive textures of the French…

  16. New introductions of enterovirus 71 subgenogroup C4 strains, France, 2012.

    PubMed

    Schuffenecker, Isabelle; Henquell, Cécile; Mirand, Audrey; Coste-Burel, Marianne; Marque-Juillet, Stéphanie; Desbois, Delphine; Lagathu, Gisèle; Bornebusch, Laure; Bailly, Jean-Luc; Lina, Bruno

    2014-08-01

    In France during 2012, human enterovirus 71 (EV-A71) subgenogroup C4 strains were detected in 4 children hospitalized for neonatal fever or meningitis. Phylogenetic analysis showed novel and independent EV-A71 introductions, presumably from China, and suggested circulation of C4 strains throughout France. This observation emphasizes the need for monitoring EV-A71 infections in Europe.

  17. Economic Analysis of Grain Production in France. Staff Report No. AGES880202.

    ERIC Educational Resources Information Center

    Liapis, Peter S.

    A study analyzed grain production in France, the major grain producer in the European Community and one of the leading producers in the world. France is also a major grain exporter and thus competes with the United States in world markets. The United States is pursuing a policy of lower world prices to regain market share. Large grain surpluses in…

  18. 75 FR 42380 - Revocation of Antidumping Duty Order on Sorbitol From France

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-21

    ... from France. See Initiation of Five-year (``Sunset'') Review, 74 FR 31412 (July 1, 2009). Pursuant to... United States within a reasonably foreseeable time. Sorbitol From France; Determination, 75 FR 39277... Order, 47 FR 15391 (April 9, 1982). On June 29, 1984, the order was revoked, in part. See Sorbitol...

  19. 77 FR 19642 - Low Enriched Uranium From France: Final Results of Antidumping Duty Changed Circumstances Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-02

    ... Uranium From France, 67 FR 6680 (February 13, 2002). As for evaluating AREVA's request, the Department... Circumstances Review, 77 FR 7128 (February 10, 2012) (Preliminary Results). DATES: Effective Date: April 2, 2012... International Trade Administration Low Enriched Uranium From France: Final Results of Antidumping Duty...

  20. 77 FR 1059 - Low Enriched Uranium From France: Initiation of Antidumping Duty Changed Circumstances Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-09

    ... International Trade Administration Low Enriched Uranium From France: Initiation of Antidumping Duty Changed... review of the antidumping duty order on low enriched uranium (LEU) from France with respect to Eurodif S... deadline for re-exporting the LEU entry at issue. \\1\\ See Letter from AREVA, ``Low Enriched Uranium...

  1. Severe Ketoalkalosis as Initial Presentation of Imported Human Rabies in France

    PubMed Central

    Contou, Damien; Dacheux, Laurent; Bendib, Inès; Jolivet, Sarah; Rodriguez, Christophe; Tomberli, Françoise; Cleret de Langavant, Laurent; Lavenir, Rachel; Lepelletier, Anthony; Larrous, Florence; Troupin, Cécile; Bourhy, Hervé

    2015-01-01

    We report a patient with an unusual initial metabolic presentation of imported human rabies who became symptomatic within 2 weeks of returning from Mali to France. This is the single case of imported human rabies identified in France within the past 11 years and the first report of viral RNA in bronchial secretions. PMID:25854482

  2. From Sun King to Royal Twilight: Painting in Eighteenth Century France from the Musee Picardie, Amiens.

    ERIC Educational Resources Information Center

    Johnson, Mark M.

    2000-01-01

    Focuses on the traveling exhibition from the Musee de Picardie in Amiens, France, called "From the Sun King to the Royal Twilight: Painting in Eighteenth Century France," that provides an overview of French paintings from the reign of Louis IV to the fall of the monarchy. (CMK)

  3. [First-aid in France. Current situation and future perspectives].

    PubMed

    Larcan, Alain; Julien, Henri

    2010-06-01

    First-aid--treatment aimed at enabling a victim to survive pending the arrival of qualified medical support--is less well developed in France than in many other industrialized countries, especially among the general public. The current status of first-aid in France is paradoxical: schooling is free and obligatory, the ambulance service and emergency services are of the highest quality, but the general public are too often passive and unknowledgeable when faced with an emergency situation. This situation is due to several factors, including the complexity of first-aid training and regulations, the involvement of too many public bodies, the legal liability of the first-aider, and a lack of ongoing training. The French National Academy of Medicine recommends 8 measures to improve this situation: Provide a legal definition of first-aid: "a set of recognized measures aimed, in an emergency setting, at preserving the physical and psychological integrity of the victim of an accident or illness, notably pending the arrival of professional medical assistance". Waive, as in many other countries, civil and legal responsibility for the non professional first-aider, except in case of clear negligence. Reinforce the organization of first-aid in France in order to monitor the number and quality of first-aiders, and to ensure theoretical and pedagogic research; create a communications department capable of supporting and promoting first-aid. Improve access to first-aid training by increasing the number of situations in which it is obligatory (driving tuition, school and university examinations, group responsibility, at-risk practices), by providing financial assistance for certain groups, and by ensuring routine training at school, in the armed forces, and in the workplace. Create a progressive and integrated citizen first-aid training course with individual modules, ensuring that first-aiders update and perfect their knowledge throughout life. Soften pedagogic rules and shorten

  4. Exposure to indoor tanning in France: a population based study

    PubMed Central

    2013-01-01

    Background Tanning lamp sessions have increased in Europe in recent years. Recent epidemiological studies have confirmed a proven link between melanoma and artificial UV exposure. However, in France, little information is available to determine the exposure of the population. This article presents the results from the ‘Baromètre cancer 2010’ concerning the proportion of users exposed to artificial UV radiation in France, their characteristics and level of information on the risks associated. Methods A two stage random sampling telephone survey assisted by CATI system (household, individual) was performed from 3 April 2010 to 7 August 2010 on a sample of 3,359 people aged 15 to 75 years old. Results In 2010, 13.4% of the French population reported to have tanning lamp sessions at least once in their lifetime and 3.5% of the total population reported the use of artificial UV radiation over the last twelve months. Exposure over the last twelve months is most commonly seen among females (5.0%) and young population between 20–25 years old (9.6%). In addition, 3.5% of those under 18 years report having attended UV booths at least once during their lifetime even though they are forbidden to minors. Moreover, more than one the third of users reported more than 10 exposures within a year. The places of exposure cited most often were beauty salons (50%) and tanning centers (46%). Only 49.2% of those surveyed felt that they were well informed on the risks of cancer associated with UV booths. Furthermore, the population was found to have misconceptions about artificial UV radiation. One quarter of the population, believe that artificial UV radiation use before vacation protects the skin from sunburn. Conclusions This first study on artificial UV radiation exposure in France has better quantified and characterized the users. It has also defined the state of knowledge and the perception of risk by the general French population. This work will contribute to determine

  5. [First-aid in France. Current situation and future perspectives].

    PubMed

    Larcan, Alain; Julien, Henri

    2010-06-01

    First-aid--treatment aimed at enabling a victim to survive pending the arrival of qualified medical support--is less well developed in France than in many other industrialized countries, especially among the general public. The current status of first-aid in France is paradoxical: schooling is free and obligatory, the ambulance service and emergency services are of the highest quality, but the general public are too often passive and unknowledgeable when faced with an emergency situation. This situation is due to several factors, including the complexity of first-aid training and regulations, the involvement of too many public bodies, the legal liability of the first-aider, and a lack of ongoing training. The French National Academy of Medicine recommends 8 measures to improve this situation: Provide a legal definition of first-aid: "a set of recognized measures aimed, in an emergency setting, at preserving the physical and psychological integrity of the victim of an accident or illness, notably pending the arrival of professional medical assistance". Waive, as in many other countries, civil and legal responsibility for the non professional first-aider, except in case of clear negligence. Reinforce the organization of first-aid in France in order to monitor the number and quality of first-aiders, and to ensure theoretical and pedagogic research; create a communications department capable of supporting and promoting first-aid. Improve access to first-aid training by increasing the number of situations in which it is obligatory (driving tuition, school and university examinations, group responsibility, at-risk practices), by providing financial assistance for certain groups, and by ensuring routine training at school, in the armed forces, and in the workplace. Create a progressive and integrated citizen first-aid training course with individual modules, ensuring that first-aiders update and perfect their knowledge throughout life. Soften pedagogic rules and shorten

  6. Influence des effets de température quasi-statiques du premier ordre sur les dispositifs à ondes de surface transverses sur sillons gravés

    NASA Astrophysics Data System (ADS)

    Ballandras, S.; Gavignet, E.; Bigler, E.

    1995-02-01

    The present study is devoted to the theoretical calculation of the first order quasi-static temperature coefficient of surface transverse waves which can propagate under shallow groove gratings. The model presented here associates an analytical description of non-perturbed surface transverse waves on an anisotropic substrate developed by Auld and Tiersten's perturbation method. This approach has been implemented in the case of quartz delay lines corrugated with rectangular grooves. It is shown that singly rotated quartz cuts can be theoretically found exhibiting a first-order temperature coefficient close to zero. The sensitivity of this coefficient versus the groove depth is also theoretically demonstrated. La présente étude consiste à calculer le coefficient de température du premier ordre d'un résonateur à ondes transverses de surface se propageant sous un réseau de sillons gravés de forme quelconque. Ce calcul fait intervenir un modèle analytique de propagation des ondes sur un substrat anisotrope développé par Auld et une méthode de perturbation mise au point par Tiersten. Cette approche théorique a été mise en oeuvre pour traiter le cas des dispositifs à sillons gravés de profil rectangulaire sur quartz. On montre ainsi qu'il existe des coupes de quartz à simple rotation présentant un coefficient de température du premier ordre théorique proche de zéro. L'influence de la profondeur de gravure des sillons sur ce coefficient est également mise en évidence théoriquement.

  7. Évolution des lignes directrices sur le traitement de la dyslipidémie

    PubMed Central

    John Bosomworth, N.

    2014-01-01

    Résumé Objectif Comprendre comment les nouvelles lignes directrices sur la prise en charge du risque cardiovasculaire publiées par l’American Heart Association et l’American College of Cardiology (AHA-ACC) peuvent être interprétées et utilisées dans le contexte canadien. Sources des données Les lignes directrices de l’AHA-ACC ont été examinées, de même que toutes les références. Des recherches indépendantes dans PubMed ont été effectuées pour inclure l’ajout aux statines d’autres antihyperlipidémiants et l’emploi de calculatrices médicales visant à aider le patient à comprendre. Message principal Les nouvelles lignes directrices de l’AHA-ACC s’appuient sur les meilleures données probantes disponibles actuellement en matière de traitement de la dyslipidémie. Cela inclut le risque cardiovasculaire (CV) sur 10 ans comme seuil thérapeutique au lieu du taux de cholestérol des lipoprotéines de faible densité, de même que l’abandon des cibles thérapeutiques de lipoprotéines de faible densité. On met de plus en plus l’accent sur les interventions alimentaires et l’exercice, avec l’amorce d’un effort pour quantifier l’effet de ces interventions. Les statines constituent la principale intervention pharmacologique, et l’ajout d’autres médicaments pour accentuer la baisse lipidique n’est plus recommandé. En ce qui concerne l’application au Canada, les tables de risque de Framingham sont plus appropriées pour évaluer le risque que les équations de cohortes regroupées utilisées aux États-Unis. Les calculatrices du risque de maladie cardiovasculaire (MCV) devraient contenir de l’information sur l’âge cardiovasculaire et devraient pouvoir illustrer le risque et les interventions de rechange afin d’aider le patient à comprendre et de favoriser la prise de décision éclairée. Conclusion L’attention sur les meilleures données probantes concernant le risque CV peut simplifier le traitement de la

  8. Structural investigations in the Massif-Central, France

    NASA Technical Reports Server (NTRS)

    Scanvic, J. Y.

    1974-01-01

    This survey covered the French Massif-Central (where crystalline and volcanic rocks outcrop) and its surrounding sedimentaries, Bassin de Paris, Bassin d'Aquitaine and Rhodanian valley. One objective was the mapping of fracturing and the surveying of its relationship with known ore deposits. During this survey it was found that ERTS imagery outlines lithology in some sedimentary basins. On the other hand, in a basement area, under temperature climate conditions, lithology is rarely expressed. These observations can be related to the fact that band 5 gives excellent results above sedimentary basins in France and generally band 7 is the most useful in a basement area. Several examples show clearly the value of ERTS imagery for mapping linear features and circular structures. All the main fractures are identified with the exception of new ones found both in sedimentaries and basement areas. Other interesting findings concern sun elevation which, stereoscopic effect not being possible, simulates relief in a better way under certain conditions.

  9. Toscana virus infections: a case series from France.

    PubMed

    Dupouey, J; Bichaud, L; Ninove, L; Zandotti, C; Thirion-Perrier, L; de Lamballerie, X; Charrel, R N

    2014-03-01

    Toscana virus (TOSV) is a neglected sandfly-borne pathogen in Mediterranean countries. Although discovered four decades ago, articles that describe the clinical aspects are scarce and consist mostly of case reports, with few series of cases. We studied retrospectively symptomatic TOSV infections in patients hospitalized in Marseille (France) from 2004 to 2011. Seventeen patients were classified as probable or confirmed cases. Fourteen cases (82%) occurred between June and September, and 3 cases in March, April and November. Two cases were potentially imported from Croatia and Tuscany. All patients presented with fever and neurological signs were observed such as aseptic meningitis (n = 6), muscular symptoms (n = 3), or encephalitis (n = 4). The outcome was always favorable. At the acute stage, anti TOSV IgM were observed in 14/17 patients, neutralization tests were positive for 3/8 patients, and RT-PCR confirmed TOSV infections in 5/8 CSF specimens.

  10. New digital circuits at Thomson semiconductor in France

    NASA Astrophysics Data System (ADS)

    Dellamussia, J. P.

    1985-11-01

    DCS, Thomson Semiconductors' Semi-Standard Circuits Department, has just announced a CMOS gate array with up to 4,200 gates, standard cells, and a unique 900-component, 3 GHz linear gate array. All of Thomson's gate arrays are supported by Daisy, Valid and Mentor workstations. These are the first fruits of a reorganization begun several months ago to distance the department from the actual design and manufacture of integrated circuits, making it more of an archestrator among customers, workstation manufacturers, independent designers and the various Thomson Semiconductors division. Thomson Semiconductors' silicon sales based on DCS contracts totaled 25,000,000 Frances in 1984. This figure should be double in 1985. Thomson Semiconductors plans to offer 120 new integrated circuits this year, twice the number available in 1984. At the same time, the Munich design center and the American subsidiary, VSI, should open new markets in 1985, bringing exports to an estimated 30 percent of sales.

  11. The Rank-Ferenczi relationship, as seen from France.

    PubMed

    Lugrin, Yves

    2012-12-01

    Seen from France, where Rank's "American" work is not well known, the Rank-Ferenczi relationship does not allow to state that the two learned colleagues were the best friends. Rank met Ferenczi in 1908, but their most valuable and fruitful working relationship is limited to the 1922-1924 time period. Their working relationship must be read in light of the unique transference links of each to Freud, and in light of the tormented history of the analytic movement, especially after the First World War. The sensible reader will not forget that after the fast extinction of their short collaboration they continued their own works in their own ways, Otto Rank in Paris and in America and Sándor Ferenczi in Budapest. No more friends, nor enemies, but both, in a different style, brave and creative analysts.

  12. Trend of heat flow in france: relation with deep structures

    NASA Astrophysics Data System (ADS)

    Vasseur, Guy; Nouri, Yamina; Groupe Fluxchaf

    1980-06-01

    The trend of heat flow over France is discussed using both direct measurements at equilibrium in boreholes and file data. The two types of data are found to be in agreement. They exhibit high heat flow values over the Massif Central and the Vosges. An E-W cross section across the Massif Central allows us to observe the relationship between the high heat flow values, the thinning of the crust and the uprising of the asthenosphere deduced from seismic and gravity measurements. High heat flow values could be explained using a cinematic model where upward convection occurs in the upper mantle for a period of 40 m.y. with a vertical velocity reaching 5 mm/y.

  13. [Needs and financing of radiotherapy in France and Europe].

    PubMed

    Defourny, N; Lievens, Y

    2016-10-01

    Access to high-quality and safe radiotherapy is a prerequisite to assure optimal oncology care in a multidisciplinary environment. In view of supporting long-term radiotherapy planning, actual and predicted radiotherapy needs should be put in context of the nowadays' available resources. The present article reviews the existing data on radiotherapy resources and needs, along with the prevailing reimbursement systems in the different European countries, with a specific emphasis on France. It describes potential incentives of different financing systems on clinical practice and highlights how knowledge of the cost of radiotherapy treatments, by indication and technique, is essential to support correct reimbursement, hence access to radiotherapy. It is expected that such data will help national professional and scientific radiotherapy societies across Europe in their negotiations with policy makers, with the ultimate aim to make radiotherapy accessible to all cancer patients who need it, now and in the decades to come.

  14. Automation under suspicion--case flight AF-447 Air France.

    PubMed

    Martins, Edgard; Soares, Marcelo

    2012-01-01

    The probes allow the pilot to control the aircraft speed was essential to the balance of the flight. Opinions of experts who claim that "the design of the plane would have exercised a not inconsiderable role in the occurrence of a disaster." These messages revealed a series of important operating errors in a zone of turbulence, "making the plane uncontrollable, leading to a rapid depressurization device, according to these reports. A lawsuit in Toulouse and in Brazil aims to recognition of the liability of Air France and Airbus not insignificant role in the design and operation of the aircraft in the event of catastrophe. Opinions are taken from senior pilots that no commercial aviation training for certain situations abnormal flight that, if realized, could have influenced the pilots of the AF-447 to remove the plane's fatal dive show what experiments performed in simulators for military pilots, who are permanently subject to critical flight situations.

  15. [Intraosseous vascular access, a technic previously underestimated in France].

    PubMed

    Oriot, D; Cardona, J; Berthier, M; Nasimi, A; Boussemart, T

    1994-07-01

    Intraosseous vascular access is a simple and very efficient technique for fluid and drug administration in any pediatric emergencies where the intravenous route is impossible or inadequate. Yet it remains unrecognized in France. Its pharmacokinetics is close to that of peripheral intravenous route, but it allows much greater infusion flow rates. In pediatric resuscitation it must be considered as the number one technique of intravascular access in infants, and rapidly as the first alternative after failure of attempt of intravenous route in children under 6. Provided that the technique is performed with careful asepsis, the risk of infectious complications is very low. However the intraosseous route must remain a transitory vascular access, and has to be stopped as soon as possible, its use never exceeding 24 hours. PMID:7987470

  16. The Rank-Ferenczi relationship, as seen from France.

    PubMed

    Lugrin, Yves

    2012-12-01

    Seen from France, where Rank's "American" work is not well known, the Rank-Ferenczi relationship does not allow to state that the two learned colleagues were the best friends. Rank met Ferenczi in 1908, but their most valuable and fruitful working relationship is limited to the 1922-1924 time period. Their working relationship must be read in light of the unique transference links of each to Freud, and in light of the tormented history of the analytic movement, especially after the First World War. The sensible reader will not forget that after the fast extinction of their short collaboration they continued their own works in their own ways, Otto Rank in Paris and in America and Sándor Ferenczi in Budapest. No more friends, nor enemies, but both, in a different style, brave and creative analysts. PMID:23175027

  17. Education and research in medical optronics in France

    NASA Astrophysics Data System (ADS)

    Demongeot, Jacques; Fleute, M.; Herve, T.; Lavallee, Stephane

    2000-06-01

    First we present here the main post-graduate courses proposed in France both for physicians and engineers in medical optronics. After we explain which medical domains are concerned by this teaching, essentially computer assisted surgery, telemedicine and functional exploration. Then we show the main research axes in these fields, in which new jobs have to be invented and new educational approaches have to be prepared in order to satisfy the demand coming both from hospitals (mainly referent hospitals) and from industry (essentially medical imaging and instrumentation companies). Finally we will conclude that medical optronics is an important step in an entire chain of acquisition and processing of medical data, capable to create the medical knowledge a surgeon or a physician needs for diagnosis or therapy purposes. Optimizing the teaching of medical optronics needs a complete integration from acquiring to modeling the medical reality. This tendency to give a holistic education in medical imaging and instrumentation is called `Model driven Acquisition' learning.

  18. Surveillance of gastrointestinal disease in France using drug sales data.

    PubMed

    Pivette, Mathilde; Mueller, Judith E; Crépey, Pascal; Bar-Hen, Avner

    2014-09-01

    Drug sales data have increasingly been used for disease surveillance during recent years. Our objective was to assess the value of drug sales data as an operational early detection tool for gastroenteritis epidemics at national and regional level in France. For the period 2008-2013, we compared temporal trends of drug sales for the treatment of gastroenteritis with trends of cases reported by a Sentinel Network of general practitioners. We benchmarked detection models to select the one with the best sensitivity, false alert proportion and timeliness, and developed a prospective framework to assess the operational performance of the system. Drug sales data allowed the detection of seasonal gastrointestinal epidemics occurring in winter with a distinction between prescribed and non-prescribed drugs. Sales of non-prescribed drugs allowed epidemic detection on average 2.25 weeks earlier than Sentinel data. These results confirm the value of drug sales data for real-time monitoring of gastroenteritis epidemic activity. PMID:25240898

  19. Fire occurrence prediction in the Mediterranean: Application to Southern France

    NASA Astrophysics Data System (ADS)

    Papakosta, Panagiota; Öster, Jan; Scherb, Anke; Straub, Daniel

    2013-04-01

    The areas that extend in the Mediterranean basin have a long fire history. The climatic conditions of wet winters and long hot drying summers support seasonal fire events, mainly ignited by humans. Extended land fragmentation hinders fire spread, but seasonal winds (e.g. Mistral in South France or Meltemia in Greece) can drive fire events to become uncontrollable fires with severe impacts to humans and the environment [1]. Prediction models in these areas should incorporate both natural and anthropogenic factors. Several indices have been developed worldwide to express fire weather conditions. The Canadian Fire Weather Index (FWI) is currently adapted by many countries in Europe due to the easily observable input weather parameters (temperature, wind speed, relative humidity, precipitation) and the easy-to-implement algorithms of the Canadian formulation describing fuel moisture relations [2],[3]. Human influence can be expressed directly by human presence (e.g. population density) or indirectly by proxy indicators (e.g. street density [4], land cover type). The random nature of fire occurrences and the uncertainties associated with the influencing factors motivate probabilistic prediction models. The aim of this study is to develop a prediction model of fire occurrence probability under natural and anthropogenic influence in Southern France and to compare it with earlier developed predictions in other Mediterranean areas [5]. Fire occurrence is modeled as a Poisson process. Two interpolation methods (Kriging and Inverse Distance Weighting) are used to interpolate daily weather observations from weather stations to a 1 km² spatial grid and their results are compared. Poisson regression estimates the parameters of the model and the resulting daily predictions are provided in terms of maps displaying fire occurrence rates. The model is applied to the regions Provence-Alpes-Côtes D'Azur und Languedoc-Roussillon in the South of France. Weather data are obtained from

  20. [Medical certificates and the new firearm regulation in France].

    PubMed

    Bouvet, Renaud; Baert, Alain; Le Gueut, Mariannick

    2015-03-01

    France has adopted a new firearms regulation. Firearms are now classified into four categories (A, B, C, and D). The administrative procedure for acquisition and possession of firearms of categories B and C requires medical advice. The medical certificate must be dated less than a month, and detail a state of health compatible with the acquisition and possession of a firearm. There are no guidelines mentioning the conditions that can lead to incompatibility. Compatibility does not apply to the handling and use of the firearm. If the applicant is undergoing or has undergone treatment in a psychiatric institution, he must also produce a medical certificate issued by a psychiatrist. The hunting license application requires a medical certificate mentioning a state of physical and mental health compatible with the possession of a firearm. Its validity is acquired for life. The practice of shooting sports or skeet requires an annual medical certificate of non-cons in reference to the rules of sports federations.

  1. Cloud Height Maps for Hurricanes Frances and Ivan

    NASA Technical Reports Server (NTRS)

    2004-01-01

    NASA's Multi-angle Imaging SpectroRadiometer (MISR) captured these images and cloud-top height retrievals of Hurricane Frances on September 4, 2004, when the eye sat just off the coast of eastern Florida, and Hurricane Ivan on September 5th, after this cyclone had devastated Grenada and was heading toward the central and western Caribbean. Hurricane Frances made landfall in the early hours of September 5, and was downgraded to Tropical Storm status as it swept inland through the Florida panhandle and continued northward. On the heels of Frances is Hurricane Ivan, which is on record as the strongest tropical cyclone to form at such a low latitude in the Atlantic, and was the most powerful hurricane to have hit the Caribbean in nearly a decade.

    The ability of forecasters to predict the intensity and amount of rainfall associated with hurricanes still requires improvement, especially on the 24 to 48 hour timescale vital for disaster planning. To improve the operational models used to make hurricane forecasts, scientists need to better understand the multi-scale interactions at the cloud, mesoscale and synoptic scales that lead to hurricane intensification and dissipation, and the various physical processes that affect hurricane intensity and rainfall distributions. Because these uncertainties with regard to how to represent cloud processes still exist, it is vital that the model findings be evaluated against hurricane observations whenever possible. Two-dimensional maps of cloud height such as those shown here offer an unprecedented opportunity for comparing simulated cloud fields against actual hurricane observations.

    The left-hand panel in each image pair is a natural color view from MISR's nadir camera. The right-hand panels are cloud-top height retrievals produced by automated computer recognition of the distinctive spatial features between images acquired at different view angles. These results indicate that at the time that these images were

  2. [Needs and financing of radiotherapy in France and Europe].

    PubMed

    Defourny, N; Lievens, Y

    2016-10-01

    Access to high-quality and safe radiotherapy is a prerequisite to assure optimal oncology care in a multidisciplinary environment. In view of supporting long-term radiotherapy planning, actual and predicted radiotherapy needs should be put in context of the nowadays' available resources. The present article reviews the existing data on radiotherapy resources and needs, along with the prevailing reimbursement systems in the different European countries, with a specific emphasis on France. It describes potential incentives of different financing systems on clinical practice and highlights how knowledge of the cost of radiotherapy treatments, by indication and technique, is essential to support correct reimbursement, hence access to radiotherapy. It is expected that such data will help national professional and scientific radiotherapy societies across Europe in their negotiations with policy makers, with the ultimate aim to make radiotherapy accessible to all cancer patients who need it, now and in the decades to come. PMID:27599682

  3. Statistical analysis of Nomao customer votes for spots of France

    NASA Astrophysics Data System (ADS)

    Pálovics, Róbert; Daróczy, Bálint; Benczúr, András; Pap, Julia; Ermann, Leonardo; Phan, Samuel; Chepelianskii, Alexei D.; Shepelyansky, Dima L.

    2015-08-01

    We investigate the statistical properties of votes of customers for spots of France collected by the startup company Nomao. The frequencies of votes per spot and per customer are characterized by a power law distribution which remains stable on a time scale of a decade when the number of votes is varied by almost two orders of magnitude. Using the computer science methods we explore the spectrum and the eigenvalues of a matrix containing user ratings to geolocalized items. Eigenvalues nicely map to large towns and regions but show certain level of instability as we modify the interpretation of the underlying matrix. We evaluate imputation strategies that provide improved prediction performance by reaching geographically smooth eigenvectors. We point on possible links between distribution of votes and the phenomenon of self-organized criticality.

  4. Preparing the future of astronomy PhDs in France

    NASA Astrophysics Data System (ADS)

    Boissier, S.; Buat, V.; Cambresy, L.

