Sample records for france palier n4-1450

  1. 7 CFR 1450.4 - Violations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false Violations. 1450.4 Section 1450.4 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Common Provisions...

  2. 7 CFR 1450.4 - Violations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Violations. 1450.4 Section 1450.4 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Common Provisions...

  3. 7 CFR 1450.4 - Violations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Violations. 1450.4 Section 1450.4 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Common Provisions...

  4. 7 CFR 1450.4 - Violations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false Violations. 1450.4 Section 1450.4 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Common Provisions...

  5. 29 CFR 1450.22 - Hearing.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 4 2012-07-01 2012-07-01 false Hearing. 1450.22 Section 1450.22 Labor Regulations Relating... STATES Salary Offset § 1450.22 Hearing. (a) Petition for hearing. (1) A hearing may be requested by..., and is not accepted pursuant to paragraph (a)(4) of this section, the employee's right to hearing will...

  6. 29 CFR 1450.22 - Hearing.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 4 2014-07-01 2014-07-01 false Hearing. 1450.22 Section 1450.22 Labor Regulations Relating... STATES Salary Offset § 1450.22 Hearing. (a) Petition for hearing. (1) A hearing may be requested by..., and is not accepted pursuant to paragraph (a)(4) of this section, the employee's right to hearing will...

  7. 29 CFR 1450.20 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Federal Claims Collection Standards jointly published by the Justice Department and the General Accounting... 29 Labor 4 2010-07-01 2010-07-01 false Definitions. 1450.20 Section 1450.20 Labor Regulations... UNITED STATES Salary Offset § 1450.20 Definitions. For purposes of this subpart— Agency means the Federal...

  8. 29 CFR 1450.6 - Informal action.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 4 2010-07-01 2010-07-01 false Informal action. 1450.6 Section 1450.6 Labor Regulations... UNITED STATES General Provisions § 1450.6 Informal action. Nothing contained in this regulation is intended to preclude utilization of informal administrative actions or remedies which may be available. ...

  9. 29 CFR 1450.23 - Deduction from pay.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 4 2010-07-01 2010-07-01 false Deduction from pay. 1450.23 Section 1450.23 Labor... OWED THE UNITED STATES Salary Offset § 1450.23 Deduction from pay. (a) Deduction by salary offset, from an employee's current disposable pay, shall be subject to the following conditions: (1) Ordinarily...

  10. 29 CFR 1450.16 - Use of consumer reporting agencies.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 4 2011-07-01 2011-07-01 false Use of consumer reporting agencies. 1450.16 Section 1450.16... OF CLAIMS OWED THE UNITED STATES Administrative Offset-Consumer Reporting Agencies-Contracting for Collection § 1450.16 Use of consumer reporting agencies. (a) The term individual means a natural person, and...

  11. 16 CFR 1450.1 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 2 2011-01-01 2011-01-01 false [Reserved] 1450.1 Section 1450.1 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS VIRGINIA GRAEME BAKER POOL AND SPA SAFETY ACT REGULATIONS § 1450.1 [Reserved] ...

  12. 7 CFR 1450.1 - Administration.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false Administration. 1450.1 Section 1450.1 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF... § 1450.1 Administration. (a) The regulations in this part are administered under the general supervision...

  13. 7 CFR 1450.1 - Administration.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false Administration. 1450.1 Section 1450.1 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF... § 1450.1 Administration. (a) The regulations in this part are administered under the general supervision...

  14. 7 CFR 1450.1 - Administration.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Administration. 1450.1 Section 1450.1 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF... § 1450.1 Administration. (a) The regulations in this part are administered under the general supervision...

  15. 21 CFR 870.1450 - Densitometer.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Densitometer. 870.1450 Section 870.1450 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES CARDIOVASCULAR DEVICES Cardiovascular Diagnostic Devices § 870.1450 Densitometer. (a) Identification. A...

  16. 16 CFR 1450.2 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 2 2011-01-01 2011-01-01 false Definitions. 1450.2 Section 1450.2... GRAEME BAKER POOL AND SPA SAFETY ACT REGULATIONS § 1450.2 Definitions. (a) [Reserved] (b) Unblockable... American Society of Mechanical Engineers (ASME), ATTN: Secretary, A112 Standards Committee, Three Park...

  17. 21 CFR 870.1450 - Densitometer.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Densitometer. 870.1450 Section 870.1450 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES CARDIOVASCULAR DEVICES Cardiovascular Diagnostic Devices § 870.1450 Densitometer. (a) Identification. A...

  18. 47 CFR 14.50 - Status conference.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 1 2012-10-01 2012-10-01 false Status conference. 14.50 Section 14.50 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL ACCESS TO ADVANCED COMMUNICATIONS SERVICES AND EQUIPMENT BY PEOPLE WITH DISABILITIES Recordkeeping, Consumer Dispute Assistance, and Enforcement § 14.50...

  19. 29 CFR 1450.16 - Use of consumer reporting agencies.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) Of the specific information to be disclosed to the consumer reporting agency; and (iv) Of the rights... 29 Labor 4 2010-07-01 2010-07-01 false Use of consumer reporting agencies. 1450.16 Section 1450.16... OF CLAIMS OWED THE UNITED STATES Administrative Offset-Consumer Reporting Agencies-Contracting for...

  20. 48 CFR 1450.104 - Residual powers.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Residual powers. 1450.104 Section 1450.104 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Extraordinary Contractual Actions 1450.104 Residual powers. ...

  1. 48 CFR 1450.104 - Residual powers.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Residual powers. 1450.104 Section 1450.104 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Extraordinary Contractual Actions 1450.104 Residual powers. ...

  2. 7 CFR 1450.200 - General.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false General. 1450.200 Section 1450.200 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Establishment...

  3. 7 CFR 1450.200 - General.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false General. 1450.200 Section 1450.200 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Establishment...

  4. 7 CFR 1450.200 - General.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false General. 1450.200 Section 1450.200 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Establishment...

  5. 7 CFR 1450.209 - Signup.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Signup. 1450.209 Section 1450.209 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Establishment...

  6. 7 CFR 1450.200 - General.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false General. 1450.200 Section 1450.200 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Establishment...

  7. 7 CFR 1450.209 - Signup.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Signup. 1450.209 Section 1450.209 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Establishment...

  8. 7 CFR 1450.209 - Signup.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false Signup. 1450.209 Section 1450.209 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Establishment...

  9. 7 CFR 1450.209 - Signup.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false Signup. 1450.209 Section 1450.209 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Establishment...

  10. 7 CFR 1450.9 - Assignments.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Assignments. 1450.9 Section 1450.9 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Common Provisions...

  11. 7 CFR 1450.10 - Appeals.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Appeals. 1450.10 Section 1450.10 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Common Provisions...

  12. 7 CFR 1450.9 - Assignments.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false Assignments. 1450.9 Section 1450.9 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Common Provisions...

  13. 7 CFR 1450.13 - Miscellaneous.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Miscellaneous. 1450.13 Section 1450.13 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Common Provisions...

  14. 7 CFR 1450.10 - Appeals.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false Appeals. 1450.10 Section 1450.10 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Common Provisions...

  15. 7 CFR 1450.13 - Miscellaneous.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Miscellaneous. 1450.13 Section 1450.13 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Common Provisions...

  16. 7 CFR 1450.10 - Appeals.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Appeals. 1450.10 Section 1450.10 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Common Provisions...

  17. 7 CFR 1450.1 - Administration.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Administration. 1450.1 Section 1450.1 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Common Provisions...

  18. 7 CFR 1450.9 - Assignments.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Assignments. 1450.9 Section 1450.9 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Common Provisions...

  19. 7 CFR 1450.10 - Appeals.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false Appeals. 1450.10 Section 1450.10 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Common Provisions...

  20. 7 CFR 1450.13 - Miscellaneous.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false Miscellaneous. 1450.13 Section 1450.13 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Common Provisions...

  1. 7 CFR 1450.13 - Miscellaneous.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false Miscellaneous. 1450.13 Section 1450.13 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Common Provisions...

  2. 7 CFR 1450.9 - Assignments.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false Assignments. 1450.9 Section 1450.9 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Common Provisions...

  3. 7 CFR 1450.205 - Duration of contracts.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Duration of contracts. 1450.205 Section 1450.205...) Establishment Payments and Annual Payments § 1450.205 Duration of contracts. (a) Contracts under this subpart... conditions (for example, establishment time frame, winter hardiness), and other factors. ...

  4. 40 CFR 272.1450-272.1499 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 26 2010-07-01 2010-07-01 false [Reserved] 272.1450-272.1499 Section 272.1450-272.1499 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Nevada §§ 272.1450-272.1499 [Reserved] ...

  5. 21 CFR 890.1450 - Powered reflex hammer.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Powered reflex hammer. 890.1450 Section 890.1450 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES PHYSICAL MEDICINE DEVICES Physical Medicine Diagnostic Devices § 890.1450 Powered reflex...

  6. 21 CFR 890.1450 - Powered reflex hammer.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Powered reflex hammer. 890.1450 Section 890.1450 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES PHYSICAL MEDICINE DEVICES Physical Medicine Diagnostic Devices § 890.1450 Powered reflex...

  7. 21 CFR 890.1450 - Powered reflex hammer.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Powered reflex hammer. 890.1450 Section 890.1450 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES PHYSICAL MEDICINE DEVICES Physical Medicine Diagnostic Devices § 890.1450 Powered reflex...

  8. 21 CFR 890.1450 - Powered reflex hammer.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Powered reflex hammer. 890.1450 Section 890.1450 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES PHYSICAL MEDICINE DEVICES Physical Medicine Diagnostic Devices § 890.1450 Powered reflex...

  9. 21 CFR 890.1450 - Powered reflex hammer.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Powered reflex hammer. 890.1450 Section 890.1450 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES PHYSICAL MEDICINE DEVICES Physical Medicine Diagnostic Devices § 890.1450 Powered reflex...

  10. 7 CFR 1450.11 - Scheme or device.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false Scheme or device. 1450.11 Section 1450.11 Agriculture... § 1450.11 Scheme or device. (a) If CCC determines that a person or legal entity has employed a scheme or...) A scheme or device includes, but is not limited to, coercion, fraud, misrepresentation, depriving...

  11. 7 CFR 1450.11 - Scheme or device.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false Scheme or device. 1450.11 Section 1450.11 Agriculture... § 1450.11 Scheme or device. (a) If CCC determines that a person or legal entity has employed a scheme or...) A scheme or device includes, but is not limited to, coercion, fraud, misrepresentation, depriving...

  12. 7 CFR 1450.11 - Scheme or device.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Scheme or device. 1450.11 Section 1450.11 Agriculture... § 1450.11 Scheme or device. (a) If CCC determines that a person or legal entity has employed a scheme or...) A scheme or device includes, but is not limited to, coercion, fraud, misrepresentation, depriving...

  13. 7 CFR 1450.11 - Scheme or device.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Scheme or device. 1450.11 Section 1450.11 Agriculture... § 1450.11 Scheme or device. (a) If CCC determines that a person or legal entity has employed a scheme or...) A scheme or device includes, but is not limited to, coercion, fraud, misrepresentation, depriving...

  14. 17 CFR 145.0 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 2 2014-04-01 2014-04-01 false Definitions. 145.0 Section 145... RECORDS AND INFORMATION § 145.0 Definitions. For the purposes of part 145 the following definitions are..., microfiche, drawing, or computer-stored information or output in the possession of the Commission. The term...

  15. 17 CFR 145.0 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 1 2012-04-01 2012-04-01 false Definitions. 145.0 Section 145... INFORMATION § 145.0 Definitions. For the purposes of part 145 the following definitions are applicable..., microfiche, drawing, or computer-stored information or output in the possession of the Commission. The term...

  16. 17 CFR 145.0 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Definitions. 145.0 Section 145... INFORMATION § 145.0 Definitions. For the purposes of part 145 the following definitions are applicable..., microfiche, drawing, or computer-stored information or output in the possession of the Commission. The term...

  17. 17 CFR 145.0 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 1 2013-04-01 2013-04-01 false Definitions. 145.0 Section 145... INFORMATION § 145.0 Definitions. For the purposes of part 145 the following definitions are applicable..., microfiche, drawing, or computer-stored information or output in the possession of the Commission. The term...

  18. Formation of Different Si3N4 Nanostructures by Salt-Assisted Nitridation.

    PubMed

    Liu, Xiongzhang; Guo, Ran; Zhang, Sengjing; Li, Qingda; Saito, Genki; Yi, Xuemei; Nomura, Takahiro

    2018-04-11

    Silicon nitride (Si 3 N 4 ) products with different nanostructure morphologies and different phases for Si 3 N 4 ceramic with high thermal conductivity were synthesized by a direct nitriding method. NaCl and NH 4 Cl were added to raw Si powders, and the reaction was carried out under a nitrogen gas flow of 100 mL/min. The phase composition and morphologies of the products were systemically characterized by X-ray diffraction, field emission scanning electron microscopy, and high-resolution transmission electron microscopy. At 1450 °C, the NaCl content was 30 wt %, the NH 4 Cl content was 3 wt %, and the maximum α-Si 3 N 4 content was 96 wt %. The process of Si nitridation can be divided into three stages by analyzing the reaction schemes: in the first stage (25-900 °C), NH 4 Cl decomposition and the generation of stacked amorphous Si 3 N 4 occurs; in the second stage (900-1450 °C), NaCl melts and Si 3 N 4 generates; and in the third stage (>1450 °C), α-Si 3 N 4 → β-Si 3 N 4 phase change and the evaporation of NaCl occurs. The products are made of two layers: a thin upper layer of nanowires containing different nanostructures and a lower layer mainly comprising fluffy, blocky, and short needlelike products. The introduction of NaCl and NH 4 Cl facilitated the evaporation of Si powders and the decomposition of Al 2 O 3 from porcelain boat and furnace tube, which resulted in the mixing of N 2 , O 2 , Al 2 O, and Si vapors and generated Al x Si y O z nanowires with rough surfaces and lead to thin Si 3 N 4 nanowires, nanobranches by the vapor-solid (VS), vapor-liquid-solid (VLS), and the double-stage VLS base and VS tip growth mechanisms.

  19. 7 CFR 1450.212 - Establishment payments.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Establishment payments. 1450.212 Section 1450.212 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP...

  20. 7 CFR 1450.212 - Establishment payments.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false Establishment payments. 1450.212 Section 1450.212 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP...

  1. 7 CFR 1450.212 - Establishment payments.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false Establishment payments. 1450.212 Section 1450.212 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP...

  2. 7 CFR 1450.212 - Establishment payments.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Establishment payments. 1450.212 Section 1450.212 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP...

  3. 33 CFR 80.1450 - Nawiliwili Harbor, Kauai, HI.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Nawiliwili Harbor, Kauai, HI. 80.1450 Section 80.1450 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Pacific Islands § 80.1450 Nawiliwili Harbor, Kauai, HI...

  4. 7 CFR 1450.204 - Eligible land.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Eligible land. 1450.204 Section 1450.204 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Establishment...

  5. 7 CFR 1450.204 - Eligible land.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false Eligible land. 1450.204 Section 1450.204 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Establishment...

  6. 7 CFR 1450.204 - Eligible land.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false Eligible land. 1450.204 Section 1450.204 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Establishment...

  7. 7 CFR 1450.204 - Eligible land.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Eligible land. 1450.204 Section 1450.204 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Establishment...

  8. 48 CFR 1450.102-1 - Delegation of authority.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Delegation of authority. 1450.102-1 Section 1450.102-1 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR... 1450.102-1 Delegation of authority. The AS/PMB shall approve all actions under FAR Part 50, except for...

  9. 48 CFR 1450.101-3 - Records.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Records. 1450.101-3... EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Extraordinary Contractual Actions 1450.101-3 Records. The records of actions taken under FAR Part 50 shall be maintained by the Director, PAM. ...

  10. 48 CFR 1450.101-3 - Records.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Records. 1450.101-3... EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Extraordinary Contractual Actions 1450.101-3 Records. The records of actions taken under FAR Part 50 shall be maintained by the Director, PAM. ...

  11. 48 CFR 1450.101-3 - Records.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Records. 1450.101-3... EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Extraordinary Contractual Actions 1450.101-3 Records. The records of actions taken under FAR Part 50 shall be maintained by the Director, PAM. ...

  12. 48 CFR 1450.101-3 - Records.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Records. 1450.101-3... EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Extraordinary Contractual Actions 1450.101-3 Records. The records of actions taken under FAR Part 50 shall be maintained by the Director, PAM. ...

  13. 21 CFR 862.1450 - Lactic acid test system.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Lactic acid test system. 862.1450 Section 862.1450....1450 Lactic acid test system. (a) Identification. A lactic acid test system is a device intended to measure lactic acid in whole blood and plasma. Lactic acid measurements that evaluate the acid-base status...

  14. 21 CFR 862.1450 - Lactic acid test system.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Lactic acid test system. 862.1450 Section 862.1450....1450 Lactic acid test system. (a) Identification. A lactic acid test system is a device intended to measure lactic acid in whole blood and plasma. Lactic acid measurements that evaluate the acid-base status...

  15. 21 CFR 862.1450 - Lactic acid test system.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Lactic acid test system. 862.1450 Section 862.1450....1450 Lactic acid test system. (a) Identification. A lactic acid test system is a device intended to measure lactic acid in whole blood and plasma. Lactic acid measurements that evaluate the acid-base status...

  16. 21 CFR 862.1450 - Lactic acid test system.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Lactic acid test system. 862.1450 Section 862.1450....1450 Lactic acid test system. (a) Identification. A lactic acid test system is a device intended to measure lactic acid in whole blood and plasma. Lactic acid measurements that evaluate the acid-base status...

  17. 7 CFR 1450.205 - Duration of contracts.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false Duration of contracts. 1450.205 Section 1450.205 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP...

  18. 7 CFR 1450.105 - Obligations of participant.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false Obligations of participant. 1450.105 Section 1450.105 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Matching...

  19. 7 CFR 1450.215 - Transfer of land.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Transfer of land. 1450.215 Section 1450.215 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP...

  20. 7 CFR 1450.105 - Obligations of participant.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Obligations of participant. 1450.105 Section 1450.105 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Matching...

  1. 7 CFR 1450.105 - Obligations of participant.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Obligations of participant. 1450.105 Section 1450.105 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Matching...

  2. 7 CFR 1450.205 - Duration of contracts.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Duration of contracts. 1450.205 Section 1450.205 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP...

  3. 7 CFR 1450.215 - Transfer of land.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false Transfer of land. 1450.215 Section 1450.215 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP...

  4. 7 CFR 1450.105 - Obligations of participant.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false Obligations of participant. 1450.105 Section 1450.105 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Matching...

  5. 7 CFR 1450.210 - Acceptability of offers.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Acceptability of offers. 1450.210 Section 1450.210 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP...

  6. 7 CFR 1450.210 - Acceptability of offers.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false Acceptability of offers. 1450.210 Section 1450.210 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP...

  7. 7 CFR 1450.210 - Acceptability of offers.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false Acceptability of offers. 1450.210 Section 1450.210 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP...

  8. 7 CFR 1450.205 - Duration of contracts.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false Duration of contracts. 1450.205 Section 1450.205 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP...

  9. 7 CFR 1450.215 - Transfer of land.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false Transfer of land. 1450.215 Section 1450.215 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP...

  10. 7 CFR 1450.215 - Transfer of land.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Transfer of land. 1450.215 Section 1450.215 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP...

  11. 7 CFR 1450.210 - Acceptability of offers.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Acceptability of offers. 1450.210 Section 1450.210 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP...

  12. 7 CFR 1450.6 - Access to land.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false Access to land. 1450.6 Section 1450.6 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Common Provisions...

  13. 7 CFR 1450.6 - Access to land.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Access to land. 1450.6 Section 1450.6 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Common Provisions...

  14. 7 CFR 1450.6 - Access to land.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false Access to land. 1450.6 Section 1450.6 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Common Provisions...

  15. 7 CFR 1450.6 - Access to land.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Access to land. 1450.6 Section 1450.6 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Common Provisions...

  16. 14 CFR 25.1450 - Chemical oxygen generators.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Chemical oxygen generators. 25.1450 Section... AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY AIRPLANES Equipment Miscellaneous Equipment § 25.1450 Chemical oxygen generators. (a) For the purpose of this section, a chemical oxygen generator is defined as a...

  17. 14 CFR 25.1450 - Chemical oxygen generators.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Chemical oxygen generators. 25.1450 Section... AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY AIRPLANES Equipment Miscellaneous Equipment § 25.1450 Chemical oxygen generators. (a) For the purpose of this section, a chemical oxygen generator is defined as a...

  18. 14 CFR 23.1450 - Chemical oxygen generators.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Chemical oxygen generators. 23.1450 Section... Equipment § 23.1450 Chemical oxygen generators. (a) For the purpose of this section, a chemical oxygen generator is defined as a device which produces oxygen by chemical reaction. (b) Each chemical oxygen...

  19. 14 CFR 23.1450 - Chemical oxygen generators.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Chemical oxygen generators. 23.1450 Section... Equipment § 23.1450 Chemical oxygen generators. (a) For the purpose of this section, a chemical oxygen generator is defined as a device which produces oxygen by chemical reaction. (b) Each chemical oxygen...

  20. 14 CFR 23.1450 - Chemical oxygen generators.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Chemical oxygen generators. 23.1450 Section... Equipment § 23.1450 Chemical oxygen generators. (a) For the purpose of this section, a chemical oxygen generator is defined as a device which produces oxygen by chemical reaction. (b) Each chemical oxygen...

  1. 14 CFR 23.1450 - Chemical oxygen generators.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Chemical oxygen generators. 23.1450 Section... Equipment § 23.1450 Chemical oxygen generators. (a) For the purpose of this section, a chemical oxygen generator is defined as a device which produces oxygen by chemical reaction. (b) Each chemical oxygen...

  2. 14 CFR 23.1450 - Chemical oxygen generators.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Chemical oxygen generators. 23.1450 Section... Equipment § 23.1450 Chemical oxygen generators. (a) For the purpose of this section, a chemical oxygen generator is defined as a device which produces oxygen by chemical reaction. (b) Each chemical oxygen...

  3. 7 CFR 1450.12 - Filing of false claims.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false Filing of false claims. 1450.12 Section 1450.12 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Common...

  4. 7 CFR 1450.101 - Qualified biomass conversion facility.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false Qualified biomass conversion facility. 1450.101... CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Matching Payments § 1450.101 Qualified biomass conversion facility. (a) To be considered a...

  5. 7 CFR 1450.12 - Filing of false claims.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Filing of false claims. 1450.12 Section 1450.12 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Common...

  6. 7 CFR 1450.101 - Qualified biomass conversion facility.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Qualified biomass conversion facility. 1450.101... CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Matching Payments § 1450.101 Qualified biomass conversion facility. (a) To be considered a...

  7. 7 CFR 1450.12 - Filing of false claims.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Filing of false claims. 1450.12 Section 1450.12 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Common...

  8. 7 CFR 1450.101 - Qualified biomass conversion facility.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false Qualified biomass conversion facility. 1450.101... CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Matching Payments § 1450.101 Qualified biomass conversion facility. (a) To be considered a...

  9. 7 CFR 1450.12 - Filing of false claims.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false Filing of false claims. 1450.12 Section 1450.12 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Common...

  10. 7 CFR 1450.101 - Qualified biomass conversion facility.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Qualified biomass conversion facility. 1450.101... (BCAP) Matching Payments § 1450.101 Qualified biomass conversion facility. (a) To be considered a qualified biomass conversion facility, a biomass conversion facility must enter into an agreement with CCC...

  11. 21 CFR 886.1450 - Corneal radius measuring device.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Corneal radius measuring device. 886.1450 Section... (CONTINUED) MEDICAL DEVICES OPHTHALMIC DEVICES Diagnostic Devices § 886.1450 Corneal radius measuring device. (a) Identification. A corneal radius measuring device is an AC-powered device intended to measure...

  12. 21 CFR 862.1450 - Lactic acid test system.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Lactic acid test system. 862.1450 Section 862.1450 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES CLINICAL CHEMISTRY AND CLINICAL TOXICOLOGY DEVICES Clinical Chemistry Test Systems § 862...

  13. 18 CFR 367.1450 - Account 145, Notes receivable from associate companies.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... POWER ACT AND NATURAL GAS ACT Balance Sheet Chart of Accounts Current and Accrued Assets § 367.1450... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Account 145, Notes receivable from associate companies. 367.1450 Section 367.1450 Conservation of Power and Water Resources...

  14. Non-ablative 1,450-nm diode laser treatment of striae distensae.

    PubMed

    Tay, Yong-Kwang; Kwok, Colin; Tan, Eileen

    2006-03-01

    Striae distensae are dermal scars with flattening and atrophy of the epidermis. Successful treatment of these stretch marks has been disappointing. The non-ablative 1,450-nm diode laser has been shown to improve atrophic scars and may be expected to improve striae. As yet, no study has been published to document the effects of this laser on striae. Our aim is to evaluate the efficacy of the 1,450-nm diode laser in the treatment of striae rubra and striae alba in Asian patients with skin types 4-6. Striae on one half of the body in 11 patients were treated with the 1,450-nm diode laser with cryogen cooling spray with the other half serving as a control. The following parameters were used: 6 mm spot size and dynamic cooling device (DCD) for 40 milliseconds to protect the epidermis. Patients were randomly assigned to receive either 4, 8, or 12 J/cm2. A total of three treatments were given at 6-week intervals. The following sites were treated: abdomen, arms, back, buttocks, and thighs. Two patients had striae rubra and nine striae alba. Clinical photographs were taken before and after each treatment and analysis was undertaken through photographic evaluation by non-treating physicians. At 2 months after the last treatment, no patients showed any noticeable improvement in the striae on the treated side compared to baseline and to the control areas. Side effects were limited to transient erythema and postinflammatory hyperpigmentation (PIH), which occurred in seven (64%) patients. The non-ablative 1,450-nm diode laser is not useful in the treatment of striae in patients with skin types 4, 5, and 6. 2006 Wiley-Liss, Inc.

  15. 42 CFR § 414.1450 - APM incentive payment.

    Code of Federal Regulations, 2010 CFR

    2017-10-01

    ... (CONTINUED) MEDICARE PROGRAM (CONTINUED) PAYMENT FOR PART B MEDICAL AND OTHER HEALTH SERVICES Merit-Based Incentive Payment System and Alternative Payment Model Incentive § 414.1450 APM incentive payment. (a) In... 42 Public Health 3 2017-10-01 2017-10-01 false APM incentive payment. § 414.1450 Section § 414...

  16. 13 CFR 107.1450 - Optional redemption of Preferred Securities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Optional redemption of Preferred Securities. 107.1450 Section 107.1450 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION SMALL BUSINESS INVESTMENT COMPANIES SBA Financial Assistance for Licensees (Leverage) Preferred Securities...

  17. 7 CFR 1450.203 - Eligible persons and legal entities.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false Eligible persons and legal entities. 1450.203 Section 1450.203 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM...

  18. 7 CFR 1450.203 - Eligible persons and legal entities.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Eligible persons and legal entities. 1450.203 Section 1450.203 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM...

  19. 7 CFR 1450.203 - Eligible persons and legal entities.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Eligible persons and legal entities. 1450.203 Section 1450.203 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM...

  20. 7 CFR 1450.203 - Eligible persons and legal entities.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false Eligible persons and legal entities. 1450.203 Section 1450.203 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM...

  1. 7 CFR 1450.8 - Payments not subject to claims.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false Payments not subject to claims. 1450.8 Section 1450.8 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Common...

  2. 7 CFR 1450.8 - Payments not subject to claims.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false Payments not subject to claims. 1450.8 Section 1450.8 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Common...

  3. 7 CFR 1450.8 - Payments not subject to claims.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Payments not subject to claims. 1450.8 Section 1450.8 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Common...

  4. 7 CFR 1450.8 - Payments not subject to claims.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Payments not subject to claims. 1450.8 Section 1450.8 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Common...

  5. 48 CFR 1450.102 - Delegation of and limitations on exercise of authority.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Delegation of and limitations on exercise of authority. 1450.102 Section 1450.102 Federal Acquisition Regulations System... Extraordinary Contractual Actions 1450.102 Delegation of and limitations on exercise of authority. ...

  6. 48 CFR 1450.102 - Delegation of and limitations on exercise of authority.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Delegation of and limitations on exercise of authority. 1450.102 Section 1450.102 Federal Acquisition Regulations System... Extraordinary Contractual Actions 1450.102 Delegation of and limitations on exercise of authority. ...

  7. 48 CFR 1450.102 - Delegation of and limitations on exercise of authority.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Delegation of and limitations on exercise of authority. 1450.102 Section 1450.102 Federal Acquisition Regulations System... Extraordinary Contractual Actions 1450.102 Delegation of and limitations on exercise of authority. ...

  8. 48 CFR 1450.102 - Delegation of and limitations on exercise of authority.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Delegation of and limitations on exercise of authority. 1450.102 Section 1450.102 Federal Acquisition Regulations System... Extraordinary Contractual Actions 1450.102 Delegation of and limitations on exercise of authority. ...

  9. 48 CFR 1450.102 - Delegation of and limitations on exercise of authority.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Delegation of and limitations on exercise of authority. 1450.102 Section 1450.102 Federal Acquisition Regulations System... Extraordinary Contractual Actions 1450.102 Delegation of and limitations on exercise of authority. ...

  10. 7 CFR 1450.213 - Levels and rates for establishment payments.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false Levels and rates for establishment payments. 1450.213 Section 1450.213 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM...

  11. 7 CFR 1450.213 - Levels and rates for establishment payments.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false Levels and rates for establishment payments. 1450.213 Section 1450.213 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM...

  12. 48 CFR 1450.104-3 - Special procedures for unusually hazardous or nuclear risks.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Special procedures for unusually hazardous or nuclear risks. 1450.104-3 Section 1450.104-3 Federal Acquisition Regulations System... Extraordinary Contractual Actions 1450.104-3 Special procedures for unusually hazardous or nuclear risks. The CO...

  13. 48 CFR 1450.104-3 - Special procedures for unusually hazardous or nuclear risks.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Special procedures for unusually hazardous or nuclear risks. 1450.104-3 Section 1450.104-3 Federal Acquisition Regulations System... Extraordinary Contractual Actions 1450.104-3 Special procedures for unusually hazardous or nuclear risks. The CO...

  14. 48 CFR 1450.104-3 - Special procedures for unusually hazardous or nuclear risks.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Special procedures for unusually hazardous or nuclear risks. 1450.104-3 Section 1450.104-3 Federal Acquisition Regulations System... Extraordinary Contractual Actions 1450.104-3 Special procedures for unusually hazardous or nuclear risks. The CO...

  15. 48 CFR 1450.104-3 - Special procedures for unusually hazardous or nuclear risks.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Special procedures for unusually hazardous or nuclear risks. 1450.104-3 Section 1450.104-3 Federal Acquisition Regulations System... Extraordinary Contractual Actions 1450.104-3 Special procedures for unusually hazardous or nuclear risks. The CO...

  16. 12 CFR 14.50 - Where insurance activities may take place.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ....50 Section 14.50 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY CONSUMER PROTECTION IN SALES OF INSURANCE § 14.50 Where insurance activities may take place. (a) General rule. A bank... transactions are routinely conducted in the bank may refer a consumer who seeks to purchase an insurance...

  17. 7 CFR 1450.3 - General.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Common Provisions § 1450.3 General. (a) The objectives of BCAP are to: (1) Support the establishment and production of..., storage, and transportation costs of eligible material for use in a biomass conversion facility. (b) A...

  18. 7 CFR 1450.3 - General.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Common Provisions § 1450.3 General. (a) The objectives of BCAP are to: (1) Support the establishment and production of..., storage, and transportation costs of eligible material for use in a biomass conversion facility. (b) A...

  19. 7 CFR 1450.3 - General.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Common Provisions § 1450.3 General. (a) The objectives of BCAP are to: (1) Support the establishment and production of..., storage, and transportation costs of eligible material for use in a biomass conversion facility. (b) A...

  20. 7 CFR 1450.3 - General.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Common Provisions § 1450.3 General. (a) The objectives of BCAP are to: (1) Support the establishment and production of..., storage, and transportation costs of eligible material for use in a biomass conversion facility. (b) A...

  1. Retrospective Analysis of NIST Standard Reference Material 1450, Fibrous Glass Board, for Thermal Insulation Measurements

    PubMed Central

    Zarr, Robert R; Heckert, N Alan; Leigh, Stefan D

    2014-01-01

    Thermal conductivity data acquired previously for the establishment of Standard Reference Material (SRM) 1450, Fibrous Glass Board, as well as subsequent renewals 1450a, 1450b, 1450c, and 1450d, are re-analyzed collectively and as individual data sets. Additional data sets for proto-1450 material lots are also included in the analysis. The data cover 36 years of activity by the National Institute of Standards and Technology (NIST) in developing and providing thermal insulation SRMs, specifically high-density molded fibrous-glass board, to the public. Collectively, the data sets cover two nominal thicknesses of 13 mm and 25 mm, bulk densities from 60 kg·m−3 to 180 kg·m−3, and mean temperatures from 100 K to 340 K. The analysis repetitively fits six models to the individual data sets. The most general form of the nested set of multilinear models used is given in the following equation: λ(ρ,T)=a0+a1ρ+a2T+a3T3+a4e−(T−a5a6)2where λ(ρ,T) is the predicted thermal conductivity (W·m−1·K−1), ρ is the bulk density (kg·m−3), T is the mean temperature (K) and ai (for i = 1, 2, … 6) are the regression coefficients. The least squares fit results for each model across all data sets are analyzed using both graphical and analytic techniques. The prevailing generic model for the majority of data sets is the bilinear model in ρ and T. λ(ρ,T)=a0+a1ρ+a2T One data set supports the inclusion of a cubic temperature term and two data sets with low-temperature data support the inclusion of an exponential term in T to improve the model predictions. Physical interpretations of the model function terms are described. Recommendations for future renewals of SRM 1450 are provided. An Addendum provides historical background on the origin of this SRM and the influence of the SRM on external measurement programs. PMID:26601034

  2. 17 CFR 145.0 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... INFORMATION § 145.0 Definitions. For the purposes of part 145 the following definitions are applicable: Assistant Secretary—refers to the Assistant Secretary of the Commission for FOI, Privacy and Sunshine Acts Compliance. Compliance staff—refers to the FOI, Privacy and Sunshine Acts Compliance staff of the Office of...

  3. 29 CFR 1915.1450 - Occupational exposure to hazardous chemicals in laboratories.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 7 2010-07-01 2010-07-01 false Occupational exposure to hazardous chemicals in laboratories. 1915.1450 Section 1915.1450 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY... chemicals in laboratories. Note: The requirements applicable to shipyard employment under this section are...

  4. 29 CFR 1915.1450 - Occupational exposure to hazardous chemicals in laboratories.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 7 2014-07-01 2014-07-01 false Occupational exposure to hazardous chemicals in laboratories. 1915.1450 Section 1915.1450 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY... chemicals in laboratories. Note: The requirements applicable to shipyard employment under this section are...

  5. 29 CFR 1910.1450 - Occupational exposure to hazardous chemicals in laboratories.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 6 2010-07-01 2010-07-01 false Occupational exposure to hazardous chemicals in laboratories. 1910.1450 Section 1910.1450 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) OCCUPATIONAL SAFETY AND HEALTH STANDARDS (CONTINUED) Toxic and Hazardous Substances §...

  6. 29 CFR 1910.1450 - Occupational exposure to hazardous chemicals in laboratories.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 6 2013-07-01 2013-07-01 false Occupational exposure to hazardous chemicals in laboratories. 1910.1450 Section 1910.1450 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) OCCUPATIONAL SAFETY AND HEALTH STANDARDS (CONTINUED) Toxic and Hazardous Substances §...

  7. 29 CFR 1910.1450 - Occupational exposure to hazardous chemicals in laboratories.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 6 2014-07-01 2013-07-01 true Occupational exposure to hazardous chemicals in laboratories. 1910.1450 Section 1910.1450 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) OCCUPATIONAL SAFETY AND HEALTH STANDARDS (CONTINUED) Toxic and Hazardous Substances §...

  8. THE CANADA-FRANCE HIGH-z QUASAR SURVEY: NINE NEW QUASARS AND THE LUMINOSITY FUNCTION AT REDSHIFT 6

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Willott, Chris J.; Crampton, David; Hutchings, John B.

    2010-03-15

    We present discovery imaging and spectroscopy for nine new z {approx} 6 quasars found in the Canada-France High-z Quasar Survey (CFHQS) bringing the total number of CFHQS quasars to 19. By combining the CFHQS with the more luminous Sloan Digital Sky Survey sample, we are able to derive the quasar luminosity function from a sample of 40 quasars at redshifts 5.74 < z < 6.42. Our binned luminosity function shows a slightly lower normalization and flatter slope than found in previous work. The binned data also suggest a break in the luminosity function at M {sub 1450} {approx} -25. Amore » double power-law maximum likelihood fit to the data is consistent with the binned results. The luminosity function is strongly constrained (1{sigma} uncertainty <0.1 dex) over the range -27.5 < M {sub 1450} < -24.7. The best-fit parameters are {phi}(M*{sub 1450}) = 1.14 x 10{sup -8} Mpc{sup -3} mag{sup -1}, break magnitude M*{sub 1450} = -25.13, and bright end slope {beta} = -2.81. However, the covariance between {beta} and M*{sub 1450} prevents strong constraints being placed on either parameter. For a break magnitude in the range -26 < M*{sub 1450} < -24, we find -3.8 < {beta} < -2.3 at 95% confidence. We calculate the z = 6 quasar intergalactic ionizing flux and show it is between 20 and 100 times lower than that necessary for reionization. Finally, we use the luminosity function to predict how many higher redshift quasars may be discovered in future near-IR imaging surveys.« less

  9. New Introductions of Enterovirus 71 Subgenogroup C4 Strains, France, 2012

    PubMed Central

    Henquell, Cécile; Mirand, Audrey; Coste-Burel, Marianne; Marque-Juillet, Stéphanie; Desbois, Delphine; Lagathu, Gisèle; Bornebusch, Laure; Bailly, Jean-Luc; Lina, Bruno

    2014-01-01

    In France during 2012, human enterovirus 71 (EV-A71) subgenogroup C4 strains were detected in 4 children hospitalized for neonatal fever or meningitis. Phylogenetic analysis showed novel and independent EV-A71 introductions, presumably from China, and suggested circulation of C4 strains throughout France. This observation emphasizes the need for monitoring EV-A71 infections in Europe. PMID:25061698

  10. 7 CFR 1450.7 - Division of payments and provisions about tenants and sharecroppers.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false Division of payments and provisions about tenants and sharecroppers. 1450.7 Section 1450.7 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP...

  11. 7 CFR 1450.7 - Division of payments and provisions about tenants and sharecroppers.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false Division of payments and provisions about tenants and sharecroppers. 1450.7 Section 1450.7 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP...

  12. 7 CFR 1450.7 - Division of payments and provisions about tenants and sharecroppers.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Division of payments and provisions about tenants and sharecroppers. 1450.7 Section 1450.7 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP...

  13. 7 CFR 1450.7 - Division of payments and provisions about tenants and sharecroppers.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Division of payments and provisions about tenants and sharecroppers. 1450.7 Section 1450.7 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP...

  14. 7 CFR 1450.5 - Performance based on advice or action of USDA.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Performance based on advice or action of USDA. 1450.5... (BCAP) Common Provisions § 1450.5 Performance based on advice or action of USDA. (a) The provisions of... representative of USDA apply to this part, and may be considered as a basis to provide relief to persons subject...

  15. 7 CFR 1450.5 - Performance based on advice or action of USDA.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false Performance based on advice or action of USDA. 1450.5... (BCAP) Common Provisions § 1450.5 Performance based on advice or action of USDA. (a) The provisions of... representative of USDA apply to this part, and may be considered as a basis to provide relief to persons subject...

  16. 7 CFR 1450.5 - Performance based on advice or action of USDA.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Performance based on advice or action of USDA. 1450.5... (BCAP) Common Provisions § 1450.5 Performance based on advice or action of USDA. (a) The provisions of... representative of USDA applies to this part, and may be considered as a basis to provide relief to persons...

  17. 7 CFR 1450.5 - Performance based on advice or action of USDA.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false Performance based on advice or action of USDA. 1450.5... (BCAP) Common Provisions § 1450.5 Performance based on advice or action of USDA. (a) The provisions of... representative of USDA apply to this part, and may be considered as a basis to provide relief to persons subject...

  18. 14 CFR 25.1450 - Chemical oxygen generators.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Chemical oxygen generators. 25.1450 Section... oxygen generators. (a) For the purpose of this section, a chemical oxygen generator is defined as a device which produces oxygen by chemical reaction. (b) Each chemical oxygen generator must be designed...

  19. 14 CFR 25.1450 - Chemical oxygen generators.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Chemical oxygen generators. 25.1450 Section... oxygen generators. (a) For the purpose of this section, a chemical oxygen generator is defined as a device which produces oxygen by chemical reaction. (b) Each chemical oxygen generator must be designed...

  20. 14 CFR 25.1450 - Chemical oxygen generators.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Chemical oxygen generators. 25.1450 Section... oxygen generators. (a) For the purpose of this section, a chemical oxygen generator is defined as a device which produces oxygen by chemical reaction. (b) Each chemical oxygen generator must be designed...

  1. Retrospective Analysis of NIST Standard Reference Material 1450, Fibrous Glass Board, for Thermal Insulation Measurements.

    PubMed

    Zarr, Robert R; Heckert, N Alan; Leigh, Stefan D

    2014-01-01

    Thermal conductivity data acquired previously for the establishment of Standard Reference Material (SRM) 1450, Fibrous Glass Board, as well as subsequent renewals 1450a, 1450b, 1450c, and 1450d, are re-analyzed collectively and as individual data sets. Additional data sets for proto-1450 material lots are also included in the analysis. The data cover 36 years of activity by the National Institute of Standards and Technology (NIST) in developing and providing thermal insulation SRMs, specifically high-density molded fibrous-glass board, to the public. Collectively, the data sets cover two nominal thicknesses of 13 mm and 25 mm, bulk densities from 60 kg·m(-3) to 180 kg·m(-3), and mean temperatures from 100 K to 340 K. The analysis repetitively fits six models to the individual data sets. The most general form of the nested set of multilinear models used is given in the following equation: [Formula: see text]where λ(ρ,T) is the predicted thermal conductivity (W·m(-1)·K(-1)), ρ is the bulk density (kg·m(-3)), T is the mean temperature (K) and ai (for i = 1, 2, … 6) are the regression coefficients. The least squares fit results for each model across all data sets are analyzed using both graphical and analytic techniques. The prevailing generic model for the majority of data sets is the bilinear model in ρ and T. [Formula: see text] One data set supports the inclusion of a cubic temperature term and two data sets with low-temperature data support the inclusion of an exponential term in T to improve the model predictions. Physical interpretations of the model function terms are described. Recommendations for future renewals of SRM 1450 are provided. An Addendum provides historical background on the origin of this SRM and the influence of the SRM on external measurement programs.

  2. 40 CFR 60.1450 - How must I monitor opacity for air curtain incinerators that burn 100 percent yard waste?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... curtain incinerators that burn 100 percent yard waste? 60.1450 Section 60.1450 Protection of Environment... Air Curtain Incinerators That Burn 100 Percent Yard Waste § 60.1450 How must I monitor opacity for air curtain incinerators that burn 100 percent yard waste? (a) Use EPA Reference Method 9 in appendix A of...

  3. 40 CFR 60.1450 - How must I monitor opacity for air curtain incinerators that burn 100 percent yard waste?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... curtain incinerators that burn 100 percent yard waste? 60.1450 Section 60.1450 Protection of Environment... Air Curtain Incinerators That Burn 100 Percent Yard Waste § 60.1450 How must I monitor opacity for air curtain incinerators that burn 100 percent yard waste? (a) Use EPA Reference Method 9 in appendix A of...

  4. 40 CFR 60.1450 - How must I monitor opacity for air curtain incinerators that burn 100 percent yard waste?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... curtain incinerators that burn 100 percent yard waste? 60.1450 Section 60.1450 Protection of Environment... Air Curtain Incinerators That Burn 100 Percent Yard Waste § 60.1450 How must I monitor opacity for air curtain incinerators that burn 100 percent yard waste? (a) Use EPA Reference Method 9 in appendix A of...

  5. 40 CFR 60.1450 - How must I monitor opacity for air curtain incinerators that burn 100 percent yard waste?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... curtain incinerators that burn 100 percent yard waste? 60.1450 Section 60.1450 Protection of Environment... Air Curtain Incinerators That Burn 100 Percent Yard Waste § 60.1450 How must I monitor opacity for air curtain incinerators that burn 100 percent yard waste? (a) Use EPA Reference Method 9 in appendix A of...

  6. 40 CFR 60.1450 - How must I monitor opacity for air curtain incinerators that burn 100 percent yard waste?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... curtain incinerators that burn 100 percent yard waste? 60.1450 Section 60.1450 Protection of Environment... Air Curtain Incinerators That Burn 100 Percent Yard Waste § 60.1450 How must I monitor opacity for air curtain incinerators that burn 100 percent yard waste? (a) Use EPA Reference Method 9 in appendix A of...

  7. Treatment of inflammatory facial acne vulgaris in Chinese patients with the 1450-nm diode laser: a pilot study

    NASA Astrophysics Data System (ADS)

    Liu, Huaxu; Dang, Yongyan; Wang, Zhan; Ma, Li; Ren, Qiushi

    2007-02-01

    The 1450-nm diode laser has been found to be effective for the treatment of inflammatory acne in USA, Europe and Japan. However, there is no report on its efficacy in Chinese acne vulgaris patients. We conduct this pilot study to evaluate the efficacy and safety of the 1450-nm diode laser in the treatment of inflammatory facial acne vulgaris in Chinese patients. Nineteen patients with inflammatory facial acne were treated with the 1450-nm diode laser at 4- to 6-week intervals. Clinical photographs and lesion counts were obtained at baseline and after each treatment. Subjective evaluation of response to treatment and pain was assessed using a questionnaire. In our study, clinical improvement was seen in all patients and was generally dramatic. Lesion counts decreased 34% after one treatment (p<0.01), 56% after two treatments (p<0.01), and 81% after three treatments (p<0.01). However, the treatment-related pain was comparatively hard to be tolerated in Chinese patitents, and the other main adverse effect was the hyper-pigmentation after treatments (36.84%, 7/19).

  8. Effect of a third application of toothpastes (1450 and 5000 ppm F), including a 'massage' method on fluoride retention and pH drop in plaque.

    PubMed

    Nordström, Anna; Birkhed, Dowen

    2013-01-01

    The aim was to investigate fluoride (F) retention in plaque, saliva and pH drop in plaque using high-F toothpaste (5000 ppm F) or standard toothpaste (1450 ppm F) twice a day or 3-times a day. A method using the toothpaste as a 'lotion' and massaging the buccal surfaces with the fingertip was also evaluated. The investigation had a randomized, single-blinded, cross-over design and 16 subjects participated in six brushing regimes: (1) 5000 ppm F; twice a day, (2) 5000 ppm; 3-times/day, (3) 5000 ppm; twice a day, plus the 'massage' method once a day, (4) 1450 ppm F; twice a day, (5) 1450 ppm; 3-times/day and (6) 1450 ppm; twice a day, plus the 'massage' method once a day. The outcome measure was F retention in plaque, saliva and the plaque-pH change after a sucrose rinse. The highest F concentration was found using high-F toothpaste (No 1-3) and differed significantly from those with 1450 ppm (No 4-6). Brushing with high-F toothpaste 3-times a day (No 2) resulted in a 3.6-times higher F saliva value compared with standard toothpaste twice a day (No 4) (p < 0.001). Increasing the frequency of application, from twice to 3-times a day, increased the F retention in plaque significantly when the two methods for application 3-times a day were pooled (p < 0.05). Brushing with 5000 and 1450 ppm toothpastes twice a day plus the 'massage' once a day resulted in the same F concentration in saliva and plaque as brushing 3-times a day with the same paste. A third application of toothpaste is increasing the F retention and toothpaste as a 'lotion' and massaging the buccal surfaces with the fingertip may be a simple and inexpensive way of delivering F a third time during the day.

  9. 33 CFR 334.1450 - Atlantic Ocean off north coast of Puerto Rico; practice firing areas, U.S. Army Forces Antilles.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 3 2012-07-01 2012-07-01 false Atlantic Ocean off north coast of Puerto Rico; practice firing areas, U.S. Army Forces Antilles. 334.1450 Section 334.1450 Navigation and... RESTRICTED AREA REGULATIONS § 334.1450 Atlantic Ocean off north coast of Puerto Rico; practice firing areas...

  10. 33 CFR 334.1450 - Atlantic Ocean off north coast of Puerto Rico; practice firing areas, U.S. Army Forces Antilles.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 3 2014-07-01 2014-07-01 false Atlantic Ocean off north coast of Puerto Rico; practice firing areas, U.S. Army Forces Antilles. 334.1450 Section 334.1450 Navigation and... RESTRICTED AREA REGULATIONS § 334.1450 Atlantic Ocean off north coast of Puerto Rico; practice firing areas...

  11. 33 CFR 334.1450 - Atlantic Ocean off north coast of Puerto Rico; practice firing areas, U.S. Army Forces Antilles.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 3 2013-07-01 2013-07-01 false Atlantic Ocean off north coast of Puerto Rico; practice firing areas, U.S. Army Forces Antilles. 334.1450 Section 334.1450 Navigation and... RESTRICTED AREA REGULATIONS § 334.1450 Atlantic Ocean off north coast of Puerto Rico; practice firing areas...

  12. 33 CFR 334.1450 - Atlantic Ocean off north coast of Puerto Rico; practice firing areas, U.S. Army Forces Antilles.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 3 2011-07-01 2011-07-01 false Atlantic Ocean off north coast of Puerto Rico; practice firing areas, U.S. Army Forces Antilles. 334.1450 Section 334.1450 Navigation and... RESTRICTED AREA REGULATIONS § 334.1450 Atlantic Ocean off north coast of Puerto Rico; practice firing areas...

