Appearance-based multimodal human tracking and identification for healthcare in the digital home.

PubMed

Yang, Mau-Tsuen; Huang, Shen-Yen

2014-08-05

There is an urgent need for intelligent home surveillance systems to provide home security, monitor health conditions, and detect emergencies of family members. One of the fundamental problems to realize the power of these intelligent services is how to detect, track, and identify people at home. Compared to RFID tags that need to be worn all the time, vision-based sensors provide a natural and nonintrusive solution. Observing that body appearance and body build, as well as face, provide valuable cues for human identification, we model and record multi-view faces, full-body colors and shapes of family members in an appearance database by using two Kinects located at a home's entrance. Then the Kinects and another set of color cameras installed in other parts of the house are used to detect, track, and identify people by matching the captured color images with the registered templates in the appearance database. People are detected and tracked by multisensor fusion (Kinects and color cameras) using a Kalman filter that can handle duplicate or partial measurements. People are identified by multimodal fusion (face, body appearance, and silhouette) using a track-based majority voting. Moreover, the appearance-based human detection, tracking, and identification modules can cooperate seamlessly and benefit from each other. Experimental results show the effectiveness of the human tracking across multiple sensors and human identification considering the information of multi-view faces, full-body clothes, and silhouettes. The proposed home surveillance system can be applied to domestic applications in digital home security and intelligent healthcare.

Appearance-Based Multimodal Human Tracking and Identification for Healthcare in the Digital Home

PubMed Central

Yang, Mau-Tsuen; Huang, Shen-Yen

2014-01-01

There is an urgent need for intelligent home surveillance systems to provide home security, monitor health conditions, and detect emergencies of family members. One of the fundamental problems to realize the power of these intelligent services is how to detect, track, and identify people at home. Compared to RFID tags that need to be worn all the time, vision-based sensors provide a natural and nonintrusive solution. Observing that body appearance and body build, as well as face, provide valuable cues for human identification, we model and record multi-view faces, full-body colors and shapes of family members in an appearance database by using two Kinects located at a home's entrance. Then the Kinects and another set of color cameras installed in other parts of the house are used to detect, track, and identify people by matching the captured color images with the registered templates in the appearance database. People are detected and tracked by multisensor fusion (Kinects and color cameras) using a Kalman filter that can handle duplicate or partial measurements. People are identified by multimodal fusion (face, body appearance, and silhouette) using a track-based majority voting. Moreover, the appearance-based human detection, tracking, and identification modules can cooperate seamlessly and benefit from each other. Experimental results show the effectiveness of the human tracking across multiple sensors and human identification considering the information of multi-view faces, full-body clothes, and silhouettes. The proposed home surveillance system can be applied to domestic applications in digital home security and intelligent healthcare. PMID:25098207

Multiple regression based imputation for individualizing template human model from a small number of measured dimensions.

PubMed

Nohara, Ryuki; Endo, Yui; Murai, Akihiko; Takemura, Hiroshi; Kouchi, Makiko; Tada, Mitsunori

2016-08-01

Individual human models are usually created by direct 3D scanning or deforming a template model according to the measured dimensions. In this paper, we propose a method to estimate all the necessary dimensions (full set) for the human model individualization from a small number of measured dimensions (subset) and human dimension database. For this purpose, we solved multiple regression equation from the dimension database given full set dimensions as the objective variable and subset dimensions as the explanatory variables. Thus, the full set dimensions are obtained by simply multiplying the subset dimensions to the coefficient matrix of the regression equation. We verified the accuracy of our method by imputing hand, foot, and whole body dimensions from their dimension database. The leave-one-out cross validation is employed in this evaluation. The mean absolute errors (MAE) between the measured and the estimated dimensions computed from 4 dimensions (hand length, breadth, middle finger breadth at proximal, and middle finger depth at proximal) in the hand, 2 dimensions (foot length, breadth, and lateral malleolus height) in the foot, and 1 dimension (height) and weight in the whole body are computed. The average MAE of non-measured dimensions were 4.58% in the hand, 4.42% in the foot, and 3.54% in the whole body, while that of measured dimensions were 0.00%.

Development of microgravity, full body functional reach envelope using 3-D computer graphic models and virtual reality technology

NASA Technical Reports Server (NTRS)

Lindsey, Patricia F.

1994-01-01

In microgravity conditions mobility is greatly enhanced and body stability is difficult to achieve. Because of these difficulties, optimum placement and accessibility of objects and controls can be critical to required tasks on board shuttle flights or on the proposed space station. Anthropometric measurement of the maximum reach of occupants of a microgravity environment provide knowledge about maximum functional placement for tasking situations. Calculations for a full body, functional reach envelope for microgravity environments are imperative. To this end, three dimensional computer modeled human figures, providing a method of anthropometric measurement, were used to locate the data points that define the full body, functional reach envelope. Virtual reality technology was utilized to enable an occupant of the microgravity environment to experience movement within the reach envelope while immersed in a simulated microgravity environment.

Categorical ERP Repetition Effects for Human and Furniture Items in 7-Month-Old Infants

ERIC Educational Resources Information Center

Peykarjou, Stefanie; Wissner, Julia; Pauen, Sabina

2017-01-01

Behavioural and recent neural evidence indicates that young infants discriminate broad stimulus categories. However, little is known about the categorical perception of humans represented as full bodies with heads and their discrimination from inanimate objects. This study compares infants' brain processing of human and furniture pictures, probing…

Study of human phonation in a full-body domain

NASA Astrophysics Data System (ADS)

Saurabh, Shakti; Bodony, Daniel

2015-11-01

The generation and propagation of the human voice is studied in two-dimensions using a full-body domain, using direct numerical simulation. The fluid/air in the vocal tract is modeled as a compressible and viscous fluid interacting with the non-linear, viscoelastic vocal folds (VF). The VF tissue material properties are multi-layered, with varying stiffness, and a finite-strain model is utilized and implemented in a quadratic finite element code. The fluid-solid domains are coupled through a boundary-fitted interface and utilize a Poisson equation-based mesh deformation method. The full-body domain includes the near VF region, the vocal tract, a simplified model of the soft palate and mouth, and extends out into the acoustic far-field. A new kind of inflow boundary condition based upon a quasi-one-dimensional formulation with constant sub-glottal volume velocity, which is linked to the VF movement, has been adopted. The sound pressure levels (SPL) measured are realistic and we analyze their connection to the VF dynamics and glottal and vocal tract geometries. Supported by the National Science Foundation (CAREER award number 1150439).

Asymmetric Action in the Human Newborn: Sex Differences in Patterns of Organization.

ERIC Educational Resources Information Center

Grattan, Mary P.; And Others

1992-01-01

Examined asymmetries in movement behaviors of 36 full-term, newborn infants. The majority of infants had right-biased movement behaviors. Multiple subsystems, rather than a single asymmetric system, appeared to control asymmetric action of different body regions. There were sex differences in asymmetry of distal lower body movement behaviors that…

The Naked Truth: The Face and Body Sensitive N170 Response Is Enhanced for Nude Bodies

PubMed Central

Hietanen, Jari K.; Nummenmaa, Lauri

2011-01-01

Recent event-related potential studies have shown that the occipitotemporal N170 component - best known for its sensitivity to faces - is also sensitive to perception of human bodies. Considering that in the timescale of evolution clothing is a relatively new invention that hides the bodily features relevant for sexual selection and arousal, we investigated whether the early N170 brain response would be enhanced to nude over clothed bodies. In two experiments, we measured N170 responses to nude bodies, bodies wearing swimsuits, clothed bodies, faces, and control stimuli (cars). We found that the N170 amplitude was larger to opposite and same-sex nude vs. clothed bodies. Moreover, the N170 amplitude increased linearly as the amount of clothing decreased from full clothing via swimsuits to nude bodies. Strikingly, the N170 response to nude bodies was even greater than that to faces, and the N170 amplitude to bodies was independent of whether the face of the bodies was visible or not. All human stimuli evoked greater N170 responses than did the control stimulus. Autonomic measurements and self-evaluations showed that nude bodies were affectively more arousing compared to the other stimulus categories. We conclude that the early visual processing of human bodies is sensitive to the visibility of the sex-related features of human bodies and that the visual processing of other people's nude bodies is enhanced in the brain. This enhancement is likely to reflect affective arousal elicited by nude bodies. Such facilitated visual processing of other people's nude bodies is possibly beneficial in identifying potential mating partners and competitors, and for triggering sexual behavior. PMID:22110574

3D body scanning technology for fashion and apparel industry

NASA Astrophysics Data System (ADS)

D'Apuzzo, Nicola

2007-01-01

This paper presents an overview of 3D body scanning technologies with applications to the fashion and apparel industry. Complete systems for the digitization of the human body exist since more than fifteen years. One of the main users of this technology with application in the textile field was the military industry. In fact, body scanning technology is being successfully employed since many years in military bases for a fast selection of the correct size of uniforms for the entire staff. Complete solutions were especially developed for this field of application. Many different research projects were issued for the exploitation of the same technology in the commercial field. Experiments were performed and start-up projects are to time running in different parts of the world by installing full body scanning systems in various locations such as shopping malls, boutiques or dedicated scanning centers. Everything is actually ready to be exploited and all the required hardware, software and solutions are available: full body scanning systems, software for the automatic and reliable extraction of body measurements, e-kiosk and web solutions for the presentation of garments, high-end and low-end virtual-try-on systems. However, complete solutions in this area have still not yet found the expected commercial success. Today, with the on-going large cost reduction given by the appearance of new competitors, methods for digitization of the human body becomes more interesting for the fashion and apparel industry. Therefore, a large expansion of these technologies is expected in the near future. To date, different methods are used commercially for the measurement of the human body. These can be divided into three major distinguished groups: laser-scanning, projection of light patterns, combination modeling and image processing. The different solutions have strengths and weaknesses that profile their suitability for specific applications. This paper gives an overview of their differences and characteristics and expresses clues for the selection of the adequate method. A special interest is given to practical examples of the commercial exploitation of human body digitization with applications to the fashion and apparel industry.

Evaluation of the stepwise collimation method for the reduction of the patient dose in full spine radiography

NASA Astrophysics Data System (ADS)

Lee, Boram; Lee, Sunyoung; Yang, Injeong; Yoon, Myeonggeun

2014-05-01

The purpose of this study is to evaluate the dose reduction when using the stepwise collimation method for scoliosis patients undergoing full spine radiography. A Monte Carlo simulation was carried out to acquire dose vs. volume data for organs at risk (OAR) in the human body. While the effective doses in full spine radiography were reduced by 8, 15, 27 and 44% by using four different sizes of the collimation, the doses to the skin were reduced by 31, 44, 55 and 66%, indicating that the reduction of the dose to the skin is higher than that to organs inside the body. Although the reduction rates were low for the gonad, being 9, 14, 18 and 23%, there was more than a 30% reduction in the dose to the heart, suggesting that the dose reduction depends significantly on the location of the OARs in the human body. The reduction rate of the secondary cancer risk based on the excess absolute risk (EAR) varied from 0.6 to 3.4 per 10,000 persons, depending on the size of the collimation. Our results suggest that the stepwise collimation method in full spine radiography can effectively reduce the patient dose and the radiation-induced secondary cancer risk.

Electromagnetic Wave Propagation in Body Area Networks Using the Finite-Difference-Time-Domain Method

PubMed Central

Bringuier, Jonathan N.; Mittra, Raj

2012-01-01

A rigorous full-wave solution, via the Finite-Difference-Time-Domain (FDTD) method, is performed in an attempt to obtain realistic communication channel models for on-body wireless transmission in Body-Area-Networks (BANs), which are local data networks using the human body as a propagation medium. The problem of modeling the coupling between body mounted antennas is often not amenable to attack by hybrid techniques owing to the complex nature of the human body. For instance, the time-domain Green's function approach becomes more involved when the antennas are not conformal. Furthermore, the human body is irregular in shape and has dispersion properties that are unique. One consequence of this is that we must resort to modeling the antenna network mounted on the body in its entirety, and the number of degrees of freedom (DoFs) can be on the order of billions. Even so, this type of problem can still be modeled by employing a parallel version of the FDTD algorithm running on a cluster. Lastly, we note that the results of rigorous simulation of BANs can serve as benchmarks for comparison with the abundance of measurement data. PMID:23012575

[The silence of a body and speech set free].

PubMed

Corcos, Maurice

Anorexia is a reflection of issues with the body in all its states. The social body and the representation of a model's body, mistreated in order to meet certain standards, the medical body shaken by the mystery of anorexia, and the subjective body and the reality of the flesh. The anorexic body is a testament to a past full of pain and neglect, a sign of emotional deficiency. Caring for the body of a person with anorexia, whatever the approach, means also and above all working with the future of a human being. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

Reconfigurable antenna options for 2.45/5 GHz wireless body area networks in healthcare applications.

PubMed

Abbas, Syed Muzahir; Ranga, Yogesh; Esselle, Karu P

2015-01-01

This paper presents electronically reconfigurable antenna options in healthcare applications. They are suitable for wireless body area network devices operating in the industrial, scientific, and medical (ISM) band at 2.45 GHz and IEEE 802.11 Wireless Local Area Network (WLAN) band at 5 GHz (5.15-5.35 GHz, 5.25-5.35 GHz). Two types of antennas are investigated: Antenna-I has a full ground plane and Antenna-II has a partial ground plane. The proposed antennas provide ISM operation in one mode while in another mode they support 5 GHz WLAN band. Their performance is assessed for body centric wireless communication using a simplified human body model. Antenna sensitivity to the gap between the antenna and the human body is investigated for both modes of each antenna. The proposed antennas exhibit a wide radiation pattern along the body surface to provide wide coverage and their small width (14 mm) makes them suitable for on-body communication in healthcare applications.

SU-F-T-114: A Novel Anatomically Predictive Extension Model of Computational Human Phantoms for Dose Reconstruction in Retrospective Epidemiological Studies of Second Cancer Risks in Radiotherapy Patients

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kuzmin, G; Lee, C; Lee, C

Purpose: Recent advances in cancer treatments have greatly increased the likelihood of post-treatment patient survival. Secondary malignancies, however, have become a growing concern. Epidemiological studies determining secondary effects in radiotherapy patients require assessment of organ-specific dose both inside and outside the treatment field. An essential input for Monte Carlo modeling of particle transport is radiological images showing full patient anatomy. However, in retrospective studies it is typical to only have partial anatomy from CT scans used during treatment planning. In this study, we developed a multi-step method to extend such limited patient anatomy to full body anatomy for estimating dosemore » to normal tissues located outside the CT scan coverage. Methods: The first step identified a phantom from a library of body size-dependent computational human phantoms by matching the height and weight of patients. Second, a Python algorithm matched the patient CT coverage location in relation to the whole body phantom. Third, an algorithm cut the whole body phantom and scaled them to match the size of the patient. Then, merged the two anatomies into one whole body. We entitled this new approach, Anatomically Predictive Extension (APE). Results: The APE method was examined by comparing the original chest-abdomen-pelvis CT images of the five patients with the APE phantoms developed from only the chest part of the CAP images and whole body phantoms. We achieved average percent differences of tissue volumes of 25.7%, 34.2%, 16.5%, 26.8%, and 31.6% with an average of 27% across all patients. Conclusion: Our APE method extends the limited CT patient anatomy to whole body anatomy by using image processing and computational human phantoms. Our ongoing work includes evaluating the accuracy of these APE phantoms by comparing normal tissue doses in the APE phantoms and doses calculated for the original full CAP images under generic radiotherapy simulations. This research was supported by the NIH Intramural Research Program.« less

Stem Cells, Science, and Public Reasoning

ERIC Educational Resources Information Center

Hurlbut, J. Benjamin; Robert, Jason Scott

2012-01-01

These are interesting days in the scientific, social, and political debates about human embryonic stem cell research. Pluripotent stem cells--cells that can, in principle, give rise to the body's full range of cell types--were previously derivable only from human embryos that were destroyed in the process. Now, a variety of somatic cell types can…

Law No. 711 on fertilization outside the human body, 14 June 1988.

PubMed

1988-01-01

This Swedish Law reads as follows: "Section 1: this Law shall apply to the fertilization of a woman's egg outside her body, for the purpose of producing a child. Section 2: an egg which has been fertilized outside the body of a woman may not be introduced into her body unless: 1) the woman is married or living in a state of cohabitation; 2) the husband or cohabitant gives his written consent; and 3) the egg is the woman's own and has been fertilized with the sperm of her husband or cohabitant. Section 3: unless the authorization of the National Board of Health and Welfare is obtained, fertilization outside the human body may only be carried out in a general hospital. Section 4: persons committing a breach of Section 2 or 3 habitually or for gain shall be liable to a fine or to a prison sentence not exceeding six months." full text

Simplified model of mean double step (MDS) in human body movement

NASA Astrophysics Data System (ADS)

Dusza, Jacek J.; Wawrzyniak, Zbigniew M.; Mugarra González, C. Fernando

In this paper we present a simplified and useful model of the human body movement based on the full gait cycle description, called the Mean Double Step (MDS). It enables the parameterization and simplification of the human movement. Furthermore it allows a description of the gait cycle by providing standardized estimators to transform the gait cycle into a periodical movement process. Moreover the method of simplifying the MDS model and its compression are demonstrated. The simplification is achieved by reducing the number of bars of the spectrum and I or by reducing the number of samples describing the MDS both in terms of reducing their computational burden and their resources for the data storage. Our MDS model, which is applicable to the gait cycle method for examining patients, is non-invasive and provides the additional advantage of featuring a functional characterization of the relative or absolute movement of any part of the body.

Full Body Loading for Small Exercise Devices Project

NASA Technical Reports Server (NTRS)

Downs, Meghan; Hanson, Andrea; Newby, Nathaniel

2015-01-01

Protecting astronauts' spine, hip, and lower body musculoskeletal strength will be critical to safely and efficiently perform physically demanding vehicle egress, exploration, and habitat building activities necessary to expand human presence in the solar system. Functionally limiting decrements in musculoskeletal health are likely during Mars proving-ground and Earth-independent missions given extended transit times and the vehicle limitations for exercise devices (low-mass, small volume). Most small exercise device concepts are designed with single-cable loading, which inhibits the ability to perform full body exercises requiring two-point loading at the shoulders. Shoulder loading is critical to protect spine, hip, and lower body musculoskeletal strength. We propose a novel low-mass, low-maintenance, and rapid deploy pulley-based system that can attach to a single-cable small exercise device to enable two-point loading at the shoulders. This attachment could protect astronauts' health and save cost, space, and energy during all phases of the Journey to Mars.

First Insights into the Diverse Human Archaeome: Specific Detection of Archaea in the Gastrointestinal Tract, Lung, and Nose and on Skin

PubMed Central

Koskinen, Kaisa; Pausan, Manuela R.; Perras, Alexandra K.; Beck, Michael; Bang, Corinna; Mora, Maximilian; Schilhabel, Anke; Schmitz, Ruth

2017-01-01

ABSTRACT Human-associated archaea remain understudied in the field of microbiome research, although in particular methanogenic archaea were found to be regular commensals of the human gut, where they represent keystone species in metabolic processes. Knowledge on the abundance and diversity of human-associated archaea is extremely limited, and little is known about their function(s), their overall role in human health, or their association with parts of the human body other than the gastrointestinal tract and oral cavity. Currently, methodological issues impede the full assessment of the human archaeome, as bacteria-targeting protocols are unsuitable for characterization of the full spectrum of Archaea. The goal of this study was to establish conservative protocols based on specifically archaea-targeting, PCR-based methods to retrieve first insights into the archaeomes of the human gastrointestinal tract, lung, nose, and skin. Detection of Archaea was highly dependent on primer selection and the sequence processing pipeline used. Our results enabled us to retrieve a novel picture of the human archaeome, as we found for the first time Methanobacterium and Woesearchaeota (DPANN superphylum) to be associated with the human gastrointestinal tract and the human lung, respectively. Similar to bacteria, human-associated archaeal communities were found to group biogeographically, forming (i) the thaumarchaeal skin landscape, (ii) the (methano)euryarchaeal gastrointestinal tract, (iii) a mixed skin-gastrointestinal tract landscape for the nose, and (iv) a woesearchaeal lung landscape. On the basis of the protocols we used, we were able to detect unexpectedly high diversity of archaea associated with different body parts. PMID:29138298

Social science at the wildland-urban interface: a compendium of research results to create fire-adapted communities

Treesearch

Eric Toman; Melanie Stidham; Sarah McCaffrey; Bruce Shindler

2013-01-01

Over the past decade, a growing body of research has been conducted on the human dimensions of wildland fire. As this research has matured, there has been a recognition of the need to examine the full body of resulting literature to synthesize disparate findings and identify lessons learned across studies. These lessons can then be applied to fostering fire-adapted...

Bayesian inference of physiologically meaningful parameters from body sway measurements.

PubMed

Tietäväinen, A; Gutmann, M U; Keski-Vakkuri, E; Corander, J; Hæggström, E

2017-06-19

The control of the human body sway by the central nervous system, muscles, and conscious brain is of interest since body sway carries information about the physiological status of a person. Several models have been proposed to describe body sway in an upright standing position, however, due to the statistical intractability of the more realistic models, no formal parameter inference has previously been conducted and the expressive power of such models for real human subjects remains unknown. Using the latest advances in Bayesian statistical inference for intractable models, we fitted a nonlinear control model to posturographic measurements, and we showed that it can accurately predict the sway characteristics of both simulated and real subjects. Our method provides a full statistical characterization of the uncertainty related to all model parameters as quantified by posterior probability density functions, which is useful for comparisons across subjects and test settings. The ability to infer intractable control models from sensor data opens new possibilities for monitoring and predicting body status in health applications.

Expanded opportunities of THz passive camera for the detection of concealed objects

NASA Astrophysics Data System (ADS)

Trofimov, Vyacheslav A.; Trofimov, Vladislav V.; Kuchik, Igor E.

2013-10-01

Among the security problems, the detection of object implanted into either the human body or animal body is the urgent problem. At the present time the main tool for the detection of such object is X-raying only. However, X-ray is the ionized radiation and therefore can not be used often. Other way for the problem solving is passive THz imaging using. In our opinion, using of the passive THz camera may help to detect the object implanted into the human body under certain conditions. The physical reason of such possibility arises from temperature trace on the human skin as a result of the difference in temperature between object and parts of human body. Modern passive THz cameras have not enough resolution in temperature to see this difference. That is why, we use computer processing to enhance the passive THz camera resolution for this application. After computer processing of images captured by passive THz camera TS4, developed by ThruVision Systems Ltd., we may see the pronounced temperature trace on the human body skin from the water, which is drunk by person, or other food eaten by person. Nevertheless, there are many difficulties on the way of full soution of this problem. We illustrate also an improvement of quality of the image captured by comercially available passive THz cameras using computer processing. In some cases, one can fully supress a noise on the image without loss of its quality. Using computer processing of the THz image of objects concealed on the human body, one may improve it many times. Consequently, the instrumental resolution of such device may be increased without any additional engineering efforts.

Brain-machine interfacing control of whole-body humanoid motion

PubMed Central

Bouyarmane, Karim; Vaillant, Joris; Sugimoto, Norikazu; Keith, François; Furukawa, Jun-ichiro; Morimoto, Jun

2014-01-01

We propose to tackle in this paper the problem of controlling whole-body humanoid robot behavior through non-invasive brain-machine interfacing (BMI), motivated by the perspective of mapping human motor control strategies to human-like mechanical avatar. Our solution is based on the adequate reduction of the controllable dimensionality of a high-DOF humanoid motion in line with the state-of-the-art possibilities of non-invasive BMI technologies, leaving the complement subspace part of the motion to be planned and executed by an autonomous humanoid whole-body motion planning and control framework. The results are shown in full physics-based simulation of a 36-degree-of-freedom humanoid motion controlled by a user through EEG-extracted brain signals generated with motor imagery task. PMID:25140134

Property and the body: Applying Honoré

PubMed Central

Quigley, Muireann

2007-01-01

This paper argues that the new commercial and quasi‐commercial activities of medicine, scientists, pharmaceutical companies and industry with regard to human tissue has given rise to a whole new way of valuing our bodies. It is argued that a property framework may be an effective and constructive method of exploring issues arising from this. The paper refers to A M Honoré's theory of ownership and aims to show that we have full liberal ownership of our own bodies and as such can be considered to be self‐owners. PMID:17971463

The effect of added fullness and ventilation holes in T-shirt design on thermal comfort.

PubMed

Ho, Chupo; Fan, Jintu; Newton, Edward; Au, Raymond

2011-04-01

This paper reports on an experimental investigation on the effect of added fullness and ventilation holes in T-shirt design on clothing comfort measured in terms of thermal insulation and moisture vapour resistance. Four T-shirts in four different sizes (S, M, L, XL) were cut under the traditional sizing method while another (F-1) was cut with specially added fullness to create a 'flared' drape. A thermal manikin 'Walter' was used to measure the thermal insulation and moisture vapour resistance of the T-shirts in a chamber with controlled temperature, relative humidity and air velocity. The tests included four conditions: manikin standing still in the no-wind and windy conditions and walking in the no-wind and windy condition. It was found that adding fullness in the T-shirt design (F-1) to create the 'flared' drape can significantly reduce the T-shirt's thermal insulation and moisture vapour resistance under walking or windy conditions. Heat and moisture transmission through the T-shirt can be further enhanced by creating small apertures on the front and back of the T-shirt with specially added fullness. STATEMENT OF RELEVANCE: The thermal comfort of the human body is one of the key issues in the study of ergonomics. When doing exercise, a human body will generate heat, which will eventually result in sweating. If heat and moisture are not released effectively from the body, heat stress may occur and the person's performance will be negatively affected. Therefore, contemporary athletic T-shirts are designed to improve the heat and moisture transfer from the wearer. Through special cutting, such athletic T-shirts can be designed to improve the ventilation of the wearer.

Does affective touch influence the virtual reality full body illusion?

PubMed

de Jong, Jutta R; Keizer, Anouk; Engel, Manja M; Dijkerman, H Chris

2017-06-01

The sense of how we experience our physical body as our own represents a fundamental component of human self-awareness. Body ownership can be studied with bodily illusions which are generated by inducing a visuo-tactile conflict where individuals experience illusionary ownership over a fake body or body part, such as a rubber hand. Previous studies showed that different types of touch modulate the strength of experienced ownership over a rubber hand. Specifically, participants experienced more ownership after the rubber hand illusion was induced through affective touch vs non-affective touch. It is, however, unclear whether this effect would also occur for an entire fake body. The aim of this study was, therefore, to investigate whether affective touch modulates the strength of ownership in a virtual reality full body illusion. To elicit this illusion, we used slow (3 cm/s; affective touch) and fast (30 cm/s; non-affective touch) stroking velocities on the participants' abdomen. Both stroking velocities were performed either synchronous or asynchronous (control condition), while participants viewed a virtual body from a first-person-perspective. In our first study, we found that participants experienced more subjective ownership over a virtual body in the affective touch condition, compared to the non-affective touch condition. In our second study, we found higher levels of subjective ownership for synchronous stimulation, compared to asynchronous, for both touch conditions, but failed to replicate the findings from study 1 that show a difference between affective and non-affective touch. We, therefore, cannot conclude unequivocally that affective touch enhances the full-body illusion. Future research is required to study the effects of affective touch on body ownership.

Battery-free, wireless sensors for full-body pressure and temperature mapping

PubMed Central

Han, Seungyong; Kim, Jeonghyun; Won, Sang Min; Ma, Yinji; Kang, Daeshik; Xie, Zhaoqian; Lee, Kyu-Tae; Chung, Ha Uk; Banks, Anthony; Min, Seunghwan; Heo, Seung Yun; Davies, Charles R.; Lee, Jung Woo; Lee, Chi-Hwan; Kim, Bong Hoon; Li, Kan; Zhou, Yadong; Wei, Chen; Feng, Xue; Huang, Yonggang; Rogers, John A.

2018-01-01

Thin, soft, skin-like sensors capable of precise, continuous measurements of physiological health have broad potential relevance to clinical health care. Use of sensors distributed over a wide area for full-body, spatiotemporal mapping of physiological processes would be a considerable advance for this field. We introduce materials, device designs, wireless power delivery and communication strategies, and overall system architectures for skin-like, battery-free sensors of temperature and pressure that can be used across the entire body. Combined experimental and theoretical investigations of the sensor operation and the modes for wireless addressing define the key features of these systems. Studies with human subjects in clinical sleep laboratories and in adjustable hospital beds demonstrate functionality of the sensors, with potential implications for monitoring of circadian cycles and mitigating risks for pressure-induced skin ulcers. PMID:29618561

A research on the postural stability of a person wearing the lower limb exoskeletal robot by the HAT model.

PubMed

Chang, Minsu; Kim, Yeongmin; Lee, Yoseph; Jeon, Doyoung

2017-07-01

This paper proposes a method of detecting the postural stability of a person wearing the lower limb exoskeletal robot with the HAT(Head-Arm-Trunk) model. Previous studies have shown that the human posture is stable when the CoM(Center of Mass) of the human body is placed on the BoS(Base of Support). In the case of the lower limb exoskeletal robot, the motion data, which are used for the CoM estimation, are acquired by sensors in the robot. The upper body, however, does not have sensors in each segment so that it may cause the error of the CoM estimation. In this paper, the HAT(Head-Arm-Trunk) model which combines head, arms, and torso into a single segment is considered because the motion of head and arms are unknown due to the lack of sensors. To verify the feasibility of HAT model, the reflecting markers are attached to each segment of the whole human body and the exact motion data are acquired by the VICON to compare the COM of the full body model and HAT model. The difference between the CoM with full body and that with HAT model is within 20mm for the various motions of head and arms. Based on the HAT model, the XCoM(Extrapolated Center of Mass) which includes the velocity of the CoM is used for prediction of the postural stability. The experiment of making unstable posture shows that the XCoM of the whole body based on the HAT model is feasible to detect the instance of postural instability earlier than the CoM by 20-250 msec. This result may be used for the lower limb exoskeletal robot to prepare for any action to prevent the falling down.

Performances of the PIPER scalable child human body model in accident reconstruction

PubMed Central

Giordano, Chiara; Kleiven, Svein

2017-01-01

Human body models (HBMs) have the potential to provide significant insights into the pediatric response to impact. This study describes a scalable/posable approach to perform child accident reconstructions using the Position and Personalize Advanced Human Body Models for Injury Prediction (PIPER) scalable child HBM of different ages and in different positions obtained by the PIPER tool. Overall, the PIPER scalable child HBM managed reasonably well to predict the injury severity and location of the children involved in real-life crash scenarios documented in the medical records. The developed methodology and workflow is essential for future work to determine child injury tolerances based on the full Child Advanced Safety Project for European Roads (CASPER) accident reconstruction database. With the workflow presented in this study, the open-source PIPER scalable HBM combined with the PIPER tool is also foreseen to have implications for improved safety designs for a better protection of children in traffic accidents. PMID:29135997

A matter of life and death: knowledge about the body and concept of death in adults with intellectual disabilities.

PubMed

McEvoy, J; Treacy, B; Quigley, J

2017-01-01

An increased awareness of how people with intellectual disabilities (ID) understand death and dying is necessary in supporting life-long learning, post-bereavement support and planning end-of-life care. Previous research suggests that adults with ID have a limited or 'patchy' understanding of the basic biological components of death. However, the relationship between biological understanding of how the body works and conceptualisation of death remains unexplored in this population. Thirty adults with ID were interviewed to assess their knowledge of human body function and their understanding of the concept of death. Using pictures, participants were asked if they recognised certain organs, asked to explain the function of various body parts and what would happen if certain body parts were missing or did not work. Participants who referred to 'life' or 'not dying' as the goal of body function were categorised as 'Life Theorisers'. In addition, participants were asked about the causes of death, whether all things die and the status of the body after death. The results support previous studies suggesting that understanding of death in adults with ID varies from partial to full comprehension and is associated with level of ID. Also, death comprehension was positively correlated with total body interview scores and 'Life Theorisers' who understood that body parts maintain life and who spontaneously appealed to 'vitalistic' concepts when reasoning about the human body were also more sophisticated in their understanding of death. The study highlights the relationship between knowledge about the goal of human body functioning and death comprehension in adults with ID. The potential that learning to adopt a 'vitalistic' approach to human functioning may have on the acquisition of a greater understanding of death and dying, understanding illness and supporting end-of-life planning is discussed. © 2016 MENCAP and International Association of the Scientific Study of Intellectual and Developmental Disabilities and John Wiley & Sons Ltd.

One-step affinity tag purification of full-length recombinant human AP-1 complexes from bacterial inclusion bodies using a polycistronic expression system

PubMed Central

Wang, Wei-Ming; Lee, A-Young; Chiang, Cheng-Ming

2008-01-01

The AP-1 transcription factor is a dimeric protein complex formed primarily between Jun (c-Jun, JunB, JunD) and Fos (c-Fos, FosB, Fra-1, Fra-2) family members. These distinct AP-1 complexes are expressed in many cell types and modulate target gene expression implicated in cell proliferation, differentiation, and stress responses. Although the importance of AP-1 has long been recognized, the biochemical characterization of AP-1 remains limited in part due to the difficulty in purifying full-length, reconstituted dimers with active DNA-binding and transcriptional activity. Using a combination of bacterial coexpression and epitope-tagging methods, we successfully purified all 12 heterodimers (3 Jun × 4 Fos) of full-length human AP-1 complexes as well as c-Jun/c-Jun, JunD/JunD, and c-Jun/JunD dimers from bacterial inclusion bodies using one-step nickel-NTA affinity tag purification following denaturation and renaturation of coexpressed AP-1 subunits. Coexpression of two constitutive components in a dimeric AP-1 complex helps stabilize the proteins when compared with individual protein expression in bacteria. Purified dimeric AP-1 complexes are functional in sequence-specific DNA binding, as illustrated by electrophoretic mobility shift assays and DNase I footprinting, and are also active in transcription with in vitro-reconstituted human papillomavirus (HPV) chromatin containing AP-1-binding sites in the native configuration of HPV nucleosomes. The availability of these recombinant full-length human AP-1 complexes has greatly facilitated mechanistic studies of AP-1-regulated gene transcription in many biological systems. PMID:18329890

Cardiovascular function and basics of physiology in microgravity.

PubMed

Aubert, André E; Beckers, Frank; Verheyden, Bart

2005-04-01

Space exploration is a dream of mankind. However, this intriguing environment is not without risks. Life, and the human body, has developed all over evolution in the constant presence of gravity, especially from the moment on when living creatures left the ocean. When this gravitational force is no longer acting on the body, drastic changes occur. Some of these changes occur immediately, others progress only slowly. In the past 40 years of human space flight (first orbital flight by Yuri Gagarin on 12 April, 1961) several hazards for the human body have been identified. Bone mineral density is lost, muscle atrophy and cardiovascular deconditioning occur; pulmonary function, fluid regulating systems of the body, the sensory and the balance system are all disturbed by the lack of gravity. These changes in human physiology have to be reversed again when astronauts return to earth. This can cause adaptation problems, especially after long-duration space flights. Also the reaction of human physiology to radiation in space poses a huge risk at this moment. In this review the accent will be on cardiovascular function in space: how normal function is modified to reach a new equilibrium in space after short- and long-duration exposure to microgravity. In order to make long-duration space flight possible the mechanisms of this physiological adaptation must be understood to full extent. Only with this knowledge, effective countermeasures can be developed.

Digital evaluation of sitting posture comfort in human-vehicle system under Industry 4.0 framework

NASA Astrophysics Data System (ADS)

Tao, Qing; Kang, Jinsheng; Sun, Wenlei; Li, Zhaobo; Huo, Xiao

2016-09-01

Most of the previous studies on the vibration ride comfort of the human-vehicle system were focused only on one or two aspects of the investigation. A hybrid approach which integrates all kinds of investigation methods in real environment and virtual environment is described. The real experimental environment includes the WBV(whole body vibration) test, questionnaires for human subjective sensation and motion capture. The virtual experimental environment includes the theoretical calculation on simplified 5-DOF human body vibration model, the vibration simulation and analysis within ADAMS/VibrationTM module, and the digital human biomechanics and occupational health analysis in Jack software. While the real experimental environment provides realistic and accurate test results, it also serves as core and validation for the virtual experimental environment. The virtual experimental environment takes full advantages of current available vibration simulation and digital human modelling software, and makes it possible to evaluate the sitting posture comfort in a human-vehicle system with various human anthropometric parameters. How this digital evaluation system for car seat comfort design is fitted in the Industry 4.0 framework is also proposed.

A journey toward wholeness, a journey to God: physical fitness as embodied spirituality.

