75 FR 10658 - Airworthiness Directives; The Boeing Company Model 737-100, -200, -200C, -300, -400, and -500...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-09

... Airworthiness Directives; The Boeing Company Model 737-100, -200, -200C, -300, -400, and -500 Series Airplanes..., -200, -200C, -300, -400, and - 500 series airplanes. That AD currently requires a one-time inspection... 16211, March 31, 2006). The existing AD applies to all Model 737-100, -200, -200C, -300, -400, and -500...

miR-200b and miR-200c as prognostic factors and mediators of gastric cancer cell progression.

PubMed

Tang, Hailin; Deng, Min; Tang, Yunyun; Xie, Xinhua; Guo, Jiaoli; Kong, Yanan; Ye, Feng; Su, Qi; Xie, Xiaoming

2013-10-15

The purpose of this study was to investigate the clinicopathologic significance and potential role of miR-200b and miR-200c in the development and progression of gastric cancer. We examined miR-200b and miR-200c expression in 36 paired normal and stomach tumor specimens, as well as gastric cancer cell lines, by quantitative real-time PCR. In addition, miR-200b and miR-200c were detected by ISH using gastric cancer tissue microarrays, and the association between miR-200b and miR-200c levels and clinicopathologic factors and prognosis were analyzed. A luciferase assay was conducted for target evaluation. The functional effects of miR-200b and miR-200c on gastric cancer cells were validated by a cell proliferation assay and cell invasion and migration assays. miR-200b and miR-200c were downregulated in the gastric cancer specimens and cell lines tested. miR-200b and miR-200c levels were significantly correlated with the clinical stage, T stage, lymph node metastasis, and survival of patients. Ectopic expression of miR-200b and miR-200c impaired cell growth and invasion. In addition, when overexpressed, miR-200b and miR-200c commonly directly targeted DNMT3A, DNMT3B, and SP1 (a transactivator of the DNMT1 gene), which resulted in marked reduction of the expression of DNA methyltransferases DNMT1, DNMT3A, and DNMT3B at the protein level. This effect, in turn, led to a decrease in global DNA methylation and reexpression of p16, RASS1A1, and E-cadherin via promoter DNA hypomethylation. Our findings suggest that miR-200b and miR-200c, as valuable markers of gastric cancer prognosis, may be a promising approach to human gastric cancer treatment. ©2013 AACR.

CD200 Positive Human Mesenchymal Stem Cells Suppress TNF-Alpha Secretion from CD200 Receptor Positive Macrophage-Like Cells

PubMed Central

Pietilä, Mika; Lehtonen, Siri; Tuovinen, Elina; Lähteenmäki, Kaarina; Laitinen, Saara; Leskelä, Hannu-Ville; Nätynki, Antti; Pesälä, Juha; Nordström, Katrina; Lehenkari, Petri

2012-01-01

Human mesenchymal stem cells (hMSCs) display immunosuppressive properties in vitro and the potential has also been transferred successfully to clinical trials for treatment of autoimmune diseases. OX-2 (CD200), a member of the immunoglobulin superfamily, is widely expressed in several tissues and has recently been found from hMSCs. The CD200 receptor (CD200R) occurs only in myeloid-lineage cells. The CD200-CD200R is involved in down-regulation of several immune cells, especially macrophages. The present study on 20 hMSC lines shows that the CD200 expression pattern varied from high (CD200Hi) to medium (CD200Me) and low (CD200Lo) in bone marrow-derived mesenchymal stem cell (BMMSC) lines, whereas umbilical cord blood derived mesenchymal stem cells (UCBMSCs) were constantly negative for CD200. The role of the CD200-CD200R axis in BMMSCs mediated immunosuppression was studied using THP-1 human macrophages. Interestingly, hMSCs showed greater inhibition of TNF-α secretion in co-cultures with IFN-γ primed THP-1 macrophages when compared to LPS activated cells. The ability of CD200Hi BMMSCs to suppress TNF-α secretion from IFN-γ stimulated THP-1 macrophages was significantly greater when compared to CD200Lo whereas UCBMSCs did not significantly reduce TNF-α secretion. The interference of CD200 binding to the CD200R by anti-CD200 antibody weakened the capability of BMMSCs to inhibit TNF-α secretion from IFN-γ activated THP-1 macrophages. This study clearly demonstrated that the efficiency of BMMSCs to suppress TNF-α secretion of THP-1 macrophages was dependent on the type of stimulus. Moreover, the CD200-CD200r axis could have a previously unidentified role in the BMMSC mediated immunosuppression. PMID:22363701

77 FR 46343 - Airworthiness Directives; The Boeing Company Airplanes

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-03

... certain The Boeing Company Model 747-100, 747-100B, 747-100B SUD, 747-200B, 747-200C, 747-200F, 747-300, 747-400, 747-400D, 747-400F, 747SR, and 747SP series airplanes; and certain Model 757-200, -200PF, and... applies to The Boeing Company Model 747-100, 747-100B, 747-100B SUD, 747-200B, 747-200C, 747-200F, 747-300...

Overexpression of the miR-141/200c cluster promotes the migratory and invasive ability of triple-negative breast cancer cells through the activation of the FAK and PI3K/AKT signaling pathways by secreting VEGF-A.

PubMed

Choi, Sul Ki; Kim, Hoe Suk; Jin, Tiefeng; Hwang, Eun Hye; Jung, Minji; Moon, Woo Kyung

2016-08-02

The role of microRNA-200 (miR-200) family members in the migration and invasion of breast cancer is controversial. This study investigated the mechanisms by which the miR-200 family members modulated the migratory and invasive abilities of an aggressive triple-negative breast cancer (TNBC) cell line, MDA-MB-231. The miR-200 family (miR-200b/200a/429 and miR-141/200c clusters) and green fluorescence protein (GFP) were transduced into MDA-MB-231 cells using a lentiviral system. Stable cells highly expressing the miR-200 family and GFP were isolated by puromycin selection and fluorescence-activated cell sorting. Gene expression was evaluated using real-time polymerase chain reaction (PCR) and reverse transcriptase-PCR (RT-PCR). The migratory and invasive abilities were assessed using trans-well and wound-healing assays. The secreted cytokines and growth factors in cultured media were quantified using a Bio-Plex200 multiplex array system. Western blot assays and immunofluorescence staining were conducted to investigate miR-200 family-regulated signaling pathways. The entire dataset obtained in this study was statistically evaluated using a one-way ANOVA followed by a t-test. The stable overexpression of the miR-200b/200a/429 or miR-141/200c cluster suppressed cell growth and significantly increased migration and invasion of MDA-MB-231 cells. miR-141/200c overexpression was more effective in decreasing cell growth and promoting migration and invasion of MDA-MB-231 cells than was miR-200b/200a/429 overexpression. In addition, the overexpression of the miR-200b/200a/429 or miR-141/200c cluster led to an increase in the phosphorylation of focal adhesion kinase (FAK) and protein kinase B (AKT). Chemical inhibitors of FAK and phosphatidylinositol-4,5-bisphosphate 3-kinase (PI3K)/AKT suppressed the migration and invasion of MDA-MB-231 cells that was enhanced by the overexpression of the miR-200b/200a/429 or miR-141/200c cluster. Compared to the miR-200b/200a/429 cluster-transduced MDA-MB-231 cells, the miR-141/200c cluster-transduced MDA-MB-231 cells exhibited a significant increase in vascular endothelial growth factor (VEGF)-A secretion and integrin-alphaV (integrin-αV) expression. Treatment with an anti-VEGF-A-neutralizing antibody inhibited the increase in migration and invasion in both the miR-200b/200a/429- and miR-141/200c-transduced MDA-MB-231 cells but significantly reduced the phosphorylation of FAK and AKT in only the miR-141/200c cluster-transduced MDA-MB-231 cells. Taken together, our data demonstrate a mechanism in which the miR-141/200c cluster, through FAK- and PI3K/AKT-mediated signaling by means of increased VEGF-A secretion, promotes the migratory and invasive abilities of MDA-MB-231 cells.

Impact of CD200-Fc on dendritic cells in lupus-prone NZB/WF1 mice

DOE PAGES

Yin, Yufeng; Zhao, Lidan; Zhang, Fengchun; ...

2016-08-22

Abnormal expression of CD200/CD200R1 may contribute to the immunologic abnormalities in patients with systemic lupus erythematosus (SLE). This study aimed to assess the function of CD200/CD200R1and impact of CD200-Fc on dendritic cells in lupus-prone NZB/WF1 mice. Female NZB/WF1 mice were treated with CD200-Fc or control for 4 weeks. Plasma samples were collected to measure autoantibody levels. The expression levels of CD200/CD200R1 in peripheral blood mononuclear cells (PBMCs) and splenocytes were examined. The percentage of CD200/CD200R1-positive cells in splenocytes from NZB/WF1 mice was lower than that of C57BL/6 mice (p<0.05). The plasma level of anti-dsDNA was significantly higher in NZB/WF1 micemore » than C57BL/6 mice (p<0.001). However, the anti-dsDNA levels decreased (p=0.047) after CD200-Fc treatment. Finally, CD200-Fc reduced the levels of IL-6 (p=0.017) and IL-10 (p=0.03) in the dendritic cell culture supernatant. This study suggests that the immunosuppressive CD200/CD200R1 signaling pathway might be involved in the immunopathology of NZB/WF1 mice; the present results merit further exploration of agents that can modulate the CD200/CD200FR1 pathway as a therapy for human lupus.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yin, Yufeng; Zhao, Lidan; Zhang, Fengchun

Abnormal expression of CD200/CD200R1 may contribute to the immunologic abnormalities in patients with systemic lupus erythematosus (SLE). This study aimed to assess the function of CD200/CD200R1and impact of CD200-Fc on dendritic cells in lupus-prone NZB/WF1 mice. Female NZB/WF1 mice were treated with CD200-Fc or control for 4 weeks. Plasma samples were collected to measure autoantibody levels. The expression levels of CD200/CD200R1 in peripheral blood mononuclear cells (PBMCs) and splenocytes were examined. The percentage of CD200/CD200R1-positive cells in splenocytes from NZB/WF1 mice was lower than that of C57BL/6 mice (p<0.05). The plasma level of anti-dsDNA was significantly higher in NZB/WF1 micemore » than C57BL/6 mice (p<0.001). However, the anti-dsDNA levels decreased (p=0.047) after CD200-Fc treatment. Finally, CD200-Fc reduced the levels of IL-6 (p=0.017) and IL-10 (p=0.03) in the dendritic cell culture supernatant. This study suggests that the immunosuppressive CD200/CD200R1 signaling pathway might be involved in the immunopathology of NZB/WF1 mice; the present results merit further exploration of agents that can modulate the CD200/CD200FR1 pathway as a therapy for human lupus.« less

Nanofoil Heating Elements for Thermal Batteries

DTIC Science & Technology

2008-12-01

microtherm discs are used to limit the axial heat transfer from the stack. 0 100 200 300 400 500 600 700 800 900 1000 1100 -5 5 15 25 35 45 55 65...Time, t / s T em pe ra tu re , θ / °C 3-2-3, 200 lb, no microtherm 3-2-3, 200 lb, microtherm 2-2-2, 200 lb, microtherm 2-3-2, 200 lb, microtherm 2...4-2, 200 lb, microtherm 2-4-2, 100 lb, microtherm 1-4-1, 200 lb, microtherm 1-2-1, 200 lb, microtherm 3-3-3, 200 lb, microtherm

A Critical Role for CD200R Signaling in Limiting the Growth and Metastasis of CD200+ Melanoma.

PubMed

Liu, Jin-Qing; Talebian, Fatemeh; Wu, Lisha; Liu, Zhihao; Li, Ming-Song; Wu, Laichu; Zhu, Jianmin; Markowitz, Joseph; Carson, William E; Basu, Sujit; Bai, Xue-Feng

2016-08-15

CD200 is a cell surface glycoprotein that functions through engaging CD200R on cells of the myeloid lineage and inhibits their functions. Expression of CD200 was implicated in a variety of human cancer cells, including melanoma cells; however, its roles in tumor growth and immunity are not clearly understood. In this study, we used CD200R-deficient mice and the B16 tumor model to evaluate this issue. We found that CD200R-deficient mice exhibited accelerated growth of CD200(+), but not CD200(-), B16 tumors. Strikingly, CD200R-deficient mice receiving CD200(+) B16 cells i.v. exhibited massive tumor growth in multiple organs, including liver, lung, kidney, and peritoneal cavity, whereas the growth of the same tumors in wild-type mice was limited. CD200(+) tumors grown in CD200R-deficient mice contained higher numbers of CD11b(+)Ly6C(+) myeloid cells, exhibited increased expression of VEGF and HIF1α genes with increased angiogenesis, and showed significantly reduced infiltration of CD4(+) and CD8(+) T cells, presumably as the result of reduced expression of T cell chemokines, such as CXCL9 and CXCL16. The liver from CD200R-deficient mice, under metastatic growth of CD200(+) tumors, contained significantly increased numbers of CD11b(+)Gr1(-) myeloid cells and Foxp3(+) regulatory T cells and reduced numbers of NK cells. Liver T cells also had a reduced capacity to produce IFN-γ or TNF-α. Taken together, we revealed a critical role for CD200R signaling in limiting the growth and metastasis of CD200(+) tumors. Thus, targeting CD200R signaling may potentially interfere with the metastatic growth of CD200(+) tumors, like melanoma. Copyright © 2016 by The American Association of Immunologists, Inc.

34 CFR 200.104-200.109 - [Reserved

Code of Federal Regulations, 2012 CFR

2012-07-01

... 34 Education 1 2012-07-01 2012-07-01 false [Reserved] 200.104-200.109 Section 200.104-200.109 Education Regulations of the Offices of the Department of Education OFFICE OF ELEMENTARY AND SECONDARY EDUCATION, DEPARTMENT OF EDUCATION TITLE I-IMPROVING THE ACADEMIC ACHIEVEMENT OF THE DISADVANTAGED General...

34 CFR 200.101-200.102 - [Reserved

Code of Federal Regulations, 2012 CFR

2012-07-01

... 34 Education 1 2012-07-01 2012-07-01 false [Reserved] 200.101-200.102 Section 200.101-200.102 Education Regulations of the Offices of the Department of Education OFFICE OF ELEMENTARY AND SECONDARY EDUCATION, DEPARTMENT OF EDUCATION TITLE I-IMPROVING THE ACADEMIC ACHIEVEMENT OF THE DISADVANTAGED General...

miR-200a controls hepatic stellate cell activation and fibrosis via SIRT1/Notch1 signal pathway.

PubMed

Yang, Jing-Jing; Tao, Hui; Liu, Li-Ping; Hu, Wei; Deng, Zi-Yu; Li, Jun

2017-04-01

miR-200a has been established as a key regulator of HSC activation processes in liver fibrosis. Epigenetic silencing of miR-200a contributing to SIRT1 over-expression has been discussed in breast cancer; however, whether miR-200a controls SIRT1 gene expression in hepatic fibrosis is still unknown. We analyzed miR-200a regulation of SIRT1 expression in CCl 4 -induced liver fibrosis and TGF-β1-mediated activation of HSC. miR-200a, SIRT1, α-SMA, Col1A1, Notch1 and NICD expression were estimated by Western blotting, qRT-PCR and Immunohistochemistry. HSCs were transfected with miR-200a mimic, miR-200a inhibitor and SIRT1-RNAi. Luciferase reporter assays further confirmed the interaction between miR-200a and the SIRT1 mRNA 3'-UTR. Cell proliferation ability was assessed by MTT and cell cycle. We found that treatment activated HSC with miR-200a mimics, restored miR-200a expression and reduced SIRT1 levels. Conversely, treatment activated HSC with miR-200a inhibitors, decreased miR-200a expression and up-regulated SIRT1 levels. Restoration of miR-200a or the knockdown of SIRT1 prevented HSC activation and proliferation. We have established the SIRT1 transcript as subject to regulation by miR-200a, through miR-200a targeting of SIRT1 3'-UTR. Finally, HSC transfected with SIRT1-siRNA increased the levels of Notch1 protein and mRNA expression. Our study demonstrated that miR-200a regulates SIRT1/Notch1 expression during HSC activation and fibrosis.

Cell membrane-bound CD200 signals both via an extracellular domain and following nuclear translocation of a cytoplasmic fragment.

PubMed

Chen, Zhiqi; Kapus, Andras; Khatri, Ismat; Kos, Olha; Zhu, Fang; Gorczynski, Reginald M

2018-06-01

In previous studies we had reported that the immunosuppressive cell membrane bound molecule CD200 is released from the cell following cleavage by matrix metalloproteases, with the released soluble CD200 acting as an immunosuppressant following binding to, and signaling through, its cognate receptor CD200R expressed on target cells. We now show that although the intracellular cytoplasmic tail (CD200 C-tail ) of CD200 has no consensus sites for adapter molecules which might signal the CD200 + cell directly, cleavage of the CD200 C-tail from the membrane region of CD200 by a consensus γ-secretase, leads to nuclear translocation and DNA binding (identified by chromatin immunoprecipitation followed by sequencing, Chip-sequencing) of the CD200 C-tail . Subsequently there occurs an altered expression of a limited number of genes, many of which are transcription factors (TFs) known to be associated with regulation of cell proliferation. Altered expression of these TFs was also prominent following transfection of CD200 + B cell lines and fresh patient CLL cells with a vector construct containing the CD200 C-tail . Artificial transfection of non CD200 + Hek293 cells with this CD200 C-tail construct resulted in altered expression of most of these same genes. Introduction of a siRNA for one of these TFs, POTEA, reversed CD200 C-tail regulation of altered cell proliferation. Copyright © 2018 Elsevier Ltd. All rights reserved.

CD200 modulates spinal cord injury neuroinflammation and outcome through CD200R1.

PubMed

Lago, Natalia; Pannunzio, Bruno; Amo-Aparicio, Jesús; López-Vales, Rubèn; Peluffo, Hugo

2018-06-02

The interaction between CD200 and its receptor CD200R1 is among the central regulators of microglia and macrophage phenotype. However, it remains to be established whether, in the context of a traumatic CNS injury, CD200R1 act as a negative regulator of these particular innate immune cells, and if the exogenous delivery of CD200 may ameliorate neurological deficits. In the present study, we first evaluated whether preventing the local interaction between the pair CD200-CD200R1, by using a selective blocking antibody against CD200R1, has a role on functional and inflammatory outcome after contusion-induced spinal cord injury (SCI) in mice. The injection of the αCD200R1, but not control IgG1, into the lesioned spinal cord immediately after the SCI worsened locomotor performance and exacerbated neuronal loss and demyelination. At the neuroimmunological level, we observed that microglial cells and macrophages showed increased levels of iNOS and Ly6C upon CD200R1 blockade, indicating that the disruption of CD200R1 drove these cells towards a more pro-inflammatory phenotype. Moreover, although CD200R1 blockade had no effect in the initial infiltration of neutrophils into the lesioned spinal cord, it significantly impaired their clearance, which is a key sign of excessive inflammation. Interestingly, intraparenchymal injection of recombinant CD200-His immediately after the injury induced neuroprotection and robust and long-lasting locomotor recovery. In conclusion, this study reveals that interaction of CD200-CD200R1 plays a crucial role in limiting inflammation and lesion progression after SCI, and that boosting the stimulation of this pathway may constitute a new therapeutic approach. Copyright © 2018. Published by Elsevier Inc.

21 CFR 200.200 - Prescription drugs; reminder advertisements and reminder labeling to provide price information to...

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Prescription drugs; reminder advertisements and reminder labeling to provide price information to consumers. 200.200 Section 200.200 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL GENERAL Prescription Drug Consumer Price Listing §...

75 FR 38394 - Airworthiness Directives; The Boeing Company Model 747-100, -200B, and -200F Series Airplanes

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-02

... Airworthiness Directives; The Boeing Company Model 747-100, - 200B, and -200F Series Airplanes AGENCY: Federal... inconsistent with the terminology used in the structural repair manual and Boeing Alert Service Bulletin 747... The Boeing Company Model 747-100, 747- 200B, and 747-200F series airplanes, certificated in any...

Tumor Expression of CD200 Inhibits IL-10 Production by Tumor-Associated Myeloid Cells and Prevents Tumor Immune Evasion of CTL Therapy

PubMed Central

Wang, Lixin; Liu, Jin-Qing; Talebian, Fatemeh; El-Omrani, Hani Y.; Khattabi, Mazin; Yu, Li; Bai, Xue-Feng

2010-01-01

CD200 is a cell-surface glycoprotein that functions through interaction with the CD200 receptor (CD200R) on myeloid lineage cells to regulate myeloid cell functions. Expression of CD200 has been implicated in multiple types of human cancer, however the impact of tumor expression of CD200 on tumor immunity remains poorly understood. To evaluate this issue, we generated CD200-positive mouse plasmacytoma J558 and mastocytoma P815 cells. We found that established CD200-positive tumors were often completely rejected by adoptively transferred CTL without tumor recurrence; in contrast, CD200-negative tumors were initially rejected by adoptively transferred CTL but the majority of tumors recurred. Tumor expression of CD200 significantly inhibited suppressive activity and IL-10 production by tumor-associated myeloid cells (TAMC), and as a result, more CTL accumulated in the tumor and exhibited a greater capacity to produce IFN-γ in CD200-positive tumors than in CD200-negative tumors. Neutralization of IL-10 significantly inhibited the suppressor activity of TAMC, and IL-10-deficiency allowed TAMC to kill cancer cells and their antigenic variants, which prevented tumor recurrence during CTL therapy. Thus, tumor expression of CD200 prevents tumor recurrence via inhibiting IL-10 production by TAMC. PMID:20662098

40 CFR 180.123 - Inorganic bromide residues resulting from fumigation with methyl bromide; tolerances for residues.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Cantaloupe, postharvest 20.0 None Carrot, roots, postharvest 30.0 None Cashew, postharvest 200.0 None Cherry..., postharvest 20.0 None Nut, brazil, postharvest 200.0 None Nut, hickory, postharvest 200.0 None Nut, macadamia...

40 CFR 180.123 - Inorganic bromide residues resulting from fumigation with methyl bromide; tolerances for residues.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Cantaloupe, postharvest 20.0 None Carrot, roots, postharvest 30.0 None Cashew, postharvest 200.0 None Cherry..., postharvest 20.0 None Nut, brazil, postharvest 200.0 None Nut, hickory, postharvest 200.0 None Nut, macadamia...

40 CFR 180.123 - Inorganic bromide residues resulting from fumigation with methyl bromide; tolerances for residues.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Cantaloupe, postharvest 20.0 None Carrot, roots, postharvest 30.0 None Cashew, postharvest 200.0 None Cherry..., postharvest 20.0 None Nut, brazil, postharvest 200.0 None Nut, hickory, postharvest 200.0 None Nut, macadamia...

MicroRNA-200a/200b Modulate High Glucose-Induced Endothelial Inflammation by Targeting O-linked N-Acetylglucosamine Transferase Expression.

PubMed

Lo, Wan-Yu; Yang, Wen-Kai; Peng, Ching-Tien; Pai, Wan-Yu; Wang, Huang-Joe

2018-01-01

Background and Aims: Increased O -linked N -acetylglucosamine ( O -GlcNAc) modification of proteins by O -GlcNAc transferase (OGT) is associated with diabetic complications. Furthermore, oxidative stress promotes endothelial inflammation during diabetes. A previous study reported that microRNA-200 (miR-200) family members are sensitive to oxidative stress. In this study, we examined whether miR-200a and miR-200b regulate high-glucose (HG)-induced OGT expression in human aortic endothelial cells (HAECs) and whether miRNA-200a/200b downregulate OGT expression to control HG-induced endothelial inflammation. Methods: HAECs were stimulated with high glucose (25 mM) for 12 and 24 h. Real-time polymerase chain reaction (PCR), western blotting, THP-1 adhesion assay, bioinformatics predication, transfection of miR-200a/200b mimic or inhibitor, luciferase reporter assay, and transfection of siRNA OGT were performed. The aortic endothelium of db/db diabetic mice was evaluated by immunohistochemistry staining. Results: HG upregulated OGT mRNA and protein expression and protein O -GlcNAcylation levels (RL2 antibody) in HAECs, and showed increased intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion molecule 1 (VCAM-1), and E-selectin gene expression; ICAM-1 expression; and THP-1 adhesion. Bioinformatics analysis revealed homologous sequences between members of the miR-200 family and the 3'-untranslated region (3'-UTR) of OGT mRNA, and real-time PCR analysis confirmed that members of miR-200 family were significantly decreased in HG-stimulated HAECs. This suggests the presence of an impaired feedback restraint on HG-induced endothelial protein O -GlcNAcylation levels because of OGT upregulation. A luciferase reporter assay demonstrated that miR-200a/200b mimics bind to the 3'-UTR of OGT mRNA. Transfection with miR-200a/200b mimics significantly inhibited HG-induced OGT mRNA expression, OGT protein expression; protein O -GlcNAcylation levels; ICAM-1, VCAM-1, and E-selectin gene expression; ICAM-1 expression; and THP-1 adhesion. Additionally, siRNA-mediated OGT depletion reduced HG-induced protein O -GlcNAcylation; ICAM-1, VCAM-1, and E-selectin gene expression; ICAM-1 expression; and THP-1 adhesion, confirming that HG-induced endothelial inflammation is partially mediated via OGT-induced protein O -GlcNAcylation. These results were validated in vivo : tail-vein injection of miR-200a/200b mimics downregulated endothelial OGT and ICAM-1 expression in db/db mice. Conclusion: miR-200a/200b are involved in modulating HG-induced endothelial inflammation by regulating OGT-mediated protein O -GlcNAcylation, suggesting the therapeutic role of miR-200a/200b on vascular complications in diabetes.