  13. Temporal Trends in Transcatheter Aortic Valve Replacement in France: FRANCE 2 to FRANCE TAVI.

    PubMed

    Auffret, Vincent; Lefevre, Thierry; Van Belle, Eric; Eltchaninoff, Hélène; Iung, Bernard; Koning, René; Motreff, Pascal; Leprince, Pascal; Verhoye, Jean Philippe; Manigold, Thibaut; Souteyrand, Geraud; Boulmier, Dominique; Joly, Patrick; Pinaud, Frédéric; Himbert, Dominique; Collet, Jean Philippe; Rioufol, Gilles; Ghostine, Said; Bar, Olivier; Dibie, Alain; Champagnac, Didier; Leroux, Lionel; Collet, Frédéric; Teiger, Emmanuel; Darremont, Olivier; Folliguet, Thierry; Leclercq, Florence; Lhermusier, Thibault; Olhmann, Patrick; Huret, Bruno; Lorgis, Luc; Drogoul, Laurent; Bertrand, Bernard; Spaulding, Christian; Quilliet, Laurent; Cuisset, Thomas; Delomez, Maxence; Beygui, Farzin; Claudel, Jean-Philippe; Hepp, Alain; Jegou, Arnaud; Gommeaux, Antoine; Mirode, Anfani; Christiaens, Luc; Christophe, Charles; Cassat, Claude; Metz, Damien; Mangin, Lionel; Isaaz, Karl; Jacquemin, Laurent; Guyon, Philippe; Pouillot, Christophe; Makowski, Serge; Bataille, Vincent; Rodés-Cabau, Josep; Gilard, Martine; Le Breton, Hervé

    2017-07-04

    Transcatheter aortic valve replacement (TAVR) is standard therapy for patients with severe aortic stenosis who are at high surgical risk. However, national data regarding procedural characteristics and clinical outcomes over time are limited. The aim of this study was to assess nationwide performance trends and clinical outcomes of TAVR during a 6-year period. TAVRs performed in 48 centers across France between January 2013 and December 2015 were prospectively included in the FRANCE TAVI (French Transcatheter Aortic Valve Implantation) registry. Findings were further compared with those reported from the FRANCE 2 (French Aortic National CoreValve and Edwards 2) registry, which captured all TAVRs performed from January 2010 to January 2012 across 34 centers. A total of 12,804 patients from FRANCE TAVI and 4,165 patients from FRANCE 2 were included in this analysis. The median age of patients was 84.6 years, and 49.7% were men. FRANCE TAVI participants were older but at lower surgical risk (median logistic European System for Cardiac Operative Risk Evaluation [EuroSCORE]: 15.0% vs. 18.4%; p < 0.001). More than 80% of patients in FRANCE TAVI underwent transfemoral TAVR. Transesophageal echocardiography guidance decreased from 60.7% to 32.3% of cases, whereas more recent procedures were increasingly performed in hybrid operating rooms (15.8% vs. 35.7%). Rates of Valve Academic Research Consortium-defined device success increased from 95.3% in FRANCE 2 to 96.8% in FRANCE TAVI (p < 0.001). In-hospital and 30-day mortality rates were 4.4% and 5.4%, respectively, in FRANCE TAVI compared with 8.2% and 10.1%, respectively, in FRANCE 2 (p < 0.001 for both). Stroke and potentially life-threatening complications, such as annulus rupture or aortic dissection, remained stable over time, whereas rates of cardiac tamponade and pacemaker implantation significantly increased. The FRANCE TAVI registry provided reassuring data regarding trends in TAVR performance in an all

  14. 7 CFR 1450.103 - Eligible material that qualifies for payment.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP... this subpart: (1) Eligible material must be renewable biomass that, at a minimum, meets the definition... must be delivered to a qualified biomass conversion facility (as specified in § 1450.101 and other...

  15. 7 CFR 1450.103 - Eligible material that qualifies for payment.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP... this subpart: (1) Eligible material must be renewable biomass that, at a minimum, meets the definition... must be delivered to a qualified biomass conversion facility (as specified in § 1450.101 and other...

  16. 7 CFR 1450.103 - Eligible material that qualifies for payment.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP... this subpart: (1) Eligible material must be renewable biomass that, at a minimum, meets the definition... must be delivered to a qualified biomass conversion facility (as specified in § 1450.101 and other...

  17. 7 CFR 1450.103 - Eligible material that qualifies for payment.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP... this subpart: (1) Eligible material must be renewable biomass that, at a minimum, meets the definition... must be delivered to a qualified biomass conversion facility (as specified in § 1450.101 and other...

  18. Technical Report on the 6th Time Scale Algorithm Symposium and Tutorials

    DTIC Science & Technology

    2016-03-29

    Mesures (BIPM) REPORT NUMBER 12 Bis Grande Rue F-92310 Sevres ( France ) 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S...Authors: F. Arias and G. Panfilo The 6th Time Scale Algorithm Symposium and Tutorials taken place at the Pavilion de Breteuil, BIPM (Sevres, France ) on... France ) 14:30 14:50 Rapid evaluation of time scale using an optical clock (Tetsuya Ida, NICT, Japan) 14:50 15:10 UTC(IT) steering algorithm

  19. 77 FR 54353 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-05

    ... Airworthiness Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for all Eurocopter France... apply to all Eurocopter France (EC) Model SA-365N, SA-365N1, SA-366G1, AS-365N2, AS 365 N3, EC 155B, and...

  20. Temporal evolution of the distribution of hepatitis E virus genotypes in Southwestern France.

    PubMed

    Lhomme, Sebastien; Abravanel, Florence; Dubois, Martine; Chapuy-Regaud, Sabine; Sandres-Saune, Karine; Mansuy, Jean-Michel; Rostaing, Lionel; Kamar, Nassim; Izopet, Jacques

    2015-10-01

    Southwest France is a highly endemic region for hepatitis E virus (HEV). This study examined the circulation of HEV strains between 2003 and 2014 in the Midi-Pyrénées, and compared these data with those from the rest of France. The polyproline region (PPR) of the ORF1 region of the HEV genome was also analyzed. HEV genotype was determined by sequencing a 348-nt fragment within the ORF2 gene for 333 strains in the Midi-Pyrénées and for 571 strains from the rest of France. PPR region was characterized for 56 strains. The frequency of subgenotype 3f decreased over time, whereas subgenotype 3c increased in the Midi-Pyrénées. Repartition of strains did not differ in the Midi-Pyrénées compared to the rest of France. HEV3i and HEV4 have been recently detected throughout France. PPR lengths showed that two major groups of HEV3f exist. Our study shows that HEV3 distribution in the Midi-Pyrénées was similar to the whole of France. Local dietary habits could explain the higher seroprevalence in the Midi-Pyrénées rather the circulation of a particular variant in this region. Copyright © 2015 Elsevier B.V. All rights reserved.

  1. Increased risk of narcolepsy in children and adults after pandemic H1N1 vaccination in France.

    PubMed

    Dauvilliers, Yves; Arnulf, Isabelle; Lecendreux, Michel; Monaca Charley, Christelle; Franco, Patricia; Drouot, Xavier; d'Ortho, Marie-Pia; Launois, Sandrine; Lignot, Séverine; Bourgin, Patrice; Nogues, Béatrice; Rey, Marc; Bayard, Sophie; Scholz, Sabine; Lavault, Sophie; Tubert-Bitter, Pascale; Saussier, Cristel; Pariente, Antoine

    2013-08-01

    An increased incidence of narcolepsy in children was detected in Scandinavian countries where pandemic H1N1 influenza ASO3-adjuvanted vaccine was used. A campaign of vaccination against pandemic H1N1 influenza was implemented in France using both ASO3-adjuvanted and non-adjuvanted vaccines. As part of a study considering all-type narcolepsy, we investigated the association between H1N1 vaccination and narcolepsy with cataplexy in children and adults compared with matched controls; and compared the phenotype of narcolepsy with cataplexy according to exposure to the H1N1 vaccination. Patients with narcolepsy-cataplexy were included from 14 expert centres in France. Date of diagnosis constituted the index date. Validation of cases was performed by independent experts using the Brighton collaboration criteria. Up to four controls were individually matched to cases according to age, gender and geographic location. A structured telephone interview was performed to collect information on medical history, past infections and vaccinations. Eighty-five cases with narcolepsy-cataplexy were included; 23 being further excluded regarding eligibility criteria. Of the 62 eligible cases, 59 (64% males, 57.6% children) could be matched with 135 control subjects. H1N1 vaccination was associated with narcolepsy-cataplexy with an odds ratio of 6.5 (2.1-19.9) in subjects aged<18 years, and 4.7 (1.6-13.9) in those aged 18 and over. Sensitivity analyses considering date of referral for diagnosis or the date of onset of symptoms as the index date gave similar results, as did analyses focusing only on exposure to ASO3-adjuvanted vaccine. Slight differences were found when comparing cases with narcolepsy-cataplexy exposed to H1N1 vaccination (n=32; mostly AS03-adjuvanted vaccine, n=28) to non-exposed cases (n=30), including shorter delay of diagnosis and a higher number of sleep onset rapid eye movement periods for exposed cases. No difference was found regarding history of infections. In

  2. Enterovirus Migration Patterns between France and Tunisia

    PubMed Central

    Othman, Ines; Mirand, Audrey; Slama, Ichrak; Mastouri, Maha; Peigue-Lafeuille, Hélène; Aouni, Mahjoub; Bailly, Jean-Luc

    2015-01-01

    The enterovirus (EV) types echovirus (E-) 5, E-9, and E-18, and coxsackievirus (CV-) A9 are infrequently reported in human diseases and their epidemiologic features are poorly defined. Virus transmission patterns between countries have been estimated with phylogenetic data derived from the 1D/VP1 and 3CD gene sequences of a sample of 74 strains obtained in France (2000–2012) and Tunisia (2011–2013) and from the publicly available sequences. The EV types (E-5, E-9, and E-18) exhibited a lower worldwide genetic diversity (respective number of genogroups: 4, 5, and 3) in comparison to CV-A9 (n = 10). The phylogenetic trees estimated with both 1D/VP1 and 3CD sequence data showed variations in the number of co-circulating lineages over the last 20 years among the four EV types. Despite the low number of genogroups in E-18, the virus exhibited the highest number of recombinant 3CD lineages (n = 10) versus 4 (E-5) to 8 (E-9). The phylogenies provided evidence of multiple transportation events between France and Tunisia involving E-5, E-9, E-18, and CV-A9 strains. Virus spread events between France and 17 other countries in five continents had high probabilities of occurrence as those between Tunisia and two European countries other than France. All transportation events were supported by BF values > 10. Inferring the source of virus transmission from phylogenetic data may provide insights into the patterns of sporadic and epidemic diseases caused by EVs. PMID:26709514

  3. Enterovirus Migration Patterns between France and Tunisia.

    PubMed

    Othman, Ines; Mirand, Audrey; Slama, Ichrak; Mastouri, Maha; Peigue-Lafeuille, Hélène; Aouni, Mahjoub; Bailly, Jean-Luc

    2015-01-01

    The enterovirus (EV) types echovirus (E-) 5, E-9, and E-18, and coxsackievirus (CV-) A9 are infrequently reported in human diseases and their epidemiologic features are poorly defined. Virus transmission patterns between countries have been estimated with phylogenetic data derived from the 1D/VP1 and 3CD gene sequences of a sample of 74 strains obtained in France (2000-2012) and Tunisia (2011-2013) and from the publicly available sequences. The EV types (E-5, E-9, and E-18) exhibited a lower worldwide genetic diversity (respective number of genogroups: 4, 5, and 3) in comparison to CV-A9 (n = 10). The phylogenetic trees estimated with both 1D/VP1 and 3CD sequence data showed variations in the number of co-circulating lineages over the last 20 years among the four EV types. Despite the low number of genogroups in E-18, the virus exhibited the highest number of recombinant 3CD lineages (n = 10) versus 4 (E-5) to 8 (E-9). The phylogenies provided evidence of multiple transportation events between France and Tunisia involving E-5, E-9, E-18, and CV-A9 strains. Virus spread events between France and 17 other countries in five continents had high probabilities of occurrence as those between Tunisia and two European countries other than France. All transportation events were supported by BF values > 10. Inferring the source of virus transmission from phylogenetic data may provide insights into the patterns of sporadic and epidemic diseases caused by EVs.

  4. 78 FR 9777 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-12

    ... Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA), Department of... airworthiness directive (AD) for Eurocopter France (Eurocopter) Model EC 155B, EC155B1, SA-365N1, AS-365N2 and... aviation authority of France and are approved for operation in the United States. Pursuant to our bilateral...

  5. Nitrogen food-print: N use related to meat and dairy consumption in France

    NASA Astrophysics Data System (ADS)

    Chatzimpiros, P.; Barles, S.

    2013-01-01

    Human foods typically contain a minor fraction of the nitrogen (N) used in agricultural production. The major fraction is lost to the environment and interferes with all current environmental problems and global change issues. Food is also generally consumed far from its production location and associated N losses remain unknown unless connected to products through consumption-based indicators. We develop the N food-print as an indicator to connect N flows and losses in livestock systems to the consumption of dietary N in the form of beef, pork and fresh milk in France. This N food-print of a product is the N loss associated with its agricultural production. The conversions of N, from field application to recovery in vegetal and animal proteins, are calculated from statistical data on crop and animal production and through modelling of feed rations for cattle and swine. Beef farming to feed an individual in France uses 11.1 kg N cap-1 yr-1, out of which 3.8 kg N cap-1 yr-1 (or 35%) is the N food-print, 7% is recovered in retail products, 3% is slaughter waste and 55% returns to agriculture as manure. Pork and dairy production use 7.5 and 2.3 kg N cap-1 yr-1, respectively, out of which 53 and 48% is the N food-print, respectively; about 11% is recovered in retail products and 35% returns to agriculture as manure. In total, more than 75% of the N food-print relates to crop cultivation for feed and much of these losses (80% for dairy and pork production, 20% for beef production) occur in crop farms far from where the livestock is reared. Regional and national policies to reduce N losses should take into account that trade in feed implies causal relationships among N losses in agrosystems distant from each other.

  6. 75 FR 63052 - Airworthiness Directives; Eurocopter France (ECF) Model AS350B3 and EC130 B4 Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-14

    ... Airworthiness Directives; Eurocopter France (ECF) Model AS350B3 and EC130 B4 Helicopters AGENCY: Federal... directive (AD) for the Eurocopter France Model AS350B3 and EC130 B4 helicopters. This amendment is prompted... autorotation training making it impossible to execute a power recovery and compelling the pilot to continue the...

  7. SIX MORE QUASARS AT REDSHIFT 6 DISCOVERED BY THE CANADA-FRANCE HIGH-z QUASAR SURVEY

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Willott, Chris J.; Crampton, David; Hutchings, John B.

    2009-03-15

    We present imaging and spectroscopic observations for six quasars at z {>=} 5.9 discovered by the Canada-France High-z Quasar Survey (CFHQS). The CFHQS contains subsurveys with a range of flux and area combinations to sample a wide range of quasar luminosities at z {approx} 6. The new quasars have luminosities 10-75 times lower than the most luminous Sloan Digital Sky Survey quasars at this redshift. The least luminous quasar, CFHQS J0216-0455 at z = 6.01, has absolute magnitude M {sub 1450} = -22.21, well below the likely break in the luminosity function. This quasar is not detected in a deepmore » XMM-Newton survey showing that optical selection is still a very efficient tool for finding high-redshift quasars.« less

  8. The ceramics of Malpaís of Zacapu, Michoacán, Mexico, during the Early and Middle Postclassic periods (900-1450 AD): Micro-chemical characterization of surface paintings

    NASA Astrophysics Data System (ADS)

    Jadot, E.; Schiavon, N.; Manso, M.

    2016-05-01

    Tarascan ceramic sherds from two Postclassical archaeological sites (900-1450 AD) at the Malpaís of Zacapu, Michoacán, Mexico, were investigated by combining Back-Scattered Scanning Electron Microscopy and Energy Dispersive Spectroscopy (BSEM-EDS), μ-X-Ray Diffractometry (μ-XRD), μ-X-ray Fluorescence Spectroscopy (μ-XRF) and μ-Raman Spectroscopy. These sherds are famous for their forms and decorations although the composition of its raw materials remains so far unknown and focused only on the composition of the ceramic paste. For the purpose of surface decoration characterization, the pigments used in slips and paintings were identified as hematite, magnetite, amorphous carbon, graphite and lignite. Furthermore chemical and molecular structure determination allowed the identification of technological aspects such as the firing temperatures and atmospheres used in ceramics production.

  9. Quasi-two-body decays Bc → D(s)[ρ(770),ρ(1450),ρ(1700)→]ππ in the perturbative QCD factorization approach

    NASA Astrophysics Data System (ADS)

    Ma, Ai-Jun; Li, Ya; Xiao, Zhen-Jun

    2018-01-01

    In this paper, we studied the quasi-two-body Bc →D(s) [ ρ (770) , ρ (1450) , ρ (1700) → ] ππ decays by employing the perturbative QCD (PQCD) factorization approach. The two-pion distribution amplitudes Φππ are applied to include the final-state interactions between the pion pair, while the time-like form factors Fπ (w2) associated with the P-wave resonant states ρ (770), ρ (1450) and ρ (1700) are extracted from the experimental data of the e+e- annihilation. We found that: (a) the PQCD predictions for the branching ratios of the quasi-two-body Bc →D(s) [ ρ (770) , ρ (1450) , ρ (1700) → ] ππ decays are in the order of 10-9 to 10-5 and the direct CP violations around (10 - 40)% in magnitude; (b) the two sets of the large hierarchy R 1 a , 1 b , 1 c and R 2 a , 2 b , 2 c for the ratios of the branching ratios of the considered decays are defined and can be understood in the PQCD factorization approach, while the self-consistency between the quasi-two-body and two-body framework for Bc →D(s) [ ρ (770) → ] ππ and Bc →D(s) ρ (770) decays are confirmed by our numerical results; (c) taking currently known B (ρ (1450) → ππ) and B (ρ (1700) → ππ) as input, we extracted the theoretical predictions for B (Bc → Dρ (1450)) and B (Bc → Dρ (1700)) from the PQCD predictions for the decay rates of the quasi-two-body decays Bc → D [ ρ (1450) , ρ (1700) → ] ππ. All the PQCD predictions will be tested in the future experiments.

  10. Mortality burden of the 2009 A/H1N1 influenza pandemic in France: comparison to seasonal influenza and the A/H3N2 pandemic.

    PubMed

    Lemaitre, Magali; Carrat, Fabrice; Rey, Grégoire; Miller, Mark; Simonsen, Lone; Viboud, Cécile

    2012-01-01

    The mortality burden of the 2009 A/H1N1 pandemic remains unclear in many countries due to delays in reporting of death statistics. We estimate the age- and cause-specific excess mortality impact of the pandemic in France, relative to that of other countries and past epidemic and pandemic seasons. We applied Serfling and Poisson excess mortality approaches to model weekly age- and cause-specific mortality rates from June 1969 through May 2010 in France. Indicators of influenza activity, time trends, and seasonal terms were included in the models. We also reviewed the literature for country-specific estimates of 2009 pandemic excess mortality rates to characterize geographical differences in the burden of this pandemic. The 2009 A/H1N1 pandemic was associated with 1.0 (95% Confidence Intervals (CI) 0.2-1.9) excess respiratory deaths per 100,000 population in France, compared to rates per 100,000 of 44 (95% CI 43-45) for the A/H3N2 pandemic and 2.9 (95% CI 2.3-3.7) for average inter-pandemic seasons. The 2009 A/H1N1 pandemic had a 10.6-fold higher impact than inter-pandemic seasons in people aged 5-24 years and 3.8-fold lower impact among people over 65 years. The 2009 pandemic in France had low mortality impact in most age groups, relative to past influenza seasons, except in school-age children and young adults. The historical A/H3N2 pandemic was associated with much larger mortality impact than the 2009 pandemic, across all age groups and outcomes. Our 2009 pandemic excess mortality estimates for France fall within the range of previous estimates for high-income regions. Based on the analysis of several mortality outcomes and comparison with laboratory-confirmed 2009/H1N1 deaths, we conclude that cardio-respiratory and all-cause mortality lack precision to accurately measure the impact of this pandemic in high-income settings and that use of more specific mortality outcomes is important to obtain reliable age-specific estimates.

  11. Women in physics in France

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pierron-Bohnes, Véronique

    We present six associations and entities working in France on issues of women in physics: the Women and Physics Commission, French Physical Society; Women in Nuclear (WiN) France; Women and Science Association; Mission for the Place of Women at CNRS; Parity, Diversity, and Women Network, CEA; and the Network of University Equality-Diversity Representatives.

  12. 77 FR 36213 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-18

    ...-0630; Directorate Identifier 2011-SW-010-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France EC130B4 helicopters... unsafe condition for the Eurocopter France EC130B4 helicopters. EASA states that it received reports that...

  13. NO(y) Correlation with N2O and CH4 in the Midlatitude Stratosphere

    NASA Technical Reports Server (NTRS)

    Kondo, Y.; Schmidt, U.; Sugita, T.; Engel, A.; Koike, M.; Aimedieu, P.; Gunson, M. R.; Rodriguez, J.

    1996-01-01

    Total reactive nitrogen (NO(y)), nitrous oxide (NO2), methane (CH4), and ozone (03) were measured on board a balloon launched from Aire sur l'Adour (44 deg N, 0 deg W), France on October 12, 1994. Generally, NO(y) was highly anti-correlated with N2O and CH4 at altitudes between 15 and 32 km. The linear NO(y) - N2O and NO(y) - CH4 relationships obtained by the present observations are very similar to those obtained on board ER-2 and DC-8 aircraft previously at altitude below 20 km in the northern hemisphere. They also agree well with the data obtained by the Atmospheric Trace Molecule Spectroscopy (ATMOS) instrument at 41 deg N in November 1994. Slight departures from linear correlations occurred around 29 km, where N2O and CH4 mixing ratios were larger than typical midlatitude values, suggesting horizontal transport of tropical airmasses to northern midlatitudes in a confined altitude region.

  14. 78 FR 70202 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-25

    ... Airworthiness Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA), DOT... France (Eurocopter) Model AS350B, BA, B1, B2, B3, D, AS355E, F, F1, F2, and N [[Page 70203

  15. France. Country profile. [France's economy adjusts to a declining birth rate].

    PubMed

    Inserra, P

    1984-09-01

    This discussion of France focuses on regions and cities, age distribution, households and families, housing, labor force, consumption, education, and communications. France counted 54,334,871 citizens as of March 4, 1982. There were 250,000 more people than in 1975, yielding a 7-year growth rate of 3.3%. If present trends continue, there will be 56 million French by the end of the 1980s. Since 1975 when the last census was conducted, cities of more than 200,000 lost an average of 5% of their residents. For the 1st time in more than a century, urban areas of 20,000 or more did not gain population but merely held their own. France continues to experience the effects of the large-scale decimation of its male population during the 2 world wars. The World war i loss showed up March 1982 as a relatively smaller 60-74 group. Conversely the population aged 75 and over is growing, both in absolute numbers and as a percent of the population. There were 3.6 million aged 75 and over (6.6% of the population) in 1982 compared with 3 million (5.6%) in 1975. The 19 and under age group declined between 1975-85, from 31% (16.2 million) to 29% (15.6 million). The 20-59 year old group constitutes the largest segment of the population--about double the group aged 19 and under--and its growing. This group was 50% of the population in 1973 and 53% in 1982. The infant mortality rate has declined steadily in France, from 18.2 deaths/1000 births in 1970 to 13.6 in 1975 and 9.5 at present. The total fertility rate has continued to decline: 1.8 children/woman in the 1982 census a rate less than the number needed to replace the present French population. Between 1975-82 households grew 10.4% to a total of 19.6 million. The growth in the number of households is attributed to the increase in divorce and the tendency for French children to leave the parental home at an earlier age. France has nearly 23 million dwelling places. More than half of householders own their own homes. New housing starts

  16. COLLEGIUM INTERNATIONALE NEURO-PSYCHOPHARMACOLOGICUM (C.I.N.P.) 24th CONGRESS (Paris, France, 20-24 June 2004).

    PubMed

    Pivac, Nela

    2004-09-01

    The 24th C.I.N.P. meeting was held in Paris, France, from June 20-24, 2004. The opening ceremony and welcome reception was chaired by Professor Herbert Y Meltzer, Vanderbilt University, Nashville, TN, USA, President of C.I.N.P., and a new president was elected (Professor Brian E. Leonard, Ireland). Congress included the rich social program, combined with lectures of invited speakers, speeches and awards. There were 6650 registered participants all over the world. The meeting consisted of 4 plenary lectures (held by Professor FE Bloom, Department of Neuropharmacology, The Scripps Research Institute, La Jolla USA, Professor HY Meltzer, Vanderbilt University, Nashville, TN, USA, Professor CL Masters, The University of Melbourne, and the Mental Health Research Institute of Victoria, Melbourne, Australia, and Professor JP Changeux, CNRS URA 2182 Recepteurs and Cognition, Paris, France), 69 symposia, 5 synthesia, 25 satellite symposia, 2 electronic interactive sessions, 6 meet the expert sessions, 11 sessions that were held under the name breaking scientific news, 6 workshops, 5 joint meetings, and 2 poster sessions with 657 posters. Posters were displayed for 2 days between 12.00 to 18.00 h, and presenters were available between 16.30 and 18.00 h to answer the questions. Abstracts from the congress were published in International Journal of Neuropsychopharmacology, vol 7, Supplement 1, June 2004. The 24th Collegium Internationale Neuro-Psychopharmacologicum (C.I.N.P.) Congress introduced some new exciting data, summarized some new knowledge, and its goal was to connect the preclinical and clinical data and to introduce some news into clinical practice. The smaller part of the congress that I was able to follow was well organized, and very good attended, with diverse topics, covering all aspects of neuropsychopharmacological research. The sponsorship by the pharmaceutical industries was visible only in the selected sponsored symposia.

  17. Comparison of aryl hydrocarbon hydroxylase and acetanilide 4-hydroxylase induction by polycyclic aromatic compounds in human and mouse cell lines.

    PubMed

    Jaiswal, A K; Nebert, D W; Eisen, H W

    1985-08-01

    The human MCF-7 and the mouse Hepa-1 cell culture lines were compared for aryl hydrocarbon hydroxylase and acetanilide 4-hydroxylase inducibility by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and benzo[a]anthracene (BA) and TCDD- and BA-specific binding in the cytosol and nucleus. The effective concentration of BA in the growth medium required to induce either enzyme to 50% of its maximally inducible activity (EC50) was the same (5-11 microM) in both MCF-7 and Hepa-1 cells. On the other hand, the EC50 for TCDD in MCF-7 cells (5-25 nM) was more than 40-fold greater than that in Hepa-1 cells (0.4 to 0.6 nM). P1-450- and P3-450-specific mouse cDNA probes were used to quantitate mRNA induction in the Hepa-1 cell line. P1-450 mRNA was induced markedly by TCDD and benzo[a] anthracene, whereas P3-450 mRNA was induced negligibly. A P1-450-specific human cDNA probe was used to quantitate P1-450 mRNA induction in the MCF-7 cell line. Aryl hydrocarbon hydroxylase inducibility by TCDD or BA always paralleled P1-450 mRNA inducibility in either the mouse or human line. Although the cytosolic Ah receptor in Hepa-1 cells was easily detected by sucrose density gradient centrifugation, gel permeation chromatography, and anion-exchange high-performance liquid chromatography, the cytosolic receptor cannot be detected in MCF-7 cells. Following in vivo exposure of cultures to radiolabeled TCDD, the intranuclear concentration of inducer-receptor complex was at least fifty times greater in Hepa-1 than MCF-7 cultures. The complete lack of measurable cytosolic receptor and almost totally absent inducer-receptor complex in the nucleus of MCF-7 cells was, therefore, out of proportion to its capacity for aryl hydrocarbon hydroxylase and acetanilide 4-hydroxylase inducibility. This MCF-7 line should provide an interesting model for a better understanding of the mechanisms of drug-metabolizing enzyme induction by polycyclic aromatic compounds, including the Ah receptor-mediated mechanism.

  18. KSC-2009-1450

    NASA Image and Video Library

    2009-01-14

    VANDENBERG AIR FORCE BASE, Calif. -- In Bldg. 1610 at Vandenberg Air Force Base in California, the covered NOAA-N Prime spacecraft is lowered onto a transporter. NOAA-N Prime is the latest polar-orbiting operational environmental weather satellite developed by NASA for the National Oceanic and Atmospheric Administration. The satellite is scheduled to launch Feb. 4 aboard a Delta II rocket from Vandenberg Air Force Base. Photo credit: NASA/ Daniel Liberotti, VAFB

  19. 77 FR 5994 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-07

    ... Airworthiness Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA... airworthiness directive (AD) for all Eurocopter France EC130B4 helicopters that have not had Eurocopter... actions. FAA's Determination These helicopters have been approved by the aviation authority of France and...

  20. 78 FR 1739 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-09

    ... Airworthiness Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for all Eurocopter France... Directorate General for Civil Aviation (DGAC France) AD F-2008-04, dated June 4, 2008, for the Eurocopter...

  1. Stratospheric N2O5, CH4, and N2O profiles from IR solar occultation spectra

    NASA Technical Reports Server (NTRS)

    Camy-Peyret, C.; Flaud, J.-M.; Perrin, A.; Rinsland, C. P.; Goldman, A.; Murcray, F. J.

    1993-01-01

    Stratospheric volume mixing ratio profiles of N2O5, CH4, and N2O have been retrieved from a set of 0.052/cm resolution (FWHM) solar occultation spectra recorded at sunrise during a balloon flight from Aire sur l'Adour, France (44 N latitude) on 12 October 1990. The N2O5 results have been derived from measurements of the integrated absorption by the 1246/cm band. Assuming a total intensity of 4.32 x 10 exp -17 cm/molecule/sq cm independent of temperature, the retrieved N2O5 volume mixing ratios in ppbv, interpolated to 2 km height spacings, are 1.64 +/- 0.49 at 37.5 km, 1.92 +/- 0.56 at 35.5 km, 2.06 +/- 0.47 at 33.5 km, 1.95 +/- 0.42 at 31.5 km, 1.60 +/- 0.33 at 29.5 km, 1.26 +/- 0.28 at 27.5 km, and 0.85 +/- 0.20 at 25.5 km. Error bars indicate the estimated 1-sigma uncertainty including the error in the total band intensity. The retrieved profiles are compared with previous measurements and photochemical model results.

  2. 4TH International Topical Conference on High-Power Electron and Ion-Beam Research and Technology, held in Palaiseau, France, 29 June - 3 July 1981.

    DTIC Science & Technology

    1981-10-09

    N. Camarcat (Centre d’Etudes de Valduc ) noted that the French were new in this field and presented the results of the experiments on LIB production...Beam Production on Low Impedance Generators" N. Camarcat et al. C.E.A.-D.A.M.-S.E.C.R. Centre d’Etudes de Valduc , France 7...Acceleration on the Thalie Generator" J. Cortella et al. C.E.A.-D.A.M.-S.E.C.R. Centre d’Etudes de Valduc , France ION PRODUCTION II "The Work on High

  3. [Anesthesiologists in France].

    PubMed

    Mizuno, Ju; Hanaoka, Kazuo; Merckx, Paul; Bonneville, Claire Tae; Kavafyan, Juliette; Mantz, Jean

    2007-03-01

    We review some anesthesiologist's curriculum and demographic characteristics in France to the community of Japanese anesthesiologists. To become a certified anesthesiologist and an intensive care physician currently requires six years' medical education, passing national medical examination, and five years' special training as an intern of anesthesiology and intensive care. This educational course was started in 1984. There are 7942 certified anesthesiologists in France in 1999. The average age is 45.9 years and the ratio of female is 35.3%. Approximately two thirds of certified anesthesiologists are working in public institutions. 89% is full-time workers. More than half of certified anesthesiologists actually participate in daily intensive care practice. The number of certified anesthesiologists has been increasing gradually totaling 10,062 persons in 2005. The number of certified anesthesiologists per ten thousands general population is 1.7 persons and the corresponding ratio to all medical doctors is 4.8%. Working hours and holidays are regulated by the French Labour Law. The anaesthesiologist often works in a team with a nurse anaesthetist. The number of certified anesthesiologists in France is larger than that in Japan. Management of anesthesia in France seems to have an advantage in manpower.

  4. Molecular epidemiology of penicillinase-producing Neisseria gonorrhoeae isolates in France.

    PubMed

    Micaëlo, M; Goubard, A; La Ruche, G; Denamur, E; Tenaillon, O; Cambau, E; Jacquier, H; Bercot, B

    2017-12-01

    Characterizing the molecular epidemiology of antibiotic resistance is crucial for a better understanding of the evolution and spread of resistance in Neisseria gonorrhoeae. Here, we examine the molecular epidemiology of penicillinase-producing N. gonorrhoeae (PPNG) isolates in France. We investigated 176 PPNG isolates collected between 2010 and 2012 by the National Reference Centre in France. Genotyping was performed using the NG-MAST technique, bla TEM genes were Sanger-sequenced, and plasmids were characterized by PCR-typing. We revealed the existence of four major clusters representing about one-third of PPNG circulating in France. These clusters were related to ST1479 (18/176, 10.2%), to ST1582 (15/176, 8.5%), to ST8922 (10/176, 5.6%), and to ST1285 (9/176, 5.1%). Wild-type TEM-1 was identified in 151 (151/176, 85.8%) PPNG isolates, and TEM-1 variants were mostly represented by the M182T mutation (14/176, 8%), followed by P14S/L (8/176, 4.5%), G228S (2/176, 1.1%), and Q269K (1/176, 0.6%). The bla TEM genes were carried by African (157/176, 89.2%), Asian (13/176, 7.4%), and Toronto/Rio (6/176, 3.4%) plasmids. The M182T variants were found in various genetic backgrounds, whereas the P14S variants were disseminated clonally. The G228S and Q269K variants belong to one of the four major clusters of PPNG, which suggests a recent de novo emergence of these mutations. Our results show that approximately one-third of the penicillinase-producing N. gonorrhoeae isolates in France belong to one of four major clusters and that the spread of the different TEM variants is associated with distinct patterns of molecular epidemiology. Copyright © 2017 European Society of Clinical Microbiology and Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

  5. Geographical Heterogeneity of Multiple Sclerosis Prevalence in France.

    PubMed

    Pivot, Diane; Debouverie, Marc; Grzebyk, Michel; Brassat, David; Clanet, Michel; Clavelou, Pierre; Confavreux, Christian; Edan, Gilles; Leray, Emmanuelle; Moreau, Thibault; Vukusic, Sandra; Hédelin, Guy; Guillemin, Francis

    2016-01-01

    Geographical variation in the prevalence of multiple sclerosis (MS) is controversial. Heterogeneity is important to acknowledge to adapt the provision of care within the healthcare system. We aimed to investigate differences in prevalence of MS in departments in the French territory. We estimated MS prevalence on October 31, 2004 in 21 administrative departments in France (22% of the metropolitan departments) by using multiple data sources: the main French health insurance systems, neurologist networks devoted to MS and the Technical Information Agency of Hospitalization. We used a spatial Bayesian approach based on estimating the number of MS cases from 2005 and 2008 capture-recapture studies to analyze differences in prevalence. The age- and sex-standardized prevalence of MS per 100,000 inhabitants ranged from 68.1 (95% credible interval 54.6, 84.4) in Hautes-Pyrénées (southwest France) to 296.5 (258.8, 338.9) in Moselle (northeast France). The greatest prevalence was in the northeast departments, and the other departments showed great variability. By combining multiple data sources into a spatial Bayesian model, we found heterogeneity in MS prevalence among the 21 departments of France, some with higher prevalence than anticipated from previous publications. No clear explanation related to health insurance coverage and hospital facilities can be advanced. Population migration, socioeconomic status of the population studied and environmental effects are suspected.

  6. 77 FR 36220 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-18

    ...-0632; Directorate Identifier 2011-SW-044-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for all Eurocopter France (Eurocopter... Civil Aviation (DGAC France) AD F-2008-04, dated June 4, 2008, for the Eurocopter Model EC 155 B, EC 155...

  7. Stratospheric N2O5, CH4, and N2O Profiles from IR Solar Occultation Spectra

    NASA Technical Reports Server (NTRS)

    Peyeret, C. Camy; Flaud, J.-M.; Perrin, A.; Rinsland, C. P.; Goldman, A.; Murcray, F. J.

    1993-01-01

    Stratospheric volume mixing ratio profiles of N2O5, CH4, and N2O have been retrieved from a set of 0.052/ cm resolution (FWHM) solar occultation spectra recorded at sunrise during a balloon flight from Aire sur I'Adour, France (44 deg N latitude) on 12 October 1990. The N2O5 results have been derived from measurements of the integrated absorption by the 1246/ cm band. Assuming a total intensity of 4.32 x 10(exp 17)cm(exp -1) molecule sq cm(exp -2) independent of temperature, the retrieved N2O5 volume mixing ratios in ppbv (parts per billion by volume, 10(exp -9)), interpolated to 2 km height spacings, are 1.64 +/- 0.49 at 37.5 km, 1.92 +/- 0.56 at 35.5 km, 2.06 +/- 0.47 at 33.5 km, 1.95 +/- 0.42 at 31.5 km, 1.60 +/- 0.33 at 29.5 km, 1.26 +/- 0.28 at 27.5 km, and 0.85 +/- 0.20 at 25.5 km. Error bars indicate the estimated I-sigma uncertainty including the error in the total band intensity (+/- 20% has been assumed). The retrieved profiles are compared with previous measurements and photochemical model results.

  8. Prevalence of pain medication prescriptions in France, Germany, and the UK - a cross-sectional study including 4,270,142 patients.

    PubMed

    Jacob, Louis; Kostev, Karel

    2018-01-01

    The goal of the present study was to analyze the prevalence of pain medication prescriptions in general practices in France, Germany, and the UK. This study included all patients aged ≥18 years followed in 2016 in general practitioner practices in France, Germany and the UK. The primary outcome was the prevalence of patients receiving prescriptions for pain medications in France, Germany, and the UK in 2016. The following drugs were included in the analysis: anti-inflammatory and antirheumatic products, non-steroids and analgesics including opioids, antimigraine preparations, and other analgesics and antipyretics. Demographic variables included age and gender. This study included 4,270,142 patients. The prevalences of pain medication prescriptions were 57.3% in France, 29.6% in Germany, and 21.7% in the UK. Although this prevalence generally remained consistent between age groups in France (54.3%-60.3%), it increased with age in Germany (18-30 years: 23.8%; >70 years: 35.8%) and in the UK (18-30 years: 9.3%; >70 years: 43.8%). Finally, the prevalence of pain medication prescriptions was higher in women than in men in all three countries. Paracetamol was prescribed to 82.3% and 60.1% of patients receiving pain medication in France and the UK, respectively, whereas ibuprofen was prescribed to 46.5% of individuals in Germany. The prevalence of pain medication prescriptions was higher in France than in Germany and the UK. Further research is needed to gain a better understanding of the differences in the prescription patterns between these three European countries.

  9. The sex-selective impact of the Black Death and recurring plagues in the Southern Netherlands, 1349-1450.

    PubMed

    Curtis, Daniel R; Roosen, Joris

    2017-10-01

    Although recent work has begun to establish that early modern plagues had selective mortality effects, it was generally accepted that the initial outbreak of Black Death in 1347-52 was a "universal killer." Recent bioarchaeological work, however, has argued that the Black Death was also selective with regard to age and pre-plague health status. The issue of the Black Death's potential sex selectivity is less clear. Bioarchaeological research hypothesizes that sex-selection in mortality was possible during the initial Black Death outbreak, and we present evidence from historical sources to test this notion. To determine whether the Black Death and recurring plagues in the period 1349-1450 had a sex-selective mortality effect. We present a newly compiled database of mortality information taken from mortmain records in Hainaut, Belgium, in the period 1349-1450, which not only is an important new source of information on medieval mortality, but also allows for sex-disaggregation. We find that the Black Death period of 1349-51, as well as recurring plagues in the 100 years up to 1450, often had a sex-selective effect-killing more women than in "non-plague years." Although much research tends to suggest that men are more susceptible to a variety of diseases caused by bacteria, viruses and parasites, we cannot assume that the same direction of sex-selection in mortality applied to diseases in the distant past such as Second Pandemic plagues. While the exact reasons for the sex-selective effect of late-medieval plague are unclear in the absence of further data, we suggest that simple inequities between the sexes in exposure to the disease may not have been a key driver. © 2017 Wiley Periodicals, Inc.

  10. Airborne Detection of H5N8 Highly Pathogenic Avian Influenza Virus Genome in Poultry Farms, France.

    PubMed

    Scoizec, Axelle; Niqueux, Eric; Thomas, Rodolphe; Daniel, Patrick; Schmitz, Audrey; Le Bouquin, Sophie

    2018-01-01

    In southwestern France, during the winter of 2016-2017, the rapid spread of highly pathogenic avian influenza H5N8 outbreaks despite the implementation of routine control measures, raised the question about the potential role of airborne transmission in viral spread. As a first step to investigate the plausibility of that transmission, air samples were collected inside, outside and downwind from infected duck and chicken facilities. H5 avian influenza virus RNA was detected in all samples collected inside poultry houses, at external exhaust fans and at 5 m distance from poultry houses. For three of the five flocks studied, in the sample collected at 50-110 m distance, viral genomic RNA was detected. The measured viral air concentrations ranged between 4.3 and 6.4 log 10 RNA copies per m 3 , and their geometric mean decreased from external exhaust fans to the downwind measurement point. These findings are in accordance with the possibility of airborne transmission and question the procedures for outbreak depopulation.

  11. Airborne Detection of H5N8 Highly Pathogenic Avian Influenza Virus Genome in Poultry Farms, France

    PubMed Central

    Scoizec, Axelle; Niqueux, Eric; Thomas, Rodolphe; Daniel, Patrick; Schmitz, Audrey; Le Bouquin, Sophie

    2018-01-01

    In southwestern France, during the winter of 2016–2017, the rapid spread of highly pathogenic avian influenza H5N8 outbreaks despite the implementation of routine control measures, raised the question about the potential role of airborne transmission in viral spread. As a first step to investigate the plausibility of that transmission, air samples were collected inside, outside and downwind from infected duck and chicken facilities. H5 avian influenza virus RNA was detected in all samples collected inside poultry houses, at external exhaust fans and at 5 m distance from poultry houses. For three of the five flocks studied, in the sample collected at 50–110 m distance, viral genomic RNA was detected. The measured viral air concentrations ranged between 4.3 and 6.4 log10 RNA copies per m3, and their geometric mean decreased from external exhaust fans to the downwind measurement point. These findings are in accordance with the possibility of airborne transmission and question the procedures for outbreak depopulation. PMID:29487857

  12. A clinical investigation of the efficacy of a dentifrice containing 1.5% arginine and 1450 ppm fluoride, as sodium monofluorophosphate in a calcium base, on primary root caries.

    PubMed

    Hu, D Y; Yin, W; Li, X; Feng, Y; Zhang, Y P; Cummins, D; Mateo, L R; Ellwood, R P

    2013-01-01

    The purpose of this six-month study was to assess the ability of a new dentifrice containing 1.5% arginine, an insoluble calcium compound, and 1450 ppm fluoride, as sodium monofluorophosphate, to arrest and reverse primary root caries lesions in adults. Three test groups used dentifrices which contained either: 1) 1.5% arginine and 1450 ppm fluoride as sodium monofluorophosphate in a calcium base (experimental); 2) 1450 ppm fluoride as sodium fluoride in a silica base (positive control); or 3) no fluoride in a calcium base (negative control). The study participants were residents of the city of Chengdu, Sichuan Province, China. In order to take part, subjects had to have at least one non-cavitated primary root caries lesion. A total of 412 subjects completed the study. They were aged from 50 to 70 years (mean age 64 +/- 4.1 years) and 53.6% were female. Efficacy for arresting and reversal of primary root caries was assessed by clinical hardness measures and through the use of the Electrical Caries Monitor. After three months of product use, clinical hardness measures showed that 27.7%, 24.6%, and 13.1% of lesions had improved in the experimental, positive, and negative control groups, respectively, and 0.7%, 4.5%, and 16.8% had become worse, respectively. The differences in the distribution of lesion change between the negative control group and both the experimental (p < 0.001) and positive control (p = 0.001) were statistically significant. The Electrical Caries Monitor was also used as an objective measure of lesion severity. The end values increased from baseline to the three-month examinations, but none of the differences between the groups attained statistical significance. After six months, clinical hardness measures showed that only one lesion (0.7%) was worse than at the baseline examination-in the experimental group compared to 9.0% and 18.2% in the positive and negative control groups, respectively. In addition, 61.7%, 56.0%, and 27.0%, respectively

  13. Predictive factors of cytomegalovirus seropositivity among pregnant women in Paris, France.

    PubMed

    N'Diaye, Dieynaba S; Yazdanpanah, Yazdan; Krivine, Anne; Andrieu, Thibaut; Rozenberg, Flore; Picone, Olivier; Tsatsaris, Vassilis; Goffinet, François; Launay, Odile

    2014-01-01

    Cytomegalovirus (CMV) is the most frequent cause of congenital infection. The objective of this study was to evaluate predictive factors for CMV seronegativity in a cohort of pregnant women in Paris, France. Pregnant women enrolled in a prospective cohort during the 2009 A/H1N1 pandemic were tested for CMV IgG antibodies. Variables collected were age, geographic origin, lifestyle, work characteristics, socioeconomic status, gravidity, parity and number of children at home. A multivariate logistic regression model was used to identify independent predictive factors for CMV seropositivity. Among the 826 women enrolled, 389 (47.1%) were primiparous, and 552 (67.1%) had Metropolitan France as a geographic origin. Out of these, 355 (i.e. 57.0%, 95% confidence interval (CI): [53.6%-60.4%]) were CMV seropositive: 43.7% (95% CI:[39.5%-47.9%]) in those whose geographic origin was Metropolitan France and 84.1% in those with other origins (95% CI:[79.2%-88.3%]). Determinants associated with CMV seropositivity in a multivariate logistic regression model were: (i) geographic origin (p<0.001(compared with Metropolitan France, geographic origins of Africa adjusted odds ratio (aOR) 21.2, 95% CI:[9.7-46.5], French overseas departments and territories and other origin, aOR 7.5, 95% CI:[3.9-14.6], and Europe or Asia, aOR 2.2, 95% CI: [1.3-3.7]); and (ii) gravidity (p = 0.019), (compared with gravidity = 1, if gravidity≥3, aOR = 1.5, 95% CI: [1.1-2.2]; if gravidity = 2, aOR = 1.0, 95% CI: [0.7-1.4]). Work characteristics and socioeconomic status were not independently associated with CMV seropositivity. In this cohort of pregnant women, a geographic origin of Metropolitan France and a low gravidity were predictive factors for CMV low seropositivity. Such women are therefore the likely target population for prevention of CMV infection during pregnancy in France.

  14. Predictive Factors of Cytomegalovirus Seropositivity among Pregnant Women in Paris, France

    PubMed Central

    N’Diaye, Dieynaba S.; Yazdanpanah, Yazdan; Krivine, Anne; Andrieu, Thibaut; Rozenberg, Flore; Picone, Olivier; Tsatsaris, Vassilis; Goffinet, François; Launay, Odile

    2014-01-01

    Background Cytomegalovirus (CMV) is the most frequent cause of congenital infection. The objective of this study was to evaluate predictive factors for CMV seronegativity in a cohort of pregnant women in Paris, France. Methods Pregnant women enrolled in a prospective cohort during the 2009 A/H1N1 pandemic were tested for CMV IgG antibodies. Variables collected were age, geographic origin, lifestyle, work characteristics, socioeconomic status, gravidity, parity and number of children at home. A multivariate logistic regression model was used to identify independent predictive factors for CMV seropositivity. Results Among the 826 women enrolled, 389 (47.1%) were primiparous, and 552 (67.1%) had Metropolitan France as a geographic origin. Out of these, 355 (i.e. 57.0%, 95% confidence interval (CI): [53.6%–60.4%]) were CMV seropositive: 43.7% (95% CI:[39.5%–47.9%]) in those whose geographic origin was Metropolitan France and 84.1% in those with other origins (95% CI:[79.2%–88.3%]). Determinants associated with CMV seropositivity in a multivariate logistic regression model were: (i) geographic origin (p<0.001(compared with Metropolitan France, geographic origins of Africa adjusted odds ratio (aOR) 21.2, 95% CI:[9.7–46.5], French overseas departments and territories and other origin, aOR 7.5, 95% CI:[3.9–14.6], and Europe or Asia, aOR 2.2, 95% CI: [1.3–3.7]); and (ii) gravidity (p = 0.019), (compared with gravidity = 1, if gravidity≥3, aOR = 1.5, 95% CI: [1.1–2.2]; if gravidity = 2, aOR = 1.0, 95% CI: [0.7–1.4]). Work characteristics and socioeconomic status were not independently associated with CMV seropositivity. Conclusions In this cohort of pregnant women, a geographic origin of Metropolitan France and a low gravidity were predictive factors for CMV low seropositivity. Such women are therefore the likely target population for prevention of CMV infection during pregnancy in France. PMID:24587077

  15. GOSPEL: prospective survey of gout in France. Part I: design and patient characteristics (n = 1003).

    PubMed

    Lioté, Frédéric; Lancrenon, Sylvie; Lanz, Sabine; Guggenbuhl, Pascal; Lambert, Charles; Saraux, Alain; Chiarelli, Pierre; Delva, Catherine; Aubert, Jean-Pierre; Ea, Hang-Korng

    2012-10-01

    To assess diagnoses and management of acute and chronic gout in primary care and rheumatology settings relative to 2006 European League Against Rheumatism (EULAR) gout recommendations. Secondary objectives were to describe patient demographics, clinical features, lifestyle modifications, and short- and mid-term outcomes. Prospective, cross-sectional, descriptive survey of patients with chronic gout, acute gout, or suspected gout, included by randomly selected general practitioners (GPs, n = 398) and rheumatologists (n = 109) between October 2008 and September 2009, in France. At the first visit, a structured questionnaire was completed. Each patient completed self-questionnaires at the first visit and 3 to 6 months later. We included 1003 patients, including 879 (87.6%) males (mean age, 61.6 ± 11.4 years; 28.1% obese) and 124 (12.4%) females (70.2 ± 11.9 years; 33.1% obese). Mean disease duration was 8.0 ± 8.3 years and mean time since hyperuricemia diagnosis 8.2 ± 8.4 years. Mean annual number of flares was 1.9 ± 1.5. ACR criteria for gout were met in 855 pts. Gout was acute in 487 (48.6%) patients and chronic in 241 (24.4%). Tophi (19.4% of patients) were associated with disease duration but not gender or chronic kidney disease (CKD). The main co-morbidities were hypertension (53.8%), dyslipidemia (47.2%), and hyperglycemia/diabetes mellitus (15.0%). CKD 3-5 was present in 43% of patients but was identified by physicians in only 5.2%. CKD severity was significantly associated with age, gender, hypertension, and diuretic use. This cohort will prove valuable for addressing the concordance with EULAR recommendations and for future studies of gout in everyday practice, most notably regarding metabolic syndrome, other co-morbidities, and identification of difficult-to-treat patients. Copyright © 2012 Société française de rhumatologie. Published by Elsevier SAS. All rights reserved.