PubMed

Greenwood, Tracey C; Delgado, Teresa

2013-09-01

Physical fitness expressed through exercise can be, if done with the right intention, a form of spiritual discipline that reflects the relational love of humanity to God as well as an expression of a healthy love of the embodied self. Through an analysis of the physiological benefits of exercise science applied to the human body, this paper will demonstrate how such attention to the optimal physical fitness of the body, including weight and cardiovascular training and nutrition, is an affirmation of three foundational theological principles of human embodiment: as created in the "imago Dei", as unified body/spirit, and as part of God's creation calling for proper stewardship. In a contemporary climate where women's bodies in particular are viewed through the lens of commodification-as visual objects for sale based on prescribed notions of superficial esthetics and beauty-as well as the consistently high rates of eating disorders such as anorexia, bulimia, and obesity, authors Greenwood and Delgado offer a vision of how women and men can imagine a subjective relationship with their own bodies that reflects the abundant love of God for God's creation. Spoken from the lived experience of professional fitness competitor and trainer, as well as trained biokineticist, Dr. Greenwood presents the most current scientific data in the field of biokinetics that grounds the theological analysis offered by Dr. Delgado, whose personal journey through anorexia and scholarly emphasis on Christian theological anthropology inform this work. Taken together, Greenwood and Delgado suggest a response to God's love for humanity, including our physical bodily humanity, which entails a responsibility to attend to the physical fitness of our bodies in order to live into the fullness, flourishing and love of God's creation as God intended.

Punch Response of Gels at Different Loading Rates

DTIC Science & Technology

2014-03-01

calibration (4, 6). While similar in density, neither clay nor gelatin simulates the tissue structure of the human body accurately. Danelson et al. (7...the load response of human tissue. 2 Recent work on gelatins has shown promise in robotics, sensors, and microfluidics (9). Hydrogels ( water -based...images of a high-contrast, random pattern of speckles and a sophisticated optimization program to measure full-field deformation. Figure 1 shows an

Integrated Analytic and Linearized Inverse Kinematics for Precise Full Body Interactions

NASA Astrophysics Data System (ADS)

Boulic, Ronan; Raunhardt, Daniel

Despite the large success of games grounded on movement-based interactions the current state of full body motion capture technologies still prevents the exploitation of precise interactions with complex environments. This paper focuses on ensuring a precise spatial correspondence between the user and the avatar. We build upon our past effort in human postural control with a Prioritized Inverse Kinematics framework. One of its key advantage is to ease the dynamic combination of postural and collision avoidance constraints. However its reliance on a linearized approximation of the problem makes it vulnerable to the well-known full extension singularity of the limbs. In such context the tracking performance is reduced and/or less believable intermediate postural solutions are produced. We address this issue by introducing a new type of analytic constraint that smoothly integrates within the prioritized Inverse Kinematics framework. The paper first recalls the background of full body 3D interactions and the advantages and drawbacks of the linearized IK solution. Then the Flexion-EXTension constraint (FLEXT in short) is introduced for the partial position control of limb-like articulated structures. Comparative results illustrate the interest of this new type of integrated analytical and linearized IK control.

Human growth and body weight dynamics: an integrative systems model.

PubMed

Rahmandad, Hazhir

2014-01-01

Quantifying human weight and height dynamics due to growth, aging, and energy balance can inform clinical practice and policy analysis. This paper presents the first mechanism-based model spanning full individual life and capturing changes in body weight, composition and height. Integrating previous empirical and modeling findings and validated against several additional empirical studies, the model replicates key trends in human growth including A) Changes in energy requirements from birth to old ages. B) Short and long-term dynamics of body weight and composition. C) Stunted growth with chronic malnutrition and potential for catch up growth. From obesity policy analysis to treating malnutrition and tracking growth trajectories, the model can address diverse policy questions. For example I find that even without further rise in obesity, the gap between healthy and actual Body Mass Indexes (BMIs) has embedded, for different population groups, a surplus of 14%-24% in energy intake which will be a source of significant inertia in obesity trends. In another analysis, energy deficit percentage needed to reduce BMI by one unit is found to be relatively constant across ages. Accompanying documented and freely available simulation model facilitates diverse applications customized to different sub-populations.

Human Growth and Body Weight Dynamics: An Integrative Systems Model

PubMed Central

Rahmandad, Hazhir

2014-01-01

Quantifying human weight and height dynamics due to growth, aging, and energy balance can inform clinical practice and policy analysis. This paper presents the first mechanism-based model spanning full individual life and capturing changes in body weight, composition and height. Integrating previous empirical and modeling findings and validated against several additional empirical studies, the model replicates key trends in human growth including A) Changes in energy requirements from birth to old ages. B) Short and long-term dynamics of body weight and composition. C) Stunted growth with chronic malnutrition and potential for catch up growth. From obesity policy analysis to treating malnutrition and tracking growth trajectories, the model can address diverse policy questions. For example I find that even without further rise in obesity, the gap between healthy and actual Body Mass Indexes (BMIs) has embedded, for different population groups, a surplus of 14%–24% in energy intake which will be a source of significant inertia in obesity trends. In another analysis, energy deficit percentage needed to reduce BMI by one unit is found to be relatively constant across ages. Accompanying documented and freely available simulation model facilitates diverse applications customized to different sub-populations. PMID:25479101

Full-Body Musculoskeletal Model for Muscle-Driven Simulation of Human Gait.

PubMed

Rajagopal, Apoorva; Dembia, Christopher L; DeMers, Matthew S; Delp, Denny D; Hicks, Jennifer L; Delp, Scott L

2016-10-01

Musculoskeletal models provide a non-invasive means to study human movement and predict the effects of interventions on gait. Our goal was to create an open-source 3-D musculoskeletal model with high-fidelity representations of the lower limb musculature of healthy young individuals that can be used to generate accurate simulations of gait. Our model includes bony geometry for the full body, 37 degrees of freedom to define joint kinematics, Hill-type models of 80 muscle-tendon units actuating the lower limbs, and 17 ideal torque actuators driving the upper body. The model's musculotendon parameters are derived from previous anatomical measurements of 21 cadaver specimens and magnetic resonance images of 24 young healthy subjects. We tested the model by evaluating its computational time and accuracy of simulations of healthy walking and running. Generating muscle-driven simulations of normal walking and running took approximately 10 minutes on a typical desktop computer. The differences between our muscle-generated and inverse dynamics joint moments were within 3% (RMSE) of the peak inverse dynamics joint moments in both walking and running, and our simulated muscle activity showed qualitative agreement with salient features from experimental electromyography data. These results suggest that our model is suitable for generating muscle-driven simulations of healthy gait. We encourage other researchers to further validate and apply the model to study other motions of the lower extremity. The model is implemented in the open-source software platform OpenSim. The model and data used to create and test the simulations are freely available at https://simtk.org/home/full_body/, allowing others to reproduce these results and create their own simulations.

Full body musculoskeletal model for muscle-driven simulation of human gait

PubMed Central

Rajagopal, Apoorva; Dembia, Christopher L.; DeMers, Matthew S.; Delp, Denny D.; Hicks, Jennifer L.; Delp, Scott L.

2017-01-01

Objective Musculoskeletal models provide a non-invasive means to study human movement and predict the effects of interventions on gait. Our goal was to create an open-source, three-dimensional musculoskeletal model with high-fidelity representations of the lower limb musculature of healthy young individuals that can be used to generate accurate simulations of gait. Methods Our model includes bony geometry for the full body, 37 degrees of freedom to define joint kinematics, Hill-type models of 80 muscle-tendon units actuating the lower limbs, and 17 ideal torque actuators driving the upper body. The model’s musculotendon parameters are derived from previous anatomical measurements of 21 cadaver specimens and magnetic resonance images of 24 young healthy subjects. We tested the model by evaluating its computational time and accuracy of simulations of healthy walking and running. Results Generating muscle-driven simulations of normal walking and running took approximately 10 minutes on a typical desktop computer. The differences between our muscle-generated and inverse dynamics joint moments were within 3% (RMSE) of the peak inverse dynamics joint moments in both walking and running, and our simulated muscle activity showed qualitative agreement with salient features from experimental electromyography data. Conclusion These results suggest that our model is suitable for generating muscle-driven simulations of healthy gait. We encourage other researchers to further validate and apply the model to study other motions of the lower-extremity. Significance The model is implemented in the open source software platform OpenSim. The model and data used to create and test the simulations are freely available at https://simtk.org/home/full_body/, allowing others to reproduce these results and create their own simulations. PMID:27392337

Impact response and biomechanical analysis of the knee-thigh-hip complex in frontal impacts with a full human body finite element model.

PubMed

Ruan, Jesse S; El-Jawahri, Raed; Barbat, Saeed; Rouhana, Stephen W; Prasad, Priya

2008-11-01

Changes in vehicle safety design technology and the increasing use of seat-belts and airbag restraint systems have gradually changed the relative proportion of lower extremity injuries. These changes in real world injuries have renewed interest and the need of further investigation into occupant injury mechanisms and biomechanical impact responses of the knee-thigh-hip complex during frontal impacts. This study uses a detailed finite element model of the human body to simulate occupant knee impacts experienced in frontal crashes. The human body model includes detailed anatomical features of the head, neck, shoulder, chest, thoracic and lumbar spine, abdomen, pelvis, and lower and upper extremities. The material properties used in the model for each anatomic part of the human body were obtained from test data reported in the literature. The human body model used in the current study has been previously validated in frontal and side impacts. It was further validated with cadaver knee-thigh-hip impact tests in the current study. The effects of impactor configuration and flexion angle of the knee on biomechanical impact responses of the knee-thigh-hip complex were studied using the validated human body finite element model. This study showed that the knee flexion angle and the impact direction and shape of the impactors affected the injury outcomes of the knee-thigh-hip complex significantly. The 60 degrees flexed knee impact showed the least impact force, knee pressure, femoral von Mises stress, and pelvic von Mises stress but largest relative displacements of the Posterior Cruciate Ligament (PCL) and Anterior Cruciate Ligament (ACL). The 90 degrees flexed knee impact resulted in a higher impact force, knee pressure, femoral von Mises stress, and pelvic von Mises stress; but smaller PCL and ACL displacements. Stress distributions of the patella, femur, and pelvis were also given for all the simulated conditions.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Asadi, Somayeh; Masoudi, Seyed Farhad, E-mail: masoudi@kntu.ac.ir; Shahriari, Majid

In ophthalmic brachytherapy dosimetry, it is common to consider the water phantom as human eye anatomy. However, for better clinical analysis, there is a need for the dose determination in different parts of the eye. In this work, a full human eye is simulated with MCNP-4C code by considering all parts of the eye, i.e., the lens, cornea, retina, choroid, sclera, anterior chamber, optic nerve, and bulk of the eye comprising vitreous body and tumor. The average dose in different parts of this full model of the human eye is determined and the results are compared with the dose calculatedmore » in water phantom. The central axes depth dose and the dose in whole of the tumor for these 2 simulated eye models are calculated as well, and the results are compared.« less

Cell lineage distribution atlas of the human stomach reveals heterogeneous gland populations in the gastric antrum

PubMed Central

Choi, Eunyoung; Roland, Joseph T.; Barlow, Brittney J.; O’Neal, Ryan; Rich, Amy E.; Nam, Ki Taek; Shi, Chanjuan; Goldenring, James R.

2014-01-01

Objective The glands of the stomach body and antral mucosa contain a complex compendium of cell lineages. In lower mammals, the distribution of oxyntic glands and antral glands define the anatomical regions within the stomach. We examined in detail the distribution of the full range of cell lineages within the human stomach. Design We determined the distribution of gastric gland cell lineages with specific immunocytochemical markers in entire stomach specimens from three non-obese organ donors. Results The anatomical body and antrum of the human stomach were defined by the presence of ghrelin and gastrin cells, respectively. Concentrations of somatostatin cells were observed in the proximal stomach. Parietal cells were seen in all glands of the body of stomach as well as in over 50% of antral glands. MIST1-expressing chief cells were predominantly observed in the body, although individual glands of the antrum also showed MIST1-expressing chief cells. While classically-described antral glands were observed with gastrin cells and deep antral mucous cells without any parietal cells, we also observed a substantial population of mixed-type glands containing both parietal cells and G cells throughout the antrum. Conclusions Enteroendocrine cells show distinct patterns of localization in the human stomach. The existence of antral glands with mixed cell lineages indicates that human antral glands may be functionally chimeric with glands assembled from multiple distinct stem cell populations. PMID:24488499

Tele-operated search robot for human detection using histogram of oriented objects

NASA Astrophysics Data System (ADS)

Cruz, Febus Reidj G.; Avendaño, Glenn O.; Manlises, Cyrel O.; Avellanosa, James Jason G.; Abina, Jyacinth Camille F.; Masaquel, Albert M.; Siapno, Michael Lance O.; Chung, Wen-Yaw

2017-02-01

Disasters such as typhoons, tornadoes, and earthquakes are inevitable. Aftermaths of these disasters include the missing people. Using robots with human detection capabilities to locate the missing people, can dramatically reduce the harm and risk to those who work in such circumstances. This study aims to: design and build a tele-operated robot; implement in MATLAB an algorithm for the detection of humans; and create a database of human identification based on various positions, angles, light intensity, as well as distances from which humans will be identified. Different light intensities were made by using Photoshop to simulate smoke, dust and water drops conditions. After processing the image, the system can indicate either a human is detected or not detected. Testing with bodies covered was also conducted to test the algorithm's robustness. Based on the results, the algorithm can detect humans with full body shown. For upright and lying positions, detection can happen from 8 feet to 20 feet. For sitting position, detection can happen from 2 feet to 20 feet with slight variances in results because of different lighting conditions. The distances greater than 20 feet, no humans can be processed or false negatives can occur. For bodies covered, the algorithm can detect humans in cases made under given circumstances. On three positions, humans can be detected from 0 degrees to 180 degrees under normal, with smoke, with dust, and with water droplet conditions. This study was able to design and build a tele-operated robot with MATLAB algorithm that can detect humans with an overall precision of 88.30%, from which a database was created for human identification based on various conditions, where humans will be identified.

Human-Derived Disturbance Estimation and Compensation (DEC) Method Lends Itself to a Modular Sensorimotor Control in a Humanoid Robot.

PubMed

Lippi, Vittorio; Mergner, Thomas

2017-01-01

The high complexity of the human posture and movement control system represents challenges for diagnosis, therapy, and rehabilitation of neurological patients. We envisage that engineering-inspired, model-based approaches will help to deal with the high complexity of the human posture control system. Since the methods of system identification and parameter estimation are limited to systems with only a few DoF, our laboratory proposes a heuristic approach that step-by-step increases complexity when creating a hypothetical human-derived control systems in humanoid robots. This system is then compared with the human control in the same test bed, a posture control laboratory. The human-derived control builds upon the identified disturbance estimation and compensation (DEC) mechanism, whose main principle is to support execution of commanded poses or movements by compensating for external or self-produced disturbances such as gravity effects. In previous robotic implementation, up to 3 interconnected DEC control modules were used in modular control architectures separately for the sagittal plane or the frontal body plane and successfully passed balancing and movement tests. In this study we hypothesized that conflict-free movement coordination between the robot's sagittal and frontal body planes emerges simply from the physical embodiment, not necessarily requiring a full body control. Experiments were performed in the 14 DoF robot Lucy Posturob (i) demonstrating that the mechanical coupling from the robot's body suffices to coordinate the controls in the two planes when the robot produces movements and balancing responses in the intermediate plane, (ii) providing quantitative characterization of the interaction dynamics between body planes including frequency response functions (FRFs), as they are used in human postural control analysis, and (iii) witnessing postural and control stability when all DoFs are challenged together with the emergence of inter-segmental coordination in squatting movements. These findings represent an important step toward controlling in the robot in future more complex sensorimotor functions such as walking.

Human-Derived Disturbance Estimation and Compensation (DEC) Method Lends Itself to a Modular Sensorimotor Control in a Humanoid Robot

PubMed Central

Lippi, Vittorio; Mergner, Thomas

2017-01-01

The high complexity of the human posture and movement control system represents challenges for diagnosis, therapy, and rehabilitation of neurological patients. We envisage that engineering-inspired, model-based approaches will help to deal with the high complexity of the human posture control system. Since the methods of system identification and parameter estimation are limited to systems with only a few DoF, our laboratory proposes a heuristic approach that step-by-step increases complexity when creating a hypothetical human-derived control systems in humanoid robots. This system is then compared with the human control in the same test bed, a posture control laboratory. The human-derived control builds upon the identified disturbance estimation and compensation (DEC) mechanism, whose main principle is to support execution of commanded poses or movements by compensating for external or self-produced disturbances such as gravity effects. In previous robotic implementation, up to 3 interconnected DEC control modules were used in modular control architectures separately for the sagittal plane or the frontal body plane and successfully passed balancing and movement tests. In this study we hypothesized that conflict-free movement coordination between the robot's sagittal and frontal body planes emerges simply from the physical embodiment, not necessarily requiring a full body control. Experiments were performed in the 14 DoF robot Lucy Posturob (i) demonstrating that the mechanical coupling from the robot's body suffices to coordinate the controls in the two planes when the robot produces movements and balancing responses in the intermediate plane, (ii) providing quantitative characterization of the interaction dynamics between body planes including frequency response functions (FRFs), as they are used in human postural control analysis, and (iii) witnessing postural and control stability when all DoFs are challenged together with the emergence of inter-segmental coordination in squatting movements. These findings represent an important step toward controlling in the robot in future more complex sensorimotor functions such as walking. PMID:28951719

A new transcutaneous bidirectional communication for monitoring implanted artificial heart using the human body as a conductive medium.

PubMed

Okamoto, Eiji; Kato, Yoshikuni; Seino, Kazuyuki; Miura, Hidekazu; Shiraishi, Yasuyuki; Yambe, Tomoyuki; Mitamura, Yoshinori

2012-10-01

A transcutaneous communication system (TCS) is a key technology for monitoring and controlling artificial hearts and other artificial organs in the body. In this study, we developed a new TCS that uses the human body as a conductive medium. Direct data exchange provides a higher level of communication security compared to that of wireless methods without physical constraints such as an external wire. The external and internal units of the new TCS each consist mainly of a data transmitter and a data receiver. The data transmitter has an amplitude shift keying (ASK) modulator (carrier frequencies: 4 and 10 MHz) and an electrode. The ASK-modulated data current is led into the body through the electrode, and it flows back to the energy source through the body, the data receiver, and the earth ground that includes all conductors and dielectrics in the environment that are in close proximity to the patient. Performance of the TCS was evaluated by a communication test on the surface of the human body and in an animal experiment using a goat. The TCS was able to transmit data concurrently for 4 weeks between everywhere on the surface of the body and everywhere inside the body under full-duplex communication at a transmission rate of 115 kbps. The power consumption of each TCS unit was 125 mW with an ASK-modulated current of 7 mA (root-mean-square). While further study is required to secure its safety, the newly developed TCS has promise to be a next-generation transcutaneous communication device. © 2012, Copyright the Authors. Artificial Organs © 2012, International Center for Artificial Organs and Transplantation and Wiley Periodicals, Inc.

Dynamical simulation priors for human motion tracking.

PubMed

Vondrak, Marek; Sigal, Leonid; Jenkins, Odest Chadwicke

2013-01-01

We propose a simulation-based dynamical motion prior for tracking human motion from video in presence of physical ground-person interactions. Most tracking approaches to date have focused on efficient inference algorithms and/or learning of prior kinematic motion models; however, few can explicitly account for the physical plausibility of recovered motion. Here, we aim to recover physically plausible motion of a single articulated human subject. Toward this end, we propose a full-body 3D physical simulation-based prior that explicitly incorporates a model of human dynamics into the Bayesian filtering framework. We consider the motion of the subject to be generated by a feedback “control loop” in which Newtonian physics approximates the rigid-body motion dynamics of the human and the environment through the application and integration of interaction forces, motor forces, and gravity. Interaction forces prevent physically impossible hypotheses, enable more appropriate reactions to the environment (e.g., ground contacts), and are produced from detected human-environment collisions. Motor forces actuate the body, ensure that proposed pose transitions are physically feasible, and are generated using a motion controller. For efficient inference in the resulting high-dimensional state space, we utilize an exemplar-based control strategy that reduces the effective search space of motor forces. As a result, we are able to recover physically plausible motion of human subjects from monocular and multiview video. We show, both quantitatively and qualitatively, that our approach performs favorably with respect to Bayesian filtering methods with standard motion priors.

The Architectonic Experience of Body and Space in Augmented Interiors

PubMed Central

Pasqualini, Isabella; Blefari, Maria Laura; Tadi, Tej; Serino, Andrea; Blanke, Olaf

2018-01-01

The environment shapes our experience of space in constant interaction with the body. Architectonic interiors amplify the perception of space through the bodily senses; an effect also known as embodiment. The interaction of the bodily senses with the space surrounding the body can be tested experimentally through the manipulation of multisensory stimulation and measured via a range of behaviors related to bodily self-consciousness. Many studies have used Virtual Reality to show that visuotactile conflicts mediated via a virtual body or avatar can disrupt the unified subjective experience of the body and self. In the full-body illusion paradigm, participants feel as if the avatar was their body (ownership, self-identification) and they shift their center of awareness toward the position of the avatar (self-location). However, the influence of non-bodily spatial cues around the body on embodiment remains unclear, and data about the impact of architectonic space on human perception and self-conscious states are sparse. We placed participants into a Virtual Reality arena, where large and narrow virtual interiors were displayed with and without an avatar. We then applied synchronous or asynchronous visuotactile strokes to the back of the participants and avatar, or, to the front wall of the void interiors. During conditions of illusory self-identification with the avatar, participants reported sensations of containment, drift, and touch with the architectonic environment. The absence of the avatar suppressed such feelings, yet, in the large space, we found an effect of continuity between the physical and the virtual interior depending on the full-body illusion. We discuss subjective feelings evoked by architecture and compare the full-body illusion in augmented interiors to architectonic embodiment. A relevant outcome of this study is the potential to dissociate the egocentric, first-person view from the physical point of view through augmented architectonic space. PMID:29755378

The Architectonic Experience of Body and Space in Augmented Interiors.

PubMed

Pasqualini, Isabella; Blefari, Maria Laura; Tadi, Tej; Serino, Andrea; Blanke, Olaf

2018-01-01

The environment shapes our experience of space in constant interaction with the body. Architectonic interiors amplify the perception of space through the bodily senses; an effect also known as embodiment. The interaction of the bodily senses with the space surrounding the body can be tested experimentally through the manipulation of multisensory stimulation and measured via a range of behaviors related to bodily self-consciousness. Many studies have used Virtual Reality to show that visuotactile conflicts mediated via a virtual body or avatar can disrupt the unified subjective experience of the body and self. In the full-body illusion paradigm, participants feel as if the avatar was their body (ownership, self-identification) and they shift their center of awareness toward the position of the avatar (self-location). However, the influence of non-bodily spatial cues around the body on embodiment remains unclear, and data about the impact of architectonic space on human perception and self-conscious states are sparse. We placed participants into a Virtual Reality arena, where large and narrow virtual interiors were displayed with and without an avatar. We then applied synchronous or asynchronous visuotactile strokes to the back of the participants and avatar, or, to the front wall of the void interiors. During conditions of illusory self-identification with the avatar, participants reported sensations of containment, drift, and touch with the architectonic environment. The absence of the avatar suppressed such feelings, yet, in the large space, we found an effect of continuity between the physical and the virtual interior depending on the full-body illusion. We discuss subjective feelings evoked by architecture and compare the full-body illusion in augmented interiors to architectonic embodiment. A relevant outcome of this study is the potential to dissociate the egocentric, first-person view from the physical point of view through augmented architectonic space.

Deciding Access to Work-Integrated Learning: Human Resource Professionals as Gatekeepers

ERIC Educational Resources Information Center

Mackaway, Jacqueline; Winchester-Seeto, Theresa

2018-01-01

Universities, industry and professional bodies advocate work-integrated learning (WIL) as a valuable way to prepare graduates to meet the challenges of contemporary society. When organizations preference particular students over others to host on placement, the full individual and collective potential of WIL is not realized. This paper reports…

Cell lineage distribution atlas of the human stomach reveals heterogeneous gland populations in the gastric antrum.

PubMed

Choi, Eunyoung; Roland, Joseph T; Barlow, Brittney J; O'Neal, Ryan; Rich, Amy E; Nam, Ki Taek; Shi, Chanjuan; Goldenring, James R

2014-11-01

The glands of the stomach body and antral mucosa contain a complex compendium of cell lineages. In lower mammals, the distribution of oxyntic glands and antral glands define the anatomical regions within the stomach. We examined in detail the distribution of the full range of cell lineages within the human stomach. We determined the distribution of gastric gland cell lineages with specific immunocytochemical markers in entire stomach specimens from three non-obese organ donors. The anatomical body and antrum of the human stomach were defined by the presence of ghrelin and gastrin cells, respectively. Concentrations of somatostatin cells were observed in the proximal stomach. Parietal cells were seen in all glands of the body of the stomach as well as in over 50% of antral glands. MIST1 expressing chief cells were predominantly observed in the body although individual glands of the antrum also showed MIST1 expressing chief cells. While classically described antral glands were observed with gastrin cells and deep antral mucous cells without any parietal cells, we also observed a substantial population of mixed type glands containing both parietal cells and G cells throughout the antrum. Enteroendocrine cells show distinct patterns of localisation in the human stomach. The existence of antral glands with mixed cell lineages indicates that human antral glands may be functionally chimeric with glands assembled from multiple distinct stem cell populations. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Battery-free, wireless sensors for full-body pressure and temperature mapping.

PubMed

Han, Seungyong; Kim, Jeonghyun; Won, Sang Min; Ma, Yinji; Kang, Daeshik; Xie, Zhaoqian; Lee, Kyu-Tae; Chung, Ha Uk; Banks, Anthony; Min, Seunghwan; Heo, Seung Yun; Davies, Charles R; Lee, Jung Woo; Lee, Chi-Hwan; Kim, Bong Hoon; Li, Kan; Zhou, Yadong; Wei, Chen; Feng, Xue; Huang, Yonggang; Rogers, John A

2018-04-04

Thin, soft, skin-like sensors capable of precise, continuous measurements of physiological health have broad potential relevance to clinical health care. Use of sensors distributed over a wide area for full-body, spatiotemporal mapping of physiological processes would be a considerable advance for this field. We introduce materials, device designs, wireless power delivery and communication strategies, and overall system architectures for skin-like, battery-free sensors of temperature and pressure that can be used across the entire body. Combined experimental and theoretical investigations of the sensor operation and the modes for wireless addressing define the key features of these systems. Studies with human subjects in clinical sleep laboratories and in adjustable hospital beds demonstrate functionality of the sensors, with potential implications for monitoring of circadian cycles and mitigating risks for pressure-induced skin ulcers. Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

Dynamically adjustable foot-ground contact model to estimate ground reaction force during walking and running.

PubMed

Jung, Yihwan; Jung, Moonki; Ryu, Jiseon; Yoon, Sukhoon; Park, Sang-Kyoon; Koo, Seungbum

2016-03-01

Human dynamic models have been used to estimate joint kinetics during various activities. Kinetics estimation is in demand in sports and clinical applications where data on external forces, such as the ground reaction force (GRF), are not available. The purpose of this study was to estimate the GRF during gait by utilizing distance- and velocity-dependent force models between the foot and ground in an inverse-dynamics-based optimization. Ten males were tested as they walked at four different speeds on a force plate-embedded treadmill system. The full-GRF model whose foot-ground reaction elements were dynamically adjusted according to vertical displacement and anterior-posterior speed between the foot and ground was implemented in a full-body skeletal model. The model estimated the vertical and shear forces of the GRF from body kinematics. The shear-GRF model with dynamically adjustable shear reaction elements according to the input vertical force was also implemented in the foot of a full-body skeletal model. Shear forces of the GRF were estimated from body kinematics, vertical GRF, and center of pressure. The estimated full GRF had the lowest root mean square (RMS) errors at the slow walking speed (1.0m/s) with 4.2, 1.3, and 5.7% BW for anterior-posterior, medial-lateral, and vertical forces, respectively. The estimated shear forces were not significantly different between the full-GRF and shear-GRF models, but the RMS errors of the estimated knee joint kinetics were significantly lower for the shear-GRF model. Providing COP and vertical GRF with sensors, such as an insole-type pressure mat, can help estimate shear forces of the GRF and increase accuracy for estimation of joint kinetics. Copyright © 2016 Elsevier B.V. All rights reserved.

Human body contour data based activity recognition.

PubMed

Myagmarbayar, Nergui; Yuki, Yoshida; Imamoglu, Nevrez; Gonzalez, Jose; Otake, Mihoko; Yu, Wenwei

2013-01-01

This research work is aimed to develop autonomous bio-monitoring mobile robots, which are capable of tracking and measuring patients' motions, recognizing the patients' behavior based on observation data, and providing calling for medical personnel in emergency situations in home environment. The robots to be developed will bring about cost-effective, safe and easier at-home rehabilitation to most motor-function impaired patients (MIPs). In our previous research, a full framework was established towards this research goal. In this research, we aimed at improving the human activity recognition by using contour data of the tracked human subject extracted from the depth images as the signal source, instead of the lower limb joint angle data used in the previous research, which are more likely to be affected by the motion of the robot and human subjects. Several geometric parameters, such as, the ratio of height to weight of the tracked human subject, and distance (pixels) between centroid points of upper and lower parts of human body, were calculated from the contour data, and used as the features for the activity recognition. A Hidden Markov Model (HMM) is employed to classify different human activities from the features. Experimental results showed that the human activity recognition could be achieved with a high correct rate.

[Role of donor human milk feeding in preventing nosocomial infection in very low birth weight infants].

PubMed

Bi, Hong-Juan; Xu, Jing; Wei, Qiu-Fen

2018-02-01

To investigate the role of donor human milk in the prevention of nosocomial infection in very low birth weight infants. MeETHODS: A total of 105 hospitalized preterm infants with a very low birth weight were enrolled. They were classified into mother's own milk feeding group, donor human milk feeding group, and preterm formula feeding group, with 35 infants in each group. The three groups were compared in terms of incidence rates of nosocomial infection, necrotizing enterocolitis, and feeding intolerance, time to full enteral feeding, and early growth indices. Compared with the preterm formula feeding group, the donor human milk feeding group and the mother's own milk feeding group had significantly lower incidence rates of nosocomial infection and necrotizing enterocolitis and shorter time to full enteral feeding (P<0.05). There were no significant differences in head circumference, body length, and weight growth velocity among the three groups. Donor human milk can be used in case of a lack of mother's own milk and may help to reduce nosocomial infection.

Origins and early development of human body knowledge.

PubMed

Slaughter, Virginia; Heron, Michelle

2004-01-01

As a knowable object, the human body is highly complex. Evidence from several converging lines of research, including psychological studies, neuroimaging and clinical neuropsychology, indicates that human body knowledge is widely distributed in the adult brain, and is instantiated in at least three partially independent levels of representation. Sensorimotor body knowledge is responsible for on-line control and movement of one's own body and may also contribute to the perception of others' moving bodies; visuo-spatial body knowledge specifies detailed structural descriptions of the spatial attributes of the human body; and lexical-semantic body knowledge contains language-based knowledge about the human body. In the first chapter of this Monograph, we outline the evidence for these three hypothesized levels of human body knowledge, then review relevant literature on infants' and young children's human body knowledge in terms of the three-level framework. In Chapters II and III, we report two complimentary series of studies that specifically investigate the emergence of visuo-spatial body knowledge in infancy. Our technique is to compare infants'responses to typical and scrambled human bodies, in order to evaluate when and how infants acquire knowledge about the canonical spatial layout of the human body. Data from a series of visual habituation studies indicate that infants first discriminate scrambled from typical human body picture sat 15 to 18 months of age. Data from object examination studies similarly indicate that infants are sensitive to violations of three-dimensional human body stimuli starting at 15-18 months of age. The overall pattern of data supports several conclusions about the early development of human body knowledge: (a) detailed visuo-spatial knowledge about the human body is first evident in the second year of life, (b) visuo-spatial knowledge of human faces and human bodies are at least partially independent in infancy and (c) infants' initial visuo-spatial human body representations appear to be highly schematic, becoming more detailed and specific with development. In the final chapter, we explore these conclusions and discuss how levels of body knowledge may interact in early development.

Raman spectroscopic signature of vaginal fluid and its potential application in forensic body fluid identification.

PubMed

Sikirzhytskaya, Aliaksandra; Sikirzhytski, Vitali; Lednev, Igor K

2012-03-10

Traces of human body fluids, such as blood, saliva, sweat, semen and vaginal fluid, play an increasingly important role in forensic investigations. However, a nondestructive, easy and rapid identification of body fluid traces at the scene of a crime has not yet been developed. The obstacles have recently been addressed in our studies, which demonstrated the considerable potential of Raman spectroscopy. In this study, we continued to build a full library of body fluid spectroscopic signatures. The problems concerning vaginal fluid stain identification were addressed using Raman spectroscopy coupled with advanced statistical analysis. Calculated characteristic Raman and fluorescent spectral components were used to build a multidimensional spectroscopic signature of vaginal fluid, which demonstrated good specificity and was able to handle heterogeneous samples from different donors. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

Human Tolerance to Rapidly Applied Accelerations: A Summary of the Literature

NASA Technical Reports Server (NTRS)

Eiband, A. Martin

1959-01-01

The literature is surveyed to determine human tolerance to rapidly applied accelerations. Pertinent human and animal experiments applicable to space flight and to crash impact forces are analyzed and discussed. These data are compared and presented on the basis of a trapezoidal pulse. The effects of body restraint and of acceleration direction, onset rate, and plateau duration on the maximum tolerable and survivable rapidly applied accelerations are shown. Results of the survey indicate that adequate torso and extremity restraint is the primary variable in tolerance to rapidly applied accelerations. The harness, or restraint system, must be arranged to transmit the major portion of the accelerating force directly to the pelvic structure and not via the vertebral column. When the conditions of adequate restraint have been met, then the other variables, direction, magnitude, and onset rate of rapidly applied accelerations, govern maximum tolerance and injury limits. The results also indicate that adequately stressed aft-faced passenger seats offer maximum complete body support with minimum objectionable harnessing. Such a seat, whether designed for 20-, 30-, or 40-G dynamic loading, would include lap strap, chest (axillary) strap, and winged-back seat to increase headward and lateral G protection, full-height integral head rest, arm rests (load-bearing) with recessed hand-holds and provisions to prevent arms from slipping either laterally or beyond the seat back, and leg support to keep the legs from being wedged under the seat. For crew members and others whose duties require forward-facing seats, maximum complete body support requires lap, shoulder, and thigh straps, lap-belt tie-down strap, and full-height seat back with integral head support.

Whole body traveling wave magnetic resonance imaging at high field strength: homogeneity, efficiency, and energy deposition as compared with traditional excitation mechanisms.

PubMed

Zhang, Bei; Sodickson, Daniel K; Lattanzi, Riccardo; Duan, Qi; Stoeckel, Bernd; Wiggins, Graham C

2012-04-01

In 7 T traveling wave imaging, waveguide modes supported by the scanner radiofrequency shield are used to excite an MR signal in samples or tissue which may be several meters away from the antenna used to drive radiofrequency power into the system. To explore the potential merits of traveling wave excitation for whole-body imaging at 7 T, we compare numerical simulations of traveling wave and TEM systems, and juxtapose full-wave electrodynamic simulations using a human body model with in vivo human traveling wave imaging at multiple stations covering the entire body. The simulated and in vivo traveling wave results correspond well, with strong signal at the periphery of the body and weak signal deep in the torso. These numerical results also illustrate the complicated wave behavior that emerges when a body is present. The TEM resonator simulation allowed comparison of traveling wave excitation with standard quadrature excitation, showing that while the traveling wave B +1 per unit drive voltage is much less than that of the TEM system, the square of the average B +1 compared to peak specific absorption rate (SAR) values can be comparable in certain imaging planes. Both systems produce highly inhomogeneous excitation of MR signal in the torso, suggesting that B(1) shimming or other parallel transmission methods are necessary for 7 T whole body imaging. Copyright © 2011 Wiley-Liss, Inc.

[Survival Strategies of Aspergillus in the Human Body].

PubMed

Tashiro, Masato; Izumikawa, Koichi

2017-01-01

 The human body is a hostile environment for Aspergillus species, which originally live outside the human body. There are lots of elimination mechanisms against Aspergillus inhaled into the human body, such as high body temperature, soluble lung components, mucociliary clearance mechanism, or responses of phagocytes. Aspergillus fumigatus, which is the primary causative agent of human infections among the human pathogenic species of Aspergillus, defend itself from the hostile human body environment by various mechanisms, such as thermotolerance, mycotoxin production, and characteristic morphological features. Here we review mechanisms of defense in Aspergillus against elimination from the human body.

