Sample records for frequency selective inversion

  1. Full Waveform Inversion with Multisource Frequency Selection of Marine Streamer Data

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Huang, Yunsong; Schuster, Gerard T.

    The theory and practice of multisource full waveform inversion of marine supergathers are described with a frequency-selection strategy. The key enabling property of frequency selection is that it eliminates the crosstalk among sources, thus overcoming the aperture mismatch of marine multisource inversion. Tests on multisource full waveform inversion of synthetic marine data and Gulf of Mexico data show speedups of 4× and 8×, respectively, compared to conventional full waveform inversion.

  2. Full Waveform Inversion with Multisource Frequency Selection of Marine Streamer Data

    DOE PAGES

    Huang, Yunsong; Schuster, Gerard T.

    2017-10-26

    The theory and practice of multisource full waveform inversion of marine supergathers are described with a frequency-selection strategy. The key enabling property of frequency selection is that it eliminates the crosstalk among sources, thus overcoming the aperture mismatch of marine multisource inversion. Tests on multisource full waveform inversion of synthetic marine data and Gulf of Mexico data show speedups of 4× and 8×, respectively, compared to conventional full waveform inversion.

  3. ENDOR with band-selective shaped inversion pulses

    NASA Astrophysics Data System (ADS)

    Tait, Claudia E.; Stoll, Stefan

    2017-04-01

    Electron Nuclear DOuble Resonance (ENDOR) is based on the measurement of nuclear transition frequencies through detection of changes in the polarization of electron transitions. In Davies ENDOR, the initial polarization is generated by a selective microwave inversion pulse. The rectangular inversion pulses typically used are characterized by a relatively low selectivity, with full inversion achieved only for a limited number of spin packets with small resonance offsets. With the introduction of pulse shaping to EPR, the rectangular inversion pulses can be replaced with shaped pulses with increased selectivity. Band-selective inversion pulses are characterized by almost rectangular inversion profiles, leading to full inversion for spin packets with resonance offsets within the pulse excitation bandwidth and leaving spin packets outside the excitation bandwidth largely unaffected. Here, we explore the consequences of using different band-selective amplitude-modulated pulses designed for NMR as the inversion pulse in ENDOR. We find an increased sensitivity for small hyperfine couplings compared to rectangular pulses of the same bandwidth. In echo-detected Davies-type ENDOR, finite Fourier series inversion pulses combine the advantages of increased absolute ENDOR sensitivity of short rectangular inversion pulses and increased sensitivity for small hyperfine couplings of long rectangular inversion pulses. The use of pulses with an almost rectangular frequency-domain profile also allows for increased control of the hyperfine contrast selectivity. At X-band, acquisition of echo transients as a function of radiofrequency and appropriate selection of integration windows during data processing allows efficient separation of contributions from weakly and strongly coupled nuclei in overlapping ENDOR spectra within a single experiment.

  4. A multi-frequency iterative imaging method for discontinuous inverse medium problem

    NASA Astrophysics Data System (ADS)

    Zhang, Lei; Feng, Lixin

    2018-06-01

    The inverse medium problem with discontinuous refractive index is a kind of challenging inverse problem. We employ the primal dual theory and fast solution of integral equations, and propose a new iterative imaging method. The selection criteria of regularization parameter is given by the method of generalized cross-validation. Based on multi-frequency measurements of the scattered field, a recursive linearization algorithm has been presented with respect to the frequency from low to high. We also discuss the initial guess selection strategy by semi-analytical approaches. Numerical experiments are presented to show the effectiveness of the proposed method.

  5. How much can history constrain adaptive evolution? A real-time evolutionary approach of inversion polymorphisms in Drosophila subobscura.

    PubMed

    Fragata, I; Lopes-Cunha, M; Bárbaro, M; Kellen, B; Lima, M; Santos, M A; Faria, G S; Santos, M; Matos, M; Simões, P

    2014-12-01

    Chromosomal inversions are present in a wide range of animals and plants, having an important role in adaptation and speciation. Although empirical evidence of their adaptive value is abundant, the role of different processes underlying evolution of chromosomal polymorphisms is not fully understood. History and selection are likely to shape inversion polymorphism variation to an extent yet largely unknown. Here, we perform a real-time evolution study addressing the role of historical constraints and selection in the evolution of these polymorphisms. We founded laboratory populations of Drosophila subobscura derived from three locations along the European cline and followed the evolutionary dynamics of inversion polymorphisms throughout the first 40 generations. At the beginning, populations were highly differentiated and remained so throughout generations. We report evidence of positive selection for some inversions, variable between foundations. Signs of negative selection were more frequent, in particular for most cold-climate standard inversions across the three foundations. We found that previously observed convergence at the phenotypic level in these populations was not associated with convergence in inversion frequencies. In conclusion, our study shows that selection has shaped the evolutionary dynamics of inversion frequencies, but doing so within the constraints imposed by previous history. Both history and selection are therefore fundamental to predict the evolutionary potential of different populations to respond to global environmental changes. © 2014 European Society For Evolutionary Biology. Journal of Evolutionary Biology © 2014 European Society For Evolutionary Biology.

  6. Decline in frequency of the 2La chromosomal inversion in Anopheles gambiae (s.s.) in Western Kenya: correlation with increase in ownership of insecticide-treated bed nets.

    PubMed

    Matoke-Muhia, Damaris; Gimnig, John E; Kamau, Luna; Shililu, Josephat; Bayoh, M Nabie; Walker, Edward D

    2016-06-10

    The 2La chromosomal inversion, a genetic polymorphism in An. gambiae (sensu stricto) (s.s.), is associated with adaptation to microclimatic differences in humidity and desiccation resistance and mosquito behaviors. Ownership of insecticide-treated bed nets (ITNs) for malaria control has increased markedly in western Kenya in the last 20 years. An increase in the frequency of ITNs indoors could select against house entering or indoor resting of Anopheles mosquitoes. Thus, the frequency of the 2La inversion is postulated to change in An. gambiae (s.s.) with the increase of ITN ownership over time. Anopheles gambiae mosquitoes were sampled between 1994 and 2011 using pyrethrum knockdown, bednet traps and human landing catches (HLC) from Asembo and Seme, western Kenya. The 2La inversion was detected by a PCR assay with primers designed for proximal breakpoints of the 2La/a and 2L+(a)/+(a) chromosomal conformation. Mosquitoes were tested for malaria parasite infection by sporozoite ELISA. The frequency of the 2La chromosomal inversion declined from 100 % of all chromosomes in 1994 to 17 % in 2005 and remained low through 2011 (21 %). ITN ownership increased from 0 to > 90 % of houses in the study area during this interval. The decline in the frequency of the 2La chromosomal inversion was significantly, negatively correlated with year (r = -0.93) and with increase in ITN ownership (r = -0.96). The frequency of the homo- and heterokaryotypes departed significantly from Hardy-Weinberg equilibrium, suggesting that 2La/a karyotype was under selection, earlier in its favor and later, against it. Precipitation and maximum monthly temperature did not vary over time, therefore there was no trend in climate that could account for the decline. There was no significant difference in frequency of the 2La inversion in An. gambiae (s.s.) females sampled indoors or outdoors in HCL in 2011, nor was there an association between the 2La inversion and infection with Plasmodium falciparum sporozoites. The increase in ITN ownership in the study area was negatively correlated with the frequency of 2La inversion. The decline in 2La frequency in western Kenya is postulated to be due to differential impacts of ITNs on mosquitoes with different 2La karyotypes, possibly mediated by differences in behavior associated with the 2La karyotypes. Further research is required to determine if this is a widespread phenomenon, to further determine the association of the 2La karyotypes with mosquito behavior, and to assess whether ITNs are exerting selection mediated by differences in behavior on the different karyotypes.

  7. Chromosome Inversion Polymorphisms in DROSOPHILA MELANOGASTER. I. Latitudinal Clines and Associations between Inversions in Australasian Populations

    PubMed Central

    Knibb, W. R.; Oakeshott, J. G.; Gibson, J. B.

    1981-01-01

    Nineteen Australasian populations of Drosophila melanogaster have been screened for chromosome inversion polymorphisms. All 15 of the inversion types found are paracentric and autosomal, but only four of these, one on each of the major autosome arms, are common and cosmopolitan. North-south clines occur, with the frequencies of all four of the common cosmopolitan inversions increasing toward the equator. These clines in the Southern Hemisphere mirror north-south clines in the Northern Hemisphere, where the frequencies of all four of the common cosmopolitan inversions again increase towards the equator.—While few of the Australasian populations show significant disequilibrium between linked common cosmopolitan inversions, those that do invariably have excesses of coupling gametes, which is consistent with other reports. We also find nonrandom associations between the two major autosomes, with the northern populations in Australasia (those with high inversion frequencies) tending to be deficient in gametes with common cosmopolitan inversions on both major autosomes, while the southern populations in Australasia (low inversion frequencies) tend to have an excess of this class of gametes.—The clines and the nonrandom associations between the two major autosomes are best interpreted in terms of selection operating to maintain the common cosmopolitan inversion polymorphisms in natural populations of D. melanogaster. PMID:17249108

  8. Inference of chromosomal inversion dynamics from Pool-Seq data in natural and laboratory populations of Drosophila melanogaster.

    PubMed

    Kapun, Martin; van Schalkwyk, Hester; McAllister, Bryant; Flatt, Thomas; Schlötterer, Christian

    2014-04-01

    Sequencing of pools of individuals (Pool-Seq) represents a reliable and cost-effective approach for estimating genome-wide SNP and transposable element insertion frequencies. However, Pool-Seq does not provide direct information on haplotypes so that, for example, obtaining inversion frequencies has not been possible until now. Here, we have developed a new set of diagnostic marker SNPs for seven cosmopolitan inversions in Drosophila melanogaster that can be used to infer inversion frequencies from Pool-Seq data. We applied our novel marker set to Pool-Seq data from an experimental evolution study and from North American and Australian latitudinal clines. In the experimental evolution data, we find evidence that positive selection has driven the frequencies of In(3R)C and In(3R)Mo to increase over time. In the clinal data, we confirm the existence of frequency clines for In(2L)t, In(3L)P and In(3R)Payne in both North America and Australia and detect a previously unknown latitudinal cline for In(3R)Mo in North America. The inversion markers developed here provide a versatile and robust tool for characterizing inversion frequencies and their dynamics in Pool-Seq data from diverse D. melanogaster populations. © 2013 The Authors. Molecular Ecology Published by John Wiley & Sons Ltd.

  9. Inference of chromosomal inversion dynamics from Pool-Seq data in natural and laboratory populations of Drosophila melanogaster

    PubMed Central

    Kapun, Martin; van Schalkwyk, Hester; McAllister, Bryant; Flatt, Thomas; Schlötterer, Christian

    2014-01-01

    Sequencing of pools of individuals (Pool-Seq) represents a reliable and cost-effective approach for estimating genome-wide SNP and transposable element insertion frequencies. However, Pool-Seq does not provide direct information on haplotypes so that, for example, obtaining inversion frequencies has not been possible until now. Here, we have developed a new set of diagnostic marker SNPs for seven cosmopolitan inversions in Drosophila melanogaster that can be used to infer inversion frequencies from Pool-Seq data. We applied our novel marker set to Pool-Seq data from an experimental evolution study and from North American and Australian latitudinal clines. In the experimental evolution data, we find evidence that positive selection has driven the frequencies of In(3R)C and In(3R)Mo to increase over time. In the clinal data, we confirm the existence of frequency clines for In(2L)t, In(3L)P and In(3R)Payne in both North America and Australia and detect a previously unknown latitudinal cline for In(3R)Mo in North America. The inversion markers developed here provide a versatile and robust tool for characterizing inversion frequencies and their dynamics in Pool-Seq data from diverse D. melanogaster populations. PMID:24372777

  10. Genomic Evidence for Adaptive Inversion Clines in Drosophila melanogaster.

    PubMed

    Kapun, Martin; Fabian, Daniel K; Goudet, Jérôme; Flatt, Thomas

    2016-05-01

    Clines in chromosomal inversion polymorphisms-presumably driven by climatic gradients-are common but there is surprisingly little evidence for selection acting on them. Here we address this long-standing issue in Drosophila melanogaster by using diagnostic single nucleotide polymorphism (SNP) markers to estimate inversion frequencies from 28 whole-genome Pool-seq samples collected from 10 populations along the North American east coast. Inversions In(3L)P, In(3R)Mo, and In(3R)Payne showed clear latitudinal clines, and for In(2L)t, In(2R)NS, and In(3R)Payne the steepness of the clinal slopes changed between summer and fall. Consistent with an effect of seasonality on inversion frequencies, we detected small but stable seasonal fluctuations of In(2R)NS and In(3R)Payne in a temperate Pennsylvanian population over 4 years. In support of spatially varying selection, we observed that the cline in In(3R)Payne has remained stable for >40 years and that the frequencies of In(2L)t and In(3R)Payne are strongly correlated with climatic factors that vary latitudinally, independent of population structure. To test whether these patterns are adaptive, we compared the amount of genetic differentiation of inversions versus neutral SNPs and found that the clines in In(2L)t and In(3R)Payne are maintained nonneutrally and independent of admixture. We also identified numerous clinal inversion-associated SNPs, many of which exhibit parallel differentiation along the Australian cline and reside in genes known to affect fitness-related traits. Together, our results provide strong evidence that inversion clines are maintained by spatially-and perhaps also temporally-varying selection. We interpret our data in light of current hypotheses about how inversions are established and maintained. © The Author 2016. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  11. Young inversion with multiple linked QTLs under selection in a hybrid zone.

    PubMed

    Lee, Cheng-Ruei; Wang, Baosheng; Mojica, Julius P; Mandáková, Terezie; Prasad, Kasavajhala V S K; Goicoechea, Jose Luis; Perera, Nadeesha; Hellsten, Uffe; Hundley, Hope N; Johnson, Jenifer; Grimwood, Jane; Barry, Kerrie; Fairclough, Stephen; Jenkins, Jerry W; Yu, Yeisoo; Kudrna, Dave; Zhang, Jianwei; Talag, Jayson; Golser, Wolfgang; Ghattas, Kathryn; Schranz, M Eric; Wing, Rod; Lysak, Martin A; Schmutz, Jeremy; Rokhsar, Daniel S; Mitchell-Olds, Thomas

    2017-04-03

    Fixed chromosomal inversions can reduce gene flow and promote speciation in two ways: by suppressing recombination and by carrying locally favoured alleles at multiple loci. However, it is unknown whether favoured mutations slowly accumulate on older inversions or if young inversions spread because they capture pre-existing adaptive quantitative trait loci (QTLs). By genetic mapping, chromosome painting and genome sequencing, we have identified a major inversion controlling ecologically important traits in Boechera stricta. The inversion arose since the last glaciation and subsequently reached local high frequency in a hybrid speciation zone. Furthermore, the inversion shows signs of positive directional selection. To test whether the inversion could have captured existing, linked QTLs, we crossed standard, collinear haplotypes from the hybrid zone and found multiple linked phenology QTLs within the inversion region. These findings provide the first direct evidence that linked, locally adapted QTLs may be captured by young inversions during incipient speciation.

  12. Young inversion with multiple linked QTLs under selection in a hybrid zone

    PubMed Central

    Lee, Cheng-Ruei; Wang, Baosheng; Mojica, Julius; Mandáková, Terezie; Prasad, Kasavajhala V. S. K.; Goicoechea, Jose Luis; Perera, Nadeesha; Hellsten, Uffe; Hundley, Hope N.; Johnson, Jenifer; Grimwood, Jane; Barry, Kerrie; Fairclough, Stephen; Jenkins, Jerry W.; Yu, Yeisoo; Kudrna, Dave; Zhang, Jianwei; Talag, Jayson; Golser, Wolfgang; Ghattas, Katherine; Schranz, M. Eric; Wing, Rod; Lysak, Martin A.; Schmutz, Jeremy; Rokhsar, Daniel S.; Mitchell-Olds, Thomas

    2017-01-01

    Fixed chromosomal inversions can reduce gene flow and promote speciation in two ways: by suppressing recombination and by carrying locally favored alleles at multiple loci. However, it is unknown whether favored mutations slowly accumulate on older inversions or if young inversions spread because they capture preexisting adaptive Quantitative Trait Loci (QTLs). By genetic mapping, chromosome painting and genome sequencing we have identified a major inversion controlling ecologically important traits in Boechera stricta. The inversion arose since the last glaciation and subsequently reached local high frequency in a hybrid speciation zone. Furthermore, the inversion shows signs of positive directional selection. To test whether the inversion could have captured existing, linked QTLs, we crossed standard, collinear haplotypes from the hybrid zone and found multiple linked phenology QTLs within the inversion region. These findings provide the first direct evidence that linked, locally adapted QTLs may be captured by young inversions during incipient speciation. PMID:28812690

  13. Crustal Structure Beneath Taiwan Using Frequency-band Inversion of Receiver Function Waveforms

    NASA Astrophysics Data System (ADS)

    Tomfohrde, D. A.; Nowack, R. L.

    Receiver function analysis is used to determine local crustal structure beneath Taiwan. We have performed preliminary data processing and polarization analysis for the selection of stations and events and to increase overall data quality. Receiver function analysis is then applied to data from the Taiwan Seismic Network to obtain radial and transverse receiver functions. Due to the limited azimuthal coverage, only the radial receiver functions are analyzed in terms of horizontally layered crustal structure for each station. In order to improve convergence of the receiver function inversion, frequency-band inversion (FBI) is implemented, in which an iterative inversion procedure with sequentially higher low-pass corner frequencies is used to stabilize the waveform inversion. Frequency-band inversion is applied to receiver functions at six stations of the Taiwan Seismic Network. Initial 20-layer crustal models are inverted for using prior tomographic results for the initial models. The resulting 20-1ayer models are then simplified to 4 to 5 layer models and input into an alternating depth and velocity frequency-band inversion. For the six stations investigated, the resulting simplified models provide an average estimate of 38 km for the Moho thickness surrounding the Central Range of Taiwan. Also, the individual station estimates compare well with the recent tomographic model of and the refraction results of Rau and Wu (1995) and the refraction results of Ma and Song (1997).

  14. Climatological characteristics of high altitude wind shear and lapse rate layers

    NASA Technical Reports Server (NTRS)

    Ehernberger, L. J.; Guttman, N. B.

    1981-01-01

    Indications of the climatological distribution of wind shear and temperature lapse and inversion rates as observed by rawinsonde measurements over the western United States are recorded. Frequencies of the strongest shear, lapse rates, and inversion layer strengths were observed for a 1 year period of record and were tabulated for the lower troposphere, the upper troposphere, and five altitude intervals in the lower stratosphere. Selected bivariate frequencies were also tabulated. Strong wind shears, lapse rates, and inversion are observed less frequently as altitude increases from 175 millibars to 20 millibars. On a seasonal basis the frequencies were higher in winter than in summer except for minor influences due to increased tropopause altitude in summer and the stratospheric wind reversal in the spring and fall.

  15. Population Genomics of Inversion Polymorphisms in Drosophila melanogaster

    PubMed Central

    Corbett-Detig, Russell B.; Hartl, Daniel L.

    2012-01-01

    Chromosomal inversions have been an enduring interest of population geneticists since their discovery in Drosophila melanogaster. Numerous lines of evidence suggest powerful selective pressures govern the distributions of polymorphic inversions, and these observations have spurred the development of many explanatory models. However, due to a paucity of nucleotide data, little progress has been made towards investigating selective hypotheses or towards inferring the genealogical histories of inversions, which can inform models of inversion evolution and suggest selective mechanisms. Here, we utilize population genomic data to address persisting gaps in our knowledge of D. melanogaster's inversions. We develop a method, termed Reference-Assisted Reassembly, to assemble unbiased, highly accurate sequences near inversion breakpoints, which we use to estimate the age and the geographic origins of polymorphic inversions. We find that inversions are young, and most are African in origin, which is consistent with the demography of the species. The data suggest that inversions interact with polymorphism not only in breakpoint regions but also chromosome-wide. Inversions remain differentiated at low levels from standard haplotypes even in regions that are distant from breakpoints. Although genetic exchange appears fairly extensive, we identify numerous regions that are qualitatively consistent with selective hypotheses. Finally, we show that In(1)Be, which we estimate to be ∼60 years old (95% CI 5.9 to 372.8 years), has likely achieved high frequency via sex-ratio segregation distortion in males. With deeper sampling, it will be possible to build on our inferences of inversion histories to rigorously test selective models—particularly those that postulate that inversions achieve a selective advantage through the maintenance of co-adapted allele complexes. PMID:23284285

  16. Chromosome 17: association of a large inversion polymorphism with corticosteroid response in asthma.

    PubMed

    Tantisira, Kelan G; Lazarus, Ross; Litonjua, Augusto A; Klanderman, Barbara; Weiss, Scott T

    2008-08-01

    A 900-kb inversion exists within a large region of conserved linkage disequilibrium (LD) on chromosome 17. CRHR1 is located within the inversion region and associated with inhaled corticosteroid response in asthma. We hypothesized that CRHR1 variants are in LD with the inversion, supporting a potential role for natural selection in the genetic response to corticosteroids. We genotyped six single nucleotide polymorphisms (SNPs) spanning chromosome 17: 40,410,565-42,372,240, including four SNPs defining inversion status. Similar allele frequencies and strong LD were noted between the inversion and a CRHR1 SNP previously associated with lung function response to inhaled corticosteroids. Each inversion-defining SNP was strongly associated with inhaled corticosteroid response in adult asthma (P values 0.002-0.005). The CRHR1 response to inhaled corticosteroids may thus be explained by natural selection resulting from inversion status or by long-range LD with another gene. Additional pharmacogenetic investigations into regions of chromosomal diversity, including copy number variation and inversions, are warranted.

  17. Time-frequency analysis-based time-windowing algorithm for the inverse synthetic aperture radar imaging of ships

    NASA Astrophysics Data System (ADS)

    Zhou, Peng; Zhang, Xi; Sun, Weifeng; Dai, Yongshou; Wan, Yong

    2018-01-01

    An algorithm based on time-frequency analysis is proposed to select an imaging time window for the inverse synthetic aperture radar imaging of ships. An appropriate range bin is selected to perform the time-frequency analysis after radial motion compensation. The selected range bin is that with the maximum mean amplitude among the range bins whose echoes are confirmed to be contributed by a dominant scatter. The criterion for judging whether the echoes of a range bin are contributed by a dominant scatter is key to the proposed algorithm and is therefore described in detail. When the first range bin that satisfies the judgment criterion is found, a sequence composed of the frequencies that have the largest amplitudes in every moment's time-frequency spectrum corresponding to this range bin is employed to calculate the length and the center moment of the optimal imaging time window. Experiments performed with simulation data and real data show the effectiveness of the proposed algorithm, and comparisons between the proposed algorithm and the image contrast-based algorithm (ICBA) are provided. Similar image contrast and lower entropy are acquired using the proposed algorithm as compared with those values when using the ICBA.

  18. The evolutionary history of Drosophila buzzatii. XXXII. Linkage disequilibrium between allozymes and chromosome inversions in two colonizing populations.

    PubMed

    Betrán, E; Quezada-Díaz, J E; Ruiz, A; Santos, M; Fontdevila, A

    1995-02-01

    Chromosome polymorphism in Drosophila buzzatii is under selection but the genes responsible for the effect of the inversions of fitness are unknown. On the other hand, there is evidence for selection on several allozyme loci but the presence of paracentric inversions on the second chromosome, where most of the polymorphic loci are located, complicates the interpretation. Studies of the associations between allozymes and inversions are thus necessary to help understand the effect of selection at both the chromosomal and allozymic level. Until now this kind of information has only been available in D. buzzatii for two loci, Est-1 and Est-2, in Australian populations. Here we describe the genetic constitution of two Old World populations, Carboneras and Colera. Emphasis has been placed on the analysis of the linkage disequilibria between the second chromosome arrangements and three allozyme loci, Est-2, Pept-2 and Aldox, located on this chromosome. In addition, the recombination frequencies between the loci, and between the loci and the inversion breakpoints, have been estimated and a genetic map of the three loci has been produced. The two populations differ in allele and arrangement frequencies, as well as in the pattern of one-locus disequilibria. Est-2 and Aldox are associated with the second chromosome arrangements in both populations. On the other hand, Pept-2 is associated with the inversions in Colera but not in Carboneras. The gametic associations among the three loci are discussed taking into account the position of these loci on the chromosome map and the lack of recombination in the heterokaryotypes.

  19. Local adaptation along an environmental cline in a species with an inversion polymorphism.

    PubMed

    Wellenreuther, M; Rosenquist, H; Jaksons, P; Larson, K W

    2017-06-01

    Polymorphic inversions are ubiquitous across the animal kingdom and are frequently associated with clines in inversion frequencies across environmental gradients. Such clines are thought to result from selection favouring local adaptation; however, empirical tests are scarce. The seaweed fly Coelopa frigida has an α/β inversion polymorphism, and previous work demonstrated that the α inversion frequency declines from the North Sea to the Baltic Sea and is correlated with changes in tidal range, salinity, algal composition and wrackbed stability. Here, we explicitly test the hypothesis that populations of C. frigida along this cline are locally adapted by conducting a reciprocal transplant experiment of four populations along this cline to quantify survival. We found that survival varied significantly across treatments and detected a significant Location x Substrate interaction, indicating local adaptation. Survival models showed that flies from locations at both extremes had highest survival on their native substrates, demonstrating that local adaptation is present at the extremes of the cline. Survival at the two intermediate locations was, however, not elevated at the native substrates, suggesting that gene flow in intermediate habitats may override selection. Together, our results support the notion that population extremes of species with polymorphic inversions are often locally adapted, even when spatially close, consistent with the growing view that inversions can have direct and strong effects on the fitness of species. © 2017 European Society For Evolutionary Biology. Journal of Evolutionary Biology © 2017 European Society For Evolutionary Biology.

  20. Data-resolution matrix and model-resolution matrix for Rayleigh-wave inversion using a damped least-squares method

    USGS Publications Warehouse

    Xia, J.; Miller, R.D.; Xu, Y.

    2008-01-01

    Inversion of multimode surface-wave data is of increasing interest in the near-surface geophysics community. For a given near-surface geophysical problem, it is essential to understand how well the data, calculated according to a layered-earth model, might match the observed data. A data-resolution matrix is a function of the data kernel (determined by a geophysical model and a priori information applied to the problem), not the data. A data-resolution matrix of high-frequency (>2 Hz) Rayleigh-wave phase velocities, therefore, offers a quantitative tool for designing field surveys and predicting the match between calculated and observed data. We employed a data-resolution matrix to select data that would be well predicted and we find that there are advantages of incorporating higher modes in inversion. The resulting discussion using the data-resolution matrix provides insight into the process of inverting Rayleigh-wave phase velocities with higher-mode data to estimate S-wave velocity structure. Discussion also suggested that each near-surface geophysical target can only be resolved using Rayleigh-wave phase velocities within specific frequency ranges, and higher-mode data are normally more accurately predicted than fundamental-mode data because of restrictions on the data kernel for the inversion system. We used synthetic and real-world examples to demonstrate that selected data with the data-resolution matrix can provide better inversion results and to explain with the data-resolution matrix why incorporating higher-mode data in inversion can provide better results. We also calculated model-resolution matrices in these examples to show the potential of increasing model resolution with selected surface-wave data. ?? Birkhaueser 2008.

  1. Extracting Low-Frequency Information from Time Attenuation in Elastic Waveform Inversion

    NASA Astrophysics Data System (ADS)

    Guo, Xuebao; Liu, Hong; Shi, Ying; Wang, Weihong

    2017-03-01

    Low-frequency information is crucial for recovering background velocity, but the lack of low-frequency information in field data makes inversion impractical without accurate initial models. Laplace-Fourier domain waveform inversion can recover a smooth model from real data without low-frequency information, which can be used for subsequent inversion as an ideal starting model. In general, it also starts with low frequencies and includes higher frequencies at later inversion stages, while the difference is that its ultralow frequency information comes from the Laplace-Fourier domain. Meanwhile, a direct implementation of the Laplace-transformed wavefield using frequency domain inversion is also very convenient. However, because broad frequency bands are often used in the pure time domain waveform inversion, it is difficult to extract the wavefields dominated by low frequencies in this case. In this paper, low-frequency components are constructed by introducing time attenuation into the recorded residuals, and the rest of the method is identical to the traditional time domain inversion. Time windowing and frequency filtering are also applied to mitigate the ambiguity of the inverse problem. Therefore, we can start at low frequencies and to move to higher frequencies. The experiment shows that the proposed method can achieve a good inversion result in the presence of a linear initial model and records without low-frequency information.

  2. Fitness consequences of polymorphic inversions in the zebra finch genome.

    PubMed

    Knief, Ulrich; Hemmrich-Stanisak, Georg; Wittig, Michael; Franke, Andre; Griffith, Simon C; Kempenaers, Bart; Forstmeier, Wolfgang

    2016-09-29

    Inversion polymorphisms constitute an evolutionary puzzle: they should increase embryo mortality in heterokaryotypic individuals but still they are widespread in some taxa. Some insect species have evolved mechanisms to reduce the cost of embryo mortality but humans have not. In birds, a detailed analysis is missing although intraspecific inversion polymorphisms are regarded as common. In Australian zebra finches (Taeniopygia guttata), two polymorphic inversions are known cytogenetically and we set out to detect these two and potentially additional inversions using genomic tools and study their effects on embryo mortality and other fitness-related and morphological traits. Using whole-genome SNP data, we screened 948 wild zebra finches for polymorphic inversions and describe four large (12-63 Mb) intraspecific inversion polymorphisms with allele frequencies close to 50 %. Using additional data from 5229 birds and 9764 eggs from wild and three captive zebra finch populations, we show that only the largest inversions increase embryo mortality in heterokaryotypic males, with surprisingly small effect sizes. We test for a heterozygote advantage on other fitness components but find no evidence for heterosis for any of the inversions. Yet, we find strong additive effects on several morphological traits. The mechanism that has carried the derived inversion haplotypes to such high allele frequencies remains elusive. It appears that selection has effectively minimized the costs associated with inversions in zebra finches. The highly skewed distribution of recombination events towards the chromosome ends in zebra finches and other estrildid species may function to minimize crossovers in the inverted regions.

  3. Moment-Tensor Spectra of Source Physics Experiments (SPE) Explosions in Granite

    NASA Astrophysics Data System (ADS)

    Yang, X.; Cleveland, M.

    2016-12-01

    We perform frequency-domain moment tensor inversions of Source Physics Experiments (SPE) explosions conducted in granite during Phase I of the experiment. We test the sensitivity of source moment-tensor spectra to factors such as the velocity model, selected dataset and smoothing and damping parameters used in the inversion to constrain the error bound of inverted source spectra. Using source moments and corner frequencies measured from inverted source spectra of these explosions, we develop a new explosion P-wave source model that better describes observed source spectra of these small and over-buried chemical explosions detonated in granite than classical explosion source models derived mainly from nuclear-explosion data. In addition to source moment and corner frequency, we analyze other features in the source spectra to investigate their physical causes.

  4. A trade-off between model resolution and variance with selected Rayleigh-wave data

    USGS Publications Warehouse

    Xia, J.; Miller, R.D.; Xu, Y.

    2008-01-01

    Inversion of multimode surface-wave data is of increasing interest in the near-surface geophysics community. For a given near-surface geophysical problem, it is essential to understand how well the data, calculated according to a layered-earth model, might match the observed data. A data-resolution matrix is a function of the data kernel (determined by a geophysical model and a priori information applied to the problem), not the data. A data-resolution matrix of high-frequency (??? 2 Hz) Rayleigh-wave phase velocities, therefore, offers a quantitative tool for designing field surveys and predicting the match between calculated and observed data. First, we employed a data-resolution matrix to select data that would be well predicted and to explain advantages of incorporating higher modes in inversion. The resulting discussion using the data-resolution matrix provides insight into the process of inverting Rayleigh-wave phase velocities with higher mode data to estimate S-wave velocity structure. Discussion also suggested that each near-surface geophysical target can only be resolved using Rayleigh-wave phase velocities within specific frequency ranges, and higher mode data are normally more accurately predicted than fundamental mode data because of restrictions on the data kernel for the inversion system. Second, we obtained an optimal damping vector in a vicinity of an inverted model by the singular value decomposition of a trade-off function of model resolution and variance. In the end of the paper, we used a real-world example to demonstrate that selected data with the data-resolution matrix can provide better inversion results and to explain with the data-resolution matrix why incorporating higher mode data in inversion can provide better results. We also calculated model-resolution matrices of these examples to show the potential of increasing model resolution with selected surface-wave data. With the optimal damping vector, we can improve and assess an inverted model obtained by a damped least-square method.

  5. Spectral inversion of frequency-domain IP data obtained in Haenam, South Korea

    NASA Astrophysics Data System (ADS)

    Kim, B.; Nam, M. J.; Son, J. S.

    2017-12-01

    Spectral induced polarization (SIP) method using a range of source frequencies have been performed for not only exploring minerals resources, but also engineering or environmental application. SIP interpretation first makes inversion of individual frequency data to obtain complex resistivity structures, which will further analyzed employing Cole-Cole model to explain the frequency-dependent characteristics. However, due to the difficulty in fitting Cole-Cole model, there is a movement to interpret complex resistivity structure inverted only from a single frequency data: that is so-called "complex resistivity survey". Further, simultaneous inversion of multi-frequency SIP data, rather than making a single frequency SIP data, has been studied to improve ambiguity and artefacts of independent single frequency inversion in obtaining a complex resistivity structure, even though the dispersion characteristics of complex resistivity with respect to source frequency. Employing the simultaneous inversion method, this study makes inversion of field SIP data obtained over epithermal mineralized area, Haenam, in the southernmost tip of South Korea. The area has a polarizable structure because of extensive hydrothermal alteration, gold-silver deposits. After the inversion, we compare between inversion results considering multi-frequency data and single frequency data set to evaluate the performance of simultaneous inversion of multi-frequency SIP data.

  6. Estimation of near-surface shear-wave velocity by inversion of Rayleigh waves

    USGS Publications Warehouse

    Xia, J.; Miller, R.D.; Park, C.B.

    1999-01-01

    The shear-wave (S-wave) velocity of near-surface materials (soil, rocks, pavement) and its effect on seismic-wave propagation are of fundamental interest in many groundwater, engineering, and environmental studies. Rayleigh-wave phase velocity of a layered-earth model is a function of frequency and four groups of earth properties: P-wave velocity, S-wave velocity, density, and thickness of layers. Analysis of the Jacobian matrix provides a measure of dispersion-curve sensitivity to earth properties. S-wave velocities are the dominant influence on a dispersion curve in a high-frequency range (>5 Hz) followed by layer thickness. An iterative solution technique to the weighted equation proved very effective in the high-frequency range when using the Levenberg-Marquardt and singular-value decomposition techniques. Convergence of the weighted solution is guaranteed through selection of the damping factor using the Levenberg-Marquardt method. Synthetic examples demonstrated calculation efficiency and stability of inverse procedures. We verify our method using borehole S-wave velocity measurements.Iterative solutions to the weighted equation by the Levenberg-Marquardt and singular-value decomposition techniques are derived to estimate near-surface shear-wave velocity. Synthetic and real examples demonstrate the calculation efficiency and stability of the inverse procedure. The inverse results of the real example are verified by borehole S-wave velocity measurements.

  7. Recovering Long-wavelength Velocity Models using Spectrogram Inversion with Single- and Multi-frequency Components

    NASA Astrophysics Data System (ADS)

    Ha, J.; Chung, W.; Shin, S.

    2015-12-01

    Many waveform inversion algorithms have been proposed in order to construct subsurface velocity structures from seismic data sets. These algorithms have suffered from computational burden, local minima problems, and the lack of low-frequency components. Computational efficiency can be improved by the application of back-propagation techniques and advances in computing hardware. In addition, waveform inversion algorithms, for obtaining long-wavelength velocity models, could avoid both the local minima problem and the effect of the lack of low-frequency components in seismic data. In this study, we proposed spectrogram inversion as a technique for recovering long-wavelength velocity models. In spectrogram inversion, decomposed frequency components from spectrograms of traces, in the observed and calculated data, are utilized to generate traces with reproduced low-frequency components. Moreover, since each decomposed component can reveal the different characteristics of a subsurface structure, several frequency components were utilized to analyze the velocity features in the subsurface. We performed the spectrogram inversion using a modified SEG/SEGE salt A-A' line. Numerical results demonstrate that spectrogram inversion could also recover the long-wavelength velocity features. However, inversion results varied according to the frequency components utilized. Based on the results of inversion using a decomposed single-frequency component, we noticed that robust inversion results are obtained when a dominant frequency component of the spectrogram was utilized. In addition, detailed information on recovered long-wavelength velocity models was obtained using a multi-frequency component combined with single-frequency components. Numerical examples indicate that various detailed analyses of long-wavelength velocity models can be carried out utilizing several frequency components.

  8. Genomics of Natural Populations: How Differentially Expressed Genes Shape the Evolution of Chromosomal Inversions in Drosophila pseudoobscura

    PubMed Central

    Fuller, Zachary L.; Haynes, Gwilym D.; Richards, Stephen; Schaeffer, Stephen W.

    2016-01-01

    Chromosomal rearrangements can shape the structure of genetic variation in the genome directly through alteration of genes at breakpoints or indirectly by holding combinations of genetic variants together due to reduced recombination. The third chromosome of Drosophila pseudoobscura is a model system to test hypotheses about how rearrangements are established in populations because its third chromosome is polymorphic for >30 gene arrangements that were generated by a series of overlapping inversion mutations. Circumstantial evidence has suggested that these gene arrangements are selected. Despite the expected homogenizing effects of extensive gene flow, the frequencies of arrangements form gradients or clines in nature, which have been stable since the system was first described >80 years ago. Furthermore, multiple arrangements exist at appreciable frequencies across several ecological niches providing the opportunity for heterokaryotypes to form. In this study, we tested whether genes are differentially expressed among chromosome arrangements in first instar larvae, adult females and males. In addition, we asked whether transcriptional patterns in heterokaryotypes are dominant, semidominant, overdominant, or underdominant. We find evidence for a significant abundance of differentially expressed genes across the inverted regions of the third chromosome, including an enrichment of genes involved in sensory perception for males. We find the majority of loci show additivity in heterokaryotypes. Our results suggest that multiple genes have expression differences among arrangements that were either captured by the original inversion mutation or accumulated after it reached polymorphic frequencies, providing a potential source of genetic variation for selection to act upon. These data suggest that the inversions are favored because of their indirect effect of recombination suppression that has held different combinations of differentially expressed genes together in the various gene arrangement backgrounds. PMID:27401754

  9. Two-dimensional frequency-domain acoustic full-waveform inversion with rugged topography

    NASA Astrophysics Data System (ADS)

    Zhang, Qian-Jiang; Dai, Shi-Kun; Chen, Long-Wei; Li, Kun; Zhao, Dong-Dong; Huang, Xing-Xing

    2015-09-01

    We studied finite-element-method-based two-dimensional frequency-domain acoustic FWI under rugged topography conditions. The exponential attenuation boundary condition suitable for rugged topography is proposed to solve the cutoff boundary problem as well as to consider the requirement of using the same subdivision grid in joint multifrequency inversion. The proposed method introduces the attenuation factor, and by adjusting it, acoustic waves are sufficiently attenuated in the attenuation layer to minimize the cutoff boundary effect. Based on the law of exponential attenuation, expressions for computing the attenuation factor and the thickness of attenuation layers are derived for different frequencies. In multifrequency-domain FWI, the conjugate gradient method is used to solve equations in the Gauss-Newton algorithm and thus minimize the computation cost in calculating the Hessian matrix. In addition, the effect of initial model selection and frequency combination on FWI is analyzed. Examples using numerical simulations and FWI calculations are used to verify the efficiency of the proposed method.

  10. Source-independent full waveform inversion of seismic data

    DOEpatents

    Lee, Ki Ha

    2006-02-14

    A set of seismic trace data is collected in an input data set that is first Fourier transformed in its entirety into the frequency domain. A normalized wavefield is obtained for each trace of the input data set in the frequency domain. Normalization is done with respect to the frequency response of a reference trace selected from the set of seismic trace data. The normalized wavefield is source independent, complex, and dimensionless. The normalized wavefield is shown to be uniquely defined as the normalized impulse response, provided that a certain condition is met for the source. This property allows construction of the inversion algorithm disclosed herein, without any source or source coupling information. The algorithm minimizes the error between data normalized wavefield and the model normalized wavefield. The methodology is applicable to any 3-D seismic problem, and damping may be easily included in the process.

  11. Mutational jackpot events generate effective frequency-dependent selection in adapting populations

    NASA Astrophysics Data System (ADS)

    Hallatschek, Oskar

    The site-frequency spectrum is one the most easily measurable quantities that characterize the genetic diversity of a population. While most neutral models predict that site frequency spectra should decay with increasing frequency, a high-frequency uptick has been reported in many populations. Anomalies in the high-frequency tail are particularly unsettling because the highest frequencies can be measured with greatest accuracy. Here, we show that an uptick in the spectrum of neutral mutations generally arises when mutant frequencies are dominated by rare jackpot events, mutational events with large descendant numbers. This leads to an effective pattern of frequency-dependent selection (or unstable internal equilibrium at one half frequency) that causes an accumulation of high-frequency polymorphic sites. We reproduce the known uptick occurring for recurrent hitchhiking (genetic draft) as well as rapid adaptation, and (in the future) generalize the shape of the high-frequency tail to other scenarios that are dominated by jackpot events, such as frequent range expansions. We also tackle (in the future) the inverse approach to use the high-frequency uptick for learning about the tail of the offspring number distribution. Positively selected alleles need to surpass, typically, an u NSF Career Award (PoLS), NIH NIGMS R01, Simons Foundation.

  12. Bayesian ISOLA: new tool for automated centroid moment tensor inversion

    NASA Astrophysics Data System (ADS)

    Vackář, Jiří; Burjánek, Jan; Gallovič, František; Zahradník, Jiří; Clinton, John

    2017-08-01

    We have developed a new, fully automated tool for the centroid moment tensor (CMT) inversion in a Bayesian framework. It includes automated data retrieval, data selection where station components with various instrumental disturbances are rejected and full-waveform inversion in a space-time grid around a provided hypocentre. A data covariance matrix calculated from pre-event noise yields an automated weighting of the station recordings according to their noise levels and also serves as an automated frequency filter suppressing noisy frequency ranges. The method is tested on synthetic and observed data. It is applied on a data set from the Swiss seismic network and the results are compared with the existing high-quality MT catalogue. The software package programmed in Python is designed to be as versatile as possible in order to be applicable in various networks ranging from local to regional. The method can be applied either to the everyday network data flow, or to process large pre-existing earthquake catalogues and data sets.

  13. Temporal structure of thermal inversions in Łeba (Poland)

    NASA Astrophysics Data System (ADS)

    Czarnecka, Małgorzata; Nidzgorska-Lencewicz, Jadwiga; Rawicki, Kacper

    2018-03-01

    This study presents the detailed characteristics of thermal inversions based on a 10-year aerological measurement series (2005-2014) conducted in Łeba (Poland). The analyses included surface-based inversions (SBIs) and elevated inversions (ELIs) in the atmospheric layer up to 3000 m. In the case of SBIs, this layer extended directly from the ground level to an altitude above which the air temperature decreases with altitude, whereas for ELIs, which have a base above ground level, only the lowermost inversion layer was taken into consideration. The results of the monthly and seasonal variations in the selected parameters for air temperature inversions (thickness—ΔZ, strength—ΔT, base—ZB) were analysed separately at night-time (00 UTC) and daytime (12 UTC). The thermal structure of the boundary layer up to 3000 m was primarily determined by ELIs, which occurred at a frequency of approximately 70% at both times during the 24-h period. The SBIs showed a pronounced temporal structure that occurred every second night throughout the year and from April to September, with a frequency similar to that of the ELI (approximately 60%). The worst vertical air exchange conditions, which resulted from the simultaneous occurrence of SBIs and ELIs, were found in 30% of nights from April to October. Elevated inversions generally formed in a layer from approximately 820 to 1200 m, which was the lowermost ELI in winter and the highest ELI in summer; however, in all seasons, the lowest base height was characteristic of daytime inversions. Both surface-based and elevated inversion layers were distinguished by comparable thicknesses, particularly for those occurring at night-time (generally within the range of 150-200 m). From November to March, greater thicknesses were identified in ELIs with lower occurrences, whereas SBIs were identified in the remaining months of the year.

  14. First metatarsophalangeal joint motion in Homo sapiens: theoretical association of two-axis kinematics and specific morphometrics.

    PubMed

    Durrant, Michael N; McElroy, Tucker; Durrant, Lara

    2012-01-01

    The metatarsal head and proximal phalanx exhibit considerable asymmetry in their shape and geometry, but there is little documentation in the literature regarding the prevalence of structural characteristics that occur in a given population. Although there is a considerable volume of in vivo and in vitro experiments demonstrating first metatarsal inversion around its longitudinal axis with dorsiflexion, little is known regarding the applicability of specific morphometrics to these motions. Nine distinctive osseous characteristics in the metatarsal head and phalanx were selected based on their location, geometry, and perceived functional relationship to previous studies describing metatarsal motion as inversion with dorsiflexion. The prevalences of the chosen characteristics were determined in a cohort of 21 randomly selected skeletal specimens, 19 of which were provided by the anatomical preparation office at the University of California, San Diego, and two of which were in the possession of one of us (M.D.). The frequency of occurrence of each selected morphological characteristic in this sample and the relevant summary statistics confirm a strong association between the selected features and a conceptual two-axis kinematic model of the metatarsophalangeal joint. The selected morphometrics are consistent with inversion of the metatarsal around its longitudinal axis as it dorsiflexes.

  15. The ZH ratio Analysis of Global Seismic Data

    NASA Astrophysics Data System (ADS)

    Yano, T.; Shikato, S.; Rivera, L.; Tanimoto, T.

    2007-12-01

    The ZH ratio, the ratio of vertical to horizontal component of the fundamental Rayleigh wave as a function of frequency, is an alternative approach to phase/group velocity analysis for constructing the S-wave velocity structure. In this study, teleseismic Rayleigh wave data for the frequency range between 0.004Hz to 0.04Hz is used to investigate the interior structure. We have analyzed most of the GEOSCOPE network data and some IRIS GSN stations using a technique developed by Tanimoto and Rivera (2007). Stable estimates of the ZH ratios were obtained for the frequency range for most stations. We have performed the inversion of the measured ZH ratios for the structure in the crust and mantle by using nonlinear iterative scheme. The depth sensitivity kernels for inversion are numerically calculated. Depth sensitivity of the lowest frequency extends to depths beyond 500 km but the sensitivity of the overall data for the frequency band extends down to about 300km. We found that an appropriate selection of an initial model, particularly the depth of Mohorovicic discontinuity, is important for this inversion. The inversion result depends on the initial model and turned out to be non-unique. We have constructed the initial model from the CRUST 2.0. Inversion with equal weighting to each data point tends to reduce variance of certain frequency range only. Therefore, we have developed a scheme to increase weighting to data points that do not fit well after the fifth iteration. This occurs more often for low frequency range, 0.004-0.007Hz. After fitting the lower frequency region, the low velocity zone around a depth of 100km is observed under some stations such as KIP (Kipapa, Hawaii) and ATD (Arta Cave, Djibouti). We have also carried out an analysis on the resolving power of data by examining the eigenvalues-eigenvectors of the least-squares problem. Unfortunately, the normal matrix usually has 1-2 very large eigenvalues, followed by much smaller eigenvalues. The third one is often an order of magnitude smaller. The largest eigenvalue is always dominated by an eigenfunction that has the peak at the surface. It indicates that the ZH ratio is sensitive to shallow structure but it has limited form in resolving power for underlying structure. We will report on the details on the resolving capabilities of the ZH ratios.

  16. Frequency and time domain three-dimensional inversion of electromagnetic data for a grounded-wire source

    NASA Astrophysics Data System (ADS)

    Sasaki, Yutaka; Yi, Myeong-Jong; Choi, Jihyang; Son, Jeong-Sul

    2015-01-01

    We present frequency- and time-domain three-dimensional (3-D) inversion approaches that can be applied to transient electromagnetic (TEM) data from a grounded-wire source using a PC. In the direct time-domain approach, the forward solution and sensitivity were obtained in the frequency domain using a finite-difference technique, and the frequency response was then Fourier-transformed using a digital filter technique. In the frequency-domain approach, TEM data were Fourier-transformed using a smooth-spectrum inversion method, and the recovered frequency response was then inverted. The synthetic examples show that for the time derivative of magnetic field, frequency-domain inversion of TEM data performs almost as well as time-domain inversion, with a significant reduction in computational time. In our synthetic studies, we also compared the resolution capabilities of the ground and airborne TEM and controlled-source audio-frequency magnetotelluric (CSAMT) data resulting from a common grounded wire. An airborne TEM survey at 200-m elevation achieved a resolution for buried conductors almost comparable to that of the ground TEM method. It is also shown that the inversion of CSAMT data was able to detect a 3-D resistivity structure better than the TEM inversion, suggesting an advantage of electric-field measurements over magnetic-field-only measurements.

  17. Functional Impact and Evolution of a Novel Human Polymorphic Inversion That Disrupts a Gene and Creates a Fusion Transcript

    PubMed Central

    Puig, Marta; Castellano, David; Pantano, Lorena; Giner-Delgado, Carla; Izquierdo, David; Gayà-Vidal, Magdalena; Lucas-Lledó, José Ignacio; Esko, Tõnu; Terao, Chikashi; Matsuda, Fumihiko; Cáceres, Mario

    2015-01-01

    Despite many years of study into inversions, very little is known about their functional consequences, especially in humans. A common hypothesis is that the selective value of inversions stems in part from their effects on nearby genes, although evidence of this in natural populations is almost nonexistent. Here we present a global analysis of a new 415-kb polymorphic inversion that is among the longest ones found in humans and is the first with clear position effects. This inversion is located in chromosome 19 and has been generated by non-homologous end joining between blocks of transposable elements with low identity. PCR genotyping in 541 individuals from eight different human populations allowed the detection of tag SNPs and inversion genotyping in multiple populations worldwide, showing that the inverted allele is mainly found in East Asia with an average frequency of 4.7%. Interestingly, one of the breakpoints disrupts the transcription factor gene ZNF257, causing a significant reduction in the total expression level of this gene in lymphoblastoid cell lines. RNA-Seq analysis of the effects of this expression change in standard homozygotes and inversion heterozygotes revealed distinct expression patterns that were validated by quantitative RT-PCR. Moreover, we have found a new fusion transcript that is generated exclusively from inverted chromosomes around one of the breakpoints. Finally, by the analysis of the associated nucleotide variation, we have estimated that the inversion was generated ~40,000–50,000 years ago and, while a neutral evolution cannot be ruled out, its current frequencies are more consistent with those expected for a deleterious variant, although no significant association with phenotypic traits has been found so far. PMID:26427027

  18. Functional Impact and Evolution of a Novel Human Polymorphic Inversion That Disrupts a Gene and Creates a Fusion Transcript.

    PubMed

    Puig, Marta; Castellano, David; Pantano, Lorena; Giner-Delgado, Carla; Izquierdo, David; Gayà-Vidal, Magdalena; Lucas-Lledó, José Ignacio; Esko, Tõnu; Terao, Chikashi; Matsuda, Fumihiko; Cáceres, Mario

    2015-10-01

    Despite many years of study into inversions, very little is known about their functional consequences, especially in humans. A common hypothesis is that the selective value of inversions stems in part from their effects on nearby genes, although evidence of this in natural populations is almost nonexistent. Here we present a global analysis of a new 415-kb polymorphic inversion that is among the longest ones found in humans and is the first with clear position effects. This inversion is located in chromosome 19 and has been generated by non-homologous end joining between blocks of transposable elements with low identity. PCR genotyping in 541 individuals from eight different human populations allowed the detection of tag SNPs and inversion genotyping in multiple populations worldwide, showing that the inverted allele is mainly found in East Asia with an average frequency of 4.7%. Interestingly, one of the breakpoints disrupts the transcription factor gene ZNF257, causing a significant reduction in the total expression level of this gene in lymphoblastoid cell lines. RNA-Seq analysis of the effects of this expression change in standard homozygotes and inversion heterozygotes revealed distinct expression patterns that were validated by quantitative RT-PCR. Moreover, we have found a new fusion transcript that is generated exclusively from inverted chromosomes around one of the breakpoints. Finally, by the analysis of the associated nucleotide variation, we have estimated that the inversion was generated ~40,000-50,000 years ago and, while a neutral evolution cannot be ruled out, its current frequencies are more consistent with those expected for a deleterious variant, although no significant association with phenotypic traits has been found so far.

  19. Inversion climatology at San Jose, California

    NASA Technical Reports Server (NTRS)

    Morgan, T.; Bornstein, R. D.

    1977-01-01

    Month-to-month variations in the early morning surface-based and near-noon elevated inversions at San Jose, Calif., were determined from slow rise radiosondes launched during a four-year period. A high frequency of shallow, radiative, surface-based inversions were found in winter during the early morning hours, while during the same period in summer, a low frequency of deeper based inversions arose from a combination of radiative and subsidence processes. The frequency of elevated inversions in the hours near noon was lowest during fall and spring, while inversion bases were highest and thicknesses least during these periods.

  20. The Evolution of Genome Structure by Natural and Sexual Selection.

    PubMed

    Kirkpatrick, Mark

    2017-01-01

    Progress on understanding how genome structure evolves is accelerating with the arrival of new genomic, comparative, and theoretical approaches. This article reviews progress in understanding how chromosome inversions and sex chromosomes evolve, and how their evolution affects species' ecology. Analyses of clines in inversion frequencies in flies and mosquitoes imply strong local adaptation, and roles for both over- and under dominant selection. Those results are consistent with the hypothesis that inversions become established when they capture locally adapted alleles. Inversions can carry alleles that are beneficial to closely related species, causing them to introgress following hybridization. Models show that this "adaptive cassette" scenario can trigger large range expansions, as recently happened in malaria mosquitoes. Sex chromosomes are the most rapidly evolving genome regions of some taxa. Sexually antagonistic selection may be the key force driving transitions of sex determination between different pairs of chromosomes and between XY and ZW systems. Fusions between sex-chromosomes and autosomes most often involve the Y chromosome, a pattern that can be explained if fusions are mildly deleterious and fix by drift. Sexually antagonistic selection is one of several hypotheses to explain the recent discovery that the sex determination system has strong effects on the adult sex ratios of tetrapods. The emerging view of how genome structure evolves invokes a much richer constellation of forces than was envisioned during the Golden Age of research on Drosophila karyotypes. © The American Genetic Association 2016. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  1. A Joint Method of Envelope Inversion Combined with Hybrid-domain Full Waveform Inversion

    NASA Astrophysics Data System (ADS)

    CUI, C.; Hou, W.

    2017-12-01

    Full waveform inversion (FWI) aims to construct high-precision subsurface models by fully using the information in seismic records, including amplitude, travel time, phase and so on. However, high non-linearity and the absence of low frequency information in seismic data lead to the well-known cycle skipping problem and make inversion easily fall into local minima. In addition, those 3D inversion methods that are based on acoustic approximation ignore the elastic effects in real seismic field, and make inversion harder. As a result, the accuracy of final inversion results highly relies on the quality of initial model. In order to improve stability and quality of inversion results, multi-scale inversion that reconstructs subsurface model from low to high frequency are applied. But, the absence of very low frequencies (< 3Hz) in field data is still bottleneck in the FWI. By extracting ultra low-frequency data from field data, envelope inversion is able to recover low wavenumber model with a demodulation operator (envelope operator), though the low frequency data does not really exist in field data. To improve the efficiency and viability of the inversion, in this study, we proposed a joint method of envelope inversion combined with hybrid-domain FWI. First, we developed 3D elastic envelope inversion, and the misfit function and the corresponding gradient operator were derived. Then we performed hybrid-domain FWI with envelope inversion result as initial model which provides low wavenumber component of model. Here, forward modeling is implemented in the time domain and inversion in the frequency domain. To accelerate the inversion, we adopt CPU/GPU heterogeneous computing techniques. There were two levels of parallelism. In the first level, the inversion tasks are decomposed and assigned to each computation node by shot number. In the second level, GPU multithreaded programming is used for the computation tasks in each node, including forward modeling, envelope extraction, DFT (discrete Fourier transform) calculation and gradients calculation. Numerical tests demonstrated that the combined envelope inversion + hybrid-domain FWI could obtain much faithful and accurate result than conventional hybrid-domain FWI. The CPU/GPU heterogeneous parallel computation could improve the performance speed.

  2. Embedding Term Similarity and Inverse Document Frequency into a Logical Model of Information Retrieval.

    ERIC Educational Resources Information Center

    Losada, David E.; Barreiro, Alvaro

    2003-01-01

    Proposes an approach to incorporate term similarity and inverse document frequency into a logical model of information retrieval. Highlights include document representation and matching; incorporating term similarity into the measure of distance; new algorithms for implementation; inverse document frequency; and logical versus classical models of…

  3. A sex-chromosome inversion causes strong overdominance for sperm traits that affect siring success.

    PubMed

    Knief, Ulrich; Forstmeier, Wolfgang; Pei, Yifan; Ihle, Malika; Wang, Daiping; Martin, Katrin; Opatová, Pavlína; Albrechtová, Jana; Wittig, Michael; Franke, Andre; Albrecht, Tomáš; Kempenaers, Bart

    2017-08-01

    Male reproductive success depends on the competitive ability of sperm to fertilize the ova, which should lead to strong selection on sperm characteristics. This raises the question of how heritable variation in sperm traits is maintained. Here we show that in zebra finches (Taeniopygia guttata) nearly half of the variance in sperm morphology is explained by an inversion on the Z chromosome with a 40% allele frequency in the wild. The sperm of males that are heterozygous for the inversion had the longest midpieces and the highest velocity. Furthermore, such males achieved the highest fertility and the highest siring success, both within-pair and extra-pair. Males homozygous for the derived allele show detrimental sperm characteristics and the lowest siring success. Our results suggest heterozygote advantage as the mechanism that maintains the inversion polymorphism and hence variance in sperm design and in fitness.

  4. Full waveform inversion using a decomposed single frequency component from a spectrogram

    NASA Astrophysics Data System (ADS)

    Ha, Jiho; Kim, Seongpil; Koo, Namhyung; Kim, Young-Ju; Woo, Nam-Sub; Han, Sang-Mok; Chung, Wookeen; Shin, Sungryul; Shin, Changsoo; Lee, Jaejoon

    2018-06-01

    Although many full waveform inversion methods have been developed to construct velocity models of subsurface, various approaches have been presented to obtain an inversion result with long-wavelength features even though seismic data lacking low-frequency components were used. In this study, a new full waveform inversion algorithm was proposed to recover a long-wavelength velocity model that reflects the inherent characteristics of each frequency component of seismic data using a single-frequency component decomposed from the spectrogram. We utilized the wavelet transform method to obtain the spectrogram, and the decomposed signal from the spectrogram was used as transformed data. The Gauss-Newton method with the diagonal elements of an approximate Hessian matrix was used to update the model parameters at each iteration. Based on the results of time-frequency analysis in the spectrogram, numerical tests with some decomposed frequency components were performed using a modified SEG/EAGE salt dome (A-A‧) line to demonstrate the feasibility of the proposed inversion algorithm. This demonstrated that a reasonable inverted velocity model with long-wavelength structures can be obtained using a single frequency component. It was also confirmed that when strong noise occurs in part of the frequency band, it is feasible to obtain a long-wavelength velocity model from the noise data with a frequency component that is less affected by the noise. Finally, it was confirmed that the results obtained from the spectrogram inversion can be used as an initial velocity model in conventional inversion methods.

  5. Parallel Evolution of Cold Tolerance within Drosophila melanogaster

    PubMed Central

    Braun, Dylan T.; Lack, Justin B.

    2017-01-01

    Drosophila melanogaster originated in tropical Africa before expanding into strikingly different temperate climates in Eurasia and beyond. Here, we find elevated cold tolerance in three distinct geographic regions: beyond the well-studied non-African case, we show that populations from the highlands of Ethiopia and South Africa have significantly increased cold tolerance as well. We observe greater cold tolerance in outbred versus inbred flies, but only in populations with higher inversion frequencies. Each cold-adapted population shows lower inversion frequencies than a closely-related warm-adapted population, suggesting that inversion frequencies may decrease with altitude in addition to latitude. Using the FST-based “Population Branch Excess” statistic (PBE), we found only limited evidence for parallel genetic differentiation at the scale of ∼4 kb windows, specifically between Ethiopian and South African cold-adapted populations. And yet, when we looked for single nucleotide polymorphisms (SNPs) with codirectional frequency change in two or three cold-adapted populations, strong genomic enrichments were observed from all comparisons. These findings could reflect an important role for selection on standing genetic variation leading to “soft sweeps”. One SNP showed sufficient codirectional frequency change in all cold-adapted populations to achieve experiment-wide significance: an intronic variant in the synaptic gene Prosap. Another codirectional outlier SNP, at senseless-2, had a strong association with our cold trait measurements, but in the opposite direction as predicted. More generally, proteins involved in neurotransmission were enriched as potential targets of parallel adaptation. The ability to study cold tolerance evolution in a parallel framework will enhance this classic study system for climate adaptation. PMID:27777283

  6. A strategy for the application of frequency domain acoustic waveform tomography to marine Walkaway VSP data

    NASA Astrophysics Data System (ADS)

    Bouzidi, Y.; Takam Takougang, E. M.

    2016-12-01

    Two dimensional frequency domain acoustic waveform tomography was applied to walkaway VSP data from an oil field in a shallow water environment, offshore the United Arab Emirates, to form a high resolution velocity model of the subsurface around and away from the borehole. Five close parallel walkaway VSP lines were merged to form a 9 km line, with 1344 shots at 25 m shot interval and 4 m shot depth. Each line was recorded using a typical recording tool with 20 receivers at 15.1 m receiver intervals. The recording tool was deployed in a deviated borehole at different depths for each line (521-2742 m depth). Waveform tomography was performed following a specific inversion strategy to mitigate non-linearity. Three parameters were critical for the success of the inversion: the starting model obtained from traveltime tomography, the preconditioning of the input data used for amplitudes correction to remove of shear waves and noise, and a judicious selection of the time damping constant τ to suppress late arrivals in the Laplace-Fourier domain. Several values of the time damping constant were tested, and 2 values, 0.5 s and 0.8 s that suppress waveforms arriving after 1.2 s and 2 s respectively, were retained. The inversion was performed in 2 stages, with frequencies ranging from 5 Hz to 40 Hz. The values of the time damping term τ = 0.5 s and τ = 0.8 s were used in sequence for the frequencies 5-25 Hz, and τ = 0.8 s was used for the frequencies 25-40 Hz. A group of 5 frequencies at 0.5 Hz intervals were used and 6 iterations were performed. A velocity model that generally correlates well with the sonic log and estimated velocities from normal incidence VSP was obtained. The results confirmed the success of the inversion strategy. The velocity model shows zones with anomalous low velocities below 2000 m depth that correlate with known locations of hydrocarbons reservoirs. with known locations of hydrocarbon reservoirs. However, between 500 m and 1200 m depth, the velocity model appears to be slightly underestimated, which can be explained by possible elastic effects and out-of-plane structures not considered during the inversion. This result shows that acoustic waveform tomography can be successfully applied to walkaway VSP data when a good preconditioning of the input data and inversion strategy are used.

  7. Age-related change of the secretory flow of pancreatic juice in the main pancreatic duct: evaluation with cine-dynamic MRCP using spatially selective inversion recovery pulse.

    PubMed

    Torigoe, Teruyuki; Ito, Katsuyoshi; Yamamoto, Akira; Kanki, Akihiko; Yasokawa, Kazuya; Tamada, Tsutomu; Yoshida, Koji

    2014-05-01

    The purpose of this study is to evaluate age-related changes in the secretory flow of pancreatic juice in the main pancreatic duct noninvasively by means of nonpharmacologic cine-dynamic MRCP using spatially selective inversion recovery (IR) pulse. Fifty-three subjects without a history of pancreatic disease were included. Four-second breath-hold MRCP using spatially selective IR pulse was performed every 15 seconds during 5 minutes (acquiring a total of 20 images) in cine-dynamic fashion. The secretion grade was classified into five grades by the distance of pancreatic juice inflow within the tagged area. The mean secretion grade and the frequency of secretion in cine-dynamic MRCP were compared among three age-range groups (group 1, < 40 years; group 2, 40-70 years; and group 3, > 70 years). Statistical analysis was performed using Spearman rank correlation coefficient and Kruskal-Wallis and Mann-Whitney U tests. The secretion grade and the frequency of secretion were significantly reduced with aging (r = -0.77, p < 0.001; and r = -0.74, p < 0.001, respectively). The mean secretion grade and the frequency of secretion were significantly lower in group 3 than in group 2 (mean grade, 0.36 vs 1.48, p = 0.001; and 4.8 vs 11.9 times, p = 0.001) and were lower in group 2 than in group 1 (mean grade, 1.48 vs 2.48, p < 0.001; and 11.9 vs 16.2 times, p = 0.011). Cine-dynamic MRCP using spatially selective IR pulse was able to show the age-related decrease of the secretory flow of pancreatic juice in the main pancreatic duct visually and noninvasively.

  8. Simultaneous Planck , Swift , and Fermi observations of X-ray and γ -ray selected blazars

    DOE PAGES

    Giommi, P.; Polenta, G.; Lähteenmäki, A.; ...

    2012-05-22

    We present simultaneous Planck, Swift, Fermi, and ground-based data for 105 blazars belonging to three samples with flux limits in the soft X-ray, hard X-ray, and γ-ray bands, with additional 5GHz flux-density limits to ensure a good probability of a Planck detection. We compare our results to those of a companion paper presenting simultaneous Planck and multi-frequency observations of 104 radio-loud northern active galactic nuclei selected at radio frequencies. While we confirm several previous results, our unique data set allows us to demonstrate that the selection method strongly influences the results, producing biases that cannot be ignored. Almost all themore » BL Lac objects have been detected by the Fermi Large AreaTelescope (LAT), whereas 30% to 40% of the flat-spectrum radio quasars (FSRQs) in the radio, soft X-ray, and hard X-ray selected samples are still below the γ-ray detection limit even after integrating 27 months of Fermi-LAT data. The radio to sub-millimetre spectral slope of blazars is quite flat, with >α> ~ 0 up to about 70GHz, above which it steepens to ~ -0.65. The BL Lacs have significantly flatter spectra than FSRQs at higher frequencies. The distribution of the rest-frame synchrotron peak frequency (ν peak S) in the spectral energy distribution (SED) of FSRQs is the same in all the blazar samples with peak S> = 10 13.1 ± 0.1 Hz, while the mean inverse Compton peak frequency, >ν peak IC>, ranges from 1021 to 1022 Hz. The distributions of ν peak S and ν peak IC of BL Lacs are much broader and are shifted to higher energies than those of FSRQs; their shapes strongly depend on the selection method. The Compton dominance of blazars, defined as the ratio of the inverse Compton to synchrotron peak luminosities, ranges from less than 0.2 to nearly 100, with only FSRQs reaching values larger than about 3. Its distribution is broad and depends strongly on the selection method, with γ-ray selected blazars peaking at ~7 or more, and radio-selected blazars at values close to 1, thus implying that the common assumption that the blazar power budget is largely dominated by high-energy emission is a selection effect. A comparison of our multi-frequency data with theoretical predictions shows that simple homogeneous SSC models cannot explain the simultaneous SEDs of most of the γ-ray detected blazars in all samples. The SED of the blazars that were not detected by Fermi-LAT may instead be consistent with SSC emission. Our data challenge the correlation between bolometric luminosity and ν peak S predicted by the blazar sequence.« less

  9. Harmonic generation with a dual frequency pulse.

    PubMed

    Keravnou, Christina P; Averkiou, Michalakis A

    2014-05-01

    Nonlinear imaging was implemented in commercial ultrasound systems over the last 15 years offering major advantages in many clinical applications. In this work, pulsing schemes coupled with a dual frequency pulse are presented. The pulsing schemes considered were pulse inversion, power modulation, and power modulated pulse inversion. The pulse contains a fundamental frequency f and a specified amount of its second harmonic 2f. The advantages and limitations of this method were evaluated with both acoustic measurements of harmonic generation and theoretical simulations based on the KZK equation. The use of two frequencies in a pulse results in the generation of the sum and difference frequency components in addition to the other harmonic components. While with single frequency pulses, only power modulation and power modulated pulse inversion contained odd harmonic components, with the dual frequency pulse, pulse inversion now also contains odd harmonic components.

  10. Bayesian linearized amplitude-versus-frequency inversion for quality factor and its application

    NASA Astrophysics Data System (ADS)

    Yang, Xinchao; Teng, Long; Li, Jingnan; Cheng, Jiubing

    2018-06-01

    We propose a straightforward attenuation inversion method by utilizing the amplitude-versus-frequency (AVF) characteristics of seismic data. A new linearized approximation equation of the angle and frequency dependent reflectivity in viscoelastic media is derived. We then use the presented equation to implement the Bayesian linear AVF inversion. The inversion result includes not only P-wave and S-wave velocities, and densities, but also P-wave and S-wave quality factors. Synthetic tests show that the AVF inversion surpasses the AVA inversion for quality factor estimation. However, a higher signal noise ratio (SNR) of data is necessary for the AVF inversion. To show its feasibility, we apply both the new Bayesian AVF inversion and conventional AVA inversion to a tight gas reservoir data in Sichuan Basin in China. Considering the SNR of the field data, a combination of AVF inversion for attenuation parameters and AVA inversion for elastic parameters is recommended. The result reveals that attenuation estimations could serve as a useful complement in combination with the AVA inversion results for the detection of tight gas reservoirs.

  11. Micro-Doppler Signal Time-Frequency Algorithm Based on STFRFT.

    PubMed

    Pang, Cunsuo; Han, Yan; Hou, Huiling; Liu, Shengheng; Zhang, Nan

    2016-09-24

    This paper proposes a time-frequency algorithm based on short-time fractional order Fourier transformation (STFRFT) for identification of a complicated movement targets. This algorithm, consisting of a STFRFT order-changing and quick selection method, is effective in reducing the computation load. A multi-order STFRFT time-frequency algorithm is also developed that makes use of the time-frequency feature of each micro-Doppler component signal. This algorithm improves the estimation accuracy of time-frequency curve fitting through multi-order matching. Finally, experiment data were used to demonstrate STFRFT's performance in micro-Doppler time-frequency analysis. The results validated the higher estimate accuracy of the proposed algorithm. It may be applied to an LFM (Linear frequency modulated) pulse radar, SAR (Synthetic aperture radar), or ISAR (Inverse synthetic aperture radar), for improving the probability of target recognition.

  12. Noise spectroscopy as an equilibrium analysis tool for highly sensitive electrical biosensing

    NASA Astrophysics Data System (ADS)

    Guo, Qiushi; Kong, Tao; Su, Ruigong; Zhang, Qi; Cheng, Guosheng

    2012-08-01

    We demonstrate an approach for highly sensitive bio-detection based on silicon nanowire field-effect transistors by employing low frequency noise spectroscopy analysis. The inverse of noise amplitude of the device exhibits an enhanced gate coupling effect in strong inversion regime when measured in buffer solution than that in air. The approach was further validated by the detection of cardiac troponin I of 0.23 ng/ml in fetal bovine serum, in which 2 orders of change in noise amplitude was characterized. The selectivity of the proposed approach was also assessed by the addition of 10 μg/ml bovine serum albumin solution.

  13. Low-frequency centroid-moment-tensor inversion from superconducting-gravimeter data: The effect of seismic attenuation

    NASA Astrophysics Data System (ADS)

    Zábranová, Eliška; Matyska, Ctirad

    2014-10-01

    After the 2010 Maule and 2011 Tohoku earthquakes the spheroidal modes up to 1 mHz were clearly registered by the Global Geodynamic Project (GGP) network of superconducting gravimeters (SG). Fundamental parameters in synthetic calculations of the signals are the quality factors of the modes. We study the role of their uncertainties in the centroid-moment-tensor (CMT) inversions. First, we have inverted the SG data from selected GGP stations to jointly determine the quality factors of these normal modes and the three low-frequency CMT components, Mrr,(Mϑϑ-Mφφ)/2 and Mϑφ, that generate the observed SG signal. We have used several-days-long records to minimize the trade-off between the quality factors and the CMT but it was not eliminated completely. We have also inverted each record separately to get error estimates of the obtained parameters. Consequently, we have employed the GGP records of 60-h lengths for several published modal-quality-factor sets and inverted only the same three CMT components. The obtained CMT tensors are close to the solution from the joint Q-CMT inversion of longer records and resulting variability of the CMT components is smaller than differences among routine agency solutions. Reliable low-frequency CMT components can thus be obtained for any quality factors from the studied sets.

  14. Multi-Focus Image Fusion Based on NSCT and NSST

    NASA Astrophysics Data System (ADS)

    Moonon, Altan-Ulzii; Hu, Jianwen

    2015-12-01

    In this paper, a multi-focus image fusion algorithm based on the nonsubsampled contourlet transform (NSCT) and the nonsubsampled shearlet transform (NSST) is proposed. The source images are first decomposed by the NSCT and NSST into low frequency coefficients and high frequency coefficients. Then, the average method is used to fuse low frequency coefficient of the NSCT. To obtain more accurate salience measurement, the high frequency coefficients of the NSST and NSCT are combined to measure salience. The high frequency coefficients of the NSCT with larger salience are selected as fused high frequency coefficients. Finally, the fused image is reconstructed by the inverse NSCT. We adopt three metrics (Q AB/F , Q e and Q w ) to evaluate the quality of fused images. The experimental results demonstrate that the proposed method outperforms other methods. It retains highly detailed edges and contours.

  15. Characterizing a porous road pavement using surface impedance measurement: a guided numerical inversion procedure.

    PubMed

    Benoit, Gaëlle; Heinkélé, Christophe; Gourdon, Emmanuel

    2013-12-01

    This paper deals with a numerical procedure to identify the acoustical parameters of road pavement from surface impedance measurements. This procedure comprises three steps. First, a suitable equivalent fluid model for the acoustical properties porous media is chosen, the variation ranges for the model parameters are set, and a sensitivity analysis for this model is performed. Second, this model is used in the parameter inversion process, which is performed with simulated annealing in a selected frequency range. Third, the sensitivity analysis and inversion process are repeated to estimate each parameter in turn. This approach is tested on data obtained for porous bituminous concrete and using the Zwikker and Kosten equivalent fluid model. This work provides a good foundation for the development of non-destructive in situ methods for the acoustical characterization of road pavements.

  16. Direct observation of inversion capacitance in p-type diamond MOS capacitors with an electron injection layer

    NASA Astrophysics Data System (ADS)

    Matsumoto, Tsubasa; Kato, Hiromitsu; Makino, Toshiharu; Ogura, Masahiko; Takeuchi, Daisuke; Yamasaki, Satoshi; Imura, Masataka; Ueda, Akihiro; Inokuma, Takao; Tokuda, Norio

    2018-04-01

    The electrical properties of Al2O3/p-type diamond (111) MOS capacitors were studied with the goal of furthering diamond-based semiconductor research. To confirm the formation of an inversion layer in the p-type diamond body, an n-type layer for use as a minority carrier injection layer was selectively deposited onto p-type diamond. To form the diamond MOS capacitors, Al2O3 was deposited onto OH-terminated diamond using atomic layer deposition. The MOS capacitor showed clear inversion capacitance at 10 Hz. The minority carrier injection from the n-type layer reached the inversion n-channel diamond MOS field-effect transistor (MOSFET). Using the high-low frequency capacitance method, the interface state density, D it, within an energy range of 0.1-0.5 eV from the valence band edge energy, E v, was estimated at (4-9) × 1012 cm-2 eV-1. However, the high D it near E v remains an obstacle to improving the field effect mobility for the inversion p-channel diamond MOSFET.

  17. Final Technical Report for "Applied Mathematics Research: Simulation Based Optimization and Application to Electromagnetic Inverse Problems"

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Haber, Eldad

    2014-03-17

    The focus of research was: Developing adaptive mesh for the solution of Maxwell's equations; Developing a parallel framework for time dependent inverse Maxwell's equations; Developing multilevel methods for optimization problems with inequality constraints; A new inversion code for inverse Maxwell's equations in the 0th frequency (DC resistivity); A new inversion code for inverse Maxwell's equations in low frequency regime. Although the research concentrated on electromagnetic forward and in- verse problems the results of the research was applied to the problem of image registration.

  18. A Common 16p11.2 Inversion Underlies the Joint Susceptibility to Asthma and Obesity

    PubMed Central

    González, Juan R.; Cáceres, Alejandro; Esko, Tonu; Cuscó, Ivon; Puig, Marta; Esnaola, Mikel; Reina, Judith; Siroux, Valerie; Bouzigon, Emmanuelle; Nadif, Rachel; Reinmaa, Eva; Milani, Lili; Bustamante, Mariona; Jarvis, Deborah; Antó, Josep M.; Sunyer, Jordi; Demenais, Florence; Kogevinas, Manolis; Metspalu, Andres; Cáceres, Mario; Pérez-Jurado, Luis A.

    2014-01-01

    The prevalence of asthma and obesity is increasing worldwide, and obesity is a well-documented risk factor for asthma. The mechanisms underlying this association and parallel time trends remain largely unknown but genetic factors may be involved. Here, we report on a common ∼0.45 Mb genomic inversion at 16p11.2 that can be accurately genotyped via SNP array data. We show that the inversion allele protects against the joint occurrence of asthma and obesity in five large independent studies (combined sample size of 317 cases and 543 controls drawn from a total of 5,809 samples; combined OR = 0.48, p = 5.5 × 10−6). Allele frequencies show remarkable worldwide population stratification, ranging from 10% in East Africa to 49% in Northern Europe, consistent with discordant and extreme genetic drifts or adaptive selections after human migration out of Africa. Inversion alleles strongly correlate with expression levels of neighboring genes, especially TUFM (p = 3.0 × 10−40) that encodes a mitochondrial protein regulator of energy balance and inhibitor of type 1 interferon, and other candidates for asthma (IL27) and obesity (APOB48R and SH2B1). Therefore, by affecting gene expression, the ∼0.45 Mb 16p11.2 inversion provides a genetic basis for the joint susceptibility to asthma and obesity, with a population attributable risk of 39.7%. Differential mitochondrial function and basal energy balance of inversion alleles might also underlie the potential selection signature that led to their uneven distribution in world populations. PMID:24560518

  19. Inversion of the resonance line of Sr/+/ produced by optically pumping Sr atoms

    NASA Technical Reports Server (NTRS)

    Green, W. R.; Falcone, R. W.

    1978-01-01

    A description is presented of an experiment which demonstrates the selective production of excited-state ions by an optical absorption from neutrals. An inversion on the resonance line of Sr(+) was produced by laser excitation of a two-electron transition, followed by ionization of one of the excited electrons by the same laser. A pulsed, mode-locked laser operating at 2680 A was used to excite atoms from the Sr ground level. The same laser then ionized the excited atoms. The 2680-A pump beam was generated by frequency doubling the output of a synchronously pumped mode-locked dye laser in a KDP crystal. It is pointed out that the reported results are significant for the construction of vacuum-ultraviolet and X-ray lasers. Many of the proposed methods for making such lasers depend on the selective production of excited-state ions.

  20. Joint time/frequency-domain inversion of reflection data for seabed geoacoustic profiles and uncertainties.

    PubMed

    Dettmer, Jan; Dosso, Stan E; Holland, Charles W

    2008-03-01

    This paper develops a joint time/frequency-domain inversion for high-resolution single-bounce reflection data, with the potential to resolve fine-scale profiles of sediment velocity, density, and attenuation over small seafloor footprints (approximately 100 m). The approach utilizes sequential Bayesian inversion of time- and frequency-domain reflection data, employing ray-tracing inversion for reflection travel times and a layer-packet stripping method for spherical-wave reflection-coefficient inversion. Posterior credibility intervals from the travel-time inversion are passed on as prior information to the reflection-coefficient inversion. Within the reflection-coefficient inversion, parameter information is passed from one layer packet inversion to the next in terms of marginal probability distributions rotated into principal components, providing an efficient approach to (partially) account for multi-dimensional parameter correlations with one-dimensional, numerical distributions. Quantitative geoacoustic parameter uncertainties are provided by a nonlinear Gibbs sampling approach employing full data error covariance estimation (including nonstationary effects) and accounting for possible biases in travel-time picks. Posterior examination of data residuals shows the importance of including data covariance estimates in the inversion. The joint inversion is applied to data collected on the Malta Plateau during the SCARAB98 experiment.

  1. Adaptive multi-step Full Waveform Inversion based on Waveform Mode Decomposition

    NASA Astrophysics Data System (ADS)

    Hu, Yong; Han, Liguo; Xu, Zhuo; Zhang, Fengjiao; Zeng, Jingwen

    2017-04-01

    Full Waveform Inversion (FWI) can be used to build high resolution velocity models, but there are still many challenges in seismic field data processing. The most difficult problem is about how to recover long-wavelength components of subsurface velocity models when seismic data is lacking of low frequency information and without long-offsets. To solve this problem, we propose to use Waveform Mode Decomposition (WMD) method to reconstruct low frequency information for FWI to obtain a smooth model, so that the initial model dependence of FWI can be reduced. In this paper, we use adjoint-state method to calculate the gradient for Waveform Mode Decomposition Full Waveform Inversion (WMDFWI). Through the illustrative numerical examples, we proved that the low frequency which is reconstructed by WMD method is very reliable. WMDFWI in combination with the adaptive multi-step inversion strategy can obtain more faithful and accurate final inversion results. Numerical examples show that even if the initial velocity model is far from the true model and lacking of low frequency information, we still can obtain good inversion results with WMD method. From numerical examples of anti-noise test, we see that the adaptive multi-step inversion strategy for WMDFWI has strong ability to resist Gaussian noise. WMD method is promising to be able to implement for the land seismic FWI, because it can reconstruct the low frequency information, lower the dominant frequency in the adjoint source, and has a strong ability to resist noise.