CD200 Receptor Controls Sex-Specific TLR7 Responses to Viral Infection

PubMed Central

Raaben, Matthijs; Grinwis, Guy C. M.; Coenjaerts, Frank E.; Ressing, Maaike E.; Rottier, Peter J. M.; de Haan, Cornelis A. M.; Meyaard, Linde

2012-01-01

Immunological checkpoints, such as the inhibitory CD200 receptor (CD200R), play a dual role in balancing the immune system during microbial infection. On the one hand these inhibitory signals prevent excessive immune mediated pathology but on the other hand they may impair clearance of the pathogen. We studied the influence of the inhibitory CD200-CD200R axis on clearance and pathology in two different virus infection models. We find that lack of CD200R signaling strongly enhances type I interferon (IFN) production and viral clearance and improves the outcome of mouse hepatitis corona virus (MHV) infection, particularly in female mice. MHV clearance is known to be dependent on Toll like receptor 7 (TLR7)-mediated type I IFN production and sex differences in TLR7 responses previously have been reported for humans. We therefore hypothesize that CD200R ligation suppresses TLR7 responses and that release of this inhibition enlarges sex differences in TLR7 signaling. This hypothesis is supported by our findings that in vivo administration of synthetic TLR7 ligand leads to enhanced type I IFN production, particularly in female Cd200−/− mice and that CD200R ligation inhibits TLR7 signaling in vitro. In influenza A virus infection we show that viral clearance is determined by sex but not by CD200R signaling. However, absence of CD200R in influenza A virus infection results in enhanced lung neutrophil influx and pathology in females. Thus, CD200-CD200R and sex are host factors that together determine the outcome of viral infection. Our data predict a sex bias in both beneficial and pathological immune responses to virus infection upon therapeutic targeting of CD200-CD200R. PMID:22615569

2 CFR 200.86 - Recipient.

Code of Federal Regulations, 2014 CFR

2014-01-01

... AWARDS Acronyms and Definitions Acronyms § 200.86 Recipient. Recipient means a non-Federal entity that... program. The term recipient does not include subrecipients. See also § 200.69 Non-Federal entity. ... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Recipient. 200.86 Section 200.86 Grants and...

36 CFR 200.5 - Indexes.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Indexes. 200.5 Section 200.5..., AND PROCEDURES Functions and Procedures § 200.5 Indexes. Publication of the indexes described in § 200.... However, copies of the indexes are available for public review in the Forest Service headquarters office...

Role for DNA methylation in the regulation of miR-200c and miR-141 expression in normal and cancer cells

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vrba, Lukas; Jensen, Taylor J.; Garbe, James C.

2009-12-23

BACKGROUND: The microRNA-200 family participates in the maintenance of an epithelial phenotype and loss of its expression can result in epithelial to mesenchymal transition (EMT). Furthermore, the loss of expression of miR-200 family members is linked to an aggressive cancer phenotype. Regulation of the miR-200 family expression in normal and cancer cells is not fully understood. METHODOLOGY/ PRINCIPAL FINDINGS: Epigenetic mechanisms participate in the control of miR-200c and miR-141 expression in both normal and cancer cells. A CpG island near the predicted mir-200c/mir-141 transcription start site shows a striking correlation between miR-200c and miR-141 expression and DNA methylation in bothmore » normal and cancer cells, as determined by MassARRAY technology. The CpG island is unmethylated in human miR-200/miR-141 expressing epithelial cells and in miR-200c/miR-141 positive tumor cells. The CpG island is heavily methylated in human miR-200c/miR-141 negative fibroblasts and miR-200c/miR-141 negative tumor cells. Mouse cells show a similar inverse correlation between DNA methylation and miR-200c expression. Enrichment of permissive histone modifications, H3 acetylation and H3K4 trimethylation, is seen in normal miR-200c/miR-141-positive epithelial cells, as determined by chromatin immunoprecipitation coupled to real-time PCR. In contrast, repressive H3K9 dimethylation marks are present in normal miR-200c/miR-141-negative fibroblasts and miR-200c/miR-141 negative cancer cells and the permissive histone modifications are absent. The epigenetic modifier drug, 5-aza-2'-deoxycytidine, reactivates miR-200c/miR-141 expression showing that epigenetic mechanisms play a functional role in their transcriptional control. CONCLUSIONS/ SIGNIFICANCE: We report that DNA methylation plays a role in the normal cell type-specific expression of miR-200c and miR-141 and this role appears evolutionarily conserved, since similar results were obtained in mouse. Aberrant DNA methylation of the miR-200c/141 CpG island is closely linked to their inappropriate silencing in cancer cells. Since the miR-200c cluster plays a significant role in EMT, our results suggest an important role for DNA methylation in the control of phenotypic conversions in normal cells.« less

34 CFR 200.32 - Identification for school improvement.

Code of Federal Regulations, 2012 CFR

2012-07-01

... defined under §§ 200.13 through 200.20. (ii) In identifying schools for improvement, an LEA— (A) May base... LEA must, in accordance with § 200.44, provide public school choice to all students in the school. (c... LEA must— (i) In accordance with § 200.44, provide public school choice to all students in the school...

34 CFR 200.32 - Identification for school improvement.

Code of Federal Regulations, 2014 CFR

2014-07-01

... defined under §§ 200.13 through 200.20. (ii) In identifying schools for improvement, an LEA— (A) May base... LEA must, in accordance with § 200.44, provide public school choice to all students in the school. (c... LEA must— (i) In accordance with § 200.44, provide public school choice to all students in the school...

34 CFR 200.32 - Identification for school improvement.

Code of Federal Regulations, 2013 CFR

2013-07-01

... defined under §§ 200.13 through 200.20. (ii) In identifying schools for improvement, an LEA— (A) May base... LEA must, in accordance with § 200.44, provide public school choice to all students in the school. (c... LEA must— (i) In accordance with § 200.44, provide public school choice to all students in the school...

MiR-200c Inhibits the Tumor Progression of Glioma via Targeting Moesin

PubMed Central

Qin, Yuanyuan; Chen, Weilong; Liu, Bingjie; Zhou, Lei; Deng, Lu; Niu, Wanxiang; Bao, Dejun; Cheng, Chuandong; Li, Dongxue; Liu, Suling; Niu, Chaoshi

2017-01-01

We attempt to demonstrate the regulatory role of miR-200c in glioma progression and its mechanisms behind. Here, we show that miR-200c expression was significantly reduced in the glioma tissues compared to paratumor tissues, especially in malignant glioma. Exogenous overexpression of miR-200c inhibited the proliferation and invasion of glioma cells. In addition, the in vivo mouse xenograft model showed that miR-200c inhibited glioma growth and liver metastasis, which is mainly regulated by targeting moesin (MSN). We demonstrated that the expression of MSN in glioma specimens were negatively correlated with miR-200c expression, and MSN overexpression rescued the phenotype about cell proliferation and invasion induced by miR-200c. Moreover, knockdown of MSN was able to mimic the effects induced by miR-200c in glioma cells. These results indicate that miR-200c plays an important role in the regulation of glioma through targeting MSN. PMID:28529643

40 CFR 243.200 - Storage.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Storage. 243.200 Section 243.200 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE STORAGE... Procedures § 243.200 Storage. ...

40 CFR 243.200 - Storage.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Storage. 243.200 Section 243.200 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE STORAGE... Procedures § 243.200 Storage. ...

40 CFR 243.200 - Storage.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Storage. 243.200 Section 243.200 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE STORAGE... Procedures § 243.200 Storage. ...

40 CFR 243.200 - Storage.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Storage. 243.200 Section 243.200 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE STORAGE... Procedures § 243.200 Storage. ...

40 CFR 243.200 - Storage.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Storage. 243.200 Section 243.200 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE STORAGE... Procedures § 243.200 Storage. ...

75 FR 17757 - Proposed Information Collection; OMB Control Number 1018-0022; Federal Fish and Wildlife License...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-07

... 700 1.25 hours......... 875 3-200-12 - Raptor Propagation... 50 50 4 hours 200 3-200-13 - Depredation... Abatement Activities Using Raptors*. 3-200-81--Special Purpose-- 30 30 2 hours 60 Utility. 3-200-82--Eagle... - Special Purpose 125 125 30 minutes......... 63 Miscellaneous Annual Report. 3-202-8 - Raptor Propagation...

75 FR 38009 - Airworthiness Directives; The Boeing Company Model 737-200, -300, -400, -500, -600, -700, -800...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-01

... Airworthiness Directives; The Boeing Company Model 737-200, -300, -400, -500, -600, -700, -800, and -900 Series Airplanes; Model 747-400 Series Airplanes; Model 757-200 and 757-300 Series Airplanes; Model 767-200, 767..., -500, -600, -700, -800, and -900 series airplanes; Model 747-400 series airplanes; Model 757-200 and...

Epigenetic modulation of the miR-200 family is associated with transition to a breast cancer stem-cell-like state.

PubMed

Lim, Yat-Yuen; Wright, Josephine A; Attema, Joanne L; Gregory, Philip A; Bert, Andrew G; Smith, Eric; Thomas, Daniel; Lopez, Angel F; Drew, Paul A; Khew-Goodall, Yeesim; Goodall, Gregory J

2013-05-15

The miR-200 family is a key regulator of the epithelial-mesenchymal transition, however, its role in controlling the transition between cancer stem-cell-like and non-stem-cell-like phenotypes is not well understood. We utilized immortalized human mammary epithelial (HMLE) cells to investigate the regulation of the miR-200 family during their conversion to a stem-like phenotype. HMLE cells were found to be capable of spontaneous conversion from a non-stem to a stem-like phenotype and this conversion was accompanied by the loss of miR-200 expression. Stem-like cell fractions isolated from metastatic breast cancers also displayed loss of miR-200 indicating similar molecular changes may occur during breast cancer progression. The phenotypic change observed in HMLE cells was directly controlled by miR-200 because restoration of its expression decreased stem-like properties while promoting a transition to an epithelial phenotype. Investigation of the mechanisms controlling miR-200 expression revealed both DNA methylation and histone modifications were significantly altered in the stem-like and non-stem phenotypes. In particular, in the stem-like phenotype, the miR-200b-200a-429 cluster was silenced primarily through polycomb group-mediated histone modifications whereas the miR-200c-141 cluster was repressed by DNA methylation. These results indicate that the miR-200 family plays a crucial role in the transition between stem-like and non-stem phenotypes and that distinct epigenetic-based mechanisms regulate each miR-200 gene in this process. Therapy targeted against miR-200 family members and epigenetic modifications might therefore be applicable to breast cancer.

Interplay Between Long Noncoding RNA ZEB1-AS1 and miR-200s Regulates Osteosarcoma Cell Proliferation and Migration.

PubMed

Liu, Chibo; Pan, Chunqin; Cai, Yanqun; Wang, Haibao

2017-08-01

In our previous study, we found long noncoding RNA ZEB1-AS1 is upregulated and functions as an oncogene in osteosarcoma. MiR-200 family (miR-200s) functions as tumor suppressor via directly targeting ZEB1 in various cancers. In this study, we further investigate the potential interplay between ZEB1-AS1, miR-200s, and ZEB1 in osteosarcoma. Our results showed that ZEB1-AS1 functions as a molecular sponge for miR-200s and relieves the inhibition of ZEB1 caused by miR-200s. ZEB1-AS1 and miR-200s reciprocally negatively regulate each other. MiR-200s are downregulated in osteosarcoma tissues, and negatively correlated with ZEB1-AS1 and ZEB1 expression levels in osteosarcoma. Functional experiments showed that consistent with ZEB1-AS1 depletion, miR-200s overexpression and ZEB1 depletion both inhibit osteosarcoma cell proliferation and migration. Overexpression of miR-200s partially abolished the effects of ZEB1-AS1 on osteosarcoma cell proliferation and migration. Moreover, the combination of ZEB1-AS1 depletion and miR-200s overexpression significantly inhibits osteosarcoma cell proliferation and migration. In conclusion, this study revealed a novel regulatory mechanism between ZEB1-AS1, miR-200s, and ZEB1. The interplay between ZEB1-AS1 and miR-200s contributes to osteosarcoma cell proliferation and migration, and targeting this interplay could be a promising strategy for osteosarcoma treatment. J. Cell. Biochem. 118: 2250-2260, 2017. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

Involvement of the CD200 receptor complex in microglia activation in experimental glaucoma

PubMed Central

Taylor, Sarah; Calder, Claudia J.; Albon, Julie; Erichsen, Jonathan T.; Boulton, Micheal E.; Morgan, James E.

2013-01-01

The interaction of the myeloid restricted molecule CD200R with its widely expressed ligand CD200 is involved in the down-regulation of microglia activation. In the present study, we examined the involvement of CD200R in microglia activation in experimental ocular hypertension to determine the role of microglia activation in retinal ganglion cell (RGC) death, the key pathological event in glaucoma. Experimental glaucoma was induced in adult Brown Norway rats by sclerosis of the episcleral veins with the injection of hypertonic saline. Immunohistochemical methods were used to determine the involvement of microglia using GFAP, CD45, OX42 and OX41 and the involvement of CD200 and CD200R in the optic nerve head. Our data demonstrate the increased presence of microglia within the optic nerve head during ocular hypertension, identified by positive staining with OX42 and OX41. The peak of microglia correlates with peak in RGC death at days 20–27 (T3) post OHT induction. In addition, CD200 and CD200R positive cells were increased in ocular hypertensive eyes. Increased expression of CD200 was detected in the early phase (days 1–7; T1) of OHT and decreased over time, whilst the expression of CD200R was detected in the middle phase (days 20–27; T3) of OHT, correlating with the increase in microglia markers. Changes in the expression of CD200R/CD200 occur early in experimental glaucoma and precede the peak in microglia infiltration and RGC death, suggesting that CD200R-positive microglia play an important role in the initiation of RGC death during OHT, indicating a potential area for therapeutic intervention in treating glaucoma. PMID:21296076

AKAP200 promotes Notch stability by protecting it from Cbl/lysosome-mediated degradation in Drosophila melanogaster.

PubMed

Bala Tannan, Neeta; Collu, Giovanna; Humphries, Ashley C; Serysheva, Ekatherina; Weber, Ursula; Mlodzik, Marek

2018-01-01

AKAP200 is a Drosophila melanogaster member of the "A Kinase Associated Protein" family of scaffolding proteins, known for their role in the spatial and temporal regulation of Protein Kinase A (PKA) in multiple signaling contexts. Here, we demonstrate an unexpected function of AKAP200 in promoting Notch protein stability. In Drosophila, AKAP200 loss-of-function (LOF) mutants show phenotypes that resemble Notch LOF defects, including eye patterning and sensory organ specification defects. Through genetic interactions, we demonstrate that AKAP200 interacts positively with Notch in both the eye and the thorax. We further show that AKAP200 is part of a physical complex with Notch. Biochemical studies reveal that AKAP200 stabilizes endogenous Notch protein, and that it limits ubiquitination of Notch. Specifically, our genetic and biochemical evidence indicates that AKAP200 protects Notch from the E3-ubiquitin ligase Cbl, which targets Notch to the lysosomal pathway. Indeed, we demonstrate that the effect of AKAP200 on Notch levels depends on the lysosome. Interestingly, this function of AKAP200 is fully independent of its role in PKA signaling and independent of its ability to bind PKA. Taken together, our data indicate that AKAP200 is a novel tissue specific posttranslational regulator of Notch, maintaining high Notch protein levels and thus promoting Notch signaling.

Specificity protein 1 (Sp1) maintains basal epithelial expression of the miR-200 family: implications for epithelial-mesenchymal transition.

PubMed

Kolesnikoff, Natasha; Attema, Joanne L; Roslan, Suraya; Bert, Andrew G; Schwarz, Quenten P; Gregory, Philip A; Goodall, Gregory J

2014-04-18

Epithelial-mesenchymal transition (EMT) is required for the specification of tissues during embryonic development and is recapitulated during the metastatic progression of tumors. The miR-200 family plays a critical role in enforcing the epithelial state with their expression lost in cells undergoing EMT. EMT can be mediated by activation of the ZEB1 and ZEB2 (ZEB) transcription factors, which repress miR-200 expression via a self-reinforcing double negative feedback loop to promote the mesenchymal state. However, it remains unclear what factors drive and maintain epithelial-specific expression of miR-200 in the absence of EMT-inducing factors. Here, we show that the transcription factor Specificity Protein 1 (Sp1) binds to the miR-200b∼200a∼429 proximal promoter and activates miR-200 expression in epithelial cells. In mesenchymal cells, Sp1 expression is maintained, but its ability to activate the miR-200 promoter is perturbed by ZEB-mediated repression. Reduction of Sp1 expression caused changes in EMT-associated markers in epithelial cells. Furthermore, we observed co-expression of Sp1 and miR-200 during mouse embryonic development wherein miR-200 expression was only lost in regions with high ZEB expression. Together, these findings indicate that miR-200 family members require Sp1 to drive basal expression and to maintain an epithelial state.

40 CFR 272.200 - [Reserved

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 27 2014-07-01 2014-07-01 false [Reserved] 272.200 Section 272.200 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Arkansas § 272.200 [Reserved] ...

40 CFR 272.200 - [Reserved

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 27 2011-07-01 2011-07-01 false [Reserved] 272.200 Section 272.200 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Arkansas § 272.200 [Reserved] ...

40 CFR 272.200 - [Reserved

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 28 2012-07-01 2012-07-01 false [Reserved] 272.200 Section 272.200 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Arkansas § 272.200 [Reserved] ...

40 CFR 272.200 - [Reserved

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 28 2013-07-01 2013-07-01 false [Reserved] 272.200 Section 272.200 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Arkansas § 272.200 [Reserved] ...

40 CFR 272.200 - [Reserved

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 26 2010-07-01 2010-07-01 false [Reserved] 272.200 Section 272.200 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Arkansas § 272.200 [Reserved] ...

77 FR 55163 - Airworthiness Directives; Airbus Airplanes

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-07

... directive (AD) for certain Airbus Model A330-200, A330-300, A340-200, and A340- 300 series airplanes; and... Model A330-200, A330- 200 Freighter, A330-300, A340-200, and A340-300 series airplanes; and Model A340... measure, EASA issued AD 2011-0040 to require a one-time [detailed] inspection of the MLG (all types of...

44 CFR 206.200 - General.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false General. 206.200 Section 206.200 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY DISASTER ASSISTANCE FEDERAL DISASTER ASSISTANCE Public Assistance Project Administration § 206.200...

40 CFR 68.200 - Recordkeeping.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 15 2010-07-01 2010-07-01 false Recordkeeping. 68.200 Section 68.200 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CHEMICAL ACCIDENT PREVENTION PROVISIONS Other Requirements § 68.200 Recordkeeping. The owner or operator shall...

23 CFR 450.200 - Purpose.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 23 Highways 1 2012-04-01 2012-04-01 false Purpose. 450.200 Section 450.200 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PLANNING AND RESEARCH PLANNING ASSISTANCE AND STANDARDS Statewide Transportation Planning and Programming § 450.200 Purpose. The purpose of this subpart...

49 CFR 613.200 - Statewide transportation planning and programming.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 7 2012-10-01 2012-10-01 false Statewide transportation planning and programming. 613.200 Section 613.200 Transportation Other Regulations Relating to Transportation (Continued... Transportation Planning and Programming § 613.200 Statewide transportation planning and programming. The...

49 CFR 613.200 - Statewide transportation planning and programming.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 7 2014-10-01 2014-10-01 false Statewide transportation planning and programming. 613.200 Section 613.200 Transportation Other Regulations Relating to Transportation (Continued... Transportation Planning and Programming § 613.200 Statewide transportation planning and programming. The...

23 CFR 450.200 - Purpose.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 23 Highways 1 2013-04-01 2013-04-01 false Purpose. 450.200 Section 450.200 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PLANNING AND RESEARCH PLANNING ASSISTANCE AND STANDARDS Statewide Transportation Planning and Programming § 450.200 Purpose. The purpose of this subpart...

49 CFR 613.200 - Statewide transportation planning and programming.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 7 2013-10-01 2013-10-01 false Statewide transportation planning and programming. 613.200 Section 613.200 Transportation Other Regulations Relating to Transportation (Continued... Transportation Planning and Programming § 613.200 Statewide transportation planning and programming. The...

23 CFR 450.200 - Purpose.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 23 Highways 1 2014-04-01 2014-04-01 false Purpose. 450.200 Section 450.200 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PLANNING AND RESEARCH PLANNING ASSISTANCE AND STANDARDS Statewide Transportation Planning and Programming § 450.200 Purpose. The purpose of this subpart...

49 CFR 613.200 - Statewide transportation planning and programming.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 7 2010-10-01 2010-10-01 false Statewide transportation planning and programming. 613.200 Section 613.200 Transportation Other Regulations Relating to Transportation (Continued... Transportation Planning and Programming § 613.200 Statewide transportation planning and programming. The...

23 CFR 450.200 - Purpose.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 23 Highways 1 2010-04-01 2010-04-01 false Purpose. 450.200 Section 450.200 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PLANNING AND RESEARCH PLANNING ASSISTANCE AND STANDARDS Statewide Transportation Planning and Programming § 450.200 Purpose. The purpose of this subpart...

17 CFR 200.602 - Application.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Application. 200.602 Section 200.602 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION ORGANIZATION; CONDUCT... Programs or Activities Conducted by the Securities and Exchange Commission § 200.602 Application. This...

28 CFR 54.200 - Application.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Application. 54.200 Section 54.200 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Coverage § 54.200 Application...

49 CFR 613.200 - Statewide transportation planning and programming.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 7 2011-10-01 2011-10-01 false Statewide transportation planning and programming. 613.200 Section 613.200 Transportation Other Regulations Relating to Transportation (Continued... Transportation Planning and Programming § 613.200 Statewide transportation planning and programming. The...

23 CFR 450.200 - Purpose.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 23 Highways 1 2011-04-01 2011-04-01 false Purpose. 450.200 Section 450.200 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PLANNING AND RESEARCH PLANNING ASSISTANCE AND STANDARDS Statewide Transportation Planning and Programming § 450.200 Purpose. The purpose of this subpart...

Shaping Physiological Indices, Swimming Technique, and Their Influence on 200m Breaststroke Race in Young Swimmers

PubMed Central

Strzala, Marek; Stanula, Arkadiusz; Głab, Grzegorz; Glodzik, Jacek; Ostrowski, Andrzej; Kaca, Marcin; Nosiadek, Leszek

2015-01-01

The aim of this study was to investigate somatic properties and physiological capacity, and analyze kinematic parameters in the 200 m breaststroke swimming race. Twenty-seven male swimmers participated in the study. They were 15.7±1.98 years old. Their average height was 1.80 ± 0.02 m and lean body mass (LBM) was 62.45 ± 8.29 kg. Physiological exercise capacity was measured in two separate 90 sec. all-out tests, one for the arms and second for legs. During the tests total work of arm cranking (TWAR) and cycling (TWLG) as well as peak of VO2 for arm (VO2peakAR) and leg (VO2peakLG) were measured. The underwater swimmers body movements were recorded during the all-out swimming 200m breaststroke speed test using an underwater camera installed on a portable trolley. The swimming kinematic parameters and propulsive or non-propulsive movement phases of the arms and legs as well as average speed (V200), surface speed (V200surface) and swimming speed in turn zones (V200turns) were extracted. V200surface was significantly related to the percentage of leg propulsion and was shown to have large effect on VO2peakLG in the Cohen analysis. V200turns depended significantly on the indicators of physiological performance and body structure: TWAR, VO2peak LG and LBM, LBM, which in turn strongly determined the measured results of TWAR, TWLG, VO2peakAR and VO2peakLG. The V200turns and V200surface were strongly associated with V200, 0.92, p < 0.001 and 0.91, p < 0.001 respectively. In each lap of the 200m swimming there was an increased percentage of propulsion of limb movement observed simultaneously with a reduction in the gliding phase in the breaststroke cycles. Key points This study investigated the influence of the selected indicators of somatic properties and physiological capacity as well kinematic and coordination parameters on breaststroke swimming. In this observations the body’s functional capacity have an important impact on achieving good breaststroke swimming results, the V200 was moderately associated on VO2peakLG, moreover, separate V200turns depended with VO2peakLG and on LBM and TWAR. The speed of surface breaststroke swimming - V200surface similarly as V200turns had a very strong influence on the end result of V200 , 0.91, p<0.001 and 0.92, p<0.001 respectively. The ability to swim fast on the surface (V200surface) was positively and significantly associated with the percentage time of propulsion generation -LP in the breaststroke cycle. PMID:25729298

40 CFR 421.200 - Applicability: Description of the secondary mercury subcategory.

Code of Federal Regulations, 2010 CFR

2010-07-01

... secondary mercury subcategory. 421.200 Section 421.200 Protection of Environment ENVIRONMENTAL PROTECTION... CATEGORY Secondary Mercury Subcategory § 421.200 Applicability: Description of the secondary mercury... mercury from secondary mercury facilities processing recycled mercuric oxide batteries and other mercury...

40 CFR 246.200-1 - Requirements.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Requirements. 246.200-1 Section 246.200-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES SOURCE SEPARATION FOR MATERIALS RECOVERY GUIDELINES Requirements and Recommended Procedures § 246.200-1 Requirements...

40 CFR 246.200-1 - Requirements.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Requirements. 246.200-1 Section 246.200-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES SOURCE SEPARATION FOR MATERIALS RECOVERY GUIDELINES Requirements and Recommended Procedures § 246.200-1 Requirements...

40 CFR 246.200-1 - Requirements.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Requirements. 246.200-1 Section 246.200-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES SOURCE SEPARATION FOR MATERIALS RECOVERY GUIDELINES Requirements and Recommended Procedures § 246.200-1 Requirements...

40 CFR 421.200 - Applicability: Description of the secondary mercury subcategory.

Code of Federal Regulations, 2013 CFR

2013-07-01

... secondary mercury subcategory. 421.200 Section 421.200 Protection of Environment ENVIRONMENTAL PROTECTION... CATEGORY Secondary Mercury Subcategory § 421.200 Applicability: Description of the secondary mercury... mercury from secondary mercury facilities processing recycled mercuric oxide batteries and other mercury...