Estimation of Human Body Volume (BV) from Anthropometric Measurements Based on Three-Dimensional (3D) Scan Technique.

PubMed

Liu, Xingguo; Niu, Jianwei; Ran, Linghua; Liu, Taijie

2017-08-01

This study aimed to develop estimation formulae for the total human body volume (BV) of adult males using anthropometric measurements based on a three-dimensional (3D) scanning technique. Noninvasive and reliable methods to predict the total BV from anthropometric measurements based on a 3D scan technique were addressed in detail. A regression analysis of BV based on four key measurements was conducted for approximately 160 adult male subjects. Eight total models of human BV show that the predicted results fitted by the regression models were highly correlated with the actual BV (p < 0.001). Two metrics, the mean value of the absolute difference between the actual and predicted BV (V error ) and the mean value of the ratio between V error and actual BV (RV error ), were calculated. The linear model based on human weight was recommended as the most optimal due to its simplicity and high efficiency. The proposed estimation formulae are valuable for estimating total body volume in circumstances in which traditional underwater weighing or air displacement plethysmography is not applicable or accessible. This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.

Hunting for the beat in the body: on period and phase locking in music-induced movement.

PubMed

Burger, Birgitta; Thompson, Marc R; Luck, Geoff; Saarikallio, Suvi H; Toiviainen, Petri

2014-01-01

Music has the capacity to induce movement in humans. Such responses during music listening are usually spontaneous and range from tapping to full-body dancing. However, it is still unclear how humans embody musical structures to facilitate entrainment. This paper describes two experiments, one dealing with period locking to different metrical levels in full-body movement and its relationships to beat- and rhythm-related musical characteristics, and the other dealing with phase locking in the more constrained condition of sideways swaying motions. Expected in Experiment 1 was that music with clear and strong beat structures would facilitate more period-locked movement. Experiment 2 was assumed to yield a common phase relationship between participants' swaying movements and the musical beat. In both experiments optical motion capture was used to record participants' movements. In Experiment 1 a window-based period-locking probability index related to four metrical levels was established, based on acceleration data in three dimensions. Subsequent correlations between this index and musical characteristics of the stimuli revealed pulse clarity to be related to periodic movement at the tactus level, and low frequency flux to mediolateral and anteroposterior movement at both tactus and bar levels. At faster tempi higher metrical levels became more apparent in participants' movement. Experiment 2 showed that about half of the participants showed a stable phase relationship between movement and beat, with superior-inferior movement most often being synchronized to the tactus level, whereas mediolateral movement was rather synchronized to the bar level. However, the relationship between movement phase and beat locations was not consistent between participants, as the beat locations occurred at different phase angles of their movements. The results imply that entrainment to music is a complex phenomenon, involving the whole body and occurring at different metrical levels.

UPLC/MS MS data of testosterone metabolites in human and zebrafish liver microsomes and whole zebrafish larval microsomes.

PubMed

Saad, Moayad; Bijttebier, Sebastiaan; Matheeussen, An; Verbueken, Evy; Pype, Casper; Casteleyn, Christophe; Van Ginneken, Chris; Maes, Louis; Cos, Paul; Van Cruchten, Steven

2018-02-01

This article represents data regarding a study published in Toxicology in vitro entitled " in vitro CYP-mediated drug metabolism in the zebrafish (embryo) using human reference compounds" (Saad et al., 2017) [1]. Data were acquired with ultra-performance liquid chromatography - accurate mass mass spectrometry (UPLC-amMS). A full spectrum scan was conducted for the testosterone (TST) metabolites from the microsomal stability assay in zebrafish and humans. The microsomal proteins were extracted from adult zebrafish male (MLM) and female (FLM) livers, whole body homogenates of 96 h post fertilization larvae (EM) and a pool of human liver microsomes from 50 donors (HLM). Data are expressed as the abundance from the extracted ion chromatogram of the metabolites.

In-vehicle group activity modeling and simulation in sensor-based virtual environment

NASA Astrophysics Data System (ADS)

Shirkhodaie, Amir; Telagamsetti, Durga; Poshtyar, Azin; Chan, Alex; Hu, Shuowen

2016-05-01

Human group activity recognition is a very complex and challenging task, especially for Partially Observable Group Activities (POGA) that occur in confined spaces with limited visual observability and often under severe occultation. In this paper, we present IRIS Virtual Environment Simulation Model (VESM) for the modeling and simulation of dynamic POGA. More specifically, we address sensor-based modeling and simulation of a specific category of POGA, called In-Vehicle Group Activities (IVGA). In VESM, human-alike animated characters, called humanoids, are employed to simulate complex in-vehicle group activities within the confined space of a modeled vehicle. Each articulated humanoid is kinematically modeled with comparable physical attributes and appearances that are linkable to its human counterpart. Each humanoid exhibits harmonious full-body motion - simulating human-like gestures and postures, facial impressions, and hands motions for coordinated dexterity. VESM facilitates the creation of interactive scenarios consisting of multiple humanoids with different personalities and intentions, which are capable of performing complicated human activities within the confined space inside a typical vehicle. In this paper, we demonstrate the efficiency and effectiveness of VESM in terms of its capabilities to seamlessly generate time-synchronized, multi-source, and correlated imagery datasets of IVGA, which are useful for the training and testing of multi-source full-motion video processing and annotation. Furthermore, we demonstrate full-motion video processing of such simulated scenarios under different operational contextual constraints.

Computational dosimetry for grounded and ungrounded human models due to contact current

NASA Astrophysics Data System (ADS)

Chan, Kwok Hung; Hattori, Junya; Laakso, Ilkka; Hirata, Akimasa; Taki, Masao

2013-08-01

This study presents the computational dosimetry of contact currents for grounded and ungrounded human models. The uncertainty of the quasi-static (QS) approximation of the in situ electric field induced in a grounded/ungrounded human body due to the contact current is first estimated. Different scenarios of cylindrical and anatomical human body models are considered, and the results are compared with the full-wave analysis. In the QS analysis, the induced field in the grounded cylindrical model is calculated by the QS finite-difference time-domain (QS-FDTD) method, and compared with the analytical solution. Because no analytical solution is available for the grounded/ungrounded anatomical human body model, the results of the QS-FDTD method are then compared with those of the conventional FDTD method. The upper frequency limit for the QS approximation in the contact current dosimetry is found to be 3 MHz, with a relative local error of less than 10%. The error increases above this frequency, which can be attributed to the neglect of the displacement current. The QS or conventional FDTD method is used for the dosimetry of induced electric field and/or specific absorption rate (SAR) for a contact current injected into the index finger of a human body model in the frequency range from 10 Hz to 100 MHz. The in situ electric fields or SAR are compared with the basic restrictions in the international guidelines/standards. The maximum electric field or the 99th percentile value of the electric fields appear not only in the fat and muscle tissues of the finger, but also around the wrist, forearm, and the upper arm. Some discrepancies are observed between the basic restrictions for the electric field and SAR and the reference levels for the contact current, especially in the extremities. These discrepancies are shown by an equation that relates the current density, tissue conductivity, and induced electric field in the finger with a cross-sectional area of 1 cm2.

Recent Progress of Textile-Based Wearable Electronics: A Comprehensive Review of Materials, Devices, and Applications.

PubMed

Heo, Jae Sang; Eom, Jimi; Kim, Yong-Hoon; Park, Sung Kyu

2018-01-01

Wearable electronics are emerging as a platform for next-generation, human-friendly, electronic devices. A new class of devices with various functionality and amenability for the human body is essential. These new conceptual devices are likely to be a set of various functional devices such as displays, sensors, batteries, etc., which have quite different working conditions, on or in the human body. In these aspects, electronic textiles seem to be a highly suitable possibility, due to the unique characteristics of textiles such as being light weight and flexible and their inherent warmth and the property to conform. Therefore, e-textiles have evolved into fiber-based electronic apparel or body attachable types in order to foster significant industrialization of the key components with adaptable formats. Although the advances are noteworthy, their electrical performance and device features are still unsatisfactory for consumer level e-textile systems. To solve these issues, innovative structural and material designs, and novel processing technologies have been introduced into e-textile systems. Recently reported and significantly developed functional materials and devices are summarized, including their enhanced optoelectrical and mechanical properties. Furthermore, the remaining challenges are discussed, and effective strategies to facilitate the full realization of e-textile systems are suggested. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

CRUX: a Compliant Robotic Upper-Extremity eXosuit for Lightweight, Portable, Multi-DoF Muscular Augmentation

NASA Technical Reports Server (NTRS)

Lessard, Steven; Pansodtee, Pattawong; Robbins, Ash; Baltaxe-Admony, Leya Breanna; Teodorescu, Mircea; Kurniawan,Sri; Agogino, Adrian; Kurniawan, Sri

2017-01-01

Wearable robots can potentially offer their users enhanced stability and strength. These augmentations are ideally designed to actuate harmoniously with the users movements and provide extra force as needed. The creation of such robots, however, is particularly challenging due to the complexity of the underlying human body. In this paper, we present a compliant, robotic exosuit for upper-extremities called CRUX. This exosuit, inspired by tensegrity models of the human arm, features a lightweight (1.3 kg), flexible design for portability. We also show how CRUX maintains full flexibility of the upper-extremities for its users while providing multi- DoF augmentative strength to the major muscles of the arm, as evident by tracking the heart rate of an individual exercising said arm. Exosuits such as CRUX may be useful in physical therapy and in extreme environments where users are expected to exert their bodies to the fullest extent.

Space trajectory calculation based on G-sensor

NASA Astrophysics Data System (ADS)

Xu, Biya; Zhan, Yinwei; Shao, Yang

2017-08-01

At present, without full use of the mobile phone around us, most of the research in human body posture recognition field is use camera or portable acceleration sensor to collect data. In this paper, G-sensor built-in mobile phone is use to collect data. After processing data with the way of moving average filter and acceleration integral, joint point's space three-dimensional coordinates can be abtained accurately.

An Objective Evaluation of Mass Scaling Techniques Utilizing Computational Human Body Finite Element Models.

PubMed

Davis, Matthew L; Scott Gayzik, F

2016-10-01

Biofidelity response corridors developed from post-mortem human subjects are commonly used in the design and validation of anthropomorphic test devices and computational human body models (HBMs). Typically, corridors are derived from a diverse pool of biomechanical data and later normalized to a target body habitus. The objective of this study was to use morphed computational HBMs to compare the ability of various scaling techniques to scale response data from a reference to a target anthropometry. HBMs are ideally suited for this type of study since they uphold the assumptions of equal density and modulus that are implicit in scaling method development. In total, six scaling procedures were evaluated, four from the literature (equal-stress equal-velocity, ESEV, and three variations of impulse momentum) and two which are introduced in the paper (ESEV using a ratio of effective masses, ESEV-EffMass, and a kinetic energy approach). In total, 24 simulations were performed, representing both pendulum and full body impacts for three representative HBMs. These simulations were quantitatively compared using the International Organization for Standardization (ISO) ISO-TS18571 standard. Based on these results, ESEV-EffMass achieved the highest overall similarity score (indicating that it is most proficient at scaling a reference response to a target). Additionally, ESEV was found to perform poorly for two degree-of-freedom (DOF) systems. However, the results also indicated that no single technique was clearly the most appropriate for all scenarios.

Human body region enhancement method based on Kinect infrared imaging

NASA Astrophysics Data System (ADS)

Yang, Lei; Fan, Yubo; Song, Xiaowei; Cai, Wenjing

2016-10-01

To effectively improve the low contrast of human body region in the infrared images, a combing method of several enhancement methods is utilized to enhance the human body region. Firstly, for the infrared images acquired by Kinect, in order to improve the overall contrast of the infrared images, an Optimal Contrast-Tone Mapping (OCTM) method with multi-iterations is applied to balance the contrast of low-luminosity infrared images. Secondly, to enhance the human body region better, a Level Set algorithm is employed to improve the contour edges of human body region. Finally, to further improve the human body region in infrared images, Laplacian Pyramid decomposition is adopted to enhance the contour-improved human body region. Meanwhile, the background area without human body region is processed by bilateral filtering to improve the overall effect. With theoretical analysis and experimental verification, the results show that the proposed method could effectively enhance the human body region of such infrared images.

Automatic identification of inertial sensor placement on human body segments during walking

PubMed Central

2013-01-01

Background Current inertial motion capture systems are rarely used in biomedical applications. The attachment and connection of the sensors with cables is often a complex and time consuming task. Moreover, it is prone to errors, because each sensor has to be attached to a predefined body segment. By using wireless inertial sensors and automatic identification of their positions on the human body, the complexity of the set-up can be reduced and incorrect attachments are avoided. We present a novel method for the automatic identification of inertial sensors on human body segments during walking. This method allows the user to place (wireless) inertial sensors on arbitrary body segments. Next, the user walks for just a few seconds and the segment to which each sensor is attached is identified automatically. Methods Walking data was recorded from ten healthy subjects using an Xsens MVN Biomech system with full-body configuration (17 inertial sensors). Subjects were asked to walk for about 6 seconds at normal walking speed (about 5 km/h). After rotating the sensor data to a global coordinate frame with x-axis in walking direction, y-axis pointing left and z-axis vertical, RMS, mean, and correlation coefficient features were extracted from x-, y- and z-components and magnitudes of the accelerations, angular velocities and angular accelerations. As a classifier, a decision tree based on the C4.5 algorithm was developed using Weka (Waikato Environment for Knowledge Analysis). Results and conclusions After testing the algorithm with 10-fold cross-validation using 31 walking trials (involving 527 sensors), 514 sensors were correctly classified (97.5%). When a decision tree for a lower body plus trunk configuration (8 inertial sensors) was trained and tested using 10-fold cross-validation, 100% of the sensors were correctly identified. This decision tree was also tested on walking trials of 7 patients (17 walking trials) after anterior cruciate ligament reconstruction, which also resulted in 100% correct identification, thus illustrating the robustness of the method. PMID:23517757

Automatic identification of inertial sensor placement on human body segments during walking.

PubMed

Weenk, Dirk; van Beijnum, Bert-Jan F; Baten, Chris T M; Hermens, Hermie J; Veltink, Peter H

2013-03-21

Current inertial motion capture systems are rarely used in biomedical applications. The attachment and connection of the sensors with cables is often a complex and time consuming task. Moreover, it is prone to errors, because each sensor has to be attached to a predefined body segment. By using wireless inertial sensors and automatic identification of their positions on the human body, the complexity of the set-up can be reduced and incorrect attachments are avoided.We present a novel method for the automatic identification of inertial sensors on human body segments during walking. This method allows the user to place (wireless) inertial sensors on arbitrary body segments. Next, the user walks for just a few seconds and the segment to which each sensor is attached is identified automatically. Walking data was recorded from ten healthy subjects using an Xsens MVN Biomech system with full-body configuration (17 inertial sensors). Subjects were asked to walk for about 6 seconds at normal walking speed (about 5 km/h). After rotating the sensor data to a global coordinate frame with x-axis in walking direction, y-axis pointing left and z-axis vertical, RMS, mean, and correlation coefficient features were extracted from x-, y- and z-components and magnitudes of the accelerations, angular velocities and angular accelerations. As a classifier, a decision tree based on the C4.5 algorithm was developed using Weka (Waikato Environment for Knowledge Analysis). After testing the algorithm with 10-fold cross-validation using 31 walking trials (involving 527 sensors), 514 sensors were correctly classified (97.5%). When a decision tree for a lower body plus trunk configuration (8 inertial sensors) was trained and tested using 10-fold cross-validation, 100% of the sensors were correctly identified. This decision tree was also tested on walking trials of 7 patients (17 walking trials) after anterior cruciate ligament reconstruction, which also resulted in 100% correct identification, thus illustrating the robustness of the method.

People watching: The perception of the relative body proportions of the self and others.

PubMed

Linkenauger, Sally A; Kirby, Laura R; McCulloch, Kathleen C; Longo, Matthew R

2017-07-01

We have an abundance of perceptual information from multiple modalities specifying our body proportions. Consequently, it seems reasonable for researchers to assume that we have an accurate perception of our body proportions. In contrast to this intuition, recent research has shown large, striking distortions in people's perceptions of the relative proportions of their own bodies. Specifically, individuals show large distortions when estimating the length of their body parts with a corporal metric, such as the hand, but not with a non-corporal object of the same length (Linkenauger et al., 2015). However, it remains unclear whether these distortions are specific to the perception of the relative proportions of one's own body or whether they generalize to the perception of the relative proportions of all human bodies. To assess this, individuals judged the relative lengths of either their own body parts or the body parts of another individual. We found that people have distorted perceptions of relative body proportions even when viewing the bodies of others. These distortions were greater when estimating the relative body parts of someone of the same gender. These results suggest our implicit full body representation is distorted and influences our perceptions of other people's bodies, especially if the other person's body is similar to our own. Copyright © 2017 Elsevier Ltd. All rights reserved.

The use of biomechanics in the study of movement in microgravity

NASA Technical Reports Server (NTRS)

Gregor, R. J.; Broker, J. P.; Ryan, M. M.

1994-01-01

As biomechanists interested in the adaptability of the human body to microgravity conditions, it appears that our job is not only to make sure that the astronauts can function adequately in space but also that they can function upon their return to Earth. This is especially significant since many of the projects now being designed at NASA concern themselves with humans performing for up to 3 years in microgravity. While the Extended Duration Orbiter flights may last 30 to 60 days, future flights to Mars using current propulsion technology may last from 2 to 3 years. It is for this range of time that the adaptation process must be studied. Specifically, biomechanists interested in space travel realize that human performance capabilities will change as a result of exposure to microgravity. The role of the biomechanist then is to first understand the nature of the changes realized by the body. These changes include adaptation by the musculoskeletal system, the nervous system, cardiorespiratory system, and the cardiovascular system. As biomechanists, it is also our role to take part in the development of countermeasure programs that involve some form of regular exercise. Exercise countermeasure programs should include a variety of modalities with full knowledge of the loads imposed on the body by these modalities. Any exercise programs that are to be conducted by the astronauts during space travel must consider the fact that the musculoskeletal and neuromuscular systems degrade as a function of flight duration. Additionally, it must be understood that the central nervous system modifies its output in the control of the human body during space flight and most importantly, we must prepare the astronauts for their return to one g.

Using Transom Jack in the Human Engineering Analysis of the Materials Science Research Rack-1 and Quench Module Insert

NASA Technical Reports Server (NTRS)

Dunn, Mariea C.; Alves, Jeffrey R.; Hutchinson, Sonya L.

1999-01-01

This paper describes the human engineering analysis performed on the Materials Science Research Rack-1 and Quench Module Insert (MSRR-1/QMI) using Transom Jack (Jack) software. The Jack software was used to model a virtual environment consisting of the MSRR-1/QMI hardware configuration and human figures representing the 95th percentile male and 5th percentile female. The purpose of the simulation was to assess the human interfaces in the design for their ability to meet the requirements of the Pressurized Payloads Interface Requirements Document - International Space Program, Revision C (SSP 57000). Jack was used in the evaluation because of its ability to correctly model anthropometric body measurements and the physical behavior of astronauts working in microgravity, which is referred to as the neutral body posture. The Jack model allows evaluation of crewmember interaction with hardware through task simulation including but not limited to collision avoidance behaviors, hand/eye coordination, reach path planning, and automatic grasping to part contours. Specifically, this virtual simulation depicts the human figures performing the QMI installation and check-out, sample cartridge insertion and removal, and gas bottle drawer removal. These tasks were evaluated in terms of adequate clearance in reach envelopes, adequate accessibility in work envelopes, appropriate line of sight in visual envelopes, and accommodation of full size range for male and female stature maneuverability. The results of the human engineering analysis virtual simulation indicate that most of the associated requirements of SSP 57000 were met. However, some hardware design considerations and crew procedures modifications are recommended to improve accessibility, provide an adequate work envelope, reduce awkward body posture, and eliminate permanent protrusions.

Determination of Percent Body Fat Using 3D Whole Body Laser Scanning: A Preliminary Investigation

DTIC Science & Technology

2006-11-01

S.B., Lohman, T.G., Wang, Z., and Going, S.B., 2005: Human body composition: Human Kinetics : Champaign, IL. Heyward, V.H. and Wagner, D.R...2004: Applied body composition assessment: Human Kinetics : Champaign, IL. Hodgdon, J.A., and Beckett, M.B., 1984a: Prediction of percent body fat...ethnicity. In: Human body Composition., Heymsfield, S.B., Lohman, T.G., Wang, Z., and Going, S.B (eds.). Human Kinetics : Champaign, IL. Marriott

Body metaphors--reading the body in contemporary culture.

PubMed

Skara, Danica

2004-01-01

This paper addresses the linguistic reframing of the human body in contemporary culture. Our aim is to provide a linguistic description of the ways in which the body is represented in modern English language. First, we will try to focus on body metaphors in general. We have collected a sample of 300 words and phrases functioning as body metaphors in modern English language. Reading the symbolism of the body we are witnessing changes in the basic metaphorical structuring of the human body. The results show that new vocabulary binds different fields of knowledge associated with machines and human beings according to a shared textual frame: human as computer and computer as human metaphor. Humans are almost blended with computers and vice versa. This metaphorical use of the human body and its parts reveals not only currents of unconscious though but also the structures of modern society and culture.

Human body segmentation via data-driven graph cut.

PubMed

Li, Shifeng; Lu, Huchuan; Shao, Xingqing

2014-11-01

Human body segmentation is a challenging and important problem in computer vision. Existing methods usually entail a time-consuming training phase for prior knowledge learning with complex shape matching for body segmentation. In this paper, we propose a data-driven method that integrates top-down body pose information and bottom-up low-level visual cues for segmenting humans in static images within the graph cut framework. The key idea of our approach is first to exploit human kinematics to search for body part candidates via dynamic programming for high-level evidence. Then, by using the body parts classifiers, obtaining bottom-up cues of human body distribution for low-level evidence. All the evidence collected from top-down and bottom-up procedures are integrated in a graph cut framework for human body segmentation. Qualitative and quantitative experiment results demonstrate the merits of the proposed method in segmenting human bodies with arbitrary poses from cluttered backgrounds.

Infants' Responses to Real Humans and Representations of Humans

ERIC Educational Resources Information Center

Heron, Michelle; Slaughter, Virginia

2010-01-01

Infants' responses to typical and scrambled human body shapes were assessed in relation to the realism of the human body stimuli presented. In four separate experiments, infants were familiarized to typical human bodies and then shown a series of scrambled human bodies on the test. Looking behaviour was assessed in response to a range of different…

The foreign body response: at the interface of surgery and bioengineering.

PubMed

Major, Melanie R; Wong, Victor W; Nelson, Emily R; Longaker, Michael T; Gurtner, Geoffrey C

2015-05-01

The surgical implantation of materials and devices has dramatically increased over the past decade. This trend is expected to continue with the broadening application of biomaterials and rapid expansion of aging populations. One major factor that limits the potential of implantable materials and devices is the foreign body response, an immunologic reaction characterized by chronic inflammation, foreign body giant cell formation, and fibrotic capsule formation. The English literature on the foreign body response to implanted materials and devices is reviewed. Fibrotic encapsulation can cause device malfunction and dramatically limit the function of an implanted medical device or material. Basic science studies suggest a role for immune and inflammatory pathways at the implant-host interface that drive the foreign body response. Current strategies that aim to modulate the host response and improve construct biocompatibility appear promising. This review article summarizes recent basic science, preclinical, and clinicopathologic studies examining the mechanisms driving the foreign body response, with particular focus on breast implants and synthetic meshes. Understanding these molecular and cellular mechanisms will be critical for achieving the full potential of implanted biomaterials to restore human tissues and organs.

Equivalent magnetic vector potential model for low-frequency magnetic exposure assessment

NASA Astrophysics Data System (ADS)

Diao, Y. L.; Sun, W. N.; He, Y. Q.; Leung, S. W.; Siu, Y. M.

2017-10-01

In this paper, a novel source model based on a magnetic vector potential for the assessment of induced electric field strength in a human body exposed to the low-frequency (LF) magnetic field of an electrical appliance is presented. The construction of the vector potential model requires only a single-component magnetic field to be measured close to the appliance under test, hence relieving considerable practical measurement effort—the radial basis functions (RBFs) are adopted for the interpolation of discrete measurements; the magnetic vector potential model can then be directly constructed by summing a set of simple algebraic functions of RBF parameters. The vector potentials are then incorporated into numerical calculations as the equivalent source for evaluations of the induced electric field in the human body model. The accuracy and effectiveness of the proposed model are demonstrated by comparing the induced electric field in a human model to that of the full-wave simulation. This study presents a simple and effective approach for modelling the LF magnetic source. The result of this study could simplify the compliance test procedure for assessing an electrical appliance regarding LF magnetic exposure.

Equivalent magnetic vector potential model for low-frequency magnetic exposure assessment.

PubMed

Diao, Y L; Sun, W N; He, Y Q; Leung, S W; Siu, Y M

2017-09-21

In this paper, a novel source model based on a magnetic vector potential for the assessment of induced electric field strength in a human body exposed to the low-frequency (LF) magnetic field of an electrical appliance is presented. The construction of the vector potential model requires only a single-component magnetic field to be measured close to the appliance under test, hence relieving considerable practical measurement effort-the radial basis functions (RBFs) are adopted for the interpolation of discrete measurements; the magnetic vector potential model can then be directly constructed by summing a set of simple algebraic functions of RBF parameters. The vector potentials are then incorporated into numerical calculations as the equivalent source for evaluations of the induced electric field in the human body model. The accuracy and effectiveness of the proposed model are demonstrated by comparing the induced electric field in a human model to that of the full-wave simulation. This study presents a simple and effective approach for modelling the LF magnetic source. The result of this study could simplify the compliance test procedure for assessing an electrical appliance regarding LF magnetic exposure.

Human-Inspired Eigenmovement Concept Provides Coupling-Free Sensorimotor Control in Humanoid Robot.

PubMed

Alexandrov, Alexei V; Lippi, Vittorio; Mergner, Thomas; Frolov, Alexander A; Hettich, Georg; Husek, Dusan

2017-01-01

Control of a multi-body system in both robots and humans may face the problem of destabilizing dynamic coupling effects arising between linked body segments. The state of the art solutions in robotics are full state feedback controllers. For human hip-ankle coordination, a more parsimonious and theoretically stable alternative to the robotics solution has been suggested in terms of the Eigenmovement (EM) control. Eigenmovements are kinematic synergies designed to describe the multi DoF system, and its control, with a set of independent, and hence coupling-free , scalar equations. This paper investigates whether the EM alternative shows "real-world robustness" against noisy and inaccurate sensors, mechanical non-linearities such as dead zones, and human-like feedback time delays when controlling hip-ankle movements of a balancing humanoid robot. The EM concept and the EM controller are introduced, the robot's dynamics are identified using a biomechanical approach, and robot tests are performed in a human posture control laboratory. The tests show that the EM controller provides stable control of the robot with proactive ("voluntary") movements and reactive balancing of stance during support surface tilts and translations. Although a preliminary robot-human comparison reveals similarities and differences, we conclude (i) the Eigenmovement concept is a valid candidate when different concepts of human sensorimotor control are considered, and (ii) that human-inspired robot experiments may help to decide in future the choice among the candidates and to improve the design of humanoid robots and robotic rehabilitation devices.

Human-Inspired Eigenmovement Concept Provides Coupling-Free Sensorimotor Control in Humanoid Robot

PubMed Central

Alexandrov, Alexei V.; Lippi, Vittorio; Mergner, Thomas; Frolov, Alexander A.; Hettich, Georg; Husek, Dusan

2017-01-01

Control of a multi-body system in both robots and humans may face the problem of destabilizing dynamic coupling effects arising between linked body segments. The state of the art solutions in robotics are full state feedback controllers. For human hip-ankle coordination, a more parsimonious and theoretically stable alternative to the robotics solution has been suggested in terms of the Eigenmovement (EM) control. Eigenmovements are kinematic synergies designed to describe the multi DoF system, and its control, with a set of independent, and hence coupling-free, scalar equations. This paper investigates whether the EM alternative shows “real-world robustness” against noisy and inaccurate sensors, mechanical non-linearities such as dead zones, and human-like feedback time delays when controlling hip-ankle movements of a balancing humanoid robot. The EM concept and the EM controller are introduced, the robot's dynamics are identified using a biomechanical approach, and robot tests are performed in a human posture control laboratory. The tests show that the EM controller provides stable control of the robot with proactive (“voluntary”) movements and reactive balancing of stance during support surface tilts and translations. Although a preliminary robot-human comparison reveals similarities and differences, we conclude (i) the Eigenmovement concept is a valid candidate when different concepts of human sensorimotor control are considered, and (ii) that human-inspired robot experiments may help to decide in future the choice among the candidates and to improve the design of humanoid robots and robotic rehabilitation devices. PMID:28487646

Bayesian integration and non-linear feedback control in a full-body motor task.

PubMed

Stevenson, Ian H; Fernandes, Hugo L; Vilares, Iris; Wei, Kunlin; Körding, Konrad P

2009-12-01

A large number of experiments have asked to what degree human reaching movements can be understood as being close to optimal in a statistical sense. However, little is known about whether these principles are relevant for other classes of movements. Here we analyzed movement in a task that is similar to surfing or snowboarding. Human subjects stand on a force plate that measures their center of pressure. This center of pressure affects the acceleration of a cursor that is displayed in a noisy fashion (as a cloud of dots) on a projection screen while the subject is incentivized to keep the cursor close to a fixed position. We find that salient aspects of observed behavior are well-described by optimal control models where a Bayesian estimation model (Kalman filter) is combined with an optimal controller (either a Linear-Quadratic-Regulator or Bang-bang controller). We find evidence that subjects integrate information over time taking into account uncertainty. However, behavior in this continuous steering task appears to be a highly non-linear function of the visual feedback. While the nervous system appears to implement Bayes-like mechanisms for a full-body, dynamic task, it may additionally take into account the specific costs and constraints of the task.

Combined Induction of Rubber-Hand Illusion and Out-of-Body Experiences

PubMed Central

Olivé, Isadora; Berthoz, Alain

2012-01-01

The emergence of self-consciousness depends on several processes: those of body ownership, attributing self-identity to the body, and those of self-location, localizing our sense of self. Studies of phenomena like the rubber-hand illusion (RHi) and out-of-body experience (OBE) investigate these processes, respectively for representations of a body-part and the full-body. It is supposed that RHi only target processes related to body-part representations, while OBE only relates to full-body representations. The fundamental question whether the body-part and the full-body illusions relate to each other is nevertheless insufficiently investigated. In search for a link between body-part and full-body illusions in the brain we developed a behavioral task combining adapted versions of the RHi and OBE. Furthermore, for the investigation of this putative link we investigated the role of sensory and motor cues. We established a spatial dissociation between visual and proprioceptive feedback of a hand perceived through virtual reality in rest or action. Two experimental measures were introduced: one for the body-part illusion, the proprioceptive drift of the perceived localization of the hand, and one for the full-body illusion, the shift in subjective-straight-ahead (SSA). In the rest and action conditions it was observed that the proprioceptive drift of the left hand and the shift in SSA toward the manipulation side are equivalent. The combined effect was dependent on the manipulation of the visual representation of body parts, rejecting any main or even modulatory role for relevant motor programs. Our study demonstrates for the first time that there is a systematic relationship between the body-part illusion and the full-body illusion, as shown by our measures. This suggests a link between the representations in the brain of a body-part and the full-body, and consequently a common mechanism underpinning both forms of ownership and self-location. PMID:22675312

Links between Evolution, Development, Human Anatomy, Pathology, and Medicine, with A Proposition of A Re-defined Anatomical Position and Notes on Constraints and Morphological "Imperfections".

PubMed

Diogo, Rui; Molnar, Julia

2016-06-01

Surprisingly the oldest formal discipline in medicine (anatomy) has not yet felt the full impact of evolutionary developmental biology. In medical anatomy courses and textbooks, the human body is still too often described as though it is a "perfect machine." In fact, the study of human anatomy predates evolutionary theory; therefore, many of its conventions continue to be outdated, making it difficult to study, understand, and treat the human body, and to compare it with that of other, nonbipedal animals, including other primates. Moreover, such an erroneous view of our anatomy as "perfect" can be used to fuel nonevolutionary ideologies such as intelligent design. In the section An Evolutionary and Developmental Approach to Human Anatomical Position of this paper, we propose the redefinition of the "human standard anatomical position" used in textbooks to be consistent with human evolutionary and developmental history. This redefined position also simplifies, for students and practitioners of the health professions, the study and learning of embryonic muscle groups (each group including muscles derived from the same/ontogenetically closely related primordium/primordia) and joint movements and highlights the topological correspondence between the upper and lower limbs. Section Evolutionary and Developmental Constraints, "Imperfections" and Sports Pathologies continues the theme by describing examples of apparently "illogical" characteristics of the human body that only make sense when one understands the developmental and evolutionary constraints that have accumulated over millions of years. We focus, in particular, on musculoskeletal functional problems and sports pathologies to emphasize the links with pathology and medicine. These examples demonstrate how incorporating evolutionary theory into anatomy education can be helpful for medical students, teachers, researchers, and physicians, as well as for anatomists, functional morphologists, and evolutionary and developmental biologists. © 2016 Wiley Periodicals, Inc.

Preliminary experiments on dynamic biology of micro-organisms to avoid any specific full-blown syndrome on humans

NASA Astrophysics Data System (ADS)

Meer, Sneer

2002-06-01

The aim of this paper is to apply an efficient system to detect, identify and quicken suppression of any dangerous micro-organism which threatens the health of the human body in any form. It is well known that some specimens of this kind of possess a specific energy related to their speed of division, toxin emissions and high-powered interaction with human and animal cells which have the capacity to provide certain deadly full-blown syndromes. Many problems relating to the above-mentioned properties have not been clarified to date, and it is vital to find a rapid and valid reply as soon as possible. Inter-disciplinary sciences directed us to start some experiments to solve such problems, considering that the human body is dotted with a multiple interactive system of energy release, a fact which can explain the source of the micro-organism's energy also, for their necessity to manifest their deadly pathology. From practical preliminary experiments with some micro-mechanical systems using light-microscopy, connected to video TV Recorder System, one obtains optical enlarged TV images of certain processes which indicated the right way towards our crucial target; ie: the preparation of safe vaccines and safe medicines. This will constitute a basic system to a void deadly manifestations of dangerous micro-organisms and/or even regular infections on earth and in space, a system which will probably be applied at the ISS Space Station and other future actions in space in long and very long flights. We look forward to applying this system of dynamic biology towards preparation of a real and valid vaccine(s) against HIV virus on AIDS diseases.

Implementation of whole body scanner for determining somatotype index at Chang Gung Memorial Hospital.

PubMed

Liu, T H; Chiou, W K; Lin, J D; Yu, C Y

2001-11-01

Body mass index (BMI) and waist-hip ratio (WHR) using 1-dimensional circumference data have been proven to be highly related to blood pressure and total cholesterol; these 2 indices have been widely used as health indicators in preventive diagnosis and health examination. Sophisticated software, which allows calculation of the triangular mesh related to the body surface in 3D space, is capable of computing the circumference, width, sectional surface, volume, and surface area of the body. Chang Gung Whole Body Scanner (CGWBS) was used to capture 3D whole body surface images. In this study, the human body was divided into 10 segments consisting of the head, breast, wrist, hip, upper arm, forearm, hand, thigh, calf, and foot. Five independent assessments were made on a total of 32 anthropometric sites, including 12 circumferences, 3 widths, 3 profile areas, 7 surface areas, and 7 volumes. In this study, the somatotype index (SI) was computed through anthropometric data after 1,323 subjects were investigated. Correlation analysis was used to describe the relationship between BMI, WHR, SI, and anthropometric data. One-way analysis of variance (ANOVA) and Duncan's multiple range tests were used to examine differences between examination variables across sex and SI groups. This study found 4 somatotypes from anthropometric data. SI determined by CGWBS has better correlation with anthropometry than WHR or BMI. Of the 644 male subjects, 155 were in the ectomorph group, 232 in the semi-mesomorph group, 136 in the full-mesomorph group, and 121 in the endomorph group. Of the 679 female subjects, 160 were in the ectomorph group, 235 in the semi-mesomorph group, 168 in the full-mesomorph group, and 116 in the endomorph group. The results show that SI has great potential to perform precise somatotype classification.