  2. Simultaneous Planck, Swift, and Fermi Observations of X-ray and Gamma-ray Selected Blazars

    NASA Technical Reports Server (NTRS)

    Giommi, P.; Polenta, G.; Laehteenmaeki, A.; Thompson, D. J.; Capalbi, M.; Cutini, S.; Gasparrini, D.; Gonzalez, Nuevo, J.; Leon-Tavares, J.; Lopez-Caniego, M.; hide

    2012-01-01

    We present simultaneous Planck, Swift, Fermi, and ground-based data for 105 blazars belonging to three samples with flux limits in the soft X-ray, hard X-ray, and gamma-ray bands, with additional 5 GHz flux-density limits to ensure a good probability of a Planck detection. We compare our results to those of a companion paper presenting simultaneous Planck and multi-frequency observations of 104 radio-loud northern active galactic nuclei selected at radio frequencies. While we confirm several previous results, our unique data set allows us to demonstrate that the selection method strongly influences the results, producing biases that cannot be ignored. Almost all the BL Lac objects have been detected by the Fermi Large Area Telescope (LAT), whereas 30% to 40% of the flat-spectrum radio quasars (FSRQs) in the radio, soft X-ray, and hard X-ray selected samples are still below the gamma-ray detection limit even after integrating 27 months of Fermi-LAT data. The radio to sub-millimetre spectral slope of blazars is quite flat, with (alpha) approx 0 up to about 70GHz, above which it steepens to (alpha) approx -0.65. The BL Lacs have significantly flatter spectra than FSRQs at higher frequencies. The distribution of the rest-frame synchrotron peak frequency (nu(sup s)(sub peak)) in the spectral energy distribution (SED) of FSRQs is the same in all the blazar samples with (nu(sup s)(sub peak)) = 10(exp 13.1 +/- 0.1) Hz, while the mean inverse Compton peak frequency, (nu(sup IC)(sub peak)), ranges from 10(exp 21) to 10(exp 22) Hz. The distributions of nu(sup s)(sub peak) and nu(sup IC)(sub peak) of BL Lacs are much broader and are shifted to higher energies than those of FSRQs; their shapes strongly depend on the selection method. The Compton dominance of blazars. defined as the ratio of the inverse Compton to synchrotron peak luminosities, ranges from less than 0.2 to nearly 100, with only FSRQs reaching values larger than about 3. Its distribution is broad and depends strongly on the selection method, with gamma-ray selected blazars peaking at approx 7 or more, and radio-selected blazars at values close to 1, thus implying that the common assumption that the blazar power budget is largely dominated by high-energy emission is a selection effect. A comparison of our multi-frequency data with theoretical predictions shows that simple homogeneous SSC models cannot explain the simultaneous SEDs of most of the gamma-ray detected blazars in all samples. The SED of the blazars that were not detected by FermiLAT may instead be consistent with SSC emission. Our data challenge the correlation between bolometric luminosity and nu(sup s)(sub peak) predicted by the blazar sequence.

  3. The Genetic Content of Chromosomal Inversions across a Wide Latitudinal Gradient

    PubMed Central

    Simões, Pedro; Calabria, Gemma; Picão-Osório, João; Balanyà, Joan; Pascual, Marta

    2012-01-01

    There is increasing evidence regarding the role of chromosomal inversions in relevant biological processes such as local adaptation and speciation. A classic example of the adaptive role of chromosomal polymorphisms is given by the clines of inversion frequencies in Drosophila subobscura, repeatable across continents. Nevertheless, not much is known about the molecular variation associated with these polymorphisms. We characterized the genetic content of ca. 600 individuals from nine European populations following a latitudinal gradient by analysing 19 microsatellite loci from two autosomes (J and U) and the sex chromosome (A), taking into account their chromosomal inversions. Our results clearly demonstrate the molecular genetic uniformity within a given chromosomal inversion across a large latitudinal gradient, particularly from Groningen (Netherlands) in the north to Málaga (Spain) in the south, experiencing highly diverse environmental conditions. This low genetic differentiation within the same gene arrangement across the nine European populations is consistent with the local adaptation hypothesis for th evolutionof chromosomal polymorphisms. We also show the effective role of chromosomal inversions in maintaining different genetic pools within these inverted genomic regions even in the presence of high gene flow. Inversions represent thus an important barrier to gene flux and can help maintain specific allelic combinations with positive effects on fitness. Consistent patterns of microsatellite allele-inversion linkage disequilibrium particularly in loci within inversions were also observed. Finally, we identified areas within inversions presenting clinal variation that might be under selection. PMID:23272126

  4. Four decades of inversion polymorphism in Drosophila pseudoobscura.

    PubMed Central

    Anderson, W W; Arnold, J; Baldwin, D G; Beckenbach, A T; Brown, C J; Bryant, S H; Coyne, J A; Harshman, L G; Heed, W B; Jeffery, D E

    1991-01-01

    We report data that continue the studies of Dobzhansky and others on the frequencies of third-chromosome inversions in natural populations of Drosophila pseudoobscura in North America. The common gene arrangements continue to be present in frequencies similar to those described four decades ago, and the broad geographic patterns also remain unchanged. There is only one pronounced trend over time: the increase in frequency of the Tree Line inversion in Pacific coast populations. PMID:1946458

  5. Wavelet-based 3-D inversion for frequency-domain airborne EM data

    NASA Astrophysics Data System (ADS)

    Liu, Yunhe; Farquharson, Colin G.; Yin, Changchun; Baranwal, Vikas C.

    2018-04-01

    In this paper, we propose a new wavelet-based 3-D inversion method for frequency-domain airborne electromagnetic (FDAEM) data. Instead of inverting the model in the space domain using a smoothing constraint, this new method recovers the model in the wavelet domain based on a sparsity constraint. In the wavelet domain, the model is represented by two types of coefficients, which contain both large- and fine-scale informations of the model, meaning the wavelet-domain inversion has inherent multiresolution. In order to accomplish a sparsity constraint, we minimize an L1-norm measure in the wavelet domain that mostly gives a sparse solution. The final inversion system is solved by an iteratively reweighted least-squares method. We investigate different orders of Daubechies wavelets to accomplish our inversion algorithm, and test them on synthetic frequency-domain AEM data set. The results show that higher order wavelets having larger vanishing moments and regularity can deliver a more stable inversion process and give better local resolution, while the lower order wavelets are simpler and less smooth, and thus capable of recovering sharp discontinuities if the model is simple. At last, we test this new inversion algorithm on a frequency-domain helicopter EM (HEM) field data set acquired in Byneset, Norway. Wavelet-based 3-D inversion of HEM data is compared to L2-norm-based 3-D inversion's result to further investigate the features of the new method.

  6. Advantages of the full-waveform inversion: real data example from the Polish Basin

    NASA Astrophysics Data System (ADS)

    Malinowski, M.; Operto, S.

    2006-12-01

    Modern acquisition techniques allow us to gather high-density seismic data even in case of crustal-scale investigations. In combination with increasing availability of computational resources (eg. PC clusters), this allow us to image the Earth's structure on much finer scale than offered by ray-theory based methods (like travel time tomography) by applying the full waveform inversion/tomography method (FWT). Recently, the FWT method was for the first time successfully applied to the real wide-aperture data: 100-km long OBS profile (Operto et al. 2006) and a 15-km long land profile (Operto et al. 2004, Ravaut et al., 2004). We present the results of the application of the FWT method to the GRUNDY 2003 experiment data, which is standing in between the scale of the mentioned datasets. This project was targeted at recognition of the pre-Zechstein strata within the Polish Basin. For a successful investigations relatively low-frequencies and wide-apertures were used. In the 50 by 10 km rectangular area ca. 800 RefTek 125 "Texan" stations with 4.5 Hz geophones were deployed, forming high-density central line (receiver spacing 100 m) and additional 4 parallel profiles. Previously the data were modelled using conventional methods: CDP processing and traveltime tomography. In order to utilise secondary arrivals, we used the frequency-domain FWT method of Pratt et al. (1998). The wide-aperture content of our data leads to a redundant wavenumber coverage which can be partially removed without loss of information by limiting the inversion to few frequencies only. The inversion proceeds by stepping from low to high frequencies and uses the model inferred for one component as the starting one for the next frequency. Before full waveform inversion, the data were preprocessed by QC editing, spectral deconvolution (whitening), bandpass filtering and muting in narrow window around the first arrival. Traveltime tomogram was choosen as the starting model for 2D waveform inversion. The model size was 50x10 km with 25 m FD grid step. We have selected 10 frequencies from 4 to 13 Hz. For each frequency 10 iterations were computed (on a Linux cluster). There is a clear improvement in resolution of the obtained tomographic images by exploiting the full wavefield. The model allows to predict also fairly well the observed seismograms and is consistent with both the geological horizons projected from industrial reflection profiles as well as check-shot velocity log. Benefits of FWT in application to our data seems to be clear: in one step, without the need for performing the forward raytracing modelling, we gained both the quasi-structural image (perturbational model) and the detailed velocity model. In this way we fully exploited the broad range of recorded offsets and reflection angles from pre- to postcritical ones for a successful imaging beneath the Zechstein strata.

  7. Nonresonant interaction of ultrashort electromagnetic pulses with multilevel quantum systems

    NASA Technical Reports Server (NTRS)

    Belenov, E.; Isakov, V.; Nazarkin, A.

    1994-01-01

    Some features of the excitation of multilevel quantum systems under the action of electromagnetic pulses which are shorter than the inverse frequency of interlevel transitions are considered. It is shown that the interaction is characterized by a specific type of selectivity which is not connected with the resonant absorption of radiation. The simplest three-level model displays the inverse population of upper levels. The effect of an ultrashort laser pulse on a multilevel molecule was regarded as an instant reception of the oscillation velocity by the oscillator and this approach showed an effective excitation and dissociation of the molecule. The estimations testify to the fact that these effects can be observed using modern femtosecond lasers.

  8. In vivo lactate and beta-hydroxybutyrate editing using a pure-phase refocusing pulse train.

    PubMed

    Shen, J; Novotny, E J; Rothman, D L

    1998-11-01

    A refocusing pulse train consisting of a semiselective refocusing pulse and a selective inversion pulse to obtain a pure-phase refocusing at the frequency of maximal excitation of the semiselective refocusing pulse is proposed and applied to in vivo lactate and beta-hydroxybutyrate editing using difference spectroscopy. It is shown, using both rotation matrix theory and phantom experiments, that the soft inversion pulse has to be halved to flank the semiselective pulse to obtain perfect refocusing and cancellation of interfering resonances. The editing method is used to obtain lactate and beta-hydroxybutyrate spectra from the occipital cortex of juvenile epilepsy patients before and after ketogenic diet treatment.

  9. Face-Evoked Steady-State Visual Potentials: Effects of Presentation Rate and Face Inversion

    PubMed Central

    Gruss, L. Forest; Wieser, Matthias J.; Schweinberger, Stefan R.; Keil, Andreas

    2012-01-01

    Face processing can be explored using electrophysiological methods. Research with event-related potentials has demonstrated the so-called face inversion effect, in which the N170 component is enhanced in amplitude and latency to inverted, compared to upright, faces. The present study explored the extent to which repetitive lower-level visual cortical engagement, reflected in flicker steady-state visual evoked potentials (ssVEPs), shows similar amplitude enhancement to face inversion. We also asked if inversion-related ssVEP modulation would be dependent on the stimulation rate at which upright and inverted faces were flickered. To this end, multiple tagging frequencies were used (5, 10, 15, and 20 Hz) across two studies (n = 21, n = 18). Results showed that amplitude enhancement of the ssVEP for inverted faces was found solely at higher stimulation frequencies (15 and 20 Hz). By contrast, lower frequency ssVEPs did not show this inversion effect. These findings suggest that stimulation frequency affects the sensitivity of ssVEPs to face inversion. PMID:23205009

  10. Full waveform inversion in the frequency domain using classified time-domain residual wavefields

    NASA Astrophysics Data System (ADS)

    Son, Woohyun; Koo, Nam-Hyung; Kim, Byoung-Yeop; Lee, Ho-Young; Joo, Yonghwan

    2017-04-01

    We perform the acoustic full waveform inversion in the frequency domain using residual wavefields that have been separated in the time domain. We sort the residual wavefields in the time domain according to the order of absolute amplitudes. Then, the residual wavefields are separated into several groups in the time domain. To analyze the characteristics of the residual wavefields, we compare the residual wavefields of conventional method with those of our residual separation method. From the residual analysis, the amplitude spectrum obtained from the trace before separation appears to have little energy at the lower frequency bands. However, the amplitude spectrum obtained from our strategy is regularized by the separation process, which means that the low-frequency components are emphasized. Therefore, our method helps to emphasize low-frequency components of residual wavefields. Then, we generate the frequency-domain residual wavefields by taking the Fourier transform of the separated time-domain residual wavefields. With these wavefields, we perform the gradient-based full waveform inversion in the frequency domain using back-propagation technique. Through a comparison of gradient directions, we confirm that our separation method can better describe the sub-salt image than the conventional approach. The proposed method is tested on the SEG/EAGE salt-dome model. The inversion results show that our algorithm is better than the conventional gradient based waveform inversion in the frequency domain, especially for deeper parts of the velocity model.

  11. When ottoman is easier than chair: an inverse frequency effect in jargon aphasia.

    PubMed

    Marshall, J; Pring, T; Chiat, S; Robson, J

    2001-02-01

    This paper presents evidence of an inverse frequency effect in jargon aphasia. The subject (JP) showed a pre-disposition for low frequency word production on a range of tasks, including picture naming, sentence completion and naming in categories. Her real word errors were also striking, in that these tended to be lower in frequency than the target. Reading data suggested that the inverse frequency effect was present only when production was semantically mediated. It was therefore hypothesised that the effect was at least partly due to the semantic characteristics of low frequency items. Some support for this was obtained from a comprehension task showing that JP's understanding of low frequency terms, which she often produced as errors, was superior to her understanding of high frequency terms. Possible explanations for these findings are considered.

  12. Frequency domain, waveform inversion of laboratory crosswell radar data

    USGS Publications Warehouse

    Ellefsen, Karl J.; Mazzella, Aldo T.; Horton, Robert J.; McKenna, Jason R.

    2010-01-01

    A new waveform inversion for crosswell radar is formulated in the frequency-domain for a 2.5D model. The inversion simulates radar waves using the vector Helmholtz equation for electromagnetic waves. The objective function is minimized using a backpropagation method suitable for a 2.5D model. The inversion is tested by processing crosswell radar data collected in a laboratory tank. The estimated model is consistent with the known electromagnetic properties of the tank. The formulation for the 2.5D model can be extended to inversions of acoustic and elastic data.

  13. Selection on Inversion Breakpoints Favors Proximity to Pairing Sensitive Sites in Drosophila melanogaster

    PubMed Central

    Corbett-Detig, Russell B.

    2016-01-01

    Chromosomal inversions are widespread among taxa, and have been implicated in a number of biological processes including adaptation, sex chromosome evolution, and segregation distortion. Consistent with selection favoring linkage between loci, it is well established that length is a selected trait of inversions. However, the factors that affect the distribution of inversion breakpoints remain poorly understood. “Sensitive sites” have been mapped on all euchromatic chromosome arms in Drosophila melanogaster, and may be a source of natural selection on inversion breakpoint positions. Briefly, sensitive sites are genomic regions wherein proximal structural rearrangements result in large reductions in local recombination rates in heterozygotes. Here, I show that breakpoints of common inversions are significantly more likely to lie within a cytological band containing a sensitive site than are breakpoints of rare inversions. Furthermore, common inversions for which neither breakpoint intersects a sensitive site are significantly longer than rare inversions, but common inversions whose breakpoints intersect a sensitive site show no evidence for increased length. I interpret these results to mean that selection favors inversions whose breakpoints disrupt synteny near to sensitive sites, possibly because these inversions suppress recombination in large genomic regions. To my knowledge this is the first evidence consistent with positive selection acting on inversion breakpoint positions. PMID:27343234

  14. Selection on Inversion Breakpoints Favors Proximity to Pairing Sensitive Sites in Drosophila melanogaster.

    PubMed

    Corbett-Detig, Russell B

    2016-09-01

    Chromosomal inversions are widespread among taxa, and have been implicated in a number of biological processes including adaptation, sex chromosome evolution, and segregation distortion. Consistent with selection favoring linkage between loci, it is well established that length is a selected trait of inversions. However, the factors that affect the distribution of inversion breakpoints remain poorly understood. "Sensitive sites" have been mapped on all euchromatic chromosome arms in Drosophila melanogaster, and may be a source of natural selection on inversion breakpoint positions. Briefly, sensitive sites are genomic regions wherein proximal structural rearrangements result in large reductions in local recombination rates in heterozygotes. Here, I show that breakpoints of common inversions are significantly more likely to lie within a cytological band containing a sensitive site than are breakpoints of rare inversions. Furthermore, common inversions for which neither breakpoint intersects a sensitive site are significantly longer than rare inversions, but common inversions whose breakpoints intersect a sensitive site show no evidence for increased length. I interpret these results to mean that selection favors inversions whose breakpoints disrupt synteny near to sensitive sites, possibly because these inversions suppress recombination in large genomic regions. To my knowledge this is the first evidence consistent with positive selection acting on inversion breakpoint positions. Copyright © 2016 by the Genetics Society of America.

  15. Semiautomatic approaches to account for 3-D distortion of the electric field from local, near-surface structures in 3-D resistivity inversions of 3-D regional magnetotelluric data

    USGS Publications Warehouse

    Rodriguez, Brian D.

    2017-03-31

    This report summarizes the results of three-dimensional (3-D) resistivity inversion simulations that were performed to account for local 3-D distortion of the electric field in the presence of 3-D regional structure, without any a priori information on the actual 3-D distribution of the known subsurface geology. The methodology used a 3-D geologic model to create a 3-D resistivity forward (“known”) model that depicted the subsurface resistivity structure expected for the input geologic configuration. The calculated magnetotelluric response of the modeled resistivity structure was assumed to represent observed magnetotelluric data and was subsequently used as input into a 3-D resistivity inverse model that used an iterative 3-D algorithm to estimate 3-D distortions without any a priori geologic information. A publicly available inversion code, WSINV3DMT, was used for all of the simulated inversions, initially using the default parameters, and subsequently using adjusted inversion parameters. A semiautomatic approach of accounting for the static shift using various selections of the highest frequencies and initial models was also tested. The resulting 3-D resistivity inversion simulation was compared to the “known” model and the results evaluated. The inversion approach that produced the lowest misfit to the various local 3-D distortions was an inversion that employed an initial model volume resistivity that was nearest to the maximum resistivities in the near-surface layer.

  16. Inversion of High Frequency Acoustic Data for Sediment Properties Needed for the Detection and Classification of UXOs

    DTIC Science & Technology

    2015-05-26

    FINAL REPORT Inversion of High Frequency Acoustic Data for Sediment Properties Needed for the Detection and Classification of UXOs SERDP...DOCUMENTATION PAGE Prescribed by ANSI Std. Z39.18 Form Approved OMB No. 0704-0188 The public reporting burden for this collection of information is...2015 Inversion of High Frequency Acoustic Data for Sediment Properties Needed for the Detection and Classification of UXO’s W912HQ-12-C-0049 MR

  17. A common 16p11.2 inversion underlies the joint susceptibility to asthma and obesity.

    PubMed

    González, Juan R; Cáceres, Alejandro; Esko, Tonu; Cuscó, Ivon; Puig, Marta; Esnaola, Mikel; Reina, Judith; Siroux, Valerie; Bouzigon, Emmanuelle; Nadif, Rachel; Reinmaa, Eva; Milani, Lili; Bustamante, Mariona; Jarvis, Deborah; Antó, Josep M; Sunyer, Jordi; Demenais, Florence; Kogevinas, Manolis; Metspalu, Andres; Cáceres, Mario; Pérez-Jurado, Luis A

    2014-03-06

    The prevalence of asthma and obesity is increasing worldwide, and obesity is a well-documented risk factor for asthma. The mechanisms underlying this association and parallel time trends remain largely unknown but genetic factors may be involved. Here, we report on a common ~0.45 Mb genomic inversion at 16p11.2 that can be accurately genotyped via SNP array data. We show that the inversion allele protects against the joint occurrence of asthma and obesity in five large independent studies (combined sample size of 317 cases and 543 controls drawn from a total of 5,809 samples; combined OR = 0.48, p = 5.5 × 10(-6)). Allele frequencies show remarkable worldwide population stratification, ranging from 10% in East Africa to 49% in Northern Europe, consistent with discordant and extreme genetic drifts or adaptive selections after human migration out of Africa. Inversion alleles strongly correlate with expression levels of neighboring genes, especially TUFM (p = 3.0 × 10(-40)) that encodes a mitochondrial protein regulator of energy balance and inhibitor of type 1 interferon, and other candidates for asthma (IL27) and obesity (APOB48R and SH2B1). Therefore, by affecting gene expression, the ~0.45 Mb 16p11.2 inversion provides a genetic basis for the joint susceptibility to asthma and obesity, with a population attributable risk of 39.7%. Differential mitochondrial function and basal energy balance of inversion alleles might also underlie the potential selection signature that led to their uneven distribution in world populations. Copyright © 2014 The American Society of Human Genetics. Published by Elsevier Inc. All rights reserved.

  18. A unified inversion scheme to process multifrequency measurements of various dispersive electromagnetic properties

    NASA Astrophysics Data System (ADS)

    Han, Y.; Misra, S.

    2018-04-01

    Multi-frequency measurement of a dispersive electromagnetic (EM) property, such as electrical conductivity, dielectric permittivity, or magnetic permeability, is commonly analyzed for purposes of material characterization. Such an analysis requires inversion of the multi-frequency measurement based on a specific relaxation model, such as Cole-Cole model or Pelton's model. We develop a unified inversion scheme that can be coupled to various type of relaxation models to independently process multi-frequency measurement of varied EM properties for purposes of improved EM-based geomaterial characterization. The proposed inversion scheme is firstly tested in few synthetic cases in which different relaxation models are coupled into the inversion scheme and then applied to multi-frequency complex conductivity, complex resistivity, complex permittivity, and complex impedance measurements. The method estimates up to seven relaxation-model parameters exhibiting convergence and accuracy for random initializations of the relaxation-model parameters within up to 3-orders of magnitude variation around the true parameter values. The proposed inversion method implements a bounded Levenberg algorithm with tuning initial values of damping parameter and its iterative adjustment factor, which are fixed in all the cases shown in this paper and irrespective of the type of measured EM property and the type of relaxation model. Notably, jump-out step and jump-back-in step are implemented as automated methods in the inversion scheme to prevent the inversion from getting trapped around local minima and to honor physical bounds of model parameters. The proposed inversion scheme can be easily used to process various types of EM measurements without major changes to the inversion scheme.

  19. The distribution and most recent common ancestor of the 17q21 inversion in humans.

    PubMed

    Donnelly, Michael P; Paschou, Peristera; Grigorenko, Elena; Gurwitz, David; Mehdi, Syed Qasim; Kajuna, Sylvester L B; Barta, Csaba; Kungulilo, Selemani; Karoma, N J; Lu, Ru-Band; Zhukova, Olga V; Kim, Jong-Jin; Comas, David; Siniscalco, Marcello; New, Maria; Li, Peining; Li, Hui; Manolopoulos, Vangelis G; Speed, William C; Rajeevan, Haseena; Pakstis, Andrew J; Kidd, Judith R; Kidd, Kenneth K

    2010-02-12

    The polymorphic inversion on 17q21, sometimes called the microtubular associated protein tau (MAPT) inversion, is an approximately 900 kb inversion found primarily in Europeans and Southwest Asians. We have identified 21 SNPs that act as markers of the inverted, i.e., H2, haplotype. The inversion is found at the highest frequencies in Southwest Asia and Southern Europe (frequencies of approximately 30%); elsewhere in Europe, frequencies vary from < 5%, in Finns, to 28%, in Orcadians. The H2 inversion haplotype also occurs at low frequencies in Africa, Central Asia, East Asia, and the Americas, though the East Asian and Amerindian alleles may be due to recent gene flow from Europe. Molecular evolution analyses indicate that the H2 haplotype originally arose in Africa or Southwest Asia. Though the H2 inversion has many fixed differences across the approximately 900 kb, short tandem repeat polymorphism data indicate a very recent date for the most recent common ancestor, with dates ranging from 13,600 to 108,400 years, depending on assumptions and estimation methods. This estimate range is much more recent than the 3 million year age estimated by Stefansson et al. in 2005. Copyright (c) 2010 The American Society of Human Genetics. Published by Elsevier Inc. All rights reserved.

  20. Research on fusion algorithm of polarization image in tetrolet domain

    NASA Astrophysics Data System (ADS)

    Zhang, Dexiang; Yuan, BaoHong; Zhang, Jingjing

    2015-12-01

    Tetrolets are Haar-type wavelets whose supports are tetrominoes which are shapes made by connecting four equal-sized squares. A fusion method for polarization images based on tetrolet transform is proposed. Firstly, the magnitude of polarization image and angle of polarization image can be decomposed into low-frequency coefficients and high-frequency coefficients with multi-scales and multi-directions using tetrolet transform. For the low-frequency coefficients, the average fusion method is used. According to edge distribution differences in high frequency sub-band images, for the directional high-frequency coefficients are used to select the better coefficients by region spectrum entropy algorithm for fusion. At last the fused image can be obtained by utilizing inverse transform for fused tetrolet coefficients. Experimental results show that the proposed method can detect image features more effectively and the fused image has better subjective visual effect

  1. Use of time series and harmonic constituents of tidal propagation to enhance estimation of coastal aquifer heterogeneity

    USGS Publications Warehouse

    Hughes, Joseph D.; White, Jeremy T.; Langevin, Christian D.

    2010-01-01

    A synthetic two‐dimensional model of a horizontally and vertically heterogeneous confined coastal aquifer system, based on the Upper Floridan aquifer in south Florida, USA, subjected to constant recharge and a complex tidal signal was used to generate 15‐minute water‐level data at select locations over a 7‐day simulation period.   “Observed” water‐level data were generated by adding noise, representative of typical barometric pressure variations and measurement errors, to 15‐minute data from the synthetic model. Permeability was calibrated using a non‐linear gradient‐based parameter inversion approach with preferred‐value Tikhonov regularization and 1) “observed” water‐level data, 2) harmonic constituent data, or 3) a combination of “observed” water‐level and harmonic constituent data.    In all cases, high‐frequency data used in the parameter inversion process were able to characterize broad‐scale heterogeneities; the ability to discern fine‐scale heterogeneity was greater when harmonic constituent data were used.  These results suggest that the combined use of highly parameterized‐inversion techniques and high frequency time and/or processed‐harmonic constituent water‐level data could be a useful approach to better characterize aquifer heterogeneities in coastal aquifers influenced by ocean tides.

  2. Molecular Variation of Adh and P6 Genes in an African Population of Drosophila Melanogaster and Its Relation to Chromosomal Inversions

    PubMed Central

    Benassi, V.; Aulard, S.; Mazeau, S.; Veuille, M.

    1993-01-01

    Four-cutter molecular polymorphism of Adh and P6, and chromosome inversion polymorphism of chromosome II were investigated in 95 isogenic lines of an Ivory Coast population of Drosophila melanogaster, a species assumed to have recently spread throughout the world from a West African origin. The P6 gene showed little linkage disequilibrium with the In(2L)t inversion, although it is located within this inversion. This suggests that the inversion and the P6 locus have extensively exchanged genetic information through either double crossover or gene conversion. Allozymic variation in ADH was in linkage disequilibrium with In(2L)t and In(2R)NS inversions. Evidence suggests either that inversion linkage with the Fast allele is selectively maintained, or that this allele only recently appeared. Molecular polymorphism at the Adh locus in the Ivory Coast is not higher than in North American populations. New haplotypes specific to the African population were found, some of them connect the ``Wa(s)-like'' haplotypes found at high frequencies in the United States to the other slow haplotypes. Their relation with In(2L)t supports the hypothesis that Wa(s) recently recombined away from an In(2L)t chromosome which may be the cause of its divergence from the other haplotypes. PMID:8349110

  3. Satisfaction (sexual, life, relationship, and mental health) is associated directly with penile-vaginal intercourse, but inversely with other sexual behavior frequencies.

    PubMed

    Brody, Stuart; Costa, Rui Miguel

    2009-07-01

    Some sex therapists and educators assume that many sexual behaviors provide comparable sexual satisfaction. Evidence is required to determine whether sexual behaviors differ in their associations with both sexual satisfaction and satisfaction with other aspects of life. To test the hypothesis that satisfaction with sex life, life in general, sexual partnership, and mental health correlates directly with frequency of penile-vaginal intercourse (PVI) and inversely with frequency of both masturbation and partnered sexual activity excluding PVI (noncoital sex). A representative sample of 2,810 Swedes reported frequency of PVI, noncoital sex, and masturbation during the past 30 days, and degree of satisfaction with their sex life, life in general, partnership, and mental health. Multivariate analyses (for the sexes separately and combined) considering the different satisfaction parameters as dependent variables, and the different types of sexual activities (and age) as putative predictors. For both sexes, multivariate analyses revealed that PVI frequency was directly associated with all satisfaction measures (part correlation = 0.50 with sexual satisfaction), masturbation frequency was independently inversely associated with almost all satisfaction measures, and noncoital sex frequencies independently inversely associated with some satisfaction measures (and uncorrelated with the rest). Age did not confound the results. The results are consistent with evidence that specifically PVI frequency, rather than other sexual activities, is associated with sexual satisfaction, health, and well-being. Inverse associations between satisfaction and masturbation are not due simply to insufficient PVI.

  4. Empirical Distributions of F ST from Large-Scale Human Polymorphism Data

    PubMed Central

    Elhaik, Eran

    2012-01-01

    Studies of the apportionment of human genetic variation have long established that most human variation is within population groups and that the additional variation between population groups is small but greatest when comparing different continental populations. These studies often used Wright’s F ST that apportions the standardized variance in allele frequencies within and between population groups. Because local adaptations increase population differentiation, high-F ST may be found at closely linked loci under selection and used to identify genes undergoing directional or heterotic selection. We re-examined these processes using HapMap data. We analyzed 3 million SNPs on 602 samples from eight worldwide populations and a consensus subset of 1 million SNPs found in all populations. We identified four major features of the data: First, a hierarchically F ST analysis showed that only a paucity (12%) of the total genetic variation is distributed between continental populations and even a lesser genetic variation (1%) is found between intra-continental populations. Second, the global F ST distribution closely follows an exponential distribution. Third, although the overall F ST distribution is similarly shaped (inverse J), F ST distributions varies markedly by allele frequency when divided into non-overlapping groups by allele frequency range. Because the mean allele frequency is a crude indicator of allele age, these distributions mark the time-dependent change in genetic differentiation. Finally, the change in mean-F ST of these groups is linear in allele frequency. These results suggest that investigating the extremes of the F ST distribution for each allele frequency group is more efficient for detecting selection. Consequently, we demonstrate that such extreme SNPs are more clustered along the chromosomes than expected from linkage disequilibrium for each allele frequency group. These genomic regions are therefore likely candidates for natural selection. PMID:23185452

  5. Empirical distributions of F(ST) from large-scale human polymorphism data.

    PubMed

    Elhaik, Eran

    2012-01-01

    Studies of the apportionment of human genetic variation have long established that most human variation is within population groups and that the additional variation between population groups is small but greatest when comparing different continental populations. These studies often used Wright's F(ST) that apportions the standardized variance in allele frequencies within and between population groups. Because local adaptations increase population differentiation, high-F(ST) may be found at closely linked loci under selection and used to identify genes undergoing directional or heterotic selection. We re-examined these processes using HapMap data. We analyzed 3 million SNPs on 602 samples from eight worldwide populations and a consensus subset of 1 million SNPs found in all populations. We identified four major features of the data: First, a hierarchically F(ST) analysis showed that only a paucity (12%) of the total genetic variation is distributed between continental populations and even a lesser genetic variation (1%) is found between intra-continental populations. Second, the global F(ST) distribution closely follows an exponential distribution. Third, although the overall F(ST) distribution is similarly shaped (inverse J), F(ST) distributions varies markedly by allele frequency when divided into non-overlapping groups by allele frequency range. Because the mean allele frequency is a crude indicator of allele age, these distributions mark the time-dependent change in genetic differentiation. Finally, the change in mean-F(ST) of these groups is linear in allele frequency. These results suggest that investigating the extremes of the F(ST) distribution for each allele frequency group is more efficient for detecting selection. Consequently, we demonstrate that such extreme SNPs are more clustered along the chromosomes than expected from linkage disequilibrium for each allele frequency group. These genomic regions are therefore likely candidates for natural selection.

  6. Frequency swept microwaves for hyperfine decoupling and time domain dynamic nuclear polarization

    PubMed Central

    Hoff, Daniel E.M.; Albert, Brice J.; Saliba, Edward P.; Scott, Faith J.; Choi, Eric J.; Mardini, Michael; Barnes, Alexander B.

    2015-01-01

    Hyperfine decoupling and pulsed dynamic nuclear polarization (DNP) are promising techniques to improve high field DNP NMR. We explore experimental and theoretical considerations to implement them with magic angle spinning (MAS). Microwave field simulations using the high frequency structural simulator (HFSS) software suite are performed to characterize the inhomogeneous phase independent microwave field throughout a 198 GHz MAS DNP probe. Our calculations show that a microwave power input of 17 W is required to generate an average EPR nutation frequency of 0.84 MHz. We also present a detailed calculation of microwave heating from the HFSS parameters and find that 7.1% of the incident microwave power contributes to dielectric sample heating. Voltage tunable gyrotron oscillators are proposed as a class of frequency agile microwave sources to generate microwave frequency sweeps required for the frequency modulated cross effect, electron spin inversions, and hyperfine decoupling. Electron spin inversions of stable organic radicals are simulated with SPINEVOLUTION using the inhomogeneous microwave fields calculated by HFSS. We calculate an electron spin inversion efficiency of 56% at a spinning frequency of 5 kHz. Finally, we demonstrate gyrotron acceleration potentials required to generate swept microwave frequency profiles for the frequency modulated cross effect and electron spin inversions. PMID:26482131

  7. Frequency swept microwaves for hyperfine decoupling and time domain dynamic nuclear polarization.

    PubMed

    Hoff, Daniel E M; Albert, Brice J; Saliba, Edward P; Scott, Faith J; Choi, Eric J; Mardini, Michael; Barnes, Alexander B

    2015-11-01

    Hyperfine decoupling and pulsed dynamic nuclear polarization (DNP) are promising techniques to improve high field DNP NMR. We explore experimental and theoretical considerations to implement them with magic angle spinning (MAS). Microwave field simulations using the high frequency structural simulator (HFSS) software suite are performed to characterize the inhomogeneous phase independent microwave field throughout a 198GHz MAS DNP probe. Our calculations show that a microwave power input of 17W is required to generate an average EPR nutation frequency of 0.84MHz. We also present a detailed calculation of microwave heating from the HFSS parameters and find that 7.1% of the incident microwave power contributes to dielectric sample heating. Voltage tunable gyrotron oscillators are proposed as a class of frequency agile microwave sources to generate microwave frequency sweeps required for the frequency modulated cross effect, electron spin inversions, and hyperfine decoupling. Electron spin inversions of stable organic radicals are simulated with SPINEVOLUTION using the inhomogeneous microwave fields calculated by HFSS. We calculate an electron spin inversion efficiency of 56% at a spinning frequency of 5kHz. Finally, we demonstrate gyrotron acceleration potentials required to generate swept microwave frequency profiles for the frequency modulated cross effect and electron spin inversions. Copyright © 2015 Elsevier Inc. All rights reserved.

  8. Calculation of the transitions in the amine inversion vibration of some local anesthetics

    NASA Astrophysics Data System (ADS)

    Alcolea Palafox, M.

    1988-05-01

    In the para-amino group of the local anesthetics benzocaine, procaine and procaine hydrochloride, the potential function of inversion, the barrier height V̂ i and the optimum ω o inversion angle have been determinated. Two methods are shown for calculating transitions based on the two frequencies of inversion which easily can be detected in the infrared absorption and Raman spectra in solid compounds. Also the frequencies associated with tra nsitions are able to be obtained.

  9. Adiabatic and fast passage ultra-wideband inversion in pulsed EPR.

    PubMed

    Doll, Andrin; Pribitzer, Stephan; Tschaggelar, René; Jeschke, Gunnar

    2013-05-01

    We demonstrate that adiabatic and fast passage ultra-wideband (UWB) pulses can achieve inversion over several hundreds of MHz and thus enhance the measurement sensitivity, as shown by two selected experiments. Technically, frequency-swept pulses are generated by a 12 GS/s arbitrary waveform generator and upconverted to X-band frequencies. This pulsed UWB source is utilized as an incoherent channel in an ordinary pulsed EPR spectrometer. We discuss experimental methodologies and modeling techniques to account for the response of the resonator, which can strongly limit the excitation bandwidth of the entire non-linear excitation chain. Aided by these procedures, pulses compensated for bandwidth or variations in group delay reveal enhanced inversion efficiency. The degree of bandwidth compensation is shown to depend critically on the time available for excitation. As a result, we demonstrate optimized inversion recovery and double electron electron resonance (DEER) experiments. First, virtually complete inversion of the nitroxide spectrum with an adiabatic pulse of 128ns length is achieved. Consequently, spectral diffusion between inverted and non-inverted spins is largely suppressed and the observation bandwidth can be increased to increase measurement sensitivity. Second, DEER is performed on a terpyridine-based copper (II) complex with a nitroxide-copper distance of 2.5nm. As previously demonstrated on this complex, when pumping copper spins and observing nitroxide spins, the modulation depth is severely limited by the excitation bandwidth of the pump pulse. By using fast passage UWB pulses with a maximum length of 64ns, we achieve up to threefold enhancement of the modulation depth. Associated artifacts in distance distributions when increasing the bandwidth of the pump pulse are shown to be small. Copyright © 2013 Elsevier Inc. All rights reserved.

  10. A comprehensive inversion approach for feedforward compensation of piezoactuator system at high frequency

    NASA Astrophysics Data System (ADS)

    Tian, Lizhi; Xiong, Zhenhua; Wu, Jianhua; Ding, Han

    2016-09-01

    Motion control of the piezoactuator system over broadband frequencies is limited due to its inherent hysteresis and system dynamics. One of the suggested ways is to use feedforward controller to linearize the input-output relationship of the piezoactuator system. Although there have been many feedforward approaches, it is still a challenge to develop feedforward controller for the piezoactuator system at high frequency. Hence, this paper presents a comprehensive inversion approach in consideration of the coupling of hysteresis and dynamics. In this work, the influence of dynamics compensation on the input-output relationship of the piezoactuator system is investigated first. With system dynamics compensation, the input-output relationship of the piezoactuator system will be further represented as rate-dependent nonlinearity due to the inevitable dynamics compensation error, especially at high frequency. Base on this result, the feedforward controller composed by a cascade of linear dynamics inversion and rate-dependent nonlinearity inversion is developed. Then, the system identification of the comprehensive inversion approach is proposed. Finally, experimental results show that the proposed approach can improve the performance on tracking of both periodic and non-periodic trajectories at medium and high frequency compared with the conventional feedforward approaches.

  11. A Comparison of Solar p-Mode Parameters from MDI and Gong: Mode Frequencies and Structure Inversions

    NASA Technical Reports Server (NTRS)

    Basu, S.; Christensen-Dalsgaard, J.; Howe, R.; Schou, J.; Thompson, M. J.; Hill, F.; Komm, R.

    2003-01-01

    Helioseismic analysis of solar global oscillations allows investigation of the internal structure of the Sun. One important test of the reliability of the inferences from helioseismology is that the results from independent sets of contemporaneous data are consistent with one another. Here we compare mode frequencies from the Global Oscillation Network Group and Michelson Doppler Imager on board SOHO and resulting inversion results on the Sun's internal structure. The average relative differences between the data sets are typically less than 1 x 10(exp -5) substantially smaller than the formal errors in the differences; however, in some cases the frequency differences show a systematic behavior that might nonetheless influence the inversion results. We find that the differences in frequencies are not a result of instrumental effects but are almost entirely related to the data pipeline software. Inversion of the frequencies shows that their differences do not result in any significant effects on the resulting inferences on solar structure. We have also experimented with fitting asymmetric profiles to the oscillation power spectra and find that, compared with the symmetric fits, this causes no significant change in the inversion results.

  12. A multi-frequency receiver function inversion approach for crustal velocity structure

    NASA Astrophysics Data System (ADS)

    Li, Xuelei; Li, Zhiwei; Hao, Tianyao; Wang, Sheng; Xing, Jian

    2017-05-01

    In order to constrain the crustal velocity structures better, we developed a new nonlinear inversion approach based on multi-frequency receiver function waveforms. With the global optimizing algorithm of Differential Evolution (DE), low-frequency receiver function waveforms can primarily constrain large-scale velocity structures, while high-frequency receiver function waveforms show the advantages in recovering small-scale velocity structures. Based on the synthetic tests with multi-frequency receiver function waveforms, the proposed approach can constrain both long- and short-wavelength characteristics of the crustal velocity structures simultaneously. Inversions with real data are also conducted for the seismic stations of KMNB in southeast China and HYB in Indian continent, where crustal structures have been well studied by former researchers. Comparisons of inverted velocity models from previous and our studies suggest good consistency, but better waveform fitness with fewer model parameters are achieved by our proposed approach. Comprehensive tests with synthetic and real data suggest that the proposed inversion approach with multi-frequency receiver function is effective and robust in inverting the crustal velocity structures.

  13. Moment tensor inversion with three-dimensional sensor configuration of mining induced seismicity (Kiruna mine, Sweden)

    NASA Astrophysics Data System (ADS)

    Ma, Ju; Dineva, Savka; Cesca, Simone; Heimann, Sebastian

    2018-06-01

    Mining induced seismicity is an undesired consequence of mining operations, which poses significant hazard to miners and infrastructures and requires an accurate analysis of the rupture process. Seismic moment tensors of mining-induced events help to understand the nature of mining-induced seismicity by providing information about the relationship between the mining, stress redistribution and instabilities in the rock mass. In this work, we adapt and test a waveform-based inversion method on high frequency data recorded by a dense underground seismic system in one of the largest underground mines in the world (Kiruna mine, Sweden). A stable algorithm for moment tensor inversion for comparatively small mining induced earthquakes, resolving both the double-couple and full moment tensor with high frequency data, is very challenging. Moreover, the application to underground mining system requires accounting for the 3-D geometry of the monitoring system. We construct a Green's function database using a homogeneous velocity model, but assuming a 3-D distribution of potential sources and receivers. We first perform a set of moment tensor inversions using synthetic data to test the effects of different factors on moment tensor inversion stability and source parameters accuracy, including the network spatial coverage, the number of sensors and the signal-to-noise ratio. The influence of the accuracy of the input source parameters on the inversion results is also tested. Those tests show that an accurate selection of the inversion parameters allows resolving the moment tensor also in the presence of realistic seismic noise conditions. Finally, the moment tensor inversion methodology is applied to eight events chosen from mining block #33/34 at Kiruna mine. Source parameters including scalar moment, magnitude, double-couple, compensated linear vector dipole and isotropic contributions as well as the strike, dip and rake configurations of the double-couple term were obtained. The orientations of the nodal planes of the double-couple component in most cases vary from NNW to NNE with a dip along the ore body or in the opposite direction.

  14. Moment Tensor Inversion with 3D sensor configuration of Mining Induced Seismicity (Kiruna mine, Sweden)

    NASA Astrophysics Data System (ADS)

    Ma, Ju; Dineva, Savka; Cesca, Simone; Heimann, Sebastian

    2018-03-01

    Mining induced seismicity is an undesired consequence of mining operations, which poses significant hazard to miners and infrastructures and requires an accurate analysis of the rupture process. Seismic moment tensors of mining-induced events help to understand the nature of mining-induced seismicity by providing information about the relationship between the mining, stress redistribution and instabilities in the rock mass. In this work, we adapt and test a waveform-based inversion method on high frequency data recorded by a dense underground seismic system in one of the largest underground mines in the world (Kiruna mine, Sweden). Stable algorithm for moment tensor inversion for comparatively small mining induced earthquakes, resolving both the double couple and full moment tensor with high frequency data is very challenging. Moreover, the application to underground mining system requires accounting for the 3D geometry of the monitoring system. We construct a Green's function database using a homogeneous velocity model, but assuming a 3D distribution of potential sources and receivers. We first perform a set of moment tensor inversions using synthetic data to test the effects of different factors on moment tensor inversion stability and source parameters accuracy, including the network spatial coverage, the number of sensors and the signal-to-noise ratio. The influence of the accuracy of the input source parameters on the inversion results is also tested. Those tests show that an accurate selection of the inversion parameters allows resolving the moment tensor also in presence of realistic seismic noise conditions. Finally, the moment tensor inversion methodology is applied to 8 events chosen from mining block #33/34 at Kiruna mine. Source parameters including scalar moment, magnitude, double couple, compensated linear vector dipole and isotropic contributions as well as the strike, dip, rake configurations of the double couple term were obtained. The orientations of the nodal planes of the double-couple component in most cases vary from NNW to NNE with a dip along the ore body or in the opposite direction.

  15. Unity power factor converter

    NASA Technical Reports Server (NTRS)

    Wester, Gene W. (Inventor)

    1980-01-01

    A unity power factor converter capable of effecting either inversion (dc-to-dc) or rectification (ac-to-dc), and capable of providing bilateral power control from a DC source (or load) through an AC transmission line to a DC load (or source) for power flow in either direction, is comprised of comparators for comparing the AC current i with an AC signal i.sub.ref (or its phase inversion) derived from the AC ports to generate control signals to operate a switch control circuit for high speed switching to shape the AC current waveform to a sine waveform, and synchronize it in phase and frequency with the AC voltage at the AC ports, by selectively switching the connections to a series inductor as required to increase or decrease the current i.

  16. Method and apparatus for wavefront sensing

    DOEpatents

    Bahk, Seung-Whan

    2016-08-23

    A method of measuring characteristics of a wavefront of an incident beam includes obtaining an interferogram associated with the incident beam passing through a transmission mask and Fourier transforming the interferogram to provide a frequency domain interferogram. The method also includes selecting a subset of harmonics from the frequency domain interferogram, individually inverse Fourier transforming each of the subset of harmonics to provide a set of spatial domain harmonics, and extracting a phase profile from each of the set of spatial domain harmonics. The method further includes removing phase discontinuities in the phase profile, rotating the phase profile, and reconstructing a phase front of the wavefront of the incident beam.

  17. Stochastic Gabor reflectivity and acoustic impedance inversion

    NASA Astrophysics Data System (ADS)

    Hariri Naghadeh, Diako; Morley, Christopher Keith; Ferguson, Angus John

    2018-02-01

    To delineate subsurface lithology to estimate petrophysical properties of a reservoir, it is possible to use acoustic impedance (AI) which is the result of seismic inversion. To change amplitude to AI, removal of wavelet effects from the seismic signal in order to get a reflection series, and subsequently transforming those reflections to AI, is vital. To carry out seismic inversion correctly it is important to not assume that the seismic signal is stationary. However, all stationary deconvolution methods are designed following that assumption. To increase temporal resolution and interpretation ability, amplitude compensation and phase correction are inevitable. Those are pitfalls of stationary reflectivity inversion. Although stationary reflectivity inversion methods are trying to estimate reflectivity series, because of incorrect assumptions their estimations will not be correct, but may be useful. Trying to convert those reflection series to AI, also merging with the low frequency initial model, can help us. The aim of this study was to apply non-stationary deconvolution to eliminate time variant wavelet effects from the signal and to convert the estimated reflection series to the absolute AI by getting bias from well logs. To carry out this aim, stochastic Gabor inversion in the time domain was used. The Gabor transform derived the signal’s time-frequency analysis and estimated wavelet properties from different windows. Dealing with different time windows gave an ability to create a time-variant kernel matrix, which was used to remove matrix effects from seismic data. The result was a reflection series that does not follow the stationary assumption. The subsequent step was to convert those reflections to AI using well information. Synthetic and real data sets were used to show the ability of the introduced method. The results highlight that the time cost to get seismic inversion is negligible related to general Gabor inversion in the frequency domain. Also, obtaining bias could help the method to estimate reliable AI. To justify the effect of random noise on deterministic and stochastic inversion results, a stationary noisy trace with signal-to-noise ratio equal to 2 was used. The results highlight the inability of deterministic inversion in dealing with a noisy data set even using a high number of regularization parameters. Also, despite the low level of signal, stochastic Gabor inversion not only can estimate correctly the wavelet’s properties but also, because of bias from well logs, the inversion result is very close to the real AI. Comparing deterministic and introduced inversion results on a real data set shows that low resolution results, especially in the deeper parts of seismic sections using deterministic inversion, creates significant reliability problems for seismic prospects, but this pitfall is solved completely using stochastic Gabor inversion. The estimated AI using Gabor inversion in the time domain is much better and faster than general Gabor inversion in the frequency domain. This is due to the extra number of windows required to analyze the time-frequency information and also the amount of temporal increment between windows. In contrast, stochastic Gabor inversion can estimate trustable physical properties close to the real characteristics. Applying to a real data set could give an ability to detect the direction of volcanic intrusion and the ability of lithology distribution delineation along the fan. Comparing the inversion results highlights the efficiency of stochastic Gabor inversion to delineate lateral lithology changes because of the improved frequency content and zero phasing of the final inversion volume.

  18. An Oscillation of the Crack-like Conduit at Nevado del Ruiz Volcano, Colombia, Inferred from Multi-band Analyses of Very Long Period Seismic Events

    NASA Astrophysics Data System (ADS)

    Maeda, Y.; Kumagai, H.; Londono, J. M.; Lopez, C. M.; Castaño, L. M.; Beatriz, B.; García, L.

    2017-12-01

    Nevado del Ruiz is an active volcano in Colombia, which continues eruption activity and has been monitored by 13 broadband and 3 short-period seismic stations. In 2015-2016, a joint Japan-Colombia team installed an automatic event detection and location system based on the amplitude source location (ASL) method. Kumagai et al. (IAVCEI, 2017) indicated the existence of a magma conduit extending from the NW flank to the summit based on ASL analyses of various seismic signals including long-period (LP) and very long period (VLP) events and tremors in a 5-10 Hz frequency band. In this study, we analyzed the VLP events by waveform inversion using eight summit stations in a frequency band of 0.3-0.7 Hz. We selected 14 VLP events from May to December 2016 based on signal-to-noise ratios and simplicity of the waveforms. We assumed a homogeneous P-wave velocity of 3.5 km/s with topography in the calculation of the Green functions. We conducted frequency-domain waveform inversion assuming a tensile crack source and investigated the best location and orientation of the crack by a grid search. The inversion results pointed to a low-angle ( 30°) NW-dipping crack near the top of the conduit (approximately 1 km below the summit). The estimated source time functions displayed two or three cycles of oscillations with the seismic moment of order of 1010-1011 N m. For these 14 events, the ASLs from the 5-10 Hz frequency band were also near the top of the conduit. These results suggest the VLP and high-frequency signals are generated by an oscillation of the crack-like conduit near the summit, which may be triggered by a volume change of magma ascending in the conduit.

  19. Resolution enhancement of robust Bayesian pre-stack inversion in the frequency domain

    NASA Astrophysics Data System (ADS)

    Yin, Xingyao; Li, Kun; Zong, Zhaoyun

    2016-10-01

    AVO/AVA (amplitude variation with an offset or angle) inversion is one of the most practical and useful approaches to estimating model parameters. So far, publications on AVO inversion in the Fourier domain have been quite limited in view of its poor stability and sensitivity to noise compared with time-domain inversion. For the resolution and stability of AVO inversion in the Fourier domain, a novel robust Bayesian pre-stack AVO inversion based on the mixed domain formulation of stationary convolution is proposed which could solve the instability and achieve superior resolution. The Fourier operator will be integrated into the objective equation and it avoids the Fourier inverse transform in our inversion process. Furthermore, the background constraints of model parameters are taken into consideration to improve the stability and reliability of inversion which could compensate for the low-frequency components of seismic signals. Besides, the different frequency components of seismic signals can realize decoupling automatically. This will help us to solve the inverse problem by means of multi-component successive iterations and the convergence precision of the inverse problem could be improved. So, superior resolution compared with the conventional time-domain pre-stack inversion could be achieved easily. Synthetic tests illustrate that the proposed method could achieve high-resolution results with a high degree of agreement with the theoretical model and verify the quality of anti-noise. Finally, applications on a field data case demonstrate that the proposed method could obtain stable inversion results of elastic parameters from pre-stack seismic data in conformity with the real logging data.

  20. An Effective Method for Inversion of Elastic Impedance for Shallow Sediments and Its Application to Gas Hydrate-Bearing Sediments

    USGS Publications Warehouse

    Lee, Myung W.

    2006-01-01

    Elastic properties of gas hydrate-bearing sediments (GHBS) are important for identifying and quantifying gas hydrate as well as discriminating the effects of free gas on velocity from that due to overpressure. Elastic properties of GHBS sediments can be estimated from elastic inversion using the elastic impedance. The accuracy of elastic inversion can be increased by using the predicted S-wave velocity (Vs) in the parameter k, which is k = (Vs / Vp)2. However, when Vs is less than about 0.6 kilometer per second, the inversion is inaccurate, partly because of the difficulty in accurately predicting low S-wave velocities and partly because of the large error associated with small k values. A new formula that leads to estimates of only the high-frequency part of velocity is proposed by decomposing Vs into low- and high-frequency parts. This new inversion formula is applied to a variety of well logs, and the results demonstrate its effectiveness for all ranges of Vs as long as the deviation of Vs from the low-frequency part of Vs is small. For GHBS, the deviation of Vs from the low-frequency part of Vs can be large for moderate to high gas hydrate saturations. Therefore, the new formula is not effective for elastic inversion for GHBS unless the gas hydrate effect is incorporated into the low-frequency part of Vs. For inversion of GHBS with Vs greater than about 0.6 kilometer per second, the original formulation is preferable.

  1. Joint inversion of high-frequency surface waves with fundamental and higher modes

    USGS Publications Warehouse

    Luo, Y.; Xia, J.; Liu, J.; Liu, Q.; Xu, S.

    2007-01-01

    Joint inversion of multimode surface waves for estimating the shear (S)-wave velocity has received much attention in recent years. In this paper, we first analyze sensitivity of phase velocities of multimodes of surface waves for a six-layer earth model, and then we invert surface-wave dispersion curves of the theoretical model and a real-world example. Sensitivity analysis shows that fundamental mode data are more sensitive to the S-wave velocities of shallow layers and are concentrated on a very narrow frequency band, while higher mode data are more sensitive to the parameters of relatively deeper layers and are distributed over a wider frequency band. These properties provide a foundation of using a multimode joint inversion to define S-wave velocities. Inversion results of both synthetic data and a real-world example demonstrate that joint inversion with the damped least-square method and the singular-value decomposition technique to invert high-frequency surface waves with fundamental and higher mode data simultaneously can effectively reduce the ambiguity and improve the accuracy of S-wave velocities. ?? 2007.

  2. Frequency Selection for Multi-frequency Acoustic Measurement of Suspended Sediment

    NASA Astrophysics Data System (ADS)

    Chen, X.; HO, H.; Fu, X.

    2017-12-01

    Multi-frequency acoustic measurement of suspended sediment has found successful applications in marine and fluvial environments. Difficult challenges remain in regard to improving its effectiveness and efficiency when applied to high concentrations and wide size distributions in rivers. We performed a multi-frequency acoustic scattering experiment in a cylindrical tank with a suspension of natural sands. The sands range from 50 to 600 μm in diameter with a lognormal size distribution. The bulk concentration of suspended sediment varied from 1.0 to 12.0 g/L. We found that the commonly used linear relationship between the intensity of acoustic backscatter and suspended sediment concentration holds only at sufficiently low concentrations, for instance below 3.0 g/L. It fails at a critical value of concentration that depends on measurement frequency and the distance between the transducer and the target point. Instead, an exponential relationship was found to work satisfactorily throughout the entire range of concentration. The coefficient and exponent of the exponential function changed, however, with the measuring frequency and distance. Considering the increased complexity of inverting the concentration values when an exponential relationship prevails, we further analyzed the relationship between measurement error and measuring frequency. It was also found that the inversion error may be effectively controlled within 5% if the frequency is properly set. Compared with concentration, grain size was found to heavily affect the selection of optimum frequency. A regression relationship for optimum frequency versus grain size was developed based on the experimental results.

  3. Inverse European Latitudinal Cline at the timeless Locus of Drosophila melanogaster Reveals Selection on a Clock Gene: Population Genetics of ls-tim.

    PubMed

    Zonato, Valeria; Vanin, Stefano; Costa, Rodolfo; Tauber, Eran; Kyriacou, Charalambos P

    2018-02-01

    The spread of adaptive genetic variants in populations is a cornerstone of evolutionary theory but with relatively few biologically well-understood examples. Previous work on the ls-tim variant of timeless, which encodes the light-sensitive circadian regulator in Drosophila melanogaster, suggests that it may have originated in southeastern Italy. Flies characterized by the new allele show photoperiod-related phenotypes likely to be adaptive in seasonal environments. ls-tim may be spreading from its point of origin in Italy by directional selection, but there are alternative explanations for its observed clinal geographical distribution, including balancing selection and demography. From population analyses of ls-tim frequencies collected on the eastern side of the Iberian Peninsula, we show that ls-tim frequencies are inverted compared with those in Italy. This pattern is consistent with a scenario of directional selection rather than latitude-associated balancing selection. Neutrality tests further reveal the signature of directional selection at the ls-tim site, which is reduced a few kb pairs either side of ls-tim. A reanalysis of allele frequencies from a large number of microsatellite loci do not demonstrate any frequent ls-tim-like spatial patterns, so a general demographic effect or population expansion from southeastern Italy cannot readily explain current ls-tim frequencies. Finally, a revised estimate of the age of ls-tim allele using linkage disequilibrium and coalescent-based approaches reveals that it may be only 300 to 3000 years old, perhaps explaining why it has not yet gone to fixation. ls-tim thus provides a rare temporal snapshot of a new allele that has come under selection before it reaches equilibrium.

  4. Direct Iterative Nonlinear Inversion by Multi-frequency T-matrix Completion

    NASA Astrophysics Data System (ADS)

    Jakobsen, M.; Wu, R. S.

    2016-12-01

    Researchers in the mathematical physics community have recently proposed a conceptually new method for solving nonlinear inverse scattering problems (like FWI) which is inspired by the theory of nonlocality of physical interactions. The conceptually new method, which may be referred to as the T-matrix completion method, is very interesting since it is not based on linearization at any stage. Also, there are no gradient vectors or (inverse) Hessian matrices to calculate. However, the convergence radius of this promising T-matrix completion method is seriously restricted by it's use of single-frequency scattering data only. In this study, we have developed a modified version of the T-matrix completion method which we believe is more suitable for applications to nonlinear inverse scattering problems in (exploration) seismology, because it makes use of multi-frequency data. Essentially, we have simplified the single-frequency T-matrix completion method of Levinson and Markel and combined it with the standard sequential frequency inversion (multi-scale regularization) method. For each frequency, we first estimate the experimental T-matrix by using the Moore-Penrose pseudo inverse concept. Then this experimental T-matrix is used to initiate an iterative procedure for successive estimation of the scattering potential and the T-matrix using the Lippmann-Schwinger for the nonlinear relation between these two quantities. The main physical requirements in the basic iterative cycle is that the T-matrix should be data-compatible and the scattering potential operator should be dominantly local; although a non-local scattering potential operator is allowed in the intermediate iterations. In our simplified T-matrix completion strategy, we ensure that the T-matrix updates are always data compatible simply by adding a suitable correction term in the real space coordinate representation. The use of singular-value decomposition representations are not required in our formulation since we have developed an efficient domain decomposition method. The results of several numerical experiments for the SEG/EAGE salt model illustrate the importance of using multi-frequency data when performing frequency domain full waveform inversion in strongly scattering media via the new concept of T-matrix completion.

  5. Spectral filtering of gradient for l2-norm frequency-domain elastic waveform inversion

    NASA Astrophysics Data System (ADS)

    Oh, Ju-Won; Min, Dong-Joo

    2013-05-01

    To enhance the robustness of the l2-norm elastic full-waveform inversion (FWI), we propose a denoise function that is incorporated into single-frequency gradients. Because field data are noisy and modelled data are noise-free, the denoise function is designed based on the ratio of modelled data to field data summed over shots and receivers. We first take the sums of the modelled data and field data over shots, then take the sums of the absolute values of the resultant modelled data and field data over the receivers. Due to the monochromatic property of wavefields at each frequency, signals in both modelled and field data tend to be cancelled out or maintained, whereas certain types of noise, particularly random noise, can be amplified in field data. As a result, the spectral distribution of the denoise function is inversely proportional to the ratio of noise to signal at each frequency, which helps prevent the noise-dominant gradients from contributing to model parameter updates. Numerical examples show that the spectral distribution of the denoise function resembles a frequency filter that is determined by the spectrum of the signal-to-noise (S/N) ratio during the inversion process, with little human intervention. The denoise function is applied to the elastic FWI of synthetic data, with three types of random noise generated by the modified version of the Marmousi-2 model: white, low-frequency and high-frequency random noises. Based on the spectrum of S/N ratios at each frequency, the denoise function mainly suppresses noise-dominant single-frequency gradients, which improves the inversion results at the cost of spatial resolution.

  6. Research on the range side lobe suppression method for modulated stepped frequency radar signals

    NASA Astrophysics Data System (ADS)

    Liu, Yinkai; Shan, Tao; Feng, Yuan

    2018-05-01

    The magnitude of time-domain range sidelobe of modulated stepped frequency radar affects the imaging quality of inverse synthetic aperture radar (ISAR). In this paper, the cause of high sidelobe in modulated stepped frequency radar imaging is analyzed first in real environment. Then, the chaos particle swarm optimization (CPSO) is used to select the amplitude and phase compensation factors according to the minimum sidelobe criterion. Finally, the compensated one-dimensional range images are obtained. Experimental results show that the amplitude-phase compensation method based on CPSO algorithm can effectively reduce the sidelobe peak value of one-dimensional range images, which outperforms the common sidelobe suppression methods and avoids the coverage of weak scattering points by strong scattering points due to the high sidelobes.

  7. Improving resolution of crosswell seismic section based on time-frequency analysis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Luo, H.; Li, Y.

    1994-12-31

    According to signal theory, to improve resolution of seismic section is to extend high-frequency band of seismic signal. In cross-well section, sonic log can be regarded as a reliable source providing high-frequency information to the trace near the borehole. In such case, what to do is to introduce this high-frequency information into the whole section. However, neither traditional deconvolution algorithms nor some new inversion methods such as BCI (Broad Constraint Inversion) are satisfied because of high-frequency noise and nonuniqueness of inversion results respectively. To overcome their disadvantages, this paper presents a new algorithm based on Time-Frequency Analysis (TFA) technology whichmore » has been increasingly received much attention as an useful signal analysis too. Practical applications show that the new method is a stable scheme to improve resolution of cross-well seismic section greatly without decreasing Signal to Noise Ratio (SNR).« less

  8. High Accuracy Optical Inverse Square Law Experiment Using Inexpensive Light to Frequency Converters

    ERIC Educational Resources Information Center

    Wanser, Keith H.; Mahrley, Steve; Tanner, Joshua

    2012-01-01

    In this paper we report on the use of two different light to frequency converters, four different light sources, three of which are novel and inexpensive, and a hand held digital multimeter with a frequency counter, suitable for making accurate and rapid determination of the optical inverse square law exponent of -2 to better than [plus or…

  9. Ferroelectric domain inversion and its stability in lithium niobate thin film on insulator with different thicknesses

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shao, Guang-hao; Bai, Yu-hang; Cui, Guo-xin

    2016-07-15

    Ferroelectric domain inversion and its effect on the stability of lithium niobate thin films on insulator (LNOI) are experimentally characterized. Two sets of specimens with different thicknesses varying from submicron to microns are selected. For micron thick samples (∼28 μm), domain structures are achieved by pulsed electric field poling with electrodes patterned via photolithography. No domain structure deterioration has been observed for a month as inspected using polarizing optical microscopy and etching. As for submicron (540 nm) films, large-area domain inversion is realized by scanning a biased conductive tip in a piezoelectric force microscope. A graphic processing method is takenmore » to evaluate the domain retention. A domain life time of 25.0 h is obtained and possible mechanisms are discussed. Our study gives a direct reference for domain structure-related applications of LNOI, including guiding wave nonlinear frequency conversion, nonlinear wavefront tailoring, electro-optic modulation, and piezoelectric devices.« less

  10. 2D Seismic Imaging of Elastic Parameters by Frequency Domain Full Waveform Inversion

    NASA Astrophysics Data System (ADS)

    Brossier, R.; Virieux, J.; Operto, S.

    2008-12-01

    Thanks to recent advances in parallel computing, full waveform inversion is today a tractable seismic imaging method to reconstruct physical parameters of the earth interior at different scales ranging from the near- surface to the deep crust. We present a massively parallel 2D frequency-domain full-waveform algorithm for imaging visco-elastic media from multi-component seismic data. The forward problem (i.e. the resolution of the frequency-domain 2D PSV elastodynamics equations) is based on low-order Discontinuous Galerkin (DG) method (P0 and/or P1 interpolations). Thanks to triangular unstructured meshes, the DG method allows accurate modeling of both body waves and surface waves in case of complex topography for a discretization of 10 to 15 cells per shear wavelength. The frequency-domain DG system is solved efficiently for multiple sources with the parallel direct solver MUMPS. The local inversion procedure (i.e. minimization of residuals between observed and computed data) is based on the adjoint-state method which allows to efficiently compute the gradient of the objective function. Applying the inversion hierarchically from the low frequencies to the higher ones defines a multiresolution imaging strategy which helps convergence towards the global minimum. In place of expensive Newton algorithm, the combined use of the diagonal terms of the approximate Hessian matrix and optimization algorithms based on quasi-Newton methods (Conjugate Gradient, LBFGS, ...) allows to improve the convergence of the iterative inversion. The distribution of forward problem solutions over processors driven by a mesh partitioning performed by METIS allows to apply most of the inversion in parallel. We shall present the main features of the parallel modeling/inversion algorithm, assess its scalability and illustrate its performances with realistic synthetic case studies.

  11. Bayesian ISOLA: new tool for automated centroid moment tensor inversion

    NASA Astrophysics Data System (ADS)

    Vackář, Jiří; Burjánek, Jan; Gallovič, František; Zahradník, Jiří; Clinton, John

    2017-04-01

    Focal mechanisms are important for understanding seismotectonics of a region, and they serve as a basic input for seismic hazard assessment. Usually, the point source approximation and the moment tensor (MT) are used. We have developed a new, fully automated tool for the centroid moment tensor (CMT) inversion in a Bayesian framework. It includes automated data retrieval, data selection where station components with various instrumental disturbances and high signal-to-noise are rejected, and full-waveform inversion in a space-time grid around a provided hypocenter. The method is innovative in the following aspects: (i) The CMT inversion is fully automated, no user interaction is required, although the details of the process can be visually inspected latter on many figures which are automatically plotted.(ii) The automated process includes detection of disturbances based on MouseTrap code, so disturbed recordings do not affect inversion.(iii) A data covariance matrix calculated from pre-event noise yields an automated weighting of the station recordings according to their noise levels and also serves as an automated frequency filter suppressing noisy frequencies.(iv) Bayesian approach is used, so not only the best solution is obtained, but also the posterior probability density function.(v) A space-time grid search effectively combined with the least-squares inversion of moment tensor components speeds up the inversion and allows to obtain more accurate results compared to stochastic methods. The method has been tested on synthetic and observed data. It has been tested by comparison with manually processed moment tensors of all events greater than M≥3 in the Swiss catalogue over 16 years using data available at the Swiss data center (http://arclink.ethz.ch). The quality of the results of the presented automated process is comparable with careful manual processing of data. The software package programmed in Python has been designed to be as versatile as possible in order to be applicable in various networks ranging from local to regional. The method can be applied either to the everyday network data flow, or to process large previously existing earthquake catalogues and data sets.

  12. Source spectra of the first four Source Physics Experiments (SPE) explosions from the frequency-domain moment-tensor inversion

    DOE PAGES

    Yang, Xiaoning

    2016-08-01

    In this study, I used seismic waveforms recorded within 2 km from the epicenter of the first four Source Physics Experiments (SPE) explosions to invert for the moment-tensor spectra of these explosions. I employed a one-dimensional (1D) Earth model for Green's function calculations. The model was developed from P- and R g-wave travel times and amplitudes. I selected data for the inversion based on the criterion that they had consistent travel times and amplitude behavior as those predicted by the 1D model. Due to limited azimuthal coverage of the sources and the mostly vertical-component-only nature of the dataset, only long-period,more » volumetric components of the moment-tensor spectra were well constrained.« less

  13. Complex Patterns of Local Adaptation in Teosinte

    PubMed Central

    Pyhäjärvi, Tanja; Hufford, Matthew B.; Mezmouk, Sofiane; Ross-Ibarra, Jeffrey

    2013-01-01

    Populations of widely distributed species encounter and must adapt to local environmental conditions. However, comprehensive characterization of the genetic basis of adaptation is demanding, requiring genome-wide genotype data, multiple sampled populations, and an understanding of population structure and potential selection pressures. Here, we used single-nucleotide polymorphism genotyping and data on numerous environmental variables to describe the genetic basis of local adaptation in 21 populations of teosinte, the wild ancestor of maize. We found complex hierarchical genetic structure created by altitude, dispersal events, and admixture among subspecies, which complicated identification of locally beneficial alleles. Patterns of linkage disequilibrium revealed four large putative inversion polymorphisms showing clinal patterns of frequency. Population differentiation and environmental correlations suggest that both inversions and intergenic polymorphisms are involved in local adaptation. PMID:23902747

  14. Soya food intake and risk of endometrial cancer among Chinese women in Shanghai: population based case-control study

    PubMed Central

    Xu, Wang Hong; Zheng, Wei; Xiang, Yong Bing; Ruan, Zhi Xian; Cheng, Jia Rong; Dai, Qi; Gao, Yu Tang; Shu, Xiao Ou

    2004-01-01

    Objective To evaluate the association of intake of soya food, a rich source of phytoestrogens, with the risk of endometrial cancer. Design Population based case-control study, with detailed information on usual soya food intake over the past five years collected by face to face interview using a food frequency questionnaire. Setting Urban Shanghai, China. Participants 832 incident cases of endometrial cancer in women aged of 30 to 69 years diagnosed during 1997-2001 and identified from the Shanghai Cancer Registry; 846 control women frequency matched to cases on age and randomly selected from the Shanghai Residential Registry. Main outcome measures Odds ratios for risk of endometrial cancer in women with different intakes of soya foods. Results Regular consumption of soya foods, measured as amount of either soya protein or soya isoflavones, was inversely associated with the risk of endometrial cancer. Compared with women with the lowest quarter of intake, the adjusted odds ratio of endometrial cancer was reduced from 0.93 to 0.85 and 0.67 with increasing quarter of soya protein intake (P for trend 0.01). A similar inverse association was observed for soya isoflavones and soya fibre intake. The inverse association seemed to be more pronounced among women with high body mass index and waist:hip ratio. Conclusion Regular intake of soya foods is associated with a reduced risk of endometrial cancer. PMID:15136343

  15. Multi-scale signed envelope inversion

    NASA Astrophysics Data System (ADS)

    Chen, Guo-Xin; Wu, Ru-Shan; Wang, Yu-Qing; Chen, Sheng-Chang

    2018-06-01

    Envelope inversion based on modulation signal mode was proposed to reconstruct large-scale structures of underground media. In order to solve the shortcomings of conventional envelope inversion, multi-scale envelope inversion was proposed using new envelope Fréchet derivative and multi-scale inversion strategy to invert strong contrast models. In multi-scale envelope inversion, amplitude demodulation was used to extract the low frequency information from envelope data. However, only to use amplitude demodulation method will cause the loss of wavefield polarity information, thus increasing the possibility of inversion to obtain multiple solutions. In this paper we proposed a new demodulation method which can contain both the amplitude and polarity information of the envelope data. Then we introduced this demodulation method into multi-scale envelope inversion, and proposed a new misfit functional: multi-scale signed envelope inversion. In the numerical tests, we applied the new inversion method to the salt layer model and SEG/EAGE 2-D Salt model using low-cut source (frequency components below 4 Hz were truncated). The results of numerical test demonstrated the effectiveness of this method.

  16. Multi-frequency inversion-charge pumping for charge separation and mobility analysis in high-k/InGaAs metal-oxide-semiconductor field-effect transistors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Djara, V.; Cherkaoui, K.; Negara, M. A.

    2015-11-28

    An alternative multi-frequency inversion-charge pumping (MFICP) technique was developed to directly separate the inversion charge density (N{sub inv}) from the trapped charge density in high-k/InGaAs metal-oxide-semiconductor field-effect transistors (MOSFETs). This approach relies on the fitting of the frequency response of border traps, obtained from inversion-charge pumping measurements performed over a wide range of frequencies at room temperature on a single MOSFET, using a modified charge trapping model. The obtained model yielded the capture time constant and density of border traps located at energy levels aligned with the InGaAs conduction band. Moreover, the combination of MFICP and pulsed I{sub d}-V{sub g}more » measurements enabled an accurate effective mobility vs N{sub inv} extraction and analysis. The data obtained using the MFICP approach are consistent with the most recent reports on high-k/InGaAs.« less

  17. Spontaneous otoacoustic emissions, threshold microstructure, and psychophysical tuning over a wide frequency range in humansa

    PubMed Central

    Baiduc, Rachael R.; Lee, Jungmee; Dhar, Sumitrajit

    2014-01-01

    Hearing thresholds have been shown to exhibit periodic minima and maxima, a pattern known as threshold microstructure. Microstructure has previously been linked to spontaneous otoacoustic emissions (SOAEs) and normal cochlear function. However, SOAEs at high frequencies (>4 kHz) have been associated with hearing loss or cochlear pathology in some reports. Microstructure would not be expected near these high-frequency SOAEs. Psychophysical tuning curves (PTCs), the expression of frequency selectivity, may also be altered by SOAEs. Prior comparisons of tuning between ears with and without SOAEs demonstrated sharper tuning in ears with emissions. Here, threshold microstructure and PTCs were compared at SOAE frequencies ranging between 1.2 and 13.9 kHz using subjects without SOAEs as controls. Results indicate: (1) Threshold microstructure is observable in the vicinity of SOAEs of all frequencies; (2) PTCs are influenced by SOAEs, resulting in shifted tuning curve tips, multiple tips, or inversion. High frequency SOAEs show a greater effect on PTC morphology. The influence of most SOAEs at high frequencies on threshold microstructure and PTCs is consistent with those at lower frequencies, suggesting that high-frequency SOAEs reflect the same cochlear processes that lead to SOAEs at lower frequencies. PMID:24437770

  18. Adiabatic sweep pulses for earth's field NMR with a surface coil

    NASA Astrophysics Data System (ADS)

    Conradi, Mark S.; Altobelli, Stephen A.; Sowko, Nicholas J.; Conradi, Susan H.; Fukushima, Eiichi

    2018-03-01

    Adiabatic NMR sweep pulses are described for inversion and excitation in very low magnetic fields B0 and with broad distribution of excitation field amplitude B1. Two aspects distinguish the low field case: (1) when B1 is comparable to or greater than B0, the rotating field approximation fails and (2) inversion sweeps cannot extend to values well below the Larmor frequency because they would approach or pass through zero frequency. Three approaches to inversion are described. The first is a conventional tangent frequency sweep down to the Larmor frequency, a 180° phase shift, and a sweep back up to the starting frequency. The other two are combined frequency and amplitude sweeps covering a narrower frequency range; one is a symmetric sweep from above to below the Larmor frequency and the other uses a smooth decrease of B1 immediately before and after the 180° phase shift. These two AM/FM sweeps show excellent inversion efficiencies over a wide range of B1, a factor of 30 or more. We also demonstrate an excitation sweep that works well in the presence of the same wide range of B1. We show that the primary effect of the counter-rotating field (i.e., at low B0) is that the magnetization suffers large, periodic deviations from where it would be at large B0. Thus, successful sweep pulses must avoid any sharp features in the amplitude, phase, or frequency.

  19. A flexible, extendable, modular and computationally efficient approach to scattering-integral-based seismic full waveform inversion

    NASA Astrophysics Data System (ADS)

    Schumacher, F.; Friederich, W.; Lamara, S.

    2016-02-01

    We present a new conceptual approach to scattering-integral-based seismic full waveform inversion (FWI) that allows a flexible, extendable, modular and both computationally and storage-efficient numerical implementation. To achieve maximum modularity and extendability, interactions between the three fundamental steps carried out sequentially in each iteration of the inversion procedure, namely, solving the forward problem, computing waveform sensitivity kernels and deriving a model update, are kept at an absolute minimum and are implemented by dedicated interfaces. To realize storage efficiency and maximum flexibility, the spatial discretization of the inverted earth model is allowed to be completely independent of the spatial discretization employed by the forward solver. For computational efficiency reasons, the inversion is done in the frequency domain. The benefits of our approach are as follows: (1) Each of the three stages of an iteration is realized by a stand-alone software program. In this way, we avoid the monolithic, unflexible and hard-to-modify codes that have often been written for solving inverse problems. (2) The solution of the forward problem, required for kernel computation, can be obtained by any wave propagation modelling code giving users maximum flexibility in choosing the forward modelling method. Both time-domain and frequency-domain approaches can be used. (3) Forward solvers typically demand spatial discretizations that are significantly denser than actually desired for the inverted model. Exploiting this fact by pre-integrating the kernels allows a dramatic reduction of disk space and makes kernel storage feasible. No assumptions are made on the spatial discretization scheme employed by the forward solver. (4) In addition, working in the frequency domain effectively reduces the amount of data, the number of kernels to be computed and the number of equations to be solved. (5) Updating the model by solving a large equation system can be done using different mathematical approaches. Since kernels are stored on disk, it can be repeated many times for different regularization parameters without need to solve the forward problem, making the approach accessible to Occam's method. Changes of choice of misfit functional, weighting of data and selection of data subsets are still possible at this stage. We have coded our approach to FWI into a program package called ASKI (Analysis of Sensitivity and Kernel Inversion) which can be applied to inverse problems at various spatial scales in both Cartesian and spherical geometries. It is written in modern FORTRAN language using object-oriented concepts that reflect the modular structure of the inversion procedure. We validate our FWI method by a small-scale synthetic study and present first results of its application to high-quality seismological data acquired in the southern Aegean.

  20. Remote sounding of cloudy atmospheres. I - The single cloud layer

    NASA Technical Reports Server (NTRS)

    Chahine, M. T.

    1974-01-01

    The relaxation method for the inverse solution of the radiative transfer equation is applied in a dual-frequency scheme for the determination of complete vertical temperature profiles in cloudy atmospheres from radiance observations alone, without any additional information related to the expected solutions. The dual-frequency principle employs to advantage a property in the Planck function of the dependence of intensity on frequency. This property leads to the formulation of a new convergence criterion for the selection of cloud-sounding frequencies to be used for reconstructing the clear column radiance from observations made in the presence of a broken cloud layer in all fields of view. The principle is applied to the case of observations in two adjacent or partially overlapping fields of view and to the case of observations in a single field of view. The solutions are illustrated by numerical examples in the dual-frequency ranges of the 4.3 and 15-micron CO2 bands of the terrestrial atmosphere.

  1. Time-domain wavefield reconstruction inversion

    NASA Astrophysics Data System (ADS)

    Li, Zhen-Chun; Lin, Yu-Zhao; Zhang, Kai; Li, Yuan-Yuan; Yu, Zhen-Nan

    2017-12-01

    Wavefield reconstruction inversion (WRI) is an improved full waveform inversion theory that has been proposed in recent years. WRI method expands the searching space by introducing the wave equation into the objective function and reconstructing the wavefield to update model parameters, thereby improving the computing efficiency and mitigating the influence of the local minimum. However, frequency-domain WRI is difficult to apply to real seismic data because of the high computational memory demand and requirement of time-frequency transformation with additional computational costs. In this paper, wavefield reconstruction inversion theory is extended into the time domain, the augmented wave equation of WRI is derived in the time domain, and the model gradient is modified according to the numerical test with anomalies. The examples of synthetic data illustrate the accuracy of time-domain WRI and the low dependency of WRI on low-frequency information.

  2. Visco-elastic controlled-source full waveform inversion without surface waves

    NASA Astrophysics Data System (ADS)

    Paschke, Marco; Krause, Martin; Bleibinhaus, Florian

    2016-04-01

    We developed a frequency-domain visco-elastic full waveform inversion for onshore seismic experiments with topography. The forward modeling is based on a finite-difference time-domain algorithm by Robertsson that uses the image-method to ensure a stress-free condition at the surface. The time-domain data is Fourier-transformed at every point in the model space during the forward modeling for a given set of frequencies. The motivation for this approach is the reduced amount of memory when computing kernels, and the straightforward implementation of the multiscale approach. For the inversion, we calculate the Frechet derivative matrix explicitly, and we implement a Levenberg-Marquardt scheme that allows for computing the resolution matrix. To reduce the size of the Frechet derivative matrix, and to stabilize the inversion, an adapted inverse mesh is used. The node spacing is controlled by the velocity distribution and the chosen frequencies. To focus the inversion on body waves (P, P-coda, and S) we mute the surface waves from the data. Consistent spatiotemporal weighting factors are applied to the wavefields during the Fourier transform to obtain the corresponding kernels. We test our code with a synthetic study using the Marmousi model with arbitrary topography. This study also demonstrates the importance of topography and muting surface waves in controlled-source full waveform inversion.

  3. Spatially constrained Bayesian inversion of frequency- and time-domain electromagnetic data from the Tellus projects

    NASA Astrophysics Data System (ADS)

    Kiyan, Duygu; Rath, Volker; Delhaye, Robert

    2017-04-01

    The frequency- and time-domain airborne electromagnetic (AEM) data collected under the Tellus projects of the Geological Survey of Ireland (GSI) which represent a wealth of information on the multi-dimensional electrical structure of Ireland's near-surface. Our project, which was funded by GSI under the framework of their Short Call Research Programme, aims to develop and implement inverse techniques based on various Bayesian methods for these densely sampled data. We have developed a highly flexible toolbox using Python language for the one-dimensional inversion of AEM data along the flight lines. The computational core is based on an adapted frequency- and time-domain forward modelling core derived from the well-tested open-source code AirBeo, which was developed by the CSIRO (Australia) and the AMIRA consortium. Three different inversion methods have been implemented: (i) Tikhonov-type inversion including optimal regularisation methods (Aster el al., 2012; Zhdanov, 2015), (ii) Bayesian MAP inversion in parameter and data space (e.g. Tarantola, 2005), and (iii) Full Bayesian inversion with Markov Chain Monte Carlo (Sambridge and Mosegaard, 2002; Mosegaard and Sambridge, 2002), all including different forms of spatial constraints. The methods have been tested on synthetic and field data. This contribution will introduce the toolbox and present case studies on the AEM data from the Tellus projects.