    2015-12-01

    The numbers of doctors in astronomy formed in France has been increasing for 15 years, a time during which the number of openings for permanent positions has remained constant. As it is well known by the young generations, the pressure on the research position is high, putting many post-doctoral researchers in difficult situations for up to 10 years after their defence. We have to prepare students and post-doctoral researchers to maximize their chances for both academia and the private sector. In this spirit, the 2015 SF2A conference included a lunch meeting with former members of hiring committee and a workshop on the valorization of the astronomy thesis. We believe awareness of both young and senior researchers is important to provide PhDs with a robust background and modern methods, valuable in their future, whichever it is.

  5. Testate amoebae from a cretaceous forest floor microbiocoenosis of france.

    PubMed

    Schmidt, Alexander R; Girard, Vincent; Perrichot, Vincent; Schönborn, Wilfried

    2010-01-01

    Amber-preserved shells of testate amoebae often provide as many diagnostic features as the tests of modern taxa. Most of these well-preserved microfossils are morphologically assignable to modern species indicating either evolutionary stasis or convergent evolution. Here we describe two Lower Cretaceous testate amoebae that are clearly distinguishable from modern species. Centropyxis perforata n. sp. and Leptochlamys galippei n. sp. possessed perforate shells that were previously unknown in these genera. They are preserved in highly fossiliferous amber pieces from the Upper Albian (ca. 100 million years old) of Archingeay/Les Nouillers (Charente-Maritime, southwestern France). Syninclusions of soil and litter dwelling arthropods and microorganisms indicate a limnetic-terrestrial microhabitat at the floor of a coastal conifer forest.

  6. Market access pathways for cell therapies in France

    PubMed Central

    Rémuzat, Cécile; Toumi, Mondher; Jørgensen, Jesper; Kefalas, Panos

    2015-01-01

    Introduction and objective Cell therapies can be classified into three main categories of products: advanced therapy medicinal products (ATMPs), ATMPs prepared on a non-routine basis (hospital exemptions), and minimally manipulated cells. Despite the benefits that cell therapies can bring to patients, they are subject to complex pathways to reach the market in France. The objective of this study was to identify and describe routes to market access for cell therapies in France and how these vary by regulatory status. Methodology The research was structured following five main steps: (1) identification of the French regulatory framework for cell therapies; (2) identification of the health products categorised as cell therapies in France; (3) mapping of the market access pathways per category of cell therapy; (4) validation of findings by interviewing experts; and (5) development of a roadmap summarising market access pathways for cell therapies in France. The secondary research methodology included a comprehensive literature review conducted on websites of French public health institutions, complemented by a research for peer-reviewed articles, abstracts, and grey literature. Results Different market access pathways are possible depending on the cell therapy category. For ATMPs, market access pathways depend on the licensing status of the therapy. Licensed ATMPs followed the same market access pathways as ‘conventional’ pharmaceuticals, whereas not-yet-licensed ATMPs can be funded via a specific financial allowance under the framework of a Temporary Authorisation for Use procedure or various research programmes. For new ATMPs that are associated with a separate medical device (not considered as ‘combined ATMPs’) or associated with a new medical procedure, additional pathways will apply for the medical device and/or medical procedure to be reimbursed in the ambulatory settings or at hospital. The most likely funding option for ATMPs prepared on a non

  7. Archaeomagnetic Study performed on Early Medieval Buildings from western France

    NASA Astrophysics Data System (ADS)

    Chauvin, A.; Lanos, P.; Dufresne, P.; Blain, S.; Guibert, P.; Oberlin, C.; Sapin, C.

    2009-05-01

    A multiple dating study, involving a collaboration between specialists of dating techniques (thermoluminescence (TL) and radiocarbon), historians of art and archaeologists, has been carried out on several early medieval buildings from western France. The early medieval period is not well known especially in France where there is a lack of visible evidence that identifies pre-Romanesque architecture. The majority of buildings to have survived from this period are religious ones, considered important enough to be made of strong, non-perishable material such as stone or brick, as for example the churches of Notre-Dame-sous- Terre in the Mont-Saint-Michel or St Martin in Angers. Due to their significance in architectural history, it is imperative to position them accurately in the chronology of the history of art. Bricks are often used to build up round-headed arches or to reinforce the frame of a wall with bonding courses in those churches. TL dating and archeomagnetic analysis were performed on cores drilled within bricks while radiocarbon dating were undertaken on coals found within mortars. In order to increase the number of data during the early Middle Ages, archeointensity determinations using the classical Thellier technique with anisotropy of thermal remanence and cooling rate corrections were performed. Archaeomagnetic directions were used to recognize the firing position of bricsk during manufacture. Reliable and precise ages were obtained on the church Notre-Dame-sous-Terre; they indicate two phases of building in 950±50AD and 990±50AD. Mean archeointensities obtained on 17 (21) samples from the first (second) phases appears very closed 69.1±1.2 and 68.3±1.6 microTesla. Ages and archeomagnetic results obtained on 4 other sites will be presented and compared to the available data in western Europe.

  8. [Specialized training in geriatric psychiatry during residency in France].

    PubMed

    Lepetit, Alexis; Lavigne, Benjamin; Legros, Emilie; Herrmann, Mathieu; Sebbane, Déborah

    2014-09-01

    Aging of the population is a growing concern in developed countries. Therefore, geriatric psychiatry has gradually emerged from general psychiatry. Many names have been proposed to term this sub-specialty: old age psychiatry (OAP), psychogeriatrics, geropsychiatry. A working group of the French federation of psychiatric trainees (AFFEP) set up an inventory of the theoretical instruction and clinical practice of OAP during the training of psychiatrists in France. Methods. A survey of both academic teaching and practical training for OAP was carried out in the 28 local AFFEP representatives of every French medical residency district, including overseas. We assessed the supply of general courses and seminars devoted to OAP during the training of French residents in psychiatry, and the offer of university or inter-university degrees as well as the possibility of specialized internship in every residency district. Results. 96% of French medical residency districts offered general courses of OAP with a mean volume of 11.5 hours along the four years of psychiatric training in France. Fifty percent of medical residency districts proposed at least one seminar devoted to OAP. Half of medical residency districts also offer a specialized university or inter-university degree. Concerning clinical practice, 86% of medical residency districts had one internship dedicated to OAP, in 39% of cases in teaching hospitals. Conclusion. Nationwide, there is an overall effort to make OAP available to French psychiatric residents by general courses and internship, but some disparity appeared in academic teaching (i.e. offering seminars and university/inter-university degrees) according to various residency districts.

  9. FVCOM model estimate of the location of Air France 447

    NASA Astrophysics Data System (ADS)

    Chen, Changsheng; Limeburner, Richard; Gao, Guoping; Xu, Qichun; Qi, Jianhua; Xue, Pengfei; Lai, Zhigang; Lin, Huichan; Beardsley, Robert; Owens, Breck; Carlson, Barry

    2012-06-01

    On June 1, 2009, Air France AF447 disappeared in the Equatorial Atlantic Ocean en route from Rio de Janeiro, Brazil, to Paris, France. On June 6-19, 2009, bodies and debris from the aircraft were recovered floating in the equatorial ocean. This paper describes efforts on using the global-local nested finite volume community ocean model (FVCOM) to model reversely the tracks of bodies and debris back to the time of the crash and to help searchers locate the cockpit voice and flight data recorders and learn why this tragic accident occurred. To validate the reliability and reality of FVCOM, eight surface drifters were deployed by the French Bureau d'Enquêtes et d'Analyses pour la sécurité de l'aviation civile (BEA) near the last known position in early June 2010 for a period of 3 weeks. These drifter data were used to optimize the spatial and temporal correlation scales of the adaptive sampling data assimilation method of FVCOM. Applying an optimized FVCOM system to assimilate all available drifter- and float-tracking-derived currents in May-June 2009 under three different wind conditions, we reproduced the June 2009 current fields in the area near the LKP and used these fields to reversely track bodies and debris from locations where they were found to the time when the crash occurred. Possible locations for the crashed plane were suggested based on our model results and were made available to the French investigators and the Woods Hole Oceanographic Institution REMUS autonomous underwater vehicle Operations Group who successfully located the aircraft debris field in April 2011 on the seafloor at a depth of 3,900 m.

  10. Coalbed methane exploration in the Lorraine Basin, France

    SciTech Connect

    Michaud, B.; Briens, F.; Girdler, D.

    1995-08-01

    DuPont Conoco Hydrocarbures has been involved in a Coalbed Methane (CBM) project in France since 1991. Coalbed methane exploration differs noticeably in several aspects from conventional oil and gas exploration. This paper is divided in three parts and discusses some geological, reservoir and drilling considerations relevant to the exploration and appraisal of a coalbed methane prospect. The first part presents geological issues such as data collection and evaluation of its associated value, building expertise to create a geological and geophysical model integrating the work of a multidisciplinary team, and assessing uncertainties of the data interpretation. A short review of the basin activity, geological and tectonic setting, and environment aspects is presented in order to illustrate some CBM exploration issues. The second part describes a comprehensive coalbed methane reservoir data acquisition program incorporating coal sample optical and chemical analyses, gas sample chromatography, canister desorption, fracture density of coal cores, and measurement of in-situ coal permeability and bounding-strata stress. Field practical concerns are then discussed such as on-site and off-site canister desorption, gas sample collection, rapid estimation of gas content, ash content, total bed moisture, and finally well testing alternatives for permeability and rock stress determination. The third part reviews drilling issues such as drilling and coring options for core hole size and casing size, rig site equipment requirements for continuous coring operations, including mud treatment equipment, core handling material and core work stations, alliance of national and foreign drilling contractors to optimize equipment and experience, and finally overview of coring procedures to identify best practices for pending operations. The paper is derived from Conoco`s experience in CBM exploration in the Lorraine Basin, North East of France.

  11. Testing probabilistic seismic hazard estimations against observations, application to France

    NASA Astrophysics Data System (ADS)

    Tasan, H. O.; Beauval, C.; Helmstetter, A.; Gueguen, P.

    2012-12-01

    Probabilistic seismic hazard calculations rely on different models and assumptions (characterization of seismic sources, recurrence laws of magnitudes, ground-motion prediction equations, …). In many countries, studies performed by different teams often led to considerably different outputs. The aim of the present study is to understand if, by using observations, it is possible to discriminate between the different hazard estimates. The work focuses on estimates obtained for the French territory (SIGMA project, seismic hazard in France). Three past studies are considered: MEDD 2002, AFPS 2006 and SIGMA 2012. Two types of observations are taken into account: the French accelerometric database (RAP), and the French macroseismic database (SisFrance). The methods were initially applied in New Zealand, Italy, and the US (Albarello and D'Amico 2008; Stirling and Gerstenberger 2010). Testing of predictions against observations is led in an extensive way, looking at different acceleration threshold levels, different return periods and different spatial windows. The GMPEs best fitting the low-acceleration dataset are first identified. In the course of the testing, we check that the main assumptions underlying the tests are fulfilled (independence of sites, no impact of aftershocks, completeness of records). The results of the testing, relying on the short accelerometric record, show that the models are overestimating the observed hazard for small accelerations (<30 cm/s2) and short return periods (< 20 years). For higher accelerations and longer return periods, models are consistent with the observed hazard. Next, tests will be led using observations on much longer time windows by using the macroseismic database.

  12. Efficacy of major anthelmintics against horse cyathostomins in France.

    PubMed

    Traversa, Donato; Castagna, Giuseppe; von Samson-Himmelstjerna, Georg; Meloni, Silvana; Bartolini, Roberto; Geurden, Thomas; Pearce, Michael C; Woringer, Emmanuel; Besognet, Bruno; Milillo, Piermarino; D'Espois, Melanie

    2012-09-10

    This paper reports a survey conducted in France during 2011 to evaluate the efficacy of commonly used anthelmintics against horse cyathostomins. A total of 40 farms and 1089 horses were screened for the presence of cyathostomins. All farms but one were positive, with an overall animal infection rate of 53.7%, ranging from 9% to 83% on individual farms. On 445 horses from 30 of these farms, a faecal egg count reduction test (FECRT) was performed to evaluate the efficacy of oral formulations of fenbendazole (FBZ), pyrantel embonate (PYR), ivermectin (IVM) and moxidectin (MOX). Calculation of the mean FECR and 95% confidence intervals (95% CI) around the mean was performed using bootstrap analysis. Resistance to FBZ was found on 17 of 18 farms investigated, with a mean reduction of 57% (95% CI: 38.5-71.2%). Suspected resistance for PYR was found on 6 of 30 farms, and confirmed on another 3 of 30 farms, with a mean reduction for PYR of 94.7% (95% CI: 88.9-98.5%). Reduced efficacy simultaneously of FBZ and PYR was found in 7 farms. Reduced efficacy of IVM was found in one animal on one farm and of MOX in one animal on another farm, and was combined with resistance against FBZ and/or PYR. These results indicate that single and multiple drug resistance and reduced efficacy in equine cyathostomins is present in France. Macrocylic lactones proved to be highly effective compounds against cyathostomins, with reduced efficacy for IVM and MOX in two farms only. These results extend present knowledge on the occurrence of drug resistant cyathostomins in Europe, and illustrate the necessity to use anthelmintics in appropriate worm control programmes.

  13. Réalisation de réseaux sur polymères par laser UV

    NASA Astrophysics Data System (ADS)

    Castex, M. C.; Fischer, A.; Simeonov, D.; Adès, D.; Siove, A.

    2003-06-01

    Nous présentons ici une méthode très simple de réalisation de réseaux d'amplitude de pas sub-micronique sur des films polymères à base de carbazote déposés sur des substrat de silice. Les réseaux sont fabriqués en irradiant avec un faisceau laser à 193nm un masque de phase placé au contact du film. La qualité des réseaux obtenus permet désormais d'envisager la réalisation de micro-cavités lasers de type planaire permettant de sélectionner une émission laser monomode autour de 400nm.

  14. A new species of Rhadinella (Serpentes: Colubridae) from the Sierra Madre del Sur of Guerrero, Mexico.

    PubMed

    Campillo, Gustavo; Dávila-Galavíz, Luis Fernando; Flores-Villela, Oscar; Campbell, Jonathan A

    2016-04-12

    We describe a new species of Rhadinella from the Sierra Madre del Sur of Guerrero, Mexico, a region where the genus was previously unknown. This diminutive species is a member of a group of snakes previously allocated in the Rhadinaea godmani group, and more recently transferred to the genus Rhadinella. These snakes may have conspicuous dark longitudinal striping on a pale brown to orange background or may have dark brown to blackish dorsal ground coloration, which mostly or completely obfuscates a pattern of longitudinal striping. The new species is mostly dark with barely discernible slightly paler or darker striping (depending on how striping is interpreted). The closest relative of the new species, on the basis of morphological similarities and biogeography, appears to be Rhadinella donaji which occurs to the east in the Sierra Madre del Sur of Oaxaca about 275 km from the type-locality of the new species.

  15. ABCC9/SUR2 in the brain: Implications for hippocampal sclerosis of aging and a potential therapeutic target.

    PubMed

    Nelson, Peter T; Jicha, Gregory A; Wang, Wang-Xia; Ighodaro, Eseosa; Artiushin, Sergey; Nichols, Colin G; Fardo, David W

    2015-11-01

    The ABCC9 gene and its polypeptide product, SUR2, are increasingly implicated in human neurologic disease, including prevalent diseases of the aged brain. SUR2 proteins are a component of the ATP-sensitive potassium ("KATP") channel, a metabolic sensor for stress and/or hypoxia that has been shown to change in aging. The KATP channel also helps regulate the neurovascular unit. Most brain cell types express SUR2, including neurons, astrocytes, oligodendrocytes, microglia, vascular smooth muscle, pericytes, and endothelial cells. Thus it is not surprising that ABCC9 gene variants are associated with risk for human brain diseases. For example, Cantu syndrome is a result of ABCC9 mutations; we discuss neurologic manifestations of this genetic syndrome. More common brain disorders linked to ABCC9 gene variants include hippocampal sclerosis of aging (HS-Aging), sleep disorders, and depression. HS-Aging is a prevalent neurological disease with pathologic features of both neurodegenerative (aberrant TDP-43) and cerebrovascular (arteriolosclerosis) disease. As to potential therapeutic intervention, the human pharmacopeia features both SUR2 agonists and antagonists, so ABCC9/SUR2 may provide a "druggable target", relevant perhaps to both HS-Aging and Alzheimer's disease. We conclude that more work is required to better understand the roles of ABCC9/SUR2 in the human brain during health and disease conditions.

  16. Multimodal 3-D reconstruction of human anatomical structures using SurLens Visualization System.

    PubMed

    Adeshina, A M; Hashim, R; Khalid, N E A; Abidin, S Z Z

    2013-03-01

    In the medical diagnosis and treatment planning, radiologists and surgeons rely heavily on the slices produced by medical imaging devices. Unfortunately, these image scanners could only present the 3-D human anatomical structure in 2-D. Traditionally, this requires medical professional concerned to study and analyze the 2-D images based on their expert experience. This is tedious, time consuming and prone to error; expecially when certain features are occluding the desired region of interest. Reconstruction procedures was earlier proposed to handle such situation. However, 3-D reconstruction system requires high performance computation and longer processing time. Integrating efficient reconstruction system into clinical procedures involves high resulting cost. Previously, brain's blood vessels reconstruction with MRA was achieved using SurLens Visualization System. However, adapting such system to other image modalities, applicable to the entire human anatomical structures, would be a meaningful contribution towards achieving a resourceful system for medical diagnosis and disease therapy. This paper attempts to adapt SurLens to possible visualisation of abnormalities in human anatomical structures using CT and MR images. The study was evaluated with brain MR images from the department of Surgery, University of North Carolina, United States and CT abdominal pelvic, from the Swedish National Infrastructure for Computing. The MR images contain around 109 datasets each of T1-FLASH, T2-Weighted, DTI and T1-MPRAGE. Significantly, visualization of human anatomical structure was achieved without prior segmentation. SurLens was adapted to visualize and display abnormalities, such as an indication of walderstrom's macroglobulinemia, stroke and penetrating brain injury in the human brain using Magentic Resonance (MR) images. Moreover, possible abnormalities in abdominal pelvic was also visualized using Computed Tomography (CT) slices. The study shows SurLens' functionality as

  17. [Polyplacophoran communities (Mollusca: Polyplacophora) at Bahia de La Paz, Baja California Sur, México].

    PubMed

    García Ríos, Cedar I; Alvarez Ruiz, Migdalia

    2007-03-01

    Eight species of polyplacophorans have been reported from La Bahia de la Paz, Baja California Sur, Mexico. We add Lepidochitona beanii, Chaetopleura lurida, Stenoplax limaciformis, S. mariposa, Lepidozona clathrata, L. serrata and Acanthochitona arragonites, increasing the known number of species to 15. Ordination analysis of five chiton communities at the site suggests a correlation of wave exposure to species composition and diversity: communities with intermediate wave exposure have more species (richness) and higher diversity (Shannon's index).

  18. [Polyplacophoran communities (Mollusca: Polyplacophora) at Bahia de La Paz, Baja California Sur, México].

    PubMed

    García Ríos, Cedar I; Alvarez Ruiz, Migdalia

    2007-03-01

    Eight species of polyplacophorans have been reported from La Bahia de la Paz, Baja California Sur, Mexico. We add Lepidochitona beanii, Chaetopleura lurida, Stenoplax limaciformis, S. mariposa, Lepidozona clathrata, L. serrata and Acanthochitona arragonites, increasing the known number of species to 15. Ordination analysis of five chiton communities at the site suggests a correlation of wave exposure to species composition and diversity: communities with intermediate wave exposure have more species (richness) and higher diversity (Shannon's index). PMID:18457125

  19. Implementing the national AIGA flash flood warning system in France

    NASA Astrophysics Data System (ADS)

    Organde, Didier; Javelle, Pierre; Demargne, Julie; Arnaud, Patrick; Caseri, Angelica; Fine, Jean-Alain; de Saint Aubin, Céline

    2015-04-01

    The French national hydro-meteorological and flood forecasting centre (SCHAPI) aims to implement a national flash flood warning system to improve flood alerts for small-to-medium (up to 1000 km2) ungauged basins. This system is based on the AIGA method, co-developed by IRSTEA these last 10 years. The method, initially set up for the Mediterranean area, is based on a simple event-based hourly hydrologic distributed model run every 15 minutes (Javelle et al. 2014). The hydrologic model ingests operational radar-gauge rainfall grids from Météo-France at a 1-km² resolution to produce discharges for successive outlets along the river network. Discharges are then compared to regionalized flood quantiles of given return periods and warnings (expressed as the range of the return period estimated in real-time) are provided on a river network map. The main interest of the method is to provide forecasters and emergency services with a synthetic view in real time of the ongoing flood situation, information that is especially critical in ungauged flood prone areas. In its enhanced national version, the hourly event-based distributed model is coupled to a continuous daily rainfall-runoff model which provides baseflow and a soil moisture index (for each 1-km² pixel) at the beginning of the hourly simulation. The rainfall-runoff models were calibrated on a selection of 700 French hydrometric stations with Météo-France radar-gauge reanalysis dataset for the 2002-2006 period. To estimate model parameters for ungauged basins, the 2 hydrologic models were regionalised by testing both regressions (using different catchment attributes, such as catchment area, soil type, and climate characteristic) and spatial proximity techniques (transposing parameters from neighbouring donor catchments), as well as different homogeneous hydrological areas. The most valuable regionalisation method was determined for each model through jack-knife cross-validation. The system performance was then

  20. Entre Reproduction et Mobilisation: les Rapports de Genre EN Formation Continue EN France et AU Canada

    NASA Astrophysics Data System (ADS)

    Fourner, Christine; Béret, Pierre; Doray, Pierre; Bélanger, Paul

    2009-01-01

    REPRODUCTION OR MOBILISATION? GENDER PROPORTIONS IN CONTINUING EDUCATION IN FRANCE AND CANADA - Initial education provisions for women have evolved greatly over the past 40 years. But what about their situation within adult education and training? This article, comparing Canada and France, shows that, while it is well known that more women than men participate in adult education, their greater presence in professional training courses is a new development. The analysis highlights certain particular findings, such as the growing demand for continuing education in Canada and the increased rate of participation by full-time employees in France. In both countries, a number of social factors continue to influence women's participation.

  1. Channel metamorphosis, floodplain disturbance, and vegetation development: Ain River, France

    NASA Astrophysics Data System (ADS)

    Marston, Richard A.; Girel, Jacky; Pautou, Guy; Piegay, Herve; Bravard, Jean-Paul; Arneson, Chris

    1995-09-01

    The purpose of this paper is to describe and explain channel metamorphosis of the Ain River in east-central France and the effects of this metamorphosis on floodplain disturbance and vegetation development. The Ain River is a 195 km long stream originating in the Jura Mountains which flows into the Rhône River between Lyon, France, and Geneva, Switzerland. The lower 40 km of the Ain River, beyond the mountain front, are situated in a valley of outwash deposits where the floodplain is 0.2 to 1.2 km wide. A complex mosaic of floodplain landscape units has developed. Maps dating back to 1766 and six sets of aerial photographs dated between 1945 and 1991 were used to document changes in channel pattern. Aerial photos and field surveys were used to compile maps of landscape units based on dominant vegetation life-forms, species, and substrate. Six maps dated between 1945 and 1991 were digitized in ARC/INFO and an overlay was generated to determine the changes in landscape units as related to channel disturbance. Change from a braided to a single-thread meandering channel probably took place in the period 1930-1950. The process of river entrenchment has occurred throughout the Holocene but has accelerated in the present century due to shortening of the river course, construction of lateral embankments, and vegetation encroachment following reservoir construction and cessation of wood-cutting and grazing. The increase in horizontal channel stability coupled with channel entrenchment have decreased floodplain disturbance and lowered the water table by approximately one meter. Pioneer and disturbance-dependent landscape units have experienced a more terrestrial-like succession to an alluvial forest. Abandoned channels have also been replaced by alluvial forests. On poorly drained soils, shrub-swamp communities of willow and hydrophytic herbaceous plants have been replaced by mixed forests of ash, alder, black poplar, and oak. On well drained alluvial soils, ash and oak

  2. Etude du stockage de l'hydrogene sur des nanostructures de carbone microporeuses

    NASA Astrophysics Data System (ADS)

    Poirier, Eric

    2007-12-01

    Le stockage de l'hydrogene par adsorption sur des adsorbants nano-structures a ete etudie sous differentes conditions de pression et de temperature. Les adsorbants etudies sont principalement des nanotubes de carbone a simple paroi ainsi que des structures metallo-organiques. Les mesures ont ete realisees a l'aide de systemes gravimetriques et volumetriques tres sensibles specialement mis au point pour de petits echantillons necessitant un degazage in situ. Les appareils developpes, au nombre de quatre, comprennent deux systemes gravimetriques et deux systemes volumetriques. Ensemble, ces systemes couvrent la plage de pressions (0-100) bars ainsi que la plage de temperatures (77-295) K. Les differentes analyses montrent que l'adsorption d'hydrogene sur les adsorbants nano-structures etudies est maximale a 77 K et varie entre environ (1.5 et 4) % masse. A temperature ambiante, l'adsorption croit lineairement avec la pression et demeure sous les 1% masse pour des pressions inferieures a 100 bars. L'adsorption d'hydrogene sur ces materiaux dans ces conditions se compare notamment a celle obtenue sur des charbons actives. La modelisation de l'adsorption a egalement ete realisee dans des conditions cryogeniques a l'aide du modele de Dubinin-Astakhov sous une forme adaptee pour l'adsorption supercritique. Les enthalpies d'adsorption calculees a partir de ce modele varient sous les 6 kJ/mole et sont donc consistantes avec des processus de physisorption. L'applicabilite du modele de Dubinin-Astakhov suggere que l'adsorption d'hydrogene puisse etre representee par un processus de remplissage des pores par un pseudo-liquide. Ces travaux s'inscrivent dans un contexte ou la capacite d'adsorption reelle des nanostructures de carbone est sujette a la controverse. En consequence, l'approche experimentale adoptee se distingue par les differentes demarches mises de l'avant pour l'obtention de mesures fiables sur des echantillons de faibles masses ainsi que par son caractere

  3. Allo France (Hello, France).

    ERIC Educational Resources Information Center

    Dominique, Philippe

    1987-01-01

    The second volume of a series of textbooks designed for young students of French is reviewed by examining how the dialogs, phonological information, grammar instruction and notes, exercises, characters and their language, cultural information, and photos and documents correspond to the authors' expressed instructional intentions. (MSE)

  4. Hospitalization of newborns and young infants for chickenpox in France.

    PubMed

    Lécuyer, Aurélie; Levy, Corinne; Gaudelus, Joel; Floret, Daniel; Soubeyrand, Benoit; Caulin, Evelyne; Cohen, Robert; Grimprel, Emmanuel

    2010-10-01

    Chickenpox is often considered more severe during the first year of life, but its course is usually mild during the first 3 months of life, presumably owing to the persistence of maternal antibodies. Hospitalization and intravenous acyclovir therapy are generally restricted to severe cases but also systematically recommended in newborns in France, irrespective of the clinical severity of the infection. This recommendation was launched in 1998 when Varicella zoster virus (VZV)-specific immunoglobulins were not available in the country and has remained unchanged since. The aim of this prospective observational study was to describe complications of varicella infection in a population of 745 children hospitalized for varicella before 1 year of age, with a specific focus on newborns. Complications occurred in 65% of cases. They were very rare before the age of 1 month (10%) but their incidence then increased progressively with age and probably the disappearance of maternal antibodies: 42% (1-2 months), 66% (3-5 months), 70% (6-8 months), and 79% (9-12 months). Conclusion Chickenpox is usually mild in newborns because most of them are protected by VZV maternal antibodies. Unless the absence of maternal VZV immunity is demonstrated, newborns with mild chickenpox should not require antiviral therapy.