The Human Retrosplenial Cortex and Thalamus Code Head Direction in a Global Reference Frame.

PubMed

Shine, Jonathan P; Valdés-Herrera, José P; Hegarty, Mary; Wolbers, Thomas

2016-06-15

Spatial navigation is a multisensory process involving integration of visual and body-based cues. In rodents, head direction (HD) cells, which are most abundant in the thalamus, integrate these cues to code facing direction. Human fMRI studies examining HD coding in virtual environments (VE) have reported effects in retrosplenial complex and (pre-)subiculum, but not the thalamus. Furthermore, HD coding appeared insensitive to global landmarks. These tasks, however, provided only visual cues for orientation, and attending to global landmarks did not benefit task performance. In the present study, participants explored a VE comprising four separate locales, surrounded by four global landmarks. To provide body-based cues, participants wore a head-mounted display so that physical rotations changed facing direction in the VE. During subsequent MRI scanning, subjects saw stationary views of the environment and judged whether their orientation was the same as in the preceding trial. Parameter estimates extracted from retrosplenial cortex and the thalamus revealed significantly reduced BOLD responses when HD was repeated. Moreover, consistent with rodent findings, the signal did not continue to adapt over repetitions of the same HD. These results were supported by a whole-brain analysis showing additional repetition suppression in the precuneus. Together, our findings suggest that: (1) consistent with the rodent literature, the human thalamus may integrate visual and body-based, orientation cues; (2) global reference frame cues can be used to integrate HD across separate individual locales; and (3) immersive training procedures providing full body-based cues may help to elucidate the neural mechanisms supporting spatial navigation. In rodents, head direction (HD) cells signal facing direction in the environment via increased firing when the animal assumes a certain orientation. Distinct brain regions, the retrosplenial cortex (RSC) and thalamus, code for visual and vestibular cues of orientation, respectively. Putative HD signals have been observed in human RSC but not the thalamus, potentially because body-based cues were not provided. Here, participants encoded HD in a novel virtual environment while wearing a head-mounted display to provide body-based cues for orientation. In subsequent fMRI scanning, we found evidence of an HD signal in RSC, thalamus, and precuneus. These findings harmonize rodent and human data, and suggest that immersive training procedures provide a viable way to examine the neural basis of navigation. Copyright © 2016 the authors 0270-6474/16/366371-11$15.00/0.

[An interactive three-dimensional model of the human body].

PubMed

Liem, S L

2009-01-01

Driven by advanced computer technology, it is now possible to show the human anatomy on a computer. On the internet, the Visible Body programme makes it possible to navigate in all directions through the anatomical structures of the human body, using mouse and keyboard. Visible Body is a wonderful tool to give insight in the human structures, body functions and organs.

Mapping multisensory parietal face and body areas in humans.

PubMed

Huang, Ruey-Song; Chen, Ching-fu; Tran, Alyssa T; Holstein, Katie L; Sereno, Martin I

2012-10-30

Detection and avoidance of impending obstacles is crucial to preventing head and body injuries in daily life. To safely avoid obstacles, locations of objects approaching the body surface are usually detected via the visual system and then used by the motor system to guide defensive movements. Mediating between visual input and motor output, the posterior parietal cortex plays an important role in integrating multisensory information in peripersonal space. We used functional MRI to map parietal areas that see and feel multisensory stimuli near or on the face and body. Tactile experiments using full-body air-puff stimulation suits revealed somatotopic areas of the face and multiple body parts forming a higher-level homunculus in the superior posterior parietal cortex. Visual experiments using wide-field looming stimuli revealed retinotopic maps that overlap with the parietal face and body areas in the postcentral sulcus at the most anterior border of the dorsal visual pathway. Starting at the parietal face area and moving medially and posteriorly into the lower-body areas, the median of visual polar-angle representations in these somatotopic areas gradually shifts from near the horizontal meridian into the lower visual field. These results suggest the parietal face and body areas fuse multisensory information in peripersonal space to guard an individual from head to toe.

Muscidae (Diptera) of forensic importance-an identification key to third instar larvae of the western Palaearctic region and a catalogue of the muscid carrion community.

PubMed

Grzywacz, Andrzej; Hall, Martin J R; Pape, Thomas; Szpila, Krzysztof

2017-05-01

The Muscidae is one of the main dipteran families recognized as important for medico-legal purposes. Although an association of adult flies with decomposing human and animal bodies is documented for about 200 taxa worldwide, cadavers and carrion represents a breeding habitat for considerably fewer species. Species that do colonize dead human bodies can do so under diverse environmental conditions and, under certain circumstances, Muscidae may be the only colonizers of a body. Because of difficulties in identification, many studies have identified immature and/or adult muscids only to the genus or family level. This lack of detailed species-level identifications hinders detailed investigation of their medico-legal usefulness in carrion succession-oriented experiments. Identification to species level of third instars of Muscidae of forensic importance and the utility of larval morphological characters for taxonomic purposes were subjected to an in-depth revision. A combination of characters allowing for the discrimination of third instar muscids from other forensically important dipterans is proposed. An identification key for third instar larvae, which covers the full set of cadaver-colonising species of Muscidae from the western Palaearctic (Europe, North Africa, Middle East), is provided. This key will facilitate more detailed and species-specific knowledge of the occurrence of Muscidae in forensic entomology experiments and real cases. The carrion-visiting Muscidae worldwide are catalogued, and those species breeding in animal carrion and dead human bodies are briefly discussed with regard to their forensic importance.

Evaluation of Propagation Characteristics Using the Human Body as an Antenna

PubMed Central

Li, Jingzhen; Liu, Yuhang; Hao, Yang

2017-01-01

In this paper, an inhomogeneous human body model was presented to investigate the propagation characteristics when the human body was used as an antenna to achieve signal transmission. Specifically, the channel gain of four scenarios, namely, (1) both TX electrode and RX electrode were placed in the air, (2) TX electrode was attached on the human body, and RX electrode was placed in the air, (3) TX electrode was placed in the air, and RX electrode was attached on the human body, (4) both the TX electrode and RX electrode were attached on the human body, were studied through numerical simulation in the frequency range 1 MHz to 90 MHz. Furthermore, the comparisons of input efficiency, accepted efficiency, total efficiency, absorption power of human body, and electric field distribution of different distances of four aforementioned scenarios were explored when the frequency was at 44 MHz. In addition, the influences of different human tissues, electrode position, and the distance between electrode and human body on the propagation characteristics were investigated respectively at 44 MHz. The results showed that the channel gain of Scenario 4 was the maximum when the frequency was from 1 MHz to 90 MHz. The propagation characteristics were almost independent of electrode position when the human body was using as an antenna. However, as the distance between TX electrode and human body increased, the channel gain decreased rapidly. The simulations were verified by experimental measurements. The results showed that the simulations were in agreement with the measurements. PMID:29232905

Evaluation of Propagation Characteristics Using the Human Body as an Antenna.

PubMed

Li, Jingzhen; Nie, Zedong; Liu, Yuhang; Wang, Lei; Hao, Yang

2017-12-11

In this paper, an inhomogeneous human body model was presented to investigate the propagation characteristics when the human body was used as an antenna to achieve signal transmission. Specifically, the channel gain of four scenarios, namely, (1) both TX electrode and RX electrode were placed in the air, (2) TX electrode was attached on the human body, and RX electrode was placed in the air, (3) TX electrode was placed in the air, and RX electrode was attached on the human body, (4) both the TX electrode and RX electrode were attached on the human body, were studied through numerical simulation in the frequency range 1 MHz to 90 MHz. Furthermore, the comparisons of input efficiency, accepted efficiency, total efficiency, absorption power of human body, and electric field distribution of different distances of four aforementioned scenarios were explored when the frequency was at 44 MHz. In addition, the influences of different human tissues, electrode position, and the distance between electrode and human body on the propagation characteristics were investigated respectively at 44 MHz. The results showed that the channel gain of Scenario 4 was the maximum when the frequency was from 1 MHz to 90 MHz. The propagation characteristics were almost independent of electrode position when the human body was using as an antenna. However, as the distance between TX electrode and human body increased, the channel gain decreased rapidly. The simulations were verified by experimental measurements. The results showed that the simulations were in agreement with the measurements.

Radiometric Thermometry for Wearable Deep Tissue Monitoring

NASA Astrophysics Data System (ADS)

Momenroodaki, Parisa

Microwave thermometry is an attractive non-invasive method for measuring internal body temperature. This approach has the potential of enabling a wearable device that can continuously monitor core body temperature. There are a number of health-related applications in both diagnostics and therapy, which can benefit from the knowledge of core body temperature. However,there are a limited number of device solutions, which are usually not wearable or cannot continuously monitor internal body temperature non-invasively. In this thesis, a possible path toward implementing such a thermometer is presented. The device operates in the "quiet" frequency band of 1.4 GHz which is chosen as a compromise between sensing depth and radio frequency interference (RFI). A major challenge in microwave thermometry is detecting small temperature variations of deep tissue layers from surface (skin) measurements. The type and thickness of tissue materials significantly affect the design of the probe, which has the function of receiving black-body radiation from tissues beneath it and coupling the power to a sensitive radiometric receiver. High dielectric constant contrast between skin, fat (/bone), and muscle layers suggests structures with dominant tangential component of the electric field, such as a patch or slot. Adding a layer of low-loss,low-dielectric constant superstrate can further reduce the contribution of superficial tissue layers in the received thermal noise. Several probe types are designed using a full-wave electromagnetic simulator, with a goal of maximizing the power reception from deep tissue layers. The designs are validated with a second software tool and various measurements. A stable, narrow-band, and highly sensitive radiometer is developed, enabling the device to operate in a non-shielded RF environment.To use the microwave thermometer in a RF congested environment, not only narrow-band probe and radiometers are used but an additional probe is introduced for observing the environmental interference. By applying an adaptive filter, the effect of RFI is mitigated in long-term measurements. Several solid and liquid tissue phantoms, required for accurate modeling of the probe and human body interaction, are also developed. The concept of human body microwave thermometry is validated through several measurements on the single-layer and multiple-layer tissue phantoms as well as on the surface of the human body, specifically on the cheek where the internal temperature can easily be changed and independently measured with a thermocouple. Measurement results prove the capability of the device in tracking the temperature of buried tissue layer phantoms to within 0.2K, as well as monitoring internal human body temperature.

A Data Set of Human Body Movements for Physical Rehabilitation Exercises.

PubMed

Vakanski, Aleksandar; Jun, Hyung-Pil; Paul, David; Baker, Russell

2018-03-01

The article presents University of Idaho - Physical Rehabilitation Movement Data (UI-PRMD) - a publically available data set of movements related to common exercises performed by patients in physical rehabilitation programs. For the data collection, 10 healthy subjects performed 10 repetitions of different physical therapy movements, with a Vicon optical tracker and a Microsoft Kinect sensor used for the motion capturing. The data are in a format that includes positions and angles of full-body joints. The objective of the data set is to provide a basis for mathematical modeling of therapy movements, as well as for establishing performance metrics for evaluation of patient consistency in executing the prescribed rehabilitation exercises.

Small Patch Antennas for UWB Wireless Body Area Network

NASA Astrophysics Data System (ADS)

Klemm, M.; Tröster, G.

This paper presents the transient characteristics of an aperture-stacked patch antenna (ASPA) and its miniaturized version. These antennas were designed for ultra-wideband (UWB) body area network (BAN) applications, to operate within the 3 to 6 GHz frequency band. The APSA with large ground plane size has a planar dimensions 70 × 70 mm2, the smaller version has dimensions 32 × 26 mm2. The latest yields 85% reduction of the antenna surface. Time- and frequency-domain characteristics of these antennas were calculated in a transmission mode (Tx) and also in a complete, two-antenna (Tx-Rx) system. We have used 3 different waveforms to drive the antenna: gaussian pulse (duration-250 ps), monocycle pulse (duration-300 ps) and defined wavelet (duration-650 ps). The received pulses have very similar shapes (fidelity >90%), but they differ in the voltage amplitudes. Results show that the highest received voltage (best transmission efficiency) is achieved for the pulse with the closest spectrum to the antenna's transfer function characteristic. In order to disclose the effects of the human body proximity, two body models were built and full-wave FDTD method was employed to carry out the simulations. Significant changes of the UWB antenna performance when close to the body were identified. The most important effects are the seriously decreased radiation efficiency (16 to 34%) and different (from that in a free space) shape of the antenna transfer function. The first one can have the impact on low power implementations of UWB wearable radios; the second one discloses possible influence on the UWB systems design (especially for template receivers). The impact of the human body on antenna characteristics was identified to be a key factor in UWB body-worn antenna design.

Odorant receptor-based discovery of natural repellents of human lice.

PubMed

Pelletier, Julien; Xu, Pingxi; Yoon, Kyong S; Clark, John M; Leal, Walter S

2015-11-01

The body louse, Pediculus humanus humanus, is an obligate blood-feeding ectoparasite and an important insect vector that mediates the transmission of diseases to humans. The analysis of the body louse genome revealed a drastic reduction of the chemosensory gene repertoires when compared to other insects, suggesting specific olfactory adaptations to host specialization and permanent parasitic lifestyle. Here, we present for the first time functional evidence for the role of odorant receptors (ORs) in this insect, with the objective to gain insight into the chemical ecology of this vector. We identified seven putative full-length ORs, in addition to the odorant receptor co-receptor (Orco), and expressed four of them in the Xenopus laevis oocytes system. When screened with a panel of ecologically-relevant odorants, PhumOR2 responded to a narrow set of compounds. At the behavior level, both head and body lice were repelled by the physiologically-active chemicals. This study presents the first evidence of the OR pathway being functional in lice and identifies PhumOR2 as a sensitive receptor of natural repellents that could be used to develop novel efficient molecules to control these insects. Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

Preliminary Upper Estimate of Peak Currents in Transcranial Magnetic Stimulation at Distant Locations from a TMS Coil

PubMed Central

Makarov, Sergey N.; Yanamadala, Janakinadh; Piazza, Matthew W.; Helderman, Alex M.; Thang, Niang S.; Burnham, Edward H.; Pascual-Leone, Alvaro

2016-01-01

Goals Transcranial magnetic stimulation (TMS) is increasingly used as a diagnostic and therapeutic tool for numerous neuropsychiatric disorders. The use of TMS might cause whole-body exposure to undesired induced currents in patients and TMS operators. The aim of the present study is to test and justify a simple analytical model known previously, which may be helpful as an upper estimate of eddy current density at a particular distant observation point for any body composition and any coil setup. Methods We compare the analytical solution with comprehensive adaptive mesh refinement-based FEM simulations of a detailed full-body human model, two coil types, five coil positions, about 100,000 observation points, and two distinct pulse rise times, thus providing a representative number of different data sets for comparison, while also using other numerical data. Results Our simulations reveal that, after a certain modification, the analytical model provides an upper estimate for the eddy current density at any location within the body. In particular, it overestimates the peak eddy currents at distant locations from a TMS coil by a factor of 10 on average. Conclusion The simple analytical model tested in the present study may be valuable as a rapid method to safely estimate levels of TMS currents at different locations within a human body. Significance At present, safe limits of general exposure to TMS electric and magnetic fields are an open subject, including fetal exposure for pregnant women. PMID:26685221

Human body and head characteristics as a communication medium for Body Area Network.

PubMed

Kifle, Yonatan; Hun-Seok Kim; Yoo, Jerald

2015-01-01

An in-depth investigation of the Body Channel Communication (BCC) under the environment set according to the IEEE 802.15.6 Body Area Network (BAN) standard is conducted to observe and characterize the human body as a communication medium. A thorough measurement of the human head as part of the human channel is also carried out. Human forehead, head to limb, and ear to ear channel is characterized. The channel gain of the human head follows the same bandpass profile of the human torso and limbs with the maximum channel gain occurring at 35MHz. The human body channel gain distribution histogram at given frequencies, while all the other parameters are held constant, exhibits a maximum variation of 2.2dB in the channel gain at the center frequency of the bandpass channel gain profile.

Anatomical and metabolic small-animal whole-body imaging using ring-shaped confocal photoacoustic computed tomography

NASA Astrophysics Data System (ADS)

Xia, Jun; Chatni, Muhammad; Maslov, Konstantin; Wang, Lihong V.

2013-03-01

Due to the wide use of animals for human disease studies, small animal whole-body imaging plays an increasingly important role in biomedical research. Currently, none of the existing imaging modalities can provide both anatomical and glucose metabolic information, leading to higher costs of building dual-modality systems. Even with image coregistration, the spatial resolution of the metabolic imaging modality is not improved. We present a ring-shaped confocal photoacoustic computed tomography (RC-PACT) system that can provide both assessments in a single modality. Utilizing the novel design of confocal full-ring light delivery and ultrasound transducer array detection, RC-PACT provides full-view cross-sectional imaging with high spatial resolution. Scanning along the orthogonal direction provides three-dimensional imaging. While the mouse anatomy was imaged with endogenous hemoglobin contrast, the glucose metabolism was imaged with a near-infrared dye-labeled 2-deoxyglucose. Through mouse tumor models, we demonstrate that RC-PACT may be a paradigm shifting imaging method for preclinical research.

Human microcephaly protein RTTN interacts with STIL and is required to build full-length centrioles.

PubMed

Chen, Hsin-Yi; Wu, Chien-Ting; Tang, Chieh-Ju C; Lin, Yi-Nan; Wang, Won-Jing; Tang, Tang K

2017-08-15

Mutations in many centriolar protein-encoding genes cause primary microcephaly. Using super-resolution and electron microscopy, we find that the human microcephaly protein, RTTN, is recruited to the proximal end of the procentriole at early S phase, and is located at the inner luminal walls of centrioles. Further studies demonstrate that RTTN directly interacts with STIL and acts downstream of STIL-mediated centriole assembly. CRISPR/Cas9-mediated RTTN gene knockout in p53-deficient cells induce amplification of primitive procentriole bodies that lack the distal-half centriolar proteins, POC5 and POC1B. Additional analyses show that RTTN serves as an upstream effector of CEP295, which mediates the loading of POC1B and POC5 to the distal-half centrioles. Interestingly, the naturally occurring microcephaly-associated mutant, RTTN (A578P), shows a low affinity for STIL binding and blocks centriole assembly. These findings reveal that RTTN contributes to building full-length centrioles and illuminate the molecular mechanism through which the RTTN (A578P) mutation causes primary microcephaly.Mutations in many centriolar protein-encoding genes cause primary microcephaly. Here the authors show that human microcephaly protein RTTN directly interacts with STIL and acts downstream of STIL-mediated centriole assembly, contributing to building full-length centrioles.

Neural Integration of Information Specifying Human Structure from Form, Motion, and Depth

PubMed Central

Jackson, Stuart; Blake, Randolph

2010-01-01

Recent computational models of biological motion perception operate on ambiguous two-dimensional representations of the body (e.g., snapshots, posture templates) and contain no explicit means for disambiguating the three-dimensional orientation of a perceived human figure. Are there neural mechanisms in the visual system that represent a moving human figure’s orientation in three dimensions? To isolate and characterize the neural mechanisms mediating perception of biological motion, we used an adaptation paradigm together with bistable point-light (PL) animations whose perceived direction of heading fluctuates over time. After exposure to a PL walker with a particular stereoscopically defined heading direction, observers experienced a consistent aftereffect: a bistable PL walker, which could be perceived in the adapted orientation or reversed in depth, was perceived predominantly reversed in depth. A phase-scrambled adaptor produced no aftereffect, yet when adapting and test walkers differed in size or appeared on opposite sides of fixation aftereffects did occur. Thus, this heading direction aftereffect cannot be explained by local, disparity-specific motion adaptation, and the properties of scale and position invariance imply higher-level origins of neural adaptation. Nor is disparity essential for producing adaptation: when suspended on top of a stereoscopically defined, rotating globe, a context-disambiguated “globetrotter” was sufficient to bias the bistable walker’s direction, as were full-body adaptors. In sum, these results imply that the neural signals supporting biomotion perception integrate information on the form, motion, and three-dimensional depth orientation of the moving human figure. Models of biomotion perception should incorporate mechanisms to disambiguate depth ambiguities in two-dimensional body representations. PMID:20089892

Passive drag reduction using full-body swimsuits: the role of body position.

PubMed

Cortesi, Matteo; Fantozzi, Silvia; Di Michele, Rocco; Zamparo, Paola; Gatta, Giorgio

2014-11-01

This study aimed to analyze whether using full-body swimsuits affects the swimmer's body alignment and to what extent changes in the body position are responsible of the passive drag (Dp) reduction experienced by the swimmers when using these swimsuits. Fourteen swimmers performed 20-m towing trials using a full-body synthetic rubber swimsuit, a full-body textile swimsuit, a traditional brief swimsuit, and a traditional brief swimsuit with a pull buoy. In all trials, the speed-specific drag (k = Dp per v), the trunk incline (TI), and the lower limbs incline (LI) were determined. In comparison with both conditions in which a full-body swimsuit was not used, k was significantly lower when using the rubber swimsuit (-8.4 and -12.2% vs. the brief swimsuit with and without pull bouy, respectively), and the textile swimsuit (-6.9 and -10.8% vs. the brief swimsuit with and without pull bouy, respectively). No differences in TI were observed among conditions, whereas LI was significantly higher when using the rubber swimsuit or the brief swimsuit with pull buoy than when using the traditional brief swimsuit. A linear mixed model showed that k can be reduced by increasing LI (that is lifting the lower limbs), by decreasing TI (that is keeping the trunk more horizontal), and by using either the rubber or textile full-body swimsuit rather than the traditional brief swimsuit. In conclusion, full-body swimsuits involve a reduction of a swimmer's passive drag caused by intrinsic properties related to the "material composition" of the swimsuits and also influenced by changes in the swimmer's body position.

Informed Consent, Body Property, and Self-Sovereignty.

PubMed

Rao, Radhika

2016-09-01

Recent cases involving biosamples taken from indigenous tribes and newborn babies reveal the emptiness of informed consent. This venerable doctrine often functions as a charade, a collective fiction which thinly masks the uncomfortable fact that the subjects of human research are not actually afforded full information regarding the types of research that may be contemplated, nor do they provide meaningful consent. But if informed consent fails to provide adequate protection to the donors of biological materials, why not turn to principles of property law? Property is power, yet current law permits everyone except for those who donate biological materials to possess property rights. The reluctance to invoke property probably stems from fears of resurrecting slavery and the commodification of human beings. But ironically, avoidance of property transforms the subjects of human research into objects that can be owned only by others, resulting in new forms of oppression and exploitation. Human research subjects are autonomous individuals who should not only possess the power to contribute their biological materials, but also the right to help control the course of research, and to share in the resulting benefits or profits. Conferring body property might enable research subjects to regain power and a measure of self-sovereignty. © 2016 American Society of Law, Medicine & Ethics.

Supersonic full-potential methods for missile body analysis

NASA Technical Reports Server (NTRS)

Pittman, James L.

1992-01-01

Accounts are presented of representative applications to missile bodies of arbitrary shape of methods based on the steady form of the full potential equation. The NCOREL and SIMP full-potential codes are compared, and their results are evaluated for the cases of an arrow wing and a wing-body configuration. Attention is given to the effect of cross-sectional and longitudinal geometries. Comparisons of surface pressure and longitudinal force and moment data for circular and elliptic bodies have shown that the full-potential methods yielded excellent results in attached-flow conditions. Results are presented for a conical star body, waveriders, the Shuttle Orbiter, and a highly swept wing-body cruising at Mach 4.

Problem: Thirst, Drinking Behavior, and Involuntary Dehydration

NASA Technical Reports Server (NTRS)

Greenleaf, John E.

1992-01-01

The phenomenon of involuntary dehydration, the delay in full restoration of a body water deficit by drinking, has been described extensively but relatively little is known about its physiological mechanism. It occurs primarily in humans when they are exposed to various stresses including exercise, environmental heat and cold, altitude, water immersion, dehydration, and perhaps microgravity, singly and in various combinations. The level of involuntary dehydration is approximately proportional to the degree of total stress imposed on the body. Involuntary dehydration appears to be controlled by more than one factor including social customs that influence what is consumed, the capacity and rate of fluid absorption from the gastrointestinal system, the level of cellular hydration involving the osmotic-vasopressin interaction with sensitive cells or structures in the central nervous system, and, to a lesser extent, hypovolemic-angiotensin II stimuli. Since humans drink when there is no apparent physiological stimulus, the psychological component should always be considered when investigating the total mechanisms for drinking.

CRUX: A compliant robotic upper-extremity exosuit for lightweight, portable, multi-joint muscular augmentation.

PubMed

Lessard, Steven; Pansodtee, Pattawong; Robbins, Ash; Baltaxe-Admony, Leya Breanna; Trombadore, James M; Teodorescu, Mircea; Agogino, Adrian; Kurniawan, Sri

2017-07-01

Wearable robots can potentially offer their users enhanced stability and strength. These augmentations are ideally designed to actuate harmoniously with the user's movements and provide extra force as needed. The creation of such robots, however, is particularly challenging due to the underlying complexity of the human body. In this paper, we present a compliant, robotic exosuit for upper extremities called CRUX. This exosuit, inspired by tensegrity models of the human arm, features a lightweight (1.3 kg), flexible multi-joint design for portable augmentation. We also illustrate how CRUX maintains the full range of motion of the upper-extremities for its users while providing multi-DoF strength amplification to the major muscles of the arm, as evident by tracking the heart rate of an individual exercising said arm. Exosuits such as CRUX may be useful in physical therapy and in extreme environments where users are expected to exert their bodies to the fullest extent.

TOPICAL REVIEW: Modelling the interaction of electromagnetic fields (10 MHz 10 GHz) with the human body: methods and applications

NASA Astrophysics Data System (ADS)

Hand, J. W.

2008-08-01

Numerical modelling of the interaction between electromagnetic fields (EMFs) and the dielectrically inhomogeneous human body provides a unique way of assessing the resulting spatial distributions of internal electric fields, currents and rate of energy deposition. Knowledge of these parameters is of importance in understanding such interactions and is a prerequisite when assessing EMF exposure or when assessing or optimizing therapeutic or diagnostic medical applications that employ EMFs. In this review, computational methods that provide this information through full time-dependent solutions of Maxwell's equations are summarized briefly. This is followed by an overview of safety- and medical-related applications where modelling has contributed significantly to development and understanding of the techniques involved. In particular, applications in the areas of mobile communications, magnetic resonance imaging, hyperthermal therapy and microwave radiometry are highlighted. Finally, examples of modelling the potentially new medical applications of recent technologies such as ultra-wideband microwaves are discussed.

Movement Contributes to Infants' Recognition of the Human Form

ERIC Educational Resources Information Center

Christie, Tamara; Slaughter, Virginia

2010-01-01

Three experiments demonstrate that biological movement facilitates young infants' recognition of the whole human form. A body discrimination task was used in which 6-, 9-, and 12-month-old infants were habituated to typical human bodies and then shown scrambled human bodies at the test. Recovery of interest to the scrambled bodies was observed in…

Cold-Water Immersion for Hyperthermic Humans Wearing American Football Uniforms.

PubMed

Miller, Kevin C; Swartz, Erik E; Long, Blaine C

2015-08-01

Current treatment recommendations for American football players with exertional heatstroke are to remove clothing and equipment and immerse the body in cold water. It is unknown if wearing a full American football uniform during cold-water immersion (CWI) impairs rectal temperature (Trec) cooling or exacerbates hypothermic afterdrop. To determine the time to cool Trec from 39.5°C to 38.0°C while participants wore a full American football uniform or control uniform during CWI and to determine the uniform's effect on Trec recovery postimmersion. Crossover study. Laboratory. A total of 18 hydrated, physically active, unacclimated men (age = 22 ± 3 years, height = 178.8 ± 6.8 cm, mass = 82.3 ± 12.6 kg, body fat = 13% ± 4%, body surface area = 2.0 ± 0.2 m(2)). Participants wore the control uniform (undergarments, shorts, crew socks, tennis shoes) or full uniform (control plus T-shirt; tennis shoes; jersey; game pants; padding over knees, thighs, and tailbone; helmet; and shoulder pads). They exercised (temperature approximately 40°C, relative humidity approximately 35%) until Trec reached 39.5°C. They removed their T-shirts and shoes and were then immersed in water (approximately 10°C) while wearing each uniform configuration; time to cool Trec to 38.0°C (in minutes) was recorded. We measured Trec (°C) every 5 minutes for 30 minutes after immersion. Time to cool from 39.5°C to 38.0°C and Trec. The Trec cooled to 38.0°C in 6.19 ± 2.02 minutes in full uniform and 8.49 ± 4.78 minutes in control uniform (t17 = -2.1, P = .03; effect size = 0.48) corresponding to cooling rates of 0.28°C·min(-1) ± 0.12°C·min(-1) in full uniform and 0.23°C·min(-1) ± 0.11°C·min(-1) in control uniform (t17 = 1.6, P = .07, effect size = 0.44). The Trec postimmersion recovery did not differ between conditions over time (F1,17 = 0.6, P = .59). We speculate that higher skin temperatures before CWI, less shivering, and greater conductive cooling explained the faster cooling in full uniform. Cooling rates were considered ideal when the full uniform was worn during CWI, and wearing the full uniform did not cause a greater postimmersion hypothermic afterdrop. Clinicians may immerse football athletes with hyperthermia wearing a full uniform without concern for negatively affecting body-core cooling.

Statistical multi-path exposure method for assessing the whole-body SAR in a heterogeneous human body model in a realistic environment.

PubMed

Vermeeren, Günter; Joseph, Wout; Martens, Luc

2013-04-01

Assessing the whole-body absorption in a human in a realistic environment requires a statistical approach covering all possible exposure situations. This article describes the development of a statistical multi-path exposure method for heterogeneous realistic human body models. The method is applied for the 6-year-old Virtual Family boy (VFB) exposed to the GSM downlink at 950 MHz. It is shown that the whole-body SAR does not differ significantly over the different environments at an operating frequency of 950 MHz. Furthermore, the whole-body SAR in the VFB for multi-path exposure exceeds the whole-body SAR for worst-case single-incident plane wave exposure by 3.6%. Moreover, the ICNIRP reference levels are not conservative with the basic restrictions in 0.3% of the exposure samples for the VFB at the GSM downlink of 950 MHz. The homogeneous spheroid with the dielectric properties of the head suggested by the IEC underestimates the absorption compared to realistic human body models. Moreover, the variation in the whole-body SAR for realistic human body models is larger than for homogeneous spheroid models. This is mainly due to the heterogeneity of the tissues and the irregular shape of the realistic human body model compared to homogeneous spheroid human body models. Copyright © 2012 Wiley Periodicals, Inc.

Full-Body CT Scans - What You Need to Know

MedlinePlus

... Medical Imaging Medical X-ray Imaging Full-Body CT Scans - What You Need to Know Share Tweet ... new service for health-conscious people: "Whole-body CT screening." This typically involves scanning the body from ...

Real-time "x-ray vision" for healthcare simulation: an interactive projective overlay system to enhance intubation training and other procedural training.

PubMed

Samosky, Joseph T; Baillargeon, Emma; Bregman, Russell; Brown, Andrew; Chaya, Amy; Enders, Leah; Nelson, Douglas A; Robinson, Evan; Sukits, Alison L; Weaver, Robert A

2011-01-01

We have developed a prototype of a real-time, interactive projective overlay (IPO) system that creates augmented reality display of a medical procedure directly on the surface of a full-body mannequin human simulator. These images approximate the appearance of both anatomic structures and instrument activity occurring within the body. The key innovation of the current work is sensing the position and motion of an actual device (such as an endotracheal tube) inserted into the mannequin and using the sensed position to control projected video images portraying the internal appearance of the same devices and relevant anatomic structures. The images are projected in correct registration onto the surface of the simulated body. As an initial practical prototype to test this technique we have developed a system permitting real-time visualization of the intra-airway position of an endotracheal tube during simulated intubation training.

The Human Oral Microbiome Database: a web accessible resource for investigating oral microbe taxonomic and genomic information

PubMed Central

Chen, Tsute; Yu, Wen-Han; Izard, Jacques; Baranova, Oxana V.; Lakshmanan, Abirami; Dewhirst, Floyd E.

2010-01-01

The human oral microbiome is the most studied human microflora, but 53% of the species have not yet been validly named and 35% remain uncultivated. The uncultivated taxa are known primarily from 16S rRNA sequence information. Sequence information tied solely to obscure isolate or clone numbers, and usually lacking accurate phylogenetic placement, is a major impediment to working with human oral microbiome data. The goal of creating the Human Oral Microbiome Database (HOMD) is to provide the scientific community with a body site-specific comprehensive database for the more than 600 prokaryote species that are present in the human oral cavity based on a curated 16S rRNA gene-based provisional naming scheme. Currently, two primary types of information are provided in HOMD—taxonomic and genomic. Named oral species and taxa identified from 16S rRNA gene sequence analysis of oral isolates and cloning studies were placed into defined 16S rRNA phylotypes and each given unique Human Oral Taxon (HOT) number. The HOT interlinks phenotypic, phylogenetic, genomic, clinical and bibliographic information for each taxon. A BLAST search tool is provided to match user 16S rRNA gene sequences to a curated, full length, 16S rRNA gene reference data set. For genomic analysis, HOMD provides comprehensive set of analysis tools and maintains frequently updated annotations for all the human oral microbial genomes that have been sequenced and publicly released. Oral bacterial genome sequences, determined as part of the Human Microbiome Project, are being added to the HOMD as they become available. We provide HOMD as a conceptual model for the presentation of microbiome data for other human body sites. Database URL: http://www.homd.org PMID:20624719

Developmental changes in emotion recognition from full-light and point-light displays of body movement.

PubMed

Ross, Patrick D; Polson, Louise; Grosbras, Marie-Hélène

2012-01-01

To date, research on the development of emotion recognition has been dominated by studies on facial expression interpretation; very little is known about children's ability to recognize affective meaning from body movements. In the present study, we acquired simultaneous video and motion capture recordings of two actors portraying four basic emotions (Happiness Sadness, Fear and Anger). One hundred and seven primary and secondary school children (aged 4-17) and 14 adult volunteers participated in the study. Each participant viewed the full-light and point-light video clips and was asked to make a forced-choice as to which emotion was being portrayed. As a group, children performed worse than adults for both point-light and full-light conditions. Linear regression showed that both age and lighting condition were significant predictors of performance in children. Using piecewise regression, we found that a bilinear model with a steep improvement in performance until 8.5 years of age, followed by a much slower improvement rate through late childhood and adolescence best explained the data. These findings confirm that, like for facial expression, adolescents' recognition of basic emotions from body language is not fully mature and seems to follow a non-linear development. This is in line with observations of non-linear developmental trajectories for different aspects of human stimuli processing (voices and faces), perhaps suggesting a shift from one perceptual or cognitive strategy to another during adolescence. These results have important implications to understanding the maturation of social cognition.

Contributions of visual and embodied expertise to body perception.

PubMed

Reed, Catherine L; Nyberg, Andrew A; Grubb, Jefferson D

2012-01-01

Recent research has demonstrated that our perception of the human body differs from that of inanimate objects. This study investigated whether the visual perception of the human body differs from that of other animate bodies and, if so, whether that difference could be attributed to visual experience and/or embodied experience. To dissociate differential effects of these two types of expertise, inversion effects (recognition of inverted stimuli is slower and less accurate than recognition of upright stimuli) were compared for two types of bodies in postures that varied in typicality: humans in human postures (human-typical), humans in dog postures (human-atypical), dogs in dog postures (dog-typical), and dogs in human postures (dog-atypical). Inversion disrupts global configural processing. Relative changes in the size and presence of inversion effects reflect changes in visual processing. Both visual and embodiment expertise predict larger inversion effects for human over dog postures because we see humans more and we have experience producing human postures. However, our design that crosses body type and typicality leads to distinct predictions for visual and embodied experience. Visual expertise predicts an interaction between typicality and orientation: greater inversion effects should be found for typical over atypical postures regardless of body type. Alternatively, embodiment expertise predicts a body, typicality, and orientation interaction: larger inversion effects should be found for all human postures but only for atypical dog postures because humans can map their bodily experience onto these postures. Accuracy data supported embodiment expertise with the three-way interaction. However, response-time data supported contributions of visual expertise with larger inversion effects for typical over atypical postures. Thus, both types of expertise affect the visual perception of bodies.

[Research progress on free radicals in human body].