  4. Multi-scale Slip Inversion Based on Simultaneous Spatial and Temporal Domain Wavelet Transform

    NASA Astrophysics Data System (ADS)

    Liu, W.; Yao, H.; Yang, H. Y.

    2017-12-01

    Finite fault inversion is a widely used method to study earthquake rupture processes. Some previous studies have proposed different methods to implement finite fault inversion, including time-domain, frequency-domain, and wavelet-domain methods. Many previous studies have found that different frequency bands show different characteristics of the seismic rupture (e.g., Wang and Mori, 2011; Yao et al., 2011, 2013; Uchide et al., 2013; Yin et al., 2017). Generally, lower frequency waveforms correspond to larger-scale rupture characteristics while higher frequency data are representative of smaller-scale ones. Therefore, multi-scale analysis can help us understand the earthquake rupture process thoroughly from larger scale to smaller scale. By the use of wavelet transform, the wavelet-domain methods can analyze both the time and frequency information of signals in different scales. Traditional wavelet-domain methods (e.g., Ji et al., 2002) implement finite fault inversion with both lower and higher frequency signals together to recover larger-scale and smaller-scale characteristics of the rupture process simultaneously. Here we propose an alternative strategy with a two-step procedure, i.e., firstly constraining the larger-scale characteristics with lower frequency signals, and then resolving the smaller-scale ones with higher frequency signals. We have designed some synthetic tests to testify our strategy and compare it with the traditional one. We also have applied our strategy to study the 2015 Gorkha Nepal earthquake using tele-seismic waveforms. Both the traditional method and our two-step strategy only analyze the data in different temporal scales (i.e., different frequency bands), while the spatial distribution of model parameters also shows multi-scale characteristics. A more sophisticated strategy is to transfer the slip model into different spatial scales, and then analyze the smooth slip distribution (larger scales) with lower frequency data firstly and more detailed slip distribution (smaller scales) with higher frequency data subsequently. We are now implementing the slip inversion using both spatial and temporal domain wavelets. This multi-scale analysis can help us better understand frequency-dependent rupture characteristics of large earthquakes.

  5. Large-scale analyses of synonymous substitution rates can be sensitive to assumptions about the process of mutation.

    PubMed

    Aris-Brosou, Stéphane; Bielawski, Joseph P

    2006-08-15

    A popular approach to examine the roles of mutation and selection in the evolution of genomes has been to consider the relationship between codon bias and synonymous rates of molecular evolution. A significant relationship between these two quantities is taken to indicate the action of weak selection on substitutions among synonymous codons. The neutral theory predicts that the rate of evolution is inversely related to the level of functional constraint. Therefore, selection against the use of non-preferred codons among those coding for the same amino acid should result in lower rates of synonymous substitution as compared with sites not subject to such selection pressures. However, reliably measuring the extent of such a relationship is problematic, as estimates of synonymous rates are sensitive to our assumptions about the process of molecular evolution. Previous studies showed the importance of accounting for unequal codon frequencies, in particular when synonymous codon usage is highly biased. Yet, unequal codon frequencies can be modeled in different ways, making different assumptions about the mutation process. Here we conduct a simulation study to evaluate two different ways of modeling uneven codon frequencies and show that both model parameterizations can have a dramatic impact on rate estimates and affect biological conclusions about genome evolution. We reanalyze three large data sets to demonstrate the relevance of our results to empirical data analysis.

  6. Design of dual band FSS by using quadruple L-slot technique

    NASA Astrophysics Data System (ADS)

    Fauzi, Noor Azamiah Md; Aziz, Mohamad Zoinol Abidin Abd.; Said, Maizatul Alice Meor; Othman, Mohd Azlishah; Ahmad, Badrul Hisham; Malek, Mohd Fareq Abd

    2015-05-01

    This paper presents a new design of dual band frequency selective surface (FSS) for band pass microwave transmission application. FSS can be used on energy saving glass to improve the transmission of wireless communication signals through the glass. The microwave signal will be attenuate when propagate throughout the different structure such as building. Therefore, some of the wireless communication system cannot be used in the optimum performance. The aim of this paper is designed, simulated and analyzed the new dual band FSS structure for microwave transmission. This design is based on a quadruple L slot combined with cross slot to produce pass band at 900 MHz and 2.4 GHz. The vertical of pair inverse L slot is used as the band pass for the frequency of 2.4GHz. While, the horizontal of pair inverse L slot is used as the band pass at frequency 900MHz. This design is simulated and analyzed by using Computer Simulation Technology (CST) Microwave Studio (MWS) software. The characteristics of the transmission (S21) and reflection (S11) of the dual band FSS were simulater and analyzed. The bandwidth of the first band is 118.91MHz which covered the frequency range from 833.4MHz until 952.31MHz. Meanwhile, the bandwidth for the second band is 358.84MHz which covered the frequency range from 2.1475GHz until 2.5063GHz. The resonance/center frequency of this design is obtained at 900MHz with a 26.902dB return loss and 2.37GHz with 28.506dB a return loss. This FSS is suitable as microwave filter for GSM900 and WLAN 2.4GHz application.

  7. Feature extraction for document text using Latent Dirichlet Allocation

    NASA Astrophysics Data System (ADS)

    Prihatini, P. M.; Suryawan, I. K.; Mandia, IN

    2018-01-01

    Feature extraction is one of stages in the information retrieval system that used to extract the unique feature values of a text document. The process of feature extraction can be done by several methods, one of which is Latent Dirichlet Allocation. However, researches related to text feature extraction using Latent Dirichlet Allocation method are rarely found for Indonesian text. Therefore, through this research, a text feature extraction will be implemented for Indonesian text. The research method consists of data acquisition, text pre-processing, initialization, topic sampling and evaluation. The evaluation is done by comparing Precision, Recall and F-Measure value between Latent Dirichlet Allocation and Term Frequency Inverse Document Frequency KMeans which commonly used for feature extraction. The evaluation results show that Precision, Recall and F-Measure value of Latent Dirichlet Allocation method is higher than Term Frequency Inverse Document Frequency KMeans method. This shows that Latent Dirichlet Allocation method is able to extract features and cluster Indonesian text better than Term Frequency Inverse Document Frequency KMeans method.

  8. A Space-Time-Frequency Dictionary for Sparse Cortical Source Localization.

    PubMed

    Korats, Gundars; Le Cam, Steven; Ranta, Radu; Louis-Dorr, Valerie

    2016-09-01

    Cortical source imaging aims at identifying activated cortical areas on the surface of the cortex from the raw electroencephalogram (EEG) data. This problem is ill posed, the number of channels being very low compared to the number of possible source positions. In some realistic physiological situations, the active areas are sparse in space and of short time durations, and the amount of spatio-temporal data to carry the inversion is then limited. In this study, we propose an original data driven space-time-frequency (STF) dictionary which takes into account simultaneously both spatial and time-frequency sparseness while preserving smoothness in the time frequency (i.e., nonstationary smooth time courses in sparse locations). Based on these assumptions, we take benefit of the matching pursuit (MP) framework for selecting the most relevant atoms in this highly redundant dictionary. We apply two recent MP algorithms, single best replacement (SBR) and source deflated matching pursuit, and we compare the results using a spatial dictionary and the proposed STF dictionary to demonstrate the improvements of our multidimensional approach. We also provide comparison using well-established inversion methods, FOCUSS and RAP-MUSIC, analyzing performances under different degrees of nonstationarity and signal to noise ratio. Our STF dictionary combined with the SBR approach provides robust performances on realistic simulations. From a computational point of view, the algorithm is embedded in the wavelet domain, ensuring high efficiency in term of computation time. The proposed approach ensures fast and accurate sparse cortical localizations on highly nonstationary and noisy data.

  9. FWT2D: A massively parallel program for frequency-domain full-waveform tomography of wide-aperture seismic data—Part 1: Algorithm

    NASA Astrophysics Data System (ADS)

    Sourbier, Florent; Operto, Stéphane; Virieux, Jean; Amestoy, Patrick; L'Excellent, Jean-Yves

    2009-03-01

    This is the first paper in a two-part series that describes a massively parallel code that performs 2D frequency-domain full-waveform inversion of wide-aperture seismic data for imaging complex structures. Full-waveform inversion methods, namely quantitative seismic imaging methods based on the resolution of the full wave equation, are computationally expensive. Therefore, designing efficient algorithms which take advantage of parallel computing facilities is critical for the appraisal of these approaches when applied to representative case studies and for further improvements. Full-waveform modelling requires the resolution of a large sparse system of linear equations which is performed with the massively parallel direct solver MUMPS for efficient multiple-shot simulations. Efficiency of the multiple-shot solution phase (forward/backward substitutions) is improved by using the BLAS3 library. The inverse problem relies on a classic local optimization approach implemented with a gradient method. The direct solver returns the multiple-shot wavefield solutions distributed over the processors according to a domain decomposition driven by the distribution of the LU factors. The domain decomposition of the wavefield solutions is used to compute in parallel the gradient of the objective function and the diagonal Hessian, this latter providing a suitable scaling of the gradient. The algorithm allows one to test different strategies for multiscale frequency inversion ranging from successive mono-frequency inversion to simultaneous multifrequency inversion. These different inversion strategies will be illustrated in the following companion paper. The parallel efficiency and the scalability of the code will also be quantified.

  10. A parametric study of motor starting for a 2- to 10-kilowatt Brayton power system

    NASA Technical Reports Server (NTRS)

    Cantoni, D. A.

    1971-01-01

    A study of the motor starting of a Brayton cycle power system was conducted to provide estimates of system sensitivity to several controllable parameters. These sensitivity estimates were used as a basis for selection of an optimum motor-start scheme to be implemented on the 2- to 10-kilowatt Brayton power system designed and presently under test. The studies were conducted with an analog simulation of the Brayton power system and covered a range of frequencies from 400 Hz (33 percent design) to 1200 Hz (design), voltage-to-frequency ratios of 0.050 (50 percent design) to 0.100 (design), turbine-inlet temperatures of 800 K (1440 R, 70 percent design) to 1140 K (2060 deg R, design), and prestart pressure levels of 14.5 psia to 29.0 psia. These studies have shown the effect of selected system variables on motor starting. The final selection of motor-start variables can therefore be made on the basis of motor-start inverter complexity, battery size and weight, desired steady-state pressure level after startup, and other operational limitations. In general, the study showed the time required for motor starting to be inversely proportional to motor frequency, voltage, turbine-inlet temperature, and pressure level. An increase in any of these parameters decreases startup time.

  11. Chemical Exchange Saturation Transfer (CEST): what is in a name and what isn’t?

    PubMed Central

    van Zijl, Peter C.M.; Yadav, Nirbhay N.

    2011-01-01

    Chemical exchange saturation transfer (CEST) imaging is a relatively new MRI contrast approach in which exogenous or endogenous compounds containing either exchangeable protons or exchangeable molecules are selectively saturated and, after transfer of this saturation, detected indirectly through the water signal with enhanced sensitivity. The focus of this review is on basic MR principles underlying CEST and similarities to and differences with conventional magnetization transfer contrast (MTC). In CEST MRI, transfer of magnetization is studied in mobile compounds instead of semisolids. Similar to MTC, CEST has contributions of both chemical exchange and dipolar cross-relaxation, but the latter can often be neglected if exchange is fast. Contrary to MTC, CEST imaging requires sufficiently slow exchange on the MR time scale to allow selective irradiation of the protons of interest. As a consequence, magnetic labeling is not limited to radio-frequency saturation but can be expanded with slower frequency-selective approaches such as inversion, gradient dephasing and frequency labeling. The basic theory, design criteria, and experimental issues for exchange transfer imaging are discussed. A new classification for CEST agents based on exchange type is proposed. The potential of this young field is discussed, especially with respect to in vivo application and translation to humans. PMID:21337419

  12. Frequencies of chromosomal inversions in Drosophila melanogaster in Fukushima after the nuclear power plant accident.

    PubMed

    Itoh, Masanobu; Kajihara, Ryutaro; Kato, Yasuko; Takano-Shimizu, Toshiyuki; Inoue, Yutaka

    2018-01-01

    In order to investigate genetic impact of a large amount of radionuclides released by the Fukushima Dai-ichi Nuclear Power Plant accident in 2011, we surveyed 2,304 haploid genomes of Drosophila melanogaster collected in three localities in Fukushima in 2012 and 2013 for chromosomal inversions. No unique inversion was found in 298 genomes in 2012 and only two in 2,006 genomes in 2013. The observed frequencies were even lower than the long-term average frequency of unique inversions in Japan. The common cosmopolitan inversions were also examined in Fukushima, Kyoto, and Iriomote (Okinawa) in 2012. Among three samples in Fukushima, the flies in Iizaka, where environmental radiation level was the highest, showed the lowest frequency of In(2L)t, but the highest frequency of In(3R)P, contrary to the expectation of decreasing of their frequencies in higher polluted areas. These results suggest that, at this level of genetic analysis, Fukushima populations of D. melanogaster would not have been negatively impacted following the release of radionuclides. Transposable P-element mobility was not likely to induce DNA damage solely or synergistically with radioactivity, because their transposition activity was totally repressed in the Fukushima strains. However, it should be noted that, because of limitations in access to the exclusion zone, we could only sample the populations in areas of relatively low radioactive contamination (0.39-0.63 μSv/h). Therefore, the present study is likely to be underpowered to detect any effects that might be expected in heavily contaminated areas.

  13. Frequencies of chromosomal inversions in Drosophila melanogaster in Fukushima after the nuclear power plant accident

    PubMed Central

    Kajihara, Ryutaro; Kato, Yasuko; Takano-Shimizu, Toshiyuki; Inoue, Yutaka

    2018-01-01

    In order to investigate genetic impact of a large amount of radionuclides released by the Fukushima Dai-ichi Nuclear Power Plant accident in 2011, we surveyed 2,304 haploid genomes of Drosophila melanogaster collected in three localities in Fukushima in 2012 and 2013 for chromosomal inversions. No unique inversion was found in 298 genomes in 2012 and only two in 2,006 genomes in 2013. The observed frequencies were even lower than the long-term average frequency of unique inversions in Japan. The common cosmopolitan inversions were also examined in Fukushima, Kyoto, and Iriomote (Okinawa) in 2012. Among three samples in Fukushima, the flies in Iizaka, where environmental radiation level was the highest, showed the lowest frequency of In(2L)t, but the highest frequency of In(3R)P, contrary to the expectation of decreasing of their frequencies in higher polluted areas. These results suggest that, at this level of genetic analysis, Fukushima populations of D. melanogaster would not have been negatively impacted following the release of radionuclides. Transposable P-element mobility was not likely to induce DNA damage solely or synergistically with radioactivity, because their transposition activity was totally repressed in the Fukushima strains. However, it should be noted that, because of limitations in access to the exclusion zone, we could only sample the populations in areas of relatively low radioactive contamination (0.39–0.63 μSv/h). Therefore, the present study is likely to be underpowered to detect any effects that might be expected in heavily contaminated areas. PMID:29420572

  14. Adaptive Inverse Control for Rotorcraft Vibration Reduction

    NASA Technical Reports Server (NTRS)

    Jacklin, Stephen A.

    1985-01-01

    This thesis extends the Least Mean Square (LMS) algorithm to solve the mult!ple-input, multiple-output problem of alleviating N/Rev (revolutions per minute by number of blades) helicopter fuselage vibration by means of adaptive inverse control. A frequency domain locally linear model is used to represent the transfer matrix relating the higher harmonic pitch control inputs to the harmonic vibration outputs to be controlled. By using the inverse matrix as the controller gain matrix, an adaptive inverse regulator is formed to alleviate the N/Rev vibration. The stability and rate of convergence properties of the extended LMS algorithm are discussed. It is shown that the stability ranges for the elements of the stability gain matrix are directly related to the eigenvalues of the vibration signal information matrix for the learning phase, but not for the control phase. The overall conclusion is that the LMS adaptive inverse control method can form a robust vibration control system, but will require some tuning of the input sensor gains, the stability gain matrix, and the amount of control relaxation to be used. The learning curve of the controller during the learning phase is shown to be quantitatively close to that predicted by averaging the learning curves of the normal modes. For higher order transfer matrices, a rough estimate of the inverse is needed to start the algorithm efficiently. The simulation results indicate that the factor which most influences LMS adaptive inverse control is the product of the control relaxation and the the stability gain matrix. A small stability gain matrix makes the controller less sensitive to relaxation selection, and permits faster and more stable vibration reduction, than by choosing the stability gain matrix large and the control relaxation term small. It is shown that the best selections of the stability gain matrix elements and the amount of control relaxation is basically a compromise between slow, stable convergence and fast convergence with increased possibility of unstable identification. In the simulation studies, the LMS adaptive inverse control algorithm is shown to be capable of adapting the inverse (controller) matrix to track changes in the flight conditions. The algorithm converges quickly for moderate disturbances, while taking longer for larger disturbances. Perfect knowledge of the inverse matrix is not required for good control of the N/Rev vibration. However it is shown that measurement noise will prevent the LMS adaptive inverse control technique from controlling the vibration, unless the signal averaging method presented is incorporated into the algorithm.

  15. Rapid kinematic finite source inversion for Tsunamic Early Warning using high rate GNSS data

    NASA Astrophysics Data System (ADS)

    Chen, K.; Liu, Z.; Song, Y. T.

    2017-12-01

    Recently, Global Navigation Satellite System (GNSS) has been used for rapid earthquake source inversion towards tsunami early warning. In practice, two approaches, i.e., static finite source inversion based on permanent co-seismic offsets and kinematic finite source inversion using high-rate (>= 1 Hz) co-seismic displacement waveforms, are often employed to fulfill the task. The static inversion is relatively easy to be implemented and does not require additional constraints on rupture velocity, duration, and temporal variation. However, since most GNSS receivers are deployed onshore locating on one side of the subduction fault, there is very limited resolution on near-trench fault slip using GNSS in static finite source inversion. On the other hand, the high-rate GNSS displacement waveforms, which contain the timing information of earthquake rupture explicitly and static offsets implicitly, have the potential to improve near-trench resolution by reconciling with the depth-dependent megathrust rupture behaviors. In this contribution, we assess the performance of rapid kinematic finite source inversion using high-rate GNSS by three selected historical tsunamigenic cases: the 2010 Mentawai, 2011 Tohoku and 2015 Illapel events. With respect to the 2010 Mentawai case, it is a typical tsunami earthquake with most slip concentrating near the trench. The static inversion has little resolution there and incorrectly puts slip at greater depth (>10km). In contrast, the recorded GNSS displacement waveforms are deficit in high-frequency energy, the kinematic source inversion recovers a shallow slip patch (depth less than 6 km) and tsunami runups are predicted quite reasonably. For the other two events, slip from kinematic and static inversion show similar characteristics and comparable tsunami scenarios, which may be related to dense GNSS network and behavior of the rupture. Acknowledging the complexity of kinematic source inversion in real-time, we adopt the back-projection approach to provide constraint on rupture velocity.

  16. The inverse problem of sensing the mass and force induced by an adsorbate on a beam nanomechanical resonator

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Liu, Yun; Zhang, Yin

    2016-06-08

    The mass sensing superiority of a micro/nanomechanical resonator sensor over conventional mass spectrometry has been, or at least, is being firmly established. Because the sensing mechanism of a mechanical resonator sensor is the shifts of resonant frequencies, how to link the shifts of resonant frequencies with the material properties of an analyte formulates an inverse problem. Besides the analyte/adsorbate mass, many other factors such as position and axial force can also cause the shifts of resonant frequencies. The in-situ measurement of the adsorbate position and axial force is extremely difficult if not impossible, especially when an adsorbate is as smallmore » as a molecule or an atom. Extra instruments are also required. In this study, an inverse problem of using three resonant frequencies to determine the mass, position and axial force is formulated and solved. The accuracy of the inverse problem solving method is demonstrated and how the method can be used in the real application of a nanomechanical resonator is also discussed. Solving the inverse problem is helpful to the development and application of mechanical resonator sensor on two things: reducing extra experimental equipments and achieving better mass sensing by considering more factors.« less

  17. Anopheles darlingi polytene chromosomes: revised maps including newly described inversions and evidence for population structure in Manaus

    PubMed Central

    Cornel, Anthony J; Brisco, Katherine K; Tadei, Wanderli P; Secundino, Nágila FC; Rafael, Miriam S; Galardo, Allan KR; Medeiros, Jansen F; Pessoa, Felipe AC; Ríos-Velásquez, Claudia M; Lee, Yoosook; Pimenta, Paulo FP; Lanzaro, Gregory C

    2016-01-01

    Salivary gland polytene chromosomes of 4th instar Anopheles darlingi Root were examined from multiple locations in the Brazilian Amazon. Minor modifications were made to existing polytene photomaps. These included changes to the breakpoint positions of several previously described paracentric inversions and descriptions of four new paracentric inversions, two on the right arm of chromosome 3 and two on the left arm of chromosome 3 that were found in multiple locations. A total of 18 inversions on the X (n = 1) chromosome, chromosome 2 (n = 7) and 3 (n = 11) were scored for 83 individuals from Manaus, Macapá and Porto Velho municipalities. The frequency of 2Ra inversion karyotypes in Manaus shows significant deficiency of heterozygotes (p < 0.0009). No significant linkage disequilibrium was found between inversions on chromosome 2 and 3. We hypothesize that at least two sympatric subpopulations exist within the An. darlingi population at Manaus based on inversion frequencies. PMID:27223867

  18. ''1/f noise'' in music: Music from 1/f noise

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Voss, R.F.; Clarke, J.

    1978-01-01

    The spectral density of fluctuations in the audio power of many musical selections and of English speech varies approximately as 1/f (f is the frequency) down to a frequency of 5 x 10/sup -4/ Hz. This result implies that the audio-power fluctuations are correlated over all times in the same manner as ''1/f noise'' in electronic components. The frequency fluctuations of music also have a 1/f spectral density at frequencies down to the inverse of the length of the piece of music. The frequency fluctuations of English speech have a quite different behavior, with a single characteristic time of aboutmore » 0.1 s, the average length of a syllable. The observations on music suggest that 1/f noise is a good choice for stochastic composition. Compositions in which the frequency and duration of each note were determined by 1/f noise sources sounded pleasing. Those generated by white-noise sources sounded too random, while those generated by 1/f/sup 2/ noise sounded too correlated.« less

  19. Self Consistent Ambipolar Transport and High Frequency Oscillatory Transient in Graphene Electronics

    DTIC Science & Technology

    2015-08-17

    study showed that in the presence of an ac field, THz oscillations exhibit soft resonances at a frequency roughly equal to half of the inverse of the ...exhibit soft resonances at a frequency roughly equal to half of the inverse of the carrier transit time to the LO phonon energy. It also showed that in...carriers in graphene undergo an anomalous parametric resonance. Such resonance occurs at about half the frequency ωF = 2πeF/~ωOP , where 2π/ωF is the time

  20. Frequency Domain Full-Waveform Inversion in Imaging Thrust Related Features

    NASA Astrophysics Data System (ADS)

    Jaiswal, P.; Zelt, C. A.

    2010-12-01

    Seismic acquisition in rough terrain such as mountain belts suffers from problems related to near-surface conditions such as statics, inconsistent energy penetration, rapid decay of signal, and imperfect receiver coupling. Moreover in the presence of weakly compacted soil, strong ground roll may obscure the reflection arrivals at near offsets further diminishing the scope of estimating a reliable near surface image though conventional processing. Traveltime and waveform inversion not only overcome the simplistic assumptions inherent in conventional processing such as hyperbolic moveout and convolution model, but also use parts of the seismic coda, such as the direct arrival and refractions, that are discarded in the latter. Traveltime and waveform inversion are model-based methods that honour the physics of wave propagation. Given the right set of preconditioned data and starting model, waveform inversion in particular has been realized as a powerful tool for velocity model building. This paper examines two case studies on waveform inversion using real data from the Naga Thrust Belt in the Northeast India. Waveform inversion in this paper is performed in the frequency domain and is multiscale in nature i.e., the inversion progressively ascends from the lower to the higher end of the frequency spectra increasing the wavenumber content of the recovered model. Since the real data are band limited, the success of waveform inversion depends on how well the starting model can account for the missing low wavenumbers. In this paper it is observed that the required starting model can be prepared using the regularized inversion of direct and reflected arrival times.

  1. Modeling analysis of pulsed magnetization process of magnetic core based on inverse Jiles-Atherton model

    NASA Astrophysics Data System (ADS)

    Liu, Yi; Zhang, He; Liu, Siwei; Lin, Fuchang

    2018-05-01

    The J-A (Jiles-Atherton) model is widely used to describe the magnetization characteristics of magnetic cores in a low-frequency alternating field. However, this model is deficient in the quantitative analysis of the eddy current loss and residual loss in a high-frequency magnetic field. Based on the decomposition of magnetization intensity, an inverse J-A model is established which uses magnetic flux density B as an input variable. Static and dynamic core losses under high frequency excitation are separated based on the inverse J-A model. Optimized parameters of the inverse J-A model are obtained based on particle swarm optimization. The platform for the pulsed magnetization characteristic test is designed and constructed. The hysteresis curves of ferrite and Fe-based nanocrystalline cores at high magnetization rates are measured. The simulated and measured hysteresis curves are presented and compared. It is found that the inverse J-A model can be used to describe the magnetization characteristics at high magnetization rates and to separate the static loss and dynamic loss accurately.

  2. High-resolution near-surface velocity model building using full-waveform inversion—a case study from southwest Sweden

    NASA Astrophysics Data System (ADS)

    Adamczyk, A.; Malinowski, M.; Malehmir, A.

    2014-06-01

    Full-waveform inversion (FWI) is an iterative optimization technique that provides high-resolution models of subsurface properties. Frequency-domain, acoustic FWI was applied to seismic data acquired over a known quick-clay landslide scar in southwest Sweden. We inverted data from three 2-D seismic profiles, 261-572 m long, two of them shot with small charges of dynamite and one with a sledgehammer. To our best knowledge this is the first published application of FWI to sledgehammer data. Both sources provided data suitable for waveform inversion, the sledgehammer data containing even wider frequency spectrum. Inversion was performed for frequency groups between 27.5 and 43.1 Hz for the explosive data and 27.5-51.0 Hz for the sledgehammer. The lowest inverted frequency was limited by the resonance frequency of the standard 28-Hz geophones used in the survey. High-velocity granitic bedrock in the area is undulated and very shallow (15-100 m below the surface), and exhibits a large P-wave velocity contrast to the overlying normally consolidated sediments. In order to mitigate the non-linearity of the inverse problem we designed a multiscale layer-stripping inversion strategy. Obtained P-wave velocity models allowed to delineate the top of the bedrock and revealed distinct layers within the overlying sediments of clays and coarse-grained materials. Models were verified in an extensive set of validating procedures and used for pre-stack depth migration, which confirmed their robustness.

  3. Three-dimensional inverse modelling of damped elastic wave propagation in the Fourier domain

    NASA Astrophysics Data System (ADS)

    Petrov, Petr V.; Newman, Gregory A.

    2014-09-01

    3-D full waveform inversion (FWI) of seismic wavefields is routinely implemented with explicit time-stepping simulators. A clear advantage of explicit time stepping is the avoidance of solving large-scale implicit linear systems that arise with frequency domain formulations. However, FWI using explicit time stepping may require a very fine time step and (as a consequence) significant computational resources and run times. If the computational challenges of wavefield simulation can be effectively handled, an FWI scheme implemented within the frequency domain utilizing only a few frequencies, offers a cost effective alternative to FWI in the time domain. We have therefore implemented a 3-D FWI scheme for elastic wave propagation in the Fourier domain. To overcome the computational bottleneck in wavefield simulation, we have exploited an efficient Krylov iterative solver for the elastic wave equations approximated with second and fourth order finite differences. The solver does not exploit multilevel preconditioning for wavefield simulation, but is coupled efficiently to the inversion iteration workflow to reduce computational cost. The workflow is best described as a series of sequential inversion experiments, where in the case of seismic reflection acquisition geometries, the data has been laddered such that we first image highly damped data, followed by data where damping is systemically reduced. The key to our modelling approach is its ability to take advantage of solver efficiency when the elastic wavefields are damped. As the inversion experiment progresses, damping is significantly reduced, effectively simulating non-damped wavefields in the Fourier domain. While the cost of the forward simulation increases as damping is reduced, this is counterbalanced by the cost of the outer inversion iteration, which is reduced because of a better starting model obtained from the larger damped wavefield used in the previous inversion experiment. For cross-well data, it is also possible to launch a successful inversion experiment without laddering the damping constants. With this type of acquisition geometry, the solver is still quite effective using a small fixed damping constant. To avoid cycle skipping, we also employ a multiscale imaging approach, in which frequency content of the data is also laddered (with the data now including both reflection and cross-well data acquisition geometries). Thus the inversion process is launched using low frequency data to first recover the long spatial wavelength of the image. With this image as a new starting model, adding higher frequency data refines and enhances the resolution of the image. FWI using laddered frequencies with an efficient damping schemed enables reconstructing elastic attributes of the subsurface at a resolution that approaches half the smallest wavelength utilized to image the subsurface. We show the possibility of effectively carrying out such reconstructions using two to six frequencies, depending upon the application. Using the proposed FWI scheme, massively parallel computing resources are essential for reasonable execution times.

  4. Terahertz lasers and amplifiers based on resonant optical phonon scattering to achieve population inversion

    NASA Technical Reports Server (NTRS)

    Hu, Qing (Inventor); Williams, Benjamin S. (Inventor)

    2007-01-01

    The present invention provides quantum cascade lasers and amplifier that operate in a frequency range of about 1 Terahertz to about 10 Terahertz. In one aspect, a quantum cascade laser of the invention includes a semiconductor heterostructure that provides a plurality of lasing modules connected in series. Each lasing module includes a plurality of quantum well structure that collectively generate at least an upper lasing state, a lower lasing state, and a relaxation state such that the upper and the lower lasing states are separated by an energy corresponding to an optical frequency in a range of about 1 to about 10 Terahertz. The lower lasing state is selectively depopulated via resonant LO-phonon scattering of electrons into the relaxation state.

  5. Terahertz lasers and amplifiers based on resonant optical phonon scattering to achieve population inversion

    NASA Technical Reports Server (NTRS)

    Williams, Benjamin S. (Inventor); Hu, Qing (Inventor)

    2009-01-01

    The present invention provides quantum cascade lasers and amplifier that operate in a frequency range of about 1 Terahertz to about 10 Terahertz. In one aspect, a quantum cascade laser of the invention includes a semiconductor heterostructure that provides a plurality of lasing modules connected in series. Each lasing module includes a plurality of quantum well structure that collectively generate at least an upper lasing state, a lower lasing state, and a relaxation state such that the upper and the lower lasing states are separated by an energy corresponding to an optical frequency in a range of about 1 to about 10 Terahertz. The lower lasing state is selectively depopulated via resonant LO-phonon scattering of electrons into the relaxation state.

  6. Resolution analysis of marine seismic full waveform data by Bayesian inversion

    NASA Astrophysics Data System (ADS)

    Ray, A.; Sekar, A.; Hoversten, G. M.; Albertin, U.

    2015-12-01

    The Bayesian posterior density function (PDF) of earth models that fit full waveform seismic data convey information on the uncertainty with which the elastic model parameters are resolved. In this work, we apply the trans-dimensional reversible jump Markov Chain Monte Carlo method (RJ-MCMC) for the 1D inversion of noisy synthetic full-waveform seismic data in the frequency-wavenumber domain. While seismic full waveform inversion (FWI) is a powerful method for characterizing subsurface elastic parameters, the uncertainty in the inverted models has remained poorly known, if at all and is highly initial model dependent. The Bayesian method we use is trans-dimensional in that the number of model layers is not fixed, and flexible such that the layer boundaries are free to move around. The resulting parameterization does not require regularization to stabilize the inversion. Depth resolution is traded off with the number of layers, providing an estimate of uncertainty in elastic parameters (compressional and shear velocities Vp and Vs as well as density) with depth. We find that in the absence of additional constraints, Bayesian inversion can result in a wide range of posterior PDFs on Vp, Vs and density. These PDFs range from being clustered around the true model, to those that contain little resolution of any particular features other than those in the near surface, depending on the particular data and target geometry. We present results for a suite of different frequencies and offset ranges, examining the differences in the posterior model densities thus derived. Though these results are for a 1D earth, they are applicable to areas with simple, layered geology and provide valuable insight into the resolving capabilities of FWI, as well as highlight the challenges in solving a highly non-linear problem. The RJ-MCMC method also presents a tantalizing possibility for extension to 2D and 3D Bayesian inversion of full waveform seismic data in the future, as it objectively tackles the problem of model selection (i.e., the number of layers or cells for parameterization), which could ease the computational burden of evaluating forward models with many parameters.

  7. Dynamic characterization of high damping viscoelastic materials from vibration test data

    NASA Astrophysics Data System (ADS)

    Martinez-Agirre, Manex; Elejabarrieta, María Jesús

    2011-08-01

    The numerical analysis and design of structural systems involving viscoelastic damping materials require knowledge of material properties and proper mathematical models. A new inverse method for the dynamic characterization of high damping and strong frequency-dependent viscoelastic materials from vibration test data measured by forced vibration tests with resonance is presented. Classical material parameter extraction methods are reviewed; their accuracy for characterizing high damping materials is discussed; and the bases of the new analysis method are detailed. The proposed inverse method minimizes the residue between the experimental and theoretical dynamic response at certain discrete frequencies selected by the user in order to identify the parameters of the material constitutive model. Thus, the material properties are identified in the whole bandwidth under study and not just at resonances. Moreover, the use of control frequencies makes the method insensitive to experimental noise and the efficiency is notably enhanced. Therefore, the number of tests required is drastically reduced and the overall process is carried out faster and more accurately. The effectiveness of the proposed method is demonstrated with the characterization of a CLD (constrained layer damping) cantilever beam. First, the elastic properties of the constraining layers are identified from the dynamic response of a metallic cantilever beam. Then, the viscoelastic properties of the core, represented by a four-parameter fractional derivative model, are identified from the dynamic response of a CLD cantilever beam.

  8. Inverse association between the frequency of nut consumption and obesity among Iranian population: Isfahan Healthy Heart Program.

    PubMed

    Mohammadifard, Noushin; Yazdekhasti, Narges; Stangl, Gabriele I; Sarrafzadegan, Nizal

    2015-09-01

    Recently, controversies have arisen concerning the association between nut intake and obesity. This study was performed to investigate the relationship between nut consumption and obesity among Iranian adults. In a cross-sectional survey, 9,660 randomly chosen adults aged ≥19 years were selected based on gender, age and their settlement distributions in three districts of central Iran in 2007. Nutritional behaviors including regular intake of walnuts, almonds, pistachios, hazelnuts and sunflower seed were assessed by validated 48-item-food-frequency questionnaire and a 24-h recall questionnaire. Using hierarchical logistic regression test, odds ratio (OR) 95% CI of obesity based on nut consumption was determined in an unadjusted and four adjusted models. The results showed a significant association between high nut consumption and lower prevalence of overweight or general obesity as well as abdominal obesity in women (p = 0.01 and p = 0.047, respectively), but not men. The frequency of nut consumption was associated with lower risk of overweight or general obesity [OR (95% CI) 0.57 (0.38-0.86)] and abdominal obesity [OR (95% CI) 0.51 (0.28-0.95)] only in women. After adjusting for gender, age and other potential confounders, the strength of the associations was blunted, but they were still significant. Frequent nuts and seeds consumption, particularly ≥1 time/day, had an inverse association with all classes of obesity among women.

  9. Estimation of Soil Moisture Under Vegetation Cover at Multiple Frequencies

    NASA Astrophysics Data System (ADS)

    Jadghuber, Thomas; Hajnsek, Irena; Weiß, Thomas; Papathanassiou, Konstantinos P.

    2015-04-01

    Soil moisture under vegetation cover was estimated by a polarimetric, iterative, generalized, hybrid decomposition and inversion approach at multiple frequencies (X-, C- and L-band). Therefore the algorithm, originally designed for longer wavelength (L-band), was adapted to deal with the short wavelength scattering scenarios of X- and C-band. The Integral Equation Method (IEM) was incorporated together with a pedo-transfer function of Dobson et al. to account for the peculiarities of short wavelength scattering at X- and C-band. DLR's F-SAR system acquired fully polarimetric SAR data in X-, C- and L-band over the Wallerfing test site in Lower Bavaria, Germany in 2014. Simultaneously, soil and vegetation measurements were conducted on different agricultural test fields. The results indicate a spatially continuous inversion of soil moisture in all three frequencies (inversion rates >92%), mainly due to the careful adaption of the vegetation volume removal including a physical constraining of the decomposition algorithm. However, for X- and C-band the inversion results reveal moisture pattern inconsistencies and in some cases an incorrectly high inversion of soil moisture at X-band. The validation with in situ measurements states a stable performance of 2.1- 7.6vol.% at L-band for the entire growing period. At C- and X-band a reliable performance of 3.7-13.4vol.% in RMSE can only be achieved after distinct filtering (X- band) leading to a loss of almost 60% in spatial inversion rate. Hence, a robust inversion for soil moisture estimation under vegetation cover can only be conducted at L-band due to a constant availability of the soil signal in contrast to higher frequencies (X- and C-band).

  10. Leptin levels in patients with systemic lupus erythematosus inversely correlate with regulatory T cell frequency.

    PubMed

    Wang, X; Qiao, Y; Yang, L; Song, S; Han, Y; Tian, Y; Ding, M; Jin, H; Shao, F; Liu, A

    2017-11-01

    Leptin levels are increased in patients with systemic lupus erythematosus (SLE) but little is known on how this correlates with several disease characteristics including the frequency of regulatory T cells (Tregs). Here we compared serum leptin levels with frequency of circulating Tregs in 47 lupus patients vs. 25 healthy matched controls. Correlations with lupus disease activity were also analyzed, as well as Treg proliferation potential. It was found that leptin was remarkably increased in SLE patients as compared to controls, particularly in SLE patients with moderate and severe active SLE, and the increase correlated with disease activity. Importantly, increased leptin in lupus patients inversely correlated with the frequency of Tregs but not in controls, and leptin neutralization resulted in the expansion of Tregs ex vivo. Thus, hyperleptinemia in lupus patients correlates directly with disease activity and inversely with Treg frequency. The finding that leptin inhibition expands Tregs in SLE suggests possible inhibition of this molecule for an enhanced Treg function in the disease.

  11. In-Plane Structure of Underpotentially Deposited Copper on Gold (111) Determined by Surface EXAFS (Extended X-Ray Absorption Fine Structure).

    DTIC Science & Technology

    1988-01-28

    EXAFS is the inverse transform of the two peaks in the RSF using a filtering a12 function to isolate the range between I and 4A. Both the frequency...backscattering of different neighbors. This inverse transform contains only one frequency and its envelope of intensity is the backscattering amplitude function...and the inverse transform of the RSF using a fourier filter between 1 and 4A (Solid line). Insert: Radial Structure Function (RSF) analyzed between

  12. ECG denoising with adaptive bionic wavelet transform.

    PubMed

    Sayadi, Omid; Shamsollahi, Mohammad Bagher

    2006-01-01

    In this paper a new ECG denoising scheme is proposed using a novel adaptive wavelet transform, named bionic wavelet transform (BWT), which had been first developed based on a model of the active auditory system. There has been some outstanding features with the BWT such as nonlinearity, high sensitivity and frequency selectivity, concentrated energy distribution and its ability to reconstruct signal via inverse transform but the most distinguishing characteristic of BWT is that its resolution in the time-frequency domain can be adaptively adjusted not only by the signal frequency but also by the signal instantaneous amplitude and its first-order differential. Besides by optimizing the BWT parameters parallel to modifying a new threshold value, one can handle ECG denoising with results comparing to those of wavelet transform (WT). Preliminary tests of BWT application to ECG denoising were constructed on the signals of MIT-BIH database which showed high performance of noise reduction.

  13. On using surface-source downhole-receiver logging to determine seismic slownesses

    USGS Publications Warehouse

    Boore, D.M.; Thompson, E.M.

    2007-01-01

    We present a method to solve for slowness models from surface-source downhole-receiver seismic travel-times. The method estimates the slownesses in a single inversion of the travel-times from all receiver depths and accounts for refractions at layer boundaries. The number and location of layer interfaces in the model can be selected based on lithologic changes or linear trends in the travel-time data. The interfaces based on linear trends in the data can be picked manually or by an automated algorithm. We illustrate the method with example sites for which geologic descriptions of the subsurface materials and independent slowness measurements are available. At each site we present slowness models that result from different interpretations of the data. The examples were carefully selected to address the reliability of interface-selection and the ability of the inversion to identify thin layers, large slowness contrasts, and slowness gradients. Additionally, we compare the models in terms of ground-motion amplification. These plots illustrate the sensitivity of site amplifications to the uncertainties in the slowness model. We show that one-dimensional site amplifications are insensitive to thin layers in the slowness models; although slowness is variable over short ranges of depth, this variability has little affect on ground-motion amplification at frequencies up to 5 Hz.

  14. Inverse transport calculations in optical imaging with subspace optimization algorithms

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ding, Tian, E-mail: tding@math.utexas.edu; Ren, Kui, E-mail: ren@math.utexas.edu

    2014-09-15

    Inverse boundary value problems for the radiative transport equation play an important role in optics-based medical imaging techniques such as diffuse optical tomography (DOT) and fluorescence optical tomography (FOT). Despite the rapid progress in the mathematical theory and numerical computation of these inverse problems in recent years, developing robust and efficient reconstruction algorithms remains a challenging task and an active research topic. We propose here a robust reconstruction method that is based on subspace minimization techniques. The method splits the unknown transport solution (or a functional of it) into low-frequency and high-frequency components, and uses singular value decomposition to analyticallymore » recover part of low-frequency information. Minimization is then applied to recover part of the high-frequency components of the unknowns. We present some numerical simulations with synthetic data to demonstrate the performance of the proposed algorithm.« less

  15. Improved mutagen testing systems in mice. Final report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Roderick, T.H.

    Our laboratory was the first to induce and ascertain a mammalian chromosomal inversion; we did this by searching for a high frequency of first meiotic anaphase bridges in testes of males whose fathers received post-spermatogonial radiation or mutagenesis from chromosomal breaking chemical mutagens. One test in was examined in each mouse, and those showing a high frequency were then mated to determine if the high frequency were passed on as a dominant and whether linkage analysis suggested the presence of an inversion. A very high incidence (exceeding 20% bridges in first meiotic anaphase bridges) was found in about 1 inmore » 150 males examined and this frequency was generally found to be passed on to the offspring an predicted. Later cytological banding techniques were developed elsewhere and we used them to show visually the inverted orders of the inverted chromosomal segments. Since that time we have induced inversions covering most of the mouse genome.« less

  16. Improved mutagen testing systems in mice

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Roderick, T.H.

    Our laboratory was the first to induce and ascertain a mammalian chromosomal inversion; we did this by searching for a high frequency of first meiotic anaphase bridges in testes of males whose fathers received post-spermatogonial radiation or mutagenesis from chromosomal breaking chemical mutagens. One test in was examined in each mouse, and those showing a high frequency were then mated to determine if the high frequency were passed on as a dominant and whether linkage analysis suggested the presence of an inversion. A very high incidence (exceeding 20% bridges in first meiotic anaphase bridges) was found in about 1 inmore » 150 males examined and this frequency was generally found to be passed on to the offspring an predicted. Later cytological banding techniques were developed elsewhere and we used them to show visually the inverted orders of the inverted chromosomal segments. Since that time we have induced inversions covering most of the mouse genome.« less

  17. Recombination rate predicts inversion size in Diptera.

    PubMed Central

    Cáceres, M; Barbadilla, A; Ruiz, A

    1999-01-01

    Most species of the Drosophila genus and other Diptera are polymorphic for paracentric inversions. A common observation is that successful inversions are of intermediate size. We test here the hypothesis that the selected property is the recombination length of inversions, not their physical length. If so, physical length of successful inversions should be negatively correlated with recombination rate across species. This prediction was tested by a comprehensive statistical analysis of inversion size and recombination map length in 12 Diptera species for which appropriate data are available. We found that (1) there is a wide variation in recombination map length among species; (2) physical length of successful inversions varies greatly among species and is inversely correlated with the species recombination map length; and (3) neither the among-species variation in inversion length nor the correlation are observed in unsuccessful inversions. The clear differences between successful and unsuccessful inversions point to natural selection as the most likely explanation for our results. Presumably the selective advantage of an inversion increases with its length, but so does its detrimental effect on fertility due to double crossovers. Our analysis provides the strongest and most extensive evidence in favor of the notion that the adaptive value of inversions stems from their effect on recombination. PMID:10471710

  18. Frequency-domain elastic full waveform inversion using encoded simultaneous sources

    NASA Astrophysics Data System (ADS)

    Jeong, W.; Son, W.; Pyun, S.; Min, D.

    2011-12-01

    Currently, numerous studies have endeavored to develop robust full waveform inversion and migration algorithms. These processes require enormous computational costs, because of the number of sources in the survey. To avoid this problem, the phase encoding technique for prestack migration was proposed by Romero (2000) and Krebs et al. (2009) proposed the encoded simultaneous-source inversion technique in the time domain. On the other hand, Ben-Hadj-Ali et al. (2011) demonstrated the robustness of the frequency-domain full waveform inversion with simultaneous sources for noisy data changing the source assembling. Although several studies on simultaneous-source inversion tried to estimate P- wave velocity based on the acoustic wave equation, seismic migration and waveform inversion based on the elastic wave equations are required to obtain more reliable subsurface information. In this study, we propose a 2-D frequency-domain elastic full waveform inversion technique using phase encoding methods. In our algorithm, the random phase encoding method is employed to calculate the gradients of the elastic parameters, source signature estimation and the diagonal entries of approximate Hessian matrix. The crosstalk for the estimated source signature and the diagonal entries of approximate Hessian matrix are suppressed with iteration as for the gradients. Our 2-D frequency-domain elastic waveform inversion algorithm is composed using the back-propagation technique and the conjugate-gradient method. Source signature is estimated using the full Newton method. We compare the simultaneous-source inversion with the conventional waveform inversion for synthetic data sets of the Marmousi-2 model. The inverted results obtained by simultaneous sources are comparable to those obtained by individual sources, and source signature is successfully estimated in simultaneous source technique. Comparing the inverted results using the pseudo Hessian matrix with previous inversion results provided by the approximate Hessian matrix, it is noted that the latter are better than the former for deeper parts of the model. This work was financially supported by the Brain Korea 21 project of Energy System Engineering, by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology (2010-0006155), by the Energy Efficiency & Resources of the Korea Institute of Energy Technology Evaluation and Planning (KETEP) grant funded by the Korea government Ministry of Knowledge Economy (No. 2010T100200133).

  19. Analysis of the load selection on the error of source characteristics identification for an engine exhaust system

    NASA Astrophysics Data System (ADS)

    Zheng, Sifa; Liu, Haitao; Dan, Jiabi; Lian, Xiaomin

    2015-05-01

    Linear time-invariant assumption for the determination of acoustic source characteristics, the source strength and the source impedance in the frequency domain has been proved reasonable in the design of an exhaust system. Different methods have been proposed to its identification and the multi-load method is widely used for its convenience by varying the load number and impedance. Theoretical error analysis has rarely been referred to and previous results have shown an overdetermined set of open pipes can reduce the identification error. This paper contributes a theoretical error analysis for the load selection. The relationships between the error in the identification of source characteristics and the load selection were analysed. A general linear time-invariant model was built based on the four-load method. To analyse the error of the source impedance, an error estimation function was proposed. The dispersion of the source pressure was obtained by an inverse calculation as an indicator to detect the accuracy of the results. It was found that for a certain load length, the load resistance at the frequency points of one-quarter wavelength of odd multiples results in peaks and in the maximum error for source impedance identification. Therefore, the load impedance of frequency range within the one-quarter wavelength of odd multiples should not be used for source impedance identification. If the selected loads have more similar resistance values (i.e., the same order of magnitude), the identification error of the source impedance could be effectively reduced.

  20. Image fusion method based on regional feature and improved bidimensional empirical mode decomposition

    NASA Astrophysics Data System (ADS)

    Qin, Xinqiang; Hu, Gang; Hu, Kai

    2018-01-01

    The decomposition of multiple source images using bidimensional empirical mode decomposition (BEMD) often produces mismatched bidimensional intrinsic mode functions, either by their number or their frequency, making image fusion difficult. A solution to this problem is proposed using a fixed number of iterations and a union operation in the sifting process. By combining the local regional features of the images, an image fusion method has been developed. First, the source images are decomposed using the proposed BEMD to produce the first intrinsic mode function (IMF) and residue component. Second, for the IMF component, a selection and weighted average strategy based on local area energy is used to obtain a high-frequency fusion component. Third, for the residue component, a selection and weighted average strategy based on local average gray difference is used to obtain a low-frequency fusion component. Finally, the fused image is obtained by applying the inverse BEMD transform. Experimental results show that the proposed algorithm provides superior performance over methods based on wavelet transform, line and column-based EMD, and complex empirical mode decomposition, both in terms of visual quality and objective evaluation criteria.

  1. Comparison of the convolution quadrature method and enhanced inverse FFT with application in elastodynamic boundary element method

    NASA Astrophysics Data System (ADS)

    Schanz, Martin; Ye, Wenjing; Xiao, Jinyou

    2016-04-01

    Transient problems can often be solved with transformation methods, where the inverse transformation is usually performed numerically. Here, the discrete Fourier transform in combination with the exponential window method is compared with the convolution quadrature method formulated as inverse transformation. Both are inverse Laplace transforms, which are formally identical but use different complex frequencies. A numerical study is performed, first with simple convolution integrals and, second, with a boundary element method (BEM) for elastodynamics. Essentially, when combined with the BEM, the discrete Fourier transform needs less frequency calculations, but finer mesh compared to the convolution quadrature method to obtain the same level of accuracy. If further fast methods like the fast multipole method are used to accelerate the boundary element method the convolution quadrature method is better, because the iterative solver needs much less iterations to converge. This is caused by the larger real part of the complex frequencies necessary for the calculation, which improves the conditions of system matrix.

  2. Broadband focusing ultrasonic transducers based on dimpled LiNbO3 plate with inversion layer.

    PubMed

    Chen, Jin; Dai, Ji-Yan; Zhang, Chao; Zhang, Zhitian; Feng, Guanping

    2012-12-01

    A high-frequency broadband focusing transducer based on dimpled LiNbO(3) inversion layer plate has been fabricated and characterized. A spherical surface with a curvature radius of 6 mm is formed on the half-thickness LiNbO(3) inversion layer plate of Y36° cut orientation. The domain structure in the cross section is observed after a hydrofluoric acid etching process. For transducer fabrication, conductive epoxy is used as the backing material and polymer is deposited on the front face as the matching layer. The center frequency, bandwidth, and insertion loss of the focused transducer are measured to be 72 MHz, 136%, and -32 dB, respectively. The focused transducer has been successfully used for rabbit eyeball imaging and a better imaging capability compared with the planar transducer has been demonstrated. These promising results prove that the dimpled LiNbO(3) inversion layer plate has great potential for fabrication of high-frequency broadband focusing ultrasonic transducers.

  3. A Modified Normalization Technique for Frequency-Domain Full Waveform Inversion

    NASA Astrophysics Data System (ADS)

    Hwang, J.; Jeong, G.; Min, D. J.; KIM, S.; Heo, J. Y.

    2016-12-01

    Full waveform inversion (FWI) is a technique to estimate subsurface material properties minimizing the misfit function built with residuals between field and modeled data. To achieve computational efficiency, FWI has been performed in the frequency domain by carrying out modeling in the frequency domain, whereas observed data (time-series data) are Fourier-transformed.One of the main drawbacks of seismic FWI is that it easily gets stuck in local minima because of lacking of low-frequency data. To compensate for this limitation, damped wavefields are used, as in the Laplace-domain waveform inversion. Using damped wavefield in FWI plays a role in generating low-frequency components and help recover long-wavelength structures. With these newly generated low-frequency components, we propose a modified frequency-normalization technique, which has an effect of boosting contribution of low-frequency components to model parameter update.In this study, we introduce the modified frequency-normalization technique which effectively amplifies low-frequency components of damped wavefields. Our method is demonstrated for synthetic data for the SEG/EAGE salt model. AcknowledgementsThis work was supported by the Korea Institute of Energy Technology Evaluation and Planning(KETEP) and the Ministry of Trade, Industry & Energy(MOTIE) of the Republic of Korea (No. 20168510030830) and by the Dual Use Technology Program, granted financial resource from the Ministry of Trade, Industry & Energy, Republic of Korea.

  4. Microstrip patch antenna for simultaneous strain and temperature sensing

    NASA Astrophysics Data System (ADS)

    Mbanya Tchafa, F.; Huang, H.

    2018-06-01

    A patch antenna, consisting of a radiation patch, a dielectric substrate, and a ground plane, resonates at distinct fundamental frequencies that depend on the substrate dielectric constant and the dimensions of the radiation patch. Since these parameters change with the applied strain and temperature, this study investigates simultaneous strain and temperature sensing using a single antenna that has two fundamental resonant frequencies. The theoretical relationship between the antenna resonant frequency shifts, the temperature, and the applied strain was first established to guide the selection of the dielectric substrate, based on which an antenna sensor with a rectangular radiation patch was designed and fabricated. A tensile test specimen instrumented with the antenna sensor was subjected to thermo-mechanical tests. Experiment results validated the theoretical predictions that the normalized antenna resonant frequency shifts are linearly proportional to the applied strain and temperature changes. An inverse method was developed to determine the strain and temperature changes from the normalized antenna resonant frequency shifts, yielding measurement uncertainty of 0.4 °C and 17.22 μ \\varepsilon for temperature and strain measurement, respectively.

  5. Moment-tensor inversion for offshore earthquakes east of Taiwan and their implications to regional collision

    NASA Astrophysics Data System (ADS)

    Kao, Honn; Jian, Pei-Ru; Ma, Kuo-Fong; Huang, Bor-Shouh; Liu, Chun-Chi

    Reliable determination of source parameters for offshore earthquakes east of Taiwan with mb<5.5 was a difficult task because of the poor azimuthal coverage by local network and the lack of signals at teleseismic distances. We take advantage of the recently established “Broadband Array in Taiwan for Seismology” (BATS) to invert seismic moment tensors for 7 such events occurred in 1996. To cope with different patterns of background noise and unknown structural details, we utilize variable frequency bands in the inversion and adapt a two-step procedure to select best velocity models for individual epicenter-station paths. Our results are consistent with the overall patterns of regional collision and indicate that the resulting compressive stress has caused significant intraplate deformation within the Philippine Sea plate. Simulation of the region's geological evolution and orogenic processes should take this factor into account and allow the Philippine Sea plate to deform internally.

  6. A robust spatial filtering technique for multisource localization and geoacoustic inversion.

    PubMed

    Stotts, S A

    2005-07-01

    Geoacoustic inversion and source localization using beamformed data from a ship of opportunity has been demonstrated with a bottom-mounted array. An alternative approach, which lies within a class referred to as spatial filtering, transforms element level data into beam data, applies a bearing filter, and transforms back to element level data prior to performing inversions. Automation of this filtering approach is facilitated for broadband applications by restricting the inverse transform to the degrees of freedom of the array, i.e., the effective number of elements, for frequencies near or below the design frequency. A procedure is described for nonuniformly spaced elements that guarantees filter stability well above the design frequency. Monitoring energy conservation with respect to filter output confirms filter stability. Filter performance with both uniformly spaced and nonuniformly spaced array elements is discussed. Vertical (range and depth) and horizontal (range and bearing) ambiguity surfaces are constructed to examine filter performance. Examples that demonstrate this filtering technique with both synthetic data and real data are presented along with comparisons to inversion results using beamformed data. Examinations of cost functions calculated within a simulated annealing algorithm reveal the efficacy of the approach.

  7. Resolution of VTI anisotropy with elastic full-waveform inversion: theory and basic numerical examples

    NASA Astrophysics Data System (ADS)

    Podgornova, O.; Leaney, S.; Liang, L.

    2018-07-01

    Extracting medium properties from seismic data faces some limitations due to the finite frequency content of the data and restricted spatial positions of the sources and receivers. Some distributions of the medium properties make low impact on the data (including none). If these properties are used as the inversion parameters, then the inverse problem becomes overparametrized, leading to ambiguous results. We present an analysis of multiparameter resolution for the linearized inverse problem in the framework of elastic full-waveform inversion. We show that the spatial and multiparameter sensitivities are intertwined and non-sensitive properties are spatial distributions of some non-trivial combinations of the conventional elastic parameters. The analysis accounts for the Hessian information and frequency content of the data; it is semi-analytical (in some scenarios analytical), easy to interpret and enhances results of the widely used radiation pattern analysis. Single-type scattering is shown to have limited sensitivity, even for full-aperture data. Finite-frequency data lose multiparameter sensitivity at smooth and fine spatial scales. Also, we establish ways to quantify a spatial-multiparameter coupling and demonstrate that the theoretical predictions agree well with the numerical results.

  8. Adaptive eigenspace method for inverse scattering problems in the frequency domain

    NASA Astrophysics Data System (ADS)

    Grote, Marcus J.; Kray, Marie; Nahum, Uri

    2017-02-01

    A nonlinear optimization method is proposed for the solution of inverse scattering problems in the frequency domain, when the scattered field is governed by the Helmholtz equation. The time-harmonic inverse medium problem is formulated as a PDE-constrained optimization problem and solved by an inexact truncated Newton-type iteration. Instead of a grid-based discrete representation, the unknown wave speed is projected to a particular finite-dimensional basis of eigenfunctions, which is iteratively adapted during the optimization. Truncating the adaptive eigenspace (AE) basis at a (small and slowly increasing) finite number of eigenfunctions effectively introduces regularization into the inversion and thus avoids the need for standard Tikhonov-type regularization. Both analytical and numerical evidence underpins the accuracy of the AE representation. Numerical experiments demonstrate the efficiency and robustness to missing or noisy data of the resulting adaptive eigenspace inversion method.

  9. Transcription of detoxification genes following permethrin selection in the mosquito Aedes aegypti

    PubMed Central

    Saavedra-Rodriguez, Karla; Suarez, Adriana Flores; Salas, Ildefonso Fernandez; Strode, Clare; Ranson, Hilary; Hemingway, Janet; Black, William C.

    2011-01-01

    Changes in gene expression before, during and after five generations of permethrin laboratory selection were monitored in six strains of Aedes aegypti: five F2 – F3 collections from the Yucatán Peninsula of México and one F2 from Iquitos, Perú. Three biological replicate lines were generated for each strain. The response to selection was measured as changes in the lethal and knockdown permethrin concentrations (LC50, KC50) and in the frequency of the Ile1,016 substitution in the voltage gated sodium channel (para) gene. Changes in expression of 290 metabolic detoxification genes were measured using the “Aedes Detox” microarray. Selection simultaneously increased the LC50, KC50 and Ile1,016 frequency. There was an inverse relationship between Ile1,016 frequency and the numbers of differentially transcribed genes. The Iquitos strain lacked the Ile1,016 allele and 51 genes were differentially transcribed following selection as compared to 10–18 genes in the Mexican strains. Very few of the same genes were differentially transcribed among field strains but ten cytochrome P450 genes were upregulated in more than one strain. Laboratory adaptation to permethrin in Ae. aegypti is genetically complex and largely conditioned by geographic origin and preexisting target site insensitivity in the para gene. The lack of uniformity in the genes that responded to artificial selection as well as differences in the direction of their responses challenges the assumption that one or a few genes control permethrin metabolic resistance. Attempts to identify one or a few metabolic genes that are predictably associated with permethrin adaptation may be futile. PMID:22032702

  10. Interference stabilization of atoms in a strong laser field for obtaining inversion and lasing in the visible and VUV frequency ranges

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bogatskaya, A. V., E-mail: annabogatskaya@gmail.com; Volkova, E. A.; Popov, A. M.

    2016-09-15

    The interference stabilization of Rydberg atoms in strong laser fields is proposed for producing a plasma channel with the inverse population. Inversion between a group of Rydberg levels and low-lying excited levels and the ground state permits amplification and lasing in the IR, visible, and VUV frequency ranges. The lasing and light amplification processes in the plasma channel are analyzed using rate equations and the efficiency of this method is compared with that in the usual method for high harmonic generation during rescattering of electrons by a parent ion.

  11. Two radiation-induced chromosomal inversions in mice (Mus musculus).

    PubMed

    Roderick, T H; Hawes, N L

    1970-10-01

    Whole-body x-irradiation of male mice has produced presumptive paracentric inversions in 15 animals, as evidenced by high frequencies of first meiotic anaphase bridges. Two of the highest frequencies observed have been propagated through several generations and found to behave as dominant genes. Acentric fragments were observed associated with about 10% of the bridges. The first inversion, in linkage group XIII, has been designated In(13)1Rk, and the second, in linkage group XVII, In(17)2Rk. For In(13)1Rk, recombination was reduced between loci inside and outside the inverted segment.

  12. The Inverse Optimal Control Problem for a Three-Loop Missile Autopilot

    NASA Astrophysics Data System (ADS)

    Hwang, Donghyeok; Tahk, Min-Jea

    2018-04-01

    The performance characteristics of the autopilot must have a fast response to intercept a maneuvering target and reasonable robustness for system stability under the effect of un-modeled dynamics and noise. By the conventional approach, the three-loop autopilot design is handled by time constant, damping factor and open-loop crossover frequency to achieve the desired performance requirements. Note that the general optimal theory can be also used to obtain the same gain as obtained from the conventional approach. The key idea of using optimal control technique for feedback gain design revolves around appropriate selection and interpretation of the performance index for which the control is optimal. This paper derives an explicit expression, which relates the weight parameters appearing in the quadratic performance index to the design parameters such as open-loop crossover frequency, phase margin, damping factor, or time constant, etc. Since all set of selection of design parameters do not guarantee existence of optimal control law, explicit inequalities, which are named the optimality criteria for the three-loop autopilot (OC3L), are derived to find out all set of design parameters for which the control law is optimal. Finally, based on OC3L, an efficient gain selection procedure is developed, where time constant is set to design objective and open-loop crossover frequency and phase margin as design constraints. The effectiveness of the proposed technique is illustrated through numerical simulations.

  13. Simulation of Ground Winds Time Series for the NASA Crew Launch Vehicle (CLV)

    NASA Technical Reports Server (NTRS)

    Adelfang, Stanley I.

    2008-01-01

    Simulation of wind time series based on power spectrum density (PSD) and spectral coherence models for ground wind turbulence is described. The wind models, originally developed for the Shuttle program, are based on wind measurements at the NASA 150-m meteorological tower at Cape Canaveral, FL. The current application is for the design and/or protection of the CLV from wind effects during on-pad exposure during periods from as long as days prior to launch, to seconds or minutes just prior to launch and seconds after launch. The evaluation of vehicle response to wind will influence the design and operation of constraint systems for support of the on-pad vehicle. Longitudinal and lateral wind component time series are simulated at critical vehicle locations. The PSD model for wind turbulence is a function of mean wind speed, elevation and temporal frequency. Integration of the PSD equation over a selected frequency range yields the variance of the time series to be simulated. The square root of the PSD defines a low-pass filter that is applied to adjust the components of the Fast Fourier Transform (FFT) of Gaussian white noise. The first simulated time series near the top of the launch vehicle is the inverse transform of the adjusted FFT. Simulation of the wind component time series at the nearest adjacent location (and all other succeeding next nearest locations) is based on a model for the coherence between winds at two locations as a function of frequency and separation distance, where the adjacent locations are separated vertically and/or horizontally. The coherence function is used to calculate a coherence weighted FFT of the wind at the next nearest location, given the FFT of the simulated time series at the previous location and the essentially incoherent FFT of the wind at the selected location derived a priori from the PSD model. The simulated time series at each adjacent location is the inverse Fourier transform of the coherence weighted FFT. For a selected design case, the equations, the process and the simulated time series at multiple vehicle stations are presented.

  14. Magnetotelluric Investigation in the Jiyang Depression and its Adjacent Areas

    NASA Astrophysics Data System (ADS)

    Zhang, L.; Hao, T.; Duan, Q.

    2008-12-01

    The Jiyang Depression is a secondary tectonic unit of the Bohai Bay Basin, and is a Mesozoic-Cenozoic continental-facie depositional depression. The Jiyang Depression consists of the Dongying, Zanhua, Chezhen, and Huimin sags, and the Yihezhuang, Chenjiazhuang, Qingcheng, Binxian, Guangrao, Shouguang, and heaves. In order to delineate shallow and deep structures of the depression, we conduct a magnetotelluric (MT) investigation in the Jiyang Depression and its adjacent areas. We use a remote reference setup to reduce noise disturbance, when several magnetotelluric sounding stations are measuring synchronously at different sites. The acquired MT data are to be processed and interpreted. We execute time series processing with the remote reference technique. The surveyed area is seriously interfered by noise. To improve quality of the data, we perform noise identification and manual selection of the time series segments. Identification of polarization modes is an important task for MT data qualitative interpretation. We apply for a PCA (principal component analysis) based method to automatically identify apparent polarized resistivity curves of TE and TM modes. The method recognizes the distortion and major variation of TE and TM curves and distinguishes the two kinds of curves with principal component analysis. From the apparent resistivity-frequency profile result, we can see that the Chenning Uplift and the Chenjiazhuang Heave reveal a 3-layered structure of medium-low-high, from the shallow to the deep. The structure is especially distinct for the Chenning Uplift, where there is a laterally steady-spreading high- resistivity zone corresponding to the frequency band lower than 1 Hz. The Dongying Sag is characteristic of high-low-medium from the shallow to the deep, and has a low-resistivity anomaly zone with obvious and wide lateral extending in the medium frequency band, which reflects that the deposition thickness of the basin is relatively big. The Guangrao Heave and the Shouguang Heave are of a medium-low-high structure from the shallow to the deep. From the impedance phase-frequency profile image, it can be seen that electrical anomalies appear as a large variation in the cross direction, which indicates the complicated features of the research area. We use the 2-D Mackie inversion method to obtain underground electrical distribution of the surveyed area. We select the TE, TM, and joint TE-TM curves to realize inversion processing. The inversion result of the TM mode is used for further interpretation because the fitting conditions of the TM mode is better and the corresponding inversion result coincides well with geologic data. From the inversion result, we can see that the Chenning Uplift and the Changwei Depression to the south of the Guangrao Heave are of high-resistivity. The low-resisitivity range of the Dongying Sag shows that the bottom surface of the basin is about 8-10 km deep, which almost coincides with the published data. Generally speaking, the basement structures of four segments, the Chengning Uplift, the Chenzhen-Chenjiazhuang Heave, the Dongying Sag, and the Changwei Depression, differs greatly, and shows an overall feature that the uplift areas have root while the burial hills in the depression areas are with no root. It may indicate a prospective for pre-Cenozoic oil and gas resources.

  15. Fat suppression with short inversion time inversion-recovery and chemical-shift selective saturation: a dual STIR-CHESS combination prepulse for turbo spin echo pulse sequences.

    PubMed

    Tanabe, Koji; Nishikawa, Keiichi; Sano, Tsukasa; Sakai, Osamu; Jara, Hernán

    2010-05-01

    To test a newly developed fat suppression magnetic resonance imaging (MRI) prepulse that synergistically uses the principles of fat suppression via inversion recovery (STIR) and spectral fat saturation (CHESS), relative to pure CHESS and STIR. This new technique is termed dual fat suppression (Dual-FS). To determine if Dual-FS could be chemically specific for fat, the phantom consisted of the fat-mimicking NiCl(2) aqueous solution, porcine fat, porcine muscle, and water was imaged with the three fat-suppression techniques. For Dual-FS and STIR, several inversion times were used. Signal intensities of each image obtained with each technique were compared. To determine if Dual-FS could be robust to magnetic field inhomogeneities, the phantom consisting of different NiCl(2) aqueous solutions, porcine fat, porcine muscle, and water was imaged with Dual-FS and CHESS at the several off-resonance frequencies. To compare fat suppression efficiency in vivo, 10 volunteer subjects were also imaged with the three fat-suppression techniques. Dual-FS could suppress fat sufficiently within the inversion time of 110-140 msec, thus enabling differentiation between fat and fat-mimicking aqueous structures. Dual-FS was as robust to magnetic field inhomogeneities as STIR and less vulnerable than CHESS. The same results for fat suppression were obtained in volunteers. The Dual-FS-STIR-CHESS is an alternative and promising fat suppression technique for turbo spin echo MRI. Copyright 2010 Wiley-Liss, Inc.

  16. Linkage Disequilibrium and Inversion-Typing of the Drosophila melanogaster Genome Reference Panel

    PubMed Central

    Houle, David; Márquez, Eladio J.

    2015-01-01

    We calculated the linkage disequilibrium between all pairs of variants in the Drosophila Genome Reference Panel with minor allele count ≥5. We used r2 ≥ 0.5 as the cutoff for a highly correlated SNP. We make available the list of all highly correlated SNPs for use in association studies. Seventy-six percent of variant SNPs are highly correlated with at least one other SNP, and the mean number of highly correlated SNPs per variant over the whole genome is 83.9. Disequilibrium between distant SNPs is also common when minor allele frequency (MAF) is low: 37% of SNPs with MAF < 0.1 are highly correlated with SNPs more than 100 kb distant. Although SNPs within regions with polymorphic inversions are highly correlated with somewhat larger numbers of SNPs, and these correlated SNPs are on average farther away, the probability that a SNP in such regions is highly correlated with at least one other SNP is very similar to SNPs outside inversions. Previous karyotyping of the DGRP lines has been inconsistent, and we used LD and genotype to investigate these discrepancies. When previous studies agreed on inversion karyotype, our analysis was almost perfectly concordant with those assignments. In discordant cases, and for inversion heterozygotes, our results suggest errors in two previous analyses or discordance between genotype and karyotype. Heterozygosities of chromosome arms are, in many cases, surprisingly highly correlated, suggesting strong epsistatic selection during the inbreeding and maintenance of the DGRP lines. PMID:26068573

  17. Linkage Disequilibrium and Inversion-Typing of the Drosophila melanogaster Genome Reference Panel.

    PubMed

    Houle, David; Márquez, Eladio J

    2015-06-10

    We calculated the linkage disequilibrium between all pairs of variants in the Drosophila Genome Reference Panel with minor allele count ≥5. We used r(2) ≥ 0.5 as the cutoff for a highly correlated SNP. We make available the list of all highly correlated SNPs for use in association studies. Seventy-six percent of variant SNPs are highly correlated with at least one other SNP, and the mean number of highly correlated SNPs per variant over the whole genome is 83.9. Disequilibrium between distant SNPs is also common when minor allele frequency (MAF) is low: 37% of SNPs with MAF < 0.1 are highly correlated with SNPs more than 100 kb distant. Although SNPs within regions with polymorphic inversions are highly correlated with somewhat larger numbers of SNPs, and these correlated SNPs are on average farther away, the probability that a SNP in such regions is highly correlated with at least one other SNP is very similar to SNPs outside inversions. Previous karyotyping of the DGRP lines has been inconsistent, and we used LD and genotype to investigate these discrepancies. When previous studies agreed on inversion karyotype, our analysis was almost perfectly concordant with those assignments. In discordant cases, and for inversion heterozygotes, our results suggest errors in two previous analyses or discordance between genotype and karyotype. Heterozygosities of chromosome arms are, in many cases, surprisingly highly correlated, suggesting strong epsistatic selection during the inbreeding and maintenance of the DGRP lines. Copyright © 2015 Houle and Márquez.

  18. Study on geophone coupling and attenuating compensatory of low-depression velocity layer in desert area

    USGS Publications Warehouse

    Shi, Z.; Tian, G.; Dong, S.; Xia, J.; He, H.; ,

    2004-01-01

    In a desert area, it is difficult to couple geophones with dry sands. A low and depression velocity layer can seriously attenuate high frequency components of seismic data. Therefore, resolution and signal-to-noise (S/N) ratio of seismic data deteriorate. To enhance resolution and S/N ratio of seismic data, we designed a coupling compensatory inverse filter by using the single trace seismic data from Seismic Wave Detect System (SWDS) and common receivers on equal conditions. We designed an attenuating compensatory inverse filter by using seismic data from a microseismogram log. At last, in order to convert a shot gather from common receivers to a shot gather from SWDS, we applied the coupling compensatory inverse filter to the shot gather from common receivers. And then we applied the attenuating compensatory inverse filter to the coupling stacked seismic data to increase its resolution and S/N ratio. The results show that the resolution of seismic data from common receivers after processing by using the coupling compensatory inverse filter is nearly comparable with that of data from SWDS. It is also found that the resolution and S/N ratio have been enhanced after the use of attenuating compensatory inverse filter. From the results, we can conclude that the filters can compensate high frequencies of seismic data. Moreover, the low frequency changed nearly.

  19. Bispectral Inversion: The Construction of a Time Series from Its Bispectrum

    DTIC Science & Technology

    1988-04-13

    take the inverse transform . Since the goal is to compute a time series given its bispectrum, it would also be nice to stay entirely in the frequency...domain and be able to go directly from the bispectrum to the Fourier transform of the time series without the need to inverse transform continuous...the picture. The approximations arise from representing the bicovariance, which is the inverse transform of a continuous function, by the inverse disrte

  20. Stabilization of a system with saturating, non-monotone hysteresis and frequency dependent power losses by a PD controller

    NASA Astrophysics Data System (ADS)

    Ekanayake, D. B.; Iyer, R. V.

    2015-02-01

    We prove the closed loop stability of a PD controller for certain systems with saturating, non-monotone hysteresis and frequency dependent power losses. Most controllers use inverse compensators to cancel out actuator hysteresis nonlinearity. We show that we can achieve stability of the closed-loop system without an explicit inverse computation (using least squares minimization or otherwise).

  1. 76 FR 14616 - Approval and Promulgation of Implementation Plans; State of California; Interstate Transport of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-17

    ... during the winter time, when frequent and persistent temperature inversions occur, were specifically... winds and strong temperature inversions. These meteorological conditions may trap emissions within the... show a very high frequency of surface temperature inversions in the winter. Due to the meteorology...

  2. Comparison of weighting techniques for acoustic full waveform inversion

    NASA Astrophysics Data System (ADS)

    Jeong, Gangwon; Hwang, Jongha; Min, Dong-Joo

    2017-12-01

    To reconstruct long-wavelength structures in full waveform inversion (FWI), the wavefield-damping and weighting techniques have been used to synthesize and emphasize low-frequency data components in frequency-domain FWI. However, these methods have some weak points. The application of wavefield-damping method on filtered data fails to synthesize reliable low-frequency data; the optimization formula obtained introducing the weighting technique is not theoretically complete, because it is not directly derived from the objective function. In this study, we address these weak points and present how to overcome them. We demonstrate that the source estimation in FWI using damped wavefields fails when the data used in the FWI process does not satisfy the causality condition. This phenomenon occurs when a non-causal filter is applied to data. We overcome this limitation by designing a causal filter. Also we modify the conventional weighting technique so that its optimization formula is directly derived from the objective function, retaining its original characteristic of emphasizing the low-frequency data components. Numerical results show that the newly designed causal filter enables to recover long-wavelength structures using low-frequency data components synthesized by damping wavefields in frequency-domain FWI, and the proposed weighting technique enhances the inversion results.

  3. Utilization of high-frequency Rayleigh waves in near-surface geophysics

    USGS Publications Warehouse

    Xia, J.; Miller, R.D.; Park, C.B.; Ivanov, J.; Tian, G.; Chen, C.

    2004-01-01

    Shear-wave velocities can be derived from inverting the dispersive phase velocity of the surface. The multichannel analysis of surface waves (MASW) is one technique for inverting high-frequency Rayleigh waves. The process includes acquisition of high-frequency broad-band Rayleigh waves, efficient and accurate algorithms designed to extract Rayleigh-wave dispersion curves from Rayleigh waves, and stable and efficient inversion algorithms to obtain near-surface S-wave velocity profiles. MASW estimates S-wave velocity from multichannel vertical compoent data and consists of data acquisition, dispersion-curve picking, and inversion.

  4. Search for inversion splitting in the 3ν2 band of phosphine

    NASA Astrophysics Data System (ADS)

    Okuda, Shoko; Sasada, Hiroyuki

    2018-04-01

    Sub-Doppler resolution spectroscopy of the 3ν2 band of phosphine has been carried out using a difference-frequency-generation source referenced to an optical frequency comb and a cavity-enhanced absorption cell. Three Q-branch transitions are recorded with a linewidth of 150 kHz, but no inversion splitting is observed even though it was predicted 300 kHz in Journal of Chemical Physics, vol. 145, art. No. 091102 (2016). Transition frequencies of six Q-branch transitions have been determined with an uncertainty of 6-16 kHz.

  5. Characterizing Arctic mixed-phase cloud structure and its relationship with humidity and temperature inversion using ARM NSA observations

    NASA Astrophysics Data System (ADS)

    Qiu, Shaoyue; Dong, Xiquan; Xi, Baike; Li, J.-L. F.

    2015-08-01

    In this study, the characteristics of the Arctic mixed-phase cloud (AMC) have been investigated using data collected at the Atmospheric Radiation Measurement North Slope Alaska site from October 2006 to September 2009. AMC has an annual occurrence frequency of 42.3%, which includes 18.7% of single-layered AMCs and 23.6% for multiple layers. Two cloud base heights (CBHs) are defined from ceilometer and micropulse lidar (MPL) measurements. For single-layered AMC, the ceilometer-derived CBH represents the base of the liquid-dominant layer near the cloud top, while MPL-derived CBH represents base of the lower ice-dominant layer. The annual mean CBHs from ceilometer and MPL measurements are 1.0 km and 0.6 km, respectively, with the largest difference ( 1.0 km) occurring from December to March and the smallest difference in September. The humidity inversion occurrence decreases with increasing humidity inversion intensity (stronger in summer than in winter). During the winter months, AMC occurrences increase from 15% to 35% when the inversion intensity increases from 0.1 to 0.9 g/kg. On the contrary, despite a higher frequency of strong humidity inversion in summer, AMC occurrences are nearly invariant for different inversion intensities. On average, humidity and temperature inversion frequencies of occurrence above an AMC are 5 and 8 times, respectively, as high as those below an AMC. The strong inversion occurrences for both humidity and temperature above an AMC provide the moisture sources from above for the formation and maintenance of AMCs. This result helps to reconcile the persistency of AMCs even when the Arctic surface is covered by snow and ice.

  6. Joint Inversion of 1-Hz GPS Data and Strong Motion Records for the Rupture Process of the 2008 Iwate-Miyagi Nairiku Earthquake: Objectively Determining Relative Weighting

    NASA Astrophysics Data System (ADS)

    Wang, Z.; Kato, T.; Wang, Y.

    2015-12-01

    The spatiotemporal fault slip history of the 2008 Iwate-Miyagi Nairiku earthquake, Japan, is obtained by the joint inversion of 1-Hz GPS waveforms and near-field strong motion records. 1-Hz GPS data from GEONET is processed by GAMIT/GLOBK and then a low-pass filter of 0.05 Hz is applied. The ground surface strong motion records from stations of K-NET and Kik-Net are band-pass filtered for the range of 0.05 ~ 0.3 Hz and integrated once to obtain velocity. The joint inversion exploits a broader frequency band for near-field ground motions, which provides excellent constraints for both the detailed slip history and slip distribution. A fully Bayesian inversion method is performed to simultaneously and objectively determine the rupture model, the unknown relative weighting of multiple data sets and the unknown smoothing hyperparameters. The preferred rupture model is stable for different choices of velocity structure model and station distribution, with maximum slip of ~ 8.0 m and seismic moment of 2.9 × 1019 Nm (Mw 6.9). By comparison with the single inversion of strong motion records, the cumulative slip distribution of joint inversion shows sparser slip distribution with two slip asperities. One common slip asperity extends from the hypocenter southeastward to the ground surface of breakage; another slip asperity, which is unique for joint inversion contributed by 1-Hz GPS waveforms, appears in the deep part of fault where very few aftershocks are occurring. The differential moment rate function of joint and single inversions obviously indicates that rich high frequency waves are radiated in the first three seconds but few low frequency waves.

  7. Characterizing Arctic mixed-phase cloud structure and its relationship with humidity and temperature inversion using ARM NSA observations

    DOE PAGES

    Qiu, Shaoyue; Dong, Xiquan; Xi, Baike; ...

    2015-07-20

    In this work, the characteristics of the Arctic mixed-phase cloud (AMC) have been investigated using data collected at the Atmospheric Radiation Measurement North Slope Alaska site from October 2006 to September 2009. AMC has an annual occurrence frequency of 42.3%, which includes 18.7% of single-layered AMCs and 23.6% for multiple layers. Two cloud base heights (CBHs) are defined from ceilometer and micropulse lidar (MPL) measurements. For single-layered AMC, the ceilometer-derived CBH represents the base of the liquid-dominant layer near the cloud top, while MPL-derived CBH represents base of the lower ice-dominant layer. The annual mean CBHs from ceilometer and MPLmore » measurements are 1.0 km and 0.6 km, respectively, with the largest difference (~1.0 km) occurring from December to March and the smallest difference in September. The humidity inversion occurrence decreases with increasing humidity inversion intensity (stronger in summer than in winter). During the winter months, AMC occurrences increase from 15% to 35% when the inversion intensity increases from 0.1 to 0.9 g/kg. On the contrary, despite a higher frequency of strong humidity inversion in summer, AMC occurrences are nearly invariant for different inversion intensities. On average, humidity and temperature inversion frequencies of occurrence above an AMC are 5 and 8 times, respectively, as high as those below an AMC. The strong inversion occurrences for both humidity and temperature above an AMC provide the moisture sources from above for the formation and maintenance of AMCs. In conclusion, this result helps to reconcile the persistency of AMCs even when the Arctic surface is covered by snow and ice.« less

  8. Morphological MRI characteristics of recent small subcortical infarcts.

    PubMed

    Gattringer, Thomas; Eppinger, Sebastian; Pinter, Daniela; Pirpamer, Lukas; Berghold, Andrea; Wünsch, Gerit; Ropele, Stefan; Wardlaw, Joanna M; Enzinger, Christian; Fazekas, Franz

    2015-10-01

    New imaging criteria for recent small subcortical infarcts have recently been proposed, replacing the earlier term 'lacunar infarction', but their applicability and impact on lesion selection is yet unknown. To collect information on the morphologic characteristics and variability of recent small subcortical infarcts on magnetic resonance imaging in regard to lesion location and demographic variables. We identified all patients with acute stroke and cerebral magnetic resonance imaging from 2008 to 2013 in our hospital database and selected those with a single recent small subcortical infarct defined by an estimated maximal axial diameter of 20 mm. Recent small subcortical infarcts were segmented on diffusion-weighted imaging and fluid-attenuated inversion recovery sequence to calculate the largest axial and longitudinal diameter and lesion volume. We assessed morphometric differences of recent small subcortical infarcts regarding location and demographic variables and the impact of different recent small subcortical infarct definitions on lesion selection. Three hundred forty-four patients (median age 72; range 25-92 years, 65% male) were selected. Most recent small subcortical infarcts were located in the basal ganglia (n = 111), followed by pons (n = 92), thalamus (n = 77), and centrum semiovale (n = 64). Quantitative measurements confirmed visual assessment of the axial diameter in 95%. All morphometric variables were strongly intercorrelated and comparable on diffusion-weighted imaging and fluid-attenuated inversion recovery sequence. Recent small subcortical infarcts in the basal ganglia were significantly larger both in the axial and longitudinal direction compared with other regions. Dichotomization of recent small subcortical infarcts according to axial (≤ / >15 mm) or longitudinal (≤ / >20 mm) sizes resulted in different regional frequencies and distributions. Age, gender, and time from stroke onset to magnetic resonance imaging did not influence lesion metrics or the distribution of recent small subcortical infarcts. Our study confirms the recent neuroimaging criteria for recent small subcortical infarcts as a practical concept. Definitions of the maximal axial and longitudinal diameter have a significant impact on the frequency and distribution of selected infarcts, which has to be considered for future studies. © 2015 World Stroke Organization.