  5. LIDAR developments at Clermont-Ferrand--France for atmospheric observation.

    PubMed

    Fréville, Patrick; Montoux, Nadège; Baray, Jean-Luc; Chauvigné, Aurélien; Réveret, François; Hervo, Maxime; Dionisi, Davide; Payen, Guillaume; Sellegri, Karine

    2015-01-01

    We present a Rayleigh-Mie-Raman LIDAR system in operation at Clermont-Ferrand (France) since 2008. The system provides continuous vertical tropospheric profiles of aerosols, cirrus optical properties and water vapour mixing ratio. Located in proximity to the high altitude Puy de Dôme station, labelled as the GAW global station PUY since August 2014, it is a useful tool to describe the boundary layer dynamics and hence interpret in situ measurements. This LIDAR has been upgraded with specific hardware/software developments and laboratory calibrations in order to improve the quality of the profiles, calibrate the depolarization ratio, and increase the automation of operation. As a result, we provide a climatological water vapour profile analysis for the 2009-2013 period, showing an annual cycle with a winter minimum and a summer maximum, consistent with in-situ observations at the PUY station. An overview of a preliminary climatology of cirrus clouds frequency shows that in 2014, more than 30% of days present cirrus events. Finally, the backscatter coefficient profile observed on 27 September 2014 shows the capacity of the system to detect cirrus clouds at 13 km altitude, in presence of aerosols below the 5 km altitude.

  6. Borrelia, Rickettsia, and Ehrlichia species in bat ticks, France, 2010.

    PubMed

    Socolovschi, Cristina; Kernif, Tahar; Raoult, Didier; Parola, Philippe

    2012-12-01

    Argas vespertilionis, an argasid tick associated with bats and bat habitats in Europe, Africa, and Asia has been reported to bite humans; however, studies investigating the presence of vector-borne pathogens in these ticks are lacking. Using molecular tools, we tested 5 A. vespertilionis ticks collected in 2010 from the floor of a bat-infested attic in southwestern France that had been converted into bedrooms. Rickettsia sp. AvBat, a new genotype of spotted fever group rickettsiae, was detected and cultivated from 3 of the 5 ticks. A new species of the Ehrlichia canis group, Ehrlichia sp. AvBat, was also detected in 3 ticks. Four ticks were infected with Borrelia sp. CPB1, a relapsing fever agent of the Borrelia group that caused fatal borreliosis in a bat in the United Kingdom. Further studies are needed to characterize these new agents and determine if the A. vespertilionis tick is a vector and/or reservoir of these agents. PMID:23171714

  7. The New Microbiology: a conference at the Institut de France.

    PubMed

    Radoshevich, Lilliana; Bierne, Hélène; Ribet, David; Cossart, Pascale

    2012-08-01

    In May 2012, three European Academies held a conference on the present and future of microbiology. The conference, entitled "The New Microbiology", was a joint effort of the French Académie des sciences, of the German National Academy of Sciences Leopoldina and of the British Royal Society. The organizers - Pascale Cossart and Philippe Sansonetti from the "Académie des sciences", David Holden and Richard Moxon from the "Royal Society", and Jörg Hacker and Jürgen Hesseman from the "Leopoldina Nationale Akademie der Wissenschaften" - wanted to highlight the current renaissance in the field of microbiology mostly due to the advent of technological developments and allowing for single-cell analysis, rapid and inexpensive genome-wide comparisons, sophisticated microscopy and quantitative large-scale studies of RNA regulation and proteomics. The conference took place in the historical Palais de l'Institut de France in Paris with the strong support of Jean-François Bach, Secrétaire Perpétuel of the Académie des sciences.

  8. Living Together Apart in France and the United States

    PubMed Central

    Martin, Claude; Cherlin, Andrew; Cross-Barnet, Caitlin

    2014-01-01

    Union formation involves a number of stages, as does union dissolution, and new couples often spend an initial period in a non-cohabiting intimate relationship. Yet while certain couples never share the same dwelling, “living apart together”1 has not developed widely as a long-term lifestyle option. Claude Martin in France, and Andrew Cherlin and Caitlin Cross-Barnet in the United States have studied a symmetrical phenomenon, that of couples who continue to live together while considering themselves to be separated. In this article, they draw together their analyses to describe an arrangement which, while marginal, reveals situations where residential separation is not possible, either because of the need to keep up appearances, often for the children’s sake, or because total separation is too frightening or living in separate homes is unaffordable. Beyond the differences between the two countries and the two survey fields, the authors analyse the ways in which persons who “live together apart” describe their loveless relationship that has led to explicit conjugal separation within a shared home. PMID:25170338

  9. Footedness in world soccer: an analysis of France '98.

    PubMed

    Carey, D P; Smith, G; Smith, D T; Shepherd, J W; Skriver, J; Ord, L; Rutland, A

    2001-11-01

    Most football players and coaches agree that players are capable of learning to use both feet with equal frequency and efficiency--that is, become 'two-footed'. There is also some consensus that two-footed play is associated with skill in individual players. If these assumptions are true, then the world's elite football players should be substantially less 'one-footed' than the rest of the population. To examine this issue, we quantified the pattern of foot use in a sample of 236 players from 16 teams in the 1998 World Cup (France '98). Our findings indicate that World Cup players are as right-footed as the general population (approximately 79%). The remaining players were largely left-footed and as biased towards the use of their preferred foot as their right-footed counterparts. Very few players used each foot with equal frequency. Remarkably, both left- and right-footed players were as skilled, on average, with their non-preferred foot as they were with their preferred foot, on the rare occasions when they used it. Therefore, it is unlikely that infrequent use of one foot compared to the other foot can be accounted for by skill differences between the feet. Players were most asymmetrical for set pieces; nevertheless, first touches, passes, dribbles and tackles were rarely performed with the non-preferred foot as well. Our results support a biological model of foot preference and performance, as well as demonstrating the usefulness of soccer for studies of lateral asymmetries.

  10. Restricted diversity of dental calculus methanogens over five centuries, France

    PubMed Central

    Huynh, Hong T. T.; Nkamga, Vanessa D.; Signoli, Michel; Tzortzis, Stéfan; Pinguet, Romuald; Audoly, Gilles; Aboudharam, Gérard; Drancourt, Michel

    2016-01-01

    Methanogens are acknowledged archaeal members of modern dental calculus microbiota and dental pathogen complexes. Their repertoire in ancient dental calculus is poorly known. We therefore investigated archaea in one hundred dental calculus specimens collected from individuals recovered from six archaeological sites in France dated from the 14th to 19th centuries AD. Dental calculus was demonstrated by macroscopic and cone-beam observations. In 56 calculus specimens free of PCR inhibition, PCR sequencing identified Candidatus Methanobrevibacter sp. N13 in 44.6%, Methanobrevibacter oralis in 19.6%, a new Methanomassiliicoccus luminyensis-like methanogen in 12.5%, a Candidatus Nitrososphaera evergladensis-like in one and Methanoculleus bourgensis in one specimen, respectively. One Candidatus Methanobrevibacter sp. N13 dental calculus was further documented by fluorescent in situ hybridization. The prevalence of dental calculus M. oralis was significantly lower in past populations than in modern populations (P = 0.03, Chi-square test). This investigation revealed a previously unknown repertoire of archaea found in the oral cavity of past French populations as reflected in preserved dental calculus. PMID:27166431

  11. [Certification of health-related websites in France].

    PubMed

    Nabarette, Hervé; Romaneix, François; Boyer, Célia; Darmoni, Stéphan Jacques; Rémy, Pierre-Louis; Caniard, Etienne

    2009-10-01

    The 2004 statute that created the French National Authority for Health (HAS, Haute Autorité de Santé) required it to establish a procedure for the certification of health-related web sites. The HAS established a procedure based on the HONcode certification scheme set up by the Health On the Net Foundation, with which HAS has a partnership agreement. The HONcode includes eight principles that govern the quality of online heath information and its presentation (quality of the production process). The collaboration between HAS and HON has already led to improvements in a large number of web sites in France and to their certification. The main advantages of certification for site publishers are better site quality and enhanced credibility rather than a larger audience. Quality certification has little impact on the choice of site by Internet users as they tend to use search engines to find health-related information. Future development of the procedure should work to increase the value of certification both by improving the quality of sites and in signaling quality to Internet users.

  12. Canada-France Redshift Survey - X. The quasar sample

    NASA Astrophysics Data System (ADS)

    Schade, David; Crampton, David; Hammer, F.; Le Fevre, O.; Lilly, S. J.

    1996-01-01

    Six objects with broad emission lines and redshifts from 0.48 to 2.07 were discovered among 736 extragalactic objects in the Canada-France Redshift Survey (CFRS). Although the luminosities of half of the objects are such that they are in the Seyfert regime (M_B<~-23), all would be designated as quasars in traditional surveys. Since the only selection criterion was that 17.5<=I_AB<=22.5, or approximately B<23 (assuming a continuum power-law slope alpha=-0.5), these quasars represent an unbiased, flux-limited sample. Although uncertain, the implied surface density, 200^-120-80 deg^-2, is the highest yet measured, and is in good agreement with extrapolations from other faint surveys and the evolving luminosity function models of Boyle. The distributions of the continuum properties, emission-line strengths, etc. of the quasars do not differ significantly from those of quasars selected by other means, and therefore they would have been detected in most traditional surveys. Three of the quasars may be associated with clusters or large structures of galaxies at z<~1.

  13. Wage differences according to health status in France.

    PubMed

    Ben Halima, Mohamed Ali; Rococo, Emeline

    2014-11-01

    Many OECD countries have implemented anti-discrimination laws in recent decades. However, according to the annual report published in 2010 by the French High Authority for the Fight against Discrimination and for Equality, the second most commonly cited factor in discrimination claims since 2005 is a handicap or health status. The aim of this research is to estimate the level of unexplained components in the wage gap that can be attributed to wage discrimination based on health status in France in 2010 utilizing data from the Health, Healthcare and Insurance survey among 1594 individuals. Three health indicators are used: self-perceived health status, activity limitations and long-term chronic illness. To measure the wage gap according to an individual's health status, the analysis considers the endogenous selection of health status and unobserved differences in productivity. The results demonstrate that wage discrimination is experienced by individuals in poor health regardless of the health indicator utilized. The hourly wage rate among individuals with poor self-assessed health status is on average 14.2% lower than among individuals with good self-assessed health status. However, for individuals suffering from a long-term chronic illness or an activity limitation, the gap is 6.3% and 4.5%, respectively. The decomposition performed on wage differences according to health status by correcting for health status selection bias and controlling for unobserved differences in productivity indicates that the 'unexplained component' that can be attributed to wage discrimination is equal to 50%.

  14. LIDAR Developments at Clermont-Ferrand—France for Atmospheric Observation

    PubMed Central

    Fréville, Patrick; Montoux, Nadège; Baray, Jean-Luc; Chauvigné, Aurélien; Réveret, François; Hervo, Maxime; Dionisi, Davide; Payen, Guillaume; Sellegri, Karine

    2015-01-01

    We present a Rayleigh-Mie-Raman LIDAR system in operation at Clermont-Ferrand (France) since 2008. The system provides continuous vertical tropospheric profiles of aerosols, cirrus optical properties and water vapour mixing ratio. Located in proximity to the high altitude Puy de Dôme station, labelled as the GAW global station PUY since August 2014, it is a useful tool to describe the boundary layer dynamics and hence interpret in situ measurements. This LIDAR has been upgraded with specific hardware/software developments and laboratory calibrations in order to improve the quality of the profiles, calibrate the depolarization ratio, and increase the automation of operation. As a result, we provide a climatological water vapour profile analysis for the 2009–2013 period, showing an annual cycle with a winter minimum and a summer maximum, consistent with in-situ observations at the PUY station. An overview of a preliminary climatology of cirrus clouds frequency shows that in 2014, more than 30% of days present cirrus events. Finally, the backscatter coefficient profile observed on 27 September 2014 shows the capacity of the system to detect cirrus clouds at 13 km altitude, in presence of aerosols below the 5 km altitude. PMID:25643059

  15. Trichobilharzia spp. in natural conditions in Annecy Lake, France.

    PubMed

    Jouet, Damien; Ferté, Hubert; Depaquit, Jérôme; Rudolfová, Jitka; Latour, Pierre; Zanella, Damien; Kaltenbach, Matthieu L; Léger, Nicole

    2008-06-01

    Annecy Lake is a well-known focus of human cercarial dermatitis in France. Identification of the parasites, however, was not performed in the past. Previous studies suspected two species, Trichobilharzia franki and Trichobilharzia regenti, based on the presence of parasites in mallards and/or morphological identification of snails emitting ocellate furcocercariae. Following a standardized molecular approach, we studied snails and furcocercariae and compared their haplotypes with those deposited in GenBank. The selected markers were the second internal transcribed spacer ITS-2 for the snails and ITS-2 and D2 domain of the ribosomal DNA for the parasites. Our results confirm the presence of T. franki and T. regenti and two probable new species that could be potential agents of cercarial dermatitis. All the snails emitting the ocellate furcocercariae belong to the same species identified as Radix peregra (=Radix ovata = Radix balthica). Parasite-host relationships between species of the genus Trichobilharzia and snails of the genus Radix do not seem to be as specific as supposed previously.

  16. [Faecal microbiota transplantation in France: what applicable law?].

    PubMed

    Megerlin, F; Fouassier, E

    2014-09-01

    The transplantation of gut microbiota addresses a critical gap in the treatment of recurrent severe Clostridium difficile infection, and clinical trials are ongoing throughout the world for other potential broader clinical indications. As the fecal flora inoculum has currently no legal status under European law, we consider it provisionally a sui generis biological drug rather than a human tissue transplantation, with major implications in terms of legal liability in France. The inoculum obeys a derogation to the pharmaceutical preparation rules, is processed under microbiological control, and therefore should carry a special obligation for informed consent from recipients. Failing industrializable solutions to date, this practice for the modulation of human microbiome suggests that the current legal definition of the biologic drug as well as the rules for donation and use of human-originated substances should be complemented. A new category of therapeutic products could be considered in European law, unless a rapid technological progress (the French Agency ASNM classified FMT as a drug in March 2014).

  17. The Canada-France Deep Fields Photometric Redshift Survey

    NASA Astrophysics Data System (ADS)

    Brodwin, M.; Lilly, S. J.; McCracken, H. J.; Foucaud, S.; Le Fèvre, O.; Crampton, D.

    2002-12-01

    The Canada-France Deep Fields is a UBVRIZ imaging survey covering 1 deg2 to I ~ 25. A template-fitting photometric redshift algorithm has been developed and rigorously tested, producing redshifts with a dispersion of Δ z/(1+z) ~ 0.08 for galaxies at 0

  18. Ethical and legal issue raised by DNA fingerprinting in France.

    PubMed

    Mangin, P

    1996-01-01

    As soon as DNA identification tests have been introduced as a new powerful tool in criminalistics and in paternity testing, this new technology has immediately aroused a mixture of ethical concerns, suspicion and interest among scientists and non-scientists. The major concerns about the so called 'DNA fingerprints' were related first to the possible constitution of data based by the police agencies for the purpose of identifying and investigating individuals as potential criminal suspects, and secondly to the risk of a widespread use without safeguards for private investigation as establishing paternity or the typing of a person for insurance companies. In this context, and in order to preserve civil liberties and the respect of individual privacy, the national Consultative Bioethics Committee advised, as early as 1989, the French government that DNA identification should be strictly limited to judicial use and performed by accredited laboratories. After a long debate, this recommendation has finally been adopted in July, 1994 by the French Parliament. As a result, France is presently the only member state of the European Union with such restricted legislation. This is not without raising difficulties in the implementation of the law, especially in the field of paternity testing where the demand is growing and can be satisfied in any other neighbour country. PMID:9009599

  19. [Epidemiology of diabetes in children in Languedoc-Roussillon (France)].

    PubMed

    Trellu, M; Lacombe, S; Morin, D; Dalla-Vale, F

    2015-03-01

    Since 1st January 2000, the PEDIAB-LR registry has listed new cases of diabetes in children under 16 years of age in the Languedoc-Roussillon region of France, in order to assess the incidence and epidemiological characteristics of children affected by diabetes. At the end of December 2010, 745 children had been registered. The characteristics of these children included an identical proportion of girls and boys, a mean age of 8 years at diagnosis, and a family history of type 1 diabetes in 8.4% of the cases. Inaugural ketoacidosis was observed in 69.5% of the patients and was severe in 23.7% of these cases. To replace intravenous insulin, a two-injection dosing regimen (in the morning and before dinner) was prescribed in 76.5% of cases, multi-injections of basal-bolus in 16%, and subcutaneous insulin infusion (insulin pump therapy) in 7.5% of cases. Between 2000 and 2010, there was no increase in overall incidence. It is noteworthy that age at diagnosis tended to decrease, but this was not statistically significant. In conclusion, the PEDIAB-LR registry is currently the only French registry on diabetes in children, analyzing many factors related to its incidence, such as age at diagnosis and the existence of ketoacidosis.

  20. Waning immunity against mumps in vaccinated young adults, France 2013.

    PubMed

    Vygen, Sabine; Fischer, Aurélie; Meurice, Laure; Mounchetrou Njoya, Ibrahim; Gregoris, Marina; Ndiaye, Bakhao; Ghenassia, Adrien; Poujol, Isabelle; Stahl, Jean Paul; Antona, Denise; Le Strat, Yann; Levy-Bruhl, Daniel; Rolland, Patrick

    2016-01-01

    In 2013, 15 clusters of mumps were notified in France; 72% (82/114) of the cases had been vaccinated twice with measles-mumps-rubella vaccine. To determine whether the risk of mumps increased with time since the last vaccination, we conducted a case-control study among clusters in universities and military barracks. A confirmed case had an inflammation of a salivary gland plus laboratory confirmation in 2013. A probable case presented with inflammation of a salivary gland in 2013 either lasting for > 2 days or with epidemiological link to a confirmed case. Controls had no mumps symptoms and attended the same university course, student party or military barracks. We collected clinical and vaccination data via web questionnaire and medical records. We calculated adjusted odds ratios (aOR) using logistic regression. 59% (50/85) of cases and 62% (199/321) of controls had been vaccinated twice. The odds of mumps increased for twice-vaccinated individuals by 10% for every year that had passed since the second dose (aOR 1.10; 95% confidence interval (CI): 1.02-1.19; p = 0.02). Mumps immunity waned with increasing time since vaccination. Our findings contributed to the French High Council of Public Health's decision to recommend a third MMR dose during outbreaks for individuals whose second dose dates > 10 years. PMID:26987576

  1. Early Neanderthal constructions deep in Bruniquel Cave in southwestern France.

    PubMed

    Jaubert, Jacques; Verheyden, Sophie; Genty, Dominique; Soulier, Michel; Cheng, Hai; Blamart, Dominique; Burlet, Christian; Camus, Hubert; Delaby, Serge; Deldicque, Damien; Edwards, R Lawrence; Ferrier, Catherine; Lacrampe-Cuyaubère, François; Lévêque, François; Maksud, Frédéric; Mora, Pascal; Muth, Xavier; Régnier, Édouard; Rouzaud, Jean-Noël; Santos, Frédéric

    2016-06-01

    Very little is known about Neanderthal cultures, particularly early ones. Other than lithic implements and exceptional bone tools, very few artefacts have been preserved. While those that do remain include red and black pigments and burial sites, these indications of modernity are extremely sparse and few have been precisely dated, thus greatly limiting our knowledge of these predecessors of modern humans. Here we report the dating of annular constructions made of broken stalagmites found deep in Bruniquel Cave in southwest France. The regular geometry of the stalagmite circles, the arrangement of broken stalagmites and several traces of fire demonstrate the anthropogenic origin of these constructions. Uranium-series dating of stalagmite regrowths on the structures and on burnt bone, combined with the dating of stalagmite tips in the structures, give a reliable and replicated age of 176.5 thousand years (±2.1 thousand years), making these edifices among the oldest known well-dated constructions made by humans. Their presence at 336 metres from the entrance of the cave indicates that humans from this period had already mastered the underground environment, which can be considered a major step in human modernity. PMID:27251286

  2. Occupational exposure in the fluorescent lamp recycling sector in France.

    PubMed

    Zimmermann, François; Lecler, Marie-Thérèse; Clerc, Frédéric; Chollot, Alain; Silvente, Eric; Grosjean, Jérome

    2014-07-01

    The fluorescent lamp recycling sector is growing considerably in Europe due to increasingly strict regulations aimed at inciting the consumption of low energy light bulbs and their end-of-life management. Chemical risks were assessed in fluorescent lamp recycling facilities by field measurement surveys in France, highlighting that occupational exposure and pollutant levels in the working environment were correlated with the main recycling steps and processes. The mean levels of worker exposure are 4.4 mg/m(3), 15.4 μg/m(3), 14.0 μg/m(3), 247.6 μg/m(3), respectively, for total inhalable dust, mercury, lead and yttrium. The mean levels of airborne pollutants are 3.1mg/m(3), 9.0 μg/m(3), 9.0 μg/m(3), 219.2 μg/m(3), respectively, for total inhalable dust, mercury, lead and yttrium. The ranges are very wide. Surface samples from employees' skin and granulometric analysis were also carried out. The overview shows that all the stages and processes involved in lamp recycling are concerned by the risk of hazardous substances penetrating into the bodies of employees, although exposure of the latter varies depending on the processes and tasks they perform. The conclusion of this study strongly recommends the development of a new generation of processes in parallel with more information sharing and regulatory measures.

  3. [The health and welfare system for elderly in France].

    PubMed

    Sauvaget, C; Ogawa, K; Tsuji, I; Hisamichi, S

    1998-07-01

    Dichotomy is the main characteristic of the Health and Welfare system in France. This system lies on two distinct fields, the medical field which is managed by the National Government, and the social field managed by the Local Government. The French home care policy for the elderly has developed a large number of services to assist in activities of daily living, to provide nursing and medical care at home, to improve living conditions, to maintain social relationships, and to postpone institutionalization and hospitalization, respectively. The main home care service is represented by "home helpers" who provide maid Notiniralics services. The second widely used service is the "home care service" performed by a team of nurses, assistant-nurses, psychologists, physiotherapists. This team provides nursing care and assistance in activities of daily living. As for institutions for the elderly, they are divided into welfare and medical institutions. The welfare institutions include social establishments like shelter homes and nursing homes. The medical institutions are mostly represented by long-term care hospitals. One of the main goals of the aging policy is to create medical wards in welfare institutions in response to the increased dependency of the institutionalized elderly. Recent experimental and innovative concepts have been established, such as "shelter homes for dependent elderly" for physically or cognitively impaired elderly.

  4. [Creation and organization of an antivenomous serum bank in France].

    PubMed

    Darsonval, Astrid; Boels, David; Clerc, Marie-Anne; De Haro, Luc; Penot-Ragon, Christine; Moal, Fréderic; Quistinic, Pierre; Lourdais, Olivier; Harry, Patrick

    2010-09-01

    For several years exotic snakes have been bred in France. In view of the increased risk of envenomation from some of these species, the Poison Centre in Angers has joined forces with several private licensed snake breeders to create an Anti-venom Serum Bank. The main objective of the new organization is to provide an effective means of dealing with bites and subsequent envenomation by exotic snakes by managing a stock of anti-venom serums in a hospital pharmacy, so that cases can be treated as quickly as possible. The hospital pharmacy has the authority to purchase and supply the anti-venom serums. The selection and purchase of the serums is done in conjunction with the French Ministry of Ecology, the French Drug Agency and specialist doctors. At the time of writing, the Antivenom Serum Bank has the capacity to treat about thirty different kinds of envenomation, compared to the 135 exotic venomous snake species officially registered. In the long term the Anti-venom Serum Bank will help eradicate the use of serums from unauthorized sources, evaluate the safety and efficacy of new serums and reduce transport times.

  5. How to become a graduate biomedical engineer in France.

    PubMed

    Rieu, Regis; Plilion, Barbara

    2007-01-01

    In France, to be an engineer first means to exert a profession that requires a good level of technical expertise, directly or indirectly bound to producing goods or services for the community. An engineer designs new products, has a manufacturing responsibility or is a project manager. He may discuss technologies and methods being used or argue about them if need be. That's how he differs from a lower level technician who only implements in conformance with guidelines. To be an engineer has a second meaning: earning the engineering degree after rather long training period (usually 5 years of studies, an equivalent of a Master degree), with a curriculum that includes a balance of scientific, technical and even economic studies. We stress these two definitions since they sometimes don't overlap within companies: --It is possible to get an engineering job without having an engineering degree. --The career of graduate engineers often leads them to managerial positions where technical aspects may disappear or, at least, be reduced.

  6. Franc D. Ingraham and the genesis of pediatric neurosurgery.

    PubMed

    Lohani, Subash; Cohen, Alan R

    2013-06-01

    In 1929, Franc D. Ingraham, Harvey Cushing's protégé, established the first pediatric neurosurgical unit in the world at Boston Children's Hospital and dedicated his career to the neurosurgical care of children. He trained with both Cushing and Dandy and spent 1 year working in Oxford with Sherrington, who considered Ingraham to be the finest operative surgeon ever to work in his laboratory. Ingraham was instrumental in developing novel treatments, which he compiled in his classic book, Neurosurgery of Infancy and Childhood. Although he was modest and shy, Ingraham loved to entertain children with magic and enjoyed photography in and out of the operating room. Unfortunately, his career was plagued by personal illness, and he died young in 1965 at the age of 67. Despite his prolific 36-year neurosurgical career, Ingraham remained an associate professor at Harvard at his retirement. To recognize his remarkable contributions, Harvard established an endowed chair in his name in 1967. Ingraham was a pioneer and a leader in the development of pediatric neurosurgery by virtue of his imagination, intelligence, and ability to lead and inspire others. Cushing has come to be regarded as the founder of neurosurgery. It is fair to conclude that Ingraham, his disciple, is the founder of pediatric neurosurgery. PMID:23601016

  7. The 22nd Ion Channel Meeting, September 2011, France

    PubMed Central

    Goaillard, Jean-Marc; Groc, Laurent; Lévi, Sabine; Mantegazza, Massimo; Matifat, Fabrice; Morel, Jean-Luc; Baron-Forster, Anne

    2012-01-01

    The 22nd Ion Channel Meeting was organized by the French Ion Channel Society (Association Canaux Ioniques) from the 25th to the 28th of September 2011 on the French Riviera (Giens). This year again, more than one hundred researchers from France, Europe and extra-European countries gathered to present and discuss their recent advances and future challenges in the ion channels and transporters field. The scientific committee organized a plenary lecture and five thematic symposia by inviting international researchers to present their recent outstanding work on themes as diverse as muscular channelopathies, regulation of channels by extracellular matrix, receptor-channels interactions, localization and distribution of ion channels, their involvement in the cell life and death, and finally how they participate in the evolution and adaptability of cellular excitability. These presentations are summarized in this meeting report. Two sessions of oral communications selected from submitted abstracts and two poster sessions were also organized to present the ongoing work of young researchers worldwide. PMID:22647366

  8. Borrelia, Rickettsia, and Ehrlichia Species in Bat Ticks, France, 2010

    PubMed Central

    Socolovschi, Cristina; Kernif, Tahar; Raoult, Didier

    2012-01-01

    Argas vespertilionis, an argasid tick associated with bats and bat habitats in Europe, Africa, and Asia has been reported to bite humans; however, studies investigating the presence of vector-borne pathogens in these ticks are lacking. Using molecular tools, we tested 5 A. vespertilionis ticks collected in 2010 from the floor of a bat-infested attic in southwestern France that had been converted into bedrooms. Rickettsia sp. AvBat, a new genotype of spotted fever group rickettsiae, was detected and cultivated from 3 of the 5 ticks. A new species of the Ehrlichia canis group, Ehrlichia sp. AvBat, was also detected in 3 ticks. Four ticks were infected with Borrelia sp. CPB1, a relapsing fever agent of the Borrelia group that caused fatal borreliosis in a bat in the United Kingdom. Further studies are needed to characterize these new agents and determine if the A. vespertilionis tick is a vector and/or reservoir of these agents. PMID:23171714

  9. Priority organic pollutants in the urban water cycle (Toulouse, France).

    PubMed

    Sablayrolles, C; Breton, A; Vialle, C; Vignoles, C; Montréjaud-Vignoles, M

    2011-01-01

    Application of the European Water Framework Directive requires Member States to have better understanding of the quality of surface waters in order to improve knowledge of priority pollutants. Xenobiotics in urban receiving waters are an emerging concern. This study proposes a screening campaign of nine molecular species of xenobiotics in a separated sewer system. Five sites were investigated over one year in Toulouse (France) using quantitative monitoring. For each sample, polycyclic aromatic hydrocarbons, polychlorinated biphenyls, nonylphenols, diethelhexylphthalate, linear alkylbenzene sulphonates, methyl tert-butylether, total hydrocarbons, estradiol and ethinylestradiol were analysed. Ground, rain and roof collected water concentrations are similar to treated wastewater levels. Run-off water was the most polluted of the five types investigated, discharged into the aquatic environment. The wastewater treatment plant reduced xenobiotic concentrations by 66% before discharge into the environment. Regarding environmental quality standards, observed concentrations in waters were in compliance with standards. The results show that xenobiotic concentrations are variable over time and space in all urban water compartments.