PubMed

Wang, Q B; Xu, F P; Wei, C X; Peng, J; Dong, X D

2016-08-10

Free radicals are the intermediates of metabolism, widely exist in the human bodies. Under normal circumstances, the free radicals play an important role in the metabolic process on human body, cell signal pathway, gene regulation, induction of cell proliferation and apoptosis, so as to maintain the normal growth and development of human body and to inhibit the growth of bacteria, virus and cancer. However, when organic lesion occurs affected by external factors or when equilibrium of the free radicals is tipped in the human body, the free radicals will respond integratedly with lipids, protein or nucleic acid which may jeopardize the health of human bodies. This paper summarizes the research progress of the free radicals conducted in recent years, in relations to the perspective of the types, origins, test methods of the free radicals and their relationship with human's health. In addition, the possible mechanisms of environmental pollutants (such as polycyclic aromatic hydrocarbons) mediating oxidative stress and free radicals scavenging in the body were also summarized.

A simple strategy for the purification of native recombinant full-length human RPL10 protein from inclusion bodies.

PubMed

Pereira, Larissa M; Silva, Luana R; Alves, Joseane F; Marin, Nélida; Silva, Flavio Sousa; Morganti, Ligia; Silva, Ismael D C G; Affonso, Regina

2014-09-01

The L10 ribosomal protein (RPL10) plays a role in the binding of the 60 S and 40 S ribosomal subunits and in mRNA translation. The evidence indicates that RPL10 also has multiple extra-ribosomal functions, including tumor suppression. Recently, the presence of RPL10 in prostate and ovarian cancers was evaluated, and it was demonstrated to be associated with autistic disorders and premature ovarian failure. In the present work, we successfully cloned and expressed full-length human RPL10 (hRPL10) protein and isolated inclusion bodies containing this protein that had formed under mild growth conditions. The culture produced 376mg of hRPL10 protein per liter of induced bacterial culture, of which 102.4mg was present in the soluble fraction, and 25.6mg was recovered at approximately 94% purity. These results were obtained using a two-step process of non-denaturing protein extraction from pelleted inclusion bodies. We studied the characteristics of this protein using circular dichroism spectroscopy and by monitoring the changes induced by the presence or absence of zinc ions using fluorescence spectrometry. The results demonstrated that the protein obtained using these non-conventional methods retained its secondary and tertiary structure. The conformational changes induced by the incorporation of zinc suggested that this protein could interact with Jun or the SH3 domain of c-yes. The results suggested that the strategy used to obtain hRPL10 is simple and could be applied to obtaining other proteins that are susceptible to degradation. Copyright © 2014 Elsevier Inc. All rights reserved.

Predictive Simulations of Neuromuscular Coordination and Joint-Contact Loading in Human Gait.

PubMed

Lin, Yi-Chung; Walter, Jonathan P; Pandy, Marcus G

2018-04-18

We implemented direct collocation on a full-body neuromusculoskeletal model to calculate muscle forces, ground reaction forces and knee contact loading simultaneously for one cycle of human gait. A data-tracking collocation problem was solved for walking at the normal speed to establish the practicality of incorporating a 3D model of articular contact and a model of foot-ground interaction explicitly in a dynamic optimization simulation. The data-tracking solution then was used as an initial guess to solve predictive collocation problems, where novel patterns of movement were generated for walking at slow and fast speeds, independent of experimental data. The data-tracking solutions accurately reproduced joint motion, ground forces and knee contact loads measured for two total knee arthroplasty patients walking at their preferred speeds. RMS errors in joint kinematics were < 2.0° for rotations and < 0.3 cm for translations while errors in the model-computed ground-reaction and knee-contact forces were < 0.07 BW and < 0.4 BW, respectively. The predictive solutions were also consistent with joint kinematics, ground forces, knee contact loads and muscle activation patterns measured for slow and fast walking. The results demonstrate the feasibility of performing computationally-efficient, predictive, dynamic optimization simulations of movement using full-body, muscle-actuated models with realistic representations of joint function.

Forensic DNA typing from teeth using demineralized root tips.

PubMed

Corrêa, Heitor Simões Dutra; Pedro, Fabio Luis Miranda; Volpato, Luiz Evaristo Ricci; Pereira, Thiago Machado; Siebert Filho, Gilberto; Borges, Álvaro Henrique

2017-11-01

Teeth are widely used samples in forensic human genetic identification due to their persistence and practical sampling and processing. Their processing, however, has changed very little in the last 20 years, usually including powdering or pulverization of the tooth. The objective of this study was to present demineralized root tips as DNA sources while, at the same time, not involving powdering the samples or expensive equipment for teeth processing. One to five teeth from each of 20 unidentified human bodies recovered from midwest Brazil were analyzed. Whole teeth were demineralized in EDTA solution with daily solution change. After a maximum of approximately seven days, the final millimeters of the root tip was excised. This portion of the sample was used for DNA extraction through a conventional organic protocol. DNA quantification and STR amplification were performed using commercial kits followed by capillary electrophoresis on 3130 or 3500 genetic analyzers. For 60% of the unidentified bodies (12 of 20), a full genetic profile was obtained from the extraction of the first root tip. By the end of the analyses, full genetic profiles were obtained for 85% of the individuals studied, of which 80% were positively identified. This alternative low-tech approach for postmortem teeth processing is capable of extracting DNA in sufficient quantity and quality for forensic casework, showing that root tips are viable nuclear DNA sources even after demineralization. Copyright © 2017 Elsevier B.V. All rights reserved.

Microwave non-contact imaging of subcutaneous human body tissues.

PubMed

Kletsov, Andrey; Chernokalov, Alexander; Khripkov, Alexander; Cho, Jaegeol; Druchinin, Sergey

2015-10-01

A small-size microwave sensor is developed for non-contact imaging of a human body structure in 2D, enabling fitness and health monitoring using mobile devices. A method for human body tissue structure imaging is developed and experimentally validated. Subcutaneous fat tissue reconstruction depth of up to 70 mm and maximum fat thickness measurement error below 2 mm are demonstrated by measurements with a human body phantom and human subjects. Electrically small antennas are developed for integration of the microwave sensor into a mobile device. Usability of the developed microwave sensor for fitness applications, healthcare, and body weight management is demonstrated.

In-to-out body path loss for wireless radio frequency capsule endoscopy in a human body.

PubMed

Vermeeren, G; Tanghe, E; Thielens, A; Martens, L; Joseph, W

2016-08-01

Physical-layer characterization is important for design of in-to-out body communication for wireless body area networks (WBANs). This paper numerically investigates the path loss of an in-to-out body radio frequency (RF) wireless link between an endoscopy capsule and a receiver outside the body using a 3D electromagnetic solver. A spiral antenna in the endoscopy capsule is tuned to operate in the Medical Implant Communication Service (MICS) band at 402 MHz, accounting for the properties of the human body. The influence of misalignment, rotation of the capsule, and human body model are investigated. Semi-empirical path loss models for various homogeneous tissues and 3D realistic human body models are provided for manufacturers to evaluate the performance of in-to-out-body WBAN systems.

The effects of a transcontinental flight on markers of coagulation and fibrinolysis in healthy men after vigorous physical activity.

PubMed

Kupchak, Brian R; Kraemer, William J; Hooper, David R; Saenz, Cathy; Dulkis, Lexie L; Secola, Paul J; Brown, Lee E; Galpin, Andrew J; Coburn, Jared W; DuPont, William H; Caldwell, Lydia K; Volek, Jeff S; Maresh, Carl M

2017-01-01

Athletes and military service members are known to undergo strenuous exercise and sometimes have to take long haul flights soon afterwards; however, its combined effect on many physiological functions is relatively unknown. Therefore, we examined the combined effects of a full-body muscle-damaging workout and transcontinental flight on coagulation and fibrinolysis in healthy, resistance trained men. We also determined the efficacy of a full-body compression garment in limiting their coagulation responses. Nineteen healthy, resistance trained men flew from Connecticut (CT) to California (CA), performed a full-body muscle-damaging workout and then flew back to CT. Ten participants wore full-body compression garments (FCG) for the duration of both flights and during all other portions of the study except during workouts and blood draws, when they wore loose clothing. Nine controls wore loose clothing (CON) throughout the study. Blood samples were collected at 16 h and 3 h before the initial flight from CT, immediately after landing in CA, immediately before and immediately after the full-body workout in CA, immediately after landing in CT, and at 29 h after landing in CT. Plasma markers of coagulation included activated partial thromboplastin time (aPTT), prothrombin fragment 1+2 (PTF 1+2) and thrombin ant-thrombin (TAT). Markers of the fibrinolytic system included the tissue plasmigen activator (tPA), plasminogen activator inhibitor-1 (PAI-1) and D-Dimer. Both FCG and CON groups exhibited a faster aPTT after the full-body workout compared to all other time points.  Thrombin generation markers, TAT and PTF 1+2, increased significantly after the full-body workout and immediately after landing in CT. Additionally, tPA increased after the full-body workout, while PAI-1 increased before the flight to CA, after the full-body workout, and just after landing in CT. The D-Dimer significantly increased after the full-body workout and at 29 h post-flight in both groups. Between groups, aPTT was significantly faster and TAT elevated with the CON group at 29 h post-flight. Also, PAI-1 demonstrated higher concentrations immediately after landing in CT for the CON group. A full-body muscle-damaging workout in conjunction with a trans-continental flight activated the coagulation and fibrinolytic systems. Additionally, wearing a full-body compression garment may limit coagulation following a workout through the recovery period.

Neural correlates of human body perception.

PubMed

Aleong, Rosanne; Paus, Tomás

2010-03-01

The objective of this study was to investigate potential sex differences in the neural response to human bodies using fMRI carried out in healthy young adults. We presented human bodies in a block-design experiment to identify body-responsive regions of the brain, namely, extrastriate body area (EBA) and fusiform body area (FBA). In a separate event-related "adaptation" experiment, carried out in the same group of subjects, we presented sets of four human bodies of varying body size and shape. Varying levels of body morphing were introduced to assess the degree of morphing required for adaptation release. Analysis of BOLD signal in the block-design experiment revealed significant Sex x Hemisphere interactions in the EBA and the FBA responses to human bodies. Only women showed greater BOLD response to bodies in the right hemisphere compared with the left hemisphere for both EBA and FBA. The BOLD response in right EBA was higher in women compared with men. In the adaptation experiment, greater right versus left hemisphere response for EBA and FBA was also identified among women but not men. These findings are particularly novel in that they address potential sex differences in the lateralization of EBA and FBA responses to human body images. Although previous studies have found some degree of right hemisphere dominance in body perception, our results suggest that such a functional lateralization may differ between men and women.

Three-dimensional data-tracking dynamic optimization simulations of human locomotion generated by direct collocation.

PubMed

Lin, Yi-Chung; Pandy, Marcus G

2017-07-05

The aim of this study was to perform full-body three-dimensional (3D) dynamic optimization simulations of human locomotion by driving a neuromusculoskeletal model toward in vivo measurements of body-segmental kinematics and ground reaction forces. Gait data were recorded from 5 healthy participants who walked at their preferred speeds and ran at 2m/s. Participant-specific data-tracking dynamic optimization solutions were generated for one stride cycle using direct collocation in tandem with an OpenSim-MATLAB interface. The body was represented as a 12-segment, 21-degree-of-freedom skeleton actuated by 66 muscle-tendon units. Foot-ground interaction was simulated using six contact spheres under each foot. The dynamic optimization problem was to find the set of muscle excitations needed to reproduce 3D measurements of body-segmental motions and ground reaction forces while minimizing the time integral of muscle activations squared. Direct collocation took on average 2.7±1.0h and 2.2±1.6h of CPU time, respectively, to solve the optimization problems for walking and running. Model-computed kinematics and foot-ground forces were in good agreement with corresponding experimental data while the calculated muscle excitation patterns were consistent with measured EMG activity. The results demonstrate the feasibility of implementing direct collocation on a detailed neuromusculoskeletal model with foot-ground contact to accurately and efficiently generate 3D data-tracking dynamic optimization simulations of human locomotion. The proposed method offers a viable tool for creating feasible initial guesses needed to perform predictive simulations of movement using dynamic optimization theory. The source code for implementing the model and computational algorithm may be downloaded at http://simtk.org/home/datatracking. Copyright © 2017 Elsevier Ltd. All rights reserved.

An alternative pluripotent state confers interspecies chimaeric competency

PubMed Central

Wu, Jun; Okamura, Daiji; Li, Mo; Suzuki, Keiichiro; Luo, Chongyuan; Ma, Li; He, Yupeng; Li, Zhongwei; Benner, Chris; Tamura, Isao; Krause, Marie N.; Nery, Joseph R.; Du, Tingting; Zhang, Zhuzhu; Hishida, Tomoaki; Takahashi, Yuta; Aizawa, Emi; Kim, Na Young; Lajara, Jeronimo; Guillen, Pedro; Campistol, Josep M.; Esteban, Concepcion Rodriguez; Ross, Pablo J.; Saghatelian, Alan; Ren, Bing; Ecker, Joseph R.; Belmonte, Juan Carlos Izpisua

2017-01-01

Pluripotency, the ability to generate any cell type of the body, is an evanescent attribute of embryonic cells. Transitory pluripotent cells can be captured at different time points during embryogenesis and maintained as embryonic stem cells or epiblast stem cells in culture. Since ontogenesis is a dynamic process in both space and time, it seems counterintuitive that these two temporal states represent the full spectrum of organismal pluripotency. Here we show that by modulating culture parameters, a stem-cell type with unique spatial characteristics and distinct molecular and functional features, designated as region-selective pluripotent stem cells (rsPSCs), can be efficiently obtained from mouse embryos and primate pluripotent stem cells, including humans. The ease of culturing and editing the genome of human rsPSCs offers advantages for regenerative medicine applications. The unique ability of human rsPSCs to generate post-implantation interspecies chimaeric embryos may facilitate our understanding of early human development and evolution. PMID:25945737

The Body That Speaks: Recombining Bodies and Speech Sources in Unscripted Face-to-Face Communication.

PubMed

Gillespie, Alex; Corti, Kevin

2016-01-01

This article examines advances in research methods that enable experimental substitution of the speaking body in unscripted face-to-face communication. A taxonomy of six hybrid social agents is presented by combining three types of bodies (mechanical, virtual, and human) with either an artificial or human speech source. Our contribution is to introduce and explore the significance of two particular hybrids: (1) the cyranoid method that enables humans to converse face-to-face through the medium of another person's body, and (2) the echoborg method that enables artificial intelligence to converse face-to-face through the medium of a human body. These two methods are distinct in being able to parse the unique influence of the human body when combined with various speech sources. We also introduce a new framework for conceptualizing the body's role in communication, distinguishing three levels: self's perspective on the body, other's perspective on the body, and self's perspective of other's perspective on the body. Within each level the cyranoid and echoborg methodologies make important research questions tractable. By conceptualizing and synthesizing these methods, we outline a novel paradigm of research on the role of the body in unscripted face-to-face communication.

The Body That Speaks: Recombining Bodies and Speech Sources in Unscripted Face-to-Face Communication

PubMed Central

Gillespie, Alex; Corti, Kevin

2016-01-01

This article examines advances in research methods that enable experimental substitution of the speaking body in unscripted face-to-face communication. A taxonomy of six hybrid social agents is presented by combining three types of bodies (mechanical, virtual, and human) with either an artificial or human speech source. Our contribution is to introduce and explore the significance of two particular hybrids: (1) the cyranoid method that enables humans to converse face-to-face through the medium of another person's body, and (2) the echoborg method that enables artificial intelligence to converse face-to-face through the medium of a human body. These two methods are distinct in being able to parse the unique influence of the human body when combined with various speech sources. We also introduce a new framework for conceptualizing the body's role in communication, distinguishing three levels: self's perspective on the body, other's perspective on the body, and self's perspective of other's perspective on the body. Within each level the cyranoid and echoborg methodologies make important research questions tractable. By conceptualizing and synthesizing these methods, we outline a novel paradigm of research on the role of the body in unscripted face-to-face communication. PMID:27660616

Evaluating morphometric body mass prediction equations with a juvenile human test sample: accuracy and applicability to small-bodied hominins.

PubMed

Walker, Christopher S; Yapuncich, Gabriel S; Sridhar, Shilpa; Cameron, Noël; Churchill, Steven E

2018-02-01

Body mass is an ecologically and biomechanically important variable in the study of hominin biology. Regression equations derived from recent human samples allow for the reasonable prediction of body mass of later, more human-like, and generally larger hominins from hip joint dimensions, but potential differences in hip biomechanics across hominin taxa render their use questionable with some earlier taxa (i.e., Australopithecus spp.). Morphometric prediction equations using stature and bi-iliac breadth avoid this problem, but their applicability to early hominins, some of which differ in both size and proportions from modern adult humans, has not been demonstrated. Here we use mean stature, bi-iliac breadth, and body mass from a global sample of human juveniles ranging in age from 6 to 12 years (n = 530 age- and sex-specific group annual means from 33 countries/regions) to evaluate the accuracy of several published morphometric prediction equations when applied to small humans. Though the body proportions of modern human juveniles likely differ from those of small-bodied early hominins, human juveniles (like fossil hominins) often differ in size and proportions from adult human reference samples and, accordingly, serve as a useful model for assessing the robustness of morphometric prediction equations. Morphometric equations based on adults systematically underpredict body mass in the youngest age groups and moderately overpredict body mass in the older groups, which fall in the body size range of adult Australopithecus (∼26-46 kg). Differences in body proportions, notably the ratio of lower limb length to stature, influence predictive accuracy. Ontogenetic changes in these body proportions likely influence the shift in prediction error (from under- to overprediction). However, because morphometric equations are reasonably accurate when applied to this juvenile test sample, we argue these equations may be used to predict body mass in small-bodied hominins, despite the potential for some error induced by differing body proportions and/or extrapolation beyond the original reference sample range. Copyright © 2017 Elsevier Ltd. All rights reserved.

Construction of a mathematical model of the human body, taking the nonlinear rigidity of the spine into account

NASA Technical Reports Server (NTRS)

Glukharev, K. K.; Morozova, N. I.; Potemkin, B. A.; Solovyev, V. S.; Frolov, K. V.

1973-01-01

A mathematical model of the human body was constructed, under the action of harmonic vibrations, in the 2.5-7 Hz frequency range. In this frequency range, the model of the human body as a vibrating system, with concentrated parameters is considered. Vertical movements of the seat and vertical components of vibrations of the human body are investigated.

Computational modeling of blast wave interaction with a human body and assessment of traumatic brain injury

NASA Astrophysics Data System (ADS)

Tan, X. G.; Przekwas, A. J.; Gupta, R. K.

2017-11-01

The modeling of human body biomechanics resulting from blast exposure poses great challenges because of the complex geometry and the substantial material heterogeneity. We developed a detailed human body finite element model representing both the geometry and the materials realistically. The model includes the detailed head (face, skull, brain and spinal cord), the neck, the skeleton, air cavities (lungs) and the tissues. Hence, it can be used to properly model the stress wave propagation in the human body subjected to blast loading. The blast loading on the human was generated from a simulated C4 explosion. We used the highly scalable solvers in the multi-physics code CoBi for both the blast simulation and the human body biomechanics. The meshes generated for these simulations are of good quality so that relatively large time-step sizes can be used without resorting to artificial time scaling treatments. The coupled gas dynamics and biomechanics solutions were validated against the shock tube test data. The human body models were used to conduct parametric simulations to find the biomechanical response and the brain injury mechanism due to blasts impacting the human body. Under the same blast loading condition, we showed the importance of inclusion of the whole body.

A functional-based segmentation of human body scans in arbitrary postures.

PubMed

Werghi, Naoufel; Xiao, Yijun; Siebert, Jan Paul

2006-02-01

This paper presents a general framework that aims to address the task of segmenting three-dimensional (3-D) scan data representing the human form into subsets which correspond to functional human body parts. Such a task is challenging due to the articulated and deformable nature of the human body. A salient feature of this framework is that it is able to cope with various body postures and is in addition robust to noise, holes, irregular sampling and rigid transformations. Although whole human body scanners are now capable of routinely capturing the shape of the whole body in machine readable format, they have not yet realized their potential to provide automatic extraction of key body measurements. Automated production of anthropometric databases is a prerequisite to satisfying the needs of certain industrial sectors (e.g., the clothing industry). This implies that in order to extract specific measurements of interest, whole body 3-D scan data must be segmented by machine into subsets corresponding to functional human body parts. However, previously reported attempts at automating the segmentation process suffer from various limitations, such as being restricted to a standard specific posture and being vulnerable to scan data artifacts. Our human body segmentation algorithm advances the state of the art to overcome the above limitations and we present experimental results obtained using both real and synthetic data that confirm the validity, effectiveness, and robustness of our approach.

Microwave non-contact imaging of subcutaneous human body tissues

PubMed Central

Chernokalov, Alexander; Khripkov, Alexander; Cho, Jaegeol; Druchinin, Sergey

2015-01-01

A small-size microwave sensor is developed for non-contact imaging of a human body structure in 2D, enabling fitness and health monitoring using mobile devices. A method for human body tissue structure imaging is developed and experimentally validated. Subcutaneous fat tissue reconstruction depth of up to 70 mm and maximum fat thickness measurement error below 2 mm are demonstrated by measurements with a human body phantom and human subjects. Electrically small antennas are developed for integration of the microwave sensor into a mobile device. Usability of the developed microwave sensor for fitness applications, healthcare, and body weight management is demonstrated. PMID:26609415

Relationship of insulin, glucose, leptin, IL-6 and TNF-α in human breast-milk with infant growth and body composition

PubMed Central

Fields, David A; Demerath, Ellen W.

2012-01-01

Numerous appetite, growth, obesity-related hormones and inflammatory factors are found in human breast-milk, but there is little evidence on their relationship with infant body composition. The purpose of the present cross-sectional pilot study was to assess the cross-sectional associations of appetite-regulating hormones and growth factors (leptin, insulin, glucose) and inflammatory factors (IL-6 and TNF-α) in human breast-milk with infant size, adiposity, and lean tissue at 1-month of age in healthy term infants. Human breast-milk was collected from nineteen exclusively breast-feeding mothers using one full breast expression between 8:00 and 10:00 am. The milk was then mixed, aliquoted, stored at −80°C and then centrifuged to remove the milk fat, prior to analyses using commercially available immunoassay kits; milk analytes were natural log transformed prior to analysis. Infant body composition was assessed using a Lunar iDXA v11-30.062 scanner (Infant whole body analysis enCore 2007 software, GE, Fairfield, CT). Maternal pre-pregnancy BMI was positively associated with milk leptin concentration (p=0.0027), and so maternal-BMI-adjusted Spearman correlations were examined between breast-milk analytes and infant growth and body composition variables. As previously reported, greater milk leptin was associated with lower BMIZ (r= −0.54, p=0.03). Glucose was positively associated with relateive weight (r = 0.6, p=0.01), and both fat and lean mass (0.43 – 0.44, p<0.10). Higher concentrations of milk insulin were associated with lower infant weight, relative weight, and lean mass (r = −0.49 – 0.58, p<0.06). Higher milk IL-6 was associated with lower relative weight, weight gain, percent fat, and fat mass (r = −0.55 – 0.70, p<0.03 for all), while higher TNF-α was associated with lower lean mass (r=−0.58, p=0.05), but not measures of adiposity. These preliminary data suggest for the first time that in the first months of life, breast-milk concentrations of insulin, glucose, IL-6 and TNF-α, in addition to leptin, may be bioactive and differentially influence the accrual of fat and lean body mass. PMID:22577092

Simulation study on transient electric shock characteristics of human body under high voltage ac transmission lines

NASA Astrophysics Data System (ADS)

Huang, Tao; Zou, Yanhui; Lv, Jianhong; Yang, Jinchun; Tao, Li; Zhou, Jianfei

2017-09-01

Human body under high-voltage AC transmission lines will produce a certain induced voltage due to the electrostatic induction. When the human body contacts with some grounded objects, the charges transfer from the body to the ground and produce contact current which may cause transient electric shock. Using CDEGS and ATP/EMTP, the paper proposes a method for quantitatively calculating the transient electric shock characteristics. It calculates the human body voltage, discharge current and discharge energy under certain 500kV compact-type transmission lines and predicts the corresponding human feelings. The results show that the average root value of discharge current is less than 10mA when the human body is under the 500kV compact-type transmission lines and the human body is overall safe if the transmission lines satisfy the relevant design specifications. It concludes that the electric field strength above the ground should be limited to 4kV/m through the residential area for the purpose of reducing the electromagnetic impact.

[The gift of human body's products: philosophical and ethical aspects].

PubMed

Baertschi, B

2014-09-01

In continental Europe, there is a very strong moral condemnation against putting parts or products of the human body on sale-and, consequently, against putting sperms and oocytes on sale. Only a gift is morally permissible. The situation is different in Anglo-Saxon countries. Who is right? Above all, it must be noticed that two views of the human body are facing each other here: for the first, the human body is a part of the person (so, it partakes of the person's dignity), whereas for the second, the human body is a possession of the person (the person is the owner of his/her body). In my opinion, the argument of dignity comes up against serious objections, and the property argument is more consistent. However, it does not follow that it would be judicious to put parts and products of the human body for sale on a market. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

Investigation of human body potential measured by a non-contact measuring system.

PubMed

Ichikawa, Norimitsu

2016-12-07

A human body is occasionally electrified in a room. This charged object will be a source of electrostatic accidents, including the malfunction of electronic equipment. Hence, prevention of these accidents is required. Accidents occasionally occur, even though antistatic clothes and shoes are used. One of the causes for these accidents is that there is a lack of the preventive measures. This situation occurs when using, for example, unconductive wax. In this study, human body potential (voltage) is measured using a non-contact measuring system. An investigation of the human body's voltage when using this system is conducted. The result demonstrates that the voltage of a human body wearing antistatic clothes and shoes or light clothes and slippers exceeds a malfunctioning voltage of a microelectronics device when the body walks on floors. Thus, accidents may occur even if a human body wearing the antistatic clothes walks on flooring. These results will be useful in estimating determination whether electrostatic accidents occur or not.

Automatic human body modeling for vision-based motion capture system using B-spline parameterization of the silhouette

NASA Astrophysics Data System (ADS)

Jaume-i-Capó, Antoni; Varona, Javier; González-Hidalgo, Manuel; Mas, Ramon; Perales, Francisco J.

2012-02-01

Human motion capture has a wide variety of applications, and in vision-based motion capture systems a major issue is the human body model and its initialization. We present a computer vision algorithm for building a human body model skeleton in an automatic way. The algorithm is based on the analysis of the human shape. We decompose the body into its main parts by computing the curvature of a B-spline parameterization of the human contour. This algorithm has been applied in a context where the user is standing in front of a camera stereo pair. The process is completed after the user assumes a predefined initial posture so as to identify the main joints and construct the human model. Using this model, the initialization problem of a vision-based markerless motion capture system of the human body is solved.

The Structure of Conscious Bodily Self-Perception during Full-Body Illusions

PubMed Central

Dobricki, Martin; de la Rosa, Stephan

2013-01-01

Previous research suggests that bodily self-identification, bodily self-localization, agency, and the sense of being present in space are critical aspects of conscious full-body self-perception. However, none of the existing studies have investigated the relationship of these aspects to each other, i.e., whether they can be identified to be distinguishable components of the structure of conscious full-body self-perception. Therefore, the objective of the present investigation is to elucidate the structure of conscious full-body self-perception. We performed two studies in which we stroked the back of healthy individuals for three minutes while they watched the back of a distant virtual body being synchronously stroked with a virtual stick. After visuo-tactile stimulation, participants assessed changes in their bodily self-perception with a custom made self-report questionnaire. In the first study, we investigated the structure of conscious full-body self-perception by analyzing the responses to the questionnaire by means of multidimensional scaling combined with cluster analysis. In the second study, we then extended the questionnaire and validated the stability of the structure of conscious full-body self-perception found in the first study within a larger sample of individuals by performing a principle components analysis of the questionnaire responses. The results of the two studies converge in suggesting that the structure of conscious full-body self-perception consists of the following three distinct components: bodily self-identification, space-related self-perception (spatial presence), and agency. PMID:24376765

The structure of conscious bodily self-perception during full-body illusions.

PubMed

Dobricki, Martin; de la Rosa, Stephan

2013-01-01

Previous research suggests that bodily self-identification, bodily self-localization, agency, and the sense of being present in space are critical aspects of conscious full-body self-perception. However, none of the existing studies have investigated the relationship of these aspects to each other, i.e., whether they can be identified to be distinguishable components of the structure of conscious full-body self-perception. Therefore, the objective of the present investigation is to elucidate the structure of conscious full-body self-perception. We performed two studies in which we stroked the back of healthy individuals for three minutes while they watched the back of a distant virtual body being synchronously stroked with a virtual stick. After visuo-tactile stimulation, participants assessed changes in their bodily self-perception with a custom made self-report questionnaire. In the first study, we investigated the structure of conscious full-body self-perception by analyzing the responses to the questionnaire by means of multidimensional scaling combined with cluster analysis. In the second study, we then extended the questionnaire and validated the stability of the structure of conscious full-body self-perception found in the first study within a larger sample of individuals by performing a principle components analysis of the questionnaire responses. The results of the two studies converge in suggesting that the structure of conscious full-body self-perception consists of the following three distinct components: bodily self-identification, space-related self-perception (spatial presence), and agency.

Pelvic dimorphism in relation to body size and body size dimorphism in humans.

PubMed

Kurki, Helen K

2011-12-01

Many mammalian species display sexual dimorphism in the pelvis, where females possess larger dimensions of the obstetric (pelvic) canal than males. This is contrary to the general pattern of body size dimorphism, where males are larger than females. Pelvic dimorphism is often attributed to selection relating to parturition, or as a developmental consequence of secondary sexual differentiation (different allometric growth trajectories of each sex). Among anthropoid primates, species with higher body size dimorphism have higher pelvic dimorphism (in converse directions), which is consistent with an explanation of differential growth trajectories for pelvic dimorphism. This study investigates whether the pattern holds intraspecifically in humans by asking: Do human populations with high body size dimorphism also display high pelvic dimorphism? Previous research demonstrated that in some small-bodied populations, relative pelvic canal size can be larger than in large-bodied populations, while others have suggested that larger-bodied human populations display greater body size dimorphism. Eleven human skeletal samples (total N: male = 229, female = 208) were utilized, representing a range of body sizes and geographical regions. Skeletal measurements of the pelvis and femur were collected and indices of sexual dimorphism for the pelvis and femur were calculated for each sample [ln(M/F)]. Linear regression was used to examine the relationships between indices of pelvic and femoral size dimorphism, and between pelvic dimorphism and female femoral size. Contrary to expectations, the results suggest that pelvic dimorphism in humans is generally not correlated with body size dimorphism or female body size. These results indicate that divergent patterns of dimorphism exist for the pelvis and body size in humans. Implications for the evaluation of the evolution of pelvic dimorphism and rotational childbirth in Homo are considered. Copyright © 2011 Elsevier Ltd. All rights reserved.

[Place and role of the body in Christianity].

PubMed

Verspieren, Patrick

Christianity has always been opposed to dualistic models devaluing the human body. The human person is created in God's image to be resurrected on the last day; his or her body is worthy of respect. It is in the body, or more precisely through it, that the human person is called to glorify and reveal the presence of God, manifested in the love between human beings. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

Utilising shade to optimize UV exposure for vitamin D

NASA Astrophysics Data System (ADS)

Turnbull, D. J.; Parisi, A. V.

2008-01-01

Numerous studies have stated that humans need to utilise full sun radiation, at certain times of the day, to assist the body in synthesising the required levels of vitamin D3. The time needed to be spent in the full sun depends on a number of factors, for example, age, skin type, latitude, solar zenith angle. Current Australian guidelines suggest exposure to approximately 1/6 to 1/3 of a minimum erythemal dose (MED), depending on age, would be appropriate to provide adequate vitamin D3 levels. The aim of the study was to determine the exposure times to diffuse solar UV to receive exposures of 1/6 and 1/3 MED for a changing solar zenith angle in order to assess the possible role that diffuse UV (scattered radiation) may play in vitamin D3 effective UV exposures (UVD3). Diffuse and global erythemal UV measurements were conducted at five minute intervals over a twelve month period for a solar zenith angle range of 4° to 80° at a latitude of 27.6° S. For diffuse UV exposures of 1/6 and 1/3 MED, solar zenith angles smaller than 60° and 50° respectively can be utilised for exposure times of less than 10 min. Spectral measurements showed that, for a solar zenith angle of 40°, the UVA (315-400 nm) in the diffuse component of the solar UV is reduced by approximately 62% compared to the UVA in the global UV, whereas UVD3 wavelengths are only reduced by approximately 43%. At certain latitudes, diffuse UV under shade may play an important role in providing the human body with adequate levels of UVD3 (290-330 nm) radiation without experiencing the high levels of damaging UVA observed in full sun.

Utilising shade to optimize UV exposure for vitamin D

NASA Astrophysics Data System (ADS)

Turnbull, D. J.; Parisi, A. V.

2008-06-01

Numerous studies have stated that humans need to utilise full sun radiation, at certain times of the day, to assist the body in synthesising the required levels of vitamin D3. The time needed to be spent in the full sun depends on a number of factors, for example, age, skin type, latitude, solar zenith angle. Current Australian guidelines suggest exposure to approximately 1/6 to 1/3 of a minimum erythemal dose (MED), depending on age, would be appropriate to provide adequate vitamin D3 levels. The aim of the study was to determine the exposure times to diffuse solar UV to receive exposures of 1/6 and 1/3 MED for a changing solar zenith angle in order to assess the possible role that diffuse UV (scattered radiation) may play in vitamin D3 effective UV exposures (UVD3). Diffuse and global erythemal UV measurements were conducted at five minute intervals over a twelve month period for a solar zenith angle range of 4° to 80° at a latitude of 27.6° S. For a diffuse UV exposure of 1/3 MED, solar zenith angles smaller than approximately 50° can be utilised for exposure times of less than 10 min. Spectral measurements showed that, for a solar zenith angle of 40°, the UVA (315-400 nm) in the diffuse component of the solar UV is reduced by approximately 62% compared to the UVA in the global UV, whereas UVD3 wavelengths are only reduced by approximately 43%. At certain latitudes, diffuse UV under shade may play an important role in providing the human body with adequate levels of UVD3 (290-315 nm) radiation without experiencing the high levels of UVA observed in full sun.

Body size, body proportions, and encephalization in a Middle Pleistocene archaic human from northern China.

PubMed

Rosenberg, Karen R; Zuné, Lü; Ruff, Christopher B

2006-03-07

The unusual discovery of associated cranial and postcranial elements from a single Middle Pleistocene fossil human allows us to calculate body proportions and relative cranial capacity (encephalization quotient) for that individual rather than rely on estimates based on sample means from unassociated specimens. The individual analyzed here (Jinniushan) from northeastern China at 260,000 years ago is the largest female specimen yet known in the human fossil record and has body proportions (body height relative to body breadth and relative limb length) typical of cold-adapted populations elsewhere in the world. Her encephalization quotient of 4.15 is similar to estimates for late Middle Pleistocene humans that are based on mean body size and mean brain size from unassociated specimens.

Posturographic destabilization in eating disorders in female patients exposed to body image related phobic stimuli.

PubMed

Forghieri, M; Monzani, D; Mackinnon, A; Ferrari, S; Gherpelli, C; Galeazzi, G M

2016-08-26

Human postural control is dependent on the central integration of vestibular, visual and proprioceptive inputs. Psychological states can affect balance control: anxiety, in particular, has been shown to influence balance mediated by visual stimuli. We hypothesized that patients with eating disorders would show postural destabilization when exposed to their image in a mirror and to the image of a fashion model representing their body ideal in comparison to body neutral stimuli. Seventeen females patients attending a day centre for the treatment of eating disorders were administered psychometric measures of body dissatisfaction, anxiety, depression and underwent posturographic measures with their eyes closed, open, watching a neutral stimulus, while exposed to a full length mirror and to an image of a fashion model corresponding to their body image. Results were compared to those obtained by eighteen healthy subjects. Eating disordered patients showed higher levels of body dissatisfaction and higher postural destabilization than controls, but this was limited to the conditions in which they were exposed to their mirror image or a fashion model image. Postural destabilization under these conditions correlated with measures of body dissatisfaction. In eating disordered patients, body related stimuli seem to act as phobic stimuli in the posturographic paradigm used. If confirmed, this has the potential to be developed for diagnostic and therapeutic purposes. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

HUMAN BODY SHAPE INDEX BASED ON AN EXPERIMENTALLY DERIVED MODEL OF HUMAN GROWTH

PubMed Central

Lebiedowska, Maria K.; Alter, Katharine E.; Stanhope, Steven J.