  9. A forward model and conjugate gradient inversion technique for low-frequency ultrasonic imaging.

    PubMed

    van Dongen, Koen W A; Wright, William M D

    2006-10-01

    Emerging methods of hyperthermia cancer treatment require noninvasive temperature monitoring, and ultrasonic techniques show promise in this regard. Various tomographic algorithms are available that reconstruct sound speed or contrast profiles, which can be related to temperature distribution. The requirement of a high enough frequency for adequate spatial resolution and a low enough frequency for adequate tissue penetration is a difficult compromise. In this study, the feasibility of using low frequency ultrasound for imaging and temperature monitoring was investigated. The transient probing wave field had a bandwidth spanning the frequency range 2.5-320.5 kHz. The results from a forward model which computed the propagation and scattering of low-frequency acoustic pressure and velocity wave fields were used to compare three imaging methods formulated within the Born approximation, representing two main types of reconstruction. The first uses Fourier techniques to reconstruct sound-speed profiles from projection or Radon data based on optical ray theory, seen as an asymptotical limit for comparison. The second uses backpropagation and conjugate gradient inversion methods based on acoustical wave theory. The results show that the accuracy in localization was 2.5 mm or better when using low frequencies and the conjugate gradient inversion scheme, which could be used for temperature monitoring.

  10. Multiple Frequency Contrast Source Inversion Method for Vertical Electromagnetic Profiling: 2D Simulation Results and Analyses

    NASA Astrophysics Data System (ADS)

    Li, Jinghe; Song, Linping; Liu, Qing Huo

    2016-02-01

    A simultaneous multiple frequency contrast source inversion (CSI) method is applied to reconstructing hydrocarbon reservoir targets in a complex multilayered medium in two dimensions. It simulates the effects of a salt dome sedimentary formation in the context of reservoir monitoring. In this method, the stabilized biconjugate-gradient fast Fourier transform (BCGS-FFT) algorithm is applied as a fast solver for the 2D volume integral equation for the forward computation. The inversion technique with CSI combines the efficient FFT algorithm to speed up the matrix-vector multiplication and the stable convergence of the simultaneous multiple frequency CSI in the iteration process. As a result, this method is capable of making quantitative conductivity image reconstruction effectively for large-scale electromagnetic oil exploration problems, including the vertical electromagnetic profiling (VEP) survey investigated here. A number of numerical examples have been demonstrated to validate the effectiveness and capacity of the simultaneous multiple frequency CSI method for a limited array view in VEP.

  11. Seismic tomography of the southern California crust based on spectral-element and adjoint methods

    NASA Astrophysics Data System (ADS)

    Tape, Carl; Liu, Qinya; Maggi, Alessia; Tromp, Jeroen

    2010-01-01

    We iteratively improve a 3-D tomographic model of the southern California crust using numerical simulations of seismic wave propagation based on a spectral-element method (SEM) in combination with an adjoint method. The initial 3-D model is provided by the Southern California Earthquake Center. The data set comprises three-component seismic waveforms (i.e. both body and surface waves), filtered over the period range 2-30 s, from 143 local earthquakes recorded by a network of 203 stations. Time windows for measurements are automatically selected by the FLEXWIN algorithm. The misfit function in the tomographic inversion is based on frequency-dependent multitaper traveltime differences. The gradient of the misfit function and related finite-frequency sensitivity kernels for each earthquake are computed using an adjoint technique. The kernels are combined using a source subspace projection method to compute a model update at each iteration of a gradient-based minimization algorithm. The inversion involved 16 iterations, which required 6800 wavefield simulations. The new crustal model, m16, is described in terms of independent shear (VS) and bulk-sound (VB) wave speed variations. It exhibits strong heterogeneity, including local changes of +/-30 per cent with respect to the initial 3-D model. The model reveals several features that relate to geological observations, such as sedimentary basins, exhumed batholiths, and contrasting lithologies across faults. The quality of the new model is validated by quantifying waveform misfits of full-length seismograms from 91 earthquakes that were not used in the tomographic inversion. The new model provides more accurate synthetic seismograms that will benefit seismic hazard assessment.

  12. Adjoint Tomography of the Southern California Crust (Invited) (Invited)

    NASA Astrophysics Data System (ADS)

    Tape, C.; Liu, Q.; Maggi, A.; Tromp, J.

    2009-12-01

    We iteratively improve a three-dimensional tomographic model of the southern California crust using numerical simulations of seismic wave propagation based on a spectral-element method (SEM) in combination with an adjoint method. The initial 3D model is provided by the Southern California Earthquake Center. The dataset comprises three-component seismic waveforms (i.e. both body and surface waves), filtered over the period range 2-30 s, from 143 local earthquakes recorded by a network of 203 stations. Time windows for measurements are automatically selected by the FLEXWIN algorithm. The misfit function in the tomographic inversion is based on frequency-dependent multitaper traveltime differences. The gradient of the misfit function and related finite-frequency sensitivity kernels for each earthquake are computed using an adjoint technique. The kernels are combined using a source subspace projection method to compute a model update at each iteration of a gradient-based minimization algorithm. The inversion involved 16 iterations, which required 6800 wavefield simulations and a total of 0.8 million CPU hours. The new crustal model, m16, is described in terms of independent shear (Vs) and bulk-sound (Vb) wavespeed variations. It exhibits strong heterogeneity, including local changes of ±30% with respect to the initial 3D model. The model reveals several features that relate to geologic observations, such as sedimentary basins, exhumed batholiths, and contrasting lithologies across faults. The quality of the new model is validated by quantifying waveform misfits of full-length seismograms from 91 earthquakes that were not used in the tomographic inversion. The new model provides more accurate synthetic seismograms that will benefit seismic hazard assessment.

  13. Regularized inversion of controlled source audio-frequency magnetotelluric data in horizontally layered transversely isotropic media

    NASA Astrophysics Data System (ADS)

    Zhou, Jianmei; Wang, Jianxun; Shang, Qinglong; Wang, Hongnian; Yin, Changchun

    2014-04-01

    We present an algorithm for inverting controlled source audio-frequency magnetotelluric (CSAMT) data in horizontally layered transversely isotropic (TI) media. The popular inversion method parameterizes the media into a large number of layers which have fixed thickness and only reconstruct the conductivities (e.g. Occam's inversion), which does not enable the recovery of the sharp interfaces between layers. In this paper, we simultaneously reconstruct all the model parameters, including both the horizontal and vertical conductivities and layer depths. Applying the perturbation principle and the dyadic Green's function in TI media, we derive the analytic expression of Fréchet derivatives of CSAMT responses with respect to all the model parameters in the form of Sommerfeld integrals. A regularized iterative inversion method is established to simultaneously reconstruct all the model parameters. Numerical results show that the inverse algorithm, including the depths of the layer interfaces, can significantly improve the inverse results. It can not only reconstruct the sharp interfaces between layers, but also can obtain conductivities close to the true value.

  14. Further results on open-loop compensation of rate-dependent hysteresis in a magnetostrictive actuator with the Prandtl-Ishlinskii model

    NASA Astrophysics Data System (ADS)

    Al Janaideh, Mohammad; Aljanaideh, Omar

    2018-05-01

    Apart from the output-input hysteresis loops, the magnetostrictive actuators also exhibit asymmetry and saturation, particularly under moderate to large magnitude inputs and at relatively higher frequencies. Such nonlinear input-output characteristics could be effectively characterized by a rate-dependent Prandtl-Ishlinskii model in conjunction with a function of deadband operators. In this study, an inverse model is formulated to seek real-time compensation of rate-dependent and asymmetric hysteresis nonlinearities of a Terfenol-D magnetostrictive actuator. The inverse model is formulated with the inverse of the rate-dependent Prandtl-Ishlinskii model, satisfying the threshold dilation condition, with the inverse of the deadband function. The inverse model was subsequently applied to the hysteresis model as a feedforward compensator. The proposed compensator is applied as a feedforward compensator to the actuator hardware to study its potential for rate-dependent and asymmetric hysteresis loops. The experimental results are obtained under harmonic and complex harmonic inputs further revealed that the inverse compensator can substantially suppress the hysteresis and output asymmetry nonlinearities in the entire frequency range considered in the study.

  15. Inversion polymorphism and extra bristles in Indian natural populations of Drosophila ananassae: joint variation.

    PubMed

    Das, A; Mohanty, S; Parida, B B

    1994-10-01

    Five Indian natural populations of Drosophila ananassae were analysed for chromosome inversions and the presence of individuals with extra scutellar bristles in the F1 progeny of isofemale lines initiated from naturally impregnated females. Three commonly occurring inversions were found in these populations with varying frequencies as was the number of individuals with extra bristles (e.b.). Female individuals were more often found to carry extra scutellar bristles than were males. This result reveals that polygenic loci responsible for the determination of e.b. are widespread in Indian natural populations of D. ananassae. A significant positive correlation between the inversion frequency and the number of individuals with e.b. was detected in the isofemale lines of all the five populations. The 2L inversion, alpha, was found to be closely associated with individuals with the e.b. phenotype. The observed results are compared with earlier results obtained for D. melanogaster. The association of the alpha inversion with the e.b. phenotype is discussed in relation to chromosomal evolution in the melanogaster species group.

  16. Stability and uncertainty of finite-fault slip inversions: Application to the 2004 Parkfield, California, earthquake

    USGS Publications Warehouse

    Hartzell, S.; Liu, P.; Mendoza, C.; Ji, C.; Larson, K.M.

    2007-01-01

    The 2004 Parkfield, California, earthquake is used to investigate stability and uncertainty aspects of the finite-fault slip inversion problem with different a priori model assumptions. We utilize records from 54 strong ground motion stations and 13 continuous, 1-Hz sampled, geodetic instruments. Two inversion procedures are compared: a linear least-squares subfault-based methodology and a nonlinear global search algorithm. These two methods encompass a wide range of the different approaches that have been used to solve the finite-fault slip inversion problem. For the Parkfield earthquake and the inversion of velocity or displacement waveforms, near-surface related site response (top 100 m, frequencies above 1 Hz) is shown to not significantly affect the solution. Results are also insensitive to selection of slip rate functions with similar duration and to subfault size if proper stabilizing constraints are used. The linear and nonlinear formulations yield consistent results when the same limitations in model parameters are in place and the same inversion norm is used. However, the solution is sensitive to the choice of inversion norm, the bounds on model parameters, such as rake and rupture velocity, and the size of the model fault plane. The geodetic data set for Parkfield gives a slip distribution different from that of the strong-motion data, which may be due to the spatial limitation of the geodetic stations and the bandlimited nature of the strong-motion data. Cross validation and the bootstrap method are used to set limits on the upper bound for rupture velocity and to derive mean slip models and standard deviations in model parameters. This analysis shows that slip on the northwestern half of the Parkfield rupture plane from the inversion of strong-motion data is model dependent and has a greater uncertainty than slip near the hypocenter.

  17. Fast Evolution from Precast Bricks: Genomics of Young Freshwater Populations of Threespine Stickleback Gasterosteus aculeatus

    PubMed Central

    Terekhanova, Nadezhda V.; Logacheva, Maria D.; Penin, Aleksey A.; Neretina, Tatiana V.; Barmintseva, Anna E.; Bazykin, Georgii A.; Kondrashov, Alexey S.; Mugue, Nikolai S.

    2014-01-01

    Adaptation is driven by natural selection; however, many adaptations are caused by weak selection acting over large timescales, complicating its study. Therefore, it is rarely possible to study selection comprehensively in natural environments. The threespine stickleback (Gasterosteus aculeatus) is a well-studied model organism with a short generation time, small genome size, and many genetic and genomic tools available. Within this originally marine species, populations have recurrently adapted to freshwater all over its range. This evolution involved extensive parallelism: pre-existing alleles that adapt sticklebacks to freshwater habitats, but are also present at low frequencies in marine populations, have been recruited repeatedly. While a number of genomic regions responsible for this adaptation have been identified, the details of selection remain poorly understood. Using whole-genome resequencing, we compare pooled genomic samples from marine and freshwater populations of the White Sea basin, and identify 19 short genomic regions that are highly divergent between them, including three known inversions. 17 of these regions overlap protein-coding genes, including a number of genes with predicted functions that are relevant for adaptation to the freshwater environment. We then analyze four additional independently derived young freshwater populations of known ages, two natural and two artificially established, and use the observed shifts of allelic frequencies to estimate the strength of positive selection. Adaptation turns out to be quite rapid, indicating strong selection acting simultaneously at multiple regions of the genome, with selection coefficients of up to 0.27. High divergence between marine and freshwater genotypes, lack of reduction in polymorphism in regions responsible for adaptation, and high frequencies of freshwater alleles observed even in young freshwater populations are all consistent with rapid assembly of G. aculeatus freshwater genotypes from pre-existing genomic regions of adaptive variation, with strong selection that favors this assembly acting simultaneously at multiple loci. PMID:25299485

  18. Fast evolution from precast bricks: genomics of young freshwater populations of threespine stickleback Gasterosteus aculeatus.

    PubMed

    Terekhanova, Nadezhda V; Logacheva, Maria D; Penin, Aleksey A; Neretina, Tatiana V; Barmintseva, Anna E; Bazykin, Georgii A; Kondrashov, Alexey S; Mugue, Nikolai S

    2014-10-01

    Adaptation is driven by natural selection; however, many adaptations are caused by weak selection acting over large timescales, complicating its study. Therefore, it is rarely possible to study selection comprehensively in natural environments. The threespine stickleback (Gasterosteus aculeatus) is a well-studied model organism with a short generation time, small genome size, and many genetic and genomic tools available. Within this originally marine species, populations have recurrently adapted to freshwater all over its range. This evolution involved extensive parallelism: pre-existing alleles that adapt sticklebacks to freshwater habitats, but are also present at low frequencies in marine populations, have been recruited repeatedly. While a number of genomic regions responsible for this adaptation have been identified, the details of selection remain poorly understood. Using whole-genome resequencing, we compare pooled genomic samples from marine and freshwater populations of the White Sea basin, and identify 19 short genomic regions that are highly divergent between them, including three known inversions. 17 of these regions overlap protein-coding genes, including a number of genes with predicted functions that are relevant for adaptation to the freshwater environment. We then analyze four additional independently derived young freshwater populations of known ages, two natural and two artificially established, and use the observed shifts of allelic frequencies to estimate the strength of positive selection. Adaptation turns out to be quite rapid, indicating strong selection acting simultaneously at multiple regions of the genome, with selection coefficients of up to 0.27. High divergence between marine and freshwater genotypes, lack of reduction in polymorphism in regions responsible for adaptation, and high frequencies of freshwater alleles observed even in young freshwater populations are all consistent with rapid assembly of G. aculeatus freshwater genotypes from pre-existing genomic regions of adaptive variation, with strong selection that favors this assembly acting simultaneously at multiple loci.

  19. Investigation of geological structures with a view to HLRW disposal, as revealed through 3D inversion of aeromagnetic and gravity data and the results of CSAMT exploration

    NASA Astrophysics Data System (ADS)

    An, Zhiguo; Di, Qingyun

    2016-12-01

    The Alxa area in Inner Mongolia has been selected as a possible site for geological disposal of high-level radioactive waste (HLRW). Based on results of a previous study on crustal stability, the Tamusu rock mass has been chosen as the target. To determine the geological structure of this rock mass, aeromagnetic and gravity data are collected and inverted. Three-dimensional (3D) inversion horizontal slices show that the internal density of the rock mass and the distribution of magnetic properties are not uniform, with fractures and fragmentation being present. To confirm this result, the controlled source audio-frequency magnetotelluric method (CSAMT) was applied to explore the geological structures, the typical CSAMT sounding curve was analyzed, and the response characteristics of the geological structure and surrounding rock are distinguished. The original data were processed and interpreted in combination with data from surface geology and drilling and logging data. It is found that the CSAMT results were consistent with those from 3D inversion of the gravity and magnetic data, confirming the existence of fractures and fragmentation in the exploration area.

  20. Automatic 3D Moment tensor inversions for southern California earthquakes

    NASA Astrophysics Data System (ADS)

    Liu, Q.; Tape, C.; Friberg, P.; Tromp, J.

    2008-12-01

    We present a new source mechanism (moment-tensor and depth) catalog for about 150 recent southern California earthquakes with Mw ≥ 3.5. We carefully select the initial solutions from a few available earthquake catalogs as well as our own preliminary 3D moment tensor inversion results. We pick useful data windows by assessing the quality of fits between the data and synthetics using an automatic windowing package FLEXWIN (Maggi et al 2008). We compute the source Fréchet derivatives of moment-tensor elements and depth for a recent 3D southern California velocity model inverted based upon finite-frequency event kernels calculated by the adjoint methods and a nonlinear conjugate gradient technique with subspace preconditioning (Tape et al 2008). We then invert for the source mechanisms and event depths based upon the techniques introduced by Liu et al 2005. We assess the quality of this new catalog, as well as the other existing ones, by computing the 3D synthetics for the updated 3D southern California model. We also plan to implement the moment-tensor inversion methods to automatically determine the source mechanisms for earthquakes with Mw ≥ 3.5 in southern California.

  1. Application of Carbonate Reservoir using waveform inversion and reverse-time migration methods

    NASA Astrophysics Data System (ADS)

    Kim, W.; Kim, H.; Min, D.; Keehm, Y.

    2011-12-01

    Recent exploration targets of oil and gas resources are deeper and more complicated subsurface structures, and carbonate reservoirs have become one of the attractive and challenging targets in seismic exploration. To increase the rate of success in oil and gas exploration, it is required to delineate detailed subsurface structures. Accordingly, migration method is more important factor in seismic data processing for the delineation. Seismic migration method has a long history, and there have been developed lots of migration techniques. Among them, reverse-time migration is promising, because it can provide reliable images for the complicated model even in the case of significant velocity contrasts in the model. The reliability of seismic migration images is dependent on the subsurface velocity models, which can be extracted in several ways. These days, geophysicists try to obtain velocity models through seismic full waveform inversion. Since Lailly (1983) and Tarantola (1984) proposed that the adjoint state of wave equations can be used in waveform inversion, the back-propagation techniques used in reverse-time migration have been used in waveform inversion, which accelerated the development of waveform inversion. In this study, we applied acoustic waveform inversion and reverse-time migration methods to carbonate reservoir models with various reservoir thicknesses to examine the feasibility of the methods in delineating carbonate reservoir models. We first extracted subsurface material properties from acoustic waveform inversion, and then applied reverse-time migration using the inverted velocities as a background model. The waveform inversion in this study used back-propagation technique, and conjugate gradient method was used in optimization. The inversion was performed using the frequency-selection strategy. Finally waveform inversion results showed that carbonate reservoir models are clearly inverted by waveform inversion and migration images based on the inversion results are quite reliable. Different thicknesses of reservoir models were also described and the results revealed that the lower boundary of the reservoir was not delineated because of energy loss. From these results, it was noted that carbonate reservoirs can be properly imaged and interpreted by waveform inversion and reverse-time migration methods. This work was supported by the Energy Resources R&D program of the Korea Institute of Energy Technology Evaluation and Planning (KETEP) grant funded by the Korea government Ministry of Knowledge Economy (No. 2009201030001A, No. 2010T100200133) and the Brain Korea 21 project of Energy System Engineering.

  2. Time-frequency domain SNR estimation and its application in seismic data processing

    NASA Astrophysics Data System (ADS)

    Zhao, Yan; Liu, Yang; Li, Xuxuan; Jiang, Nansen

    2014-08-01

    Based on an approach estimating frequency domain signal-to-noise ratio (FSNR), we propose a method to evaluate time-frequency domain signal-to-noise ratio (TFSNR). This method adopts short-time Fourier transform (STFT) to estimate instantaneous power spectrum of signal and noise, and thus uses their ratio to compute TFSNR. Unlike FSNR describing the variation of SNR with frequency only, TFSNR depicts the variation of SNR with time and frequency, and thus better handles non-stationary seismic data. By considering TFSNR, we develop methods to improve the effects of inverse Q filtering and high frequency noise attenuation in seismic data processing. Inverse Q filtering considering TFSNR can better solve the problem of amplitude amplification of noise. The high frequency noise attenuation method considering TFSNR, different from other de-noising methods, distinguishes and suppresses noise using an explicit criterion. Examples of synthetic and real seismic data illustrate the correctness and effectiveness of the proposed methods.

  3. A cut-&-paste strategy for the 3-D inversion of helicopter-borne electromagnetic data - I. 3-D inversion using the explicit Jacobian and a tensor-based formulation

    NASA Astrophysics Data System (ADS)

    Scheunert, M.; Ullmann, A.; Afanasjew, M.; Börner, R.-U.; Siemon, B.; Spitzer, K.

    2016-06-01

    We present an inversion concept for helicopter-borne frequency-domain electromagnetic (HEM) data capable of reconstructing 3-D conductivity structures in the subsurface. Standard interpretation procedures often involve laterally constrained stitched 1-D inversion techniques to create pseudo-3-D models that are largely representative for smoothly varying conductivity distributions in the subsurface. Pronounced lateral conductivity changes may, however, produce significant artifacts that can lead to serious misinterpretation. Still, 3-D inversions of entire survey data sets are numerically very expensive. Our approach is therefore based on a cut-&-paste strategy whereupon the full 3-D inversion needs to be applied only to those parts of the survey where the 1-D inversion actually fails. The introduced 3-D Gauss-Newton inversion scheme exploits information given by a state-of-the-art (laterally constrained) 1-D inversion. For a typical HEM measurement, an explicit representation of the Jacobian matrix is inevitable which is caused by the unique transmitter-receiver relation. We introduce tensor quantities which facilitate the matrix assembly of the forward operator as well as the efficient calculation of the Jacobian. The finite difference forward operator incorporates the displacement currents because they may seriously affect the electromagnetic response at frequencies above 100. Finally, we deliver the proof of concept for the inversion using a synthetic data set with a noise level of up to 5%.

  4. Genetic architecture and balancing selection: the life and death of differentiated variants.

    PubMed

    Llaurens, Violaine; Whibley, Annabel; Joron, Mathieu

    2017-05-01

    Balancing selection describes any form of natural selection, which results in the persistence of multiple variants of a trait at intermediate frequencies within populations. By offering up a snapshot of multiple co-occurring functional variants and their interactions, systems under balancing selection can reveal the evolutionary mechanisms favouring the emergence and persistence of adaptive variation in natural populations. We here focus on the mechanisms by which several functional variants for a given trait can arise, a process typically requiring multiple epistatic mutations. We highlight how balancing selection can favour specific features in the genetic architecture and review the evolutionary and molecular mechanisms shaping this architecture. First, balancing selection affects the number of loci underlying differentiated traits and their respective effects. Control by one or few loci favours the persistence of differentiated functional variants by limiting intergenic recombination, or its impact, and may sometimes lead to the evolution of supergenes. Chromosomal rearrangements, particularly inversions, preventing adaptive combinations from being dissociated are increasingly being noted as features of such systems. Similarly, due to the frequency of heterozygotes maintained by balancing selection, dominance may be a key property of adaptive variants. High heterozygosity and limited recombination also influence associated genetic load, as linked recessive deleterious mutations may be sheltered. The capture of deleterious elements in a locus under balancing selection may reinforce polymorphism by further promoting heterozygotes. Finally, according to recent genomewide scans, balanced polymorphism might be more pervasive than generally thought. We stress the need for both functional and ecological studies to characterize the evolutionary mechanisms operating in these systems. © 2017 John Wiley & Sons Ltd.

  5. Phenology of Scramble Polygyny in a Wild Population of Chrysolemid Beetles: The Opportunity for and the Strength of Sexual Selection

    PubMed Central

    Baena, Martha Lucía; Macías-Ordóñez, Rogelio

    2012-01-01

    Recent debate has highlighted the importance of estimating both the strength of sexual selection on phenotypic traits, and the opportunity for sexual selection. We describe seasonal fluctuations in mating dynamics of Leptinotarsa undecimlineata (Coleoptera: Chrysomelidae). We compared several estimates of the opportunity for, and the strength of, sexual selection and male precopulatory competition over the reproductive season. First, using a null model, we suggest that the ratio between observed values of the opportunity for sexual selections and their expected value under random mating results in unbiased estimates of the actual nonrandom mating behavior of the population. Second, we found that estimates for the whole reproductive season often misrepresent the actual value at any given time period. Third, mating differentials on male size and mobility, frequency of male fighting and three estimates of the opportunity for sexual selection provide contrasting but complementary information. More intense sexual selection associated to male mobility, but not to male size, was observed in periods with high opportunity for sexual selection and high frequency of male fights. Fourth, based on parameters of spatial and temporal aggregation of female receptivity, we describe the mating system of L. undecimlineata as a scramble mating polygyny in which the opportunity for sexual selection varies widely throughout the season, but the strength of sexual selection on male size remains fairly weak, while male mobility inversely covaries with mating success. We suggest that different estimates for the opportunity for, and intensity of, sexual selection should be applied in order to discriminate how different behavioral and demographic factors shape the reproductive dynamic of populations. PMID:22761675

  6. Saturation sampling for spatial variation in multiple air pollutants across an inversion-prone metropolitan area of complex terrain

    PubMed Central

    2014-01-01

    Background Characterizing intra-urban variation in air quality is important for epidemiological investigation of health outcomes and disparities. To date, however, few studies have been designed to capture spatial variation during select hours of the day, or to examine the roles of meteorology and complex terrain in shaping intra-urban exposure gradients. Methods We designed a spatial saturation monitoring study to target local air pollution sources, and to understand the role of topography and temperature inversions on fine-scale pollution variation by systematically allocating sampling locations across gradients in key local emissions sources (vehicle traffic, industrial facilities) and topography (elevation) in the Pittsburgh area. Street-level integrated samples of fine particulate matter (PM2.5), black carbon (BC), nitrogen dioxide (NO2), sulfur dioxide (SO2), and ozone (O3) were collected during morning rush and probable inversion hours (6-11 AM), during summer and winter. We hypothesized that pollution concentrations would be: 1) higher under inversion conditions, 2) exacerbated in lower-elevation areas, and 3) vary by season. Results During July - August 2011 and January - March 2012, we observed wide spatial and seasonal variability in pollution concentrations, exceeding the range measured at regulatory monitors. We identified elevated concentrations of multiple pollutants at lower-elevation sites, and a positive association between inversion frequency and NO2 concentration. We examined temporal adjustment methods for deriving seasonal concentration estimates, and found that the appropriate reference temporal trend differs between pollutants. Conclusions Our time-stratified spatial saturation approach found some evidence for modification of inversion-concentration relationships by topography, and provided useful insights for refining and interpreting GIS-based pollution source indicators for Land Use Regression modeling. PMID:24735818

  7. Saturation sampling for spatial variation in multiple air pollutants across an inversion-prone metropolitan area of complex terrain.

    PubMed

    Shmool, Jessie Lc; Michanowicz, Drew R; Cambal, Leah; Tunno, Brett; Howell, Jeffery; Gillooly, Sara; Roper, Courtney; Tripathy, Sheila; Chubb, Lauren G; Eisl, Holger M; Gorczynski, John E; Holguin, Fernando E; Shields, Kyra Naumoff; Clougherty, Jane E

    2014-04-16

    Characterizing intra-urban variation in air quality is important for epidemiological investigation of health outcomes and disparities. To date, however, few studies have been designed to capture spatial variation during select hours of the day, or to examine the roles of meteorology and complex terrain in shaping intra-urban exposure gradients. We designed a spatial saturation monitoring study to target local air pollution sources, and to understand the role of topography and temperature inversions on fine-scale pollution variation by systematically allocating sampling locations across gradients in key local emissions sources (vehicle traffic, industrial facilities) and topography (elevation) in the Pittsburgh area. Street-level integrated samples of fine particulate matter (PM2.5), black carbon (BC), nitrogen dioxide (NO2), sulfur dioxide (SO2), and ozone (O3) were collected during morning rush and probable inversion hours (6-11 AM), during summer and winter. We hypothesized that pollution concentrations would be: 1) higher under inversion conditions, 2) exacerbated in lower-elevation areas, and 3) vary by season. During July - August 2011 and January - March 2012, we observed wide spatial and seasonal variability in pollution concentrations, exceeding the range measured at regulatory monitors. We identified elevated concentrations of multiple pollutants at lower-elevation sites, and a positive association between inversion frequency and NO2 concentration. We examined temporal adjustment methods for deriving seasonal concentration estimates, and found that the appropriate reference temporal trend differs between pollutants. Our time-stratified spatial saturation approach found some evidence for modification of inversion-concentration relationships by topography, and provided useful insights for refining and interpreting GIS-based pollution source indicators for Land Use Regression modeling.

  8. Electromagnetic inverse scattering

    NASA Technical Reports Server (NTRS)

    Bojarski, N. N.

    1972-01-01

    A three-dimensional electromagnetic inverse scattering identity, based on the physical optics approximation, is developed for the monostatic scattered far field cross section of perfect conductors. Uniqueness of this inverse identity is proven. This identity requires complete scattering information for all frequencies and aspect angles. A nonsingular integral equation is developed for the arbitrary case of incomplete frequence and/or aspect angle scattering information. A general closed-form solution to this integral equation is developed, which yields the shape of the scatterer from such incomplete information. A specific practical radar solution is presented. The resolution of this solution is developed, yielding short-pulse target resolution radar system parameter equations. The special cases of two- and one-dimensional inverse scattering and the special case of a priori knowledge of scatterer symmetry are treated in some detail. The merits of this solution over the conventional radar imaging technique are discussed.

  9. Feedforward Controller of Ill-Conditioned Hysteresis Using Singularity-Free Prandtl–Ishlinskii Model

    PubMed Central

    Tan, U-Xuan; Latt, Win Tun; Shee, Cheng Yap; Riviere, Cameron N.; Ang, Wei Tech

    2009-01-01

    Piezoelectric, magnetostrictive, and shape memory alloy actuators are gaining importance in high-frequency precision applications constrained by space. Their intrinsic hysteretic behavior makes control difficult. The Prandtl–Ishlinskii (PI) operator can model hysteresis well, albeit a major inadequacy: the inverse operator does not exist when the hysteretic curve gradient is not positive definite, i.e., ill condition occurs when slope is negative. An inevitable tradeoff between modeling accuracy and inversion stability exists. The hysteretic modeling improves with increasing number of play operators. But as the piecewise continuous interval of each operator reduces, the model tends to be ill-conditioned, especially at the turning points. Similar ill-conditioned situation arises when these actuators move heavy loads or operate at high frequency. This paper proposes an extended PI operator to map hysteresis to a domain where inversion is well behaved. The inverse weights are then evaluated to determine the inverse hysteresis model for the feedforward controller. For illustration purpose, a piezoelectric actuator is used. PMID:19936032

  10. Effect of glare on simple reaction time.

    PubMed

    Aguirre, Rolando C; Colombo, Elisa M; Barraza, José F

    2008-07-01

    We systematized the study of the effect of glare on reaction time (RT), for visual conditions similar to the ones found during night driving: Mesopic range of adaptation (0.14 cd/m2), glare levels of the order of those produced by car headlights (E(G)=15, 60 lx), suprathreshold luminance contrasts, and a variety of spatial frequencies covering the selected range of visibility (1, 2, 4, and 8 c/deg). We found that for the no-glare situation, RT increases with decreasing contrast and increasing spatial frequency, which agrees with previous findings. When data are plotted as a function of the inverse of contrast, RT varies linearly, with k--the RT-contrast factor of Pieron's law--representing the slope of the lines. The effect of glare on RT is an increase in the slope of these lines. This effect is different for each spatial frequency, which cannot be accounted for in the classic approach considering that glare can be replaced by a single veiling luminance. We show that the effect of glare on RT must be modeled by an equivalent glare luminance that depends on spatial frequency.

  11. Coalescent patterns for chromosomal inversions in divergent populations

    PubMed Central

    Guerrero, Rafael F.; Rousset, François; Kirkpatrick, Mark

    2012-01-01

    Chromosomal inversions allow genetic divergence of locally adapted populations by reducing recombination between chromosomes with different arrangements. Divergence between populations (or hybridization between species) is expected to leave signatures in the neutral genetic diversity of the inverted region. Quantitative expectations for these patterns, however, have not been obtained. Here, we develop coalescent models of neutral sites linked to an inversion polymorphism in two locally adapted populations. We consider two scenarios of local adaptation: selection on the inversion breakpoints and selection on alleles inside the inversion. We find that ancient inversion polymorphisms cause genetic diversity to depart dramatically from neutral expectations. Other situations, however, lead to patterns that may be difficult to detect; important determinants are the age of the inversion and the rate of gene flux between arrangements. We also study inversions under genetic drift, finding that they produce patterns similar to locally adapted inversions of intermediate age. Our results are consistent with empirical observations, and provide the foundation for quantitative analyses of the roles that inversions have played in speciation. PMID:22201172

  12. Genetic Mapping of Fixed Phenotypes: Disease Frequency as a Breed Characteristic

    PubMed Central

    Jones, Paul; Martin, Alan; Ostrander, Elaine A.; Lark, Karl G.

    2009-01-01

    Traits that have been stringently selected to conform to specific criteria in a closed population are phenotypic stereotypes. In dogs, Canis familiaris, such stereotypes have been produced by breeding for conformation, performance (behaviors), etc. We measured phenotypes on a representative sample to establish breed stereotypes. DNA samples from 147 dog breeds were used to characterize single nucleotide polymorphism allele frequencies for association mapping of breed stereotypes. We identified significant size loci (quantitative trait loci [QTLs]), implicating candidate genes appropriate to regulation of size (e.g., IGF1, IGF2BP2 SMAD2, etc.). Analysis of other morphological stereotypes, also under extreme selection, identified many additional significant loci. Behavioral loci for herding, pointing, and boldness implicated candidate genes appropriate to behavior (e.g., MC2R, DRD1, and PCDH9). Significant loci for longevity, a breed characteristic inversely correlated with breed size, were identified. The power of this approach to identify loci regulating the incidence of specific polygenic diseases is demonstrated by the association of a specific IGF1 haplotype with hip dysplasia, patella luxation, and pacreatitis. PMID:19321632

  13. Genetic mapping of fixed phenotypes: disease frequency as a breed characteristic.

    PubMed

    Chase, Kevin; Jones, Paul; Martin, Alan; Ostrander, Elaine A; Lark, Karl G

    2009-01-01

    Traits that have been stringently selected to conform to specific criteria in a closed population are phenotypic stereotypes. In dogs, Canis familiaris, such stereotypes have been produced by breeding for conformation, performance (behaviors), etc. We measured phenotypes on a representative sample to establish breed stereotypes. DNA samples from 147 dog breeds were used to characterize single nucleotide polymorphism allele frequencies for association mapping of breed stereotypes. We identified significant size loci (quantitative trait loci [QTLs]), implicating candidate genes appropriate to regulation of size (e.g., IGF1, IGF2BP2 SMAD2, etc.). Analysis of other morphological stereotypes, also under extreme selection, identified many additional significant loci. Behavioral loci for herding, pointing, and boldness implicated candidate genes appropriate to behavior (e.g., MC2R, DRD1, and PCDH9). Significant loci for longevity, a breed characteristic inversely correlated with breed size, were identified. The power of this approach to identify loci regulating the incidence of specific polygenic diseases is demonstrated by the association of a specific IGF1 haplotype with hip dysplasia, patella luxation, and pancreatitis.

  14. Nonreciprocal Surface Acoustic Waves in Multilayers with Magnetoelastic and Interfacial Dzyaloshinskii-Moriya Interactions

    NASA Astrophysics Data System (ADS)

    Verba, Roman; Lisenkov, Ivan; Krivorotov, Ilya; Tiberkevich, Vasil; Slavin, Andrei

    2018-06-01

    Surface acoustic waves (SAWs) propagating in a piezoelectric substrate covered with a thin ferromagnetic-heavy-metal bilayer are found to exhibit a substantial degree of nonreciprocity, i.e., the frequencies of these waves are nondegenerate with respect to the inversion of the SAW propagation direction. The simultaneous action of the magnetoelastic interaction in the ferromagnetic layer and the interfacial Dzyaloshinskii-Moriya interaction in the ferromagnetic-heavy-metal interface results in the openings of magnetoelastic band gaps in the SAW spectrum, and the frequency position of these band gaps is different for opposite SAW propagation directions. The band-gap widths and the frequency separation between them can be controlled by a proper selection of the magnetization angle and the thickness of the ferromagnetic layer. Using numerical simulations, we demonstrate that the isolation between SAWs propagating in opposite directions in such a system can exceed the direct SAW propagation losses by more than 1 order of magnitude.

  15. Inflammatory cytokine response and reduced heart rate variability in newborns with hypoxic-ischemic encephalopathy.

    PubMed

    Al-Shargabi, T; Govindan, R B; Dave, R; Metzler, M; Wang, Y; du Plessis, A; Massaro, A N

    2017-06-01

    To determine whether systemic inflammation-modulating cytokine expression is related to heart rate variability (HRV) in newborns with hypoxic-ischemic encephalopathy (HIE). The data from 30 newborns with HIE were analyzed. Cytokine levels (IL-2, IL-4, IL-6, IL-8, IL-10, IL-13, IL-1β, TNF-α, IFN-λ) were measured either at 24 h of cooling (n=5), 72 h of cooling (n=4) or at both timepoints (n=21). The following HRV metrics were quantified in the time domain: alpha_S, alpha_L, root mean square (RMS) at short time scales (RMS_S), RMS at long time scales (RMS_L), while low-frequency power (LF) and high-frequency power (HF) were quantified in the frequency domain. The relationships between HRV metrics and cytokines were evaluated using mixed-models. IL-6, IL-8, IL-10, and IL-13 levels were inversely related to selected HRV metrics. Inflammation-modulating cytokines may be important mediators in the autonomic dysfunction observed in newborns with HIE.

  16. A deterministic (non-stochastic) low frequency method for geoacoustic inversion.

    PubMed

    Tolstoy, A

    2010-06-01

    It is well known that multiple frequency sources are necessary for accurate geoacoustic inversion. This paper presents an inversion method which uses the low frequency (LF) spectrum only to estimate bottom properties even in the presence of expected errors in source location, phone depths, and ocean sound-speed profiles. Matched field processing (MFP) along a vertical array is used. The LF method first conducts an exhaustive search of the (five) parameter search space (sediment thickness, sound-speed at the top of the sediment layer, the sediment layer sound-speed gradient, the half-space sound-speed, and water depth) at 25 Hz and continues by retaining only the high MFP value parameter combinations. Next, frequency is slowly increased while again retaining only the high value combinations. At each stage of the process, only those parameter combinations which give high MFP values at all previous LF predictions are considered (an ever shrinking set). It is important to note that a complete search of each relevant parameter space seems to be necessary not only at multiple (sequential) frequencies but also at multiple ranges in order to eliminate sidelobes, i.e., false solutions. Even so, there are no mathematical guarantees that one final, unique "solution" will be found.

  17. A space efficient flexible pivot selection approach to evaluate determinant and inverse of a matrix.

    PubMed

    Jafree, Hafsa Athar; Imtiaz, Muhammad; Inayatullah, Syed; Khan, Fozia Hanif; Nizami, Tajuddin

    2014-01-01

    This paper presents new simple approaches for evaluating determinant and inverse of a matrix. The choice of pivot selection has been kept arbitrary thus they reduce the error while solving an ill conditioned system. Computation of determinant of a matrix has been made more efficient by saving unnecessary data storage and also by reducing the order of the matrix at each iteration, while dictionary notation [1] has been incorporated for computing the matrix inverse thereby saving unnecessary calculations. These algorithms are highly class room oriented, easy to use and implemented by students. By taking the advantage of flexibility in pivot selection, one may easily avoid development of the fractions by most. Unlike the matrix inversion method [2] and [3], the presented algorithms obviate the use of permutations and inverse permutations.

  18. Adjoint tomography of Europe

    NASA Astrophysics Data System (ADS)

    Zhu, H.; Bozdag, E.; Peter, D. B.; Tromp, J.

    2010-12-01

    We use spectral-element and adjoint methods to image crustal and upper mantle heterogeneity in Europe. The study area involves the convergent boundaries of the Eurasian, African and Arabian plates and the divergent boundary between the Eurasian and North American plates, making the tectonic structure of this region complex. Our goal is to iteratively fit observed seismograms and improve crustal and upper mantle images by taking advantage of 3D forward and inverse modeling techniques. We use data from 200 earthquakes with magnitudes between 5 and 6 recorded by 262 stations provided by ORFEUS. Crustal model Crust2.0 combined with mantle model S362ANI comprise the initial 3D model. Before the iterative adjoint inversion, we determine earthquake source parameters in the initial 3D model by using 3D Green functions and their Fréchet derivatives with respect to the source parameters (i.e., centroid moment tensor and location). The updated catalog is used in the subsequent structural inversion. Since we concentrate on upper mantle structures which involve anisotropy, transversely isotropic (frequency-dependent) traveltime sensitivity kernels are used in the iterative inversion. Taking advantage of the adjoint method, we use as many measurements as can obtain based on comparisons between observed and synthetic seismograms. FLEXWIN (Maggi et al., 2009) is used to automatically select measurement windows which are analyzed based on a multitaper technique. The bandpass ranges from 15 second to 150 second. Long-period surface waves and short-period body waves are combined in source relocations and structural inversions. A statistical assessments of traveltime anomalies and logarithmic waveform differences is used to characterize the inverted sources and structure.

  19. Lag compensation of optical fibers or thermocouples to achieve waveform fidelity in dynamic gas pyrometry

    NASA Technical Reports Server (NTRS)

    Warshawsky, I.

    1991-01-01

    Fidelity of waveform reproduction requires constant amplitude ratio and constant time lag of a temperature sensor's indication, at all frequencies of interest. However, heat-transfer type sensors usually cannot satisfy these requirements. Equations for the actual indication of a thermocouple and an optical-fiber pyrometer are given explicitly, in terms of sensor and flowing-gas properties. A practical, realistic design of each type of sensor behaves like a first-order system with amplitude-ratio attenuation inversely proportional to frequency when the frequency exceeds the corner frequency. Only at much higher frequencies does the amplitude-ratio attenuation for the optical fiber sensor become inversely proportional to the square root of the frequency. Design options for improving the frequency response are discussed. On-line electrical lag compensation, using a linear amplifier and a passive compensation network, can extend the corner frequency of the thermocouple 100-fold or more; a similar passive network can be used for the optical-fiber sensor. Design details for these networks are presented.

  20. Frequency-Dependent Rupture Processes for the 2011 Tohoku Earthquake

    NASA Astrophysics Data System (ADS)

    Miyake, H.

    2012-12-01

    The 2011 Tohoku earthquake is characterized by frequency-dependent rupture process [e.g., Ide et al., 2011; Wang and Mori, 2011; Yao et al., 2011]. For understanding rupture dynamics of this earthquake, it is extremely important to investigate wave-based source inversions for various frequency bands. The above frequency-dependent characteristics have been derived from teleseismic analyses. This study challenges to infer frequency-dependent rupture processes from strong motion waveforms of K-NET and KiK-net stations. The observations suggested three or more S-wave phases, and ground velocities at several near-source stations showed different arrivals of their long- and short-period components. We performed complex source spectral inversions with frequency-dependent phase weighting developed by Miyake et al. [2002]. The technique idealizes both the coherent and stochastic summation of waveforms using empirical Green's functions. Due to the limitation of signal-to-noise ratio of the empirical Green's functions, the analyzed frequency bands were set within 0.05-10 Hz. We assumed a fault plane with 480 km in length by 180 km in width with a single time window for rupture following Koketsu et al. [2011] and Asano and Iwata [2012]. The inversion revealed source ruptures expanding from the hypocenter, and generated sharp slip-velocity intensities at the down-dip edge. In addition to test the effects of empirical/hybrid Green's functions and with/without rupture front constraints on the inverted solutions, we will discuss distributions of slip-velocity intensity and a progression of wave generation with increasing frequency.

  1. Improved real-time dynamics from imaginary frequency lattice simulations

    NASA Astrophysics Data System (ADS)

    Pawlowski, Jan M.; Rothkopf, Alexander

    2018-03-01

    The computation of real-time properties, such as transport coefficients or bound state spectra of strongly interacting quantum fields in thermal equilibrium is a pressing matter. Since the sign problem prevents a direct evaluation of these quantities, lattice data needs to be analytically continued from the Euclidean domain of the simulation to Minkowski time, in general an ill-posed inverse problem. Here we report on a novel approach to improve the determination of real-time information in the form of spectral functions by setting up a simulation prescription in imaginary frequencies. By carefully distinguishing between initial conditions and quantum dynamics one obtains access to correlation functions also outside the conventional Matsubara frequencies. In particular the range between ω0 and ω1 = 2πT, which is most relevant for the inverse problem may be more highly resolved. In combination with the fact that in imaginary frequencies the kernel of the inverse problem is not an exponential but only a rational function we observe significant improvements in the reconstruction of spectral functions, demonstrated in a simple 0+1 dimensional scalar field theory toy model.

  2. Efficient Inversion of Mult-frequency and Multi-Source Electromagnetic Data

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gary D. Egbert

    2007-03-22

    The project covered by this report focused on development of efficient but robust non-linear inversion algorithms for electromagnetic induction data, in particular for data collected with multiple receivers, and multiple transmitters, a situation extremely common in eophysical EM subsurface imaging methods. A key observation is that for such multi-transmitter problems each step in commonly used linearized iterative limited memory search schemes such as conjugate gradients (CG) requires solution of forward and adjoint EM problems for each of the N frequencies or sources, essentially generating data sensitivities for an N dimensional data-subspace. These multiple sensitivities allow a good approximation to themore » full Jacobian of the data mapping to be built up in many fewer search steps than would be required by application of textbook optimization methods, which take no account of the multiplicity of forward problems that must be solved for each search step. We have applied this idea to a develop a hybrid inversion scheme that combines features of the iterative limited memory type methods with a Newton-type approach using a partial calculation of the Jacobian. Initial tests on 2D problems show that the new approach produces results essentially identical to a Newton type Occam minimum structure inversion, while running more rapidly than an iterative (fixed regularization parameter) CG style inversion. Memory requirements, while greater than for something like CG, are modest enough that even in 3D the scheme should allow 3D inverse problems to be solved on a common desktop PC, at least for modest (~ 100 sites, 15-20 frequencies) data sets. A secondary focus of the research has been development of a modular system for EM inversion, using an object oriented approach. This system has proven useful for more rapid prototyping of inversion algorithms, in particular allowing initial development and testing to be conducted with two-dimensional example problems, before approaching more computationally cumbersome three-dimensional problems.« less

  3. A frozen Gaussian approximation-based multi-level particle swarm optimization for seismic inversion

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Li, Jinglai, E-mail: jinglaili@sjtu.edu.cn; Lin, Guang, E-mail: lin491@purdue.edu; Computational Sciences and Mathematics Division, Pacific Northwest National Laboratory, Richland, WA 99352

    2015-09-01

    In this paper, we propose a frozen Gaussian approximation (FGA)-based multi-level particle swarm optimization (MLPSO) method for seismic inversion of high-frequency wave data. The method addresses two challenges in it: First, the optimization problem is highly non-convex, which makes hard for gradient-based methods to reach global minima. This is tackled by MLPSO which can escape from undesired local minima. Second, the character of high-frequency of seismic waves requires a large number of grid points in direct computational methods, and thus renders an extremely high computational demand on the simulation of each sample in MLPSO. We overcome this difficulty by threemore » steps: First, we use FGA to compute high-frequency wave propagation based on asymptotic analysis on phase plane; Then we design a constrained full waveform inversion problem to prevent the optimization search getting into regions of velocity where FGA is not accurate; Last, we solve the constrained optimization problem by MLPSO that employs FGA solvers with different fidelity. The performance of the proposed method is demonstrated by a two-dimensional full-waveform inversion example of the smoothed Marmousi model.« less

  4. Alzheimer's disease: the amyloid hypothesis and the Inverse Warburg effect

    PubMed Central

    Demetrius, Lloyd A.; Magistretti, Pierre J.; Pellerin, Luc

    2014-01-01

    Epidemiological and biochemical studies show that the sporadic forms of Alzheimer's disease (AD) are characterized by the following hallmarks: (a) An exponential increase with age; (b) Selective neuronal vulnerability; (c) Inverse cancer comorbidity. The present article appeals to these hallmarks to evaluate and contrast two competing models of AD: the amyloid hypothesis (a neuron-centric mechanism) and the Inverse Warburg hypothesis (a neuron-astrocytic mechanism). We show that these three hallmarks of AD conflict with the amyloid hypothesis, but are consistent with the Inverse Warburg hypothesis, a bioenergetic model which postulates that AD is the result of a cascade of three events—mitochondrial dysregulation, metabolic reprogramming (the Inverse Warburg effect), and natural selection. We also provide an explanation for the failures of the clinical trials based on amyloid immunization, and we propose a new class of therapeutic strategies consistent with the neuroenergetic selection model. PMID:25642192

  5. Identification of dynamic characteristics of flexible rotors as dynamic inverse problem

    NASA Technical Reports Server (NTRS)

    Roisman, W. P.; Vajingortin, L. D.

    1991-01-01

    The problem of dynamic and balancing of flexible rotors were considered, which were set and solved as the problem of the identification of flexible rotor systems, which is the same as the inverse problem of the oscillation theory dealing with the task of the identifying the outside influences and system parameters on the basis of the known laws of motion. This approach to the problem allows the disclosure the picture of disbalances throughout the rotor-under-test (which traditional methods of flexible rotor balancing, based on natural oscillations, could not provide), and identify dynamic characteristics of the system, which correspond to a selected mathematical model. Eventually, various methods of balancing were developed depending on the special features of the machines as to their design, technology, and operation specifications. Also, theoretical and practical methods are given for the flexible rotor balancing at far from critical rotation frequencies, which does not necessarily require the knowledge forms of oscillation, dissipation, and elasticity and inertia characteristics, and to use testing masses.

  6. Waveform inversion in the frequency domain for the simultaneous determination of earthquake source mechanism and moment function

    NASA Astrophysics Data System (ADS)

    Nakano, M.; Kumagai, H.; Inoue, H.

    2008-06-01

    We propose a method of waveform inversion to rapidly and routinely estimate both the moment function and the centroid moment tensor (CMT) of an earthquake. In this method, waveform inversion is carried out in the frequency domain to obtain the moment function more rapidly than when solved in the time domain. We assume a pure double-couple source mechanism in order to stabilize the solution when using data from a small number of seismic stations. The fault and slip orientations are estimated by a grid search with respect to the strike, dip and rake angles. The moment function in the time domain is obtained from the inverse Fourier transform of the frequency components determined by the inversion. Since observed waveforms used for the inversion are limited in a particular frequency band, the estimated moment function is a bandpassed form. We develop a practical approach to estimate the deconvolved form of the moment function, from which we can reconstruct detailed rupture history and the seismic moment. The source location is determined by a spatial grid search using adaptive grid spacings, which are gradually decreased in each step of the search. We apply this method to two events that occurred in Indonesia by using data from a broad-band seismic network in Indonesia (JISNET): one northeast of Sulawesi (Mw = 7.5) on 2007 January 21, and the other south of Java (Mw = 7.5) on 2006 July 17. The source centroid locations and mechanisms we estimated for both events are consistent with those determined by the Global CMT Project and the National Earthquake Information Center of the U.S. Geological Survey. The estimated rupture duration of the Sulawesi event is 16 s, which is comparable to a typical duration for earthquakes of this magnitude, while that of the Java event is anomalously long (176 s), suggesting that this event was a tsunami earthquake. Our application demonstrates that this inversion method has great potential for rapid and routine estimations of both the CMT and the moment function, and may be useful for identification of tsunami earthquakes.

  7. The source mechanisms of low frequency events in volcanoes - a comparison of synthetic and real seismic data on Soufriere Hills Volcano, Montserrat

    NASA Astrophysics Data System (ADS)

    Karl, S.; Neuberg, J. W.

    2012-04-01

    Low frequency seismic signals are one class of volcano seismic earthquakes that have been observed at many volcanoes around the world, and are thought to be associated with resonating fluid-filled conduits or fluid movements. Amongst others, Neuberg et al. (2006) proposed a conceptual model for the trigger of low frequency events at Montserrat involving the brittle failure of magma in the glass transition in response to high shear stresses during the upwards movement of magma in the volcanic edifice. For this study, synthetic seismograms were generated following the proposed concept of Neuberg et al. (2006) by using an extended source modelled as an octagonal arrangement of double couples approximating a circular ringfault. For comparison, synthetic seismograms were generated using single forces only. For both scenarios, synthetic seismograms were generated using a seismic station distribution as encountered on Soufriere Hills Volcano, Montserrat. To gain a better quantitative understanding of the driving forces of low frequency events, inversions for the physical source mechanisms have become increasingly common. Therefore, we perform moment tensor inversions (Dreger, 2003) using the synthetic data as well as a chosen set of seismograms recorded on Soufriere Hills Volcano. The inversions are carried out under the (wrong) assumption to have an underlying point source rather than an extended source as the trigger mechanism of the low frequency seismic events. We will discuss differences between inversion results, and how to interpret the moment tensor components (double couple, isotropic, or CLVD), which were based on a point source, in terms of an extended source.

  8. Eating frequency and overweight and obesity in children and adolescents: a meta-analysis.

    PubMed

    Kaisari, Panagiota; Yannakoulia, Mary; Panagiotakos, Demosthenes B

    2013-05-01

    To determine the effect of eating frequency on body weight status in children and adolescents. In this meta-analysis, original observational studies published to October 2011 were selected through a literature search in the PubMed database. The reference list of the retrieved articles was also used to identify relevant articles; researchers were contacted when needed. Selected studies were published in English, and they reported on the effect of eating frequency on overweight/obesity in children and adolescents. Pooled effect sizes were calculated using a random effects model. Ten cross-sectional studies and 1 case-control study (21 substudies in total), comprising 18 849 participants (aged 2-19 years), were included in the analysis. Their combined effect revealed that the highest category of eating frequency, as compared with the lowest, was associated with a beneficial effect regarding body weight status in children and adolescents (odds ratio [OR] = 0.78, log OR = -0.24, 95% confidence interval [CI] -0.41 to -0.06). The observed beneficial effect remained significant in boys (OR = 0.76, log OR = -0.27, 95% CI -0.47 to -0.06), but not in girls (OR = 0.96, log OR = -0.04, 95% CI -0.40 to 0.32) (P for sex differences = 0.14). Higher eating frequency was associated with lower body weight status in children and adolescents, mainly in boys. Clinical trials are warranted to confirm this inverse association, evaluate its clinical applicability, and support a public health recommendation; more studies are also needed to further investigate any sex-related differences, and most importantly, the biological mechanisms.

  9. A multi-frequency inverse-phase error compensation method for projector nonlinear in 3D shape measurement

    NASA Astrophysics Data System (ADS)

    Mao, Cuili; Lu, Rongsheng; Liu, Zhijian

    2018-07-01

    In fringe projection profilometry, the phase errors caused by the nonlinear intensity response of digital projectors needs to be correctly compensated. In this paper, a multi-frequency inverse-phase method is proposed. The theoretical model of periodical phase errors is analyzed. The periodical phase errors can be adaptively compensated in the wrapped maps by using a set of fringe patterns. The compensated phase is then unwrapped with multi-frequency method. Compared with conventional methods, the proposed method can greatly reduce the periodical phase error without calibrating measurement system. Some simulation and experimental results are presented to demonstrate the validity of the proposed approach.

  10. Determination of the rCBF in the Amygdala and Rhinal Cortex Using a FAIR-TrueFISP Sequence

    PubMed Central

    Martirosian, Petros; Klose, Uwe; Nägele, Thomas; Schick, Fritz; Ernemann, Ulrike

    2011-01-01

    Objective Brain perfusion can be assessed non-invasively by modern arterial spin labeling MRI. The FAIR (flow-sensitive alternating inversion recovery)-TrueFISP (true fast imaging in steady precession) technique was applied for regional assessment of cerebral blood flow in brain areas close to the skull base, since this approach provides low sensitivity to magnetic susceptibility effects. The investigation of the rhinal cortex and the amygdala is a potentially important feature for the diagnosis and research on dementia in its early stages. Materials and Methods Twenty-three subjects with no structural or psychological impairment were investigated. FAIR-True-FISP quantitative perfusion data were evaluated in the amygdala on both sides and in the pons. A preparation of the radiofrequency FOCI (frequency offset corrected inversion) pulse was used for slice selective inversion. After a time delay of 1.2 sec, data acquisition began. Imaging slice thickness was 5 mm and inversion slab thickness for slice selective inversion was 12.5 mm. Image matrix size for perfusion images was 64 × 64 with a field of view of 256 × 256 mm, resulting in a spatial resolution of 4 × 4 × 5 mm. Repetition time was 4.8 ms; echo time was 2.4 ms. Acquisition time for the 50 sets of FAIR images was 6:56 min. Data were compared with perfusion data from the literature. Results Perfusion values in the right amygdala, left amygdala and pons were 65.2 (± 18.2) mL/100 g/minute, 64.6 (± 21.0) mL/100 g/minute, and 74.4 (± 19.3) mL/100 g/minute, respectively. These values were higher than formerly published data using continuous arterial spin labeling but similar to 15O-PET (oxygen-15 positron emission tomography) data. Conclusion The FAIR-TrueFISP approach is feasible for the quantitative assessment of perfusion in the amygdala. Data are comparable with formerly published data from the literature. The applied technique provided excellent image quality, even for brain regions located at the skull base in the vicinity of marked susceptibility steps. PMID:21927556

  11. Fault Tolerant Signal Processing Using Finite Fields and Error-Correcting Codes.

    DTIC Science & Technology

    1983-06-01

    Decimation in Frequency Form, Fast Inverse Transform F-18 F-4 Part of Decimation in Time Form, Fast Inverse Transform F-21 I . LIST OF TABLES fable Title Page...F-2 Intermediate Variables In A Fast Inverse Transform F-14 Accession For NTIS GRA&il DTIC TAB E Unannounced El ** Dist ribut ion/ ____ AvailabilitY...component polynomials may be transformed to an equiva- lent series of multiplications of the related transform ’.. coefficients. The inverse transform of

  12. Temporal Variability of the Trade Wind Inversion: Measured with a Boundary Layer Vertical Profiler

    DTIC Science & Technology

    1992-05-01

    direction change . Consequently, the frequency of vertical observations is every 70 s and each measu t is a 30 s average. T. Riddle combined the raw data set... changes to superadiabatic. There is no change to the temperature at the inversion top. 25 Temperature ( and Dewpoint (-): 8 Aug. 1200 UTC 5000 4500 ! 4000...inversion base is the last level before the lapse rate changes to superadiaatc, (2) There is no change to temperature at the inversion top, and (3) A

  13. Estimation of elastic moduli in a compressible Gibson half-space by inverting Rayleigh-wave phase velocity

    USGS Publications Warehouse

    Xia, J.; Xu, Y.; Miller, R.D.; Chen, C.

    2006-01-01

    A Gibson half-space model (a non-layered Earth model) has the shear modulus varying linearly with depth in an inhomogeneous elastic half-space. In a half-space of sedimentary granular soil under a geostatic state of initial stress, the density and the Poisson's ratio do not vary considerably with depth. In such an Earth body, the dynamic shear modulus is the parameter that mainly affects the dispersion of propagating waves. We have estimated shear-wave velocities in the compressible Gibson half-space by inverting Rayleigh-wave phase velocities. An analytical dispersion law of Rayleigh-type waves in a compressible Gibson half-space is given in an algebraic form, which makes our inversion process extremely simple and fast. The convergence of the weighted damping solution is guaranteed through selection of the damping factor using the Levenberg-Marquardt method. Calculation efficiency is achieved by reconstructing a weighted damping solution using singular value decomposition techniques. The main advantage of this algorithm is that only three parameters define the compressible Gibson half-space model. Theoretically, to determine the model by the inversion, only three Rayleigh-wave phase velocities at different frequencies are required. This is useful in practice where Rayleigh-wave energy is only developed in a limited frequency range or at certain frequencies as data acquired at manmade structures such as dams and levees. Two real examples are presented and verified by borehole S-wave velocity measurements. The results of these real examples are also compared with the results of the layered-Earth model. ?? Springer 2006.

  14. Moment tensor inversion of tremor events at Arenal Volcano (Costa Rica)

    NASA Astrophysics Data System (ADS)

    Davi, Rosalia; O'Brien, Gareth; Lokmer, Ivan; Bean, Christopher; Lesage, Philippe; de Barros, Louis

    2010-05-01

    Arenal is a small, andesitic stratovolcano located in north-western Costa Rica, 97 km from the capital San Josè. Arenal's explosive activity is preceded, and accompanied, by different types of seismic events such as long period events, explosions, tremor and sporadic tectonic swarms. Tremor is the most common type of event recorded at Arenal with durations of up to several hours. Both spasmodic (1-6 Hz) and harmonic (0.9-2 Hz) tremor are observed with no clear difference in the genesis of each; the former can progressively evolve into the latter and vice-versa. However, the origin of the tremor is, at present, not fully understood. In order to retrieve the source mechanism generating these types of events, a moment tensor inversion is performed. A dataset recorded on the volcano, during a seismic experiment carried out in 2005, is used for the inversion. This dataset consists of ten days of data, from which two main groups of tremor at different frequencies (group one at 0.8-1.5 Hz and group two at 1.8-2.5 Hz) have been selected. A major difficulty in any inversion of tremor is that a clear onset can rarely be determined and hence retrieving the direct arrivals from the source is impossible. Usually, these arrivals are heavily contaminated by scattered waves. On Arenal the initial part of the tremor bands can be isolated, therefore offering a good opportunity to invert tremor for the source mechanism. The Green's functions used in the inversion were calculated using 3D numerical simulations including the real topography of the volcano and the best estimation of the velocity model available for Arenal. This velocity model was retrieved from seismic refraction experiments and sounding using the SPAC method. For each day, different tremor starting bands have been selected and divided into the groups mentioned above. For each band a source location is determined by performing a grid search through a volume of 4735 possible source points located under the crater summit. From the evaluation of the misfit values, a common source location is determined. The source appears to be located in shallow position, (less than 200 meters deep) under the crater summit. The source mechanisms for each tremor bands are retrieved for each day using the inversion procedure.

  15. Evaluation of brightness temperature from a forward model of ground-based microwave radiometer

    NASA Astrophysics Data System (ADS)

    Rambabu, S.; Pillai, J. S.; Agarwal, A.; Pandithurai, G.

    2014-06-01

    Ground-based microwave radiometers are getting great attention in recent years due to their capability to profile the temperature and humidity at high temporal and vertical resolution in the lower troposphere. The process of retrieving these parameters from the measurements of radiometric brightness temperature ( T B ) includes the inversion algorithm, which uses the back ground information from a forward model. In the present study, an algorithm development and evaluation of this forward model for a ground-based microwave radiometer, being developed by Society for Applied Microwave Electronics Engineering and Research (SAMEER) of India, is presented. Initially, the analysis of absorption coefficient and weighting function at different frequencies was made to select the channels. Further the range of variation of T B for these selected channels for the year 2011, over the two stations Mumbai and Delhi is discussed. Finally the comparison between forward-model simulated T B s and radiometer measured T B s at Mahabaleshwar (73.66 ∘E and 17.93∘N) is done to evaluate the model. There is good agreement between model simulations and radiometer observations, which suggests that these forward model simulations can be used as background for inversion models for retrieving the temperature and humidity profiles.

  16. Simultaneous Planck, Swift, and Fermi Observations of X-Ray and gamma-Ray Selected Blazars

    NASA Technical Reports Server (NTRS)

    Giommi, P.; Polenta, G.; Laehteenmaeki, A.; Thompson, D. J.; Capalbi, M.; Cutini, S.; Gasparrini, D.; Gonzalez-Nuevo, J.; Leon-Tavares, J.; Lopez-Caniego, M.; hide

    2011-01-01

    We present simultaneous Planck, Swift, Fermi, and ground-based data for 105 blazars belonging to three samples with flux limits in the soft X-ray, hard X-ray, and -ray bands, and we compare our results to those of a companion paper presenting simultaneous Planck and multi-frequency observations of 104 radio-loud northern active galactic nuclei selected at radio frequencies. While we confirm several previous results, our unique data set has allowed us to demonstrate that the selection method strongly influences the results, producing biases that cannot be ignored. Almost all the BL Lac objects have been detected by Fermi Large Area Telescope (LAT), whereas 30 to 40% of the flat-spectrum radio quasars (FSRQs) in the radio, soft X-ray, and hard X-ray selected samples are still below the gamma ray detection limit even after integrating 27 months of Fermi-LAT data. The radio to sub-millimetre spectral slope of blazars is quite flat, with [alpha] approximately 0 up to about 70 GHz, above which it steepens to [alpha] approximately -0.65. BL Lacs have significantly flatter spectra than FSRQs at higher frequencies. The distribution of the rest-frame synchrotron peak frequency (v(sup IC) (sub (PEAK)), ranges from 10(sup 21) to 10(sup 22) HZ. The distribution of the rest-frame synchrotron peak frequency (v(sup s)(sub peak)) in the spectral energy distribution (SED) of FSRQs is the same in all the blazar samples with (v(sup s)(sub peak) = 10(sup 13:1 plus or minus 0.1) Hz, while the mean inverse-Compton peak frequency,(v(sup IC)(sub peak) ranges from 10(sup 21) to 10(sup 22) Hz. The distributions of v(sup S)(sub peak) and of v(sup IC)(sub peak) of BL Lacs are much broader and are shifted to higher energies than those of FSRQs; their shapes strongly depend on the selection method. The Compton dominance of blazars ranges from less than 0.2 to nearly 100, with only FSRQs reaching values larger than about 3. Its distribution is broad and depends strongly on the selection method, with gamma-ray selected blazars peaking at approximately 7 or more, and radio-selected blazars at values close to 1, thus implying that the common assumption that the blazar power budget is largely dominated by high-energy emission is a selection effect. A comparison of our multi-frequency data with theoretical predictions shows that simple homogeneous SSC models cannot explain the simultaneous SEDs of most of the gamma-ray detected blazars in all samples. The SED of the blazars that were not detected by Fermi-LAT may instead be consistent with SSC emission. Our data challenge the correlation between bolometric luminosity and v(sup S)(sub peak) predicted by the blazar sequence.

  17. Solving the multi-frequency electromagnetic inverse source problem by the Fourier method

    NASA Astrophysics Data System (ADS)

    Wang, Guan; Ma, Fuming; Guo, Yukun; Li, Jingzhi

    2018-07-01

    This work is concerned with an inverse problem of identifying the current source distribution of the time-harmonic Maxwell's equations from multi-frequency measurements. Motivated by the Fourier method for the scalar Helmholtz equation and the polarization vector decomposition, we propose a novel method for determining the source function in the full vector Maxwell's system. Rigorous mathematical justifications of the method are given and numerical examples are provided to demonstrate the feasibility and effectiveness of the method.

  18. Three-dimensional imaging of buried objects in very lossy earth by inversion of VETEM data

    USGS Publications Warehouse

    Cui, T.J.; Aydiner, A.A.; Chew, W.C.; Wright, D.L.; Smith, D.V.

    2003-01-01

    The very early time electromagnetic system (VETEM) is an efficient tool for the detection of buried objects in very lossy earth, which allows a deeper penetration depth compared to the ground-penetrating radar. In this paper, the inversion of VETEM data is investigated using three-dimensional (3-D) inverse scattering techniques, where multiple frequencies are applied in the frequency range from 0-5 MHz. For small and moderately sized problems, the Born approximation and/or the Born iterative method have been used with the aid of the singular value decomposition and/or the conjugate gradient method in solving the linearized integral equations. For large-scale problems, a localized 3-D inversion method based on the Born approximation has been proposed for the inversion of VETEM data over a large measurement domain. Ways to process and to calibrate the experimental VETEM data are discussed to capture the real physics of buried objects. Reconstruction examples using synthesized VETEM data and real-world VETEM data are given to test the validity and efficiency of the proposed approach.

  19. Non-Random Inversion Landscapes in Prokaryotic Genomes Are Shaped by Heterogeneous Selection Pressures

    PubMed Central

    Repar, Jelena; Warnecke, Tobias

    2017-01-01

    Abstract Inversions are a major contributor to structural genome evolution in prokaryotes. Here, using a novel alignment-based method, we systematically compare 1,651 bacterial and 98 archaeal genomes to show that inversion landscapes are frequently biased toward (symmetric) inversions around the origin–terminus axis. However, symmetric inversion bias is not a universal feature of prokaryotic genome evolution but varies considerably across clades. At the extremes, inversion landscapes in Bacillus–Clostridium and Actinobacteria are dominated by symmetric inversions, while there is little or no systematic bias favoring symmetric rearrangements in archaea with a single origin of replication. Within clades, we find strong but clade-specific relationships between symmetric inversion bias and different features of adaptive genome architecture, including the distance of essential genes to the origin of replication and the preferential localization of genes on the leading strand. We suggest that heterogeneous selection pressures have converged to produce similar patterns of structural genome evolution across prokaryotes. PMID:28407093

  20. Quantification of thickness loss in a liquid-loaded plate using ultrasonic guided wave tomography

    NASA Astrophysics Data System (ADS)

    Rao, Jing; Ratassepp, Madis; Fan, Zheng

    2017-12-01

    Ultrasonic guided wave tomography (GWT) provides an attractive solution to map thickness changes from remote locations. It is based on the velocity-to-thickness mapping employing the dispersive characteristics of selected guided modes. This study extends the application of GWT on a liquid-loaded plate. It is a more challenging case than the application on a free plate, due to energy of the guided waves leaking into the liquid. In order to ensure the accuracy of thickness reconstruction, advanced forward models are developed to consider attenuation effects using complex velocities. The reconstruction of the thickness map is based on the frequency-domain full waveform inversion (FWI) method, and its accuracy is discussed using different frequencies and defect dimensions. Validation experiments are carried out on a water-loaded plate with an irregularly shaped defect using S0 guided waves, showing excellent performance of the reconstruction algorithm.

  1. Eye-Safe KGd(WO4)2:Nd Laser: Nano- and Subnanosecond Pulse Generation in Self-Frequency Raman Conversion Mode with Active Q-Switching

    NASA Astrophysics Data System (ADS)

    Dashkevich, V. I.; Orlovich, V. A.

    2017-03-01

    The shape of the multimode Stokes pulse generated by an eye-safe KGd(WO4)2:Nd laser with self-frequency Raman conversion and active Q-switching was shown to depend on the inhomogeneity of the active-medium pump. The laser generated a short and undistorted Stokes pulse of length 2.5 ns that increased with increasing laser cavity length for a moderately inhomogeneous pump characterized by a higher population inversion in the center of the active element. The energy of the Stokes pulse ( 11.5 mJ) varied little as the output-mirror reflectivity varied in the range 5-45%. The Raman pulse became distorted if the inhomogeneity of the pump was increased considerably. The degree of pump inhomogeneity was negligible with fundamental TEM00 mode selection. The laser generated subnanosecond Stokes pulses with peak power in the MW range.

  2. A developed nearly analytic discrete method for forward modeling in the frequency domain

    NASA Astrophysics Data System (ADS)

    Liu, Shaolin; Lang, Chao; Yang, Hui; Wang, Wenshuai

    2018-02-01

    High-efficiency forward modeling methods play a fundamental role in full waveform inversion (FWI). In this paper, the developed nearly analytic discrete (DNAD) method is proposed to accelerate frequency-domain forward modeling processes. We first derive the discretization of frequency-domain wave equations via numerical schemes based on the nearly analytic discrete (NAD) method to obtain a linear system. The coefficients of numerical stencils are optimized to make the linear system easier to solve and to minimize computing time. Wavefield simulation and numerical dispersion analysis are performed to compare the numerical behavior of DNAD method with that of the conventional NAD method. The results demonstrate the superiority of our proposed method. Finally, the DNAD method is implemented in frequency-domain FWI, and high-resolution inverse results are obtained.

  3. Compensation of nonlinearity in a fiber-optic transmission system using frequency-degenerate phase conjugation through counter-propagating dual pump FWM in a semiconductor optical amplifier

    NASA Astrophysics Data System (ADS)

    Anchal, Abhishek; K, Pradeep Kumar; O'Duill, Sean; Anandarajah, Prince M.; Landais, Pascal

    2018-04-01

    We present a scheme of frequency-degenerate mid-span spectral inversion (MSSI) for nonlinearity compensation in fiber-optic transmission systems. The spectral inversion is obtained by using counter-propagating dual pump four-wave mixing in a semiconductor optical amplifier (SOA). Frequency-degeneracy between signal and conjugate is achieved by keeping two pump frequencies symmetrical about the signal frequency. We simulate the performance of MSSI for nonlinearity compensation by scrutinizing the improvement of the Q-factor of a 200 Gbps QPSK signal transmitted over a standard single mode fiber, as a function of launch power for different span lengths and number of spans. We demonstrate a 7.5 dB improvement in the input power dynamic range and an almost 83% increase in the transmission length for optimum MSSI parameters of -2 dBm pump power and 400 mA SOA current.

  4. Building a good initial model for full-waveform inversion using frequency shift filter

    NASA Astrophysics Data System (ADS)

    Wang, Guanchao; Wang, Shangxu; Yuan, Sanyi; Lian, Shijie

    2018-05-01

    Accurate initial model or available low-frequency data is an important factor in the success of full waveform inversion (FWI). The low-frequency helps determine the kinematical relevant components, low-wavenumber of the velocity model, which are in turn needed to avoid FWI trap in local minima or cycle-skipping. However, in the field, acquiring data that <5 Hz is a challenging and expensive task. We attempt to find the common point of low- and high-frequency signal, then utilize the high-frequency data to obtain the low-wavenumber velocity model. It is well known that the instantaneous amplitude envelope of a wavelet is invariant under frequency shift. This means that resolution is constant for a given frequency bandwidth, and independent of the actual values of the frequencies. Based on this property, we develop a frequency shift filter (FSF) to build the relationship between low- and high-frequency information with a constant frequency bandwidth. After that, we can use the high-frequency information to get a plausible recovery of the low-wavenumber velocity model. Numerical results using synthetic data from the Marmousi and layer model demonstrate that our proposed envelope misfit function based on the frequency shift filter can build an initial model with more accurate long-wavelength components, when low-frequency signals are absent in recorded data.

  5. Performance analysis of a finite radon transform in OFDM system under different channel models

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dawood, Sameer A.; Anuar, M. S.; Fayadh, Rashid A.

    In this paper, a class of discrete Radon transforms namely Finite Radon Transform (FRAT) was proposed as a modulation technique in the realization of Orthogonal Frequency Division Multiplexing (OFDM). The proposed FRAT operates as a data mapper in the OFDM transceiver instead of the conventional phase shift mapping and quadrature amplitude mapping that are usually used with the standard OFDM based on Fast Fourier Transform (FFT), by the way that ensure increasing the orthogonality of the system. The Fourier domain approach was found here to be the more suitable way for obtaining the forward and inverse FRAT. This structure resultedmore » in a more suitable realization of conventional FFT- OFDM. It was shown that this application increases the orthogonality significantly in this case due to the use of Inverse Fast Fourier Transform (IFFT) twice, namely, in the data mapping and in the sub-carrier modulation also due to the use of an efficient algorithm in determining the FRAT coefficients called the optimal ordering method. The proposed approach was tested and compared with conventional OFDM, for additive white Gaussian noise (AWGN) channel, flat fading channel, and multi-path frequency selective fading channel. The obtained results showed that the proposed system has improved the bit error rate (BER) performance by reducing inter-symbol interference (ISI) and inter-carrier interference (ICI), comparing with conventional OFDM system.« less

  6. Performance analysis of a finite radon transform in OFDM system under different channel models

    NASA Astrophysics Data System (ADS)

    Dawood, Sameer A.; Malek, F.; Anuar, M. S.; Fayadh, Rashid A.; Abdullah, Farrah Salwani

    2015-05-01

    In this paper, a class of discrete Radon transforms namely Finite Radon Transform (FRAT) was proposed as a modulation technique in the realization of Orthogonal Frequency Division Multiplexing (OFDM). The proposed FRAT operates as a data mapper in the OFDM transceiver instead of the conventional phase shift mapping and quadrature amplitude mapping that are usually used with the standard OFDM based on Fast Fourier Transform (FFT), by the way that ensure increasing the orthogonality of the system. The Fourier domain approach was found here to be the more suitable way for obtaining the forward and inverse FRAT. This structure resulted in a more suitable realization of conventional FFT- OFDM. It was shown that this application increases the orthogonality significantly in this case due to the use of Inverse Fast Fourier Transform (IFFT) twice, namely, in the data mapping and in the sub-carrier modulation also due to the use of an efficient algorithm in determining the FRAT coefficients called the optimal ordering method. The proposed approach was tested and compared with conventional OFDM, for additive white Gaussian noise (AWGN) channel, flat fading channel, and multi-path frequency selective fading channel. The obtained results showed that the proposed system has improved the bit error rate (BER) performance by reducing inter-symbol interference (ISI) and inter-carrier interference (ICI), comparing with conventional OFDM system.

  7. An objective rationale for the choice of regularisation parameter with application to global multiple-frequency S-wave tomography

    NASA Astrophysics Data System (ADS)

    Zaroli, C.; Sambridge, M.; Lévêque, J.-J.; Debayle, E.; Nolet, G.

    2013-06-01

    In a linear ill-posed inverse problem, the regularisation parameter (damping) controls the balance between minimising both the residual data misfit and the model norm. Poor knowledge of data uncertainties often makes the selection of damping rather arbitrary. To go beyond that subjectivity, an objective rationale for the choice of damping is presented, which is based on the coherency of delay-time estimates in different frequency bands. Our method is tailored to the problem of global Multiple-Frequency Tomography (MFT), using a data set of 287 078 S-wave delay-times measured in five frequency bands (10, 15, 22, 34, 51 s central periods). Whereas for each ray path the delay-time estimates should vary coherently from one period to the other, the noise most likely is not coherent. Thus, the lack of coherency of the information in different frequency bands is exploited, using an analogy with the cross-validation method, to identify models dominated by noise. In addition, a sharp change of behaviour of the model ℓ∞-norm, as the damping becomes lower than a threshold value, is interpreted as the signature of data noise starting to significantly pollute at least one model component. Models with damping larger than this threshold are diagnosed as being constructed with poor data exploitation. Finally, a preferred model is selected from the remaining range of permitted model solutions. This choice is quasi-objective in terms of model interpretation, as the selected model shows a high degree of similarity with almost all other permitted models (correlation superior to 98% up to spherical harmonic degree 80). The obtained tomographic model is displayed in mid lower-mantle (660-1910 km depth), and is shown to be compatible with three other recent global shear-velocity models. A wider application of the presented rationale should permit us to converge towards more objective seismic imaging of the Earth's mantle.

  8. An objective rationale for the choice of regularisation parameter with application to global multiple-frequency S-wave tomography

    NASA Astrophysics Data System (ADS)

    Zaroli, C.; Sambridge, M.; Lévêque, J.-J.; Debayle, E.; Nolet, G.

    2013-10-01

    In a linear ill-posed inverse problem, the regularisation parameter (damping) controls the balance between minimising both the residual data misfit and the model norm. Poor knowledge of data uncertainties often makes the selection of damping rather arbitrary. To go beyond that subjectivity, an objective rationale for the choice of damping is presented, which is based on the coherency of delay-time estimates in different frequency bands. Our method is tailored to the problem of global multiple-frequency tomography (MFT), using a data set of 287 078 S-wave delay times measured in five frequency bands (10, 15, 22, 34, and 51 s central periods). Whereas for each ray path the delay-time estimates should vary coherently from one period to the other, the noise most likely is not coherent. Thus, the lack of coherency of the information in different frequency bands is exploited, using an analogy with the cross-validation method, to identify models dominated by noise. In addition, a sharp change of behaviour of the model ℓ∞-norm, as the damping becomes lower than a threshold value, is interpreted as the signature of data noise starting to significantly pollute at least one model component. Models with damping larger than this threshold are diagnosed as being constructed with poor data exploitation. Finally, a preferred model is selected from the remaining range of permitted model solutions. This choice is quasi-objective in terms of model interpretation, as the selected model shows a high degree of similarity with almost all other permitted models (correlation superior to 98% up to spherical harmonic degree 80). The obtained tomographic model is displayed in the mid lower-mantle (660-1910 km depth), and is shown to be compatible with three other recent global shear-velocity models. A wider application of the presented rationale should permit us to converge towards more objective seismic imaging of Earth's mantle.