  10. Motor sport in France: testing-ground for the world.

    PubMed

    Cofaigh, Eamon O

    2011-01-01

    The birth of the automobile in the late nineteenth century was greeted with a mixture of awe, scepticism and sometimes even disdain from sections of the European public. In this article, the steps taken in France to pioneer and promote this new invention are examined. Unreliable and noisy, the early automobile owes a debt of gratitude to the French aristocracy who organised and codified motor racing in an effort to test these new inventions while at the same time introduce them to a wider public. City-to-city races demonstrated the potential of the automobile before the initiative of Gordon Bennett proved to be the catalyst for the birth of international motor sport as we recognise it today. Finally this article looks at the special connection between Le Mans and the automobile. Le Mans has, through its 24-hour race, maintained a strong link with the development of everyday automobile tourism and offers the enthusiast an alternative to the machines that reach incredible speeds on modern-day closed circuits. This article examines how French roads were veritable testing grounds for the earliest cars and how the public roads of Le Mans maintain the tradition to this day.

  11. Restricted diversity of dental calculus methanogens over five centuries, France.

    PubMed

    Huynh, Hong T T; Nkamga, Vanessa D; Signoli, Michel; Tzortzis, Stéfan; Pinguet, Romuald; Audoly, Gilles; Aboudharam, Gérard; Drancourt, Michel

    2016-01-01

    Methanogens are acknowledged archaeal members of modern dental calculus microbiota and dental pathogen complexes. Their repertoire in ancient dental calculus is poorly known. We therefore investigated archaea in one hundred dental calculus specimens collected from individuals recovered from six archaeological sites in France dated from the 14(th) to 19(th) centuries AD. Dental calculus was demonstrated by macroscopic and cone-beam observations. In 56 calculus specimens free of PCR inhibition, PCR sequencing identified Candidatus Methanobrevibacter sp. N13 in 44.6%, Methanobrevibacter oralis in 19.6%, a new Methanomassiliicoccus luminyensis-like methanogen in 12.5%, a Candidatus Nitrososphaera evergladensis-like in one and Methanoculleus bourgensis in one specimen, respectively. One Candidatus Methanobrevibacter sp. N13 dental calculus was further documented by fluorescent in situ hybridization. The prevalence of dental calculus M. oralis was significantly lower in past populations than in modern populations (P = 0.03, Chi-square test). This investigation revealed a previously unknown repertoire of archaea found in the oral cavity of past French populations as reflected in preserved dental calculus. PMID:27166431

  12. Holocene Environmental Signals from Mollusk Assemblages in Burgundy (France)

    NASA Astrophysics Data System (ADS)

    Rousseau, Denis-Didier; Limondin, Nicole; Puissegur, Jean-Jacques

    1993-09-01

    The malacofaunas of Burgundy, France, reflect changes in climate and the activities of man during the Holocene. Statistical analyses based on the Shannon diversity index and correspondence analysis are used to describe the mollusk assemblages in a composite sequence based on three well-dated sites. The variation demonstrated by the mollusks suggests that a two-step warming took place between 10,000 and 9000 and 8000 and 6000 yr B.P. in relative agreement with the timing of the deglaciation in the tropical Atlantic Ocean proposed by Mix and Ruddiman (1985, Quaternary Science Reviews 4, 59-108). High humidity, partly associated with widespread inundations of the valleys between 10,000 and 8000 yr B.P., may be related to estimated variations in the rate of freshwater discharge to the Atlantic Ocean reported by Fairbanks (1989, Nature 342, 637-642). The increasing impact of human activities on the environment during the past 2000 yr is indicated by the low diversity of the mollusk assemblages, demonstrating the need for careful interpretation of the youngest Holocene sediments in this region.

  13. ["Veille sanitaire": tools, functions, process of healthcare monitoring in France].

    PubMed

    Eilstein, D; Salines, G; Desenclos, J-C

    2012-10-01

    In France, the term "veille sanitaire" is widely used to designate healthcare monitoring. It contains, however, a set of concepts that are not shared equally by the entire scientific community. The same is true for activities that are part of it, even if some (surveillance for example) are already well defined. Concepts such as "observation", "vigilance", "alert" for example are not always clear. Furthermore, the use of these words in everyday language maintains this ambiguity. Thus, it seemed necessary to recall these definitions as already used in the literature or legislation texts and to make alternative suggestions. This formalization cannot be carried out without thinking about the structure of "veille sanitaire" and its components. Proposals are provided bringing out concepts of formated "veille" (monitoring) and non-formatted "veille" (monitoring). Definitions, functions, (methods and tools, processes) of these two components are outlined here as well as the cooperative relationship they sustain. The authors have attempted to provide the scientific community with a reference framework useful for exchanging information to promote research and methodological development dedicated to this public health application of epidemiology.

  14. The 23rd Annual Meeting of the European Tissue Repair Society (ETRS) in Reims, France

    PubMed Central

    2014-01-01

    The 23rd Annual Meeting of the European Tissue Repair Society, Reims, France, October 23 to 25, 2013 focused on tissue repair and regenerative medicine covering topics such as stem cells, biomaterials, tissue engineering, and burns. PMID:24552134

  15. "Onions and Stripey Tee-Shirts" or how Do Primary Pupils Learn about France?

    ERIC Educational Resources Information Center

    Esarte-Sarries, Veronica

    1989-01-01

    Describes how sources such as television, visits, and personal accounts influence British students' impressions and stereotypes of France and French culture. Teachers can help students to interpret these impressions beyond perception from a typical British norm. (CB)

  16. Latest Developments in Early Bilingual Education in France and Southern Europe.

    ERIC Educational Resources Information Center

    Gerth, Klaus-Erich

    1988-01-01

    Analyzes changes that have occurred in language and culture teaching in Spain, Italy, and France in each country's specific context and discusses the scientific and pedagogical implications of each country's early bilingual education developments. (Author/CB)

  17. Fish community comparisons along environmental gradients in lakes of France and north-east USA

    EPA Science Inventory

    To assess whether eight traits of fish communities (species richness, three reproductive traits and four trophic traits) respond similarly to environmental gradients, and consequently display convergence between the lakes of France and north-east USA (NEUSA). Location 75 Frenc...

  18. [Hospital-based health technology assessment in France: how to proceed to evaluate innovative medical devices?].

    PubMed

    Martelli, N; van den Brink, H; Denies, F; Dervaux, B; Germe, A F; Prognon, P; Pineau, J

    2014-01-01

    Innovative medical devices offer solutions to medical problems and greatly improve patients' outcomes. Like National Health Technology Assessment (HTA) agencies, hospitals face numerous requests for innovative and costly medical devices. To help local decision-makers, different approaches of hospital-based HTA (HB-HTA) have been adopted worldwide. The objective of the present paper is to explore HB-HTA models for adopting innovative medical devices in France and elsewhere. Four different models have been conceptualized: "ambassador" model, "mini-HTA" model, "HTA unit" model and "internal committee". Apparently, "HTA unit" and "internal committee" (or a mixture of both models) are the prevailing HB-HTA models in France. Nevertheless, some weaknesses of these models have been pointed out in previous works. Only few examples involving hospital pharmacists have been found abroad, except in France and in Italy. Finally, the harmonization of the assessment of innovative medical devices in France needs a better understanding of HB-HTA practices.

  19. Science Education at the National Institute for Pedagogical Research, Paris, France.

    ERIC Educational Resources Information Center

    Host, Victor

    1979-01-01

    Discusses three major areas of research in science education which take place at the National Institute for Pedagogical Research (INRP), Paris, France. European cooperation, future prospects and a list of publications of the INRP are also presented. (HM)

  20. Prevalence survey and first molecular characterization of Echinococcus granulosus in France.

    PubMed

    Umhang, G; Richomme, C; Boucher, J-M; Hormaz, V; Boué, F

    2013-04-01

    Human cystic echinococcosis (hydatid disease) caused by the Echinococcus granulosus tapeworm continues to be a substantial cause of morbidity and mortality in many parts of the world. France is still considered as endemic area, but the current infestation by E. granulosus of intermediate hosts in France remains currently unknown due to the absence of official data reporting for the last 20 years. A 1-year prevalence survey was conducted in the 24 slaughterhouses of ten departments of the South of France. We demonstrate that the E. granulosus parasite is still currently present at low prevalence at slaughterhouses in the study area (4 cases for 100,000 sheep and 3 cases for 100,000 cattle). In addition, we assess the presence of genotype G1 in infected animals and identify for the first time in France genotypes G2 and G3 of E. granulosus sensu stricto.

  1. Tropical Storm Frances and Hurricane Ivan Situation Report, September 9, 2004 (10:00 PM EDT)

    SciTech Connect

    2004-09-09

    The report provides highlights related to impacts of Hurricane Frances and Hurricane Ivan in the Florida area. Sections on electric information, oil and gas information, and county outage data are provided.

  2. Tropical Storm Frances/ Hurricane Ivan Situation Report, September 10, 2014 (10:00 AM EDT)

    SciTech Connect

    2004-09-10

    The report provides highlights related to impacts of Hurricane Frances and Hurricane Ivan in the Florida area. Sections on electric information, oil and gas information, county outage data, and a table for restoration targets/status are provided.

  3. Tropical Storm Frances Situation Report, September 7, 2004 (10:00 PM EDT)

    SciTech Connect

    2004-09-07

    The report provides highlights related to impacts of Tropical Storm Frances in the Florida area. Sections on electric information, oil and gas information, storm track, and county outage data are provided.

  4. Bronchiolitis obliterans organizing pneumonia syndrome primed by radiation therapy to the breast. The Groupe d'Etudes et de Recherche sur les Maladies Orphelines Pulmonaires (GERM"O"P)

    PubMed

    Crestani, B; Valeyre, D; Roden, S; Wallaert, B; Dalphin, J C; Cordier, J F

    1998-12-01

    Reports of bronchiolitis obliterans organizing pneumonia (BOOP) occurring in women after radiation therapy for breast cancer have suggested that radiation to the lung could participate in the development of BOOP. We now describe the clinical, radiographic, functional, and bronchoalveolar lavage characteristics of this syndrome in a series of 15 patients reported to the Groupe d'Etudes et de Recherche sur les Maladies "Orphelines" Pulmonaires (GERM"O"P) in France. All 15 women (60 +/- 6 yr of age) fulfilled the following inclusion criteria: (1) radiation therapy to the breast within 12 mo, (2) general and/or respiratory symptoms lasting for at least 2 wk, (3) lung infiltrates outside the radiation port, and (4) no specific cause. The patients presented with fever, nonproductive cough, mild dyspnea, and peripheral alveolar opacities on chest radiograph with a characteristic migratory pattern. In five patients, BOOP was found at lung pathologic analysis. In all the patients dramatic improvement was obtained with corticosteroids, but relapses occurred in 12 patients while tapering or after stopping corticosteroids. This report demonstrates that a characteristic BOOP syndrome may occur after radiation therapy to the breast, including tangential radiation to the lung, thus suggesting that radiation therapy may prime the development of BOOP.

  5. Hospital based ethics, current situation in France: between "Espaces" and committees.

    PubMed

    Guerrier, M

    2006-09-01

    Unlike research ethics committees, which were created in 1988, the number of functioning hospital based ethical organisations in France, such as clinical ethics committees, is unknown. The objectives of such structures are diverse. A recent law created regional ethical forums, the objectives of which are education, debate, and research in relation to healthcare ethics. This paper discusses the current situation in France and the possible evolution and conflicts induced by this law. The creation of official healthcare ethics structures raises several issues.

  6. A cluster of three cases of botulism due to Clostridium baratii type F, France, August 2015.

    PubMed

    Tréhard, Hélène; Poujol, Isabelle; Mazuet, Christelle; Blanc, Quentin; Gillet, Yves; Rossignol, Frédérique; Popoff, Michel-Robert; Jourdan Da Silva, Nathalie

    2016-01-01

    A cluster of three cases of food-borne botulism due to Clostridium baratii type F occurred in France in August 2015. All cases required respiratory assistance. Consumption of a Bolognese sauce at the same restaurant was the likely source of contamination. Clostridium baratii was isolated both from stool specimens from the three patients and ground meat used to prepare the sauce. This is the second episode reported in France caused by this rare pathogen.

  7. New introductions of enterovirus 71 subgenogroup C4 strains, France, 2012.

    PubMed

    Schuffenecker, Isabelle; Henquell, Cécile; Mirand, Audrey; Coste-Burel, Marianne; Marque-Juillet, Stéphanie; Desbois, Delphine; Lagathu, Gisèle; Bornebusch, Laure; Bailly, Jean-Luc; Lina, Bruno

    2014-08-01

    In France during 2012, human enterovirus 71 (EV-A71) subgenogroup C4 strains were detected in 4 children hospitalized for neonatal fever or meningitis. Phylogenetic analysis showed novel and independent EV-A71 introductions, presumably from China, and suggested circulation of C4 strains throughout France. This observation emphasizes the need for monitoring EV-A71 infections in Europe. PMID:25061698

  8. Two new species of Bryobia (Acarina, Prostigmata, Tetranychidae) from South France

    PubMed Central

    Auger, Philippe; Arabuli, Tea; Migeon, Alain

    2015-01-01

    Abstract Two new species of Tetranychidae belonging to the genus Bryobia are reported from France. Bryobia belliloci sp. n. and Bryobia gigas sp. n. collected on Genista cinerea and Bituminaria bituminosa, respectively, are described and illustrated in the present work. Additional data to the original description of Bryobia cinereae are given and an identification key to known Bryobia species from France is also provided. PMID:25685021

  9. Outbreak of tularaemia in brown hares (Lepus europaeus) in France, January to March 2011.

    PubMed

    Decors, A; Lesage, C; Jourdain, E; Giraud, P; Houbron, P; Vanhem, P; Madani, N; Madani, M

    2011-07-14

    We report an outbreak of tularaemia in brown hares (Lepus europaeus) in France, which occurred from January to March 2011 and was characterised by a high mortality rate in the local hare population. In France, hare tularaemia is usually sporadic and does not significantly affect hare populations. The epizootic form of the outbreak reported here led us to reconsider the potential associated risks for hare populations and public health.

  10. A cluster of three cases of botulism due to Clostridium baratii type F, France, August 2015.

    PubMed

    Tréhard, Hélène; Poujol, Isabelle; Mazuet, Christelle; Blanc, Quentin; Gillet, Yves; Rossignol, Frédérique; Popoff, Michel-Robert; Jourdan Da Silva, Nathalie

    2016-01-01

    A cluster of three cases of food-borne botulism due to Clostridium baratii type F occurred in France in August 2015. All cases required respiratory assistance. Consumption of a Bolognese sauce at the same restaurant was the likely source of contamination. Clostridium baratii was isolated both from stool specimens from the three patients and ground meat used to prepare the sauce. This is the second episode reported in France caused by this rare pathogen. PMID:26848055

  11. [From FRANCE 2 to FRANCE TAVI: are indications, technique and results of transcatheter aortic valve replacement the same?].

    PubMed

    Auffret, Vincent; Bedossa, Marc; Boulmier, Dominique; Verhoye, Jean Philippe; Ruggieri, Vito Giovanni; Koning, René; Laskar, Marc; Van Belle, Éric; Leprince, Pascal; Collet, Jean Philippe; Iung, Bernard; Lefèvre, Thierry; Eltchaninoff, Helene; Gilard, Martine; Le Breton, Hervé

    2015-01-01

    Transcatheter aortic valve implantation (TAVI) is indicated in patients with severe symptomatic aortic stenosis who are not suitable for surgery or should be considered when there is a high surgical risk as assessed by a heart team. There is a decrease in mean logistic EuroSCORE since January 2010, which translates a gradual evolution in patients' selection. Expertise of geriatricians to further assess frailty is a key step in the risk stratification process of this elderly population (mean age: 83.4±7.3 years). Femoral access is used in 80% of cases with a procedural success rate higher than 95%. In-hospital mortality rate is 5.9%. The main complications of the procedure are aortic annulus rupture (0.9% in FRANCE TAVI), tamponade (2.3%), stroke (2.2%), severe paravalvular leak (1.3%) and permanent pacemaker implantation (15%). The awaited results of PARTNER II and SURTAVI may lead to expand the indications to lower-risk patients if it is shown that TAVI is non-inferior to surgery in this population which has been suggested by the recent randomized NOTION Trial while the CoreValve Pivotal Trial even points in the direction of a possible superiority of the percutaneous technique over surgery. PMID:26208911

  12. Epidemiology of atrial fibrillation in France: extrapolation of international epidemiological data to France and analysis of French hospitalization data.

    PubMed

    Charlemagne, Agnès; Blacher, Jacques; Cohen, Ariel; Collet, Jean-Philippe; Diévart, François; de Groote, Pascal; Hanon, Olivier; Leenhardt, Antoine; Pinel, Jean-François; Pisica-Donose, George; Le Heuzey, Jean-Yves

    2011-02-01

    The prevalence of atrial fibrillation is steadily increasing throughout the world because of ageing populations and better management of coronary heart disease. An international literature review was conducted to estimate the prevalence and incidence of atrial fibrillation in France. A review of the literature on comorbidities was also performed. Finally, French mortality and hospitalization data were analysed using the PMSI database. The prevalence of atrial fibrillation is estimated to be between 600,000 and 1 million people; of these, two-thirds are aged >75 years. The incidence is estimated at between 110,000 and 230,000 new cases per year. In 2008, 412,000 hospitalized patients had a diagnosis of atrial fibrillation; this figure increased by 26% in the 3-year period between 2005 and 2008. These findings highlight the importance of targeting therapy, of upstream therapy, and of therapy that provides clear clinical and economic advantages over the well-established reductions already achieved in atrial fibrillation morbidity, mortality and cost. In addition, new prevention strategies should be developed, particularly secondary prevention strategies in patients with cardiovascular diseases. PMID:21402346

  13. Identifying driving climate factors of wheat and maize yields inter-annual variability in France

    NASA Astrophysics Data System (ADS)

    Ceglar, Andrej; Toreti, Andrea; Lecerf, Remi; Dentener, Frank J.

    2015-04-01

    A canonical powered Partial Least Squares Regression (PLSR) approach is here used to estimate the relationship between meteorological variables and crop (durum wheat and grain maize) yield time series over France. This method combines the advantages of both the Canonical Correlation Analysis (CCA) and the PLSR. The latter is mainly based on the extraction of a subset of latent variables (having the best predictive power) from the full set of predictors. The method is applied to detrended (by using a LOESS approach) time series of crop yields and monthly mean temperature, cumulated precipitation and global solar radiation during the growing seasons from 1990 to 2011. Results show that, overall, temperature has a substantial influence on winter wheat yields in south-western and eastern France, while rainfall plays an important role in the northern and southern parts of the country. Finally, radiation is more important over the southern part of France. Concerning grain maize, the inferred statistical models show relatively low skill over the northern part of France, where inter-annual yield variability is low. Overall, results show that temperature is the most important variable influencing grain maize yields over the southern and eastern parts of France, while rainfall is more important in the central and northern parts of the country. Finally, global radiation is the main meteorological factor over the westernmost part of France.

  14. Molecular evidence for Bartonella spp. in cat and dog fleas from Germany and France.

    PubMed

    Just, F T; Gilles, J; Pradel, I; Pfalzer, S; Lengauer, H; Hellmann, K; Pfister, K

    2008-10-01

    Nine hundred and fifty-two fleas were collected from 148 cats and 133 dogs at 18 widely distributed geographic locations in Germany and France and examined for the presence of six different Bartonella spp. (Bartonella bacilliformis, Bartonella clarridgeiae, Bartonella elizabethae, Bartonella henselae, Bartonella quintana, Bartonella vinsonii subsp. berkhoffii) by PCR. Thirty-five specimens (3.7%) tested positive for either B. henselae (14 positive fleas) or B. clarridgeiae (21 positive fleas). DNA of other Bartonella spp. were not detected. Bartonella clarridgeiae was the dominating species in samples from France (19 out of 22 positive fleas), whereas B. henselae was more frequent in Germany (11 out of 13 positive fleas). With 3.5% (22 out of 632 fleas) in France and 4.1% (13 out of 320 fleas) in Germany, the overall prevalences of pathogen did not vary significantly between the flea populations of both countries. 5.4% of cats in France versus 16.1% of cats from Germany were infested by fleas carrying Bartonella, whereas 9.5% of dogs in France but none of the examined dogs from Germany were infested by Bartonella positive fleas. The molecular evidence of Bartonella infections reveals that agents of zoonotic potential are established in flea populations in Germany and France and that the spectrum of species can vary significantly from country to country.

  15. Mechanisms of anticonvulsant and sedative actions of the ethanolic stem-bark extract of Ficus sur Forssk (Moraceae) in rodents.

    PubMed

    Ishola, Ismail O; Olayemi, Sunday O; Yemitan, Omoniyi K; Ekpemandudiri, Ngozi K

    2013-11-01

    Ficus sur Forssk (Moraceae) is used in traditional African medicine in the treatment of epilepsy, pain and inflammations. Anticonvulsant activity was investigated using picrotoxin (PTX), strychnine (SCN), isoniazid (INZ), pentylenetetrazole (PTZ) and N-methyl-D-aspartic acid NMDA models of convulsion. The phytochemical analysis of the extract revealed the presence of flavonoids, saponins, tannins, alkaloids and anthraquinone. Oral administration of Ficus sur, 1 h before intraperitoneal injection of chemical convulsants significantly (p < 0.05) delayed the onset and prolonged the duration of convulsions in PTX, SCN, INZ, PTZ and NMDA-induced seizures. However, the anticonvulsant activity of the ethanolic extract of Ficus sur was significantly reversed following intraperitoneal pre-treatment with flumazenil (GABA receptor antagonist), cyproheptadine (5-HT2 receptor antagonist) and L-NNA (nitric oxide synthase inhibitor) in picrotoxin-induced convulsion. The data obtained suggest that ethanol extract of Ficus sur possessed significant anticonvulsant effect, thereby confirming the traditional uses of Ficus sur in the treatment of epilepsies; mechanisms of which could involve interaction with GABAergic, glycinergic, serotonergic and glutaminergic system barks.

  16. Phenylephrine preconditioning in embryonic heart H9c2 cells is mediated by up-regulation of SUR2B/Kir6.2: A first evidence for functional role of SUR2B in sarcolemmal KATP channels and cardioprotection.

    PubMed

    Jovanović, Sofija; Ballantyne, Thomas; Du, Qingyou; Blagojević, Miloš; Jovanović, Aleksandar

    2016-01-01

    ATP-sensitive K(+) (KATP) channels were originally described in cardiomyocytes, where physiological levels of intracellular ATP keep them in a closed state. Structurally, these channels are composed of pore-forming inward rectifier, Kir6.1 or Kir6.2, and a regulatory, ATP-binding subunit, SUR1, SUR2A or SUR2B. SUR1 and Kir6.2 form pancreatic type of KATP channels, SUR2A and Kir6.2 form cardiac type of KATP channels, SUR2B and Kir6.1 form vascular smooth muscle type of KATP channels. The presence of SUR2B has been described in cardiomyocytes, but its functional significance and role has remained unknown. Pretreatment with phenylephrine (100nM) for 24h increased mRNA levels of SUR2B and Kir6.2, without affecting those levels of SUR1, SUR2A and Kir6.1 in embryonic heart H9c2 cells. Such increase was associated with increased K(+) current through KATP channels and Kir6.2/SUR2B protein complexes as revealed by whole cell patch clamp electrophysiology and immunoprecipitation/Western blotting respectively. Pretreatment with phenylephrine (100nM) generated a cellular phenotype that acquired resistance to chemical hypoxia induced by 2,4-dinitrophenol (DNP; 10mM), which was accompanied by increased in K(+) current in response to DNP (10mM). Cytoprotection afforded by phenylephrine (100nM) was abolished by infection of H9c2 cells with adenovirus containing Kir6.2AFA, a mutant form of Kir6.2 with largely reduced K(+) conductance. Taking all together, the present findings demonstrate that the activation of α1-adrenoceptors up-regulates SUR2B/Kir6.2 to confer cardioprotection. This is the first account of possible physiological role of SUR2B in cardiomyocytes.

  17. The RHYTMME system: an operational real-time warning and mapping system for flash floods, debris flows, landslide and rock falls in Southeastern France.