40 CFR 421.200 - Applicability: Description of the secondary mercury subcategory.

Code of Federal Regulations, 2011 CFR

2011-07-01

... secondary mercury subcategory. 421.200 Section 421.200 Protection of Environment ENVIRONMENTAL PROTECTION... CATEGORY Secondary Mercury Subcategory § 421.200 Applicability: Description of the secondary mercury... mercury from secondary mercury facilities processing recycled mercuric oxide batteries and other mercury...

40 CFR 421.200 - Applicability: Description of the secondary mercury subcategory.

Code of Federal Regulations, 2014 CFR

2014-07-01

... secondary mercury subcategory. 421.200 Section 421.200 Protection of Environment ENVIRONMENTAL PROTECTION... CATEGORY Secondary Mercury Subcategory § 421.200 Applicability: Description of the secondary mercury... mercury from secondary mercury facilities processing recycled mercuric oxide batteries and other mercury...

40 CFR 421.200 - Applicability: Description of the secondary mercury subcategory.

Code of Federal Regulations, 2012 CFR

2012-07-01

... secondary mercury subcategory. 421.200 Section 421.200 Protection of Environment ENVIRONMENTAL PROTECTION... CATEGORY Secondary Mercury Subcategory § 421.200 Applicability: Description of the secondary mercury... mercury from secondary mercury facilities processing recycled mercuric oxide batteries and other mercury...

17 CFR 200.10 - The Commission.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false The Commission. 200.10 Section 200.10 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION ORGANIZATION; CONDUCT AND ETHICS; AND INFORMATION AND REQUESTS Organization and Program Management General Organization § 200.10...

17 CFR 200.10 - The Commission.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 17 Commodity and Securities Exchanges 2 2013-04-01 2013-04-01 false The Commission. 200.10 Section 200.10 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION ORGANIZATION; CONDUCT AND ETHICS; AND INFORMATION AND REQUESTS Organization and Program Management General Organization § 200.10...

17 CFR 200.10 - The Commission.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 17 Commodity and Securities Exchanges 2 2011-04-01 2011-04-01 false The Commission. 200.10 Section 200.10 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION ORGANIZATION; CONDUCT AND ETHICS; AND INFORMATION AND REQUESTS Organization and Program Management General Organization § 200.10...

49 CFR 200.13 - Publication.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Publication. 200.13 Section 200.13 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION INFORMAL RULES OF PRACTICE FOR PASSENGER SERVICE § 200.13 Publication. (a) General notice of any...

10 CFR 830.200 - Scope.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Scope. 830.200 Section 830.200 Energy DEPARTMENT OF ENERGY NUCLEAR SAFETY MANAGEMENT Safety Basis Requirements § 830.200 Scope. This Subpart establishes safety basis requirements for hazard category 1, 2, and 3 DOE nuclear facilities. ...

2 CFR 200.301 - Performance measurement.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Performance measurement. 200.301 Section 200... § 200.301 Performance measurement. The Federal awarding agency must require the recipient to use OMB-approved governmentwide standard information collections when providing financial and performance...

34 CFR 682.200 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 34 Education 4 2014-07-01 2014-07-01 false Definitions. 682.200 Section 682.200 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION (CONTINUED) FEDERAL FAMILY EDUCATION LOAN (FFEL) PROGRAM General Provisions § 682.200...

17 CFR 200.507 - Declassification dates on derivative documents.

Code of Federal Regulations, 2011 CFR

2011-04-01

... derivative documents. 200.507 Section 200.507 Commodity and Securities Exchanges SECURITIES AND EXCHANGE... of National Security Information and Material § 200.507 Declassification dates on derivative... derivative document that derives its classification from the approved use of the classification guide of...

40 CFR 240.200-2 - Recommended procedures: Design.

Code of Federal Regulations, 2011 CFR

2011-07-01

....200-2 Section 240.200-2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.200-2 Recommended procedures: Design. (a) In addition to the residential and commercial wastes...

40 CFR 240.200-2 - Recommended procedures: Design.

Code of Federal Regulations, 2010 CFR

2010-07-01

....200-2 Section 240.200-2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.200-2 Recommended procedures: Design. (a) In addition to the residential and commercial wastes...

30 CFR 250.200 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... OPERATIONS IN THE OUTER CONTINENTAL SHELF Plans and Information General Information § 250.200 Definitions... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Definitions. 250.200 Section 250.200 Mineral... subpart are listed alphabetically below: CID means Conservation Information Document CZMA means Coastal...

17 CFR 200.550 - Purpose.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Purpose. 200.550 Section 200.550 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION ORGANIZATION; CONDUCT AND ETHICS; AND INFORMATION AND REQUESTS Regulations Pertaining to the Protection of the Environment § 200...

10 CFR 830.200 - Scope.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 4 2014-01-01 2014-01-01 false Scope. 830.200 Section 830.200 Energy DEPARTMENT OF ENERGY NUCLEAR SAFETY MANAGEMENT Safety Basis Requirements § 830.200 Scope. This Subpart establishes safety basis requirements for hazard category 1, 2, and 3 DOE nuclear facilities. ...

10 CFR 830.200 - Scope.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Scope. 830.200 Section 830.200 Energy DEPARTMENT OF ENERGY NUCLEAR SAFETY MANAGEMENT Safety Basis Requirements § 830.200 Scope. This Subpart establishes safety basis requirements for hazard category 1, 2, and 3 DOE nuclear facilities. ...

10 CFR 830.200 - Scope.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 4 2012-01-01 2012-01-01 false Scope. 830.200 Section 830.200 Energy DEPARTMENT OF ENERGY NUCLEAR SAFETY MANAGEMENT Safety Basis Requirements § 830.200 Scope. This Subpart establishes safety basis requirements for hazard category 1, 2, and 3 DOE nuclear facilities. ...

44 CFR 19.200 - Application.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Application. 19.200 Section 19.200 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF... RECEIVING FEDERAL FINANCIAL ASSISTANCE Coverage § 19.200 Application. Except as provided in §§ 19.205...

14 CFR 1253.200 - Application.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Application. 1253.200 Section 1253.200 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Coverage § 1253.200 Application...

49 CFR 200.13 - Publication.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 4 2013-10-01 2013-10-01 false Publication. 200.13 Section 200.13 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION INFORMAL RULES OF PRACTICE FOR PASSENGER SERVICE § 200.13 Publication. (a) General notice of any...

49 CFR 200.13 - Publication.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 4 2014-10-01 2014-10-01 false Publication. 200.13 Section 200.13 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION INFORMAL RULES OF PRACTICE FOR PASSENGER SERVICE § 200.13 Publication. (a) General notice of any...

49 CFR 200.13 - Publication.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 4 2012-10-01 2012-10-01 false Publication. 200.13 Section 200.13 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION INFORMAL RULES OF PRACTICE FOR PASSENGER SERVICE § 200.13 Publication. (a) General notice of any...

49 CFR 200.13 - Publication.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Publication. 200.13 Section 200.13 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION INFORMAL RULES OF PRACTICE FOR PASSENGER SERVICE § 200.13 Publication. (a) General notice of any...

Tumor-derived vaccines containing CD200 inhibit immune activation: implications for immunotherapy.

PubMed

Xiong, Zhengming; Ampudia-Mesias, Elisabet; Shaver, Rob; Horbinski, Craig M; Moertel, Christopher L; Olin, Michael R

2016-09-01

There are over 400 ongoing clinical trials using tumor-derived vaccines. This approach is especially attractive for many types of brain tumors, including glioblastoma, yet so far the clinical response is highly variable. One contributor to poor response is CD200, which acts as a checkpoint blockade, inducing immune tolerance. We demonstrate that, in response to vaccination, glioma-derived CD200 suppresses the anti-tumor immune response. In contrast, a CD200 peptide inhibitor that activates antigen-presenting cells overcomes immune tolerance. The addition of the CD200 inhibitor significantly increased leukocyte infiltration into the vaccine site, cytokine and chemokine production, and cytolytic activity. Our data therefore suggest that CD200 suppresses the immune system's response to vaccines, and that blocking CD200 could improve the efficacy of cancer immunotherapy.

[Pentax AWS-s200: Its Advantages and Possible Problems].

PubMed

Hashimoto, Yuichi; Asai, Takashi; Arai, Takero; Okuda, Yasuhisa

2016-02-01

The Pentax AWS-s200 (Hoya, Japan : s-200) is a new videolaryngoscope. Its weight is 190 g, and it is lighter than the original AWS (AWS-s100L: s-100). It has a USB port, and its screen is wider and clearer than the s-100. The INTROCK for the s-100 is all usable with the s-200. The target mark is positioned at the center of the screen in the s-200. We used the s-200 in 20 patients, and could see a full view of the glottis, and tracheal intubation was successful in all patients. But tracheal intubation was not smooth in 10 of 20 patients, mainly because the tube impacted the right arytenoid. We felt the target mark of the s-200 may be incorrectly positioned.

Inactivation of p53 in pterygium influence miR-200a expression resulting in ZEB1/ZEB2 up-regulation and EMT processing.

PubMed

Wu, Chueh-Wei; Peng, Mei-Ling; Yeh, Ken-Tu; Tsai, Yi-Yu; Chiang, Chun-Chi; Cheng, Ya-Wen

2016-05-01

Loss of p53 function has been linked to progression of pterygium. MiR-200a is known to be controlled by p53. Here, we hypothesize that expression of miR-200a and downstream ZEB1/ZEB2 genes are regulated epithelial-mesenchymal transition (EMT) involved in the pathogenesis and recurrence of pterygium. For this study, 120 primary pterygial samples were collected. Immunohistochemistry and real-time RT-PCR were performed to determine the expression of p53, p53 down-stream EMT associated protein and miR-200a. The molecular correlation of p53, miR-200a and downstream genes were confirmed using primary pterygium cells (PECs). Expression of miR-200a in pterygium tissues was significantly lower than in conjunctiva controls (p = 0.015). Up-regulated miR-200a levels were positively correlated with and p53 protein expression (p < 0.001). The miR-200a downstream ZEB1/ZEB1 protein expression were negative correlated with miR-200a expression. Cell model studies demonstrated that miR-200a controlled the EMT of PECs through up-regulated ZEB1, ZEB2 and Snail gene expression. Our study demonstrated that inactivation of p53 in pterygium may influence miR-200a, resulting in ZEB1/ZEB2 up-regulation and EMT processing of pterygium. Therefore, we suggest that expression of miR-200a play an important role in EMT processing and recurrence of pterygium. Copyright © 2016 Elsevier Ltd. All rights reserved.

Mitomycin C induces fibroblasts apoptosis and reduces epidural fibrosis by regulating miR-200b and its targeting of RhoE.

PubMed

Sun, Yu; Ge, Yingbin; Fu, Yuxuan; Yan, Lianqi; Cai, Jun; Shi, Kun; Cao, Xiaojian; Lu, Chun

2015-10-15

Mitomycin C (MMC) is known to reduce epidural fibrosis, but the underlying mechanisms have not yet been elucidated. Aberrant miR-200b expressions have been reported in multiple types of fibrotic tissues from many diseases. The aim of this study was to clarify the mechanism by which MMC induces fibroblasts apoptosis and reduces epidural fibrosis. The expression of miR-200b in human fibroblasts was determined after MMC treatment, and the targeted association between miR-200b and RhoE was determined using the luciferase activity assay. The effects of MMC and miR-200b on human fibroblasts apoptosis were evaluated using flow cytometry and western blot analysis. The effects of MMC and miR-200b on epidural fibrosis were evaluated using the Rydell classification, hydroxyproline content, apoptotic cell count and histological analysis. The study revealed that MMC could significantly downregulate miR-200b expression and induce human fibroblasts apoptosis. The direct downregulation of miR-200b could induce human fibroblasts apoptosis. Furthermore, we identified the binding sequence for miR-200b within the 3' untranslated region of RhoE. RhoE was confirmed to be a direct target of miR-200b, and RhoE itself acted as a promoter of fibroblasts apoptosis. The inhibition of miR-200b increased fibroblasts apoptosis and reduced epidural fibrosis in rats, which was in accordance with the effect of MMC. This study suggests that MMC induces fibroblasts apoptosis and reduces epidural fibrosis by regulating miR-200b expression and its targeting of RhoE. Copyright © 2015 Elsevier B.V. All rights reserved.

RNA recognition by a human antibody against brain cytoplasmic 200 RNA

PubMed Central

Jung, Euihan; Lee, Jungmin; Hong, Hyo Jeong; Park, Insoo; Lee, Younghoon

2014-01-01

Diverse functional RNAs participate in a wide range of cellular processes. The RNA structure is critical for function, either on its own or as a complex form with proteins and other ligands. Therefore, analysis of the RNA conformation in cells is essential for understanding their functional mechanisms. However, no appropriate methods have been established as yet. Here, we developed an efficient strategy for panning and affinity maturation of anti-RNA human monoclonal antibodies from a naïve antigen binding fragment (Fab) combinatorial phage library. Brain cytoplasmic 200 (BC200) RNA, which is also highly expressed in some tumors, was used as an RNA antigen. We identified MabBC200-A3 as the optimal binding antibody. Mutagenesis and SELEX experiments showed that the antibody recognized a domain of BC200 in a structure- and sequence-dependent manner. Various breast cancer cell lines were further examined for BC200 RNA expression using conventional hybridization and immunoanalysis with MabBC200-A3 to see whether the antibody specifically recognizes BC200 RNA among the total purified RNAs. The amounts of antibody-recognizable BC200 RNA were consistent with hybridization signals among the cell lines. Furthermore, the antibody was able to discriminate BC200 RNA from other RNAs, supporting the utility of this antibody as a specific RNA structure-recognizing probe. Intriguingly, however, when permeabilized cells were subjected to immunoanalysis instead of purified total RNA, the amount of antibody-recognizable RNA was not correlated with the cellular level of BC200 RNA, indicating that BC200 RNA exists as two distinct forms (antibody-recognizable and nonrecognizable) in breast cancer cells and that their distribution depends on the cell type. Our results clearly demonstrate that anti-RNA antibodies provide an effective novel tool for detecting and analyzing RNA conformation. PMID:24759090

Effects of Aloe barbadensis Mill. extract (AVH200®) on human blood T cell activity in vitro.

PubMed

Ahluwalia, Bani; Magnusson, Maria K; Isaksson, Stefan; Larsson, Fredrik; Öhman, Lena

2016-02-17

Aloe barbadensis Mill. (Aloe vera) is a widely used medicinal plant well reputed for its diverse therapeutic applications. It has been used for thousands of years in folk medicine to treat various conditions and the Aloe vera gel has been reported to possess anti-inflammatory as well as immunostimulatory and immunomodulatory properties. However, the mode of action is still unclear. The aim of this study was determine the effects of two well-defined A. barbadensis Mill. extracts AVH200® and AVE200 on human blood T cells in vitro. Peripheral blood mononuclear cells (PBMC) from healthy donors were stimulated polyclonally in the presence or absence of AVH200® and AVE200. The T cell phenotype was investigated by flow cytometry, cell proliferation was determined by CFSE dye and thymidine assay, respectively and cytokine secretion was determined by MSD® Multi-Spot Assay system and ELISA. The presence of AVH200® resulted in a reduced expression of CD25 among CD3(+) T cells and suppression of T cell proliferation in a dose dependent manner. Furthermore, AVH200® reduced the expression of CD28 on CD3(+) T cells. AVH200® also reduced the secretion of IL-2, IFN-γ and IL-17A in PBMC cultures. The AVH200® dose dependent reduction in T cell activation and proliferation recorded in the cell cultures was not due to apoptosis or cell death. Additionally, AVH200® was found to be more effective as compared to AVE200 in reducing T cell activation and proliferation. AVH200® has the potential to reduce the activation, proliferation and cytokine secretion of healthy human blood T cells. Our study suggests that AVH200® has a suppressive effect on human blood T cells in vitro. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

37 CFR 41.200 - Procedure; pendency.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 37 Patents, Trademarks, and Copyrights 1 2014-07-01 2014-07-01 false Procedure; pendency. 41.200 Section 41.200 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE PRACTICE BEFORE THE PATENT TRIAL AND APPEAL BOARD Patent Interferences § 41.200 Procedure...

40 CFR 180.200 - Dicloran; tolerances for residues.

Code of Federal Regulations, 2010 CFR

2010-07-01

....200 Section 180.200 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS TOLERANCES AND EXEMPTIONS FOR PESTICIDE CHEMICAL RESIDUES IN FOOD Specific Tolerances § 180.200..., postharvest 10 Celery 15 Cherry, sweet, postharvest 20 Cucumber 5 Endive 10 Garlic 5 Grape 10 Lettuce 10...

45 CFR 400.200 - Scope.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 2 2010-10-01 2010-10-01 false Scope. 400.200 Section 400.200 Public Welfare Regulations Relating to Public Welfare OFFICE OF REFUGEE RESETTLEMENT, ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES REFUGEE RESETTLEMENT PROGRAM Federal Funding § 400.200...

7 CFR 3052.200 - Audit requirements.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 15 2010-01-01 2010-01-01 false Audit requirements. 3052.200 Section 3052.200 Agriculture Regulations of the Department of Agriculture (Continued) OFFICE OF THE CHIEF FINANCIAL OFFICER, DEPARTMENT OF AGRICULTURE AUDITS OF STATES, LOCAL GOVERNMENTS, AND NON-PROFIT ORGANIZATIONS Audits § 3052.200...

40 CFR 240.200-1 - Requirement.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Requirement. 240.200-1 Section 240.200-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.200-1 Requirement...

40 CFR 240.200-1 - Requirement.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Requirement. 240.200-1 Section 240.200-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.200-1 Requirement...

48 CFR 1631.200 - Scope of subpart.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Scope of subpart. 1631.200 Section 1631.200 Federal Acquisition Regulations System OFFICE OF PERSONNEL MANAGEMENT FEDERAL EMPLOYEES... PROCEDURES Contracts With Commercial Organizations 1631.200 Scope of subpart. The cost principles under this...

24 CFR 200.36 - Financial reporting requirements.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Financial reporting requirements. 200.36 Section 200.36 Housing and Urban Development Regulations Relating to Housing and Urban... Regulations § 200.36 Financial reporting requirements. The mortgagor must comply with the financial reporting...

23 CFR 200.1 - Purpose.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 23 Highways 1 2011-04-01 2011-04-01 false Purpose. 200.1 Section 200.1 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CIVIL RIGHTS TITLE VI PROGRAM AND RELATED STATUTES-IMPLEMENTATION AND REVIEW PROCEDURES § 200.1 Purpose. To provide guidelines for: (a) Implementing the Federal Highway...

23 CFR 200.1 - Purpose.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 23 Highways 1 2010-04-01 2010-04-01 false Purpose. 200.1 Section 200.1 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CIVIL RIGHTS TITLE VI PROGRAM AND RELATED STATUTES-IMPLEMENTATION AND REVIEW PROCEDURES § 200.1 Purpose. To provide guidelines for: (a) Implementing the Federal Highway...

23 CFR 200.1 - Purpose.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 23 Highways 1 2014-04-01 2014-04-01 false Purpose. 200.1 Section 200.1 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CIVIL RIGHTS TITLE VI PROGRAM AND RELATED STATUTES-IMPLEMENTATION AND REVIEW PROCEDURES § 200.1 Purpose. To provide guidelines for: (a) Implementing the Federal Highway...

23 CFR 200.1 - Purpose.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 23 Highways 1 2013-04-01 2013-04-01 false Purpose. 200.1 Section 200.1 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CIVIL RIGHTS TITLE VI PROGRAM AND RELATED STATUTES-IMPLEMENTATION AND REVIEW PROCEDURES § 200.1 Purpose. To provide guidelines for: (a) Implementing the Federal Highway...

40 CFR 264.200 - Air emission standards.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 27 2012-07-01 2012-07-01 false Air emission standards. 264.200 Section 264.200 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES... Tank Systems § 264.200 Air emission standards. The owner or operator shall manage all hazardous waste...

40 CFR 264.200 - Air emission standards.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 26 2014-07-01 2014-07-01 false Air emission standards. 264.200 Section 264.200 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES... Tank Systems § 264.200 Air emission standards. The owner or operator shall manage all hazardous waste...

31 CFR 1022.200 - General.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false General. 1022.200 Section 1022.200 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FINANCIAL CRIMES ENFORCEMENT NETWORK, DEPARTMENT OF THE TREASURY RULES FOR MONEY SERVICES BUSINESSES Programs § 1022.200...

31 CFR 1022.200 - General.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false General. 1022.200 Section 1022.200 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FINANCIAL CRIMES ENFORCEMENT NETWORK, DEPARTMENT OF THE TREASURY RULES FOR MONEY SERVICES BUSINESSES Programs § 1022.200...

31 CFR 1022.200 - General.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 31 Money and Finance:Treasury 3 2012-07-01 2012-07-01 false General. 1022.200 Section 1022.200 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FINANCIAL CRIMES ENFORCEMENT NETWORK, DEPARTMENT OF THE TREASURY RULES FOR MONEY SERVICES BUSINESSES Programs § 1022.200...

31 CFR 1022.200 - General.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false General. 1022.200 Section 1022.200 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FINANCIAL CRIMES ENFORCEMENT NETWORK, DEPARTMENT OF THE TREASURY RULES FOR MONEY SERVICES BUSINESSES Programs § 1022.200...

20 CFR 416.200 - Introduction.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 20 Employees' Benefits 2 2013-04-01 2013-04-01 false Introduction. 416.200 Section 416.200 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility General § 416.200 Introduction. You are eligible for SSI benefits if you meet all the...

20 CFR 416.200 - Introduction.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false Introduction. 416.200 Section 416.200 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility General § 416.200 Introduction. You are eligible for SSI benefits if you meet all the...

20 CFR 416.200 - Introduction.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false Introduction. 416.200 Section 416.200 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility General § 416.200 Introduction. You are eligible for SSI benefits if you meet all the...

20 CFR 416.200 - Introduction.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Introduction. 416.200 Section 416.200 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility General § 416.200 Introduction. You are eligible for SSI benefits if you meet all the...

20 CFR 416.200 - Introduction.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Introduction. 416.200 Section 416.200 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility General § 416.200 Introduction. You are eligible for SSI benefits if you meet all the...

40 CFR 264.200 - Air emission standards.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Air emission standards. 264.200 Section 264.200 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES... Tank Systems § 264.200 Air emission standards. The owner or operator shall manage all hazardous waste...

40 CFR 264.200 - Air emission standards.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Air emission standards. 264.200 Section 264.200 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES... Tank Systems § 264.200 Air emission standards. The owner or operator shall manage all hazardous waste...

2 CFR 200.83 - Project cost.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Project cost. 200.83 Section 200.83 Grants... AND BUDGET GUIDANCE Reserved UNIFORM ADMINISTRATIVE REQUIREMENTS, COST PRINCIPLES, AND AUDIT REQUIREMENTS FOR FEDERAL AWARDS Acronyms and Definitions Acronyms § 200.83 Project cost. Project cost means...

40 CFR 246.200-7 - Recommended procedures: Transportation.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Recommended procedures: Transportation. 246.200-7 Section 246.200-7 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... § 246.200-7 Recommended procedures: Transportation. Transportation to market may be supplied by the...

40 CFR 246.200-7 - Recommended procedures: Transportation.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Recommended procedures: Transportation. 246.200-7 Section 246.200-7 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... § 246.200-7 Recommended procedures: Transportation. Transportation to market may be supplied by the...

40 CFR 246.200-7 - Recommended procedures: Transportation.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Recommended procedures: Transportation. 246.200-7 Section 246.200-7 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... § 246.200-7 Recommended procedures: Transportation. Transportation to market may be supplied by the...

40 CFR 246.200-7 - Recommended procedures: Transportation.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Recommended procedures: Transportation. 246.200-7 Section 246.200-7 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... § 246.200-7 Recommended procedures: Transportation. Transportation to market may be supplied by the...

17 CFR 200.510 - Access by historical researchers.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 17 Commodity and Securities Exchanges 2 2011-04-01 2011-04-01 false Access by historical researchers. 200.510 Section 200.510 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION... Security Information and Material § 200.510 Access by historical researchers. (a) Persons outside the...

17 CFR 200.510 - Access by historical researchers.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 17 Commodity and Securities Exchanges 2 2012-04-01 2012-04-01 false Access by historical researchers. 200.510 Section 200.510 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION... Security Information and Material § 200.510 Access by historical researchers. (a) Persons outside the...

17 CFR 200.510 - Access by historical researchers.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 17 Commodity and Securities Exchanges 2 2013-04-01 2013-04-01 false Access by historical researchers. 200.510 Section 200.510 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION... Security Information and Material § 200.510 Access by historical researchers. (a) Persons outside the...

17 CFR 200.735-5 - Securities transactions.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 17 Commodity and Securities Exchanges 2 2012-04-01 2012-04-01 false Securities transactions. 200.735-5 Section 200.735-5 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION... Employees and Former Members and Employees of the Commission § 200.735-5 Securities transactions. Securities...

17 CFR 200.735-5 - Securities transactions.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 17 Commodity and Securities Exchanges 2 2011-04-01 2011-04-01 false Securities transactions. 200.735-5 Section 200.735-5 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION... Employees and Former Members and Employees of the Commission § 200.735-5 Securities transactions. Securities...

17 CFR 200.735-5 - Securities transactions.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 17 Commodity and Securities Exchanges 2 2013-04-01 2013-04-01 false Securities transactions. 200.735-5 Section 200.735-5 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION... Employees and Former Members and Employees of the Commission § 200.735-5 Securities transactions. Securities...

17 CFR 200.735-16 - Delegation.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 17 Commodity and Securities Exchanges 2 2011-04-01 2011-04-01 false Delegation. 200.735-16 Section 200.735-16 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION ORGANIZATION; CONDUCT... Former Members and Employees of the Commission § 200.735-16 Delegation. Any official responsibility...