  9. Bowhead whale localization using asynchronous hydrophones in the Chukchi Sea.

    PubMed

    Warner, Graham A; Dosso, Stan E; Hannay, David E; Dettmer, Jan

    2016-07-01

    This paper estimates bowhead whale locations and uncertainties using non-linear Bayesian inversion of their modally-dispersed calls recorded on asynchronous recorders in the Chukchi Sea, Alaska. Bowhead calls were recorded on a cluster of 7 asynchronous ocean-bottom hydrophones that were separated by 0.5-9.2 km. A warping time-frequency analysis is used to extract relative mode arrival times as a function of frequency for nine frequency-modulated whale calls that dispersed in the shallow water environment. Each call was recorded on multiple hydrophones and the mode arrival times are inverted for: the whale location in the horizontal plane, source instantaneous frequency (IF), water sound-speed profile, seabed geoacoustic parameters, relative recorder clock drifts, and residual error standard deviations, all with estimated uncertainties. A simulation study shows that accurate prior environmental knowledge is not required for accurate localization as long as the inversion treats the environment as unknown. Joint inversion of multiple recorded calls is shown to substantially reduce uncertainties in location, source IF, and relative clock drift. Whale location uncertainties are estimated to be 30-160 m and relative clock drift uncertainties are 3-26 ms.

  10. Joint inversion of marine MT and CSEM data over Gemini prospect, Gulf of Mexico

    NASA Astrophysics Data System (ADS)

    Constable, S.; Orange, A. S.; Key, K.

    2013-12-01

    In 2003 we tested a prototype marine controlled-source electromagnetic (CSEM) transmitter over the Gemini salt body in the Gulf of Mexico, collecting one line of data over 15 seafloor receiver instruments using the Cox waveform with a 0.25 Hz fundamental, yielding 3 usable frequencies. Transmission current was 95 amps on a 150 m antenna. We had previously collected 16 sites of marine magnetotelluric (MT) data along this line during the development of broadband marine MT as a tool for mapping salt geometry. Recently we commissioned a finite element code capable of joint CSEM and MT 2D inversion incorporating bathymetry and anisotropy, and this heritage data set provided an opportunity to explore such inversions with real data. We reprocessed the CSEM data to obtain objective error estimates and inverted single frequency CSEM, multi-frequency CSEM, MT, and joint MT and CSEM data sets for a variety of target misfits, using the Occam regularized inversion algorithm. As expected, MT-only inversions produce a smoothed image of the salt and a resistive basement at 9 km depth. The CSEM data image a conductive cap over the salt body and have little sensitivity to the salt or structure at depths beyond about 1500 m below seafloor. However, the joint inversion yields more than the sum of the parts - the outline of the salt body is much sharper and there is much more structural detail even at depths beyond the resolution of the CSEM data. As usual, model complexity greatly depends on target misfit, and even with well-estimated errors the choice of misfit becomes a somewhat subjective decision. Our conclusion is a familiar one; more data are always good.

  11. Towards seismic waveform inversion of long-offset Ocean-Bottom Seismic data for deep crustal imaging offshore Western Australia

    NASA Astrophysics Data System (ADS)

    Monnier, S.; Lumley, D. E.; Kamei, R.; Goncharov, A.; Shragge, J. C.

    2016-12-01

    Ocean Bottom Seismic datasets have become increasingly used in recent years to develop high-resolution, wavelength-scale P-wave velocity models of the lithosphere from waveform inversion, due to their recording of long-offset transmitted phases. New OBS surveys evolve towards novel acquisition geometries involving longer offsets (several hundreds of km), broader frequency content (1-100 Hz), while receiver sampling often remains sparse (several km). Therefore, it is critical to assess the effects of such geometries on the eventual success and resolution of waveform inversion velocity models. In this study, we investigate the feasibility of waveform inversion on the Bart 2D OBS profile acquired offshore Western Australia, to investigate regional crustal and Moho structures. The dataset features 14 broadband seismometers (0.01-100 Hz) from AuScope's national OBS fleet, offsets in excess of 280 km, and a sparse receiver sampling (18 km). We perform our analysis in four stages: (1) field data analysis, (2) 2D P-wave velocity model building, synthetic data (3) modelling, and (4) waveform inversion. Data exploration shows high-quality active-source signal down to 2Hz, and usable first arrivals to offsets greater than 100 km. The background velocity model is constructed by combining crustal and Moho information in continental reference models (e.g., AuSREM, AusMoho). These low-resolution studies suggest a crustal thickness of 20-25 km along our seismic line and constitute a starting point for synthetic modelling and inversion. We perform synthetic 2D time-domain modelling to: (1) evaluate the misfit between synthetic and field data within the usable frequency band (2-10 Hz); (2) validate our velocity model; and (3) observe the effects of sparse OBS interval on data quality. Finally, we apply 2D acoustic frequency-domain waveform inversion to the synthetic data to generate velocity model updates. The inverted model is compared to the reference model to investigate the improved crustal resolution and Moho boundary delineation that could be realized using waveform inversion, and to evaluate the effects of the acquisition parameters. The inversion strategies developed through the synthetic tests will help the subsequent inversion of sparse, long-offset OBS field data.

  12. The Ellipticity Filter-A Proposed Solution to the Mixed Event Problem in Nuclear Seismic Discrimination

    DTIC Science & Technology

    1974-09-07

    ellipticity filter. The source waveforms are recreated by an inverse transform of those complex ampli- tudes associated with the same azimuth...terms of the three complex data points and the ellipticity. Having solved the equations for all frequency bins, the inverse transform of...Transform of those complex amplitudes associated with Source 1, yielding the signal a (t). Similarly, take the inverse Transform of all

  13. Inverts permittivity and conductivity with structural constraint in GPR FWI based on truncated Newton method

    NASA Astrophysics Data System (ADS)

    Ren, Qianci

    2018-04-01

    Full waveform inversion (FWI) of ground penetrating radar (GPR) is a promising technique to quantitatively evaluate the permittivity and conductivity of near subsurface. However, these two parameters are simultaneously inverted in the GPR FWI, increasing the difficulty to obtain accurate inversion results for both parameters. In this study, I present a structural constrained GPR FWI procedure to jointly invert the two parameters, aiming to force a structural relationship between permittivity and conductivity in the process of model reconstruction. The structural constraint is enforced by a cross-gradient function. In this procedure, the permittivity and conductivity models are inverted alternately at each iteration and updated with hierarchical frequency components in the frequency domain. The joint inverse problem is solved by the truncated Newton method which considering the effect of Hessian operator and using the approximated solution of Newton equation to be the perturbation model in the updating process. The joint inversion procedure is tested by three synthetic examples. The results show that jointly inverting permittivity and conductivity in GPR FWI effectively increases the structural similarities between the two parameters, corrects the structures of parameter models, and significantly improves the accuracy of conductivity model, resulting in a better inversion result than the individual inversion.

  14. Accommodating Chromosome Inversions in Linkage Analysis

    PubMed Central

    Chen, Gary K.; Slaten, Erin; Ophoff, Roel A.; Lange, Kenneth

    2006-01-01

    This work develops a population-genetics model for polymorphic chromosome inversions. The model precisely describes how an inversion changes the nature of and approach to linkage equilibrium. The work also describes algorithms and software for allele-frequency estimation and linkage analysis in the presence of an inversion. The linkage algorithms implemented in the software package Mendel estimate recombination parameters and calculate the posterior probability that each pedigree member carries the inversion. Application of Mendel to eight Centre d'Étude du Polymorphisme Humain pedigrees in a region containing a common inversion on 8p23 illustrates its potential for providing more-precise estimates of the location of an unmapped marker or trait gene. Our expanded cytogenetic analysis of these families further identifies inversion carriers and increases the evidence of linkage. PMID:16826515

  15. Sleep and Substance Use among US Adolescents, 1991-2014.

    PubMed

    Terry-McElrath, Yvonne M; Maslowsky, Julie; O'Malley, Patrick M; Schulenberg, John E; Johnston, Lloyd D

    2016-01-01

    To examine associations between sleep and alcohol, amphetamine, cigarette, marijuana, and non-heroin narcotic use among US middle and high school students, trends in associations over time, and the comparative impact of select covariates on association strength. Data from the 1991-2014 nationally representative Monitoring the Future study of 8(th)-, 10(th)-, and 12(th)-grade US students were used to estimate standardized correlations between the frequency of getting at least 7 hours of sleep (7+ sleep) and substance use frequency while simultaneously regressing both outcomes on key covariate domains. As 7+ sleep frequency increased, substance use frequency significantly decreased and vice versa. Overall, association strength was inversely associated with grade. Associations were generally modest, varied across substances, and weakened over the historical period examined for 8(th)- and 10(th)- graders. Associations showed little variance by sex and racial/ethnic subgroups. Controlling for deviance, psychosocial and general health covariates significantly attenuated association strength. Among US secondary students, 7+ sleep/substance use associations were largely explained by individual deviance, psychosocial, and general health characteristics. Awareness and exploitation of these shared associations may be useful in improving substance use prevention and/or treatment efforts.

  16. Model selection and Bayesian inference for high-resolution seabed reflection inversion.

    PubMed

    Dettmer, Jan; Dosso, Stan E; Holland, Charles W

    2009-02-01

    This paper applies Bayesian inference, including model selection and posterior parameter inference, to inversion of seabed reflection data to resolve sediment structure at a spatial scale below the pulse length of the acoustic source. A practical approach to model selection is used, employing the Bayesian information criterion to decide on the number of sediment layers needed to sufficiently fit the data while satisfying parsimony to avoid overparametrization. Posterior parameter inference is carried out using an efficient Metropolis-Hastings algorithm for high-dimensional models, and results are presented as marginal-probability depth distributions for sound velocity, density, and attenuation. The approach is applied to plane-wave reflection-coefficient inversion of single-bounce data collected on the Malta Plateau, Mediterranean Sea, which indicate complex fine structure close to the water-sediment interface. This fine structure is resolved in the geoacoustic inversion results in terms of four layers within the upper meter of sediments. The inversion results are in good agreement with parameter estimates from a gravity core taken at the experiment site.

  17. A 2D Electron Density and Plasma Current Density Diagnostic for Opening Switches

    DTIC Science & Technology

    2006-02-01

    x, y)) can be recovered by taking the inverse transform of C(f - f,, y), and calculating the inverse tangent of the ratio of its real and imaginary...parts, 27rfox + (x,y) = tan-1 [Re(IT)/Im(IT)], (7) where IT represents the inverse transform of C(f - fo, y). There are a number of options available...notch filtering around f, before the inverse transform is taken. However, since frequency space is discrete due to the discrete nature of the FFT, we

  18. Adaptive Role of Inversion Polymorphism of Drosophila subobscura in Lead Stressed Environment

    PubMed Central

    Kenig, Bojan; Kurbalija Novičić, Zorana; Patenković, Aleksandra; Stamenković-Radak, Marina; Anđelković, Marko

    2015-01-01

    Local adaptation to environmental stress at different levels of genetic polymorphism in various plants and animals has been documented through evolution of heavy metal tolerance. We used samples of Drosophila subobscura populations from two differently polluted environments to analyze the change of chromosomal inversion polymorphism as genetic marker during laboratory exposure to lead. Exposure to environmental contamination can affect the genetic content within a particular inversion and produce targets for selection in populations from different environments. The aims were to discover whether the inversion polymorphism is shaped by the local natural environments, and if lead as a selection pressure would cause adaptive divergence of two populations during the multigenerational laboratory experiment. The results showed that populations retain signatures from past contamination events, and that heavy metal pollution can cause adaptive changes in population. Differences in inversion polymorphism between the two populations increased over generations under lead contamination in the laboratory. The inversion polymorphism of population originating from the more polluted natural environment was more stable during the experiment, both under conditions with and without lead. Therefore, results showed that inversion polymorphism as a genetic marker reflects a strong signature of adaptation to the local environment, and that historical demographic events and selection are important for both prediction of evolutionary potential and long-term viability of natural populations. PMID:26102201

  19. Adaptive Role of Inversion Polymorphism of Drosophila subobscura in Lead Stressed Environment.

    PubMed

    Kenig, Bojan; Kurbalija Novičić, Zorana; Patenković, Aleksandra; Stamenković-Radak, Marina; Anđelković, Marko

    2015-01-01

    Local adaptation to environmental stress at different levels of genetic polymorphism in various plants and animals has been documented through evolution of heavy metal tolerance. We used samples of Drosophila subobscura populations from two differently polluted environments to analyze the change of chromosomal inversion polymorphism as genetic marker during laboratory exposure to lead. Exposure to environmental contamination can affect the genetic content within a particular inversion and produce targets for selection in populations from different environments. The aims were to discover whether the inversion polymorphism is shaped by the local natural environments, and if lead as a selection pressure would cause adaptive divergence of two populations during the multigenerational laboratory experiment. The results showed that populations retain signatures from past contamination events, and that heavy metal pollution can cause adaptive changes in population. Differences in inversion polymorphism between the two populations increased over generations under lead contamination in the laboratory. The inversion polymorphism of population originating from the more polluted natural environment was more stable during the experiment, both under conditions with and without lead. Therefore, results showed that inversion polymorphism as a genetic marker reflects a strong signature of adaptation to the local environment, and that historical demographic events and selection are important for both prediction of evolutionary potential and long-term viability of natural populations.

  20. Dynamic chirp control of all-optical format-converted pulsed data from a multi-wavelength inverse-optical-comb injected semiconductor optical amplifier.

    PubMed

    Lin, Gong-Ru; Pan, Ci-Ling; Yu, Kun-Chieh

    2007-10-01

    By spectrally and temporally reshaping the gain-window of a traveling-wave semiconductor optical amplifier (TWSOA) with a backward injected multi- or single-wavelength inverse-optical-comb, we theoretically and experimentally investigate the dynamic frequency chirp of the all-optical 10GBit/s Return-to-Zero (RZ) data-stream format-converted from the TWSOA under strong cross-gain depletion scheme. The multi-wavelength inverse-optical-comb injection effectively depletes the TWSOA gain spectrally and temporally, remaining a narrow gain-window and a reduced spectral linewidth and provide a converted RZ data with a smaller peak-to-peak frequency chirp of 6.7 GHz. Even at high inverse-optical-comb injection power and highly biased current condition for improving the operational bit-rate, the chirp of the multi-wavelength-injection converted RZ pulse is still 2.1-GHz smaller than that obtained by using single-wavelength injection at a cost of slight pulse-width broadening by 1 ps.

  1. Time-Lapse Acoustic Impedance Inversion in CO2 Sequestration Study (Weyburn Field, Canada)

    NASA Astrophysics Data System (ADS)

    Wang, Y.; Morozov, I. B.

    2016-12-01

    Acoustic-impedance (AI) pseudo-logs are useful for characterising subtle variations of fluid content during seismic monitoring of reservoirs undergoing enhanced oil recovery and/or geologic CO2 sequestration. However, highly accurate AI images are required for time-lapse analysis, which may be difficult to achieve with conventional inversion approaches. In this study, two enhancements of time-lapse AI analysis are proposed. First, a well-known uncertainty of AI inversion is caused by the lack of low-frequency signal in reflection seismic data. To resolve this difficulty, we utilize an integrated AI inversion approach combining seismic data, acoustic well logs and seismic-processing velocities. The use of well logs helps stabilizing the recursive AI inverse, and seismic-processing velocities are used to complement the low-frequency information in seismic records. To derive the low-frequency AI from seismic-processing velocity data, an empirical relation is determined by using the available acoustic logs. This method is simple and does not require subjective choices of parameters and regularization schemes as in the more sophisticated joint inversion methods. The second improvement to accurate time-lapse AI imaging consists in time-variant calibration of reflectivity. Calibration corrections consist of time shifts, amplitude corrections, spectral shaping and phase rotations. Following the calibration, average and differential reflection amplitudes are calculated, from which the average and differential AI are obtained. The approaches are applied to a time-lapse 3-D 3-C dataset from Weyburn CO2 sequestration project in southern Saskatchewan, Canada. High quality time-lapse AI volumes are obtained. Comparisons with traditional recursive and colored AI inversions (obtained without using seismic-processing velocities) show that the new method gives a better representation of spatial AI variations. Although only early stages of monitoring seismic data are available, time-lapse AI variations mapped within and near the reservoir zone suggest correlations with CO2 injection. By extending this procedure to elastic impedances, additional constraints on the variations of physical properties within the reservoir can be obtained.

  2. Local T1-T2 distribution measurements in porous media

    NASA Astrophysics Data System (ADS)

    Vashaee, S.; Li, M.; Newling, B.; MacMillan, B.; Marica, F.; Kwak, H. T.; Gao, J.; Al-harbi, A. M.; Balcom, B. J.

    2018-02-01

    A novel slice-selective T1-T2 measurement is proposed to measure spatially resolved T1-T2 distributions. An adiabatic inversion pulse is employed for slice-selection. The slice-selective pulse is able to select a quasi-rectangular slice, on the order of 1 mm, at an arbitrary position within the sample. The method does not employ conventional selective excitation in which selective excitation is often accomplished by rotation of the longitudinal magnetization in the slice of interest into the transverse plane, but rather a subtraction based on CPMG data acquired with and without adiabatic inversion slice selection. T1 weighting is introduced during recovery from the inversion associated with slice selection. The local T1-T2 distributions measured are of similar quality to bulk T1-T2 measurements. The new method can be employed to characterize oil-water mixtures and other fluids in porous media. The method is beneficial when a coarse spatial distribution of the components is of interest.

  3. Distance from sub-Saharan Africa predicts mutational load in diverse human genomes.

    PubMed

    Henn, Brenna M; Botigué, Laura R; Peischl, Stephan; Dupanloup, Isabelle; Lipatov, Mikhail; Maples, Brian K; Martin, Alicia R; Musharoff, Shaila; Cann, Howard; Snyder, Michael P; Excoffier, Laurent; Kidd, Jeffrey M; Bustamante, Carlos D

    2016-01-26

    The Out-of-Africa (OOA) dispersal ∼ 50,000 y ago is characterized by a series of founder events as modern humans expanded into multiple continents. Population genetics theory predicts an increase of mutational load in populations undergoing serial founder effects during range expansions. To test this hypothesis, we have sequenced full genomes and high-coverage exomes from seven geographically divergent human populations from Namibia, Congo, Algeria, Pakistan, Cambodia, Siberia, and Mexico. We find that individual genomes vary modestly in the overall number of predicted deleterious alleles. We show via spatially explicit simulations that the observed distribution of deleterious allele frequencies is consistent with the OOA dispersal, particularly under a model where deleterious mutations are recessive. We conclude that there is a strong signal of purifying selection at conserved genomic positions within Africa, but that many predicted deleterious mutations have evolved as if they were neutral during the expansion out of Africa. Under a model where selection is inversely related to dominance, we show that OOA populations are likely to have a higher mutation load due to increased allele frequencies of nearly neutral variants that are recessive or partially recessive.

  4. Infrared and visible image fusion scheme based on NSCT and low-level visual features

    NASA Astrophysics Data System (ADS)

    Li, Huafeng; Qiu, Hongmei; Yu, Zhengtao; Zhang, Yafei

    2016-05-01

    Multi-scale transform (MST) is an efficient tool for image fusion. Recently, many fusion methods have been developed based on different MSTs, and they have shown potential application in many fields. In this paper, we propose an effective infrared and visible image fusion scheme in nonsubsampled contourlet transform (NSCT) domain, in which the NSCT is firstly employed to decompose each of the source images into a series of high frequency subbands and one low frequency subband. To improve the fusion performance we designed two new activity measures for fusion of the lowpass subbands and the highpass subbands. These measures are developed based on the fact that the human visual system (HVS) percept the image quality mainly according to its some low-level features. Then, the selection principles of different subbands are presented based on the corresponding activity measures. Finally, the merged subbands are constructed according to the selection principles, and the final fused image is produced by applying the inverse NSCT on these merged subbands. Experimental results demonstrate the effectiveness and superiority of the proposed method over the state-of-the-art fusion methods in terms of both visual effect and objective evaluation results.

  5. Numerical solution of inverse scattering for near-field optics.

    PubMed

    Bao, Gang; Li, Peijun

    2007-06-01

    A novel regularized recursive linearization method is developed for a two-dimensional inverse medium scattering problem that arises in near-field optics, which reconstructs the scatterer of an inhomogeneous medium located on a substrate from data accessible through photon scanning tunneling microscopy experiments. Based on multiple frequency scattering data, the method starts from the Born approximation corresponding to weak scattering at a low frequency, and each update is obtained by continuation on the wavenumber from solutions of one forward problem and one adjoint problem of the Helmholtz equation.

  6. Effects of Conjugate Gradient Methods and Step-Length Formulas on the Multiscale Full Waveform Inversion in Time Domain: Numerical Experiments

    NASA Astrophysics Data System (ADS)

    Liu, Youshan; Teng, Jiwen; Xu, Tao; Badal, José; Liu, Qinya; Zhou, Bing

    2017-05-01

    We carry out full waveform inversion (FWI) in time domain based on an alternative frequency-band selection strategy that allows us to implement the method with success. This strategy aims at decomposing the seismic data within partially overlapped frequency intervals by carrying out a concatenated treatment of the wavelet to largely avoid redundant frequency information to adapt to wavelength or wavenumber coverage. A pertinent numerical test proves the effectiveness of this strategy. Based on this strategy, we comparatively analyze the effects of update parameters for the nonlinear conjugate gradient (CG) method and step-length formulas on the multiscale FWI through several numerical tests. The investigations of up to eight versions of the nonlinear CG method with and without Gaussian white noise make clear that the HS (Hestenes and Stiefel in J Res Natl Bur Stand Sect 5:409-436, 1952), CD (Fletcher in Practical methods of optimization vol. 1: unconstrained optimization, Wiley, New York, 1987), and PRP (Polak and Ribière in Revue Francaise Informat Recherche Opertionelle, 3e Année 16:35-43, 1969; Polyak in USSR Comput Math Math Phys 9:94-112, 1969) versions are more efficient among the eight versions, while the DY (Dai and Yuan in SIAM J Optim 10:177-182, 1999) version always yields inaccurate result, because it overestimates the deeper parts of the model. The application of FWI algorithms using distinct step-length formulas, such as the direct method ( Direct), the parabolic search method ( Search), and the two-point quadratic interpolation method ( Interp), proves that the Interp is more efficient for noise-free data, while the Direct is more efficient for Gaussian white noise data. In contrast, the Search is less efficient because of its slow convergence. In general, the three step-length formulas are robust or partly insensitive to Gaussian white noise and the complexity of the model. When the initial velocity model deviates far from the real model or the data are contaminated by noise, the objective function values of the Direct and Interp are oscillating at the beginning of the inversion, whereas that of the Search decreases consistently.

  7. Lipid suppression via double inversion recovery with symmetric frequency sweep for robust 2D‐GRAPPA‐accelerated MRSI of the brain at 7 T

    PubMed Central

    Hangel, Gilbert; Strasser, Bernhard; Považan, Michal; Gruber, Stephan; Chmelík, Marek; Gajdošík, Martin; Trattnig, Siegfried

    2015-01-01

    This work presents a new approach for high‐resolution MRSI of the brain at 7 T in clinically feasible measurement times. Two major problems of MRSI are the long scan times for large matrix sizes and the possible spectral contamination by the transcranial lipid signal. We propose a combination of free induction decay (FID)‐MRSI with a short acquisition delay and acceleration via in‐plane two‐dimensional generalised autocalibrating partially parallel acquisition (2D‐GRAPPA) with adiabatic double inversion recovery (IR)‐based lipid suppression to allow robust high‐resolution MRSI. We performed Bloch simulations to evaluate the magnetisation pathways of lipids and metabolites, and compared the results with phantom measurements. Acceleration factors in the range 2–25 were tested in a phantom. Five volunteers were scanned to verify the value of our MRSI method in vivo. GRAPPA artefacts that cause fold‐in of transcranial lipids were suppressed via double IR, with a non‐selective symmetric frequency sweep. The use of long, low‐power inversion pulses (100 ms) reduced specific absorption rate requirements. The symmetric frequency sweep over both pulses provided good lipid suppression (>90%), in addition to a reduced loss in metabolite signal‐to‐noise ratio (SNR), compared with conventional IR suppression (52–70%). The metabolic mapping over the whole brain slice was not limited to a rectangular region of interest. 2D‐GRAPPA provided acceleration up to a factor of nine for in vivo FID‐MRSI without a substantial increase in g‐factors (<1.1). A 64 × 64 matrix can be acquired with a common repetition time of ~1.3 s in only 8 min without lipid artefacts caused by acceleration. Overall, we present a fast and robust MRSI method, using combined double IR fat suppression and 2D‐GRAPPA acceleration, which may be used in (pre)clinical studies of the brain at 7 T. © 2015 The Authors. NMR in Biomedicine published by John Wiley & Sons Ltd. PMID:26370781

  8. Lipid suppression via double inversion recovery with symmetric frequency sweep for robust 2D-GRAPPA-accelerated MRSI of the brain at 7 T.

    PubMed

    Hangel, Gilbert; Strasser, Bernhard; Považan, Michal; Gruber, Stephan; Chmelík, Marek; Gajdošík, Martin; Trattnig, Siegfried; Bogner, Wolfgang

    2015-11-01

    This work presents a new approach for high-resolution MRSI of the brain at 7 T in clinically feasible measurement times. Two major problems of MRSI are the long scan times for large matrix sizes and the possible spectral contamination by the transcranial lipid signal. We propose a combination of free induction decay (FID)-MRSI with a short acquisition delay and acceleration via in-plane two-dimensional generalised autocalibrating partially parallel acquisition (2D-GRAPPA) with adiabatic double inversion recovery (IR)-based lipid suppression to allow robust high-resolution MRSI. We performed Bloch simulations to evaluate the magnetisation pathways of lipids and metabolites, and compared the results with phantom measurements. Acceleration factors in the range 2-25 were tested in a phantom. Five volunteers were scanned to verify the value of our MRSI method in vivo. GRAPPA artefacts that cause fold-in of transcranial lipids were suppressed via double IR, with a non-selective symmetric frequency sweep. The use of long, low-power inversion pulses (100 ms) reduced specific absorption rate requirements. The symmetric frequency sweep over both pulses provided good lipid suppression (>90%), in addition to a reduced loss in metabolite signal-to-noise ratio (SNR), compared with conventional IR suppression (52-70%). The metabolic mapping over the whole brain slice was not limited to a rectangular region of interest. 2D-GRAPPA provided acceleration up to a factor of nine for in vivo FID-MRSI without a substantial increase in g-factors (<1.1). A 64 × 64 matrix can be acquired with a common repetition time of ~1.3 s in only 8 min without lipid artefacts caused by acceleration. Overall, we present a fast and robust MRSI method, using combined double IR fat suppression and 2D-GRAPPA acceleration, which may be used in (pre)clinical studies of the brain at 7 T. © 2015 The Authors. NMR in Biomedicine published by John Wiley & Sons Ltd.

  9. Flip-Flop Digital Modulator

    NASA Technical Reports Server (NTRS)

    Eno, R. F.

    1984-01-01

    Clock switched on and off in response to data signal. Flip-flop modulator generates square-wave carrier frequency that is half clock frequency and turns carrier on and off. Final demodulator output logical inverse of data input.

  10. Application of time–frequency wavelet analysis in the reflectometry of thin films

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Astaf’ev, S. B., E-mail: bard@crys.ras.ru; Shchedrin, B. M.; Yanusova, L. G.

    2017-03-15

    The application of time–frequency wavelet analysis for solving the reflectometry inverse problem is considered. It is shown that a simultaneous transform of specular intensity curve, depending on the grazing angle and spatial frequency, allows one to determine not only the thickness but also the alteration order of individual regions (layers) with characteristic behavior of electron density. This information makes it possible to reconstruct the electron density profile in the film cross section as a whole (i.e., to solve the inverse reflectometry problem). The application of the time–frequency transform is illustrated by examples of reconstructing (based on X-ray reflectivity data) themore » layer alternation order in models of two-layer films with inverted arrangement of layers and a four-layer film on a solid substrate.« less

  11. Finite-element time-domain modeling of electromagnetic data in general dispersive medium using adaptive Padé series

    NASA Astrophysics Data System (ADS)

    Cai, Hongzhu; Hu, Xiangyun; Xiong, Bin; Zhdanov, Michael S.

    2017-12-01

    The induced polarization (IP) method has been widely used in geophysical exploration to identify the chargeable targets such as mineral deposits. The inversion of the IP data requires modeling the IP response of 3D dispersive conductive structures. We have developed an edge-based finite-element time-domain (FETD) modeling method to simulate the electromagnetic (EM) fields in 3D dispersive medium. We solve the vector Helmholtz equation for total electric field using the edge-based finite-element method with an unstructured tetrahedral mesh. We adopt the backward propagation Euler method, which is unconditionally stable, with semi-adaptive time stepping for the time domain discretization. We use the direct solver based on a sparse LU decomposition to solve the system of equations. We consider the Cole-Cole model in order to take into account the frequency-dependent conductivity dispersion. The Cole-Cole conductivity model in frequency domain is expanded using a truncated Padé series with adaptive selection of the center frequency of the series for early and late time. This approach can significantly increase the accuracy of FETD modeling.

  12. Predicting the effect of relaxation during frequency-selective adiabatic pulses

    NASA Astrophysics Data System (ADS)

    Pfaff, Annalise R.; McKee, Cailyn E.; Woelk, Klaus

    2017-11-01

    Adiabatic half and full passages are invaluable for achieving uniform, B1-insensitive excitation or inversion of macroscopic magnetization across a well-defined range of NMR frequencies. To accomplish narrow frequency ranges with adiabatic pulses (<100 Hz), long pulse durations at low RF power levels are necessary, and relaxation during these pulses may no longer be negligible. A numerical, discrete recursive combination of the Bloch equations for longitudinal and transverse relaxation with the optimized equation for adiabatic angular motion of magnetization is used to calculate the trajectory of magnetization including its relaxation during adiabatic hyperbolic secant pulses. The agreement of computer-calculated data with experimental results demonstrates that, in non-viscous, small-molecule fluids, it is possible to model magnetization and relaxation by considering standard T1 and T2 relaxation in the traditional rotating frame. The proposed model is aimed at performance optimizations of applications in which these pulses are employed. It differs from previous reports which focused on short high-power adiabatic pulses and relaxation that is governed by dipole-dipole interactions, cross polarization, or chemical exchange.

  13. An improved interface to process GPR data by means of microwave tomography

    NASA Astrophysics Data System (ADS)

    Catapano, Ilaria; Affinito, Antonio; Soldovieri, Francesco

    2015-04-01

    Ground Penetrating Radar (GPR) systems are well assessed non-invasive diagnostic tools, which are worth being considered in civil engineering surveys since they allow to gather information on constructive materials and techniques of manmade structures as well as on the aging and risk factors affecting their healthiness. However, the practical use of GPR depends strictly on the availability of data processing tools, on one hand, capable of providing reliable and easily interpretable images of the probed scenarios and, on the other side, easy to be used by not expert users. In this frame, 2D and full 3D microwave tomographic approaches based on the Born approximation have been developed and proved to be effective in several practical conditions [1, 2]. Generally speaking, a GPR data processing chain exploiting microwave tomography is made by two main steps: the pre-processing and the data inversion. The pre-processing groups standard procedures like start time correction, muting and background removal, which are performed in time domain to remove the direct antennas coupling, to reduce noise and to improve the targets footprint. The data inversion faces the imaging as the solution of a linear inverse scattering problem in the frequency domain. Hence, a linear integral equation relating the scattered field (i.e. the data) to the unknown electric contrast function is solved by using the truncated Singular Value Decomposition (SVD) as a regularized inversion scheme. Pre-processing and the data inversion are linked by a Discrete Fourier Transform (DFT), which allows to pass from the time domain to the frequency domain. In this respect, a frequency analysis of the GPR signals (traces) is also performed to identify the actual frequency range of the data. Unfortunately, the adoption of microwave tomography is strongly subjected to the involvement of expert people capable of managing properly the processing chain. To overcome this drawback, a couple of years ago, an end-user friendly software interface was developed to make possible a simple management of 2D microwave tomographic approaches [3]. Aim of this communication, is to present a novel interface, which is a significantly improved version with respect to the previous one. In particular, the new interface allows both 2D and full 3D imaging by taking as input GPR data gathered by means of different measurement configurations, i.e. by using down looking systems, with the antenna located close to the air-medium interface or at non negligible (in terms of the probing wavelength) distance from it, as well as by means of airborne and forward looking systems. In this frame, the users can select the data format among those of the most common commercial GPR systems or process data gathered by means of GPR prototypes, provided that they are saved in ASCII format. Moreover, the users can perform all the steps, which are needed to obtain tomographic images, and select the Born approximation based approach most suitable to the adopted measurement configuration. Raw-radargrams, intermediate and final results can be displayed for users convenience. REFERENCES [1] I. Catapano, R. Di Napoli, F. Soldovieri, M. Bavusi, A. Loperte, J. Dumoulin, "Structural monitoring via microwave tomography-enhanced GPR: the Montagnole test site", J. Geophys. Eng. 9, S100-S107, 2012. [2] I. Catapano, A. Affinito, G. Gennarelli, F.di Maio, A. Loperte, F. Soldovieri, "Full three-dimensional imaging via ground penetrating radar: assessment in controlled conditions and on field for archaeological prospecting", Appl. Phys. A, 2013, DOI 10.1007/s00339-013-8053-0. [3] I. Catapano, A. Affinito, F. Soldovieri, A user friendly interface for microwave tomography enhanced GPR surveys", EGU General Assembly 2013, vol. 15.

  14. Sensitivity to envelope-based interaural delays at high frequencies: center frequency affects the envelope rate-limitation.

    PubMed

    Bernstein, Leslie R; Trahiotis, Constantine

    2014-02-01

    Sensitivity to ongoing interaural temporal disparities (ITDs) was measured using bandpass-filtered pulse trains centered at 4600, 6500, or 9200 Hz. Save for minor differences in the exact center frequencies, those target stimuli were those employed by Majdak and Laback [J. Acoust. Soc. Am. 125, 3903-3913 (2009)]. At each center frequency, threshold ITD was measured for pulse repetition rates ranging from 64 to 609 Hz. The results and quantitative predictions by a cross-correlation-based model indicated that (1) at most pulse repetition rates, threshold ITD increased with center frequency, (2) the cutoff frequency of the putative envelope low-pass filter that determines sensitivity to ITD at high envelope rates appears to be inversely related to center frequency, and (3) both outcomes were accounted for by assuming that, independent of the center frequency, the listeners' decision variable was a constant criterion change in interaural correlation of the stimuli as processed internally. The finding of an inverse relation between center frequency and the envelope rate limitation, while consistent with much prior literature, runs counter to the conclusion reached by Majdak and Laback.

  15. A new principle technic for the transformation from frequency domain to time domain

    NASA Astrophysics Data System (ADS)

    Gao, Ben-Qing

    2017-03-01

    A principle technic for the transformation from frequency domain to time domain is presented. Firstly, a special type of frequency domain transcendental equation is obtained for an expected frequency domain parameter which is a rational or irrational fraction expression. Secondly, the inverse Laplace transformation is performed. When the two time-domain factors corresponding to the two frequency domain factors at two sides of frequency domain transcendental equation are known quantities, a time domain transcendental equation is reached. At last, the expected time domain parameter corresponding to the expected frequency domain parameter can be solved by the inverse convolution process. Proceeding from rational or irrational fraction expression, all solving process is provided. In the meantime, the property of time domain sequence is analyzed and the strategy for choosing the parameter values is described. Numerical examples are presented to verify the proposed theory and technic. Except for rational or irrational fraction expressions, examples of complex relative permittivity of water and plasma are used as verification method. The principle method proposed in the paper can easily solve problems which are difficult to be solved by Laplace transformation.

  16. Small impact craters in the lunar regolith - Their morphologies, relative ages, and rates of formation

    USGS Publications Warehouse

    Moore, H.J.; Boyce, J.M.; Hahn, D.A.

    1980-01-01

    Apparently, there are two types of size-frequency distributions of small lunar craters (???1-100 m across): (1) crater production distributions for which the cumulative frequency of craters is an inverse function of diameter to power near 2.8, and (2) steady-state distributions for which the cumulative frequency of craters is inversely proportional to the square of their diameters. According to theory, cumulative frequencies of craters in each morphologic category within the steady-state should also be an inverse function of the square of their diameters. Some data on frequency distribution of craters by morphologic types are approximately consistent with theory, whereas other data are inconsistent with theory. A flux of crater producing objects can be inferred from size-frequency distributions of small craters on the flanks and ejecta of craters of known age. Crater frequency distributions and data on the craters Tycho, North Ray, Cone, and South Ray, when compared with the flux of objects measured by the Apollo Passive Seismometer, suggest that the flux of objects has been relatively constant over the last 100 m.y. (within 1/3 to 3 times of the flux estimated for Tycho). Steady-state frequency distributions for craters in several morphologic categories formed the basis for estimating the relative ages of craters and surfaces in a system used during the Apollo landing site mapping program of the U.S. Geological Survey. The relative ages in this system are converted to model absolute ages that have a rather broad range of values. The range of values of the absolute ages are between about 1/3 to 3 times the assigned model absolute age. ?? 1980 D. Reidel Publishing Co.

  17. Effects of Inversions on Within- and Between-Species Recombination and Divergence

    PubMed Central

    Stevison, Laurie S.; Hoehn, Kenneth B.; Noor, Mohamed A. F.

    2011-01-01

    Chromosomal inversions disrupt recombination in heterozygotes by both reducing crossing-over within inverted regions and increasing it elsewhere in the genome. The reduction of recombination in inverted regions facilitates the maintenance of hybridizing species, as outlined by various models of chromosomal speciation. We present a comprehensive comparison of the effects of inversions on recombination rates and on nucleotide divergence. Within an inversion differentiating Drosophila pseudoobscura and Drosophila persimilis, we detected one double recombinant among 9,739 progeny from F1 hybrids screened, consistent with published double-crossover frequencies observed within species. Despite similar rates of exchange within and between species, we found no sequence-based evidence of ongoing gene exchange between species within this inversion, but significant exchange was inferred within species. We also observed greater differentiation at regions near inversion breakpoints between species versus within species. Moreover, we observed strong “interchromosomal effect” (higher recombination in inversion heterozygotes between species) with up to 9-fold higher recombination rates along collinear segments of chromosome two in hybrids. Further, we observed that regions most susceptible to changes in recombination rates corresponded to regions with lower recombination rates in homokaryotypes. Finally, we showed that interspecies nucleotide divergence is lower in regions with greater increases in recombination rate, potentially resulting from greater interspecies exchange. Overall, we have identified several similarities and differences between inversions segregating within versus between species in their effects on recombination and divergence. We conclude that these differences are most likely due to lower frequency of heterokaryotypes and to fitness consequences from the accumulation of various incompatibilities between species. Additionally, we have identified possible effects of inversions on interspecies gene exchange that had not been considered previously. PMID:21828374

  18. Non-Random Inversion Landscapes in Prokaryotic Genomes Are Shaped by Heterogeneous Selection Pressures.

    PubMed

    Repar, Jelena; Warnecke, Tobias

    2017-08-01

    Inversions are a major contributor to structural genome evolution in prokaryotes. Here, using a novel alignment-based method, we systematically compare 1,651 bacterial and 98 archaeal genomes to show that inversion landscapes are frequently biased toward (symmetric) inversions around the origin-terminus axis. However, symmetric inversion bias is not a universal feature of prokaryotic genome evolution but varies considerably across clades. At the extremes, inversion landscapes in Bacillus-Clostridium and Actinobacteria are dominated by symmetric inversions, while there is little or no systematic bias favoring symmetric rearrangements in archaea with a single origin of replication. Within clades, we find strong but clade-specific relationships between symmetric inversion bias and different features of adaptive genome architecture, including the distance of essential genes to the origin of replication and the preferential localization of genes on the leading strand. We suggest that heterogeneous selection pressures have converged to produce similar patterns of structural genome evolution across prokaryotes. © The Author 2017. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

  19. Trade wind inversion variability, dynamics and future change in Hawai'i

    NASA Astrophysics Data System (ADS)

    Cao, Guangxia

    Using 1979-2003 radiosonde data at Hilo and Lihu'e, Hawai'i, the trade-wind inversion (TWI) is found to occur approximately 82% of the time at each station, with average base heights of 2225 +/- 14.3 m (781.9 +/- 1.4 hPa) for Hilo and 2076 +/- 12.5 m (798.8 +/- 1.2 hPa) for Lihu'e. A Weather Research and Forecast (WRF) meso-scale meteorological simulation suggests that island topography and heating contribute to the lifting of the TWI base at Hilo. Inversion base height has a September maximum and a secondary maximum in April. Frequency of inversion occurrence is significantly higher during winters and lower during summers of El Nino years. During the period of 1979-2003, the inversion frequency of occurrence is on upward trend at Hilo for spring (MAM), summer (JJA), and fall (SON) seasons and at Lihu'e for all seasons and for annual values. Composite analysis shows that patterns of geopotential height (GPH), air temperature, u- and v-wind, omega wind, relative and specific humidity, upward longwave radiation flux, net longwave radiation flux, precipitable water, convective precipitation rate, and total cloud cover significantly respond to the TWI base height. For example, the GPH pattern contains a distinctive Pacific North America Teleconnection (PNA) signature, and the magnitudes of PNA centers over 45°N, 165°W for the difference between none and inversion is over 40 m at 200 hPa and 25 m at 850 hPa. The monthly composites show that months with lower (higher) inversion base height and higher (lower) inversion occurrence frequency are linked with the following characteristics: lower (higher) GPH anomalies centered at 30°N, 160°W, lower (higher) temperature anomalies within 300--700 hPa, stronger (weaker) easterly at low levels and northerly anomaly over Hawai'i, and small upward (downward) vertical wind or rising (sinking) motion north of Hawai'i. Using the above characteristics to study the Community Climate System Model (CCSM) composites leads to the prediction that the TWI under increased CO2 forcing atmosphere will be lower in base height and more frequently.

  20. Estimation of Uncertainties of Full Moment Tensors

    DTIC Science & Technology

    2017-10-06

    Nevada Test Site (tab. 1 of Ford et al., 2009). Figure 1 shows the three regions and the stations used within the moment tensor inversions . For the...and additional bandpass filtering, were applied during the moment tensor inversions . We use high-frequency P waves for the Uturuncu and NTS events...reliable when we align the P waves on the observed P arrival time. 3.2 Methods Seismic moment tensor inversion requires specifying a misfit function

  1. CSAMT Data Processing with Source Effect and Static Corrections, Application of Occam's Inversion, and Its Application in Geothermal System

    NASA Astrophysics Data System (ADS)

    Hamdi, H.; Qausar, A. M.; Srigutomo, W.

    2016-08-01

    Controlled source audio-frequency magnetotellurics (CSAMT) is a frequency-domain electromagnetic sounding technique which uses a fixed grounded dipole as an artificial signal source. Measurement of CSAMT with finite distance between transmitter and receiver caused a complex wave. The shifted of the electric field due to the static effect caused elevated resistivity curve up or down and affects the result of measurement. The objective of this study was to obtain data that have been corrected for source and static effects as to have the same characteristic as MT data which are assumed to exhibit plane wave properties. Corrected CSAMT data were inverted to reveal subsurface resistivity model. Source effect correction method was applied to eliminate the effect of the signal source and static effect was corrected by using spatial filtering technique. Inversion method that used in this study is the Occam's 2D Inversion. The results of inversion produces smooth models with a small misfit value, it means the model can describe subsurface conditions well. Based on the result of inversion was predicted measurement area is rock that has high permeability values with rich hot fluid.

  2. Frozen Gaussian approximation for 3D seismic tomography

    NASA Astrophysics Data System (ADS)

    Chai, Lihui; Tong, Ping; Yang, Xu

    2018-05-01

    Three-dimensional (3D) wave-equation-based seismic tomography is computationally challenging in large scales and high-frequency regime. In this paper, we apply the frozen Gaussian approximation (FGA) method to compute 3D sensitivity kernels and seismic tomography of high-frequency. Rather than standard ray theory used in seismic inversion (e.g. Kirchhoff migration and Gaussian beam migration), FGA is used to compute the 3D high-frequency sensitivity kernels for travel-time or full waveform inversions. Specifically, we reformulate the equations of the forward and adjoint wavefields for the purpose of convenience to apply FGA, and with this reformulation, one can efficiently compute the Green’s functions whose convolutions with source time function produce wavefields needed for the construction of 3D kernels. Moreover, a fast summation method is proposed based on local fast Fourier transform which greatly improves the speed of reconstruction as the last step of FGA algorithm. We apply FGA to both the travel-time adjoint tomography and full waveform inversion (FWI) on synthetic crosswell seismic data with dominant frequencies as high as those of real crosswell data, and confirm again that FWI requires a more sophisticated initial velocity model for the convergence than travel-time adjoint tomography. We also numerically test the accuracy of applying FGA to local earthquake tomography. This study paves the way to directly apply wave-equation-based seismic tomography methods into real data around their dominant frequencies.

  3. A parallel algorithm for 2D visco-acoustic frequency-domain full-waveform inversion: application to a dense OBS data set

    NASA Astrophysics Data System (ADS)

    Sourbier, F.; Operto, S.; Virieux, J.

    2006-12-01

    We present a distributed-memory parallel algorithm for 2D visco-acoustic full-waveform inversion of wide-angle seismic data. Our code is written in fortran90 and use MPI for parallelism. The algorithm was applied to real wide-angle data set recorded by 100 OBSs with a 1-km spacing in the eastern-Nankai trough (Japan) to image the deep structure of the subduction zone. Full-waveform inversion is applied sequentially to discrete frequencies by proceeding from the low to the high frequencies. The inverse problem is solved with a classic gradient method. Full-waveform modeling is performed with a frequency-domain finite-difference method. In the frequency-domain, solving the wave equation requires resolution of a large unsymmetric system of linear equations. We use the massively parallel direct solver MUMPS (http://www.enseeiht.fr/irit/apo/MUMPS) for distributed-memory computer to solve this system. The MUMPS solver is based on a multifrontal method for the parallel factorization. The MUMPS algorithm is subdivided in 3 main steps: a symbolic analysis step that performs re-ordering of the matrix coefficients to minimize the fill-in of the matrix during the subsequent factorization and an estimation of the assembly tree of the matrix. Second, the factorization is performed with dynamic scheduling to accomodate numerical pivoting and provides the LU factors distributed over all the processors. Third, the resolution is performed for multiple sources. To compute the gradient of the cost function, 2 simulations per shot are required (one to compute the forward wavefield and one to back-propagate residuals). The multi-source resolutions can be performed in parallel with MUMPS. In the end, each processor stores in core a sub-domain of all the solutions. These distributed solutions can be exploited to compute in parallel the gradient of the cost function. Since the gradient of the cost function is a weighted stack of the shot and residual solutions of MUMPS, each processor computes the corresponding sub-domain of the gradient. In the end, the gradient is centralized on the master processor using a collective communation. The gradient is scaled by the diagonal elements of the Hessian matrix. This scaling is computed only once per frequency before the first iteration of the inversion. Estimation of the diagonal terms of the Hessian requires performing one simulation per non redondant shot and receiver position. The same strategy that the one used for the gradient is used to compute the diagonal Hessian in parallel. This algorithm was applied to a dense wide-angle data set recorded by 100 OBSs in the eastern Nankai trough, offshore Japan. Thirteen frequencies ranging from 3 and 15 Hz were inverted. Tweny iterations per frequency were computed leading to 260 tomographic velocity models of increasing resolution. The velocity model dimensions are 105 km x 25 km corresponding to a finite-difference grid of 4201 x 1001 grid with a 25-m grid interval. The number of shot was 1005 and the number of inverted OBS gathers was 93. The inversion requires 20 days on 6 32-bits bi-processor nodes with 4 Gbytes of RAM memory per node when only the LU factorization is performed in parallel. Preliminary estimations of the time required to perform the inversion with the fully-parallelized code is 6 and 4 days using 20 and 50 processors respectively.

  4. Heterogeneous Multifrequency Direct Inversion (HMDI) for magnetic resonance elastography with application to a clinical brain exam.

    PubMed

    Barnhill, Eric; Davies, Penny J; Ariyurek, Cemre; Fehlner, Andreas; Braun, Jürgen; Sack, Ingolf

    2018-05-01

    A new viscoelastic wave inversion method for MRE, called Heterogeneous Multifrequency Direct Inversion (HMDI), was developed which accommodates heterogeneous elasticity within a direct inversion (DI) by incorporating first-order gradients and combining results from a narrow band of multiple frequencies. The method is compared with a Helmholtz-type DI, Multifrequency Dual Elasto-Visco inversion (MDEV), both on ground-truth Finite Element Method simulations at varied noise levels and a prospective in vivo brain cohort of 48 subjects ages 18-65. In simulated data, MDEV recovered background material within 5% and HMDI within 1% of prescribed up to SNR of 20 dB. In vivo HMDI and MDEV were then combined with segmentation from SPM to create a fully automated "brain palpation" exam for both whole brain (WB), and brain white matter (WM), measuring two parameters, the complex modulus magnitude |G*| , which measures tissue "stiffness", and the slope of |G*| values across frequencies, a measure of viscous dispersion. |G*| values for MDEV and HMDI were comparable to the literature (for a 3-frequency set centered at 50 Hz, WB means were 2.17 and 2.15 kPa respectively, and WM means were 2.47 and 2.49 kPa respectively). Both methods showed moderate correlation to age in both WB and WM, for both |G*| and |G*| slope, with Pearson's r ≥ 0.4 in the most sensitive frequency sets. In comparison to MDEV, HMDI showed better preservation of recovered target shapes, more noise-robustness, and stabler recovery values in regions with rapid property change, however summary statistics for both methods were quite similar. By eliminating homogeneity assumptions within a fast, fully automatic, regularization-free direct inversion, HMDI appears to be a worthwhile addition to the MRE image reconstruction repertoire. In addition to supporting the literature showing decrease in brain viscoelasticity with age, our work supports a wide range of inter-individual variation in brain MRE results. Copyright © 2018 Elsevier B.V. All rights reserved.

  5. Sexual selection and genetic colour polymorphisms in animals.

    PubMed

    Wellenreuther, Maren; Svensson, Erik I; Hansson, Bengt

    2014-11-01

    Genetic colour polymorphisms are widespread across animals and often subjected to complex selection regimes. Traditionally, colour morphs were used as simple visual markers to measure allele frequency changes in nature, selection, population divergence and speciation. With advances in sequencing technology and analysis methods, several model systems are emerging where the molecular targets of selection are being described. Here, we discuss recent studies on the genetics of sexually selected colour polymorphisms, aiming at (i) reviewing the evidence of sexual selection on colour polymorphisms, (ii) highlighting the genetic architecture, molecular and developmental basis underlying phenotypic colour diversification and (iii) discuss how the maintenance of such polymorphisms might be facilitated or constrained by these. Studies of the genetic architecture of colour polymorphism point towards the importance of tight clustering of colour loci with other trait loci, such as in the case of inversions and supergene structures. Other interesting findings include linkage between colour loci and mate preferences or sex determination, and the role of introgression and regulatory variation in fuelling polymorphisms. We highlight that more studies are needed that explicitly integrate fitness consequences of sexual selection on colour with the underlying molecular targets of colour to gain insights into the evolutionary consequences of sexual selection on polymorphism maintenance. © 2014 John Wiley & Sons Ltd.

  6. Eco-Evolutionary Genomics of Chromosomal Inversions.

    PubMed

    Wellenreuther, Maren; Bernatchez, Louis

    2018-05-03

    Chromosomal inversions have long fascinated evolutionary biologists due to their suppression of recombination, which can protect co-adapted alleles. Emerging research documents that inversions are commonly linked to spectacular phenotypes and have a pervasive role in eco-evolutionary processes, from mating systems, social organisation, environmental adaptation, and reproductive isolation to speciation. Studies also reveal that inversions are taxonomically widespread, with many being old and large, and that balancing selection is commonly facilitating their maintenance. This challenges the traditional view that the role of balancing selection in maintaining variation is relatively minor. The ubiquitous importance of inversions in ecological and evolutionary processes suggests that structural variation should be better acknowledged and integrated in studies pertaining to the molecular basis of adaptation and speciation. Copyright © 2018 Elsevier Ltd. All rights reserved.

  7. Long-period GPS waveforms. What can GPS bring to Earth seismic velocity models?

    NASA Astrophysics Data System (ADS)

    Kelevitz, Krisztina; Houlié, Nicolas; Boschi, Lapo; Nissen-Meyer, Tarje; Giardini, Domenico

    2014-05-01

    It is now commonly admitted that high rate GPS observations can provide reliable surface displacement waveforms (Cervelli, et al., 2001; Langbein, et al., 2006; Houlié, et al., 2006; Houlié et al., 2011). For long-period (T>5s) transients, it was shown that GPS and seismometer (STS-1) displacements are in agreement at least for vertical component (Houlié, et al., Sci. Rep. 2011). We propose here to supplement existing long-period seismic networks with high rate (>= 1Hz) GPS data in order to improve the resolution of global seismic velocity models. GPS measurements are providing a wide range of frequencies, going beyond the range of STS-1 in the low frequency end. Nowadays, almost 10.000 GPS receivers would be able to record data at 1 Hz with 3000+ stations already streaming data in Real-Time (RT). The reasons for this quick expansion are the price of receivers, their low maintenance, and the wide range of activities they can be used for (transport, science, public apps, navigation, etc.). We are presenting work completed on the 1Hz GPS records of the Hokkaido earthquake (25th of September, 2003, Mw=8.3). 3D Waveforms have been computed with an improved, stabilised inversion algorithm in order to constrain the ground motion history. Through the better resolution of inversion of the GPS phase observations, we determine displacement waveforms of frequencies ranging from 0.77 mHz to 330 mHz for a selection of sites. We compare inverted GPS waveforms with STS-1 waveforms and synthetic waveforms computed using 3D global wave propagation with SPECFEM. At co-located sites (STS-1 and GPS located within 10km) the agreement is good for the vertical component between seismic (both real and synthetic) and GPS waveforms.

  8. Part-to-itself model inversion in process compensated resonance testing

    NASA Astrophysics Data System (ADS)

    Mayes, Alexander; Jauriqui, Leanne; Biedermann, Eric; Heffernan, Julieanne; Livings, Richard; Aldrin, John C.; Goodlet, Brent; Mazdiyasni, Siamack

    2018-04-01

    Process Compensated Resonance Testing (PCRT) is a non-destructive evaluation (NDE) method involving the collection and analysis of a part's resonance spectrum to characterize its material or damage state. Prior work used the finite element method (FEM) to develop forward modeling and model inversion techniques. In many cases, the inversion problem can become confounded by multiple parameters having similar effects on a part's resonance frequencies. To reduce the influence of confounding parameters and isolate the change in a part (e.g., creep), a part-to-itself (PTI) approach can be taken. A PTI approach involves inverting only the change in resonance frequencies from the before and after states of a part. This approach reduces the possible inversion parameters to only those that change in response to in-service loads and damage mechanisms. To evaluate the effectiveness of using a PTI inversion approach, creep strain and material properties were estimated in virtual and real samples using FEM inversion. Virtual and real dog bone samples composed of nickel-based superalloy Mar-M-247 were examined. Virtual samples were modeled with typically observed variations in material properties and dimensions. Creep modeling was verified with the collected resonance spectra from an incrementally crept physical sample. All samples were inverted against a model space that allowed for change in the creep damage state and the material properties but was blind to initial part dimensions. Results quantified the capabilities of PTI inversion in evaluating creep strain and material properties, as well as its sensitivity to confounding initial dimensions.

  9. Model based Inverse Methods for Sizing Cracks of Varying Shape and Location in Bolt hole Eddy Current (BHEC) Inspections (Postprint)

    DTIC Science & Technology

    2016-02-10

    using bolt hole eddy current (BHEC) techniques. Data was acquired for a wide range of crack sizes and shapes, including mid- bore , corner and through...to select the most appropriate VIC-3D surrogate model for subsequent crack sizing inversion step. Inversion results for select mid- bore , through and...the flaw. 15. SUBJECT TERMS Bolt hole eddy current (BHEC); mid- bore , corner and through-thickness crack types; VIC-3D generated surrogate models

  10. The structured ancestral selection graph and the many-demes limit.

    PubMed

    Slade, Paul F; Wakeley, John

    2005-02-01

    We show that the unstructured ancestral selection graph applies to part of the history of a sample from a population structured by restricted migration among subpopulations, or demes. The result holds in the limit as the number of demes tends to infinity with proportionately weak selection, and we have also made the assumptions of island-type migration and that demes are equivalent in size. After an instantaneous sample-size adjustment, this structured ancestral selection graph converges to an unstructured ancestral selection graph with a mutation parameter that depends inversely on the migration rate. In contrast, the selection parameter for the population is independent of the migration rate and is identical to the selection parameter in an unstructured population. We show analytically that estimators of the migration rate, based on pairwise sequence differences, derived under the assumption of neutrality should perform equally well in the presence of weak selection. We also modify an algorithm for simulating genealogies conditional on the frequencies of two selected alleles in a sample. This permits efficient simulation of stronger selection than was previously possible. Using this new algorithm, we simulate gene genealogies under the many-demes ancestral selection graph and identify some situations in which migration has a strong effect on the time to the most recent common ancestor of the sample. We find that a similar effect also increases the sensitivity of the genealogy to selection.

  11. Polarization transfer NMR imaging

    DOEpatents

    Sillerud, Laurel O.; van Hulsteyn, David B.

    1990-01-01

    A nuclear magnetic resonance (NMR) image is obtained with spatial information modulated by chemical information. The modulation is obtained through polarization transfer from a first element representing the desired chemical, or functional, information, which is covalently bonded and spin-spin coupled with a second element effective to provide the imaging data. First and second rf pulses are provided at first and second frequencies for exciting the imaging and functional elements, with imaging gradients applied therebetween to spatially separate the nuclei response for imaging. The second rf pulse is applied at a time after the first pulse which is the inverse of the spin coupling constant to select the transfer element nuclei which are spin coupled to the functional element nuclei for imaging. In a particular application, compounds such as glucose, lactate, or lactose, can be labeled with .sup.13 C and metabolic processes involving the compounds can be imaged with the sensitivity of .sup.1 H and the selectivity of .sup.13 C.

  12. Evolution of Synonymous Codon Usage in Neurospora tetrasperma and Neurospora discreta

    PubMed Central

    Whittle, C. A.; Sun, Y.; Johannesson, H.

    2011-01-01

    Neurospora comprises a primary model system for the study of fungal genetics and biology. In spite of this, little is known about genome evolution in Neurospora. For example, the evolution of synonymous codon usage is largely unknown in this genus. In the present investigation, we conducted a comprehensive analysis of synonymous codon usage and its relationship to gene expression and gene length (GL) in Neurospora tetrasperma and Neurospora discreta. For our analysis, we examined codon usage among 2,079 genes per organism and assessed gene expression using large-scale expressed sequenced tag (EST) data sets (279,323 and 453,559 ESTs for N. tetrasperma and N. discreta, respectively). Data on relative synonymous codon usage revealed 24 codons (and two putative codons) that are more frequently used in genes with high than with low expression and thus were defined as optimal codons. Although codon-usage bias was highly correlated with gene expression, it was independent of selectively neutral base composition (introns); thus demonstrating that translational selection drives synonymous codon usage in these genomes. We also report that GL (coding sequences [CDS]) was inversely associated with optimal codon usage at each gene expression level, with highly expressed short genes having the greatest frequency of optimal codons. Optimal codon frequency was moderately higher in N. tetrasperma than in N. discreta, which might be due to variation in selective pressures and/or mating systems. PMID:21402862

  13. Improving the accurate assessment of a layered shear-wave velocity model using joint inversion of the effective Rayleigh wave and Love wave dispersion curves

    NASA Astrophysics Data System (ADS)

    Yin, X.; Xia, J.; Xu, H.

    2016-12-01

    Rayleigh and Love waves are two types of surface waves that travel along a free surface.Based on the assumption of horizontal layered homogenous media, Rayleigh-wave phase velocity can be defined as a function of frequency and four groups of earth parameters: P-wave velocity, SV-wave velocity, density and thickness of each layer. Unlike Rayleigh waves, Love-wave phase velocities of a layered homogenous earth model could be calculated using frequency and three groups of earth properties: SH-wave velocity, density, and thickness of each layer. Because the dispersion of Love waves is independent of P-wave velocities, Love-wave dispersion curves are much simpler than Rayleigh wave. The research of joint inversion methods of Rayleigh and Love dispersion curves is necessary. (1) This dissertation adopts the combinations of theoretical analysis and practical applications. In both lateral homogenous media and radial anisotropic media, joint inversion approaches of Rayleigh and Love waves are proposed to improve the accuracy of S-wave velocities.A 10% random white noise and a 20% random white noise are added to the synthetic dispersion curves to check out anti-noise ability of the proposed joint inversion method.Considering the influences of the anomalous layer, Rayleigh and Love waves are insensitive to those layers beneath the high-velocity layer or low-velocity layer and the high-velocity layer itself. Low sensitivities will give rise to high degree of uncertainties of the inverted S-wave velocities of these layers. Considering that sensitivity peaks of Rayleigh and Love waves separate at different frequency ranges, the theoretical analyses have demonstrated that joint inversion of these two types of waves would probably ameliorate the inverted model.The lack of surface-wave (Rayleigh or Love waves) dispersion data may lead to inaccuracy S-wave velocities through the single inversion of Rayleigh or Love waves, so this dissertation presents the joint inversion method of Rayleigh and Love waves which will improve the accuracy of S-wave velocities. Finally, a real-world example is applied to verify the accuracy and stability of the proposed joint inversion method. Keywords: Rayleigh wave; Love wave; Sensitivity analysis; Joint inversion method.

  14. Variable-permittivity linear inverse problem for the H(sub z)-polarized case

    NASA Technical Reports Server (NTRS)

    Moghaddam, M.; Chew, W. C.

    1993-01-01

    The H(sub z)-polarized inverse problem has rarely been studied before due to the complicated way in which the unknown permittivity appears in the wave equation. This problem is equivalent to the acoustic inverse problem with variable density. We have recently reported the solution to the nonlinear variable-permittivity H(sub z)-polarized inverse problem using the Born iterative method. Here, the linear inverse problem is solved for permittivity (epsilon) and permeability (mu) using a different approach which is an extension of the basic ideas of diffraction tomography (DT). The key to solving this problem is to utilize frequency diversity to obtain the required independent measurements. The receivers are assumed to be in the far field of the object, and plane wave incidence is also assumed. It is assumed that the scatterer is weak, so that the Born approximation can be used to arrive at a relationship between the measured pressure field and two terms related to the spatial Fourier transform of the two unknowns, epsilon and mu. The term involving permeability corresponds to monopole scattering and that for permittivity to dipole scattering. Measurements at several frequencies are used and a least squares problem is solved to reconstruct epsilon and mu. It is observed that the low spatial frequencies in the spectra of epsilon and mu produce inaccuracies in the results. Hence, a regularization method is devised to remove this problem. Several results are shown. Low contrast objects for which the above analysis holds are used to show that good reconstructions are obtained for both permittivity and permeability after regularization is applied.

  15. Viscoelastic material inversion using Sierra-SD and ROL

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Walsh, Timothy; Aquino, Wilkins; Ridzal, Denis

    2014-11-01

    In this report we derive frequency-domain methods for inverse characterization of the constitutive parameters of viscoelastic materials. The inverse problem is cast in a PDE-constrained optimization framework with efficient computation of gradients and Hessian vector products through matrix free operations. The abstract optimization operators for first and second derivatives are derived from first principles. Various methods from the Rapid Optimization Library (ROL) are tested on the viscoelastic inversion problem. The methods described herein are applied to compute the viscoelastic bulk and shear moduli of a foam block model, which was recently used in experimental testing for viscoelastic property characterization.

  16. Indoor detection of passive targets recast as an inverse scattering problem

    NASA Astrophysics Data System (ADS)

    Gottardi, G.; Moriyama, T.

    2017-10-01

    The wireless local area networks represent an alternative to custom sensors and dedicated surveillance systems for target indoor detection. The availability of the channel state information has opened the exploitation of the spatial and frequency diversity given by the orthogonal frequency division multiplexing. Such a fine-grained information can be used to solve the detection problem as an inverse scattering problem. The goal of the detection is to reconstruct the properties of the investigation domain, namely to estimate if the domain is empty or occupied by targets, starting from the measurement of the electromagnetic perturbation of the wireless channel. An innovative inversion strategy exploiting both the frequency and the spatial diversity of the channel state information is proposed. The target-dependent features are identified combining the Kruskal-Wallis test and the principal component analysis. The experimental validation points out the detection performance of the proposed method when applied to an existing wireless link of a WiFi architecture deployed in a real indoor scenario. False detection rates lower than 2 [%] have been obtained.

  17. Applications of Generalized Derivatives to Viscoelasticity.

    DTIC Science & Technology

    1979-11-01

    Integration Used to Evaluate the Inverse Transform 78 B-i Schematic of the Half-Space of Newtonian Fluid Bounded by a "Wetted" Surface 96 C-I The...of the response at discrete frequencies. The inverse transform of the response is evaluated numerically to produce the time history. The major drawback...of this method is the arduous task of calculating the inverse transform for every point in time at which the value of the response is required. The

  18. Laplace-domain waveform modeling and inversion for the 3D acoustic-elastic coupled media

    NASA Astrophysics Data System (ADS)

    Shin, Jungkyun; Shin, Changsoo; Calandra, Henri

    2016-06-01

    Laplace-domain waveform inversion reconstructs long-wavelength subsurface models by using the zero-frequency component of damped seismic signals. Despite the computational advantages of Laplace-domain waveform inversion over conventional frequency-domain waveform inversion, an acoustic assumption and an iterative matrix solver have been used to invert 3D marine datasets to mitigate the intensive computing cost. In this study, we develop a Laplace-domain waveform modeling and inversion algorithm for 3D acoustic-elastic coupled media by using a parallel sparse direct solver library (MUltifrontal Massively Parallel Solver, MUMPS). We precisely simulate a real marine environment by coupling the 3D acoustic and elastic wave equations with the proper boundary condition at the fluid-solid interface. In addition, we can extract the elastic properties of the Earth below the sea bottom from the recorded acoustic pressure datasets. As a matrix solver, the parallel sparse direct solver is used to factorize the non-symmetric impedance matrix in a distributed memory architecture and rapidly solve the wave field for a number of shots by using the lower and upper matrix factors. Using both synthetic datasets and real datasets obtained by a 3D wide azimuth survey, the long-wavelength component of the P-wave and S-wave velocity models is reconstructed and the proposed modeling and inversion algorithm are verified. A cluster of 80 CPU cores is used for this study.

  19. Anisotropic three-dimensional inversion of CSEM data using finite-element techniques on unstructured grids

    NASA Astrophysics Data System (ADS)

    Wang, Feiyan; Morten, Jan Petter; Spitzer, Klaus

    2018-05-01

    In this paper, we present a recently developed anisotropic 3-D inversion framework for interpreting controlled-source electromagnetic (CSEM) data in the frequency domain. The framework integrates a high-order finite-element forward operator and a Gauss-Newton inversion algorithm. Conductivity constraints are applied using a parameter transformation. We discretize the continuous forward and inverse problems on unstructured grids for a flexible treatment of arbitrarily complex geometries. Moreover, an unstructured mesh is more desirable in comparison to a single rectilinear mesh for multisource problems because local grid refinement will not significantly influence the mesh density outside the region of interest. The non-uniform spatial discretization facilitates parametrization of the inversion domain at a suitable scale. For a rapid simulation of multisource EM data, we opt to use a parallel direct solver. We further accelerate the inversion process by decomposing the entire data set into subsets with respect to frequencies (and transmitters if memory requirement is affordable). The computational tasks associated with each data subset are distributed to different processes and run in parallel. We validate the scheme using a synthetic marine CSEM model with rough bathymetry, and finally, apply it to an industrial-size 3-D data set from the Troll field oil province in the North Sea acquired in 2008 to examine its robustness and practical applicability.

  20. Molecular population genetics of X-linked genes in Drosophila pseudoobscura.

    PubMed Central

    Kovacevic, M; Schaeffer, S W

    2000-01-01

    This article presents a nucleotide sequence analysis of 500 bp determined in each of five X-linked genes, runt, sisterlessA, period, esterase 5, and Heat-shock protein 83, in 40 Drosophila pseudoobscura strains collected from two populations. Estimates of the neutral migration parameter for the five loci show that gene flow among D. pseudoobscura populations is sufficient to homogenize inversion frequencies across the range of the species. Nucleotide diversity at each locus fails to reject a neutral model of molecular evolution. The sample of 40 chromosomes included six Sex-ratio inversions, a series of three nonoverlapping inversions that are associated with a strong meiotic drive phenotype. The selection driven by the Sex-ratio meiotic drive element has not fixed variation across the X chromosome of D. pseudoobscura because, while significant linkage disequilibrium was observed within the sisterlessA, period, and esterase 5 genes, we did not find evidence for nonrandom association among loci. The Sex-ratio chromosome was estimated to be 25,000 years old based on the decomposition of linkage disequilibrium between esterase 5 and Heat-shock protein 83 or 1 million years old based on the net divergence of esterase 5 between Standard and Sex-ratio chromosomes. Genetic diversity was depressed within esterase 5 within Sex-ratio chromosomes, while the four other genes failed to show a reduction in heterozygosity in the Sex-ratio background. The reduced heterogeneity in esterase 5 is due either to its location near one of the Sex-ratio inversion breakpoints or that it is closely linked to a gene or genes responsible for the Sex-ratio meiotic drive system. PMID:10978282

  1. The occurrence of double strand DNA breaks is not the sole condition for meiotic crossing over in Drosophila melanogaster.

    PubMed

    Portin, P; Rantanen, M

    2000-01-01

    Analysis of the interchromosomal effects of In(2L + 2R)Cy, In(3L + 3R)LVM and their joint effect on the frequencies of single and double crossovers in the cv-v-f region of the X chromosome as well as interference showed that both inversions, occurring separately, increased the frequency of single as well as double crossovers and the coefficient of coincidence. However, when the inversions occurred together the frequencies of single crossovers no longer increased, but the frequency of double crossovers, as well as the coefficient of coincidence did increase. These results indicate firstly that the interchromosomal effects influence some precondition of exchange, but that this precondition is not an occurrence of double strand DNA breaks. Thus, the occurrence of double strand DNA breaks is not the sole condition for crossing over in Drosophila melanogaster.

  2. A simple device for long-term radar cross section recordings.

    PubMed

    Eskelinen, Pekka; Ruoskanen, Jukka; Peltonen, Jouni

    2009-05-01

    A sample and hold circuit with settable delay can be used for recording of radar echo amplitude variations having time scales up to 100 s at the selected range bin in systems utilizing short rf pulses. The design is based on two integrated circuits and gives 1% uncertainty for 70 ns pulses. The key benefit is a real-time display of lengthy amplitude variations because the sample rate is defined by the radar pulse repetition frequency. Additionally we get a reduction in file size at least by the inverse of the radar's duty cycle. Examples of 10 and 100 s recordings with a Ka-band short pulse radar are described.

  3. Recurrent DNA inversion rearrangements in the human genome

    PubMed Central

    Flores, Margarita; Morales, Lucía; Gonzaga-Jauregui, Claudia; Domínguez-Vidaña, Rocío; Zepeda, Cinthya; Yañez, Omar; Gutiérrez, María; Lemus, Tzitziki; Valle, David; Avila, Ma. Carmen; Blanco, Daniel; Medina-Ruiz, Sofía; Meza, Karla; Ayala, Erandi; García, Delfino; Bustos, Patricia; González, Víctor; Girard, Lourdes; Tusie-Luna, Teresa; Dávila, Guillermo; Palacios, Rafael

    2007-01-01

    Several lines of evidence suggest that reiterated sequences in the human genome are targets for nonallelic homologous recombination (NAHR), which facilitates genomic rearrangements. We have used a PCR-based approach to identify breakpoint regions of rearranged structures in the human genome. In particular, we have identified intrachromosomal identical repeats that are located in reverse orientation, which may lead to chromosomal inversions. A bioinformatic workflow pathway to select appropriate regions for analysis was developed. Three such regions overlapping with known human genes, located on chromosomes 3, 15, and 19, were analyzed. The relative proportion of wild-type to rearranged structures was determined in DNA samples from blood obtained from different, unrelated individuals. The results obtained indicate that recurrent genomic rearrangements occur at relatively high frequency in somatic cells. Interestingly, the rearrangements studied were significantly more abundant in adults than in newborn individuals, suggesting that such DNA rearrangements might start to appear during embryogenesis or fetal life and continue to accumulate after birth. The relevance of our results in regard to human genomic variation is discussed. PMID:17389356

  4. Chemically Patterned Inverse Opal Created by a Selective Photolysis Modification Process.

    PubMed

    Tian, Tian; Gao, Ning; Gu, Chen; Li, Jian; Wang, Hui; Lan, Yue; Yin, Xianpeng; Li, Guangtao

    2015-09-02

    Anisotropic photonic crystal materials have long been pursued for their broad applications. A novel method for creating chemically patterned inverse opals is proposed here. The patterning technique is based on selective photolysis of a photolabile polymer together with postmodification on released amine groups. The patterning method allows regioselective modification within an inverse opal structure, taking advantage of selective chemical reaction. Moreover, combined with the unique signal self-reporting feature of the photonic crystal, the fabricated structure is capable of various applications, including gradient photonic bandgap and dynamic chemical patterns. The proposed method provides the ability to extend the structural and chemical complexity of the photonic crystal, as well as its potential applications.

  5. [Frequency of intron 1 inversion of factor VIII gene in Chinese hemophilia A patients with case report of a female patient with heterozygous intron 1 inversion].

    PubMed

    Yan, Zhen-yu; Liang, Yan; Yan, Mei; Fan, Lian-kai; Xiao, Bai; Hua, Bao-lai; Liu, Jing-zhong; Zhao, Yong-qiang

    2008-10-21

    To investigate the frequency of intron 1 inversion (inv1) in FVIII gene in Chinese hemophilia A (HA) patients and to investigate the mechanism of pathogenesis. Peripheral blood samples were collected from 158 unrelated HA patients, aged 20 (1 - 73), including one female HA patient, aged 5, and several family members of a patient positive in inv1. One-stage method was used to assay the FVIII activity (FVIII:C). Long distance PCR and multiple PCR in duplex reactions were used to screen for the intron 22 inversion (inv22) and inv1 of the FVIII coding gene (F8). The F8 coding sequence was amplified with PCR and sequenced with an automatic sequencer. Two unrelated patients (pedigrees) were detected as inv1 positive with a positive rate of 1.26%. A rare female HA patient with inv1 was also discovered in a positive family (3 HA cases were found in this family and regarded as one case in calculating the total detection rate). The full length of FVIII was sequenced, and no other mutation was detected. There frequency of FVIII inv1 is low in Chinese HA patients compared with other populations. Female HA patients are heterozygous for FVIII inv1 and that may be resulted from nonrandom inactivation of X chromosome.

  6. 3-D decoupled inversion of complex conductivity data in the real number domain

    NASA Astrophysics Data System (ADS)

    Johnson, Timothy C.; Thomle, Jonathan

    2018-01-01

    Complex conductivity imaging (also called induced polarization imaging or spectral induced polarization imaging when conducted at multiple frequencies) involves estimating the frequency-dependent complex electrical conductivity distribution of the subsurface. The superior diagnostic capabilities provided by complex conductivity spectra have driven advancements in mechanistic understanding of complex conductivity as well as modelling and inversion approaches over the past several decades. In this work, we demonstrate the theory and application for an approach to 3-D modelling and inversion of complex conductivity data in the real number domain. Beginning from first principles, we demonstrate how the equations for the real and imaginary components of the complex potential may be decoupled. This leads to a description of the real and imaginary source current terms, and a corresponding assessment of error arising from an assumption necessary to complete the decoupled modelling. We show that for most earth materials, which exhibit relatively small phases (e.g. less than 0.2 radians) in complex conductivity, these errors become insignificant. For higher phase materials, the errors may be quantified and corrected through an iterative procedure. We demonstrate the accuracy of numerical forward solutions by direct comparison to corresponding analytic solutions. We demonstrate the inversion using both synthetic and field examples with data collected over a waste infiltration trench, at frequencies ranging from 0.5 to 7.5 Hz.

  7. Implementing wavelet inverse-transform processor with surface acoustic wave device.

    PubMed

    Lu, Wenke; Zhu, Changchun; Liu, Qinghong; Zhang, Jingduan

    2013-02-01

    The objective of this research was to investigate the implementation schemes of the wavelet inverse-transform processor using surface acoustic wave (SAW) device, the length function of defining the electrodes, and the possibility of solving the load resistance and the internal resistance for the wavelet inverse-transform processor using SAW device. In this paper, we investigate the implementation schemes of the wavelet inverse-transform processor using SAW device. In the implementation scheme that the input interdigital transducer (IDT) and output IDT stand in a line, because the electrode-overlap envelope of the input IDT is identical with the one of the output IDT (i.e. the two transducers are identical), the product of the input IDT's frequency response and the output IDT's frequency response can be implemented, so that the wavelet inverse-transform processor can be fabricated. X-112(0)Y LiTaO(3) is used as a substrate material to fabricate the wavelet inverse-transform processor. The size of the wavelet inverse-transform processor using this implementation scheme is small, so its cost is low. First, according to the envelope function of the wavelet function, the length function of the electrodes is defined, then, the lengths of the electrodes can be calculated from the length function of the electrodes, finally, the input IDT and output IDT can be designed according to the lengths and widths for the electrodes. In this paper, we also present the load resistance and the internal resistance as the two problems of the wavelet inverse-transform processor using SAW devices. The solutions to these problems are achieved in this study. When the amplifiers are subjected to the input end and output end for the wavelet inverse-transform processor, they can eliminate the influence of the load resistance and the internal resistance on the output voltage of the wavelet inverse-transform processor using SAW device. Copyright © 2012 Elsevier B.V. All rights reserved.

  8. High-frequency envelope inversion analysis of the 2003 Tokachi-Oki, JAPAN, earthquake (Mw8.0)

    NASA Astrophysics Data System (ADS)

    Nakahara, H.

    2004-12-01

    The 2003 Tokachi-Oki earthquake (Mw 8.0) took place on September 26, 2003 at the plate interface between the subducting Pacific plate and the Hokkaido island, northern Japan. The focal depth is around 30km and the focal mechanism is thrust type. This earthquake caused 2 missings, more than 100 injures, 2000 collapsed houses, and so on. Slip distribution on the fault plane was already estimated by inversion analyses of low-frequency seismograms. However, source characteristics for the earthquake in frequencies higher than 1 Hz is not so far clarified. In this study, we execute an envelope inversion analysis based on the method by Nakahara et al. (1998) and clarify the spatial distribution of high-frequency seismic energy radiation on the fault plane of this earthquake. We use three-component sum of mean squared velocity seismograms multiplied by a density of earth medium, which is called envelopes here, for the envelope inversion analysis. Three frequency bands of 1-2, 2-4, and 4-8 Hz are adopted. We use envelopes in the time window from the onset of S waves to the lapse time of 128 sec. Green functions of envelopes representing the energy propagation process through a scattering medium are calculated based on the radiative transfer theory, which are characterized by parameters of scattering attenuation and intrinsic absorption. We use the values obtained for eastern Hokkaido (Hoshiba, 1993). We assume the fault plane as follows: strike=249o, dip=15o, rake=130o, length=150km, width=165km with reference to a waveform inversion analysis in low frequencies (e.g. Yagi, 2003). We divide this fault plane into 110 subfaults, each of which is a 15km x 15km square. Rupture velocity is assumed to be constant. Seismic energy is radiated from a point source as soon as the rupture front passes the center of each subfault. Time function of energy radiation is assumed as a box-car function. The amount of seismic energy from all the subfaults and site amplification factors for all the stations are estimated by the envelope inversion method. Rupture velocity and the duration time of a box-car function should be estimated by a grid search. Theoretical envelopes calculated with best-fit parameters generally fit to observed ones. The rupture velocity and duration time were estimated as 3.0 km/s and 6 sec, respectively. The high-frequency seismic energy was found to be radiated mainly from two spots on the fault plane: The first one is the deeper part beneath the initial rupture point and the second is the southern shallow part of the fault plane. Radiated energy was estimated to be 7.2 × 1016J in the 1-8Hz band. Acknowledgements: We used strong-motion seismograms recorded by the K-NET and KiK-net of NIED, JAPAN.

  9. Accumulated energy norm for full waveform inversion of marine data

    NASA Astrophysics Data System (ADS)

    Shin, Changsoo; Ha, Wansoo

    2017-12-01

    Macro-velocity models are important for imaging the subsurface structure. However, the conventional objective functions of full waveform inversion in the time and the frequency domain have a limited ability to recover the macro-velocity model because of the absence of low-frequency information. In this study, we propose new objective functions that can recover the macro-velocity model by minimizing the difference between the zero-frequency components of the square of seismic traces. Instead of the seismic trace itself, we use the square of the trace, which contains low-frequency information. We apply several time windows to the trace and obtain zero-frequency information of the squared trace for each time window. The shape of the new objective functions shows that they are suitable for local optimization methods. Since we use the acoustic wave equation in this study, this method can be used for deep-sea marine data, in which elastic effects can be ignored. We show that the zero-frequency components of the square of the seismic traces can be used to recover macro-velocities from synthetic and field data.

  10. Gravitational dynamos and the low-frequency geomagnetic secular variation.

    PubMed

    Olson, P

    2007-12-18

    Self-sustaining numerical dynamos are used to infer the sources of low-frequency secular variation of the geomagnetic field. Gravitational dynamo models powered by compositional convection in an electrically conducting, rotating fluid shell exhibit several regimes of magnetic field behavior with an increasing Rayleigh number of the convection, including nearly steady dipoles, chaotic nonreversing dipoles, and chaotic reversing dipoles. The time average dipole strength and dipolarity of the magnetic field decrease, whereas the dipole variability, average dipole tilt angle, and frequency of polarity reversals increase with Rayleigh number. Chaotic gravitational dynamos have large-amplitude dipole secular variation with maximum power at frequencies corresponding to a few cycles per million years on Earth. Their external magnetic field structure, dipole statistics, low-frequency power spectra, and polarity reversal frequency are comparable to the geomagnetic field. The magnetic variability is driven by the Lorentz force and is characterized by an inverse correlation between dynamo magnetic and kinetic energy fluctuations. A constant energy dissipation theory accounts for this inverse energy correlation, which is shown to produce conditions favorable for dipole drift, polarity reversals, and excursions.

  11. Gravitational dynamos and the low-frequency geomagnetic secular variation

    PubMed Central

    Olson, P.