    NASA Astrophysics Data System (ADS)

    Fouchier, Catherine; Mériaux, Patrice; Atger, Frédéric; Ecrepont, Stéphane; Liébault, Frédéric; Bertrand, Mélanie; Bel, Coraline; Batista, Dominique; Azemard, Pierre; Saint-Martin, Clotilde; Javelle, Pierre

    2016-04-01

    Almost all municipalities of Southeastern France are concerned by natural hazards triggered by heavy rainfalls such as floods, debris flows, landslides and rock falls. Although some tools exist to forecast and monitor heavy rains and floods in France, their spatial resolution sometimes does not meet the needs of local risk managers who have to monitor events at a small spatial scale. In order to improve the risk management in the mountainous and Mediterranean areas of Southeastern France, Irstea and Météo-France have led the RHYTMME project. The goal of this project is to improve the ability to forecast and localize high-risk rainfall-induced hazards in the Provence-Alpes-Côte d'Azur administrative area. This goal is currently under achievement thanks to the implementation of a real-time warning and mapping system for rainfall induced natural hazards, fed by radar data and whose outputs are made available via the Internet to operators in charge of risk management (local and regional authorities, emergency and rescue services, road and rail networks managers, ...). This system provides maps which display in real-time: - the radar estimations of rainfall for different rain durations and at the spatial resolution of 1 km² (Westrelin et al., 2013), - the estimation of the scarcity of these rainfall estimations, also at the spatial resolution of 1 km², thanks to a comparison with threshold values provided by a regionalized stochastic hourly point rainfall generator (Arnaud et al., 2007), - an anticipation of the rivers discharges, computed at the outlet of 1700 watersheds of Southeastern France thanks to the AIGA warning system which combines a rainfall runoff model and an estimation of the scarcity of the discharges thanks to a comparison with threshold values (Javelle et al., 2014). Maps of susceptibility to debris flow, landslide and rock falls can also be displayed in the RHYTMME warning system along with the real time maps of rainfall hazard (Batista, 2013a

  18. Etude sur les tendons en materiaux composites et leur application aux ancrages postcontraints

    NASA Astrophysics Data System (ADS)

    Chennouf, Adil

    L'objectif general de la presente these est d'evaluer le comportement a l'arrachement et au fluage d'ancrages injectes constitues de tendons en materiaux composites afin d'etablir des recommandations plus appropriees et realistes pour le dimensionnement et la conception. Quatre types de tendons en materiaux composites, deux a base de fibres d'aramide et deux a base de fibres de carbone, ont ete utilises dans l'etude. Les travaux de recherche de cette these ont porte notamment sur: (I) Une caracterisation physique et mecanique des tendons en materiaux composites utilises dans l'etude. (II) Une etude en laboratoire sur les coulis de scellement. La premiere etape de cette etude a concerne le developpement d'un coulis de scellement performant adapte aux tendons en materiaux composites et a differentes situations d'injection. La seconde etape a traite des essais de caracterisations physique et mecanique du coulis de scellement developpe comparativement a trois coulis de scellement usuels d'un meme rapport E/L de 0,4. (III) Une etude sur des modeles reduits d'ancrages injectes. (IV) Une etude sur des modeles d'ancrages a grande echelle. La synthese de ces etudes a permis d'enoncer les principales conclusions suivantes: (1) Les valeurs moyennes des charges de rupture des tendons en materiaux composites ont ete de 1% a 29% superieures a celles specifiees par les manufacturiers. (2) L'etude sur les coulis de scellement a permis le developpement de coulis de ciment repondant aux criteres fixes, soient une grande stabilite, une bonne fluidite, une legere expansion et de bonnes caracteristiques mecaniques. (3) Les tendons en materiaux composites ont montre des contraintes d'adherence maximum superieures a celles des tendons en acier. (4) Le type de fibre, la configuration et le fini de surface des tendons en materiaux composites gouvernent leur resistance a l'adherence. (5) L'introduction de sable et d'autres ajouts comme les fines de silice et la poudre d'aluminium au coulis

  19. Deposition of radionuclides by fogwater on plants at Houdelaincourt, France

    NASA Astrophysics Data System (ADS)

    Tav, Jackie; Masson, Olivier; Burnet, Frédéric; De Visme, Anne; Paulat, Pascal; Bourrianne, Thierrry; Conil, Sébastien; Simon, Maxime

    2015-04-01

    After a nuclear accident like Fukushima, large quantities of radionuclides attached to particles are released in the atmosphere. Those particles can act as condensation nuclei to form fog droplets. To determine the radiological impact of fog droplets deposition on plants, an analysis of the fogwater radioactivity levels and a quantification of the fogwater deposition have been performed. To collect fogwater samples, a replica of the Caltech Active Strand Cloudwater Collector (Demoz et al. 1996) is implemented at the atmospheric research platform in Houdelaincourt (North-East region of France). This instrument allows air containing fog drops to be drawn through a cylinder by a fan. In this tube, rows of Teflon strands are collecting the drops by impaction. Other active collectors have been developed on the same principle with a tube and a mesh grid as the impaction surface. Passive collectors are also used; they consist of vertical strings surrounding a container where the drops are collected. Once the fogwater is collected, it is analyzed to determine the activity levels of gamma emitter radionuclides. In previous studies (Bourcier 2009) the mean level activity for cesium 137, beryllium 7 and lead 210 in rainwater at the Puy de DÙme have been previously estimated. A comparison between activity levels found in rainwater and in fogwater highlights the fact that fog deposition of radionuclides is far from negligible. At the same time a fog monitor FM-120 from DMT provides the size distribution of droplets from 1 to 30 microns. A visibility meter and a PVM from Gerber Scientific Inc. provide respectively the visibility and the liquid water content (LWC) to identify and characterize fog events. In order to quantify the deposition of water on plants, plastics plants were exposed to fog droplet deposition and weighed at the end of the event to measure the amount of water deposited. A second experiment was conducted, during which plastics plants were implemented on a

  20. Apercu des fautes eventuelles des anglophones Nord-Americains (Survey of Possible Errors of English-Speaking North Americans).

    ERIC Educational Resources Information Center

    LeBel, Jean-Guy

    This paper discusses the concept of error in the learning of the phonology of a second language and argues that the concept of error must be viewed as a positive element, an initiation of the process of successive approximations toward the correct phonetic realization. Based on the idea that interference between two languages generates a…

  1. SUR2 subtype (A and B)-dependent differential activation of the cloned ATP-sensitive K+ channels by pinacidil and nicorandil

    PubMed Central

    Shindo, Takashi; Yamada, Mitsuhiko; Isomoto, Shojiro; Horio, Yoshiyuki; Kurachi, Yoshihisa

    1998-01-01

    The classical ATP sensitive K+ (KATP) channels are composed of a sulphonylurea receptor (SUR) and an inward rectifying K+ channel subunit (BIR/Kir6.2). They are the targets of vasorelaxant agents called K+ channel openers, such as pinacidil and nicorandil.In order to examine the tissue selectivity of pinacidil and nicorandil, in vitro, we compared the effects of these agents on cardiac type (SUR2A/Kir6.2) and vascular smooth muscle type (SUR2B/Kir6.2) of the KATP channels heterologously expressed in HEK293T cells, a human embryonic kidney cell line, by using the patch-clamp method.In the cell-attached recordings (145 mM K+ in the pipette), pinacidil and nicorandil activated a weakly inwardly-rectifying, glibenclamide-sensitive 80 pS K+ channel in both the transfected cells.In the whole-cell configuration, pinacidil showed a similar potency in activating the SUR2B/Kir6.2 and SUR2A/Kir6.2 channels (EC50 of ∼2 and ∼10 μM, respectively). On the other hand, nicorandil activated the SUR2B/Kir6.2 channel >100 times more potently than the SUR2A/Kir6.2 (EC50 of ∼10 μM and >500 μM, respectively).Thus, nicorandil, but not pinacidil, preferentially activates the KATP channels containing SUR2B. Because SUR2A and SUR2B are diverse only in 42 amino acids at their C-terminal ends, it is strongly suggested that this short part of SUR2B may play a critical role in the action of nicorandil on the vascular type classical KATP channel. PMID:9692785

  2. Child homicide and neglect in France: 1991-2008.

    PubMed

    Makhlouf, F; Rambaud, C

    2014-01-01

    The aim of this study is to investigate epidemiological characteristics of the victims and the offenders in children homicide cases and to propose preventive measures. We retrospectively investigated homicides and deaths by neglect involving children aged 15 or less, which have been autopsied in the Department of Pathology and Legal Medicine of the Raymond Poincaré Hospital, Garches, France, during the 18-year period from 1991 to 2008. Cases included were analyzed for victims' age and gender, victim-assailant's relation, death cause and scenery, and offender's motivation. For the purposes of the study, victims were divided into four age groups: new born; infants (1-23 months); young children (2-5 years); and children (6-15 years). During the study period, 70 victims of homicide or fatal neglect were identified, which equates to a child homicide prevalence of 0.56 per 100,000 children per year. Slightly more than half of the victims (51.4%) were less than 1 year old. Neonaticide prevalence was 0.12 per 100,000 births with an equal distribution between genders. Neonates were most likely to be killed by their mothers while fathers were the most frequent assailants in both infants and children groups. Stepparents were involved in only one case. Familicide cases where children and spouses are killed were perpetrated only by fathers. The leading cause of death was blunt trauma (especially head trauma). In the neonaticide group, half of the victims died from passive neglect whereas gunshots were predominant in the children groups.

  3. Zinc and Its Isotopes in the Loire River Basin, France

    NASA Astrophysics Data System (ADS)

    Millot, R.; Desaulty, A. M.; Bourrain, X.

    2014-12-01

    The contribution of human activities such as industries, agriculture and domestic inputs, becomes more and more significant in the chemical composition of the dissolved load of rivers. Human factors act as a supplementary key process. Therefore the mass-balance for the budget of catchments and river basins include anthropogenic disturbances. The Loire River in central France is approximately 1010 km long and drains an area of 117,800 km2. In the upper basin, the bedrock is old plutonic rock overlain by much younger volcanic rocks. The intermediate basin includes three major tributaries flowing into the Loire River from the left bank: the Cher, the Indre and the Vienne rivers; the main stream flows westward and its valley stretches toward the Atlantic Ocean. Here, the Loire River drains the sedimentary series of the Paris Basin, mainly carbonate deposits. The lower Loire basin drains pre-Mesozoic basement of the Armorican Massif and its overlying Mesozoic to Cenozoic sedimentary deposits. The Loire River is one of the main European riverine inputs to the Atlantic ocean. Here we are reporting concentration and isotope data for Zn in river waters and suspended sediments from the Loire River Basin. In addition, we also report concentration and isotope data for the different industrial sources within the Loire Basin, as well as data for biota samples such as mussels and oysters from the Bay of Biscay and North Brittany. These organisms are known to be natural accumulators of metal pollutants. Zinc isotopic compositions are rather homogeneous in river waters with δ66Zn values ranging from 0.21 to 0.39‰. This range of variation is very different from anthropogenic signature (industrial and/or agriculture release) that displays δ66Zn values between 0.02 to 0.14‰. This result is in agreement with a geogenic origin and the low Zn concentrations in the Loire River Basin (from 0.8 to 6 µg/L).

  4. Hyperostosis frontalis interna in a Neandertal from Marillac (Charente, France).

    PubMed

    Garralda, María Dolores; Maureille, Bruno; Vandermeersch, Bernard

    2014-02-01

    The site of Marillac (Charente, France) has yielded an important stratigraphic sequence containing numerous Neandertal remains (some of them with peri-mortem manipulations) from lithofacies 2 (Quina Mousterian). This level has been correlated with MIS 4 and is associated with a TL date of 57,600 ± 4600 years BP (before present). The study of one of the cranial fragments (Marillac 3) revealed a grade 2 or Type B Hyperostosis frontalis interna (HFI), remodelling and altering the internal table of the thick frontal bone. This pathology has been analysed macroscopically together with radiography and sections made using a microscanner and a scanner. The development of the HFI is compared with published evidence for Sangiran 3 (Homo erectus), two other Neandertals (Forbes' Quarry and Shanidar 5), and several archaeological samples. Forbes' Quarry seems to display more advanced HFI than either Shanidar 5 or Marillac 3. The three Neandertals may be considered mature individuals (≥40 years) and it seems likely that the aetiology of this pathology may be associated with hormonal alterations, as has been suggested for past and extant populations. While the prevalence of HFI in contemporary post-menopausal women is well documented, the identification of HFI amongst males from several archaeological samples (Neanderthals, Ancient Egypt, Syrian Bronze Age or the Anasazi), with different stages of development, confirm that the pathology affected both sexes in past populations. Additional data and research are still needed to elucidate the etiopathogenesis of this illness and to better understand the relationship between environmental factors and their possible influences/consequences for the development of metabolic disorders in prehistoric populations. PMID:24491378

  5. Governing obesity policies from England, France, Germany and Scotland.

    PubMed

    Vallgårda, Signild

    2015-12-01

    Defining a phenomenon as a political problem could be considered a crucial part of any political process. Body weight, when categorised as obesity, has been defined as a political problem since the beginning of the 21st century and has entered the political agenda in many countries. In this article, I present a study of four plans from four Western European countries: England, France, Germany and Scotland, identifying how obesity is defined as a political issue. The questions addressed are: How is the development in the obesity prevalence explained and who is considered responsible for the development? What are the suggested remedies and who is considered responsible for acting? All plans state that obesity is a political issue because it causes health problems; in fact, weight is almost equated to health. The English and Scottish plans present a bio-political argument, characterising obesity as a serious threat to the countries' economies. So does the German plan, but not with the same emphasis. The plans portray people with obesity as being economically harmful to their fellow citizens. The French plan expresses another concern by focussing on the discrimination and stigmatization of obese people. All plans define the physical and food environment as a crucial factor in the obesity development, but only the Scottish Government is prepared to use statutory means towards industry and other actors to achieve change. The policies convey an unresolved dilemma: To govern or not to govern? The Governments want individuals to choose for themselves, yet they try to govern the populations to choose as the Governments find appropriate. The plans have a legitimising function, showing that the Governments take the issue seriously. Accordingly, in this case, the actual problematisations seem to be less crucial.

  6. Prevalence of Cryptosporidium infection in calves in France.

    PubMed

    Lefay, D; Naciri, M; Poirier, P; Chermette, R

    2000-03-28

    Two multicentre surveys were conducted in France to estimate the prevalence of Cryptosporidium infection in calves using qualitative ELISA for detection of Cryptosporidium coproantigens and oocysts. The first survey involved 4-12-day-old calves in six dairy-calf distribution centres, collecting calves from seven Administrative Regions (Aquitaine, Bretagne, Franche-Comté, Lorraine, Normandie, Nord, Pays de Loire). For each region, 20 calves were selected every month for 12 consecutive months (October 1995-September 1996). Prevalence of Cryptosporidium infection was 17.9% (Confidence Intervals (C.I.) 95%=[16.1%; 19.8%]) among the 1628 selected calves, of which only 5.3% had diarrhoea. The second survey conducted between November 1995 and May 1996 involved 4-21-day-old calves examined by veterinary practitioners who selected 189 livestock farms of dairy- or suckler-type in ten Administrative Departments (Allier, Cantal, Creuse, Doubs, Ille-et-Vilaine, Maine-et-Loire, Manche, Pas-de-Calais, Saône-et-Loire, Vendée). Cryptosporidia were detected in 105 (55.6%) of the farms. Among the 440 calves examined, of which 398 (90.5%) presented diarrhoea, cryptosporidia were found in 191 animals, i.e. a prevalence of 43.4% (C.I. 95%=[38. 8%; 48.0%]). Breed of calves and type of housing had very little impact on prevalence in this survey. Some regional variations could be noticed, even if cryptosporidia infection is widespread. Monthly variations could be related to seasonal peaks in calving with a lower infection rate during summer.

  7. Aldehyde measurements in indoor environments in Strasbourg (France)

    NASA Astrophysics Data System (ADS)

    Marchand, C.; Bulliot, B.; Le Calvé, S.; Mirabel, Ph.

    Formaldehyde and acetaldehyde concentrations have been measured in indoor environments of various public spaces (railway station, airport, shopping center, libraries, underground parking garage, etc.) of Strasbourg area (east of France). In addition, formaldehyde, acetaldehyde propionaldehyde and hexanal concentrations have been measured in 22 private homes in the same area. In most of the sampling sites, indoor and outdoor formaldehyde and acetaldehyde concentrations were measured simultaneously. Gaseous aldehydes levels were quantified by a conventional DNHP-derivatization method followed by liquid chromatography coupled to UV detection. Outdoor formaldehyde and acetaldehyde concentrations were both in the range 1-10 μg m -3, the highest values being measured at the airport and railway station. Indoor concentrations were strongly dependant upon the sampling sites. In homes, the average concentrations were 37 μg m -3 (living rooms) and 46 μg m -3 (bedrooms) for formaldehyde, 15 μg m -3 (living rooms) and 18 μg m -3 (bedrooms) for acetaldehyde, 1.2 μg m -3 (living rooms) and 1.6 μg m -3 (bedrooms) for propionaldehyde, 9 μg m -3 (living rooms) and 10 μg m -3 (bedrooms) for hexanal. However, concentrations as high as 123, 80 and 47 μg m -3 have been found for formaldehyde, acetaldehyde and hexanal respectively. In public spaces, the highest formaldehyde concentration (62 μg m -3) was found in a library and the highest concentration of acetaldehyde (26 μg m -3) in the hall of a shopping center. Additional measurements of formaldehyde and acetaldehyde were made inside a car both at rest or in a fluid or heavy traffic as well as in a room where cigarettes were smoked. Our data have been discussed and compared with those of previous studies.

  8. Space Radar Image of Rhine River, France and Germany

    NASA Technical Reports Server (NTRS)

    1994-01-01

    This spaceborne radar image shows a segment of the Rhine River where it forms the border between the Alsace region of northeastern France on the left and the Black Forest region of Germany on the right. The Rhine, one of the largest and most used waterways in central Europe, winds its way through five countries from the Swiss-Austrian Alps to the North Sea coast of the Netherlands. The river valley is densely populated, as seen in this image, which shows the French city of Strasbourg, the light blue and orange area in the upper left center; and the German cities of Kehl, across the river from Strasbourg and Offenburg, the bright area in right center. The fertile valley is famous for its wine production and most of the agricultural areas in the image, shown in purple patches, are vineyards. The light green areas are forest. Scientists can use radar images like this one to monitor the effects of urban and agricultural development on sensitive ecosystems such as the Rhine River valley. This image was acquired by the Spaceborne Imaging Radar-C/X-Band Synthetic Aperture Radar (SIR-C/X-SAR) onboard the space shuttle Endeavour on October 2, 1994. The image is 34.2 kilometers by 33.2 kilometers (21.2 miles by 20.6 miles) and is centered at 48.5 degrees north latitude, 7.7 degrees east longitude. North is toward the upper left. The colors are assigned to different radar frequencies and polarizations of the radar as follows: red is L-band, horizontally transmitted and received; green is L-band, horizontally transmitted, vertically received; and blue is C-band, horizontally transmitted, vertically received. SIR-C/X-SAR, a joint mission of the German, Italian and United States space agencies, is part of NASA's Mission to Planet Earth program.

  9. Reconstruction of the Provence Chain evolution, southeastern France

    NASA Astrophysics Data System (ADS)

    Bestani, L.; Espurt, N.; Lamarche, J.; Bellier, O.; Hollender, F.

    2016-06-01

    The Provence fold-and-thrust belt forms the eastern limit of the Pyrenean orogenic system in southeastern France. This belt developed during the Late Cretaceous-Eocene Pyrenean-Provence compression and was then deformed by Oligocene-Miocene Ligurian rifting events and Neogene to present-day Alpine compression. In this study, surface structural data, seismic profiles, and crustal-to-lithospheric-scale sequentially balanced cross sections contribute to the understanding of the dynamics of the Provence Chain and its long-term history of deformation. Balanced cross sections show that the thrust system is characterized by various structural styles, including deep-seated basement faults that affect the entire crust, tectonic inversions of Paleozoic-Mesozoic basins, shallower décollements within the sedimentary cover, accommodation zones, and salt tectonics. This study shows the prime control of the structural inheritance over a long period of time on the tectonic evolution of a geological system. This includes mechanical heterogeneities, such as Variscan shear zones, reactivated during Middle Cretaceous Pyrenean rifting between Eurasia and Sardinia. In domains where Mesozoic rifting is well marked, inherited basement normal faults and the thermally weak crust favored the formation of an inner thick-skinned thrust belt during Late Cretaceous-Eocene contraction. Here 155 km (~35%) of shortening was accommodated by inversion of north verging crustal faults, north directed subduction of the Sardinia mantle lithosphere, and ductile thickening of the Provence mantle lithosphere. During the Oligocene, these domains were still predisposed for the localized faulting of the Ligurian basin rifting and the seafloor spreading.

  10. Child homicide and neglect in France: 1991-2008.

    PubMed

    Makhlouf, F; Rambaud, C

    2014-01-01

    The aim of this study is to investigate epidemiological characteristics of the victims and the offenders in children homicide cases and to propose preventive measures. We retrospectively investigated homicides and deaths by neglect involving children aged 15 or less, which have been autopsied in the Department of Pathology and Legal Medicine of the Raymond Poincaré Hospital, Garches, France, during the 18-year period from 1991 to 2008. Cases included were analyzed for victims' age and gender, victim-assailant's relation, death cause and scenery, and offender's motivation. For the purposes of the study, victims were divided into four age groups: new born; infants (1-23 months); young children (2-5 years); and children (6-15 years). During the study period, 70 victims of homicide or fatal neglect were identified, which equates to a child homicide prevalence of 0.56 per 100,000 children per year. Slightly more than half of the victims (51.4%) were less than 1 year old. Neonaticide prevalence was 0.12 per 100,000 births with an equal distribution between genders. Neonates were most likely to be killed by their mothers while fathers were the most frequent assailants in both infants and children groups. Stepparents were involved in only one case. Familicide cases where children and spouses are killed were perpetrated only by fathers. The leading cause of death was blunt trauma (especially head trauma). In the neonaticide group, half of the victims died from passive neglect whereas gunshots were predominant in the children groups. PMID:24075615

  11. Respiratory viruses within homeless shelters in Marseille, France

    PubMed Central

    2014-01-01

    Background Homeless shelters are identified as places where humans are at high risk of acquiring respiratory disease. We previously reported the prevalence of the main respiratory diseases affecting a population of homeless in Marseille, France. Here, we investigated the prevalence of 10 respiratory viruses in a similar homeless population during 2 successive winter seasons. Findings Following a clinical examination, we collected nasal specimens from which the RT-PCR detection of 10 respiratory viruses was performed through snapshot investigations. Among the 265 patients included, 150 (56.6%) reported at least one respiratory symptom of which 13 (8.7%) had positive swabs for at least one respiratory virus, and 115 patients reported any respiratory symptom of which 10 (8.7%) had positive swabs for respiratory virus. Overall, 23 patients had positive swabs for at least one respiratory virus. Human rhinovirus (HRV) was the predominant virus (13 isolates) followed by enteroviruses (3), human metapneumovirus (2), human coronavirus OC43 (2), 229E virus (2) and human respiratory syncytial virus subtype B (1). Among the patients infected with HRV, 10 were collected during the same snapshot. Conclusions Although one half of the patients reported respiratory symptoms, the prevalence of respiratory viruses was within the range of that previously described in adult asymptomatic patients outside the homeless community. Most HRV-positive swabs were collected during the same snapshot suggesting a local outbreak. No influenza viruses were found despite the fact that one half of the patients were investigated during the peak of the seasonal influenza epidemic in Marseille. PMID:24499605

  12. Occupational exposure in the fluorescent lamp recycling sector in France

    SciTech Connect

    Zimmermann, François Lecler, Marie-Thérèse; Clerc, Frédéric; Chollot, Alain; Silvente, Eric; Grosjean, Jérome

    2014-07-15

    Highlights: • Chemical risks were assessed in the five fluorescent lamp recycling facilities. • The main hazardous agents are mercury vapors and dust containing lead and yttrium. • Exposure and pollutant levels were correlated with steps and processes. • All the stages and processes are concerned by worrying levels of pollutants. • We suggest recommendations to reduce chemical risk. - Abstract: The fluorescent lamp recycling sector is growing considerably in Europe due to increasingly strict regulations aimed at inciting the consumption of low energy light bulbs and their end-of-life management. Chemical risks were assessed in fluorescent lamp recycling facilities by field measurement surveys in France, highlighting that occupational exposure and pollutant levels in the working environment were correlated with the main recycling steps and processes. The mean levels of worker exposure are 4.4 mg/m{sup 3}, 15.4 μg/m{sup 3}, 14.0 μg/m{sup 3}, 247.6 μg/m{sup 3}, respectively, for total inhalable dust, mercury, lead and yttrium. The mean levels of airborne pollutants are 3.1 mg/m{sup 3}, 9.0 μg/m{sup 3}, 9.0 μg/m{sup 3}, 219.2 μg/m{sup 3}, respectively, for total inhalable dust, mercury, lead and yttrium. The ranges are very wide. Surface samples from employees’ skin and granulometric analysis were also carried out. The overview shows that all the stages and processes involved in lamp recycling are concerned by the risk of hazardous substances penetrating into the bodies of employees, although exposure of the latter varies depending on the processes and tasks they perform. The conclusion of this study strongly recommends the development of a new generation of processes in parallel with more information sharing and regulatory measures.

  13. An Extraordinary Gobioid Fish Fossil from Southern France

    PubMed Central

    Gierl, Christoph; Reichenbacher, Bettina; Gaudant, Jean; Erpenbeck, Dirk; Pharisat, André

    2013-01-01

    Background The classification of gobioid fishes is still under discussion. Several lineages, including the Eleotridae and Butidae, remain difficult to characterize because synapomorphies are rare (Eleotridae) or have not yet been determined (Butidae). Moreover, the fossil record of these groups is scarce. Results Exceptionally well-preserved fish fossils with otoliths in situ from uppermost Oligocene sediments (≈23–24 Mio. y. ago) in Southern France provide the most in-depth description of a fossil gobioid to date. The species was initially described as Cottus aries Agassiz, then transferred to †Lepidocottus Sauvage, and subsequently assigned to Gobius. Based on a comparative analysis of meristic, osteological and otolith data, this species most likely is a member of the family Butidae. This discovery is important because it represents the first record of a fossil butid fish based on articulated skeletons from Europe. Significance The Butidae and Eleotridae are currently distributed in W-Africa, Madagascar, Asia and Australia, but they do not appear in Europe and also not in the Mediterranean Sea. The new results indicate that several species of the Butidae thrived in Europe during the Oligocene and Early Miocene. Similar to the recent Butidae and Eleotridae, these fishes were adapted to a wide range of salinities and thrived in freshwater, brackish and marginal marine habitats. The fossil Butidae disappeared from Europe and the Mediterranean and Paratethys areas during the Early Miocene, due probably to their lack of competitiveness compared to other Gobioidei that radiated during this period of time. In addition, this study documents the great value of otoliths for gobioid systematics. PMID:23691158

  14. Improvement of gravity records at J9 Observatory, Strasbourg, France

    NASA Astrophysics Data System (ADS)

    Calvo, M.; Rosat, S.; Hinderer, J.; Rogister, Y. J.

    2013-12-01

    The Gravimetric Observatory J9 located near Strasbourg (France), is an historical site for solid earth tide recording. It was settled in the 1970s in a bunker and different kinds of gravimeters (spring, absolute and cryogenic meters) have been recording. Since the registration of the first series in late 1971 using a spring meter (Askania 206) the gravimeters and acquisition systems have been drastically improved, increasing the measurement accuracy by more than 10 times. We present here only the 3 gravimeters that have been recording for longer time in the observatory: a LaCoste-Romberg spring gravimeter (ET005) from 1973 to 1985, a GWR (TT70-T005) superconducting gravimeter from 1987 to 1996 and finally a GWR compact superconducting gravimeter (C026) still recording since 1996. We show the improvements obtained in terms of noise level from the oldest type to the newest one. We also study the sensitivity of each instrument and its temporal stability. For the 2 superconducting gravimeters, the stability of the scale factor which has been periodically checked on site with absolute gravity parallel records, is also studied. The results show that the use of long series of precise SG observations is a powerful tool to retrieve very low frequency signals, signals close in frequency, and small amplitude signals (e.g. tides generated by the third-degree potential). We merge the 2 series of SG data to take full advantage of its length. The long duration of almost 26 years will help us: to separate contributions of near frequencies (e.g. the annual and the Chandlerian components induced by the Earth's rotation); to exhibit very low frequency terms (e.g. long period tides) and to detect very weak signal that were hidden in the noise of shorter series.