  16. Effect of Vacuum-Sintering Temperature on Magnetic and Mechanical Properties of TiC-TiN-Ni-Mo-C Cermets

    NASA Astrophysics Data System (ADS)

    Zhang, Man; Yang, Qingqing; Xiong, Weihao; Zhou, Shiquan; Wang, Shengqing; Luo, Haifeng; Ruan, Linji

    2018-05-01

    The effect of vacuum-sintering temperature (T vs ), ranging from 1390 °C to 1470 °C, on magnetic and mechanical properties of TiC-10TiN-30Ni-6Mo-4C (mol pct) cermet was investigated in the present article. Room-temperature (RT) magnetization and maximum susceptibility decreased with increasing T vs up to 1450 °C, and then increased. This was mainly attributed to the fact that Ti content in the Ni-based binder phase increased with increasing T vs up to 1450 °C, suppressing ferromagnetism of the Ni matrix. RT ferromagnetism disappeared at T vs ≥ 1430 °C. Transverse rupture strength (TRS) reached a peak value at T vs = 1430 °C, and hardness did not significantly vary with T vs .

  17. France Without NATO

    DTIC Science & Technology

    1966-04-08

    and unstable France . Two decades of European peace and prosperity are causing the French to reevaluate the threat from the East and to question the...continued need for alliances in which France is not the dominate power. The French attacks on the North Atlantic Treaty Organization and the...distracted or compromised in his belief of French greatness, stands the "man who is France ," President Charles de Gaulle. France has gained strength

  18. Sources and behavior of perchlorate ions (ClO4-) in chalk aquifer of Champagne-Ardenne, France: preliminary results

    NASA Astrophysics Data System (ADS)

    Cao, Feifei; Jaunat, Jessy; Ollivier, Patrick; Cancès, Benjamin; Morvan, Xavier; Hubé, Daniel; Devos, Alain; Devau, Nicolas; Barbin, Vincent; Pannet, Pierre

    2018-06-01

    Perchlorate (ClO4-) is an environmental contaminant of growing concern due to its potential human health effects and widespread occurrence in surface water and groundwater. Analyses carried out in France have highlighted the presence of ClO4- in drinking water of Champagne-Ardenne (NW of France), with two potential sources suspected: a military source related to the First World War and an agricultural source related to the past use of Chilean nitrates. To determine the sources of ClO4- in groundwater, major and trace elements, 2H and 18O, ClO3- and ClO4- ions and a list of 39 explosives were analyzed from 35 surface water and groundwater sampling points in the east of the city of Reims. ClO4- ions were found in almost all sampling points (32 out of 35) with a max value of 33 µg L-1. ClO4- concentrations were highest in groundwater ranging from 0.7 to 33 µg L-1 (average value of about 6.2 µg L-1) against from < 0.5 to 10.2 µg L-1 in surface water (average value of about 2.7 µg L-1). Most of the water samples showing high ClO4- levels (> 4 µg L-1) were collected near a military camp, where huge quantities of ammunitions have been used, stored and destroyed during and after the First World War.

  19. 4,4\\'-Methylene bis(N,N\\'-dimethyl)aniline

    Integrated Risk Information System (IRIS)

    4,4 ' - Methylene bis ( N , N ' - dimethyl ) aniline ; CASRN 101 - 61 - 1 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Haz

  20. An integrative risk assessment approach for persistent chemicals: a case study on dioxins, furans and dioxin-like PCBs in France.

    PubMed

    Béchaux, Camille; Zeilmaker, Marco; Merlo, Mathilde; Bokkers, Bas; Crépet, Amélie

    2014-10-01

    For persistent chemicals slowly eliminated from the body, the accumulated concentration (body burden), rather than the daily exposure, is considered the proper starting point for the risk assessment. This work introduces an integrative approach for persistent chemical risk assessment by means of a dynamic body burden approach. To reach this goal a Kinetic Dietary Exposure Model (KDEM) was extended with the long term time trend in the exposure (historic exposure) and the comparison of bioaccumulation with body burden references for toxicity. The usefulness of the model was illustrated on the dietary exposure to PolyChlorinatedDibenzo-p-Dioxins (PCDDs), PolyChlorinatedDibenzoFurans (PCDFs) and PolyChlorinated Biphenyls (PCBs) in France. Firstly the dietary exposure to these compounds was determined in 2009 and combined with its long term time trend. In order to take differences between the kinetics of PCDD/F and dl-PCBs into account, three groups of congeners were considered i.e. PCDD/Fs, PCB 126 and remaining dl-PCBs. The body burden was compared with reference body burdens corresponding to reproductive, hepatic and thyroid toxicity. In the case of thyroid toxicity this comparison indicated that in 2009 the probability of the body burden to exceed its reference ranged from 2.8% (95% CI: 1.5-4.9%) up to 3.9% (95% CI: 2.7-7.1%) (18-29 vs. 60-79year olds). Notwithstanding the decreasing long-term time trend of the dietary dioxin exposure in France, this probability still is expected to be 1.5% (95% CI: 0.3-2.5%) in 2030 in 60-79 olds. In the case of reproductive toxicity the probability of the 2009 body burden to exceed its reference ranged from 3.1% (95% CI: 1.4-5.0%) (18-29year olds) to 3.5% (95% CI: 2.2-5.2%) (30-44year olds). In 2030 this probability is negligible in 18-29year olds, however small though significant in 30-44year olds (0.7%, 95% CI: 0-1.6%). In the case of hepatic toxicity the probability in 2009 even in 60-79year olds already was negligible. In

  1. New Insights into the Geographic Distribution of Mycobacterium leprae SNP Genotypes Determined for Isolates from Leprosy Cases Diagnosed in Metropolitan France and French Territories.

    PubMed

    Reibel, Florence; Chauffour, Aurélie; Brossier, Florence; Jarlier, Vincent; Cambau, Emmanuelle; Aubry, Alexandra

    2015-01-01

    Between 20 and 30 bacteriologically confirmed cases of leprosy are diagnosed each year at the French National Reference Center for mycobacteria. Patients are mainly immigrants from various endemic countries or living in French overseas territories. We aimed at expanding data regarding the geographical distribution of the SNP genotypes of the M. leprae isolates from these patients. Skin biopsies were obtained from 71 leprosy patients diagnosed between January 2009 and December 2013. Data regarding age, sex and place of birth and residence were also collected. Diagnosis of leprosy was confirmed by microscopic detection of acid-fast bacilli and/or amplification by PCR of the M. leprae-specific RLEP region. Single nucleotide polymorphisms (SNP), present in the M. leprae genome at positions 14 676, 1 642 875 and 2 935 685, were determined with an efficiency of 94% (67/71). Almost all patients were from countries other than France where leprosy is still prevalent (n = 31) or from French overseas territories (n = 36) where leprosy is not totally eradicated, while only a minority (n = 4) was born in metropolitan France but have lived in other countries. SNP type 1 was predominant (n = 33), followed by type 3 (n = 17), type 4 (n = 11) and type 2 (n = 6). SNP types were concordant with those previously reported as prevalent in the patients' countries of birth. SNP types found in patients born in countries other than France (Comoros, Haiti, Benin, Congo, Sri Lanka) and French overseas territories (French Polynesia, Mayotte and La Réunion) not covered by previous work correlated well with geographical location and history of human settlements. The phylogenic analysis of M. leprae strains isolated in France strongly suggests that French leprosy cases are caused by SNP types that are (a) concordant with the geographic origin or residence of the patients (non-French countries, French overseas territories, metropolitan France) or (b) more likely random in regions where diverse

  2. New Insights into the Geographic Distribution of Mycobacterium leprae SNP Genotypes Determined for Isolates from Leprosy Cases Diagnosed in Metropolitan France and French Territories

    PubMed Central

    Reibel, Florence; Chauffour, Aurélie; Brossier, Florence; Jarlier, Vincent; Cambau, Emmanuelle; Aubry, Alexandra

    2015-01-01

    Background Between 20 and 30 bacteriologically confirmed cases of leprosy are diagnosed each year at the French National Reference Center for mycobacteria. Patients are mainly immigrants from various endemic countries or living in French overseas territories. We aimed at expanding data regarding the geographical distribution of the SNP genotypes of the M. leprae isolates from these patients. Methodology/Principal findings Skin biopsies were obtained from 71 leprosy patients diagnosed between January 2009 and December 2013. Data regarding age, sex and place of birth and residence were also collected. Diagnosis of leprosy was confirmed by microscopic detection of acid-fast bacilli and/or amplification by PCR of the M. leprae-specific RLEP region. Single nucleotide polymorphisms (SNP), present in the M. leprae genome at positions 14 676, 1 642 875 and 2 935 685, were determined with an efficiency of 94% (67/71). Almost all patients were from countries other than France where leprosy is still prevalent (n = 31) or from French overseas territories (n = 36) where leprosy is not totally eradicated, while only a minority (n = 4) was born in metropolitan France but have lived in other countries. SNP type 1 was predominant (n = 33), followed by type 3 (n = 17), type 4 (n = 11) and type 2 (n = 6). SNP types were concordant with those previously reported as prevalent in the patients’ countries of birth. SNP types found in patients born in countries other than France (Comoros, Haiti, Benin, Congo, Sri Lanka) and French overseas territories (French Polynesia, Mayotte and La Réunion) not covered by previous work correlated well with geographical location and history of human settlements. Conclusions/Significance The phylogenic analysis of M. leprae strains isolated in France strongly suggests that French leprosy cases are caused by SNP types that are (a) concordant with the geographic origin or residence of the patients (non-French countries, French overseas territories

  3. Effect of NaF, SnF(2), and TiF(4) Toothpastes on Bovine Enamel and Dentin Erosion-Abrasion In Vitro.

    PubMed

    Comar, Lívia Picchi; Gomes, Marina Franciscon; Ito, Naiana; Salomão, Priscila Aranda; Grizzo, Larissa Tercília; Magalhães, Ana Carolina

    2012-01-01

    The aim of this study was to compare the effect of toothpastes containing TiF(4), NaF, and SnF(2) on tooth erosion-abrasion. Bovine enamel and dentin specimens were distributed into 10 groups (n = 12): experimental placebo toothpaste (no F); NaF (1450 ppm F); TiF(4) (1450 ppm F); SnF(2) (1450 ppm F); SnF(2) (1100 ppm F) + NaF (350 ppm F); TiF(4) (1100 ppm F) + NaF (350 ppm F); commercial toothpaste Pro-Health (SnF(2)-1100 ppm F + NaF-350 ppm F, Oral B); commercial toothpaste Crest (NaF-1.500 ppm F, Procter & Gamble); abrasion without toothpaste and only erosion. The erosion was performed 4 × 90 s/day (Sprite Zero). The toothpastes' slurries were applied and the specimens abraded using an electric toothbrush 2 × 15 s/day. Between the erosive and abrasive challenges, the specimens remained in artificial saliva. After 7 days, the tooth wear was evaluated using contact profilometry (μm). The experimental toothpastes with NaF, TiF(4), SnF(2), and Pro-Health showed a significant reduction in enamel wear (between 42% and 54%). Pro-Health also significantly reduced the dentin wear. The toothpastes with SnF(2)/NaF and TiF(4)/NaF showed the best results in the reduction of enamel wear (62-70%) as well as TiF(4), SnF(2), SnF(2)/NaF, and TiF(4)/NaF for dentin wear (64-79%) (P < 0.05). Therefore, the experimental toothpastes containing both conventional and metal fluoride seem to be promising in reducing tooth wear.

  4. The Spirit of France

    DTIC Science & Technology

    1994-01-01

    seemed to boost self esteem amongst the French , giving France a greater sense of dignity. Charles de Gaulle sought grandeur to unite France and give...overshadowed by the US, UK and Russia. The war had left France with little influence in Europe and had psychologically and morally weakened the French ... France as a way to increase the influence base of the French state. Influence, either perceived or real, meant power. Power represented independence

  5. 75 FR 48615 - Airworthiness Directives; Eurocopter France (ECF) Model AS350B3 and EC130 B4 Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-11

    .... Related Service Information ECF has issued Alert Service Bulletin (ASB) No. 05.00.61 for the Model AS350B3... Airworthiness Directives; Eurocopter France (ECF) Model AS350B3 and EC130 B4 Helicopters AGENCY: Federal... adopt a new airworthiness directive (AD) for the specified ECF model helicopters. This proposed AD...

  6. Satellite remote sensing of hailstorms in France

    NASA Astrophysics Data System (ADS)

    Melcón, Pablo; Merino, Andrés; Sánchez, José Luis; López, Laura; Hermida, Lucía

    2016-12-01

    Hailstorms are meteorological phenomena of great interest to the scientific community, owing to their socioeconomic impact, which is mainly on agricultural production. With its global coverage and high spatial and temporal resolution, satellite remote sensing can contribute to monitoring of such events through the development of appropriate techniques. This paper presents an extensive validation in the south of France of a hail detection tool (HDT) developed for the Middle Ebro Valley (MEV). The HDT is based on consecutive application of two filters, a convection mask (CM) and hail mask (HM), using spectral channels of the Meteosat Second Generation (MSG) satellite. The south of France is an ideal area for studying hailstorms, because there is a robust database of hail falls recorded by an extensive network of hailpads managed by the Association Nationale d'Etude et de Lutte contre les Fleáux Atmosphériques (ANELFA). The results show noticeably poorer performance of the HDT in France relative to that in the MEV, with probability of detection (POD) 60.4% and false alarm rate (FAR) 26.6%. For this reason, a new tool to suit the characteristics of hailstorms in France has been developed. The France Hail Detection Tool (FHDT) was developed using logistic regression from channels of the Spinning Enhanced Visible and Infrared Imager (SEVIRI) sensor of the MSG. The FHDT was validated, resulting in POD 69.3% and FAR 15.4%, thus improving hail detection in the study area as compared with the previous tool. The new tool was tested in a case study with satisfactory results, supporting its future practical application.

  7. France.

    PubMed

    1987-09-01

    In 1986, France had a population of 55,493,000, with an annual growth rate of 0.4%. The infant mortality rate stood at 8.2/1000. Of the work force of 23.8 million, 8.3% were engaged in agriculture, 45.2% were in the industry and commerce sector, and 46.5% were engaged in services. The unemployment rate stood at 10.7%. The country's gross domestic product (GDP) was US$724 billion in 1986, with an average annual growth rate of 2.0%, and per capita income averaged $13,046. France has substantial agricultural resources, a diversified modern industrial system, and a highly skilled labor force. Following the return of a socialist majority in government in 1981, several large manufacturing firms were nationalized along with much of the commercial banking sector. Initial socialist policies were stimulative, relying partly on income redistribution and partly on increased government spending. However, the resultant increase in import demand was not offset by an increased demand French exports. In 1983, an economic stabilization plan of reductions in the budget deficit, involving spending cuts, increased taxes, and tighter monetary and credit policies, was successfully implemented. Although current economic policies should promote stronger growth over the medium to long term, trade competitiveness remains weak and high unemployment is a major social problem.

  8. [Low level of physical fitness in Spanish adolescents. Relevance for future cardiovascular health (AVENA study)].

    PubMed

    Ortega, Francisco B; Ruiz, Jonatan R; Castillo, Manuel J; Moreno, Luis A; González-Gross, Marcela; Wärnberg, Julia; Gutiérrez, Angel

    2005-08-01

    Several studies have demonstrated that physical fitness in childhood and adolescence is related to cardiovascular risk in adulthood. Current data on the physical fitness of Spanish adolescents are not available. Therefore, the aims of this study were: a) to assess the physical fitness of Spanish adolescents and establish reference values for use in health and educational settings as indicators of cardiovascular health, and b) to determine the percentage of Spanish adolescents below the minimum level of aerobic fitness needed to guarantee future cardiovascular health. The modified EUROFIT battery of tests was used to assess physical fitness in a representative sample of Spanish adolescents (n=2859; 1357 boys and 1502 girls) taking part in the AVENA (Alimentación y Valoración del Estado Nutricional de los Adolescentes) study. Standard parameters for the physical condition of Spanish adolescents are reported in this study. The 5th percentile for maximum aerobic capacity (Course Navette test) ranged from 2.0-3.3 palier in boys and from 1.4-1.9 palier in girls. The findings indicate that, on the basis of aerobic fitness, approximately 20% of Spanish adolescents have an increased risk of future cardiovascular disease. This subgroup also performed poorly in all other tests of physical fitness used. The results reported in this study enable the level of physical fitness in adolescents to be interpreted as an indicator of future cardiovascular health. They also indicate that the physical fitness of Spanish adolescents must be improved to help protect against cardiovascular disease in adulthood.

  9. 40 CFR 721.1085 - Benzenamine,4,4′-methylenebis[N-ethyl-N-methyl-.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 31 2011-07-01 2011-07-01 false Benzenamine,4,4â²-methylenebis[N-ethyl-N-methyl-. 721.1085 Section 721.1085 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Specific Chemical Substances § 721.1085 Benzenamine,4,4′-methylenebis[N-ethyl-N-methyl-. (a) Chemical...

  10. 40 CFR 721.1085 - Benzenamine,4,4′-methylenebis[N-ethyl-N-methyl-.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Benzenamine,4,4â²-methylenebis[N-ethyl-N-methyl-. 721.1085 Section 721.1085 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Specific Chemical Substances § 721.1085 Benzenamine,4,4′-methylenebis[N-ethyl-N-methyl-. (a) Chemical...

  11. Ancient mitochondrial DNA and ancestry of Paquimé inhabitants, Casas Grandes (A.D. 1200-1450).

    PubMed

    Morales-Arce, Ana Y; Snow, Meradeth H; Kelley, Jane H; Anne Katzenberg, M

    2017-07-01

    The Casas Grandes (Paquimé) culture, located in the Northwest of Chihuahua, Mexico reached its apogee during the Medio Period (A.D. 1200-1450). Paquimé was abandoned by the end of the Medio Period (A.D. 1450), and the ancestry of its inhabitants remains unsolved. Some authors suggest that waves of Mesoamerican immigrants, possibly merchants, stimulated Paquimé's development during the Medio Period. Archaeological evidence suggests possible ties to groups that inhabited the Southwestern US cultures. This study uses ancient DNA analysis from fourteen samples to estimate genetic affinities of ancient Paquimé inhabitants. DNA was extracted from 14 dental ancient samples from Paquimé. PCR and Sanger sequencing were used to obtain mitochondrial control region sequences. Networks, PCoA, and Nei genetic distances were estimated to compare Paquimé haplotypes against available past haplotypes data from Southwestern and Mesoamerican groups. Haplogroups were characterized for 11 of the samples, and the results revealed the presence of four distinct Amerindian mitochondrial lineages: B (n = 5; 45%), A (n = 3; 27%), C (n = 2; 18%) and D (n = 1; 10%). Statistical analysis of the haplotypes, haplogroup frequencies, and Nei genetic distances showed close affinity of Paquimé with Mimbres. Although our results provide strong evidence of genetic affinities between Paquimé and Mimbres, with the majority of haplotypes shared or derived from ancient Southwest populations, the causes of cultural development at Paquimé still remain a question. These preliminary results provide evidence in support of other bioarchaeological studies, which have shown close biological affinities between Paquimé and Mimbres, a Puebloan culture, in the Southwestern US. © 2017 Wiley Periodicals, Inc.

  12. Dietary habits in New France during the 17th and 18th centuries: An isotopic perspective.

    PubMed

    Vigeant, J; Ribot, I; Hélie, J-F

    2017-03-01

    Little attention has been given, so far, to the early colonial diet in New France from an isotopic perspective. Historical records that compare France to New France suggest a shift toward a more diverse diet, including a higher protein intake due to an improvement in living conditions in the New World, despite the retention of ancestral dietary habits. This hypothesis will be explored here. Stable carbon (organic and mineral) and nitrogen isotopes were measured on 43 individuals from Notre Dame cemetery (first Catholic parish church cemetery in Montreal, 1683-1803) as well as 13 French compatriots from La Rochelle, France (Protestant Hospital Cemetery, 1765-1792). Intragroup variation (age at death, sex, and/or burial location) was investigated and compared to compiled data from various northeastern North American sites (N = 99). The Notre Dame sample means are as follows: -19.6‰ versus VPDB for δ 13 C collagen , -12.22‰ versus VPDB for δ 13 C carbonate , and 11.5‰ versus AIR for δ 15 N. They are significantly lower than both La Rochelle (-18.4‰, -11.67‰, and 12.7‰, respectively, p ≤ .005) and the northeastern North American groups used for this comparison (p = .000). The isotopic values obtained from Notre Dame cemetery suggest that the diet was mainly based on C 3 resources with limited C 4 resources. Although different from all comparable contemporary sites, colonial Montreal's diet remains most similar to La Rochelle, France. This study agrees with historians who have suggested that French dietary traditions seem to have been retained among the early colonial inhabitants of Montreal. © 2016 Wiley Periodicals, Inc.

  13. [Primary care in France].

    PubMed

    Sánchez-Sagrado, T

    2016-01-01

    The poor planning of health care professionals in Spain has led to an exodus of doctors leaving the country. France is one of the chosen countries for Spanish doctors to develop their professional career. The French health care system belongs to the Bismarck model. In this model, health care system is financed jointly by workers and employers through payroll deduction. The right to health care is linked to the job, and provision of services is done by sickness-funds controlled by the Government. Primary care in France is quite different from Spanish primary care. General practitioners are independent workers who have the right to set up a practice anywhere in France. This lack of regulation has generated a great problem of "medical desertification" with problems of health care access and inequalities in health. French doctors do not want to work in rural areas or outside cities because "they are not value for money". Medical salary is linked to professional activity. The role of doctors is to give punctual care. Team work team does not exist, and coordination between primary and secondary care is lacking. Access to diagnostic tests, hospitals and specialists is unlimited. Duplicity of services, adverse events and inefficiencies are the norm. Patients can freely choose their doctor, and they have a co-payment for visits and hospital care settings. Two years training is required to become a general practitioner. After that, continuing medical education is compulsory, but it is not regulated. Although the French medical Health System was named by the WHO in 2000 as the best health care system in the world, is it not that good. While primary care in Spain has room for improvement, there is a long way for France to be like Spain. Copyright © 2015 Sociedad Española de Médicos de Atención Primaria (SEMERGEN). Publicado por Elsevier España, S.L.U. All rights reserved.

  14. France and European Security

    DTIC Science & Technology

    1986-04-01

    block number) In the 1960s, French defense policy emphasized the protection of French territory rather than the collective security of France and her... France and her European allies. This began to change in the late 1970s. The French contribution to European security is now a matter of considerable...independence. He interpreted independence in a specific manner. Although France would maintain ties and commitments to its allies, the French government

  15. 78 FR 40045 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-03

    ... directive (AD) for Eurocopter France (Eurocopter) Model AS350B, BA, B1, B2, B3, D, AS355E, F, F1, F2, and N... comments that we receive, as well as a report summarizing each substantive public contact with FAA... Eurocopter Model AS350B, BA, BB, B1, B2, B3, D, AS355 E, F, F1, F2, and N helicopters delivered before...

  16. The Evolution of Minehunting in France (L’Evolution de la Chasse aux Mines en France),

    DTIC Science & Technology

    1983-07-13

    The Necessity of Minehunting in France And why are the French , Ohl such a small number of experts, interested in minehunting? The coasts of France are...AD-A132 532 THE EVOLUTION OF MINEHUNTING IN FRANCE IL’EVOLUTION DE I/1 LA CHASSE AUX MINES EN FRANCE )(U) NAVAL INTELLIGENCE SUPPORT CENTER WASHINGTON...MINEHUNTING IN FRANCE AUTHOR: DE DREZIGUE TRANSLATEO gY: LCDR ROBERT AUGELLI, USNR-R NISC TRANSLATION UNIT 0166 eei o DTIC MI’S OR&I DfIC T ELECTE Ja~tinoati

  17. 77 FR 58218 - BNSF Railway Company-Abandonment Exemption-in McKinley County, N.M.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-19

    ... DEPARTMENT OF TRANSPORTATION Surface Transportation Board [Docket No. AB 6 (Sub-No. 485X)] BNSF Railway Company--Abandonment Exemption--in McKinley County, N.M. BNSF Railway Company (BNSF) has filed a... rail line located between milepost 14.50 and milepost 19.61, north of Defiance, in McKinley County, N.M...

  18. France: Factors Shaping Foreign Policy, and Issues in U.S.-French Relations

    DTIC Science & Technology

    2009-05-20

    TYPE 3. DATES COVERED 00-00-2009 to 00-00-2009 4. TITLE AND SUBTITLE France : Factors Shaping Foreign Policy, and Issues in U.S.- French ...Z39-18 France : Factors Shaping Foreign Policy, and Issues in U.S.- French Relations Congressional Research Service Summary The factors that shape... French foreign policy have changed since the end of the Cold War. The perspectives of France and the United States have diverged in some cases. More

  19. Measures to control an imported case of canine rabies in France.

    PubMed

    2006-01-01

    France has been free from terrestrial rabies since 2001. On 21 August 2004, a female dog aged 4 months died in Gironde (south-west France), after experiencing clinical symptoms suggestive of rabies for 3 days. On 26 August, a diagnosis of rabies was confirmed by the Pasteur Institute. This paper describes the measures that were taken to manage the risks to human and animal health, and analyses the alert raised in France as a result of this imported case of rabies, the third such case in 2004.

  20. Germany, France and NATO

    DTIC Science & Technology

    1994-10-17

    the Alliance. Ii. France and NATO. " The French position on NAI 0 has evolved since 1990. Rance has moved toward closer military cooperation with...NATO as demonstrated, for example, by the subcrdination c! French troops in the EUROCORPS io SACFUR when a crisis demands it, " Yet France has also...future. Greater cooperation may develop between France and the United Kingdom, particularly in nuclear matters, as indicated in the French White

  1. Divergent genetic evolution of hemagglutinin in influenza A H1N1 and A H1N2 subtypes isolated in the south-France since the winter of 2001-2002.

    PubMed

    Al Faress, Shaker; Cartet, Gaëlle; Ferraris, Olivier; Norder, Helene; Valette, Martine; Lina, Bruno

    2005-07-01

    Influenza A viruses are divided into subtypes based on their hemagglutinin (H1 to H15) and neuraminidase (N1 to N9) glycoproteins. Of these, three A subtypes H1N1, H3N2 and H1N2 circulate in the human population. Influenza A viruses display a high antigenic variability called "antigenic drift" which allows the virus to escape antibody neutralization. Evaluate the mutations apparition that might predict a divergent antigenic evolution of hemagglutinin in influenza A H1N1 and A H1N2 viruses. During the three winters of 2001-2002 to 2003-2004, 58 A H1N1 and 23 A H1N2 subtypes have been isolated from patients with influenza-like illness in the south of France. The HA1 region was analyzed by RT-PCR and subsequently sequenced to compare the HA1 genetic evolution of influenza A H1N1 and A H1N2 subtypes. Our results showed that 28 amino acid substitutions have accumulated in the HA1 region since the circulation of A/New Caledonia/20/99-like viruses in France. Of these, fifteen were located in four antigenic sites (B, C, D and E). Six of them were observed only in the A H1N2 isolates, six only in the A H1N1 isolates and three in both subtypes. Furthermore, nine of twenty two A H1N2 isolates from the winter of 2002-2003 shared a T90A amino acid change which has not been observed in any A H1N1 isolate; resulting in the introduction of a new glycosylation site close to the antigenic site E. This might mask some antigenic E determinants and therefore, modify the A H1N2 antigenicity. The divergent genetic evolution of hemagglutinin may ultimately lead to a significant different antigenicity between A H1N1 and A H1N2 subtypes that would require the introduction of a new subtype in the vaccine batches.

  2. Theoretical and Experimental Studies of N,N-Dimethyl-N'-Picryl-4,4'-Stilbenediamine.

    PubMed

    Papper, Vladislav; Wu, Yuanyuan; Kharlanov, Vladimir; Sukharaharja, Ayrine; Steele, Terry W J; Marks, Robert S

    2018-01-01

    N,N-dimethyl-N'-picryl-4,4'-stilbenediamine (DMPSDA) was prepared, purified and crystallised in a form of black lustrous crystals, and its absorption and fluorescence spectra were recorded in cyclohexane, acetonitrile and dimethyl sulfoxide. Non-emissive intramolecular charge transfer state (ICT) was clearly observed in this molecule in all three solvents. Theoretical calculations demonstrating a betaine electronic structure of the trinitrophenyl group in the ground state of the molecule and a charge transfer nature of the long wavelength transition S 0  → S 1 supported the experimental observations of the ICT formation in the molecule.

  3. Public media communications about H1N1, risk perceptions and immunization behaviours: A Quebec-France comparison.

    PubMed

    Rousseau, Cécile; Moreau, Nicolas; Dumas, Marie-Pier; Bost, Ida; Lefebvre, Sylvie; Atlani-Duault, Laëtitia

    2015-02-01

    During the H1N1 pandemic, governments tailored their communications plans in order to influence risk perception and promote public compliance with the public health plan measures. Considering the volume and the content of calls to flu information centres as indicators of the public risk perception, this mixed method study compares the relation between public communications, risk perception and immunization behaviour in Quebec and France. Results suggest that advocating for clear information and coordination between health authorities and the media promotes adherence to preventive behaviour. However, over-exaggerating the risks and minimizing the population's agency may undermine health authority credibility. © The Author(s) 2013.

  4. Multiple sclerosis in North African migrants to France.

    PubMed

    Kurtzke, J F; Delasnerie-Lauprêtre, N; Wallin, M T

    1998-11-01

    Among some 7500 respondents with known place of birth who had completed a nationwide questionnaire survey for multiple sclerosis (MS) in France in 1986, there were 260 born in former French North Africa (Algeria, Morocco, Tunisia). They had migrated to France between 1923 and 1986, but 66% came between 1956 and 1964. Two-thirds were from Algeria, where virtually the entire European population had emigrated in 1962 at the end of the Algerian war for independence. The migrants were younger at prevalence day (mean 43.4 years) and at onset (29.4 years) than the French-born MS (46.6; 31.3 years). Eight migrants lacked age information. The 225 migrants with onset more than 1 year after immigration presumably acquired their MS in France. They provided an age adjusted (US 1960) MS prevalence rate 1.54 times that for all France. If the latter is taken at 50 per 100,000 population their estimated adjusted rate is 76.8 with 95% confidence interval of 67.1 to 87.5. The other 27 with presumed acquisition in North Africa gave an estimated adjusted prevalence of 16.6 per 100,000 (95% CI 10.9-24.1). For those migrants with acquisition in France there was a mean interval of 13 years between immigration or age 11 and clinical onset, with a minimum of 3 years. This series provides further support for the theses: 1) that MS is primarily an environmental disease acquired after childhood; 2) that acquisition requires prolonged or repeated exposure (here 3 years for these medium-to-high MS risk migrants) followed by a prolonged latent or incubation period between acquisition and symptom onset (here 10 years); and 3) that this disease is most likely a widespread but unknown persistent infection which results in clinical MS in only a small proportion of those affected.

  5. The contribution of faint AGNs to the ionizing background at z 4

    NASA Astrophysics Data System (ADS)

    Grazian, A.; Giallongo, E.; Boutsia, K.; Cristiani, S.; Vanzella, E.; Scarlata, C.; Santini, P.; Pentericci, L.; Merlin, E.; Menci, N.; Fontanot, F.; Fontana, A.; Fiore, F.; Civano, F.; Castellano, M.; Brusa, M.; Bonchi, A.; Carini, R.; Cusano, F.; Faccini, M.; Garilli, B.; Marchetti, A.; Rossi, A.; Speziali, R.

    2018-05-01

    Context. Finding the sources responsible for the hydrogen reionization is one of the most pressing issues in observational cosmology. Bright quasi-stellar objects (QSOs) are known to ionize their surrounding neighborhood, but they are too few to ensure the required HI ionizing background. A significant contribution by faint active galactic nuclei (AGNs), however, could solve the problem, as recently advocated on the basis of a relatively large space density of faint active nuclei at z > 4. Aims: This work is part of a long-term project aimed at measuring the Lyman Continuum escape fraction for a large sample of AGNs at z 4 down to an absolute magnitude of M1450 -23. We have carried out an exploratory spectroscopic program to measure the HI ionizing emission of 16 faint AGNs spanning a broad U - I color interval, with I 21-23, and 3.6 < z < 4.2. These AGNs are three magnitudes fainter than the typical SDSS QSOs (M1450 ≲-26) which are known to ionize their surrounding IGM at z ≳ 4. Methods: We acquired deep spectra of these faint AGNs with spectrographs available at the VLT, LBT, and Magellan telescopes, that is, FORS2, MODS1-2, and LDSS3, respectively. The emission in the Lyman Continuum region, close to 900 Å rest frame, has been detected with a signal to noise ratio of 10-120 for all 16 AGNs. The flux ratio between the 900 Å rest-frame region and 930 Å provides a robust estimate of the escape fraction of HI ionizing photons. Results: We have found that the Lyman Continuum escape fraction is between 44 and 100% for all the observed faint AGNs, with a mean value of 74% at 3.6 < z < 4.2 and - 25.1 ≲ M1450 ≲-23.3, in agreement with the value found in the literature for much brighter QSOs (M1450 ≲-26) at the same redshifts. The Lyman Continuum escape fraction of our faint AGNs does not show any dependence on the absolute luminosities or on the observed U - I colors of the objects. Assuming that the Lyman Continuum escape fraction remains close to 75% down

  6. Effect of absorption recovery in bismuth-doped silica glass at 1450 nm on soliton grouping in fiber laser

    PubMed Central

    Gumenyuk, R.; Melkumov, M. A.; Khopin, V. F.; Dianov, E. M.; Okhotnikov, O. G.

    2014-01-01

    Saturable absorption in bismuth-doped glasses was found to have a noticeable influence on soliton interaction and group formation. This phenomenon, observed in 1450 nm mode-locked bismuth-doped fiber laser, shows the distinct feature of the multiple pulse regime, which appears as a stationary pulse group whose length can be spread over the whole cavity length by variation of the pump power and polarization. Pulse positioning within the ensemble depends on the saturation fluence and the relatively fast recovery dynamics of bismuth fiber. PMID:25391808

  7. Increasing Incidence of Listeriosis in France and Other European Countries

    PubMed Central

    Hedberg, Craig; Le Monnier, Alban; de Valk, Henriette

    2008-01-01

    From 1999 through 2005, the incidence of listeriosis in France declined from 4.5 to 3.5 cases/million persons. In 2006, it increased to 4.7 cases/million persons. Extensive epidemiologic investigations of clusters in France have ruled out the occurrence of large foodborne disease outbreaks. In addition, no increase has occurred in pregnancy-associated cases or among persons <60 years of age who have no underlying disease. Increases have occurred mainly among persons >60 years of age and appear to be most pronounced for persons >70 years of age. In 8 other European countries, the incidence of listeriosis has increased, or remained relatively high, since 2000. As in France, these increases cannot be attributed to foodborne outbreaks, and no increase has been observed in pregnancy-associated cases. European countries appear to be experiencing an increased incidence of listeriosis among persons >60 years of age. The cause of this selective increased incidence is unknown. PMID:18439354

  8. Psycho-social influences on food choice in Southern France and Central England.

    PubMed

    Pettinger, C; Holdsworth, M; Gerber, M

    2004-06-01

    This study used attitudinal scales to investigate the nature of attitudes to diet and health in a northern European country (Central England) and a southern European country (Mediterranean France). Cross-sectional studies were conducted using self-administered postal questionnaires that were distributed simultaneously in April 2001 in Montpellier, France and Nottingham, England. A stratified random sample of 1000 males and 1000 females aged 18-65 years was generated from the electoral roll in each country. The final sample comprised England: n = 826 (58% male and 42% female; mean age=44 years) and France: n = 766 (42% male and 58% female; mean age=42 years). This study has demonstrated that the pleasurable and social aspects of eating, certain food quality issues, as well as health as a value were regarded as priorities by French respondents. On the other hand, English respondents reported that organic and ethical issues and convenience were important factors influencing their food choices. In conclusion, the two populations can be differentiated overall in their attitudes and beliefs to food choice.

  9. From N=4 Galilean superparticle to three-dimensional non-relativistic N=4 superfields

    NASA Astrophysics Data System (ADS)

    Fedoruk, Sergey; Ivanov, Evgeny; Lukierski, Jerzy

    2018-05-01

    We consider the general N=4 , d = 3 Galilean superalgebra with arbitrary central charges and study its dynamical realizations. Using the nonlinear realization techniques, we introduce a class of actions for N=4 three-dimensional non-relativistic superparticle, such that they are linear in the central charge Maurer-Cartan one-forms. As a prerequisite to the quantization, we analyze the phase space constraints structure of our model for various choices of the central charges. The first class constraints generate gauge transformations, involving fermionic κ-gauge transformations. The quantization of the model gives rise to the collection of free N=4 , d = 3 Galilean superfields, which can be further employed, e.g., for description of three-dimensional non-relativistic N=4 supersymmetric theories.

  10. N-2-Hydroxy-4-methoxyacetophenone- N'-4-nitrobenzoyl hydrazine: Synthesis and structural characterization

    NASA Astrophysics Data System (ADS)

    Bessy Raj, B. N.; Kurup, M. R. Prathapachandra

    2007-04-01

    A new aroyl hydrazone, N-2-hydroxy-4-methoxyacetophenone- N'-4-nitrobenzoyl hydrazine was prepared by the condensation reaction of 2-hydroxy-4-methoxyacetophenone and 4-nitrobenzoyl hydrazine. Characterization of the compound was done by elemental analysis and electronic, infrared and NMR spectral analyses. The complete structural assignment of the compound was done by NMR studies by using COSY homonuclear and HSQC heteronuclear techniques. The crystal and molecular structure was determined by single crystal X-ray diffraction studies: crystallized in the monoclinic system, space group P2 1/ n, Z = 4, a = 7.3343(9) Å, b = 20.3517(9) Å, c = 10.1375(5) Å, α = 90.00°, β = 95.735(7)° and γ = 90.00°. From the crystal structure, it is concluded that the compound exists as the keto isomer in the solid state. There is a completely extended conformation in the central part of the molecule C5 sbnd C8 dbnd N1 sbnd N2 sbnd C10 dbnd O2 with an E configuration at the double bond of the hydrazinic bridge.

  11. 10 years of surveillance of human tularaemia in France.

    PubMed

    Mailles, A; Vaillant, V

    2014-11-13

    Tularaemia has been mandatorily notifiable in France since October 2002. The surveillance aims to detect early any infection possibly due to bioterrorism and to follow up disease trends. We report the results of national surveillance from 2002 to 2012. A case is defined as a patient with clinical presentation suggestive of tularaemia and biological confirmation of infection or an epidemiological link with a biologically confirmed case. Clinical, biological and epidemiological data are collected using a standardised notification form. From 2002 to 2012, 433 cases were notified, with a median age of 49 years (range 2 to 95 years) and a male–female sex ratio of 1.8. Most frequent clinical presentations were glandular tularaemia (n=200; 46%) and ulceroglandular tularaemia (n=113; 26%). Most frequent at-risk exposures were handling hares (n=179; 41%) and outdoor leisure exposure to dust aerosols (n=217; 50%). Tick bites were reported by 82 patients (19%). Ten clusters (39 cases) were detected over the 10-year period, as well as a national outbreak during winter 2007/2008. The tularaemia surveillance system is able to detect small clusters as well as major outbreaks. Surveillance data show exposure to dust aerosols during outdoor leisure activities to be a major source of contamination in France.

  12. Populations at Risk for Alveolar Echinococcosis, France

    PubMed Central

    Piarroux, Martine; Piarroux, Renaud; Knapp, Jenny; Bardonnet, Karine; Dumortier, Jérôme; Watelet, Jérôme; Gerard, Alain; Beytout, Jean; Abergel, Armand; Bresson-Hadni, Solange

    2013-01-01

    During 1982–2007, alveolar echinococcosis (AE) was diagnosed in 407 patients in France, a country previously known to register half of all European patients. To better define high-risk groups in France, we conducted a national registry-based study to identify areas where persons were at risk and spatial clusters of cases. We interviewed 180 AE patients about their way of life and compared responses to those of 517 controls. We found that almost all AE patients lived in 22 départements in eastern and central France (relative risk 78.63, 95% CI 52.84–117.02). Classification and regression tree analysis showed that the main risk factor was living in AE-endemic areas. There, most at-risk populations lived in rural settings (odds ratio [OR] 66.67, 95% CI 6.21–464.51 for farmers and OR 6.98, 95% CI 2.88–18.25 for other persons) or gardened in nonrural settings (OR 4.30, 95% CI 1.82–10.91). These findings can help sensitization campaigns focus on specific groups. PMID:23647623

  13. Nutrition Transition and Biocultural Determinants of Obesity among Cameroonian Migrants in Urban Cameroon and France

    PubMed Central

    Cohen, Emmanuel; Amougou, Norbert; Ponty, Amandine; Loinger-Beck, Juliette; Nkuintchua, Téodyl; Monteillet, Nicolas; Bernard, Jonathan Y.; Saïd-Mohamed, Rihlat; Holdsworth, Michelle; Pasquet, Patrick

    2017-01-01

    Native of rural West Cameroon, the Bamiléké population is traditionally predisposed to obesity. Bamiléké who migrated to urban areas additionally experience the nutrition transition. We investigated the biocultural determinants of obesity in Bamiléké who migrated to urban Cameroon (Yaoundé), or urban France (Paris). We conducted qualitative interviews (n = 36; 18 men) and a quantitative survey (n = 627; 266 men) of adults using two-stage sampling strategy, to determine the association of dietary intake, physical activity and body weight norms with obesity of Bamiléké populations in these three socio-ecological areas (rural Cameroon: n = 258; urban Cameroon: n = 319; urban France: n = 50). The Bamiléké valued overweight and traditional energy-dense diets in rural and urban Cameroon. Physical activity levels were lower, consumption of processed energy-dense food was frequent and obesity levels higher in new migrants living in urban Cameroon and France. Female sex, age, duration of residence in urban areas, lower physical activity and valorisation of overweight were independently associated with obesity status. This work argues in favour of local and global health policies that account for the origin and the migration trajectories to prevent obesity in migrants. PMID:28661463

  14. Nutrition Transition and Biocultural Determinants of Obesity among Cameroonian Migrants in Urban Cameroon and France.

    PubMed

    Cohen, Emmanuel; Amougou, Norbert; Ponty, Amandine; Loinger-Beck, Juliette; Nkuintchua, Téodyl; Monteillet, Nicolas; Bernard, Jonathan Y; Saïd-Mohamed, Rihlat; Holdsworth, Michelle; Pasquet, Patrick

    2017-06-29

    Native of rural West Cameroon, the Bamiléké population is traditionally predisposed to obesity. Bamiléké who migrated to urban areas additionally experience the nutrition transition. We investigated the biocultural determinants of obesity in Bamiléké who migrated to urban Cameroon (Yaoundé), or urban France (Paris). We conducted qualitative interviews ( n = 36; 18 men) and a quantitative survey ( n = 627; 266 men) of adults using two-stage sampling strategy, to determine the association of dietary intake, physical activity and body weight norms with obesity of Bamiléké populations in these three socio-ecological areas (rural Cameroon: n = 258; urban Cameroon: n = 319; urban France: n = 50). The Bamiléké valued overweight and traditional energy-dense diets in rural and urban Cameroon. Physical activity levels were lower, consumption of processed energy-dense food was frequent and obesity levels higher in new migrants living in urban Cameroon and France. Female sex, age, duration of residence in urban areas, lower physical activity and valorisation of overweight were independently associated with obesity status. This work argues in favour of local and global health policies that account for the origin and the migration trajectories to prevent obesity in migrants.

  15. Water and beverage consumption among children aged 4-13 years in France: analyses of INCA 2 (Étude Individuelle Nationale des Consommations Alimentaires 2006-2007) data.

    PubMed

    Vieux, Florent; Maillot, Matthieu; Constant, Florence; Drewnowski, Adam

    2016-09-01

    To examine the consumption of plain water among children in France and compare total water intakes with guidelines issued by the European Food Safety Authority (EFSA). Nationally representative data were used to assess food, beverage and water consumption by sex, age group (4-8 years, 9-13 years), income-to-poverty ratio, eating occasion and location. Beverages were classified into nine groups: water (tap or bottled), milk, 100 % fruit juice, sodas, fruit drinks, hot beverages, sports drinks and flavoured waters. Total water volume in relation to energy intake (litres/kcal) was also examined. INCA 2 study (Étude Individuelle Nationale des Consommations Alimentaires 2006-2007). French children (n 835) aged 4-13 years. Total water intakes were accounted for by plain water (34 %), beverages (26 %) and food moisture (40 %). Plain water could be tap (18 %) or bottled (16 %). Older children drank more plain water than did younger children and boys drank more plain water than did girls. No socio-economic gradient for plain water consumption was observed. About 90 % of children did not meet the EFSA water intake recommendations. The daily water shortfall ranged from 367 to 594 ml/d. Water-to-energy ratio was 0·75-0·77 litres/1000 kcal (4184 kJ). Children drank milk at breakfast and plain water during lunch and dinner. Caloric beverages provided 10 % of dietary energy; consumption patterns varied by eating location. Total water intakes among young children in France were below EFSA-recommended levels. Analyses of beverage consumption patterns by eating occasion and location can help identify ways to increase water consumption among children.

  16. Floods in southwest-central Florida from hurricane Frances, September 2004

    USGS Publications Warehouse

    Kane, Richard L.

    2005-01-01

    Hurricane Frances brought heavy rainfall and widespread flooding to southwest-central Florida September 4-14, 2004. The center of Hurricane Frances made landfall on the east coast of Florida on September 5 as a category 2 hurricane on the Saffir-Simpson scale, then moved west-northwestward through central Florida before exiting Pasco County into the Gulf of Mexico on September 6 (fig. 1; National Weather Service, 2004). The hurricane moved across the Florida Peninsula generating 5 to 11 inches of rain over already saturated ground (table 1). Record flooding occurred in parts of Hardee, Hillsborough, Pasco, and Polk Counties (fig. 1). The hurricane and resulting floods caused an estimated $4-5 billion in damage to public and private property (Harrington, 2004), and 23 deaths were attributed to Hurricane Frances (National Weather Service, 2004). Several watersheds drain counties in southwest-central Florida that were affected by Hurricane Frances. De Soto, Hardee, and Polk Counties generally are drained by the Peace River system, which flows southwestward to Charlotte Harbor and the Gulf of Mexico. Hillsborough and Pasco Counties generally are drained by the Alafia, Hillsborough, Anclote, and Pithlachascotee River systems. Water in the Hillsborough and Alafia River watersheds flows west to Tampa Bay and water in the Anclote and Pithlachascotee River watersheds flows west to the Gulf of Mexico. (fig. 1, http://water.usgs.gov/pubs/fs/2005/3028/#fig1).

  17. Understanding differences in conception and abortion rates among under-20 year olds in Britain and France: Examining the contribution of social disadvantage.

    PubMed

    Scott, Rachel H; Bajos, Nathalie; Slaymaker, Emma; Wellings, Kaye; Mercer, Catherine H

    2017-01-01

    Socioeconomic status has been shown to be associated with sexual activity, contraceptive-use, pregnancy and abortion among young people. Less is known about whether the strength of the association differs for each outcome, between men and women, or cross-nationally. We investigate this using contemporaneous national probability survey data from Britain and France. Data were analysed for 17-29 year-olds in Britain's third National Survey of Sexual Attitudes and Lifestyles (Natsal-3, n = 5959) undertaken 2010-2012, and the 2010 French Fertility, Contraception and Sexual Dysfunction survey (FECOND, n = 3027). For each country, we estimated the gender-specific prevalence of sex before-16, contraceptive-use, conception before-20, and abortion in the event of conception, and used logistic regression to examine associations between two measures of socioeconomic status-educational-level and parental socioeconomic-group-and each outcome. We tested for interactions between socioeconomic characteristics and country, and socioeconomic characteristics and gender, for each outcome. For each outcome, Britain and France differed with regard to prevalence but associations with socioeconomic characteristics were similar. Respondents of higher educational level, and, less consistently, with parents from higher socioeconomic-groups, were less likely to report sex before-16 (Britain, men: adjusted OR (aOR) 0.5, women: aOR 0.5; France, men: aOR 0.5, women: aOR 0.5), no contraception at first sex (Britain, men: aOR 0.4, women: aOR 0.6; France, men: aOR 0.4, women: aOR 0.4), pregnancy before-20 (Britain: aOR 0.3; France: aOR 0.1), and in Britain, a birth rather than an abortion in the event of conception (Britain: aOR 3.1). We found no strong evidence of variation in the magnitude of the associations with socioeconomic characteristics by country or gender. Population level differences in conception and abortion rates between the two countries may partly be driven by the larger proportion

  18. Understanding differences in conception and abortion rates among under-20 year olds in Britain and France: Examining the contribution of social disadvantage

    PubMed Central

    Bajos, Nathalie; Slaymaker, Emma; Wellings, Kaye; Mercer, Catherine H.