17 CFR 200.735-16 - Delegation.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Delegation. 200.735-16 Section 200.735-16 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION ORGANIZATION; CONDUCT... Former Members and Employees of the Commission § 200.735-16 Delegation. Any official responsibility...

24 CFR 200.76 - Smoke detectors.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Smoke detectors. 200.76 Section 200.76 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued... Eligibility Requirements for Existing Projects Property Requirements § 200.76 Smoke detectors. Smoke detectors...

24 CFR 200.76 - Smoke detectors.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Smoke detectors. 200.76 Section 200.76 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued... Eligibility Requirements for Existing Projects Property Requirements § 200.76 Smoke detectors. Smoke detectors...

24 CFR 200.76 - Smoke detectors.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Smoke detectors. 200.76 Section 200.76 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued... Eligibility Requirements for Existing Projects Property Requirements § 200.76 Smoke detectors. Smoke detectors...

24 CFR 200.76 - Smoke detectors.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Smoke detectors. 200.76 Section 200.76 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued... Eligibility Requirements for Existing Projects Property Requirements § 200.76 Smoke detectors. Smoke detectors...

24 CFR 200.76 - Smoke detectors.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 2 2013-04-01 2013-04-01 false Smoke detectors. 200.76 Section 200.76 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued... Eligibility Requirements for Existing Projects Property Requirements § 200.76 Smoke detectors. Smoke detectors...

23 CFR 200.9 - State highway agency responsibilities.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 23 Highways 1 2012-04-01 2012-04-01 false State highway agency responsibilities. 200.9 Section 200.9 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CIVIL RIGHTS TITLE VI PROGRAM AND RELATED STATUTES-IMPLEMENTATION AND REVIEW PROCEDURES § 200.9 State highway agency...

40 CFR 240.200 - Solid wastes accepted.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Solid wastes accepted. 240.200 Section 240.200 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.200 Solid...

40 CFR 240.200 - Solid wastes accepted.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Solid wastes accepted. 240.200 Section 240.200 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.200 Solid...

29 CFR 2530.200b-5 - Seasonal industries. [Reserved

Code of Federal Regulations, 2014 CFR

2014-07-01

... 29 Labor 9 2014-07-01 2014-07-01 false Seasonal industries. [Reserved] 2530.200b-5 Section 2530.200b-5 Labor Regulations Relating to Labor (Continued) EMPLOYEE BENEFITS SECURITY ADMINISTRATION... and General Provisions § 2530.200b-5 Seasonal industries. [Reserved] ...

29 CFR 2530.200b-5 - Seasonal industries. [Reserved

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 9 2010-07-01 2010-07-01 false Seasonal industries. [Reserved] 2530.200b-5 Section 2530.200b-5 Labor Regulations Relating to Labor (Continued) EMPLOYEE BENEFITS SECURITY ADMINISTRATION... and General Provisions § 2530.200b-5 Seasonal industries. [Reserved] ...

29 CFR 2530.200b-5 - Seasonal industries. [Reserved

Code of Federal Regulations, 2012 CFR

2012-07-01

... 29 Labor 9 2012-07-01 2012-07-01 false Seasonal industries. [Reserved] 2530.200b-5 Section 2530.200b-5 Labor Regulations Relating to Labor (Continued) EMPLOYEE BENEFITS SECURITY ADMINISTRATION... and General Provisions § 2530.200b-5 Seasonal industries. [Reserved] ...

29 CFR 2530.200b-5 - Seasonal industries. [Reserved

Code of Federal Regulations, 2013 CFR

2013-07-01

... 29 Labor 9 2013-07-01 2013-07-01 false Seasonal industries. [Reserved] 2530.200b-5 Section 2530.200b-5 Labor Regulations Relating to Labor (Continued) EMPLOYEE BENEFITS SECURITY ADMINISTRATION... and General Provisions § 2530.200b-5 Seasonal industries. [Reserved] ...

29 CFR 2530.200b-5 - Seasonal industries. [Reserved

Code of Federal Regulations, 2011 CFR

2011-07-01

... 29 Labor 9 2011-07-01 2011-07-01 false Seasonal industries. [Reserved] 2530.200b-5 Section 2530.200b-5 Labor Regulations Relating to Labor (Continued) EMPLOYEE BENEFITS SECURITY ADMINISTRATION... and General Provisions § 2530.200b-5 Seasonal industries. [Reserved] ...

46 CFR 403.200 - General.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 8 2010-10-01 2010-10-01 false General. 403.200 Section 403.200 Shipping COAST GUARD (GREAT LAKES PILOTAGE), DEPARTMENT OF HOMELAND SECURITY GREAT LAKES PILOTAGE UNIFORM ACCOUNTING SYSTEM Inter-Association Settlements § 403.200 General. Each Association that shares revenues and expenses with...

20 CFR 665.200 - What are required Statewide workforce investment activities?

Code of Federal Regulations, 2010 CFR

2010-04-01

... investment activities? 665.200 Section 665.200 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR STATEWIDE WORKFORCE INVESTMENT ACTIVITIES UNDER TITLE I OF THE WORKFORCE INVESTMENT ACT Required and Allowable Statewide Workforce Investment Activities § 665.200 What are required Statewide...

37 CFR 41.200 - Procedure; pendency.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 37 Patents, Trademarks, and Copyrights 1 2013-07-01 2013-07-01 false Procedure; pendency. 41.200 Section 41.200 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE PRACTICE BEFORE THE PATENT TRIAL AND APPEAL BOARD Patent Interferences § 41.200 Procedure...

17 CFR 200.50 - Authority.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Authority. 200.50 Section 200.50 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION ORGANIZATION; CONDUCT AND ETHICS; AND INFORMATION AND REQUESTS Canons of Ethics § 200.50 Authority. The Canons of Ethics for...

46 CFR 308.200 - Insured amount-application.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 8 2013-10-01 2013-10-01 false Insured amount-application. 308.200 Section 308.200 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Protection and Indemnity Insurance § 308.200 Insured amount—application. An applicant for war risk...

46 CFR 308.200 - Insured amount-application.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 8 2010-10-01 2010-10-01 false Insured amount-application. 308.200 Section 308.200 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Protection and Indemnity Insurance § 308.200 Insured amount—application. An applicant for war risk...

46 CFR 308.200 - Insured amount-application.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 8 2011-10-01 2011-10-01 false Insured amount-application. 308.200 Section 308.200 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Protection and Indemnity Insurance § 308.200 Insured amount—application. An applicant for war risk...

46 CFR 308.200 - Insured amount-application.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 8 2012-10-01 2012-10-01 false Insured amount-application. 308.200 Section 308.200 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Protection and Indemnity Insurance § 308.200 Insured amount—application. An applicant for war risk...

46 CFR 308.200 - Insured amount-application.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 8 2014-10-01 2014-10-01 false Insured amount-application. 308.200 Section 308.200 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Protection and Indemnity Insurance § 308.200 Insured amount—application. An applicant for war risk...

24 CFR 200.15 - Maximum mortgage.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Maximum mortgage. 200.15 Section 200.15 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued... Eligibility Requirements for Existing Projects Eligible Mortgage § 200.15 Maximum mortgage. Mortgages must not...

17 CFR 200.507 - Declassification dates on derivative documents.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Declassification dates on derivative documents. 200.507 Section 200.507 Commodity and Securities Exchanges SECURITIES AND EXCHANGE... of National Security Information and Material § 200.507 Declassification dates on derivative...

24 CFR 200.17 - Mortgage coverage.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Mortgage coverage. 200.17 Section 200.17 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued... Eligibility Requirements for Existing Projects Eligible Mortgage § 200.17 Mortgage coverage. The mortgage...

24 CFR 200.17 - Mortgage coverage.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 2 2013-04-01 2013-04-01 false Mortgage coverage. 200.17 Section 200.17 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued... Eligibility Requirements for Existing Projects Eligible Mortgage § 200.17 Mortgage coverage. The mortgage...

43 CFR 41.200 - Application.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Application. 41.200 Section 41.200 Public Lands: Interior Office of the Secretary of the Interior NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Coverage § 41.200 Application...

7 CFR 948.200 - Accounting and collections.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 8 2010-01-01 2010-01-01 false Accounting and collections. 948.200 Section 948.200 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... Accounting and Collections § 948.200 Accounting and collections. (a) Each handler's assessment account with...

24 CFR 200.36 - Financial reporting requirements.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Financial reporting requirements. 200.36 Section 200.36 Housing and Urban Development Regulations Relating to Housing and Urban... Regulations § 200.36 Financial reporting requirements. The mortgagor must comply with the financial reporting...

TMBP200, a XMAP215 homologue of tobacco BY-2 cells, has an essential role in plant mitosis.

PubMed

Yasuhara, Hiroki; Oe, Yuki

2011-07-01

TMBP200 from tobacco BY-2 cells is a member of the highly conserved family of microtubule-associated proteins that includes Xenopus XMAP215, human TOGp, and Arabidopsis MOR1/GEM1. XMAP215 homologues have an essential role in spindle assembly and function in animals and yeast, but their role in plant mitosis is not fully clarified. Here, we show by immunoblot analysis that TMBP200 levels in synchronously cultured BY-2 cells increased when the cells entered mitosis, thus indicating that TMBP200 plays an important role in mitosis in tobacco. To investigate the role of TMBP200 in mitosis, we employed inducible RNA interference to silence TMBP200 expression in BY-2 cells. The resulting depletion of TMBP200 caused severe defects in bipolar spindle formation and resulted in the appearance of multinucleated cells with variable-sized nuclei. This finding indicates that TMBP200 has an essential role in bipolar spindle formation and function.

Drosophila Fip200 is an essential regulator of autophagy that attenuates both growth and aging.

PubMed

Kim, Myungjin; Park, Hae Li; Park, Hwan-Woo; Ro, Seung-Hyun; Nam, Samuel G; Reed, John M; Guan, Jun-Lin; Lee, Jun Hee

2013-08-01

Autophagy-related 1 (Atg1)/Unc-51-like protein kinases (ULKs) are evolutionarily conserved proteins that play critical physiological roles in controlling autophagy, cell growth and neurodevelopment. RB1-inducible coiled-coil 1 (RB1CC1), also known as PTK2/FAK family-interacting protein of 200 kDa (FIP200) is a recently discovered binding partner of ULK1. Here we isolated the Drosophila RB1CC1/FIP200 homolog (Fip200/CG1347) and showed that it mediates Atg1-induced autophagy as a genetically downstream component in diverse physiological contexts. Fip200 loss-of-function mutants experienced severe mobility loss associated with neuronal autophagy defects and neurodegeneration. The Fip200 mutants were also devoid of both developmental and starvation-induced autophagy in salivary gland and fat body, while having no defects in axonal transport and projection in developing neurons. Interestingly, moderate downregulation of Fip200 accelerated both developmental growth and aging, accompanied by target of rapamycin (Tor) signaling upregulation. These results suggest that Fip200 is a critical downstream component of Atg1 and specifically mediates Atg1's autophagy-, aging- and growth-regulating functions.

Drosophila Fip200 is an essential regulator of autophagy that attenuates both growth and aging

PubMed Central

Kim, Myungjin; Park, Hae Li; Park, Hwan-Woo; Ro, Seung-Hyun; Nam, Samuel G.; Reed, John M.; Guan, Jun-Lin; Lee, Jun Hee

2013-01-01

Autophagy-related 1 (Atg1)/Unc-51-like protein kinases (ULKs) are evolutionarily conserved proteins that play critical physiological roles in controlling autophagy, cell growth and neurodevelopment. RB1-inducible coiled-coil 1 (RB1CC1), also known as PTK2/FAK family-interacting protein of 200 kDa (FIP200) is a recently discovered binding partner of ULK1. Here we isolated the Drosophila RB1CC1/FIP200 homolog (Fip200/CG1347) and showed that it mediates Atg1-induced autophagy as a genetically downstream component in diverse physiological contexts. Fip200 loss-of-function mutants experienced severe mobility loss associated with neuronal autophagy defects and neurodegeneration. The Fip200 mutants were also devoid of both developmental and starvation-induced autophagy in salivary gland and fat body, while having no defects in axonal transport and projection in developing neurons. Interestingly, moderate downregulation of Fip200 accelerated both developmental growth and aging, accompanied by target of rapamycin (Tor) signaling upregulation. These results suggest that Fip200 is a critical downstream component of Atg1 and specifically mediates Atg1’s autophagy-, aging- and growth-regulating functions. PMID:23819996

Binding Affinity, Specificity and Comparative Biodistribution of the Parental Murine Monoclonal Antibody MX35 (Anti-NaPi2b) and Its Humanized Version Rebmab200

PubMed Central

Lindegren, Sture; Andrade, Luciana N. S.; Bäck, Tom; Machado, Camila Maria L.; Horta, Bruno Brasil; Buchpiguel, Carlos; Moro, Ana Maria; Okamoto, Oswaldo Keith; Jacobsson, Lars; Cederkrantz, Elin; Washiyama, Kohshin; Aneheim, Emma; Palm, Stig; Jensen, Holger; Tuma, Maria Carolina B.; Chammas, Roger; Hultborn, Ragnar; Albertsson, Per

2015-01-01

The aim of this preclinical study was to evaluate the characteristics of the monoclonal antibody Rebmab200, which is a humanized version of the ovarian-specific murine antibody MX35. This investigation contributes to the foundation for future clinical α-radioimmunotherapy of minimal residual ovarian cancer with 211At-Rebmab200. Here, the biodistribution of 211At-Rebmab200 was evaluated, as was the utility of 99mTc-Rebmab200 for bioimaging. Rebmab200 was directly compared with its murine counterpart MX35 in terms of its in-vitro capacity for binding the immobilized NaPi2B epitope and live cells; we also assessed its biodistribution in nude mice carrying subcutaneous OVCAR-3 tumors. Tumor antigen and cell binding were similar between Rebmab200 and murine MX35, as was biodistribution, including normal tissue uptake and in-vivo tumor binding. We also demonstrated that 99mTc-Rebmab200 can be used for single-photon emission computed tomography of subcutaneous ovarian carcinomas in tumor-bearing mice. Taken together, our data support the further development of Rebmab200 for radioimmunotherapy and diagnostics. PMID:25970341

Binding Affinity, Specificity and Comparative Biodistribution of the Parental Murine Monoclonal Antibody MX35 (Anti-NaPi2b) and Its Humanized Version Rebmab200.

PubMed

Lindegren, Sture; Andrade, Luciana N S; Bäck, Tom; Machado, Camila Maria L; Horta, Bruno Brasil; Buchpiguel, Carlos; Moro, Ana Maria; Okamoto, Oswaldo Keith; Jacobsson, Lars; Cederkrantz, Elin; Washiyama, Kohshin; Aneheim, Emma; Palm, Stig; Jensen, Holger; Tuma, Maria Carolina B; Chammas, Roger; Hultborn, Ragnar; Albertsson, Per

2015-01-01

The aim of this preclinical study was to evaluate the characteristics of the monoclonal antibody Rebmab200, which is a humanized version of the ovarian-specific murine antibody MX35. This investigation contributes to the foundation for future clinical α-radioimmunotherapy of minimal residual ovarian cancer with 211At-Rebmab200. Here, the biodistribution of 211At-Rebmab200 was evaluated, as was the utility of 99mTc-Rebmab200 for bioimaging. Rebmab200 was directly compared with its murine counterpart MX35 in terms of its in-vitro capacity for binding the immobilized NaPi2B epitope and live cells; we also assessed its biodistribution in nude mice carrying subcutaneous OVCAR-3 tumors. Tumor antigen and cell binding were similar between Rebmab200 and murine MX35, as was biodistribution, including normal tissue uptake and in-vivo tumor binding. We also demonstrated that 99mTc-Rebmab200 can be used for single-photon emission computed tomography of subcutaneous ovarian carcinomas in tumor-bearing mice. Taken together, our data support the further development of Rebmab200 for radioimmunotherapy and diagnostics.

40 CFR 180.200 - Dicloran; tolerances for residues.

Code of Federal Regulations, 2011 CFR

2011-07-01

....200 Section 180.200 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS TOLERANCES AND EXEMPTIONS FOR PESTICIDE CHEMICAL RESIDUES IN FOOD Specific Tolerances § 180.200... None Endive 10 None Garlic 5 None Grape 10 None Lettuce 10 None Nectarine, postharvest 20 None Onion 10...

33 CFR 103.200 - Designation of the Federal Maritime Security Coordinator (FMSC).

Code of Federal Regulations, 2010 CFR

2010-07-01

... Maritime Security Coordinator (FMSC). 103.200 Section 103.200 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY MARITIME SECURITY MARITIME SECURITY: AREA MARITIME SECURITY Federal Maritime Security Coordinator (FMSC) Designation and Authorities § 103.200 Designation of the Federal Maritime...

42 CFR 402.200 - Basis and purpose.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 42 Public Health 2 2013-10-01 2013-10-01 false Basis and purpose. 402.200 Section 402.200 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS CIVIL MONEY PENALTIES, ASSESSMENTS, AND EXCLUSIONS Exclusions § 402.200 Basis and purpose. (a...

42 CFR 402.200 - Basis and purpose.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 2 2014-10-01 2014-10-01 false Basis and purpose. 402.200 Section 402.200 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS CIVIL MONEY PENALTIES, ASSESSMENTS, AND EXCLUSIONS Exclusions § 402.200 Basis and purpose. (a...

42 CFR 402.200 - Basis and purpose.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 2 2010-10-01 2010-10-01 false Basis and purpose. 402.200 Section 402.200 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS CIVIL MONEY PENALTIES, ASSESSMENTS, AND EXCLUSIONS Exclusions § 402.200 Basis and purpose. (a...

42 CFR 402.200 - Basis and purpose.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 2 2011-10-01 2011-10-01 false Basis and purpose. 402.200 Section 402.200 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS CIVIL MONEY PENALTIES, ASSESSMENTS, AND EXCLUSIONS Exclusions § 402.200 Basis and purpose. (a...

42 CFR 402.200 - Basis and purpose.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 42 Public Health 2 2012-10-01 2012-10-01 false Basis and purpose. 402.200 Section 402.200 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS CIVIL MONEY PENALTIES, ASSESSMENTS, AND EXCLUSIONS Exclusions § 402.200 Basis and purpose. (a...

45 CFR 604.200 - Agency and legislative liaison.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 3 2010-10-01 2010-10-01 false Agency and legislative liaison. 604.200 Section 604.200 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION NEW RESTRICTIONS ON LOBBYING Activities by Own Employees § 604.200 Agency and legislative liaison. (a...

48 CFR 50.200 - Scope of subpart.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false Scope of subpart. 50.200 Section 50.200 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT... Act of 2002 50.200 Scope of subpart. This subpart implements the Support Anti-terrorism by Fostering...

48 CFR 50.200 - Scope of subpart.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Scope of subpart. 50.200 Section 50.200 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT... Act of 2002 50.200 Scope of subpart. This subpart implements the Support Anti-terrorism by Fostering...

48 CFR 50.200 - Scope of subpart.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Scope of subpart. 50.200 Section 50.200 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT... Act of 2002 50.200 Scope of subpart. This subpart implements the Support Anti-terrorism by Fostering...

41 CFR 101-39.200 - Scope.

Code of Federal Regulations, 2010 CFR

2010-07-01

... MANAGEMENT SYSTEMS 39.2-GSA Interagency Fleet Management System Services § 101-39.200 Scope. This subpart... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Scope. 101-39.200 Section 101-39.200 Public Contracts and Property Management Federal Property Management Regulations System...

41 CFR 101-39.200 - Scope.

Code of Federal Regulations, 2011 CFR

2011-07-01

... MANAGEMENT SYSTEMS 39.2-GSA Interagency Fleet Management System Services § 101-39.200 Scope. This subpart... 41 Public Contracts and Property Management 2 2011-07-01 2007-07-01 true Scope. 101-39.200 Section 101-39.200 Public Contracts and Property Management Federal Property Management Regulations System...

41 CFR 101-39.200 - Scope.

Code of Federal Regulations, 2014 CFR

2014-07-01

... MANAGEMENT SYSTEMS 39.2-GSA Interagency Fleet Management System Services § 101-39.200 Scope. This subpart... 41 Public Contracts and Property Management 2 2014-07-01 2012-07-01 true Scope. 101-39.200 Section 101-39.200 Public Contracts and Property Management Federal Property Management Regulations System...

27 CFR 200.55 - Content.

Code of Federal Regulations, 2010 CFR

1997-04-01

... 27 Alcohol, Tobacco Products and Firearms 2 1997-04-01 1997-04-01 false Content. 200.55 Section 200.55 ALCOHOL, TOBACCO AND OTHER EXCISE TAXES-Continued RULES OF PRACTICE IN PERMIT PROCEEDINGS Hearing Procedure Citations § 200.55 Content. (a) Citation for the suspension, revocation or annulment of...

27 CFR 200.55 - Content.

Code of Federal Regulations, 2010 CFR

1999-04-01

... 27 Alcohol, Tobacco Products and Firearms 2 1999-04-01 1999-04-01 false Content. 200.55 Section 200.55 ALCOHOL, TOBACCO AND OTHER EXCISE TAXES-Continued RULES OF PRACTICE IN PERMIT PROCEEDINGS Hearing Procedure Citations § 200.55 Content. (a) Citation for the suspension, revocation or annulment of...

19 CFR 200.735-103 - Counseling service.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 19 Customs Duties 3 2010-04-01 2010-04-01 false Counseling service. 200.735-103 Section 200.735-103 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION EMPLOYEE RESPONSIBILITIES AND CONDUCT General Provisions § 200.735-103 Counseling service. (a) The Chairman shall appoint a Designated Agency...

19 CFR 200.735-103 - Counseling service.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 19 Customs Duties 3 2011-04-01 2011-04-01 false Counseling service. 200.735-103 Section 200.735-103 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION EMPLOYEE RESPONSIBILITIES AND CONDUCT General Provisions § 200.735-103 Counseling service. (a) The Chairman shall appoint a Designated Agency...

19 CFR 200.735-103 - Counseling service.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 19 Customs Duties 3 2013-04-01 2013-04-01 false Counseling service. 200.735-103 Section 200.735-103 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION EMPLOYEE RESPONSIBILITIES AND CONDUCT General Provisions § 200.735-103 Counseling service. (a) The Chairman shall appoint a Designated Agency...

19 CFR 200.735-103 - Counseling service.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 19 Customs Duties 3 2014-04-01 2014-04-01 false Counseling service. 200.735-103 Section 200.735-103 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION EMPLOYEE RESPONSIBILITIES AND CONDUCT General Provisions § 200.735-103 Counseling service. (a) The Chairman shall appoint a Designated Agency...

19 CFR 200.735-103 - Counseling service.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 19 Customs Duties 3 2012-04-01 2012-04-01 false Counseling service. 200.735-103 Section 200.735-103 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION EMPLOYEE RESPONSIBILITIES AND CONDUCT General Provisions § 200.735-103 Counseling service. (a) The Chairman shall appoint a Designated Agency...

34 CFR 200.39 - Responsibilities resulting from identification for school improvement.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 34 Education 1 2011-07-01 2011-07-01 false Responsibilities resulting from identification for school improvement. 200.39 Section 200.39 Education Regulations of the Offices of the Department of... Lea and School Improvement § 200.39 Responsibilities resulting from identification for school...

34 CFR 200.39 - Responsibilities resulting from identification for school improvement.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 34 Education 1 2014-07-01 2014-07-01 false Responsibilities resulting from identification for school improvement. 200.39 Section 200.39 Education Regulations of the Offices of the Department of... Lea and School Improvement § 200.39 Responsibilities resulting from identification for school...

34 CFR 200.39 - Responsibilities resulting from identification for school improvement.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 34 Education 1 2012-07-01 2012-07-01 false Responsibilities resulting from identification for school improvement. 200.39 Section 200.39 Education Regulations of the Offices of the Department of... Lea and School Improvement § 200.39 Responsibilities resulting from identification for school...

34 CFR 200.39 - Responsibilities resulting from identification for school improvement.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 34 Education 1 2010-07-01 2010-07-01 false Responsibilities resulting from identification for school improvement. 200.39 Section 200.39 Education Regulations of the Offices of the Department of... Lea and School Improvement § 200.39 Responsibilities resulting from identification for school...

24 CFR 200.210 - Policy.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Policy. 200.210 Section 200.210 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF... Review and Clearance Procedure § 200.210 Policy. It is the Department's policy that participants in its...

43 CFR 17.200 - Purpose.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Purpose. 17.200 Section 17.200 Public Lands: Interior Office of the Secretary of the Interior NONDISCRIMINATION IN FEDERALLY ASSISTED PROGRAMS OF THE DEPARTMENT OF THE INTERIOR Nondiscrimination on the Basis of Handicap § 17.200 Purpose. The...

17 CFR 200.57 - Relationships with other members.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 17 Commodity and Securities Exchanges 2 2011-04-01 2011-04-01 false Relationships with other members. 200.57 Section 200.57 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION ORGANIZATION; CONDUCT AND ETHICS; AND INFORMATION AND REQUESTS Canons of Ethics § 200.57 Relationships with...

4 CFR 200.2 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-01-01

..., information regarding an individual's education, financial transactions, medical history, and criminal or... 4 Accounts 1 2011-01-01 2011-01-01 false Definitions. 200.2 Section 200.2 Accounts RECOVERY ACCOUNTABILITY AND TRANSPARENCY BOARD PRIVACY ACT OF 1974 § 200.2 Definitions. As used in this part: (a) Agency...

17 CFR 200.72 - Supervision of internal organization.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 17 Commodity and Securities Exchanges 2 2011-04-01 2011-04-01 false Supervision of internal organization. 200.72 Section 200.72 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION ORGANIZATION; CONDUCT AND ETHICS; AND INFORMATION AND REQUESTS Canons of Ethics § 200.72 Supervision of...

17 CFR 200.72 - Supervision of internal organization.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 17 Commodity and Securities Exchanges 2 2012-04-01 2012-04-01 false Supervision of internal organization. 200.72 Section 200.72 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION ORGANIZATION; CONDUCT AND ETHICS; AND INFORMATION AND REQUESTS Canons of Ethics § 200.72 Supervision of...