  15. Hyperostosis frontalis interna in a Neandertal from Marillac (Charente, France).

    PubMed

    Garralda, María Dolores; Maureille, Bruno; Vandermeersch, Bernard

    2014-02-01

    The site of Marillac (Charente, France) has yielded an important stratigraphic sequence containing numerous Neandertal remains (some of them with peri-mortem manipulations) from lithofacies 2 (Quina Mousterian). This level has been correlated with MIS 4 and is associated with a TL date of 57,600 ± 4600 years BP (before present). The study of one of the cranial fragments (Marillac 3) revealed a grade 2 or Type B Hyperostosis frontalis interna (HFI), remodelling and altering the internal table of the thick frontal bone. This pathology has been analysed macroscopically together with radiography and sections made using a microscanner and a scanner. The development of the HFI is compared with published evidence for Sangiran 3 (Homo erectus), two other Neandertals (Forbes' Quarry and Shanidar 5), and several archaeological samples. Forbes' Quarry seems to display more advanced HFI than either Shanidar 5 or Marillac 3. The three Neandertals may be considered mature individuals (≥40 years) and it seems likely that the aetiology of this pathology may be associated with hormonal alterations, as has been suggested for past and extant populations. While the prevalence of HFI in contemporary post-menopausal women is well documented, the identification of HFI amongst males from several archaeological samples (Neanderthals, Ancient Egypt, Syrian Bronze Age or the Anasazi), with different stages of development, confirm that the pathology affected both sexes in past populations. Additional data and research are still needed to elucidate the etiopathogenesis of this illness and to better understand the relationship between environmental factors and their possible influences/consequences for the development of metabolic disorders in prehistoric populations.

  16. Governing obesity policies from England, France, Germany and Scotland.

    PubMed

    Vallgårda, Signild

    2015-12-01

    Defining a phenomenon as a political problem could be considered a crucial part of any political process. Body weight, when categorised as obesity, has been defined as a political problem since the beginning of the 21st century and has entered the political agenda in many countries. In this article, I present a study of four plans from four Western European countries: England, France, Germany and Scotland, identifying how obesity is defined as a political issue. The questions addressed are: How is the development in the obesity prevalence explained and who is considered responsible for the development? What are the suggested remedies and who is considered responsible for acting? All plans state that obesity is a political issue because it causes health problems; in fact, weight is almost equated to health. The English and Scottish plans present a bio-political argument, characterising obesity as a serious threat to the countries' economies. So does the German plan, but not with the same emphasis. The plans portray people with obesity as being economically harmful to their fellow citizens. The French plan expresses another concern by focussing on the discrimination and stigmatization of obese people. All plans define the physical and food environment as a crucial factor in the obesity development, but only the Scottish Government is prepared to use statutory means towards industry and other actors to achieve change. The policies convey an unresolved dilemma: To govern or not to govern? The Governments want individuals to choose for themselves, yet they try to govern the populations to choose as the Governments find appropriate. The plans have a legitimising function, showing that the Governments take the issue seriously. Accordingly, in this case, the actual problematisations seem to be less crucial. PMID:26618496

  17. How France launched its donation after cardiac death program.

    PubMed

    Antoine, C; Mourey, F; Prada-Bordenave, E

    2014-02-01

    On the basis of the literature and results presented at the 6th International Conference, donation after cardio-circulatory death provides a significant, practical, additional high quality source of transplantable organs. The vast majority of DCD are 'controlled' Maastricht category III donors. In 2010, the parliamentary information mission on the revision of the bioethics laws invited the Intensive Care Societies to debate and to make recommendations to implement controlled donation after circulatory death. They came to the conclusion that such retrieval is possible in France and insisted on the medical criteria that frame it: the writing of the medical procedures, the ethical aspects and the delay. The major recommendations of the ethics committees were firstly, The WLST decision is independent of the possibility of organ donation; secondly, the strict respect of "The dead donor and organ transplantation rule" and the updated national guidance for the WLST; thirdly, the drafting of a nationally agreed protocol defining the mandatory conditions to determine death and to perform procurement and transplantation. Organ donation after WLST will be authorised only in pilot centres with a locally agreed WLST policy including external second opinion and written transcript of the WLST decision, experienced intensive care staff, a local organ procurement coordination team familiar with DBD and DCD protocols and only in hospitals authorised for organ procurement. It is important to have an optimal and standardized national guidance to limit the known risk factors of graft failure (donor and recipient choice, warm and cold ischemia time), to increase acceptance by medical community and civil society and to improve results and allow more powerful analysis.

  18. US Astronomers Access to SIMBAD in Strasbourg, France

    NASA Technical Reports Server (NTRS)

    Eichhorn, G.; Oliverson, Ronald J. (Technical Monitor)

    2003-01-01

    During the last year the US SIMBAD Gateway Project continued to provide services like user registration to the US users of the SIMBAD database in France. Currently there are over 4300 US users registered. We also provided user support by answering questions from users and handling requests for lost passwords when still necessary. Even though almost all users now access SIMBAD without a password, based on hostnames/IP addresses, there are still some users that need individual passwords. We continued to maintain the mirror copy of the SIMBAD database on a server at SAO. This allows much faster access for the US users. During the past year we moved this mirror to a faster server to improve access for the US users. We again supported a demonstration of the SIMBAD database at the meeting of the American Astronomical Society in January. We provided support for the demonstration activities at the SIMBAD booth. We paid part of the fee for the SIMBAD demonstration. We continued to improve the cross-linking between the SIMBAD project and the Astrophysics Data System. This cross-linking between these systems is very much appreciated by the users of both the SIMBAD database and the ADS Abstract Service. The mirror of the SIMBAD database at SAO makes this connection faster for the US astronomers. We exchange information between the ADS and SIMBAD on a daily basis. The close cooperation between the CDS in Strasbourg and SAO, facilitated by this project, is an important part of the astronomy-wide digital library initiative. It has proven to be a model in how different data centers can collaborate and enhance the value of their products by linking with other data centers. We continue this collaboration in order to provide better services to both the US and European astronomical community. This collaboration is even more important in light of the developments for the Virtual Observatory projects in the different countries.

  19. Green space, social inequalities and neonatal mortality in France

    PubMed Central

    2013-01-01

    Background Few studies have considered using environmental amenities to explain social health inequalities. Nevertheless, Green spaces that promote good health may have an effect on socioeconomic health inequalities. In developed countries, there is considerable evidence that green spaces have a beneficial effect on the health of urban populations and recent studies suggest they can have a positive effect on pregnancy outcomes. To investigate the relationship between green spaces and the spatial distribution of infant mortality taking account neighborhood deprivation levels. Methods The study took place in Lyon metropolitan area, France. All infant deaths that occurred between 2000 and 2009 were geocoded at census block level. Each census block was assigned greenness and socioeconomic deprivation levels. The spatial–scan statistic was used to identify high risk cluster of infant mortality according to these neighborhood characteristics. Results The spatial distribution of infant mortality was not random with a high risk cluster in the south east of the Lyon metropolitan area (p<0.003). This cluster disappeared (p=0.12) after adjustment for greenness level and socioeconomic deprivation, suggesting that these factors explain part of the spatial distribution of infant mortality. These results are discussed using a conceptual framework with 3 hypothetical pathways by which green spaces may have a beneficial effect on adverse pregnancy outcomes: (i) a psychological pathway, (ii) a physiological disruption process and (iii) an environmental pathway. Conclusions These results add some evidence to the hypothesis that there is a relationship between access to green spaces and pregnancy outcomes but further research is required to confirm this. PMID:24139283

  20. Hailstorm forecast from stability indexes in Southwestern France

    NASA Astrophysics Data System (ADS)

    Melcón, Pablo; Merino, Andrés; Sánchez, José Luis; Dessens, Jean; Gascón, Estíbaliz; Berthet, Claude; López, Laura; García-Ortega, Eduardo

    2016-04-01

    Forecasting hailstorms is a difficult task because of their small spatial and temporal scales. Over recent decades, stability indexes have been commonly used in operational forecasting to provide a simplified representation of different thermodynamic characteristics of the atmosphere, regarding the onset of convective events. However, they are estimated from vertical profiles obtained by radiosondes, which are usually available only twice a day and have limited spatial representativeness. Numerical models predictions can be used to overcome these drawbacks, providing vertical profiles with higher spatiotemporal resolution. The main objective of this study is to create a tool for hail prediction in the southwest of France, one of the European regions where hailstorms have a higher incidence. The Association Nationale d'Etude et de Lutte contre les Fleáux Atmosphériques (ANELFA) maintains there a dense hailpad network in continuous operation, which has created an extensive database of hail events, used in this study as ground truth. The new technique is aimed to classify the spatial distribution of different stability indexes on hail days. These indexes were calculated from vertical profiles at 1200 UTC provided by WRF numerical model, validated with radiosonde data from Bordeaux. Binary logistic regression is used to select those indexes that best represent thermodynamic conditions related to occurrence of hail in the zone. Then, they are combined in a single algorithm that surpassed the predictive power they have when used independently. Regression equation results in hail days are used in cluster analysis to identify different spatial patterns given by the probability algorithm. This new tool can be used in operational forecasting, in combination with synoptic and mesoscale techniques, to properly define hail probability and distribution. Acknowledgements The authors would like to thank the CEPA González Díez Foundation and the University of Leon for its

  1. Intragenic single nucleotide polymorphism haplotype analysis of SUR1 mutations in familial hyperinsulinism.

    PubMed

    Glaser, B; Furth, J; Stanley, C A; Baker, L; Thornton, P S; Landau, H; Permutt, M A

    1999-01-01

    Familial hyperinsulinism (HI; MIM# 256450) is an autosomal recessive disorder of pancreatic beta-cell function, characterized by inadequate suppression of insulin secretion despite severe recurrent fasting hypoglycemia. Subtotal pancreatectomy is frequently required to prevent permanent neurologic sequelae. The incidence of HI in the Caucasian population is estimated at 1:50,000, however an apparent increased incidence among Ashkenazi Jews and Saudi Arabian Arabs has been reported. A locus for HI was assigned by linkage analyses to human chromosome 11p15.1. The sulfonylurea receptor (MIM# 600509, SUR1) and the potassium channel, inwardly rectifying, subfamily J member 11 (MIM# 600937, KIR6.2) genes, 2 components of the beta-cell K(ATP) channel, are clustered in this chromosomal region, and mutations in these genes have been implicated in HI. We previously demonstrated that two mutations in the SUR1 gene are present on approximately 88% of HI-associated chromosomes in Ashkenazi Jewish patients. Haplotype analysis with microsatellite markers flanking the gene revealed that one mutation (delF1388), reported only in Ashkenazi probands, occurred on two related extended haplotypes. By contrast, the second, more common mutation (3992-9g-->a) was associated with nine different intergenic haplotypes and has been reported in non-Jewish HI patients as well. In this study, we evaluated disease-associated chromosomes from 41 Ashkenazi Jewish and 2 non-Jewish HI patients carrying the 3992-9g-->a mutation by assessing haplotypes defined by nine common single nucleotide polymorphisms (SNPs), six in the SUR1 gene, and three in the KIR6.2 gene. Our results indicate that all 54 chromosomes carrying the 3992-9g-->a mutation in the Jewish patients appear to have originated from one founder mutation, whereas the same mutation on chromosomes from non-Jewish patients originated independently. Furthermore, our findings have implications concerning the HI-associated chromosomes on which no

  2. Instrumentation pour la spectroscopie laser sur faisceau d'ions rapides

    NASA Astrophysics Data System (ADS)

    Bazin, Marc

    Devant l'emergence des technologies exploitant l'infiniment petit, la spectroscopie atomique et moleculaire devient de plus en plus incontournable pour comprendre precisement les mecanismes quantiques impliques dans l'interaction des molecules. C'est le cas notamment de la nanotechnologie, de la dynamique reactionnelle des gaz a effet de serre ou simplement de l'identification des molecules constituant certains objets de l'astrophysique. Bien qu'un travail considerable soit deja accompli pour comprendre la dissociation ou la formation des molecules simples, il reste a vaincre la complexite des mecanismes impliques lorsque les molecules possedent plus de trois noyaux. Parmi les rares techniques de spectroscopie a tres haute resolution (jusqu'a la structure hyperfine), la spectroscopie laser sur faisceaux d'ions rapides est une methode experimentale eprouvee depuis trois decennies environ. Cette methode spectroscopique fournit des resultats comptant parmi les meilleurs pour obtenir des constantes moleculaires precises et permettre la reduction du spectre moleculaire. Une particularite remarquable de notre instrument est la possibilite d'enregistrer le signal de fragmentation moleculaire par laser via les etats de predissociation de la molecule etudiee. Notre contribution a ete d'ameliorer et de moderniser l'equipement existant. Nous avons augmente la resolution spectrale de notre instrument. Nous avons atteint notre principal objectif, a savoir, la possibilite d'acquerir des spectres selon deux modes : par detection du signal synchronisee sur le faisceau laser module en frequence ou par detection du signal directement par comptage. Cette derniere methode est une premiere sur ce type d'instrument et son principal interet a ete d'obtenir une meilleure mesure de l'elargissement de raie. Nous sommes parvenus a mettre clairement en evidence l'elargissement de raie avec la puissance laser en utilisant la methode de detection par comptage direct. La fluorescence induite par

  3. Living in France. A Brief Introduction or Review of the Culture and Language of France for Visitors, Students and Business Travelers. Third revised Edition.

    ERIC Educational Resources Information Center

    Hawkinson, Anni; Moran, Patrick R.

    The guide offers practical information on various aspects of daily living in France, including: money; food; restaurants; hotels; postal and telecommunications services; transportation; shopping; health and medical care; safety and security; tipping; electricity; measurement and clothing size conversions; greetings and leave-takings; names,…

  4. Developpement et apprentissage dans la nouvelle politique educative en France (Development and Training in the New Policy for Education in France).

    ERIC Educational Resources Information Center

    Herman-Bredel, Josiana

    1993-01-01

    Discusses France's 1989 New Policy for Education (NPE), which identifies three ways of preventing academic failure: school policies stressing family involvement and instructional continuity; reorganization of primary education into three training cycles; and assessment of student competencies. Considers NPE's position on knowledge development.…

  5. In situ and laboratory investigations of fluid flow through an argillaceous formation at different scales of space and time, Tournemire tunnel, southern France

    NASA Astrophysics Data System (ADS)

    Boisson, Jean-Yves; Bertrand, Lucien; Heitz, Jean-François; Golvan, Yann Moreau-Le

    2001-01-01

    In the context of a research and development program on waste disposal, an experimental site (Tournemire tunnel, Aveyron, France) was selected by the French Institute for Nuclear Protection and Safety (IPSN) in order to undertake studies on potential fluid flow at different scales of space and time within a 250-m-thick argillaceous formation. The argillite has a low natural water content ( 3-5%) and very low radii access porosity. Diffusion (tritiated water) coefficients (1×10-12 to 2×10-11 m2/s) and hydraulic conductivities derived from different types of laboratory tests (10-14 to 10-13 m/s) are characteristics of a very low-permeable rock. In situ hydraulic tests (including long-term hydraulic-head measurements) were used to obtain values for hydraulic head and hydraulic conductivity at a scale of 1-10 m (10-13 to 10-11 m/s). Despite uncertainties on these data (due to a scale factor, presence of fissures, and possible artefacts due to hydro-chemo-mechanical coupling), it is expected that fluid flow is essentially governed by diffusion processes. Identification of possible natural flows at larger scales of time and space was investigated using natural isotopic tracers from interstitial fluids. Modelling, based on the deuterium profile along the clay formation and assuming pure diffusion processes, provides estimations of possible flow times. However, lack of knowledge concerning the past geological evolution of the site and the possible role of a fracture network do not permit reduction of uncertainties on these estimations at this stage. Résumé. Dans le cadre de son programme de recherche et développement sur les stockages de déchets, un site expérimental (tunnel de Tournemire, Aveyron, France) a été sélectionné par l'Institut de Protection et Sûreté Nucléaire (IPSN) pour conduire des études sur les possibilités de transferts de fluides à différentes échelles de temps et d'espace au sein d'une formation argileuse de 250 m d'épaisseur. L

  6. Grossesse sur cicatrice de césarienne: à propos d'un cas et revue de la literature

    PubMed Central

    Lachiri, Boutaina; Zazi, Abdelgheni; Benkerroum, Zineb; Hafidi, Moulay Rachid; Kouach, Jaouad; Rahali, Driss Moussaoui; Dehayni, Mohamed

    2015-01-01

    La grossesse sur cicatrice de césarienne est une forme rare de grossesse ectopique qui engage le pronostic vital et fonctionnel utérin par hémorragie ou par rupture utérine précoce. Nous rapportons le cas d'une grossesse ectopique sur cicatrice de césarienne diagnostiquée à 11 semaines d'aménorrhée suite à une aspiration blanche pour grossesse arrêtée chez une patiente de 43 ans porteuse d'un utérus bi-cicatriciel. A travers cette observation ainsi qu'une revue de la littérature les auteurs vont essayer de mettre le point sur les méthodes diagnostiques et thérapeutiques de cette entité rare afin d'améliorer la prise en charge. PMID:26213603

  7. Misleading averages on couples j. (French Title: Moyennes trompeuses sur des couples j )

    NASA Astrophysics Data System (ADS)

    Thorel, J. C.

    2010-09-01

    From 1919 to 1920, the equatorial with a 35 cm aperture which is part of the private observatory of Robert JONCKHEERE located at Hem in France undergoes a repair in the workshop of Prin-Gauthier in Paris. During that period, no measure of double stars could be done. Yet, several means are published. We present an analysis of these means and a few others which were established during another period of inactivity in astronomy.

  8. Photographic Snow-cover Monitoring on St Sorlin Glacier, France.

    NASA Astrophysics Data System (ADS)

    Gerbaux, M.; Genthon, C.; Dedieu, J.; Balestrieri, J.

    2004-12-01

    Like most other glaciers in the Alps, the St Sorlin glacier (french Alps, 45.16°N, 6.16°E, 2900 m asl mean elevation and 3km2 of surface area) has been retreating fast in the last 20 years. To understand the meteorological factors responsible for this retreat, and to tentatively predict glaciers evolution in a changing (warming) climate, we use a distributed snow/ice mass and energy balance model derived from the CROCUS snow model (Météo-France). There is no direct meteorological observation on or near St Sorlin glacier yet, and hourly meteorology to force the snow/ice model is obtained from disaggregated meteorological analyses. The model is found to reproduce the St Sorlin mass balance of the last 20 years as obtained from field glaciological measurements and stereophotographic reconstructions. The model is also found to reproduce the interannual variations of the equilibrium line as determined from optical satellite imagery. Because of the albedo feedback involved, it is also important to verify that the summer snow/ice transition on the glacier is correctly simulated. Thus, an automated photographic system was set up facing St Sorlin glacier to monitor the evolution of the snow cover. The system was installed on the 13th of July 2004 and is still in operation at time of abstract writing. Digital photographies are taken every 4 hours, permitting so far at least one non-obstructed (rain, fog) picture per day. The first pictures in the series show an almost fully snow-covered glacier while the latest ones show bare ice up to the highest parts of the glacier. Snow is occasionally deposited during precipitation events but hardly last more than 3 days. Snow line position is deduced from pictures using a DEM with georeferenced points visible on pictures. It should then be compared with the modelled one. The automated photographic system provides not only snow cover to check snow/ice model results at seasonal time-scales, but also qualitative meteorological

  9. EPIPAGE 2: a preterm birth cohort in France in 2011

    PubMed Central

    2014-01-01

    Background Children born at low gestational ages face a range of risks and number of neonates surviving very preterm birth is increasing. We present the objectives and methods of a French national cohort of very and moderately preterm children, the EPIPAGE 2 study. It aims to examine short- and long-term outcomes of very preterm children and their determinants. Methods/Design Eligible participants for this prospective population-based study include all infants live born or stillborn and all terminations of pregnancy between 22 and 31 completed weeks of gestation in all the maternity units in 25 French regions. In addition, a sample of moderate preterm births, i.e. births and late terminations at 32–34 weeks, was included in the same regions. In all, 7804 babies (stillbirths and live births) and terminations of pregnancy out of 8400 eligible births in France in 2011 that were either very (22–31 weeks) or moderately preterm (32–34 weeks) were included. Data on pregnancy, delivery, and neonatal events were extracted from the obstetric and neonatal records. The follow-up will collect information at corrected ages of one and 2 years and at 5, 8, and 12 years of age. Of the 4467 children discharged alive from the hospital and eligible for follow-up, 155 (4%) families refused further follow-up and 22 died before one-year of age. Finally, 4290 were included in the follow-up. Eight additional projects investigating specific hypotheses among subsamples of the cohort by collecting specific data in addition to the core cohort data are being conducted to investigate 1) diagnosis of histologic chorioamnionitis, 2) early biomarkers of child health, 3) attitudes of care for extremely preterm infants, 4) painful procedures in neonatal intensive care units, 5) neonatal MRI cerebral abnormalities and their relation to executive functions, 6) associations between early gut colonization and early and late onset diseases, 7) impact of neonatal nutrition on child development

  10. Suicide Among Farmers in France: Occupational Factors and Recent Trends.

    PubMed

    Bossard, Claire; Santin, Gaëlle; Guseva Canu, Irina

    2016-01-01

    Numerous studies have found agricultural workers, including farmers, at elevated risk of suicide, and socioeconomic conditions have been suggested as one of the important determinants of this mortality cause. The real agricultural income per worker in Europe increased steadily from 2005 to 2007 and then fell by 1.8% in 2008 and by 11.6% in 2009. This drop was particularly pronounced in France. Repeated cross-sectional studies were conducted to investigate suicide mortality rates among French farmers in 2007-2009. The study population included all French farmers enrolled yearly in the compulsory Agricultural Social Security and Health Insurance (CCMSA). Most of the mean of 500,164 subjects per year were men (68%). National cause-specific mortality rates were used to calculate standardized mortality ratios (SMRs) and associated 95% confidence intervals (95% CIs) for both genders and for each of the 3 years. During the 3-year study period, 2,769 men and 997 women died. Suicide accounted for 417 of the men's (15%) and 68 of the women's (6.8%) deaths. Hanging was the most frequent method of suicide for both. Compared with the general population, the increased rate of suicide deaths among male farmers was 28% in 2008 and 22% in 2009. This increased rate was particularly high among those aged 45-54 years (31%) and 55-64 years (47%) in 2008 (and in the 55-64-year-old group in 2009 (64%). Two specific types of farming activity were associated with increased suicide mortality rates in both 2008 and 2009: dairy cattle farming (SMR = 1.56 [95% CI: 1.09-2.15] and SMR=1.47 [95% CI: 1.01-2.04]) and beef cattle farming (SMR = 2.27 [95% CI: 1.59-3.10] and SMR = 1.57 [95% CI: 1.01-2.27]). These results may be useful for a better understanding of the situation from an epidemiological standpoint and for improving suicide prevention policies in this particular population. PMID:27409004

  11. How an Anglo-American methodology took root in France.

    PubMed

    Laszlo, Pierre

    2011-01-01

    French organic chemistry had a strong nationalistic bent in the immediate aftermath to World War II. It continued to bask in the glow of the pre-World War I Nobel prize awarded jointly in 1912 to Victor Grignard and Paul Sabatier. In addition, the influence of the two mandarins then in power, Charles Prévost at the Sorbonne and Albert Kirrmann, a Dean in Strasbourg who would be called upon as vice-director at the École normale supérieure in Paris, saw to it that the only theory of organic reactions, admissible in the classroom and in the laboratory, was Prévost's. As Mary Jo Nye has shown, a wall was erected against penetration of the ideas of the British school of Ingold and Hughes. Mechanistic chemistry, as was being vigorously studied by the contemporary Anglo-American physical organic chemists, was 'persona non grata' in France. Publication by Bianca Tchoubar, in 1960, of "Les mécanismes réactionnels en chimie organique" opened a breach. The irony was for Dr. Tchoubar, a militant member of the Communist Party and a lady of fierce opinions, to have become a propagandist for the Anglo-American school of mechanistic studies. Truth for her overruled political propaganda. Her little book was revolutionary in the French context of the times. Together with the GECO (Groupe d'étude de chimie organique) summer conferences pioneered by Guy Ourisson after his return from Harvard, it ushered in the new ideas. This historical essay, based on an in-depth study of Tchoubar's book, will include a portrait of this remarkable woman scientist. It will delve at some length into the renewal of French science initiated by De Gaulle's government after his return to power in 1958. The tension in the French scientific establishment of the sixties reflected two opposed versions of nationalism, the one conservative, Malthusian, inner-directed, the other forward-looking, eager for the recovery of national status, seeing a strong French science as a means for asserting national

  12. Trends of eutrophication in the Loire River (France)

    NASA Astrophysics Data System (ADS)

    Minaudo, Camille; Moatar, Florentina; Gassama, Nathalie; Curie, Florence

    2016-04-01

    The Loire River (France) was known to be sensible to eutrophication at the end of the 1970s, especially in its lower reaches with extreme phytoplankton growth (chlorophyll a concentration up to 250 μg L-1 in summer). During the 80s and 90s, the Loire estuary was often in state of anoxia in summer, as a result of the biodegradation of large quantities of labile organic matter. In this context, this work aimed at identifying clearly its eutrophication trajectories since the European environmental measures undertook in the early 1990s, and aimed at studying the physical and chemical causes and consequences of phytoplankton blooms. The long-term water quality time-series carried out by the national authorities allowed to identify the Loire River eutrophication trends since 1980. Since the extreme conditions in the early 1990s, phytoplankton developments in summer were divided 3-fold in the Loire River and in the main tributaries, synchronously with the generalized reduction 2-fold of bioavailable phosphorous. This was mostly attributable to the improvement of P treatment in the upstream waste water treatment plants. Thus, controlling and limiting P point sources greatly limited the magnitude of phytoplankton blooms (from 150 to 60 μg Chl. a L-1 between 1990 and 2012 in the lower Loire reaches). These trajectories highly changed the spatio-temporal dynamics of nutrients. Organic carbon (C-org) was not measured within the regular survey, however, based on some strong relationships between particulate C-org, suspended solids and pigments concentrations measured recently within a daily scale survey (2012-2014), C-org fluxes of the past could be reasonably assessed and it was estimated that 50% of the total C-org fluxes entering the estuarine zone in summer had autochthonous origins in the 80s and 90s against 20% during the period 2012-2014. Eutrophication has decreased in the freshwater system but keeps affecting the coastal zone, especially because algal species in

  13. How an Anglo-American methodology took root in France.

    PubMed

    Laszlo, Pierre

    2011-01-01

    French organic chemistry had a strong nationalistic bent in the immediate aftermath to World War II. It continued to bask in the glow of the pre-World War I Nobel prize awarded jointly in 1912 to Victor Grignard and Paul Sabatier. In addition, the influence of the two mandarins then in power, Charles Prévost at the Sorbonne and Albert Kirrmann, a Dean in Strasbourg who would be called upon as vice-director at the École normale supérieure in Paris, saw to it that the only theory of organic reactions, admissible in the classroom and in the laboratory, was Prévost's. As Mary Jo Nye has shown, a wall was erected against penetration of the ideas of the British school of Ingold and Hughes. Mechanistic chemistry, as was being vigorously studied by the contemporary Anglo-American physical organic chemists, was 'persona non grata' in France. Publication by Bianca Tchoubar, in 1960, of "Les mécanismes réactionnels en chimie organique" opened a breach. The irony was for Dr. Tchoubar, a militant member of the Communist Party and a lady of fierce opinions, to have become a propagandist for the Anglo-American school of mechanistic studies. Truth for her overruled political propaganda. Her little book was revolutionary in the French context of the times. Together with the GECO (Groupe d'étude de chimie organique) summer conferences pioneered by Guy Ourisson after his return from Harvard, it ushered in the new ideas. This historical essay, based on an in-depth study of Tchoubar's book, will include a portrait of this remarkable woman scientist. It will delve at some length into the renewal of French science initiated by De Gaulle's government after his return to power in 1958. The tension in the French scientific establishment of the sixties reflected two opposed versions of nationalism, the one conservative, Malthusian, inner-directed, the other forward-looking, eager for the recovery of national status, seeing a strong French science as a means for asserting national

  14. Suicide Among Farmers in France: Occupational Factors and Recent Trends.

    PubMed

    Bossard, Claire; Santin, Gaëlle; Guseva Canu, Irina

    2016-01-01

    Numerous studies have found agricultural workers, including farmers, at elevated risk of suicide, and socioeconomic conditions have been suggested as one of the important determinants of this mortality cause. The real agricultural income per worker in Europe increased steadily from 2005 to 2007 and then fell by 1.8% in 2008 and by 11.6% in 2009. This drop was particularly pronounced in France. Repeated cross-sectional studies were conducted to investigate suicide mortality rates among French farmers in 2007-2009. The study population included all French farmers enrolled yearly in the compulsory Agricultural Social Security and Health Insurance (CCMSA). Most of the mean of 500,164 subjects per year were men (68%). National cause-specific mortality rates were used to calculate standardized mortality ratios (SMRs) and associated 95% confidence intervals (95% CIs) for both genders and for each of the 3 years. During the 3-year study period, 2,769 men and 997 women died. Suicide accounted for 417 of the men's (15%) and 68 of the women's (6.8%) deaths. Hanging was the most frequent method of suicide for both. Compared with the general population, the increased rate of suicide deaths among male farmers was 28% in 2008 and 22% in 2009. This increased rate was particularly high among those aged 45-54 years (31%) and 55-64 years (47%) in 2008 (and in the 55-64-year-old group in 2009 (64%). Two specific types of farming activity were associated with increased suicide mortality rates in both 2008 and 2009: dairy cattle farming (SMR = 1.56 [95% CI: 1.09-2.15] and SMR=1.47 [95% CI: 1.01-2.04]) and beef cattle farming (SMR = 2.27 [95% CI: 1.59-3.10] and SMR = 1.57 [95% CI: 1.01-2.27]). These results may be useful for a better understanding of the situation from an epidemiological standpoint and for improving suicide prevention policies in this particular population.