2009-01-01

Objectives To test the assumption of geometrically similar growth by developing experimentally derived models of human body growth during the age interval of 5–18 years; to use the derived growth models to establish a new Human Body Shape Index (HBSI) based on natural age related changes in HBS; and to compare various metrics of relative body weight (body mass index, ponderal index, HBSI) in a sample of 5–18 year old children. Study design Non-disabled Polish children (N=847) participated in this descriptive study. To model growth, the best fit between body height (H) and body mass (M) was calculated for each sex with the allometric equation M= miHχ. HBSI and HBSI were calculated separately for girls and boys, using sex-specific values for χ and a general HBSI from combined data. The customary body mass and ponderal indices were calculated and compared to HBSI values. Results The models of growth were M=13.11H2.84 (R2=.90) and M=13.64H2.68 (R2=.91) for girls and boys respectively. HBSI values contained less inherent variability and were influenced least by growth (age and height) than customary indices. Conclusion Age-related growth during childhood is sex-specific and not geometrically similar. Therefore, indices of human body shape formulated from experimentally derived models of human growth are superior to customary geometric similarity-based indices for the characterization of human body shape in children during the formative growth years. PMID:18154897

Embodying animals: Body-part compatibility in mammalian, reptile and aves classes.

PubMed

Pacione, Sandra M; Welsh, Timothy N

2015-09-01

The purpose of the present study was to determine how humans code homologous body parts of nonhuman mammal, reptilian, and aves animals with respect to the representation of the human body. To this end, participants completed body-part compatibility tasks in which responses were executed to colored targets that were superimposed over the upper limbs, lower limbs or head of different animals in different postures. In Experiment 1, the images were of meekats and lizards in bipedal and quadrupedal postures. In Experiment 2, the images were of a human, a penguin, and an owl in a bipedal posture with upper limbs stretched out. Overall, the results revealed that the limbs of nonhuman mammals (meerkat and human) were consistently mapped onto the homologous human body parts only when the mammals were in a bipedal posture. Specifically, body-part compatibility effects emerged for the human and the meerkat in a bipedal posture, but not the meerkat in the quadrupedal posture. Further, consistent body-part compatibility effects were not observed for the lizard in the quadrupedal posture or for the lizard, penguin, or owl in a bipedal posture. The pattern of results suggests that the human bipedal body representation may distinguish taxonomical classes and is most highly engaged when viewing homologous body parts of mammalian animals. Copyright © 2015 Elsevier B.V. All rights reserved.

Field-Based Optimal Placement of Antennas for Body-Worn Wireless Sensors

PubMed Central

Januszkiewicz, Łukasz; Di Barba, Paolo; Hausman, Sławomir

2016-01-01

We investigate a case of automated energy-budget-aware optimization of the physical position of nodes (sensors) in a Wireless Body Area Network (WBAN). This problem has not been presented in the literature yet, as opposed to antenna and routing optimization, which are relatively well-addressed. In our research, which was inspired by a safety-critical application for firefighters, the sensor network consists of three nodes located on the human body. The nodes communicate over a radio link operating in the 2.4 GHz or 5.8 GHz ISM frequency band. Two sensors have a fixed location: one on the head (earlobe pulse oximetry) and one on the arm (with accelerometers, temperature and humidity sensors, and a GPS receiver), while the position of the third sensor can be adjusted within a predefined region on the wearer’s chest. The path loss between each node pair strongly depends on the location of the nodes and is difficult to predict without performing a full-wave electromagnetic simulation. Our optimization scheme employs evolutionary computing. The novelty of our approach lies not only in the formulation of the problem but also in linking a fully automated optimization procedure with an electromagnetic simulator and a simplified human body model. This combination turns out to be a computationally effective solution, which, depending on the initial placement, has a potential to improve performance of our example sensor network setup by up to about 20 dB with respect to the path loss between selected nodes. PMID:27196911

Fall Protection Characteristics of Safety Belts and Human Impact Tolerance.

PubMed

Hino, Yasumichi; Ohdo, Katsutoshi; Takahashi, Hiroki

2014-08-23

Many fatal accidents due to falls from heights have occurred at construction sites not only in Japan but also in other countries. This study aims to determine the fall prevention performance of two types of safety belts: a body belt 1) , which has been used for more than 40 yr in the Japanese construction industry as a general type of safety equipment for fall accident prevention, and a full harness 2, 3) , which has been used in many other countries. To determine human tolerance for impact trauma, this study discusses features of safety belts with reference 4-9) to relevant studies in the medical science, automobile crash safety, and aircrew safety. For this purpose, simple drop tests were carried out in a virtual workplace to measure impact load, head acceleration, and posture in the experiments, the Hybrid-III pedestrian model 10) was used as a human dummy. Hybrid-III is typically employed in official automobile crash tests (New Car Assessment Program: NCAP) and is currently recognized as a model that faithfully reproduces dynamic responses. Experimental results shows that safety performance strongly depends on both the variety of safety belts used and the shock absorbers attached onto lanyards. These findings indicate that fall prevention equipment, such as safety belts, lanyards, and shock absorbers, must be improved to reduce impact injuries to the human head and body during falls.

Fall protection characteristics of safety belts and human impact tolerance.

PubMed

Hino, Yasumichi; Ohdo, Katsutoshi; Takahashi, Hiroki

2014-01-01

Many fatal accidents due to falls from heights have occurred at construction sites not only in Japan but also in other countries. This study aims to determine the fall prevention performance of two types of safety belts: a body belt, which has been used for more than 40 yr in the Japanese construction industry as a general type of safety equipment for fall accident prevention, and a full harness, which has been used in many other countries. To determine human tolerance for impact trauma, this study discusses features of safety belts with reference to relevant studies in the medical science, automobile crash safety, and aircrew safety. For this purpose, simple drop tests were carried out in a virtual workplace to measure impact load, head acceleration, and posture in the experiments, the Hybrid-III pedestrian model was used as a human dummy. Hybrid-III is typically employed in official automobile crash tests (New Car Assessment Program: NCAP) and is currently recognized as a model that faithfully reproduces dynamic responses. Experimental results shows that safety performance strongly depends on both the variety of safety belts used and the shock absorbers attached onto lanyards. These findings indicate that fall prevention equipment, such as safety belts, lanyards, and shock absorbers, must be improved to reduce impact injuries to the human head and body during falls.

Fall Protection Characteristics of Safety Belts and Human Impact Tolerance

PubMed Central

HINO, Yasumichi; OHDO, Katsutoshi; TAKAHASHI, Hiroki

2014-01-01

Abstract: Many fatal accidents due to falls from heights have occurred at construction sites not only in Japan but also in other countries. This study aims to determine the fall prevention performance of two types of safety belts: a body belt1), which has been used for more than 40 yr in the Japanese construction industry as a general type of safety equipment for fall accident prevention, and a full harness2, 3), which has been used in many other countries. To determine human tolerance for impact trauma, this study discusses features of safety belts with reference4,5,6,7,8,9) to relevant studies in the medical science, automobile crash safety, and aircrew safety. For this purpose, simple drop tests were carried out in a virtual workplace to measure impact load, head acceleration, and posture in the experiments, the Hybrid-III pedestrian model10) was used as a human dummy. Hybrid-III is typically employed in official automobile crash tests (New Car Assessment Program: NCAP) and is currently recognized as a model that faithfully reproduces dynamic responses. Experimental results shows that safety performance strongly depends on both the variety of safety belts used and the shock absorbers attached onto lanyards. These findings indicate that fall prevention equipment, such as safety belts, lanyards, and shock absorbers, must be improved to reduce impact injuries to the human head and body during falls. PMID:25345426

[Measurement of human body fat by means of gravimetry. Application of Archimedes' principle].

PubMed

Dettwiler, W; Ribordy, M; Donath, A; Scherrer, J R

1978-12-02

The weighing of the human body under water is an application of Archimedes' law. Fat being lighter than water or than the structures of lean body mass, body fat can be measured by determining the specific gravity of the human body; that is, by underwater weighing. Body fat has been determined in an "ideal" sample of 14 men and 23 women, all aged 20 years. Testing against a reference measure of body fat makes it possible to test the validity of some anthropometric measurements and of some indices of obesity. These indices offer no advantages over anthropometric measurements.

Nodular melanoma serendipitously detected by airport full body scanners.

PubMed

Mayer, Jonathan E; Adams, Brian B

2015-01-01

Nodular melanoma is the most dangerous form of melanoma and often evades early detection. We present a frequently traveling businessman whose nodular melanoma was detected by airport full body scanners. For about 20 flights over 2 months, the airport full body scanners singled out an area on his left lower leg for a pat-down. Dermatologic examination discovered a nodular melanoma in this area, and after surgical excision, the man traveled without incident. This case raises the possibility of using full body imaging in the detection of melanomas, especially of the nodular subtype. In its current form, full body scanning would most likely not be sensitive or specific enough to become a recommended screening tool. Nonetheless, for travelers with areas repeatedly singled out by the machines without a known justification, airport scanners could serve as incidental free screening for suspicious nodular lesions that should prompt dermatologist referral. © 2014 S. Karger AG, Basel.

Brazilian legal and bioethical approach about donation for research and patents of human body parts.

PubMed

Fernandes, Márcia Santana; Silla, Lúcia; Goldim, José Roberto; Martins-Costa, Judith

2017-07-01

The aim of this paper is to explain why the Brazilian legal system does not accept commercialization or commodification of human body parts, including genes or cells. As a consequence, in Brazil, the donation of human body parts for research-including basic or translational-must be made altruistically. For the same reason, the Brazilian patent system cannot be applied to human parts, cells or genes. Here, we present a qualitative analysis of juridical, bioethical, and social reasoning related to the legal status of human body parts especially in biobanks, as well as a description of the Brazilian legal system for clarification. Our aim is to discuss the responsibility of researchers for making available the scientific information resulting from scientific research and biobank storage of human body parts and to ensure the free utilization of knowledge in human health research.

Energy absorption capability of foam-based composite materials and their applications as seat cushions in aircraft crashworthiness

NASA Astrophysics Data System (ADS)

Kh. Beheshti, Hamid

This study is focusing on the application of foam materials in aviation. These materials are being used for acoustic purposes, as padding in the finished interior panels of the aircraft, and as seat cushions. Foams are mostly used in seating applications. Since seat cushion is directly interacting with the body of occupant, it has to be ergonomically comfortable beside of absorbing the energy during the impact. All the seats and seat cushions have to pass regulations defined by Federal Aviation Administration (FAA). In fact, all airplane companies are required to certify the subcomponents of aircrafts before installing them on the main structure, fuselage. Current Federal Aviation Administration Regulations require a dynamic sled test of the entire seat system for certifying the seat cushions. This dynamic testing is required also for replacing the deteriorated cushions with new cushions. This involves a costly and time-consuming certification process. AGATE group has suggested a procedure based on quasi-static testing in order to certify new seat cushions without conducting full-scale dynamic sled testing. AGATE subcomponent methodology involves static tests of the energy-absorbing foam cushions and design validation by conducting a full-scale dynamic seat test. Microscopic and macroscopic studies are necessary to provide a complete understanding about performance of foams during the crash. Much investigation has been done by different sources to obtain the reliable modeling in terms of demonstration of mechanical behavior of foams. However, rate sensitivity of foams needs more attention. A mathematical hybrid dynamic model for the cushion underneath of the human body will be taken into consideration in this research. Analytical and finite element codes such as MADYMO and LS-DYNA codes have the potential to greatly speed up the crashworthy design process, to help certify seats and aircraft to dynamic crash loads, to predict seat and occupant response to impact with the probability of injury, and to evaluate numerous crash scenarios not economically feasible with full-scale crash testing. Therefore, these codes are being used to find the accurate response of spinal load during the impact of model including human body, seat cushion and seat under different acceleration pulses. (Abstract shortened by UMI.)

Disposition pathways and pharmacokinetics of herbal medicines in humans.

PubMed

He, S-M; Li, C G; Liu, J-P; Chan, E; Duan, W; Zhou, S-F

2010-01-01

Pharmacokinetic studies have become an integral part of modern drug development, but these studies are not regulatory needs for herbal remedies. This paper updates our current knowledge on the disposition pathways and pharmacokinetic properties of commonly used herbal medicines in humans. To retrieve relevant data, the authors have searched through computer-based literatures by full text search in Medline (via Pubmed), ScienceDirect, Current Contents Connect (ISI), Cochrance Library, CINAHL (EBSCO), CrossRef Search and Embase (all from inception to May 2010). Many herbal compounds undergo Phase I and/or Phase II metabolism in vivo, with cytochrome P450s (CYPs) and uridine diphosphate glucuronosyltransferases (UGTs) playing a major role. Some herbal ingredients are substrates of P-glycoprotein (P-gp) which is highly expressed in the intestine, liver, brain and kidney. As such, the activities of these drug metabolizing enzymes and drug transporters are determining factors for the in vivo bioavailability, disposition and distribution of herbal remedies. There are increasing pharmacokinetic studies of herbal remedies, but these studies are mainly focused on a small number of herbal remedies including St John's wort, milk thistle, sculcap, curcumin, echinacea, ginseng, ginkgo, and ginger. The pharmacokinetic data of a small number of purified herbal ingredients, including anthocyanins, berberine, catechins, curcumin, lutein and quercetin, are available. For the majority of herbal remedies used in folk medicines, data on their disposition and biological fate in humans are lacking or in paucity. For a herbal medicine, the pharmacological effect is achieved when the bioactive agents or the metabolites reach and sustain proper levels at their sites of action. Both the dose levels and fates of active components in the body govern their target-site concentrations after administration of an herbal remedy. In this regard, a safe and optimal use of herbal medicines requires a full understanding of their pharmacokinetic profiles. To optimize the use of herbal remedies, further clinical studies to explore their biological fate including the disposition pathways and kinetics in the human body are certainly needed.

Cold-Water Immersion for Hyperthermic Humans Wearing American Football Uniforms

PubMed Central

Miller, Kevin C.; Swartz, Erik E.; Long, Blaine C.

2015-01-01

Context Current treatment recommendations for American football players with exertional heatstroke are to remove clothing and equipment and immerse the body in cold water. It is unknown if wearing a full American football uniform during cold-water immersion (CWI) impairs rectal temperature (Trec) cooling or exacerbates hypothermic afterdrop. Objective To determine the time to cool Trec from 39.5°C to 38.0°C while participants wore a full American football uniform or control uniform during CWI and to determine the uniform's effect on Trec recovery postimmersion. Design Crossover study. Setting Laboratory. Patients or Other Participants A total of 18 hydrated, physically active, unacclimated men (age = 22 ± 3 years, height = 178.8 ± 6.8 cm, mass = 82.3 ± 12.6 kg, body fat = 13% ± 4%, body surface area = 2.0 ± 0.2 m2). Intervention(s) Participants wore the control uniform (undergarments, shorts, crew socks, tennis shoes) or full uniform (control plus T-shirt; tennis shoes; jersey; game pants; padding over knees, thighs, and tailbone; helmet; and shoulder pads). They exercised (temperature approximately 40°C, relative humidity approximately 35%) until Trec reached 39.5°C. They removed their T-shirts and shoes and were then immersed in water (approximately 10°C) while wearing each uniform configuration; time to cool Trec to 38.0°C (in minutes) was recorded. We measured Trec (°C) every 5 minutes for 30 minutes after immersion. Main Outcome Measure(s) Time to cool from 39.5°C to 38.0°C and Trec. Results The Trec cooled to 38.0°C in 6.19 ± 2.02 minutes in full uniform and 8.49 ± 4.78 minutes in control uniform (t17 = −2.1, P = .03; effect size = 0.48) corresponding to cooling rates of 0.28°C·min−1 ± 0.12°C·min−1 in full uniform and 0.23°C·min−1 ± 0.11°C·min−1 in control uniform (t17 = 1.6, P = .07, effect size = 0.44). The Trec postimmersion recovery did not differ between conditions over time (F1,17 = 0.6, P = .59). Conclusions We speculate that higher skin temperatures before CWI, less shivering, and greater conductive cooling explained the faster cooling in full uniform. Cooling rates were considered ideal when the full uniform was worn during CWI, and wearing the full uniform did not cause a greater postimmersion hypothermic afterdrop. Clinicians may immerse football athletes with hyperthermia wearing a full uniform without concern for negatively affecting body-core cooling. PMID:26090706

The ownership of human body: an islamic perspective.

PubMed

Aramesh, Kiarash

2009-01-01

Using human dead body for medical purposes is a common practice in medical schools and hospitals throughout the world. Iran, as an Islamic country is not an exception. According to the Islamic view, the body, like the soul, is a "gift" from God; therefore, human being does not possess absolute ownership on his or her body. But, the ownership of human beings on their bodies can be described as a kind of "stewardship". Accordingly, any kind of dissection or mutilation of the corpse is forbidden, even with the informed consent of the dead or his/her relatives. The exception of this principle is when such procedures are necessary for saving lives of other persons. In this article using the human dead body for medical education, research and treatment is discussed and the perspective of Iranian Shiite religious scholars in this regard is explained.

Recombinant human Tat-Hsp70-2: A tool for neuroprotection.

PubMed

Cappelletti, Pamela; Binda, Elisa; Tunesi, Marta; Albani, Diego; Giordano, Carmen; Molla, Gianluca; Pollegioni, Loredano

2017-10-01

Human Hsp70-2 is a chaperone expressed mainly in the nervous system. Up to now, no study has reported on the recombinant expression of this important human chaperone. Herein, we describe the successful purification and characterization of recombinant human Hsp70-2 in Escherichia coli in both the full-length and the chimeric protein containing the protein transduction domain corresponding to the trans-activator of transcription (Tat) from HIV. Under optimized conditions, the Tat-Hsp70-2 was expressed in a soluble form and purified by two chromatographic steps (in a 3.6 mg/L fermentation broth yield): recombinant Tat-Hsp70-2 was folded and showed ATPase activity. In contrast, the full-length recombinant protein was only expressed in the form of inclusion bodies and thus was purified following a refolding procedure. The refolded Hsp70-2 protein was inactive and the protein conformation slightly altered as compared to the corresponding Tat-fused variant. The Tat-Hsp70-2 protein (100 nM), when added to human neuroblastoma SH-SY5Y cells subjected to hydrogen peroxide or 6-hydroxydopamine stress, partially protected from the deleterious effect of these treatments. This work describes an approach for the functional expression of human Tat-Hsp70-2 that provides sufficient material for detailed structure-function studies and for testing its ability to protect neuroblastoma cells from oxidative stress. Copyright © 2016 Elsevier Inc. All rights reserved.

78 FR 54731 - Update to the List of Basic Medical Supplies

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-05

... Suture removal kits Syringes Thermometers, mercury for measuring human body temperature Tongue depressors... equipment Orthopedic traction devices and tables Human body positioners including pads, wedges, cradles... staples; and removal kits Tourniquets Thermometers for measuring human body temperature Clinical basins...

36 CFR 1002.14 - Sanitation and refuse.

Code of Federal Regulations, 2010 CFR

2010-07-01

... areas, the disposal of human body waste, except at designated locations or in fixtures provided for that purpose. (9) In nondeveloped areas, the disposal of human body waste within 100 feet of a water source... human body waste. Violation of these conditions is prohibited. ...

36 CFR 1002.14 - Sanitation and refuse.

Code of Federal Regulations, 2011 CFR

2011-07-01

... areas, the disposal of human body waste, except at designated locations or in fixtures provided for that purpose. (9) In nondeveloped areas, the disposal of human body waste within 100 feet of a water source... human body waste. Violation of these conditions is prohibited. ...

Human body perception and higher-level person perception are dissociated in early development.

PubMed

Slaughter, Virginia

2011-01-01

Abstract Developmental data support the proposal that human body perceptual processing is distinct from other aspects of person perception. Infants are sensitive to human bodily motion and attribute goals to human arm movements before they demonstrate recognition of human body structure. The developmental data suggest the possibility of bidirectional linkages between EBA- and FBA-mediated representations and these higher-level elements of person perception.

Optimal frequency range for medical radar measurements of human heartbeats using body-contact radar.

PubMed

Brovoll, Sverre; Aardal, Øyvind; Paichard, Yoann; Berger, Tor; Lande, Tor Sverre; Hamran, Svein-Erik

2013-01-01

In this paper the optimal frequency range for heartbeat measurements using body-contact radar is experimentally evaluated. A Body-contact radar senses electromagnetic waves that have penetrated the human body, but the range of frequencies that can be used are limited by the electric properties of the human tissue. The optimal frequency range is an important property needed for the design of body-contact radar systems for heartbeat measurements. In this study heartbeats are measured using three different antennas at discrete frequencies from 0.1 - 10 GHz, and the strength of the received heartbeat signal is calculated. To characterize the antennas, when in contact with the body, two port S-parameters(†) are measured for the antennas using a pork rib as a phantom for the human body. The results shows that frequencies up to 2.5 GHz can be used for heartbeat measurements with body-contact radar.

In vivo self-gated 23 Na MRI at 7 T using an oval-shaped body resonator.

PubMed

Platt, Tanja; Umathum, Reiner; Fiedler, Thomas M; Nagel, Armin M; Bitz, Andreas K; Maier, Florian; Bachert, Peter; Ladd, Mark E; Wielpütz, Mark O; Kauczor, Hans-Ulrich; Behl, Nicolas G R

2018-02-09

This work faces three challenges of sodium ( 23 Na) torso MRI on the way to quantitative 23 Na MRI: Development of a 23 Na radiofrequency transmit and receive coil covering a large part of the human body in width and length for 23 Na MRI at 7 T; reduction of blurring due to respiration in free-breathing 23 Na MRI using a self-gating approach; and reduction of image noise using a compressed-sensing reconstruction. An oval-shaped birdcage resonator with a large field of view of (400 mm) 3 and a homogeneous transmit and receive field distribution was designed, simulated, and implemented on a 7T MR system. In free-breathing 3-dimensional radial 23 Na MRI (acquisition time ≈ 30 minutes), retrospective respiratory self-gating was applied, which sorts the acquired projections into two respiratory states based on the intrinsic respiration-dependent signal changes. Furthermore, a 3-dimensional dictionary-learning compressed-sensing reconstruction was applied. The developed body coil provided homogeneous radiofrequency excitation (flip angle error of 4.9% in central region of interest of 23 × 13 × 10 cm 3 ) and homogeneous signal reception. The self-gating approach allowed for separation of the full data set into two subsets associated with different respiratory states (inhaled and exhaled), and thereby reduced blurring due to respiration in the separated images. Image noise was markedly reduced by the compressed-sensing algorithm. The presented body coil enables full body width 23 Na MRI with long z-axis coverage at 7 T for the first time. Additionally, the retrospective respiratory self-gating performance is demonstrated for free-breathing lung and abdominal 23 Na MRI in 3 subjects. © 2018 International Society for Magnetic Resonance in Medicine.

A Circuit Model of Real Time Human Body Hydration.

PubMed

Asogwa, Clement Ogugua; Teshome, Assefa K; Collins, Stephen F; Lai, Daniel T H

2016-06-01

Changes in human body hydration leading to excess fluid losses or overload affects the body fluid's ability to provide the necessary support for healthy living. We propose a time-dependent circuit model of real-time human body hydration, which models the human body tissue as a signal transmission medium. The circuit model predicts the attenuation of a propagating electrical signal. Hydration rates are modeled by a time constant τ, which characterizes the individual specific metabolic function of the body part measured. We define a surrogate human body anthropometric parameter θ by the muscle-fat ratio and comparing it with the body mass index (BMI), we find theoretically, the rate of hydration varying from 1.73 dB/min, for high θ and low τ to 0.05 dB/min for low θ and high τ. We compare these theoretical values with empirical measurements and show that real-time changes in human body hydration can be observed by measuring signal attenuation. We took empirical measurements using a vector network analyzer and obtained different hydration rates for various BMI, ranging from 0.6 dB/min for 22.7 [Formula: see text] down to 0.04 dB/min for 41.2 [Formula: see text]. We conclude that the galvanic coupling circuit model can predict changes in the volume of the body fluid, which are essential in diagnosing and monitoring treatment of body fluid disorder. Individuals with high BMI would have higher time-dependent biological characteristic, lower metabolic rate, and lower rate of hydration.

Lumbar joint torque estimation based on simplified motion measurement using multiple inertial sensors.

PubMed

Miyajima, Saori; Tanaka, Takayuki; Imamura, Yumeko; Kusaka, Takashi

2015-01-01

We estimate lumbar torque based on motion measurement using only three inertial sensors. First, human motion is measured by a 6-axis motion tracking device that combines a 3-axis accelerometer and a 3-axis gyroscope placed on the shank, thigh, and back. Next, the lumbar joint torque during the motion is estimated by kinematic musculoskeletal simulation. The conventional method for estimating joint torque uses full body motion data measured by an optical motion capture system. However, in this research, joint torque is estimated by using only three link angles of the body, thigh, and shank. The utility of our method was verified by experiments. We measured motion of bendung knee and waist simultaneously. As the result, we were able to estimate the lumbar joint torque from measured motion.

Multilayer limb quasi-static electromagnetic modeling with experiments for Galvanic coupling type IBC.

PubMed

Pun, S H; Gao, Y M; Mou, P A; Mak, P U; Vai, M I; Du, M

2010-01-01

Intra-body communication (IBC) is a new, emerging, short-range and human body based communication methodology. It is a technique to network various devices on human body, by utilizing the conducting properties of human tissues. For currently fast developed Body area network(BAN)/Body sensor network(BSN), IBC is believed to have advantages in power consumption, electromagnetic radiation, interference from external electromagnetic noise, security, and restriction in spectrum resource. In this article, the authors propose an improved mathematical model, which includes both electrical properties and proportion of human tissues, for IBC on a human limb. By solving the mathematical model analytically on four-layer system (skin, fat, muscle, and bone) and conducting in-vivo experiment, a comparison has been conducted.

Estimation of skeletal movement of human locomotion from body surface shapes using dynamic spatial video camera (DSVC) and 4D human model.

PubMed

Saito, Toshikuni; Suzuki, Naoki; Hattori, Asaki; Suzuki, Shigeyuki; Hayashibe, Mitsuhiro; Otake, Yoshito

2006-01-01

We have been developing a DSVC (Dynamic Spatial Video Camera) system to measure and observe human locomotion quantitatively and freely. A 4D (four-dimensional) human model with detailed skeletal structure, joint, muscle, and motor functionality has been built. The purpose of our research was to estimate skeletal movements from body surface shapes using DSVC and the 4D human model. For this purpose, we constructed a body surface model of a subject and resized the standard 4D human model to match with geometrical features of the subject's body surface model. Software that integrates the DSVC system and the 4D human model, and allows dynamic skeletal state analysis from body surface movement data was also developed. We practically applied the developed system in dynamic skeletal state analysis of a lower limb in motion and were able to visualize the motion using geometrically resized standard 4D human model.

Relationship among serum taurine, serum adipokines, and body composition during 8-week human body weight control program.

PubMed

You, Jeong Soon; Park, Ji Yeon; Zhao, Xu; Jeong, Jin Seok; Choi, Mi Ja; Chang, Kyung Ja

2013-01-01

Human adipose tissue is not only a storage organ but also an active endocrine organ to release adipokines. This study was conducted to investigate the relationship among serum taurine and adipokine levels, and body composition during 8-week human body weight control program in obese female college students. The program consisted of diet therapy, exercise, and behavior modification. After the program, body weight, body fat mass, percent body fat, and body mass index (BMI) were significantly decreased. Serum triglyceride (TG), total cholesterol (TC), and low-density lipoprotein cholesterol (LDL-C) levels were significantly decreased. Also serum adiponectin level was significantly increased and serum leptin level was significantly decreased. There were no differences in serum taurine and homocysteine levels. The change of serum adiponectin level was positively correlated with change of body fat mass and percent body fat. These results may suggest that body fat loss by human body weight control program is associated with an increase in serum adiponectin in obese female college students. Therefore, further study such as taurine intervention study is needed to know more exact correlation between dietary taurine intake and serum adipokines or body composition.

Differences between perception of human faces and body shapes: evidence from the composite illusion.

PubMed

Soria Bauser, Denise A; Suchan, Boris; Daum, Irene

2011-01-01

The present study aimed to investigate whether human body forms--like human faces--undergo holistic processing. Evidence for holistic face processing comes from the face composite effect: two identical top halves of a face are perceived as being different if they are presented with different bottom parts. This effect disappears if both bottom halves are shifted laterally (misaligned) or if the stimulus is rotated by 180°. We investigated whether comparable composite effects are observed for human faces and human body forms. Matching of upright faces was more accurate and faster for misaligned compared to aligned presentations. By contrast, there were no processing differences between aligned and misaligned bodies. An inversion effect emerged, with better recognition performance for upright compared to inverted bodies but not faces. The present findings provide evidence for the assumption that holistic processing--investigated with the composite illusion--is not involved in the perception of human body forms. Copyright © 2010 Elsevier Ltd. All rights reserved.

Investigation of human body potential measured by a non-contact measuring system

PubMed Central

ICHIKAWA, Norimitsu

2016-01-01

A human body is occasionally electrified in a room. This charged object will be a source of electrostatic accidents, including the malfunction of electronic equipment. Hence, prevention of these accidents is required. Accidents occasionally occur, even though antistatic clothes and shoes are used. One of the causes for these accidents is that there is a lack of the preventive measures. This situation occurs when using, for example, unconductive wax. In this study, human body potential (voltage) is measured using a non-contact measuring system. An investigation of the human body’s voltage when using this system is conducted. The result demonstrates that the voltage of a human body wearing antistatic clothes and shoes or light clothes and slippers exceeds a malfunctioning voltage of a microelectronics device when the body walks on floors. Thus, accidents may occur even if a human body wearing the antistatic clothes walks on flooring. These results will be useful in estimating determination whether electrostatic accidents occur or not. PMID:27319403

Evaluation of kinematics and injuries to restrained occupants in far-side crashes using full-scale vehicle and human body models.

PubMed

Arun, Mike W J; Umale, Sagar; Humm, John R; Yoganandan, Narayan; Hadagali, Prasanaah; Pintar, Frank A

2016-09-01

The objective of the current study was to perform a parametric study with different impact objects, impact locations, and impact speeds by analyzing occupant kinematics and injury estimations using a whole-vehicle and whole-body finite element-human body model (FE-HBM). To confirm the HBM responses, the biofidelity of the model was validated using data from postmortem human surrogate (PMHS) sled tests. The biofidelity of the model was validated using data from sled experiments and correlational analysis (CORA). Full-scale simulations were performed using a restrained Global Human Body Model Consortium (GHBMC) model seated on a 2001 Ford Taurus model using a far-side lateral impact condition. The driver seat was placed in the center position to represent a nominal initial impact condition. A 3-point seat belt with pretensioner and retractor was used to restrain the GHBMC model. A parametric study was performed using 12 simulations by varying impact locations, impacting object, and impact speed using the full-scale models. In all 12 simulations, the principal direction of force (PDOF) was selected as 90°. The impacting objects were a 10-in.-diameter rigid vertical pole and a movable deformable barrier. The impact location of the pole was at the C-pillar in the first case, at the B-pillar in the second case, and, finally, at the A-pillar in the third case. The vehicle and the GHBMC models were defined an initial velocity of 35 km/h (high speed) and 15 km/h (low speed). Excursion of the head center of gravity (CG), T6, and pelvis were measured from the simulations. In addition, injury risk estimations were performed on head, rib cage, lungs, kidneys, liver, spleen, and pelvis. The average CORA rating was 0.7. The shoulder belt slipped in B- and C-pillar impacts but somewhat engaged in the A-pillar case. In the B-pillar case, the head contacted the intruding struck-side structures, indicating higher risk of injury. Occupant kinematics depended on interaction with restraints and internal structures-especially the passenger seat. Risk analysis indicated that the head had the highest risk of sustaining an injury in the B-pillar case compared to the other 2 cases. Higher lap belt load (3.4 kN) may correspond to the Abbreviated Injury Scale (AIS) 2 pelvic injury observed in the B-pillar case. Risk of injury to other soft anatomical structures varied with impact configuration and restraint interaction. The average CORA rating was 0.7. In general, the results indicated that the high-speed impacts against the pole resulted in severe injuries, higher excursions followed by low-speed pole, high-speed moving deformable barrier (MDB), and low-speed MDB impacts. The vehicle and occupant kinematics varied with different impact setups and the latter kinematics were likely influenced by restraint effectiveness. Increased restraint engagement increased the injury risk to the corresponding anatomic structure, whereas ineffective restraint engagement increased the occupant excursion, resulting in a direct impact to the struck-side interior structures.

Functional Neuronal Processing of Human Body Odors

PubMed Central

Lundström, Johan N.; Olsson, Mats J.

2013-01-01

Body odors carry informational cues of great importance for individuals across a wide range of species, and signals hidden within the body odor cocktail are known to regulate several key behaviors in animals. For a long time, the notion that humans may be among these species has been dismissed. We now know, however, that each human has a unique odor signature that carries information related to his or her genetic makeup, as well as information about personal environmental variables, such as diet and hygiene. Although a substantial number of studies have investigated the behavioral effects of body odors, only a handful have studied central processing. Recent studies have, however, demonstrated that the human brain responds to fear signals hidden within the body odor cocktail, is able to extract kin specific signals, and processes body odors differently than other perceptually similar odors. In this chapter, we provide an overview of the current knowledge of how the human brain processes body odors and the potential importance these signals have for us in everyday life. PMID:20831940

Entropy flow and entropy production in the human body in basal conditions.

PubMed

Aoki, I

1989-11-08

Entropy inflow and outflow for the naked human body in basal conditions in the respiration calorimeter due to infrared radiation, convection, evaporation of water and mass-flow are calculated by use of the energetic data obtained by Hardy & Du Bois. Also, the change of entropy content in the body is estimated. The entropy production in the human body is obtained as the change of entropy content minus the net entropy flow into the body. The entropy production thus calculated becomes positive. The magnitude of entropy production per effective radiating surface area does not show any significant variation with subjects. The entropy production is nearly constant at the calorimeter temperatures of 26-32 degrees C; the average in this temperature range is 0.172 J m-2 sec-1 K-1. The forced air currents around the human body and also clothing have almost no effect in changing the entropy production. Thus, the entropy production of the naked human body in basal conditions does not depend on its environmental factors.

Building "Bob": A Project Exploring the Human Body at Western Illinois University Preschool Center

ERIC Educational Resources Information Center

Brouette, Scott

2008-01-01

When the children at Western Illinois University Preschool Center embarked on a study of human bodies, they decided to build a life-size model of a body, organ by organ from the inside out, to represent some of the things they were learning. This article describes the building of "Bob," the human body model, highlighting the children's…

Characterisation of the human-seat coupling in response to vibration.

PubMed

Kim, Eunyeong; Fard, Mohammad; Kato, Kazuhito

2017-08-01

Characterising the coupling between the occupant and vehicle seat is necessary to understand the transmission of vehicle seat vibration to the human body. In this study, the vibration characteristics of the human body coupled with a vehicle seat were identified in frequencies up to 100 Hz. Transmissibilities of three volunteers seated on two different vehicle seats were measured under multi-axial random vibration excitation. The results revealed that the human-seat system vibration was dominated by the human body and foam below 10 Hz. Major coupling between the human body and the vehicle seat-structure was observed in the frequency range of 10-60 Hz. There was local coupling of the system dominated by local resonances of seat frame and seat surface above 60 Hz. Moreover, the transmissibility measured on the seat surface between the human and seat foam is suggested to be a good method of capturing human-seat system resonances rather than that measured on the human body in high frequencies above 10 Hz.Practitioner Summary: The coupling characteristics of the combined human body and vehicle seat system has not yet been fully understood in frequencies of 0.5-100 Hz. This study shows the human-seat system has distinctive dynamic coupling characteristics in three different frequency regions: below 10 Hz, 10-60 Hz, and above 60 Hz.

Normative aspects of the human body.

PubMed

Siep, Ludwig

2003-04-01

In cultural history the human body has been the object of a great variety of opposing valuations, ranging from "imago dei" to "the devil's tool". At present, the body is commonly regarded as a mere means to fulfill the wishes of its "owner". According to these wishes it can be technically improved in an unlimited way. Against this view the text argues for a conception of the human body as a valuable "common heritage". The "normal" human body as the result of natural and cultural history is an essential condition of the modern social and legal order. The consequences of its technical alteration should be the subject of public debates and common decisions.

Analysis of Human Swing Movement and Transferring into Robot

NASA Astrophysics Data System (ADS)

Shimodaira, Jun; Amaoka, Yuki; Hamatani, Shinsuke; Takeuchi, Masahiro; Hirai, Hiroaki; Miyazaki, Fumio

Based on Generalized Motor Program, we analyzed the skill of human's table-tennis movement We hypothesized that it can be divided into arm swing and translational movements by upper and lower body movements, respectively. We expressed 3D position of the racket by only one parameter resulted from the analysis using Principal Component Analysis. Body trunk position measurement attested the lower body plays the role of keeping fixed relative-position between the ball and the body trunk at any hitting time. By applying human skills in upper and lower body movements, we could make the robot properly play table-tennis with a human.