17 CFR 200.72 - Supervision of internal organization.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 17 Commodity and Securities Exchanges 3 2014-04-01 2014-04-01 false Supervision of internal organization. 200.72 Section 200.72 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION ORGANIZATION; CONDUCT AND ETHICS; AND INFORMATION AND REQUESTS Canons of Ethics § 200.72 Supervision of...

17 CFR 200.72 - Supervision of internal organization.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 17 Commodity and Securities Exchanges 2 2013-04-01 2013-04-01 false Supervision of internal organization. 200.72 Section 200.72 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION ORGANIZATION; CONDUCT AND ETHICS; AND INFORMATION AND REQUESTS Canons of Ethics § 200.72 Supervision of...

17 CFR 200.72 - Supervision of internal organization.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Supervision of internal organization. 200.72 Section 200.72 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION ORGANIZATION; CONDUCT AND ETHICS; AND INFORMATION AND REQUESTS Canons of Ethics § 200.72 Supervision of...

40 CFR 408.200 - Applicability; description of the Alaskan bottom fish processing subcategory.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Alaskan bottom fish processing subcategory. 408.200 Section 408.200 Protection of Environment... PROCESSING POINT SOURCE CATEGORY Alaskan Bottom Fish Processing Subcategory § 408.200 Applicability; description of the Alaskan bottom fish processing subcategory. The provisions of this subpart are applicable...

40 CFR 408.200 - Applicability; description of the Alaskan bottom fish processing subcategory.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Alaskan bottom fish processing subcategory. 408.200 Section 408.200 Protection of Environment... PROCESSING POINT SOURCE CATEGORY Alaskan Bottom Fish Processing Subcategory § 408.200 Applicability; description of the Alaskan bottom fish processing subcategory. The provisions of this subpart are applicable...

40 CFR 408.200 - Applicability; description of the Alaskan bottom fish processing subcategory.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Alaskan bottom fish processing subcategory. 408.200 Section 408.200 Protection of Environment... PROCESSING POINT SOURCE CATEGORY Alaskan Bottom Fish Processing Subcategory § 408.200 Applicability; description of the Alaskan bottom fish processing subcategory. The provisions of this subpart are applicable...

40 CFR 408.200 - Applicability; description of the Alaskan bottom fish processing subcategory.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Alaskan bottom fish processing subcategory. 408.200 Section 408.200 Protection of Environment... PROCESSING POINT SOURCE CATEGORY Alaskan Bottom Fish Processing Subcategory § 408.200 Applicability; description of the Alaskan bottom fish processing subcategory. The provisions of this subpart are applicable...

24 CFR 200.855 - Physical condition standards and physical inspection requirements.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Physical condition standards and physical inspection requirements. 200.855 Section 200.855 Housing and Urban Development Regulations... Physical Condition of Multifamily Properties § 200.855 Physical condition standards and physical inspection...

24 CFR 200.855 - Physical condition standards and physical inspection requirements.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 2 2013-04-01 2013-04-01 false Physical condition standards and physical inspection requirements. 200.855 Section 200.855 Housing and Urban Development Regulations... Physical Condition of Multifamily Properties § 200.855 Physical condition standards and physical inspection...

24 CFR 200.855 - Physical condition standards and physical inspection requirements.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Physical condition standards and physical inspection requirements. 200.855 Section 200.855 Housing and Urban Development Regulations... Physical Condition of Multifamily Properties § 200.855 Physical condition standards and physical inspection...

24 CFR 200.855 - Physical condition standards and physical inspection requirements.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Physical condition standards and physical inspection requirements. 200.855 Section 200.855 Housing and Urban Development Regulations... Physical Condition of Multifamily Properties § 200.855 Physical condition standards and physical inspection...

24 CFR 200.855 - Physical condition standards and physical inspection requirements.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Physical condition standards and physical inspection requirements. 200.855 Section 200.855 Housing and Urban Development Regulations... Physical Condition of Multifamily Properties § 200.855 Physical condition standards and physical inspection...

2 CFR 200.61 - Internal controls.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Internal controls. 200.61 Section 200.61 Grants and Agreements Office of Management and Budget Guidance for Grants and Agreements OFFICE OF... REQUIREMENTS FOR FEDERAL AWARDS Acronyms and Definitions Acronyms § 200.61 Internal controls. Internal controls...

40 CFR 408.200 - Applicability; description of the Alaskan bottom fish processing subcategory.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Alaskan bottom fish processing subcategory. 408.200 Section 408.200 Protection of Environment... PROCESSING POINT SOURCE CATEGORY Alaskan Bottom Fish Processing Subcategory § 408.200 Applicability; description of the Alaskan bottom fish processing subcategory. The provisions of this subpart are applicable...

18 CFR 701.200 - Statement of policy.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 18 Conservation of Power and Water Resources 2 2013-04-01 2012-04-01 true Statement of policy. 701.200 Section 701.200 Conservation of Power and Water Resources WATER RESOURCES COUNCIL COUNCIL ORGANIZATION Availability of Information § 701.200 Statement of policy. Water Resources Council records and...

18 CFR 701.200 - Statement of policy.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 18 Conservation of Power and Water Resources 2 2011-04-01 2011-04-01 false Statement of policy. 701.200 Section 701.200 Conservation of Power and Water Resources WATER RESOURCES COUNCIL COUNCIL ORGANIZATION Availability of Information § 701.200 Statement of policy. Water Resources Council records and...

18 CFR 701.200 - Statement of policy.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 18 Conservation of Power and Water Resources 2 2012-04-01 2012-04-01 false Statement of policy. 701.200 Section 701.200 Conservation of Power and Water Resources WATER RESOURCES COUNCIL COUNCIL ORGANIZATION Availability of Information § 701.200 Statement of policy. Water Resources Council records and...

18 CFR 701.200 - Statement of policy.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 18 Conservation of Power and Water Resources 2 2014-04-01 2014-04-01 false Statement of policy. 701.200 Section 701.200 Conservation of Power and Water Resources WATER RESOURCES COUNCIL COUNCIL ORGANIZATION Availability of Information § 701.200 Statement of policy. Water Resources Council records and...

18 CFR 701.200 - Statement of policy.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Statement of policy. 701.200 Section 701.200 Conservation of Power and Water Resources WATER RESOURCES COUNCIL COUNCIL ORGANIZATION Availability of Information § 701.200 Statement of policy. Water Resources Council records and...

17 CFR 200.57 - Relationships with other members.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Relationships with other members. 200.57 Section 200.57 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION ORGANIZATION; CONDUCT AND ETHICS; AND INFORMATION AND REQUESTS Canons of Ethics § 200.57 Relationships with...

42 CFR 422.200 - Basis and scope.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 3 2010-10-01 2010-10-01 false Basis and scope. 422.200 Section 422.200 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE PROGRAM MEDICARE ADVANTAGE PROGRAM Relationships With Providers § 422.200 Basis and scope. This...

2 CFR 200.82 - Protected Personally Identifiable Information (Protected PII).

Code of Federal Regulations, 2014 CFR

2014-01-01

... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Protected Personally Identifiable Information (Protected PII). 200.82 Section 200.82 Grants and Agreements Office of Management and Budget... § 200.82 Protected Personally Identifiable Information (Protected PII). Protected PII means an...

42 CFR 414.200 - Purpose.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 3 2011-10-01 2011-10-01 false Purpose. 414.200 Section 414.200 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE... Prosthetic and Orthotic Devices § 414.200 Purpose. This subpart implements sections 1834 (a) and (h) of the...

42 CFR 414.200 - Purpose.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 3 2010-10-01 2010-10-01 false Purpose. 414.200 Section 414.200 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE... Prosthetic and Orthotic Devices § 414.200 Purpose. This subpart implements sections 1834 (a) and (h) of the...

2 CFR 200.41 - Federal interest.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Federal interest. 200.41 Section 200.41 Grants and Agreements Office of Management and Budget Guidance for Grants and Agreements OFFICE OF... REQUIREMENTS FOR FEDERAL AWARDS Acronyms and Definitions Acronyms § 200.41 Federal interest. Federal interest...

miR-200 family promotes podocyte differentiation through repression of RSAD2

PubMed Central

Li, Zhigui; Yin, Hongqiang; Hao, Shuang; Wang, Lifeng; Gao, Jing; Tan, Xiaoyue; Yang, Zhuo

2016-01-01

Mature podocytes are highly differentiated cells with several characteristic phenotypic features that are involved in the glomerular filtration function. During kidney development, a series of changes of the morphological characteristics and cellular functions may happen in podocytes. The miR-200 family functions in various biological and pathological processes. But the underlying molecular mechanisms of miR-200 family that functions in podocyte differentiation remain poorly understood. Herein is shown that miR-200a, miR-200b and miR-429 are significantly upregulated during the differentiation of podocytes, with highest upregulation of miR-200a. In these cells, restraint of miR-200 family by RNA interference assay revealed a prominent inhibition of cell differentiation. More intriguingly, miR-200 family directly inhibited the radical S-adenosyl methionine domain-containing protein 2 (RASD2) expression. Moreover, further upregulation of RSAD2 combining with restraint of miR-200 family revealed a promotion of podocyte dedifferentiation and proliferation. In addition, the expression of RSAD2 is consistent with that of in vitro podocyte differentiation in prenatal and postnatal mouse kidney, and significantly down-regulated during the kidney development. Together, these findings indicate that miR-200 family may potentially promote podocyte differentiation through repression of RSAD2 expression. Our data also demonstrate a novel role of the antiviral protein RSAD2 as a regulator in cell differentiation. PMID:27251424

Relationship between early and late stages of information processing: an event-related potential study

PubMed Central

Portella, Claudio; Machado, Sergio; Arias-Carrión, Oscar; Sack, Alexander T.; Silva, Julio Guilherme; Orsini, Marco; Leite, Marco Antonio Araujo; Silva, Adriana Cardoso; Nardi, Antonio E.; Cagy, Mauricio; Piedade, Roberto; Ribeiro, Pedro

2012-01-01

The brain is capable of elaborating and executing different stages of information processing. However, exactly how these stages are processed in the brain remains largely unknown. This study aimed to analyze the possible correlation between early and late stages of information processing by assessing the latency to, and amplitude of, early and late event-related potential (ERP) components, including P200, N200, premotor potential (PMP) and P300, in healthy participants in the context of a visual oddball paradigm. We found a moderate positive correlation among the latency of P200 (electrode O2), N200 (electrode O2), PMP (electrode C3), P300 (electrode PZ) and the reaction time (RT). In addition, moderate negative correlation between the amplitude of P200 and the latencies of N200 (electrode O2), PMP (electrode C3), P300 (electrode PZ) was found. Therefore, we propose that if the secondary processing of visual input (P200 latency) occurs faster, the following will also happen sooner: discrimination and classification process of this input (N200 latency), motor response processing (PMP latency), reorganization of attention and working memory update (P300 latency), and RT. N200, PMP, and P300 latencies are also anticipated when higher activation level of occipital areas involved in the secondary processing of visual input rise (P200 amplitude). PMID:23355929

[Association of methionine synthase reductase gene polymorphism with unexplained recurrent spontaneous abortion].

PubMed

Guo, Qian-nan; Liao, Shi-xiu; Kang, Bing; Zhang, Ju-xin; Wang, Rui-li; Ding, Xue-bing; Zhang, Wei-hua

2012-10-01

To explore the relationship between the polymorphism of methionine synthase reductase (MTRR) A66G and the susceptibility to unexplained repeated spontaneous abortion (URSA). Total of 200 Henan Han couples with URSA (URSA group) and 76 Henan Han healthy couples without URSA (control group) were enrolled in this study. Their MTRR A66G genotypes were determined by PCR restriction fragment length polymorphism (PCR-RFLP). (1) The allele frequencies of MTRR A66G: the frequencies of allele A and allele G in URSA group were 76.5% (153/200) in husband and 72.8% (146/200) in wife, 23.5% (47/200) in husband and 27.2% (54/200) in wife, respectively. The frequencies of allele A and allele G in control group were 78.9% (60/76) in husband and 78.3% (59/76) in wife, 21.1% (16/76) in husband and 21.7% (16/76) in wife, respectively. The frequencies of allele A and allele G were not significantly different between female and male subjects within the same experimental group (P > 0.05), and also there were not significantly different between the same gender subjects at URAS and control groups (P > 0.05). (2) The genotype frequencies of MTRR A66G: the frequencies of genotype AA, AG and GG in URSA group were 57.0% (114/200) in husband and 52.0% (104/200) in wife, 39.0% (78/200) in husband and 41.5% (83/200) in wife, 4.0% (8/200) in husband and 6.5% (13/200) in wife, prepectively. The frequencies of genotype AA, AG and GG in control group were 59.2% (45/76) in husband and 59.2% (50/76) in wife, 39.5% (30/76) in husband and 38.2% (29/76) in wife; 1.3% (1/76) in husband and 2.6% (2/76) in wife, prepectively. The frequencies of genotype AA, AG and GG were not significantly different between female and male subjects within the same group (P > 0.05), and also there were not significantly different between the same gender subjects at URSA and control groups (P > 0.05).(3)Combined genotype of couples: the combined genotype frequencies of GG + GG, GG + AG, GG + AA, AG + AG, AG + AA and AA + AA in URSA group were 1.0% (2/200), 2.5% (5/200), 6.0% (12/200), 20.0% (40/200), 38.0% (76/200), and 32.5% (65/200), prepectively; the combined genotype frequencies in control group were 0, 1.3% (1/76), 2.6% (2/76), 17.1% (13/76), 42.1% (32/76), 36.8% (28/76), prepectively. The combined genotype analysis between the two groups were also not significantly different (P > 0.05). The polymorphism of MTRR A66G gene was not associated with the susceptibility to URSA (P > 0.05), and so it was not the inherited genetic risk factor of URSA.

Distinct roles of autophagy-dependent and -independent functions of FIP200 revealed by generation and analysis of a mutant knock-in mouse model

PubMed Central

Chen, Song; Wang, Chenran; Yeo, Syn; Liang, Chun-Chi; Okamoto, Takako; Sun, Shaogang; Wen, Jian; Guan, Jun-Lin

2016-01-01

Autophagy is an evolutionarily conserved cellular process controlled through a set of essential autophagy genes (Atgs). However, there is increasing evidence that most, if not all, Atgs also possess functions independent of their requirement in canonical autophagy, making it difficult to distinguish the contributions of autophagy-dependent or -independent functions of a particular Atg to various biological processes. To distinguish these functions for FIP200 (FAK family-interacting protein of 200 kDa), an Atg in autophagy induction, we examined FIP200 interaction with its autophagy partner, Atg13. We found that residues 582–585 (LQFL) in FIP200 are required for interaction with Atg13, and mutation of these residues to AAAA (designated the FIP200-4A mutant) abolished its canonical autophagy function in vitro. Furthermore, we created a FIP200-4A mutant knock-in mouse model and found that specifically blocking FIP200 interaction with Atg13 abolishes autophagy in vivo, providing direct support for the essential role of the ULK1/Atg13/FIP200/Atg101 complex in the process beyond previous studies relying on the complete knockout of individual components. Analysis of the new mouse model showed that nonautophagic functions of FIP200 are sufficient to fully support embryogenesis by maintaining a protective role in TNFα-induced apoptosis. However, FIP200-mediated canonical autophagy is required to support neonatal survival and tumor cell growth. These studies provide the first genetic evidence linking an Atg's autophagy and nonautophagic functions to different biological processes in vivo. PMID:27013233

20 CFR 200.3 - Obtaining forms from the Railroad Retirement Board.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Obtaining forms from the Railroad Retirement Board. 200.3 Section 200.3 Employees' Benefits RAILROAD RETIREMENT BOARD GENERAL ADMINISTRATION GENERAL ADMINISTRATION § 200.3 Obtaining forms from the Railroad Retirement Board. Forms used by the Board, including...

2 CFR 200.85 - Real property.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Real property. 200.85 Section 200.85 Grants and Agreements Office of Management and Budget Guidance for Grants and Agreements OFFICE OF MANAGEMENT... REQUIREMENTS FOR FEDERAL AWARDS Acronyms and Definitions Acronyms § 200.85 Real property. Real property means...

2 CFR 200.311 - Real property.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Real property. 200.311 Section 200.311... REQUIREMENTS FOR FEDERAL AWARDS Post Federal Award Requirements Property Standards § 200.311 Real property. (a) Title. Subject to the obligations and conditions set forth in this section, title to real property...

49 CFR 200.9 - Hearings.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Hearings. 200.9 Section 200.9 Transportation Other... TRANSPORTATION INFORMAL RULES OF PRACTICE FOR PASSENGER SERVICE § 200.9 Hearings. (a) Pursuant to any application... Administrator. (b) Pursuant to any application under this part, an oral hearing will be held if required by...

24 CFR 291.200 - Future REO acquisition method.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Future REO acquisition method. 291.200 Section 291.200 Housing and Urban Development Regulations Relating to Housing and Urban... Sales Procedures § 291.200 Future REO acquisition method. (a) Under this method of property disposition...

24 CFR 291.200 - Future REO acquisition method.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Future REO acquisition method. 291.200 Section 291.200 Housing and Urban Development Regulations Relating to Housing and Urban... Sales Procedures § 291.200 Future REO acquisition method. (a) Under this method of property disposition...

29 CFR 548.200 - Requirements.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 29 Labor 3 2014-07-01 2014-07-01 false Requirements. 548.200 Section 548.200 Labor Regulations... ESTABLISHED BASIC RATES FOR COMPUTING OVERTIME PAY Interpretations Requirements for A Basic Rate § 548.200 Requirements. The following conditions must be satisfied if a “basic” rate is to be considered proper under...

29 CFR 548.200 - Requirements.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 29 Labor 3 2013-07-01 2013-07-01 false Requirements. 548.200 Section 548.200 Labor Regulations... ESTABLISHED BASIC RATES FOR COMPUTING OVERTIME PAY Interpretations Requirements for A Basic Rate § 548.200 Requirements. The following conditions must be satisfied if a “basic” rate is to be considered proper under...

29 CFR 548.200 - Requirements.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 29 Labor 3 2012-07-01 2012-07-01 false Requirements. 548.200 Section 548.200 Labor Regulations... ESTABLISHED BASIC RATES FOR COMPUTING OVERTIME PAY Interpretations Requirements for A Basic Rate § 548.200 Requirements. The following conditions must be satisfied if a “basic” rate is to be considered proper under...

4 CFR 200.15 - Systems of records covered by exemptions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 4 Accounts 1 2010-01-01 2010-01-01 false Systems of records covered by exemptions. 200.15 Section 200.15 Accounts RECOVERY ACCOUNTABILITY AND TRANSPARENCY BOARD PRIVACY ACT OF 1974 § 200.15 Systems of records covered by exemptions. The Board currently has no exempt systems of records. ...

4 CFR 200.5 - Requests for access to records.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 4 Accounts 1 2010-01-01 2010-01-01 false Requests for access to records. 200.5 Section 200.5 Accounts RECOVERY ACCOUNTABILITY AND TRANSPARENCY BOARD PRIVACY ACT OF 1974 § 200.5 Requests for access to...: Privacy Act Officer, Recovery Accountability and Transparency Board, 1717 Pennsylvania Avenue, NW., Suite...

4 CFR 200.8 - Appealing denials of access.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 4 Accounts 1 2010-01-01 2010-01-01 false Appealing denials of access. 200.8 Section 200.8 Accounts RECOVERY ACCOUNTABILITY AND TRANSPARENCY BOARD PRIVACY ACT OF 1974 § 200.8 Appealing denials of access. (a... writing. The appeal should be directed to Executive Director, Recovery Accountability and Transparency...

4 CFR 200.6 - Processing of requests.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 4 Accounts 1 2010-01-01 2010-01-01 false Processing of requests. 200.6 Section 200.6 Accounts RECOVERY ACCOUNTABILITY AND TRANSPARENCY BOARD PRIVACY ACT OF 1974 § 200.6 Processing of requests. Upon receipt of a request for information, the Privacy Act Officer will ascertain whether the records...

4 CFR 200.9 - Requests for correction of records.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 4 Accounts 1 2010-01-01 2010-01-01 false Requests for correction of records. 200.9 Section 200.9 Accounts RECOVERY ACCOUNTABILITY AND TRANSPARENCY BOARD PRIVACY ACT OF 1974 § 200.9 Requests for correction... Act Officer, Recovery Accountability and Transparency Board, 1717 Pennsylvania Avenue, NW., Suite 700...

17 CFR 200.18 - Director of Division of Corporation Finance.

Code of Federal Regulations, 2012 CFR

2012-04-01

... Corporation Finance. 200.18 Section 200.18 Commodity and Securities Exchanges SECURITIES AND EXCHANGE... General Organization § 200.18 Director of Division of Corporation Finance. The Director of the Division of Corporation Finance is responsible to the Commission for the administration of all matters (except those...

24 CFR 200.83 - Interest rate.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Interest rate. 200.83 Section 200... Eligibility Requirements for Existing Projects Mortgage Provisions § 200.83 Interest rate. (a) The mortgage shall bear interest at the rate agreed upon by the mortgagee and the mortgagor. (b) Interest shall be...

17 CFR 200.735-7 - Negotiation for employment.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Negotiation for employment. 200.735-7 Section 200.735-7 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION... Employees and Former Members and Employees of the Commission § 200.735-7 Negotiation for employment. (a) An...

17 CFR 200.735-7 - Negotiation for employment.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 17 Commodity and Securities Exchanges 3 2014-04-01 2014-04-01 false Negotiation for employment. 200.735-7 Section 200.735-7 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION... Employees and Former Members and Employees of the Commission § 200.735-7 Negotiation for employment. Members...

17 CFR 200.735-7 - Negotiation for employment.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 17 Commodity and Securities Exchanges 2 2012-04-01 2012-04-01 false Negotiation for employment. 200.735-7 Section 200.735-7 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION... Employees and Former Members and Employees of the Commission § 200.735-7 Negotiation for employment. Members...

17 CFR 200.735-7 - Negotiation for employment.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 17 Commodity and Securities Exchanges 2 2013-04-01 2013-04-01 false Negotiation for employment. 200.735-7 Section 200.735-7 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION... Employees and Former Members and Employees of the Commission § 200.735-7 Negotiation for employment. Members...

17 CFR 200.735-7 - Negotiation for employment.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 17 Commodity and Securities Exchanges 2 2011-04-01 2011-04-01 false Negotiation for employment. 200.735-7 Section 200.735-7 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION... Employees and Former Members and Employees of the Commission § 200.735-7 Negotiation for employment. Members...

6 CFR 27.200 - Information regarding security risk for a chemical facility.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 6 Domestic Security 1 2010-01-01 2010-01-01 false Information regarding security risk for a chemical facility. 27.200 Section 27.200 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY CHEMICAL FACILITY ANTI-TERRORISM STANDARDS Chemical Facility Security Program § 27.200 Information...

45 CFR 1230.200 - Agency and legislative liaison.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 4 2010-10-01 2010-10-01 false Agency and legislative liaison. 1230.200 Section 1230.200 Public Welfare Regulations Relating to Public Welfare (Continued) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE NEW RESTRICTIONS ON LOBBYING Activities by Own Employees § 1230.200 Agency and legislative...

45 CFR 93.200 - Agency and legislative liaison.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 1 2010-10-01 2010-10-01 false Agency and legislative liaison. 93.200 Section 93.200 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION NEW RESTRICTIONS ON LOBBYING Activities by Own Employees § 93.200 Agency and legislative liaison. (a) The prohibition on the...

2 CFR 200.2 - Acquisition cost.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Acquisition cost. 200.2 Section 200.2 Grants and Agreements Office of Management and Budget Guidance for Grants and Agreements OFFICE OF MANAGEMENT... REQUIREMENTS FOR FEDERAL AWARDS Acronyms and Definitions Acronyms § 200.2 Acquisition cost. Acquisition cost...

34 CFR 200.62 - Responsibilities for providing services to private school children.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Participation of Eligible Children in Private Schools § 200.62 Responsibilities for providing services to... a basis equitable to the participation of teachers and families of public school children receiving... school children. 200.62 Section 200.62 Education Regulations of the Offices of the Department of...

41 CFR 105-54.200 - Scope of subpart.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 41 Public Contracts and Property Management 3 2013-07-01 2013-07-01 false Scope of subpart. 105-54.200 Section 105-54.200 Public Contracts and Property Management Federal Property Management... Administration 54-ADVISORY COMMITTEE MANAGEMENT 54.2-Establishment of Advisory Committees § 105-54.200 Scope of...

41 CFR 105-54.200 - Scope of subpart.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Scope of subpart. 105-54.200 Section 105-54.200 Public Contracts and Property Management Federal Property Management... Administration 54-ADVISORY COMMITTEE MANAGEMENT 54.2-Establishment of Advisory Committees § 105-54.200 Scope of...

41 CFR 105-54.200 - Scope of subpart.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 41 Public Contracts and Property Management 3 2012-01-01 2012-01-01 false Scope of subpart. 105-54.200 Section 105-54.200 Public Contracts and Property Management Federal Property Management... Administration 54-ADVISORY COMMITTEE MANAGEMENT 54.2-Establishment of Advisory Committees § 105-54.200 Scope of...

41 CFR 105-54.200 - Scope of subpart.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false Scope of subpart. 105-54.200 Section 105-54.200 Public Contracts and Property Management Federal Property Management... Administration 54-ADVISORY COMMITTEE MANAGEMENT 54.2-Establishment of Advisory Committees § 105-54.200 Scope of...

41 CFR 105-54.200 - Scope of subpart.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 41 Public Contracts and Property Management 3 2014-01-01 2014-01-01 false Scope of subpart. 105-54.200 Section 105-54.200 Public Contracts and Property Management Federal Property Management... Administration 54-ADVISORY COMMITTEE MANAGEMENT 54.2-Establishment of Advisory Committees § 105-54.200 Scope of...