    2017-01-01

    Objectives Socioeconomic status has been shown to be associated with sexual activity, contraceptive-use, pregnancy and abortion among young people. Less is known about whether the strength of the association differs for each outcome, between men and women, or cross-nationally. We investigate this using contemporaneous national probability survey data from Britain and France. Methods Data were analysed for 17–29 year-olds in Britain’s third National Survey of Sexual Attitudes and Lifestyles (Natsal-3, n = 5959) undertaken 2010–2012, and the 2010 French Fertility, Contraception and Sexual Dysfunction survey (FECOND, n = 3027). For each country, we estimated the gender-specific prevalence of sex before-16, contraceptive-use, conception before-20, and abortion in the event of conception, and used logistic regression to examine associations between two measures of socioeconomic status–educational-level and parental socioeconomic-group–and each outcome. We tested for interactions between socioeconomic characteristics and country, and socioeconomic characteristics and gender, for each outcome. Results For each outcome, Britain and France differed with regard to prevalence but associations with socioeconomic characteristics were similar. Respondents of higher educational level, and, less consistently, with parents from higher socioeconomic-groups, were less likely to report sex before-16 (Britain, men: adjusted OR (aOR) 0.5, women: aOR 0.5; France, men: aOR 0.5, women: aOR 0.5), no contraception at first sex (Britain, men: aOR 0.4, women: aOR 0.6; France, men: aOR 0.4, women: aOR 0.4), pregnancy before-20 (Britain: aOR 0.3; France: aOR 0.1), and in Britain, a birth rather than an abortion in the event of conception (Britain: aOR 3.1). We found no strong evidence of variation in the magnitude of the associations with socioeconomic characteristics by country or gender. Conclusions Population level differences in conception and abortion rates between the two

  19. Modeled dietary impact of industry-wide food and beverage reformulations in the United States and France.

    PubMed

    Gressier, Mathilde; Privet, Lisa; Mathias, Kevin Clark; Vlassopoulos, Antonis; Vieux, Florent; Masset, Gabriel

    2017-07-01

    Background: Food reformulation has been identified as a strategy to improve nutritional intakes; however, little is known about the potential impact of industry-wide reformulations. Objective: The aim of the study was to model the dietary impact of food and beverage reformulation following the Nestlé Nutritional Profiling System (NNPS) standards for children, adolescents, and adults in the United States and France. Design: Dietary intakes of individuals aged ≥4 y were retrieved from nationally representative surveys: the US NHANES 2011-2012 ( n = 7456) and the French Individual and National Survey on Food Consumption ( n = 3330). The composition of all foods and beverages consumed were compared with the NNPS standards for energy, total and saturated fats, sodium, added sugars, protein, fiber, and calcium. Two scenarios were modeled. In the first, the nutrient content of foods and beverages was adjusted to the NNPS standards if they were not met. In the second, products not meeting the standards were replaced by the most nutritionally similar alternative meeting the standards from the same category. Dietary intakes were assessed against local nutrient recommendations, and analyses were stratified by body mass index and socioeconomic status. Results: Scenarios 1 and 2 showed reductions in US adults' mean daily energy (-88 and -225 kcal, respectively), saturated fats (-4.2, -6.9 g), sodium (-406, -324 mg), and added sugars (-29.4, -35.8 g). Similar trends were observed for US youth and in France. The effects on fiber and calcium were limited. In the United States, the social gradient of added sugars intake was attenuated in both scenarios compared with the baseline values. Conclusions: Potential industry-wide reformulation of the food supply could lead to higher compliance with recommendations in both the United States and France, and across all socioeconomic groups. NNPS standards seemed to be especially effective for nutrients consumed in excess. © 2017 American

  20. VEB-1 Extended-Spectrum β-lactamase–producing Acinetobacter baumannii, France1

    PubMed Central

    Coignard, Bruno; Carbonne, Anne; Blanckaert, Karine; Bajolet, Odile; Bernet, Claude; Verdeil, Xavier; Astagneau, Pascal; Desenclos, Jean-Claude; Nordmann, Patrice

    2006-01-01

    VEB-1 extended-spectrum β-lactamase–producing Acinetobacter baumannii was responsible for an outbreak in hospitals in France. A national alert was triggered in September 2003 when 4 hospitals reported clusters of A. baumannii infection with similar susceptibility profiles. Case definitions and laboratory guidelines were disseminated, and prospective surveillance was implemented; strains were sent to a single laboratory for characterization and typing. From April 2003 through June 2004, 53 hospitals reported 290 cases of A. baumannii infection or colonization; 275 isolates were blaVEB-1-positive and clonally related. Cases were first reported in 5 districts of northern France, then in 10 other districts in 4 regions. Within a region, interhospital spread was associated with patient transfer. In northern France, investigation and control measures led to a reduction of reported cases after January 2004. The national alert enabled early control of new clusters, demonstrating the usefulness of early warning about antimicrobial drug resistance. PMID:16965700

  1. Bottom-up substitution assembly of AuF4-n0,-+nPO3 (n = 1-4): a theoretical study of novel oxyfluoride hyperhalogen molecules and anions AuF4-n(PO3)n0,-

    NASA Astrophysics Data System (ADS)

    Yang, Yi-fan; Cui, Zhong-hua; Ding, Yi-hong

    2014-06-01

    Compounds with high electron affinity, i.e. superhalogens, have continued to attract chemists' attention, due to their potential importance in fundamental chemistry and materials science. It has now proven very effective to build up novel superhalogens with multi-positively charged centres, which are usually called 'hyperhalogens'. Herein, using AuF4- and PO3 as the model building blocks, we made the first attempt to design the Au,P-based hyperhalogen anions AuF4-n(PO3)n- (n = 1-4) at the B3LYP/6-311+G(d)&SDD and CCSD(T)/6-311+G(d)&SDD (single-point) levels (6-311+G(d) for O, F, P and SDD for Au). Notably, for all the considered Au,P systems, the ground state bears a dioxo-bonded structure with n ≤ 3, which is significantly more stable than the usually presumed mono-oxo-bonded one. Moreover, the clustering of the -PO3 moieties becomes energetically favoured for n ≥ 3. The ground states of AuP4O120,- are the first reported cage-like oxide hyperhalogens. Thus, the -PO3 moiety cannot be retained during the 'bottom-up' assembly. The vertical detachment energy (VDE) value of the most stable AuF4-n(PO3)n- (n = 1-4) ranges from 7.16 to 8.20 eV, higher than the VDE values of the corresponding building blocks AuF4- (7.08 eV) and PO3- (4.69 eV). The adiabatic detachment energy values of these four hyperhalogens exceed 6.00 eV. Possible generation routes for AuF4-n(PO3)n- (n = 1-4) were discussed. The presently designed oxyfluorides not only enriches the family of hyperhalogens, but also demonstrates the great importance of considering the structural transformation during the superhalogen → hyperhalogen design such as for the present Au-P based systems.

  2. A cross-cultural comparison of population gambling patterns and regulatory frameworks: France and Québec.

    PubMed

    Kairouz, Sylvia; Paradis, Catherine; Nadeau, Louise; Tovar, Marie-Line; Pousset, Maud

    2016-12-01

    Few empirical studies have examined the relationships between differing regulatory approaches and patterns of gambling behaviors. This article reports on a correlational cross-cultural comparison of differences in the regulatory approaches and gambling behavior among general adult populations in France and Québec, Canada. We drew data from two large population surveys conducted in France and Québec (N=27 653 and N=11 888, respectively). We found diverging and converging aspects of government regulatory policies. Statistical analyses demonstrated significantly higher participation rates and prevalence of 'assiduous gamblers' in Québec. In France, among assiduous gamblers, the proportion of moderate-risk and probable pathological gamblers is significantly higher. Future research should examine environmental conditions and varying gambling offerings, as well as gambling regulation, to determine their potential influence on gambling behaviors.

  3. Frequency and correlates of late presentation for HIV infection in France: older adults are a risk group - results from the ANRS-VESPA2 Study, France.

    PubMed

    Wilson, Kayigan d'Almeida; Dray-Spira, Rosemary; Aubrière, Cindy; Hamelin, Christine; Spire, Bruno; Lert, France

    2014-01-01

    Correlates of late presentation (LP) for HIV infection in Metropolitan France and French overseas departments (FODs) were assessed among HIV-infected patients recently diagnosed, using data from a large cross-sectional survey, representative of the French HIV-infected population, conducted in 2011. LP was defined as presentation with either clinical AIDS events within the calendar year of diagnosis or CD4 < 350/mm(3) and presentation with advanced disease (PAD) was defined as presentation with either clinical AIDS events or CD4 < 200/mm(3). Correlates of LP/PAD were assessed through logistic modelling, separately in Metropolitan France and FODs. In Metropolitan France, 47.7% of participants were late presenters and 29.3% presented with advanced disease. LP was more frequent among male and female migrants from sub-Saharan Africa (SSA; 58.5% and 56.4%) and non-African heterosexual males (61.8%) than among men who have sex with men (34.8%). In FODs, 53.2% of participants were late presenters and 36.8% presented with an advanced disease. LP was more frequent among men than women (60.6% vs. 45.3%) and among those with a lower level of education (56.6% vs. 47.5%). A consistent positive association was found in adjusted analyses between LP/PAD and increasing age at diagnosis among all subpopulations, in both settings. In Metropolitan France, among men who have sex with men, those self-declaring as bisexual were at higher risk of LP/PAD; among non-African heterosexual males and females, religiosity was associated with increased risk of LP/PAD; and among SSA migrants, those diagnosed within the year following their arrival in France were at higher risk of LP/PAD. Older age at diagnosis is a major risk factor for LP/PAD independently of any other socio-demographic characteristics. Promotion of HIV testing should be renewed to target each subgroup at risk while paying a particular attention to middle-aged or older adults whose attitudes and beliefs towards HIV/AIDS might

  4. Predictors of Publication Productivity Among Hospital Pharmacists in France and Quebec

    PubMed Central

    Lelièvre, Joachim; Lebel, Denis; Prot-Labarthe, Sonia

    2011-01-01

    Objective To describe publications by hospital pharmacists in France and Quebec and evaluate factors predictive of publication productivity. Method Variables related to scientific publication productivity were identified through a search of the literature and organized into 4 themes (ie, personal and professional characteristics, hospital activities, research and publishing activities, publication-related motivations and perceptions). A questionnaire was developed that included short-answer items and 58 multiple-choice questions to determine respondents' level of agreement with statements about their motivations and perceptions surrounding publishing. Results Four hundred twenty-two hospital pharmacists (218 respondents from France and 204 from Quebec) were recruited. Respondents from France were more prolific than those from Quebec, even when considering factors such as time worked and gender. Furthermore, the percentage of respondents working in a university health center was lower in France than Quebec (46% vs. 70%, p = 0.001), as was the percentage of respondents indicating a mastery of English (43% vs. 88%, p = 0.001). Conclusion Seven factors were predictive of the number of publications per respondent in France and Quebec: practicing hospital pharmacy in France, being male, having academic duties or a PhD, having participated in a clinical trial, having secured funding in one's own name for a research project, and allocating a greater number of hours per week to research. PMID:21451771

  5. Matgéné: a program to develop job-exposure matrices in the general population in France.

    PubMed

    Févotte, Joëlle; Dananché, Brigitte; Delabre, Laurène; Ducamp, Stephane; Garras, Loïc; Houot, Marie; Luce, Danièle; Orlowski, Ewa; Pilorget, Corinne; Lacourt, Aude; Brochard, Patrick; Goldberg, Marcel; Imbernon, Ellen

    2011-10-01

    Matgéné is a program to develop job-exposure matrices (JEMs) adapted to the general population in France for the period since 1950. The aim is to create retrospective exposure assessment tools for estimating the prevalence of occupational exposure to various agents that can then be correlated to health-related parameters. JEMs were drawn up by a team of six industrial hygienists who based their assessments on available occupational measurement, economic and statistical data, and several thousand job descriptions from epidemiological studies performed in France since 1984. Each JEM is specific to one agent, assessing exposure for a set of homogeneous combinations (occupation × activity × period) according to two occupational classifications (ISCO 1968 and PCS 1994) and one economic activities classification (NAF 2000). The cells of the JEM carry an estimate of the probability and level of exposure. Level is estimated by the duration and intensity of exposure-linked tasks or by description of the tasks when exposure measurement data are lacking for the agent in question. The JEMs were applied to a representative sample of the French population in 2007, and prevalence for each exposure was estimated in various population groups. All documents and data are available on a dedicated website. By the end of 2010, 18 JEMs have been developed and eight are under development, concerning a variety of chemical agents: organic and mineral dust, mineral fibers, and solvents. By implementation in the French population, exposure prevalences were calculated at different dates and for complete careers, and attributable risk fractions were estimated for certain pathologies. Some of these results were validated by comparison with those of other programs. Initial Matgéné JEMs results are in agreement with the French and international literature, thus validating the methodology. Exposure estimates precision, however, vary between agents and according to the amount of exposure

  6. [Report on chronic dialysis in France in 2016].

    PubMed

    Société Francophone de Néphrologie Dialyse Et Transplantation

    2017-04-01

    The report on dialysis in France in 2016 from the French Speaking Society of Nephrology Dialysis and Transplantation (SFNDT) provides an exhaustive and documented inventory on dialysis in France. It underlines the organizations that are important in 2016 to maintain a high quality dialysis. Several measures are proposed to maintain and improve the care of dialysis in France: (1) The regulation of dialysis treatment in France must be maintained; (2) a burden of care indicator is proposed to ensure that patients requiring the most care are treated in the centers. Proposals are also made to stimulate peritoneal dialysis offers, (3) to improve the calculation of the cost of dialysis and warn against lower reimbursement rates of dialysis, (4) to reduce transport costs by minimizing transport by ambulance (5). The SFNDT recalls recent recommendations concerning access to the renal transplant waiting list, are recalled; (6) as well as recommendations that require waiting until clinical signs are present to start dialysis (7). The SFNDT makes the proposal to set up advanced renal failure units. These units are expected to develop care that is not supported today: consultation with a nurse, a dietician, a social worker or psychologist, palliative care, and coordination (8). Finally, the financial and human resources for pediatric dialysis should be maintained. Copyright © 2017. Published by Elsevier Masson SAS.

  7. Cannabis use during pregnancy in France in 2010.

    PubMed

    Saurel-Cubizolles, M-J; Prunet, C; Blondel, B

    2014-07-01

    The aim was to estimate the proportion of women who reported cannabis use during pregnancy, to analyse the demographic and social characteristics of users, and the link between cannabis use and either preterm or small-for-gestational-age birth. Data were obtained from interviews of a representative sample of women giving birth in France in 2010 in the days after delivery, and from their medical records. All maternity units in France. The analysis includes women with live singleton births in metropolitan France who responded to the question about cannabis use during pregnancy: in total, 13 545 women. The percentage of cannabis users during pregnancy was estimated, and variations according to social characteristics were described. Logistic regression analyses were used to investigate any associations between cannabis use and preterm birth or small-for-gestational-age status. Percentage of cannabis use, preterm birth rate, and small-for-gestational-age rate. In all, 1.2% of women reported having used cannabis during pregnancy. This percentage was higher among younger women, women living alone, or women who had a low level of education or low income. It was also associated with tobacco use and drinking alcohol. Cannabis users had higher rates of spontaneous preterm births: 6.4 versus 2.8%, for an adjusted odds ratio (aOR) of 2.15 (95% CI 1.10-4.18). The corresponding aOR was 2.64 (95% CI 1.12-6.22) among tobacco smokers and 1.22 (95% CI 0.29-5.06) among non-tobacco smokers. Although the reported rate of cannabis use during pregnancy in France is low, efforts should be continued to inform women and healthcare providers about the potential consequences of its use. © 2014 Royal College of Obstetricians and Gynaecologists.

  8. 40 CFR 721.285 - Acetamide, N-[4-(pentyloxy)phenyl]-, acetamide, N-[2-nitro-4-(pentyloxy)phenyl]-, and acetamide...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... § 721.90 (a)(4), (b)(4), and (c)(4) (where N = 90 ppb for PMNs P-92-31 and P-92-32, and N = 30 ppb for P... reporting. (1) The chemical substances identified as acetamide, N-[4-(pentyloxy)phenyl]- (PMN P-92-31), acetamide, N-[2-nitro-4-(pentyloxy)phenyl]- (PMN P-92-32), and acetamide, N-[2-amino-4-(pentyloxy)phenyl...

  9. 40 CFR 721.285 - Acetamide, N-[4-(pentyloxy)phenyl]-, acetamide, N-[2-nitro-4-(pentyloxy)phenyl]-, and acetamide...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... § 721.90 (a)(4), (b)(4), and (c)(4) (where N = 90 ppb for PMNs P-92-31 and P-92-32, and N = 30 ppb for P... reporting. (1) The chemical substances identified as acetamide, N-[4-(pentyloxy)phenyl]- (PMN P-92-31), acetamide, N-[2-nitro-4-(pentyloxy)phenyl]- (PMN P-92-32), and acetamide, N-[2-amino-4-(pentyloxy)phenyl...

  10. Access to health insurance coverage among sub-Saharan African migrants living in France: Results of the ANRS-PARCOURS study.

    PubMed

    Vignier, Nicolas; Desgrées du Loû, Annabel; Pannetier, Julie; Ravalihasy, Andrainolo; Gosselin, Anne; Lert, France; Lydié, Nathalie; Bouchaud, Olivier; Dray Spira, Rosemary

    2018-01-01

    Migrants' access to care depends on their health insurance coverage in the host country. We aimed to evaluate in France the dynamic and the determinants of health insurance coverage acquisition among sub-Saharan migrants. In the PARCOURS life-event retrospective survey conducted in 2012-2013 in health-care facilities in the Paris region, data on health insurance coverage (HIC) each year since arrival in France has been collected among three groups of sub-Saharan migrants recruited in primary care centres (N = 763), centres for HIV care (N = 923) and for chronic hepatitis B care (N = 778). Year to year, the determinants of the acquisition and lapse of HIC were analysed with mixed-effects logistic regression models. In the year of arrival, 63.4% of women and 55.3% of men obtained HIC. But three years after arrival, still 14% of women and 19% of men had not obtained HIC. HIC acquisition was accelerated in case of HIV or hepatitis B infection, for migrants arrived after 2000, and for women in case of pregnancy and when they were studying. Conversely, it was slowed down in case of lack of a residency permit and lack of financial resources for men. In addition, women and men without residency permits were more likely to have lost HIC when they had one. In France, the health insurance system aiming at protecting all, including undocumented migrants, leads to a prompt access to HIC for migrants from sub-Saharan Africa. Nevertheless, this access may be impaired by administrative and social insecurities.

  11. Access to health insurance coverage among sub-Saharan African migrants living in France: Results of the ANRS-PARCOURS study

    PubMed Central

    Desgrées du Loû, Annabel; Pannetier, Julie; Ravalihasy, Andrainolo; Gosselin, Anne; Lert, France; Lydié, Nathalie; Bouchaud, Olivier; Dray Spira, Rosemary

    2018-01-01

    Background Migrants’ access to care depends on their health insurance coverage in the host country. We aimed to evaluate in France the dynamic and the determinants of health insurance coverage acquisition among sub-Saharan migrants. Methods In the PARCOURS life-event retrospective survey conducted in 2012–2013 in health-care facilities in the Paris region, data on health insurance coverage (HIC) each year since arrival in France has been collected among three groups of sub-Saharan migrants recruited in primary care centres (N = 763), centres for HIV care (N = 923) and for chronic hepatitis B care (N = 778). Year to year, the determinants of the acquisition and lapse of HIC were analysed with mixed-effects logistic regression models. Results In the year of arrival, 63.4% of women and 55.3% of men obtained HIC. But three years after arrival, still 14% of women and 19% of men had not obtained HIC. HIC acquisition was accelerated in case of HIV or hepatitis B infection, for migrants arrived after 2000, and for women in case of pregnancy and when they were studying. Conversely, it was slowed down in case of lack of a residency permit and lack of financial resources for men. In addition, women and men without residency permits were more likely to have lost HIC when they had one. Conclusion In France, the health insurance system aiming at protecting all, including undocumented migrants, leads to a prompt access to HIC for migrants from sub-Saharan Africa. Nevertheless, this access may be impaired by administrative and social insecurities. PMID:29447257

  12. Crystal structure of di-μ-chlorido-bis-(chlorido-{N1,N1-diethyl-N4-[(pyridin-2-yl-κN)methyl-idene]benzene-1,4-di-amine-κN4}mercury(II)).

    PubMed

    Faizi, Md Serajul Haque; Dege, Necmi; Goleva, Kateryna

    2017-06-01

    The title dinuclear mercury(II) complex, [Hg 2 Cl 4 (C 16 H 19 N 3 ) 2 ], synthesized from the pyridine-derived Schiff base ( E )- N 1 , N 1 -diethyl- N 4 -[(pyridin-2-yl)methyl-idene]benzene-1,4-di-amine (DPMBD), has inversion symmetry. The five-coordinated Hg II atoms have distorted square-pyramidal stereochemistry comprising two N-atom donors from bidentate chelate BPMBD ligands and three Cl-atom donors, two bridging and one monodentate. The dihedral angle between the benzene and the pyridine rings in the BPMBD ligand is 7.55 (4)°. In the crystal, the dinuclear mol-ecules are linked by weak C-H⋯Cl hydrogen bonds, forming zigzag ribbons lying parallel to [001]. Also present in the structure are π-π inter-actions between benzene and pyridine rings [minimum ring-centroid separation = 3.698 (8) Å].

  13. Paediatric clinical research from the perspective of hospital pharmacists from France and Canada.

    PubMed

    Guérin, Aurélie; Tanguay, Cynthia; Lebel, Denis; Prot-Labarthe, Sonia; Bourdon, Olivier; Bussières, Jean-François

    2014-12-01

    To compare pharmacy support for paediatric research services in France and Canada and to describe the perception of pharmacists and rank the paediatric clinical research issues. This was a cross-sectional descriptive study. All paediatric hospitals from Canada and the main hospitals from France were contacted. A survey was conducted from May-September 2012. Descriptive statistics were performed. Results from 11 paediatric hospitals in Canada (11/12, 92%) and 11 (11/18, 61%) in France were obtained. There was a similar number of ongoing paediatric clinical trials per hospital in France versus Canada (38 (10-81) versus 20 (4-178)). A lower number of pharmacists per hospital was observed in France (17 (11.5-35) versus 45 (18.9-76.8)), but a similar number of pharmacists were assigned to clinical trials (1.5 (1-3) versus 1.9 (0.2-17.4)). Institutional protocols represented the majority of paediatric clinical trials in France (61% (14-100) versus 25% (0-100)). Similar pharmacy support services were offered, but the majority of French respondents also offered help for institutional protocol development (91 versus 50% P = 0.063). The main issues associated with paediatric clinical research were absence of financial interest from the pharmaceutical industry, prohibitive cost versus profit ratio, small patient cohorts and the non-availability of the appropriate drug formulations. Difficulties related to pharmaceutical compounding were identified as the main hindrance to paediatric clinical research; particular attention should be paid to these details when setting up a paediatric trial. © 2014 Royal Pharmaceutical Society.

  14. Crystal structures of 4-meth-oxy-N-(4-methyl-phenyl)benzene-sulfonamide and N-(4-fluoro-phenyl)-4-meth-oxy-benzene-sulfonamide.

    PubMed

    Rodrigues, Vinola Z; Preema, C P; Naveen, S; Lokanath, N K; Suchetan, P A

    2015-11-01

    Crystal structures of two N-(ar-yl)aryl-sulfonamides, namely, 4-meth-oxy-N-(4-methyl-phen-yl)benzene-sulfonamide, C14H15NO3S, (I), and N-(4-fluoro-phen-yl)-4-meth-oxy-benzene-sulfonamide, C13H12FNO3S, (II), were determined and analyzed. In (I), the benzene-sulfonamide ring is disordered over two orientations, in a 0.516 (7):0.484 (7) ratio, which are inclined to each other at 28.0 (1)°. In (I), the major component of the sulfonyl benzene ring and the aniline ring form a dihedral angle of 63.36 (19)°, while in (II), the planes of the two benzene rings form a dihedral angle of 44.26 (13)°. In the crystal structure of (I), N-H⋯O hydrogen bonds form infinite C(4) chains extended in [010], and inter-molecular C-H⋯πar-yl inter-actions link these chains into layers parallel to the ab plane. The crystal structure of (II) features N-H⋯O hydrogen bonds forming infinite one dimensional C(4) chains along [001]. Further, a pair of C-H⋯O inter-molecular inter-actions consolidate the crystal packing of (II) into a three-dimensional supra-molecular architecture.

  15. Second-Nearest-Neighbor Effects upon N NMR Shieldings in Models for Solid Si 3N 4and C 3N 4

    NASA Astrophysics Data System (ADS)

    Tossell, J. A.

    1997-07-01

    NMR shifts are generally determined mainly by the nearest-neighbor environment of an atom, with fairly small changes in the shift arising from differences in the second-nearest-neighbor environment. Previous calculations on the (SiH3)3N molecule used as a model for the local environment of N in crystalline α- and β-Si3N4gave N NMR shieldings much larger than those measured in the solids and gave the wrong order for the shifts of the inequivalent N sites (e.g., N1 and N2 in β-Si3N4). We have now calculated the N NMR shieldings in larger molecular models for the N2 site of β-Si3N4and have found that the N2 shielding is greatly reduced when additional N1 atoms (second-nearest-neighbors to the central N2) are included. The calculated N2 shieldings (using the GIAO method with the 6-31G* basis set and 6-31G* SCF optimized geometries) are 288.1, 244.7, and 206.0 ppm for the molecules (SiH3)3N, Si6N5H15, and Si9N9H21(central N2), respectively, while the experimental shielding of N2 in β-Si3N4is about 155 ppm. Second-nearest-neighbor effects of only slightly smaller magnitude are calculated for the analog C molecules. At the same time, the effects of molecule size upon Si NMR shieldings and N electric field gradients are small. The local geometries at the N2-like Ns in C6N5H15and C9N9H21are calculated to be planar, consistent with the planar local geometry recently calculated for N in crystalline C3N4using density functional theory.

  16. [Rabies in France: an update].

    PubMed

    Jaussaud, R; Strady, C; Liénard, M; Strady, A

    2000-08-01

    In 1996, rabies was responsible for more than 35,000 deaths worldwide. Three cases of human rabies that had been contracted abroad were diagnosed in France during the same year. Cases notified in 1997 followed exposure outside the country. Fox, bat, and dog rabies are reviewed on the basis of the latest epidemiological data obtained in France. Two cases of fox rabies diagnosed in 1998 occurred at the border between France and Germany, thus preventing five French departments bordering Germany from being officially declared rabies-free in 1999. The campaigns for oral immunization of foxes that are led since 1986 are responsible for the decrease in rabies incidence. Though not well known, bat rabies is a reality in France, involving either European virus strains (five cases all over the country) or African virus strains that are carried along by imported tropical bats. Dogs rabies is also today an imported disease. The decrease in risk for rabies has resulted from the conjunction of multiple efforts: extensive programs aimed at oral vaccination of foxes in France and its neighboring countries, efficient epidemiological survey, sanitary controls at borders, ban on importing tropical bats. Furthermore, recommendations for preventive pre-exposure immunization have recently been changed, leading to modifications of the French licensing form.

  17. Pupil's Beliefs about the Transformations of Energy in Three Countries (Canada, France and Morocco)

    ERIC Educational Resources Information Center

    Métioui, Abdeljalil; MacWillie, Mireille Baulu

    2015-01-01

    A qualitative research approach was chosen to analyse the conceptions of pupils attending elementary school from Canada (N = 135), France (N = 30) and Morocco (N = 92) between 10 and 12 years of age. Their conceptions were identified while being mobilised on energy transformations during the working of a simple electric circuit made of a battery,…

  18. Scalar Casimir energies in M4>=N for even N

    NASA Astrophysics Data System (ADS)

    Kantowski, R.; Milton, Kimball A.

    1987-01-01

    We construct a Green's-function formalism for computing vacuum-fluctuation energies of scalar fields in 4+N dimensions, where the extra N dimensions are compactified into a hypersphere SN of radius a. In all cases a leading cosmological energy term ucosmo~aN/b4+N results. Here b is an ultraviolet cutoff at the Planck scale. In all cases an unambiguous Casimir energy is computed. For odd N these energies agree with those calculated by Candelas and Weinberg. For even N, the Casimir energy is logarithmically divergent: uCasimir~(αN/a4)ln(a/b). The coefficients αN are computed in terms of Bernoulli numbers.

  19. Pharmacy discounts on generic medicines in France: is there room for further efficiency savings?

    PubMed

    Kanavos, Panos; Taylor, David

    2007-10-01

    In France control of pharmaceutical expenditure has been a policy priority for many years and generic policies have featured prominently on the policy agenda. Measures including reference pricing, generic substitution and international non-proprietary name (INN) prescribing have been introduced in recent years. Generic manufacturers and wholesalers may offer discounts, rebates or promotions to pharmacies in order to gain an edge over their competitors, but their true extent is unknown. To identify the amplitude of discounts on generic medicines, and whether wholesalers or generic manufacturers offer these beyond officially negotiated margins and allowable discounts, by conducting a pilot study. Data on net prices were acquired for all available presentations of 11 generic molecules selected across different therapeutic categories included in the 40 most selling generic products in 2005. Data were obtained via a questionnaire survey followed by interview with selected pharmacies (n = 4) and whole-salers (n = 2). Pharmacies and wholesalers participated in this study subject to confidentiality and anonymity. Pharmacies usually prefer to buy generic products directly from manufacturers rather than from wholesalers in order to avoid paying additional margins imposed by wholesalers. Discounts are mostly price-related and generally vary from 20 to 70% off the wholesaler selling price (WSP), on top of the officially allowed 10.74%. Discounts on the ex-factory price (EFP) are much lower, typically around 7.5%. Discounts are prohibited for branded products, beyond the officially allowed ceiling of 2.5%. While horizontal integration among pharmacies is disallowed, pharmacies may form purchasing groups allowing them to realise greater discounts from suppliers. Overall, the evidence suggests that discounts occur in France beyond what may be allowable and their extent can be significant. If general discount levels for generic medicines are as high as this pilot study suggests

  20. Bioelectromagnetics Research in France--An Assessment.

    DTIC Science & Technology

    1984-06-29

    to level of the Defense Department. He was 5 years. The latter will help demon- replaced in normal rotation by a manager strate the breadth and scope...engineering. Unless support is found Ondes Electromagnetiques et Biologie immediately in industry or in other (Jouy en Josas, France, 1980), countries, France...Bioelectromagnetics de URSI, Ondes Electromagnetiques et Journal, not one French paper has been Biologie (Jouy en Josas, France, published in it. Whether any were

  1. 76 FR 28637 - Airworthiness Directives; Eurocopter France Model AS350B, B1, B2, B3, BA, and EC130 B4 Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-18

    ... Airworthiness Directives; Eurocopter France Model AS350B, B1, B2, B3, BA, and EC130 B4 Helicopters AGENCY... Register as of June 22, 2011. ADDRESSES: You may examine the AD docket on the Internet at http... available data, we have determined that air safety and the public interest require adopting the AD as...

  2. Chateaubriant, France

    NASA Image and Video Library

    2010-03-08

    This image, acquired 11-05-2007 by NASA Terra spacecraft, shows the city of Chateaubriant, France, surrounded by very old farmsteads. The surrounding countryside presents an interesting pattern of randomly oriented, small individual farmsteads.

  3. Early signal of diverted use of tropicamide eye drops in France.

    PubMed

    Ponté, Camille; Pi, Christian; Palmaro, Aurore; Jouanjus, Emilie; Lapeyre-Mestre, Maryse

    2017-08-01

    Tropicamide is a mydriatic drug used as eye-drops for diagnostic or therapeutic purposes. From 2013, a diverted use by intravenous route has been suspected in Eastern Europe in opioids users. To date, no signal of misuse has been identified in France. The aims of this study were to investigate any early signals of a diverted use of tropicamide eye drops and to collect information regarding motives for the misuse and tropicamide-induced effects. Information was obtained at three levels: (1) at regional level (Midi-Pyrénées area), from reimbursement data and pharmacists' reports on suspicious requests; (2) at national level: from reimbursement data and prescriptions suggesting possible abuse from the OSIAP (Ordonnances Suspectes, Indicateur d'Abus Possible) survey; and (3) at international level: from VigiBase ® reports and Web sources. Beta-blocker eye-drops were used as comparators. In France, in 2014-2015, 17 (0.91%, 95% CI [0.53-1.46%]) falsified prescriptions involving tropicamide were identified in the OSIAP survey (compared with 0%, 95% CI [0-0.19%] for beta-blockers). Moreover, 37 other suspicious prescriptions were presented in 2015 (notified in 2016). In Midi-Pyrénées, seven patients aged 35-49 were reimbursed for 19-45 vials of 10 ml, in a year. Since September 2014, the regional Addictovigilance Centre has received 91 notifications of suspicious requests to obtain tropicamide. In VigiBase ® , two cases were identified but none in France. An increased interest in tropicamide-related Internet searches was observed from Russia and Ukraine. These results represent the first early warnings of a tropicamide diverted use in France. Tropicamide abusers would seek euphoria or hallucinations. The high doses involved in intravenous administration could lead to serious complications. © 2017 The British Pharmacological Society.

  4. Clustering of quasars in a wide luminosity range at redshift 4 with Subaru Hyper Suprime-Cam Wide-field imaging

    NASA Astrophysics Data System (ADS)

    He, Wanqiu; Akiyama, Masayuki; Bosch, James; Enoki, Motohiro; Harikane, Yuichi; Ikeda, Hiroyuki; Kashikawa, Nobunari; Kawaguchi, Toshihiro; Komiyama, Yutaka; Lee, Chien-Hsiu; Matsuoka, Yoshiki; Miyazaki, Satoshi; Nagao, Tohru; Nagashima, Masahiro; Niida, Mana; Nishizawa, Atsushi J.; Oguri, Masamune; Onoue, Masafusa; Oogi, Taira; Ouchi, Masami; Schulze, Andreas; Shirasaki, Yuji; Silverman, John D.; Tanaka, Manobu M.; Tanaka, Masayuki; Toba, Yoshiki; Uchiyama, Hisakazu; Yamashita, Takuji

    2018-01-01

    We examine the clustering of quasars over a wide luminosity range, by utilizing 901 quasars at \\overline{z}_phot˜ 3.8 with -24.73 < M1450 < -22.23 photometrically selected from the Hyper Suprime-Cam Subaru Strategic Program (HSC-SSP) S16A Wide2 date release and 342 more luminous quasars at 3.4 < zspec < 4.6 with -28.0 < M1450 < -23.95 from the Sloan Digital Sky Survey that fall in the HSC survey fields. We measure the bias factors of two quasar samples by evaluating the cross-correlation functions (CCFs) between the quasar samples and 25790 bright z ˜ 4 Lyman break galaxies in M1450 < -21.25 photometrically selected from the HSC dataset. Over an angular scale of 10.0" to 1000.0", the bias factors are 5.93+1.34-1.43 and 2.73+2.44-2.55 for the low- and high-luminosity quasars, respectively, indicating no significant luminosity dependence of quasar clustering at z ˜ 4. It is noted that the bias factor of the luminous quasars estimated by the CCF is smaller than that estimated by the auto-correlation function over a similar redshift range, especially on scales below 40.0". Moreover, the bias factor of the less-luminous quasars implies the minimal mass of their host dark matter halos is 0.3-2 × 1012 h-1 M⊙, corresponding to a quasar duty cycle of 0.001-0.06.

  5. Comparative effectiveness and acceptability of home-based and clinic-based sampling methods for sexually transmissible infections screening in females aged 14-50 years: a systematic review and meta-analysis.

    PubMed

    Odesanmi, Tolulope Y; Wasti, Sharada P; Odesanmi, Omolola S; Adegbola, Omololu; Oguntuase, Olubukola O; Mahmood, Sajid

    2013-12-01

    Home-based sampling is a strategy to enhance uptake of sexually transmissible infection (STI) screening. This review aimed to compare the screening uptake levels of home-based self-sampling and clinic-based specimen collection for STIs (chlamydia (Chlamydia trachomatis), gonorrhoea (Neisseria gonorrhoeae) and trichomoniasis) in females aged 14-50 years. Acceptability and effect on specimen quality were determined. Sixteen electronic databases were searched from inception to September 2012. Randomised controlled trials (RCTs) comparing the uptake levels of home-based self-sampling and clinic-based sampling for chlamydia, gonorrhoea and trichomoniasis in females aged 14-50 years were eligible for inclusion. The risk of bias in the trials was assessed. Risk ratios (RRs) for dichotomous outcomes were meta-analysed. Of 3065 papers, six studies with seven RCTs contributed to the final review. Compared with clinic-based methods, home-based screening increased uptake significantly (P=0.001-0.05) in five trials and was substantiated in a meta-analysis (RR: 1.55; 95% confidence interval: 1.30-1.85; P=0.00001) of two trials. In three trials, a significant preference for home-based testing (P=0.001-0.05) was expressed. No significant difference was observed in specimen quality. Sampling was rated as easy by a significantly higher number of women (P=0.01) in the clinic group in one trial. The review provides evidence that home-based testing results in greater uptake of STI screening in females (14-50 years) than clinic-based testing without compromising quality in the developed world. Home collection strategies should be added to clinic-based screening programs to enhance uptake.

  6. Synthesis and structure of the extended phosphazane ligand [(1,4-C6H4){N(μ-PN(t)Bu)2N(t)Bu}2](4).

    PubMed

    Sevilla, Raquel; Less, Robert J; García-Rodríguez, Raúl; Bond, Andrew D; Wright, Dominic S

    2016-02-07

    The reaction of the phenylene-bridged precursor (1,4-C6H4)[N(PCl2)2]2 with (t)BuNH2 in the presence of Et3N gives the new ligand precursor (1,4-C6H4)[N(μ-N(t)Bu)2(PNH(t)Bu)2]2, deprotonation of which with Bu2Mg gives the novel tetraanion [(1,4-C6H4){N(μ-N(t)Bu)2(PN(t)Bu)2}2](4-).

  7. Incidence of acute intussusception among infants in eastern France: results of the EPIstudy trial.

    PubMed

    Fotso Kamdem, Arnaud; Vidal, Chrystelle; Pazart, Lionel; Leroux, Franck; Pugin, Aurore; Savet, Caroline; Sainte-Claire Deville, Geoffroy; Riou França, Lionel; Guillemot, Didier; Massol, Jacques

    2017-03-01

    The incidence of intussusception in infants varies around the world. The epidemiology of intussusception in France has never been prospectively studied. We performed a prospective observational study with systematic inclusion of all infants aged <1 year with suspected intussusception admitted to the emergency departments of the hospitals in the eastern region of France (98,000 live births per year), from 4/1/2008 to 3/31/2012. Cases were classified using the Brighton Collaboration classification. In total, 185 infants with suspected intussusception were included of which 169 were idiopathic intussusception. Among these 169 cases, 115 (68%) were classed as Brighton level 1 (confirmed cases). Overall incidence of intussusception over the 4 years of the study was 29.8 (95% CI 24.6-35.7) cases per 100,000 live births for level 1 and 37.5 (95% CI 31.7-44.2) cases per 100,000 live births for all cases (levels 1-4). Annual incidence rates of level 1 intussusception were as follows: 44 (95% CI 31.9-59.3), 30.9 (20.9-44.2), 21.7 (13.4-33.2) and 22.1 (13.7-33.8) per 100,000 live births in the 1st, 2nd, 3rd and 4th study years, respectively. The incidence rate of intussusception in the eastern part of France is comparable to that of other European countries. There was a significant trend towards a decrease in the incidence of intussusception. What is known • Intussusception is the most frequent causes of intestinal obstruction in infants and young children. Overall incidence of intussusception in infants aged <1 year varies widely around the world. No specific epidemiological studies have not been conducted in France on intussusception. What is new: • This prospective and multicenter study provides important information about the epidemiology of intussusception in infants in France over a period of 4 years.

  8. Crystal structure of (4-cyano­pyridine-κN){5,10,15,20-tetrakis[4-(benzoyloxy)phenyl]porphyrinato-κ4 N}zinc–4-cyano­pyridine (1/1)

    PubMed Central

    Nasri, Soumaya; Amiri, Nesrine; Turowska-Tyrk, Ilona; Daran, Jean-Claude; Nasri, Habib

    2016-01-01

    In the title compound, [Zn(C72H44N4O8)(C6H4N2)]·C6H4N2 or [Zn(TPBP)(4-CNpy]·(4-CNpy) [where TPBP and 4-CNpy are 5,10,15,20-(tetra­phenyl­benzoate)porphyrinate and 4-cyano­pyridine, respectively], the ZnII cation is chelated by four pyrrole-N atoms of the porphyrinate anion and coordinated by a pyridyl-N atom of the 4-CNpy axial ligand in a distorted square-pyramidal geometry. The average Zn—N(pyrrole) bond length is 2.060 (6) Å and the Zn—N(4-CNpy) bond length is 2.159 (2) Å. The zinc cation is displaced by 0.319 (1) Å from the N4C20 mean plane of the porphyrinate anion toward the 4-cyano­pyridine axial ligand. This porphyrinate macrocycle exhibits major saddle and moderate ruffling and doming deformations. In the crystal, the [Zn(TPBP)(4-CNpy)] complex mol­ecules are linked together via weak C—H⋯N, C—H⋯O and C—H⋯π inter­actions, forming supra­molecular channels parallel to the c axis. The non-coordinating 4-cyano­pyridine mol­ecules are located in the channels and linked with the complex mol­ecules, via weak C—H⋯N inter­actions and π-π stacking or via weak C—H⋯O and C—H⋯π inter­actions. The non-coordinating 4-cyano­pyridine mol­ecule is disordered over two positions with an occupancy ratio of 0.666 (4):0.334 (4). PMID:26958379

  9. Syntheses and structures of [UO2( L)5](ClO4)2 and [U( L')4(H2O)4](ClO4)4 ( L is dimethylformamide, L' is N,N-dimethylcarbamide)

    NASA Astrophysics Data System (ADS)

    Serezhkin, V. N.; Vologzhanina, A. V.; Pushkin, D. V.; Astashkina, D. A.; Savchenkov, A. V.; Serezhkina, L. B.

    2017-09-01

    The reaction of aqueous solutions of uranyl perchlorate with selected organic amides was studied in the dark and under the sunlight. The complexes [UVIO2(C3H7NO)5](ClO4)2 ( I) and [UIV(C3H8N2O)4(H2O)4](ClO4)4 ( II), where C3H7NO is N,N-dimethylformamide ( Dmfa) and C3H8N2O is N,N-dimethylcarbamide ( a-Dmur), were studied by X-ray diffraction. Complex II and the complex UIV( s-Dmur)4(H2O)4(ClO4)4 ( III), where s-Dmur is N,N'-dimethylcarbamide, were studied by IR spectroscopy. Crystals I and II are composed of mononuclear [UO2( Dmfa)5]2+ and [U( Dmur)4(H2O)4]4+ groups as uranium-containing structural units belonging to the crystal-chemical groups AM 7 1 ( A = UVI, M 1 = O2- and Dmfa) and AM 8 1 ( A = UIV, M 1 = Dmur and H2O) of uranium complexes, respectively. The mononuclear uranium- containing complexes in the crystals of U(IV) and U(VI) perchlorates were found to obey the 14 neighbors rule.

  10. 4-Bromo-N-(di-n-propyl-carbamothioyl)-benzamide.

    PubMed

    Binzet, Gün; Flörke, Ulrich; Külcü, Nevzat; Arslan, Hakan

    2009-02-04

    The synthesis of the title compound, C(14)H(19)BrN(2)OS, involves the reaction of 4-bromo-benzoyl chloride with potassium thio-cyanate in acetone followed by condensation of the resulting 4-bromo-benzoyl isothio-cyanate with di-n-propyl-amine. Typical thio-urea carbonyl and thio-carbonyl double bonds, as well as shortened C-N bonds, are observed in the title compound. The short C-N bond lengths in the centre of the mol-ecule reveal the effects of resonance in this part of the mol-ecule. The asymmetric unit of the title compound contains two crystallographically independent mol-ecules, A and B. There is very little difference between the bond lengths and angles of these mol-ecules. In mol-ecule B, one di-n-propyl group is twisted in a -anti-periplanar conformation with C-C-C-H = -179.1 (3)° and the other adopts a -synclinal conformation with C-C-C-H = -56.7 (4)°; in mol-ecule A the two di-n-propyl groups are twisted in + and -anti-periplanar conformations, with C-C-C-H = -179.9 (3) and 178.2 (3)°, respectively. In the crystal, the mol-ecules are linked into dimeric pairs via pairs of N-H⋯S hydrogen bonds.

  11. France acts on electronic cigarettes.

    PubMed

    Cahn, Zachary

    2013-11-01

    France is deciding how to regulate electronic cigarettes. I first consider the French approach and how it contrasts with other attempts at electronic cigarette regulation globally. Next, I critique the individual elements of the French proposal. The overall approach taken by France is a positive development, but banning indoor use appears unnecessary and banning advertising may be counterproductive.

  12. 78 FR 25365 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-01

    ... Airworthiness Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for Eurocopter France... applies. FAA's Determination These helicopters have been approved by the aviation authority of France and...

  13. Predominance of G9P[8] rotavirus strains throughout France, 2014-2017.

    PubMed

    Kaplon, J; Grangier, N; Pillet, S; Minoui-Tran, A; Vabret, A; Wilhelm, N; Prieur, N; Lazrek, M; Alain, S; Mekki, Y; Foulongne, V; Guinard, J; Avettand-Fenoel, V; Schnuriger, A; Beby-Defaux, A; Lagathu, G; Pothier, P; de Rougemont, A

    2018-06-01

    Group A rotavirus is a major cause of acute gastroenteritis in young children worldwide. A prospective surveillance network has been set up in France to investigate rotavirus infections and to detect the emergence of potentially epidemic strains. From 2014 to 2017, rotavirus-positive stool samples were collected from 2394 children under 5 years old attending the paediatric emergency units of 13 large hospitals. Rotaviruses were genotyped by RT-PCR with regard to their outer capsid proteins VP4 and VP7. Genotyping of 2421 rotaviruses showed that after a marked increase in G9P[8] (32.1%) during the 2014-2015 season, G9P[8] became the predominant genotype during the 2015-2016 and 2016-2017 seasons with detection rates of 64.1% and 77.3%, respectively, whereas G1P[8] were detected at low rates of 16.8% and 6.6%, respectively. Phylogenetic analysis of the partial rotavirus VP7 and VP4 coding genes revealed that all of these G9P [8] strains belonged to the lineage III and the P [8]-3 lineage, respectively, and shared the same genetic background (G9-P[8]-I1-R1-C1-M1-A1-N1-T1-E1-H1) as did most of previously detected G9P[8] strains and particularly the emerging G9P[8] strains from the 2004-2005 season in France. G9P[8] rotaviruses have become the predominant circulating genotype for the first time since their emergence a decade ago. In the absence of rotavirus immunization programmes in France, our data give an insight into the natural fluctuation of rotavirus genotypes in a non-vaccinated population and provide a base line for a better interpretation of data in European countries with routine rotavirus vaccination. Copyright © 2017 European Society of Clinical Microbiology and Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

  14. Particle size reduction of Si3N4 with Si3N4 milling hardware

    NASA Technical Reports Server (NTRS)

    Herbell, T. P.; Freedman, M. R.; Kiser, J. D.

    1986-01-01

    The grinding of Si3N4 powder using reaction bonded Si3N4 attrition, vibratory, and ball mills with Si3N4 media was examined. The rate of particle size reduction and the change in the chemical composition of the powder were determined in order to compare the grinding efficiency and the increase in impurity content resulting from mill and media wear for each technique. Attrition and vibratory milling exhibited rates of specific surface area increase that were approximately eight times that observed in ball milling. Vibratory milling introduced the greatest impurity pickup.

  15. 77 FR 54796 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-06

    ... Airworthiness Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA), DOT... France Model AS350 helicopters. This AD requires installing protection sleeves over certain forward... helicopters have been approved by the aviation authority of France and are approved for operation in the...

  16. 78 FR 18230 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-26

    ... Airworthiness Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for Eurocopter France... approved by the aviation authority of France and is approved for operation in the United States. Pursuant...

  17. 78 FR 65871 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-04

    ... Airworthiness Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for Eurocopter France... aviation authority of France and are approved for operation in the United States. Pursuant to our bilateral...

  18. 77 FR 44118 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-27

    ... Airworthiness Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA... airworthiness directive (AD) for Eurocopter France (Eurocopter) Model EC155B1 helicopters with a certain... Determination These helicopters have been approved by the aviation authority of France and are approved for...

  19. 78 FR 25380 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-01

    ... Airworthiness Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for Eurocopter France... Determination These helicopters have been approved by the aviation authority of France and are approved for...

  20. 77 FR 70360 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-26

    ... Airworthiness Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for all Eurocopter France... France and are approved for operation in the United States. Pursuant to our bilateral agreement with...

  1. 78 FR 59306 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-26

    ...-0826; Directorate Identifier 2011-SW-046-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France (Eurocopter) Model... helicopters have been approved by the aviation authority of France and [[Page 59307

  2. 77 FR 57996 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-19

    ... Airworthiness Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for Eurocopter France... directive (AD): 2012-18-08 EUROCOPTER FRANCE: Amendment 39-17184; Docket No. FAA- 2011-1408; Directorate...

  3. 78 FR 857 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-07

    ... Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for Eurocopter France (Eurocopter... been approved by the aviation authority of France and are approved for operation in the United States...

  4. 78 FR 9634 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-11

    ...-0119; Directorate Identifier 2011-SW-034-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France (Eurocopter) Model... helicopter. FAA's Determination These helicopters have been approved by the aviation authority of France and...

  5. 78 FR 21233 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-10

    ... Airworthiness Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for Eurocopter France... (NPRM), which proposed to amend 14 CFR part 39 to include an AD that would apply to Eurocopter France...

  6. 78 FR 59298 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-26

    ...-1158; Directorate Identifier 2010-SW-018-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to revise airworthiness directive (AD) 2011-22-05 for Eurocopter France (Eurocopter...'s Determination These helicopters have been approved by the aviation authority of France and are...

  7. 77 FR 5991 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-07

    ... Airworthiness Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA... airworthiness directive (AD) for the Eurocopter France (ECF) Model AS332L2 helicopter and superseding an AD for... of France and are approved for operation in the United States. Pursuant to our bilateral agreement...

  8. Recent Demographic Developments in France: Relatively Low Mortality at Advanced Ages.

    PubMed

    Prioux, France; Barbieri, Magali

    2012-10-01

    France had 65.3 million inhabitants as of 1 January 2012, including 1.9 million in the overseas départements . The population is slightly younger than that of the European Union as a whole. Population growth continues at the same rate, mainly through natural increase. There are now more African than European immigrants living in France. Fertility was practically stable in 2011 (2.01 children per woman), but the lifetime fertility of the 1971-1972 cohorts reached a historic low in metropolitan France (1.99 children per woman), nevertheless remaining among the highest in Europe. Abortion levels remained stable and rates among young people are no longer increasing. The marriage rate is falling and the divorce rate has stabilized (46.2 divorces per 100 marriages in 2011). The risk of divorce decreases with age, but has greatly increased among the under-70s over the last decade. Life expectancy at birth (78.4 years for men, 85.0 for women) has continued to increase at the same rate, mainly thanks to progress at advanced ages. Among European countries, France has the lowest mortality in the over-65 age group, but it ranks less well for premature mortality.

  9. 77 FR 18967 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-29

    ...-0339; Directorate Identifier 2011-SW-051-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for all Eurocopter France (Eurocopter... Airworthiness Directive (AD): Eurocopter France: Docket No. FAA-2012-0339; Directorate Identifier 2011-SW-051-AD...

  10. 78 FR 44043 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-23

    ...-0635; Directorate Identifier 2012-SW-081-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France (Eurocopter) Model... France and are approved for operation in the United States. Pursuant to our bilateral agreement with...