    2007-01-01

    Self-sustaining numerical dynamos are used to infer the sources of low-frequency secular variation of the geomagnetic field. Gravitational dynamo models powered by compositional convection in an electrically conducting, rotating fluid shell exhibit several regimes of magnetic field behavior with an increasing Rayleigh number of the convection, including nearly steady dipoles, chaotic nonreversing dipoles, and chaotic reversing dipoles. The time average dipole strength and dipolarity of the magnetic field decrease, whereas the dipole variability, average dipole tilt angle, and frequency of polarity reversals increase with Rayleigh number. Chaotic gravitational dynamos have large-amplitude dipole secular variation with maximum power at frequencies corresponding to a few cycles per million years on Earth. Their external magnetic field structure, dipole statistics, low-frequency power spectra, and polarity reversal frequency are comparable to the geomagnetic field. The magnetic variability is driven by the Lorentz force and is characterized by an inverse correlation between dynamo magnetic and kinetic energy fluctuations. A constant energy dissipation theory accounts for this inverse energy correlation, which is shown to produce conditions favorable for dipole drift, polarity reversals, and excursions. PMID:18048345

  12. Frequency-scanning particle size spectrometer

    NASA Technical Reports Server (NTRS)

    Fymat, A. L. (Inventor)

    1979-01-01

    A particle size spectrometer having a fixed field of view within the forward light scattering cone at an angle theta sub s between approximately 100 and 200 minutes of arc (preferably at 150 minutes), a spectral range extending approximately from 0.2 to 4.0 inverse micrometers, and a spectral resolution between about 0.1 and 0.2 inverse micrometers (preferably toward the lower end of this range of spectral resolution), is employed to determine the distribution of particle sizes, independently of the chemical composition of the particles, from measurements of incident light, at each frequency, sigma (=1/lambda), and scattered light, I(sigma).

  13. Inversion of Qubit Energy Levels in Qubit-Oscillator Circuits in the Deep-Strong-Coupling Regime.

    PubMed

    Yoshihara, F; Fuse, T; Ao, Z; Ashhab, S; Kakuyanagi, K; Saito, S; Aoki, T; Koshino, K; Semba, K

    2018-05-04

    We report on experimentally measured light shifts of superconducting flux qubits deep-strongly coupled to LC oscillators, where the coupling constants are comparable to the qubit and oscillator resonance frequencies. By using two-tone spectroscopy, the energies of the six lowest levels of each circuit are determined. We find huge Lamb shifts that exceed 90% of the bare qubit frequencies and inversions of the qubits' ground and excited states when there are a finite number of photons in the oscillator. Our experimental results agree with theoretical predictions based on the quantum Rabi model.

  14. On increasing stability in the two dimensional inverse source scattering problem with many frequencies

    NASA Astrophysics Data System (ADS)

    Entekhabi, Mozhgan Nora; Isakov, Victor

    2018-05-01

    In this paper, we will study the increasing stability in the inverse source problem for the Helmholtz equation in the plane when the source term is assumed to be compactly supported in a bounded domain Ω with a sufficiently smooth boundary. Using the Fourier transform in the frequency domain, bounds for the Hankel functions and for scattering solutions in the complex plane, improving bounds for the analytic continuation, and the exact observability for the wave equation led us to our goals which are a sharp uniqueness and increasing stability estimate when the wave number interval is growing.

  15. Inversion of Qubit Energy Levels in Qubit-Oscillator Circuits in the Deep-Strong-Coupling Regime

    NASA Astrophysics Data System (ADS)

    Yoshihara, F.; Fuse, T.; Ao, Z.; Ashhab, S.; Kakuyanagi, K.; Saito, S.; Aoki, T.; Koshino, K.; Semba, K.

    2018-05-01

    We report on experimentally measured light shifts of superconducting flux qubits deep-strongly coupled to L C oscillators, where the coupling constants are comparable to the qubit and oscillator resonance frequencies. By using two-tone spectroscopy, the energies of the six lowest levels of each circuit are determined. We find huge Lamb shifts that exceed 90% of the bare qubit frequencies and inversions of the qubits' ground and excited states when there are a finite number of photons in the oscillator. Our experimental results agree with theoretical predictions based on the quantum Rabi model.

  16. Optical and microwave control of resonance fluorescence and squeezing spectra in a polar molecule

    NASA Astrophysics Data System (ADS)

    Antón, M. A.; Maede-Razavi, S.; Carreño, F.; Thanopulos, I.; Paspalakis, E.

    2017-12-01

    A two-level quantum emitter with broken inversion symmetry simultaneously driven by an optical field and a microwave field that couples to the permanent dipole's moment is presented. We focus to a situation where the angular frequency of the microwave field is chosen such that it closely matches the Rabi frequency of the optical field, the so-called Rabi resonance condition. Using a series of unitary transformations we obtain an effective Hamiltonian in the double-dressed basis which results in easily solvable Bloch equations which allow us to derive analytical expressions for the spectrum of the scattered photons. We analyze the steady-state population inversion of the system which shows a distinctive behavior at the Rabi resonance with regard to an ordinary two-level nonpolar system. We show that saturation can be produced even in the case that the optical field is far detuned from the transition frequency, and we demonstrate that this behavior can be controlled through the intensity and the angular frequency of the microwave field. The spectral properties of the scattered photons are analyzed and manifest the emergence of a series of Mollow-like triplets which may be spectrally broadened or narrowed for proper values of the amplitude and/or frequency of the low-frequency field. We also analyze the phase-dependent spectrum which reveals that a significant enhancement or suppression of the squeezing at certain sidebands can be produced. These quantum phenomena are illustrated in a recently synthesized molecular complex with high nonlinear optical response although they can also occur in other quantum systems with broken inversion symmetry.

  17. Patterns of genetic variation across inversions: geographic variation in the In(2L)t inversion in populations of Drosophila melanogaster from eastern Australia.

    PubMed

    Kennington, W Jason; Hoffmann, Ary A

    2013-05-20

    Chromosomal inversions are increasingly being recognized as important in adaptive shifts and are expected to influence patterns of genetic variation, but few studies have examined genetic patterns in inversion polymorphisms across and within populations. Here, we examine genetic variation at 20 microsatellite loci and the alcohol dehydrogenase gene (Adh) located within and near the In(2L)t inversion of Drosophila melanogaster at three different sites along a latitudinal cline on the east coast of Australia. We found significant genetic differentiation between the standard and inverted chromosomal arrangements at each site as well as significant, but smaller differences among sites in the same arrangement. Genetic differentiation between pairs of sites was higher for inverted chromosomes than standard chromosomes, while inverted chromosomes had lower levels of genetic variation even well away from inversion breakpoints. Bayesian clustering analysis provided evidence of genetic exchange between chromosomal arrangements at each site. The strong differentiation between arrangements and reduced variation in the inverted chromosomes are likely to reflect ongoing selection at multiple loci within the inverted region. They may also reflect lower effective population sizes of In(2L)t chromosomes and colonization of Australia, although there was no consistent evidence of a recent bottleneck and simulations suggest that differences between arrangements would not persist unless rates of gene exchange between them were low. Genetic patterns therefore support the notion of selection and linkage disequilibrium contributing to inversion polymorphisms, although more work is needed to determine whether there are spatially varying targets of selection within this inversion. They also support the idea that the allelic content within an inversion can vary between geographic locations.

  18. Double point source W-phase inversion: Real-time implementation and automated model selection

    USGS Publications Warehouse

    Nealy, Jennifer; Hayes, Gavin

    2015-01-01

    Rapid and accurate characterization of an earthquake source is an extremely important and ever evolving field of research. Within this field, source inversion of the W-phase has recently been shown to be an effective technique, which can be efficiently implemented in real-time. An extension to the W-phase source inversion is presented in which two point sources are derived to better characterize complex earthquakes. A single source inversion followed by a double point source inversion with centroid locations fixed at the single source solution location can be efficiently run as part of earthquake monitoring network operational procedures. In order to determine the most appropriate solution, i.e., whether an earthquake is most appropriately described by a single source or a double source, an Akaike information criterion (AIC) test is performed. Analyses of all earthquakes of magnitude 7.5 and greater occurring since January 2000 were performed with extended analyses of the September 29, 2009 magnitude 8.1 Samoa earthquake and the April 19, 2014 magnitude 7.5 Papua New Guinea earthquake. The AIC test is shown to be able to accurately select the most appropriate model and the selected W-phase inversion is shown to yield reliable solutions that match published analyses of the same events.

  19. Fruits, vegetables, soy foods and breast cancer in pre- and postmenopausal Korean women: a case-control study.

    PubMed

    Do, Min Hee; Lee, Sang Sun; Kim, Jung Yun; Jung, Pa Jong; Lee, Min Hyuk

    2007-03-01

    We carried out a case-control study to examine the relationship between fruits, vegetables, and soy foods intake with breast cancer risk in Korean women. Incident cases (n = 359) were identified through cancer biopsies and hospital-based controls (n = 708) were selected in the same hospitals. Subjects were asked to indicate usual dietary habits, which were assessed using a semi-quantitative food frequency questionnaire (98 items). Odds ratio (OR) and 95% confidence intervals (95% CI) were calculated by unconditional logistic regression after adjustment for additional confounding factors according to the menopausal status. High grape intake showed an inverse association of breast cancer in postmenopausal women (OR = 0.59, 95% CI = 0.35-0.95; p for trend = 0.05). High tomato intake was associated with reduced breast cancer risk in premenopausal women (OR = 0.59, 95% CI = 0.38-0.89, p for trend = 0.04). In postmenopausal women, green pepper intake showed an inverse association of breast cancer risk (OR = 0.60, 95% CI = 0.43-0.96, p for trend = 0.03). High soybean intake showed an inverse association of breast cancer in postmenopausal women (OR = 0.61, 95% CI = 0.34-0.89, p for trend = 0.02). Our study suggests that high intake of some fruits, vegetables, and soybeans may be associated with a reduced breast cancer risk.

  20. Estimation of biological parameters of marine organisms using linear and nonlinear acoustic scattering model-based inversion methods.

    PubMed

    Chu, Dezhang; Lawson, Gareth L; Wiebe, Peter H

    2016-05-01

    The linear inversion commonly used in fisheries and zooplankton acoustics assumes a constant inversion kernel and ignores the uncertainties associated with the shape and behavior of the scattering targets, as well as other relevant animal parameters. Here, errors of the linear inversion due to uncertainty associated with the inversion kernel are quantified. A scattering model-based nonlinear inversion method is presented that takes into account the nonlinearity of the inverse problem and is able to estimate simultaneously animal abundance and the parameters associated with the scattering model inherent to the kernel. It uses sophisticated scattering models to estimate first, the abundance, and second, the relevant shape and behavioral parameters of the target organisms. Numerical simulations demonstrate that the abundance, size, and behavior (tilt angle) parameters of marine animals (fish or zooplankton) can be accurately inferred from the inversion by using multi-frequency acoustic data. The influence of the singularity and uncertainty in the inversion kernel on the inversion results can be mitigated by examining the singular values for linear inverse problems and employing a non-linear inversion involving a scattering model-based kernel.

  1. Reflection full-waveform inversion using a modified phase misfit function

    NASA Astrophysics Data System (ADS)

    Cui, Chao; Huang, Jian-Ping; Li, Zhen-Chun; Liao, Wen-Yuan; Guan, Zhe

    2017-09-01

    Reflection full-waveform inversion (RFWI) updates the low- and highwavenumber components, and yields more accurate initial models compared with conventional full-waveform inversion (FWI). However, there is strong nonlinearity in conventional RFWI because of the lack of low-frequency data and the complexity of the amplitude. The separation of phase and amplitude information makes RFWI more linear. Traditional phase-calculation methods face severe phase wrapping. To solve this problem, we propose a modified phase-calculation method that uses the phase-envelope data to obtain the pseudo phase information. Then, we establish a pseudophase-information-based objective function for RFWI, with the corresponding source and gradient terms. Numerical tests verify that the proposed calculation method using the phase-envelope data guarantees the stability and accuracy of the phase information and the convergence of the objective function. The application on a portion of the Sigsbee2A model and comparison with inversion results of the improved RFWI and conventional FWI methods verify that the pseudophase-based RFWI produces a highly accurate and efficient velocity model. Moreover, the proposed method is robust to noise and high frequency.

  2. Numerical solution of a coefficient inverse problem with multi-frequency experimental raw data by a globally convergent algorithm

    NASA Astrophysics Data System (ADS)

    Nguyen, Dinh-Liem; Klibanov, Michael V.; Nguyen, Loc H.; Kolesov, Aleksandr E.; Fiddy, Michael A.; Liu, Hui

    2017-09-01

    We analyze in this paper the performance of a newly developed globally convergent numerical method for a coefficient inverse problem for the case of multi-frequency experimental backscatter data associated to a single incident wave. These data were collected using a microwave scattering facility at the University of North Carolina at Charlotte. The challenges for the inverse problem under the consideration are not only from its high nonlinearity and severe ill-posedness but also from the facts that the amount of the measured data is minimal and that these raw data are contaminated by a significant amount of noise, due to a non-ideal experimental setup. This setup is motivated by our target application in detecting and identifying explosives. We show in this paper how the raw data can be preprocessed and successfully inverted using our inversion method. More precisely, we are able to reconstruct the dielectric constants and the locations of the scattering objects with a good accuracy, without using any advanced a priori knowledge of their physical and geometrical properties.

  3. A method of inversion of satellite magnetic anomaly data

    NASA Technical Reports Server (NTRS)

    Mayhew, M. A.

    1977-01-01

    A method of finding a first approximation to a crustal magnetization distribution from inversion of satellite magnetic anomaly data is described. Magnetization is expressed as a Fourier Series in a segment of spherical shell. Input to this procedure is an equivalent source representation of the observed anomaly field. Instability of the inversion occurs when high frequency noise is present in the input data, or when the series is carried to an excessively high wave number. Preliminary results are given for the United States and adjacent areas.

  4. Identification of Scattering Mechanisms from Measured Impulse Response Signatures of Several Conducting Objects.

    DTIC Science & Technology

    1984-02-01

    conducting sphere 35 compared to inverse transform of exact solution. 4-5. Measured impulse response of a conducting 2:1 right 37 circular cylinder with...frequency domain. This is equivalent to multiplication in the time domain by the inverse transform of w(n), which is shown in Figure 3-1 for N=15. The...equivalent pulse width from 0.066 T for the rectangular window to 0.10 T for the Hanning window. The inverse transform of the Hanning window is shown

  5. Community expansion and gene geography of sickle cell trait and G6PD deficiency, and natural selection against malaria: experience from tribal land of India.

    PubMed

    Balgir, R S

    2012-03-01

    Malaria is globally endemic in tropical and subtropical regions and so is the hemoglobinopathies, thalassemias and glucose-6-phosphate dehydrogenase (G6PD) deficiency. This biological dogma of hyper-endemic all over the tribal land in India leads to high morbidity and mortality. The directed genetic abnormalities of human erythrocytes have found to decrease the susceptibility towards malaria parasites and the heterozygotes of abnormalities probably confer protection against the Plasmodium falciparum infection. A fascinating trend for an inverse relationship between sickle cell disorders and G6PD deficiency in scheduled caste and tribal communities of Central-Eastern India has been observed. When the frequency of sickle cell allele decreases in malaria endemic cross-section of the tribal population, the frequency of G6PD deficiency allele increases and vice versa. This medical aspect is important from an evolutionary biological background and could be an excellent point for molecular analyses to determine the signature of selection in the genomic regions of β- globin and G6PD genes. Since the selection favors the mutation with least cost to the population [as the clinical manifestations of G6PD deficiency are mild and do not result in a complete loss of enzyme activity against the sickle cell disease with high morbidity and mortality in the region] and the predominant frequency of G6PD deficiency over the sickle cell disorders in some tribal communities, it seems that the replacement of sickle cell allele for G6PD deficiency is occurring in the scheduled castes/tribes of Chhattisgarh, Madhya Pradesh, Maharashtra and Odisha states in Central India. These findings are consistent with our previous studies carried out in Central-Eastern India.

  6. Cyclotron-based of plant gravisensing

    NASA Astrophysics Data System (ADS)

    Kordyum, E.; Kalinina, Ia.; Bogatina, N.; Kondrachuk, A.

    Roots exhibit positive gravitropism they grow in the direction of a gravitational vector while shoots respond negatively and grow opposite to a gravitational vector We first demonstrated the inversion of roots gravitropism from positive to negative one under gravistimulation in the weak combined magnetic field WCMF consisted of permanent magnetic field PMF with the magnitude of order of 50 mu T and altering magnetic field AMF with the 6 mu T magnitude and a frequency of 32 Hz It was found that the effect of inversion has a resonance nature It means that in the interval of frequencies 1-45 Hz inversion of root gravitropism occurs only at frequency 32 Hz 2-3-day old cress seedlings were gravistimulated in moist chambers which are placed in mu -metal shields Inside mu -metal shields combined magnetic fields have been created The magnitude of magnetic fields was measured by a flux-gate magnetometer Experiments were performed in darkness at temperature 20 pm 1 0 C We measured the divergence angle of a growing root from its horizontal position After 1 h of gravistimulation in the WCMF we observed negative gravitropism of cress roots i e they grow in the opposite direction to a gravitational vector Frequency of 32 Hz for the magnitude of the PMF applied formally corresponds to cyclotron frequency of Ca 2 ions This indicates possible participation of calcium ions in root gravitropism There are many evidences of resonance effects of the WCMF on the biological processes that involve Ca 2 but the nature of

  7. Shear wave velocity and attenuation in the upper layer of ocean bottoms from long-range acoustic field measurements.

    PubMed

    Zhou, Ji-Xun; Zhang, Xue-Zhen

    2012-12-01

    Several physics-based seabed geoacoustic models (including the Biot theory) predict that compressional wave attenuation α(2) in sandy marine sediments approximately follows quadratic frequency dependence at low frequencies, i.e., α(2)≈kf(n) (dB/m), n=2. A recent paper on broadband geoacoustic inversions from low frequency (LF) field measurements, made at 20 locations around the world, has indicated that the frequency exponent of the effective sound attenuation n≈1.80 in a frequency band of 50-1000 Hz [Zhou et al., J. Acoust. Soc. Am. 125, 2847-2866 (2009)]. Carey and Pierce hypothesize that the discrepancy is due to the inversion models' neglect of shear wave effects [J. Acoust. Soc. Am. 124, EL271-EL277 (2008)]. The broadband geoacoustic inversions assume that the seabottom is an equivalent fluid and sound waves interact with the bottom at small grazing angles. The shear wave velocity and attenuation in the upper layer of ocean bottoms are estimated from the LF field-inverted effective bottom attenuations using a near-grazing bottom reflection expression for the equivalent fluid model, derived by Zhang and Tindle [J. Acoust. Soc. Am. 98, 3391-3396 (1995)]. The resultant shear wave velocity and attenuation are consistent with the SAX99 measurement at 25 Hz and 1000 Hz. The results are helpful for the analysis of shear wave effects on long-range sound propagation in shallow water.

  8. Wedge-shaped slice-selective adiabatic inversion pulse for controlling temporal width of bolus in pulsed arterial spin labeling

    PubMed Central

    Guo, Jia; Buxton, Richard B.; Wong, Eric C.

    2015-01-01

    Purpose In pulsed arterial spin labeling (PASL) methods, arterial blood is labeled via inverting a slab with uniform thickness, resulting in different temporal widths of boluses in vessels with different flow velocities. This limits the temporal resolution and signal-to-noise ratio (SNR) efficiency gains in PASL-based methods intended for high temporal resolution and SNR efficiency, such as Turbo-ASL and Turbo-QUASAR. Theory and Methods A novel wedge-shaped (WS) adiabatic inversion pulse is developed by adding in-plane gradient pulses to a slice-selective (SS) adiabatic inversion pulse to linearly modulate the inversion thicknesses at different locations while maintaining the adiabatic properties of the original pulse. A hyperbolic secant (HS) based WS inversion pulse was implemented. Its performance was tested in simulations, phantom and human experiments, and compared to an SS HS inversion pulse. Results Compared to the SS inversion pulse, the WS inversion pulse is capable of inducing different inversion thicknesses at different locations. It can be adjusted to generate a uniform temporal width of boluses in arteries at locations with different flow velocities. Conclusion The WS inversion pulse can be used to control the temporal widths of labeled boluses in PASL experiments. This should benefit PASL experiments by maximizing labeling duty cycle, and improving temporal resolution and SNR efficiency. PMID:26451521

  9. Forward modeling and inversion of tensor CSAMT in 3D anisotropic media

    NASA Astrophysics Data System (ADS)

    Wang, Tao; Wang, Kun-Peng; Tan, Han-Dong

    2017-12-01

    Tensor controlled-source audio-frequency magnetotellurics (CSAMT) can yield information about electric and magnetic fields owing to its multi-transmitter configuration compared with the common scalar CSAMT. The most current theories, numerical simulations, and inversion of tensor CSAMT are based on far-field measurements and the assumption that underground media have isotropic resistivity. We adopt a three-dimensional (3D) staggered-grid finite difference numerical simulation method to analyze the resistivity in axial anisotropic and isotropic media. We further adopt the limited-memory Broyden-Fletcher-Goldfarb-Shanno (LBFGS) method to perform 3D tensor CSAMT axial anisotropic inversion. The inversion results suggest that when the underground structure is anisotropic, the isotropic inversion will introduce errors to the interpretation.

  10. A time domain inverse dynamic method for the end point tracking control of a flexible manipulator

    NASA Technical Reports Server (NTRS)

    Kwon, Dong-Soo; Book, Wayne J.

    1991-01-01

    The inverse dynamic equation of a flexible manipulator was solved in the time domain. By dividing the inverse system equation into the causal part and the anticausal part, we calculated the torque and the trajectories of all state variables for a given end point trajectory. The interpretation of this method in the frequency domain was explained in detail using the two-sided Laplace transform and the convolution integral. The open loop control of the inverse dynamic method shows an excellent result in simulation. For real applications, a practical control strategy is proposed by adding a feedback tracking control loop to the inverse dynamic feedforward control, and its good experimental performance is presented.

  11. Inverse cascades and resonant triads in rotating and stratified turbulence

    NASA Astrophysics Data System (ADS)

    Oks, D.; Mininni, P. D.; Marino, R.; Pouquet, A.

    2017-11-01

    Kraichnan's seminal ideas on inverse cascades yielded new tools to study common phenomena in geophysical turbulent flows. In the atmosphere and the oceans, rotation and stratification result in a flow that can be approximated as two-dimensional at very large scales but which requires considering three-dimensional effects to fully describe turbulent transport processes and non-linear phenomena. Motions can thus be classified into two classes: fast modes consisting of inertia-gravity waves and slow quasi-geostrophic modes for which the Coriolis force and horizontal pressure gradients are close to balance. In this paper, we review previous results on the strength of the inverse cascade in rotating and stratified flows and then present new results on the effect of varying the strength of rotation and stratification (measured by the inverse Prandtl ratio N/f, of the Coriolis frequency to the Brunt-Väisäla frequency) on the amplitude of the waves and on the flow quasi-geostrophic behavior. We show that the inverse cascade is more efficient in the range of N/f for which resonant triads do not exist, 1 /2 ≤N /f ≤2 . We then use the spatio-temporal spectrum to show that in this range slow modes dominate the dynamics, while the strength of the waves (and their relevance in the flow dynamics) is weaker.

  12. Low frequency full waveform seismic inversion within a tree based Bayesian framework

    NASA Astrophysics Data System (ADS)

    Ray, Anandaroop; Kaplan, Sam; Washbourne, John; Albertin, Uwe

    2018-01-01

    Limited illumination, insufficient offset, noisy data and poor starting models can pose challenges for seismic full waveform inversion. We present an application of a tree based Bayesian inversion scheme which attempts to mitigate these problems by accounting for data uncertainty while using a mildly informative prior about subsurface structure. We sample the resulting posterior model distribution of compressional velocity using a trans-dimensional (trans-D) or Reversible Jump Markov chain Monte Carlo method in the wavelet transform domain of velocity. This allows us to attain rapid convergence to a stationary distribution of posterior models while requiring a limited number of wavelet coefficients to define a sampled model. Two synthetic, low frequency, noisy data examples are provided. The first example is a simple reflection + transmission inverse problem, and the second uses a scaled version of the Marmousi velocity model, dominated by reflections. Both examples are initially started from a semi-infinite half-space with incorrect background velocity. We find that the trans-D tree based approach together with parallel tempering for navigating rugged likelihood (i.e. misfit) topography provides a promising, easily generalized method for solving large-scale geophysical inverse problems which are difficult to optimize, but where the true model contains a hierarchy of features at multiple scales.

  13. Non-perturbational surface-wave inversion: A Dix-type relation for surface waves

    USGS Publications Warehouse

    Haney, Matt; Tsai, Victor C.

    2015-01-01

    We extend the approach underlying the well-known Dix equation in reflection seismology to surface waves. Within the context of surface wave inversion, the Dix-type relation we derive for surface waves allows accurate depth profiles of shear-wave velocity to be constructed directly from phase velocity data, in contrast to perturbational methods. The depth profiles can subsequently be used as an initial model for nonlinear inversion. We provide examples of the Dix-type relation for under-parameterized and over-parameterized cases. In the under-parameterized case, we use the theory to estimate crustal thickness, crustal shear-wave velocity, and mantle shear-wave velocity across the Western U.S. from phase velocity maps measured at 8-, 20-, and 40-s periods. By adopting a thin-layer formalism and an over-parameterized model, we show how a regularized inversion based on the Dix-type relation yields smooth depth profiles of shear-wave velocity. In the process, we quantitatively demonstrate the depth sensitivity of surface-wave phase velocity as a function of frequency and the accuracy of the Dix-type relation. We apply the over-parameterized approach to a near-surface data set within the frequency band from 5 to 40 Hz and find overall agreement between the inverted model and the result of full nonlinear inversion.

  14. 2D joint inversion of CSAMT and magnetic data based on cross-gradient theory

    NASA Astrophysics Data System (ADS)

    Wang, Kun-Peng; Tan, Han-Dong; Wang, Tao

    2017-06-01

    A two-dimensional forward and backward algorithm for the controlled-source audio-frequency magnetotelluric (CSAMT) method is developed to invert data in the entire region (near, transition, and far) and deal with the effects of artificial sources. First, a regularization factor is introduced in the 2D magnetic inversion, and the magnetic susceptibility is updated in logarithmic form so that the inversion magnetic susceptibility is always positive. Second, the joint inversion of the CSAMT and magnetic methods is completed with the introduction of the cross gradient. By searching for the weight of the cross-gradient term in the objective function, the mutual influence between two different physical properties at different locations are avoided. Model tests show that the joint inversion based on cross-gradient theory offers better results than the single-method inversion. The 2D forward and inverse algorithm for CSAMT with source can effectively deal with artificial sources and ensures the reliability of the final joint inversion algorithm.

  15. WISDOM : an UHF GPR on the Exomars Mission

    NASA Astrophysics Data System (ADS)

    Corbel, C.; Hamram, S.; Ney, R.; Plettemeier, D.; Dolon, F.; Jeangeot, A.; Ciarletti, V.; Berthelier, J.

    2006-12-01

    This paper describes the main technical features of WISDOM (Water Ice and Subsurface Deposit Observations on Mars) Ground Penetrating Radar. This radar has been selected on the PASTEUR payload of the ESA ExoMars rover. The launch is scheduled in 2011. The main objective of this mission is to acquire and analyze samples of the shallow subsurface and search for traces of extinct or extant life. The WISDOM GPR aims at providing observations of the structure and layering of the upper layers of the subsurface in order to retrieve geological information that are of prime interest to select optimal sites to drill. It will also localize buried obstacles (rocks, boulders, ?)in the underground that will make the delicate drilling operations safer. WISDOM will operate in the UHF range from 500 MHz to 3 GHz and probe the first few meters of the subsurface with a high resolution (a few centimeters). The large bandwidth requirement (2.5 GHz) led us to select a gated step frequency technique for WISDOM. The Step Frequency technique is based on the analysis of the system in the frequency domain. The phase and amplitude of the reflected signal are measured at about 200 different frequencies effectively measuring the transfer function of the sub-surface between the transmitter and receiver antenna. The impulse response and eventually the distance of the reflecting structures can be obtained by performing an inverse Fourier transform of the measured transfer function. The broad band antennas have been designed in order to have a wide radiation pattern into the sub-surface and to avoid the direct coupling and allow co and cross polar measurements. To decrease the direct signal between the transmitter and the receiver or strong reflections from the surface, hardware range gating is implemented. The performances of the instrument operated in well characterized conditions will be presented

  16. Efficient calculation of full waveform time domain inversion for electromagnetic problem using fictitious wave domain method and cascade decimation decomposition

    NASA Astrophysics Data System (ADS)

    Imamura, N.; Schultz, A.

    2016-12-01

    Recently, a full waveform time domain inverse solution has been developed for the magnetotelluric (MT) and controlled-source electromagnetic (CSEM) methods. The ultimate goal of this approach is to obtain a computationally tractable direct waveform joint inversion to solve simultaneously for source fields and earth conductivity structure in three and four dimensions. This is desirable on several grounds, including the improved spatial resolving power expected from use of a multitude of source illuminations, the ability to operate in areas of high levels of source signal spatial complexity, and non-stationarity. This goal would not be obtainable if one were to adopt the pure time domain solution for the inverse problem. This is particularly true for the case of MT surveys, since an enormous number of degrees of freedom are required to represent the observed MT waveforms across a large frequency bandwidth. This means that for the forward simulation, the smallest time steps should be finer than that required to represent the highest frequency, while the number of time steps should also cover the lowest frequency. This leads to a sensitivity matrix that is computationally burdensome to solve a model update. We have implemented a code that addresses this situation through the use of cascade decimation decomposition to reduce the size of the sensitivity matrix substantially, through quasi-equivalent time domain decomposition. We also use a fictitious wave domain method to speed up computation time of the forward simulation in the time domain. By combining these refinements, we have developed a full waveform joint source field/earth conductivity inverse modeling method. We found that cascade decimation speeds computations of the sensitivity matrices dramatically, keeping the solution close to that of the undecimated case. For example, for a model discretized into 2.6x105 cells, we obtain model updates in less than 1 hour on a 4U rack-mounted workgroup Linux server, which is a practical computational time for the inverse problem.

  17. Phase and amplitude inversion of crosswell radar data

    USGS Publications Warehouse

    Ellefsen, Karl J.; Mazzella, Aldo T.; Horton, Robert J.; McKenna, Jason R.

    2011-01-01

    Phase and amplitude inversion of crosswell radar data estimates the logarithm of complex slowness for a 2.5D heterogeneous model. The inversion is formulated in the frequency domain using the vector Helmholtz equation. The objective function is minimized using a back-propagation method that is suitable for a 2.5D model and that accounts for the near-, intermediate-, and far-field regions of the antennas. The inversion is tested with crosswell radar data collected in a laboratory tank. The model anomalies are consistent with the known heterogeneity in the tank; the model’s relative dielectric permittivity, which is calculated from the real part of the estimated complex slowness, is consistent with independent laboratory measurements. The methodologies developed for this inversion can be adapted readily to inversions of seismic data (e.g., crosswell seismic and vertical seismic profiling data).

  18. Simultaneous displacement and slope measurement in electronic speckle pattern interferometry using adjustable aperture multiplexing.

    PubMed

    Lu, Min; Wang, Shengjia; Aulbach, Laura; Koch, Alexander W

    2016-08-01

    This paper suggests the use of adjustable aperture multiplexing (AAM), a method which is able to introduce multiple tunable carrier frequencies into a three-beam electronic speckle pattern interferometer to measure the out-of-plane displacement and its first-order derivative simultaneously. In the optical arrangement, two single apertures are located in the object and reference light paths, respectively. In cooperation with two adjustable mirrors, virtual images of the single apertures construct three pairs of virtual double apertures with variable aperture opening sizes and aperture distances. By setting the aperture parameter properly, three tunable spatial carrier frequencies are produced within the speckle pattern and completely separate the information of three interferograms in the frequency domain. By applying the inverse Fourier transform to a selected spectrum, its corresponding phase difference distribution can thus be evaluated. Therefore, we can obtain the phase map due to the deformation as well as its slope of the test surface from two speckle patterns which are recorded at different loading events. By this means, simultaneous and dynamic measurements are realized. AAM has greatly simplified the measurement system, which contributes to improving the system stability and increasing the system flexibility and adaptability to various measurement requirements. This paper presents the AAM working principle, the phase retrieval using spatial carrier frequency, and preliminary experimental results.

  19. Sinc or Sine? The Band Excitation Method and Energy Dissipation Measurements by SPM

    NASA Astrophysics Data System (ADS)

    Jesse, Stephen; Kalinin, Sergei

    2007-03-01

    Quantitative energy dissipation measurements in force-based SPM is the key to understanding fundamental mechanisms of energy transformations on the nanoscale, molecular, and atomic levels. To date, these measurements are invariably based on either phase and amplitude detection in constant frequency mode, or as amplitude detection in frequency-tracking mode. The analysis in both cases implicitly assumes that amplitude is inversely proportional to the Q-factor and is not applicable when the driving force is position dependent, as is the case for virtually all SPM measurements. All current SPM methods sample only a single frequency in the Fourier domain of the system. Thus, only two out of three parameters (amplitude, resonance, and Q) can be determined independently. Here, we developed and implemented a new approach for SPM detection based on the excitation and detection of a signal having a finite amplitude over a selected region in the Fourier domain and allows simultaneous determination of all three parameters. This band excitation method allows acquisition of the local spectral response at a 10ms/pixel rate, compatible with fast imaging, and is illustrated for electromechanical and mechanical imaging and force-distance spectroscopy. The BE method thus represents a new paradigm in SPM, beyond traditional single-frequency excitation.

  20. Finite frequency shear wave splitting tomography: a model space search approach

    NASA Astrophysics Data System (ADS)

    Mondal, P.; Long, M. D.

    2017-12-01

    Observations of seismic anisotropy provide key constraints on past and present mantle deformation. A common method for upper mantle anisotropy is to measure shear wave splitting parameters (delay time and fast direction). However, the interpretation is not straightforward, because splitting measurements represent an integration of structure along the ray path. A tomographic approach that allows for localization of anisotropy is desirable; however, tomographic inversion for anisotropic structure is a daunting task, since 21 parameters are needed to describe general anisotropy. Such a large parameter space does not allow a straightforward application of tomographic inversion. Building on previous work on finite frequency shear wave splitting tomography, this study aims to develop a framework for SKS splitting tomography with a new parameterization of anisotropy and a model space search approach. We reparameterize the full elastic tensor, reducing the number of parameters to three (a measure of strength based on symmetry considerations for olivine, plus the dip and azimuth of the fast symmetry axis). We compute Born-approximation finite frequency sensitivity kernels relating model perturbations to splitting intensity observations. The strong dependence of the sensitivity kernels on the starting anisotropic model, and thus the strong non-linearity of the inverse problem, makes a linearized inversion infeasible. Therefore, we implement a Markov Chain Monte Carlo technique in the inversion procedure. We have performed tests with synthetic data sets to evaluate computational costs and infer the resolving power of our algorithm for synthetic models with multiple anisotropic layers. Our technique can resolve anisotropic parameters on length scales of ˜50 km for realistic station and event configurations for dense broadband experiments. We are proceeding towards applications to real data sets, with an initial focus on the High Lava Plains of Oregon.

  1. Electrokinetic energy conversion efficiency of viscoelastic fluids in a polyelectrolyte-grafted nanochannel.

    PubMed

    Jian, Yongjun; Li, Fengqin; Liu, Yongbo; Chang, Long; Liu, Quansheng; Yang, Liangui

    2017-08-01

    In order to conduct extensive investigation of energy harvesting capabilities of nanofluidic devices, we provide analytical solutions for streaming potential and electrokinetic energy conversion (EKEC) efficiency through taking the combined consequences of soft nanochannel, a rigid nanochannel whose surface is covered by charged polyelectrolyte layer, and viscoelastic rheology into account. The viscoelasticity of the fluid is considered by employing the Maxwell constitutive model when the forcing frequency of an oscillatory driving pressure flow matches with the inverse of the relaxation time scale of a typical viscoelastic fluid. We compare the streaming potential and EKEC efficiency with those of a rigid nanochannel, having zeta potential equal to the electrostatic potential at the solid-polyelectrolyte interface of the soft nanochannels. Within the present selected parameter ranges, it is shown that the different peaks of maximal streaming potential and EKEC efficiency for the rigid nanochannel are larger than those for the soft nanochannel when forcing frequencies of the driving pressure gradient are close to resonating frequencies. However, more enhanced streaming potential and EKEC efficiency for a soft nanochannel can be found in most of the regions away from these resonant frequencies. Moreover, the influence of several dimensionless parameters on EKEC efficiency is discussed in detail. Finally, within the given parametric regions, the maximum efficiency at some resonant frequency obtained in present analysis is about 25%. Copyright © 2017 Elsevier B.V. All rights reserved.

  2. Selected inversion as key to a stable Langevin evolution across the QCD phase boundary

    NASA Astrophysics Data System (ADS)

    Bloch, Jacques; Schenk, Olaf

    2018-03-01

    We present new results of full QCD at nonzero chemical potential. In PRD 92, 094516 (2015) the complex Langevin method was shown to break down when the inverse coupling decreases and enters the transition region from the deconfined to the confined phase. We found that the stochastic technique used to estimate the drift term can be very unstable for indefinite matrices. This may be avoided by using the full inverse of the Dirac operator, which is, however, too costly for four-dimensional lattices. The major breakthrough in this work was achieved by realizing that the inverse elements necessary for the drift term can be computed efficiently using the selected inversion technique provided by the parallel sparse direct solver package PARDISO. In our new study we show that no breakdown of the complex Langevin method is encountered and that simulations can be performed across the phase boundary.

  3. Improved fat-suppression homogeneity with mDIXON turbo spin echo (TSE) in pediatric spine imaging at 3.0 T.

    PubMed

    Pokorney, Amber L; Chia, Jonathan M; Pfeifer, Cory M; Miller, Jeffrey H; Hu, Houchun H

    2017-11-01

    Background Robust fat suppression remains essential in clinical MRI to improve tissue signal contrast, minimize fat-related artifacts, and enhance image quality. Purpose To compare fat suppression between mDIXON turbo spin echo (TSE) and conventional frequency-selective and inversion-recovery methods in pediatric spine MRI. Material and Methods Images from T1-weighted (T1W) and T2-weighted (T2W) TSE sequences coupled with conventional methods and the mDIXON technique were compared in 36 patients (5.8 ± 5.4 years) at 3.0 T. Images from 42 pairs of T1W (n = 16) and T2W (n = 26) scans were acquired. Two radiologists reviewed the data and rated images using a three-point scale in two categories, including the uniformity of fat suppression and overall diagnostic image quality. The Wilcoxon rank-sum test was used to compare the scores. Results The Cohen's kappa coefficient for inter-rater agreement was 0.69 (95% confidence interval [CI], 0.56-0.83). Images from mDIXON TSE were considered superior in fat suppression ( P < 0.01) in 22 (rater 1) and 25 (rater 2) cases, respectively. In 13 (rater 1) and 11 (rater 2) cases, mDIXON TSE demonstrated improved diagnostic image quality ( P < 0.01). In three cases, fat suppression was superior using inversion-recovery and likewise in one case mDIXON had poorer image diagnostic quality. Lastly, mDIXON and conventional fat-suppression methods performed similarly in 17 (rater 1) and 14 (rater 2) cases, and yielded equal diagnostic image quality in 28 (rater 1) and 30 (rater 2) cases. Conclusion Robust fat suppression can be achieved with mDixon TSE pediatric spine imaging at 3.0 T and should be considered as a permanent replacement of traditional methods, in particular frequency-selective techniques.

  4. Soy Food Intake and Circulating Levels of Inflammatory Markers in Chinese Women

    PubMed Central

    Wu, Sheng Hui; Shu, Xiao Ou; Chow, Wong-Ho; Xiang, Yong-Bing; Zhang, Xianglan; Li, Hong-Lan; Cai, Qiuyin; Ji, Bu-Tian; Cai, Hui; Rothman, Nathaniel; Gao, Yu-Tang; Zheng, Wei; Yang, Gong

    2013-01-01

    Background Soy and some of its constituents, such as isoflavones, have been shown to affect the inflammatory process in animal studies. The association between soy food intake and inflammatory markers has not been evaluated adequately in humans. Objective Our aim was to evaluate whether higher intake of soy foods was inversely associated with inflammatory markers in 1,005 middle-aged Chinese women. Design In this cross-sectional study, dietary intake of soy foods was assessed by a validated food frequency questionnaire and by a 24-hour recall when biospecimens were procured. A general linear model was used to estimate the geometric means of selected inflammatory markers, including interleukin-6 (IL-6), IL-1β, tumor necrosis factor-α (TNFα), soluble IL-6 receptor, soluble GP130, soluble TNF receptors 1 and 2, and C-reactive protein, across categories of soy food intake after adjusting for age, lifestyle and dietary factors, and history of infectious or inflammation-related diseases. Results We found that multivariable-adjusted geometric mean concentrations of IL-6 and TNFα were inversely associated with quintiles of soy food intake, with a difference between the highest and lowest quintiles of 25.5% for IL-6 (P for trend = 0.008) and 14% for TNFα (P for trend = 0.04). Similar inverse associations were found for TNFα (P for trend = 0.003), soluble TNF receptor 1 (P for trend=0.01), soluble TNF receptor 2 (P for trend=0.02), IL-1β (P for trend=0.05), and IL-6 (P for trend=0.04) when soy food consumption was assessed by the frequency of consumption in the preceding 24 hours. No significant associations were found for other markers studied. Conclusions This study suggests that soy food consumption is related to lower circulating levels of IL-6, TNFα, and soluble TNF receptors 1 and 2 in Chinese women. PMID:22889631

  5. Valley-controlled propagation of pseudospin states in bulk metacrystal waveguides

    NASA Astrophysics Data System (ADS)

    Chen, Xiao-Dong; Deng, Wei-Min; Lu, Jin-Cheng; Dong, Jian-Wen

    2018-05-01

    Light manipulations such as spin-direction locking propagation, robust transport, quantum teleportation, and reconfigurable electromagnetic pathways have been investigated at the boundaries of photonic systems. Recently by breaking Dirac cones in time-reversal-invariant photonic crystals, valley-pseudospin coupled edge states have been employed to realize selective propagation of light. Here, we realize the controllable propagation of pseudospin states in three-dimensional bulk metacrystal waveguides by valley degree of freedom. Reconfigurable photonic valley Hall effect is achieved for frequency-direction locking propagation in such a way that the propagation path can be tunable precisely by scanning the working frequency. A complete transition diagram is illustrated on the valley-dependent pseudospin states of Dirac-cone-absent photonic bands. A photonic blocker is proposed by cascading two inversion asymmetric metacrystal waveguides in which pseudospin-direction locking propagation exists. In addition, valley-dependent pseudospin bands are also discussed in a realistic metamaterials sample. These results show an alternative way toward molding the pseudospin flow in photonic systems.

  6. An Efficient Audio Watermarking Algorithm in Frequency Domain for Copyright Protection

    NASA Astrophysics Data System (ADS)

    Dhar, Pranab Kumar; Khan, Mohammad Ibrahim; Kim, Cheol-Hong; Kim, Jong-Myon

    Digital Watermarking plays an important role for copyright protection of multimedia data. This paper proposes a new watermarking system in frequency domain for copyright protection of digital audio. In our proposed watermarking system, the original audio is segmented into non-overlapping frames. Watermarks are then embedded into the selected prominent peaks in the magnitude spectrum of each frame. Watermarks are extracted by performing the inverse operation of watermark embedding process. Simulation results indicate that the proposed watermarking system is highly robust against various kinds of attacks such as noise addition, cropping, re-sampling, re-quantization, MP3 compression, and low-pass filtering. Our proposed watermarking system outperforms Cox's method in terms of imperceptibility, while keeping comparable robustness with the Cox's method. Our proposed system achieves SNR (signal-to-noise ratio) values ranging from 20 dB to 28 dB, in contrast to Cox's method which achieves SNR values ranging from only 14 dB to 23 dB.

  7. Multifocus image fusion scheme based on the multiscale curvature in nonsubsampled contourlet transform domain

    NASA Astrophysics Data System (ADS)

    Li, Xiaosong; Li, Huafeng; Yu, Zhengtao; Kong, Yingchun

    2015-07-01

    An efficient multifocus image fusion scheme in nonsubsampled contourlet transform (NSCT) domain is proposed. Based on the property of optical imaging and the theory of defocused image, we present a selection principle for lowpass frequency coefficients and also investigate the connection between a low-frequency image and the defocused image. Generally, the NSCT algorithm decomposes detail image information indwells in different scales and different directions in the bandpass subband coefficient. In order to correctly pick out the prefused bandpass directional coefficients, we introduce multiscale curvature, which not only inherits the advantages of windows with different sizes, but also correctly recognizes the focused pixels from source images, and then develop a new fusion scheme of the bandpass subband coefficients. The fused image can be obtained by inverse NSCT with the different fused coefficients. Several multifocus image fusion methods are compared with the proposed scheme. The experimental results clearly indicate the validity and superiority of the proposed scheme in terms of both the visual qualities and the quantitative evaluation.

  8. Efficient computational methods for electromagnetic imaging with applications to 3D magnetotellurics

    NASA Astrophysics Data System (ADS)

    Kordy, Michal Adam

    The motivation for this work is the forward and inverse problem for magnetotellurics, a frequency domain electromagnetic remote-sensing geophysical method used in mineral, geothermal, and groundwater exploration. The dissertation consists of four papers. In the first paper, we prove the existence and uniqueness of a representation of any vector field in H(curl) by a vector lying in H(curl) and H(div). It allows us to represent electric or magnetic fields by another vector field, for which nodal finite element approximation may be used in the case of non-constant electromagnetic properties. With this approach, the system matrix does not become ill-posed for low-frequency. In the second paper, we consider hexahedral finite element approximation of an electric field for the magnetotelluric forward problem. The near-null space of the system matrix for low frequencies makes the numerical solution unstable in the air. We show that the proper solution may obtained by applying a correction on the null space of the curl. It is done by solving a Poisson equation using discrete Helmholtz decomposition. We parallelize the forward code on multicore workstation with large RAM. In the next paper, we use the forward code in the inversion. Regularization of the inversion is done by using the second norm of the logarithm of conductivity. The data space Gauss-Newton approach allows for significant savings in memory and computational time. We show the efficiency of the method by considering a number of synthetic inversions and we apply it to real data collected in Cascade Mountains. The last paper considers a cross-frequency interpolation of the forward response as well as the Jacobian. We consider Pade approximation through model order reduction and rational Krylov subspace. The interpolating frequencies are chosen adaptively in order to minimize the maximum error of interpolation. Two error indicator functions are compared. We prove a theorem of almost always lucky failure in the case of the right hand analytically dependent on frequency. The operator's null space is treated by decomposing the solution into the part in the null space and orthogonal to it.

  9. Full waveform inversion using envelope-based global correlation norm

    NASA Astrophysics Data System (ADS)

    Oh, Ju-Won; Alkhalifah, Tariq

    2018-05-01

    To increase the feasibility of full waveform inversion on real data, we suggest a new objective function, which is defined as the global correlation of the envelopes of modelled and observed data. The envelope-based global correlation norm has the advantage of the envelope inversion that generates artificial low-frequency information, which provides the possibility to recover long-wavelength structure in an early stage. In addition, the envelope-based global correlation norm maintains the advantage of the global correlation norm, which reduces the sensitivity of the misfit to amplitude errors so that the performance of inversion on real data can be enhanced when the exact source wavelet is not available and more complex physics are ignored. Through the synthetic example for 2-D SEG/EAGE overthrust model with inaccurate source wavelet, we compare the performance of four different approaches, which are the least-squares waveform inversion, least-squares envelope inversion, global correlation norm and envelope-based global correlation norm. Finally, we apply the envelope-based global correlation norm on the 3-D Ocean Bottom Cable (OBC) data from the North Sea. The envelope-based global correlation norm captures the strong reflections from the high-velocity caprock and generates artificial low-frequency reflection energy that helps us recover long-wavelength structure of the model domain in the early stages. From this long-wavelength model, the conventional global correlation norm is sequentially applied to invert for higher-resolution features of the model.

  10. 3D CSEM inversion based on goal-oriented adaptive finite element method

    NASA Astrophysics Data System (ADS)

    Zhang, Y.; Key, K.

    2016-12-01

    We present a parallel 3D frequency domain controlled-source electromagnetic inversion code name MARE3DEM. Non-linear inversion of observed data is performed with the Occam variant of regularized Gauss-Newton optimization. The forward operator is based on the goal-oriented finite element method that efficiently calculates the responses and sensitivity kernels in parallel using a data decomposition scheme where independent modeling tasks contain different frequencies and subsets of the transmitters and receivers. To accommodate complex 3D conductivity variation with high flexibility and precision, we adopt the dual-grid approach where the forward mesh conforms to the inversion parameter grid and is adaptively refined until the forward solution converges to the desired accuracy. This dual-grid approach is memory efficient, since the inverse parameter grid remains independent from fine meshing generated around the transmitter and receivers by the adaptive finite element method. Besides, the unstructured inverse mesh efficiently handles multiple scale structures and allows for fine-scale model parameters within the region of interest. Our mesh generation engine keeps track of the refinement hierarchy so that the map of conductivity and sensitivity kernel between the forward and inverse mesh is retained. We employ the adjoint-reciprocity method to calculate the sensitivity kernels which establish a linear relationship between changes in the conductivity model and changes in the modeled responses. Our code uses a direcy solver for the linear systems, so the adjoint problem is efficiently computed by re-using the factorization from the primary problem. Further computational efficiency and scalability is obtained in the regularized Gauss-Newton portion of the inversion using parallel dense matrix-matrix multiplication and matrix factorization routines implemented with the ScaLAPACK library. We show the scalability, reliability and the potential of the algorithm to deal with complex geological scenarios by applying it to the inversion of synthetic marine controlled source EM data generated for a complex 3D offshore model with significant seafloor topography.

  11. 2-D traveltime and waveform inversion for improved seismic imaging: Naga Thrust and Fold Belt, India

    NASA Astrophysics Data System (ADS)

    Jaiswal, Priyank; Zelt, Colin A.; Bally, Albert W.; Dasgupta, Rahul

    2008-05-01

    Exploration along the Naga Thrust and Fold Belt in the Assam province of Northeast India encounters geological as well as logistic challenges. Drilling for hydrocarbons, traditionally guided by surface manifestations of the Naga thrust fault, faces additional challenges in the northeast where the thrust fault gradually deepens leaving subtle surface expressions. In such an area, multichannel 2-D seismic data were collected along a line perpendicular to the trend of the thrust belt. The data have a moderate signal-to-noise ratio and suffer from ground roll and other acquisition-related noise. In addition to data quality, the complex geology of the thrust belt limits the ability of conventional seismic processing to yield a reliable velocity model which in turn leads to poor subsurface image. In this paper, we demonstrate the application of traveltime and waveform inversion as supplements to conventional seismic imaging and interpretation processes. Both traveltime and waveform inversion utilize the first arrivals that are typically discarded during conventional seismic processing. As a first step, a smooth velocity model with long wavelength characteristics of the subsurface is estimated through inversion of the first-arrival traveltimes. This velocity model is then used to obtain a Kirchhoff pre-stack depth-migrated image which in turn is used for the interpretation of the fault. Waveform inversion is applied to the central part of the seismic line to a depth of ~1 km where the quality of the migrated image is poor. Waveform inversion is performed in the frequency domain over a series of iterations, proceeding from low to high frequency (11-19 Hz) using the velocity model from traveltime inversion as the starting model. In the end, the pre-stack depth-migrated image and the waveform inversion model are jointly interpreted. This study demonstrates that a combination of traveltime and waveform inversion with Kirchhoff pre-stack depth migration is a promising approach for the interpretation of geological structures in a thrust belt.

  12. MARE2DEM: a 2-D inversion code for controlled-source electromagnetic and magnetotelluric data

    NASA Astrophysics Data System (ADS)

    Key, Kerry

    2016-10-01

    This work presents MARE2DEM, a freely available code for 2-D anisotropic inversion of magnetotelluric (MT) data and frequency-domain controlled-source electromagnetic (CSEM) data from onshore and offshore surveys. MARE2DEM parametrizes the inverse model using a grid of arbitrarily shaped polygons, where unstructured triangular or quadrilateral grids are typically used due to their ease of construction. Unstructured grids provide significantly more geometric flexibility and parameter efficiency than the structured rectangular grids commonly used by most other inversion codes. Transmitter and receiver components located on topographic slopes can be tilted parallel to the boundary so that the simulated electromagnetic fields accurately reproduce the real survey geometry. The forward solution is implemented with a goal-oriented adaptive finite-element method that automatically generates and refines unstructured triangular element grids that conform to the inversion parameter grid, ensuring accurate responses as the model conductivity changes. This dual-grid approach is significantly more efficient than the conventional use of a single grid for both the forward and inverse meshes since the more detailed finite-element meshes required for accurate responses do not increase the memory requirements of the inverse problem. Forward solutions are computed in parallel with a highly efficient scaling by partitioning the data into smaller independent modeling tasks consisting of subsets of the input frequencies, transmitters and receivers. Non-linear inversion is carried out with a new Occam inversion approach that requires fewer forward calls. Dense matrix operations are optimized for memory and parallel scalability using the ScaLAPACK parallel library. Free parameters can be bounded using a new non-linear transformation that leaves the transformed parameters nearly the same as the original parameters within the bounds, thereby reducing non-linear smoothing effects. Data balancing normalization weights for the joint inversion of two or more data sets encourages the inversion to fit each data type equally well. A synthetic joint inversion of marine CSEM and MT data illustrates the algorithm's performance and parallel scaling on up to 480 processing cores. CSEM inversion of data from the Middle America Trench offshore Nicaragua demonstrates a real world application. The source code and MATLAB interface tools are freely available at http://mare2dem.ucsd.edu.

  13. Characterization of site conditions for selected seismic stations in eastern part of Romania

    NASA Astrophysics Data System (ADS)

    Grecu, B.; Zaharia, B.; Diaconescu, M.; Bala, A.; Nastase, E.; Constantinescu, E.; Tataru, D.

    2018-02-01

    Strong motion data are essential for seismic hazard assessment. To correctly understand and use this kind of data is necessary to have a good knowledge of local site conditions. Romania has one of the largest strong motion networks in Europe with 134 real-time stations. In this work, we aim to do a comprehensive site characterization for eight of these stations located in the eastern part of Romania. We make use of a various seismological dataset and we perform ambient noise and earthquake-based investigations to estimate the background noise level, the resonance frequencies and amplification of each site. We also derive the Vs30 parameter from the surface shear-wave velocity profiles obtained through the inversion of the Rayleigh waves recorded in active seismic measurements. Our analyses indicate similar results for seven stations: high noise levels for frequencies larger than 1 Hz, well defined fundamental resonance at low frequencies (0.15-0.29 Hz), moderate amplification levels (up to 4 units) for frequencies between 0.15 and 5-7 Hz and same soil class (type C) according to the estimated Vs30 and Eurocode 8. In contrast, the eighth station for which the soil class is evaluated of type B exhibits a very good noise level for a wide range of frequencies (0.01-20 Hz), a broader fundamental resonance at high frequencies ( 8 Hz) and a flat amplification curve between 0.1 and 3-4 Hz.

  14. A Real-Time Rejection Circuit to Automatically Reject Multiple Interfering Hopping Signals While Passing a Lower Level Desired Signal.

    DTIC Science & Technology

    contain the low level desired frequency components that are passed through an inverse transform device for producing a frequency domain signal of the desired signal uncorrupted by unwanted signals. Patent applications. (RRH)

  15. Osvaldo and Isis retrotransposons as markers of the Drosophila buzzatii colonisation in Australia.

    PubMed

    Guerreiro, María Pilar García; Fontdevila, Antonio

    2011-04-24

    Transposable elements (TEs) constitute an important source of genetic variability owing to their jumping and regulatory properties, and are considered to drive species evolution. Several factors that are able to induce TE transposition in genomes have been documented (for example environmental stress and inter- and intra-specific crosses) but in many instances the reasons for TE mobilisation have yet to be elucidated. Colonising populations constitute an ideal model for studying TE behaviour and distribution as they are exposed to different environmental and new demographic conditions. In this study, the distribution of two TEs, Osvaldo and Isis, was examined in two colonising populations of D. buzzatii from Australia. Comparing Osvaldo copy numbers between Australian and Old World (reported in previous studies) colonisations provides a valuable tool for elucidating the colonisation process and the effect of new conditions encountered by colonisers on TEs. The chromosomal distributions of Osvaldo and Isis retrotransposons in two colonising populations of D. buzzatii from Australia revealed sites of high insertion frequency (>10%) and low frequency sites. Comparisons between Osvaldo insertion profiles in colonising populations from the Old World and Australia demonstrate a tendency towards a higher number of highly occupied sites with higher insertion frequency in the Old World than in Australian populations. Tests concerning selection against deleterious TE insertions indicate that Isis is more controlled by purifying selection than Osvaldo. The distribution of both elements on chromosomal arms follows a Poisson distribution and there are non-significant positive correlations between highly occupied sites and chromosomal inversions. The occupancy profile of Osvaldo and Isis retrotransposons is characterised by the existence of high and low insertion frequency sites in the populations. These results demonstrate that Australian D. buzzatii populations were subjected to a founder effect during the colonisation process. Moreover, there are more sites with high insertion frequency in the Old World colonisation than in the Australian colonisation, indicating a probable stronger bottleneck effect in Australia. The results suggest that selection does not seem to play a major role, compared to demography, in the distribution of transposable elements in the Australian populations.

  16. Osvaldo and Isis retrotransposons as markers of the Drosophila buzzatii colonisation in Australia

    PubMed Central

    2011-01-01

    Background Transposable elements (TEs) constitute an important source of genetic variability owing to their jumping and regulatory properties, and are considered to drive species evolution. Several factors that are able to induce TE transposition in genomes have been documented (for example environmental stress and inter- and intra-specific crosses) but in many instances the reasons for TE mobilisation have yet to be elucidated. Colonising populations constitute an ideal model for studying TE behaviour and distribution as they are exposed to different environmental and new demographic conditions. In this study, the distribution of two TEs, Osvaldo and Isis, was examined in two colonising populations of D. buzzatii from Australia. Comparing Osvaldo copy numbers between Australian and Old World (reported in previous studies) colonisations provides a valuable tool for elucidating the colonisation process and the effect of new conditions encountered by colonisers on TEs. Results The chromosomal distributions of Osvaldo and Isis retrotransposons in two colonising populations of D. buzzatii from Australia revealed sites of high insertion frequency (>10%) and low frequency sites. Comparisons between Osvaldo insertion profiles in colonising populations from the Old World and Australia demonstrate a tendency towards a higher number of highly occupied sites with higher insertion frequency in the Old World than in Australian populations. Tests concerning selection against deleterious TE insertions indicate that Isis is more controlled by purifying selection than Osvaldo. The distribution of both elements on chromosomal arms follows a Poisson distribution and there are non-significant positive correlations between highly occupied sites and chromosomal inversions. Conclusions The occupancy profile of Osvaldo and Isis retrotransposons is characterised by the existence of high and low insertion frequency sites in the populations. These results demonstrate that Australian D. buzzatii populations were subjected to a founder effect during the colonisation process. Moreover, there are more sites with high insertion frequency in the Old World colonisation than in the Australian colonisation, indicating a probable stronger bottleneck effect in Australia. The results suggest that selection does not seem to play a major role, compared to demography, in the distribution of transposable elements in the Australian populations. PMID:21513573

  17. An Objective Rationale for the Choice of Regularisation Parameter with Application to Global Multiple-Frequency S-Wave Tomography

    NASA Astrophysics Data System (ADS)

    Zaroli, C.; Sambridge, M.; Leveque, J. J.; Debayle, E.; Nolet, G.

    2014-12-01

    In a linear ill-posed inverse problem, the regularisation parameter (damping) controls the balance between minimising both the residual data misfit and the model norm. Poor knowledge of data uncertainties often makes the selection of damping rather arbitrary. To go beyond that subjectivity, an objective rationale for the choice of damping is presented, which is based on the coherency of delay-time estimates in different frequency bands. Our method is tailored to the problem of global Multiple-Frequency Tomography, using a data set of 287078 S-wave delay-times measured in five frequency bands (10, 15, 22, 34, 51 s central periods). Whereas for each ray path the delay-time estimates should vary coherently from one period to the other, the noise most likely is not coherent. Thus, the lack of coherency of the information in different frequency bands is exploited, using an analogy with the cross-validation method, to identify models dominated by noise.In addition, a sharp change of behaviour of the model infinity-norm, as the damping becomes lower than a threshold value, is interpreted as the signature of data noise starting to significantly pollute at least one model component. Models with damping larger than this threshold are diagnosed as being constructed with poor data exploitation.Finally, a preferred model is selected from the remaining range of permitted model solutions. This choice is quasi-objective in terms of model interpretation, as the selected model shows a high degree of similarity with almost all other permitted models. The obtained tomographic model is displayed in mid lower-mantle (660-1910 km depth), and is shown to be mostly compatible with three other recent global shear-velocity models, while significant differences can be noticed. A wider application of the presented rationale should permit us to converge towards more objective seismic imaging of the Earth's mantle, using as much as possible of the relevant structural information in the data. This work was recently published: Zaroli, C., Sambridge, M., Lévêque, J.-J., Debayle, E., and Nolet, G. (2013) - Solid Earth, 4, 357-371, doi:10.5194/se-4-357-2013

  18. A general methodology for inverse estimation of the elastic and anelastic properties of anisotropic open-cell porous materials—with application to a melamine foam

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cuenca, Jacques, E-mail: jcuenca@kth.se; Van der Kelen, Christophe; Göransson, Peter

    2014-02-28

    This paper proposes an inverse estimation method for the characterisation of the elastic and anelastic properties of the frame of anisotropic open-cell foams used for sound absorption. A model of viscoelasticity based on a fractional differential constitutive equation is used, leading to an augmented Hooke's law in the frequency domain, where the elastic and anelastic phenomena appear as distinctive terms in the stiffness matrix. The parameters of the model are nine orthotropic elastic moduli, three angles of orientation of the material principal directions and three parameters governing the anelastic frequency dependence. The inverse estimation consists in numerically fitting the modelmore » on a set of transfer functions extracted from a sample of material. The setup uses a seismic-mass measurement repeated in the three directions of space and is placed in a vacuum chamber in order to remove the air from the pores of the sample. The method allows to reconstruct the full frequency-dependent complex stiffness matrix of the frame of an anisotropic open-cell foam and in particular it provides the frequency of maximum energy dissipation by viscoelastic effects. The characterisation of a melamine foam sample is performed and the relation between the fractional-derivative model and other types of parameterisations of the augmented Hooke's law is discussed.« less

  19. A general methodology for inverse estimation of the elastic and anelastic properties of anisotropic open-cell porous materials—with application to a melamine foam

    NASA Astrophysics Data System (ADS)

    Cuenca, Jacques; Van der Kelen, Christophe; Göransson, Peter

    2014-02-01

    This paper proposes an inverse estimation method for the characterisation of the elastic and anelastic properties of the frame of anisotropic open-cell foams used for sound absorption. A model of viscoelasticity based on a fractional differential constitutive equation is used, leading to an augmented Hooke's law in the frequency domain, where the elastic and anelastic phenomena appear as distinctive terms in the stiffness matrix. The parameters of the model are nine orthotropic elastic moduli, three angles of orientation of the material principal directions and three parameters governing the anelastic frequency dependence. The inverse estimation consists in numerically fitting the model on a set of transfer functions extracted from a sample of material. The setup uses a seismic-mass measurement repeated in the three directions of space and is placed in a vacuum chamber in order to remove the air from the pores of the sample. The method allows to reconstruct the full frequency-dependent complex stiffness matrix of the frame of an anisotropic open-cell foam and in particular it provides the frequency of maximum energy dissipation by viscoelastic effects. The characterisation of a melamine foam sample is performed and the relation between the fractional-derivative model and other types of parameterisations of the augmented Hooke's law is discussed.

  20. Different segregation patterns in five carriers due to a pericentric inversion of chromosome 1.

    PubMed

    Luo, Yuqin; Xu, Chenming; Sun, Yixi; Wang, Liya; Chen, Songchang; Jin, Fan

    2014-12-01

    Pericentric inversion can produce recombinant gametes; however, meiotic segregation studies on the relationship between the frequency of recombinants and the inverted segment size are rare. Triple-color fluorescence in situ hybridization (FISH) was performed to analyze the meiotic behavior in five inv(1) carriers with different breakpoints. Recombination gametes were absent in Patient 1, whereas the percentages of the recombinants in Patients 2, 3, 4, and 5 were of 9.2%, 15.3%, 17.3%, and 40.9%, respectively. A significant difference was present for the frequencies of the recombinant spermatozoa among the five patients (p < 0.001). For each patient, the frequency of the two types of recombinant gametes (dup(1p)/del(1q) or del(1p)/dup(1q)) did not exhibit a significant difference in comparison with the expected 1:1 ratio (p > 0.05). The meiotic segregation of nine inv(1) carriers (including those presented in this paper) is now available. A significant correlation was discovered between the rate of recombination and the proportion of the chromosome implicated in the inversion (R = 0.9435, p < 0.001). The frequency of the recombinant gametes was directly related to the proportion of the chromosome that was inverted. Sperm-FISH allowed an additional comprehension of the patterns of meiotic segregation and provided accurate genetic counseling.

  1. Estimation of pseudo-2D shear-velocity section by inversion of high frequency surface waves

    USGS Publications Warehouse

    Luo, Y.; Liu, J.; Xia, J.; Xu, Y.; Liu, Q.

    2006-01-01

    A scheme to generate pseudo-2D shear-velocity sections with high horizontal resolution and low field cost by inversion of high frequency surface waves is presented. It contains six steps. The key step is the joint method of crossed correlation and phase shift scanning. This joint method chooses only two traces to generate image of dispersion curve. For Rayleigh-wave dispersion is most important for estimation of near-surface shear-wave velocity, it can effectively obtain reliable images of dispersion curves with a couple of traces. The result of a synthetic example shows the feasibility of this scheme. ?? 2005 Society of Exploration Geophysicists.

  2. A BASIC program for the removal of noise from reaction traces using Fourier filtering.

    PubMed

    Brittain, T

    1989-04-01

    Software for the removal of noise from reaction curves using the principle of Fourier filtering has been written in BASIC to execute on a PC. The program inputs reaction traces which are subjected to a rotation-inversion process, to produce functions suitable for Fourier analysis. Fourier transformation into the frequency domain is followed by multiplication of the transform by a rectangular filter function, to remove the noise frequencies. Inverse transformation then yields a noise-reduced reaction trace suitable for further analysis. The program is interactive at each stage and could easily be modified to remove noise from a range of input data types.

  3. Recent Airborne EM surveying and processing - Studies from the North Sea coast

    NASA Astrophysics Data System (ADS)

    Meyer, U.; Siemon, B.; Steuer, A.; Wiederhold, H.

    2012-12-01

    The last decade has shown numerous improvements in AEM instrumentation as well as in AEM data processing and evaluation. The latter is essential for successfully using AEM data to derive reliable spatial conductivity distributions for, e.g. geological and hydrogeological 3D modeling. Besides sound data acquisition in order to measure AEM data having a sufficiently high S/N ratio, calibration, leveling and handling of man-made effects are essential to get data sets which are ready for enhanced inversion and interpretation. The Federal Institute for Geosciences and Natural resources (BGR) has been using frequency-domain helicopter-borne electromagnetic systems for more than three decades. The current system is a six-frequency FAS-RESOLVE system operating at 0.4 to 133 kHz. Particularly the high-frequency data require specific evaluation as the widely used quasi-static approximation is not sufficiently accurate for both forward and inverse modeling. The inversion results can be further improved by using internal (from AEM sites to AEM sites) or external (from boreholes or ground geophysical sites to AEM sites) constraints or by jointly inverting AEM and other geophysical data. Finally, examples from recent AEM surveys at the North Sea coast will be presented.

  4. Parana Basin Structure from Multi-Objective Inversion of Surface Wave and Receiver Function by Competent Genetic Algorithm

    NASA Astrophysics Data System (ADS)

    An, M.; Assumpcao, M.

    2003-12-01

    The joint inversion of receiver function and surface wave is an effective way to diminish the influences of the strong tradeoff among parameters and the different sensitivity to the model parameters in their respective inversions, but the inversion problem becomes more complex. Multi-objective problems can be much more complicated than single-objective inversion in the model selection and optimization. If objectives are involved and conflicting, models can be ordered only partially. In this case, Pareto-optimal preference should be used to select solutions. On the other hand, the inversion to get only a few optimal solutions can not deal properly with the strong tradeoff between parameters, the uncertainties in the observation, the geophysical complexities and even the incompetency of the inversion technique. The effective way is to retrieve the geophysical information statistically from many acceptable solutions, which requires more competent global algorithms. Competent genetic algorithms recently proposed are far superior to the conventional genetic algorithm and can solve hard problems quickly, reliably and accurately. In this work we used one of competent genetic algorithms, Bayesian Optimization Algorithm as the main inverse procedure. This algorithm uses Bayesian networks to draw out inherited information and can use Pareto-optimal preference in the inversion. With this algorithm, the lithospheric structure of Paran"› basin is inverted to fit both the observations of inter-station surface wave dispersion and receiver function.

  5. Sperm-FISH analysis in a pericentric chromosome 1 inversion, 46,XY,inv(1)(p22q42), associated with infertility.

    PubMed

    Chantot-Bastaraud, S; Ravel, C; Berthaut, I; McElreavey, K; Bouchard, P; Mandelbaum, J; Siffroi, J P

    2007-01-01

    No phenotypic effect is observed in most inversion heterozygotes. However, reproductive risks may occur in the form of infertility, spontaneous abortions or chromosomally unbalanced children as a consequence of meiotic recombination between inverted and non-inverted chromosomes. An odd number of crossovers within the inverted segment results in gametes bearing recombinant chromosomes with a duplication of the region outside of the inversion segment of one arm and a deletion of the terminal segment of the other arm [dup(p)/del(q) and del(p)/dup(q)]. Using fluorescence in-situ hybridization (FISH), the chromosome segregation of a pericentric inversion of chromosome 1 was studied in spermatozoa of a inv(1)(p22q42) heterozygous carrier. Three-colour FISH was performed on sperm samples using a probe mixture consisting of chromosome 1p telomere-specific probe, chromosome 1q telomere-specific probe and chromosome 18 centromere-specific alpha satellite DNA probe. The frequency of the non-recombinant product was 80.1%. The frequencies of the two types of recombinants carrying a duplication of the short arm and a deletion of the long arm, and vice versa, were respectively 7.6 and 7.2%, and these frequencies were not statistically significant from the expected ratio of 1:1. Sperm-FISH allows the further understanding of segregation patterns and their effect on reproductive failure and allows an accurate genetic counselling.

  6. The effect of environmental uncertainty on morphological design and fluid balance in Sarracenia purpurea L.

    PubMed

    Kingsolver, Joel

    1981-03-01

    To explore principles of organismic design in fluctuating environments, morphological design of the leaf of the pitcher-plant, Sarracenia purpurea, was studied for a population in northern Michigan. The design criterion focused upon the leaf shape and minimum size which effectively avoids leaf desiccation (complete loss of fluid from the leaf cavity) in the face of fluctuating rainfall and meteorological conditions. Bowl- and pitcher-shaped leaves were considered. Simulations show that the pitcher geometry experiences less frequent desiccation than bowls of the same size. Desiccation frequency is inversely related to leaf size; the size distribution of pitcher leaves in the field shows that the majority of pitchers desiccate only 1-3 times per season on average, while smaller pitchers may average up to 8 times per season. A linear filter model of an organism in a fluctuating environment is presented, in which the organism selectively filters the temporal patterns of environmental input. General measures of rainfall predictability based upon information theory and spectral analysis are consistent with the model of a pitcher leaf as a low-pass (frequency) filter which avoids desiccation by eliminating high-frequency rainfall variability.

  7. Reversion of 6-thioguanine resistant Chinese hamster cell lines: agent specificity and evidence for the repair of promutagenic lesions.

    PubMed

    Hodgkiss, R J; Brennand, J; Fox, M

    1980-02-01

    The kinetics and mutagen specificity of reversion of an HGPRT(-)TG(R) line of Chinese hamster cells have been examined in detail by measuring the frequency of HAT(R) colonies. Alkylating agents which produce relatively high levels of O-atom reaction were effective in inducing reversion. MMS, DMS and u.v. were less efficient, and aflatoxin B1, acridine orange and N-acetoxy-AAF were completely ineffective. For agents which were effective, the relationship between HAT(R) colony frequency and dose of mutagen was linear at early expression times (6 h). HAT(R) colony frequency fell subsequently at all doses and the rate and extent of the fall was inversely related to dose. These observations suggest repair of a pro-mutagenic DNA lesion. Other TG(R) mutants isolated from the same wild-type cell line under different selective conditions were also tested for revertibility after exposure to the same mutagens. The majority did not revert, this suggests that they carry deletions within the structural gene for HGPRT. The infrequent revertible lines all arose spontaneously and our evidence suggests that they carry nonsense mutations.

  8. Text mining for search term development in systematic reviewing: A discussion of some methods and challenges.

    PubMed

    Stansfield, Claire; O'Mara-Eves, Alison; Thomas, James

    2017-09-01

    Using text mining to aid the development of database search strings for topics described by diverse terminology has potential benefits for systematic reviews; however, methods and tools for accomplishing this are poorly covered in the research methods literature. We briefly review the literature on applications of text mining for search term development for systematic reviewing. We found that the tools can be used in 5 overarching ways: improving the precision of searches; identifying search terms to improve search sensitivity; aiding the translation of search strategies across databases; searching and screening within an integrated system; and developing objectively derived search strategies. Using a case study and selected examples, we then reflect on the utility of certain technologies (term frequency-inverse document frequency and Termine, term frequency, and clustering) in improving the precision and sensitivity of searches. Challenges in using these tools are discussed. The utility of these tools is influenced by the different capabilities of the tools, the way the tools are used, and the text that is analysed. Increased awareness of how the tools perform facilitates the further development of methods for their use in systematic reviews. Copyright © 2017 John Wiley & Sons, Ltd.

  9. The effects of pre-processing strategies in sentiment analysis of online movie reviews

    NASA Astrophysics Data System (ADS)

    Zin, Harnani Mat; Mustapha, Norwati; Murad, Masrah Azrifah Azmi; Sharef, Nurfadhlina Mohd

    2017-10-01

    With the ever increasing of internet applications and social networking sites, people nowadays can easily express their feelings towards any products and services. These online reviews act as an important source for further analysis and improved decision making. These reviews are mostly unstructured by nature and thus, need processing like sentiment analysis and classification to provide a meaningful information for future uses. In text analysis tasks, the appropriate selection of words/features will have a huge impact on the effectiveness of the classifier. Thus, this paper explores the effect of the pre-processing strategies in the sentiment analysis of online movie reviews. In this paper, supervised machine learning method was used to classify the reviews. The support vector machine (SVM) with linear and non-linear kernel has been considered as classifier for the classification of the reviews. The performance of the classifier is critically examined based on the results of precision, recall, f-measure, and accuracy. Two different features representations were used which are term frequency and term frequency-inverse document frequency. Results show that the pre-processing strategies give a significant impact on the classification process.

  10. Time-domain full waveform inversion using instantaneous phase information with damping

    NASA Astrophysics Data System (ADS)

    Luo, Jingrui; Wu, Ru-Shan; Gao, Fuchun

    2018-06-01

    In time domain, the instantaneous phase can be obtained from the complex seismic trace using Hilbert transform. The instantaneous phase information has great potential in overcoming the local minima problem and improving the result of full waveform inversion. However, the phase wrapping problem, which comes from numerical calculation, prevents its application. In order to avoid the phase wrapping problem, we choose to use the exponential phase combined with the damping method, which gives instantaneous phase-based multi-stage inversion. We construct the objective functions based on the exponential instantaneous phase, and also derive the corresponding gradient operators. Conventional full waveform inversion and the instantaneous phase-based inversion are compared with numerical examples, which indicates that in the case without low frequency information in seismic data, our method is an effective and efficient approach for initial model construction for full waveform inversion.

  11. Estimation of Atmospheric Methane Surface Fluxes Using a Global 3-D Chemical Transport Model

    NASA Astrophysics Data System (ADS)

    Chen, Y.; Prinn, R.

    2003-12-01

    Accurate determination of atmospheric methane surface fluxes is an important and challenging problem in global biogeochemical cycles. We use inverse modeling to estimate annual, seasonal, and interannual CH4 fluxes between 1996 and 2001. The fluxes include 7 time-varying seasonal (3 wetland, rice, and 3 biomass burning) and 3 steady aseasonal (animals/waste, coal, and gas) global processes. To simulate atmospheric methane, we use the 3-D chemical transport model MATCH driven by NCEP reanalyzed observed winds at a resolution of T42 ( ˜2.8° x 2.8° ) in the horizontal and 28 levels (1000 - 3 mb) in the vertical. By combining existing datasets of individual processes, we construct a reference emissions field that represents our prior guess of the total CH4 surface flux. For the methane sink, we use a prescribed, annually-repeating OH field scaled to fit methyl chloroform observations. MATCH is used to produce both the reference run from the reference emissions, and the time-dependent sensitivities that relate individual emission processes to observations. The observational data include CH4 time-series from ˜15 high-frequency (in-situ) and ˜50 low-frequency (flask) observing sites. Most of the high-frequency data, at a time resolution of 40-60 minutes, have not previously been used in global scale inversions. In the inversion, the high-frequency data generally have greater weight than the weekly flask data because they better define the observational monthly means. The Kalman Filter is used as the optimal inversion technique to solve for emissions between 1996-2001. At each step in the inversion, new monthly observations are utilized and new emissions estimates are produced. The optimized emissions represent deviations from the reference emissions that lead to a better fit to the observations. The seasonal processes are optimized for each month, and contain the methane seasonality and interannual variability. The aseasonal processes, which are less variable, are solved as constant emissions over the entire time period. The Kalman Filter also produces emission uncertainties which quantify the ability of the observing network to constrain different processes. The sensitivity of the inversion to different observing sites and model sampling strategies is also tested. In general, the inversion reduces coal and gas emissions, and increases rice and biomass burning emissions relative to the reference case. Increases in both tropical and northern wetland emissions are found to have dominated the strong atmospheric methane increase in 1998. Northern wetlands are the best constrained processes, while tropical regions are poorly constrained and will require additional observations in the future for significant uncertainty reduction. The results of this study also suggest that interannual varying transport like NCEP and high-frequency measurements should be used when solving for methane emissions at monthly time resolution. Better estimates of global OH fluctuations are also necessary to fully describe the interannual behavior of methane observations.

  12. Probing the solar core with low-degree p modes

    NASA Astrophysics Data System (ADS)

    Roxburgh, I. W.; Vorontsov, S. V.

    2002-01-01

    We address the question of what could be learned about the solar core structure if the seismic data were limited to low-degree modes only. The results of three different experiments are described. The first is the linearized structural inversion of the p-mode frequencies of a solar model modified slightly in the energy-generating core, using the original (unmodified) model as an initial guess. In the second experiment, we invert the solar p-mode frequencies measured in the 32-month subset of BiSON data (Chaplin et al. 1998), degraded with additional 0.1 μHz random errors, using a model of 2.6 Gyr age from the solar evolutionary sequence as an initial approximation. This second inversion is non-linear. In the third experiment, we compare the same set of BiSON frequencies with current reference solar model.

  13. GuiTope: an application for mapping random-sequence peptides to protein sequences.

    PubMed

    Halperin, Rebecca F; Stafford, Phillip; Emery, Jack S; Navalkar, Krupa Arun; Johnston, Stephen Albert

    2012-01-03

    Random-sequence peptide libraries are a commonly used tool to identify novel ligands for binding antibodies, other proteins, and small molecules. It is often of interest to compare the selected peptide sequences to the natural protein binding partners to infer the exact binding site or the importance of particular residues. The ability to search a set of sequences for similarity to a set of peptides may sometimes enable the prediction of an antibody epitope or a novel binding partner. We have developed a software application designed specifically for this task. GuiTope provides a graphical user interface for aligning peptide sequences to protein sequences. All alignment parameters are accessible to the user including the ability to specify the amino acid frequency in the peptide library; these frequencies often differ significantly from those assumed by popular alignment programs. It also includes a novel feature to align di-peptide inversions, which we have found improves the accuracy of antibody epitope prediction from peptide microarray data and shows utility in analyzing phage display datasets. Finally, GuiTope can randomly select peptides from a given library to estimate a null distribution of scores and calculate statistical significance. GuiTope provides a convenient method for comparing selected peptide sequences to protein sequences, including flexible alignment parameters, novel alignment features, ability to search a database, and statistical significance of results. The software is available as an executable (for PC) at http://www.immunosignature.com/software and ongoing updates and source code will be available at sourceforge.net.

  14. Global high-frequency source imaging accounting for complexity in Green's functions

    NASA Astrophysics Data System (ADS)

    Lambert, V.; Zhan, Z.

    2017-12-01

    The general characterization of earthquake source processes at long periods has seen great success via seismic finite fault inversion/modeling. Complementary techniques, such as seismic back-projection, extend the capabilities of source imaging to higher frequencies and reveal finer details of the rupture process. However, such high frequency methods are limited by the implicit assumption of simple Green's functions, which restricts the use of global arrays and introduces artifacts (e.g., sweeping effects, depth/water phases) that require careful attention. This motivates the implementation of an imaging technique that considers the potential complexity of Green's functions at high frequencies. We propose an alternative inversion approach based on the modest assumption that the path effects contributing to signals within high-coherency subarrays share a similar form. Under this assumption, we develop a method that can combine multiple high-coherency subarrays to invert for a sparse set of subevents. By accounting for potential variability in the Green's functions among subarrays, our method allows for the utilization of heterogeneous global networks for robust high resolution imaging of the complex rupture process. The approach also provides a consistent framework for examining frequency-dependent radiation across a broad frequency spectrum.

  15. The Effect of Common Inversion Polymorphisms In(2L)t and In(3R)Mo on Patterns of Transcriptional Variation in Drosophila melanogaster.