23 CFR 200.11 - Procedures for processing Title VI reviews.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 23 Highways 1 2010-04-01 2010-04-01 false Procedures for processing Title VI reviews. 200.11 Section 200.11 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CIVIL RIGHTS TITLE VI PROGRAM AND RELATED STATUTES-IMPLEMENTATION AND REVIEW PROCEDURES § 200.11 Procedures for processing Title...

23 CFR 200.11 - Procedures for processing Title VI reviews.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 23 Highways 1 2014-04-01 2014-04-01 false Procedures for processing Title VI reviews. 200.11 Section 200.11 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CIVIL RIGHTS TITLE VI PROGRAM AND RELATED STATUTES-IMPLEMENTATION AND REVIEW PROCEDURES § 200.11 Procedures for processing Title...

23 CFR 200.11 - Procedures for processing Title VI reviews.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 23 Highways 1 2011-04-01 2011-04-01 false Procedures for processing Title VI reviews. 200.11 Section 200.11 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CIVIL RIGHTS TITLE VI PROGRAM AND RELATED STATUTES-IMPLEMENTATION AND REVIEW PROCEDURES § 200.11 Procedures for processing Title...

23 CFR 200.11 - Procedures for processing Title VI reviews.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 23 Highways 1 2013-04-01 2013-04-01 false Procedures for processing Title VI reviews. 200.11 Section 200.11 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CIVIL RIGHTS TITLE VI PROGRAM AND RELATED STATUTES-IMPLEMENTATION AND REVIEW PROCEDURES § 200.11 Procedures for processing Title...

13 CFR 120.200 - What bonding requirements exist during construction?

Code of Federal Regulations, 2012 CFR

2012-01-01

... 13 Business Credit and Assistance 1 2012-01-01 2012-01-01 false What bonding requirements exist during construction? 120.200 Section 120.200 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION BUSINESS LOANS Policies Specific to 7(a) Loans Bonding Requirements § 120.200 What bonding requirements...

13 CFR 120.200 - What bonding requirements exist during construction?

Code of Federal Regulations, 2011 CFR

2011-01-01

... 13 Business Credit and Assistance 1 2011-01-01 2011-01-01 false What bonding requirements exist during construction? 120.200 Section 120.200 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION BUSINESS LOANS Policies Specific to 7(a) Loans Bonding Requirements § 120.200 What bonding requirements...

13 CFR 120.200 - What bonding requirements exist during construction?

Code of Federal Regulations, 2014 CFR

2014-01-01

... 13 Business Credit and Assistance 1 2014-01-01 2014-01-01 false What bonding requirements exist during construction? 120.200 Section 120.200 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION BUSINESS LOANS Policies Specific to 7(a) Loans Bonding Requirements § 120.200 What bonding requirements...

13 CFR 120.200 - What bonding requirements exist during construction?

Code of Federal Regulations, 2013 CFR

2013-01-01

... 13 Business Credit and Assistance 1 2013-01-01 2013-01-01 false What bonding requirements exist during construction? 120.200 Section 120.200 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION BUSINESS LOANS Policies Specific to 7(a) Loans Bonding Requirements § 120.200 What bonding requirements...

17 CFR 200.20b - Director of Division of Investment Management.

Code of Federal Regulations, 2010 CFR

2010-04-01

... Investment Management. 200.20b Section 200.20b Commodity and Securities Exchanges SECURITIES AND EXCHANGE... General Organization § 200.20b Director of Division of Investment Management. The Director of the Division of Investment Management is responsible to the Commission for the administration of the Commission's...

34 CFR 200.6 - Inclusion of all students.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 34 Education 1 2014-07-01 2014-07-01 false Inclusion of all students. 200.6 Section 200.6 Education Regulations of the Offices of the Department of Education OFFICE OF ELEMENTARY AND SECONDARY... Basic Programs Operated by Local Educational Agencies Standards and Assessments § 200.6 Inclusion of all...

34 CFR 200.6 - Inclusion of all students.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 34 Education 1 2013-07-01 2013-07-01 false Inclusion of all students. 200.6 Section 200.6 Education Regulations of the Offices of the Department of Education OFFICE OF ELEMENTARY AND SECONDARY... Basic Programs Operated by Local Educational Agencies Standards and Assessments § 200.6 Inclusion of all...

34 CFR 200.6 - Inclusion of all students.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 34 Education 1 2012-07-01 2012-07-01 false Inclusion of all students. 200.6 Section 200.6 Education Regulations of the Offices of the Department of Education OFFICE OF ELEMENTARY AND SECONDARY... Basic Programs Operated by Local Educational Agencies Standards and Assessments § 200.6 Inclusion of all...

19 CFR 200.735-104 - Disciplinary and other remedial action.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 19 Customs Duties 3 2010-04-01 2010-04-01 false Disciplinary and other remedial action. 200.735-104 Section 200.735-104 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION EMPLOYEE RESPONSIBILITIES AND CONDUCT General Provisions § 200.735-104 Disciplinary and other remedial action. (a) An...

19 CFR 200.735-104 - Disciplinary and other remedial action.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 19 Customs Duties 3 2012-04-01 2012-04-01 false Disciplinary and other remedial action. 200.735-104 Section 200.735-104 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION EMPLOYEE RESPONSIBILITIES AND CONDUCT General Provisions § 200.735-104 Disciplinary and other remedial action. (a) An...

19 CFR 200.735-104 - Disciplinary and other remedial action.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 19 Customs Duties 3 2014-04-01 2014-04-01 false Disciplinary and other remedial action. 200.735-104 Section 200.735-104 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION EMPLOYEE RESPONSIBILITIES AND CONDUCT General Provisions § 200.735-104 Disciplinary and other remedial action. (a) An...

19 CFR 200.735-104 - Disciplinary and other remedial action.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 19 Customs Duties 3 2013-04-01 2013-04-01 false Disciplinary and other remedial action. 200.735-104 Section 200.735-104 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION EMPLOYEE RESPONSIBILITIES AND CONDUCT General Provisions § 200.735-104 Disciplinary and other remedial action. (a) An...

19 CFR 200.735-104 - Disciplinary and other remedial action.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 19 Customs Duties 3 2011-04-01 2011-04-01 false Disciplinary and other remedial action. 200.735-104 Section 200.735-104 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION EMPLOYEE RESPONSIBILITIES AND CONDUCT General Provisions § 200.735-104 Disciplinary and other remedial action. (a) An...

45 CFR 157.200 - Eligibility of qualified employers to participate in a SHOP.

Code of Federal Regulations, 2012 CFR

2012-10-01

... in a SHOP. 157.200 Section 157.200 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS EMPLOYER INTERACTIONS WITH EXCHANGES AND SHOP PARTICIPATION Standards for Qualified Employers § 157.200 Eligibility of qualified employers to participate in a SHOP. (a...

45 CFR 157.200 - Eligibility of qualified employers to participate in a SHOP.

Code of Federal Regulations, 2013 CFR

2013-10-01

... in a SHOP. 157.200 Section 157.200 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS EMPLOYER INTERACTIONS WITH EXCHANGES AND SHOP PARTICIPATION Standards for Qualified Employers § 157.200 Eligibility of qualified employers to participate in a SHOP. (a...

45 CFR 157.200 - Eligibility of qualified employers to participate in a SHOP.

Code of Federal Regulations, 2014 CFR

2014-10-01

... in a SHOP. 157.200 Section 157.200 Public Welfare Department of Health and Human Services REQUIREMENTS RELATING TO HEALTH CARE ACCESS EMPLOYER INTERACTIONS WITH EXCHANGES AND SHOP PARTICIPATION Standards for Qualified Employers § 157.200 Eligibility of qualified employers to participate in a SHOP. (a...

7 CFR 3015.200 - Acknowledgement of support on publications and audiovisuals.

Code of Federal Regulations, 2010 CFR

2010-01-01

... audiovisuals. 3015.200 Section 3015.200 Agriculture Regulations of the Department of Agriculture (Continued... Miscellaneous § 3015.200 Acknowledgement of support on publications and audiovisuals. (a) Definitions. Appendix A defines “audiovisual,” “production of an audiovisual,” and “publication.” (b) Publications...

17 CFR 200.553 - Draft, final and supplemental impact statements.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 17 Commodity and Securities Exchanges 3 2014-04-01 2014-04-01 false Draft, final and supplemental impact statements. 200.553 Section 200.553 Commodity and Securities Exchanges SECURITIES AND EXCHANGE... Protection of the Environment § 200.553 Draft, final and supplemental impact statements. If the Commission...

17 CFR 200.553 - Draft, final and supplemental impact statements.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 17 Commodity and Securities Exchanges 2 2012-04-01 2012-04-01 false Draft, final and supplemental impact statements. 200.553 Section 200.553 Commodity and Securities Exchanges SECURITIES AND EXCHANGE... Protection of the Environment § 200.553 Draft, final and supplemental impact statements. If the Commission...

17 CFR 200.553 - Draft, final and supplemental impact statements.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 17 Commodity and Securities Exchanges 2 2013-04-01 2013-04-01 false Draft, final and supplemental impact statements. 200.553 Section 200.553 Commodity and Securities Exchanges SECURITIES AND EXCHANGE... Protection of the Environment § 200.553 Draft, final and supplemental impact statements. If the Commission...

17 CFR 200.553 - Draft, final and supplemental impact statements.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 17 Commodity and Securities Exchanges 2 2011-04-01 2011-04-01 false Draft, final and supplemental impact statements. 200.553 Section 200.553 Commodity and Securities Exchanges SECURITIES AND EXCHANGE... Protection of the Environment § 200.553 Draft, final and supplemental impact statements. If the Commission...

2 CFR 200.472 - Training and education costs.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Training and education costs. 200.472 Section 200.472 Grants and Agreements Office of Management and Budget Guidance for Grants and Agreements... Cost § 200.472 Training and education costs. The cost of training and education provided for employee...

24 CFR 200.610 - Policy.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Policy. 200.610 Section 200.610... GENERAL INTRODUCTION TO FHA PROGRAMS Affirmative Fair Housing Marketing Regulations § 200.610 Policy. It is the policy of the Department to administer its FHA housing programs affirmatively, as to achieve a...

40 CFR 246.200-3 - Recommended procedures: Market study.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Recommended procedures: Market study. 246.200-3 Section 246.200-3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... § 246.200-3 Recommended procedures: Market study. An investigation of markets should be made by the...

40 CFR 246.200-3 - Recommended procedures: Market study.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Recommended procedures: Market study. 246.200-3 Section 246.200-3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... § 246.200-3 Recommended procedures: Market study. An investigation of markets should be made by the...

17 CFR 200.18 - Director of Division of Corporation Finance.

Code of Federal Regulations, 2014 CFR

2014-04-01

... Corporation Finance. 200.18 Section 200.18 Commodity and Securities Exchanges SECURITIES AND EXCHANGE... General Organization § 200.18 Director of Division of Corporation Finance. The Director of the Division of Corporation Finance is responsible to the Commission for the administration of all matters (except those...

17 CFR 200.18 - Director of Division of Corporation Finance.

Code of Federal Regulations, 2013 CFR

2013-04-01

... Corporation Finance. 200.18 Section 200.18 Commodity and Securities Exchanges SECURITIES AND EXCHANGE... General Organization § 200.18 Director of Division of Corporation Finance. The Director of the Division of Corporation Finance is responsible to the Commission for the administration of all matters (except those...

17 CFR 200.18 - Director of Division of Corporation Finance.

Code of Federal Regulations, 2010 CFR

2010-04-01

... Corporation Finance. 200.18 Section 200.18 Commodity and Securities Exchanges SECURITIES AND EXCHANGE... General Organization § 200.18 Director of Division of Corporation Finance. The Director of the Division of Corporation Finance is responsible to the Commission for the administration of all matters (except those...

17 CFR 200.26a - Office of Information Technology.

Code of Federal Regulations, 2011 CFR

2011-04-01

... Organization § 200.26a Office of Information Technology. The Office of Information Technology is responsible... 17 Commodity and Securities Exchanges 2 2011-04-01 2011-04-01 false Office of Information Technology. 200.26a Section 200.26a Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION...

17 CFR 200.26a - Office of Information Technology.

Code of Federal Regulations, 2014 CFR

2014-04-01

... Organization § 200.26a Office of Information Technology. The Office of Information Technology is responsible... 17 Commodity and Securities Exchanges 3 2014-04-01 2014-04-01 false Office of Information Technology. 200.26a Section 200.26a Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION...

17 CFR 200.26a - Office of Information Technology.

Code of Federal Regulations, 2013 CFR

2013-04-01

... Organization § 200.26a Office of Information Technology. The Office of Information Technology is responsible... 17 Commodity and Securities Exchanges 2 2013-04-01 2013-04-01 false Office of Information Technology. 200.26a Section 200.26a Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION...

17 CFR 200.26a - Office of Information Technology.

Code of Federal Regulations, 2012 CFR

2012-04-01

... Organization § 200.26a Office of Information Technology. The Office of Information Technology is responsible... 17 Commodity and Securities Exchanges 2 2012-04-01 2012-04-01 false Office of Information Technology. 200.26a Section 200.26a Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION...

41 CFR 301-71.200 - Who must review and sign travel claims?

Code of Federal Regulations, 2010 CFR

2010-07-01

... travel claims? 301-71.200 Section 301-71.200 Public Contracts and Property Management Federal Travel Regulation System TEMPORARY DUTY (TDY) TRAVEL ALLOWANCES AGENCY RESPONSIBILITIES 71-AGENCY TRAVEL ACCOUNTABILITY REQUIREMENTS Travel Claims for Reimbursement § 301-71.200 Who must review and sign travel claims...

24 CFR 200.926b - Model codes.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Model codes. 200.926b Section 200... DEVELOPMENT GENERAL INTRODUCTION TO FHA PROGRAMS Minimum Property Standards § 200.926b Model codes. (a) Incorporation by reference. The following model code publications are incorporated by reference in accordance...

42 CFR 400.200 - General definitions.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 42 Public Health 2 2013-10-01 2013-10-01 false General definitions. 400.200 Section 400.200 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS INTRODUCTION; DEFINITIONS Definitions § 400.200 General definitions. In this chapter, unless the context indicates otherwise— Act means the...

42 CFR 400.200 - General definitions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 2 2010-10-01 2010-10-01 false General definitions. 400.200 Section 400.200 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS INTRODUCTION; DEFINITIONS Definitions § 400.200 General definitions. In this chapter, unless the context indicates otherwise— Act means the...

42 CFR 400.200 - General definitions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 2 2011-10-01 2011-10-01 false General definitions. 400.200 Section 400.200 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS INTRODUCTION; DEFINITIONS Definitions § 400.200 General definitions. In this chapter, unless the context indicates otherwise— Act means the...

42 CFR 400.200 - General definitions.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 2 2014-10-01 2014-10-01 false General definitions. 400.200 Section 400.200 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS INTRODUCTION; DEFINITIONS Definitions § 400.200 General definitions. In this chapter, unless the context indicates otherwise— Act means the...

42 CFR 400.200 - General definitions.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 42 Public Health 2 2012-10-01 2012-10-01 false General definitions. 400.200 Section 400.200 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS INTRODUCTION; DEFINITIONS Definitions § 400.200 General definitions. In this chapter, unless the context indicates otherwise— Act means the...

24 CFR 200.83 - Interest rate.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Interest rate. 200.83 Section 200... Eligibility Requirements for Existing Projects Mortgage Provisions § 200.83 Interest rate. (a) The mortgage shall bear interest at the rate agreed upon by the mortgagee and the mortgagor. (b) Interest shall be...

7 CFR 930.200 - Assessment rate.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 8 2011-01-01 2011-01-01 false Assessment rate. 930.200 Section 930.200 Agriculture... MICHIGAN, NEW YORK, PENNSYLVANIA, OREGON, UTAH, WASHINGTON, AND WISCONSIN Assessment Rates § 930.200 Assessment rate. On and after October 1, 2010, the assessment rate imposed on handlers shall be $0.0075 per...

24 CFR 200.83 - Interest rate.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Interest rate. 200.83 Section 200... Eligibility Requirements for Existing Projects Mortgage Provisions § 200.83 Interest rate. (a) The mortgage shall bear interest at the rate agreed upon by the mortgagee and the mortgagor. (b) Interest shall be...

24 CFR 200.83 - Interest rate.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 2 2013-04-01 2013-04-01 false Interest rate. 200.83 Section 200... Eligibility Requirements for Existing Projects Mortgage Provisions § 200.83 Interest rate. (a) The mortgage shall bear interest at the rate agreed upon by the mortgagee and the mortgagor. (b) Interest shall be...

7 CFR 930.200 - Assessment rate.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 8 2012-01-01 2012-01-01 false Assessment rate. 930.200 Section 930.200 Agriculture... MICHIGAN, NEW YORK, PENNSYLVANIA, OREGON, UTAH, WASHINGTON, AND WISCONSIN Assessment Rates § 930.200 Assessment rate. On and after October 1, 2010, the assessment rate imposed on handlers shall be $0.0075 per...

24 CFR 200.83 - Interest rate.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Interest rate. 200.83 Section 200... Eligibility Requirements for Existing Projects Mortgage Provisions § 200.83 Interest rate. (a) The mortgage shall bear interest at the rate agreed upon by the mortgagee and the mortgagor. (b) Interest shall be...

7 CFR 930.200 - Assessment rate.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 8 2014-01-01 2014-01-01 false Assessment rate. 930.200 Section 930.200 Agriculture... MICHIGAN, NEW YORK, PENNSYLVANIA, OREGON, UTAH, WASHINGTON, AND WISCONSIN Assessment Rates § 930.200 Assessment rate. On and after October 1, 2010, the assessment rate imposed on handlers shall be $0.0075 per...

20 CFR 61.200 - Entitlement to benefits.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 20 Employees' Benefits 1 2013-04-01 2012-04-01 true Entitlement to benefits. 61.200 Section 61.200 Employees' Benefits OFFICE OF WORKERS' COMPENSATION PROGRAMS, DEPARTMENT OF LABOR COMPENSATION FOR INJURY... § 61.200 Entitlement to benefits. (a) Compensation under section 101(a) of the Act is payable for...

20 CFR 61.200 - Entitlement to benefits.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 20 Employees' Benefits 1 2011-04-01 2011-04-01 false Entitlement to benefits. 61.200 Section 61.200 Employees' Benefits OFFICE OF WORKERS' COMPENSATION PROGRAMS, DEPARTMENT OF LABOR COMPENSATION FOR..., Disability or Death § 61.200 Entitlement to benefits. (a) Compensation under section 101(a) of the Act is...

20 CFR 61.200 - Entitlement to benefits.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 20 Employees' Benefits 1 2014-04-01 2012-04-01 true Entitlement to benefits. 61.200 Section 61.200 Employees' Benefits OFFICE OF WORKERS' COMPENSATION PROGRAMS, DEPARTMENT OF LABOR COMPENSATION FOR INJURY... § 61.200 Entitlement to benefits. (a) Compensation under section 101(a) of the Act is payable for...

20 CFR 61.200 - Entitlement to benefits.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 20 Employees' Benefits 1 2012-04-01 2012-04-01 false Entitlement to benefits. 61.200 Section 61.200 Employees' Benefits OFFICE OF WORKERS' COMPENSATION PROGRAMS, DEPARTMENT OF LABOR COMPENSATION FOR..., Disability or Death § 61.200 Entitlement to benefits. (a) Compensation under section 101(a) of the Act is...

24 CFR 200.33 - Labor standards

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Labor standards 200.33 Section 200... Eligibility Requirements for Existing Projects Miscellaneous Cross Cutting Regulations § 200.33 Labor standards (a) The requirements set forth in 29 CFR parts 1, 3 and 5 for compliance with labor standards laws...

7 CFR 930.200 - Assessment rate.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 8 2013-01-01 2013-01-01 false Assessment rate. 930.200 Section 930.200 Agriculture... MICHIGAN, NEW YORK, PENNSYLVANIA, OREGON, UTAH, WASHINGTON, AND WISCONSIN Assessment Rates § 930.200 Assessment rate. On and after October 1, 2010, the assessment rate imposed on handlers shall be $0.0075 per...

46 CFR 183.200 - General design, installation, and maintenance requirements.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 7 2012-10-01 2012-10-01 false General design, installation, and maintenance requirements. 183.200 Section 183.200 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) ELECTRICAL INSTALLATION General Requirements § 183.200 General design, installation, and maintenance...

46 CFR 129.200 - Design, installation, and maintenance.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 4 2014-10-01 2014-10-01 false Design, installation, and maintenance. 129.200 Section 129.200 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS ELECTRICAL INSTALLATIONS General Requirements § 129.200 Design, installation, and maintenance. Electrical equipment on a vessel must be designed,...

46 CFR 183.200 - General design, installation, and maintenance requirements.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 7 2010-10-01 2010-10-01 false General design, installation, and maintenance requirements. 183.200 Section 183.200 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) ELECTRICAL INSTALLATION General Requirements § 183.200 General design, installation, and maintenance...

46 CFR 183.200 - General design, installation, and maintenance requirements.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 7 2013-10-01 2013-10-01 false General design, installation, and maintenance requirements. 183.200 Section 183.200 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) ELECTRICAL INSTALLATION General Requirements § 183.200 General design, installation, and maintenance...

46 CFR 183.200 - General design, installation, and maintenance requirements.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 7 2014-10-01 2014-10-01 false General design, installation, and maintenance requirements. 183.200 Section 183.200 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) ELECTRICAL INSTALLATION General Requirements § 183.200 General design, installation, and maintenance...

46 CFR 129.200 - Design, installation, and maintenance.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 4 2012-10-01 2012-10-01 false Design, installation, and maintenance. 129.200 Section 129.200 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS ELECTRICAL INSTALLATIONS General Requirements § 129.200 Design, installation, and maintenance. Electrical equipment on a vessel must be designed,...

24 CFR 200.192 - Removal of 203(k) consultant.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Removal of 203(k) consultant. 200.192 Section 200.192 Housing and Urban Development Regulations Relating to Housing and Urban... Participation in FHA Programs Section 203(k) Rehabilitation Loan Consultants § 200.192 Removal of 203(k...

24 CFR 200.192 - Removal of 203(k) consultant.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Removal of 203(k) consultant. 200.192 Section 200.192 Housing and Urban Development Regulations Relating to Housing and Urban... Participation in FHA Programs Section 203(k) Rehabilitation Loan Consultants § 200.192 Removal of 203(k...

24 CFR 200.192 - Removal of 203(k) consultant.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Removal of 203(k) consultant. 200.192 Section 200.192 Housing and Urban Development Regulations Relating to Housing and Urban... Participation in FHA Programs Section 203(k) Rehabilitation Loan Consultants § 200.192 Removal of 203(k...

24 CFR 200.192 - Removal of 203(k) consultant.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Removal of 203(k) consultant. 200.192 Section 200.192 Housing and Urban Development Regulations Relating to Housing and Urban... Participation in FHA Programs Section 203(k) Rehabilitation Loan Consultants § 200.192 Removal of 203(k...

24 CFR 200.192 - Removal of 203(k) consultant.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 2 2013-04-01 2013-04-01 false Removal of 203(k) consultant. 200.192 Section 200.192 Housing and Urban Development Regulations Relating to Housing and Urban... Participation in FHA Programs Section 203(k) Rehabilitation Loan Consultants § 200.192 Removal of 203(k...

49 CFR 200.9 - Hearings.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Hearings. 200.9 Section 200.9 Transportation Other... TRANSPORTATION INFORMAL RULES OF PRACTICE FOR PASSENGER SERVICE § 200.9 Hearings. (a) Pursuant to any application... Administrator. (b) Pursuant to any application under this part, an oral hearing will be held if required by...

9 CFR 590.200 - Records and related requirements.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Records and related requirements. 590.200 Section 590.200 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF... and Related Requirements for Eggs and Egg Products Handlers and Related Industries § 590.200 Records...

20 CFR 200.6 - Open meetings.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 20 Employees' Benefits 1 2012-04-01 2012-04-01 false Open meetings. 200.6 Section 200.6 Employees' Benefits RAILROAD RETIREMENT BOARD GENERAL ADMINISTRATION GENERAL ADMINISTRATION § 200.6 Open meetings. (a... meeting, or any change in the scheduling, agenda, or the open or closed status of a meeting; or (ii...

20 CFR 200.6 - Open meetings.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 20 Employees' Benefits 1 2011-04-01 2011-04-01 false Open meetings. 200.6 Section 200.6 Employees' Benefits RAILROAD RETIREMENT BOARD GENERAL ADMINISTRATION GENERAL ADMINISTRATION § 200.6 Open meetings. (a... meeting, or any change in the scheduling, agenda, or the open or closed status of a meeting; or (ii...

20 CFR 200.6 - Open meetings.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Open meetings. 200.6 Section 200.6 Employees' Benefits RAILROAD RETIREMENT BOARD GENERAL ADMINISTRATION GENERAL ADMINISTRATION § 200.6 Open meetings. (a... meeting, or any change in the scheduling, agenda, or the open or closed status of a meeting; or (ii...

20 CFR 200.6 - Open meetings.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 20 Employees' Benefits 1 2013-04-01 2012-04-01 true Open meetings. 200.6 Section 200.6 Employees' Benefits RAILROAD RETIREMENT BOARD GENERAL ADMINISTRATION GENERAL ADMINISTRATION § 200.6 Open meetings. (a... meeting, or any change in the scheduling, agenda, or the open or closed status of a meeting; or (ii...

20 CFR 200.6 - Open meetings.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 20 Employees' Benefits 1 2014-04-01 2012-04-01 true Open meetings. 200.6 Section 200.6 Employees' Benefits RAILROAD RETIREMENT BOARD GENERAL ADMINISTRATION GENERAL ADMINISTRATION § 200.6 Open meetings. (a... meeting, or any change in the scheduling, agenda, or the open or closed status of a meeting; or (ii...