  11. 78 FR 23462 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-19

    ... Airworthiness Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA... airworthiness directive (AD) for Eurocopter France (Eurocopter) Model AS332C, AS332L, and AS332L1 helicopters... helicopters have been approved by the aviation authority of France and are approved for operation in the...

  12. 78 FR 16200 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-14

    ...-0240; Directorate Identifier 2011-SW-060-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for certain Eurocopter France (Eurocopter... helicopters have been approved by the aviation authority of France and are approved for operation in the...

  13. 77 FR 44509 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-30

    ...-0795; Directorate Identifier 2008-SW-53-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France (Eurocopter) Model... by the aviation authority of the France and are approved for operation in the United States. Pursuant...

  14. 78 FR 33764 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-05

    ...-0479; Directorate Identifier 2011-SW-070-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France (Eurocopter) Model... authority of France and are approved for operation in the United States. Pursuant to our bilateral agreement...

  15. 77 FR 36216 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-18

    ...-0631; Directorate Identifier 2011-SW-021-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France... rulemaking (NPRM). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France... approved by the aviation authority of France and are approved for operation in the United States. Pursuant...

  16. 77 FR 43734 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-26

    ...-0774; Directorate Identifier 2010-SW-057-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France (Eurocopter) Model... Determination This helicopter model is manufactured in France and is type certificated for operation in the...

  17. 78 FR 37154 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-20

    ...-0523; Directorate Identifier 2012-SW-091-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France (Eurocopter) Model... Determination These helicopters have been approved by the aviation authority of France and are approved for...

  18. 78 FR 51115 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-20

    ...-0737; Directorate Identifier 2012-SW-111-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for certain Eurocopter France (Eurocopter... approved by the aviation authority of France and are approved for operation in the United States. Pursuant...

  19. 77 FR 56755 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-14

    ... Airworthiness Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for Eurocopter France... proposed to amend 14 CFR part 39 to include an AD that would apply to Eurocopter France Model SA341G...

  20. A Convenient, TiCl4/SnCl4-Mediated Synthesis of N-Phenyl or N-Aryl Benzamidines and N-Phenylpicolinamidines

    PubMed Central

    Patil, Umesh D.; Mahulikar, Pramod P.

    2012-01-01

    A new, TiCl4-or SnCl4-mediated, solvent-free method was developed for the synthesis of N-Aryl benzamidines and N-phenylpicolinamidines, in moderate-to-good yield, using suitable amines and nitriles as starting materials. PMID:24052858

  1. 77 FR 20319 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-04

    ...-0354; Directorate Identifier 2010-SW-104-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for all Eurocopter France (EC) Model SA... France: Docket No. FAA-2012-0354; Directorate Identifier 2010-SW-104-AD. (a) Applicability This AD...

  2. 77 FR 43738 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-26

    ...-0772; Directorate Identifier 2007-SW-053-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France (Eurocopter) Model... manufactured in France and is type certificated for operation in the United States under the provisions of 14...

  3. 77 FR 50582 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-22

    ... Airworthiness Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for Eurocopter France... 39 to include an AD that would apply to Eurocopter France Model EC155B and EC155B1 helicopters with a...

  4. 77 FR 18965 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-29

    ...-0338; Directorate Identifier 2009-SW-51-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France Model SA341G.... Discussion The Direction Generale de l'Aviation Civile (DGAC), which is the aviation authority for France...

  5. 77 FR 14310 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-09

    ...-0222; Directorate Identifier 2011-SW-007-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for certain Eurocopter France Model AS350... Determination These products have been approved by the aviation authority of France and are approved for...

  6. 77 FR 11787 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-28

    ...-0177; Directorate Identifier 2009-SW-59-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France Model EC155B and... approved by the aviation authority of France and are approved for operation in the United States. Pursuant...

  7. 78 FR 75579 - Low Enriched Uranium From France

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-12

    ... From France Determination On the basis of the record \\1\\ developed in the subject five-year review, the... uranium from France would be likely to lead to continuation or recurrence of material injury to an... Commission are contained in USITC Publication 4436 (December 2013), entitled Low Enriched Uranium from France...

  8. Combined Genotypic, Phylogenetic, and Epidemiologic Analyses of Mycobacterium tuberculosis Genetic Diversity in the Rhône Alpes Region, France.

    PubMed

    Pichat, Catherine; Couvin, David; Carret, Gérard; Frédénucci, Isabelle; Jacomo, Véronique; Carricajo, Anne; Boisset, Sandrine; Dumitrescu, Oana; Flandrois, Jean-Pierre; Lina, Gérard; Rastogi, Nalin

    2016-01-01

    The present work relates to identification and a deep molecular characterization of circulating Mycobacterium tuberculosis complex (MTBC) strains in the Rhône-Alpes region, France from 2000 to 2010. It aimed to provide with a first snapshot of MTBC genetic diversity in conjunction with bacterial drug resistance, type of disease and available demographic and epidemiologic characteristics over an eleven-year period, in the south-east of France. Mycobacterium tuberculosis complex (MTBC) strains isolated in the Rhône-Alpes region, France (n = 2257, 1 isolate per patient) between 2000 and 2010 were analyzed by spoligotyping. MIRU-VNTR typing was applied on n = 1698 strains (with full results available for 974 strains). The data obtained were compared with the SITVIT2 database, followed by detailed genotyping, phylogenetic, and epidemiologic analyses in correlation with anonymized data on available demographic, and epidemiologic characteristics, and location of disease (pulmonary or extrapulmonary TB). The most predominant spoligotyping clusters were SIT53/T1 (n = 346, 15.3%) > SIT50/H3 (n = 166, 7.35%) > SIT42/LAM9 (n = 125, 5.5%) > SIT1/Beijing (n = 72, 3.2%) > SIT47/H1 (n = 71, 3.1%). Evolutionary-recent strains belonging to the Principal Genetic Group (PGG) 2/3, or Euro-American lineages (T, LAM, Haarlem, X, S) were predominant and represented 1768 or 78.33% of all isolates. For strains having drug resistance information (n = 1119), any drug resistance accounted for 14.83% cases vs. 1.52% for multidrug resistance (MDR); and was significantly more associated with age group 21-40 years (p-value<0.001). Extra-pulmonary TB was more common among female patients while pulmonary TB predominated among men (p-value<0.001; OR = 2.16 95%CI [1.69; 2.77]). Also, BOV and CAS lineages were significantly well represented in patients affected by extra-pulmonary TB (p-value<0.001). The origin was known for 927/2257 patients: 376 (40.6%) being French-born vs. 551 (59.4%) Foreign

  9. Socioeconomic Segregation in Large Cities in France and the United States.

    PubMed

    Quillian, Lincoln; Lagrange, Hugues

    2016-08-01

    Past cross-national comparisons of socioeconomic segregation have been undercut by lack of comparability in measures, data, and concepts. Using IRIS data from the French Census of 2008 and the French Ministry of Finance as well as tract data from the American Community Survey (2006-2010) and the U.S. Department of Housing and Urban Development Picture of Subsidized Households, and constructing measures to be as similar as possible, we compare socioeconomic segregation in metropolitan areas with a population of more than 1 million in France and the United States. We find much higher socioeconomic segregation in large metropolitan areas in the United States than in France. We also find (1) a strong pattern of low-income neighborhoods in central cities and high-income neighborhoods in suburbs in the United States, but varying patterns across metropolitan areas in France; (2) that high-income persons are the most segregated group in both countries; (3) that the shares of neighborhood income differences that can be explained by neighborhood racial/ethnic composition are similar in France and the United States; and (4) that government-assisted housing is disproportionately located in the poorest neighborhoods in the United States but is spread across many neighborhood income levels in France. We conclude that differences in government provision of housing assistance and levels of income inequality are likely important contributing factors to the Franco-U.S. difference in socioeconomic segregation.

  10. 78 FR 63429 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-24

    ...-0872; Directorate Identifier 2013-SW-012-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France Model AS332C, AS332L... approved by the aviation authority of France and are approved for operation in the United States. Pursuant...

  11. Complete Genome and Phylogeny of Puumala Hantavirus Isolates Circulating in France.

    PubMed

    Castel, Guillaume; Couteaudier, Mathilde; Sauvage, Frank; Pons, Jean-Baptiste; Murri, Séverine; Plyusnina, Angelina; Pontier, Dominique; Cosson, Jean-François; Plyusnin, Alexander; Marianneau, Philippe; Tordo, Noël

    2015-10-22

    Puumala virus (PUUV) is the agent of nephropathia epidemica (NE), a mild form of hemorrhagic fever with renal syndrome (HFRS) in Europe. NE incidence presents a high spatial variation throughout France, while the geographical distribution of the wild reservoir of PUUV, the bank vole, is rather continuous. A missing piece of the puzzle is the current distribution and the genetic variation of PUUV in France, which has been overlooked until now and remains poorly understood. During a population survey, from 2008 to 2011, bank voles were trapped in eight different forests of France located in areas known to be endemic for NE or in area from where no NE case has been reported until now. Bank voles were tested for immunoglobulin (Ig)G ELISA serology and two seropositive animals for each of three different areas (Ardennes, Jura and Orleans) were then subjected to laboratory analyses in order to sequence the whole S, M and L segments of PUUV. Phylogenetic analyses revealed that French PUUV isolates globally belong to the central European (CE) lineage although isolates from Ardennes are clearly distinct from those in Jura and Orleans, suggesting a different evolutionary history and origin of PUUV introduction in France. Sequence analyses revealed specific amino acid signatures along the N protein, including in PUUV from the Orleans region from where NE in humans has never been reported. The relevance of these mutations in term of pathophysiology is discussed.

  12. [Comparisons outpatient drug prescriptions: France, Denmark, Norway, Sweden].

    PubMed

    Dezileaux, Barbara; Martinez, Florie

    2016-06-01

    Comparisons outpatient drug prescriptions: France, Denmark, Norway, Sweden. Project compares quantitatively outpatient drug prescriptions in France, Denmark, Norway and Sweden. Data were obtained from national databases; the unit of measurement was defined daily dose per 1000 inhabitants. The five most prescribed drug classes were compared in each country in 2009, then benzodiazepines and antibiotics from 2006 to 2012. A literature review was focused on the context of prescriptions for each country. In 2009, the five most prescribed drug classes in the four countries represented seven classes in total. France was not the biggest prescriber of drugs, but from 2006 to 2012 benzodiazepines and antibiotics were prescribed much more in France than in the other countries. The evolution of prescriptions was different for each country, and very stable in France. In 2009, France was not the biggest drugs consumer of all classes, but was characterized by high prescriptions in some classes. Copyright © 2016 Société française de pharmacologie et de thérapeutique. Published by Elsevier Masson SAS. All rights reserved.

  13. Determinants of tetanus, diphtheria and poliomyelitis vaccinations among Hajj pilgrims, Marseille, France.

    PubMed

    Gautret, Philippe; Yong, Winnie; Soula, Georges; Parola, Philippe; Brouqui, Philippe; DelVecchio Good, Mary-Jo

    2010-08-01

    It has been observed that Muslim pilgrims departing France for Mecca have low national immunization rates against tetanus, diphtheria and poliomyelitis (TdP). Our purpose is to identify immigration, socio-economic and socio-cultural determinants of vaccination coverage against TdP. A cross-sectional survey study was conducted in late 2006 among 580 pilgrims in preparation who attended the Infectious and Tropical Medicine ward in Hôpital Nord at Marseille to receive their N. meningitidis vaccine required for travel to Mecca. Total vaccination rates for tetanus (18.9%), diphtheria (14.7%) and poliomyelitis (15.0%) were comparable. Pilgrim's characteristic lower socio-economic and social status, in addition to their unifying linguistic, cultural and religious identity defines them as a particularly disadvantageous group in France. French citizenship, higher level of education, better French fluency and no previous travel to country of origin were the strongest and most significant determinants of TdP vaccination status. These results suggest that the Muslim community in France is at risk from inequities of national preventive care efforts.

  14. Infiltrated bunch of solitons in Bi-doped frequency-shifted feedback fibre laser operated at 1450 nm

    PubMed Central

    Rissanen, Joona; Korobko, Dmitry A.; Zolotovsky, Igor O.; Melkumov, Mikhail; Khopin, Vladimir F.; Gumenyuk, Regina

    2017-01-01

    Mode-locked fibre laser as a dissipative system is characterized by rich forms of soliton interaction, which take place via internal energy exchange through noisy background in the presence of dispersion and nonlinearity. The result of soliton interaction was either stationary-localized or chaotically-oscillated soliton complexes, which have been shown before as stand-alone in the cavity. Here we report on a new form of solitons complex observed in Bi-doped mode-locked fibre laser operated at 1450 nm. The solitons are arranged in two different group types contemporizing in the cavity: one pulse group propagates as bound solitons with fixed phase relation and interpulse position eventuated in 30 dB spectrum modulation depth; while the other pulses form a bunch with continuously and chaotically moving solitons. The article describes both experimental and theoretical considerations of this effect. PMID:28281677

  15. [Involuntary psychiatric care for inmates in France: Only for "dangerous" patients?

    PubMed

    Fovet, T; Bertrand, M; Horn, M; Si Mohammed, W; Dandelot, D; Dalle, M-C; Thomas, P; Amad, A

    2017-11-27

    The unités hospitalières spécialement aménagées (UHSA) are full-time inpatient psychiatric units for inmates in France. Their creation has been associated with several advances in access to psychiatric care for inmates in recent years. However, there is still only one means of involuntary hospitalization for prisoners in France: care by decision of a representative of the state (les soins sur décision d'un représentant de l'état [SDRE]). Interestingly, for SDRE to be recognized as legal by the French judge, the patient must be "a danger to himself or to the others". Thus, there is a major difference with involuntary hospitalization outside the prison, and there are specific criteria for involuntary psychiatric hospitalization for inmates in France. This situation questions the general framework of involuntary psychiatric care and is very inconsistent with French law. Indeed, the goal of the loi n o  94-43 du 18 janvier 1994 relating to public health and social protection is to ensure equivalent care for all patients, incarcerated or not. Copyright © 2017 L'Encéphale, Paris. Published by Elsevier Masson SAS. All rights reserved.

  16. Particle-size reduction of Si3N4 powder with Si3N4 milling hardware

    NASA Technical Reports Server (NTRS)

    Herbell, T. P.; Freedman, M. R.; Kiser, J. D.

    1986-01-01

    The grinding of Si3N4 powder using reaction bonded Si3N4 attrition, vibratory, and ball mills with Si3N4 media was examined. The rate of particle size reduction and the change in the chemical composition of the powder were determined in order to compare the grinding efficiency and the increase in impurity content resulting from mill and media wear for each technique. Attrition and vibratory milling exhibited rates of specific surface area increase that were approximately eight times that observed in ball milling. Vibratory milling introduced the greatest impurity pickup.

  17. Sub-Saharan African migrants living with HIV acquired after migration, France, ANRS PARCOURS study, 2012 to 2013.

    PubMed

    Desgrées-du-Loû, Annabel; Pannetier, Julie; Ravalihasy, Andrainolo; Gosselin, Anne; Supervie, Virginie; Panjo, Henri; Bajos, Nathalie; Lert, France; Lydié, Nathalie; Dray-Spira, Rosemary

    2015-01-01

    We estimated the proportion of migrants from sub-Saharan Africa who acquired human immunodeficiency virus (HIV) while living in France. Life-event and clinical information was collected in 2012 and 2013 from a random sample of HIV-infected outpatients born in sub-Saharan Africa and living in the Paris region. We assumed HIV infection in France if at least one of the following was fulfilled: (i) HIV diagnosis at least 11 years after arrival in France, (ii) at least one negative HIV test in France, (iii) sexual debut after arrival in France. Otherwise, time of HIV infection was based on statistical modelling of first CD4(+) T-cell count; infection in France was assumed if more than 50% (median scenario) or more than 95% (conservative scenario) of modelled infection times occurred after migration. We estimated that 49% of 898 HIV-infected adults born in sub-Saharan Africa (95% confidence interval (CI): 45-53) in the median and 35% (95% CI: 31-39) in the conservative scenario acquired HIV while living in France. This proportion was higher in men than women (44% (95% CI: 37-51) vs 30% (95% CI: 25-35); conservative scenario) and increased with length of stay in France. These high proportions highlight the need for improved HIV policies targeting migrants.

  18. Dalitz plot analyses of J /ψ →π+π-π0, J /ψ →K+K-π0, and J /ψ →Ks0K±π∓ produced via e+e- annihilation with initial-state radiation

    NASA Astrophysics Data System (ADS)

    Lees, J. P.; Poireau, V.; Tisserand, V.; Grauges, E.; Palano, A.; Eigen, G.; Brown, D. N.; Kolomensky, Yu. G.; Fritsch, M.; Koch, H.; Schroeder, T.; Hearty, C.; Mattison, T. S.; McKenna, J. A.; So, R. Y.; Blinov, V. E.; Buzykaev, A. R.; Druzhinin, V. P.; Golubev, V. B.; Kravchenko, E. A.; Onuchin, A. P.; Serednyakov, S. I.; Skovpen, Yu. I.; Solodov, E. P.; Todyshev, K. Yu.; Lankford, A. J.; Gary, J. W.; Long, O.; Eisner, A. M.; Lockman, W. S.; Panduro Vazquez, W.; Chao, D. S.; Cheng, C. H.; Echenard, B.; Flood, K. T.; Hitlin, D. G.; Kim, J.; Miyashita, T. S.; Ongmongkolkul, P.; Porter, F. C.; Röhrken, M.; Huard, Z.; Meadows, B. T.; Pushpawela, B. G.; Sokoloff, M. D.; Sun, L.; Smith, J. G.; Wagner, S. R.; Bernard, D.; Verderi, M.; Bettoni, D.; Bozzi, C.; Calabrese, R.; Cibinetto, G.; Fioravanti, E.; Garzia, I.; Luppi, E.; Santoro, V.; Calcaterra, A.; de Sangro, R.; Finocchiaro, G.; Martellotti, S.; Patteri, P.; Peruzzi, I. M.; Piccolo, M.; Rotondo, M.; Zallo, A.; Passaggio, S.; Patrignani, C.; Lacker, H. M.; Bhuyan, B.; Szczepaniak, A. P.; Mallik, U.; Chen, C.; Cochran, J.; Prell, S.; Ahmed, H.; Pennington, M. R.; Gritsan, A. V.; Arnaud, N.; Davier, M.; Le Diberder, F.; Lutz, A. M.; Wormser, G.; Lange, D. J.; Wright, D. M.; Coleman, J. P.; Gabathuler, E.; Hutchcroft, D. E.; Payne, D. J.; Touramanis, C.; Bevan, A. J.; Di Lodovico, F.; Sacco, R.; Cowan, G.; Banerjee, Sw.; Brown, D. N.; Davis, C. L.; Denig, A. G.; Gradl, W.; Griessinger, K.; Hafner, A.; Schubert, K. R.; Barlow, R. J.; Lafferty, G. D.; Cenci, R.; Jawahery, A.; Roberts, D. A.; Cowan, R.; Robertson, S. H.; Dey, B.; Neri, N.; Palombo, F.; Cheaib, R.; Cremaldi, L.; Godang, R.; Summers, D. J.; Taras, P.; De Nardo, G.; Sciacca, C.; Raven, G.; Jessop, C. P.; LoSecco, J. M.; Honscheid, K.; Kass, R.; Gaz, A.; Margoni, M.; Posocco, M.; Simi, G.; Simonetto, F.; Stroili, R.; Akar, S.; Ben-Haim, E.; Bomben, M.; Bonneaud, G. R.; Calderini, G.; Chauveau, J.; Marchiori, G.; Ocariz, J.; Biasini, M.; Manoni, E.; Rossi, A.; Batignani, G.; Bettarini, S.; Carpinelli, M.; Casarosa, G.; Chrzaszcz, M.; Forti, F.; Giorgi, M. A.; Lusiani, A.; Oberhof, B.; Paoloni, E.; Rama, M.; Rizzo, G.; Walsh, J. J.; Smith, A. J. S.; Anulli, F.; Faccini, R.; Ferrarotto, F.; Ferroni, F.; Pilloni, A.; Piredda, G.; Bünger, C.; Dittrich, S.; Grünberg, O.; Heß, M.; Leddig, T.; Voß, C.; Waldi, R.; Adye, T.; Wilson, F. F.; Emery, S.; Vasseur, G.; Aston, D.; Cartaro, C.; Convery, M. R.; Dorfan, J.; Dunwoodie, W.; Ebert, M.; Field, R. C.; Fulsom, B. G.; Graham, M. T.; Hast, C.; Innes, W. R.; Kim, P.; Leith, D. W. G. S.; Luitz, S.; MacFarlane, D. B.; Muller, D. R.; Neal, H.; Ratcliff, B. N.; Roodman, A.; Sullivan, M. K.; Va'vra, J.; Wisniewski, W. J.; Purohit, M. V.; Wilson, J. R.; Randle-Conde, A.; Sekula, S. J.; Bellis, M.; Burchat, P. R.; Puccio, E. M. T.; Alam, M. S.; Ernst, J. A.; Gorodeisky, R.; Guttman, N.; Peimer, D. R.; Soffer, A.; Spanier, S. M.; Ritchie, J. L.; Schwitters, R. F.; Izen, J. M.; Lou, X. C.; Bianchi, F.; De Mori, F.; Filippi, A.; Gamba, D.; Lanceri, L.; Vitale, L.; Martinez-Vidal, F.; Oyanguren, A.; Albert, J.; Beaulieu, A.; Bernlochner, F. U.; King, G. J.; Kowalewski, R.; Lueck, T.; Nugent, I. M.; Roney, J. M.; Sobie, R. J.; Tasneem, N.; Gershon, T. J.; Harrison, P. F.; Latham, T. E.; Prepost, R.; Wu, S. L.; BaBar Collaboration

    2017-04-01

    We study the processes e+e- →γISRJ /ψ , where J /ψ →π+π-π0, J /ψ →K+K-π0, and J /ψ →KS0K±π∓ using a data sample of 519 fb-1 recorded with the BABAR detector operating at the SLAC PEP-II asymmetric-energy e+e- collider at center-of-mass energies at and near the Υ (n S ) (n =2 ,3 ,4 ) resonances. We measure the ratio of branching fractions R1=B/(J /ψ →K+K-π0) B (J /ψ →π+π-π0) and R2=B/(J /ψ →KS0K±π∓) B (J /ψ →π+π-π0) . We perform Dalitz plot analyses of the three J /ψ decay modes and measure fractions for resonances contributing to the decays. We also analyze the J /ψ →π+π-π0 decay using the Veneziano model. We observe structures compatible with the presence of ρ (1450 ) in all three J /ψ decay modes and measure the relative branching fraction: R (ρ (1450 ))=B/(ρ (1450 )→K+K-) B (ρ (1450 )→π+π-) =0.307 ±0.084 (stat)±0.082 (sys).

  19. Vocational Education and Training in France.

    ERIC Educational Resources Information Center

    Willems, Jean-Pierre

    This monograph gives an overview of the vocational education and training system in France. It contains the following information: (1) a presentation of the administrative, demographic, and economic background in which the training system in France exists; (2) a brief historical review of the development of the training systems; (3) a presentation…

  20. Recent Demographic Developments in France: Relatively Low Mortality at Advanced Ages

    PubMed Central

    Prioux, France; Barbieri, Magali

    2013-01-01

    France had 65.3 million inhabitants as of 1 January 2012, including 1.9 million in the overseas départements. The population is slightly younger than that of the European Union as a whole. Population growth continues at the same rate, mainly through natural increase. There are now more African than European immigrants living in France. Fertility was practically stable in 2011 (2.01 children per woman), but the lifetime fertility of the 1971–1972 cohorts reached a historic low in metropolitan France (1.99 children per woman), nevertheless remaining among the highest in Europe. Abortion levels remained stable and rates among young people are no longer increasing. The marriage rate is falling and the divorce rate has stabilized (46.2 divorces per 100 marriages in 2011). The risk of divorce decreases with age, but has greatly increased among the under-70s over the last decade. Life expectancy at birth (78.4 years for men, 85.0 for women) has continued to increase at the same rate, mainly thanks to progress at advanced ages. Among European countries, France has the lowest mortality in the over-65 age group, but it ranks less well for premature mortality. PMID:24285939

  1. 78 FR 60681 - Airworthiness Directives; Eurocopter France (Eurocopter) Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-02

    ... Airworthiness Directives; Eurocopter France (Eurocopter) Helicopters AGENCY: Federal Aviation Administration... helicopters have been approved by the aviation authority of France and are approved for operation in the United States. Pursuant to our bilateral agreement with France, EASA, its technical representative, has...

  2. Unusual structural phase transition in [N(C2H5)4][N(CH3)4][ZnBr4

    NASA Astrophysics Data System (ADS)

    Krawczyk, Monika K.; Ingram, Adam; Cach, Ryszard; Czapla, Zbigniew; Czupiński, Olaf; Dacko, Sławomir; Staniorowski, Piotr

    2018-04-01

    The new hybrid organic-inorganic crystal [N(C2H5)4][N(CH3)4][ZnBr4] was grown and its physical properties and structural phase transition are presented. On the basis of thermal analysis (DSC (differential scanning calorimetry), DTA (differential thermal analysis), DTG), X-ray structural, dilatometric and dielectric studies as well as optical observation, the reversible first-order phase transition at 490/488 K on heating and cooling run, respectively, has been found. An appearance of domain structure of ferroelastic type gives evidence for an untypical lowering of crystal symmetry during the phase transition. At room temperature, the satisfying crystal structure solution was found in the tetragonal system, in the P?21m space group.

  3. 78 FR 60188 - Airworthiness Directives; Eurocopter France (Eurocopter) Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-01

    ... Airworthiness Directives; Eurocopter France (Eurocopter) Helicopters AGENCY: Federal Aviation Administration... aviation authority of France and are approved for operation in the United States. Pursuant to our bilateral agreement with France, EASA, its technical representative, has notified us of the unsafe condition described...

  4. 78 FR 63853 - Airworthiness Directives; Eurocopter France (Eurocopter) Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-25

    ... Airworthiness Directives; Eurocopter France (Eurocopter) Helicopters AGENCY: Federal Aviation Administration... aviation authority of France and are approved for operation in the United States. Pursuant to our bilateral agreement with France, EASA, its technical representative, has notified us of the unsafe condition described...

  5. Characteristics of patients with fibromyalgia in France and Germany.

    PubMed

    Perrot, S; Winkelmann, A; Dukes, E; Xu, X; Schaefer, C; Ryan, K; Chandran, A; Sadosky, A; Zlateva, G

    2010-07-01

    Few studies have comprehensively assessed the burden associated with fibromyalgia (FM). This cross-sectional, observational study evaluates the impact of FM on patients in France and Germany. A total of 299 FM patients were recruited from 33 physician offices in France and Germany during routine visits. Patients completed a survey that included the Brief Pain Inventory-Short Form (BPI-sf), Fibromyalgia Impact Questionnaire (FIQ), EuroQol 5D (EQ-5D) and the Hospital Anxiety and Depression Scale (HADS) to describe their pain, FM and health-related quality of life (HRQOL). FM severity was defined using patients' FIQ total scores with 0 to < 39, 39 to < 59 and 59-100, representing mild, moderate and severe FM, respectively. Site staff completed case report forms using patients' medical records. Mean (standard deviation, SD) age was 54.2 (12.6); 81% of patients were women. The mean (SD) FIQ total score was 53.3 (19.6); 33% and 44% of patients reported moderate and severe FM, respectively. Most patients (91%) were receiving prescription medications for FM during the study. Patients reported a mean (SD) EQ-5D health state valuation of 0.44 (0.33) and a mean (SD) BPI-sf Pain Severity Index score of 4.9 (1.8). Forty-one percent of patients reported some level of disruption in their employment because of FM; employed patients missed a mean (SD) of 2.2 (4.6) workdays during the past 4 weeks. An increase in FM severity was significantly associated with increased pain severity, productivity loss, sleep disturbance and higher anxiety and depression (p < 0.0001). There is a substantial burden of illness including treatment limitations for FM patients in France and Germany.

  6. 77 FR 16137 - Airworthiness Directives; Eurocopter France Model Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-20

    ... Airworthiness Directives; Eurocopter France Model Helicopters AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for the Eurocopter France... directive (AD): 2012-05-01 Eurocopter France: Amendment 39-16973; Docket No. FAA- 2011-0454; Directorate...

  7. The quasar luminosity function at redshift 4 with the Hyper Suprime-Cam Wide Survey

    NASA Astrophysics Data System (ADS)

    Akiyama, Masayuki; He, Wanqiu; Ikeda, Hiroyuki; Niida, Mana; Nagao, Tohru; Bosch, James; Coupon, Jean; Enoki, Motohiro; Imanishi, Masatoshi; Kashikawa, Nobunari; Kawaguchi, Toshihiro; Komiyama, Yutaka; Lee, Chien-Hsiu; Matsuoka, Yoshiki; Miyazaki, Satoshi; Nishizawa, Atsushi J.; Oguri, Masamune; Ono, Yoshiaki; Onoue, Masafusa; Ouchi, Masami; Schulze, Andreas; Silverman, John D.; Tanaka, Manobu M.; Tanaka, Masayuki; Terashima, Yuichi; Toba, Yoshiki; Ueda, Yoshihiro

    2018-01-01

    We present the luminosity function of z ˜ 4 quasars based on the Hyper Suprime-Cam Subaru Strategic Program Wide layer imaging data in the g, r, i, z, and y bands covering 339.8 deg2. From stellar objects, 1666 z ˜ 4 quasar candidates are selected via the g-dropout selection down to i = 24.0 mag. Their photometric redshifts cover the redshift range between 3.6 and 4.3, with an average of 3.9. In combination with the quasar sample from the Sloan Digital Sky Survey in the same redshift range, a quasar luminosity function covering the wide luminosity range of M1450 = -22 to -29 mag is constructed. The quasar luminosity function is well described by a double power-law model with a knee at M1450 = -25.36 ± 0.13 mag and a flat faint-end slope with a power-law index of -1.30 ± 0.05. The knee and faint-end slope show no clear evidence of redshift evolution from those seen at z ˜ 2. The flat slope implies that the UV luminosity density of the quasar population is dominated by the quasars around the knee, and does not support the steeper faint-end slope at higher redshifts reported at z > 5. If we convert the M1450 luminosity function to the hard X-ray 2-10 keV luminosity function using the relation between the UV and X-ray luminosity of quasars and its scatter, the number density of UV-selected quasars matches well with that of the X-ray-selected active galactic nuclei (AGNs) above the knee of the luminosity function. Below the knee, the UV-selected quasars show a deficiency compared to the hard X-ray luminosity function. The deficiency can be explained by the lack of obscured AGNs among the UV-selected quasars.

  8. 78 FR 34960 - Airworthiness Directives; Eurocopter France Model Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-11

    ...-0501; Directorate Identifier 2011-SW-036-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France... rulemaking (NPRM). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France... Determination These helicopters have been approved by the aviation authority of France and are approved for...

  9. 78 FR 66668 - Airworthiness Directives; Eurocopter France (Eurocopter) Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-06

    ...-0938; Directorate Identifier 2012-SW-057-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France... Determination These helicopters have been approved by the aviation authority of France and are approved for operation in the United States. Pursuant to our bilateral agreement with France, EASA, its technical...

  10. 78 FR 33766 - Airworthiness Directives; Eurocopter France (Eurocopter) Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-05

    ...-0480; Directorate Identifier 2012-SW-090-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France... approved by the aviation authority of France and are approved for operation in the United States. Pursuant to our bilateral agreement with France, EASA, its technical representative, has notified us of the...

  11. A surgical sabbatical in France.

    PubMed

    Sutherland, F; Launois, B

    2000-06-01

    During my stay in France I had the unique opportunity to meet surgical professors from all over the world and made many friends and contacts in the field of hepatobiliary surgery. Brittany is a beautiful province of France, having unique way of life and approach to social and societal problems. The cultural enrichment that I received from my year there will last a lifetime, as well the many fond memories of the people, the culinary delights and the spectacular seashore.

  12. ELOVL4 protein preferentially elongates 20:5n3 to very long chain PUFAs over 20:4n6 and 22:6n3[S

    PubMed Central

    Yu, Man; Benham, Aaron; Logan, Sreemathi; Brush, R. Steven; Mandal, Md Nawajes A.; Anderson, Robert E.; Agbaga, Martin-Paul

    2012-01-01

    We hypothesized that reduction/loss of very long chain PUFAs (VLC-PUFAs) due to mutations in the ELOngase of very long chain fatty acid-4 (ELOVL4) protein contributes to retinal degeneration in autosomal dominant Stargardt-like macular dystrophy (STGD3) and age-related macular degeneration; hence, increasing VLC-PUFA in the retina of these patients could provide some therapeutic benefits. Thus, we tested the efficiency of elongation of C20-C22 PUFA by the ELOVL4 protein to determine which substrates are the best precursors for biosynthesis of VLC-PUFA. The ELOVL4 protein was expressed in pheochromocytoma cells, while green fluorescent protein-expressing and nontransduced cells served as controls. The cells were treated with 20:5n3, 22:6n3, and 20:4n6, either individually or in equal combinations. Both transduced and control cells internalized and elongated the supplemented FAs to C22-C26 precursors. Only ELOVL4-expressing cells synthesized C28-C38 VLC-PUFA from these precursors. In general, 20:5n3 was more efficiently elongated to VLC-PUFA in the ELOVL4-expressing cells, regardless of whether it was in combination with 22:6n3 or with 20:4n6. In each FA treatment group, C34 and C36 VLC-PUFAs were the predominant VLC-PUFAs in the ELOVL4-expressing cells. In summary, 20:5n3, followed by 20:4n6, seems to be the best precursor for boosting the synthesis of VLC-PUFA by ELOVL4 protein. PMID:22158834

  13. Beginning of Viniculture in France

    NASA Technical Reports Server (NTRS)

    McGovern, Patrick E.; Luley, Benjamin P.; Rovira, Nuria; Mirzoian, Armen; Callahan, Michael P.; Smith, Karen F.; Hall, Gretchen R.; Davidson, Theodore; Henkin, Joshua M.

    2013-01-01

    Chemical analyses of ancient organic compounds absorbed into the pottery fabrics of imported Etruscan amphoras (ca. 500-475 B.C.) and into a limestone pressing platform (ca. 425-400 B.C.) at the ancient coastal port site of Lattara in southern France provide the earliest biomolecular archaeological evidence for grape wine and viniculture from this country, which is crucial to the later history of wine in Europe and the rest of the world. The data support the hypothesis that export of wine by ship from Etruria in central Italy to southern Mediterranean France fueled an ever-growing market and interest in wine there, which, in turn, as evidenced by the winepress, led to transplantation of the Eurasian grapevine and the beginning of a Celtic industry in France. Herbal and pine resin additives to the Etruscan wine point to the medicinal role of wine in antiquity, as well as a means of preserving it during marine transport.

  14. Beginning of viniculture in France

    PubMed Central

    McGovern, Patrick E.; Luley, Benjamin P.; Rovira, Nuria; Mirzoian, Armen; Callahan, Michael P.; Smith, Karen E.; Hall, Gretchen R.; Davidson, Theodore; Henkin, Joshua M.

    2013-01-01

    Chemical analyses of ancient organic compounds absorbed into the pottery fabrics of imported Etruscan amphoras (ca. 500–475 B.C.) and into a limestone pressing platform (ca. 425–400 B.C.) at the ancient coastal port site of Lattara in southern France provide the earliest biomolecular archaeological evidence for grape wine and viniculture from this country, which is crucial to the later history of wine in Europe and the rest of the world. The data support the hypothesis that export of wine by ship from Etruria in central Italy to southern Mediterranean France fueled an ever-growing market and interest in wine there, which, in turn, as evidenced by the winepress, led to transplantation of the Eurasian grapevine and the beginning of a Celtic industry in France. Herbal and pine resin additives to the Etruscan wine point to the medicinal role of wine in antiquity, as well as a means of preserving it during marine transport. PMID:23733937

  15. Sources of Self-Efficacy: An Investigation of Elementary School Students in France

    ERIC Educational Resources Information Center

    Joet, Gwenaelle; Usher, Ellen L.; Bressoux, Pascal

    2011-01-01

    The purpose of this study was to assess the influence of Bandura's (1997) theorized sources of self-efficacy on the academic and self-regulatory efficacy beliefs of 3rd-grade elementary school students (N = 395) in France, to examine whether classroom context might explain a significant portion of the variation in self-efficacy, and to assess…

  16. The characterization of electroplex generated from the interface between 2-(4-trifluoromethyl-2-hydroxyphenyl)benzothiazole] zinc and N,N'-diphenyl-N,N'- bis(1-naphthyl)-(1,1'-biphenyl)-4,4'-diamine

    NASA Astrophysics Data System (ADS)

    Zhang, Ye; Hao, Yuying; Meng, Weixin; Xu, Huixia; Wang, Hua; Xu, Bingshe

    2012-03-01

    The electroplex between (2-(4-trifluoromethyl-2-hydroxyphenyl)benzothiazole) zinc [Zn(4-TfmBTZ)2] as an electron-acceptor and N,N'-diphenyl-N,N'-bis(1-naphthyl)-(1,1'-biphenyl)-4,4'-diamine (NPB) as an electron-donor was characterized by bilayer, blend, and multilayer quantum-well (MQW) device, respectively. The blend composition and quantum-well number are effective parameters for tuning electroluminescence color. White light with high color purity and color rendering index (CRI) was observed from these devices based on Zn(4-TfmBTZ)2/NPB. Moreover, the blend and MQW devices all exhibit high operation stability, hence excellent color stability. For the device with 5 mol% NPB in blend layer, its Commission International Del'Eclairage (CIE) coordinate region is x=0.28-0.31, y=0.33-0.35 and CRI is 83.3-91.2 at 5-9 V. For MQW structure device with NPB of 60 nm thickness, its CIE coordinate region is x=0.29-0.32, y=0.31-0.34 and CRI=87.9-92.5 at 10-15 V. Such high color stability and purity and CRI, being close to ideal white light, are of current important for white OLED.

  17. catena-Poly[[bis­[4-(dimethyl­amino)­pyridine-κN 1]cobalt(II)]-di-μ-azido-κ4 N 1:N 3

    PubMed Central

    Guenifa, Fatiha; Zeghouan, Ouahida; Hadjadj, Nasreddine; Bendjeddou, Lamia; Merazig, Hocine

    2013-01-01

    The title layered polymer, [Co(N3)2(C7H10N2)2]n, contains CoII, azide and 4-(dimethyl­amino)­pyridine (4-DMAP) species with site symmetries m2m, 2 and m, respectively. The Co2+ ion adopts an octa­hedral coordination geometry in which four N atoms from azide ligands lie in the equatorial plane and two 4-DMAP N atoms occupy the axial positions. The CoII atoms are connected by two bridging azide ligands, resulting in a chain parallel to the c axis. PMID:23476514

  18. 78 FR 49115 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-13

    ... Airworthiness Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA), DOT... published in the Federal Register. The AD applies to certain Eurocopter France (Eurocopter) Model AS350B3...

  19. 75 FR 39277 - Sorbitol From France; Determination

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-08

    ... INTERNATIONAL TRADE COMMISSION [Investigation No. 731-TA-44 (Third Review)] Sorbitol From France... U.S.C. 1675d(c)) (the Act), that revocation of the antidumping duty order on sorbitol from France... views of the Commission are contained in USITC Publication 4164 (June 2010), entitled Sorbitol from...

  20. The response of medical virology laboratories to the influenza A(H1N1)pdm09 outbreak in Paris Île-de-France region.

    PubMed

    Seringe, E; Agut, H

    2013-10-01

    The outbreak of influenza A(H1N1)pdm09 was a challenge for the laboratories of Paris Île-de-France region in charge of virological diagnosis. In order to evaluate the quality of their response to this challenge, a retrospective survey based on a self-administered standardized questionnaire was undertaken among the 18 hospital laboratories involved in A(H1N1)pdm09 virus detection over a period of 10 months from April 2009 to January 2010. All concerned laboratories responded to the survey. Due to imposed initial biosafety constraints and indications, virological diagnosis was performed in only two laboratories at the start of the studied period. Step by step, it was further settled in the other laboratories starting from June to November 2009. From the beginning, A(H1N1)pdm09-specific RT-PCR was considered the reference method while the use of rapid influenza detection tests remained temporary and concerned a minority of these laboratories. Among the overall 21,656 specimens received, a positive diagnosis of influenza A(H1N1)pdm09 was obtained in 5,390 cases (25%), the positivity range being significantly higher among women as compared to men (P<0.0001) and subjects below 45 years of age as compared to those over 65 years (P<0.0001). Two peaks in positivity frequency were observed at weeks 24 (30%, 8-12 June 2009) and 44 (50%, 26-30 October 2009) respectively, the latter one occurring 2 weeks earlier than the peak of epidemic at the national level. In contrast, a low positivity rate was detected at weeks 38-40 in relationship with other respiratory virus infections which were clinically misinterpreted as a peak of influenza epidemic. These data demonstrate the ability of medical virology laboratories of Paris Île-de-France region to provide in real time a valuable diagnosis of A(H1N1)pdm09 virus infection and a relevant view of outbreak evolution, suggesting they will be a crucial component in the management of future influenza epidemics. Copyright © 2012

  1. Patterns of adjuvant chemotherapy for stage II and III colon cancer in France and Italy.

    PubMed

    Bouvier, Anne-Marie; Minicozzi, Pamela; Grosclaude, Pascale; Bouvier, Véronique; Faivre, Jean; Sant, Milena

    2013-08-01

    European guidelines recommend adjuvant chemotherapy for stage III colon cancer but not for stage II. To determine the extent to which adjuvant chemotherapy was used in Italy and France. A common retrospective database of 2186 colon cancers diagnosed between 2003 and 2005 was analysed according to age, stage and presenting features. 38.9% of patients with stage II and 64.6% with stage III received chemotherapy in Italy, 21.7% and 65.1% in France. For stage II, the association between country and chemotherapy was only significant in patients diagnosed out of emergency (ORItaly/France: 3.05 [2.12-4.37], p<0.001) whereas patients diagnosed in emergency were as likely to receive chemotherapy in both countries. For stage III, there was a trend to a higher administration of chemotherapy for elderly patients in France compared to Italy. French patients were more likely than Italian to receive chemotherapy (OR: 1.91[1.32-2.78], p=0.001). Chemotherapy for stage III colon cancer was as extensively used in Italy as in France for young patients. Its administration could be increased in patients over 75. Stage II patients with a lower risk of relapse received chemotherapy more often in Italy than in France. Copyright © 2013 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.

  2. Hydride vapor phase epitaxy of AlN using a high temperature hot-wall reactor

    NASA Astrophysics Data System (ADS)

    Baker, Troy; Mayo, Ashley; Veisi, Zeinab; Lu, Peng; Schmitt, Jason

    2014-10-01

    Aluminum nitride (AlN) was grown on c-plane sapphire substrates by hydride vapor phase epitaxy (HVPE). The experiments utilized a two zone inductively heated hot-wall reactor. The surface morphology, crystal quality, and growth rate were investigated as a function of growth temperature in the range of 1450-1575 °C. AlN templates grown to a thickness of 1 μm were optimized with double axis X-ray diffraction (XRD) rocking curve full width half maximums (FWHMs) of 135″ for the (002) and 513″ for the (102).

  3. Seoul Virus Infection in Humans, France, 2014–2016

    PubMed Central

    Carli, Damien; Bour, Jean-Baptiste; Boudjeltia, Samir; Dewilde, Anny; Gerbier, Guillaume; Nussbaumer, Timothée; Jacomo, Véronique; Rapt, Marie-Pierre; Rollin, Pierre E.; Septfons, Alexandra

    2017-01-01

    We report detection of Seoul virus in 3 patients in France over a 2-year period. These patients accounted for 3 of the 4 Seoul virus infections among 434 hantavirus infections (1.7%) reported during this time. More attention should be given to this virus in Europe where surveillance has been focused mostly on Puumala and Dobrava-Belgrade hantaviruses. PMID:28368241

  4. Reliability and validity of the French-Canadian version of the scoliosis research society 22 questionnaire in France.

    PubMed

    Lonjon, Guillaume; Ilharreborde, Brice; Odent, Thierry; Moreau, Sébastien; Glorion, Christophe; Mazda, Keyvan

    2014-01-01

    Outcome study to determine the internal consistency, reproducibility, and concurrent validity of the French-Canadian version of the Scoliosis Research Society 22 (SRS-22 fcv) patient questionnaire in France. To determine whether the SRS-22 fcv can be used in a population from France. The SRS-22 has been translated and validated in multiple countries, notably in the French-Canadian language in Quebec, Canada. Use of SRS-22 fcv seems appropriate for evaluating adolescent idiopathic scoliosis in France. However, French-Canadian French is noticeably different from the French spoken in France, and no study has investigated the use of a French-Canadian version of a health-quality questionnaire in another French population. The methods used for validating the SRS-22 fcv in Quebec were adopted for use with a group of 200 adolescents with idiopathic scoliosis and 60 healthy adolescents in France. Reliability and reproducibility were measured by the Cronbach α and intraclass correlation coefficient (ICC), construct validity by factorial analysis, concurrent validity by the Short-Form of the survey, and discriminant validity by analysis of variance and multivariate linear regression. In France, the SRS-22 fcv showed good global internal consistency (Cronbach α = 0.87, intraclass correlation coefficient = 0.92), a coherent factorial structure, and high correlation coefficients between the SRS-22 fcv and Short-Form of the survey (P < 0.001). However, reliability and validity were slightly less than that for the instrument's original validation and the validation of the SRS-22 fcv in Quebec. These differences could be explained by language and cultural differences. The SRS-22 fcv is relevant for use in France, but further development and validation of a specific French questionnaire remain necessary to improve the assessment of functional outcomes of adolescents with scoliosis in France. N/A.

  5. N(4)-Methyl-N(4)-(2-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine-ethanol-hydrazine (1/0.865/0.135): hydrogen-bonded ribbons containing four independent ring types.

    PubMed

    Trilleras, Jorge; Quiroga, Jairo; Cobo, Justo; Glidewell, Christopher

    2009-06-01

    N(4)-Methyl-N(4)-(2-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine crystallizes from ethanol as a mixed solvate, C(13)H(14)N(6).0.865C(2)H(6)O.0.135N(2)H(4), (I), where the hydrazine has been carried through from the initial preparation. Within the heterocyclic component, the 2-methylphenyl substituent is disordered over two sets of sites. There is an intramolecular C-H...pi(arene) hydrogen bond, which may control the molecular conformation of the heterocycle. The heterocyclic molecules are linked by two independent N-H...N hydrogen bonds in a chain containing two types of R(2)(2)(8) ring. The ethanol component is linked to this chain by a combination of O-H...N and N-H...O hydrogen bonds and the hydrazine component by two N-H...N hydrogen bonds, so generating two R(3)(3)(9) rings and thus forming a ribbon containing four distinct ring types.

  6. Uranium mining in France

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    White, L.

    Since the onset of the first ''oil shock'' in 1974, France has pursued a policy of steadily increasing energy independence based on nuclear power for generation of electricity. In 1973, nuclear reactors supplied only 8% of France's electrical power. A strong development effort lifted the nuclear share to 23% in 1980, to 66% in 1985, and the plan is to raise the total to 75% by 1990. In 1976, Cogema (Compagnie Generale des Matieres Nucleaires) was organized from the production division of France's Commissariat a l'Energie Atomique (CEA) to handle fuel supply and spent fuel reprocessing for the expanding industrymore » (see subsequent article on Cogema). In parallel with growth of the French nuclear power, Cogema has become a world leader in all aspects of the fuel cycle, providing services not only domestically but internationally as well. As a uranium mining company, Cogema has steadily developed domestic and foreign sources of supply, and over the years it has maintained the world's strongest uranium exploration effort throughout the ups and downs of the market. As a result, the company has become the world's leading uranium supplier, with about 20% of total production contributed either by its domestic mining divisions or overseas subsidiaries.« less

  7. Multielectron spectroscopy: energy levels of K n+ and Rb n+ ions (n = 2, 3, 4)

    NASA Astrophysics Data System (ADS)

    Khalal, M. A.; Soronen, J.; Jänkälä, K.; Huttula, S.-M.; Huttula, M.; Bizau, J.-M.; Cubaynes, D.; Guilbaud, S.; Ito, K.; Andric, L.; Feng, J.; Lablanquie, P.; Palaudoux, J.; Penent, F.

    2017-11-01

    A magnetic bottle time-of-flight spectrometer has been used to perform spectroscopy of K n+ and Rb n+ states with ionization degrees n of 2, 3 and 4. Energy levels are directly measured by detecting in coincidence the n electrons that are emitted as a result of single photon absorption. Experimental results are compared with the energies from the NIST atomic database and ab initio multiconfiguration Dirac-Fock calculations. Previously unidentified 3p 4(3P)3d 1 4D energy levels of K2+ are assigned.

  8. The crystal structures of iron and cobalt pyridine (py)–sulfates, [Fe(SO4)(py)4]n and [Co3(SO4)3(py)11]n

    PubMed Central

    Pham, Duyen N. K.; Roy, Mrittika; Kreider-Mueller, Ava; Golen, James A.; Manke, David R.

    2018-01-01

    The solid-state structures of two metal–pyridine–sulfate compounds, namely catena-poly[[tetra­kis­(pyridine-κN)iron(II)]-μ-sulfato-κ2 O:O′], [Fe(SO4)(C5H5N)4]n, (1), and catena-poly[[tetra­kis­(pyridine-κN)cobalt(II)]-μ-sulfato-κ2 O:O′-[tetra­kis­(pyridine-κN)cobalt(II)]-μ-sulfato-κ3 O,O′:O′′-[tris­(pyridine-κN)cobalt(II)]-μ-sulfato-κ2 O:O′], [Co3(SO4)3(C5H5N)11]n, (2), are reported. The iron compound (1) displays a polymeric structure, with infinite chains of FeII atoms adopting octa­hedral N4O2 coordination environments that involve four pyridine ligands and two bridging sulfate ligands. The cobalt compound (2) displays a polymeric structure, with infinite chains of CoII atoms. Two of the three Co centers have an octa­hedral N4O2 coordination environment that involves four pyridine ligands and two bridging sulfate ligands. The third Co center has an octa­hedral N3O3 coordination environment that involves three pyridine ligands, and two bridging sulfate ligands with one sulfate chelating the cobalt atom.

  9. Inside France: Three Missing Pages from Your Students' Textbook.

    ERIC Educational Resources Information Center

    Conniffe, Patricia, Ed.