  15. Ongoing pharmaceutical reforms in France: implications for key stakeholder groups.

    PubMed

    Sermet, Catherine; Andrieu, Veronique; Godman, Brian; Van Ganse, Eric; Haycox, Alan; Reynier, Jean-Pierre

    2010-01-01

    The rapid rise in pharmaceutical costs in France has been driven by new technologies and the growing prevalence of chronic diseases as well as considerable prescribing freedom and choice of physician among patients. This has led to the introduction of a number of reforms and initiatives in an attempt to moderate expenditure whilst ensuring universal coverage and rewarding innovation. These reforms include accelerating access to and granting average European prices for new innovative drugs, delisting drugs where there are concerns over their value and instigating rebates for excessive prescribing. Alongside this, ongoing initiatives to improve the quality and efficiency of prescribing include programmes to enhance generic prescribing and dispensing as well as to reduce antibacterial and anxiolytic/hypnotic prescribing. However, there have been few publications documenting the impact of specific reforms on the overall costs and quality of care, which have been exacerbated by compartmentalization of budgets. Estimates suggest savings of over 27 million euro/year by decreasing antibacterial prescribing, 450 million euro/year by not reimbursing ineffective drugs, 670 million euro/year from pharmaceutical company rebates and approximately 1 billion euro/year from increased prescribing and dispensing of generics (year 2003-7 values). Additional savings of at least 1.5 billion euro/year are seen as being possible from increased use of generics such as generic proton pump inhibitors, statins (HMG-CoA reductase inhibitors) and ACE inhibitors instead of current branded products such as angiotensin II type 1 receptor antagonists (angiotensin receptor blockers [ARBs]). Delisting drugs when there are concerns about their value provides an example to other countries with currently limited demand-side measures. Other possible examples include price : volume agreements and multifaceted campaigns to enhance generic prescribing and dispensing and reduce antibacterial prescribing

  16. Occupational cancer in France: epidemiology, toxicology, prevention, and compensation.

    PubMed Central

    Aubrun, J C; Binet, S; Bozec, C; Brochard, P; Dimerman, S; Fontaine, B; Guénel, P; Luce, D; Martinet, Y; Moulin, J J; Mur, J M; Pietruszynski, M; Vallayer, C

    1999-01-01

    This article is a description of the current situation in France with regard to occupational cancer: research, prevention, and occupation. Toxicologic experiments are carried out using (italic)in vitro(/italic) and (italic)in vivo(/italic) tests, particularly using transgenic mice. Several epidemiologic studies have been conducted over the last decades: population-based case-control studies; mortality studies and cancer incidence studies carried out in historical cohorts of workers employed in the industry; and case-control studies nested in occupational cohorts. French ethical aspects of toxicologic and epidemiologic studies are described. The results thus obtained are used to establish regulations for the prevention and the compensation of cancers attributable to occupational exposure. This French regulation for prevention of occupational cancer involves several partners: (italic)a(/italic)) the states authorities, including labor inspectors, responsible for preparing and implementing the labor legislation and for supervising its application, particularly in the fields of occupational health and safety and working conditions; (italic)b(/italic)) the Social Security Organisation for the analysis of present or potential occupational risks based on tests, visits in plants, complaints or requests from various sources, and statistics. These activities are performed within the framework of the general French policy for the prevention of occupational cancer. This organization includes the National Institute for Research and Safety, particularly involved in research in the various fields of occupational risks--animal toxicology, biologic monitoring, exposure measurements epidemiology, psychology, ergonomy, electronic systems and machineries, exposure to chemicals, noise, heat, vibration, and lighting; and (italic)c(/italic)) companies where the regulation defines the role of the plant manager, the occupational physician, and the Health, Safety and Working Conditions

  17. Predictive mapping of the natural flow regimes of France

    NASA Astrophysics Data System (ADS)

    Snelder, Ton H.; Lamouroux, Nicolas; Leathwick, John R.; Pella, Hervé; Sauquet, Eric; Shankar, Ude

    2009-06-01

    SummaryHydrologic variability is important in sustaining a variety of ecological processes in streams and rivers. Natural flow regime classifications group streams and rivers that are relatively homogeneous with respect to flow variability and have been promoted as a method of defining units for management of river flows. Although there has been considerable interest in classifying natural flow regimes, there has been less emphasis given to developing accurate methods of extrapolating these classifications to locations without flow data. We developed a method of mapping flow regime classes using boosted regression trees (BRT) that automatically fits non-linear functions and interactions between explanatory variables of flow regimes, both of which can be expected when comparing responses between complex systems such as watersheds. A natural flow regimes classification of continental France was developed from cluster analysis of 157 hydrological indices derived from 763 gauging stations representing unmodified flows. BRT models were used to predict the likelihood of gauging stations belonging to each class based on the watershed characteristics. These models were used to extrapolate the natural flow regime classification to all segments of a national river network. The performance of the BRT models were compared with other methods of assigning locations to flow regime classes, including the use of geographically contiguous regions, linear discriminant analysis (LDA) and classification and regression trees (CART). The "fitted" misclassification rate (associated with model fits) for assignment based on the BRT models was 13% whereas the fitted misclassification rates for geographically contiguous regions, LDA and CART were 52%, 44% and 39% respectively. A "predictive" misclassification rate (calculated for new cases) was estimated for assignments based on the BRT, LDA and CART models using cross validation analysis. For assignment based on the BRT models, the mean

  18. The Holocene separation of Jersey from France: the microfossil evidence

    NASA Astrophysics Data System (ADS)

    Consolaro, Chiara; Hart, Malcolm; Chambers, Paul; Evans, Graham; Nichols, Ralph; Smart, Christopher; Whittaker, John

    2014-05-01

    More than fifty marine boreholes have been drilled into the sea bed between France and the east coast of Jersey and these are being used to plan the route of a new electricity cable. The cores provide a comprehensive coverage of an Holocene sedimentary succession and core OVC-18 is being used as a reference because it contains a near-complete record of the transition from a terrestrial environment, with peats and plant beds, to inter-tidal mud flats and, eventually, marine sediments with abundant marine fossils and highly significant occurrences of the calcareous red alga known as maërl. This core, therefore, contains a near-complete record of mid-late Holocene sea level rise through to the invasion of the slipper limpet Crepidula in 1962. Almost all of the samples contain well-preserved assemblages of foraminifera and ostracods that allow the reconstruction of a range of sub-environments through to fully marine. Below the terrestrial sediments in core OVC-18 is a thickness of carbonate-rich, fossiliferous, marine sands that may be of mid-Eocene age or derived from pre-existing Eocene sediments. The Baie du Mont-St-Michel, in which Jersey is located, is macro-tidal with an exceptionally large tidal range which probably developed quite early in the Holocene. The large tides are responsible for the significant numbers of transported marine foraminifera that are found in samples of saltmarsh and estuarine sediments. The upper saltmarsh environment is represented by the first 15-20 cm of muds immediately overlying a well-developed peat and contain a diagnostic benthic assemblage that includes Trochammina inflata and Jadammina macrescens. The overlying estuarine sediments are characterised by an assemblage dominated by Elphidium spp. and Ammonia spp.. The dating of this Holocene peat and the overlying marine sediments provides an accurate chronology of sea level rise around Jersey, although a crustal subsidence rate of -4 mm/year must be used to increase the impact of

  19. Holocene climate variability in south-western France

    NASA Astrophysics Data System (ADS)

    Oliveira, D.; Naughton, F.; Trigo, R.; Rodrigues, T.; Jouanneau, J.-M.; Weber, O.

    2012-04-01

    Vegetation and climate changes in western France/northern Spain are documented for the last c. 9000 cal. yr BP in a well dated shelf core, KS05-10, retrieved in the southwestern margin of the Bay of Biscay (Basque country) (43°22'765N, 2°16'744W). The continuous high resolution pollen record shows orbital and suborbital climate fluctuations similar to those noticed for the North Atlantic region and Greenland. A long-term Pinus, Quercus and Corylus forest reduction follows the cooling trend in Greenland and the general decrease of mid-latitude summer insolation until approximately 350 yr cal. BP. Within the millennial scale variability, the southwestern Bay of Biscay pollen record shows 6 main phases: The first phase, c. 9000 and 6600 cal. yr BP, is marked by a Pinus and deciduous Quercus forest with Corylus, indicating a humid and temperate climate. During the phase, c. 6600 - 4500 cal. yr BP, the pollen record shows a stable period of rich, mixed Quercus forest. During this interval occurred the establishment of Alnus, Ulmus, Tilia, Fraxinus excelsior-type and Fagus trees and the reduction of Pinus forest. This vegetation assemblage probably indicates an increase in moisture in relatively mild conditions. Fagus became continuously present in the region after c. 4500 c. cal. yr BP in agreement with what have been noticed by continental pollen sequences. An important contraction of Pinus, deciduous Quercus and Corylus forest occur after c. 3600 cal. yr BP. This evolution is contemporaneous to the maximum expansion of Fagus and the increase of heaths, which may be linked to a weakening of seasonality and more humid summer conditions. A strong forest reduction, involving all trees except pine, and a marked spread of herbaceous plants took place after c. 1400 cal. years BP. The presence of Juglans, Cerealia type and Castanea after c. 550 cal. yr BP and the re-expansion of Pinus after c. 350 cal. yr BP testify the increasing role played by the human activity in the

  20. [Management of congenital toxoplasmosis in France: current data].

    PubMed

    Garcia-Méric, Patricia; Franck, Jacqueline; Dumon, Henri; Piarroux, Renaud

    2010-05-01

    of age. Furthermore no consensus exists about the duration of postnatal treatment (3 months in Denmark versus 12 months in France). A multicenter randomized controlled trial is necessary to assess the efficacy of postnatal treatment and determine its duration. A surveillance system was set up in 2007 by the National Reference Center for Toxoplasmosis to determine the perinatal burden of this infection and to assess the national policy. PMID:19926248

  1. Effet de la composition des materiaux composites sur la caracterisation et detection par ondes de Lamb

    NASA Astrophysics Data System (ADS)

    Ostiguy, Pierre-Claude

    Les matériaux composites sont de plus en plus utilisés en aéronautique. Leurs excellentes propriétés mécaniques et leur faible poids leur procurent un avantage certain par rapport aux matériaux métalliques. Ceux-ci étant soumis à diverses conditions de chargement et environnementales, ils sont suceptibles de subir plusieurs types d'endommagements, compromettant leur intégrité. Des méthodes fiables d'inspection sont donc nécessaires pour évaluer leur intégrité. Néanmoins, peu d'approches non destructives, embarquées et efficaces sont présentement utilisées. Ce travail de recherche se penche sur l'étude de l'effet de la composition des matériaux composites sur la détection et la caractérisation par ondes guidées. L'objectif du projet est de développer une approche de caractérisation mécanique embarquée permettant d'améliorer la performance d'une approche d'imagerie par antenne piézoélectriques sur des structures composite et métalliques. La contribution de ce projet est de proposer une approche embarquée de caractérisation mécanique par ultrasons qui ne requiert pas une mesure sur une multitude d'échantillons et qui est non destructive. Ce mémoire par articles est divisé en quatre parties, dont les parties deux A quatre présentant les articles publiés et soumis. La première partie présente l'état des connaissances dans la matière nécessaires à l'acomplissement de ce projet de maîtrise. Les principaux sujets traités portent sur les matériaux composites, propagation d'ondes, la modélisation des ondes guidées, la caractérisation par ondes guidées et la surveillance embarquée des structures. La deuxième partie présente une étude de l'effet des propriétés mécaniques sur la performance de l'algorithme d'imagerie Excitelet. L'étude est faite sur une structure isotrope. Les résultats ont démontré que l'algorithme est sensible à l'exactitude des propriétés mécaniques utilisées dans le modèle. Cette

  2. Les enjuex éthiques entourant la recherche en santé sur les enfants

    PubMed Central

    2008-01-01

    RÉSUMÉ La recherche en santé est un devoir moral parce qu’elle est la base des soins probants prodigués par tous les dispensateurs de soins. Des politiques et des règlements précis régissent la tenue des recherches sur des humains. Il faut procéder à une évaluation éthique d’un projet de recherche donné avant de pouvoir l’entreprendre. La recherche sur les enfants pose d’énormes défis en matière de consentement éclairé et d’assentiment, de vulnérabilité et de potentiel de conflit d’intérêts (CDI). Les chercheurs en santé pédiatrique devraient prôner la participation des enfants à la recherche, tout en se montrant attentifs à en limiter les risques.

  3. Adsorption de gaz sur les materiaux microporeux modelisation, thermodynamique et applications

    NASA Astrophysics Data System (ADS)

    Richard, Marc-Andre

    2009-12-01

    Nos travaux sur l'adsorption de gaz dans les materiaux microporeux s'inscrivent dans le cadre des recherches visant a augmenter l'efficacite du stockage de l'hydrogene a bord des vehicules. Notre objectif etait d'etudier la possibilite d'utiliser l'adsorption afin d'ameliorer l'efficacite de la liquefaction de l'hydrogene des systemes a petite echelle. Nous avons egalement evalue les performances d'un systeme de stockage cryogenique de l'hydrogene base sur la physisorption. Comme nous avons affaire a des plages de temperatures particulierement etendues et a de hautes pressions dans la region supercritique du gaz, nous avons du commencer par travailler sur la modelisation et la thermodynamique de l'adsorption. La representation de la quantite de gaz adsorbee en fonction de la temperature et de la pression par un modele semi-empirique est un outil utile pour determiner la masse de gaz adsorbee dans un systeme mais egalement pour calculer les effets thermiques lies a l'adsorption. Nous avons adapte le modele Dubinin-Astakhov (D-A) pour modeliser des isothermes d'adsorption d'hydrogene, d'azote et de methane sur du charbon actif a haute pression et sur une grande plage de temperatures supercritiques en considerant un volume d'adsorption invariant. Avec cinq parametres de regression (incluant le volume d'adsorption Va), le modele que nous avons developpe permet de tres bien representer des isothermes experimentales d'adsorption d'hydrogene (de 30 a 293 K, jusqu'a 6 MPa), d'azote (de 93 a 298 K, jusqu'a 6 MPa) et de methane (de 243 a 333 K, jusqu'a 9 MPa) sur le charbon actif. Nous avons calcule l'energie interne de la phase adsorbee a partir du modele en nous servant de la thermodynamique des solutions sans negliger le volume d'adsorption. Par la suite, nous avons presente les equations de conservation de la niasse et de l'energie pour un systeme d'adsorption et valide notre demarche en comparant des simulations et des tests d'adsorption et de desorption. En plus de l

  4. The optimization research of the multi-response problems based on the SUR.

    PubMed

    Su, Haitao; Yao, Hong Mei; Zeng, Hui

    2015-03-01

    In the optimization design of products and processes in the biological medicine, we need to consider multiple characteristics of quality simultaneously, namely multi-response problems, multi-response optimization design can improve the quality of the products effectively, and realize enormous economic benefits and so multi-response optimization design is showing a more and more important role in continuous quality improvement activities. But usually there is no specific set of input variables to make all the response variables be optimal, and the traditional multi-response surface method cannot solve the correlation problem between multi-responses and regression model problem effectively. Because we can make a better fitting model and solve the problem of the correlation between the response variables at the same time with SUR method, this thesis uses the SUR method to model the relationship between each response and control variables, and makes predictions; confirms the satisfaction function of each response and the overall satisfaction function; combines with practical problems of a company in biological medicine field named SX to conduct empirical research, this thesis confirms the optimal factor level combination with the overall satisfaction function in the end, thus solves the multi-response optimization problems.

  5. Volvulus du grêle sur paquet d’ascaris: à propos d’un cas

    PubMed Central

    Diouf, Cheikh; Kane, Ahmed; Ndoye, Ndeye Aby; Ndour, Oumar; Faye-Fall, Aimé Lakh; Fall, Mbaye; Alumeti, Désiré Munyali; Ngom, Gabriel

    2016-01-01

    Nous rapportons un cas exceptionnel de volvulus nécrosé de l'intestin grêle dû à des ascaris adultes chez un enfant de 7 ans. A l'admission, l'enfant présentait le tableau d'occlusion intestinale qui évoluait depuis deux jours avec altération de l'état général. La radiographie de l'abdomen sans préparation retrouvait des niveaux hydroaériques de type grêlique et un aspect tigré évoquant le diagnostic d'une occlusion intestinale haute sur masse abdominale. Après la réanimation, le traitement chirurgical consistait en une laparotomie qui avait retrouvé un volvulus nécrosé de l'iléon terminale contenant des ascaris adultes. Une résection du grêle sur environ un mètre emportant le segment nécrosé suivie d'une iléostomie était réalisée. L'évolution a été favorable, l'anastomose iléo-colique fut réalisée quatre semaines plus tard. Au recul de deux ans l'enfant est indemne de tout symptôme. PMID:27795803

  6. Visual Analysis and Dissemination of Scientific Literature Collections with SurVis.

    PubMed

    Beck, Fabian; Koch, Sebastian; Weiskopf, Daniel

    2016-01-01

    Bibliographic data such as collections of scientific articles and citation networks have been studied extensively in information visualization and visual analytics research. Powerful systems have been built to support various types of bibliographic analysis, but they require some training and cannot be used to disseminate the insights gained. In contrast, we focused on developing a more accessible visual analytics system, called SurVis, that is ready to disseminate a carefully surveyed literature collection. The authors of a survey may use our Web-based system to structure and analyze their literature database. Later, readers of the survey can obtain an overview, quickly retrieve specific publications, and reproduce or extend the original bibliographic analysis. Our system employs a set of selectors that enable users to filter and browse the literature collection as well as to control interactive visualizations. The versatile selector concept includes selectors for textual search, filtering by keywords and meta-information, selection and clustering of similar publications, and following citation links. Agreement to the selector is represented by word-sized sparkline visualizations seamlessly integrated into the user interface. Based on an analysis of the analytical reasoning process, we derived requirements for the system. We developed the system in a formative way involving other researchers writing literature surveys. A questionnaire study with 14 visual analytics experts confirms that SurVis meets the initially formulated requirements.

  7. Evaluation des connaissances des parents sur les bronchiolites aiguës

    PubMed Central

    Gueddari, Widad; Tazi, Abderrahmane; Ouardi, Amine; Nani, Samira; Zineddine, Abdelhadi

    2014-01-01

    Les infections respiratoires (IR) constituent la deuxième cause de mortalité infantile au Maroc, dû en partie à l'absence d'information et de sensibilisation. Le but de ce travail était d’évaluer les connaissances des parents sur la bronchiolite aiguë, infection respiratoire très fréquente. Nous avons réalisé une enquête basée sur un questionnaire, auprès de parents de nourrissons consultants pour toux, avec ou sans gêne respiratoire. 180 parents ont été inclus dans l’étude. Les parents pensaient que l'infection respiratoire était secondaire au climat froid (96%); seuls 4% ont évoqué une origine infectieuse. Aucun des parents ne savait que le lavage des mains était un moyen de prévention de la transmission. Les parents ont majoritairement répondu que la kinésithérapie respiratoire ne servait à rien (65%), et qu'elle était nocive (24.5%). Ce manque de connaissances fondamentales en matière d'IR et de bronchiolite en particulier, devrait inciter à entreprendre un programme de sensibilisation PMID:25328606

  8. Implementation of tsunami disaster prevention measures in the municipality of San Rafael del Sur, Nicaragua

    NASA Astrophysics Data System (ADS)

    Strauch, W.; Talavera, E.; Acosta, N.; Sanchez, M.; Mejia, E.

    2007-05-01

    The Nicaraguan Pacific coast presents considerable tsunami risk. On September 1, 1992, a tsunami caused enormous damage in the infrastructure and killed more than 170 people. A pilot project was conducted between 2006 and 2007 in the municipality of San Rafel del Sur, area of Masachapa, The project included multiple topics of tsunami prevention measures and considering the direct participation of the local population, as: -General education on disaster prevention, participative events; -Investigation of awareness level and information needs for different population groups; -Specific educational measures in the schools; -Publication of brochures, calendars, news paper articles, radio programs, TV spots -Development of local tsunami hazard maps, 1:5,000 scale; (based on previous regional tsunami hazard mapping projects and local participation) -Development of a tsunami warning plan; -Improvements of the national tsunami warning system. -Installation of sirens for tsunami warning -Installation of tsunami signs, indicating hazardous areas, evacuation routes, safe places; -Realization of evacuation drills in schools. Based on the experiences gained in Masachapa it is planned to run similar projects in other areas along the Nicaraguan Pacific coast. In the project participated the local municipality and local stakeholders of San Rafael del Sur, Ministry of Education, National Police, Nicaraguan Red Cross, Ministry of Health, Ministry of Tourism, Nicaraguan Geosciences Institute (INETER), National System for Disaster Prevention (SINAPRED), Swiss Agency for Development and Cooperation (SDC). It was financed by SDC and INETER.

  9. Cancer du sein sur tissu mammaire ectopique: à propos de 2 cas

    PubMed Central

    Haddad, Houssam; Bourhaleb, Zouhour; El Harroudi, Tijani; Mezouar, Loubna; El Hfid, Mohamed

    2012-01-01

    Le cancer du sein sur tissu mammaire ectopique est une tumeur rare qui représente 0,2 à 0,6% de l′ensemble des cancers du sein. Les auteurs en rapportent 2 cas pris en charge dans 2 centres d′oncologie marocains. Il s′agit de 2 patientes âgées de 31 ans et 47 ans présentant un cancer du sein sur tissu mammaire ectopique en situation axillaire. Une tumorectomie avec curage ganglionnaire axillaire homolatéral a été réalisée chez les 2 patientes dont une après une chimiothérapie néoadjuvante. Le traitement adjuvant a compris une chimiothérapie, radiothérapie puis une hormonothérapie. Après un recul de 12 mois et 20 mois respectivement, les 2 patientes sont en rémission complète. PMID:23330041

  10. Socioeconomic Segregation in Large Cities in France and the United States.

    PubMed

    Quillian, Lincoln; Lagrange, Hugues

    2016-08-01

    Past cross-national comparisons of socioeconomic segregation have been undercut by lack of comparability in measures, data, and concepts. Using IRIS data from the French Census of 2008 and the French Ministry of Finance as well as tract data from the American Community Survey (2006-2010) and the U.S. Department of Housing and Urban Development Picture of Subsidized Households, and constructing measures to be as similar as possible, we compare socioeconomic segregation in metropolitan areas with a population of more than 1 million in France and the United States. We find much higher socioeconomic segregation in large metropolitan areas in the United States than in France. We also find (1) a strong pattern of low-income neighborhoods in central cities and high-income neighborhoods in suburbs in the United States, but varying patterns across metropolitan areas in France; (2) that high-income persons are the most segregated group in both countries; (3) that the shares of neighborhood income differences that can be explained by neighborhood racial/ethnic composition are similar in France and the United States; and (4) that government-assisted housing is disproportionately located in the poorest neighborhoods in the United States but is spread across many neighborhood income levels in France. We conclude that differences in government provision of housing assistance and levels of income inequality are likely important contributing factors to the Franco-U.S. difference in socioeconomic segregation. PMID:27393232

  11. Socioeconomic Segregation in Large Cities in France and the United States.

    PubMed

    Quillian, Lincoln; Lagrange, Hugues

    2016-08-01

    Past cross-national comparisons of socioeconomic segregation have been undercut by lack of comparability in measures, data, and concepts. Using IRIS data from the French Census of 2008 and the French Ministry of Finance as well as tract data from the American Community Survey (2006-2010) and the U.S. Department of Housing and Urban Development Picture of Subsidized Households, and constructing measures to be as similar as possible, we compare socioeconomic segregation in metropolitan areas with a population of more than 1 million in France and the United States. We find much higher socioeconomic segregation in large metropolitan areas in the United States than in France. We also find (1) a strong pattern of low-income neighborhoods in central cities and high-income neighborhoods in suburbs in the United States, but varying patterns across metropolitan areas in France; (2) that high-income persons are the most segregated group in both countries; (3) that the shares of neighborhood income differences that can be explained by neighborhood racial/ethnic composition are similar in France and the United States; and (4) that government-assisted housing is disproportionately located in the poorest neighborhoods in the United States but is spread across many neighborhood income levels in France. We conclude that differences in government provision of housing assistance and levels of income inequality are likely important contributing factors to the Franco-U.S. difference in socioeconomic segregation.

  12. Methodological proposals for estimating the price of climate in France

    NASA Astrophysics Data System (ADS)

    Joly, D.; Brossard, T.; Cardot, H.; Cavailhes, J.; Hilal, M.; Wavresky, P.