    PubMed

    Lavington, Erik; Kern, Andrew D

    2017-11-06

    Chromosomal inversions are a ubiquitous feature of genetic variation. Theoretical models describe several mechanisms by which inversions can drive adaptation and be maintained as polymorphisms. While inversions have been shown previously to be under selection, or contain genetic variation under selection, the specific phenotypic consequences of inversions leading to their maintenance remain unclear. Here we use genomic sequence and expression data from the Drosophila Genetic Reference Panel (DGRP) to explore the effects of two cosmopolitan inversions, In ( 2L ) t and In ( 3R ) Mo , on patterns of transcriptional variation. We demonstrate that each inversion has a significant effect on transcript abundance for hundreds of genes across the genome. Inversion-affected loci (IAL) appear both within inversions as well as on unlinked chromosomes. Importantly, IAL do not appear to be influenced by the previously reported genome-wide expression correlation structure. We found that five genes involved with sterol uptake, four of which are Niemann-Pick Type 2 orthologs, are upregulated in flies with In ( 3R ) Mo but do not have SNPs in linkage disequilibrium (LD) with the inversion. We speculate that this upregulation is driven by genetic variation in mod ( mdg4 ) that is in LD with In ( 3R ) Mo We find that there is little evidence for a regional or position effect of inversions on gene expression at the chromosomal level, but do find evidence for the distal breakpoint of In ( 3R ) Mo interrupting one gene and possibly disassociating the two flanking genes from regulatory elements. Copyright © 2017 Lavington and Kern.

  16. The Effect of Common Inversion Polymorphisms In(2L)t and In(3R)Mo on Patterns of Transcriptional Variation in Drosophila melanogaster

    PubMed Central

    Lavington, Erik; Kern, Andrew D.

    2017-01-01

    Chromosomal inversions are a ubiquitous feature of genetic variation. Theoretical models describe several mechanisms by which inversions can drive adaptation and be maintained as polymorphisms. While inversions have been shown previously to be under selection, or contain genetic variation under selection, the specific phenotypic consequences of inversions leading to their maintenance remain unclear. Here we use genomic sequence and expression data from the Drosophila Genetic Reference Panel (DGRP) to explore the effects of two cosmopolitan inversions, In(2L)t and In(3R)Mo, on patterns of transcriptional variation. We demonstrate that each inversion has a significant effect on transcript abundance for hundreds of genes across the genome. Inversion-affected loci (IAL) appear both within inversions as well as on unlinked chromosomes. Importantly, IAL do not appear to be influenced by the previously reported genome-wide expression correlation structure. We found that five genes involved with sterol uptake, four of which are Niemann-Pick Type 2 orthologs, are upregulated in flies with In(3R)Mo but do not have SNPs in linkage disequilibrium (LD) with the inversion. We speculate that this upregulation is driven by genetic variation in mod(mdg4) that is in LD with In(3R)Mo. We find that there is little evidence for a regional or position effect of inversions on gene expression at the chromosomal level, but do find evidence for the distal breakpoint of In(3R)Mo interrupting one gene and possibly disassociating the two flanking genes from regulatory elements. PMID:28916647

  17. Multi-parameter Full-waveform Inversion for Acoustic VTI Medium with Surface Seismic Data

    NASA Astrophysics Data System (ADS)

    Cheng, X.; Jiao, K.; Sun, D.; Huang, W.; Vigh, D.

    2013-12-01

    Full-waveform Inversion (FWI) attracts wide attention recently in oil and gas industry as a new promising tool for high resolution subsurface velocity model building. While the traditional common image point gather based tomography method aims to focus post-migrated data in depth domain, FWI aims to directly fit the observed seismic waveform in either time or frequency domain. The inversion is performed iteratively by updating the velocity fields to reduce the difference between the observed and the simulated data. It has been shown the inversion is very sensitive to the starting velocity fields, and data with long offsets and low frequencies is crucial for the success of FWI to overcome this sensitivity. Considering the importance of data with long offsets and low frequencies, in most geologic environment, anisotropy is an unavoidable topic for FWI especially at long offsets, since anisotropy tends to have more pronounced effects on waves traveled for a great distance. In VTI medium, this means more horizontal velocity will be registered in middle-to-long offset data, while more vertical velocity will be registered in near-to-middle offset data. Up to date, most of real world applications of FWI still remain in isotropic medium, and only a few studies have been shown to account for anisotropy. And most of those studies only account for anisotropy in waveform simulation, but not invert for those anisotropy fields. Multi-parameter inversion for anisotropy fields, even in VTI medium, remains as a hot topic in the field. In this study, we develop a strategy for multi-parameter FWI for acoustic VTI medium with surface seismic data. Because surface seismic data is insensitivity to the delta fields, we decide to hold the delta fields unchanged during our inversion, and invert only for vertical velocity and epsilon fields. Through parameterization analysis and synthetic tests, we find that it is more feasible to invert for the parameterization as vertical and horizontal velocities instead of inverting for the parameterization as vertical velocity and epsilon fields. We develop a hierarchical approach to invert for vertical velocity first but hold epsilon unchanged and only switch to simultaneous inversion when vertical velocity inversion are approaching convergence. During simultaneous inversion, we observe significant acceleration in the convergence when incorporates second order information and preconditioning into inversion. We demonstrate the success of our strategy for VTI FWI using synthetic and real data examples from the Gulf of Mexico. Our results show that incorporation of VTI FWI improves migration of large offset acquisition data, and produces better focused migration images to be used in exploration, production and development of oil fields.

  18. Stable source reconstruction from a finite number of measurements in the multi-frequency inverse source problem

    NASA Astrophysics Data System (ADS)

    Karamehmedović, Mirza; Kirkeby, Adrian; Knudsen, Kim

    2018-06-01

    We consider the multi-frequency inverse source problem for the scalar Helmholtz equation in the plane. The goal is to reconstruct the source term in the equation from measurements of the solution on a surface outside the support of the source. We study the problem in a certain finite dimensional setting: from measurements made at a finite set of frequencies we uniquely determine and reconstruct sources in a subspace spanned by finitely many Fourier–Bessel functions. Further, we obtain a constructive criterion for identifying a minimal set of measurement frequencies sufficient for reconstruction, and under an additional, mild assumption, the reconstruction method is shown to be stable. Our analysis is based on a singular value decomposition of the source-to-measurement forward operators and the distribution of positive zeros of the Bessel functions of the first kind. The reconstruction method is implemented numerically and our theoretical findings are supported by numerical experiments.

  19. Apparatus for direct-to-digital spatially-heterodyned holography

    DOEpatents

    Thomas, Clarence E.; Hanson, Gregory R.

    2006-12-12

    An apparatus operable to record a spatially low-frequency heterodyne hologram including spatially heterodyne fringes for Fourier analysis includes: a laser; a beamsplitter optically coupled to the laser; an object optically coupled to the beamsplitter; a focusing lens optically coupled to both the beamsplitter and the object; a digital recorder optically coupled to the focusing lens; and a computer that performs a Fourier transform, applies a digital filter, and performs an inverse Fourier transform. A reference beam and an object beam are focused by the focusing lens at a focal plane of the digital recorder to form a spatially low-frequency heterodyne hologram including spatially heterodyne fringes for Fourier analysis which is recorded by the digital recorder, and the computer transforms the recorded spatially low-frequency heterodyne hologram including spatially heterodyne fringes and shifts axes in Fourier space to sit on top of a heterodyne carrier frequency defined by an angle between the reference beam and the object beam and cuts off signals around an original origin before performing the inverse Fourier transform.

  20. Period of vibration of axially vibrating truly nonlinear rod

    NASA Astrophysics Data System (ADS)

    Cveticanin, L.

    2016-07-01

    In this paper the axial vibration of a muscle whose fibers are parallel to the direction of muscle compression is investigated. The model is a clamped-free rod with a strongly nonlinear elastic property. Axial vibration is described by a nonlinear partial differential equation. A solution of the equation is constructed for special initial conditions by using the method of separation of variables. The partial differential equation is separated into two uncoupled strongly nonlinear second order differential equations. Both equations, with displacement function and with time function are exactly determined. Exact solutions are given in the form of inverse incomplete and inverse complete Beta function. Using boundary and initial conditions, the frequency of vibration is obtained. It has to be mentioned that the determined frequency represents the exact analytic description for the axially vibrating truly nonlinear clamped-free rod. The procedure suggested in this paper is applied for calculation of the frequency of the longissimus dorsi muscle of a cow. The influence of elasticity order and elasticity coefficient on the frequency property is tested.

  1. Meiotic segregation analysis in spermatozoa of pericentric inversion carriers using fluorescence in-situ hybridization.

    PubMed

    Morel, F; Laudier, B; Guérif, F; Couet, M L; Royère, D; Roux, C; Bresson, J L; Amice, V; De Braekeleer, M; Douet-Guilbert, N

    2007-01-01

    Pericentric inversions are structural chromosomal abnormalities resulting from two breaks, one on either side of the centromere, within the same chromosome, followed by 180 degrees rotation and reunion of the inverted segment. They can perturb spermatogenesis and lead to the production of unbalanced gametes through the formation of an inversion loop. We report here the analysis of the meiotic segregation in spermatozoa from six pericentric inversion carriers by multicolour fluorescence in-situ hybridization (FISH) and review the literature. The frequencies of the non-recombinant products (inversion or normal chromosomes) were 80% for the inv(20), 91.41% for the inv(12), 99.43% for the inv(2), 68.12% for the inv(1), 97% for the inv(8)(p12q21) and 60.94% for the inv(8)(p12q24.1). The meiotic segregation of 20 pericentric inversions (including ours) is now available. The frequency of unbalanced spermatozoa varies from 0 to 37.85%. The probability of a crossover within the inverted segment is affected by the chromosome and region involved, the length of the inverted segment and the location of the breakpoints. No recombinant chromosomes were produced when the inverted segment involved <30% of the chromosome length (independent of the size of the inverted segment). Between 30 and 50%, few recombinant chromosomes were produced, inducing a slightly increased risk of aneusomy of recombination in the offspring. The risk of aneusomy became very important when the inverted segment was >50% of the chromosome length. Studies on spermatozoa from inversion carriers help in the comprehension of the mechanisms of meiotic segregation. They should be integrated in the genetic exploration of the infertile men to give them a personalized risk assessment of unbalanced spermatozoa.

  2. Research and application of spectral inversion technique in frequency domain to improve resolution of converted PS-wave

    NASA Astrophysics Data System (ADS)

    Zhang, Hua; He, Zhen-Hua; Li, Ya-Lin; Li, Rui; He, Guamg-Ming; Li, Zhong

    2017-06-01

    Multi-wave exploration is an effective means for improving precision in the exploration and development of complex oil and gas reservoirs that are dense and have low permeability. However, converted wave data is characterized by a low signal-to-noise ratio and low resolution, because the conventional deconvolution technology is easily affected by the frequency range limits, and there is limited scope for improving its resolution. The spectral inversion techniques is used to identify λ/8 thin layers and its breakthrough regarding band range limits has greatly improved the seismic resolution. The difficulty associated with this technology is how to use the stable inversion algorithm to obtain a high-precision reflection coefficient, and then to use this reflection coefficient to reconstruct broadband data for processing. In this paper, we focus on how to improve the vertical resolution of the converted PS-wave for multi-wave data processing. Based on previous research, we propose a least squares inversion algorithm with a total variation constraint, in which we uses the total variance as a priori information to solve under-determined problems, thereby improving the accuracy and stability of the inversion. Here, we simulate the Gaussian fitting amplitude spectrum to obtain broadband wavelet data, which we then process to obtain a higher resolution converted wave. We successfully apply the proposed inversion technology in the processing of high-resolution data from the Penglai region to obtain higher resolution converted wave data, which we then verify in a theoretical test. Improving the resolution of converted PS-wave data will provide more accurate data for subsequent velocity inversion and the extraction of reservoir reflection information.

  3. Jump-and-return sandwiches: A new family of binomial-like selective inversion sequences with improved performance

    NASA Astrophysics Data System (ADS)

    Brenner, Tom; Chen, Johnny; Stait-Gardner, Tim; Zheng, Gang; Matsukawa, Shingo; Price, William S.

    2018-03-01

    A new family of binomial-like inversion sequences, named jump-and-return sandwiches (JRS), has been developed by inserting a binomial-like sequence into a standard jump-and-return sequence, discovered through use of a stochastic Genetic Algorithm optimisation. Compared to currently used binomial-like inversion sequences (e.g., 3-9-19 and W5), the new sequences afford wider inversion bands and narrower non-inversion bands with an equal number of pulses. As an example, two jump-and-return sandwich 10-pulse sequences achieved 95% inversion at offsets corresponding to 9.4% and 10.3% of the non-inversion band spacing, compared to 14.7% for the binomial-like W5 inversion sequence, i.e., they afforded non-inversion bands about two thirds the width of the W5 non-inversion band.

  4. Spontaneous mirror-symmetry breaking induces inverse energy cascade in 3D active fluids

    PubMed Central

    Słomka, Jonasz; Dunkel, Jörn

    2017-01-01

    Classical turbulence theory assumes that energy transport in a 3D turbulent flow proceeds through a Richardson cascade whereby larger vortices successively decay into smaller ones. By contrast, an additional inverse cascade characterized by vortex growth exists in 2D fluids and gases, with profound implications for meteorological flows and fluid mixing. The possibility of a helicity-driven inverse cascade in 3D fluids had been rejected in the 1970s based on equilibrium-thermodynamic arguments. Recently, however, it was proposed that certain symmetry-breaking processes could potentially trigger a 3D inverse cascade, but no physical system exhibiting this phenomenon has been identified to date. Here, we present analytical and numerical evidence for the existence of an inverse energy cascade in an experimentally validated 3D active fluid model, describing microbial suspension flows that spontaneously break mirror symmetry. We show analytically that self-organized scale selection, a generic feature of many biological and engineered nonequilibrium fluids, can generate parity-violating Beltrami flows. Our simulations further demonstrate how active scale selection controls mirror-symmetry breaking and the emergence of a 3D inverse cascade. PMID:28193853

  5. Impaired pulsation absorber mechanism in idiopathic normal pressure hydrocephalus: laboratory investigation.

    PubMed

    Park, Eun-Hyoung; Eide, Per Kristian; Zurakowski, David; Madsen, Joseph R

    2012-12-01

    The pathophysiology of normal pressure hydrocephalus (NPH), and the related problem of patient selection for treatment of this condition, have been of great interest since the description of this seemingly paradoxical condition nearly 50 years ago. Recently, Eide has reported that measurements of the amplitude of the intracranial pressure (ICP) can both positively and negatively predict response to CSF shunting. Specifically, the fraction of time spent in a "high amplitude" (> 4 mm Hg) state predicted response to shunting, which may represent a marker for hydrocephalic pathophysiology. Increased ICP amplitude might suggest decreased brain compliance, meaning a static measure of a pressure-volume ratio. Recent studies of canine data have shown that the brain compliance can be described as a frequency-dependent function. The normal canine brain seems to show enhanced ability to absorb the pulsations around the heart rate, quantified as a cardiac pulsation absorbance (CPA), with properties like a notch filter in engineering. This frequency dependence of the function is diminished with development of hydrocephalus in dogs. In this pilot study, the authors sought to determine whether frequency dependence could be observed in humans, and whether the frequency dependence would be any different in epochs with high ICP amplitude compared with epochs of low ICP amplitude. Systems analysis was applied to arterial blood pressure (ABP) and ICP waveforms recorded from 10 patients undergoing evaluations of idiopathic NPH to calculate a time-varying transfer function that reveals frequency dependence and CPA, the measure of frequency-dependent compliance previously used in animal experiments. The ICP amplitude was also calculated in the same samples, so that epochs with high (> 4 mm Hg) versus low (≤ 4 mm Hg) amplitude could be compared in CPA and transfer functions. Transfer function analysis for the more "normal" epochs with low amplitude exhibits a dip or notch in the physiological frequency range of the heart rate, confirming in humans the pulsation absorber phenomenon previously observed in canine studies. Under high amplitude, however, the dip in the transfer function is absent. An inverse relationship between CPA index and ICP amplitude is evident and statistically significant. Thus, elevated ICP amplitude indicates decreased performance of the human pulsation absorber. The results suggest that the human intracranial system shows frequency dependence as seen in animal experiments. There is an inverse relationship between CPA index and ICP amplitude, indicating that higher amplitudes may occur with a reduced performance of the pulsation absorber. Our findings show that frequency dependence can be observed in humans and imply that reduced frequency-dependent compliance may be responsible for elevated ICP amplitude observed in patients who respond to CSF shunting.

  6. Bistability in dual-frequency nematic liquid crystals

    NASA Astrophysics Data System (ADS)

    Palto, S. P.; Barnik, M. I.

    2007-03-01

    Different modes of bistable switching in liquid crystals with frequency inversion of the dielectric anisotropy sign are discussed. The study is performed by numerical simulation and experimentally. It is shown that dual frequency driving can be effectively used to control switching between topologically equivalent and non-equivalent director field distributions. The experimental results on temperature performance of the dual-frequency switching and possible driving methods for energy consumption and expanding the temperature range are presented.

  7. Parsimony and goodness-of-fit in multi-dimensional NMR inversion

    NASA Astrophysics Data System (ADS)

    Babak, Petro; Kryuchkov, Sergey; Kantzas, Apostolos

    2017-01-01

    Multi-dimensional nuclear magnetic resonance (NMR) experiments are often used for study of molecular structure and dynamics of matter in core analysis and reservoir evaluation. Industrial applications of multi-dimensional NMR involve a high-dimensional measurement dataset with complicated correlation structure and require rapid and stable inversion algorithms from the time domain to the relaxation rate and/or diffusion domains. In practice, applying existing inverse algorithms with a large number of parameter values leads to an infinite number of solutions with a reasonable fit to the NMR data. The interpretation of such variability of multiple solutions and selection of the most appropriate solution could be a very complex problem. In most cases the characteristics of materials have sparse signatures, and investigators would like to distinguish the most significant relaxation and diffusion values of the materials. To produce an easy to interpret and unique NMR distribution with the finite number of the principal parameter values, we introduce a new method for NMR inversion. The method is constructed based on the trade-off between the conventional goodness-of-fit approach to multivariate data and the principle of parsimony guaranteeing inversion with the least number of parameter values. We suggest performing the inversion of NMR data using the forward stepwise regression selection algorithm. To account for the trade-off between goodness-of-fit and parsimony, the objective function is selected based on Akaike Information Criterion (AIC). The performance of the developed multi-dimensional NMR inversion method and its comparison with conventional methods are illustrated using real data for samples with bitumen, water and clay.

  8. A theory of the inverse magnetoelectric effect in layered magnetostrictive-piezoelectric structures

    NASA Astrophysics Data System (ADS)

    Filippov, D. A.; Radchenko, G. S.; Firsova, T. O.; Galkina, T. A.

    2017-05-01

    A theory of the inverse magnetoelectric effect in layered structures has been presented. The theory is based on solving the equations of elastodynamics and electrostatics separately for the magnetostrictive and piezoelectric phases, taking into account the conditions at the interface between the phases. Expressions for the coefficient of inverse magnetoelectric conversion through the parameters characterizing the magnetostrictive and piezoelectric phases have been obtained. Theoretical dependences of the inverse magnetoelectric conversion coefficient on the frequency of the alternating-current electric field for the three-layer PZT-Ni-PZT structure and the two-layer terfenol- D-PZT structure have been calculated. The results of the calculations are in good agreement with the experimental data.

  9. Rayleigh wave nonlinear inversion based on the Firefly algorithm

    NASA Astrophysics Data System (ADS)

    Zhou, Teng-Fei; Peng, Geng-Xin; Hu, Tian-Yue; Duan, Wen-Sheng; Yao, Feng-Chang; Liu, Yi-Mou

    2014-06-01

    Rayleigh waves have high amplitude, low frequency, and low velocity, which are treated as strong noise to be attenuated in reflected seismic surveys. This study addresses how to identify useful shear wave velocity profile and stratigraphic information from Rayleigh waves. We choose the Firefly algorithm for inversion of surface waves. The Firefly algorithm, a new type of particle swarm optimization, has the advantages of being robust, highly effective, and allows global searching. This algorithm is feasible and has advantages for use in Rayleigh wave inversion with both synthetic models and field data. The results show that the Firefly algorithm, which is a robust and practical method, can achieve nonlinear inversion of surface waves with high resolution.

  10. Large-scale high density 3D AMT for mineral exploration — A case history from volcanic massive sulfide Pb-Zn deposit with 2000 AMT sites

    NASA Astrophysics Data System (ADS)

    Chen, R.; Chen, S.; He, L.; Yao, H.; Li, H.; Xi, X.; Zhao, X.

    2017-12-01

    EM method plays a key role in volcanic massive sulfide (VMS) deposit which is with high grade and high economic value. However, the performance of high density 3D AMT in detecting deep concealed VMS targets is not clear. The size of a typical VMS target is less than 100 m x 100 m x 50 m, it's a challenge task to find it with large depth. We carried a test in a VMS Pb-Zn deposit using high density 3D AMT with site spacing as 20 m and profile spacing as 40 - 80 m. About 2000 AMT sites were acquired in an area as 2000 m x 1500 m. Then we used a sever with 8 CPUs (Intel Xeon E7-8880 v3, 2.3 GHz, 144 cores), 2048 GB RAM, and 40 TB disk array to invert above 3D AMT sites using integral equation forward modeling and re-weighted conjugated-gradient inversion. The depth of VMS ore body is about 600 m and the size of the ore body is about 100 x 100 x 20m with dip angle about 45 degree. We finds that it's very hard to recover the location and shape of the ore body by 3D AMT inversion even using the data of all AMT sites and frequencies. However, it's possible to recover the location and shape of the deep concealed ore body if we adjust the inversion parameters carefully. A new set of inversion parameter needs to be find for high density 3D AMT data set and the inversion parameters working good for Dublin Secret Model II (DSM 2) is not suitable for our real data. This problem may be caused by different data density and different number of frequency. We find a set of good inversion parameter by comparing the shape and location of ore body with inversion result and trying different inversion parameters. And the application of new inversion parameter in nearby area with high density AMT sites shows that the inversion result is improved greatly.

  11. Ultrafast magnetic vortex core switching driven by the topological inverse Faraday effect.

    PubMed

    Taguchi, Katsuhisa; Ohe, Jun-ichiro; Tatara, Gen

    2012-09-21

    We present a theoretical discovery of an unconventional mechanism of inverse Faraday effect which acts selectively on topological magnetic structures. The effect, topological inverse Faraday effect, is induced by the spin Berry's phase of the magnetic structure when a circularly polarized light is applied. Thus a spin-orbit interaction is not necessary unlike that in the conventional inverse Faraday effect. We demonstrate by numerical simulation that topological inverse Faraday effect realizes ultrafast switching of a magnetic vortex within a switching time of 150 ps without magnetic field.

  12. Megabase-Scale Inversion Polymorphism in the Wild Ancestor of Maize

    PubMed Central

    Fang, Zhou; Pyhäjärvi, Tanja; Weber, Allison L.; Dawe, R. Kelly; Glaubitz, Jeffrey C.; González, José de Jesus Sánchez; Ross-Ibarra, Claudia; Doebley, John; Morrell, Peter L.; Ross-Ibarra, Jeffrey

    2012-01-01

    Chromosomal inversions are thought to play a special role in local adaptation, through dramatic suppression of recombination, which favors the maintenance of locally adapted alleles. However, relatively few inversions have been characterized in population genomic data. On the basis of single-nucleotide polymorphism (SNP) genotyping across a large panel of Zea mays, we have identified an ∼50-Mb region on the short arm of chromosome 1 where patterns of polymorphism are highly consistent with a polymorphic paracentric inversion that captures >700 genes. Comparison to other taxa in Zea and Tripsacum suggests that the derived, inverted state is present only in the wild Z. mays subspecies parviglumis and mexicana and is completely absent in domesticated maize. Patterns of polymorphism suggest that the inversion is ancient and geographically widespread in parviglumis. Cytological screens find little evidence for inversion loops, suggesting that inversion heterozygotes may suffer few crossover-induced fitness consequences. The inversion polymorphism shows evidence of adaptive evolution, including a strong altitudinal cline, a statistical association with environmental variables and phenotypic traits, and a skewed haplotype frequency spectrum for inverted alleles. PMID:22542971

  13. Global moment tensor computation at GFZ Potsdam

    NASA Astrophysics Data System (ADS)

    Saul, J.; Becker, J.; Hanka, W.

    2011-12-01

    As part of its earthquake information service, GFZ Potsdam has started to provide seismic moment tensor solutions for significant earthquakes world-wide. The software used to compute the moment tensors is a GFZ-Potsdam in-house development, which uses the framework of the software SeisComP 3 (Hanka et al., 2010). SeisComP 3 (SC3) is a software package for seismological data acquisition, archival, quality control and analysis. SC3 is developed by GFZ Potsdam with significant contributions from its user community. The moment tensor inversion technique uses a combination of several wave types, time windows and frequency bands depending on magnitude and station distance. Wave types include body, surface and mantle waves as well as the so-called 'W-Phase' (Kanamori and Rivera, 2008). The inversion is currently performed in the time domain only. An iterative centroid search can be performed independently both horizontally and in depth. Moment tensors are currently computed in a semi-automatic fashion. This involves inversions that are performed automatically in near-real time, followed by analyst review prior to publication. The automatic results are quite often good enough to be published without further improvements, sometimes in less than 30 minutes from origin time. In those cases where a manual interaction is still required, the automatic inversion usually does a good job at pre-selecting those traces that are the most relevant for the inversion, keeping the work required for the analyst at a minimum. Our published moment tensors are generally in good agreement with those published by the Global Centroid-Moment-Tensor (GCMT) project for earthquakes above a magnitude of about Mw 5. Additionally we provide solutions for smaller earthquakes above about Mw 4 in Europe, which are normally not analyzed by the GCMT project. We find that for earthquakes above Mw 6, the most robust automatic inversions can usually be obtained using the W-Phase time window. The GFZ earthquake bulletin is located at http://geofon.gfz-potsdam.de/eqinfo For more information on the SeisComP 3 software visit http://www.seiscomp3.org

  14. High-frequency seismic energy radiation from the 2003 Miyagi-Oki, JAPAN, earthquake (M7.0) as revealed from an envelope inversion analysis

    NASA Astrophysics Data System (ADS)

    Nakahara, H.

    2003-12-01

    The 2003 Miyagi-Oki earthquake (M 7.0) took place on May 26, 2003 in the subducting Pacific plate beneath northeastern Japan. The focal depth is around 70km. The focal mechanism is reverse type on a fault plane dipping to the west with a high angle. There was no fatality, fortunately. However, this earthquake caused more than 100 injures, 2000 collapsed houses, and so on. To the south of this focal area by about 50km, an interplate earthquake of M7.5, the Miyagi-Ken-Oki earthquake, is expected to occur in the near future. So the relation between this earthquake and the expected Miyagi-Ken-Oki earthquake attracts public attention. Seismic-energy distribution on earthquake fault planes estimated by envelope inversion analyses can contribute to better understanding of the earthquake source process. For moderate to large earthquakes, seismic energy in frequencies higher than 1 Hz is sometimes much larger than a level expected from the omega-squared model with source parameters estimated by lower-frequency analyses. Therefore, an accurate estimation of seismic energy in such high frequencies has significant importance on estimation of dynamic source parameters such as the seismic energy or the apparent stress. In this study, we execute an envelope inversion analysis based on the method by Nakahara et al. (1998) and clarify the spatial distribution of high-frequency seismic energy radiation on the fault plane of this earthquake. We use three-component sum of mean squared velocity seismograms multiplied by a density of earth medium, which is called envelopes here, for the envelope inversion analysis. Four frequency bands of 1-2, 2-4, 4-8, and 8-16 Hz are adopted. We use envelopes in the time window from the onset of S waves to the lapse time of 51.2 sec. Green functions of envelopes representing the energy propagation process through a scattering medium are calculated based on the radiative transfer theory, which are characterized by parameters of scattering attenuation and intrinsic absorption. We use the values obtained for the northeastern Japan (Sakurai, 1995). We assume the fault plane as follows: strike=193,a, dip=69,a, rake=87,a, length=30km, width=25km with referrence to a waveform inversion analysis in low-frequencies (e.g. Yagi, 2003). We divide this fault plane into 25 subfaults, each of which is a 5km x 5km square. Rupture velocity is assumed to be constant. Seismic energy is radiated from a point source as soon as the rupture front passes the center of each subfault. Time function of energy radiation is assumed as a box-car function. The amount of seismic energy from all the subfaults and site amplification factors for all the stations are estimated by the envelope inversion method. Rupture velocity and the duration time of a box-car function should be estimated by a grid search. Theoretical envelopes calculated with best-fit parameters generally fit to observed ones. The rupture velocity and duration time were estimated as 3.8 km/s and 1.6 sec, respectively. The high-frequency seismic energy was found to be radiated mainly from two spots on the fault plane: The first one is around the initial rupture point and the second is the northern part of the fault plane. These two spots correspond to observed two peaks on envelopes. Amount of seismic energy increases with increasing frequency in the 1-16Hz band, which contradicts an expectation from the omega-squared model. Therefore, stronger radiation of higher-frequency seismic energy is a prominent character of this earthquake. Acknowledgements: We used strong-motion seismograms recorded by the K-NET and KiK-net of NIED, JAPAN.

  15. Impact of heart rate variability, a marker for cardiac health, on lupus disease activity.

    PubMed

    Thanou, Aikaterini; Stavrakis, Stavros; Dyer, John W; Munroe, Melissa E; James, Judith A; Merrill, Joan T

    2016-09-02

    Decreased heart rate variability (HRV) is associated with adverse outcomes in cardiovascular diseases and has been observed in patients with systemic lupus erythematosus (SLE). We examined the relationship of HRV with SLE disease activity and selected cytokine pathways. Fifty-three patients from the Oklahoma Lupus Cohort were evaluated at two visits each. Clinical assessments included the Systemic Lupus Erythematosus Disease Activity Index (SLEDAI), British Isles Lupus Assessment Group (BILAG) index, physician global assessment (PGA), and Safety of Estrogens in Lupus Erythematosus National Assessment-SLEDAI Flare Index. HRV was assessed with a 5-minute electrocardiogram, and the following HRV parameters were calculated: square root of the mean of the squares of differences between adjacent NN intervals (RMSSD), percentage of pairs of adjacent NN intervals differing by more than 50 milliseconds (pNN50), high-frequency power (HF power), and low frequency to high frequency (LF/HF) ratio, which reflects sympathetic/vagal balance. Plasma cytokine levels were measured with a multiplex, bead-based immunoassay. Serum B lymphocyte stimulator (BLyS) and a proliferation-inducing ligand (APRIL) were measured with an enzyme-linked immunosorbent assay. Linear regression analysis was applied. Baseline HRV (pNN50, HF power, LF/HF ratio) was inversely related to disease activity (BILAG, PGA) and flare. Changes in RMSSD between visits were inversely related to changes in SLEDAI (p = 0.007). Age, caffeine, tobacco and medication use had no impact on HRV. Plasma soluble tumor necrosis factor receptor II (sTNFRII) and monokine induced by interferon gamma (MIG) were inversely related with all baseline measures of HRV (p = 0.039 to <0.001). Plasma stem cell factor (SCF), interleukin (IL)-1 receptor antagonist (IL-1RA), and IL-15 showed similar inverse relationships with baseline HRV, and weaker trends were observed for interferon (IFN)-α, interferon gamma-induced protein (IP)-10, and serum BLyS. Changes in the LF/HF ratio between visits were also associated with changes in sTNFRII (p = 0.021), MIG (p = 0.003), IFN-α (p = 0.012), SCF (p = 0.001), IL-1RA (p = 0.023), and IL-15 (p = 0.010). On the basis of multivariate linear regression, MIG was an independent predictor of baseline HRV after adjusting for plasma IL-1RA, SCF, IFN-α, IP-10, and serum BLyS. In a similar model, the sTNFRII impact remained significant after adjusting for the same variables. Impaired HRV, particularly the LF/HF ratio, is associated with lupus disease activity and several cytokines related to IFN type II and TNF pathways. The strongest association was with MIG and sTNFRII, expanding previous immune connections of vagal signaling.

  16. 2D and 3D separate and joint inversion of airborne ZTEM and ground AMT data: Synthetic model studies

    NASA Astrophysics Data System (ADS)

    Sasaki, Yutaka; Yi, Myeong-Jong; Choi, Jihyang

    2014-05-01

    The ZTEM (Z-axis Tipper Electromagnetic) method measures naturally occurring audio-frequency magnetic fields and obtains the tipper function that defines the relationship among the three components of the magnetic field. Since the anomalous tipper responses are caused by the presence of lateral resistivity variations, the ZTEM survey is most suited for detecting and delineating conductive bodies extending to considerable depths, such as graphitic dykes encountered in the exploration of unconformity type uranium deposit. Our simulations shows that inversion of ZTEM data can detect reasonably well multiple conductive dykes placed 1 km apart. One important issue regarding ZTEM inversion is the effect of the initial model, because homogeneous half-space and (1D) layered structures produce no responses. For the 2D model with multiple conductive dykes, the inversion results were useful for locating the dykes even when the initial model was not close to the true background resistivity. For general 3D structures, however, the resolution of the conductive bodies can be reduced considerably depending on the initial model. This is because the tipper magnitudes from 3D conductors are smaller due to boundary charges than the 2D responses. To alleviate this disadvantage of ZTEM surveys, we combined ZTEM and audio-frequency magnetotelluric (AMT) data. Inversion of sparse AMT data was shown to be effective in providing a good initial model for ZTEM inversion. Moreover, simultaneously inverting both data sets led to better results than the sequential approach by enabling to identify structural features that were difficult to resolve from the individual data sets.

  17. Jump-and-return sandwiches: A new family of binomial-like selective inversion sequences with improved performance.

    PubMed

    Brenner, Tom; Chen, Johnny; Stait-Gardner, Tim; Zheng, Gang; Matsukawa, Shingo; Price, William S

    2018-03-01

    A new family of binomial-like inversion sequences, named jump-and-return sandwiches (JRS), has been developed by inserting a binomial-like sequence into a standard jump-and-return sequence, discovered through use of a stochastic Genetic Algorithm optimisation. Compared to currently used binomial-like inversion sequences (e.g., 3-9-19 and W5), the new sequences afford wider inversion bands and narrower non-inversion bands with an equal number of pulses. As an example, two jump-and-return sandwich 10-pulse sequences achieved 95% inversion at offsets corresponding to 9.4% and 10.3% of the non-inversion band spacing, compared to 14.7% for the binomial-like W5 inversion sequence, i.e., they afforded non-inversion bands about two thirds the width of the W5 non-inversion band. Copyright © 2018 Elsevier Inc. All rights reserved.

  18. The 1994 Northridge, California, earthquake: Investigation of rupture velocity, risetime, and high-frequency radiation

    USGS Publications Warehouse

    Hartzell, S.; Liu, P.; Mendoza, C.

    1996-01-01

    A hybrid global search algorithm is used to solve the nonlinear problem of calculating slip amplitude, rake, risetime, and rupture time on a finite fault. Thirty-five strong motion velocity records are inverted by this method over the frequency band from 0.1 to 1.0 Hz for the Northridge earthquake. Four regions of larger-amplitude slip are identified: one near the hypocenter at a depth of 17 km, a second west of the hypocenter at about the same depth, a third updip from the hypocenter at a depth of 10 km, and a fourth updip from the hypocenter and to the northwest. The results further show an initial fast rupture with a velocity of 2.8 to 3.0 km/s followed by a slow termination of the rupture with velocities of 2.0 to 2.5 km/s. The initial energetic rupture phase lasts for 3 s, extending out 10 km from the hypocenter. Slip near the hypocenter has a short risetime of 0.5 s, which increases to 1.5 s for the major slip areas removed from the hypocentral region. The energetic rupture phase is also shown to be the primary source of high-frequency radiation (1-15 Hz) by an inversion of acceleration envelopes. The same global search algorithm is used in the envelope inversion to calculate high-frequency radiation intensity on the fault and rupture time. The rupture timing from the low- and high-frequency inversions is similar, indicating that the high frequencies are produced primarily at the mainshock rupture front. Two major sources of high-frequency radiation are identified within the energetic rupture phase, one at the hypocenter and another deep source to the west of the hypocenter. The source at the hypocenter is associated with the initiation of rupture and the breaking of a high-stress-drop asperity and the second is associated with stopping of the rupture in a westerly direction.

  19. The Effects of Sediment Properties on Low Frequency Acoustic Propagation

    DTIC Science & Technology

    2015-09-30

    1 DISTRIBUTION STATEMENT A. Approved for public release; distribution is unlimited. The Effects of Sediment Properties on Low Frequency...investigations have indicated that water-borne acoustic arrival properties such as their Airy Phase are sensitive to sediment shear properties. Our major...goals of our research are to: • Improve inversion schemes for the estimation of sediment geoacoustic properties using low frequency broadband

  20. Pressure attenuation during high-frequency airway clearance therapy across different size endotracheal tubes: An in vitro study.

    PubMed

    Smallwood, Craig D; Bullock, Kevin J; Gouldstone, Andrew

    2016-08-01

    High-frequency airway clearance therapy is a positive pressure secretion clearance modality used in pediatric and adult applications. However, pressure attenuation across different size endotracheal tubes (ETT) has not been adequately described. This study quantifies attenuation in an in vitro model. The MetaNeb® System was used to deliver high-frequency pressure pulses to 3.0, 4.0, 6.0 and 8.0mm ID ETTs connected to a test lung during mechanical ventilation. The experimental setup included a 3D-printed trachea model and imbedded pressure sensors. The pressure attenuation (Patt%) was calculated: Patt%=[(Pproximal-Pdistal)/Pproximal]x100. The effect of pulse frequency on Pdistal and Pproximal was quantified. Patt% was inversely and linearly related to ETT ID and (y=-7.924x+74.36; R(2)=0.9917, P=.0042 for 4.0Hz pulse frequency and y=-7.382+9.445, R(2)=0.9964, P=.0018 for 3.0Hz pulse frequency). Patt% across the 3.0, 4.0, 6.0 and 8.0mm I.D. ETTs was 48.88±10.25%, 40.87±5.22%, 27.97±5.29%, and 9.90±1.9% respectively. Selecting the 4.0Hz frequency mode demonstrated higher Pproximal and Pdistal compared to the 3.0Hz frequency mode (P=.0049 and P=.0065). Observed Pdistal was <30cmH2O for all experiments. In an in vitro model, pressure attenuation was linearly related to the inner diameter of the endotracheal tube; with decreasing attenuation as the ETT size increased. Copyright © 2016 Elsevier Inc. All rights reserved.

  1. Direct and Inverse Techniques of Guided-Mode Resonance Filters Designs

    NASA Technical Reports Server (NTRS)

    Tibuleac, Sorin; Magnusson, Robert; Maldonado, Theresa A.; Zuffada, Cinzia

    1997-01-01

    Guided-mode resonances arise in single or multilayer waveguides where one or more homogeneous layers are replaced by diffraction gratings (Fig. 1.) The diffractive element enables an electromagnetic wave incident on a waveguide grating to be coupled to the waveguide modes supportable by the structure in the absence of the modulation (i.e. the difference between the high and low dielectric constants of the grating) at specific values of the wavelength and incident angle. The periodic modulation of the guide makes the structure leaky, preventing sustained propagation of modes in the waveguide and coupling the waves out into the substrate and cover. As the wavelength is varied around resonance a rapid variation in the intensities of the external propagating waves occurs. By selecting a grating period small enough to eliminate the higher-order propagating waves, an increase in the zero-order intensities up to 100% can result. The pronounced frequency selectivity of guided-mode resonances in dielectric waveguide gratings can be applied to design high-efficiency reflection and transmission filters [1-3].

  2. Selecting an Informative/Discriminating Multivariate Response for Inverse Prediction

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Thomas, Edward V.; Lewis, John. R.; Anderson-Cook, Christine Michaela

    The inverse prediction is important in a variety of scientific and engineering applications, such as to predict properties/characteristics of an object by using multiple measurements obtained from it. Inverse prediction can be accomplished by inverting parameterized forward models that relate the measurements (responses) to the properties/characteristics of interest. Sometimes forward models are computational/science based; but often, forward models are empirically based response surface models, obtained by using the results of controlled experimentation. For empirical models, it is important that the experiments provide a sound basis to develop accurate forward models in terms of the properties/characteristics (factors). And while nature dictatesmore » the causal relationships between factors and responses, experimenters can control the complexity, accuracy, and precision of forward models constructed via selection of factors, factor levels, and the set of trials that are performed. Recognition of the uncertainty in the estimated forward models leads to an errors-in-variables approach for inverse prediction. The forward models (estimated by experiments or science based) can also be used to analyze how well candidate responses complement one another for inverse prediction over the range of the factor space of interest. Furthermore, one may find that some responses are complementary, redundant, or noninformative. Simple analysis and examples illustrate how an informative and discriminating subset of responses could be selected among candidates in cases where the number of responses that can be acquired during inverse prediction is limited by difficulty, expense, and/or availability of material.« less

  3. Selecting an Informative/Discriminating Multivariate Response for Inverse Prediction

    DOE PAGES

    Thomas, Edward V.; Lewis, John. R.; Anderson-Cook, Christine Michaela; ...

    2017-07-01

    The inverse prediction is important in a variety of scientific and engineering applications, such as to predict properties/characteristics of an object by using multiple measurements obtained from it. Inverse prediction can be accomplished by inverting parameterized forward models that relate the measurements (responses) to the properties/characteristics of interest. Sometimes forward models are computational/science based; but often, forward models are empirically based response surface models, obtained by using the results of controlled experimentation. For empirical models, it is important that the experiments provide a sound basis to develop accurate forward models in terms of the properties/characteristics (factors). And while nature dictatesmore » the causal relationships between factors and responses, experimenters can control the complexity, accuracy, and precision of forward models constructed via selection of factors, factor levels, and the set of trials that are performed. Recognition of the uncertainty in the estimated forward models leads to an errors-in-variables approach for inverse prediction. The forward models (estimated by experiments or science based) can also be used to analyze how well candidate responses complement one another for inverse prediction over the range of the factor space of interest. Furthermore, one may find that some responses are complementary, redundant, or noninformative. Simple analysis and examples illustrate how an informative and discriminating subset of responses could be selected among candidates in cases where the number of responses that can be acquired during inverse prediction is limited by difficulty, expense, and/or availability of material.« less

  4. A space-frequency multiplicative regularization for force reconstruction problems

    NASA Astrophysics Data System (ADS)

    Aucejo, M.; De Smet, O.

    2018-05-01

    Dynamic forces reconstruction from vibration data is an ill-posed inverse problem. A standard approach to stabilize the reconstruction consists in using some prior information on the quantities to identify. This is generally done by including in the formulation of the inverse problem a regularization term as an additive or a multiplicative constraint. In the present article, a space-frequency multiplicative regularization is developed to identify mechanical forces acting on a structure. The proposed regularization strategy takes advantage of one's prior knowledge of the nature and the location of excitation sources, as well as that of their spectral contents. Furthermore, it has the merit to be free from the preliminary definition of any regularization parameter. The validity of the proposed regularization procedure is assessed numerically and experimentally. It is more particularly pointed out that properly exploiting the space-frequency characteristics of the excitation field to identify can improve the quality of the force reconstruction.

  5. Optimization of contrast resolution by genetic algorithm in ultrasound tissue harmonic imaging.

    PubMed

    Ménigot, Sébastien; Girault, Jean-Marc

    2016-09-01

    The development of ultrasound imaging techniques such as pulse inversion has improved tissue harmonic imaging. Nevertheless, no recommendation has been made to date for the design of the waveform transmitted through the medium being explored. Our aim was therefore to find automatically the optimal "imaging" wave which maximized the contrast resolution without a priori information. To overcome assumption regarding the waveform, a genetic algorithm investigated the medium thanks to the transmission of stochastic "explorer" waves. Moreover, these stochastic signals could be constrained by the type of generator available (bipolar or arbitrary). To implement it, we changed the current pulse inversion imaging system by including feedback. Thus the method optimized the contrast resolution by adaptively selecting the samples of the excitation. In simulation, we benchmarked the contrast effectiveness of the best found transmitted stochastic commands and the usual fixed-frequency command. The optimization method converged quickly after around 300 iterations in the same optimal area. These results were confirmed experimentally. In the experimental case, the contrast resolution measured on a radiofrequency line could be improved by 6% with a bipolar generator and it could still increase by 15% with an arbitrary waveform generator. Copyright © 2016 Elsevier B.V. All rights reserved.

  6. Soliton triads ensemble in frequency conversion: from inverse scattering theory to experimental observation.

    PubMed

    Baronio, Fabio; Andreana, Marco; Conforti, Matteo; Manili, Gabriele; Couderc, Vincent; De Angelis, Costantino; Barthélémy, Alain

    2011-07-04

    We consider the spectral theory of three-wave interactions to predict the initiation, formation and dynamics of an ensemble of bright-dark-bright soliton triads in frequency conversion processes. Spatial observation of non-interacting triads ensemble in a KTP crystal confirms theoretical prediction and numerical simulations.

  7. Obtaining eigensolutions for multiple frequency ranges in a single NASTRAN execution

    NASA Technical Reports Server (NTRS)

    Pamidi, P. R.; Brown, W. K.

    1990-01-01

    A novel and general procedure for obtaining eigenvalues and eigenvectors for multiple frequency ranges in a single NASTRAN execution is presented. The scheme is applicable to normal modes analyzes employing the FEER and Inverse Power methods of eigenvalue extraction. The procedure is illustrated by examples.

  8. Cyclotron resonance of the magnetic ratchet effect and second harmonic generation in bilayer graphene

    NASA Astrophysics Data System (ADS)

    Kheirabadi, Narjes; McCann, Edward; Fal'ko, Vladimir I.

    2018-02-01

    We model the magnetic ratchet effect in bilayer graphene in which a dc electric current is produced by an ac electric field of frequency ω in the presence of a steady in-plane magnetic field and inversion-symmetry breaking. In bilayer graphene, the ratchet effect is tunable by an external metallic gate which breaks inversion symmetry. For zero in-plane magnetic field, we show that trigonal warping and inversion-symmetry breaking are able to produce a large dc valley current, but not a nonzero total dc charge current. For the magnetic ratchet in a tilted magnetic field, the perpendicular field component induces cyclotron motion with frequency ωc and we find that the dc current displays cyclotron resonance at ωc=ω , although this peak in the current is actually smaller than its value at ωc=0 . Second harmonic generation, however, is greatly enhanced by resonances at ωc=ω and ωc=2 ω for which the current is generally much larger than at ωc=0 .

  9. Three-dimensional silicon inverse photonic quasicrystals for infrared wavelengths.

    PubMed

    Ledermann, Alexandra; Cademartiri, Ludovico; Hermatschweiler, Martin; Toninelli, Costanza; Ozin, Geoffrey A; Wiersma, Diederik S; Wegener, Martin; von Freymann, Georg

    2006-12-01

    Quasicrystals are a class of lattices characterized by a lack of translational symmetry. Nevertheless, the points of the lattice are deterministically arranged, obeying rotational symmetry. Thus, we expect properties that are different from both crystals and glasses. Indeed, naturally occurring electronic quasicrystals (for example, AlPdMn metal alloys) show peculiar electronic, vibrational and physico-chemical properties. Regarding artificial quasicrystals for electromagnetic waves, three-dimensional (3D) structures have recently been realized at GHz frequencies and 2D structures have been reported for the near-infrared region. Here, we report on the first fabrication and characterization of 3D quasicrystals for infrared frequencies. Using direct laser writing combined with a silicon inversion procedure, we achieve high-quality silicon inverse icosahedral structures. Both polymeric and silicon quasicrystals are characterized by means of electron microscopy and visible-light Laue diffraction. The diffraction patterns of structures with a local five-fold real-space symmetry axis reveal a ten-fold symmetry as required by theory for 3D structures.

  10. Spin pumping and inverse spin Hall voltages from dynamical antiferromagnets

    NASA Astrophysics Data System (ADS)

    Johansen, Øyvind; Brataas, Arne

    2017-06-01

    Dynamical antiferromagnets can pump spins into adjacent conductors. The high antiferromagnetic resonance frequencies represent a challenge for experimental detection, but magnetic fields can reduce these resonance frequencies. We compute the ac and dc inverse spin Hall voltages resulting from dynamical spin excitations as a function of a magnetic field along the easy axis and the polarization of the driving ac magnetic field perpendicular to the easy axis. We consider the insulating antiferromagnets MnF2,FeF2, and NiO. Near the spin-flop transition, there is a significant enhancement of the dc spin pumping and inverse spin Hall voltage for the uniaxial antiferromagnets MnF2 and FeF2. In the uniaxial antiferromagnets it is also found that the ac spin pumping is independent of the external magnetic field when the driving field has the optimal circular polarization. In the biaxial NiO, the voltages are much weaker, and there is no spin-flop enhancement of the dc component.

  11. New Inversion and Interpretation of Public-Domain Electromagnetic Survey Data from Selected Areas in Alaska

    NASA Astrophysics Data System (ADS)

    Smith, B. D.; Kass, A.; Saltus, R. W.; Minsley, B. J.; Deszcz-Pan, M.; Bloss, B. R.; Burns, L. E.

    2013-12-01

    Public-domain airborne geophysical surveys (combined electromagnetics and magnetics), mostly collected for and released by the State of Alaska, Division of Geological and Geophysical Surveys (DGGS), are a unique and valuable resource for both geologic interpretation and geophysical methods development. A new joint effort by the US Geological Survey (USGS) and the DGGS aims to add value to these data through the application of novel advanced inversion methods and through innovative and intuitive display of data: maps, profiles, voxel-based models, and displays of estimated inversion quality and confidence. Our goal is to make these data even more valuable for interpretation of geologic frameworks, geotechnical studies, and cryosphere studies, by producing robust estimates of subsurface resistivity that can be used by non-geophysicists. The available datasets, which are available in the public domain, include 39 frequency-domain electromagnetic datasets collected since 1993, and continue to grow with 5 more data releases pending in 2013. The majority of these datasets were flown for mineral resource purposes, with one survey designed for infrastructure analysis. In addition, several USGS datasets are included in this study. The USGS has recently developed new inversion methodologies for airborne EM data and have begun to apply these and other new techniques to the available datasets. These include a trans-dimensional Markov Chain Monte Carlo technique, laterally-constrained regularized inversions, and deterministic inversions which include calibration factors as a free parameter. Incorporation of the magnetic data as an additional constraining dataset has also improved the inversion results. Processing has been completed in several areas, including Fortymile and the Alaska Highway surveys, and continues in others such as the Styx River and Nome surveys. Utilizing these new techniques, we provide models beyond the apparent resistivity maps supplied by the original contractors, allowing us to produce a variety of products, such as maps of resistivity as a function of depth or elevation, cross section maps, and 3D voxel models, which have been treated consistently both in terms of processing and error analysis throughout the state. These products facilitate a more fruitful exchange between geologists and geophysicists and a better understanding of uncertainty, and the process results in iterative development and improvement of geologic models, both on small and large scales.

  12. Bayesian inference in geomagnetism

    NASA Technical Reports Server (NTRS)

    Backus, George E.

    1988-01-01

    The inverse problem in empirical geomagnetic modeling is investigated, with critical examination of recently published studies. Particular attention is given to the use of Bayesian inference (BI) to select the damping parameter lambda in the uniqueness portion of the inverse problem. The mathematical bases of BI and stochastic inversion are explored, with consideration of bound-softening problems and resolution in linear Gaussian BI. The problem of estimating the radial magnetic field B(r) at the earth core-mantle boundary from surface and satellite measurements is then analyzed in detail, with specific attention to the selection of lambda in the studies of Gubbins (1983) and Gubbins and Bloxham (1985). It is argued that the selection method is inappropriate and leads to lambda values much larger than those that would result if a reasonable bound on the heat flow at the CMB were assumed.

  13. EDITORIAL: Inverse Problems in Engineering

    NASA Astrophysics Data System (ADS)

    West, Robert M.; Lesnic, Daniel

    2007-01-01

    Presented here are 11 noteworthy papers selected from the Fifth International Conference on Inverse Problems in Engineering: Theory and Practice held in Cambridge, UK during 11-15 July 2005. The papers have been peer-reviewed to the usual high standards of this journal and the contributions of reviewers are much appreciated. The conference featured a good balance of the fundamental mathematical concepts of inverse problems with a diverse range of important and interesting applications, which are represented here by the selected papers. Aspects of finite-element modelling and the performance of inverse algorithms are investigated by Autrique et al and Leduc et al. Statistical aspects are considered by Emery et al and Watzenig et al with regard to Bayesian parameter estimation and inversion using particle filters. Electrostatic applications are demonstrated by van Berkel and Lionheart and also Nakatani et al. Contributions to the applications of electrical techniques and specifically electrical tomographies are provided by Wakatsuki and Kagawa, Kim et al and Kortschak et al. Aspects of inversion in optical tomography are investigated by Wright et al and Douiri et al. The authors are representative of the worldwide interest in inverse problems relating to engineering applications and their efforts in producing these excellent papers will be appreciated by many readers of this journal.

  14. Parallel three-dimensional magnetotelluric inversion using adaptive finite-element method. Part I: theory and synthetic study

    NASA Astrophysics Data System (ADS)

    Grayver, Alexander V.

    2015-07-01

    This paper presents a distributed magnetotelluric inversion scheme based on adaptive finite-element method (FEM). The key novel aspect of the introduced algorithm is the use of automatic mesh refinement techniques for both forward and inverse modelling. These techniques alleviate tedious and subjective procedure of choosing a suitable model parametrization. To avoid overparametrization, meshes for forward and inverse problems were decoupled. For calculation of accurate electromagnetic (EM) responses, automatic mesh refinement algorithm based on a goal-oriented error estimator has been adopted. For further efficiency gain, EM fields for each frequency were calculated using independent meshes in order to account for substantially different spatial behaviour of the fields over a wide range of frequencies. An automatic approach for efficient initial mesh design in inverse problems based on linearized model resolution matrix was developed. To make this algorithm suitable for large-scale problems, it was proposed to use a low-rank approximation of the linearized model resolution matrix. In order to fill a gap between initial and true model complexities and resolve emerging 3-D structures better, an algorithm for adaptive inverse mesh refinement was derived. Within this algorithm, spatial variations of the imaged parameter are calculated and mesh is refined in the neighborhoods of points with the largest variations. A series of numerical tests were performed to demonstrate the utility of the presented algorithms. Adaptive mesh refinement based on the model resolution estimates provides an efficient tool to derive initial meshes which account for arbitrary survey layouts, data types, frequency content and measurement uncertainties. Furthermore, the algorithm is capable to deliver meshes suitable to resolve features on multiple scales while keeping number of unknowns low. However, such meshes exhibit dependency on an initial model guess. Additionally, it is demonstrated that the adaptive mesh refinement can be particularly efficient in resolving complex shapes. The implemented inversion scheme was able to resolve a hemisphere object with sufficient resolution starting from a coarse discretization and refining mesh adaptively in a fully automatic process. The code is able to harness the computational power of modern distributed platforms and is shown to work with models consisting of millions of degrees of freedom. Significant computational savings were achieved by using locally refined decoupled meshes.

  15. Estimation of near-surface shear-wave velocities and quality factors using multichannel analysis of surface-wave methods

    NASA Astrophysics Data System (ADS)

    Xia, Jianghai

    2014-04-01

    This overview article gives a picture of multichannel analysis of high-frequency surface (Rayleigh and Love) waves developed mainly by research scientists at the Kansas Geological Survey, the University of Kansas and China University of Geosciences (Wuhan) during the last eighteen years by discussing dispersion imaging techniques, inversion systems, and real-world examples. Shear (S)-wave velocities of near-surface materials can be derived from inverting the dispersive phase velocities of high-frequency surface waves. Multichannel analysis of surface waves—MASW used phase information of high-frequency Rayleigh waves recorded on vertical component geophones to determine near-surface S-wave velocities. The differences between MASW results and direct borehole measurements are approximately 15% or less and random. Studies show that inversion with higher modes and the fundamental mode simultaneously can increase model resolution and an investigation depth. Multichannel analysis of Love waves—MALW used phase information of high-frequency Love waves recorded on horizontal (perpendicular to the direction of wave propagation) component geophones to determine S-wave velocities of shallow materials. Because of independence of compressional (P)-wave velocity, the MALW method has some attractive advantages, such as 1) Love-wave dispersion curves are simpler than Rayleigh wave's; 2) dispersion images of Love-wave energy have a higher signal to noise ratio and more focused than those generated from Rayleigh waves; and 3) inversion of Love-wave dispersion curves is less dependent on initial models and more stable than Rayleigh waves.

  16. Pseudo-dynamic source characterization accounting for rough-fault effects

    NASA Astrophysics Data System (ADS)

    Galis, Martin; Thingbaijam, Kiran K. S.; Mai, P. Martin

    2016-04-01

    Broadband ground-motion simulations, ideally for frequencies up to ~10Hz or higher, are important for earthquake engineering; for example, seismic hazard analysis for critical facilities. An issue with such simulations is realistic generation of radiated wave-field in the desired frequency range. Numerical simulations of dynamic ruptures propagating on rough faults suggest that fault roughness is necessary for realistic high-frequency radiation. However, simulations of dynamic ruptures are too expensive for routine applications. Therefore, simplified synthetic kinematic models are often used. They are usually based on rigorous statistical analysis of rupture models inferred by inversions of seismic and/or geodetic data. However, due to limited resolution of the inversions, these models are valid only for low-frequency range. In addition to the slip, parameters such as rupture-onset time, rise time and source time functions are needed for complete spatiotemporal characterization of the earthquake rupture. But these parameters are poorly resolved in the source inversions. To obtain a physically consistent quantification of these parameters, we simulate and analyze spontaneous dynamic ruptures on rough faults. First, by analyzing the impact of fault roughness on the rupture and seismic radiation, we develop equivalent planar-fault kinematic analogues of the dynamic ruptures. Next, we investigate the spatial interdependencies between the source parameters to allow consistent modeling that emulates the observed behavior of dynamic ruptures capturing the rough-fault effects. Based on these analyses, we formulate a framework for pseudo-dynamic source model, physically consistent with the dynamic ruptures on rough faults.

  17. Three-dimensional magnetotelluric inversion including topography using deformed hexahedral edge finite elements, direct solvers and data space Gauss-Newton, parallelized on SMP computers

    NASA Astrophysics Data System (ADS)

    Kordy, M. A.; Wannamaker, P. E.; Maris, V.; Cherkaev, E.; Hill, G. J.

    2014-12-01

    We have developed an algorithm for 3D simulation and inversion of magnetotelluric (MT) responses using deformable hexahedral finite elements that permits incorporation of topography. Direct solvers parallelized on symmetric multiprocessor (SMP), single-chassis workstations with large RAM are used for the forward solution, parameter jacobians, and model update. The forward simulator, jacobians calculations, as well as synthetic and real data inversion are presented. We use first-order edge elements to represent the secondary electric field (E), yielding accuracy O(h) for E and its curl (magnetic field). For very low frequency or small material admittivity, the E-field requires divergence correction. Using Hodge decomposition, correction may be applied after the forward solution is calculated. It allows accurate E-field solutions in dielectric air. The system matrix factorization is computed using the MUMPS library, which shows moderately good scalability through 12 processor cores but limited gains beyond that. The factored matrix is used to calculate the forward response as well as the jacobians of field and MT responses using the reciprocity theorem. Comparison with other codes demonstrates accuracy of our forward calculations. We consider a popular conductive/resistive double brick structure and several topographic models. In particular, the ability of finite elements to represent smooth topographic slopes permits accurate simulation of refraction of electromagnetic waves normal to the slopes at high frequencies. Run time tests indicate that for meshes as large as 150x150x60 elements, MT forward response and jacobians can be calculated in ~2.5 hours per frequency. For inversion, we implemented data space Gauss-Newton method, which offers reduction in memory requirement and a significant speedup of the parameter step versus model space approach. For dense matrix operations we use tiling approach of PLASMA library, which shows very good scalability. In synthetic inversions we examine the importance of including the topography in the inversion and we test different regularization schemes using weighted second norm of model gradient as well as inverting for a static distortion matrix following Miensopust/Avdeeva approach. We also apply our algorithm to invert MT data collected at Mt St Helens.

  18. Diagnostic Characteristics of Submesoscale Coastal Surface Currents

    NASA Astrophysics Data System (ADS)

    Soh, Hyun Sup; Kim, Sung Yong

    2018-03-01

    Submesoscale kinetic energy (KE) spectra and fluxes at the length scales ranging from 2 to 25 km are estimated from hourly and O(1) km-scale coastal surface current maps observed from shore-based high-frequency radars off southern San Diego. The one-dimensional wave number-domain KE spectra of the surface currents have decay slopes between k-2 and k-3 at a wave number (k) of 0.5 km-1. The KE spectra exhibit anisotropy associated with anisotropic circulation, which is constrained by the shoreline and bottom bathymetry. Moreover, the KE spectra exhibit weak seasonality related to the regional submesoscale eddies and low-frequency circulation with weak seasonal variability. The estimated KE fluxes are categorized into four cases of purely forward cascades and inverse cascades at all wave numbers, inverse-then-forward cascades with a single zero-crossing within the range of wave numbers (0.04 to 0.5 km-1), and residuals, which account for approximately 33%, 39%, 19%, and 9% of the total number of realizations, respectively. An injection scale where forward enstrophy cascade and inverse energy cascade occur is estimated to be 5 to 10 km from the cases of the inverse-then-forward cascade, which is consistent with the length scales of the regional submesoscale eddies. Thus, the regional submesoscale processes are initiated by surface frontogenesis due to the weak seasonal low-frequency surface circulation and topography-related currents, then maintained by baroclinic instabilities associated with the seasonal mixed layer and O(10) km-scale submesoscale eddies with weak seasonal variability.

  19. Elastic full waveform inversion based on the homogenization method: theoretical framework and 2-D numerical illustrations

    NASA Astrophysics Data System (ADS)

    Capdeville, Yann; Métivier, Ludovic

    2018-05-01

    Seismic imaging is an efficient tool to investigate the Earth interior. Many of the different imaging techniques currently used, including the so-called full waveform inversion (FWI), are based on limited frequency band data. Such data are not sensitive to the true earth model, but to a smooth version of it. This smooth version can be related to the true model by the homogenization technique. Homogenization for wave propagation in deterministic media with no scale separation, such as geological media, has been recently developed. With such an asymptotic theory, it is possible to compute an effective medium valid for a given frequency band such that effective waveforms and true waveforms are the same up to a controlled error. In this work we make the link between limited frequency band inversion, mainly FWI, and homogenization. We establish the relation between a true model and an FWI result model. This relation is important for a proper interpretation of FWI images. We numerically illustrate, in the 2-D case, that an FWI result is at best the homogenized version of the true model. Moreover, it appears that the homogenized FWI model is quite independent of the FWI parametrization, as long as it has enough degrees of freedom. In particular, inverting for the full elastic tensor is, in each of our tests, always a good choice. We show how the homogenization can help to understand FWI behaviour and help to improve its robustness and convergence by efficiently constraining the solution space of the inverse problem.

  20. Projected change in characteristics of near surface temperature inversions for southeast Australia

    NASA Astrophysics Data System (ADS)

    Ji, Fei; Evans, Jason Peter; Di Luca, Alejandro; Jiang, Ningbo; Olson, Roman; Fita, Lluis; Argüeso, Daniel; Chang, Lisa T.-C.; Scorgie, Yvonne; Riley, Matt

    2018-05-01

    Air pollution has significant impacts on human health. Temperature inversions, especially near surface temperature inversions, can amplify air pollution by preventing convective movements and trapping pollutants close to the ground, thus decreasing air quality and increasing health issues. This effect of temperature inversions implies that trends in their frequency, strength and duration can have important implications for air quality. In this study, we evaluate the ability of three reanalysis-driven high-resolution regional climate model (RCM) simulations to represent near surface inversions at 9 sounding sites in southeast Australia. Then we use outputs of 12 historical and future RCM simulations (each with three time periods: 1990-2009, 2020-2039, and 2060-2079) from the NSW/ACT (New South Wales/Australian Capital Territory) Regional Climate Modelling (NARCliM) project to investigate changes in near surface temperature inversions. The results show that there is a substantial increase in the strength of near surface temperature inversions over southeast Australia which suggests that future inversions may intensify poor air quality events. Near surface inversions and their future changes have clear seasonal and diurnal variations. The largest differences between simulations are associated with the driving GCMs, suggesting that the large-scale circulation plays a dominant role in near surface inversion strengths.

  1. Following the footprints of polymorphic inversions on SNP data: from detection to association tests

    PubMed Central

    Cáceres, Alejandro; González, Juan R.

    2015-01-01

    Inversion polymorphisms have important phenotypic and evolutionary consequences in humans. Two different methodologies have been used to infer inversions from SNP dense data, enabling the use of large cohorts for their study. One approach relies on the differences in linkage disequilibrium across breakpoints; the other one captures the internal haplotype groups that tag the inversion status of chromosomes. In this article, we assessed the convergence of the two methods in the detection of 20 human inversions that have been reported in the literature. The methods converged in four inversions including inv-8p23, for which we studied its association with low-BMI in American children. Using a novel haplotype tagging method with control on inversion ancestry, we computed the frequency of inv-8p23 in two American cohorts and observed inversion haplotype admixture. Accounting for haplotype ancestry, we found that the European inverted allele in children carries a recessive risk of underweight, validated in an independent Spanish cohort (combined: OR= 2.00, P = 0.001). While the footprints of inversions on SNP data are complex, we show that systematic analyses, such as convergence of different methods and controlling for ancestry, can reveal the contribution of inversions to the ancestral composition of populations and to the heritability of human disease. PMID:25672393

  2. An unusual haplotype structure on human chromosome 8p23 derived from the inversion polymorphism.

    PubMed

    Deng, Libin; Zhang, Yuezheng; Kang, Jian; Liu, Tao; Zhao, Hongbin; Gao, Yang; Li, Chaohua; Pan, Hao; Tang, Xiaoli; Wang, Dunmei; Niu, Tianhua; Yang, Huanming; Zeng, Changqing

    2008-10-01

    Chromosomal inversion is an important type of genomic variations involved in both evolution and disease pathogenesis. Here, we describe the refined genetic structure of a 3.8-Mb inversion polymorphism at chromosome 8p23. Using HapMap data of 1,073 SNPs generated from 209 unrelated samples from CEPH-Utah residents with ancestry from northern and western Europe (CEU); Yoruba in Ibadan, Nigeria (YRI); and Asian (ASN) samples, which were comprised of Han Chinese from Beijing, China (CHB) and Japanese from Tokyo, Japan (JPT)-we successfully deduced the inversion orientations of all their 418 haplotypes. In particular, distinct haplotype subgroups were identified based on principal component analysis (PCA). Such genetic substructures were consistent with clustering patterns based on neighbor-joining tree reconstruction, which revealed a total of four haplotype clades across all samples. Metaphase fluorescence in situ hybridization (FISH) in a subset of 10 HapMap samples verified their inversion orientations predicted by PCA or phylogenetic tree reconstruction. Positioning of the outgroup haplotype within one of YRI clades suggested that Human NCBI Build 36-inverted order is most likely the ancestral orientation. Furthermore, the population differentiation test and the relative extended haplotype homozygosity (REHH) analysis in this region discovered multiple selection signals, also in a population-specific manner. A positive selection signal was detected at XKR6 in the ASN population. These results revealed the correlation of inversion polymorphisms to population-specific genetic structures, and various selection patterns as possible mechanisms for the maintenance of a large chromosomal rearrangement at 8p23 region during evolution. In addition, our study also showed that haplotype-based clustering methods, such as PCA, can be applied in scanning for cryptic inversion polymorphisms at a genome-wide scale.

  3. The Number of Overlapping AID Hotspots in Germline IGHV Genes Is Inversely Correlated with Mutation Frequency in Chronic Lymphocytic Leukemia.

    PubMed

    Yuan, Chaohui; Chu, Charles C; Yan, Xiao-Jie; Bagnara, Davide; Chiorazzi, Nicholas; MacCarthy, Thomas

    2017-01-01

    The targeting of mutations by Activation-Induced Deaminase (AID) is a key step in generating antibody diversity at the Immunoglobulin (Ig) loci but is also implicated in B-cell malignancies such as chronic lymphocytic leukemia (CLL). AID has previously been shown to preferentially deaminate WRC (W = A/T, R = A/G) hotspots. WGCW sites, which contain an overlapping WRC hotspot on both DNA strands, mutate at much higher frequency than single hotspots. Human Ig heavy chain (IGHV) genes differ in terms of WGCW numbers, ranging from 4 for IGHV3-48*03 to as many as 12 in IGHV1-69*01. An absence of V-region mutations in CLL patients ("IGHV unmutated", or U-CLL) is associated with a poorer prognosis compared to "IGHV mutated" (M-CLL) patients. The reasons for this difference are still unclear, but it has been noted that particular IGHV genes associate with U-CLL vs M-CLL. For example, patients with IGHV1-69 clones tend to be U-CLL with a poor prognosis, whereas patients with IGHV3-30 tend to be M-CLL and have a better prognosis. Another distinctive feature of CLL is that ~30% of (mostly poor prognosis) patients can be classified into "stereotyped" subsets, each defined by HCDR3 similarity, suggesting selection, possibly for a self-antigen. We analyzed >1000 IGHV genes from CLL patients and found a highly significant statistical relationship between the number of WGCW hotspots in the germline V-region and the observed mutation frequency in patients. However, paradoxically, this correlation was inverse, with V-regions with more WGCW hotspots being less likely to be mutated, i.e., more likely to be U-CLL. The number of WGCW hotspots in particular, are more strongly correlated with mutation frequency than either non-overlapping (WRC) hotspots or more general models of mutability derived from somatic hypermutation data. Furthermore, this correlation is not observed in sequences from the B cell repertoires of normal individuals and those with autoimmune diseases.

  4. The Number of Overlapping AID Hotspots in Germline IGHV Genes Is Inversely Correlated with Mutation Frequency in Chronic Lymphocytic Leukemia

    PubMed Central

    Yuan, Chaohui; Chu, Charles C.; Yan, Xiao-Jie; Bagnara, Davide; Chiorazzi, Nicholas

    2017-01-01

    The targeting of mutations by Activation-Induced Deaminase (AID) is a key step in generating antibody diversity at the Immunoglobulin (Ig) loci but is also implicated in B-cell malignancies such as chronic lymphocytic leukemia (CLL). AID has previously been shown to preferentially deaminate WRC (W = A/T, R = A/G) hotspots. WGCW sites, which contain an overlapping WRC hotspot on both DNA strands, mutate at much higher frequency than single hotspots. Human Ig heavy chain (IGHV) genes differ in terms of WGCW numbers, ranging from 4 for IGHV3-48*03 to as many as 12 in IGHV1-69*01. An absence of V-region mutations in CLL patients (“IGHV unmutated”, or U-CLL) is associated with a poorer prognosis compared to “IGHV mutated” (M-CLL) patients. The reasons for this difference are still unclear, but it has been noted that particular IGHV genes associate with U-CLL vs M-CLL. For example, patients with IGHV1-69 clones tend to be U-CLL with a poor prognosis, whereas patients with IGHV3-30 tend to be M-CLL and have a better prognosis. Another distinctive feature of CLL is that ~30% of (mostly poor prognosis) patients can be classified into “stereotyped” subsets, each defined by HCDR3 similarity, suggesting selection, possibly for a self-antigen. We analyzed >1000 IGHV genes from CLL patients and found a highly significant statistical relationship between the number of WGCW hotspots in the germline V-region and the observed mutation frequency in patients. However, paradoxically, this correlation was inverse, with V-regions with more WGCW hotspots being less likely to be mutated, i.e., more likely to be U-CLL. The number of WGCW hotspots in particular, are more strongly correlated with mutation frequency than either non-overlapping (WRC) hotspots or more general models of mutability derived from somatic hypermutation data. Furthermore, this correlation is not observed in sequences from the B cell repertoires of normal individuals and those with autoimmune diseases. PMID:28125682

  5. Multi-frequency subspace migration for imaging of perfectly conducting, arc-like cracks in full- and limited-view inverse scattering problems

    NASA Astrophysics Data System (ADS)

    Park, Won-Kwang

    2015-02-01

    Multi-frequency subspace migration imaging techniques are usually adopted for the non-iterative imaging of unknown electromagnetic targets, such as cracks in concrete walls or bridges and anti-personnel mines in the ground, in the inverse scattering problems. It is confirmed that this technique is very fast, effective, robust, and can not only be applied to full- but also to limited-view inverse problems if a suitable number of incidents and corresponding scattered fields are applied and collected. However, in many works, the application of such techniques is heuristic. With the motivation of such heuristic application, this study analyzes the structure of the imaging functional employed in the subspace migration imaging technique in two-dimensional full- and limited-view inverse scattering problems when the unknown targets are arbitrary-shaped, arc-like perfectly conducting cracks located in the two-dimensional homogeneous space. In contrast to the statistical approach based on statistical hypothesis testing, our approach is based on the fact that the subspace migration imaging functional can be expressed by a linear combination of the Bessel functions of integer order of the first kind. This is based on the structure of the Multi-Static Response (MSR) matrix collected in the far-field at nonzero frequency in either Transverse Magnetic (TM) mode (Dirichlet boundary condition) or Transverse Electric (TE) mode (Neumann boundary condition). The investigation of the expression of imaging functionals gives us certain properties of subspace migration and explains why multi-frequency enhances imaging resolution. In particular, we carefully analyze the subspace migration and confirm some properties of imaging when a small number of incident fields are applied. Consequently, we introduce a weighted multi-frequency imaging functional and confirm that it is an improved version of subspace migration in TM mode. Various results of numerical simulations performed on the far-field data affected by large amounts of random noise are similar to the analytical results derived in this study, and they provide a direction for future studies.

  6. Dynamic characterization of viscoelastic porous foams used in vehicles based on an inverse finite element method.

    PubMed

    Finnveden, Svante; Hörlin, Nils-Erik; Barbagallo, Mathias

    2014-04-01

    Viscoelastic properties of porous materials, typical of those used in vehicles for noise insulation and absorption, are estimated from measurements and inverse finite element procedures. The measurements are taken in a near vacuum and cover a broad frequency range: 20 Hz to 1 kHz. The almost cubic test samples were made of 25 mm foam covered by a "heavy layer" of rubber. They were mounted in a vacuum chamber on an aluminum table, which was excited in the vertical and horizontal directions with a shaker. Three kinds of response are measured allowing complete estimates of the viscoelastic moduli for isotropic materials and also providing some information on the degree of material anisotropicity. First, frequency independent properties are estimated, where dissipation is described by constant loss factors. Then, fractional derivative models that capture the variation with frequency of the stiffness and damping are adapted. The measurement setup is essentially two-dimensional and calculations are three-dimensional and for a state of plane strain. The good agreement between measured and calculated response provides some confidence in the presented procedures. If, however, the material model cannot fit the measurements well, the inverse procedure yields a certain degree of arbitrariness to the parameter estimation.

  7. Structural-change localization and monitoring through a perturbation-based inverse problem.

    PubMed

    Roux, Philippe; Guéguen, Philippe; Baillet, Laurent; Hamze, Alaa

    2014-11-01

    Structural-change detection and characterization, or structural-health monitoring, is generally based on modal analysis, for detection, localization, and quantification of changes in structure. Classical methods combine both variations in frequencies and mode shapes, which require accurate and spatially distributed measurements. In this study, the detection and localization of a local perturbation are assessed by analysis of frequency changes (in the fundamental mode and overtones) that are combined with a perturbation-based linear inverse method and a deconvolution process. This perturbation method is applied first to a bending beam with the change considered as a local perturbation of the Young's modulus, using a one-dimensional finite-element model for modal analysis. Localization is successful, even for extended and multiple changes. In a second step, the method is numerically tested under ambient-noise vibration from the beam support with local changes that are shifted step by step along the beam. The frequency values are revealed using the random decrement technique that is applied to the time-evolving vibrations recorded by one sensor at the free extremity of the beam. Finally, the inversion method is experimentally demonstrated at the laboratory scale with data recorded at the free end of a Plexiglas beam attached to a metallic support.

  8. Non-ambiguous recovery of Biot poroelastic parameters of cellular panels using ultrasonicwaves

    NASA Astrophysics Data System (ADS)

    Ogam, Erick; Fellah, Z. E. A.; Sebaa, Naima; Groby, J.-P.

    2011-03-01

    The inverse problem of the recovery of the poroelastic parameters of open-cell soft plastic foam panels is solved by employing transmitted ultrasonic waves (USW) and the Biot-Johnson-Koplik-Champoux-Allard (BJKCA) model. It is shown by constructing the objective functional given by the total square of the difference between predictions from the BJKCA interaction model and experimental data obtained with transmitted USW that the inverse problem is ill-posed, since the functional exhibits several local minima and maxima. In order to solve this problem, which is beyond the capability of most off-the-shelf iterative nonlinear least squares optimization algorithms (such as the Levenberg Marquadt or Nelder-Mead simplex methods), simple strategies are developed. The recovered acoustic parameters are compared with those obtained using simpler interaction models and a method employing asymptotic phase velocity of the transmitted USW. The retrieved elastic moduli are validated by solving an inverse vibration spectroscopy problem with data obtained from beam-like specimens cut from the panels using an equivalent solid elastodynamic model as estimator. The phase velocities are reconstructed using computed, measured resonance frequencies and a time-frequency decomposition of transient waves induced in the beam specimen. These confirm that the elastic parameters recovered using vibration are valid over the frequency range ofstudy.

  9. A Method to Compute the Force Signature of a Body Impacting on a Linear Elastic Structure Using Fourier Analysis

    DTIC Science & Technology

    1982-09-17

    FK * 1PK (2) The convolution of two transforms in time domain is the inverse transform of the product in frequency domain. Thus Rp(s) - Fgc() Ipg(*) (3...its inverse transform by: R,(r)- R,(a.)e’’ do. (5)2w In order to nuke use f a very accurate numerical method to ompute Fourier "ke and coil...taorm. When the inverse transform it tken by using Eq. (15), the cosine transform, because it converges faster than the sine transform refu-ft the

  10. An iterative solver for the 3D Helmholtz equation

    NASA Astrophysics Data System (ADS)

    Belonosov, Mikhail; Dmitriev, Maxim; Kostin, Victor; Neklyudov, Dmitry; Tcheverda, Vladimir

    2017-09-01

    We develop a frequency-domain iterative solver for numerical simulation of acoustic waves in 3D heterogeneous media. It is based on the application of a unique preconditioner to the Helmholtz equation that ensures convergence for Krylov subspace iteration methods. Effective inversion of the preconditioner involves the Fast Fourier Transform (FFT) and numerical solution of a series of boundary value problems for ordinary differential equations. Matrix-by-vector multiplication for iterative inversion of the preconditioned matrix involves inversion of the preconditioner and pointwise multiplication of grid functions. Our solver has been verified by benchmarking against exact solutions and a time-domain solver.

  11. An infrared-visible image fusion scheme based on NSCT and compressed sensing

    NASA Astrophysics Data System (ADS)

    Zhang, Qiong; Maldague, Xavier

    2015-05-01

    Image fusion, as a research hot point nowadays in the field of infrared computer vision, has been developed utilizing different varieties of methods. Traditional image fusion algorithms are inclined to bring problems, such as data storage shortage and computational complexity increase, etc. Compressed sensing (CS) uses sparse sampling without knowing the priori knowledge and greatly reconstructs the image, which reduces the cost and complexity of image processing. In this paper, an advanced compressed sensing image fusion algorithm based on non-subsampled contourlet transform (NSCT) is proposed. NSCT provides better sparsity than the wavelet transform in image representation. Throughout the NSCT decomposition, the low-frequency and high-frequency coefficients can be obtained respectively. For the fusion processing of low-frequency coefficients of infrared and visible images , the adaptive regional energy weighting rule is utilized. Thus only the high-frequency coefficients are specially measured. Here we use sparse representation and random projection to obtain the required values of high-frequency coefficients, afterwards, the coefficients of each image block can be fused via the absolute maximum selection rule and/or the regional standard deviation rule. In the reconstruction of the compressive sampling results, a gradient-based iterative algorithm and the total variation (TV) method are employed to recover the high-frequency coefficients. Eventually, the fused image is recovered by inverse NSCT. Both the visual effects and the numerical computation results after experiments indicate that the presented approach achieves much higher quality of image fusion, accelerates the calculations, enhances various targets and extracts more useful information.

  12. Recognition memory across the lifespan: the impact of word frequency and study-test interval on estimates of familiarity and recollection

    PubMed Central

    Meier, Beat; Rey-Mermet, Alodie; Rothen, Nicolas; Graf, Peter

    2013-01-01

    The goal of this study was to investigate recognition memory performance across the lifespan and to determine how estimates of recollection and familiarity contribute to performance. In each of three experiments, participants from five groups from 14 up to 85 years of age (children, young adults, middle-aged adults, young-old adults, and old-old adults) were presented with high- and low-frequency words in a study phase and were tested immediately afterwards and/or after a one day retention interval. The results showed that word frequency and retention interval affected recognition memory performance as well as estimates of recollection and familiarity. Across the lifespan, the trajectory of recognition memory followed an inverse u-shape function that was neither affected by word frequency nor by retention interval. The trajectory of estimates of recollection also followed an inverse u-shape function, and was especially pronounced for low-frequency words. In contrast, estimates of familiarity did not differ across the lifespan. The results indicate that age differences in recognition memory are mainly due to differences in processes related to recollection while the contribution of familiarity-based processes seems to be age-invariant. PMID:24198796

  13. Direct vibro-elastography FEM inversion in Cartesian and cylindrical coordinate systems without the local homogeneity assumption

    NASA Astrophysics Data System (ADS)

    Honarvar, M.; Lobo, J.; Mohareri, O.; Salcudean, S. E.; Rohling, R.

    2015-05-01

    To produce images of tissue elasticity, the vibro-elastography technique involves applying a steady-state multi-frequency vibration to tissue, estimating displacements from ultrasound echo data, and using the estimated displacements in an inverse elasticity problem with the shear modulus spatial distribution as the unknown. In order to fully solve the inverse problem, all three displacement components are required. However, using ultrasound, the axial component of the displacement is measured much more accurately than the other directions. Therefore, simplifying assumptions must be used in this case. Usually, the equations of motion are transformed into a Helmholtz equation by assuming tissue incompressibility and local homogeneity. The local homogeneity assumption causes significant imaging artifacts in areas of varying elasticity. In this paper, we remove the local homogeneity assumption. In particular we introduce a new finite element based direct inversion technique in which only the coupling terms in the equation of motion are ignored, so it can be used with only one component of the displacement. Both Cartesian and cylindrical coordinate systems are considered. The use of multi-frequency excitation also allows us to obtain multiple measurements and reduce artifacts in areas where the displacement of one frequency is close to zero. The proposed method was tested in simulations and experiments against a conventional approach in which the local homogeneity is used. The results show significant improvements in elasticity imaging with the new method compared to previous methods that assumes local homogeneity. For example in simulations, the contrast to noise ratio (CNR) for the region with spherical inclusion increases from an average value of 1.5-17 after using the proposed method instead of the local inversion with homogeneity assumption, and similarly in the prostate phantom experiment, the CNR improved from an average value of 1.6 to about 20.