Motor imagery of body movements that can't be executed on Earth.

PubMed

Kalicinski, Michael; Bock, Otmar; Schott, Nadja

2017-01-01

Before participating in a space mission, astronauts undergo parabolic-flight and underwater training to facilitate their subsequent adaptation to weightlessness. A quick, simple and inexpensive alternative could be training by motor imagery (MI). An important prerequisite for this training approach is that humans are able to imagine movements which are unfamiliar, since they can't be performed in the presence of gravity. Our study addresses this prerequisite. 68 young subjects completed a modified version of the CMI test (Schott, 2013). With eyes closed, subjects were asked to imagine moving their body according to six consecutive verbal instructions. After the sixth instruction, subjects opened their eyes and arranged the segments of a manikin into the assumed final body configuration. In a first condition, subjects received instructions only for moving individual body segments (CMIground). In a second condition, subjects received instructions for moving body segments or their full body (CMIfloat). After each condition, subjects were asked to rate their subjective visual and kinesthetic vividness of MI. Condition differences emerged for the CMI scores and for the duration of correct trials with better performance in the CMIground condition. Condition differences were also represented for the subjective MI performance. Motor imagery is possible but degraded when subjects are asked to imagine body movements while floating. This confirms that preflight training of MI while floating might be beneficial for astronauts' mission performance.

The Ownership of Human Body: An Islamic Perspective

PubMed Central

Aramesh, Kiarash

2009-01-01

Using human dead body for medical purposes is a common practice in medical schools and hospitals throughout the world. Iran, as an Islamic country is not an exception. According to the Islamic view, the body, like the soul, is a “gift” from God; therefore, human being does not possess absolute ownership on his or her body. But, the ownership of human beings on their bodies can be described as a kind of “stewardship”. Accordingly, any kind of dissection or mutilation of the corpse is forbidden, even with the informed consent of the dead or his/her relatives. The exception of this principle is when such procedures are necessary for saving lives of other persons. In this article using the human dead body for medical education, research and treatment is discussed and the perspective of Iranian Shiite religious scholars in this regard is explained. PMID:23908718

"Scientific peep show": the human body in contemporary science museums.

PubMed

Canadelli, Elena

2011-01-01

The essay focuses on the discourse about the human body developed by contemporary science museums with educational and instructive purposes directed at the general public. These museums aim mostly at mediating concepts such as health and prevention. The current scenario is linked with two examples of past museums: the popular anatomical museums which emerged during the 19th century and the health museums thrived between 1910 and 1940. On the museological path about the human body self-care we went from the emotionally involving anatomical Venuses to the inexpressive Transparent Man, from anatomical specimens of ill organs and deformed subjects to the mechanical and electronic models of the healthy body. Today the body is made transparent by the new medical diagnostics and by the latest discoveries of endoscopy. The way museums and science centers presently display the human body involves computers, 3D animation, digital technologies, hands-on models of large size human parts.

Body donations today and tomorrow: What is best practice and why?

PubMed

Riederer, Beat M

2016-01-01

There is considerable agreement that the use of human bodies for teaching and research remains important, yet not all universities use dissection to teach human gross anatomy. The concept of body donation has evolved over centuries and there are still considerable discrepancies among countries regarding the means by which human bodies are acquired and used for education and research. Many countries have well-established donation programs and use body dissection to teach most if not all human gross anatomy. In contrast, there are countries without donation programs that use unclaimed bodies or perhaps a few donated bodies instead. In several countries, use of cadavers for dissection is unthinkable for cultural or religious reasons. Against this background, successful donation programs are highlighted in the present review, emphasizing those aspects of the programs that make them successful. Looking to the future, we consider what best practice could look like and how the use of unclaimed bodies for anatomy teaching could be replaced. From an ethical point of view, countries that depend upon unclaimed bodies of dubious provenance are encouraged to use these reports and adopt strategies for developing successful donation programs. In many countries, the act of body donation has been guided by laws and ethical frameworks and has evolved alongside the needs for medical knowledge and for improved teaching of human anatomy. There will also be a future need for human bodies to ensure optimal pre- and post-graduate training and for use in biomedical research. Good body donation practice should be adopted wherever possible, moving away from the use of unclaimed bodies of dubious provenance and adopting strategies to favor the establishment of successful donation programs. © 2015 Wiley Periodicals, Inc.

Cislunar Near Rectilinear Halo Orbit for Human Space Exploration

NASA Technical Reports Server (NTRS)

Whitley, Ryan; Martinez, Roland; Condon, Gerald; Williams, Jacob; Lee, David; Davis, Diane; Barton, Gregg; Bhatt, Sagar; Jang, Jiann-Woei; Clark, Fred;

A novel manipulation method of human body ownership using an fMRI-compatible master-slave system.

PubMed

Hara, Masayuki; Salomon, Roy; van der Zwaag, Wietske; Kober, Tobias; Rognini, Giulio; Nabae, Hiroyuki; Yamamoto, Akio; Blanke, Olaf; Higuchi, Toshiro

2014-09-30

Bodily self-consciousness has become an important topic in cognitive neuroscience aiming to understand how the brain creates a unified sensation of the self in a body. Specifically, full body illusion (FBI) in which changes in bodily self-consciousness are experimentally introduced by using visual-tactile stimulation has led to improve understanding of these mechanisms. This paper introduces a novel approach to the classic FBI paradigm using a robotic master-slave system which allows us to examine interactions between action and the sense of body ownership in behavioral and MRI experiments. In the proposed approach, the use of the robotic master-slave system enables unique stimulation in which experimental participants can administer tactile cues on their own back using active self-touch. This active self-touch has never been employed in FBI experiments and it allows to test the role of sensorimotor integration and agency (the feeling of control over our actions) in FBI paradigms. The objective of this study is to propose a robotic-haptic platform allowing a new FBI paradigm including the active self-touch in MRI environments. This paper, first, describes the design concept and the performance of the prototype device in the fMRI environment (for 3T and 7T MRI scanners). In addition, the prototype device is applied to a classic FBI experiment, and we verify that the use of the prototype device succeeded in inducing the FBI. These results indicate that the proposed approach has a potential to drive advances in our understanding of human body ownership and agency by allowing novel manipulation and paradigms. Copyright © 2014 Elsevier B.V. All rights reserved.

Person Recognition System Based on a Combination of Body Images from Visible Light and Thermal Cameras.

PubMed

Nguyen, Dat Tien; Hong, Hyung Gil; Kim, Ki Wan; Park, Kang Ryoung

2017-03-16

The human body contains identity information that can be used for the person recognition (verification/recognition) problem. In this paper, we propose a person recognition method using the information extracted from body images. Our research is novel in the following three ways compared to previous studies. First, we use the images of human body for recognizing individuals. To overcome the limitations of previous studies on body-based person recognition that use only visible light images for recognition, we use human body images captured by two different kinds of camera, including a visible light camera and a thermal camera. The use of two different kinds of body image helps us to reduce the effects of noise, background, and variation in the appearance of a human body. Second, we apply a state-of-the art method, called convolutional neural network (CNN) among various available methods, for image features extraction in order to overcome the limitations of traditional hand-designed image feature extraction methods. Finally, with the extracted image features from body images, the recognition task is performed by measuring the distance between the input and enrolled samples. The experimental results show that the proposed method is efficient for enhancing recognition accuracy compared to systems that use only visible light or thermal images of the human body.

Adjustments to de Leva-anthropometric regression data for the changes in body proportions in elderly humans.

PubMed

Ho Hoang, Khai-Long; Mombaur, Katja

2015-10-15

Dynamic modeling of the human body is an important tool to investigate the fundamentals of the biomechanics of human movement. To model the human body in terms of a multi-body system, it is necessary to know the anthropometric parameters of the body segments. For young healthy subjects, several data sets exist that are widely used in the research community, e.g. the tables provided by de Leva. None such comprehensive anthropometric parameter sets exist for elderly people. It is, however, well known that body proportions change significantly during aging, e.g. due to degenerative effects in the spine, such that parameters for young people cannot be used for realistically simulating the dynamics of elderly people. In this study, regression equations are derived from the inertial parameters, center of mass positions, and body segment lengths provided by de Leva to be adjustable to the changes in proportion of the body parts of male and female humans due to aging. Additional adjustments are made to the reference points of the parameters for the upper body segments as they are chosen in a more practicable way in the context of creating a multi-body model in a chain structure with the pelvis representing the most proximal segment. Copyright © 2015 Elsevier Ltd. All rights reserved.

The Search for a Volatile Human Specific Marker in the Decomposition Process

PubMed Central

Rosier, E.; Loix, S.; Develter, W.; Van de Voorde, W.; Tytgat, J.; Cuypers, E.

2015-01-01

In this study, a validated method using a thermal desorber combined with a gas chromatograph coupled to mass spectrometry was used to identify the volatile organic compounds released during decomposition of 6 human and 26 animal remains in a laboratory environment during a period of 6 months. 452 compounds were identified. Among them a human specific marker was sought using principle component analysis. We found a combination of 8 compounds (ethyl propionate, propyl propionate, propyl butyrate, ethyl pentanoate, pyridine, diethyl disulfide, methyl(methylthio)ethyl disulfide and 3-methylthio-1-propanol) that led to the distinction of human and pig remains from other animal remains. Furthermore, it was possible to separate the pig remains from human remains based on 5 esters (3-methylbutyl pentanoate, 3-methylbutyl 3-methylbutyrate, 3-methylbutyl 2-methylbutyrate, butyl pentanoate and propyl hexanoate). Further research in the field with full bodies has to corroborate these results and search for one or more human specific markers. These markers would allow a more efficiently training of cadaver dogs or portable detection devices could be developed. PMID:26375029

The influence of a formula supplemented with dairy lipids and plant oils on the erythrocyte membrane omega-3 fatty acid profile in healthy full-term infants: a double-blind randomized controlled trial

PubMed Central

2012-01-01

Background Human milk is the optimal nutrition for infants. When breastfeeding is not possible, supplementation of infant formula with long chain polyunsaturated fatty acids appears to promote neurodevelopmental outcome and visual function. Plant oils, that are the only source of fat in most of infant formulas, do not contain specific fatty acids that are present in human and cow milk and do not encounter milk fat triglyceride structure. Experimental data suggest that a mix of dairy lipids and plant oils can potentiate endogenous synthesis of n-3 long chain polyunsaturated fatty acids. This trial aims to determine the effect of an infant formula supplemented with a mixture of dairy lipids and plant oils on the erythrocyte membrane omega-3 fatty acid profile in full-term infants (primary outcome). Erythrocyte membrane long chain polyunsaturated fatty acids and fatty acids content, the plasma lipid profile and the insulin-growth factor 1 level, the gastrointestinal tolerance, the changes throughout the study in blood fatty acids content, in growth and body composition are evaluated as secondary outcomes. Methods/Design In a double-blind controlled randomized trial, 75 healthy full-term infants are randomly allocated to receive for four months a formula supplemented with a mixture of dairy lipids and plant oils or a formula containing only plant oils or a formula containing plant oils supplemented with arachidonic acid and docosahexaenoic acid. Twenty-five breast-fed infants constitute the reference group. Erythrocyte membrane omega-3 fatty acid profile, long chain polyunsaturated fatty acids and the other fatty acids content, the plasma lipid profile and the insulin-growth factor 1 level are measured after four months of intervention. Gastrointestinal tolerance, the changes in blood fatty acids content, in growth and body composition, assessed by means of an air displacement plethysmography system, are also evaluated throughout the study. Discussion The achievement of an appropriate long chain polyunsaturated fatty acids status represents an important goal in neonatal nutrition. Gaining further insight in the effects of the supplementation of a formula with dairy lipids and plant oils in healthy full-term infants could help to produce a formula whose fat content, composition and structure is more similar to human milk. Trial registration ClinicalTrials.gov Identifier NCT01611649 PMID:23072617

The influence of a formula supplemented with dairy lipids and plant oils on the erythrocyte membrane omega-3 fatty acid profile in healthy full-term infants: a double-blind randomized controlled trial.

PubMed

Giannì, Maria Lorella; Roggero, Paola; Baudry, Charlotte; Ligneul, Amandine; Morniroli, Daniela; Garbarino, Francesca; le Ruyet, Pascale; Mosca, Fabio

2012-10-17

Human milk is the optimal nutrition for infants. When breastfeeding is not possible, supplementation of infant formula with long chain polyunsaturated fatty acids appears to promote neurodevelopmental outcome and visual function. Plant oils, that are the only source of fat in most of infant formulas, do not contain specific fatty acids that are present in human and cow milk and do not encounter milk fat triglyceride structure. Experimental data suggest that a mix of dairy lipids and plant oils can potentiate endogenous synthesis of n-3 long chain polyunsaturated fatty acids. This trial aims to determine the effect of an infant formula supplemented with a mixture of dairy lipids and plant oils on the erythrocyte membrane omega-3 fatty acid profile in full-term infants (primary outcome). Erythrocyte membrane long chain polyunsaturated fatty acids and fatty acids content, the plasma lipid profile and the insulin-growth factor 1 level, the gastrointestinal tolerance, the changes throughout the study in blood fatty acids content, in growth and body composition are evaluated as secondary outcomes. In a double-blind controlled randomized trial, 75 healthy full-term infants are randomly allocated to receive for four months a formula supplemented with a mixture of dairy lipids and plant oils or a formula containing only plant oils or a formula containing plant oils supplemented with arachidonic acid and docosahexaenoic acid. Twenty-five breast-fed infants constitute the reference group. Erythrocyte membrane omega-3 fatty acid profile, long chain polyunsaturated fatty acids and the other fatty acids content, the plasma lipid profile and the insulin-growth factor 1 level are measured after four months of intervention. Gastrointestinal tolerance, the changes in blood fatty acids content, in growth and body composition, assessed by means of an air displacement plethysmography system, are also evaluated throughout the study. The achievement of an appropriate long chain polyunsaturated fatty acids status represents an important goal in neonatal nutrition. Gaining further insight in the effects of the supplementation of a formula with dairy lipids and plant oils in healthy full-term infants could help to produce a formula whose fat content, composition and structure is more similar to human milk. ClinicalTrials.gov Identifier NCT01611649.

A study and comparison of the effects of low speed change vehicle collisions on the human body.

PubMed

Hoyes, Philip; Henderson, Brian

2013-03-01

In motor vehicle collisions there is a well-established relationship between the level of damage sustained by the vehicle, its change in speed during the collision period, the movement of occupants and the potential for their injury. Greater damage, with respect to structure, means a greater potential for injury. In terms of rear-end impacts, speed change thresholds for injury have been suggested in previous literature. This research uses human test subjects and three full-scale vehicle, rear-end collisions to investigate the correlation between speed change and occupant movement and uses it to test the suggestion of a second threshold where the accelerations are similar to an everyday activity. Copyright © 2012 Elsevier Ltd. All rights reserved.

Learning from regeneration research organisms: The circuitous road to scar free wound healing

PubMed Central

Erickson, Jami R.; Echeverri, Karen

2018-01-01

The skin is the largest organ in the body and plays multiple essential roles ranging from regulating temperature, preventing infection and ultimately defining who we are physically. It is a highly dynamic organ that constantly replaces the outermost cells throughout life. However, when faced with a major injury, human skin cannot restore a significant lesion to its original functionality, instead a reparative scar is formed. In contrast to this, many other species have the unique ability to regenerate full thickness skin without formation of scar tissue. Here we review recent advances in the field that shed light on how the skin cells in regenerative species react to injury to prevent scar formation versus scar forming humans. PMID:29179946

Analysis of Timing Control Mechanism of Utterance and Body Motion Using Dialogue between Human and Communication Robot

NASA Astrophysics Data System (ADS)

Takasugi, Shoji; Yamamoto, Tomohito; Muto, Yumiko; Abe, Hiroyuki; Miyake, Yoshihiro

The purpose of this study is to clarify the effects of timing control of utterance and body motion in human-robot interaction. Our previous study has already revealed the correlation of timing of utterance and body motion in human-human communication. Here we proposed a timing control model based on our previous research and estimated its influence to realize human-like communication using a questionnaire method. The results showed that the difference of effectiveness between the communication with the timing control model and that without it was observed. In addition, elderly people evaluated the communication with timing control much higher than younger people. These results show not only the importance of timing control of utterance and body motion in human communication but also its effectiveness for realizing human-like human-robot interaction.

36 CFR 2.14 - Sanitation and refuse.

Code of Federal Regulations, 2010 CFR

2010-07-01

... human body waste, except at designated locations or in fixtures provided for that purpose. (9) In nondeveloped areas, the disposal of human body waste within 100 feet of a water source, high water mark of a... superintendent may establish conditions concerning the disposal, containerization, or carryout of human body...

36 CFR 2.14 - Sanitation and refuse.

Code of Federal Regulations, 2011 CFR

2011-07-01

... human body waste, except at designated locations or in fixtures provided for that purpose. (9) In nondeveloped areas, the disposal of human body waste within 100 feet of a water source, high water mark of a... superintendent may establish conditions concerning the disposal, containerization, or carryout of human body...

Infants' knowledge of their own species

PubMed Central

Heron-Delaney, Michelle; Wirth, Sylvia; Pascalis, Olivier

2011-01-01

Recognition of individuals at first sight is important for social species and can be achieved by attending to facial or body information. Previous research suggests that infants possess a perceptual template for evolutionarily relevant stimuli, which may include humans, dangerous animals (e.g. snakes), but not non-dangerous animals. To be effective, such a mechanism should result in a systematic preference for attending to humans over non-dangerous animals. Using a preferential looking paradigm, the present studies investigated the nature of infants' early representation of humans. We show that 3.5- and six-month-old infants attend more to human beings than non-human primates (a gorilla or monkey) which are examplars of non-dangerous animals. This occurred when infants were presented with head or body information in isolation, as well as when both are presented simultaneously. This early preference for humans by 3.5 months of age suggests that there is a basic representation for humans, which includes both head and/or body information. However, neonates demonstrated a preference only for human faces over non-human primate faces, not for humans over non-human primates when the stimuli were presented with both head and body simultaneously. The results show that although neonates display a preference for human faces over others, preference for the human body only develops later, in the first few months of life. This suggests that infants have acquired some knowledge about the human body at 3.5 months of age that may have developed from their privileged experience with other humans in the first few months of life, rather than an innate ability to detect humans in their entirety. PMID:21536558

Digitization of the human body in the present-day economy

NASA Astrophysics Data System (ADS)

D'Apuzzo, Nicola

2004-12-01

In this paper we report on the historic development of human body digitization and on the actual state of commercially available technology. Complete systems for the digitization of the human body exist since more than ten years. One of the main users of this technology was the entertainment industry. Every new movie excited with attractive visual effects, but only few people knew that the most thrilling cuts were realized by using virtual persons. The faces and bodies of actors were digitized and the "virtual twin" replaced the actor in the movie. Nowadays, the state of the human body digitization is so high that it is not possible any more to distinguish the real actor from the virtual one. Indeed, for the rush technical development has to be thanked the movie industry, which was one of the strong economic motors for this technology. Today, with the possibility of a massive cost reduction given by new technologies, methods for digitization of the human body are used also in other fields of application, such as ergonomics, medical applications, computer games, biometry and anthropometrics. With the time, this technology becomes interesting also for sport, fitness, fashion and beauty. A large expansion of human body digitization is expected in the near future. To date, different technologies are used commercially for the measurement of the human body. They can be divided into three distinguished groups: laser-scanning, projection of light patterns, combination modeling and image processing. The different solutions have strengths and weaknesses that profile their suitability for specific applications. This paper gives an overview of their differences and characteristics and expresses clues for the selection of the adequate method. Practical examples of commercial exploitation of human body digitization are also presented and new interesting perspectives are introduced.

Digitization of the human body in the present-day economy

NASA Astrophysics Data System (ADS)

D'Apuzzo, Nicola

2005-01-01

In this paper we report on the historic development of human body digitization and on the actual state of commercially available technology. Complete systems for the digitization of the human body exist since more than ten years. One of the main users of this technology was the entertainment industry. Every new movie excited with attractive visual effects, but only few people knew that the most thrilling cuts were realized by using virtual persons. The faces and bodies of actors were digitized and the "virtual twin" replaced the actor in the movie. Nowadays, the state of the human body digitization is so high that it is not possible any more to distinguish the real actor from the virtual one. Indeed, for the rush technical development has to be thanked the movie industry, which was one of the strong economic motors for this technology. Today, with the possibility of a massive cost reduction given by new technologies, methods for digitization of the human body are used also in other fields of application, such as ergonomics, medical applications, computer games, biometry and anthropometrics. With the time, this technology becomes interesting also for sport, fitness, fashion and beauty. A large expansion of human body digitization is expected in the near future. To date, different technologies are used commercially for the measurement of the human body. They can be divided into three distinguished groups: laser-scanning, projection of light patterns, combination modeling and image processing. The different solutions have strengths and weaknesses that profile their suitability for specific applications. This paper gives an overview of their differences and characteristics and expresses clues for the selection of the adequate method. Practical examples of commercial exploitation of human body digitization are also presented and new interesting perspectives are introduced.

Three-dimensional surface anthropometry: Applications to the human body

NASA Astrophysics Data System (ADS)

Jones, Peter R. M.; Rioux, Marc

1997-09-01

Anthropometry is the study of the measurement of the human body. By tradition this has been carried out taking the measurements from body surface landmarks, such as circumferences and breadths, using simple instruments like tape measures and calipers. Three-dimensional (3D) surface anthropometry enables us to extend the study to 3D geometry and morphology of mainly external human body tissues. It includes the acquisition, indexing, transmission, archiving, retrieval, interrogation and analysis of body size, shape, and surface together with their variability throughout growth and development to adulthood. While 3D surface anthropometry surveying is relatively new, anthropometric surveying using traditional tools, such as calipers and tape measures, is not. Recorded studies of the human form date back to ancient times. Since at least the 17th century 1 investigators have made attempts to measure the human body for physical properties such as weight, size, and centre of mass. Martin documented 'standard' body measurement methods in a handbook in 1928. 2 This paper reviews the past and current literature devoted to the applications of 3D anthropometry because true 3D scanning of the complete human body is fast becoming a reality. We attempt to take readers through different forms of technology which deal with simple forms of projected light to the more complex advanced forms of laser and video technology giving low and/or high resolution 3D data. Information is also given about image capture of size and shape of the whole as well as most component parts of the human body. In particular, the review describes with explanations a multitude of applications, for example, medical, product design, human engineering, anthropometry and ergonomics etc.

Effect of clothing material on thermal responses of the human body

NASA Astrophysics Data System (ADS)

Fengzhi, Li; Yi, Li

2005-09-01

The influence of clothing material on thermal responses of the human body are investigated by using an integrated model of a clothed thermoregulatory human body. A modified 25-nodes model considering the sweat accumulation on the skin surface is applied to simulate the human physiological regulatory responses. The heat and moisture coupled transfer mechanisms, including water vapour diffusion, the moisture evaporation/condensation, the moisture sorbtion/desorption by fibres, liquid sweat transfer under capillary pressure, and latent heat absorption/release due to phase change, are considered in the clothing model. On comparing prediction results with the experimental data in the literature, the proposed model seems able to predict dynamic heat and moisture transfer between the human body and the clothing system. The human body's thermal responses and clothing temperature and moisture variations are compared for different clothing materials during transient periods. We concluded that the hygroscopicity of clothing materials influences the human thermoregulation process significantly during environmental transients.

Experimental investigation of biodynamic human body models subjected to whole-body vibration during a vehicle ride.

PubMed

Taskin, Yener; Hacioglu, Yuksel; Ortes, Faruk; Karabulut, Derya; Arslan, Yunus Ziya

2018-02-06

In this study, responses of biodynamic human body models to whole-body vibration during a vehicle ride were investigated. Accelerations were acquired from three different body parts, such as the head, upper torso and lower torso, of 10 seated passengers during a car ride while two different road conditions were considered. The same multipurpose vehicle was used during all experiments. Additionally, by two widely used biodynamic models in the literature, a set of simulations were run to obtain theoretical accelerations of the models and were compared with those obtained experimentally. To sustain a quantified comparison between experimental and theoretical approaches, the root mean square acceleration and acceleration spectral density were calculated. Time and frequency responses of the models demonstrated that neither of the models showed the best prediction performance of the human body behaviour in all cases, indicating that further models are required for better prediction of the human body responses.

International Human Rights and the Mistreatment of Women During Childbirth

PubMed Central

Zampas, Christina; Vogel, Joshua P.; Bohren, Meghan A.; Roseman, Mindy; Erdman, Joanna N.

2016-01-01

Abstract International human rights bodies have played a critical role in codifying, setting standards, and monitoring human rights violations in the context of sexual and reproductive health and rights. In recent years, these institutions have developed and applied human rights standards in the more particular context of maternal mortality and morbidity, and have increasingly recognized a critical human rights issue in the provision and experience of care during and after pregnancy, including during childbirth. However, the international human rights standards on mistreatment during facility-based childbirth remain, in an early stage of development, focused largely on a discrete subset of experiences, such as forced sterilization and lack of access to emergency obstetric care. As a consequence, the range of mistreatment that women may experience has not been adequately addressed or analyzed under international human rights law. Identifying human rights norms and standards related to the full range of documented mistreatment is thus a first step towards addressing violations of human rights during facility-based childbirth, ensuring respectful and humane treatment, and developing a program of work to improve the overall quality of maternal care. This article reviews international human rights standards related to the mistreatment of women during childbirth in facility settings under regional and international human rights law and lays out an agenda for further research and action. PMID:28559681

International Human Rights and the Mistreatment of Women During Childbirth.

PubMed

Khosla, Rajat; Zampas, Christina; Vogel, Joshua P; Bohren, Meghan A; Roseman, Mindy; Erdman, Joanna N

2016-12-01

International human rights bodies have played a critical role in codifying, setting standards, and monitoring human rights violations in the context of sexual and reproductive health and rights. In recent years, these institutions have developed and applied human rights standards in the more particular context of maternal mortality and morbidity, and have increasingly recognized a critical human rights issue in the provision and experience of care during and after pregnancy, including during childbirth. However, the international human rights standards on mistreatment during facility-based childbirth remain, in an early stage of development, focused largely on a discrete subset of experiences, such as forced sterilization and lack of access to emergency obstetric care. As a consequence, the range of mistreatment that women may experience has not been adequately addressed or analyzed under international human rights law. Identifying human rights norms and standards related to the full range of documented mistreatment is thus a first step towards addressing violations of human rights during facility-based childbirth, ensuring respectful and humane treatment, and developing a program of work to improve the overall quality of maternal care. This article reviews international human rights standards related to the mistreatment of women during childbirth in facility settings under regional and international human rights law and lays out an agenda for further research and action.

An attempt to model the human body as a communication channel.

PubMed

Wegmueller, Marc Simon; Kuhn, Andreas; Froehlich, Juerg; Oberle, Michael; Felber, Norbert; Kuster, Niels; Fichtner, Wolfgang

2007-10-01

Using the human body as a transmission medium for electrical signals offers novel data communication in biomedical monitoring systems. In this paper, galvanic coupling is presented as a promising approach for wireless intra-body communication between on-body sensors. The human body is characterized as a transmission medium for electrical current by means of numerical simulations and measurements. Properties of dedicated tissue layers and geometrical body variations are investigated, and different electrodes are compared. The new intra-body communication technology has shown its feasibility in clinical trials. Excellent transmission was achieved between locations on the thorax with a typical signal-to-noise ratio (SNR) of 20 dB while the attenuation increased along the extremities.

Where is your shoulder? Neural correlates of localizing others' body parts.

PubMed

Felician, Olivier; Anton, Jean-Luc; Nazarian, Bruno; Roth, Muriel; Roll, Jean-Pierre; Romaiguère, Patricia

2009-07-01

Neuropsychological studies, based on pointing to body parts paradigms, suggest that left posterior parietal lobe is involved in the visual processing of other persons' bodies. In addition, some patients have been found with mild deficit when dealing with abstract human representations but marked impairment with realistically represented bodies, suggesting that this processing could be modulated by the abstraction level of the body to be analyzed. These issues were examined in the present fMRI experiment, designed to evaluate the effects of visually processing human bodies of different abstraction levels on brain activity. The human specificity of the studied processes was assessed using whole-body representations of humans and of dogs, while the effects of the abstraction level of the representation were assessed using drawings, photographs, and videos. To assess the effect of species and stimulus complexity on BOLD signal, we performed a two-way ANOVA with factors species (human versus animal) and stimulus complexity (drawings, photographs and videos). When pointing to body parts irrespective of the stimulus complexity, we observed a positive effect of humans upon animals in the left angular gyrus (BA 39), as suggested by lesion studies. This effect was also present in midline cortical structures including mesial prefrontal, anterior cingulate and precuneal regions. When pointing to body parts irrespective of the species to be processed, we observed a positive effect of videos upon photographs and drawings in the right superior parietal lobule (BA 7), and bilaterally in the superior temporal sulcus, the supramarginal gyrus (BA 40) and the lateral extrastriate visual cortex (including the "extrastriate body area"). Taken together, these data suggest that, in comparison with other mammalians, the visual processing of other humans' bodies is associated with left angular gyrus activity, but also with midline structures commonly implicated in self-reference. They also suggest a role of the lateral extrastriate cortex in the processing of dynamic and biologically relevant body representations.

The personification of animals: coding of human and nonhuman body parts based on posture and function.

PubMed

Welsh, Timothy N; McDougall, Laura; Paulson, Stephanie

2014-09-01

The purpose of the present research was to determine how humans represent the bodies and limbs of nonhuman mammals based on anatomical and functional properties. To this end, participants completed a series of body-part compatibility tasks in which they responded with a thumb or foot response to the color of a stimulus (red or blue, respectively) presented on different limbs of several animals. Across the studies, this compatibility task was conducted with images of human and nonhuman animals (bears, cows, and monkeys) in bipedal or quadrupedal postures. The results revealed that the coding of the limbs of nonhuman animals is strongly influenced by the posture of the body, but not the functional capacity of the limb. Specifically, body-part compatibility effects were present for both human and nonhuman animals when the figures were in a bipedal posture, but were not present when the animals were in a quadrupedal stance (Experiments 1a-c). Experiments 2a and 2b revealed that the posture-based body-part compatibility effects were not simply a vertical spatial compatibility effect or due to a mismatch between the posture of the body in the image and the participant. These data indicate that nonhuman animals in a bipedal posture are coded with respect to the "human" body representation, whereas nonhuman animals in a quadrupedal posture are not mapped to the human body representation. Overall, these studies provide new insight into the processes through which humans understand, mimic, and learn from the actions of nonhuman animals. Copyright © 2014 Elsevier B.V. All rights reserved.

An evaluation of objective rating methods for full-body finite element model comparison to PMHS tests.

PubMed

Vavalle, Nicholas A; Jelen, Benjamin C; Moreno, Daniel P; Stitzel, Joel D; Gayzik, F Scott

2013-01-01

Objective evaluation methods of time history signals are used to quantify how well simulated human body responses match experimental data. As the use of simulations grows in the field of biomechanics, there is a need to establish standard approaches for comparisons. There are 2 aims of this study. The first is to apply 3 objective evaluation methods found in the literature to a set of data from a human body finite element model. The second is to compare the results of each method, examining how they are correlated to each other and the relative strengths and weaknesses of the algorithms. In this study, the methods proposed by Sprague and Geers (magnitude and phase error, SGM and SGP), Rhule et al. (cumulative standard deviation, CSD), and Gehre et al. (CORrelation and Analysis, or CORA, size, phase, shape, corridor) were compared. A 40 kph frontal sled test presented by Shaw et al. was simulated using the Global Human Body Models Consortium midsized male full-body finite element model (v. 3.5). Mean and standard deviation experimental data (n = 5) from Shaw et al. were used as the benchmark. Simulated data were output from the model at the appropriate anatomical locations for kinematic comparison. Force data were output at the seat belts, seat pan, knee, and foot restraints. Objective comparisons from 53 time history data channels were compared to the experimental results. To compare the different methods, all objective comparison metrics were cross-plotted and linear regressions were calculated. The following ratings were found to be statistically significantly correlated (P < .01): SGM and CORrelation and Analysis (CORA) size, R (2) = 0.73; SGP and CORA shape, R (2) = 0.82; and CSD and CORA's corridor factor, R (2) = 0.59. Relative strengths of the correlated ratings were then investigated. For example, though correlated to CORA size, SGM carries a sign to indicate whether the simulated response is greater than or less than the benchmark signal. A further analysis of the advantages and drawbacks of each method is discussed. The results demonstrate that a single metric is insufficient to provide a complete assessment of how well the simulated results match the experiments. The CORA method provided the most comprehensive evaluation of the signal. Regardless of the method selected, one primary recommendation of this work is that for any comparison, the results should be reported to provide separate assessments of a signal's match to experimental variance, magnitude, phase, and shape. Future work planned includes implementing any forthcoming International Organization for Standardization standards for objective evaluations. Supplemental materials are available for this article. Go to the publisher's online edition of Traffic Injury Prevention to view the supplemental file.

[Human body meridian spatial decision support system for clinical treatment and teaching of acupuncture and moxibustion].

PubMed

Wu, Dehua

2016-01-01

The spatial position and distribution of human body meridian are expressed limitedly in the decision support system (DSS) of acupuncture and moxibustion at present, which leads to the failure to give the effective quantitative analysis on the spatial range and the difficulty for the decision-maker to provide a realistic spatial decision environment. Focusing on the limit spatial expression in DSS of acupuncture and moxibustion, it was proposed that on the basis of the geographic information system, in association of DSS technology, the design idea was developed on the human body meridian spatial DSS. With the 4-layer service-oriented architecture adopted, the data center integrated development platform was taken as the system development environment. The hierarchical organization was done for the spatial data of human body meridian via the directory tree. The structured query language (SQL) server was used to achieve the unified management of spatial data and attribute data. The technologies of architecture, configuration and plug-in development model were integrated to achieve the data inquiry, buffer analysis and program evaluation of the human body meridian spatial DSS. The research results show that the human body meridian spatial DSS could reflect realistically the spatial characteristics of the spatial position and distribution of human body meridian and met the constantly changeable demand of users. It has the powerful spatial analysis function and assists with the scientific decision in clinical treatment and teaching of acupuncture and moxibustion. It is the new attempt to the informatization research of human body meridian.

Commentary: is totipotency of a human cell a sufficient reason to exclude its patentability under the European law?

PubMed

Vrtovec, Katja Triller; Vrtovec, Bojan

2007-12-01

This article argues that totipotent character of human totipotent cells--defined as the capacity of a cell "to differentiate into all somatic lineages (ectoderm, mesoderm, endoderm), the germ line and extra-embryonic tissues such as the placenta"--is not a sufficient reason to exclude their patentability on the basis of Article 5(1) of the Directive 98/44/EC on the Legal Protection of Biotechnological Inventions (Biopatent Directive), which maintains that "the human body, at the various stages of its formation and development, [...] cannot constitute patentable inventions." Since human totipotent cells have both the potential to generate an entire new organism or to generate only different tissues or organs of an organism, they simultaneously fit the definition of the unpatentable human body at the earliest stage of its formation as well as of an element of the human body, which "may constitute a patentable invention" pursuant to Article 5(2) of the Biopatent Directive, whether that element is isolated from the human body or otherwise produced by means of a technical process. Therefore, this article suggests that, when evaluating patentability of human totipotent cells, they should be further evaluated according to their location and their method of derivation (i.e., whether human totipotent cells are located in the human body, whether they are isolated from the human body, or whether they are produced otherwise by means of a technical process). Disclosure of potential conflicts of interest is found at the end of this article.

Cyborg identities and contemporary techno-utopias: adaptations and transformations of the body in the age of nanotechnology.

PubMed

Maestrutti, Marina

2011-01-01

The possibility of improving the human body through a closer relationship with technology in order to overcome the human species toward new stages of evolution is a constant element of techno-utopian visions, among other transhumanism. This projection to a radical transformation of the body - and mind - as a result of technological action is based on the concepts of adaptation, or non adaptation, of a human being to a world constantly changed by technoscience. The belief is that not only the body has to change, but that identity is not a stable concept. This mobility in the relationship between body and identity is typical of the post human thought, which inherits from the informational model the conviction that the biological embodiment of human is to be regarded as an accident of history rather than as an essential condition of life. Hybridization is therefore valued by the post human thought as a condition which has "made" the human as he is today, and it appears as a fundamental topic in any discourse on nanotechnology, biotechnology and development of human-machine interfaces.