17 CFR 200.735-2 - Policy.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Policy. 200.735-2 Section 200.735-2 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION ORGANIZATION; CONDUCT AND... Members and Employees of the Commission § 200.735-2 Policy. (a) The Securities and Exchange Commission has...

2 CFR 200.64 - Local government.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Local government. 200.64 Section 200.64... REQUIREMENTS FOR FEDERAL AWARDS Acronyms and Definitions Acronyms § 200.64 Local government. Local government means any unit of government within a state, including a: (a) County; (b) Borough; (c) Municipality; (d...

2 CFR 200.303 - Internal controls.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Internal controls. 200.303 Section 200.303... § 200.303 Internal controls. The non-Federal entity must: (a) Establish and maintain effective internal control over the Federal award that provides reasonable assurance that the non-Federal entity is managing...

17 CFR 200.41 - Quorum of the Commission.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Quorum of the Commission. 200.41 Section 200.41 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION ORGANIZATION; CONDUCT AND ETHICS; AND INFORMATION AND REQUESTS Disposition of Commission Business § 200.41 Quorum of the...

17 CFR 200.40 - Joint disposition of business by Commission meeting.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Joint disposition of business by Commission meeting. 200.40 Section 200.40 Commodity and Securities Exchanges SECURITIES AND... Commission Business § 200.40 Joint disposition of business by Commission meeting. Any meeting of the...

17 CFR 200.42 - Disposition of business by seriatim Commission consideration.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Disposition of business by seriatim Commission consideration. 200.42 Section 200.42 Commodity and Securities Exchanges SECURITIES AND... Commission Business § 200.42 Disposition of business by seriatim Commission consideration. (a) Whenever the...

20 CFR 637.200 - Allotments to States.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Allotments to States. 637.200 Section 637.200 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR PROGRAMS UNDER TITLE V OF THE JOB TRAINING PARTNERSHIP ACT Program Planning and Operation § 637.200 Allotments to States. (a...

30 CFR 217.200 - Audits.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Audits. 217.200 Section 217.200 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE MANAGEMENT AUDITS AND INSPECTIONS Coal § 217.200 Audits. An audit of the accounts and books of operators/lessees for the purpose of...

4 CFR 200.13 - Privacy Act training.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 4 Accounts 1 2014-01-01 2013-01-01 true Privacy Act training. 200.13 Section 200.13 Accounts RECOVERY ACCOUNTABILITY AND TRANSPARENCY BOARD PRIVACY ACT OF 1974 § 200.13 Privacy Act training. (a) The... any Board systems of records are informed of all requirements necessary to protect the privacy of...

4 CFR 200.4 - Privacy Act inquiries.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 4 Accounts 1 2013-01-01 2013-01-01 false Privacy Act inquiries. 200.4 Section 200.4 Accounts RECOVERY ACCOUNTABILITY AND TRANSPARENCY BOARD PRIVACY ACT OF 1974 § 200.4 Privacy Act inquiries. (a... Avenue, NW., Suite 700, Washington, DC 20006. Inquiries should be marked “Privacy Act Inquiry” on each...

4 CFR 200.4 - Privacy Act inquiries.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 4 Accounts 1 2014-01-01 2013-01-01 true Privacy Act inquiries. 200.4 Section 200.4 Accounts RECOVERY ACCOUNTABILITY AND TRANSPARENCY BOARD PRIVACY ACT OF 1974 § 200.4 Privacy Act inquiries. (a... Avenue, NW., Suite 700, Washington, DC 20006. Inquiries should be marked “Privacy Act Inquiry” on each...

4 CFR 200.13 - Privacy Act training.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 4 Accounts 1 2012-01-01 2012-01-01 false Privacy Act training. 200.13 Section 200.13 Accounts RECOVERY ACCOUNTABILITY AND TRANSPARENCY BOARD PRIVACY ACT OF 1974 § 200.13 Privacy Act training. (a) The... any Board systems of records are informed of all requirements necessary to protect the privacy of...

4 CFR 200.13 - Privacy Act training.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 4 Accounts 1 2013-01-01 2013-01-01 false Privacy Act training. 200.13 Section 200.13 Accounts RECOVERY ACCOUNTABILITY AND TRANSPARENCY BOARD PRIVACY ACT OF 1974 § 200.13 Privacy Act training. (a) The... any Board systems of records are informed of all requirements necessary to protect the privacy of...

4 CFR 200.13 - Privacy Act training.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 4 Accounts 1 2011-01-01 2011-01-01 false Privacy Act training. 200.13 Section 200.13 Accounts RECOVERY ACCOUNTABILITY AND TRANSPARENCY BOARD PRIVACY ACT OF 1974 § 200.13 Privacy Act training. (a) The... any Board systems of records are informed of all requirements necessary to protect the privacy of...

4 CFR 200.4 - Privacy Act inquiries.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 4 Accounts 1 2012-01-01 2012-01-01 false Privacy Act inquiries. 200.4 Section 200.4 Accounts RECOVERY ACCOUNTABILITY AND TRANSPARENCY BOARD PRIVACY ACT OF 1974 § 200.4 Privacy Act inquiries. (a... Avenue, NW., Suite 700, Washington, DC 20006. Inquiries should be marked “Privacy Act Inquiry” on each...

4 CFR 200.4 - Privacy Act inquiries.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 4 Accounts 1 2011-01-01 2011-01-01 false Privacy Act inquiries. 200.4 Section 200.4 Accounts RECOVERY ACCOUNTABILITY AND TRANSPARENCY BOARD PRIVACY ACT OF 1974 § 200.4 Privacy Act inquiries. (a... Avenue, NW., Suite 700, Washington, DC 20006. Inquiries should be marked “Privacy Act Inquiry” on each...

37 CFR 2.200 - Assignment records open to public inspection.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 37 Patents, Trademarks, and Copyrights 1 2013-07-01 2013-07-01 false Assignment records open to public inspection. 2.200 Section 2.200 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND... the Patent and Trademark Office § 2.200 Assignment records open to public inspection. (a)(1) Separate...

37 CFR 2.200 - Assignment records open to public inspection.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 37 Patents, Trademarks, and Copyrights 1 2014-07-01 2014-07-01 false Assignment records open to public inspection. 2.200 Section 2.200 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND... the Patent and Trademark Office § 2.200 Assignment records open to public inspection. (a)(1) Separate...

37 CFR 2.200 - Assignment records open to public inspection.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 37 Patents, Trademarks, and Copyrights 1 2011-07-01 2011-07-01 false Assignment records open to public inspection. 2.200 Section 2.200 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND... the Patent and Trademark Office § 2.200 Assignment records open to public inspection. (a)(1) Separate...

37 CFR 2.200 - Assignment records open to public inspection.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Assignment records open to public inspection. 2.200 Section 2.200 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND... the Patent and Trademark Office § 2.200 Assignment records open to public inspection. (a)(1) Separate...

20 CFR 645.200 - What does this subpart cover?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false What does this subpart cover? 645.200 Section 645.200 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR PROVISIONS GOVERNING WELFARE-TO-WORK GRANTS General Program and Administrative Requirements § 645.200 What does this...

36 CFR 200.6 - Information available; inspection, copying, and charges.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 36 Parks, Forests, and Public Property 2 2014-07-01 2014-07-01 false Information available; inspection, copying, and charges. 200.6 Section 200.6 Parks, Forests, and Public Property FOREST SERVICE... and 200.2. Forest Service personnel at these offices will assist members of the public seeking Forest...

4 CFR 200.4 - Privacy Act inquiries.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 4 Accounts 1 2010-01-01 2010-01-01 false Privacy Act inquiries. 200.4 Section 200.4 Accounts RECOVERY ACCOUNTABILITY AND TRANSPARENCY BOARD PRIVACY ACT OF 1974 § 200.4 Privacy Act inquiries. (a... Avenue, NW., Suite 700, Washington, DC 20006. Inquiries should be marked “Privacy Act Inquiry” on each...

4 CFR 200.13 - Privacy Act training.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 4 Accounts 1 2010-01-01 2010-01-01 false Privacy Act training. 200.13 Section 200.13 Accounts RECOVERY ACCOUNTABILITY AND TRANSPARENCY BOARD PRIVACY ACT OF 1974 § 200.13 Privacy Act training. (a) The... any Board systems of records are informed of all requirements necessary to protect the privacy of...

50 CFR 665.200 - Hawaii bottomfish and seamount groundfish fisheries. [Reserved

Code of Federal Regulations, 2010 CFR

2010-10-01

... 50 Wildlife and Fisheries 9 2010-10-01 2010-10-01 false Hawaii bottomfish and seamount groundfish fisheries. [Reserved] 665.200 Section 665.200 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT... WESTERN PACIFIC Hawaii Fisheries § 665.200 Hawaii bottomfish and seamount groundfish fisheries. [Reserved] ...

17 CFR 200.553 - Draft, final and supplemental impact statements.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Draft, final and supplemental impact statements. 200.553 Section 200.553 Commodity and Securities Exchanges SECURITIES AND EXCHANGE... Protection of the Environment § 200.553 Draft, final and supplemental impact statements. If the Commission...

46 CFR 184.200 - General.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 7 2010-10-01 2010-10-01 false General. 184.200 Section 184.200 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) VESSEL CONTROL AND MISCELLANEOUS SYSTEMS AND EQUIPMENT Cooking and Heating § 184.200 General. Cooking and heating equipment must be...

9 CFR 113.200 - General requirements for killed virus vaccines.

Code of Federal Regulations, 2014 CFR

2014-01-01

... vaccines. 113.200 Section 113.200 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE... REQUIREMENTS Killed Virus Vaccines § 113.200 General requirements for killed virus vaccines. When prescribed in an applicable Standard Requirement or in the filed Outline of Production, a killed virus vaccine...

9 CFR 113.200 - General requirements for killed virus vaccines.

Code of Federal Regulations, 2013 CFR

2013-01-01

... vaccines. 113.200 Section 113.200 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE... REQUIREMENTS Killed Virus Vaccines § 113.200 General requirements for killed virus vaccines. When prescribed in an applicable Standard Requirement or in the filed Outline of Production, a killed virus vaccine...

9 CFR 113.200 - General requirements for killed virus vaccines.

Code of Federal Regulations, 2011 CFR

2011-01-01

... vaccines. 113.200 Section 113.200 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE... REQUIREMENTS Killed Virus Vaccines § 113.200 General requirements for killed virus vaccines. When prescribed in an applicable Standard Requirement or in the filed Outline of Production, a killed virus vaccine...

9 CFR 113.200 - General requirements for killed virus vaccines.

Code of Federal Regulations, 2012 CFR

2012-01-01

... vaccines. 113.200 Section 113.200 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE... REQUIREMENTS Killed Virus Vaccines § 113.200 General requirements for killed virus vaccines. When prescribed in an applicable Standard Requirement or in the filed Outline of Production, a killed virus vaccine...

24 CFR 200.948 - Building product standards and certification program for carpet cushion.

Code of Federal Regulations, 2010 CFR

2010-04-01

... Minimum Property Standards § 200.948 Building product standards and certification program for carpet... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Building product standards and certification program for carpet cushion. 200.948 Section 200.948 Housing and Urban Development Regulations...

50 CFR 300.200 - Purpose and scope.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 50 Wildlife and Fisheries 9 2011-10-01 2011-10-01 false Purpose and scope. 300.200 Section 300.200... Identification and Certification of Nations § 300.200 Purpose and scope. The purpose of this subpart is to implement the requirements in the High Seas Driftnet Fishing Moratorium Protection Act (“Moratorium...

7 CFR 2.200 - Deputy Chief Information Officer.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 1 2010-01-01 2010-01-01 false Deputy Chief Information Officer. 2.200 Section 2.200... AND GENERAL OFFICERS OF THE DEPARTMENT Delegations of Authority by the Chief Information Officer § 2.200 Deputy Chief Information Officer. Pursuant to § 2.37, the following delegation of authority is...

2 CFR 200.457 - Plant and security costs.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Plant and security costs. 200.457 Section... Cost § 200.457 Plant and security costs. Necessary and reasonable expenses incurred for routine and.... Capital expenditures for plant security purposes are subject to § 200.439 Equipment and other capital...

15 CFR 200.112 - Reports.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 15 Commerce and Foreign Trade 1 2013-01-01 2013-01-01 false Reports. 200.112 Section 200.112... FEES § 200.112 Reports. (a) Results of calibrations and other tests are issued to the customer as formal reports entitled, “National Institute of Standards & Technology Report of Calibration,” “National...

15 CFR 200.112 - Reports.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 15 Commerce and Foreign Trade 1 2011-01-01 2011-01-01 false Reports. 200.112 Section 200.112... FEES § 200.112 Reports. (a) Results of calibrations and other tests are issued to the customer as formal reports entitled, “National Institute of Standards & Technology Report of Calibration,” “National...

15 CFR 200.112 - Reports.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 15 Commerce and Foreign Trade 1 2014-01-01 2014-01-01 false Reports. 200.112 Section 200.112... FEES § 200.112 Reports. (a) Results of calibrations and other tests are issued to the customer as formal reports entitled, “National Institute of Standards & Technology Report of Calibration,” “National...

24 CFR 200.1535 - MAP Lender Review Board.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 2 2013-04-01 2013-04-01 false MAP Lender Review Board. 200.1535 Section 200.1535 Housing and Urban Development Regulations Relating to Housing and Urban Development... Lender Quality Assurance Enforcement § 200.1535 MAP Lender Review Board. (a) Authority—(1) Sanctions. The...

24 CFR 200.1535 - MAP Lender Review Board.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false MAP Lender Review Board. 200.1535 Section 200.1535 Housing and Urban Development Regulations Relating to Housing and Urban Development... Lender Quality Assurance Enforcement § 200.1535 MAP Lender Review Board. (a) Authority—(1) Sanctions. The...

24 CFR 200.1535 - MAP Lender Review Board.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false MAP Lender Review Board. 200.1535 Section 200.1535 Housing and Urban Development Regulations Relating to Housing and Urban Development... Lender Quality Assurance Enforcement § 200.1535 MAP Lender Review Board. (a) Authority—(1) Sanctions. The...

24 CFR 200.1535 - MAP Lender Review Board.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false MAP Lender Review Board. 200.1535 Section 200.1535 Housing and Urban Development Regulations Relating to Housing and Urban Development... Lender Quality Assurance Enforcement § 200.1535 MAP Lender Review Board. (a) Authority—(1) Sanctions. The...

13 CFR 108.200 - Adequate capital for NMVC Companies.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Adequate capital for NMVC Companies. 108.200 Section 108.200 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION NEW MARKETS VENTURE CAPITAL (âNMVCâ) PROGRAM Qualifications for the NMVC Program Capitalizing A Nmvc Company § 108.200...

24 CFR 3.200 - Application.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Application. 3.200 Section 3.200 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development... Coverage § 3.200 Application. Except as provided in §§ 3.205 through 3.235(a), these Title IX regulations...

45 CFR 2555.200 - Application.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 4 2010-10-01 2010-10-01 false Application. 2555.200 Section 2555.200 Public Welfare Regulations Relating to Public Welfare (Continued) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE... Coverage § 2555.200 Application. Except as provided in §§ 2555.205 through 2555.235(a), these Title IX...

33 CFR 167.200 - In the approaches to Chesapeake Bay Traffic Separation Scheme: General.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Bay Traffic Separation Scheme: General. 167.200 Section 167.200 Navigation and Navigable Waters COAST... SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Atlantic East Coast § 167.200 In the approaches to Chesapeake Bay Traffic Separation Scheme: General. (a) The traffic...

33 CFR 167.200 - In the approaches to Chesapeake Bay Traffic Separation Scheme: General.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Bay Traffic Separation Scheme: General. 167.200 Section 167.200 Navigation and Navigable Waters COAST... SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Atlantic East Coast § 167.200 In the approaches to Chesapeake Bay Traffic Separation Scheme: General. (a) The traffic...

34 CFR 200.12 - Single State accountability system.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 34 Education 1 2010-07-01 2010-07-01 false Single State accountability system. 200.12 Section 200... Improving Basic Programs Operated by Local Educational Agencies State Accountability System § 200.12 Single State accountability system. (a)(1) Each State must demonstrate in its State plan that the State has...

33 CFR 167.200 - In the approaches to Chesapeake Bay Traffic Separation Scheme: General.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Bay Traffic Separation Scheme: General. 167.200 Section 167.200 Navigation and Navigable Waters COAST... SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Atlantic East Coast § 167.200 In the approaches to Chesapeake Bay Traffic Separation Scheme: General. (a) The traffic...

33 CFR 167.200 - In the approaches to Chesapeake Bay Traffic Separation Scheme: General.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Bay Traffic Separation Scheme: General. 167.200 Section 167.200 Navigation and Navigable Waters COAST... SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Atlantic East Coast § 167.200 In the approaches to Chesapeake Bay Traffic Separation Scheme: General. (a) The traffic...

33 CFR 167.200 - In the approaches to Chesapeake Bay Traffic Separation Scheme: General.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Bay Traffic Separation Scheme: General. 167.200 Section 167.200 Navigation and Navigable Waters COAST... SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Atlantic East Coast § 167.200 In the approaches to Chesapeake Bay Traffic Separation Scheme: General. (a) The traffic...

17 CFR 200.26a - Office of Information Technology.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Office of Information Technology. 200.26a Section 200.26a Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION... Organization § 200.26a Office of Information Technology. The Office of Information Technology is responsible...

42 CFR 93.200 - Administrative action.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 1 2011-10-01 2011-10-01 false Administrative action. 93.200 Section 93.200 Public... MISCONDUCT Definitions § 93.200 Administrative action. Administrative action means— (a) An HHS action in... related to that research or research training and to conserve public funds; or (b) An HHS action in...

34 CFR 200.42 - Corrective action.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 34 Education 1 2011-07-01 2011-07-01 false Corrective action. 200.42 Section 200.42 Education... Programs Operated by Local Educational Agencies Lea and School Improvement § 200.42 Corrective action. (a) Definition. “Corrective action” means action by an LEA that— (1) Substantially and directly responds to— (i...

34 CFR 200.42 - Corrective action.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 34 Education 1 2010-07-01 2010-07-01 false Corrective action. 200.42 Section 200.42 Education... Programs Operated by Local Educational Agencies Lea and School Improvement § 200.42 Corrective action. (a) Definition. “Corrective action” means action by an LEA that— (1) Substantially and directly responds to— (i...

34 CFR 200.12 - Single State accountability system.

Code of Federal Regulations, 2012 CFR

2012-07-01

... SECONDARY EDUCATION, DEPARTMENT OF EDUCATION TITLE I-IMPROVING THE ACADEMIC ACHIEVEMENT OF THE DISADVANTAGED... State's accountability system must— (1) Be based on the State's academic standards under § 200.1, academic assessments under § 200.2, and other academic indicators under § 200.19; (2) Take into account the...

34 CFR 200.12 - Single State accountability system.

Code of Federal Regulations, 2011 CFR

2011-07-01

... SECONDARY EDUCATION, DEPARTMENT OF EDUCATION TITLE I-IMPROVING THE ACADEMIC ACHIEVEMENT OF THE DISADVANTAGED... State's accountability system must— (1) Be based on the State's academic standards under § 200.1, academic assessments under § 200.2, and other academic indicators under § 200.19; (2) Take into account the...

24 CFR 200.625 - Affirmative fair housing marketing plan.

Code of Federal Regulations, 2010 CFR

2010-04-01

... plan. 200.625 Section 200.625 Housing and Urban Development Regulations Relating to Housing and Urban... Regulations § 200.625 Affirmative fair housing marketing plan. Each applicant for participation in FHA housing... information indicating his affirmative fair housing marketing plan to comply with the requirements set forth...

13 CFR 500.200 - Eligible Borrower.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 13 Business Credit and Assistance 1 2013-01-01 2013-01-01 false Eligible Borrower. 500.200 Section 500.200 Business Credit and Assistance EMERGENCY OIL AND GAS GUARANTEED LOAN BOARD EMERGENCY OIL AND GAS GUARANTEED LOAN PROGRAM Oil and Gas Guaranteed Loans § 500.200 Eligible Borrower. (a) An eligible...

13 CFR 500.200 - Eligible Borrower.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 13 Business Credit and Assistance 1 2014-01-01 2014-01-01 false Eligible Borrower. 500.200 Section 500.200 Business Credit and Assistance EMERGENCY OIL AND GAS GUARANTEED LOAN BOARD EMERGENCY OIL AND GAS GUARANTEED LOAN PROGRAM Oil and Gas Guaranteed Loans § 500.200 Eligible Borrower. (a) An eligible...

13 CFR 500.200 - Eligible Borrower.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 13 Business Credit and Assistance 1 2012-01-01 2012-01-01 false Eligible Borrower. 500.200 Section 500.200 Business Credit and Assistance EMERGENCY OIL AND GAS GUARANTEED LOAN BOARD EMERGENCY OIL AND GAS GUARANTEED LOAN PROGRAM Oil and Gas Guaranteed Loans § 500.200 Eligible Borrower. (a) An eligible...

13 CFR 500.200 - Eligible Borrower.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 13 Business Credit and Assistance 1 2011-01-01 2011-01-01 false Eligible Borrower. 500.200 Section 500.200 Business Credit and Assistance EMERGENCY OIL AND GAS GUARANTEED LOAN BOARD EMERGENCY OIL AND GAS GUARANTEED LOAN PROGRAM Oil and Gas Guaranteed Loans § 500.200 Eligible Borrower. (a) An eligible...

41 CFR 102-117.200 - What is HAZMAT?

Code of Federal Regulations, 2014 CFR

2014-01-01

... 41 Public Contracts and Property Management 3 2014-01-01 2014-01-01 false What is HAZMAT? 102-117.200 Section 102-117.200 Public Contracts and Property Management Federal Property Management... Shipping Hazardous Material (HAZMAT) § 102-117.200 What is HAZMAT? HAZMAT is a substance or material the...

49 CFR 381.200 - What is a waiver?

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 5 2010-10-01 2010-10-01 false What is a waiver? 381.200 Section 381.200 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER SAFETY... PILOT PROGRAMS Procedures for Requesting Waivers § 381.200 What is a waiver? (a) A waiver is temporary...

41 CFR 102-117.200 - What is HAZMAT?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What is HAZMAT? 102-117.200 Section 102-117.200 Public Contracts and Property Management Federal Property Management... Shipping Hazardous Material (HAZMAT) § 102-117.200 What is HAZMAT? HAZMAT is a substance or material the...

24 CFR 200.635 - Compliance.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Compliance. 200.635 Section 200.635... GENERAL INTRODUCTION TO FHA PROGRAMS Affirmative Fair Housing Marketing Regulations § 200.635 Compliance... Department will enforce compliance through the procedures outlined in 24 CFR part 108. [37 FR 75, Jan. 5...

24 CFR 200.635 - Compliance.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Compliance. 200.635 Section 200.635... GENERAL INTRODUCTION TO FHA PROGRAMS Affirmative Fair Housing Marketing Regulations § 200.635 Compliance... Department will enforce compliance through the procedures outlined in 24 CFR part 108. [37 FR 75, Jan. 5...

34 CFR 200.41 - School improvement plan.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 34 Education 1 2011-07-01 2011-07-01 false School improvement plan. 200.41 Section 200.41... Basic Programs Operated by Local Educational Agencies Lea and School Improvement § 200.41 School improvement plan. (a)(1) Not later than three months after an LEA has identified a school for improvement...

12 CFR 563.200 - Conflicts of interest.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Conflicts of interest. 563.200 Section 563.200...-OPERATIONS Reporting and Bonding § 563.200 Conflicts of interest. If you are a director, officer, or employee...'s decision on the matter or transaction, including: (i) The existence, nature and extent of your...

10 CFR 607.200 - What must I do to comply with this part?

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false What must I do to comply with this part? 607.200 Section 607.200 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Requirements for Recipients Other Than Individuals § 607.200...

42 CFR 421.200 - Carrier functions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 3 2010-10-01 2010-10-01 false Carrier functions. 421.200 Section 421.200 Public...) MEDICARE PROGRAM MEDICARE CONTRACTING Carriers § 421.200 Carrier functions. A contract between CMS and a carrier specifies the functions to be performed by the carrier. The contract may include any or all of the...

13 CFR 101.200 - When does SBA hire private counsel?

Code of Federal Regulations, 2011 CFR

2011-01-01

... 13 Business Credit and Assistance 1 2011-01-01 2011-01-01 false When does SBA hire private counsel? 101.200 Section 101.200 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION ADMINISTRATION Employment of Private Counsel § 101.200 When does SBA hire private counsel? (a) Business loans. SBA may hire...

13 CFR 101.200 - When does SBA hire private counsel?

Code of Federal Regulations, 2010 CFR

2010-01-01

... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false When does SBA hire private counsel? 101.200 Section 101.200 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION ADMINISTRATION Employment of Private Counsel § 101.200 When does SBA hire private counsel? (a) Business loans. SBA may hire...

17 CFR 200.43 - Disposition of business by exercise of authority delegated to individual Commissioner.

Code of Federal Regulations, 2012 CFR

2012-04-01

... exercise of authority delegated to individual Commissioner. 200.43 Section 200.43 Commodity and Securities... Disposition of Commission Business § 200.43 Disposition of business by exercise of authority delegated to... Commission; Provided, however, That no such delegation shall authorize the duty officer (i) to exercise the...

17 CFR 200.43 - Disposition of business by exercise of authority delegated to individual Commissioner.

Code of Federal Regulations, 2014 CFR

2014-04-01

... exercise of authority delegated to individual Commissioner. 200.43 Section 200.43 Commodity and Securities... Disposition of Commission Business § 200.43 Disposition of business by exercise of authority delegated to... Commission; Provided, however, That no such delegation shall authorize the duty officer (i) to exercise the...