    2009-09-01

    A current project linking economists, geographers and mathematicians evaluates the price of climate in France. The economic data are mainly from housing surveys conducted by the INSEE. It consists in a total of 9,640 buyers of single-detached houses, 2,658 buyers of apartments, 3,447 tenants of single-detached houses and 8,615 tenants of apartments. Each transaction is located in space by X-Y geographical coordinates. The climatic data are derived from the Meteo-France data base (normal 1970-2000). They are related to (1) mean annual temperature, (2) mean temperature for January and July, (3) number of days with temperatures of less than -5 °C in January and more than 30 °C in July, (4) mean monthly rainfall, (5) rainfall in January and July, (6) number of days' precipitation in January and July. These data are recorded by a network of scattered weather stations. A raster GIS composed by ten data layers derived from a DEM and remote sensing images at 250 m resolution is used to initiate interpolations. Four types of interpolation techniques were tested. First we used regressions between climatic data (variables to be explained) and explanatory variables stored into the GIS. Second we used ordinary kriging; third a double step method linking regression and then kriging of the regression residuals. Finally we used a local interpolation method. Based on standard deviation values obtained by cross validation and R² values, the comparison between the four methods shows that the last one reduces the residuals to the minimum and explains the maximum of variance. It was retained in our project to compute continuous field of the climatic data. The predicted values are then merged with the housing survey data. We use the hedonic price method (Rosen, 1974) to determine the price of climatic attributes, which are capitalized in land rents. Three econometric methods are used: a fixed-effects model estimated by OLS or PLS method and a mixed model with random intercepts. The

  13. Context and dating of Aurignacian vulvar representations from Abri Castanet, France.

    PubMed

    White, Randall; Mensan, Romain; Bourrillon, Raphaëlle; Cretin, Catherine; Higham, Thomas F G; Clark, Amy E; Sisk, Matthew L; Tartar, Elise; Gardère, Philippe; Goldberg, Paul; Pelegrin, Jacques; Valladas, Hélène; Tisnérat-Laborde, Nadine; de Sanoit, Jacques; Chambellan, Dominique; Chiotti, Laurent

    2012-05-29

    We report here on the 2007 discovery, in perfect archaeological context, of part of the engraved and ocre-stained undersurface of the collapsed rockshelter ceiling from Abri Castanet, Dordogne, France. The decorated surface of the 1.5-t roof-collapse block was in direct contact with the exposed archaeological surface onto which it fell. Because there was no sedimentation between the engraved surface and the archaeological layer upon which it collapsed, it is clear that the Early Aurignacian occupants of the shelter were the authors of the ceiling imagery. This discovery contributes an important dimension to our understanding of the earliest graphic representation in southwestern France, almost all of which was discovered before modern methods of archaeological excavation and analysis. Comparison of the dates for the Castanet ceiling and those directly obtained from the Chauvet paintings reveal that the "vulvar" representations from southwestern France are as old or older than the very different wall images from Chauvet.

  14. VEB-1 Extended-spectrum beta-lactamase-producing Acinetobacter baumannii, France.

    PubMed

    Naas, Thierry; Coignard, Bruno; Carbonne, Anne; Blanckaert, Karine; Bajolet, Odile; Bernet, Claude; Verdeil, Xavier; Astagneau, Pascal; Desenclos, Jean-Claude; Nordmann, Patrice

    2006-08-01

    VEB-1 extended-spectrum beta-lactamase-producing Acinetobacter baumannii was responsible for an outbreak in hospitals in France. A national alert was triggered in September 2003 when 4 hospitals reported clusters of A. baumannii infection with similar susceptibility profiles. Case definitions and laboratory guidelines were disseminated, and prospective surveillance was implemented; strains were sent to a single laboratory for characterization and typing. From April 2003 through June 2004, 53 hospitals reported 290 cases of A. baumannii infection or colonization; 275 isolates were bla(VEB-1)-positive and clonally related. Cases were first reported in 5 districts of northern France, then in 10 other districts in 4 regions. Within a region, interhospital spread was associated with patient transfer. In northern France, investigation and control measures led to a reduction of reported cases after January 2004. The national alert enabled early control of new clusters, demonstrating the usefulness of early warning about antimicrobial drug resist.

  15. Capture-recapture method for estimating annual incidence of imported dengue, France, 2007-2010.

    PubMed

    La Ruche, Guy; Dejour-Salamanca, Dominique; Bernillon, Pascale; Leparc-Goffart, Isabelle; Ledrans, Martine; Armengaud, Alexis; Debruyne, Monique; Denoyel, Gérard-Antoine; Brichler, Ségolène; Ninove, Laetitia; Desprès, Philippe; Gastellu-Etchegorry, Marc

    2013-11-01

    Imported dengue cases pose the public health risk for local circulation in European areas, especially southeast France, where the Aedes mosquito is established. Using a capture-recapture method with Chao's estimator, we estimated the annual incidence of dengue fever and the completeness of existing mandatory notification and laboratory network surveillance systems. During 2007-2010, >8,300 cases with laboratory evidence of recent dengue infection were diagnosed. Of these cases, 4,500 occurred in 2010, coinciding with intense epidemics in the French West Indies. Over this 4-year period, 327 cases occurred in southeast France during the vector activity period. Of these, 234 cases occurred in 2010, most of them potentially viremic. Completeness of the mandatory notification and laboratory network systems were ≈10% and 40%, respectively, but higher in southeast areas during May-November (32% and 69%, respectively). Dengue surveillance systems in France provide complementary information that is essential to the implementation of control measures.

  16. Determinants of differentials in pneumonia mortality in the UK and France.

    PubMed

    ul Haq, Rizwan; Rivers, Patrick; Umar, Muhammad

    2014-01-01

    Pneumonia is one of the major causes of death in the world. Age-adjusted mortality from pneumonia in the United Kingdom was three times higher than it was in France in 2004. The purpose of this article is to find the underlying determinants of pneumonia mortality differences between these two countries. The main research question is "what are the determinants of pneumonia mortality in the UK and France?" Reviewing the underlying determinants of health inequalities, we expected that behavioral factors, environmental factors, and the health care system would account for the differences, but they do not actually account for much of the differences in Pneumonia mortality between the UK and France. The main difference is due to data quality problems particularly relating to diagnosis and certification in both countries. PMID:25223162

  17. Current process and future path for health economic assessment of pharmaceuticals in France

    PubMed Central

    Toumi, Mondher; Rémuzat, Cécile; El Hammi, Emna; Millier, Aurélie; Aballéa, Samuel; Chouaid, Christos; Falissard, Bruno

    2015-01-01

    The Social Security Funding Law for 2012 introduced the Economic and Public Health Assessment Committee (Commission Evaluation Economique et de Santé Publique, or CEESP) in the Social Security Code as a specialised committee affiliated with the Haute Autorité de Santé in charge of providing recommendations and health economic opinions. This article provides an in-depth description of the CEESP's structure and working methods, and analyses the impact of health economic assessment on market access of drugs in France. It also points out the areas of uncertainty and the conflicting rules following the introduction of the health economic assessment in France. The authors also provide their personal opinion on the likely future of health economic assessment of drugs in France, including the possible merge of the CEESP and the Transparency Committee, the implementation of a French threshold, and the extension of health economic assessment to a larger number of products. PMID:27123173

  18. Impact de la preparation des anodes crues et des conditions de cuisson sur la fissuration dans des anodes denses

    NASA Astrophysics Data System (ADS)

    Amrani, Salah

    La fabrication de l'aluminium est realisee dans une cellule d'electrolyse, et cette operation utilise des anodes en carbone. L'evaluation de la qualite de ces anodes reste indispensable avant leur utilisation. La presence des fissures dans les anodes provoque une perturbation du procede l'electrolyse et une diminution de sa performance. Ce projet a ete entrepris pour determiner l'impact des differents parametres de procedes de fabrication des anodes sur la fissuration des anodes denses. Ces parametres incluent ceux de la fabrication des anodes crues, des proprietes des matieres premieres et de la cuisson. Une recherche bibliographique a ete effectuee sur tous les aspects de la fissuration des anodes en carbone pour compiler les travaux anterieurs. Une methodologie detaillee a ete mise au point pour faciliter le deroulement des travaux et atteindre les objectifs vises. La majorite de ce document est reservee pour la discussion des resultats obtenus au laboratoire de l'UQAC et au niveau industriel. Concernant les etudes realisees a l'UQAC, une partie des travaux experimentaux est reservee a la recherche des differents mecanismes de fissuration dans les anodes denses utilisees dans l'industrie d'aluminium. L'approche etait d'abord basee sur la caracterisation qualitative du mecanisme de la fissuration en surface et en profondeur. Puis, une caracterisation quantitative a ete realisee pour la determination de la distribution de la largeur de la fissure sur toute sa longueur, ainsi que le pourcentage de sa surface par rapport a la surface totale de l'echantillon. Cette etude a ete realisee par le biais de la technique d'analyse d'image utilisee pour caracteriser la fissuration d'un echantillon d'anode cuite. L'analyse surfacique et en profondeur de cet echantillon a permis de voir clairement la formation des fissures sur une grande partie de la surface analysee. L'autre partie des travaux est basee sur la caracterisation des defauts dans des echantillons d'anodes crues

  19. Prevalence of infection with Toxoplasma gondii in landrace and mixed breed pigs slaughtered in Baja California Sur state, Mexico

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Purpose We performed a cross-sectional study to determine the seroprevalence of Toxoplasma gondii infection in 308 domestic pigs slaughtered in La Paz, Baja California Sur State, Mexico using the modified agglutination test (MAT, cut off 1:25). Results Forty (13%) of the 308 pigs were seropositive ...

  20. Electrokinetic bioprocessing under microgravity in France as illustrated by space bioseparation: A programme initiated in France and in cooperation with Belgium and Spain

    NASA Astrophysics Data System (ADS)

    Bozouklian, H.; Sanchez, V.; Clifton, M.; Marsal, O.; Esterle, A.

    The use of electrokinetic phenomena should prove to be a promising bioseparation technique especially as an application of bioprocessing under microgravity. Therefore, a bioseparation Research and Development programme involving several research teams has been under way for three years in France. Based upon the results of this fundamental research, a programme is now proposed for the development of an automated process chain making it possible to obtain biological macromolecules of high purity under microgravity. This Space Bio Separation programme received the Eureka label at the 6th Ministerial Eureka conference. The project will last six years. It will involve the cooperation of several scientific and industrial partners in France, in Spain and in Belgium. The programme includes the development and validation of three different bioseparation facilities for space.

  1. Effets de la pollution de l’air sur la santé

    PubMed Central

    Abelsohn, Alan; Stieb, Dave M.

    2011-01-01

    Résumé Objectif Faire connaître aux médecins de famille les effets de la pollution atmosphérique sur la santé et indiquer quels conseils donner aux patients vulnérables pour qu’ils soient moins exposés. Sources de l’information On a consulté MEDLINE à l’aide des termes relatifs à la pollution atmosphérique et à ses effets indésirables. On a révisé les articles en anglais publiés entre janvier 2008 et décembre 2009. La plupart des études contenaient des preuves de niveau II. Principal message Au Canada, la pollution de l’air extérieur cause une morbidité et une mortalité importantes. Elle peut affecter le système respiratoire (exacerbation de l’asthme et de la maladie pulmonaire obstructive chronique) et le système cardiovasculaire (déclencher l’arythmie, l’insuffisance cardiaque et les AVC). La cote air santé (CAS) est un nouvel outil de communication mis au point par Santé Canada et Environnement Canada qui indique sur une échelle de 1 à 10, le risque pour la santé causé par la pollution atmosphérique. La CAS est largement diffusée dans les médias et cet outil pourrait être utile au médecin de famille pour inciter les patients à haut risque (comme ceux qui souffrent d’asthme, de maladie pulmonaire obstructive chronique ou d’insuffisance cardiaque) à réduire leur exposition à la pollution atmosphérique. Conclusion Le médecin de famille peut se servir de la CAS et de ses messages sur la santé pour enseigner aux asthmatiques et aux autres patients à risque élevé la façon de réduire les risques pour la santé causés par la pollution atmosphérique.

  2. An epidemiological and genetic study of facial clefting in France. I. Epidemiology and frequency in relatives.

    PubMed Central

    Bonaiti, C; Briard, M L; Feingold, J; Pavy, B; Psaume, J; Migne-Tufferaud, G; Kaplan, J

    1982-01-01

    The frequencies of cleft lip with or without cleft palate (CL(P)) and isolated cleft palate (CP) have been estimated in France to be 0.082% and 0.035%, respectively, after exclusion of malformation syndromes. A genetic and epidemiological study has been carried out on 468 patients with CL(P) and 163 with CP. The results are given in detail and some specific points are discussed: the apparently low incidence in France, the relationship between sex ratio and abortion rates, the maternal effects, and the possibility of an association between CL(P) and CP. PMID:7200146

  3. Recent periurban growth in the Ile-de-France: forms and causes.

    PubMed

    Baccaini, B

    1998-01-01

    "The population of France's ¿old' urban centres has stopped increasing and urban growth is now concentrated in communes which until very recently were rural.... [The author] presents a detailed analysis of the process of growth of the economically active periurban population of the Ile-de-France. It is based on recent census data, and divides the periurban into two concentric zones and four geographical sectors. The examination of the individual characteristics of the economically active population, and the geographical origin of the newcomers, reveals the existence of an important phenomenon: the increasing social segregation of the urban and periurban populations." (EXCERPT)

  4. Evaluation of the smoking ban in public places in France one year and five years after its implementation: Findings from the ITC France survey.

    PubMed

    Fong, Geoffrey T; Craig, Lorraine V; Guignard, Romain; Nagelhout, Gera E; Tait, Megan K; Driezen, Pete; Kennedy, Ryan David; Boudreau, Christian; Wilquin, Jean-Louis; Deutsch, Antoine; Beck, François

    2013-05-01

    France implemented a comprehensive smoke-free policy in public places in February 2007 for workplaces, shopping centres, airports, train stations, hospitals and schools. On January 2008, it was extended to meeting places (bars, restaurants, hotels, casinos, nightclubs). This paper evaluates France's smoke-free law based on the International Tobacco Control Policy Evaluation Project in France (the ITC France Project), which conducted a cohort survey of approximately 1,500 smokers and 500 non-smokers before the implementation of the laws (Wave 1, conducted December 2006 to February 2007) and two waves after the implementation (Wave 2, conducted between September-November 2008; and Wave 3, conducted between September-December 2012). Results show that the smoke-free law led to a very significant and near total elimination of indoor smoking in key venues such as bars (from 95.9% to 3.7%) and restaurants (from 64.7% to 2.3%) at Wave 2, which was sustained four years later at Wave 3 (1.4% in restaurants; 6.6% in bars). Smoking in workplaces declined significantly after the law (from 42.6% to 19.3%), which continued to decline at Wave 3 (to 12.8%). Support for the smoke-free law increased significantly after their implementation and continued to increase at Wave 3 (among smokers for bars and restaurants; among smokers and non-smokers for workplaces). The findings demonstrate that smoke-free policies that are implemented in ways consistent with the Guidelines for Article 8 of the WHO Framework Convention on Tobacco Control (WHO FCTC) lead to substantial and sustained reductions in tobacco smoke in public places while also leading to high levels of support by the public.

  5. Case Study on Teaching Materials for Spanish Language and Culture Classes for Migrant Children in France. (Part I, Lyon-Paris, France) The CDCC's Project No. 7: "The Education and Cultural Development of Migrants".

    ERIC Educational Resources Information Center

    Dabene, Louise

    As part of the Spanish government's attempt to provide cultural and linguistic education for the sizable Spanish population in France, it organized the design of instructional materials especially suited to the 64,614 children of Spanish migrant workers living in rural and urban France. The materials were intended for use by primary and lower…

  6. Late Cardiac Events after Childhood Cancer: Methodological Aspects of the Pan-European Study PanCareSurFup

    PubMed Central

    Feijen, Elizabeth A. M.; Font-Gonzalez, Anna; van Dalen, Elvira C.; van der Pal, Helena J. H.; Reulen, Raoul C.; Winter, David L.; Kuehni, Claudia E.; Haupt, Riccardo; Alessi, Daniela; Byrne, Julianne; Bardi, Edit; Jakab, Zsuzsanna; Grabow, Desiree; Garwicz, Stanislaw; Jankovic, Momcilo; Levitt, Gill A.; Skinner, Roderick; Zadravec Zaletel, Lorna; Hjorth, Lars; Tissing, Wim J. E.; de Vathaire, Florent; Hawkins, Mike M.; Kremer, Leontien C. M.

    2016-01-01

    Background and Aim Childhood cancer survivors are at high risk of long-term adverse effects of cancer and its treatment, including cardiac events. The pan-European PanCareSurFup study determined the incidence and risk factors for cardiac events among childhood cancer survivors. The aim of this article is to describe the methodology of the cardiac cohort and nested case-control study within PanCareSurFup. Methods Eight data providers in Europe participating in PanCareSurFup identified and validated symptomatic cardiac events in their cohorts of childhood cancer survivors. Data on symptomatic heart failure, ischemia, pericarditis, valvular disease and arrhythmia were collected and graded according to the Criteria for Adverse Events. Detailed treatment data, data on potential confounders, lifestyle related risk factors and general health problems were collected. Results The PanCareSurFup cardiac cohort consisted of 59,915 5-year childhood cancer survivors with malignancies diagnosed between 1940 and 2009 and classified according to the International Classification of Childhood Cancer 3. Different strategies were used to identify cardiac events such as record linkage to population/ hospital or regional based databases, and patient- and general practitioner-based questionnaires. Conclusion The cardiac study of the European collaborative research project PanCareSurFup will provide the largest cohort of 5-year childhood cancer survivors with systematically ascertained and validated data on symptomatic cardiac events. The result of this study can provide information to minimize the burden of cardiac events in childhood cancer survivors by tailoring the follow-up of childhood cancer survivors at high risk of cardiac adverse events, transferring this knowledge into evidence-based clinical practice guidelines and providing a platform for future research studies in childhood cancer patients.  PMID:27643694

  7. Ophthalmic Combination of SurR9-C84A and Trichostatin-A Targeting Molecular Pathogenesis of Alkali Burn

    PubMed Central

    Roy, Kislay; Sriramoju, Bhasker; Kanwar, Rupinder K.; Kanwar, Jagat R.

    2016-01-01

    Background: Alkali burn is a frequently occurring ocular injury that resembles ocular inflammation caused by eye allergies, infection, and refractive surgeries. Methods: We investigated the synergistic regenerative potential of dominant negative survivin mutant (SurR9-C84A) and histone deacetylase (HDAC) inhibitor trichostatin-A (TSA) against alkali burn and corneal haze using human keratocytes and rabbit alkali burn model (Female New Zealand white rabbits). Results: Combination of SurR9-C84A and TSA suppressed levels of transforming growth factor (TGF)-β, alpha smooth-muscle actin (α-SMA), fibronectin and HDAC1, leading to apoptosis in myofibroblast cells and, showed the potential to clear the corneal haze. An insult with 0.5 N NaOH for 1 min led to neutrophils infiltration and formation of large vacuoles in the stroma. Treatments with TSA and SurR9-C84A for 40 min led to improvement in the conjunctival and corneal tissue integrity, marked by an increase in clathrin, and claudin expressions. An increase in TGF-β and endogenous survivin confirmed wound healing and cell proliferation in rabbit cornea. The blood analysis revealed a substantial decrease in the RBC, WBC, platelets, or the hemoglobin content post alkali burn. The cytokine array analysis revealed that NaOH induced expressions of IL-1α and MMP-9, which were found to be significantly downregulated (1.8 and 11.5 fold respectively) by the combinatorial treatment of SurR9-C84A and TSA. Conclusion: Our results confirmed that combination of SurR9-C84A with TSA worked in synergy to heal ocular injury and inflammations due to alkali burn and led to the regeneration of ocular tissue by increasing clathrin, claudin, survivin, and TGF-β and reversal of alkali burn by suppressing IL-1α and MMP-9 without inducing haze. PMID:27516741

  8. The Periplasmic Bacterial Molecular Chaperone SurA Adapts Its Structure to Bind Peptides in Different Conformations to Assert a Sequence Preference for Aromatic Residues

    SciTech Connect

    Xu, X.; Wang, S.; Hu, Y.-X.; McKay, D.B.

    2009-06-04

    The periplasmic molecular chaperone protein SurA facilitates correct folding and maturation of outer membrane proteins in Gram-negative bacteria. It preferentially binds peptides that have a high fraction of aromatic amino acids. Phage display selections, isothermal titration calorimetry and crystallographic structure determination have been used to elucidate the basis of the binding specificity. The peptide recognition is imparted by the first peptidyl-prolyl isomerase (PPIase) domain of SurA. Crystal structures of complexes between peptides of sequence WEYIPNV and NFTLKFWDIFRK with the first PPIase domain of the Escherichia coli SurA protein at 1.3 A resolution, and of a complex between the dodecapeptide and a SurA fragment lacking the second PPIase domain at 3.4 A resolution, have been solved. SurA binds as a monomer to the heptapeptide in an extended conformation. It binds as a dimer to the dodecapeptide in an alpha-helical conformation, predicated on a substantial structural rearrangement of the SurA protein. In both cases, side-chains of aromatic residues of the peptides contribute a large fraction of the binding interactions. SurA therefore asserts a recognition preference for aromatic amino acids in a variety of sequence configurations by adopting alternative tertiary and quaternary structures to bind peptides in different conformations.

  9. Experiential environmental learning: A case study of innovative pedagogy in Baja Sur, Mexico

    NASA Astrophysics Data System (ADS)

    Schneller, Andrew Jon

    This mixed methods case study describes an innovative two-semester middle school environmental learning course that departs from traditional Mexican expository pedagogy through the incorporation of experiential and service learning. This research takes place in a small middle school in Pescadero, Baja California Sur, Mexico. The research approach utilized in the study adds to the handful of studies in this cross-disciplinary field by employing quantitative methodologies to measure course outcomes on student environmental knowledge, perceptions, and actions, while simultaneously qualitatively describing the behavioral, educational, environmental, and social experiences of students. This research employs Dewey's theories of experience---as well as those of more contemporary authenticity theorists---in order to identify the philosophies that advocate incorporating experiential pedagogy within the curriculum. Implications for Mexican educational policy, practical pedagogical applications, and theory are discussed.

  10. Metal concentrations in demersal fish species from Santa Maria Bay, Baja California Sur, Mexico (Pacific coast).

    PubMed

    Jonathan, M P; Aurioles-Gamboa, David; Villegas, Lorena Elizabeth Campos; Bohórquez-Herrera, Jimena; Hernández-Camacho, Claudia J; Sujitha, S B

    2015-10-15

    Concentrations of 11 trace metals (Fe, Mn, Cr, Cu, Ni, Co, Pb, Zn, Cd, As, Hg) in 40 fish species from Santa Maria Bay, Baja California Sur, Mexico, the strategically important area for marine mammals and organisms were analyzed. Based on their concentrations the ranking of metals Fe>Zn>Ni>Cr>Mn>Pb>Cu>Co>As>Cd>Hg suggests that organism size, metabolism and feeding habits are correlated with metal concentrations. Local geological formations affect the concentrations of different metals in the aquatic environment and are subsequently transferred to fishes. The correlation analysis suggests that metabolism and nurturing habits impact the concentration of metals. Concentrations of Fe and Mn appear to be influenced by scavenging and absorption processes, which vary by species. The considerable variability in the metal concentrations obtained in different species underscores the importance of regular monitoring.

  11. Council of Europe Experimental Special Classes for Migrant Workers' Children, Academic Year 1972-73. (Vitry, France).

    ERIC Educational Resources Information Center

    Pestour, Renee; And Others

    During the 1972-73 academic year, an adaptation class for foreign pupils was conducted at the "Anatole France" Co-Educational School in Vitry, France. The class was composed of children between the ages of 6 and 10 years, mainly of Portuguese nationality. Pupils spent 27 hours per week in class. The "Frere Jacques" method, devised by the Office…

  12. Immigrants, Labor Markets, and the State, a Comparative Approach: France and the United States, 1880-1930.

    ERIC Educational Resources Information Center

    Collomp, Catherine

    1999-01-01

    Proposes a comparison of immigration to France and the United States during the period (1880-1930) when industrialization called for a mass working-class migration. Reports that collective immigration in France led to treating foreigners as individuals, while U.S. immigration was understood as an individual act but led to the collective expression…

  13. Sub-Saharan African migrants living with HIV acquired after migration, France, ANRS PARCOURS study, 2012 to 2013.

    PubMed

    Desgrées-du-Loû, Annabel; Pannetier, Julie; Ravalihasy, Andrainolo; Gosselin, Anne; Supervie, Virginie; Panjo, Henri; Bajos, Nathalie; Lert, France; Lydié, Nathalie; Dray-Spira, Rosemary

    2015-01-01

    We estimated the proportion of migrants from sub-Saharan Africa who acquired human immunodeficiency virus (HIV) while living in France. Life-event and clinical information was collected in 2012 and 2013 from a random sample of HIV-infected outpatients born in sub-Saharan Africa and living in the Paris region. We assumed HIV infection in France if at least one of the following was fulfilled: (i) HIV diagnosis at least 11 years after arrival in France, (ii) at least one negative HIV test in France, (iii) sexual debut after arrival in France. Otherwise, time of HIV infection was based on statistical modelling of first CD4(+) T-cell count; infection in France was assumed if more than 50% (median scenario) or more than 95% (conservative scenario) of modelled infection times occurred after migration. We estimated that 49% of 898 HIV-infected adults born in sub-Saharan Africa (95% confidence interval (CI): 45-53) in the median and 35% (95% CI: 31-39) in the conservative scenario acquired HIV while living in France. This proportion was higher in men than women (44% (95% CI: 37-51) vs 30% (95% CI: 25-35); conservative scenario) and increased with length of stay in France. These high proportions highlight the need for improved HIV policies targeting migrants. PMID:26607135

  14. 76 FR 2647 - Ball Bearings and Parts Thereof From France, Germany, Italy, Japan, and the United Kingdom...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-14

    ... International Trade Administration Ball Bearings and Parts Thereof From France, Germany, Italy, Japan, and the...: Effective Date: January 14, 2011. FOR FURTHER INFORMATION CONTACT: Yang Jin Chun, AD/CVD Operations, Office... France, Germany, Italy, Japan, and the United Kingdom for the period May 1, 2009, through April 30,...

  15. 76 FR 58768 - Ball Bearings and Parts Thereof From France, Germany, and Italy; Amended Final Results of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-22

    ... Reviews, 76 FR 52937 (August 24, 2011) (Final Results). The period of review is May 1, 2009, through April... International Trade Administration Ball Bearings and Parts Thereof From France, Germany, and Italy; Amended... ball bearings and parts thereof from France, Germany, and Italy. See Ball Bearings and Parts...

  16. 76 FR 60871 - Ball Bearings and Parts Thereof From France, Germany, and Italy; Termination of Five-Year Reviews

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-30

    ... deadline.'' (76 FR 57019). Accordingly, pursuant to section 751(c) of the Tariff Act of 1930 (19 U.S.C... COMMISSION Ball Bearings and Parts Thereof From France, Germany, and Italy; Termination of Five-Year Reviews... ball bearings and parts thereof from France, Germany, and Italy would be likely to lead to...

  17. 76 FR 35910 - Brass Sheet and Strip From France, Germany, Italy, and Japan; Notice of Commission Determinations...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-20

    ... of institution (76 FR 11509, March 2, 2011) was adequate and that the respondent interested party... COMMISSION Brass Sheet and Strip From France, Germany, Italy, and Japan; Notice of Commission Determinations... from France, Germany, Italy, and Japan AGENCY: United States International Trade Commission....

  18. 76 FR 45853 - Certain Bearings From China, France, Germany, and Italy; Institution of Five-Year Reviews...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-01

    ... bearings from France, Germany, and Italy (54 FR 20900, 20902, and 20903). Following first and second five... China, France, Germany, and Italy (65 FR 42665 and 71 FR 54469). The Commission is now conducting third... amended at 74 FR 2847 (January 16, 2009). \\1\\ No response to this request for information is required if...

  19. La Maison Paternelle: 'A College of Repression' for Wayward Bourgeois Adolescents in Nineteenth and Early Twentieth Century France.

    ERIC Educational Resources Information Center

    Ramsland, John

    1989-01-01

    Describes the Maison Paternelle de St Antoine near Tours, France, which operated as a private institution for the correction of recalcitrant bourgeois adolescents from 1855 until 1909. Cites the suicide of an inmate as the factor which led to the closing of this facility and the focusing of attention in France on the rights of children. (KO)

  20. 78 FR 19311 - Low Enriched Uranium From France; Notice of Commission Determination to Conduct a Full Five-Year...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-29

    ... the domestic interested party group response to its notice of institution (77 FR 71626, December 3... COMMISSION Low Enriched Uranium From France; Notice of Commission Determination to Conduct a Full Five-Year... low enriched uranium from France would be likely to lead to continuation or recurrence of...