    This mini-unit seeks to fill the gap in textbooks that exists when teaching about modern France. Many textbooks end their coverage of France with the chapter on World War II. This unit offers high school students a unique introduction to France in the mid-1990s. The mini-unit includes a two-sided poster, teaching tips, and student pages. Student…

  10. Gambling and gambling-related problems in France.

    PubMed

    Valleur, Marc

    2015-12-01

    To provide an overview of the gambling landscape and gambling-related problems in France, including the history, legislation, gambling policy and epidemiological data on excessive gambling. A literature review, using Medline, PsycInfo and Toxibase/OFDT databases, based on the systematic monitoring of scientific literature since 2008 (including French and international papers). Since 1776 and the creation of the royal lottery, state monopoly has been the main pillar of gambling policy in France. Increases in gambling venues and opportunities, growing evidence of gambling-related problems, pressures from the European Commission and the growth of on-line gambling have led to major changes in this policy: while land-based gambling remains mainly in the form of a state monopoly, on-line gambling was partially liberalized in 2010, and regulation authorities were established. The first epidemiological survey was conducted in 2010. Rates of problematic gambling in France are within the average of other European countries. Treatment has begun to be made available within addiction centres. A majority of on-line gamblers in France use legal websites, which was one of the initial goals of liberalization. Recent studies confirm that the prevalence of problem gambling in France is far higher among on-line gamblers than among land-based gamblers; however, this difference cannot be attributed only to greater addictiveness of on-line gambling. © 2015 Society for the Study of Addiction.

  11. Dalitz plot analyses of J / ψ → π + π - π 0 , J / ψ → K + K - π 0 , and J / ψ → K s 0 K ± π ∓ produced via e + e - annihilation with initial-state radiation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lees, J. P.; Poireau, V.; Tisserand, V.

    Here, we study the processes e +e - → γ ISR J/ψ , where J/ψ → π +π -π 0, J/ψ → K +K -π 0 , and J / ψ → Kmore » $$0\\atop{S}$$ K ± π ∓ using a data sample of 519 fb -1 recorded with the BABAR detector operating at the SLAC PEP-II asymmetric-energy e +e - collider at center-of-mass energies at and near the Υ (nS) (n = 2 , 3 , 4) resonances. We measure the ratio of branching fractions R 1 = $$B(J/ψ →K^+K^- π^0)\\atop{B(J/ψ →π^+π^- π^0)}$$ and R 2= $$B(J/ψ →K^0_SK^±π^∓)\\atop{B(J/ψ →π^+π^- π^0)}$$. We perform Dalitz plot analyses of the three J/ψ decay modes and measure fractions for resonances contributing to the decays. We also analyze the J/ψ → $π^+π^- π^0$ decay using the Veneziano model. We observe structures compatible with the presence of ρ (1450) in all three J/ψ decay modes and measure the relative branching fraction: R (p(1450)) = $$Bp(1450)→K^+K^-)\\atop{B(p(1450)→π^+π^-)}$$ +0.307 ± 0.084 (stat) ± 0.082 (sys).« less

  12. Dalitz plot analyses of J / ψ → π + π - π 0 , J / ψ → K + K - π 0 , and J / ψ → K s 0 K ± π ∓ produced via e + e - annihilation with initial-state radiation

    DOE PAGES

    Lees, J. P.; Poireau, V.; Tisserand, V.; ...

    2017-04-10

    Here, we study the processes e +e - → γ ISR J/ψ , where J/ψ → π +π -π 0, J/ψ → K +K -π 0 , and J / ψ → Kmore » $$0\\atop{S}$$ K ± π ∓ using a data sample of 519 fb -1 recorded with the BABAR detector operating at the SLAC PEP-II asymmetric-energy e +e - collider at center-of-mass energies at and near the Υ (nS) (n = 2 , 3 , 4) resonances. We measure the ratio of branching fractions R 1 = $$B(J/ψ →K^+K^- π^0)\\atop{B(J/ψ →π^+π^- π^0)}$$ and R 2= $$B(J/ψ →K^0_SK^±π^∓)\\atop{B(J/ψ →π^+π^- π^0)}$$. We perform Dalitz plot analyses of the three J/ψ decay modes and measure fractions for resonances contributing to the decays. We also analyze the J/ψ → $π^+π^- π^0$ decay using the Veneziano model. We observe structures compatible with the presence of ρ (1450) in all three J/ψ decay modes and measure the relative branching fraction: R (p(1450)) = $$Bp(1450)→K^+K^-)\\atop{B(p(1450)→π^+π^-)}$$ +0.307 ± 0.084 (stat) ± 0.082 (sys).« less

  13. How do general practitioners put preventive care recommendations into practice? A cross-sectional study in Switzerland and France.

    PubMed

    Sebo, Paul; Cerutti, Bernard; Fournier, Jean-Pascal; Rat, Cédric; Rougerie, Fabien; Senn, Nicolas; Haller, Dagmar M; Maisonneuve, Hubert

    2017-10-06

    We previously identified that general practitioners (GPs) in French-speaking regions of Europe had a variable uptake of common preventive recommendations. In this study, we describe GPs' reports of how they put different preventive recommendations into practice. Cross-sectional study conducted in 2015 in Switzerland and France. 3400 randomly selected GPs were asked to complete a postal (n=1100) or online (n=2300) questionnaire. GPs who exclusively practiced complementary and alternative medicine were not eligible for the study. 764 GPs (response rate: postal 47%, online 11%) returned the questionnaire (428 in Switzerland and 336 in France). We investigated how the GPs performed five preventive practices (screening for dyslipidaemia, colorectal and prostate cancer, identification of hazardous alcohol consumption and brief intervention), examining which age group they selected, the screening frequency, the test they used, whether they favoured shared decision for prostate cancer screening and their definition of hazardous alcohol use. A large variability was observed in the way in which GPs provide these practices. 41% reported screening yearly for cholesterol, starting and stopping at variable ages. 82% did not use any test to identify hazardous drinking. The most common responses for defining hazardous drinking were, for men, ≥21 drinks/week (24%) and ≥4 drinks/occasion for binge drinking (20%), and for women, ≥14 drinks/week (28%) and ≥3 drinks/occasion (21%). Screening for colorectal cancer, mainly with colonoscopy in Switzerland (86%) and stool-based tests in France (93%), was provided every 10 years in Switzerland (65%) and 2 years in France (91%) to patients between 50 years (87%) and 75 years (67%). Prostate cancer screening, usually with shared decision (82%), was provided yearly (62%) to patients between 50 years (74%) and 75-80 years (32%-34%). The large diversity in the way these practices are provided needs to be addressed, as it could

  14. [Costs of healthcare resource consumption after a myocardial infarction in France: An estimate from a medicoadministrative database (GSB)].

    PubMed

    Philippe, F; Blin, P; Bouée, S; Laurendeau, C; Torreton, E; Gourmelin, J; Velkovski-Rouyer, M; Levy-Bachelot, L; Steg, G

    2017-04-01

    To estimate the costs of healthcare resource consumption in the year preceding and the year following a myocardial infarction (MI). A historical cohort of patients experiencing an MI in France between 2007 and 2011 was extracted from the échantillon généraliste de bénéficiaires, a 1/97th sample of all beneficiaries of public health insurance in France. A total of 1920 patients experiencing an MI were identified. Two-thirds were men and the mean age was 67 years; 20.6% had diabetes, 37.6% hypercholesterolaemia and 82.4% hypertension. From a societal perspective, the annual costs of medical consumption related to hospitalisations increased from € 4548 before the MI to € 6470 in the following year. Costs of community care rose from € 2932 to € 6208. This increase concerned all components of community healthcare: costs associated with medical transportation increased fourfold, those associated with consultations and laboratory tests tripled, medication costs doubled and costs of paramedical services also increased, but to a lesser extent. It should be noted that the cost of hospitalisation for the index MI (€ 5876) is not included in the above costs. From a society perspective, the cost of healthcare resource consumption increased threefold in the year following an MI. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

  15. Mechanism of the mutagenic action of hydroxylamine. IX. The UV-induced cleavage of the N-O bond in N4-hydroxy-and N4-methoxycytidine and N6-methoxyadenosine.

    PubMed Central

    Simukova, N A; Yakovlev, D Y; Budowsky, E I

    1975-01-01

    The principal UV-induced (lambda = 2546nm) reaction of N4-hydroxy- and N4methoxycytidines and N6-methoxyadenosine in neutral aqueous solutions is cleavage of the exocyclic N-O bond with the respective formation of cytidine and adenosine. Quantum yields are 2.8x10(-3) and 2.2x10(-3) M/E for the first two compounds and 9.1x10(-3) M/E for N6-methoxyadenosine. PMID:1052542

  16. Obsidian in the Casas Grandes world: Procurement, exchange, and interaction in Chihuahua, Mexico, CE 1200-1450

    DOE PAGES

    Dolan, Sean Gregory; Whalen, Michael E.; Minnis, Paul E.; ...

    2017-01-09

    The Casas Grandes area in Chihuahua, Mexico and the site of Paquime was the center of one the largest regional systems in the U.S. Southwest and Mexican Northwest (SW/NW) during the Medio period (CE 1200-1450). People participated in local and distant exchange networks with groups in the SW/NW, Mesoamerica, and West Mexico. Our knowledge of which obsidian sources people used in Casas Grandes is limited, despite how obsidian could have derived from many different places. We examine how the use of specific obsidian sources may relate to broader political and economic relationships within the Casas Grandes regional system and itsmore » association with the Mimbres and Animas regions of the SW/NW. We sourced 116 artifacts using EDXRF spectrometry from four sites that neighbor Paquime. Results demonstrate people used obsidian from Chihuahua, Sonora, and New Mexico. Furthermore, there were varying levels of social interaction and regional integration because there is diversity in source use at the site level, and Casas Grandes were more connected to the Animas region than Mimbres regarding obsidian resource procurement.« less

  17. Obsidian in the Casas Grandes world: Procurement, exchange, and interaction in Chihuahua, Mexico, CE 1200-1450

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dolan, Sean Gregory; Whalen, Michael E.; Minnis, Paul E.

    The Casas Grandes area in Chihuahua, Mexico and the site of Paquime was the center of one the largest regional systems in the U.S. Southwest and Mexican Northwest (SW/NW) during the Medio period (CE 1200-1450). People participated in local and distant exchange networks with groups in the SW/NW, Mesoamerica, and West Mexico. Our knowledge of which obsidian sources people used in Casas Grandes is limited, despite how obsidian could have derived from many different places. We examine how the use of specific obsidian sources may relate to broader political and economic relationships within the Casas Grandes regional system and itsmore » association with the Mimbres and Animas regions of the SW/NW. We sourced 116 artifacts using EDXRF spectrometry from four sites that neighbor Paquime. Results demonstrate people used obsidian from Chihuahua, Sonora, and New Mexico. Furthermore, there were varying levels of social interaction and regional integration because there is diversity in source use at the site level, and Casas Grandes were more connected to the Animas region than Mimbres regarding obsidian resource procurement.« less

  18. 78 FR 47230 - Airworthiness Directives; Eurocopter France (Eurocopter) Model Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-05

    ...-0679; Directorate Identifier 2009-SW-015-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France... aviation authority of France and are approved for operation in the United States. Pursuant to our bilateral agreement with France, EASA, its technical representative, has notified us of the unsafe condition described...

  19. Direct medical costs associated with the extrahepatic manifestations of hepatitis C virus infection in France.

    PubMed

    Cacoub, P; Vautier, M; Desbois, A C; Saadoun, D; Younossi, Z

    2018-01-01

    The economic impact of extrahepatic manifestations of hepatitis C virus (HCV) infection remains unknown for France. To estimate the prevalence of extrahepatic manifestations of HCV and the direct medical costs associated with them. Estimates of 13 extrahepatic manifestations prevalence were obtained from (1) a retrospective data analysis of HCV-infected patients in a specialised centre and the baseline prevalence in the general French population and (2) an international systematic review. Per-patient-per-year costs to treat these manifestations were obtained from the literature, national databases or expert opinion. The impact of achieving HCV cure after anti-viral therapy was applied to the French healthcare costs. Using approach (1), increased prevalence rates in HCV patients compared to the general population were observed for most extrahepatic manifestations. The mean per-patient-per-year cost of these manifestations in the tertiary centre was 3296 € [95% CI 1829; 5540]. In France, HCV-extrahepatic manifestations amounted to a total cost of 215 million (M) € per year [144; 299]. Using approach (2), the mean per-patient-per-year cost was estimated to be 1117 €. The estimated total cost reduction in France associated with HCV cure was 13.9 M€ for diabetes, 8.6 M€ for cryoglobulinemia vasculitis, 6.7 M€ for myocardial infarction, 2.4 M€ for end-stage renal disease and 1.4 M€ for stroke. Extrahepatic manifestations of HCV infection substantially add to the overall economic burden of the disease in France. HCV cure after anti-viral therapy is expected to significantly reduce the total costs of managing these manifestations in France. © 2017 John Wiley & Sons Ltd.

  20. Novel N4 Bacteriophages Prevail in the Cold Biosphere.

    PubMed

    Zhan, Yuanchao; Buchan, Alison; Chen, Feng

    2015-08-01

    Coliphage N4 is a lytic bacteriophage discovered nearly half a century ago, and it was considered to be a "genetic orphan" until very recently, when several additional N4-like phages were discovered to infect nonenteric bacterial hosts. Interest in this genus of phages is stimulated by their unique genetic features and propagation strategies. To better understand the ecology of N4-like phages, we investigated the diversity and geographic patterns of N4-like phages by examining 56 Chesapeake Bay viral communities, using a PCR-clone library approach targeting a diagnostic N4-like DNA polymerase gene. Many new lineages of N4-like phages were found in the bay, and their genotypes shift from the lower to the upper bay. Interestingly, signature sequences of N4-like phages were recovered only from winter month samples, when water temperatures were below 4°C. An analysis of existing metagenomic libraries from various aquatic environments supports the hypothesis that N4-like phages are most prolific in colder waters. In particular, a high number of N4-like phages were detected in Organic Lake, Antarctica, a cold and hypersaline system. The prevalence of N4-like phages in the cold biosphere suggests these viruses possess yet-to-be-determined mechanisms that facilitate lytic infections under cold conditions. Copyright © 2015, American Society for Microbiology. All Rights Reserved.

  1. Ceftriaxone-Resistant Salmonella enterica Serotype Newport, France

    PubMed Central

    Egorova, Svetlana; Timinouni, Mohammed; Demartin, Marie; Granier, Sophie A.; Whichard, Jean M.; Sangal, Vartul; Fabre, Laëtitia; Delauné, Aurélia; Pardos, Maria; Millemann, Yves; Espié, Emmanuelle; Achtman, Mark; Grimont, Patrick A.D.

    2008-01-01

    The multidrug-resistant (MDR) Salmonella enterica serotype Newport strain that produces CMY-2 β-lactamase (Newport MDR-AmpC) was the source of sporadic cases and outbreaks in humans in France during 2000–2005. Because this strain was not detected in food animals, it was most likely introduced into France through imported food products. PMID:18507913

  2. Ab Initio Calculations of Anharmonic Vibrational Spectroscopy for Hydrogen Fluoride (HF)n (n=3,4) and Mixed Hydrogen Fluoride/Water (HF)n(H20)n (n=1,2,4) Clusters

    NASA Technical Reports Server (NTRS)

    Chaban, Galina M.; Gerber, R. Benny; Kwak, Dochan (Technical Monitor)

    2001-01-01

    Anharmonic vibrational frequencies and intensities are computed for hydrogen fluoride clusters (HF)n with n=3,4 and mixed clusters of hydrogen fluoride with water (HF)n(H2O)n where n=1,2. For the (HF)4(H2O)4 complex, the vibrational spectra are calculated at the harmonic level, and anharmonic effects are estimated. Potential energy surfaces for these systems are obtained at the MP2/TZP level of electronic structure theory. Vibrational states are calculated from the potential surface points using the correlation-corrected vibrational self-consistent field (CC-VSCF) method. The method accounts for the anharmonicities and couplings between all vibrational modes and provides fairly accurate anharmonic vibrational spectra that can be directly compared with experimental results without a need for empirical scaling. For (HF)n, good agreement is found with experimental data. This agreement shows that the MP2 potential surfaces for these systems are reasonably reliable. The accuracy is best for the stiff intramolecular modes, which indicates the validity of MP2 in describing coupling between intramolecular and intermolecular degrees of freedom. For (HF)n(H2O)n experimental results are unavailable. The computed intramolecular frequencies show a strong dependence on cluster size. Intensity features are predicted for future experiments.

  3. Genetic characterization of avian influenza subtype H4N6 and H4N9 from live bird market, Thailand

    USDA-ARS?s Scientific Manuscript database

    A one year active surveillance program for influenza A viruses among avian species in a live-bird market (LBM) in Bangkok, Thailand was conducted in 2009. Out of 970 samples collected, influenza A virus subtypes H4N6 (n=2) and H4N9 (n=1), were isolated from healthy Muscovy ducks. All three viruses w...

  4. Aging in France: Population Trends, Policy Issues, and Research Institutions

    ERIC Educational Resources Information Center

    Beland, Daniel; Durandal, Jean-Philippe Viriot

    2013-01-01

    Like in other advanced industrial countries, in France, demographic aging has become a widely debated research and policy topic. This article offers a brief overview of major aging-related trends in France. The article describes France's demographics of aging, explores key policy matters, maps the institutional field of French social gerontology…

  5. Estimating the budget impact of orphan drugs in Sweden and France 2013-2020.

    PubMed

    Hutchings, Adam; Schey, Carina; Dutton, Richard; Achana, Felix; Antonov, Karolina

    2014-02-13

    The growth in expenditure on orphan medicinal products (OMP) across Europe has been identified as a concern. Estimates of future expenditure in Europe have suggested that OMPs could account for a significant proportion of total pharmaceutical expenditure in some countries, but few of these forecasts have been well validated. This analysis aims to establish a robust forecast of the future budget impact of OMPs on the healthcare systems in Sweden and France. A dynamic forecasting model was created to estimate the budget impact of OMPs in Sweden and France between 2013 and 2020. The model used historical data on OMP designation and approval rates to predict the number of new OMPs coming to the market. Average OMP sales were estimated for each year post-launch by regression analysis of historical sales data. Total forecast sales were compared with expected sales of all pharmaceuticals in each country to quantify the relative budget impact. The model predicts that by 2020, 152 OMPs will have marketing authorization in Europe. The base case OMP budget impacts are forecast to grow from 2.7% in Sweden and 3.2% in France of total drug expenditure in 2013 to 4.1% in Sweden and 4.9% in France by 2020. The principal driver of expenditure growth is the number of new OMPs obtaining OMP designation. This is tempered by the slowing success rate for new approvals and the loss of intellectual property protection on existing orphan medicines. Given the forward-looking nature of the analysis, uncertainty exists around model parameters and sensitivity analysis found peak year budget impact varying between 2% and 11%. The budget impact of OMPs in Sweden and France is likely to remain sustainable over time and a relatively small proportion of total pharmaceutical expenditure. This forecast could be affected by changes in the success rate for OMP approvals, average cost of OMPs, and the type of companies developing OMPs.

  6. Re-Emergence of Bluetongue Virus Serotype 8 in France, 2015.

    PubMed

    Sailleau, C; Bréard, E; Viarouge, C; Vitour, D; Romey, A; Garnier, A; Fablet, A; Lowenski, S; Gorna, K; Caignard, G; Pagneux, C; Zientara, S

    2017-06-01

    At the end of August 2015, a ram located in central France (department of Allier) showed clinical signs suggestive of BTV (Bluetongue virus) infection. However, none of the other animals located in the herd showed any signs of the Bluetongue disease. Laboratory analyses identified the virus as BTV serotype 8. The viro and sero prevalence intraherd were 2.4% and 8.6% in sheep and 18.3% and 42.9% in cattle, respectively. Phylogenetic studies showed that the sequences of this strain are closely related to another BTV-8 strain that has circulated in France in 2006-2008. The origin of the outbreak is unclear but it may be assumed that the BTV-8 has probably circulated at very low prevalence (possibly in livestock or wildlife) since its first emergence in 2007-2008. © 2015 Blackwell Verlag GmbH.

  7. Mechanism of the ML4.0 25th April 2016 Lacq (SW France) earthquake related to the gas extraction field

    NASA Astrophysics Data System (ADS)

    Aochi, Hideo; Delatre, Mickael; Burnol, André

    2017-04-01

    There were 11 earthquakes of magnitude larger than 3.8 in metropolitan France in 2016 according to the available catalogue EMSC. Among them, the ML4.0 25th April 2016 earthquake is suspected to be induced in gas exploitation field of Lacq, south-western France, close to the Pyreneans. The area is briefly covered by French national broad-band and acceleration networks and the data are available from ORFEUS/EIDA (European Integrated Data Achieves, http://www.orfeus-eu.org/data/eida/index.html ). In order to understand the mechanism of this earthquake and the state-of-art of the reservoir, it is essential to study the reliability of the focal depth and mechanism. We carry out a moment-tensor inversion using Genetic Algorithm. We select three broad-band stations at distance of about 50 km and applied a bandpass filter between 16 and 32 seconds. Green functions are calculated for the 1D layered structure. We fix the epicenter position determined by RéNaSS (Réseau National de Surveillance Sismique, http://www.renass.unistra.fr) and change the possible focal depths. The inversions show a good convergence to a solution of Mw3.8 indicating EW running normal faulting. This mechanism is consistent with the reservoir geometry of the gas field and may be interpreted as subsidence of the reservoir. However the obtained solution does not fit the nearest station, located a few hundred meters from the epicenter, probably due to lack of the precise epicenter position and/or local structure.

  8. [Utilization of methylphenidate(Ritalin) in France].

    PubMed

    Frances, C; Hoizey, G; Millart, H; Trenque, T

    2002-01-01

    Methylphenidate (Ritalin) is the only psychostimulant approved in France and indicated in attention deficit hyperactivity disorder in children over 6 years. It is under restricted prescription and distribution conditions. As such, it requires a hospital initiated prescription from either a neurology, psychiatry or pediatric specialist and it is covered by the "narcotics" schedule. The French Pharmacovigilance database spontaneous adverse drug reactions reporting, since it was approved in 1995, were analyzed. 21 adverse drug reactions were reported. In 16 cases, methylphenidate was suspected. They were generally non-serious, mild side effects and in most cases promptly resolved. These results do not suggest methylphenidate misuse in France or an overuse in between 1300 and 4000 treated children, to date. Until more information is available concerning the long-term effects of methylphenidate, and in order to limit misuse, inappropriate or overuse, the current prescription and dispensing regulation should be maintained in France, and could well be developed in other countries.

  9. Ab initio calculations of anharmonic vibrational spectroscopy for hydrogen fluoride (HF)n (n = 3, 4) and mixed hydrogen fluoride/water (HF)n(H2O)n (n = 1, 2, 4) clusters

    NASA Technical Reports Server (NTRS)

    Chaban, Galina M.; Gerber, R. Benny

    2002-01-01

    Anharmonic vibrational frequencies and intensities are computed for hydrogen fluoride clusters (HF)n, with n = 3, 4 and mixed clusters of hydrogen fluoride with water (HF)n(H2O)n where n = 1, 2. For the (HF)4(H2O)4 complex, the vibrational spectra are calculated at the harmonic level, and anharmonic effects are estimated. Potential energy surfaces for these systems are obtained at the MP2/TZP level of electronic structure theory. Vibrational states are calculated from the potential surface points using the correlation-corrected vibrational self-consistent field method. The method accounts for the anharmonicities and couplings between all vibrational modes and provides fairly accurate anharmonic vibrational spectra that can be directly compared with experimental results without a need for empirical scaling. For (HF)n, good agreement is found with experimental data. This agreement shows that the Moller-Plesset (MP2) potential surfaces for these systems are reasonably reliable. The accuracy is best for the stiff intramolecular modes, which indicates the validity of MP2 in describing coupling between intramolecular and intermolecular degrees of freedom. For (HF)n(H2O)n experimental results are unavailable. The computed intramolecular frequencies show a strong dependence on cluster size. Intensity features are predicted for future experiments.

  10. 77 FR 63262 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-16

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 39 [Docket No. FAA-2012-1087; Directorate Identifier 2009-SW-32-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France... France: Docket No. FAA-2012-1087; Directorate Identifier 2009-SW-32-AD. (a) Applicability This AD applies...

  11. Pd n Ag (4-n) and Pd n Pt (4-n) clusters on MgO (100): a density functional surface genetic algorithm investigation

    DOE PAGES

    Heard, Christopher J.; Heiles, Sven; Vajda, Stefan; ...

    2014-08-07

    We employed the novel surface mode of the Birmingham Cluster Genetic Algorithm (S-BCGA) for the global optimisation of noble metal tetramers upon an MgO(100) substrate at the GGA-DFT level of theory. The effect of element identity and alloying in surface-bound neutral subnanometre clusters is determined by energetic comparison between all compositions of Pd nAg (4-n) and Pd nPt (4-n). And while the binding strengths to the surface increase in the order Pt > Pd > Ag, the excess energy profiles suggest a preference for mixed clusters for both cases. The binding of CO is also modelled, showing that the adsorptionmore » site can be predicted solely by electrophilicity. Comparison to CO binding on a single metal atom shows a reversal of the 5s-d activation process for clusters, weakening the cluster surface interaction on CO adsorption. Charge localisation determines homotop, CO binding and surface site preferences. Furthermore, the electronic behaviour, which is intermediate between molecular and metallic particles allows for tunable features in the subnanometre size range.« less

  12. Diversity of Group I and II Clostridium botulinum Strains from France Including Recently Identified Subtypes.

    PubMed

    Mazuet, Christelle; Legeay, Christine; Sautereau, Jean; Ma, Laurence; Bouchier, Christiane; Bouvet, Philippe; Popoff, Michel R

    2016-06-13

    In France, human botulism is mainly food-borne intoxication, whereas infant botulism is rare. A total of 99 group I and II Clostridium botulinum strains including 59 type A (12 historical isolates [1947-1961], 43 from France [1986-2013], 3 from other countries, and 1 collection strain), 31 type B (3 historical, 23 recent isolates, 4 from other countries, and 1 collection strain), and 9 type E (5 historical, 3 isolates, and 1 collection strain) were investigated by botulinum locus gene sequencing and multilocus sequence typing analysis. Historical C. botulinum A strains mainly belonged to subtype A1 and sequence type (ST) 1, whereas recent strains exhibited a wide genetic diversity: subtype A1 in orfX or ha locus, A1(B), A1(F), A2, A2b2, A5(B2') A5(B3'), as well as the recently identified A7 and A8 subtypes, and were distributed into 25 STs. Clostridium botulinum A1(B) was the most frequent subtype from food-borne botulism and food. Group I C. botulinum type B in France were mainly subtype B2 (14 out of 20 historical and recent strains) and were divided into 19 STs. Food-borne botulism resulting from ham consumption during the recent period was due to group II C. botulinum B4. Type E botulism is rare in France, 5 historical and 1 recent strains were subtype E3. A subtype E12 was recently identified from an unusual ham contamination. Clostridium botulinum strains from human botulism in France showed a wide genetic diversity and seems to result not from a single evolutionary lineage but from multiple and independent genetic rearrangements. © The Author 2016. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

  13. Diversity of Group I and II Clostridium botulinum Strains from France Including Recently Identified Subtypes

    PubMed Central

    Mazuet, Christelle; Legeay, Christine; Sautereau, Jean; Ma, Laurence; Bouchier, Christiane; Bouvet, Philippe; Popoff, Michel R.

    2016-01-01

    In France, human botulism is mainly food-borne intoxication, whereas infant botulism is rare. A total of 99 group I and II Clostridium botulinum strains including 59 type A (12 historical isolates [1947–1961], 43 from France [1986–2013], 3 from other countries, and 1 collection strain), 31 type B (3 historical, 23 recent isolates, 4 from other countries, and 1 collection strain), and 9 type E (5 historical, 3 isolates, and 1 collection strain) were investigated by botulinum locus gene sequencing and multilocus sequence typing analysis. Historical C. botulinum A strains mainly belonged to subtype A1 and sequence type (ST) 1, whereas recent strains exhibited a wide genetic diversity: subtype A1 in orfX or ha locus, A1(B), A1(F), A2, A2b2, A5(B2′) A5(B3′), as well as the recently identified A7 and A8 subtypes, and were distributed into 25 STs. Clostridium botulinum A1(B) was the most frequent subtype from food-borne botulism and food. Group I C. botulinum type B in France were mainly subtype B2 (14 out of 20 historical and recent strains) and were divided into 19 STs. Food-borne botulism resulting from ham consumption during the recent period was due to group II C. botulinum B4. Type E botulism is rare in France, 5 historical and 1 recent strains were subtype E3. A subtype E12 was recently identified from an unusual ham contamination. Clostridium botulinum strains from human botulism in France showed a wide genetic diversity and seems to result not from a single evolutionary lineage but from multiple and independent genetic rearrangements. PMID:27189984

  14. MICROWAVE SPECTROSCOPY OF THE CALCIUM 4snf→4s(n+1)d, 4sng, 4snh, 4sni, AND 4snk TRANSITIONS

    NASA Astrophysics Data System (ADS)

    Nunkaew, Jirakan; Gallagher, Tom

    2015-06-01

    We use a delayed field ionization technique to observe the microwave transitions of calcium Rydberg states, from the 4snf states to the 4s(n+1)d, 4sng, 4snh, 4sni, and 4snk states for 18≤ n≤23. We analyze the observed intervals between the ℓ and (ℓ+1), ℓ≥5, states of the same n to determine the Ca^+ 4s dipole and quadrupole polarizabilities. We show that the adiabatic core polarization model is not adequate to extract the Ca^+ 4s dipole and quadrupole polarizabilities and a non adiabatic treatment is required. We use the non adiabatic core polarization model to determine the ionic dipole and quadrupole polarizabilities to be α_d=76.9(3);a_0^3 and α_q=206(9);a_0^5, respectively.

  15. Photochromism of 7-(N,N-diethylamino)-4'-hydroxyflavylium in a water-ionic liquid biphasic system.

    PubMed

    Pina, Fernando; Parola, A Jorge; Melo, Maria João; Laia, César A T; Afonso, Carlos A M

    2007-04-28

    Photochromism of trans-4-(N,N-diethylamino)-2,4'-dihydroxychalcone, with formation of the photoproduct 7-(N,N-diethylamino)-4'-hydroxyflavylium, is promoted in the ionic liquid phase of a water/[bmim][PF6] biphasic system.

  16. Ranibizumab for choroidal neovascularization secondary to pseudoxanthoma elasticum: 4-year results from the PIXEL study in France.

    PubMed

    Mimoun, Gérard; Ebran, Jean-Marc; Grenet, Typhaine; Donati, Alain; Cohen, Salomon-Yves; Ponthieux, Anne

    2017-08-01

    To evaluate the long-term effectiveness and safety of ranibizumab 0.5 mg in patients with choroidal neovascularization (CNV) secondary to pseudoxanthoma elasticum (PXE) in a real-world setting. A descriptive, observational, multicenter study in a retrospective and prospective cohort was conducted in France that included patients who had received at least one injection of ranibizumab 0.5 mg during the period October 2011 to October 2014, for CNV secondary to PXE. Eligible patients were identified by review of medical records or during routine consultations. The main objectives were to describe patient characteristics, assess changes in best-corrected visual acuity [VA, Early Treatment Diabetic Retinopathy Study (ETDRS) letters] over time, the number and reasons for ranibizumab treatment and overall safety. Of the 72 enrolled patients (98 eyes) from 23 centers, 39 (54.2%) were male and mean [±standard deviation (SD)] age was 59.6 (±8.3) years. The mean VA was 64.6 letters at the first ranibizumab injection, which was maintained at the 1-year follow-up (64.7 letters). Thereafter, the mean VA was stable until the 4-year follow-up. At 4 years, the proportion of eyes with VA gain of ≥15 letters was 3/19 (15.8%) and stable VA (change between -15 and +15 letters) was 10/19 (52.6%). Mean (±SD) annual number of ranibizumab injections was 4.1 (±4.0), lower in the second versus first year. The most common reason for ranibizumab treatment was progression of neovascular activity (42.9%). No deaths or new safety findings were reported. In patients with CNV secondary to PXE, ranibizumab 0.5 mg resulted in stable VA over 4 years with a limited number of injections. Safety findings were consistent with the established safety profile of ranibizumab.

  17. More N =4 superconformal bootstrap

    NASA Astrophysics Data System (ADS)

    Beem, Christopher; Rastelli, Leonardo; van Rees, Balt C.

    2017-08-01

    In this long overdue second installment, we continue to develop the conformal bootstrap program for N =4 superconformal field theories (SCFTs) in four dimensions via an analysis of the correlation function of four stress-tensor supermultiplets. We review analytic results for this correlator and make contact with the SCFT/chiral algebra correspondence of Beem et al. [Commun. Math. Phys. 336, 1359 (2015), 10.1007/s00220-014-2272-x]. We demonstrate that the constraints of unitarity and crossing symmetry require the central charge c to be greater than or equal to 3 /4 in any interacting N =4 SCFT. We apply numerical bootstrap methods to derive upper bounds on scaling dimensions and operator product expansion coefficients for several low-lying, unprotected operators as a function of the central charge. We interpret our bounds in the context of N =4 super Yang-Mills theories, formulating a series of conjectures regarding the embedding of the conformal manifold—parametrized by the complexified gauge coupling—into the space of scaling dimensions and operator product expansion coefficients. Our conjectures assign a distinguished role to points on the conformal manifold that are self-dual under a subgroup of the S -duality group. This paper contains a more detailed exposition of a number of results previously reported in Beem et al. [Phys. Rev. Lett. 111, 071601 (2013), 10.1103/PhysRevLett.111.071601] in addition to new results.

  18. Evaluating the Effectiveness of France's Indoor Smoke-Free Law 1 Year and 5 Years after Implementation: Findings from the ITC France Survey.

    PubMed

    Fong, Geoffrey T; Craig, Lorraine V; Guignard, Romain; Nagelhout, Gera E; Tait, Megan K; Driezen, Pete; Kennedy, Ryan David; Boudreau, Christian; Wilquin, Jean-Louis; Deutsch, Antoine; Beck, François

    2013-01-01

    France implemented a comprehensive smoke-free law in two phases: Phase 1 (February 2007) banned smoking in workplaces, shopping centres, airports, train stations, hospitals, and schools; Phase 2 (January 2008) banned smoking in hospitality venues (bars, restaurants, hotels, casinos, nightclubs). This paper evaluates France's smoke-free law based on the International Tobacco Control Policy Evaluation Project in France (the ITC France Project), which conducted a cohort survey of approximately 1,500 smokers and 500 non-smokers before the implementation of the laws (Wave 1) and two waves after the implementation (Waves 2 and 3). Results show that the smoke-free law led to a very significant and near-total elimination of observed smoking in key venues such as bars (from 94-97% to 4%) and restaurants (from 60-71% to 2-3%) at Wave 2, which was sustained four years later (6-8% in bars; 1-2% in restaurants). The reduction in self-reported smoking by smoking respondents was nearly identical to the effects shown in observed smoking. Observed smoking in workplaces declined significantly after the law (from 41-48% to 18-20%), which continued to decline at Wave 3 (to 14-15%). Support for the smoke-free laws increased significantly after their implementation and continued to increase at Wave 3 (p<.001 among smokers for bars and restaurants; p<.001 among smokers and p = .003 for non-smokers for workplaces). The findings demonstrate that smoke-free policies that are implemented in ways consistent with the Guidelines for Article 8 of the WHO Framework Convention on Tobacco Control (WHO FCTC) lead to substantial and sustained reductions in indoor smoking while also leading to high levels of support by the public. Moreover, contrary to arguments by opponents of smoke-free laws, smoking in the home did not increase after the law was implemented and prevalence of smoke-free homes among smokers increased from 23.2% before the law to 37.2% 5 years after the law.

  19. [Factors associated with mortality in Legionnaires' disease, France, 2002-2004].

    PubMed

    Poupard, M; Campèse, C; Bernillon, P; Che, D

    2007-06-01

    Risk factors for Legionnaires' disease are well known (older age, smoking, or immunosuppression), however, the factors associated with mortality are less documented. A retrospective analysis based on cases notified between 2002 and 2004 was conducted in France to identify these factors. Cases were identified through mandatory notifications sent to the Institut de veille sanitaire, France. Factors associated with mortality were identified using a logistic regression analysis. Three thousand two hundred sixty-seven cases of Legionnaire's disease were notified during the study period and the evolution was documented for 85% of the cases (2.791). Three hundred seventy-seven deaths (13.5%) were notified. 72.5% of the patients were men and the median age was 61. The multivariate analysis applied to patients under 60 years revealed that cancer or hemopathy (OR=6.4 CI95% 3.6-11.2), underlying renal disease (OR=3.2 CI95% 1.0-9.9), or alcohol abuse (OR=2.2 CI95% 1.1-4.4) were associated with mortality. For older patients (>60 years) factors linked to mortality were: cancer/hemopathy (OR=1.8 CI95% 1.2-2.6), underlying renal disease (OR=3 CI95% 1.4-6.4), underlying cardiac disease (OR=2.4 CI95% 1.4-4), alcohol abuse (OR=2.4 CI95% 1.2-5.2), immunosuppression (OR=1.7 CI95% 1.1-2.6), nosocomial acquisition of the disease (OR=2.0 CI95% 1.3-3), or infection acquired in nursing home residents (OR=2.4 IC 95% 1.6-3.6). These preliminary results further describe Legionnaires' disease and its mortality. However, they should be confirmed by carefully conducted prospective analysis. The description of LD patients at high risk of death will contribute to better prevention measures.

  20. International Reports on Literacy Research: France and Argentina

    ERIC Educational Resources Information Center

    Malloy, Jacquelynn A., Comp.; Botzakis, Stergios, Comp.

    2006-01-01

    This is a compilation of two separate reports on international literacy research from France and Argentina. In the reports from France, research correspondent Jacques Fijalkow detailed three research projects that included the following: (1) A description of adult literacy skills; (2) An investigation of how study-abroad students were integrated…

  1. The Challenges Facing Catholic Education in France Today

    ERIC Educational Resources Information Center

    Moog, François

    2016-01-01

    The effects of secularisation on society demand a rethinking of the identity and mission of Catholic schools in France. In 2013, the French bishops published a new directory which offers new approaches, described here, based on the three challenges facing Catholic education in France: linking social responsibility and evangelisation, setting up…

  2. 47 CFR 3.46 - Use of gold francs.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 1 2014-10-01 2014-10-01 false Use of gold francs. 3.46 Section 3.46... AUTHORITIES IN MARITIME AND MARITIME MOBILE-SATELLITE RADIO SERVICES Settlement Operations § 3.46 Use of gold francs. An accounting authority must accept accounts presented to it from foreign administrations in gold...

  3. 47 CFR 3.46 - Use of gold francs.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 1 2013-10-01 2013-10-01 false Use of gold francs. 3.46 Section 3.46... AUTHORITIES IN MARITIME AND MARITIME MOBILE-SATELLITE RADIO SERVICES Settlement Operations § 3.46 Use of gold francs. An accounting authority must accept accounts presented to it from foreign administrations in gold...

  4. 47 CFR 3.46 - Use of gold francs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Use of gold francs. 3.46 Section 3.46... AUTHORITIES IN MARITIME AND MARITIME MOBILE-SATELLITE RADIO SERVICES Settlement Operations § 3.46 Use of gold francs. An accounting authority must accept accounts presented to it from foreign administrations in gold...

  5. 47 CFR 3.46 - Use of gold francs.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 1 2011-10-01 2011-10-01 false Use of gold francs. 3.46 Section 3.46... AUTHORITIES IN MARITIME AND MARITIME MOBILE-SATELLITE RADIO SERVICES Settlement Operations § 3.46 Use of gold francs. An accounting authority must accept accounts presented to it from foreign administrations in gold...

  6. 47 CFR 3.46 - Use of gold francs.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 1 2012-10-01 2012-10-01 false Use of gold francs. 3.46 Section 3.46... AUTHORITIES IN MARITIME AND MARITIME MOBILE-SATELLITE RADIO SERVICES Settlement Operations § 3.46 Use of gold francs. An accounting authority must accept accounts presented to it from foreign administrations in gold...

  7. Socio-economic characteristics, living conditions and diet quality are associated with food insecurity in France.

    PubMed

    Bocquier, Aurélie; Vieux, Florent; Lioret, Sandrine; Dubuisson, Carine; Caillavet, France; Darmon, Nicole

    2015-11-01

    To assess the prevalence of household food insecurity (FI) in France and to describe its associations with socio-economic factors, health behaviours, diet quality and cost (estimated using mean food prices). Cross-sectional nationally representative survey. FI was assessed using an adapted version of the US Department of Agriculture's Food Insufficiency Indicator; dietary intake was assessed using a 7 d open-ended food record; and individual demographic, socio-economic and behavioural variables were assessed using self-administered questionnaires and interviews. Individuals experiencing FI were compared with food-secure individuals, the latter being divided into four categories according to quartiles of their income per consumption unit (FS1 to FS4). Differences among categories were analysed using χ² tests, ANOVA and tests for trend. Individual and National Dietary Survey (INCA2), 2006-2007. Adults aged 18-79 years (n 2624). Individuals experiencing FI represented 12·2% of the population. They were on average younger, more frequently women and single parents with children compared with those in the other four categories. Their mean income per consumption unit was higher than that in the FS1 category, but they reported poorer material and housing conditions. The prevalence of smoking and the mean daily time spent watching television were also higher in the FI category. No significant difference among categories was found for energy intake, but mean intakes of fruits, vegetables and fish were lower, and diet quality was slightly but significantly poorer in the FI category. Daily diet cost was also lower in the FI category. France is not spared by FI. FI should be routinely monitored at the national level and research should be promoted to identify effective strategies to reduce nutrition inequalities in France.

  8. Visible Light-Driven Photocatalytic Performance of N-Doped ZnO/g-C3N4 Nanocomposites.

    PubMed

    Kong, Ji-Zhou; Zhai, Hai-Fa; Zhang, Wei; Wang, Shan-Shan; Zhao, Xi-Rui; Li, Min; Li, Hui; Li, Ai-Dong; Wu, Di

    2017-09-06

    N-doped ZnO/g-C 3 N 4 composites have been successfully prepared via a facile and cost-effective sol-gel method. The nanocomposites were systematically characterized by XRD, FE-SEM, HRTEM, FT-IR, XPS, and UV-vis DRS. The results indicated that compared with the pure N-doped ZnO, the absorption edge of binary N-doped ZnO/g-C 3 N 4 shifted to a lower energy with increasing the visible-light absorption and improving the charge separation efficiency, which would enhance its photocatalytic activity. Compared with the pure g-C 3 N 4 , ZnO, N-doped ZnO and the composite ZnO/g-C 3 N 4 , the as-prepared N-doped ZnO/g-C 3 N 4 exhibits a greatly enhanced photocatalytic degradation of methylene blue and phenol under visible-light irradiation. Meanwhile, N-doped ZnO/g-C 3 N 4 possesses a high stability. Finally, a proposed mechanism for N-doped ZnO/g-C 3 N 4 is also discussed. The improved photocatalysis can be attributed to the synergistic effect between N-doped ZnO and g-C 3 N 4 , including the energy band structure and enhanced charge separation efficiency.

  9. Metabolism of 4-N-Hydroxy-Cytidine in Escherichia coli

    PubMed Central

    Trimble, R. B.; Maley, Frank

    1971-01-01

    4-N-hydroxy-cytidine was found to substitute for uridine as a pyrimidine supplement for the growth of Escherichia coli Bu−. Measurement of the incorporation of 4-N-hydroxy-cytidine-2-14C into ribonucleic acid and deoxyribonucleic acid revealed that this compound was converted to cytidine or uridine before utilization. Two pathways for metabolism were considered: (i) the reduction of 4-N-hydroxy-cytidine to cytidine followed by deamination, (ii) the direct hydrolysis of hydroxylamine from 4-N-hydroxy-cytidine to yield uridine. A threefold increase in cytidine (deoxycytidine) deaminase (EC 3.5.4.5) activity, when the cells were grown on 4-N-hydroxy-cytidine, suggested the involvement of this enzyme. More direct proof was obtained by purifying the deaminase 185-fold and finding that it released hydroxylamine from 4-N-hydroxy-cytidine at one-fiftieth the rate at which ammonia was removed from cytidine. This result is consistent with the slower rate of growth of the Bu− cells on 4-N-hydroxy-cytidine than cytidine and suggests that the second pathway is the major route for utilization of this compound. PMID:4941553

  10. Echinococcus ortleppi Infections in Humans and Cattle, France

    PubMed Central

    Umhang, Gérald; Arbez-Gindre, Francine; Mantion, Georges; Delabrousse, Eric; Millon, Laurence; Boué, Franck

    2014-01-01

    In 2011 and 2012, liver infections caused by Echinococcus ortleppi tapeworms were diagnosed in 2 humans in France. In 2012, a nationwide slaughterhouse survey identified 7 E. ortleppi infections in cattle. The foci for these infections were spatially distinct. The prevalence of E. ortleppi infections in France may be underestimated. PMID:25417697

  11. In Wake of Riots, France Refashions Priority Zones

    ERIC Educational Resources Information Center

    Hendrie, Caroline

    2006-01-01

    This article deals with an initiative embarked upon by the government of France one year after widespread youth violence broke out in many disadvantaged communities in France. The initiative is aimed at adapting its 25-year-old "priority education" program to a landscape that has dramatically changed. The initiative is the centerpiece of…

  12. CH4 and N2O emissions embodied in international trade of meat

    NASA Astrophysics Data System (ADS)

    Caro, Dario; LoPresti, Anna; Davis, Steven J.; Bastianoni, Simone; Caldeira, Ken

    2014-11-01

    Although previous studies have quantified carbon dioxide emissions embodied in products traded internationally, there has been limited attention to other greenhouse gases such as methane (CH4) and nitrous oxide (N2O). Following IPCC guidelines, we estimate non-CO2 emissions from beef, pork and chicken produced in 237 countries over the period 1990-2010, and assign these emissions to the country where the meat is ultimately consumed. We find that, between 1990 and 2010, an average of 32.8 Mt CO2-eq emissions (using 100 year global warming potentials) are embodied in beef, pork and chicken traded internationally. Further, over the 20 year period, the quantity of CO2-eq emissions embodied in traded meat increased by 19%. The largest trade flows of emissions embodied in meat were from Brazil and Argentina to Russia (2.8 and 1.4 Mt of CO2-eq, respectively). Trade flows within the European region are also substantial: beef and pork exported from France embodied 3.3 Mt and 0.4 Mt of CO2-eq, respectively. Emissions factor of meat production (i.e. CO2-eq emissions per kg of meat) produced depend on ambient temperature, development level, livestock category (e.g. cattle, pork, and chicken) and livestock management practices. Thus, trade may result in an overall increase of GHG emissions when meat-consuming countries import meat from countries with a greater emissions intensity of meat production rather than producing the meat domestically. Comparing the emissions intensity of meat production of trading partners, we assess trade flows according to whether they tend to reduce or increase global emissions from meat production.

  13. Estimating the budget impact of orphan drugs in Sweden and France 2013–2020

    PubMed Central

    2014-01-01

    Background The growth in expenditure on orphan medicinal products (OMP) across Europe has been identified as a concern. Estimates of future expenditure in Europe have suggested that OMPs could account for a significant proportion of total pharmaceutical expenditure in some countries, but few of these forecasts have been well validated. This analysis aims to establish a robust forecast of the future budget impact of OMPs on the healthcare systems in Sweden and France. Methods A dynamic forecasting model was created to estimate the budget impact of OMPs in Sweden and France between 2013 and 2020. The model used historical data on OMP designation and approval rates to predict the number of new OMPs coming to the market. Average OMP sales were estimated for each year post-launch by regression analysis of historical sales data. Total forecast sales were compared with expected sales of all pharmaceuticals in each country to quantify the relative budget impact. Results The model predicts that by 2020, 152 OMPs will have marketing authorization in Europe. The base case OMP budget impacts are forecast to grow from 2.7% in Sweden and 3.2% in France of total drug expenditure in 2013 to 4.1% in Sweden and 4.9% in France by 2020. The principal driver of expenditure growth is the number of new OMPs obtaining OMP designation. This is tempered by the slowing success rate for new approvals and the loss of intellectual property protection on existing orphan medicines. Given the forward-looking nature of the analysis, uncertainty exists around model parameters and sensitivity analysis found peak year budget impact varying between 2% and 11%. Conclusion The budget impact of OMPs in Sweden and France is likely to remain sustainable over time and a relatively small proportion of total pharmaceutical expenditure. This forecast could be affected by changes in the success rate for OMP approvals, average cost of OMPs, and the type of companies developing OMPs. PMID:24524281

  14. [History of clinical pharmacology in France: adaptation, evaluation, defense and illustration of drug in France 1978-1981].

    PubMed

    Montastruc, Paul

    2014-01-01

    This text illustrates some unknown aspects of the history and beginnings of clinical pharmacology in France in the late 1970s and early 1980s From the current situation, development and objectives of clinical pharmacology are recalled as well as obstacles necessary to overcome to change the paradigm in the field of drug evaluation and appropriate use in France. The text recalls this important moment where French medicine and medical pharmacology entered the modern era. © 2014 Société Française de Pharmacologie et de Thérapeutique.

  15. N =4 supersymmetric mechanics on curved spaces

    NASA Astrophysics Data System (ADS)

    Kozyrev, Nikolay; Krivonos, Sergey; Lechtenfeld, Olaf; Nersessian, Armen; Sutulin, Anton

    2018-04-01

    We present N =4 supersymmetric mechanics on n -dimensional Riemannian manifolds constructed within the Hamiltonian approach. The structure functions entering the supercharges and the Hamiltonian obey modified covariant constancy equations as well as modified Witten-Dijkgraaf-Verlinde-Verlinde equations specified by the presence of the manifold's curvature tensor. Solutions of original Witten-Dijkgraaf-Verlinde-Verlinde equations and related prepotentials defining N =4 superconformal mechanics in flat space can be lifted to s o (n )-invariant Riemannian manifolds. For the Hamiltonian this lift generates an additional potential term which, on spheres and (two-sheeted) hyperboloids, becomes a Higgs-oscillator potential. In particular, the sum of n copies of one-dimensional conformal mechanics results in a specific superintegrable deformation of the Higgs oscillator.

  16. X-ray diffraction analysis of 4- and 4'-substituted C n H2 n + 1O-C6H3(OH)-CH=N-C6H4-C m H2 m + 1 ( n/ m = 2/1 and 3/4) salicylideneanilines

    NASA Astrophysics Data System (ADS)

    Kuz'mina, L. G.; Navasardyan, M. A.; Mikhailov, A. A.