  14. Contrast source inversion (CSI) method to cross-hole radio-imaging (RIM) data - Part 2: A complex synthetic example and a case study

    NASA Astrophysics Data System (ADS)

    Li, Yongxing; Smith, Richard S.

    2018-03-01

    We present two examples of using the contrast source inversion (CSI) method to invert synthetic radio-imaging (RIM) data and field data. The synthetic model has two isolated conductors (one perfect conductor and one moderate conductor) embedded in a layered background. After inversion, we can identify the two conductors on the inverted image. The shape of the perfect conductor is better resolved than the shape of the moderate conductor. The inverted conductivity values of the two conductors are approximately the same, which demonstrates that the conductivity values cannot be correctly interpreted from the CSI results. The boundaries and the tilts of the upper and the lower conductive layers on the background can also be inferred from the results, but the centre parts of conductive layers in the inversion results are more conductive than the parts close to the boreholes. We used the straight-ray tomographic imaging method and the CSI method to invert the RIM field data collected using the FARA system between two boreholes in a mining area in Sudbury, Canada. The RIM data include the amplitude and the phase data collected using three frequencies: 312.5 kHz, 625 kHz and 1250 kHz. The data close to the ground surface have high amplitude values and complicated phase fluctuations, which are inferred to be contaminated by the reflected or refracted electromagnetic (EM) fields from the ground surface, and are removed for all frequencies. Higher-frequency EM waves attenuate more quickly in the subsurface environment, and the locations where the measurements are dominated by noise are also removed. When the data are interpreted with the straight-ray method, the images differ substantially for different frequencies. In addition, there are some unexpected features in the images, which are difficult to interpret. Compared with the straight-ray imaging results, the inversion results with the CSI method are more consistent for different frequencies. On the basis of what we learnt from the synthetic study, we interpret that there is one resistive layer across the middle of the borehole plane and two more conductive areas above and below this layer. Though there are some limitations in the study, such as large transmitter steps and the precise amplitudes and dipole moments being unknown, we conclude that the CSI method provides more interpretable images compared with the straight-ray method.

  15. A New Paradigm for Satellite Retrieval of Hydrologic Variables: The CDRD Methodology

    NASA Astrophysics Data System (ADS)

    Smith, E. A.; Mugnai, A.; Tripoli, G. J.

    2009-09-01

    Historically, retrieval of thermodynamically active geophysical variables in the atmosphere (e.g., temperature, moisture, precipitation) involved some time of inversion scheme - embedded within the retrieval algorithm - to transform radiometric observations (a vector) to the desired geophysical parameter(s) (either a scalar or a vector). Inversion is fundamentally a mathematical operation involving some type of integral-differential radiative transfer equation - often resisting a straightforward algebraic solution - in which the integral side of the equation (typically the right-hand side) contains the desired geophysical vector, while the left-hand side contains the radiative measurement vector often free of operators. Inversion was considered more desirable than forward modeling because the forward model solution had to be selected from a generally unmanageable set of parameter-observation relationships. However, in the classical inversion problem for retrieval of temperature using multiple radiative frequencies along the wing of an absorption band (or line) of a well-mixed radiatively active gas, in either the infrared or microwave spectrums, the inversion equation to be solved consists of a Fredholm integral equation of the 2nd kind - a specific type of transform problem in which there are an infinite number of solutions. This meant that special treatment of the transform process was required in order to obtain a single solution. Inversion had become the method of choice for retrieval in the 1950s because it appealed to the use of mathematical elegance, and because the numerical approaches used to solve the problems (typically some type of relaxation or perturbation scheme) were computationally fast in an age when computers speeds were slow. Like many solution schemes, inversion has lingered on regardless of the fact that computer speeds have increased many orders of magnitude and forward modeling itself has become far more elegant in combination with Bayesian averaging procedures given that the a priori probabilities of occurrence in the true environment of the parameter(s) in question can be approximated (or are actually known). In this presentation, the theory of the more modern retrieval approach using a combination of cloud, radiation and other specialized forward models in conjunction with Bayesian weighted averaging will be reviewed in light of a brief history of inversion. The application of the theory will be cast in the framework of what we call the Cloud-Dynamics-Radiation-Database (CDRD) methodology - which we now use for the retrieval of precipitation from spaceborne passive microwave radiometers. In a companion presentation, we will specifically describe the CDRD methodology and present results for its application within the Mediterranean basin.

  16. Inverse Doppler Effects in Broadband Acoustic Metamaterials

    PubMed Central

    Zhai, S. L.; Zhao, X. P.; Liu, S.; Shen, F. L.; Li, L. L.; Luo, C. R.

    2016-01-01

    The Doppler effect refers to the change in frequency of a wave source as a consequence of the relative motion between the source and an observer. Veselago theoretically predicted that materials with negative refractions can induce inverse Doppler effects. With the development of metamaterials, inverse Doppler effects have been extensively investigated. However, the ideal material parameters prescribed by these metamaterial design approaches are complex and also challenging to obtain experimentally. Here, we demonstrated a method of designing and experimentally characterising arbitrary broadband acoustic metamaterials. These omni-directional, double-negative, acoustic metamaterials are constructed with ‘flute-like’ acoustic meta-cluster sets with seven double meta-molecules; these metamaterials also overcome the limitations of broadband negative bulk modulus and mass density to provide a region of negative refraction and inverse Doppler effects. It was also shown that inverse Doppler effects can be detected in a flute, which has been popular for thousands of years in Asia and Europe. PMID:27578317

  17. Inverse Doppler Effects in Broadband Acoustic Metamaterials

    NASA Astrophysics Data System (ADS)

    Zhai, S. L.; Zhao, X. P.; Liu, S.; Shen, F. L.; Li, L. L.; Luo, C. R.

    2016-08-01

    The Doppler effect refers to the change in frequency of a wave source as a consequence of the relative motion between the source and an observer. Veselago theoretically predicted that materials with negative refractions can induce inverse Doppler effects. With the development of metamaterials, inverse Doppler effects have been extensively investigated. However, the ideal material parameters prescribed by these metamaterial design approaches are complex and also challenging to obtain experimentally. Here, we demonstrated a method of designing and experimentally characterising arbitrary broadband acoustic metamaterials. These omni-directional, double-negative, acoustic metamaterials are constructed with ‘flute-like’ acoustic meta-cluster sets with seven double meta-molecules; these metamaterials also overcome the limitations of broadband negative bulk modulus and mass density to provide a region of negative refraction and inverse Doppler effects. It was also shown that inverse Doppler effects can be detected in a flute, which has been popular for thousands of years in Asia and Europe.

  18. Contrast sensitivity test and conventional and high frequency audiometry: information beyond that required to prescribe lenses and headsets

    NASA Astrophysics Data System (ADS)

    Comastri, S. A.; Martin, G.; Simon, J. M.; Angarano, C.; Dominguez, S.; Luzzi, F.; Lanusse, M.; Ranieri, M. V.; Boccio, C. M.

    2008-04-01

    In Optometry and in Audiology, the routine tests to prescribe correction lenses and headsets are respectively the visual acuity test (the first chart with letters was developed by Snellen in 1862) and conventional pure tone audiometry (the first audiometer with electrical current was devised by Hartmann in 1878). At present there are psychophysical non invasive tests that, besides evaluating visual and auditory performance globally and even in cases catalogued as normal according to routine tests, supply early information regarding diseases such as diabetes, hypertension, renal failure, cardiovascular problems, etc. Concerning Optometry, one of these tests is the achromatic luminance contrast sensitivity test (introduced by Schade in 1956). Concerning Audiology, one of these tests is high frequency pure tone audiometry (introduced a few decades ago) which yields information relative to pathologies affecting the basal cochlea and complements data resulting from conventional audiometry. These utilities of the contrast sensitivity test and of pure tone audiometry derive from the facts that Fourier components constitute the basis to synthesize stimuli present at the entrance of the visual and auditory systems; that these systems responses depend on frequencies and that the patient's psychophysical state affects frequency processing. The frequency of interest in the former test is the effective spatial frequency (inverse of the angle subtended at the eye by a cycle of a sinusoidal grating and measured in cycles/degree) and, in the latter, the temporal frequency (measured in cycles/sec). Both tests have similar duration and consist in determining the patient's threshold (corresponding to the inverse multiplicative of the contrast or to the inverse additive of the sound intensity level) for each harmonic stimulus present at the system entrance (sinusoidal grating or pure tone sound). In this article the frequencies, standard normality curves and abnormal threshold shifts inherent to the contrast sensitivity test (which for simplicity could be termed "visionmetry") and to pure tone audiometry (also termed auditory sensitivity test) are analyzed with the purpose of contributing to divulge their ability to supply early information associated to pathologies not solely related to the visual and auditory systems respectively.

  19. A 3D inversion for all-space magnetotelluric data with static shift correction

    NASA Astrophysics Data System (ADS)

    Zhang, Kun

    2017-04-01

    Base on the previous studies on the static shift correction and 3D inversion algorithms, we improve the NLCG 3D inversion method and propose a new static shift correction method which work in the inversion. The static shift correction method is based on the 3D theory and real data. The static shift can be detected by the quantitative analysis of apparent parameters (apparent resistivity and impedance phase) of MT in high frequency range, and completed correction with inversion. The method is an automatic processing technology of computer with 0 cost, and avoids the additional field work and indoor processing with good results. The 3D inversion algorithm is improved (Zhang et al., 2013) base on the NLCG method of Newman & Alumbaugh (2000) and Rodi & Mackie (2001). For the algorithm, we added the parallel structure, improved the computational efficiency, reduced the memory of computer and added the topographic and marine factors. So the 3D inversion could work in general PC with high efficiency and accuracy. And all the MT data of surface stations, seabed stations and underground stations can be used in the inversion algorithm.

  20. Long-Term Fragility of Y Chromosomes Is Dominated by Short-Term Resolution of Sexual Antagonism

    PubMed Central

    Blackmon, Heath; Brandvain, Yaniv

    2017-01-01

    The evolution of heteromorphic sex chromosomes has fascinated biologists, inspiring theoretical models, experimental studies, and studies of genome structure. This work has produced a clear model, in which heteromorphic sex chromosomes result from repeated fixations of inversions (or other recombination suppression mechanisms) that tether sexually antagonistic alleles to sex-determining regions, followed by the degeneration of these regions induced by the lack of sex chromosome recombination in the heterogametic sex. However, current models do not predict if inversions are expected to preferentially accumulate on one sex-chromosome or another, and do not address if inversions can accumulate even when they cause difficulties in pairing between heteromorphic chromosomes in the heterogametic sex increasing aneuploidy or meiotic arrest. To address these questions, we developed a population genetic model in which the sex chromosome aneuploidy rate is elevated when males carry an inversion on either the X or Y chromosome. We show that inversions fix more easily when male-beneficial alleles are dominant, and that inversions on the Y chromosome fix with lower selection coefficients than comparable X chromosome inversions. We further show that sex-chromosome inversions can often invade and fix despite causing a substantial increase in the risk of aneuploidy. As sexual antagonism can lead to the fixation of inversions that increase sex chromosomes aneuploidy (which underlies genetic diseases including Klinefelter and Turner syndrome in humans) selection could subsequently favor diverse mechanisms to reduce aneuploidy—including alternative meiotic mechanisms, translocations to, and fusions with, the sex chromosomes, and sex chromosome turnover. PMID:29021279

  1. Does Face Inversion Change Spatial Frequency Tuning?

    ERIC Educational Resources Information Center

    Willenbockel, Verena; Fiset, Daniel; Chauvin, Alan; Blais, Caroline; Arguin, Martin; Tanaka, James W.; Bub, Daniel N.; Gosselin, Frederic

    2010-01-01

    The authors examined spatial frequency (SF) tuning of upright and inverted face identification using an SF variant of the Bubbles technique (F. Gosselin & P. G. Schyns, 2001). In Experiment 1, they validated the SF Bubbles technique in a plaid detection task. In Experiments 2a-c, the SFs used for identifying upright and inverted inner facial…

  2. Inversion of high frequency surface waves with fundamental and higher modes

    USGS Publications Warehouse

    Xia, J.; Miller, R.D.; Park, C.B.; Tian, G.

    2003-01-01

    The phase velocity of Rayleigh-waves of a layered earth model is a function of frequency and four groups of earth parameters: compressional (P)-wave velocity, shear (S)-wave velocity, density, and thickness of layers. For the fundamental mode of Rayleigh waves, analysis of the Jacobian matrix for high frequencies (2-40 Hz) provides a measure of dispersion curve sensitivity to earth model parameters. S-wave velocities are the dominant influence of the four earth model parameters. This thesis is true for higher modes of high frequency Rayleigh waves as well. Our numerical modeling by analysis of the Jacobian matrix supports at least two quite exciting higher mode properties. First, for fundamental and higher mode Rayleigh wave data with the same wavelength, higher modes can "see" deeper than the fundamental mode. Second, higher mode data can increase the resolution of the inverted S-wave velocities. Real world examples show that the inversion process can be stabilized and resolution of the S-wave velocity model can be improved when simultaneously inverting the fundamental and higher mode data. ?? 2002 Elsevier Science B.V. All rights reserved.

  3. Dual Fractal Dimension and Long-Range Correlation of Chinese Stock Prices

    NASA Astrophysics Data System (ADS)

    Chen, Chaoshi; Wang, Lei

    2012-03-01

    The recently developed modified inverse random midpoint displacement (mIRMD) and conventional detrended fluctuation analysis (DFA) algorithms are used to analyze the tick-by-tick high-frequency time series of Chinese A-share stock prices and indexes. A dual-fractal structure with a crossover at about 10 min is observed. The majority of the selected time series show visible persistence within this time threshold, but approach a random walk on a longer time scale. The phenomenon is found to be industry-dependent, i.e., the crossover is much more prominent for stocks belonging to cyclical industries than for those belonging to noncyclical (defensive) industries. We have also shown that the sign series show a similar dual-fractal structure, while like generally found, the magnitude series show a much longer time persistence.

  4. Ground mapping resolution accuracy of a scanning radiometer from a geostationary satellite.

    PubMed

    Stremler, F G; Khalil, M A; Parent, R J

    1977-06-01

    Measures of the spatial and spatial rate (frequency) mapping of scanned visual imagery from an earth reference system to a spin-scan geostationary satellite are examined. Mapping distortions and coordinate inversions to correct for these distortions are formulated in terms of geometric transformations between earth and satellite frames of reference. Probabilistic methods are used to develop relations for obtainable mapping resolution when coordinate inversions are employed.

  5. Surface Wave Mode Conversion due to Lateral Heterogeneity and its Impact on Waveform Inversions

    NASA Astrophysics Data System (ADS)

    Datta, A.; Priestley, K. F.; Chapman, C. H.; Roecker, S. W.

    2016-12-01

    Surface wave tomography based on great circle ray theory has certain limitations which become increasingly significant with increasing frequency. One such limitation is the assumption of different surface wave modes propagating independently from source to receiver, valid only in case of smoothly varying media. In the real Earth, strong lateral gradients can cause significant interconversion among modes, thus potentially wreaking havoc with ray theory based tomographic inversions that make use of multimode information. The issue of mode coupling (with either normal modes or surface wave modes) for accurate modelling and inversion of body wave data has received significant attention in the seismological literature, but its impact on inversion of surface waveforms themselves remains much less understood.We present an empirical study with synthetic data, to investigate this problem with a two-fold approach. In the first part, 2D forward modelling using a new finite difference method that allows modelling a single mode at a time, is used to build a general picture of energy transfer among modes as a function of size, strength and sharpness of lateral heterogeneities. In the second part, we use the example of a multimode waveform inversion technique based on the Cara and Leveque (1987) approach of secondary observables, to invert our synthetic data and assess how mode conversion can affect the process of imaging the Earth. We pay special attention to ensuring that any biases or artefacts in the resulting inversions can be unambiguously attributed to mode conversion effects. This study helps pave the way towards the next generation of (non-numerical) surface wave tomography techniques geared to exploit higher frequencies and mode numbers than are typically used today.

  6. Selective fatigue of fast motor units after electrically elicited muscle contractions.

    PubMed

    Hamada, Taku; Kimura, Tetsuya; Moritani, Toshio

    2004-10-01

    The aim of the present study was to elucidate the electrophysiological manifestations of selective fast motor unit (MU) activation by electrical stimulation (ES) of knee extensor muscles. In six male subjects, test contraction measurement at 40% maximal voluntary contraction (MVC) was performed before and at every 5 min (5, 10, 15 and 20 min) during 20-min low intensity intermittent exercise of either ES or voluntary contractions (VC) at 10% MVC (5-s isometric contraction and 5-s rest cycles). Both isolated intramuscular MU spikes obtained from three sets of bipolar fine-wire electrodes and surface electromyogram (EMG) were simultaneously recorded and were analyzed by means of a computer-aided intramuscular spike amplitude-frequency analysis and frequency power spectral analysis, respectively. Results indicated that mean MU spike amplitude, particularly those MUs with relatively large amplitude, was significantly reduced while those MUs with small spike amplitude increased their firing rate during the 40% MVC test contraction after the ES. This was accompanied by the increased amplitude of surface EMG (rmsEMG). However, no such significant changes in the intramuscular and surface EMGs were observed after VC. These findings indicated differential MU activation patterns in terms of MU recruitment and rate coding characteristics during ES and VC, respectively. Our data strongly suggest the possibility of "an inverse size principle" of MU recruitment during ES.

  7. 11.2 YIP Human In the Loop Statistical RelationalLearners

    DTIC Science & Technology

    2017-10-23

    learning formalisms including inverse reinforcement learning [4] and statistical relational learning [7, 5, 8]. We have also applied our algorithms in...one introduced for label preferences. 4 Figure 2: Active Advice Seeking for Inverse Reinforcement Learning. active advice seeking is in selecting the...learning tasks. 1.2.1 Sequential Decision-Making Our previous work on advice for inverse reinforcement learning (IRL) defined advice as action

  8. Signal frequency distribution and natural-time analyses from acoustic emission monitoring of an arched structure in the Castle of Racconigi

    NASA Astrophysics Data System (ADS)

    Niccolini, Gianni; Manuello, Amedeo; Marchis, Elena; Carpinteri, Alberto

    2017-07-01

    The stability of an arch as a structural element in the thermal bath of King Charles Albert (Carlo Alberto) in the Royal Castle of Racconigi (on the UNESCO World Heritage List since 1997) was assessed by the acoustic emission (AE) monitoring technique with application of classical inversion methods to recorded AE data. First, damage source location by means of triangulation techniques and signal frequency analysis were carried out. Then, the recently introduced method of natural-time analysis was preliminarily applied to the AE time series in order to reveal a possible entrance point to a critical state of the monitored structural element. Finally, possible influence of the local seismic and microseismic activity on the stability of the monitored structure was investigated. The criterion for selecting relevant earthquakes was based on the estimation of the size of earthquake preparation zones. The presented results suggest the use of the AE technique as a tool for detecting both ongoing structural damage processes and microseismic activity during preparation stages of seismic events.

  9. Decision making with uncertain reinforcement in children with attention deficit/hyperactivity disorder (ADHD).

    PubMed

    Drechsler, Renate; Rizzo, Patrizia; Steinhausen, Hans-Christoph

    2010-01-01

    Reward-related processes are impaired in children with ADHD. Whether these deficits can be ascribed to an aversion to delay or to an altered responsiveness to magnitude, frequency, valence, or the probability of rewards still needs to be explored. In the present study, children with ADHD and normal controls aged 7 to 10 years performed a simple probabilistic discounting task. They had to choose between alternatives where the magnitude of rewards was inversely related to the probability of outcomes. As a result, children with ADHD opted more frequently for less likely but larger rewards than normal controls. Shifts of the response category after positive or negative feedback, however, occurred as often in children with ADHD as in control children. In children with ADHD, the frequency of risky choices was correlated with neuropsychological measures of response time variability but unrelated to measures of inhibitory control. It is concluded that the tendency to select less likely but larger rewards possibly represents a separate facet of dysfunctional reward processing, independent of delay aversion or altered responsiveness to feedback.

  10. Scale-specific effects: A report on multiscale analysis of acupunctured EEG in entropy and power

    NASA Astrophysics Data System (ADS)

    Song, Zhenxi; Deng, Bin; Wei, Xile; Cai, Lihui; Yu, Haitao; Wang, Jiang; Wang, Ruofan; Chen, Yingyuan

    2018-02-01

    Investigating acupuncture effects contributes to improving clinical application and understanding neuronal dynamics under external stimulation. In this report, we recorded electroencephalography (EEG) signals evoked by acupuncture at ST36 acupoint with three stimulus frequencies of 50, 100 and 200 times per minutes, and selected non-acupuncture EEGs as the control group. Multiscale analyses were introduced to investigate the possible acupuncture effects on complexity and power in multiscale level. Using multiscale weighted-permutation entropy, we found the significant effects on increased complexity degree in EEG signals induced by acupuncture. The comparison of three stimulation manipulations showed that 100 times/min generated most obvious effects, and affected most cortical regions. By estimating average power spectral density, we found decreased power induced by acupuncture. The joint distribution of entropy and power indicated an inverse correlation, and this relationship was weakened by acupuncture effects, especially under the manipulation of 100 times/min frequency. Above findings are more evident and stable in large scales than small scales, which suggests that multiscale analysis allows evaluating significant effects in specific scale and enables to probe the inherent characteristics underlying physiological signals.

  11. An accurate surface topography restoration algorithm for white light interferometry

    NASA Astrophysics Data System (ADS)

    Yuan, He; Zhang, Xiangchao; Xu, Min

    2017-10-01

    As an important measuring technique, white light interferometry can realize fast and non-contact measurement, thus it is now widely used in the field of ultra-precision engineering. However, the traditional recovery algorithms of surface topographies have flaws and limits. In this paper, we propose a new algorithm to solve these problems. It is a combination of Fourier transform and improved polynomial fitting method. Because the white light interference signal is usually expressed as a cosine signal whose amplitude is modulated by a Gaussian function, its fringe visibility is not constant and varies with different scanning positions. The interference signal is processed first by Fourier transform, then the positive frequency part is selected and moved back to the center of the amplitude-frequency curve. In order to restore the surface morphology, a polynomial fitting method is used to fit the amplitude curve after inverse Fourier transform and obtain the corresponding topography information. The new method is then compared to the traditional algorithms. It is proved that the aforementioned drawbacks can be effectively overcome. The relative error is less than 0.8%.

  12. Magnetoresistance effect of heat generation in a single-molecular spin-valve

    NASA Astrophysics Data System (ADS)

    Jiang, Feng; Yan, Yonghong; Wang, Shikuan; Yan, Yijing

    2016-02-01

    Based on non-equilibrium Green's functions' theory and small polaron transformation's technology, we study the heat generation by current through a single-molecular spin-valve. Numerical results indicate that the variation of spin polarization degree can change heat generation effectively, the spin-valve effect happens not only in electrical current but also in heat generation when Coulomb repulsion in quantum dot is smaller than phonon frequency and interestingly, when Coulomb repulsion is larger than phonon frequency, the inverse spin-valve effect appears by sweeping gate voltage and is enlarged with bias increasing. The inverse spin-valve effect will induce the unique heat magnetoresistance effect, which can be modulated from heat-resistance to heat-gain by gate voltage easily.

  13. Genetic algorithms and their use in Geophysical Problems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Parker, Paul B.

    1999-04-01

    Genetic algorithms (GAs), global optimization methods that mimic Darwinian evolution are well suited to the nonlinear inverse problems of geophysics. A standard genetic algorithm selects the best or ''fittest'' models from a ''population'' and then applies operators such as crossover and mutation in order to combine the most successful characteristics of each model and produce fitter models. More sophisticated operators have been developed, but the standard GA usually provides a robust and efficient search. Although the choice of parameter settings such as crossover and mutation rate may depend largely on the type of problem being solved, numerous results show thatmore » certain parameter settings produce optimal performance for a wide range of problems and difficulties. In particular, a low (about half of the inverse of the population size) mutation rate is crucial for optimal results, but the choice of crossover method and rate do not seem to affect performance appreciably. Optimal efficiency is usually achieved with smaller (< 50) populations. Lastly, tournament selection appears to be the best choice of selection methods due to its simplicity and its autoscaling properties. However, if a proportional selection method is used such as roulette wheel selection, fitness scaling is a necessity, and a high scaling factor (> 2.0) should be used for the best performance. Three case studies are presented in which genetic algorithms are used to invert for crustal parameters. The first is an inversion for basement depth at Yucca mountain using gravity data, the second an inversion for velocity structure in the crust of the south island of New Zealand using receiver functions derived from teleseismic events, and the third is a similar receiver function inversion for crustal velocities beneath the Mendocino Triple Junction region of Northern California. The inversions demonstrate that genetic algorithms are effective in solving problems with reasonably large numbers of free parameters and with computationally expensive objective function calculations. More sophisticated techniques are presented for special problems. Niching and island model algorithms are introduced as methods to find multiple, distinct solutions to the nonunique problems that are typically seen in geophysics. Finally, hybrid algorithms are investigated as a way to improve the efficiency of the standard genetic algorithm.« less

  14. Genetic algorithms and their use in geophysical problems

    NASA Astrophysics Data System (ADS)

    Parker, Paul Bradley

    Genetic algorithms (GAs), global optimization methods that mimic Darwinian evolution are well suited to the nonlinear inverse problems of geophysics. A standard genetic algorithm selects the best or "fittest" models from a "population" and then applies operators such as crossover and mutation in order to combine the most successful characteristics of each model and produce fitter models. More sophisticated operators have been developed, but the standard GA usually provides a robust and efficient search. Although the choice of parameter settings such as crossover and mutation rate may depend largely on the type of problem being solved, numerous results show that certain parameter settings produce optimal performance for a wide range of problems and difficulties. In particular, a low (about half of the inverse of the population size) mutation rate is crucial for optimal results, but the choice of crossover method and rate do not seem to affect performance appreciably. Also, optimal efficiency is usually achieved with smaller (<50) populations. Lastly, tournament selection appears to be the best choice of selection methods due to its simplicity and its autoscaling properties. However, if a proportional selection method is used such as roulette wheel selection, fitness scaling is a necessity, and a high scaling factor (>2.0) should be used for the best performance. Three case studies are presented in which genetic algorithms are used to invert for crustal parameters. The first is an inversion for basement depth at Yucca mountain using gravity data, the second an inversion for velocity structure in the crust of the south island of New Zealand using receiver functions derived from teleseismic events, and the third is a similar receiver function inversion for crustal velocities beneath the Mendocino Triple Junction region of Northern California. The inversions demonstrate that genetic algorithms are effective in solving problems with reasonably large numbers of free parameters and with computationally expensive objective function calculations. More sophisticated techniques are presented for special problems. Niching and island model algorithms are introduced as methods to find multiple, distinct solutions to the nonunique problems that are typically seen in geophysics. Finally, hybrid algorithms are investigated as a way to improve the efficiency of the standard genetic algorithm.

  15. Steep radio spectra in high-redshift radio galaxies

    NASA Technical Reports Server (NTRS)

    Krolik, Julian H.; Chen, Wan

    1991-01-01

    The generic spectrum of an optically thin synchrotron source steepens by 0.5 in spectral index from low frequencies to high whenever the source lifetime is greater than the energy-loss timescale for at least some of the radiating electrons. Three effects tend to decrease the frequency nu(b) of this spectral bend as the source redshift increases: (1) for fixed bend frequency nu* in the rest frame, nu(b) = nu*/(1 + z); (2) losses due to inverse Compton scattering the microwave background rise with redshift as (1 + z) exp 4, so that, for fixed residence time in the radiating region, the energy of the lowest energy electron that can cool falls rapidly with increasing redshift; and (3) if the magnetic field is proportional to the equipartition field and the emitting volume is fixed or slowly varying, flux-limited samples induce a selection effect favoring low nu* at high z because higher redshift sources require higher emissivity to be included in the sample, and hence have stronger implied fields and more rapid synchrotron losses. A combination of these effects may explain the trend observed in the 3CR sample for higher redshift radio galaxies to have steeper spectra, and the successful use of ultrasteep spectrum surveys to locate high-redshift galaxies.

  16. Inversion technique for IR heterodyne sounding of stratospheric constituents from space platforms

    NASA Technical Reports Server (NTRS)

    Abbas, M. M.; Shapiro, G. L.; Alvarez, J. M.

    1981-01-01

    The techniques which have been employed for inversion of IR heterodyne measurements for remote sounding of stratospheric trace constituents usually rely on either geometric effects based on limb-scan observations (i.e., onion peel techniques) or spectral effects by using weighting functions corresponding to different frequencies of an IR spectral line. An experimental approach and inversion technique are discussed which optimize the retrieval of concentration profiles by combining the geometric and the spectral effects in an IR heterodyne receiver. The results of inversions of some synthetic CIO spectral lines corresponding to solar occultation limb scans of the stratosphere are presented, indicating considerable improvement in the accuracy of the retrieved profiles. The effects of noise on the accuracy of retrievals are discussed for realistic situations.

  17. Inversion technique for IR heterodyne sounding of stratospheric constituents from space platforms.

    PubMed

    Abbas, M M; Shapiro, G L; Alvarez, J M

    1981-11-01

    The techniques which have been employed for inversion of IR heterodyne measurements for remote sounding of stratospheric trace constituents usually rely on either geometric effects based on limb-scan observations (i.e., onion peel techniques) or spectral effects by using weighting functions corresponding to different frequencies of an IR spectral line. An experimental approach and inversion technique are discussed which optimize the retrieval of concentration profiles by combining the geometric and the spectral effects in an IR heterodyne receiver. The results of inversions of some synthetic ClO spectral lines corresponding to solar occultation limb scans of the stratosphere are presented, indicating considerable improvement in the accuracy of the retrieved profiles. The effects of noise on the accuracy of retrievals are discussed for realistic situations.

  18. The Islamic State Battle Plan: Press Release Natural Language Processing

    DTIC Science & Technology

    2016-06-01

    Processing, text mining , corpus, generalized linear model, cascade, R Shiny, leaflet, data visualization 15. NUMBER OF PAGES 83 16. PRICE CODE...Terrorism and Responses to Terrorism TDM Term Document Matrix TF Term Frequency TF-IDF Term Frequency-Inverse Document Frequency tm text mining (R...package=leaflet. Feinerer I, Hornik K (2015) Text Mining Package “tm,” Version 0.6-2. (Jul 3) https://cran.r-project.org/web/packages/tm/tm.pdf

  19. INFO-RNA--a fast approach to inverse RNA folding.

    PubMed

    Busch, Anke; Backofen, Rolf

    2006-08-01

    The structure of RNA molecules is often crucial for their function. Therefore, secondary structure prediction has gained much interest. Here, we consider the inverse RNA folding problem, which means designing RNA sequences that fold into a given structure. We introduce a new algorithm for the inverse folding problem (INFO-RNA) that consists of two parts; a dynamic programming method for good initial sequences and a following improved stochastic local search that uses an effective neighbor selection method. During the initialization, we design a sequence that among all sequences adopts the given structure with the lowest possible energy. For the selection of neighbors during the search, we use a kind of look-ahead of one selection step applying an additional energy-based criterion. Afterwards, the pre-ordered neighbors are tested using the actual optimization criterion of minimizing the structure distance between the target structure and the mfe structure of the considered neighbor. We compared our algorithm to RNAinverse and RNA-SSD for artificial and biological test sets. Using INFO-RNA, we performed better than RNAinverse and in most cases, we gained better results than RNA-SSD, the probably best inverse RNA folding tool on the market. www.bioinf.uni-freiburg.de?Subpages/software.html.

  20. Imaging electrical conductivity, permeability, and/or permittivity contrasts using the Born Scattering Inversion (BSI)

    NASA Astrophysics Data System (ADS)

    Darrh, A.; Downs, C. M.; Poppeliers, C.

    2017-12-01

    Born Scattering Inversion (BSI) of electromagnetic (EM) data is a geophysical imaging methodology for mapping weak conductivity, permeability, and/or permittivity contrasts in the subsurface. The high computational cost of full waveform inversion is reduced by adopting the First Born Approximation for scattered EM fields. This linearizes the inverse problem in terms of Born scattering amplitudes for a set of effective EM body sources within a 3D imaging volume. Estimation of scatterer amplitudes is subsequently achieved by solving the normal equations. Our present BSI numerical experiments entail Fourier transforming real-valued synthetic EM data to the frequency-domain, and minimizing the L2 residual between complex-valued observed and predicted data. We are testing the ability of BSI to resolve simple scattering models. For our initial experiments, synthetic data are acquired by three-component (3C) electric field receivers distributed on a plane above a single point electric dipole within a homogeneous and isotropic wholespace. To suppress artifacts, candidate Born scatterer locations are confined to a volume beneath the receiver array. Also, we explore two different numerical linear algebra algorithms for solving the normal equations: Damped Least Squares (DLS), and Non-Negative Least Squares (NNLS). Results from NNLS accurately recover the source location only for a large dense 3C receiver array, but fail when the array is decimated, or is restricted to horizontal component data. Using all receiver stations and all components per station, NNLS results are relatively insensitive to a sub-sampled frequency spectrum, suggesting that coarse frequency-domain sampling may be adequate for good target resolution. Results from DLS are insensitive to diminishing array density, but contain spatially oscillatory structure. DLS-generated images are consistently centered at the known point source location, despite an abundance of surrounding structure.

  1. Limitation of Inverse Probability-of-Censoring Weights in Estimating Survival in the Presence of Strong Selection Bias

    PubMed Central

    Howe, Chanelle J.; Cole, Stephen R.; Chmiel, Joan S.; Muñoz, Alvaro

    2011-01-01

    In time-to-event analyses, artificial censoring with correction for induced selection bias using inverse probability-of-censoring weights can be used to 1) examine the natural history of a disease after effective interventions are widely available, 2) correct bias due to noncompliance with fixed or dynamic treatment regimens, and 3) estimate survival in the presence of competing risks. Artificial censoring entails censoring participants when they meet a predefined study criterion, such as exposure to an intervention, failure to comply, or the occurrence of a competing outcome. Inverse probability-of-censoring weights use measured common predictors of the artificial censoring mechanism and the outcome of interest to determine what the survival experience of the artificially censored participants would be had they never been exposed to the intervention, complied with their treatment regimen, or not developed the competing outcome. Even if all common predictors are appropriately measured and taken into account, in the context of small sample size and strong selection bias, inverse probability-of-censoring weights could fail because of violations in assumptions necessary to correct selection bias. The authors used an example from the Multicenter AIDS Cohort Study, 1984–2008, regarding estimation of long-term acquired immunodeficiency syndrome-free survival to demonstrate the impact of violations in necessary assumptions. Approaches to improve correction methods are discussed. PMID:21289029

  2. Identification of SR3335 (ML176): a Synthetic RORα Selective Inverse Agonist

    PubMed Central

    Kumar, Naresh; Kojetin, Douglas J.; Solt, Laura A.; Kumar, K. Ganesh; Nuhant, Philippe; Duckett, Derek R.; Cameron, Michael D.; Butler, Andrew A.; Roush, William R.; Griffin, Patrick R.; Burris, Thomas P.

    2010-01-01

    Several nuclear receptors (NRs) are still characterized as orphan receptors since ligands have not yet been identified for these proteins. The retinoic acid receptor-related receptors (RORs) have no well-defined physiological ligands. Here, we describe the identification of a selective RORα synthetic ligand, SR3335 (ML-176). SR3335 directly binds to RORα, but not other RORs, and functions as a selective partial inverse agonist of RORα in cell-based assays. Furthermore, SR3335 suppresses the expression of endogenous RORα target genes in HepG2 involved in hepatic gluconeogenesis including glucose-6-phosphatase and phosphoenolpyruvate carboxykinase. Pharmacokinetic studies indicate that SR3335 displays reasonable exposure following an i.p. injection into mice. We assess the ability of SR3335 to suppress gluconeogenesis in vivo using a diet induced obesity (DIO) mouse model where the mice where treated with 15 mg/kg b.i.d., i.p. for 6-days followed by a pyruvate tolerance test. SR3335 treated mice displayed lower plasma glucose levels following the pyruvate challenge consistent with suppression of gluconeogenesis. Thus, we have identified the first selective synthetic RORα inverse agonist and this compound can be utilized as a chemical tool to probe the function of this receptor both in vitro and in vivo. Additionally, our data suggests that RORα inverse agonists may hold utility for suppression of elevated hepatic glucose production in type 2 diabetics. PMID:21090593

  3. Model Following and High Order Augmentation for Rotorcraft Control, Applied via Partial Authority

    NASA Astrophysics Data System (ADS)

    Spires, James Michael

    This dissertation consists of two main studies, a few small studies, and design documentation, all aimed at improving rotorcraft control by employing multi-input multi-output (MIMO) command-modelfollowing control as a baseline, together with a selectable (and de-selectable) MIMO high order compensator that augments the baseline. Two methods of MIMO command-model-following control design are compared for rotorcraft flight control. The first, Explicit Model Following (EMF), employs SISO inverse plants with a dynamic decoupling matrix, which is a purely feed-forward approach to inverting the plant. The second is Dynamic Inversion (DI), which involves both feed-forward and feedback path elements to invert the plant. The EMF design is purely linear, while the DI design has some nonlinear elements in vertical rate control. For each of these methods, an architecture is presented that provides angular rate model-following with selectable vertical rate model-following. Implementation challenges of both EMF and DI are covered, and methods of dealing with them are presented. These two MIMO model-following approaches are evaluated regarding (1) fidelity to the command model, and (2) turbulence rejection. Both are found to provide good tracking of commands and reduction of cross coupling. Next, an architecture and design methodology for high order compensator (HOC) augmentation of a baseline controller for rotorcraft is presented. With this architecture, the HOC compensator is selectable and can easily be authority-limited, which might ease certification. Also, the plant for this augmentative MIMO compensator design is a stabilized helicopter system, so good flight test data could be safely gathered for more accurate plant identification. The design methodology is carried out twice on an example helicopter model, once with turbulence rejection as the objective, and once with the additional objective of closely following pilot commands. The turbulence rejection HOC is feedback only (HOC_FB), while the combined objective HOC has both feedback and feedforward elements (HOC_FBFF). The HOC_FB was found to be better at improving turbulence rejection but generally degrades the following of pilot commands. The HOC_FBFF improves turbulence rejection relative to the Baseline controller, but not by as much as HOC_FB. However, HOC_FBFF also generally improves the following of pilot commands. Future work is suggested and facilitated in the areas of DI, MIMO EMF, and HOC augmentation. High frequency dynamics, neglected in the DI design, unexpectedly change the low frequency behavior of the DI-plant system, in addition to the expected change in high frequency dynamics. This dissertation shows why, and suggests a technique for designing a pseudo-command pre-filter that at least partially restores the intended DI-plant dynamics. For EMF, a procedure is presented that avoids use of a reducedorder model, and instead uses a full-order model or even frequency-domain flight test data. With HOC augmentation, future research might investigate the utility of adding an H? constraint to the design objective, which is known as an equal-weighting mixed-norm H2/H infinity design. Because all the formulas in the published literature either require solution of three coupled Riccati Equations (for which there is no readily available tool), or make assumptions that do not fit the present problem, appropriate equalweighting H2/H infinity design formulas are derived which involve two de-coupled Riccati Equations.

  4. Improving Estimates Of Phase Parameters When Amplitude Fluctuates

    NASA Technical Reports Server (NTRS)

    Vilnrotter, V. A.; Brown, D. H.; Hurd, W. J.

    1989-01-01

    Adaptive inverse filter applied to incoming signal and noise. Time-varying inverse-filtering technique developed to improve digital estimate of phase of received carrier signal. Intended for use where received signal fluctuates in amplitude as well as in phase and signal tracked by digital phase-locked loop that keeps its phase error much smaller than 1 radian. Useful in navigation systems, reception of time- and frequency-standard signals, and possibly spread-spectrum communication systems.

  5. Time Domain Radar Laboratory Operating System Development and Transient EM Analysis.

    DTIC Science & Technology

    1981-09-01

    polarization of the return, arg used. Other similar methods use amplitude and phase differences or special properties of Rayleigh region scattering. All these...3ptias Inverse Scattering ... 19 2. "!xact" Inverse Scattering !Nethod .. 20 3. Other Methods ................... 21 C. REVIEW OF TDRL PROGRESS AT SPS...explicit independant variable in.most methods . In the past, frequency domain analysis has been the primary means of analyzing aan-monochromatic EM

  6. Zipf's Law and Avoidance of Excessive Synonymy

    ERIC Educational Resources Information Center

    Manin, Dmitrii Y.

    2008-01-01

    Zipf's law states that if words of language are ranked in the order of decreasing frequency in texts, the frequency of a word is inversely proportional to its rank. It is very reliably observed in the data, but to date it escaped satisfactory theoretical explanation. This article suggests that Zipf's law may result from a hierarchical organization…

  7. The relation of mechanical properties of wood and nosebar pressure in the production of veneer

    Treesearch

    Charles W. McMillin

    1958-01-01

    Observations of checking frequency, depth of check penetration, veneer thickness, and surface quality were made at 20 machining conditions. An inverse relationship between depth of check and frequency of checking was established. The effect of cutting temperature was demonstrated, and strength in compression perpendicular to the grain, tension perpendicular to the...

  8. Atmospheric controls on elephant communication.

    PubMed

    Garstang, M; Larom, D; Raspet, R; Lindeque, M

    1995-04-01

    Atmospheric conditions conducive to long-range transmission of low-frequency sound as used by elephants are found to exist in the Etosha National Park in Namibia during the late dry season. Meteorological measurements show that strong temperature inversions form at the surface before sunset and decay with sunrise, often accompanied by calm wind conditions during the early evening. These observations are used in an acoustic model to determine the sensitivity of infrasound to the effects of (a) the strength, thickness and elevation of temperature inversions, and (b) the growth and decay of an inversion typical of dry, elevated African savannas. The results suggest that the range over which elephants communicate more than doubles at night. Optimum conditions occur 1-2 h after sunset on clear, relatively cold, calm nights. At these times, ranges of over 10 km are likely, with the greatest amplification occurring at the lowest frequency tested. This strong diurnal cycle in communication range may be reflected in longer-lasting changes in weather and may exert a significant influence on elephant behaviour on time scales from days to many years.

  9. Turbulent Equilibria for Charged Particles in Space

    NASA Astrophysics Data System (ADS)

    Yoon, Peter

    2017-04-01

    The solar wind electron distribution function is apparently composed of several components including non-thermal tail population. The electron distribution that contains energetic tail feature is well fitted with the kappa distribution function. The solar wind protons also possess quasi power-law tail distribution function that is well fitted with an inverse power law model. The present paper discusses the latest theoretical development regarding the dynamical steady-state solution of electrons and Langmuir turbulence that are in turbulent equilibrium. According to such a theory, the Maxwellian and kappa distribution functions for the electrons emerge as the only two possible solution that satisfy the steady-state weak turbulence plasma kinetic equation. For the proton inverse power-law tail problem, a similar turbulent equilibrium solution can be conceived of, but instead of high-frequency Langmuir fluctuation, the theory involves low-frequency kinetic Alfvenic turbulence. The steady-state solution of the self-consistent proton kinetic equation and wave kinetic equation for Alfvenic waves can be found in order to obtain a self-consistent solution for the inverse power law tail distribution function.

  10. Advanced systems requirements for ocean observations via microwave radiometers

    NASA Technical Reports Server (NTRS)

    Blume, H.-J. C.; Swift, C. T.; Kendall, B. M.

    1978-01-01

    A future microwave spectroradiometer operating in several frequency bands will have the capability to step or sweep frequencies on an adaptable or programmable basis. The on-board adaptable frequency shifting can make the systems immune from radio interference. Programmable frequency sweeping with on-board data inversion by high speed computers would provide for instantaneous synoptic measurements or sea surface temperature and salinity, water surface and volume pollution, ice thickness, ocean surface winds, snow depth, and soil moisture. Large structure satellites will allow an order of magnitude improvement in the present radiometric measurement spacial resolution.

  11. On Sagnac frequency splitting in a solid-state ring Raman laser.

    PubMed

    Liang, Wei; Savchenkov, Anatoliy; Ilchenko, Vladimir; Griffith, Robert; De Cuir, Edwin; Kim, Steven; Matsko, Andrey; Maleki, Lute

    2017-11-15

    We report on an accurate measurement of the frequency splitting of an optical rotating ring microcavity made out of calcium fluoride. By measuring the frequencies of the clockwise and counter-clockwise coherent Raman emissions confined in the cavity modes, we show that the frequency splitting is inversely proportional to the refractive index of the cavity host material. The measurement has an accuracy of 1% and unambiguously confirms the classical theoretical prediction based on special theory of relativity. This Letter also demonstrates the usefulness of the ring Raman microlaser for rotation measurements.

  12. Method for detecting a pericentric inversion in a chromosome

    DOEpatents

    Lucas, Joe N.

    2000-01-01

    A method is provided for determining a clastogenic signature of a sample of chromosomes by quantifying a frequency of a first type of chromosome aberration present in the sample; quantifying a frequency of a second, different type of chromosome aberration present in the sample; and comparing the frequency of the first type of chromosome aberration to the frequency of the second type of chromosome aberration. A method is also provided for using that clastogenic signature to identify a clastogenic agent or dosage to which the cells were exposed.

  13. Sensitivity of a Bayesian atmospheric-transport inversion model to spatio-temporal sensor resolution applied to the 2006 North Korean nuclear test

    NASA Astrophysics Data System (ADS)

    Lundquist, K. A.; Jensen, D. D.; Lucas, D. D.

    2017-12-01

    Atmospheric source reconstruction allows for the probabilistic estimate of source characteristics of an atmospheric release using observations of the release. Performance of the inversion depends partially on the temporal frequency and spatial scale of the observations. The objective of this study is to quantify the sensitivity of the source reconstruction method to sparse spatial and temporal observations. To this end, simulations of atmospheric transport of noble gasses are created for the 2006 nuclear test at the Punggye-ri nuclear test site. Synthetic observations are collected from the simulation, and are taken as "ground truth". Data denial techniques are used to progressively coarsen the temporal and spatial resolution of the synthetic observations, while the source reconstruction model seeks to recover the true input parameters from the synthetic observations. Reconstructed parameters considered here are source location, source timing and source quantity. Reconstruction is achieved by running an ensemble of thousands of dispersion model runs that sample from a uniform distribution of the input parameters. Machine learning is used to train a computationally-efficient surrogate model from the ensemble simulations. Monte Carlo sampling and Bayesian inversion are then used in conjunction with the surrogate model to quantify the posterior probability density functions of source input parameters. This research seeks to inform decision makers of the tradeoffs between more expensive, high frequency observations and less expensive, low frequency observations.

  14. Eye movements during the Rorschach test in schizophrenia.

    PubMed

    Hori, Yasuko; Fukuzako, Hiroshi; Sugimoto, Yoko; Takigawa, Morikuni

    2002-08-01

    In order to understand relationships between scanning behaviors, characteristics of visual stimuli and the clinical symptoms in schizophrenia, eye movements of 37 schizophrenic patients and 36 controls were recorded using an eye-mark recorder during a free-response period in a Rorschach test. Four cards (I, II, V and VIII) were used. Data were analyzed during 15 s from the presentation of each card. For all cards, the number of eye fixations and the number of eye fixation areas were fewer, and total scanning length and mean scanning length were shorter for schizophrenic patients than for controls. For card II, in the non-popular response group, eye fixation frequency upon area 5 + 6 (red) was higher for schizophrenic patients. For card VIII, in the popular response group, eye fixation frequency upon area 5 + 6 (pink) was lower for schizophrenic patients. For cards II and VIII, the number of eye fixations was inversely correlated with negative symptoms. For card II, total scanning length tended to be inversely correlated with negative symptoms, and mean eye fixation time was correlated with negative symptoms. The number of eye fixation areas was inversely correlated with positive symptoms. For card VIII, eye fixation frequency in a stimulative area tended to be correlated with positive symptoms. Scanning behaviors in schizophrenic patients are affected by characteristics of visual stimuli, and partially by clinical symptoms.

  15. Three dimensional inversion of magnetic survey data collected over kimberlite pipes in presence of remanent magnetization

    NASA Astrophysics Data System (ADS)

    Zhao, Pengzhi

    Magnetic method is a common geophysical technique used to explore kimberlites. The analysis and interpretation of measured magnetic data provides the information of magnetic and geometric properties of potential kimberlite pipes. A crucial parameter of kimberlite magnetic interpretation is the remanent magnetization that dominates the classification of kimberlite. However, the measured magnetic data is the total field affected by the remanent magnetization and the susceptibility. The presence of remanent magnetization can pose severe challenges to the quantitative interpretation of magnetic data by skewing or laterally shifting magnetic anomalies relative to the subsurface source (Haney and Li, 2002). Therefore, identification of remanence effects and determination of remanent magnetization are important in magnetic data interpretation. This project presents a new method to determine the magnetic and geometric properties of kimberlite pipes in the presence of strong remanent magnetization. This method consists of two steps. The first step is to estimate the total magnetization and geometric properties of magnetic anomaly. The second step is to separate the remanent magnetization from the total magnetization. In the first step, a joint parametric inversion of total-field magnetic data and its analytic signal (derived from the survey data by Fourier transform method) is used. The algorithm of the joint inversion is based on the Gauss-Newton method and it is more stable and more accurate than the separate inversion method. It has been tested with synthetic data and applied to interpret the field data from the Lac de Gras, North-West Territories of Canada. The results of the synthetic examples and the field data applications show that joint inversion can recovers the total magnetization and geometric properties of magnetic anomaly with a good data fit and stable convergence. In the second step, the remanent magnetization is separated from the total magnetization by using a determined susceptibility. The susceptibility value is estimated by using the frequency domain electromagnetic data. The inversion method is achieved by a code, named “EM1DFM”, developed by University of British Columbia was designed to construct one of four types of 1D model, using any type of geophysical frequency domain loop-loop data with one of four variations of the inversion algorithm. The results show that the susceptibility of magnetic body is recovered, even if the depth and thickness are not well estimated. This two-step process provides a new way to determine magnetic and geometric properties of kimberlite pipes in the presence of strong remanent magnetization. The joint inversion of the total-field magnetic data and its analytic signal obtains the total magnetization and geometric properties. The frequency domain EM method provides the susceptibility. As a result, the remanent magnetization can be separated from the total magnetization accurately.

  16. FIBER AND INTEGRATED OPTICS. OTHER TOPICS IN QUANTUM ELECTRONICS: Increase of the bandwidth and of the efficiency of integrated optical traveling-wave modulators

    NASA Astrophysics Data System (ADS)

    Zolotov, Evgenii M.; Pelekhatyĭ, V. M.; Tavlykaev, R. F.

    1990-05-01

    A simultaneous increase in the frequency bandwidth and a reduction in the control (drive) power of integrated optical traveling-wave modulators can be achieved as a result of the electrooptic interaction in accordance with a linear frequency-modulated oscillatory law derived by inverse Fourier transformation of a rectangular amplitude-frequency characteristic and a quadratic phase-frequency characteristic of a modulator. This oscillatory law is realized using planar electrode structures with triangular or trapezoidal toothed edges. The tooth repetition frequency is governed by the linearly frequency-modulated oscillations and it rises on increase in the light modulation frequency.

  17. The inverse problem of estimating the gravitational time dilation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gusev, A. V., E-mail: avg@sai.msu.ru; Litvinov, D. A.; Rudenko, V. N.

    2016-11-15

    Precise testing of the gravitational time dilation effect suggests comparing the clocks at points with different gravitational potentials. Such a configuration arises when radio frequency standards are installed at orbital and ground stations. The ground-based standard is accessible directly, while the spaceborne one is accessible only via the electromagnetic signal exchange. Reconstructing the current frequency of the spaceborne standard is an ill-posed inverse problem whose solution depends significantly on the characteristics of the stochastic electromagnetic background. The solution for Gaussian noise is known, but the nature of the standards themselves is associated with nonstationary fluctuations of a wide class ofmore » distributions. A solution is proposed for a background of flicker fluctuations with a spectrum (1/f){sup γ}, where 1 < γ < 3, and stationary increments. The results include formulas for the error in reconstructing the frequency of the spaceborne standard and numerical estimates for the accuracy of measuring the relativistic redshift effect.« less

  18. Uncertainty Estimation in Elastic Full Waveform Inversion by Utilising the Hessian Matrix

    NASA Astrophysics Data System (ADS)

    Hagen, V. S.; Arntsen, B.; Raknes, E. B.

    2017-12-01

    Elastic Full Waveform Inversion (EFWI) is a computationally intensive iterative method for estimating elastic model parameters. A key element of EFWI is the numerical solution of the elastic wave equation which lies as a foundation to quantify the mismatch between synthetic (modelled) and true (real) measured seismic data. The misfit between the modelled and true receiver data is used to update the parameter model to yield a better fit between the modelled and true receiver signal. A common approach to the EFWI model update problem is to use a conjugate gradient search method. In this approach the resolution and cross-coupling for the estimated parameter update can be found by computing the full Hessian matrix. Resolution of the estimated model parameters depend on the chosen parametrisation, acquisition geometry, and temporal frequency range. Although some understanding has been gained, it is still not clear which elastic parameters can be reliably estimated under which conditions. With few exceptions, previous analyses have been based on arguments using radiation pattern analysis. We use the known adjoint-state technique with an expansion to compute the Hessian acting on a model perturbation to conduct our study. The Hessian is used to infer parameter resolution and cross-coupling for different selections of models, acquisition geometries, and data types, including streamer and ocean bottom seismic recordings. Information about the model uncertainty is obtained from the exact Hessian, and is essential when evaluating the quality of estimated parameters due to the strong influence of source-receiver geometry and frequency content. Investigation is done on both a homogeneous model and the Gullfaks model where we illustrate the influence of offset on parameter resolution and cross-coupling as a way of estimating uncertainty.

  19. Retrieval of ice thickness from polarimetric SAR data

    NASA Technical Reports Server (NTRS)

    Kwok, R.; Yueh, S. H.; Nghiem, S. V.; Huynh, D. D.

    1993-01-01

    We describe a potential procedure for retrieving ice thickness from multi-frequency polarimetric SAR data for thin ice. This procedure includes first masking out the thicker ice types with a simple classifier and then deriving the thickness of the remaining pixels using a model-inversion technique. The technique used to derive ice thickness from polarimetric observations is provided by a numerical estimator or neural network. A three-layer perceptron implemented with the backpropagation algorithm is used in this investigation with several improved aspects for a faster convergence rate and a better accuracy of the neural network. These improvements include weight initialization, normalization of the output range, the selection of offset constant, and a heuristic learning algorithm. The performance of the neural network is demonstrated by using training data generated by a theoretical scattering model for sea ice matched to the database of interest. The training data are comprised of the polarimetric backscattering coefficients of thin ice and the corresponding input ice parameters to the scattering model. The retrieved ice thickness from the theoretical backscattering coefficients is compare with the input ice thickness to the scattering model to illustrate the accuracy of the inversion method. Results indicate that the network convergence rate and accuracy are higher when multi-frequency training sets are presented. In addition, the dominant backscattering coefficients in retrieving ice thickness are found by comparing the behavior of the network trained backscattering data at various incidence angels. After the neural network is trained with the theoretical backscattering data at various incidence anges, the interconnection weights between nodes are saved and applied to the experimental data to be investigated. In this paper, we illustrate the effectiveness of this technique using polarimetric SAR data collected by the JPL DC-8 radar over a sea ice scene.

  20. A model reduction approach to numerical inversion for a parabolic partial differential equation

    NASA Astrophysics Data System (ADS)

    Borcea, Liliana; Druskin, Vladimir; Mamonov, Alexander V.; Zaslavsky, Mikhail

    2014-12-01

    We propose a novel numerical inversion algorithm for the coefficients of parabolic partial differential equations, based on model reduction. The study is motivated by the application of controlled source electromagnetic exploration, where the unknown is the subsurface electrical resistivity and the data are time resolved surface measurements of the magnetic field. The algorithm presented in this paper considers inversion in one and two dimensions. The reduced model is obtained with rational interpolation in the frequency (Laplace) domain and a rational Krylov subspace projection method. It amounts to a nonlinear mapping from the function space of the unknown resistivity to the small dimensional space of the parameters of the reduced model. We use this mapping as a nonlinear preconditioner for the Gauss-Newton iterative solution of the inverse problem. The advantage of the inversion algorithm is twofold. First, the nonlinear preconditioner resolves most of the nonlinearity of the problem. Thus the iterations are less likely to get stuck in local minima and the convergence is fast. Second, the inversion is computationally efficient because it avoids repeated accurate simulations of the time-domain response. We study the stability of the inversion algorithm for various rational Krylov subspaces, and assess its performance with numerical experiments.

  1. Improved resistivity imaging of groundwater solute plumes using POD-based inversion

    NASA Astrophysics Data System (ADS)

    Oware, E. K.; Moysey, S. M.; Khan, T.

    2012-12-01

    We propose a new approach for enforcing physics-based regularization in electrical resistivity imaging (ERI) problems. The approach utilizes a basis-constrained inversion where an optimal set of basis vectors is extracted from training data by Proper Orthogonal Decomposition (POD). The key aspect of the approach is that Monte Carlo simulation of flow and transport is used to generate a training dataset, thereby intrinsically capturing the physics of the underlying flow and transport models in a non-parametric form. POD allows for these training data to be projected onto a subspace of the original domain, resulting in the extraction of a basis for the inversion that captures characteristics of the groundwater flow and transport system, while simultaneously allowing for dimensionality reduction of the original problem in the projected space We use two different synthetic transport scenarios in heterogeneous media to illustrate how the POD-based inversion compares with standard Tikhonov and coupled inversion. The first scenario had a single source zone leading to a unimodal solute plume (synthetic #1), whereas, the second scenario had two source zones that produced a bimodal plume (synthetic #2). For both coupled inversion and the POD approach, the conceptual flow and transport model used considered only a single source zone for both scenarios. Results were compared based on multiple metrics (concentration root-mean square error (RMSE), peak concentration, and total solute mass). In addition, results for POD inversion based on 3 different data densities (120, 300, and 560 data points) and varying number of selected basis images (100, 300, and 500) were compared. For synthetic #1, we found that all three methods provided qualitatively reasonable reproduction of the true plume. Quantitatively, the POD inversion performed best overall for each metric considered. Moreover, since synthetic #1 was consistent with the conceptual transport model, a small number of basis vectors (100) contained enough a priori information to constrain the inversion. Increasing the amount of data or number of selected basis images did not translate into significant improvement in imaging results. For synthetic #2, the RMSE and error in total mass were lowest for the POD inversion. However, the peak concentration was significantly overestimated by the POD approach. Regardless, the POD-based inversion was the only technique that could capture the bimodality of the plume in the reconstructed image, thus providing critical information that could be used to reconceptualize the transport problem. We also found that, in the case of synthetic #2, increasing the number of resistivity measurements and the number of selected basis vectors allowed for significant improvements in the reconstructed images.

  2. A chromosome 10 variant with a 12 Mb inversion [inv(10)(q11.22q21.1)] identical by descent and frequent in the Swedish population.

    PubMed

    Entesarian, Miriam; Carlsson, Birgit; Mansouri, Mahmoud Reza; Stattin, Eva-Lena; Holmberg, Eva; Golovleva, Irina; Stefansson, Hreinn; Klar, Joakim; Dahl, Niklas

    2009-03-01

    We identified a paracentric inversion of chromosome 10 [inv(10)(q11.22q21.1)] in 0.20% of Swedish individuals (15/7,439) referred for cytogenetic analysis. A retrospective analysis of 8,896 karyotypes from amniocenteses in Sweden revealed a carrier frequency of 0.079% (7/8,896) for the inversion. Cloning and detailed analysis of the inversion breakpoint regions show enrichment for interspersed repeat elements and AT-stretches. The centromeric breakpoint coincides with that of a predicted inversion from HapMap data, which suggests that this region is involved in several chromosome 10 variants. No known gene or predicted transcript are disrupted by the inversion which spans approximately 12 Mb. Carriers from four non-related Swedish families have identical inversion breakpoints and haplotype analysis confirmed that the rearrangement is identical by descent. Diagnosis was retrieved in 6 out of the 15 carriers referred for cytogenetic analysis. No consistent phenotype was found to be associated with the inversion. Our study demonstrates that the inv(10)(q11.22q21.1) is a rare and inherited chromosome variant with a broad geographical distribution in Sweden. 2009 Wiley-Liss, Inc.

  3. Recombination and synaptic adjustment in oocytes of mice heterozygous for a large paracentric inversion.

    PubMed

    Torgasheva, Anna A; Rubtsov, Nikolai B; Borodin, Pavel M

    2013-03-01

    Homologous chromosome synapsis in inversion heterozygotes results in the formation of inversion loops. These loops might be transformed into straight, non-homologously paired bivalents via synaptic adjustment. Synaptic adjustment was discovered 30 years ago; however, its relationship with recombination has remained unclear. We analysed this relationship in female mouse embryos heterozygous for large paracentric inversion In(1)1Rk using immunolocalisation of the synaptonemal complex (SYCP3) and mature recombination nodules (MLH1) proteins. The frequency of cells containing bivalents with inversion loops decreased from 69 % to 28 % during pachytene. If an MLH1 focus was present in the non-homologously paired inverted region of the straight bivalent, it was always located in the middle of the inversion. Most of the small, incompletely adjusted loops contained MLH1 foci near the points at which pairing partners were switched. This observation indicates that the degree of synaptic adjustment depended on the crossover position. Complete synaptic adjustment was only possible if a crossover (CO) was located exactly in the middle of the inversion. If a CO was located at any other site, this interrupted synaptic adjustment and resulted in inversion loops of different sizes with an MLH1 focus at or near the edge of the remaining loop.

  4. Seismic attenuation structure of the Seattle Basin, Washington State from explosive-source refraction data

    USGS Publications Warehouse

    Li, Q.; Wilcock, W.S.D.; Pratt, T.L.; Snelson, C.M.; Brocher, T.M.

    2006-01-01

    We used waveform data from the 1999 SHIPS (Seismic Hazard Investigation of Puget Sound) seismic refraction experiment to constrain the attenuation structure of the Seattle basin, Washington State. We inverted the spectral amplitudes of compressional- and shear-wave arrivals for source spectra, site responses, and one- and two-dimensional Q-1 models at frequencies between 1 and 40 Hz for P waves and 1 and 10 Hz for S waves. We also obtained Q-1 models from t* values calculated from the spectral slopes of P waves between 10 and 40 Hz. One-dimensional inversions show that Qp at the surface is 22 at 1 Hz, 130 at 5 Hz, and 390 at 20 Hz. The corresponding values at 18 km depth are 100, 440, and 1900. Qs at the surface is 16 and 160 at 1 Hz and 8 Hz, respectively, increasing to 80 and 500 at 18 km depth. The t* inversion yields a Qp model that is consistent with the amplitude inversions at 20 and 30 Hz. The basin geometry is clearly resolved in the t* inversion, but the amplitude inversions only imaged the basin structure after removing anomalously high-amplitude shots near Seattle. When these shots are removed, we infer that Q-1 values may be ???30% higher in the center of the basin than the one-dimensional models predict. We infer that seismic attenuation in the Seattle basin will significantly reduce ground motions at frequencies at and above 1 Hz, partially countering amplification effects within the basin.

  5. Approximate non-linear multiparameter inversion for multicomponent single and double P-wave scattering in isotropic elastic media

    NASA Astrophysics Data System (ADS)

    Ouyang, Wei; Mao, Weijian

    2018-03-01

    An asymptotic quadratic true-amplitude inversion method for isotropic elastic P waves is proposed to invert medium parameters. The multicomponent P-wave scattered wavefield is computed based on a forward relationship using second-order Born approximation and corresponding high-frequency ray theoretical methods. Within the local double scattering mechanism, the P-wave transmission factors are elaborately calculated, which results in the radiation pattern for P-waves scattering being a quadratic combination of the density and Lamé's moduli perturbation parameters. We further express the elastic P-wave scattered wavefield in a form of generalized Radon transform (GRT). After introducing classical backprojection operators, we obtain an approximate solution of the inverse problem by solving a quadratic non-linear system. Numerical tests with synthetic data computed by finite-differences scheme demonstrate that our quadratic inversion can accurately invert perturbation parameters for strong perturbations, compared with the P-wave single-scattering linear inversion method. Although our inversion strategy here is only syncretized with P-wave scattering, it can be extended to invert multicomponent elastic data containing both P-wave and S-wave information.

  6. Approximate nonlinear multiparameter inversion for multicomponent single and double P-wave scattering in isotropic elastic media

    NASA Astrophysics Data System (ADS)

    Ouyang, Wei; Mao, Weijian

    2018-07-01

    An asymptotic quadratic true-amplitude inversion method for isotropic elastic P waves is proposed to invert medium parameters. The multicomponent P-wave scattered wavefield is computed based on a forward relationship using second-order Born approximation and corresponding high-frequency ray theoretical methods. Within the local double scattering mechanism, the P-wave transmission factors are elaborately calculated, which results in the radiation pattern for P-wave scattering being a quadratic combination of the density and Lamé's moduli perturbation parameters. We further express the elastic P-wave scattered wavefield in a form of generalized Radon transform. After introducing classical backprojection operators, we obtain an approximate solution of the inverse problem by solving a quadratic nonlinear system. Numerical tests with synthetic data computed by finite-differences scheme demonstrate that our quadratic inversion can accurately invert perturbation parameters for strong perturbations, compared with the P-wave single-scattering linear inversion method. Although our inversion strategy here is only syncretized with P-wave scattering, it can be extended to invert multicomponent elastic data containing both P- and S-wave information.

  7. Zero-crossing approach to high-resolution reconstruction in frequency-domain optical-coherence tomography.

    PubMed

    Krishnan, Sunder Ram; Seelamantula, Chandra Sekhar; Bouwens, Arno; Leutenegger, Marcel; Lasser, Theo

    2012-10-01

    We address the problem of high-resolution reconstruction in frequency-domain optical-coherence tomography (FDOCT). The traditional method employed uses the inverse discrete Fourier transform, which is limited in resolution due to the Heisenberg uncertainty principle. We propose a reconstruction technique based on zero-crossing (ZC) interval analysis. The motivation for our approach lies in the observation that, for a multilayered specimen, the backscattered signal may be expressed as a sum of sinusoids, and each sinusoid manifests as a peak in the FDOCT reconstruction. The successive ZC intervals of a sinusoid exhibit high consistency, with the intervals being inversely related to the frequency of the sinusoid. The statistics of the ZC intervals are used for detecting the frequencies present in the input signal. The noise robustness of the proposed technique is improved by using a cosine-modulated filter bank for separating the input into different frequency bands, and the ZC analysis is carried out on each band separately. The design of the filter bank requires the design of a prototype, which we accomplish using a Kaiser window approach. We show that the proposed method gives good results on synthesized and experimental data. The resolution is enhanced, and noise robustness is higher compared with the standard Fourier reconstruction.

  8. On Strong Positive Frequency Dependencies of Quality Factors in Local-Earthquake Seismic Studies

    NASA Astrophysics Data System (ADS)

    Morozov, Igor B.; Jhajhria, Atul; Deng, Wubing

    2018-03-01

    Many observations of seismic waves from local earthquakes are interpreted in terms of the frequency-dependent quality factor Q( f ) = Q0 f^{η } , where η is often close to or exceeds one. However, such steep positive frequency dependencies of Q require careful analysis with regard to their physical consistency. In particular, the case of η = 1 corresponds to frequency-independent (elastic) amplitude decays with time and consequently requires no Q-type attenuation mechanisms. For η > 1, several problems with physical meanings of such Q-factors occur. First, contrary to the key premise of seismic attenuation, high-frequency parts of the wavefield are enhanced with increasing propagation times relative to the low-frequency ones. Second, such attenuation cannot be implemented by mechanical models of wave-propagating media. Third, with η > 1, the velocity dispersion associated with such Q(f) occurs over unrealistically short frequency range and has an unexpected oscillatory shape. Cases η = 1 and η > 1 are usually attributed to scattering; however, this scattering must exhibit fortuitous tuning into the observation frequency band, which appears unlikely. The reason for the above problems is that the inferred Q values are affected by the conventional single-station measurement procedure. Both parameters Q 0 and are apparent, i.e., dependent on the selected parameterization and inversion method, and they should not be directly attributed to the subsurface. For η ≈ 1, parameter Q 0 actually describes the frequency-independent amplitude decay in access of some assumed geometric spreading t -α , where α is usually taken equal one. The case η > 1 is not allowed physically and could serve as an indicator of problematic interpretations. Although the case 0 < η < 1 is possible, its parameters Q 0 and may also be biased by the measurement procedure. To avoid such difficulties of Q-based approaches, we recommend measuring and interpreting the amplitude-decay rates (such as parameter α) directly.

  9. Human inversions and their functional consequences

    PubMed Central

    Puig, Marta; Casillas, Sònia; Villatoro, Sergi

    2015-01-01

    Polymorphic inversions are a type of structural variants that are difficult to analyze owing to their balanced nature and the location of breakpoints within complex repeated regions. So far, only a handful of inversions have been studied in detail in humans and current knowledge about their possible functional effects is still limited. However, inversions have been related to phenotypic changes and adaptation in multiple species. In this review, we summarize the evidences of the functional impact of inversions in the human genome. First, given that inversions have been shown to inhibit recombination in heterokaryotes, chromosomes displaying different orientation are expected to evolve independently and this may lead to distinct gene-expression patterns. Second, inversions have a role as disease-causing mutations both by directly affecting gene structure or regulation in different ways, and by predisposing to other secondary arrangements in the offspring of inversion carriers. Finally, several inversions show signals of being selected during human evolution. These findings illustrate the potential of inversions to have phenotypic consequences also in humans and emphasize the importance of their inclusion in genome-wide association studies. PMID:25998059

  10. Assessment of the apparent bending stiffness and damping of multilayer plates; modelling and experiment

    NASA Astrophysics Data System (ADS)

    Ege, Kerem; Roozen, N. B.; Leclère, Quentin; Rinaldi, Renaud G.

    2018-07-01

    In the context of aeronautics, automotive and construction applications, the design of light multilayer plates with optimized vibroacoustical damping and isolation performances remains a major industrial challenge and a hot topic of research. This paper focuses on the vibrational behavior of three-layered sandwich composite plates in a broad-band frequency range. Several aspects are studied through measurement techniques and analytical modelling of a steel/polymer/steel plate sandwich system. A contactless measurement of the velocity field of plates using a scanning laser vibrometer is performed, from which the equivalent single layer complex rigidity (apparent bending stiffness and apparent damping) in the mid/high frequency ranges is estimated. The results are combined with low/mid frequency estimations obtained with a high-resolution modal analysis method so that the frequency dependent equivalent Young's modulus and equivalent loss factor of the composite plate are identified for the whole [40 Hz-20 kHz] frequency band. The results are in very good agreement with an equivalent single layer analytical modelling based on wave propagation analysis (model of Guyader). The comparison with this model allows identifying the frequency dependent complex modulus of the polymer core layer through inverse resolution. Dynamical mechanical analysis measurements are also performed on the polymer layer alone and compared with the values obtained through the inverse method. Again, a good agreement between these two estimations over the broad-band frequency range demonstrates the validity of the approach.

  11. FG7142, yohimbine, and βCCE produce anxiogenic-like effects in the elevated plus-maze but do not affect brainstem activated hippocampal theta.

    PubMed

    Yeung, Michelle; Lu, Lily; Hughes, Adam M; Treit, Dallas; Dickson, Clayton T

    2013-12-01

    The neurobiological underpinnings of anxiety are of paramount importance to selective and efficacious pharmaceutical intervention. Hippocampal theta frequency in urethane anaesthetized rats is suppressed by all known (and some previously unknown) anti-anxiety (anxiolytic) drugs. Although these findings support the predictive validity of this assay, its construct validity (i.e., whether theta frequency actually indexes anxiety per se) has not been a subject of systematic investigation. We reasoned that if anxiolytic drugs suppress hippocampal theta frequency, then drugs that increase anxiety (i.e., anxiogenic agents) should increase theta frequency, thus providing evidence of construct validity. We used three proven anxiogenic drugs--two benzodiazepine receptor inverse agonists, N-methyl-β-carboline-3-carboxamide (FG7142) and β-carboline-3-carboxylate ethyl ester (βCCE), and one α2 noradrenergic receptor antagonist, 17α-hydroxy-yohimban-16α-carboxylic acid methyl ester (yohimbine) as pharmacological probes to assess the construct validity of the theta model. Although all three anxiogenic drugs significantly increased behavioural measures of anxiety in the elevated plus-maze, none of the three increased the frequency of hippocampal theta oscillations in the neurophysiological model. As a positive control, we demonstrated that diazepam, a proven anxiolytic drug, decreased the frequency of hippocampal theta, as in all other studies using this model. Given this discrepancy between the significant effects of anxiogenic drugs in the behavioural model and the null effects of these drugs in the neurophysiological model, we conclude that the construct validity of the hippocampal theta model of anxiety is questionable. Copyright © 2013 Elsevier Ltd. All rights reserved.

  12. Solar wind electron densities from Viking dual-frequency radio measurements

    NASA Technical Reports Server (NTRS)

    Muhleman, D. O.; Anderson, J. D.

    1981-01-01

    Simultaneous phase coherent, two-frequency measurements of the time delay between the earth station and the Viking spacecraft have been analyzed in terms of the electron density profiles from 4 solar radii to 200 solar radii. The measurements were made during a period of solar activity minimum (1976-1977) and show a strong solar latitude effect. The data were analyzed with both a model independent, direct numerical inversion technique and with model fitting, yielding essentially the same results. It is shown that the solar wind density can be represented by two power laws near the solar equator proportional to r exp -2.7 and r exp -2.04. However, the more rapidly falling term quickly disappears at moderate latitudes (approximately 20 deg) leaving only the inverse-square behavior.

  13. Effect of bird maneuver on frequency-domain helicopter EM response

    USGS Publications Warehouse

    Fitterman, D.V.; Yin, C.

    2004-01-01

    Bird maneuver, the rotation of the coil-carrying instrument pod used for frequency-domain helicopter electromagnetic surveys, changes the nominal geometric relationship between the bird-coil system and the ground. These changes affect electromagnetic coupling and can introduce errors in helicopter electromagnetic, (HEM) data. We analyze these effects for a layered half-space for three coil configurations: vertical coaxial, vertical coplanar, and horizontal coplanar. Maneuver effect is shown to have two components: one that is purely geometric and another that is inductive in nature. The geometric component is significantly larger. A correction procedure is developed using an iterative approach that uses standard HEM inversion routines. The maneuver effect correction reduces inversion misfit error and produces laterally smoother cross sections than obtained from uncorrected data. ?? 2004 Society of Exploration Geophysicists. All rights reserved.

  14. Inversion of time-domain induced polarization data based on time-lapse concept

    NASA Astrophysics Data System (ADS)

    Kim, Bitnarae; Nam, Myung Jin; Kim, Hee Joon

    2018-05-01

    Induced polarization (IP) surveys, measuring overvoltage phenomena of the medium, are widely and increasingly performed not only for exploration of mineral resources but also for engineering applications. Among several IP survey methods such as time-domain, frequency-domain and spectral IP surveys, this study introduces a noble inversion method for time-domain IP data to recover the chargeability structure of target medium. The inversion method employs the concept of 4D inversion of time-lapse resistivity data sets, considering the fact that measured voltage in time-domain IP survey is distorted by IP effects to increase from the instantaneous voltage measured at the moment the source current injection starts. Even though the increase is saturated very fast, we can consider the saturated and instantaneous voltages as a time-lapse data set. The 4D inversion method is one of the most powerful method for inverting time-lapse resistivity data sets. Using the developed IP inversion algorithm, we invert not only synthetic but also field IP data to show the effectiveness of the proposed method by comparing the recovered chargeability models with those from linear inversion that was used for the inversion of the field data in a previous study. Numerical results confirm that the proposed inversion method generates reliable chargeability models even though the anomalous bodies have large IP effects.

  15. Numerical Representation of Wintertime Near-Surface Inversions in the Arctic with a 2.5-km Version of the Global Environmental Multiscale (GEM) Model

    NASA Astrophysics Data System (ADS)

    Dehghan, A.; Mariani, Z.; Gascon, G.; Bélair, S.; Milbrandt, J.; Joe, P. I.; Crawford, R.; Melo, S.

    2017-12-01

    Environment and Climate Change Canada (ECCC) is implementing a 2.5-km resolution version of the Global Environmental Multiscale (GEM) model over the Canadian Arctic. Radiosonde observations were used to evaluate the numerical representation of surface-based temperature inversion which is a major feature in the Arctic region. Arctic surface-based inversions are often created by imbalance between radiative cooling processes at surface and warm air advection above. This can have a significant effect on vertical mixing of pollutants and moisture, and ultimately, on cloud formation. It is therefore important to correctly predict the existence of surface inversions along with their characteristics (i.e., intensity and depth). Previous climatological studies showed that the frequency and intensity of surface-based inversions are larger during colder months in the Arctic. Therefore, surface-based inversions were estimated using radiosonde measurements during winter (December 2015 to February 2016) at Iqaluit (Nunavut, Canada). Results show that the inversion intensity can exceed 10 K with depths as large as 1 km. Preliminary evaluation of GEM outputs reveals that the model tends to underestimate the intensity of near-surface inversions, and in some cases, the model failed to predict an inversion. This study presents the factors contributing to this bias including surface temperature and snow cover.

  16. Chromosome-wide linkage disequilibrium caused by an inversion polymorphism in the white-throated sparrow (Zonotrichia albicollis).

    PubMed

    Huynh, L Y; Maney, D L; Thomas, J W

    2011-04-01

    Chromosomal inversions have been of long-standing interest to geneticists because they are capable of suppressing recombination and facilitating the formation of adaptive gene complexes. An exceptional inversion polymorphism (ZAL2(m)) in the white-throated sparrow (Zonotrichia albicollis) is linked to variation in plumage, social behavior and mate choice, and is maintained in the population by negative assortative mating. The ZAL2(m) polymorphism is a complex inversion spanning > 100 Mb and has been proposed to be a strong suppressor of recombination, as well as a potential model for studying neo-sex chromosome evolution. To quantify and evaluate these features of the ZAL2(m) polymorphism, we generated sequence from 8 ZAL2(m) and 16 ZAL2 chromosomes at 58 loci inside and 4 loci outside the inversion. Inside the inversion we found that recombination was completely suppressed between ZAL2 and ZAL2(m), resulting in uniformly high levels of genetic differentiation (F(ST)=0.94), the formation of two distinct haplotype groups representing the alternate chromosome arrangements and extensive linkage disequilibrium spanning ~104 Mb within the inversion, whereas gene flow was not suppressed outside the inversion. Finally, although ZAL2(m) homozygotes are exceedingly rare in the population, occurring at a frequency of < 1%, we detected evidence of historical recombination between ZAL2(m) chromosomes inside the inversion, refuting its potential status as a non-recombining autosome.

  17. Estimating accidental pollutant releases in the built environment from turbulent concentration signals

    NASA Astrophysics Data System (ADS)

    Ben Salem, N.; Salizzoni, P.; Soulhac, L.

    2017-01-01

    We present an inverse atmospheric model to estimate the mass flow rate of an impulsive source of pollutant, whose position is known, from concentration signals registered at receptors placed downwind of the source. The originality of this study is twofold. Firstly, the inversion is performed using high-frequency fluctuating, i.e. turbulent, concentration signals. Secondly, the inverse algorithm is applied to a dispersion process within a dense urban canopy, at the district scale, and a street network model, SIRANERISK, is adopted. The model, which is tested against wind tunnel experiments, simulates the dispersion of short-duration releases of pollutant in different typologies of idealised urban geometries. Results allow us to discuss the reliability of the inverse model as an operational tool for crisis management and the risk assessments related to the accidental release of toxic and flammable substances.

  18. Inverse source problems in elastodynamics

    NASA Astrophysics Data System (ADS)

    Bao, Gang; Hu, Guanghui; Kian, Yavar; Yin, Tao

    2018-04-01

    We are concerned with time-dependent inverse source problems in elastodynamics. The source term is supposed to be the product of a spatial function and a temporal function with compact support. We present frequency-domain and time-domain approaches to show uniqueness in determining the spatial function from wave fields on a large sphere over a finite time interval. The stability estimate of the temporal function from the data of one receiver and the uniqueness result using partial boundary data are proved. Our arguments rely heavily on the use of the Fourier transform, which motivates inversion schemes that can be easily implemented. A Landweber iterative algorithm for recovering the spatial function and a non-iterative inversion scheme based on the uniqueness proof for recovering the temporal function are proposed. Numerical examples are demonstrated in both two and three dimensions.

  19. Joint inversion of fundamental and higher mode Rayleigh waves

    USGS Publications Warehouse

    Luo, Y.-H.; Xia, J.-H.; Liu, J.-P.; Liu, Q.-S.

    2008-01-01

    In this paper, we analyze the characteristics of the phase velocity of fundamental and higher mode Rayleigh waves in a six-layer earth model. The results show that fundamental mode is more sensitive to the shear velocities of shallow layers (< 7 m) and concentrated in a very narrow band (around 18 Hz) while higher modes are more sensitive to the parameters of relatively deeper layers and distributed over a wider frequency band. These properties provide a foundation of using a multi-mode joint inversion to define S-wave velocity. Inversion results of both synthetic data and a real-world example demonstrate that joint inversion with the damped least squares method and the SVD (Singular Value Decomposition) technique to invert Rayleigh waves of fundamental and higher modes can effectively reduce the ambiguity and improve the accuracy of inverted S-wave velocities.

  20. Inverse random source scattering for the Helmholtz equation in inhomogeneous media

    NASA Astrophysics Data System (ADS)

    Li, Ming; Chen, Chuchu; Li, Peijun

    2018-01-01

    This paper is concerned with an inverse random source scattering problem in an inhomogeneous background medium. The wave propagation is modeled by the stochastic Helmholtz equation with the source driven by additive white noise. The goal is to reconstruct the statistical properties of the random source such as the mean and variance from the boundary measurement of the radiated random wave field at multiple frequencies. Both the direct and inverse problems are considered. We show that the direct problem has a unique mild solution by a constructive proof. For the inverse problem, we derive Fredholm integral equations, which connect the boundary measurement of the radiated wave field with the unknown source function. A regularized block Kaczmarz method is developed to solve the ill-posed integral equations. Numerical experiments are included to demonstrate the effectiveness of the proposed method.

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