17 CFR 200.43 - Disposition of business by exercise of authority delegated to individual Commissioner.

Code of Federal Regulations, 2013 CFR

2013-04-01

... exercise of authority delegated to individual Commissioner. 200.43 Section 200.43 Commodity and Securities... Disposition of Commission Business § 200.43 Disposition of business by exercise of authority delegated to... Commission; Provided, however, That no such delegation shall authorize the duty officer (i) to exercise the...

17 CFR 200.43 - Disposition of business by exercise of authority delegated to individual Commissioner.

Code of Federal Regulations, 2011 CFR

2011-04-01

... exercise of authority delegated to individual Commissioner. 200.43 Section 200.43 Commodity and Securities... Disposition of Commission Business § 200.43 Disposition of business by exercise of authority delegated to... Commission; Provided, however, That no such delegation shall authorize the duty officer (i) to exercise the...

24 CFR 598.200 - Who nominates an area for designation?

Code of Federal Regulations, 2012 CFR

2012-04-01

... designation? 598.200 Section 598.200 Housing and Urban Development Regulations Relating to Housing and Urban... DESIGNATIONS Nomination Procedure § 598.200 Who nominates an area for designation? Applicants for empowerment... the area is located, except as provided in §§ 598.500, 598.510, and 598.515. The nomination must be...

24 CFR 598.200 - Who nominates an area for designation?

Code of Federal Regulations, 2013 CFR

2013-04-01

... designation? 598.200 Section 598.200 Housing and Urban Development Regulations Relating to Housing and Urban... DESIGNATIONS Nomination Procedure § 598.200 Who nominates an area for designation? Applicants for empowerment... the area is located, except as provided in §§ 598.500, 598.510, and 598.515. The nomination must be...

24 CFR 598.200 - Who nominates an area for designation?

Code of Federal Regulations, 2014 CFR

2014-04-01

... designation? 598.200 Section 598.200 Housing and Urban Development Regulations Relating to Housing and Urban... DESIGNATIONS Nomination Procedure § 598.200 Who nominates an area for designation? Applicants for empowerment... the area is located, except as provided in §§ 598.500, 598.510, and 598.515. The nomination must be...

49 CFR 179.200-8 - Tank heads.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 3 2012-10-01 2012-10-01 false Tank heads. 179.200-8 Section 179.200-8... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) SPECIFICATIONS FOR TANK CARS Specifications for Non-Pressure Tank Car Tanks (Classes DOT-111AW and 115AW) § 179.200-8 Tank heads. (a) All external tank heads...

49 CFR 179.200-8 - Tank heads.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 3 2011-10-01 2011-10-01 false Tank heads. 179.200-8 Section 179.200-8... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) SPECIFICATIONS FOR TANK CARS Specifications for Non-Pressure Tank Car Tanks (Classes DOT-111AW and 115AW) § 179.200-8 Tank heads. (a) All external tank heads...

4 CFR 200.12 - Notification of systems of Privacy Act records.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 4 Accounts 1 2010-01-01 2010-01-01 false Notification of systems of Privacy Act records. 200.12 Section 200.12 Accounts RECOVERY ACCOUNTABILITY AND TRANSPARENCY BOARD PRIVACY ACT OF 1974 § 200.12 Notification of systems of Privacy Act records. (a) Public notice. The Board periodically reviews its systems...

4 CFR 200.16 - Mailing lists.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 4 Accounts 1 2010-01-01 2010-01-01 false Mailing lists. 200.16 Section 200.16 Accounts RECOVERY ACCOUNTABILITY AND TRANSPARENCY BOARD PRIVACY ACT OF 1974 § 200.16 Mailing lists. The Board shall not sell or rent an individual's name and/or address unless such action is specifically authorized by law. This...

4 CFR 200.7 - Fees.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 4 Accounts 1 2010-01-01 2010-01-01 false Fees. 200.7 Section 200.7 Accounts RECOVERY ACCOUNTABILITY AND TRANSPARENCY BOARD PRIVACY ACT OF 1974 § 200.7 Fees. A fee will not be charged for searching, reviewing, or making corrections to records. A fee for copying will be assessed at the same rate established...

4 CFR 200.3 - Privacy Act records maintained by the Board.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 4 Accounts 1 2010-01-01 2010-01-01 false Privacy Act records maintained by the Board. 200.3 Section 200.3 Accounts RECOVERY ACCOUNTABILITY AND TRANSPARENCY BOARD PRIVACY ACT OF 1974 § 200.3 Privacy Act records maintained by the Board. (a) The Board shall maintain only such information about an...

21 CFR 73.200 - Synthetic iron oxide.

Code of Federal Regulations, 2012 CFR

2012-04-01

... COLOR ADDITIVES EXEMPT FROM CERTIFICATION Foods § 73.200 Synthetic iron oxide. (a) Identity. (1) The... suitable and that are listed in this subpart as safe for use in color additive mixtures for coloring foods... 21 Food and Drugs 1 2012-04-01 2012-04-01 false Synthetic iron oxide. 73.200 Section 73.200 Food...

21 CFR 73.200 - Synthetic iron oxide.

Code of Federal Regulations, 2013 CFR

2013-04-01

... COLOR ADDITIVES EXEMPT FROM CERTIFICATION Foods § 73.200 Synthetic iron oxide. (a) Identity. (1) The... suitable and that are listed in this subpart as safe for use in color additive mixtures for coloring foods... 21 Food and Drugs 1 2013-04-01 2013-04-01 false Synthetic iron oxide. 73.200 Section 73.200 Food...

21 CFR 73.200 - Synthetic iron oxide.

Code of Federal Regulations, 2014 CFR

2014-04-01

... COLOR ADDITIVES EXEMPT FROM CERTIFICATION Foods § 73.200 Synthetic iron oxide. (a) Identity. (1) The... suitable and that are listed in this subpart as safe for use in color additive mixtures for coloring foods... 21 Food and Drugs 1 2014-04-01 2014-04-01 false Synthetic iron oxide. 73.200 Section 73.200 Food...

43 CFR 46.200 - Applying NEPA early.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 43 Public Lands: Interior 1 2014-10-01 2014-10-01 false Applying NEPA early. 46.200 Section 46.200... ENVIRONMENTAL POLICY ACT OF 1969 Initiating the NEPA Process § 46.200 Applying NEPA early. (a) For any... environmental impacts, bureaus must coordinate, as early as feasible, with: (1) Any other bureaus or Federal...

43 CFR 46.200 - Applying NEPA early.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 43 Public Lands: Interior 1 2013-10-01 2013-10-01 false Applying NEPA early. 46.200 Section 46.200... ENVIRONMENTAL POLICY ACT OF 1969 Initiating the NEPA Process § 46.200 Applying NEPA early. (a) For any... environmental impacts, bureaus must coordinate, as early as feasible, with: (1) Any other bureaus or Federal...

43 CFR 46.200 - Applying NEPA early.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 43 Public Lands: Interior 1 2012-10-01 2011-10-01 true Applying NEPA early. 46.200 Section 46.200... ENVIRONMENTAL POLICY ACT OF 1969 Initiating the NEPA Process § 46.200 Applying NEPA early. (a) For any... environmental impacts, bureaus must coordinate, as early as feasible, with: (1) Any other bureaus or Federal...

23 CFR 200.7 - FHWA Title VI policy.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 23 Highways 1 2010-04-01 2010-04-01 false FHWA Title VI policy. 200.7 Section 200.7 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CIVIL RIGHTS TITLE VI PROGRAM AND RELATED STATUTES-IMPLEMENTATION AND REVIEW PROCEDURES § 200.7 FHWA Title VI policy. It is the policy of the FHWA to...

23 CFR 200.7 - FHWA Title VI policy.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 23 Highways 1 2011-04-01 2011-04-01 false FHWA Title VI policy. 200.7 Section 200.7 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CIVIL RIGHTS TITLE VI PROGRAM AND RELATED STATUTES-IMPLEMENTATION AND REVIEW PROCEDURES § 200.7 FHWA Title VI policy. It is the policy of the FHWA to...

23 CFR 200.7 - FHWA Title VI policy.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 23 Highways 1 2014-04-01 2014-04-01 false FHWA Title VI policy. 200.7 Section 200.7 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CIVIL RIGHTS TITLE VI PROGRAM AND RELATED STATUTES-IMPLEMENTATION AND REVIEW PROCEDURES § 200.7 FHWA Title VI policy. It is the policy of the FHWA to...

23 CFR 200.7 - FHWA Title VI policy.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 23 Highways 1 2013-04-01 2013-04-01 false FHWA Title VI policy. 200.7 Section 200.7 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CIVIL RIGHTS TITLE VI PROGRAM AND RELATED STATUTES-IMPLEMENTATION AND REVIEW PROCEDURES § 200.7 FHWA Title VI policy. It is the policy of the FHWA to...

29 CFR 778.200 - Provisions governing inclusion, exclusion, and crediting of particular payments.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 29 Labor 3 2014-07-01 2014-07-01 false Provisions governing inclusion, exclusion, and crediting of particular payments. 778.200 Section 778.200 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR... Provisions § 778.200 Provisions governing inclusion, exclusion, and crediting of particular payments. (a...

29 CFR 778.200 - Provisions governing inclusion, exclusion, and crediting of particular payments.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 29 Labor 3 2013-07-01 2013-07-01 false Provisions governing inclusion, exclusion, and crediting of particular payments. 778.200 Section 778.200 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR... Provisions § 778.200 Provisions governing inclusion, exclusion, and crediting of particular payments. (a...

29 CFR 778.200 - Provisions governing inclusion, exclusion, and crediting of particular payments.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 29 Labor 3 2012-07-01 2012-07-01 false Provisions governing inclusion, exclusion, and crediting of particular payments. 778.200 Section 778.200 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR... Provisions § 778.200 Provisions governing inclusion, exclusion, and crediting of particular payments. (a...

34 CFR 200.51 - Notice of SEA action.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 34 Education 1 2012-07-01 2012-07-01 false Notice of SEA action. 200.51 Section 200.51 Education... Programs Operated by Local Educational Agencies Lea and School Improvement § 200.51 Notice of SEA action. (a) In general. (1) An SEA must— (i) Communicate with parents throughout the review of an LEA under...

34 CFR 200.51 - Notice of SEA action.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 34 Education 1 2011-07-01 2011-07-01 false Notice of SEA action. 200.51 Section 200.51 Education... Programs Operated by Local Educational Agencies Lea and School Improvement § 200.51 Notice of SEA action. (a) In general. (1) An SEA must— (i) Communicate with parents throughout the review of an LEA under...

34 CFR 200.51 - Notice of SEA action.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 34 Education 1 2014-07-01 2014-07-01 false Notice of SEA action. 200.51 Section 200.51 Education... Programs Operated by Local Educational Agencies Lea and School Improvement § 200.51 Notice of SEA action. (a) In general. (1) An SEA must— (i) Communicate with parents throughout the review of an LEA under...

34 CFR 200.51 - Notice of SEA action.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 34 Education 1 2010-07-01 2010-07-01 false Notice of SEA action. 200.51 Section 200.51 Education... Programs Operated by Local Educational Agencies Lea and School Improvement § 200.51 Notice of SEA action. (a) In general. (1) An SEA must— (i) Communicate with parents throughout the review of an LEA under...

34 CFR 200.51 - Notice of SEA action.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 34 Education 1 2013-07-01 2013-07-01 false Notice of SEA action. 200.51 Section 200.51 Education... Programs Operated by Local Educational Agencies Lea and School Improvement § 200.51 Notice of SEA action. (a) In general. (1) An SEA must— (i) Communicate with parents throughout the review of an LEA under...

21 CFR 200.200 - Prescription drugs; reminder advertisements and reminder labeling to provide price information to...

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 4 2011-04-01 2011-04-01 false Prescription drugs; reminder advertisements and... AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL GENERAL Prescription Drug Consumer Price Listing § 200.200 Prescription drugs; reminder advertisements and reminder...

21 CFR 200.200 - Prescription drugs; reminder advertisements and reminder labeling to provide price information to...

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 4 2013-04-01 2013-04-01 false Prescription drugs; reminder advertisements and... AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL GENERAL Prescription Drug Consumer Price Listing § 200.200 Prescription drugs; reminder advertisements and reminder...

21 CFR 200.200 - Prescription drugs; reminder advertisements and reminder labeling to provide price information to...

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 4 2014-04-01 2014-04-01 false Prescription drugs; reminder advertisements and... AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL GENERAL Prescription Drug Consumer Price Listing § 200.200 Prescription drugs; reminder advertisements and reminder...

21 CFR 200.200 - Prescription drugs; reminder advertisements and reminder labeling to provide price information to...

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 4 2012-04-01 2012-04-01 false Prescription drugs; reminder advertisements and... AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL GENERAL Prescription Drug Consumer Price Listing § 200.200 Prescription drugs; reminder advertisements and reminder...

12 CFR 411.200 - Agency and legislative liaison.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Agency and legislative liaison. 411.200 Section 411.200 Banks and Banking EXPORT-IMPORT BANK OF THE UNITED STATES NEW RESTRICTIONS ON LOBBYING Activities by Own Employees § 411.200 Agency and legislative liaison. (a) The prohibition on the use of...

38 CFR 17.200 - Audit of State homes.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 1 2014-07-01 2014-07-01 false Audit of State homes. 17.200 Section 17.200 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS MEDICAL Aid to States for Care of Veterans in State Homes § 17.200 Audit of State homes. The State must comply...

38 CFR 17.200 - Audit of State homes.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Audit of State homes. 17.200 Section 17.200 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS MEDICAL Aid to States for Care of Veterans in State Homes § 17.200 Audit of State homes. The State must comply...

38 CFR 17.200 - Audit of State homes.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 1 2013-07-01 2013-07-01 false Audit of State homes. 17.200 Section 17.200 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS MEDICAL Aid to States for Care of Veterans in State Homes § 17.200 Audit of State homes. The State must comply...

38 CFR 17.200 - Audit of State homes.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 1 2012-07-01 2012-07-01 false Audit of State homes. 17.200 Section 17.200 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS MEDICAL Aid to States for Care of Veterans in State Homes § 17.200 Audit of State homes. The State must comply...

38 CFR 17.200 - Audit of State homes.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 1 2011-07-01 2011-07-01 false Audit of State homes. 17.200 Section 17.200 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS MEDICAL Aid to States for Care of Veterans in State Homes § 17.200 Audit of State homes. The State must comply...

49 CFR 179.200-10 - Welding.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 2 2010-10-01 2010-10-01 false Welding. 179.200-10 Section 179.200-10... Specifications for Non-Pressure Tank Car Tanks (Classes DOT-111AW and 115AW) § 179.200-10 Welding. (a) All joints... W (IBR, see § 171.7 of this subchapter). Welding procedures, welders and fabricators shall be...

30 CFR 212.200 - Maintenance of and access to records.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Maintenance of and access to records. 212.200 Section 212.200 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE MANAGEMENT RECORDS AND FILES MAINTENANCE Reserved § 212.200 Maintenance of and access to records. (a) All...

2 CFR 200.466 - Scholarships and student aid costs.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Scholarships and student aid costs. 200.466 Section 200.466 Grants and Agreements Office of Management and Budget Guidance for Grants and Agreements... Cost § 200.466 Scholarships and student aid costs. (a) Costs of scholarships, fellowships, and other...

20 CFR 664.200 - Who is eligible for youth services?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Who is eligible for youth services? 664.200 Section 664.200 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR YOUTH ACTIVITIES UNDER TITLE I OF THE WORKFORCE INVESTMENT ACT Eligibility for Youth Services § 664.200 Who is...

41 CFR 302-8.200 - Am I eligible for extended storage during assignment OCONUS?

Code of Federal Regulations, 2012 CFR

2012-07-01

... extended storage during assignment OCONUS? 302-8.200 Section 302-8.200 Public Contracts and Property...-ALLOWANCES FOR EXTENDED STORAGE OF HOUSEHOLD GOODS (HHG) Extended Storage During Assignment Outside the Continental United States (OCONUS) § 302-8.200 Am I eligible for extended storage during assignment OCONUS...

41 CFR 302-8.200 - Am I eligible for extended storage during assignment OCONUS?

Code of Federal Regulations, 2010 CFR

2010-07-01

... extended storage during assignment OCONUS? 302-8.200 Section 302-8.200 Public Contracts and Property...-ALLOWANCES FOR EXTENDED STORAGE OF HOUSEHOLD GOODS (HHG) Extended Storage During Assignment Outside the Continental United States (OCONUS) § 302-8.200 Am I eligible for extended storage during assignment OCONUS...

41 CFR 302-8.200 - Am I eligible for extended storage during assignment OCONUS?

Code of Federal Regulations, 2011 CFR

2011-07-01

... extended storage during assignment OCONUS? 302-8.200 Section 302-8.200 Public Contracts and Property...-ALLOWANCES FOR EXTENDED STORAGE OF HOUSEHOLD GOODS (HHG) Extended Storage During Assignment Outside the Continental United States (OCONUS) § 302-8.200 Am I eligible for extended storage during assignment OCONUS...

43 CFR 46.200 - Applying NEPA early.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 43 Public Lands: Interior 1 2011-10-01 2011-10-01 false Applying NEPA early. 46.200 Section 46.200... ENVIRONMENTAL POLICY ACT OF 1969 Initiating the NEPA Process § 46.200 Applying NEPA early. (a) For any... environmental impacts, bureaus must coordinate, as early as feasible, with: (1) Any other bureaus or Federal...

34 CFR 200.6 - Inclusion of all students.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 34 Education 1 2010-07-01 2010-07-01 false Inclusion of all students. 200.6 Section 200.6... Basic Programs Operated by Local Educational Agencies Standards and Assessments § 200.6 Inclusion of all...— (A) For each student with a disability, as defined under section 602(3) of the IDEA, appropriate...

29 CFR 778.200 - Provisions governing inclusion, exclusion, and crediting of particular payments.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 3 2010-07-01 2010-07-01 false Provisions governing inclusion, exclusion, and crediting of particular payments. 778.200 Section 778.200 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR... Provisions § 778.200 Provisions governing inclusion, exclusion, and crediting of particular payments. (a...

2 CFR 200.444 - General costs of government.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false General costs of government. 200.444 Section... Cost § 200.444 General costs of government. (a) For states, local governments, and Indian Tribes, the general costs of government are unallowable (except as provided in § 200.474 Travel costs). Unallowable...

34 CFR 82.200 - Agency and legislative liaison.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 34 Education 1 2010-07-01 2010-07-01 false Agency and legislative liaison. 82.200 Section 82.200 Education Office of the Secretary, Department of Education NEW RESTRICTIONS ON LOBBYING Activities by Own Employees § 82.200 Agency and legislative liaison. (a) The prohibition on the use of appropriated funds, in...

24 CFR 200.1530 - Bases for sanctioning a MAP lender.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Bases for sanctioning a MAP lender. 200.1530 Section 200.1530 Housing and Urban Development Regulations Relating to Housing and Urban...): MAP Lender Quality Assurance Enforcement § 200.1530 Bases for sanctioning a MAP lender. It is HUD...

24 CFR 200.1530 - Bases for sanctioning a MAP lender.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 2 2013-04-01 2013-04-01 false Bases for sanctioning a MAP lender. 200.1530 Section 200.1530 Housing and Urban Development Regulations Relating to Housing and Urban...): MAP Lender Quality Assurance Enforcement § 200.1530 Bases for sanctioning a MAP lender. It is HUD...

24 CFR 200.1530 - Bases for sanctioning a MAP lender.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Bases for sanctioning a MAP lender. 200.1530 Section 200.1530 Housing and Urban Development Regulations Relating to Housing and Urban...): MAP Lender Quality Assurance Enforcement § 200.1530 Bases for sanctioning a MAP lender. It is HUD...

4 CFR 200.3 - Privacy Act records maintained by the Board.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 4 Accounts 1 2013-01-01 2013-01-01 false Privacy Act records maintained by the Board. 200.3 Section 200.3 Accounts RECOVERY ACCOUNTABILITY AND TRANSPARENCY BOARD PRIVACY ACT OF 1974 § 200.3 Privacy Act records maintained by the Board. (a) The Board shall maintain only such information about an...

4 CFR 200.3 - Privacy Act records maintained by the Board.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 4 Accounts 1 2012-01-01 2012-01-01 false Privacy Act records maintained by the Board. 200.3 Section 200.3 Accounts RECOVERY ACCOUNTABILITY AND TRANSPARENCY BOARD PRIVACY ACT OF 1974 § 200.3 Privacy Act records maintained by the Board. (a) The Board shall maintain only such information about an...

4 CFR 200.3 - Privacy Act records maintained by the Board.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 4 Accounts 1 2011-01-01 2011-01-01 false Privacy Act records maintained by the Board. 200.3 Section 200.3 Accounts RECOVERY ACCOUNTABILITY AND TRANSPARENCY BOARD PRIVACY ACT OF 1974 § 200.3 Privacy Act records maintained by the Board. (a) The Board shall maintain only such information about an...

4 CFR 200.12 - Notification of systems of Privacy Act records.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 4 Accounts 1 2011-01-01 2011-01-01 false Notification of systems of Privacy Act records. 200.12 Section 200.12 Accounts RECOVERY ACCOUNTABILITY AND TRANSPARENCY BOARD PRIVACY ACT OF 1974 § 200.12 Notification of systems of Privacy Act records. (a) Public notice. The Board periodically reviews its systems...

4 CFR 200.12 - Notification of systems of Privacy Act records.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 4 Accounts 1 2013-01-01 2013-01-01 false Notification of systems of Privacy Act records. 200.12 Section 200.12 Accounts RECOVERY ACCOUNTABILITY AND TRANSPARENCY BOARD PRIVACY ACT OF 1974 § 200.12 Notification of systems of Privacy Act records. (a) Public notice. The Board periodically reviews its systems...

4 CFR 200.12 - Notification of systems of Privacy Act records.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 4 Accounts 1 2012-01-01 2012-01-01 false Notification of systems of Privacy Act records. 200.12 Section 200.12 Accounts RECOVERY ACCOUNTABILITY AND TRANSPARENCY BOARD PRIVACY ACT OF 1974 § 200.12 Notification of systems of Privacy Act records. (a) Public notice. The Board periodically reviews its systems...

9 CFR 592.200 - Debarment.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 9 Animals and Animal Products 2 2013-01-01 2013-01-01 false Debarment. 592.200 Section 592.200 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION VOLUNTARY INSPECTION OF EGG PRODUCTS Denial of Service § 592.200 Debarment. (a) The following acts or practices or the causing thereof may...

9 CFR 592.200 - Debarment.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false Debarment. 592.200 Section 592.200 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION VOLUNTARY INSPECTION OF EGG PRODUCTS Denial of Service § 592.200 Debarment. (a) The following acts or practices or the causing thereof may...

9 CFR 592.200 - Debarment.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 9 Animals and Animal Products 2 2014-01-01 2014-01-01 false Debarment. 592.200 Section 592.200 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION VOLUNTARY INSPECTION OF EGG PRODUCTS Denial of Service § 592.200 Debarment. (a) The following acts or practices or the causing thereof may...

14 CFR 1212.200 - Determining existence of records subject to the Privacy Act.

Code of Federal Regulations, 2010 CFR

2010-01-01

... requests under the Privacy Act made by individuals concerning records about themselves: (a) To determine if... the Privacy Act. 1212.200 Section 1212.200 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION PRIVACY ACT-NASA REGULATIONS Access to Records § 1212.200 Determining existence of records subject...

4 CFR 200.1 - Purpose and scope.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 4 Accounts 1 2010-01-01 2010-01-01 false Purpose and scope. 200.1 Section 200.1 Accounts RECOVERY ACCOUNTABILITY AND TRANSPARENCY BOARD PRIVACY ACT OF 1974 § 200.1 Purpose and scope. This part sets forth the policies and procedures of the Board regarding access to systems of records maintained by the Board under...

29 CFR 778.200 - Provisions governing inclusion, exclusion, and crediting of particular payments.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 29 Labor 3 2011-07-01 2011-07-01 false Provisions governing inclusion, exclusion, and crediting of particular payments. 778.200 Section 778.200 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR... Provisions § 778.200 Provisions governing inclusion, exclusion, and crediting of particular payments. (a...

Problems and Prospects of Turkey in the 1990s

DTIC Science & Technology

1992-04-01

water for personal consumption, irrigation and power generation. With the depletion of underground aquifers and the growing salinity and pollution of...100,000 Dammam 200,000 Homs 100,000 Al Khobar 200,000 Damascus 600,000 Hufuf 200,000 1,100,055 806,60s Bahrain Manama 200,000 Jordan Qatar Amman 600,008

17 CFR 200.24a - Director of the Office of Consumer Affairs.

Code of Federal Regulations, 2010 CFR

2010-04-01

... Consumer Affairs. 200.24a Section 200.24a Commodity and Securities Exchanges SECURITIES AND EXCHANGE... General Organization § 200.24a Director of the Office of Consumer Affairs. The Director of the Office of Consumer Affairs is responsible to the Chairman for the Commission's investor education and consumer...

17 CFR 7.200-7.201 - [Reserved

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false [Reserved] 7.200-7.201 Section 7.200-7.201 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION CONTRACT MARKET RULES ALTERED OR SUPPLEMENTED BY THE COMMISSION Board of Trade of the City of Chicago Rules § 7.200-7...

17 CFR 7.200-7.201 - [Reserved

Code of Federal Regulations, 2011 CFR

2011-04-01

... 17 Commodity and Securities Exchanges 1 2011-04-01 2011-04-01 false [Reserved] 7.200-7.201 Section 7.200-7.201 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION CONTRACT MARKET RULES ALTERED OR SUPPLEMENTED BY THE COMMISSION Board of Trade of the City of Chicago Rules § 7.200-7...

34 CFR 200.26 - Core elements of a schoolwide program.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 34 Education 1 2010-07-01 2010-07-01 false Core elements of a schoolwide program. 200.26 Section 200.26 Education Regulations of the Offices of the Department of Education OFFICE OF ELEMENTARY AND... Improving Basic Programs Operated by Local Educational Agencies Schoolwide Programs § 200.26 Core elements...