    2017-11-01

    X-ray diffraction study of two crystalline modifications of C2H5O-C6H3(OH)-CH=N-C6H4-CH3 ( 1a, sp. gr. P21/ n, and 1b, sp. gr. C2/c) and C3H7O-C6H3(OH)-CH=N-C6H4-C4H9 ( 2, sp. gr. P212121) has been performed. The 1a crystal structure contains two independent molecules. The molecules are conformationally nonrigid with respect to the mutual rotation of benzene rings; the dihedral angles between their planes are 29.19° and 26.00° in the independent molecules of 1a, 18.72° in the molecule of 1b, and 50.35° in the molecule of 2. The crystal packing of the compounds is discussed.

  17. Anhydrous versus hydrated N4-substituted 1H-pyrazolo[3,4-d]pyrimidine-4,6-diamines: hydrogen bonding in two and three dimensions.

    PubMed

    Trilleras, Jorge; Quiroga, Jairo; Cobo, Justo; Marchal, Antonio; Nogueras, Manuel; Low, John N; Glidewell, Christopher

    2008-10-01

    Ten new N(4)-substituted 1H-pyrazolo[3,4-d]pyrimidine-4,6-diamines have been synthesized and the structures of nine of them are reported here, falling into two clear groups, those which are stoichiometric hydrates and those which crystallize in solvent-free forms. In each of N(4)-methyl-N(4)-phenyl-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine, C(12)H(12)N(6) (I), N(4)-cyclohexyl-N(4)-methyl-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine, C(12)H(18)N(6) (II), and N(4)-(3-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine, C(11)H(9)ClN(6) (III), the molecules are linked into hydrogen-bonded sheets. The molecules of 2-{4-(6-amino-1H-pyrazolo[3,4-d]pyrimidin-4-yl)piperazin-1-yl}ethanol, C(11)H(17)N(7)O (IV), are linked into a three-dimensional framework, while the structure of N(4)-methyl-N(4)-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine monohydrate, C(13)H(14)N(6) x H(2)O (V), is only two-dimensional despite the presence of five independent hydrogen bonds. The stoichiometric hemihydrates N(4)-ethyl-N(4)-phenyl-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine hemihydrate, C(13)H(14)N(6) x 0.5 H(2)O (VI) and N(4)-(4-methoxyphenyl)-N(4)-methyl-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine hemihydrate, C(13)H(14)N(6)O x 0.5 H(2)O (VII), exhibit remarkably similar sheet structures, despite different space groups and Z' values, Z' = 0.5 in C2/c for (VI) and Z' = 1 in P1 for (VII). N(4)-4-Benzyl-N(4)-phenyl-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine monohydrate, C(18)H(16)N(6) x H(2)O (VIII), crystallizes with Z' = 2 in P2(1)/n, and the four independent molecular components are linked into sheets by a total of 11 intermolecular hydrogen bonds. The sheet structure in {4-(pyrrolidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine-6-amine} ethanol hemisolvate hemihydrate, C(9)H(12)N(6).0.5C(2)H(6)O x 0.5 H(2)O (IX), is built from the pyrimidine and water components only; it contains eight independent hydrogen bonds, and it very closely mimics the sheets in (VI) and (VII); the ethanol molecules are

  18. Crystal growth of triphenylphosphine oxide 4-nitrophenol (TP4N) for nonlinear optical (NLO) applications

    NASA Astrophysics Data System (ADS)

    Pandian, Muthu Senthil; Karuppasamy, P.; Kamalesh, T.; Ramasamy, P.; Verma, Sunil

    2018-04-01

    The optically good quality organic single crystals of triphenylphosphine oxide 4-nitrophenol (TP4N) were successfully grown by slow evaporation solution technique (SEST) using methanol as solvent. The lattice parameters of the grown crystal were confirmed by single crystal X-ray diffraction analysis. The optical transmittance, cut-off wavelength and band gap of the TP4N crystal were obtained by UV-Vis NIR spectrum analysis. The photoluminescence studies were carried out to find out the luminesce properties of TP4N single crystal. The photoconductivity studies reveal that the TP4N crystal has negative photoconductive nature. The third order nonlinear susceptibility (χ(3)) of TP4N crystal was evaluated using the Z-scan technique at 640 nm.

  19. The e-Bug project in France.

    PubMed

    Touboul, Pia; Dunais, Brigitte; Urcun, Jeanne-Marie; Michard, Jean-Louis; Loarer, Christian; Azanowsky, Jean-Michel; Vincent, Isabelle; Jestin, Christine; Housseau, Bruno; de Warren, Anne; Dellamonica, Pierre

    2011-06-01

    The high rates of antibiotic prescriptions and antimicrobial resistance in France motivated its participation in the European e-Bug school project concerning microbes, and infection transmission, prevention and treatment. The prospect of raising awareness among children, helping them to adopt suitable attitudes and behaviour towards infection transmission and treatment starting from childhood, generated enthusiastic support from relevant national educational and health institutions throughout the Project. France was actively involved in every stage: background research showed that the subject matter was best suited to the national science curricula of the fourth and fifth forms in junior schools, and the sixth and ninth forms in senior schools; a focus group study with junior and senior teachers elicited teachers' needs concerning teaching resources; and a qualitative and quantitative evaluation, after translation and pack review, enabled further adaptation of the packs. This evaluation showed an overall enthusiastic reception by teachers and their students in France, and reassured teachers on the ease of use of the Project's resources and students' progress. The e-Bug Project was launched through a national institutional implementation plan in September 2009 and orders for e-Bug tools increased rapidly. By the end of October, 57% of all senior science teachers and 16% of all junior school teachers had ordered the pack. France is one of the most frequent users of the e-Bug web site. The collaboration with both educational and health partners was particularly helpful to implementing the Project, and this was confirmed by the favourable reception and participation of teachers and students in the field.

  20. Comparison of rehospitalization rates in France and the United States.

    PubMed

    Gusmano, Michael; Rodwin, Victor; Weisz, Daniel; Cottenet, Jonathan; Quantin, Catherine

    2015-01-01

    To compare rates of 30-day all-cause rehospitalization in France and the US among patients aged 65 years and older and explain any difference between the countries. To calculate rehospitalization rates in France, we use an individual identifying variable in the national hospital administrative dataset to track unique individuals aged 65 years or more hospitalized in France in 2010. To calculate the proportion of rehospitalized patients (65+) who received outpatient visits between the time of initial discharge and rehospitalization, we linked the hospital database with a database that includes all medical and surgical admissions. We used step by step regression models to predict rehospitalization. Rates of rehospitalization in France (14.7%) are lower than among Medicare beneficiaries in the US (20%). We find that age, sex, patient morbidity and the ownership status of the hospital are all correlated with rehospitalization in France. Lower rates of rehospitalization in France appear to be due to a combination of better access to primary care, better health among the older French population, longer lengths of stay in French hospitals and the fact that French nursing homes do not face the same financial incentive to rehospitalize residents. © The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

  1. Superconductivity at 33-37 K in A L n2Fe4As4O2 (A =Kand Cs;L n =lanthanides)

    NASA Astrophysics Data System (ADS)

    Wu, Si-Qi; Wang, Zhi-Cheng; He, Chao-Yang; Tang, Zhang-Tu; Liu, Yi; Cao, Guang-Han

    2017-09-01

    We have synthesized ten iron oxyarsenides, K L n2Fe4As4O2 (L n =Gd,Tb,Dy, and Ho) and Cs L n2Fe4As4O2 (L n =Nd,Sm,Gd,Tb,Dy, and Ho) , with the aid of the lattice-match approach. The resultant compounds possess hole-doped conducting double FeAs layers [AFe4As4] 2 - that are separated by the insulating [Ln2O2] 2 + slabs. Measurements of electrical resistivity and dc magnetic susceptibility demonstrate bulk superconductivity at Tc=33 -37 K. We find that Tc correlates with the axial ratio c /a for all 12442-type superconductors discovered. Also, Tc tends to increase with the lattice mismatch, implying that lattice instability plays a role in the enhancement of superconductivity.

  2. [Air quality surveillance in France].

    PubMed

    Téton, S; Robin, D; Genève, C

    2009-10-01

    As air quality has a direct impact on human health, its monitoring is imperative. In France, this task was entrusted by the government (Air Law of 1996) to organisations with territorial responsibility: the Registered Associations for the Surveillance of Air Quality. The type and level of pollution evolve: from industrial and sulphur pollution in the seventies, to urban and photochemical pollution today and to nanoparticles, pesticides and pollutants in buildings tomorrow. The tools, the skills and the roles of the different people involved in air quality control follow these sometimes rapid transitions in connection with an increasingly precise understanding of the relationship between health and the environment and of the considerable research on the subject. This article describes the mechanisms of air quality monitoring in France.

  3. Characterization of solvated electrons in hydrogen cyanide clusters: (HCN)n- (n=3, 4)

    NASA Astrophysics Data System (ADS)

    Wu, Di; Li, Ying; Li, Zhuo; Chen, Wei; Li, Zhi-Ru; Sun, Chia-Chung

    2006-02-01

    Theoretical studies of the solvated electrons (HCN)n- (n =3, 4) reveal a variety of electron trapping possibilities in the (HCN)n (n =3, 4) clusters. Two isomers for (HCN)3- and four isomers for (HCN)4- are obtained at the MP2/aug -cc-pVDZ+dBF (diffusive bond functions) level of theory. In view of vertical electron detachment energies (VDEs) at the CCSD(T) level, the excess electron always "prefers" locating in the center of the system, i.e., the isomer with higher coordination number shows larger VDE value. However, the most stable isomers of the solvated electron state (HCN)3- and (HCN)4- are found to be the linear C∞ν and D∞h structures, respectively, but not the fullyl symmetric structures which have the largest VDE values.

  4. Structure and magnetization of Co4N thin film

    NASA Astrophysics Data System (ADS)

    Pandey, Nidhi; Gupta, Mukul; Gupta, Rachana; Rajput, Parasmani; Stahn, Jochen

    2018-02-01

    In this work, we studied the local structure and the magnetization of Co4N thin films deposited by a reactive dc magnetron sputtering process. The interstitial incorporation of N atoms in a fcc Co lattice is expected to expand the structure. This expansion yields interesting magnetic properties e.g. a larger magnetic moment (than Co) and a very high value of spin polarization ratio in Co4N . By optimizing the growth conditions, we prepared Co4N film having lattice parameter close to its theoretically predicted value. The N concentration was measured using secondary ion mass spectroscopy. Detailed magnetization measurements using bulk magnetization method and polarized neutron reflectivity confirm that the magnetic moment of Co in Co4N is higher than that of Co.

  5. 40 CFR 721.10164 - Benzenecarboximidamide, N-hydroxy-4-nitro-.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Benzenecarboximidamide, N-hydroxy-4... Specific Chemical Substances § 721.10164 Benzenecarboximidamide, N-hydroxy-4-nitro-. (a) Chemical substance... benzenecarboximidamide, N-hydroxy-4-nitro- (PMN P-08-36; CAS No. 1613-86-1) is subject to reporting under this section...

  6. 40 CFR 721.10164 - Benzenecarboximidamide, N-hydroxy-4-nitro-.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 31 2011-07-01 2011-07-01 false Benzenecarboximidamide, N-hydroxy-4... Specific Chemical Substances § 721.10164 Benzenecarboximidamide, N-hydroxy-4-nitro-. (a) Chemical substance... benzenecarboximidamide, N-hydroxy-4-nitro- (PMN P-08-36; CAS No. 1613-86-1) is subject to reporting under this section...

  7. Three years of semicontinuous greenhouse gas measurements at the Puy de Dôme station (central France)

    NASA Astrophysics Data System (ADS)

    Lopez, M.; Schmidt, M.; Ramonet, M.; Bonne, J.-L.; Colomb, A.; Kazan, V.; Laj, P.; Pichon, J.-M.

    2015-09-01

    Three years of greenhouse gas measurements, obtained using a gas chromatograph (GC) system located at the Puy de Dôme station at 1465 m a.s.l. in central France, are presented. The GC system was installed in 2010 at Puy de Dôme and was designed for automatic and accurate semicontinuous measurements of atmospheric carbon dioxide, methane, nitrous oxide and sulfur hexafluoride mole fractions. We present in detail the instrumental setup and the calibration strategy, which together allow the GC to reach repeatabilities of 0.1 μmol mol-1, 1.2 nmol mol-1, 0.3 nmol mol-1 and 0.06 pmol mol-1 for CO2, CH4, N2O and SF6, respectively. The analysis of the 3-year atmospheric time series revealed how the planetary boundary layer height drives the mole fractions observed at a mountain site such as Puy de Dôme where air masses alternate between the planetary boundary layer and the free troposphere. Accurate long-lived greenhouse gas measurements collocated with 222Rn measurements as an atmospheric tracer allowed us to determine the CO2, CH4 and N2O emissions in the catchment area of the station. The derived CO2 surface flux revealed a clear seasonal cycle, with net uptake by plant assimilation in the spring and net emission caused by the biosphere and burning of fossil fuel during the remainder of the year. We calculated a mean annual CO2 flux of 1310 ± 680 t CO2 km-2. The derived CH4 and N2O emissions in the station catchment area were 7.0 ± 4.0 t CH4 km-2 yr-1 and 1.8 ± 1.0 t N2O km-2 yr-1, respectively. Our derived annual CH4 flux is in agreement with the national French inventory, whereas our derived N2O flux is 5 times larger than the same inventory.

  8. Fire occurrence prediction in the Mediterranean: Application to Southern France

    NASA Astrophysics Data System (ADS)

    Papakosta, Panagiota; Öster, Jan; Scherb, Anke; Straub, Daniel

    2013-04-01

    the German and French Weather Services (Deutscher Wetterdienst and Météo-France). Historical fire events are taken from Prométhée database. Time series 2000-2010 are used as learning data and data from 2011 is used as the validation data. The resulting model can support real-time fire risk estimation for improved allocation of firefighting resources and planning of other mitigation actions. [1] Keeley, J.E.; Bond, W.J.; Bradstock, R.A.; Pausas, J.G.; Rundel, P.W. (2012): Fire in Mediterranean ecosystems: ecology, evolution and management. Cambridge University Press, New York, USA, pp.515 [2] Lawson, B.D.; Armitage, O.B. (2008): Weather Guide for the Canadian Forest Fire Danger Rating System. Natural Resources Canada, Canadian Forest Service, Northern Forestry Centre, Edmonton, Alberta, Canada. [3] Van Wagner, C.E.; Pickett, T.L. (1985): Equations and FORTRAN Program for the Canadian Forest Fire Weather Index System. Forestry Technical Report 33. Canadian Forestry Service, Government of Canada, Ottawa, Ontario, Canada [4] Syphard, A.D.; Radeloff, V.C.; Keuler, N.S.; Taylor, R.S.; Hawbaker, T.J.; Stewart, S.I.; Clayton, M.K. (2008): Predicting spatial patterns of fire on a southern California landscape. International Journal of Wildland Fire, 17, pp.602-613 [5] Papakosta, P.; Klein, F.; König, S.; Straub, D. (2012): Linking spatio-temporal data to the Fire Weather Index to estimate the probability of wildfire in the Mediterranean. Geophysical Research Abstracts, Vol.14, EGU2012-12737, EGU General Assembly 2012

  9. 75 FR 34062 - Airworthiness Directives; Eurocopter France Model AS 350 B, BA, B1, B2, B3, and D, and Model...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-16

    ... Airworthiness Directives; Eurocopter France Model AS 350 B, BA, B1, B2, B3, and D, and Model AS355 E, F, F1, F2... AS 350 B, BA, B1, B2, B3, and D, and Model AS355 E, F, F1, F2, and N helicopters, with certain main... an unsafe condition for certain Eurocopter France Model AS 350 B, BA, BB, B1, B2, B3, and D, and...

  10. Concentrating Solar Power Projects in France | Concentrating Solar Power |

    Science.gov Websites

    ;alphabetical by project name. You can browse a project profile by clicking on the project name. eLLO Solar NREL France Concentrating solar power (CSP) projects in France are listed belowâ€"

  11. [Seasonal variation patterns of NH4(+) -N/NO3(-) -N ratio and delta 15 NH4(+) value in rainwater in Yangtze River Delta].

    PubMed

    Xie, Ying-Xin; Zhang, Shu-Li; Zhao, Xu; Xiong, Zheng-Qin; Xing, Guang-Xi

    2008-09-01

    By using a customized manual rainwater sampler made of polyvinyl chloride plastic, the molar ratio of NH4(+) -N/NO3(-) -N and the natural 15N abundance of NH4(+) (delta 15 NH4(+) in rainwater was monitored all year round from June 2003 to July 2005 at three observation sites (Changshu, Nanjing, and Hangzhou) in the Yangtze River Delta. The results indicated that at the three sites, the NH4(+) -N/NO3(-) -N ratio and the delta 15 NH4(+) value in rainwater had the similar seasonal variation trend, being more obvious in Changshu (rural monitoring type) site than in Nanjing (urban monitoring type) and Hangzhou (urban-rural monitoring type) sites. The NH4(+) -N/NO3(-) -N ratio peaked from early June to early August, declined gradually afterwards, and reached the bottom in winter; while the delta 15 NH4(+) value was negative from late June to mid-August, turned positive from late August to mid or late November, became negative again when winter dominated from December to March, but turned positive again in next May and negative again in next July. These seasonal variation patterns of NH4(+) -N/NO3(-) -N ratio and delta 15 NH4(+) value were found in relation to the application of chemical nitrogen fertilizers during different crop growth periods, and also, the alternation of seasons and the NH3 volatilization from other NH3 emission sources (including excrements of human and animals, nitrogen- polluted water bodies, and organic nitrogen sources, etc.), which could be taken as an indicator of defining the sources and form composition of NH4(+) in atmospheric wet deposition and the intensity of various terrestrial NH3 emission sources.

  12. Anaphylaxis to diclofenac: nine cases reported to the Allergy Vigilance Network in France.

    PubMed

    Picaud, J; Beaudouin, E; Renaudin, J M; Pirson, F; Metz-Favre, C; Dron-Gonzalvez, M; Moneret-Vautrin, D A

    2014-10-01

    Nine cases of diclofenac hypersensitivity recorded by the Allergy Vigilance Network in France from 2002 to 2012 were studied. Data from history, symptoms, skin tests, basophil activation tests, and oral challenge (OC) were recorded. Grade 3 severe anaphylactic reactions occurred in seven cases of nine. IgE-dependent anaphylaxis was confirmed in six cases: positive intradermal tests (n = 4), a syndromic reaction during skin tests (n = 1), and one case with grade 1 reaction and negative skin tests had an anaphylactic shock to the OC. A nonimmune reaction was suspected in one case. An IgE-dependent mechanism may be the predominant cause of adverse reactions to diclofenac. Allergy skin tests must be carried out sequentially at the recommended concentrations. BATs may be helpful because they can support the diagnosis of anaphylaxis. Given the risks of a direct challenge to diclofenac, OC to aspirin should be performed first to exclude a nonimmunologic hypersensitivity to NSAIDs. Tests for specific IgEs to most frequently used NSAIDs such as diclofenac and ibuprofen are urgently needed. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  13. Consumers' acceptance of innovations in traditional cheese. A comparative study in France and Norway.

    PubMed

    Almli, Valérie Lengard; Naes, Tormod; Enderli, Géraldine; Sulmont-Rossé, Claire; Issanchou, Sylvie; Hersleth, Margrethe

    2011-08-01

    This study explores consumers' acceptance of innovations in traditional cheese in France (n=120) and Norway (n=119). The respondents were presented with 16 photographs of a traditional cheese from their respective countries, varying according to six factors: pasteurisation, organic production, omega-3, packaging, price and appropriateness. For each of the scenarios the consumers indicated their willingness to buy the cheese on a nine-point scale. Results show that consumers' willingness to buy traditional cheese is highly driven by price, appropriateness and pasteurisation in both countries. However, on average consumers in the French sample prefer buying raw milk cheese, while consumers in the Norwegian sample prefer buying pasteurised cheese. These general trends are led by a pro-raw milk segment in France and a pro-pasteurised milk segment in Norway. Several interaction effects involving appropriateness are detected, indicating the importance of the consumption context on the acceptance of innovations in traditional cheese. On a general level, the results indicate that well-accepted innovations in traditional cheese are those that reinforce the traditional and authentic character of the product. Copyright © 2011 Elsevier Ltd. All rights reserved.

  14. La punaise diabolique a la conquete de la France

    USDA-ARS?s Scientific Manuscript database

    Halyomorpha halys is now present in France in Alsace and in several neighboring countries (Switzerland and Italy). The potential risk of invasion of H. halys throughout France is considered to be high. Through its natural dispersal, or with human assistance, this insect will likely colonize the majo...

  15. Downscaling and hydrological uncertainties in 20th century hydrometeorological reconstructions over France

    NASA Astrophysics Data System (ADS)

    Vidal, Jean-Philippe; Caillouet, Laurie; Dayon, Gildas; Boé, Julien; Sauquet, Eric; Thirel, Guillaume; Graff, Benjamin

    2017-04-01

    The record length of streamflow observations is generally limited to the last 50 years, which is not enough to properly explore the natural hydrometeorological variability, a key to better understand the effects of anthropogenic climate change. This work proposes a comparison of different hydrometeorological reconstruction datasets over France built on the downscaling of the NOAA 20th century global extended reanalysis (20CR, Compo et al., 2011). It aims at assessing the uncertainties related to these reconstructions and improving our knowledge of the multi-decadal hydrometeorological variability over the 20th century. High-resolution daily meteorological reconstructions over the period 1871-2012 are obtained with two statistical downscaling methods based on the analogue approach: the deterministic ANALOG method (Dayon et al., 2015) and the probabilistic SCOPE method (Caillouet et al., 2016). These reconstructions are then used as forcings for the GR6J lumped conceptual rainfall-runoff model and the SIM physically-based distributed hydrological model, in order to derive daily streamflow reconstructions over a set of around 70 reference near-natural catchments. Results show a large multi-decadal streamflow variability over the last 140 years, which is however relatively consistent over France. Empirical estimates of three types of uncertainty - structure of the downscaling method, small-scale internal variability, and hydrological model structure - show roughly equal contributions to the streamflow uncertainty at the annual time scale, with values as high as 20% of the interannual mean. Caillouet, L., Vidal, J.-P., Sauquet, E., and Graff, B.: Probabilistic precipitation and temperature downscaling of the Twentieth Century Reanalysis over France, Clim. Past, 12, 635-662, doi:10.5194/cp-12-635-2016, 2016. Compo, G. P., Whitaker, J. S., Sardeshmukh, P. D., Matsui, N., Allan, R. J., Yin, X., Gleason, B. E., Vose, R. S., Rutledge, G., Bessemoulin, P., Brönnimann, S

  16. ADULT EDUCATION IN FRANCE.

    ERIC Educational Resources Information Center

    TITMUS, COLIN J.

    A SURVEY OF NONVOCATIONAL ADULT EDUCATION IN FRANCE, THE FIRST FULL LENGTH STUDY, OUTLINES ITS HISTORY FROM THE FRENCH REVOLUTION THROUGH THE RESISTANCE, THE PRINCIPLES AND CONDITIONS OF POPULAR EDUCATION SINCE 1945, LOCAL AND GOVERNMENTAL PROGRAMS, SERVICES OF PRIVATE AND GENERAL ORGANIZATIONS, PROVISIONS FOR SPECIAL INTERESTS AND GROUPS,…

  17. Assessment and diffusion of medical innovations in France: an overview.

    PubMed

    Dubromel, Amélie; Geffroy, Loïc; Aulagner, Gilles; Dussart, Claude

    2018-01-01

    Background: In France, a significant part of health expenditure is publicly funding. This put a heavy burden on society. In an economic context requiring tight control of public spending, it seems relevant to control the diffusion of medical innovations. That is why health technology assessment is subject to an increasing interest at national level for management and approval decisions. This article provides an overview of the assessment and diffusion of medical innovation in France. Method: The data are extracted from French authorities or organisations websites and documents and from French legislative texts. In addition, regarding discussion, a search in MEDLINE database was carried out. Results: An overview of the assessment and diffusion of medical innovation in France is given by presenting the different types of medical innovations according to French health system definition (I); introducing French authorities participating to health technology assessment and describe assessment procedures of medical innovations (II); and giving details about market access process of innovative health product in France (III). Key opportunities and challenges of medical innovation assessment and diffusion in France are discussed at the end of this article. Conclusion: In France, medical innovation is considered as a crucial component for quality of care and performance of healthcare system. The aim of health technology assessment is to promote a secure and timely access to innovation for patients. Nevertheless, it appears necessary to improve regulatory mechanisms.

  18. [Health and politics in France].

    PubMed

    Tabuteau, Didier

    2012-06-01

    Health is a dual notion. It is individual, singular and intimate. It is also collective, statistical and political. The modern problematic of health relies upon a balance of complex relations between individual and collective acceptances of the notion. You can try to outline the evolutions and the main concepts through a quadruple approach: health and politics, health and its professionals, health and society and in the end, health and the State. The relationships between health and politics in France are affected by the historical delay of France in public health, namely because of a structural weakness of the administrative organization of public health. Nevertheless France developed a dense and well organized care system and a universal social protection against the disease. The creation of the health professions in France was marked by a historical opposition between the doctors and the state which led to a failure of hygienist medicine and a fundamental misunderstanding on health insurance. Medical domination led to the organization of a system based on professional dichotomy and the delegation of the regulation skills to the health care professionals. The role of health issues in the French society was deeply renewed by the development of the medical and epidemiological knowledge. This resulted in a new political responsibility in the management of health risks but also in the confirmation of the patients' rights and the role of their associations in the health systems operations and the piloting of public policies. In this environment, the state has recently and progressively confirmed its dominating role in the health sector. A public hospital service was created In the 60's and 70's, then in the 80's there were recurrent interventions in order to control health spendings and eventually in the 90's health safety devices were set up. More recently, a process of health policies institutionalization confirmed this evolution. In the future, health issues should

  19. Range Finding 14-Day and 90-Day Subchronic Feeding Studies with N,N-Dipropylcyclohexanecarboxamide in Rats. Phase 4.

    DTIC Science & Technology

    1986-12-01

    Y CLS$1F-.AT N OF THIS...1 MN cD jO 0 -O Ocn00 ~ c" W) 400’ rno n + a9 .9 .i , vi 4 -W cm C44. y c 000 CD %D 1% CD-. U 4 CnN C! - N ON N N TV o 00 e~. r, ML 4r WL ne 0...to N D N4 ’aN N " Nf Y N Nm 00 1C’ bq D Wc iG f". rC W C4 No N N D On ’-0 0 0 f" .4l cc W.4 LoP doE N 04 In Ins. +. V. 0 0 fn 10 C Go 0D C 00’ 4o

  20. 75 FR 53857 - Airworthiness Directives; Eurocopter France Model SA330J Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-02

    ... Airworthiness Directives; Eurocopter France Model SA330J Helicopters AGENCY: Federal Aviation Administration... known U.S. owners and operators of Eurocopter France (Eurocopter) Model SA330J helicopters by individual...'' rather than checking for ``play.'' This helicopter model is manufactured in France and is type...

  1. 75 FR 42380 - Revocation of Antidumping Duty Order on Sorbitol From France

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-21

    ... Duty Order on Sorbitol From France AGENCY: Import Administration, International Trade Administration... sunset review of the antidumping duty order on sorbitol from France. See Initiation of Five-year... the existing antidumping duty order on sorbitol from France would not be likely to lead to...

  2. [A case of donovanosis acquired in France].

    PubMed

    Okhremchuk, I; Marmottant, E; Abed, S; Nguyen, A-T; Fournier, B; Boye, T; Morand, J-J

    2016-11-01

    Donovanosis (granuloma inguinale) is a bacterial infection caused by Klebsiella granulomatis that occurs mainly in the genital area and is primarily sexually transmitted; it is seen predominantly in the tropics. Herein, we report a case of the disease contracted in metropolitan France. A 47-year-old man presented with painless ulceration of the glans, present for one month, with progressive extension; there was no history of any recent trip abroad. Skin biopsy with Whartin-Starry and Giemsa staining revealed Donovan bodies in the cytoplasm of macrophages. Based on these findings, further questioning of the patient revealed unprotected sexual contact two months earlier in France. Treatment was initiated with azithromycin 1g on the first day followed by 500mg per day for three weeks. The clinical outcome was spectacular, with almost complete regression of the ulcer at 7 days. This case demonstrates that donovanosis can occur in metropolitan France. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

  3. "Franklin: Science, Politics and France"

    NASA Astrophysics Data System (ADS)

    McClellan, James E., III

    2003-04-01

    This presentation traces Benjamin Franklin's career as a "civic scientist" in Old-Regime France. It outlines the initial - and not always positive - reception of Franklin's work on electricity by the community of French scientists in the 1750s. It sketches Franklin's subsequent elevation into the pantheon of French Enlightenment heros, and it details his work as a "civic scientist" while American envoy to France in the 1770s and 1780s, notably his service on the government-sponsored commissions that repudiated the scientific and medical claims of Franz Anton Mesmer. This presentation concludes by examining a few features of Franklin's career that are not completely congruent with our notion of what a "civic scientist" might be, a contrast that is intended to illuminate both Franklin and the concept of "civic scientist."

  4. The Definition of Vocational Diplomas in Germany and France.

    ERIC Educational Resources Information Center

    Mobus, Martine; Verdier, Eric

    1997-01-01

    In both France and Germany, the government, employers' organizations, and unions all participate in defining vocational diplomas based on a national framework of procedures of elaborating and standardizing titles. Important differences between the diploma definition processes in France and Germany may be identified. In Germany, the issue is…

  5. 76 FR 81430 - Airworthiness Directives; Eurocopter France (Eurocopter) Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-28

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 39 [Docket No. FAA-2011-1408; Directorate Identifier 2008-SW-10-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France... [Amended] 2. The FAA amends Sec. 39.13 by adding the following new AD: Eurocopter France: Docket No. FAA...

  6. Validation of Tropospheric Water Vapor as Measured by the 183-GHz Radiometer HAMSTRAD with IASI and Sondes over the Pyrenees Mountains, France

    NASA Astrophysics Data System (ADS)

    Ricaud, P.; Drasin, O.; Gabard, B.; Derrien, S.; Attie, J.-L.; Rose, T.; Czekala, H.

    The HAMSTRAD 183-GHz radiometer has been developed to measure vertical profiles of water vapor above the Dome C (Concordia Station), Antarctica (75°06'S, 123°21'E, 3233 m asml), an extremely cold and dry environment, over decades. Prior to its installation at Dome C in January 2009, the instrument was deployed at the Pic du Midi (PdM) station (42°56'N, 0°08'E, 2877 m asml, France) in the Pyrenees Mountains over the period February-June 2008. Vertical profiles of absolute humidity and Integrated Water Content (IWV) as measured by HAMSTRAD were compared with measurements from radio-sondes launched in three different sites: Lannemezan (43°07'N, 0°23'E, 610 m asml, France) [ 30 km North-East from PdM], Bordeaux-Mérignac Airport (44°49'N, 0°42'W, 50 m asml, France) [ 220 km North-West from PdM], and Zaragoza (41°39'N, 0°53'W, 263 m asml, Spain) [ 170 km South-West from PdM]. The validation process also used the vertical profiles of tropospheric H2O as measured by the nadir-viewing Infrared Atmospheric Sounding Interferometer (IASI) instrument aboard the MetOp-A space platform. The temporal evolution of the HAMSTRAD H2O measurements above the PdM station is very consistent with IASI, sondes, and in situ measurements, tracking the same atmosphere from a dry period in February to a wet period in June. HAMSTRAD showed unrealistic values in periods of well established snow tempest. Whilst the sensitivity of the HAMSTRAD measurements tends to be lost 6 km above the altitude of the instrument, namely above 8877 m asml, the HAMSTRAD measurements seem reasonable at the uppermost retrieval level (namely 10 km, 12877 m asml). In May 2008, the wet periods are systematically showing a good agreement between sondes and HAMSTRAD IWV fields and H2O below 6777 m asml, but a dry bias of-2IASI by more than 4 kg m IWV whilst, outside ofthese periods, the 3 data sets behave consistently.

  7. The Marketisation of Guidance Services in Germany, France and Britain.

    ERIC Educational Resources Information Center

    Rees, Teresa; Bartlett, Will; Watts, A. G.

    1999-01-01

    Compares developments in Britain, France, and Germany, focusing on the trends toward marketing adult career guidance services. Describes how Germany's centralized system and the quasi-market based system in France might apply in Britain. (JOW)

  8. [Hospital emergency and health system organization in France].

    PubMed

    Moreau, François

    2003-01-01

    There is no legal definition of the term "emergency" in France. Given the vagueness of this term, a law was passed on 6 January 1986 in France defining the principle of urgent medical assistance as "providing the sick, the wounded and pregnant women, wherever they are, with the appropriate emergency care to meet their condition". The Ethical Medical Code of 6 September 1995 (Art. 77) specifies that "regarding constant availability of health care, the duty of every doctor is to take part in the day and night on-call rota". To understand the emergency care system in France, it should be stressed that the health system is a joint system, with a private sector and a public sector jointly organizing and providing health care. The patient can access either system as he chooses.

  9.  Autochthonous infection with hepatitis E virus related to subtype 3a, France: a case report.

    PubMed

    Saint-Jacques, Pauline; Tissot-Dupont, Hervé; Colson, Philippe

    2016-01-01

    Hepatitis E virus (HEV) recently emerged in Europe as a cause of autochthonous acute hepatitis and a porcine zoonosis. European autochthonous cases almost exclusively involved viruses of genotype 3, subtype 3a being only recently reported in France, from farm pigs. We report an autochthonous human infection with a HEV related to subtype 3a in Southeastern France. A 55-year-old human immunodeficiency virus-infected man presented liver cytolysis in June 2014. HEV RNA was detected in serum and three months later, anti-HEV IgM and IgG were positive whereas HEV RNA was no more detectable in serum. No biological or clinical complication did occur. HEV phylogeny based on two capsid gene fragments showed clustering of sequences obtained from the case-patient with HEV-3a, mean nucleotide identity being 91.7 and 91.3% with their 10 best GenBank matches that were obtained in Japan, South Korea, USA, Canada, Germany and Hungria from humans, pigs and a mongoose. Identity between HEV sequence obtained here and HEV-3a sequences obtained at our laboratory from farm pigs sampled in 2012 in Southeastern France was only 90.2-91.4%. Apart from these pig sequences, best hits from France were of subtypes 3i, 3f, or undefined. The patient consumed barely cooked wild-boar meat; no other risk factor for HEV infection was documented. In Europe, HEV-3a has been described in humans in England and Portugal, in wild boars in Germany, and in pigs in Germany, the Netherlands, and, recently, France. These findings suggest to gain a better knowledge of HEV-3a circulation in France.

  10. 76 FR 75772 - Airworthiness Directives; Eurocopter France Model EC 120B Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-05

    ... Airworthiness Directives; Eurocopter France Model EC 120B Helicopters AGENCY: Federal Aviation Administration... the Eurocopter France Model EC 120B helicopters. This AD requires modifying the pilot cyclic control... include an AD that would apply to Eurocopter France Model EC 120B helicopters. That NPRM was published in...

  11. Chemical composition of fogwater in an urban area: Strasbourg (France).

    PubMed

    Millet, M; Sanusi, A; Wortham, H

    1996-01-01

    To investigate the acidity and to identify the predominant compounds, this work presents the chemical analysis of 18 fogwater samples collected during the year 1991 in Strasbourg, in the east of France. For each fog event, two droplet size categories (2-6 microm and 5-8 microm) have been separately collected and 16 ionic components have been analysed. These two fraction sizes were chosen because they correspond approximately to the size range that can penetrate the human lung and they may have possible health effects. The dominant species were NH4+, NO3-, SO4(2-) and Cl-, with a maximum level of 12,640, 17,270, 21,620 and 13,540 microeq litre(-1), respectively. For most of the fog events the highest concentrations of all analysed species were observed in the 2-6 microm droplets. pH values ranged between 2.79 and 5.70 and the fogwater acidity was governed by three strong acids, H2SO4, HNO3 and HCl and was partially neutralised by NH3 and probably by the presence of CaCO3 in the 'loess', which is the major constituent of soils in the upper Rhine valley. In other respects the acetate/formate ratio (methanoate/ethanoate), generally lower than 1, indicates an important pollution due to automobile exhaust, although the Pb concentrations are moderate due to the general use of unleaded gasoline in France since 1989.

  12. Role of N-acetyltransferase 2 acetylation polymorphism in 4, 4'-methylene bis (2-chloroaniline) biotransformation.

    PubMed

    Hein, David W; Zhang, Xiaoyan; Doll, Mark A

    2018-02-01

    Arylamine N-acetyltransferase 1 (NAT1) and 2 (NAT2) catalyze the acetylation of arylamine carcinogens. Single nucleotide polymorphisms in the NAT2 coding exon present in NAT2 haplotypes encode allozymes with reduced N-acetyltransferase activity towards the N-acetylation of arylamine carcinogens and the O-acetylation of their N-hydroxylated metabolites. NAT2 acetylator phenotype modifies urinary bladder cancer risk following exposures to arylamine carcinogens such as 4-aminobiphenyl. 4, 4'-methylene bis (2-chloroaniline) (MOCA) is a Group 1 carcinogen for which a role of the NAT2 acetylation polymorphism on cancer risk is unknown. We investigated the role of NAT2 and the genetic acetylation polymorphism on both MOCA N-acetylation and N-hydroxy-MOCA O-acetylation. MOCA N-acetylation exhibited a robust gene dose response in rabbit liver cytosol and in cryopreserved human hepatocytes derived from individuals of rapid, intermediate and slow acetylator NAT2 genotype. MOCA exhibited about 4-fold higher affinity for recombinant human NAT2 than NAT1. Recombinant human NAT2*4 (reference) and 15 variant recombinant human NAT2 allozymes catalyzed both the N-acetylation of MOCA and the O-acetylation of N-hydroxy-MOCA. Human NAT2 5, NAT2 6, NAT2 7 and NAT2 14 allozymes catalyzed MOCA N-acetylation and N-hydroxy-O-acetylation at rates much lower than the reference NAT2 4 allozyme. In conclusion, our results show that NAT2 acetylator genotype has an important role in MOCA metabolism and suggest that risk assessments related to MOCA exposures consider accounting for NAT2 acetylator phenotype in the analysis. Copyright © 2017 Elsevier B.V. All rights reserved.

  13. The Molybdenum(V) and Tungsten(VI) Oxoazides [MoO(N3 )3 ], [MoO(N3 )3 ⋅2 CH3 CN], [(bipy)MoO(N3 )3 ], [MoO(N3 )5 ](2-) , [WO(N3 )4 ], and [WO(N3 )4 ⋅CH3 CN].

    PubMed

    Haiges, Ralf; Skotnitzki, Juri; Fang, Zongtang; Dixon, David A; Christe, Karl O

    2015-12-14

    A series of novel molybdenum(V) and tungsten(VI) oxoazides was prepared starting from [MOF4 ] (M=Mo, W) and Me3 SiN3 . While [WO(N3 )4 ] was formed through fluoride-azide exchange in the reaction of Me3 SiN3 with WOF4 in SO2 solution, the reaction with MoOF4 resulted in a reduction of Mo(VI) to Mo(V) and formation of [MoO(N3 )3 ]. Carried out in acetonitrile solution, these reactions resulted in the isolation of the corresponding adducts [MoO(N3 )3 ⋅2 CH3 CN] and [WO(N3 )4 ⋅CH3 CN]. Subsequent reactions of [MoO(N3 )3 ] with 2,2'-bipyridine and [PPh4 ][N3 ] resulted in the formation and isolation of [(bipy)MoO(N3 )3 ] and [PPh4 ]2 [MoO(N3 )5 ], respectively. Most molybdenum(V) and tungsten(VI) oxoazides were fully characterized by their vibrational spectra, impact, friction and thermal sensitivity data and, in the case of [WO(N3 )4 ⋅CH3 CN], [(bipy)MoO(N3 )3 ], and [PPh4 ]2 [MoO(N3 )5 ], by their X-ray crystal structures. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  14. Applications of Subleading-Color Amplitudes in N = 4 SYM Theory

    DOE PAGES

    Naculich, Stephen G.; Nastase, Horatiu; Schnitzer, Howard J.

    2011-01-01

    A numore » mber of features and applications of subleading-color amplitudes of N = 4 SYM theory are reviewed. Particular attention is given to the IR divergences of the subleading-color amplitudes, the relationships of N = 4 SYM theory to N = 8 supergravity, and to geometric interpretations of one-loop subleading-color and N k MHV amplitudes of N = 4 SYM theory.« less

  15. Getting Skills Right: France

    ERIC Educational Resources Information Center

    OECD Publishing, 2017

    2017-01-01

    This report identifies effective strategies to tackle skills imbalances in France. It provides an assessment of practices and policies in the following areas: the collection and use of information on skill needs to foster a better alignment of skills acquisitions with labour market needs; policies stimulating skills demand and skills use; policies…

  16. The association between asthma control, health care costs, and quality of life in France and Spain

    PubMed Central

    2013-01-01

    Background Current asthma management guidelines are based on the level of asthma control. The impact of asthma control on health care resources and quality of life (QoL) is insufficiently studied. EUCOAST study was designed to describe costs and QoL in adult patients according to level of asthma control in France and Spain. Methods An observational cost of illness study was conducted simultaneously in both countries among patients age greater or equal to 18 with a diagnosis of asthma for at least 12 months. Patients were recruited prospectively by GPs in 2010 in four waves to avoid a seasonal bias. Health care resources utilization of the three months before the inclusion was collected through physician questionnaires. Asthma control was evaluated using 2009 GINA criteria over a 3-month period. QoL was assessed using EQ-5D-3L®. Results 2,671 patients (France: 1,154; Spain: 1,517) were enrolled. Asthma was controlled in 40.6% [95% CI: 37.7% - 43.4%] and 29.9% [95% CI: 27.6% - 32.3%] of French and Spanish patients respectively. For all types of costs, the percentage of patients using health care resources varied significantly according to the level of asthma control. The average cost (euros/3-months/patient) of controlled asthma was €85.4 (SD: 153.5) in France compared with €314.0 (SD: 2,160.4) for partially controlled asthma and €537.9 (SD: 2,355.7) for uncontrolled asthma (p<0.0001). In Spain, the corresponding figures were €152.6 (SD: 162.1), €241.2 (SD: 266.8), and €556.8 (SD: 762.4). EQ-5D-3L® score was higher (p<0.0001) in patients with controlled asthma compared to partially controlled and uncontrolled asthma in both countries (respectively 0.88; 0.78; 0.63 in France and 0.89; 0.82; 0.69 in Spain). Conclusions In both countries, patients presenting with uncontrolled asthma had a significantly higher asthma costs and lower scores of Qol compared to the others. PMID:23517484

  17. Environmental assessment of biofuel pathways in Ile de France based on ecosystem modeling.

    PubMed

    Gabrielle, Benoît; Gagnaire, Nathalie; Massad, Raia Silvia; Dufossé, Karine; Bessou, Cécile

    2014-01-01

    The objective of the work reported here was to reduce the uncertainty on the greenhouse gas balances of biofuels using agro-ecosystem modeling at a high resolution over the Ile-de-France region in Northern France. The emissions simulated during the feedstock production stage were input to a life-cycle assessment of candidate biofuel pathways: bioethanol from wheat, sugar-beet and miscanthus, and biodiesel from oilseed rape. Compared to the widely-used methodology based on fixed emission factors, ecosystem modeling lead to 55-70% lower estimates for N2O emissions, emphasizing the importance of regional factors. The life-cycle GHG emissions of first-generation biofuels were 50-70% lower than fossil-based equivalents, and 85% lower for cellulosic ethanol. When including indirect land-use change effects, GHG savings became marginal for biodiesel and wheat ethanol, but were positive due to direct effects for cellulosic ethanol. Copyright © 2013 Elsevier Ltd. All rights reserved.

  18. Assessment and diffusion of medical innovations in France: an overview

    PubMed Central

    Dubromel, Amélie; Geffroy, Loïc; Aulagner, Gilles; Dussart, Claude

    2018-01-01

    ABSTRACT Background: In France, a significant part of health expenditure is publicly funding. This put a heavy burden on society. In an economic context requiring tight control of public spending, it seems relevant to control the diffusion of medical innovations. That is why health technology assessment is subject to an increasing interest at national level for management and approval decisions. This article provides an overview of the assessment and diffusion of medical innovation in France. Method: The data are extracted from French authorities or organisations websites and documents and from French legislative texts. In addition, regarding discussion, a search in MEDLINE database was carried out. Results: An overview of the assessment and diffusion of medical innovation in France is given by presenting the different types of medical innovations according to French health system definition (I); introducing French authorities participating to health technology assessment and describe assessment procedures of medical innovations (II); and giving details about market access process of innovative health product in France (III). Key opportunities and challenges of medical innovation assessment and diffusion in France are discussed at the end of this article. Conclusion: In France, medical innovation is considered as a crucial component for quality of care and performance of healthcare system. The aim of health technology assessment is to promote a secure and timely access to innovation for patients. Nevertheless, it appears necessary to improve regulatory mechanisms. PMID:29686802

  19. [Attractiveness of France for clinical trials: evaluation of laboratories and promoters].

    PubMed

    d'Enfert, Jérôme; Lassale, Catherine; Prod'homme, Pauline

    2003-01-01

    Questions have been raised regarding the attractiveness of France versus other countries for performing clinical trials. A questionnaire was sent to pharmaceutical companies with offices in France to assess their level of activity and to get information on the pros and cons of performing phase I-IV international clinical trials in France. Eleven companies, of large to medium size and representing 44% of the shared market returned answers. In 2001, they spent 131 million euros on clinical trials--53% for phase I-III, with a staff of 1469 (not including Contact Research Organisations)--and involved 21,000 investigators recruiting 98,000 patients on local budgets, and 2257 investigators recruiting 10,270 patients on international budgets. France ranked well as regards size of market or resource availability, with an intermediate rank as regards costs, access to patients and disease prevalence, and was weak with regard to speed of recruitment and quality of investigators. Ways of improving France's attractiveness will be discussed.

  20. Highly Corrosion Resistant and Sandwich-like Si3N4/Cr-CrNx/Si3N4 Coatings Used for Solar Selective Absorbing Applications.

    PubMed

    Zhang, Ke; Du, Miao; Haoa, Lei; Meng, Jianping; Wang, Jining; Mi, Jing; Liu, Xiaopeng

    2016-12-14

    Highly corrosion resistant, layer-by-layer nanostructured Si 3 N 4 /Cr-CrN x /Si 3 N 4 coatings were deposited on aluminum substrate by DC/RF magnetron sputtering. Corrosion resistance experiments were performed in 0.5, 1.0, 3.0, and 5.0 wt % NaCl salt spray at 35 °C for 168 h. Properties of the coatings were comprehensively investigated in terms of optical property, surface morphology, microstructure, elemental valence state, element distribution, and potentiodynamic polarization. UV-vis-near-IR spectrophotometer and FTIR measurements show that the change process in optical properties of Si 3 N 4 /Cr-CrN x /Si 3 N 4 /Al coatings can be divided into three stages: a rapid active degradation stage, a steady passivation stage, and a transpassivation degradation stage. With the increase in the concentration of NaCl salt spray, solar absorptance and thermal emittance experienced a slight degradation. SEM images reveal that there is an increase in surface defects, such as microcracks and holes and -cracks. XRD and TEM measurements indicate that the phase structure changed partially and the content of CrO x and Al 2 O 3 has increased. Auger electron spectroscopy shows that the elements of Cr, N, and O have undergone a minor diffusion. Electrochemical polarization curves show that the as-deposited Si 3 N 4 /Cr-CrN x /Si 3 N 4 /Al coatings have excellent corrosion resistance of 3633.858 kΩ, while after corroding in 5.0 wt % NaCl salt spray for 168 h the corrosion resistance dropped to 13.759 kΩ. However, these coatings still have an outstanding performance of high solar absorptance of 0.924 and low thermal emittance of 0.090 after corroding in 3.0 wt % NaCl salt spray for 120 h. Thus, the Si 3 N 4 /Cr-CrN x /Si 3 N 4 /Al coating is a good choice for solar absorber coatings applied in the high-saline environment.

  1. When and What Meteorological Stresses Will Maize Crops Meet in the future in France?

    NASA Astrophysics Data System (ADS)

    Caubel, J.

    2015-12-01

    Climate change is expected to modify overall climatic conditions and therefore, suitability for cropping. Assessment of when and what meteorological stresses will crops meet in the future is highly useful for planners and land managers who can apply adaptation strategies to improve agricultural potentialities. We propose to evaluate the impacts of climate change on suitability for maize cropping in terms of ecophysiology (e.g., heat stress during grain filling), yield quality (e.g., thermal conditions on protein content) and cultural practices performance (e.g., days available for harvest according to risk of waterlogged soil compaction) in two French areas. The Midi-Pyrénées (southern) and Ile-de-France (northern) regions were chosen as representing the two distinct climates when dividing France into southern and northern parts. The Midi-Pyrénées region is a major irrigated maize producer but could become penalizing in the future because of heat and water stress. By contrast, northern France could become a more suitable area thanks to the expected increasing temperature. To confirm our assumptions, we used the method assessment for crop-climate suitability developed in Caubel et al. (2015) and based on the sub-annual analysis of agroclimatic indicators calculated over phenological periods. Indicators have been calculated using climatic data from 1950 to 2100 simulated by the global climate ARPEGE at the meso-scale SAFRAN (8 km resolution) for the two areas and forced by a greenhouse effect corresponding to the SRES A1B scenario (similar to RCP 6.0). The evaluation was done for two distinct varieties in terms of precocity. Agroclimatic indicators characterizing water deficit and water excess impacts on crop were calculated for three soils with contrasting soil water reserves and depths. Finally, the evaluation was performed with a unique sowing date (the current one), and with an optimized sowing date according to water and thermal requirements for emergence

  2. Freeing France: The Allies, the Resistance, and the JEDBURGHs

    DTIC Science & Technology

    2008-01-01

    attack. Grall suggested and SFHQ agreed the signal would be “Le Chapeau de Napoleon est-il toujours a Perros -Guirec?” (“Is Napoleon’s hat still at... Perros - Guirec?”). After an unsuccessful attempt on 4 July, GILES finally parachuted into the French night on 8/9 July from a Carpetbagger B-24.47...9 and Knox, letter. Napolean’s Hat is the name of a rock formation off the coast of France near the town of Perros -Guirec. 38 “FREDERICK, June Moon

  3. Catalytic Silylation of N2 and Synthesis of NH3 and N2H4 by Net Hydrogen Atom Transfer Reactions Using a Chromium P4 Macrocycle.

    PubMed

    Kendall, Alexander J; Johnson, Samantha I; Bullock, R Morris; Mock, Michael T

    2018-02-21

    We report the first discrete molecular Cr-based catalysts for the reduction of N 2 . This study is focused on the reactivity of the Cr-N 2 complex, trans-[Cr(N 2 ) 2 (P Ph 4 N Bn 4 )] (P 4 Cr(N 2 ) 2 ), bearing a 16-membered tetraphosphine macrocycle. The architecture of the [16]-P Ph 4 N Bn 4 ligand is critical to preserve the structural integrity of the catalyst. P 4 Cr(N 2 ) 2 was found to mediate the reduction of N 2 at room temperature and 1 atm pressure by three complementary reaction pathways: (1) Cr-catalyzed reduction of N 2 to N(SiMe 3 ) 3 by Na and Me 3 SiCl, affording up to 34 equiv N(SiMe 3 ) 3 ; (2) stoichiometric reduction of N 2 by protons and electrons (for example, the reaction of cobaltocene and collidinium triflate at room temperature afforded 1.9 equiv of NH 3 , or at -78 °C afforded a mixture of NH 3 and N 2 H 4 ); and (3) the first example of NH 3 formation from the reaction of a terminally bound N 2 ligand with a traditional H atom source, TEMPOH (2,2,6,6-tetramethylpiperidine-1-ol). We found that trans-[Cr( 15 N 2 ) 2 (P Ph 4 N Bn 4 )] reacts with excess TEMPOH to afford 1.4 equiv of 15 NH 3 . Isotopic labeling studies using TEMPOD afforded ND 3 as the product of N 2 reduction, confirming that the H atoms are provided by TEMPOH.

  4. [Courses in microsurgical techniques in France and abroad].

    PubMed

    Alzakri, A; Al-Rajeh, M; Liverneaux, P A; Facca, S

    2014-06-01

    The objective of this work was to determine the state of current training programs for microsurgery in France and abroad. Our survey of microsurgery training programs determined the registration volume, program contents, and number of students in France, and looked at registration volume and teaching time for programs abroad. Data were obtained from the Internet, university administration, those responsible for university diploma programs, and students. There were 18 university diploma programs in microsurgery in France. The average list price was €1,129 for an average of 19 hours of theoretical training and 100 hours of practice. Evaluation methods varied, but all required at least vascular anastomosis in rats. In 2011-2012, 148 students were enrolled and 126 graduated (85% passing rate). Abroad, 16 basic courses were listed in the USA, Europe and Asia. Nine advanced courses were offered. The average price was $1,346 for 36 hours of practice in the basic courses and $1,955 for over 50 hours of training in advanced courses. None of these courses gave out a diploma. Our results show that in France, university diploma programs in microsurgery are heterogeneous and the French College should consider updating them. Globally, a study is underway by the International Microsurgical Simulation Society. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

  5. Long-Term Care Financing: Lessons From France

    PubMed Central

    Doty, Pamela; Nadash, Pamela; Racco, Nathalie

    2015-01-01

    Context An aging population leads to a growing demand for long-term services and supports (LTSS). In 2002, France introduced universal, income-adjusted, public long-term care coverage for adults 60 and older, whereas the United States funds means-tested benefits only. Both countries have private long-term care insurance (LTCI) markets: American policies create alternatives to out-of-pocket spending and protect purchasers from relying on Medicaid. Sales, however, have stagnated, and the market's viability is uncertain. In France, private LTCI supplements public coverage, and sales are growing, although its potential to alleviate the long-term care financing problem is unclear. We explore whether France's very different approach to structuring public and private financing for long-term care could inform the United States’ long-term care financing reform efforts. Methods We consulted insurance experts and conducted a detailed review of public reports, academic studies, and other documents to understand the public and private LTCI systems in France, their advantages and disadvantages, and the factors affecting their development. Findings France provides universal public coverage for paid assistance with functional dependency for people 60 and older. Benefits are steeply income adjusted and amounts are low. Nevertheless, expenditures have exceeded projections, burdening local governments. Private supplemental insurance covers 11% of French, mostly middle-income adults (versus 3% of Americans 18 and older). Whether policyholders will maintain employer-sponsored coverage after retirement is not known. The government's interest in pursuing an explicit public/private partnership has waned under President François Hollande, a centrist socialist, in contrast to the previous center-right leader, President Nicolas Sarkozy, thereby reducing the prospects of a coordinated public/private strategy. Conclusions American private insurers are showing increasing interest in long

  6. Electricite de France`s ALARA policy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stricker, L.; Rollin, P.

    1995-03-01

    In 1992, Electricite de France - EDF decided to improve the degree to which radiological protection is incorporated in overall management of the utility and set itself the objective of ensuring the same level of protection for workers from contractors as for those from EDF. This decision was taken in a context marked by a deterioration in exposure figures for French plants and by the new recommendations issued by the ICRP. This document describes the policy adopted by EDF at both corporate and plant level to meet these objectives, by: (1) setting up management systems which were responsive but notmore » cumbersome; (2) a broad policy of motivation; (3) the development and use of suitable tools. The document then describes some quite positive results of EDF`s ALARA policy, giving concrete examples and analyzing the changes in global indicators.« less

  7. Linguistic Pluralism in France.

    ERIC Educational Resources Information Center

    Laroche, Jacques M.

    This paper suggests that a discussion of linguistic pluralism in France begins by chronicling the emergence of French as the primary language in early French history and the role of linguistic minorities at various periods in French history. It then focuses on growing linguistic activism in the second half of the twentieth century, when the…

  8. Toxoplasma gondii infection in pork produced in France.

    PubMed

    Djokic, V; Blaga, R; Aubert, D; Durand, B; Perret, C; Geers, R; Ducry, T; Vallee, I; Djurkovic Djakovic, O; Mzabi, A; Villena, I; Boireau, P

    2016-04-01

    The aim of this study was to assess the seroprevalence of the Toxoplasma gondii parasite in pork produced in France, and to determine infection risk factors. An innovative survey was designed based on annual numbers of slaughtered pigs from intensive and outdoor farms in France. A total of 1549 samples of cardiac fluids were collected from pig hearts to determine seroprevalence using a Modified Agglutination Test. Of those, 160 hearts were bio-assayed in mice to isolate live parasites. The overall seroprevalence among fattening pigs was 2·9%. The adjusted seroprevalence in pigs from intensive farms was 3·0%; the highest in sows (13·4%); 2·9% in fattening pigs and 2·6% in piglets. Adjusted seroprevalence in fattening animals from outdoor farms was 6·3%. Strains were isolated from 41 animals and all were genotyped by Restriction Fragment Length Polymorphism as type II. Risk-factor analysis showed that the risk of infection was more than three times higher for outdoor pigs, and that sows' risk was almost five times higher than that of fattening animals. This study provides further evidence of extensive pork infection with T. gondii regardless of breeding systems, indicating that farm conditions are still insufficient to guarantee 'Toxoplasma-free pork'.

  9. A new hot spot for tick-borne encephalitis (TBE): A marked increase of TBE cases in France in 2016.

    PubMed

    Velay, Aurélie; Solis, Morgane; Kack-Kack, Wallys; Gantner, Pierre; Maquart, Marianne; Martinot, Martin; Augereau, Olivier; De Briel, Dominique; Kieffer, Pierre; Lohmann, Caroline; Poveda, Jean Dominique; Cart-Tanneur, Emmanuelle; Argemi, Xavier; Leparc-Goffart, Isabelle; de Martino, Sylvie; Jaulhac, Benoit; Raguet, Sophie; Wendling, Marie-Josée; Hansmann, Yves; Fafi-Kremer, Samira

    2018-01-01

    Tick-borne encephalitis virus (TBEV) is a zoonotic agent causing severe encephalitis. In 2016, in Northeastern France, we faced a TBEV infection increase, leading to a warning from the Regional Health Agency. Here, we report the confirmed TBE cases diagnosed between January 2013 and December 2016, with particular emphasis on the year 2016. A total of 1643 blood and cerebrospinal fluid (CSF) samples from everywhere in France, corresponding to 1460 patients, were prospectively tested for anti-TBEV-specific IgM and IgG antibodies by ELISA. Additional 39 blood and CSF samples from patients with suspected Lyme neuroborreliosis were retrospectively investigated. The TBEV seropositivity rate was estimated to 5.89% and 54 patients were diagnosed as TBE-confirmed cases. A significant increase in TBE cases was observed during the year 2016 with 29 confirmed cases, instead of a mean of eight cases during the three previous years (p=0.0006). Six imported cases and 48 autochthonous cases, located in the Alsace region (n=43) and in the Alpine region (n=5) were reported. Forty-six patients experienced neurological impairment. Nine patients showed an incomplete recovery at last follow-up (from 15days to eight months post-infection). TBE diagnosis was performed earlier for patients taken in charge in the Alsace region than those hospitalized elsewhere in France (p=0.0087). Among the 39 patients with suspected Lyme neuroborreliosis retrospectively investigated, one showed a TBEV recent infection. The TBE increase that occurred in France in 2016 highlights the need to improve our knowledge about the true burden of TBEV infection and subsequent long-term outcomes. Copyright © 2017 Elsevier GmbH. All rights reserved.

  10. The macroeconomic impact of pandemic influenza: estimates from models of the United Kingdom, France, Belgium and The Netherlands.

    PubMed

    Keogh-Brown, Marcus Richard; Smith, Richard D; Edmunds, John W; Beutels, Philippe

    2010-12-01

    The 2003 outbreak of severe acute respiratory syndrome (SARS) showed that infectious disease outbreaks can have notable macroeconomic impacts. The current H1N1 and potential H5N1 flu pandemics could have a much greater impact. Using a multi-sector single country computable general equilibrium model of the United Kingdom, France, Belgium and The Netherlands, together with disease scenarios of varying severity, we examine the potential economic cost of a modern pandemic. Policies of school closure, vaccination and antivirals, together with prophylactic absence from work are evaluated and their cost impacts are estimated. Results suggest GDP losses from the disease of approximately 0.5-2% but school closure and prophylactic absenteeism more than triples these effects. Increasing school closures from 4 weeks at the peak to entire pandemic closure almost doubles the economic cost, but antivirals and vaccinations seem worthwhile. Careful planning is therefore important to ensure expensive policies to mitigate the pandemic are effective in minimising illness and deaths.

  11. N-(3-azidophenyl)-N-methyl-N'-([4-1H]- and [4-3H]-1-naphthyl)guanidine. A potent and selective ligand designed as a photoaffinity label for the phencyclidine site of the N-methyl-D-aspartate receptor.

    PubMed

    Gee, K R; Durant, G J; Holmes, D L; Magar, S S; Weber, E; Wong, S T; Keana, J F

    1993-01-01

    A novel radiolabeled photoaffinity ligand has been synthesized for the phencyclidine (PCP) site of the N-methyl-D-aspartate (NMDA) receptor. N-(3-Azidophenyl)-N-methyl-N'-([4-3H]-1-naphthyl)guanidine (13) was prepared with a specific activity of 25 Ci/mmol by diazotization of N-(3-aminophenyl)-N-methyl-N'-([4-3H]-1-naphthyl)guanidine (12) followed by treatment with sodium azide. Guanidine 12 was obtained by catalytic tritiation of N-(4-bromo-1-naphthyl)-N'-methyl-N'-(3-nitrophenyl)guanidine (11). The nontritiated analog 5 of 13 was prepared beginning with N-methyl-N'-1-naphthyl-N-(3-nitrophenyl)guanidine (9). The guanidines 9 and 11 were prepared in moderate yield by the aluminum chloride-catalyzed reaction of N-methyl-3-nitroaniline hydrochloride with 1-naphthylcyanamide and 4-bromo-1-naphthylcyanamide, respectively. Azide 5 showed high selectivity and affinity (IC50 = 100 nM vs [3H]MK801; 3000 nM vs [3H]ditolylguanidine) for the PCP site of the NMDA receptor in guinea pig brain homogenate. Photolabeling experiments with 13, however, failed to radiolabel a significant amount of receptor polypeptide.

  12. Rare Earth 4f Hybridization with the GaN Valence Band

    DTIC Science & Technology

    2012-01-01

    DOS of Ga17GdN18. and Auger-like electrons emitted in a super Coster– Kronig process [52] 4d104fN + hν → [4d94fN+1]∗ → 4d104fN−1 + e−, (2) where...similar, albeit not identical, response for GaN:Er compared to GaN:Gd at the photon energy characteristic for the Er 4d → 4f super Coster– Kronig resonance

  13. Catalytic Silylation of N 2 and Synthesis of NH 3 and N 2H 4 by Net Hydrogen Atom Transfer Reactions Using a Chromium P 4 Macrocycle

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kendall, Alexander J.; Johnson, Samantha I.; Bullock, R. Morris

    We report the first discrete molecular Cr-based catalysts for the reduction of N2. This study is focused on the reactivity of the Cr-N2 complex, trans-[Cr(N2)2(PPh4NBn4)] P4Cr(N2)2, bearing a 16-membered tetraphosphine macrocycle. The architecture of the [16]-PPh4NBn4 ligand is critical to preserve the structural integrity of the catalyst. P4Cr(N2)2 was found to mediate the reduction of N2 by three complementary reaction pathways: (1) Cr-catalyzed reduction of N2 to N(SiMe3)3 by Na and Me3SiCl affording up to 34 equiv N(SiMe3)3; (2) stoichiometric reduction of N2 by protons and electrons. For example, the reaction of cobaltocene (CoCp2) and collidinium triflate (ColH[OTf]) at roommore » temperature to afforded 1.9 equiv of NH3, or at -78 °C to afforded a mixture of NH3 and N2H4; (3) the first example of NH3 formation from the reaction of a terminally bound N2 ligand with a traditional H atom source, TEMPOH, (2,2,6,6-tetramethylpiperidine-1-ol). We found that trans-[Cr(15N2)2(PPh4NBn4)] reacts with excess TEMPOH to afford a 1.4 equiv of 15NH3.« less

  14. [Health status of populations living in French overseas territories in 2012, compared with metropolitan France: An analysis of the national health insurance database].

    PubMed

    Filipovic-Pierucci, A; Rigault, A; Fagot-Campagna, A; Tuppin, P

    2016-06-01

    This study uses healthcare consumption to compare the health status of beneficiaries of the French national health insurance general scheme between individuals living in French overseas territories (FOT) and those living in metropolitan France. Data were extracted from the French national health insurance database (Sniiram) for 2012, using algorithms, 56 groups of diseases and 27 groups of hospital activity were isolated. Standardized morbidity ratio for age and sex (SMR) were used to compare FOT to mainland France. Compared with mainland France, people living in the four FOT had high SMR for diabetes care (Guadeloupe 1.9; Martinique 1.7; Guyane 1.9; La Réunion 2.3), dialysis (2.7; 2.4; 3.8; 4.4), stroke (1.2; 1.1; 2.0; 1.5), and hospitalization for infectious diseases (1.9; 2.5; 2.4; 1.4) and obstetrics (1.4; 1.2; 1.9; 1.2). Care for inflammatory bowel disease or cancer were less frequent except for prostate in Martinique and Guadeloupe (2.3). People living in Martinique, Guadeloupe and la Reunion had more frequently care for psychotic disorders (2.0; 1.7; 1.2), dementia (1.1; 1.3; 11), epileptic seizures (1.4; 1.4; 16) and hospitalizations for burns (2.6; 1.7; 2.9). In la Reunion, people had more frequently coronary syndrome (1.3), cardiac heart failure (1.6), chronic respiratory diseases except cystic fibrosis (1.5), drug addiction (1.4) and hospitalizations for cardiovascular catheterization (1.4) and toxicology, poisoning, alcohol (1.7). Other differences were observed by gender: HIV infection, peripheral arterial disease, some chronic inflammatory disease (lupus) were more frequent in women living in Martinique or Guadeloupe, compared to women from mainland France and psychotic disorders for men. From la Reunion, men had more frequently liver and pancreatic diseases and hospitalisation for toxicology, poisoning, alcohol than men from mainland France. This study highlights the utility of administrative database to compare and follow population health status

  15. Constraining f (R ) Gravity Theory Using Weak Lensing Peak Statistics from the Canada-France-Hawii-Telescope Lensing Survey

    NASA Astrophysics Data System (ADS)

    Liu, Xiangkun; Li, Baojiu; Zhao, Gong-Bo; Chiu, Mu-Chen; Fang, Wei; Pan, Chuzhong; Wang, Qiao; Du, Wei; Yuan, Shuo; Fu, Liping; Fan, Zuhui

    2016-07-01

    In this Letter, we report the observational constraints on the Hu-Sawicki f (R ) theory derived from weak lensing peak abundances, which are closely related to the mass function of massive halos. In comparison with studies using optical or x-ray clusters of galaxies, weak lensing peak analyses have the advantages of not relying on mass-baryonic observable calibrations. With observations from the Canada-France-Hawaii-Telescope Lensing Survey, our peak analyses give rise to a tight constraint on the model parameter |fR 0| for n =1 . The 95% C.L. is log10|fR 0|<-4.82 given WMAP9 priors on (Ωm , As ). With Planck15 priors, the corresponding result is log10|fR 0|<-5.16 .

  16. Potentially inappropriate drug prescription in the elderly in France: a population-based study from the French National Insurance Healthcare system.

    PubMed

    Bongue, B; Laroche, M L; Gutton, S; Colvez, A; Guéguen, R; Moulin, J J; Merle, L

    2011-12-01

    Inappropriate prescribing is a known risk factor for adverse drug event occurrence in the elderly. In various countries, several studies have used insurance healthcare databases to estimate the national prevalence of potentially inappropriate medications (PIM) in the elderly, as defined by explicit PIM lists. Recently, a representative sample of the French National Insurance Healthcare database, known as the "Echantillon Généraliste des Bénéficiaires" (EGB), was created, making it possible to assess the quality of drug prescription in France. Our objective was to evaluate the prevalence and the regional distribution of PIM prescription in the elderly aged 75 years and over in France, using the French PIM list and the EGB database. The list of drugs reimbursed to patients aged 75 years and over from 1 March 2007 to 29 February 2008 was extracted from the EGB. Drugs were classified as inappropriate using the French PIM list. A PIM user was defined as a person receiving at least one PIM reimbursement during the study period. Interregion variability was estimated from logistic regression. In 53.6% (95% CI: 53.0-54.1) of the elderly aged 75 years and over, at least one PIM was given during the study period. The three main drug groups identified were cerebral vasodilators (19.4%), drugs with antimuscarinic properties (19.3%), and long half-life benzodiazepines (17.8%). There was an important disparity in PIM prescription among the French regions. In 14 out of 22 regions, the risk of PIM prescription was significantly elevated. This geographical variation differed for the different drug groups. PIM prescription in the elderly is a major and worrying problem in France. As in other countries, recent accessibility of the National Insurance Healthcare database makes it possible to create local indicators that the regional health agencies could use to manage public health policy in closer alignment to the needs of the patients within each French region.

  17. Synthesis of two-dimensional titanium nitride Ti4N3 (MXene)

    NASA Astrophysics Data System (ADS)

    Urbankowski, Patrick; Anasori, Babak; Makaryan, Taron; Er, Dequan; Kota, Sankalp; Walsh, Patrick L.; Zhao, Mengqiang; Shenoy, Vivek B.; Barsoum, Michel W.; Gogotsi, Yury

    2016-06-01

    We report on the synthesis of the first two-dimensional transition metal nitride, Ti4N3-based MXene. In contrast to the previously reported MXene synthesis methods - in which selective etching of a MAX phase precursor occurred in aqueous acidic solutions - here a molten fluoride salt is used to etch Al from a Ti4AlN3 powder precursor at 550 °C under an argon atmosphere. We further delaminated the resulting MXene to produce few-layered nanosheets and monolayers of Ti4N3Tx, where T is a surface termination (F, O, or OH). Density functional theory calculations of bare, non-terminated Ti4N3 and terminated Ti4N3Tx were performed to determine the most energetically stable form of this MXene. Bare and functionalized Ti4N3 are predicted to be metallic. Bare Ti4N3 is expected to show magnetism, which is significantly reduced in the presence of functional groups.We report on the synthesis of the first two-dimensional transition metal nitride, Ti4N3-based MXene. In contrast to the previously reported MXene synthesis methods - in which selective etching of a MAX phase precursor occurred in aqueous acidic solutions - here a molten fluoride salt is used to etch Al from a Ti4AlN3 powder precursor at 550 °C under an argon atmosphere. We further delaminated the resulting MXene to produce few-layered nanosheets and monolayers of Ti4N3Tx, where T is a surface termination (F, O, or OH). Density functional theory calculations of bare, non-terminated Ti4N3 and terminated Ti4N3Tx were performed to determine the most energetically stable form of this MXene. Bare and functionalized Ti4N3 are predicted to be metallic. Bare Ti4N3 is expected to show magnetism, which is significantly reduced in the presence of functional groups. Electronic supplementary information (ESI) available. See DOI: 10.1039/c6nr02253g

  18. 75 FR 28469 - Airworthiness Directives; Eurocopter France Model AS332L2 Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-21

    ... Airworthiness Directives; Eurocopter France Model AS332L2 Helicopters AGENCY: Federal Aviation Administration.... SUMMARY: We are adopting a new airworthiness directive (AD) for Eurocopter France (Eurocopter) Model... Unsafe Condition Determination This helicopter has been approved by the aviation authority of France and...

  19. Combustion Properties of Amino-Substituted Guanidinium 4,4',5,5'-Tetranitro-2,2'-biimidazolate(N4BIM) Salts

    DOE PAGES

    Tappan, Bryce C.; Chavez, David E.

    2014-12-02

    This paper describes the combustion properties of the amino-substituted guanidinium 4,4’,5,5’-tetranitro-2,2’-biimidazolate (N4BIM) series, including the bis-mono, di and triaminoguanidinium salts. These salts are of interest as propellant ingredient additives, and in particular, the bis-triaminoguanidinium salt of N4BIM displays excellent burn rate and combustion behavior. Our combustion studies have shown that TAGN4-BIM displays a fast burning rate and has the lowest pressure dependence exponent yet measured for a triaminoguanidinium salt.

  20. Descriptive study of the parkinsonian population in the north of France: Epidemiological analysis and healthcare consumption.

    PubMed

    Carriere, N; Verloop, D; Dupont, C; Fontaine, V; Tir, M; Krystkowiak, P; Blanchard, A; Defebvre, M-M; Defebvre, L

    2017-06-01

    The "neurodegenerative diseases plan" under elaboration for the Hauts-de-France region requires better knowledge of the patient population and care pathways. In France, the prevalence of Parkinson's disease (PD) has been estimated from cohorts to be about 1-3 per 1000 inhabitants, but exhaustive data are scarce for the general population. The purpose of this study was to evaluate the prevalence of PD in the Hauts-de-France region and to assess PD-related healthcare consumption. A descriptive study was conducted to identify the parkinsonian population in the Hauts-de-France region (including the administrative districts of Pas-de-Calais and Picardie) for the year 2014. Parkinsonian patients were identified from health insurance fund reimbursement data using the following criteria: (i) reimbursement for a PD-specific medication; (ii) attribution of long-duration disease status coded as PD; (iii) hospital stay with PD diagnosis in the standard discharge report contained in the French medico-economic database on hospital activity (PMSI). The raw prevalence of PD in the region was 5.03 per 1000 inhabitants aged 20 years and older. The standardized prevalence by health territory ranged from 4.0 to 9.0 per 1000 inhabitants aged 20 years and older. During the 1-year study period, 33.5% of patients had a neurology consultation, 57.1% attended a physiotherapy session, and 7.7% received speech therapy. Most of patients (79.6%) were treated with levodopa, sometimes in combination with a catechol-O-methyl transferase inhibitor (14.4%). Dopaminergic agonists were prescribed in 33.5% of cases. A neuroleptic was prescribed for 6.9% of the population (clozapine for 25.9%). The prevalence of PD is high in the Hauts-de-France region with a heterogeneous distribution by health territory. Neurology consultations were attended by a minority of patients in 2014. This work provides perspectives for necessary improvement in specialized care for this disease, both in terms of follow

  1. Crystal structure of bis-(benzyl-amine-κN)[5,10,15,20-tetra-kis-(4-chloro-phen-yl)porphyrinato-κ(4) N]iron(II) n-hexane monosolvate.

    PubMed

    Dhifaoui, Selma; Harhouri, Wafa; Bujacz, Anna; Nasri, Habib

    2016-01-01

    In the title compound, [Fe(II)(C44H24Cl4N4)(C6H5CH2NH2)2]·C6H14 or [Fe(II)(TPP-Cl)(BzNH2)2]·n-hexane [where TPP-Cl and BzNH2 are 5,10,15,20-tetra-kis-(4-chloro-phen-yl)porphyrinate and benzyl-amine ligands, respectively], the Fe(II) cation lies on an inversion centre and is octa-hedrally coordinated by the four pyrrole N atoms of the porphyrin ligand in the equatorial plane and by two amine N atoms of the benzyl-amine ligand in the axial sites. The crystal structure also contains one inversion-symmetric n-hexane solvent mol-ecule per complex mol-ecule. The average Fe-Npyrrole bond length [1.994 (3) Å] indicates a low-spin complex. The crystal packing is sustained by N-H⋯Cl and C-H⋯Cl hydrogen-bonding inter-actions and by C-H⋯π inter-molecular inter-actions, leading to a three-dimensional network structure.

  2. Investigation of the fabrication processes of AlGaN/AlN/GaN HEMTs with in situ Si{sub 3}N{sub 4} passivation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tomosh, K. N., E-mail: sky77781@mail.ru; Pavlov, A. Yu.; Pavlov, V. Yu.

    2016-10-15

    The optimum mode of the in situ plasma-chemical etching of a Si{sub 3}N{sub 4} passivating layer in C{sub 3}F{sub 8}/O{sub 2} medium is chosen for the case of fabricating AlGaN/AlN/GaN HEMTs. It is found that a bias of 40–50 V at a high-frequency electrode provides anisotropic etching of the insulator through a resist mask and introduces no appreciable radiation-induced defects upon overetching of the insulator films in the region of gate-metallization formation. To estimate the effect of in situ Si{sub 3}N{sub 4} growth together with the heterostructure in one process on the AlGaN/AlN/GaN HEMT characteristics, transistors with gates without themore » insulator and with gates through Si{sub 3}N{sub 4} slits are fabricated. The highest drain current of the AlGaN/AlN/GaN HEMT at 0 V at the gate is shown to be 1.5 times higher in the presence of Si{sub 3}N{sub 4} than without it.« less

  3. Occupational, social and medical characteristics of early prenatal leave in France.

    PubMed

    Vigoureux, Solène; Blondel, Béatrice; Ringa, Virginie; Saurel-Cubizolles, Marie-Josèphe

    2016-12-01

    In France, most women of childbearing age work. The prenatal leave law in France protects women during pregnancy and their employment. We aimed to describe how long before delivery women stopped working and analyse the association between occupational, social and medical factors and early prenatal leave (before 24 weeks' gestation). The sample was extracted from the 2010 French National Perinatal Survey. Women were interviewed in French maternity units during a 1-week period. We focused on all women with a singleton live birth who were working during pregnancy (n = 10 149). Women were interviewed between delivery and discharge to collect information on employment, date of leave, sociodemographic and medical characteristics. Among women who worked during pregnancy, 27.5% reported early occupational leave (before 24 weeks' gestation). Early occupational leave was more frequent among women with unstable jobs (fixed-term vs. non-fixed-term contract: adjusted odds ratio aOR = 1.60 [95% confidence interval 1.40-1.84]) and with less-qualified occupational categories (manual workers vs. managers and upper-intellectual positions: aOR = 2.96 [2.30-3.82]), even after adjusting for sociodemographic and other employment characteristics. Women with a pathological or at risk pregnancy left work earlier than other women. After stratification on type of pregnancy there was still a higher rate of early leave for women with less qualified occupational group. In France, social vulnerability of pregnant women, linked to low sociodemographic situation or low occupational categories, is associated with early leave during pregnancy, even after stratification on type of pregnancy. © The Author 2016. Published by Oxford University Press on behalf of the European Public Health Association. All rights reserved.

  4. Crystal structure of poly[[μ-4-(hy-droxy-meth-yl)pyridine-κ(2) N:O][4-(hy-droxy-meth-yl)pyridine-κN](μ-thio-cyanato-κ(2) N:S)(thio-cyanato-κN)cadmium].

    PubMed

    Werner, Julia; Jess, Inke; Näther, Christian

    2015-06-01

    The crystal structure of the title compound, [Cd(NCS)2(C6H7NO)2] n is made up of Cd(2+) cations that are coordinated by three thio-cyanate ligands and three 4-(hy-droxy-meth-yl)pyridine ligands within distorted N4OS octa-hedra. The asymmetric unit consists of one Cd(2+) cation, two thio-cyanate anions and two 4-(hy-droxy-meth-yl)pyridine ligands in general positions. Two Cd(2+) cations are linked by two μ-1,3 N- and S-bonding thio-ycanate anions into dimers which are further linked into branched chains along [100] by two μ-1,6 N- and O-bonding 4-(hy-droxy-meth-yl)pyridine ligands. One additional N-bonded 4-(hy-droxy-meth-yl)pyridine ligand and one additional N-bonded thio-cyanate anion are only terminally bonded to the metal cation. Inter-chain O-H⋯S hydrogen bonds between the hy-droxy H atoms and one of the thio-cyanate S atoms connect the chains into a three-dimensional network.

  5. 76 FR 35346 - Airworthiness Directives; Eurocopter France Model SA-365C, SA-365C1, SA-365C2, SA-365N, SA-365N1...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-17

    ... Eurocopter France (Eurocopter) helicopters. This action requires visually inspecting the adhesive bead between the bushing and the Starflex star (Starflex) arm for a crack, a gap, or loss of the adhesive bead... inspecting the adhesive bead between the bushing and the Starflex arm for a crack, a gap, or loss of the...

  6. Spatiotemporal dynamics of HIV-1 transmission in France (1999-2014) and impact of targeted prevention strategies.

    PubMed

    Chaillon, Antoine; Essat, Asma; Frange, Pierre; Smith, Davey M; Delaugerre, Constance; Barin, Francis; Ghosn, Jade; Pialoux, Gilles; Robineau, Olivier; Rouzioux, Christine; Goujard, Cécile; Meyer, Laurence; Chaix, Marie-Laure

    2017-02-21

    Characterizing HIV-1 transmission networks can be important in understanding the evolutionary patterns and geospatial spread of the epidemic. We reconstructed the broad molecular epidemiology of HIV from individuals with primary HIV-1 infection (PHI) enrolled in France in the ANRS PRIMO C06 cohort over 15 years. Sociodemographic, geographic, clinical, biological and pol sequence data from 1356 patients were collected between 1999 and 2014. Network analysis was performed to infer genetic relationships, i.e. clusters of transmission, between HIV-1 sequences. Bayesian coalescent-based methods were used to examine the temporal and spatial dynamics of identified clusters from different regions in France. We also evaluated the use of network information to target prevention efforts. Participants were mostly Caucasian (85.9%) and men (86.7%) who reported sex with men (MSM, 71.4%). Overall, 387 individuals (28.5%) were involved in clusters: 156 patients (11.5%) in 78 dyads and 231 participants (17%) in 42 larger clusters (median size: 4, range 3-41). Compared to individuals with single PHI (n = 969), those in clusters were more frequently men (95.9 vs 83%, p < 0.01), MSM (85.8 vs 65.6%, p < 0.01) and infected with CRF02_AG (20.4 vs 13.4%, p < 0.01). Reconstruction of viral migrations across time suggests that Paris area was the major hub of dissemination of both subtype B and CRF02_AG epidemics. By targeting clustering individuals belonging to the identified active transmission network before 2010, 60 of the 143 onward transmissions could have been prevented. These analyses support the hypothesis of a recent and rapid rise of CRF02_AG within the French HIV-1 epidemic among MSM. Combined with a short turnaround time for sample processing, targeting prevention efforts based on phylogenetic monitoring may be an efficient way to deliver prevention interventions but would require near real time targeted interventions on the identified index cases and their partners.

  7. Factors associated with overweight in preschool-age children in southwestern France.

    PubMed

    Jouret, Béatrice; Ahluwalia, Namanjeet; Cristini, Christelle; Dupuy, Marie; Nègre-Pages, Laurence; Grandjean, Hélène; Tauber, Maithé

    2007-06-01

    Pediatric overweight and obesity are becoming an epidemic worldwide, which indicates the need for formulating preventive programs and policies during a child's early years. We identified factors associated with overweight in young children in southwestern France. Children [n = 1780; x (+/-SD) age: 3.9 +/- 0.4 y] were recruited in kindergarten. Medical information on the parents, grandparents, and child as well as the child's 3-d dietary intake, participation in organized sports, and television-viewing habits were ascertained, and anthropometric measurements of the child were taken. The prevalence of overweight was 9.1% when using body mass index >or= 90th percentile of French reference curves as a cutoff. In a multivariate logistic regression, overweight at 4 y was associated with female sex, having an overweight mother, and having >or=1 diabetic grandparent; odds ratios (ORs; 95% CIs) for these variables were 1.9 (1.2, 3.0), 2.2 (1.0, 4.7), and 2.6 (1.6, 4.1), respectively. Being small or large for gestational age was not associated with the risk of overweight at 4 y, whereas this risk was increased for children who were overweight at 9 or 24 mo: ORs (95% CIs) were 4.0 (2.4, 6.9) and 11.7 (6.1, 22.2), respectively. Nutrient intakes did not differ significantly with weight status in girls; however, overweight boys had significantly greater energy and lipid intakes than did their nonoverweight counterparts. Overweight was positively associated with television viewing (>1 h/d) in both sexes and with participation in organized sports in girls only. A family history of overweight or diabetes, overweight in the first 2 y of life, and television viewing are associated with overweight at 4 y. These factors should be considered in developing programs for the prevention of overweight in early childhood.

  8. Prevalence and mortality of patients with multiple sclerosis in France in 2012: a study based on French health insurance data.

    PubMed

    Foulon, Stéphanie; Maura, Géric; Dalichampt, Marie; Alla, François; Debouverie, Marc; Moreau, Thibault; Weill, Alain

    2017-06-01

    Data on the prevalence of multiple sclerosis (MS) in France are scarce. National and regional updated estimates are needed to better plan health policies. In this nationwide study, we provided estimates of the prevalence of MS in France in 2012 and mortality rate in 2013. MS cases were identified in the French national health insurance database (SNIIRAM-PMSI) using reimbursement data for disease-modifying treatment, long-term disease status for MS, disability pension for MS, and hospitalisation for MS (MS ICD-10 code: G35). We identified 99,123 MS cases, corresponding to an overall crude prevalence rate of 151.2 per 100,000 inhabitants [95% confidence interval (CI) 150.3-152.2]: 210.0 per 100,000 in women (95% CI 208.4-211.5) and 88.7 per 100,000 in men (95% CI 87.6-89.7). The overall prevalence rate was 155.6 per 100,000 inhabitants (95% CI 154.7-156.6) after standardization on the 2013-European population. We observed a prevalence gradient with a higher prevalence (190-200 per 100,000) in North-Eastern France and a lower prevalence in Southern and Western France (126-140). The crude mortality rate in 2013 was 13.7 per 1,000 MS cases (11.4 in women and 20.3 in men). The standardized mortality ratio was 2.56 (95% CI 2.41-2.72). Our results revise upwards the estimation of MS prevalence in France and confirm the excess mortality of MS patients compared to the general population.

  9. Lipid Composition, Fatty Acids and Sterols in the Seaweeds Ulva armoricana, and Solieria chordalis from Brittany (France): An Analysis from Nutritional, Chemotaxonomic, and Antiproliferative Activity Perspectives

    PubMed Central

    Kendel, Melha; Wielgosz-Collin, Gaëtane; Bertrand, Samuel; Roussakis, Christos; Bourgougnon, Nathalie; Bedoux, Gilles

    2015-01-01

    Lipids from the proliferative macroalgae Ulva armoricana (Chlorophyta) and Solieria chordalis (Rhodophyta) from Brittany, France, were investigated. The total content of lipids was 2.6% and 3.0% dry weight for U. armoricana and S. chordalis, respectively. The main fractions of S. chordalis were neutral lipids (37%) and glycolipids (38%), whereas U. armoricana contained mostly neutral lipids (55%). Polyunsaturated fatty acids (PUFA) represented 29% and 15% of the total lipids in U. armoricana and S. chordalis, respectively. In both studied algae, the phospholipids were composed of PUFA for 18%. In addition, PUFA were shown to represent 9% and 4.5% of glycolipids in U. armoricana and S. chordalis, respectively. The essential PUFA were 16:4n-3, 18:4n-3, 18:2n-3, 18:2n-6, and 22:6n-3 in U. armoricana, and 20:4n-6 and 20:5n-3 in S. chordalis. It is important to notice that six 2-hydroxy-, three 3-hydroxy-, and two monounsaturated hydroxy fatty acids were also identified and may provide a chemotaxonomic basis for algae. These seaweeds contained interesting compounds such as squalene, α-tocopherol, cholest-4-en-3-one and phytosterols. The antiproliferative effect was evaluated in vitro on human non-small-cell bronchopulmonary carcinoma line (NSCLC-N6) with an IC50 of 23 μg/mL for monogalactosyldiacylglycerols isolated from S. chordalis and 24 μg/mL for digalactosyldiacylglycerols from U. armoricana. These results confirm the potentialities of valorization of these two species in the fields of health, nutrition and chemotaxonomy. PMID:26404323

  10. Impossible Neanderthals? Making string, throwing projectiles and catching small game during Marine Isotope Stage 4 (Abri du Maras, France)

    NASA Astrophysics Data System (ADS)

    Hardy, Bruce L.; Moncel, Marie-Hélène; Daujeard, Camille; Fernandes, Paul; Béarez, Philippe; Desclaux, Emmanuel; Chacon Navarro, Maria Gema; Puaud, Simon; Gallotti, Rosalia

    2013-12-01

    Neanderthal behavior is often described in one of two contradictory ways: 1) Neanderthals were behaviorally inflexible and specialized in large game hunting or 2) Neanderthals exhibited a wide range of behaviors and exploited a wide range of resources including plants and small, fast game. Using stone tool residue analysis with supporting information from zooarchaeology, we provide evidence that at the Abri du Maras, Ardèche, France, Neanderthals were behaviorally flexible at the beginning of MIS 4. Here, Neanderthals exploited a wide range of resources including large mammals, fish, ducks, raptors, rabbits, mushrooms, plants, and wood. Twisted fibers on stone tools provide evidence of making string or cordage. Using a variety of lines of evidence, we show the presence of stone projectile tips, possibly used in complex projectile technology. This evidence shows a level of behavioral variability that is often denied to Neanderthals. Furthermore, it sheds light on perishable materials and resources that are not often recovered which should be considered more fully in reconstructions of Neanderthal behavior.

  11. Fine-scale human genetic structure in Western France.

    PubMed

    Karakachoff, Matilde; Duforet-Frebourg, Nicolas; Simonet, Floriane; Le Scouarnec, Solena; Pellen, Nadine; Lecointe, Simon; Charpentier, Eric; Gros, Françoise; Cauchi, Stéphane; Froguel, Philippe; Copin, Nane; Le Tourneau, Thierry; Probst, Vincent; Le Marec, Hervé; Molinaro, Sabrina; Balkau, Beverley; Redon, Richard; Schott, Jean-Jacques; Blum, Michael Gb; Dina, Christian

    2015-06-01

    The difficulties arising from association analysis with rare variants underline the importance of suitable reference population cohorts, which integrate detailed spatial information. We analyzed a sample of 1684 individuals from Western France, who were genotyped at genome-wide level, from two cohorts D.E.S.I.R and CavsGen. We found that fine-scale population structure occurs at the scale of Western France, with distinct admixture proportions for individuals originating from the Brittany Region and the Vendée Department. Genetic differentiation increases with distance at a high rate in these two parts of Northwestern France and linkage disequilibrium is higher in Brittany suggesting a lower effective population size. When looking for genomic regions informative about Breton origin, we found two prominent associated regions that include the lactase region and the HLA complex. For both the lactase and the HLA regions, there is a low differentiation between Bretons and Irish, and this is also found at the genome-wide level. At a more refined scale, and within the Pays de la Loire Region, we also found evidence of fine-scale population structure, although principal component analysis showed that individuals from different departments cannot be confidently discriminated. Because of the evidence for fine-scale genetic structure in Western France, we anticipate that rare and geographically localized variants will be identified in future full-sequence analyses.

  12. Barrier height modification and mechanism of carrier transport in Ni/in situ grown Si3N4/n-GaN Schottky contacts

    NASA Astrophysics Data System (ADS)

    Karpov, S. Y.; Zakheim, D. A.; Lundin, W. V.; Sakharov, A. V.; Zavarin, E. E.; Brunkov, P. N.; Lundina, E. Y.; Tsatsulnikov, A. F.

    2018-02-01

    In situ growth of an ultra-thin (up to 2.5 nm) Si3N4 film on the top of n-GaN is shown to reduce remarkably the height of the barrier formed by deposition of Ni-based Schottky contact. The reduction is interpreted in terms of polarization dipole induced at the Si3N4/n-GaN interface and Fermi level pinning at the Ni/Si3N4 interface. Detailed study of temperature-dependent current-voltage characteristics enables identification of the electron transport mechanism in such Schottky diodes under forward bias: thermal/field electron emission over the barrier formed in n-GaN followed by tunneling through the Si3N4 film. At reverse bias and room temperature, the charge transfer is likely controlled by Poole-Frenkel ionization of deep traps in n-GaN. Tunneling exponents at forward and reverse biases and the height of the Ni/Si3N4 Schottky barrier are evaluated experimentally and compared with theoretical predictions.

  13. Current status of medical and veterinary entomology in France: endangered discipline or promising science?

    PubMed

    Cuisance, Dominique; Antoine Rioux, Jean

    2004-09-01

    Following alarming statements (French Senate, Académie des Sciences) on the present situation concerning entomology and systematics in France, the Conseil Général Vétérinaire designated one of us (D.C.) to carry out a survey on the status of medical and veterinary entomology (MVE) with respect to research orientations and university curricula. Around 100 participants, including scientists, teachers and several directors of research and educational bodies, were interviewed and filled in questionnaires for this survey. On the basis of the results, it was concluded that the deterioration of MVE in France is associated with: (1) the hasty reorganisation of training and research in the life sciences, leading to the disappearance of several disciplines. Hence, the postgraduate DEA degree in entomology was eliminated, and even the name 'entomology' no longer appears in teaching programmes or on research contracts; (2) France's withdrawal from action research programmes in developing countries. Although these programmes were efficient in controlling outbreaks of major endemic diseases, integrated pest and vector management programmes have been replaced by basic health care ('Health for everyone in 2000') and vaccination programmes; (3) the general shift from field to laboratory research, focused mainly on molecular mechanisms. The survey results confirmed generally acknowledged trends concerning many points and highlighted several specific problems, such as the disappearance of systematics experts. Several potential solutions are proposed.

  14. Changing Pattern of Chlamydia trachomatis Strains in Lymphogranuloma Venereum Outbreak, France, 2010-2015.

    PubMed

    Peuchant, Olivia; Touati, Arabella; Sperandio, Clément; Hénin, Nadège; Laurier-Nadalié, Cécile; Bébéar, Cécile; de Barbeyrac, Bertille

    2016-11-01

    We describe a change in the molecular epidemiology of Chlamydia trachomatis strains involved in an outbreak of rectal lymphogranuloma venereum in France during January 2010-April 2015. Until 2012, the C. trachomatis L2b strain predominated; however, starting in 2013, most cases involved the L2 strain. We also identified 4 genetic L2b ompA variants.

  15. Elastic scattering of 8He on 4He and 4 n system

    NASA Astrophysics Data System (ADS)

    Wolski, R.; Sidorchuk, S. I.; Ter-Akopian, G. M.; Fomichev, A. S.; Rodin, A. M.; Stepantsov, S. V.; Mittig, W.; Roussel-Chomaz, P.; Savajols, H.; Alamanos, N.; Auger, F.; Lapoux, V.; Raabe, R.; Tchuvil'sky, Yu. M.; Rusek, K.

    2003-07-01

    Elastic scattering of a 26A MeV beam of 8He on a gaseous helium target has been studied. In spite of efforts made for the observation of backward angle enhancement only upper limits could be obtained for the elastic scattering cross section at backward angles. The angular distribution of 8He nuclei scattered to CM 20°-80° was was analyzed in terms of a phenomenological Optical Model. Possible contributions from transfer reactions were estimated. The DWBA calculations indicate that the two step 2n transfer is more important than the one step 4n transfer. The transfer reaction d( 8He, 6Li)4n is discussed in terms of possible tests of a four-neutron system.

  16. Did case-based payment influence surgical readmission rates in France? A retrospective study

    PubMed Central

    Vuagnat, Albert; Yilmaz, Engin; Roussot, Adrien; Rodwin, Victor; Gadreau, Maryse; Bernard, Alain; Creuzot-Garcher, Catherine; Quantin, Catherine

    2018-01-01

    Objectives To determine whether implementation of a case-based payment system changed all-cause readmission rates in the 30 days following discharge after surgery, we analysed all surgical procedures performed in all hospitals in France before (2002–2004), during (2005–2008) and after (2009–2012) its implementation. Setting Our study is based on claims data for all surgical procedures performed in all acute care hospitals with >300 surgical admissions per year (740 hospitals) in France over 11 years (2002–2012; n=51.6 million admissions). Interventions We analysed all-cause 30-day readmission rates after surgery using a logistic regression model and an interrupted time series analysis. Results The overall 30-day all-cause readmission rate following discharge after surgery increased from 8.8% to 10.0% (P<0.001) for the public sector and from 5.9% to 8.6% (P<0.001) for the private sector. Interrupted time series models revealed a significant linear increase in readmission rates over the study period in all types of hospitals. However, the implementation of case-based payment was only associated with a significant increase in rehospitalisation rates for private hospitals (P<0.001). Conclusion In France, the increase in the readmission rate appears to be relatively steady in both the private and public sector but appears not to have been affected by the introduction of a case-based payment system after accounting for changes in care practices in the public sector. PMID:29391376

  17. Construction of all N=4 conformal supergravities.

    PubMed

    Butter, Daniel; Ciceri, Franz; de Wit, Bernard; Sahoo, Bindusar

    2017-02-24

    All N=4 conformal supergravities in four space-time dimensions are constructed. These are the only N=4 supergravity theories whose actions are invariant under off-shell supersymmetry. They are encoded in terms of a holomorphic function that is homogeneous of zeroth degree in scalar fields that parametrize an SU(1,1)/U(1) coset space. When this function equals a constant the Lagrangian is invariant under continuous SU(1,1) transformations. The construction of these higher-derivative invariants also opens the door to various applications for nonconformal theories.

  18. Calcium requirements from dairy foods in France can be met at low energy and monetary cost.

    PubMed

    Drewnowski, Adam; Tang, Wesley; Brazeilles, Rémi

    2015-12-14

    Inadequate Ca intakes are a concern for global public health. In France, most dietary Ca is provided by dairy products: milks, fermented milks (mostly yogurts), dairy desserts and cheeses. The present dairy database (n 837) included milks (n 101), fermented milks, yogurts and other fresh dairy products (n 326), desserts (n 162) and a wide variety of cheeses (n 248). Energy and nutrient values were obtained from industry sources and the French national nutrient composition database. Retail prices were from Paris supermarkets. Products in each group were aggregated into twenty-one categories using clustering analyses. The costs in energy (kJ (kcal)), euros (€), and in SFA, added sugar and Na (defined here as nutrients to LIMit) associated with providing 120 mg of Ca (equivalent to 15 % daily value (15 % DV)) were calculated for each product group and category. The milk group supplied Ca at the lowest energy, monetary and LIM cost. Fresh plain and 'light' yogurts and fermented milks were next, followed by sweetened yogurts and flavoured milks. Light dairy desserts provided Ca with relatively few energy but were more expensive. Cheeses were a heterogeneous group. Hard cheeses (Comté) provided the most Ca per serving. Semi-hard cheeses (Camembert) and cream and blue cheeses (Roquefort) provided Ca at a cost comparable with sweetened yogurts and flavoured milks. Double cream, soft and goat cheeses were not optimal Ca sources. New value metrics can help identify affordable dairy foods that provide Ca without excessive energy or nutrients to limit. These conditions were satisfied by a wide variety of dairy products in France.

  19. Photocatalytic decomposition of N2O over TiO2/g-C3N4 photocatalysts heterojunction

    NASA Astrophysics Data System (ADS)

    Kočí, K.; Reli, M.; Troppová, I.; Šihor, M.; Kupková, J.; Kustrowski, P.; Praus, P.

    2017-02-01

    TiO2/g-C3N4 photocatalysts with the various TiO2/g-C3N4 weight ratios from 1:2 to 1:6 were fabricated by mechanical mixing in water suspension followed by calcination. Pure TiO2 was prepared by thermal hydrolysis and pure g-C3N4 was prepared from commercial melamine by thermal annealing at 620 °C. All the nanocomposites were characterized by X-ray powder diffraction, UV-vis diffuse reflectance spectroscopy, Raman spectroscopy, infrared spectroscopy, scanning electron microscopy, transmission electron microscopy, photoelectrochemical measurements and nitrogen physisorption. The prepared mixtures along with pure TiO2 and g-C3N4 were tested for the photocatalytic decomposition of nitrous oxide under UVC (λ = 254 nm), UVA (λ = 365 nm) and Vis (λ > 400 nm) irradiation. The TiO2/g-C3N4 nanocomposites showed moderate improvement compared to pure g-C3N4 but pure TiO2 proved to be a better photocatalyst under UVC irradiation. However, under UVA irradiation conditions, the photocatalytic activity of TiO2/g-C3N4 (1:2) nanocomposite exhibited an increase compared to pure TiO2. Nevertheless, further increase of g-C3N4 amount leads/led to a decrease in reactivity. These results are suggesting the nanocomposite with the optimal weight ratio of TiO2 and g-C3N4 have shifted absorption edge energy towards longer wavelengths and decreased the recombination rate of charge carriers compared to pure g-C3N4. This is probably due to the generation of heterojunction on the TiO2/g-C3N4 interface.

  20. [The Lebanese in France: population trends and characteristics].

    PubMed

    Abdulkarim, A

    1993-01-01

    Demographic characteristics, population trends, and the spatial distribution of Lebanese migrants to France are examined and compared with those of migrants from other countries. The focus is on the decision to migrate and its effect on life in France. The author concludes that Lebanese migration is primarily labor migration, even during times of political upheaval and war, and that this motivation contributes to the assimilation of the Lebanese into the middle and upper socioeconomic classes. (SUMMARY IN ENG AND SPA)