Perception and description of New World non-human primates in the travel literature of the fifteenth and sixteenth centuries: a critical review.

PubMed

Veracini, Cecilia; Teixeira, Dante Martins

2017-01-01

The current work presents the results of a review of most of the European diaries and travel chronicles containing reports of New World non-human primates dating from the discovery of America in 1492 until the end of the sixteenth century. We report the integral texts translated into English of these literary sources, giving a critical interpretation from a historical and scientific point of view. We note the ways these primates were perceived and described, with attention to the most important characteristics that were highlighted by the first explorers. Ethnotaxonomy and vernacular names used to designate non-human primates are also provided. This new body of knowledge, based largely on empirical reports full of details and first-hand observations, emerged as the first nucleus in the natural history of Neotropical Primates.

21 CFR 821.3 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-04-01

... or long-term injuries or illnesses. (f) Device intended to be implanted in the human body for more... of the human body for more than 1 year to continuously assist, restore, or replace the function of an organ system or structure of the human body throughout the useful life of the device. The term does not...

21 CFR 71.20 - Publication of regulation.

Code of Federal Regulations, 2010 CFR

2010-04-01

... on foods, drugs, or cosmetics or for use in coloring the human body, as the case may be, or may... which such color additive may be used, or for the material intended for coloring the human body; the... food, drug, or cosmetic or article intended for coloring the human body; the manner in which such color...

76 FR 25236 - Carbon Dioxide; Exemption From the Requirement of a Tolerance

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-04

... metabolism and is always present in the body at about 6 percent concentration. An average adult human will... Departure/Levels of Concern Considering its presence in the environment and in the human body, the... the amount of carbon dioxide naturally produced by the human body each day. 2. Non-dietary exposure...

21 CFR 71.20 - Publication of regulation.

Code of Federal Regulations, 2011 CFR

2011-04-01

... on foods, drugs, or cosmetics or for use in coloring the human body, as the case may be, or may... which such color additive may be used, or for the material intended for coloring the human body; the... food, drug, or cosmetic or article intended for coloring the human body; the manner in which such color...

21 CFR 821.3 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-04-01

... or long-term injuries or illnesses. (f) Device intended to be implanted in the human body for more... of the human body for more than 1 year to continuously assist, restore, or replace the function of an organ system or structure of the human body throughout the useful life of the device. The term does not...

[A cyborg is only human].

PubMed

Schermer, Maartje H N

2013-01-01

New biomedical technologies make it possible to replace parts of the human body or to substitute its functions. Examples include artificial joints, eye lenses and arterial stents. Newer technologies use electronics and software, for example in brain-computer interfaces such as retinal implants and the exoskeleton MindWalker. Gradually we are creating cyborgs: hybrids of man and machine. This raises the question: are cyborgs still humans? It is argued that they are. First, because employing technology is a typically human characteristic. Second, because in western thought the human mind, and not the body, is considered to be the seat of personhood. However, it has been argued by phenomenological philosophers that the body is more than just an object but is also a subject, important for human identity. From this perspective, we can appreciate that a bionic body does not make one less human, but it does influence the experience of being human.

Hierarchical human action recognition around sleeping using obscured posture information

NASA Astrophysics Data System (ADS)

Kudo, Yuta; Sashida, Takehiko; Aoki, Yoshimitsu

2015-04-01

This paper presents a new approach for human action recognition around sleeping with the human body parts locations and the positional relationship between human and sleeping environment. Body parts are estimated from the depth image obtained by a time-of-flight (TOF) sensor using oriented 3D normal vector. Issues in action recognition of sleeping situation are the demand of availability in darkness, and hiding of the human body by duvets. Therefore, the extraction of image features is difficult since color and edge features are obscured by covers. Thus, first in our method, positions of four parts of the body (head, torso, thigh, and lower leg) are estimated by using the shape model of bodily surface constructed by oriented 3D normal vector. This shape model can represent the surface shape of rough body, and is effective in robust posture estimation of the body hidden with duvets. Then, action descriptor is extracted from the position of each body part. The descriptor includes temporal variation of each part of the body and spatial vector of position of the parts and the bed. Furthermore, this paper proposes hierarchical action classes and classifiers to improve the indistinct action classification. Classifiers are composed of two layers, and recognize human action by using the action descriptor. First layer focuses on spatial descriptor and classifies action roughly. Second layer focuses on temporal descriptor and classifies action finely. This approach achieves a robust recognition of obscured human by using the posture information and the hierarchical action recognition.

Human body motion tracking based on quantum-inspired immune cloning algorithm

NASA Astrophysics Data System (ADS)

Han, Hong; Yue, Lichuan; Jiao, Licheng; Wu, Xing

2009-10-01

In a static monocular camera system, to gain a perfect 3D human body posture is a great challenge for Computer Vision technology now. This paper presented human postures recognition from video sequences using the Quantum-Inspired Immune Cloning Algorithm (QICA). The algorithm included three parts. Firstly, prior knowledge of human beings was used, the key joint points of human could be detected automatically from the human contours and skeletons which could be thinning from the contours; And due to the complexity of human movement, a forecasting mechanism of occlusion joint points was addressed to get optimum 2D key joint points of human body; And then pose estimation recovered by optimizing between the 2D projection of 3D human key joint points and 2D detection key joint points using QICA, which recovered the movement of human body perfectly, because this algorithm could acquire not only the global optimal solution, but the local optimal solution.

Functional neuronal processing of human body odors.

PubMed

Lundström, Johan N; Olsson, Mats J

2010-01-01

Body odors carry informational cues of great importance for individuals across a wide range of species, and signals hidden within the body odor cocktail are known to regulate several key behaviors in animals. For a long time, the notion that humans may be among these species has been dismissed. We now know, however, that each human has a unique odor signature that carries information related to his or her genetic makeup, as well as information about personal environmental variables, such as diet and hygiene. Although a substantial number of studies have investigated the behavioral effects of body odors, only a handful have studied central processing. Recent studies have, however, demonstrated that the human brain responds to fear signals hidden within the body odor cocktail, is able to extract kin specific signals, and processes body odors differently than other perceptually similar odors. In this chapter, we provide an overview of the current knowledge of how the human brain processes body odors and the potential importance these signals have for us in everyday life. Copyright © 2010 Elsevier Inc. All rights reserved.

[Clinical effect of three dimensional human body scanning system BurnCalc in the evaluation of burn wound area].

PubMed

Lu, J; Wang, L; Zhang, Y C; Tang, H T; Xia, Z F

2017-10-20

Objective: To validate the clinical effect of three dimensional human body scanning system BurnCalc developed by our research team in the evaluation of burn wound area. Methods: A total of 48 burn patients treated in the outpatient department of our unit from January to June 2015, conforming to the study criteria, were enrolled in. For the first 12 patients, one wound on the limbs or torso was selected from each patient. The stability of the system was tested by 3 attending physicians using three dimensional human body scanning system BurnCalc to measure the area of wounds individually. For the following 36 patients, one wound was selected from each patient, including 12 wounds on limbs, front torso, and side torso, respectively. The area of wounds was measured by the same attending physician using transparency tracing method, National Institutes of Health (NIH) Image J method, and three dimensional human body scanning system BurnCalc, respectively. The time for getting information of 36 wounds by three methods was recorded by stopwatch. The stability among the testers was evaluated by the intra-class correlation coefficient (ICC). Data were processed with randomized blocks analysis of variance and Bonferroni test. Results: (1) Wound area of patients measured by three physicians using three dimensional human body scanning system BurnCalc was (122±95), (121±95), and (123±96) cm(2,) respectively, and there was no statistically significant difference among them ( F =1.55, P >0.05). The ICC among 3 physicians was 0.999. (2) The wound area of limbs of patients measured by transparency tracing method, NIH Image J method, and three dimensional human body scanning system BurnCalc was (84±50), (76±46), and (84±49) cm(2,) respectively. There was no statistically significant difference in the wound area of limbs of patients measured by transparency tracing method and three dimensional human body scanning system BurnCalc ( P >0.05). The wound area of limbs of patients measured by NIH Image J method was smaller than that measured by transparency tracing method and three dimensional human body scanning system BurnCalc (with P values below 0.05). There was no statistically significant difference in the wound area of front torso of patients measured by transparency tracing method, NIH Image J method, and three dimensional human body scanning system BurnCalc ( F =0.33, P >0.05). The wound area of side torso of patients measured by transparency tracing method, NIH Image J method, and three dimensional human body scanning system BurnCalc was (169±88), (150±80), and (169±86) cm(2,) respectively. There was no statistically significant difference in the wound area of side torso of patients measured by transparency tracing method and three dimensional human body scanning system BurnCalc ( P >0.05). The wound area of side torso of patients measured by NIH Image J method was smaller than that measured by transparency tracing method and three dimensional human body scanning system BurnCalc (with P values below 0.05). (3) The time for getting information of wounds of patients by transparency tracing method, NIH Image J method, and three dimensional human body scanning system BurnCalc was (77±14), (10±3), and (9±3) s, respectively. The time for getting information of wounds of patients by transparency tracing method was longer than that by NIH Image J method and three dimensional human body scanning system BurnCalc (with P values below 0.05). The time for getting information of wounds of patients by three dimensional human body scanning system BurnCalc was close to that by NIH Image J method ( P >0.05). Conclusions: The three dimensional human body scanning system BurnCalc is stable and can accurately evaluate the wound area on limbs and torso of burn patients.

A bacteriophages journey through the human body.

PubMed

Barr, Jeremy J

2017-09-01

The human body is colonized by a diverse collective of microorganisms, including bacteria, fungi, protozoa and viruses. The smallest entity of this microbial conglomerate are the bacterial viruses. Bacteriophages, or phages for short, exert significant selective pressure on their bacterial hosts, undoubtedly influencing the human microbiome and its impact on our health and well-being. Phages colonize all niches of the body, including the skin, oral cavity, lungs, gut, and urinary tract. As such our bodies are frequently and continuously exposed to diverse collections of phages. Despite the prevalence of phages throughout our bodies, the extent of their interactions with human cells, organs, and immune system is still largely unknown. Phages physically interact with our mucosal surfaces, are capable of bypassing epithelial cell layers, disseminate throughout the body and may manipulate our immune system. Here, I establish the novel concept of an "intra-body phageome," which encompasses the collection of phages residing within the classically "sterile" regions of the body. This review will take a phage-centric view of the microbiota, human body, and immune system with the ultimate goal of inspiring a greater appreciation for both the indirect and direct interactions between bacteriophages and their mammalian hosts. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Development of Four Dimensional Human Model that Enables Deformation of Skin, Organs and Blood Vessel System During Body Movement - Visualizing Movements of the Musculoskeletal System.

PubMed

Suzuki, Naoki; Hattori, Asaki; Hashizume, Makoto

2016-01-01

We constructed a four dimensional human model that is able to visualize the structure of a whole human body, including the inner structures, in real-time to allow us to analyze human dynamic changes in the temporal, spatial and quantitative domains. To verify whether our model was generating changes according to real human body dynamics, we measured a participant's skin expansion and compared it to that of the model conducted under the same body movement. We also made a contribution to the field of orthopedics, as we were able to devise a display method that enables the observer to more easily observe the changes made in the complex skeletal muscle system during body movements, which in the past were difficult to visualize.

Human body motion capture from multi-image video sequences

NASA Astrophysics Data System (ADS)

D'Apuzzo, Nicola

2003-01-01

In this paper is presented a method to capture the motion of the human body from multi image video sequences without using markers. The process is composed of five steps: acquisition of video sequences, calibration of the system, surface measurement of the human body for each frame, 3-D surface tracking and tracking of key points. The image acquisition system is currently composed of three synchronized progressive scan CCD cameras and a frame grabber which acquires a sequence of triplet images. Self calibration methods are applied to gain exterior orientation of the cameras, the parameters of internal orientation and the parameters modeling the lens distortion. From the video sequences, two kinds of 3-D information are extracted: a three-dimensional surface measurement of the visible parts of the body for each triplet and 3-D trajectories of points on the body. The approach for surface measurement is based on multi-image matching, using the adaptive least squares method. A full automatic matching process determines a dense set of corresponding points in the triplets. The 3-D coordinates of the matched points are then computed by forward ray intersection using the orientation and calibration data of the cameras. The tracking process is also based on least squares matching techniques. Its basic idea is to track triplets of corresponding points in the three images through the sequence and compute their 3-D trajectories. The spatial correspondences between the three images at the same time and the temporal correspondences between subsequent frames are determined with a least squares matching algorithm. The results of the tracking process are the coordinates of a point in the three images through the sequence, thus the 3-D trajectory is determined by computing the 3-D coordinates of the point at each time step by forward ray intersection. Velocities and accelerations are also computed. The advantage of this tracking process is twofold: it can track natural points, without using markers; and it can track local surfaces on the human body. In the last case, the tracking process is applied to all the points matched in the region of interest. The result can be seen as a vector field of trajectories (position, velocity and acceleration). The last step of the process is the definition of selected key points of the human body. A key point is a 3-D region defined in the vector field of trajectories, whose size can vary and whose position is defined by its center of gravity. The key points are tracked in a simple way: the position at the next time step is established by the mean value of the displacement of all the trajectories inside its region. The tracked key points lead to a final result comparable to the conventional motion capture systems: 3-D trajectories of key points which can be afterwards analyzed and used for animation or medical purposes.

Relationship of insulin, glucose, leptin, IL-6 and TNF-α in human breast milk with infant growth and body composition.

PubMed

Fields, D A; Demerath, E W

2012-08-01

Numerous appetite, growth, obesity-related hormones and inflammatory factors are found in human breast-milk, but there is little evidence on their relationship with infant body composition. OBJECTVIE: The purpose of the present cross-sectional pilot study was to assess the cross-sectional associations of appetite-regulating hormones and growth factors (leptin, insulin and glucose) and inflammatory factors (interleukin 6 (IL-6) and tumor necrosis factor alpha (TNF-α)) in human breast-milk with infant size, adiposity, and lean tissue at 1-month of age in healthy term infants. Human breast-milk was collected from nineteen exclusively breast-feeding mothers using one full breast expression between 8:00 and 10:00 a.m. The milk was then mixed, aliquoted, stored at -80°C and then centrifuged to remove the milk fat, prior to analyses using commercially available immunoassay kits; milk analytes were natural log transformed prior to analysis. Infant body composition was assessed using a Lunar iDXA v11-30.062 scanner (Infant whole body analysis enCore 2007 software, GE, Fairfield, CT). Maternal pre-pregnancy BMI was positively associated with milk leptin concentration (P = 0.0027), and so maternal-BMI-adjusted Spearman correlations were examined between breast-milk analytes and infant growth and body composition variables. As previously reported, greater milk leptin was associated with lower BMIZ (BMI-for-age z-score based on WHO 2006 growth charts; r = -0.54, P = 0.03). Glucose was positively associated with relative weight (r = 0.6, P = 0.01), and both fat and lean mass (0.43-0.44, P < 0.10). Higher concentrations of milk insulin were associated with lower infant weight, relative weight, and lean mass (r = -0.49-0.58, P < 0.06). Higher milk IL-6 was associated with lower relative weight, weight gain, percent fat, and fat mass (r = -0.55-0.70, P < 0.03 for all), while higher TNF-α was associated with lower lean mass (r = -0.58, P = 0.05), but not measures of adiposity. These preliminary data suggest for the first time that in the first months of life, breast-milk concentrations of insulin, glucose, IL-6 and TNF-α, in addition to leptin, may be bioactive and differentially influence the accrual of fat and lean body mass. © 2012 The Authors. Pediatric Obesity © 2012 International Association for the Study of Obesity.

Nonlinearity in the vertical transmissibility of seating: the role of the human body apparent mass and seat dynamic stiffness

NASA Astrophysics Data System (ADS)

Tufano, Saverio; Griffin, Michael J.

2013-01-01

The efficiency of a seat in reducing vibration depends on the characteristics of the vibration, the dynamic characteristics of the seat, and the dynamic characteristics of the person sitting on the seat. However, it is not known whether seat cushions influence the dynamic response of the human body, whether the human body influences the dynamic response of seat cushions, or the relative importance of human body nonlinearity and seat nonlinearity in causing nonlinearity in measures of seat transmissibility. This study was designed to investigate the nonlinearity of the coupled seat and human body systems and to compare the apparent mass of the human body supported on rigid and foam seats. A frequency domain model was used to identify the dynamic parameters of seat foams and investigate their dependence on the subject-sitting weight and hip breadth. With 15 subjects, the force and acceleration at the seat base and acceleration at the subject interface were measured during random vertical vibration excitation (0.25-25 Hz) at each of five vibration magnitudes, (0.25-1.6 ms-2 r.m.s.) with four seating conditions (rigid flat seat and three foam cushions). The measurements are presented in terms of the subject's apparent mass on the rigid and foam seat surfaces, and the transmissibility and dynamic stiffness of each of the foam cushions. Both the human body and the foams showed nonlinear softening behaviour, which resulted in nonlinear cushion transmissibility. The apparent masses of subjects sitting on the rigid seat and on foam cushions were similar, but with an apparent increase in damping when sitting on the foams. The foam dynamic stiffness showed complex correlations with characteristics of the human body, which differed between foams. The nonlinearities in cushion transmissibilities, expressed in terms of changes in resonance frequencies and moduli, were more dependent on human body nonlinearity than on cushion nonlinearity.

“What Women Like”: Influence of Motion and Form on Esthetic Body Perception

PubMed Central

Cazzato, Valentina; Siega, Serena; Urgesi, Cosimo

2012-01-01

Several studies have shown the distinct contribution of motion and form to the esthetic evaluation of female bodies. Here, we investigated how variations of implied motion and body size interact in the esthetic evaluation of female and male bodies in a sample of young healthy women. Participants provided attractiveness, beauty, and liking ratings for the shape and posture of virtual renderings of human bodies with variable body size and implied motion. The esthetic judgments for both shape and posture of human models were influenced by body size and implied motion, with a preference for thinner and more dynamic stimuli. Implied motion, however, attenuated the impact of extreme body size on the esthetic evaluation of body postures, while body size variations did not affect the preference for more dynamic stimuli. Results show that body form and action cues interact in esthetic perception, but the final esthetic appreciation of human bodies is predicted by a mixture of perceptual and affective evaluative components. PMID:22866044

The evolution of body size and shape in the human career

PubMed Central

Grabowski, Mark; Hatala, Kevin G.; Richmond, Brian G.

2016-01-01

Body size is a fundamental biological property of organisms, and documenting body size variation in hominin evolution is an important goal of palaeoanthropology. Estimating body mass appears deceptively simple but is laden with theoretical and pragmatic assumptions about best predictors and the most appropriate reference samples. Modern human training samples with known masses are arguably the ‘best’ for estimating size in early bipedal hominins such as the australopiths and all members of the genus Homo, but it is not clear if they are the most appropriate priors for reconstructing the size of the earliest putative hominins such as Orrorin and Ardipithecus. The trajectory of body size evolution in the early part of the human career is reviewed here and found to be complex and nonlinear. Australopith body size varies enormously across both space and time. The pre-erectus early Homo fossil record from Africa is poor and dominated by relatively small-bodied individuals, implying that the emergence of the genus Homo is probably not linked to an increase in body size or unprecedented increases in size variation. Body size differences alone cannot explain the observed variation in hominin body shape, especially when examined in the context of small fossil hominins and pygmy modern humans. This article is part of the themed issue ‘Major transitions in human evolution’. PMID:27298459

The evolution of body size and shape in the human career.

PubMed

Jungers, William L; Grabowski, Mark; Hatala, Kevin G; Richmond, Brian G

2016-07-05

Body size is a fundamental biological property of organisms, and documenting body size variation in hominin evolution is an important goal of palaeoanthropology. Estimating body mass appears deceptively simple but is laden with theoretical and pragmatic assumptions about best predictors and the most appropriate reference samples. Modern human training samples with known masses are arguably the 'best' for estimating size in early bipedal hominins such as the australopiths and all members of the genus Homo, but it is not clear if they are the most appropriate priors for reconstructing the size of the earliest putative hominins such as Orrorin and Ardipithecus The trajectory of body size evolution in the early part of the human career is reviewed here and found to be complex and nonlinear. Australopith body size varies enormously across both space and time. The pre-erectus early Homo fossil record from Africa is poor and dominated by relatively small-bodied individuals, implying that the emergence of the genus Homo is probably not linked to an increase in body size or unprecedented increases in size variation. Body size differences alone cannot explain the observed variation in hominin body shape, especially when examined in the context of small fossil hominins and pygmy modern humans.This article is part of the themed issue 'Major transitions in human evolution'. © 2016 The Author(s).

Person Recognition System Based on a Combination of Body Images from Visible Light and Thermal Cameras

PubMed Central

Nguyen, Dat Tien; Hong, Hyung Gil; Kim, Ki Wan; Park, Kang Ryoung

2017-01-01

The human body contains identity information that can be used for the person recognition (verification/recognition) problem. In this paper, we propose a person recognition method using the information extracted from body images. Our research is novel in the following three ways compared to previous studies. First, we use the images of human body for recognizing individuals. To overcome the limitations of previous studies on body-based person recognition that use only visible light images for recognition, we use human body images captured by two different kinds of camera, including a visible light camera and a thermal camera. The use of two different kinds of body image helps us to reduce the effects of noise, background, and variation in the appearance of a human body. Second, we apply a state-of-the art method, called convolutional neural network (CNN) among various available methods, for image features extraction in order to overcome the limitations of traditional hand-designed image feature extraction methods. Finally, with the extracted image features from body images, the recognition task is performed by measuring the distance between the input and enrolled samples. The experimental results show that the proposed method is efficient for enhancing recognition accuracy compared to systems that use only visible light or thermal images of the human body. PMID:28300783

Real-time 3D human pose recognition from reconstructed volume via voxel classifiers

NASA Astrophysics Data System (ADS)

Yoo, ByungIn; Choi, Changkyu; Han, Jae-Joon; Lee, Changkyo; Kim, Wonjun; Suh, Sungjoo; Park, Dusik; Kim, Junmo

2014-03-01

This paper presents a human pose recognition method which simultaneously reconstructs a human volume based on ensemble of voxel classifiers from a single depth image in real-time. The human pose recognition is a difficult task since a single depth camera can capture only visible surfaces of a human body. In order to recognize invisible (self-occluded) surfaces of a human body, the proposed algorithm employs voxel classifiers trained with multi-layered synthetic voxels. Specifically, ray-casting onto a volumetric human model generates a synthetic voxel, where voxel consists of a 3D position and ID corresponding to the body part. The synthesized volumetric data which contain both visible and invisible body voxels are utilized to train the voxel classifiers. As a result, the voxel classifiers not only identify the visible voxels but also reconstruct the 3D positions and the IDs of the invisible voxels. The experimental results show improved performance on estimating the human poses due to the capability of inferring the invisible human body voxels. It is expected that the proposed algorithm can be applied to many fields such as telepresence, gaming, virtual fitting, wellness business, and real 3D contents control on real 3D displays.

Phages in the Human Body.

PubMed

Navarro, Ferran; Muniesa, Maite

2017-01-01

Bacteriophages, viruses that infect bacteria, have re-emerged as powerful regulators of bacterial populations in natural ecosystems. Phages invade the human body, just as they do other natural environments, to such an extent that they are the most numerous group in the human virome. This was only revealed in recent metagenomic studies, despite the fact that the presence of phages in the human body was reported decades ago. The influence of the presence of phages in humans has yet to be evaluated; but as in marine environments, a clear role in the regulation of bacterial populations could be envisaged, that might have an impact on human health. Moreover, phages are excellent vehicles of genetic transfer, and they contribute to the evolution of bacterial cells in the human body by spreading and acquiring DNA horizontally. The abundance of phages in the human body does not pass unnoticed and the immune system reacts to them, although it is not clear to what extent. Finally, the presence of phages in human samples, which most of the time is not considered, can influence and bias microbiological and molecular results; and, in view of the evidences, some studies suggest that more attention needs to be paid to their interference.

Human body surface area: a theoretical approach.

PubMed

Wang, Jianfeng; Hihara, Eiji

2004-04-01

Knowledge of the human body surface area has important applications in medical practice, garment design, and other engineering sizing. Therefore, it is not surprising that several expressions correlating body surface area with direct measurements of body mass and length have been reported in the literature. In the present study, based on the assumption that the exterior shape of the human body is the result of convex and concave deformations from a basic cylinder, we derive a theoretical equation minimizing body surface area (BSA) at a fixed volume (V): BSA=(9pi VL)(0.5), where L is the reference length of the body. Assuming a body density value of 1,000 kg.m(-3), the equation becomes BSA=(BM.BH/35.37)(0.5), where BSA is in square meters, BM is the body mass in kilograms, and BH is the body height in meters. BSA values calculated by means of this equation fall within +/-7% of the values obtained by means of the equations available in the literature, in the range of BSA from children to adults. It is also suggested that the above equation, which is obtained by minimizing the outer body surface at a fixed volume, implies a fundamental relation set by the geometrical constraints governing the growth and the development of the human body.

A comprehensive catalogue and classification of human thermal climate indices

NASA Astrophysics Data System (ADS)

de Freitas, C. R.; Grigorieva, E. A.

2015-01-01

The very large number of human thermal climate indices that have been proposed over the past 100 years or so is a manifestation of the perceived importance within the scientific community of the thermal environment and the desire to quantify it. Schemes used differ in approach according to the number of variables taken into account, the rationale employed, the relative sophistication of the underlying body-atmosphere heat exchange theory and the particular design for application. They also vary considerably in type and quality, as well as in several other aspects. Reviews appear in the literature, but they cover a limited number of indices. A project that produces a comprehensive documentation, classification and overall evaluation of the full range of existing human thermal climate indices has never been attempted. This paper deals with documentation and classification. A subsequent report will focus on evaluation. Here a comprehensive register of 162 thermal indices is assembled and a sorting scheme devised that groups them according to eight primary classification classes. It is the first stage in a project to organise and evaluate the full range of all human thermal climate indices. The work, when completed, will make it easier for users to reflect on the merits of all available thermal indices. It will be simpler to locate and compare indices and decide which is most appropriate for a particular application or investigation.

A comprehensive catalogue and classification of human thermal climate indices.

PubMed

de Freitas, C R; Grigorieva, E A

2015-01-01

The very large number of human thermal climate indices that have been proposed over the past 100 years or so is a manifestation of the perceived importance within the scientific community of the thermal environment and the desire to quantify it. Schemes used differ in approach according to the number of variables taken into account, the rationale employed, the relative sophistication of the underlying body-atmosphere heat exchange theory and the particular design for application. They also vary considerably in type and quality, as well as in several other aspects. Reviews appear in the literature, but they cover a limited number of indices. A project that produces a comprehensive documentation, classification and overall evaluation of the full range of existing human thermal climate indices has never been attempted. This paper deals with documentation and classification. A subsequent report will focus on evaluation. Here a comprehensive register of 162 thermal indices is assembled and a sorting scheme devised that groups them according to eight primary classification classes. It is the first stage in a project to organise and evaluate the full range of all human thermal climate indices. The work, when completed, will make it easier for users to reflect on the merits of all available thermal indices. It will be simpler to locate and compare indices and decide which is most appropriate for a particular application or investigation.

[Bullet and shrapnel injuries in the face and neck regions. Current aspects of wound ballistics].

PubMed

Hauer, T; Huschitt, N; Kulla, M; Kneubuehl, B; Willy, C

2011-08-01

A basic understanding of the ballistic behaviour of projectiles or fragments after entering the human body is essential for the head and neck surgeon in the military environment in order to anticipate the diagnostic and therapeutic consequences of this type of injury. Although a large number of factors influence the missile in flight and after penetration of the body, the most important factor is the amount of energy transmitted to the tissue. Long guns (rifles or shotguns) have a much higher muzzle energy compared to handguns, explaining why the remote effects beyond the bullet track play a major role. While most full metal jacket bullets release their energy after 12-20 cm (depending on the calibre), soft point bullets release their energy immediately after entry into the human body. This results in a major difference in extremity wounds, but not so much in injuries with long bullet paths (e.g. diagonal shots). Shrapnel wounds are usually produced with similarly high kinetic energy to those caused by hand- and long guns. However, fragments tend to dissipate the entire amount of energy within the body, which increases the degree of tissue disruption. Of all relevant injuries in the head and neck region, soft tissue injuries make up the largest proportion (60%), while injuries to the face are seen three times more often than injuries to the neck. Concomitant intracranial or spinal injury is seen in 30% of cases. Due to high levels of wound contamination, the infection rate is approximately 15%, often associated with a complicated and/or multiresistant spectrum of germs.

Globalization and the trade in human body parts.

PubMed

Harrison, T

1999-02-01

Since the early 1980s, the number and variety of organ transplantations has increased enormously worldwide. Accompanying this increase has been the emergence of a market for human body parts. This paper argues that, while the trade in human body parts is conditioned by technological advances, it must be understood in the broader context of globalization, specifically the extension and intensification of a capitalist mode of exchange. In this regard, it is argued that the trade in human body parts mirrors the "normal" system of unequal exchanges that mark other forms of trade between the developed and undeveloped regions of the world.

Property rights in human gametes in Australia.

PubMed

White, Vanessa

2013-03-01

It has long been a basic tenet of the common law that there can be no property interest in human bodies or body parts. However, exceptions to the rule have been recognised from the mid-19th century and developed over time. In the early 21st century, there have been interesting developments in the common law of Australia and England, with Australian Supreme Court judges and the English Court of Appeal casting aside existing exceptions, and finding property rights in human body parts, including gametes, by relying instead on a "rational" and "logical" basis to identify property interests in human body parts.

Study of electrical properties of meridian on human body surface

NASA Astrophysics Data System (ADS)

Wang, Feng; Uematsu, Haruyuki; Otani, Nobuo

2007-12-01

This paper presents the study of the subcutaneous electrical impedance on the human body surface. Measurements of the electrical impedance on five adult male subjects were carried out and analyzed for the possible detection of the acupuncture meridian lines of ancient Chinese medicine on the human body. The distribution of electrical impedance measured at 40 points over the volar side of the right upper limb of the subjects. The results show that electrical impedance varies at different locations of the human body surface, and the locations with lower electrical impedance coincide with the locations where the meridian is believed to exist.

Modeling the human body/seat system in a vibration environment.

PubMed

Rosen, Jacob; Arcan, Mircea

2003-04-01

The vibration environment is a common man-made artificial surrounding with which humans have a limited tolerance to cope due to their body dynamics. This research studied the dynamic characteristics of a seated human body/seat system in a vibration environment. The main result is a multi degrees of freedom lumped parameter model that synthesizes two basic dynamics: (i) global human dynamics, the apparent mass phenomenon, including a systematic set of the model parameters for simulating various conditions like body posture, backrest, footrest, muscle tension, and vibration directions, and (ii) the local human dynamics, represented by the human pelvis/vibrating seat contact, using a cushioning interface. The model and its selected parameters successfully described the main effects of the apparent mass phenomenon compared to experimental data documented in the literature. The model provided an analytical tool for human body dynamics research. It also enabled a primary tool for seat and cushioning design. The model was further used to develop design guidelines for a composite cushion using the principle of quasi-uniform body/seat contact force distribution. In terms of evenly distributing the contact forces, the best result for the different materials and cushion geometries simulated in the current study was achieved using a two layer shaped geometry cushion built from three materials. Combining the geometry and the mechanical characteristics of a structure under large deformation into a lumped parameter model enables successful analysis of the human/seat interface system and provides practical results for body protection in dynamic environment.

Quasi-static modeling of human limb for intra-body communications with experiments.

PubMed

Pun, Sio Hang; Gao, Yue Ming; Mak, PengUn; Vai, Mang I; Du, Min

2011-11-01

In recent years, the increasing number of wearable devices on human has been witnessed as a trend. These devices can serve for many purposes: personal entertainment, communication, emergency mission, health care supervision, delivery, etc. Sharing information among the devices scattered across the human body requires a body area network (BAN) and body sensor network (BSN). However, implementation of the BAN/BSN with the conventional wireless technologies cannot give optimal result. It is mainly because the high requirements of light weight, miniature, energy efficiency, security, and less electromagnetic interference greatly limit the resources available for the communication modules. The newly developed intra-body communication (IBC) can alleviate most of the mentioned problems. This technique, which employs the human body as a communication channel, could be an innovative networking method for sensors and devices on the human body. In order to encourage the research and development of the IBC, the authors are favorable to lay a better and more formal theoretical foundation on IBC. They propose a multilayer mathematical model using volume conductor theory for galvanic coupling IBC on a human limb with consideration on the inhomogeneous properties of human tissue. By introducing and checking with quasi-static approximation criteria, Maxwell's equations are decoupled and capacitance effect is included to the governing equation for further improvement. Finally, the accuracy and potential of the model are examined from both in vitro and in vivo experimental results.

Review-Research on the physical training model of human body based on HQ.

PubMed

Junjie, Liu

2016-11-01

Health quotient (HQ) is the newest health culture and concept in the 21st century, and the analysis of the human body sports model is not enough mature at present, what's more, the purpose of this paper is to study the integration of the two subjects the health quotient and the sport model. This paper draws the conclusion that physical training and education in colleges and universities can improve the health quotient, and it will make students possess a more healthy body and mind. Then through a new rigid body model of sports to simulate the human physical exercise. After that this paper has an in-depth study on the dynamic model of the human body movement on the basis of establishing the matrix and equation. The simulation results of the human body bicycle riding and pole throwing show that the human body joint movement simulation can be realized and it has a certain operability as well. By means of such simulated calculation, we can come to a conclusion that the movement of the ankle joint, knee joint and hip joint's motion law and real motion are basically the same. So it further verify the accuracy of the motion model, which lay the foundation of other research movement model, also, the study of the movement model is an important method in the study of human health in the future.

The Biological Effects of Quadripolar Radiofrequency Sequential Application: A Human Experimental Study

PubMed Central

Cornaglia, Antonia Icaro; Faga, Angela; Scevola, Silvia

2014-01-01

Abstract Objective: An experimental study was conducted to assess the effectiveness and safety of an innovative quadripolar variable electrode configuration radiofrequency device with objective measurements in an ex vivo and in vivo human experimental model. Background data: Nonablative radiofrequency applications are well-established anti-ageing procedures for cosmetic skin tightening. Methods: The study was performed in two steps: ex vivo and in vivo assessments. In the ex vivo assessments the radiofrequency applications were performed on human full-thickness skin and subcutaneous tissue specimens harvested during surgery for body contouring. In the in vivo assessments the applications were performed on two volunteer patients scheduled for body contouring surgery at the end of the study. The assessment methods were: clinical examination and medical photography, temperature measurement with thermal imaging scan, and light microscopy histological examination. Results: The ex vivo assessments allowed for identification of the effective safety range for human application. The in vivo assessments allowed for demonstration of the biological effects of sequential radiofrequency applications. After a course of radiofrequency applications, the collagen fibers underwent an immediate heat-induced rearrangement and were partially denaturated and progressively metabolized by the macrophages. An overall thickening and spatial rearrangement was appreciated both in the collagen and elastic fibers, the latter displaying a juvenile reticular pattern. A late onset in the macrophage activation after sequential radiofrequency applications was appreciated. Conclusions: Our data confirm the effectiveness of sequential radiofrequency applications in obtaining attenuation of the skin wrinkles by an overall skin tightening. PMID:25244081

The biological effects of quadripolar radiofrequency sequential application: a human experimental study.

PubMed

Nicoletti, Giovanni; Cornaglia, Antonia Icaro; Faga, Angela; Scevola, Silvia

2014-10-01

An experimental study was conducted to assess the effectiveness and safety of an innovative quadripolar variable electrode configuration radiofrequency device with objective measurements in an ex vivo and in vivo human experimental model. Nonablative radiofrequency applications are well-established anti-ageing procedures for cosmetic skin tightening. The study was performed in two steps: ex vivo and in vivo assessments. In the ex vivo assessments the radiofrequency applications were performed on human full-thickness skin and subcutaneous tissue specimens harvested during surgery for body contouring. In the in vivo assessments the applications were performed on two volunteer patients scheduled for body contouring surgery at the end of the study. The assessment methods were: clinical examination and medical photography, temperature measurement with thermal imaging scan, and light microscopy histological examination. The ex vivo assessments allowed for identification of the effective safety range for human application. The in vivo assessments allowed for demonstration of the biological effects of sequential radiofrequency applications. After a course of radiofrequency applications, the collagen fibers underwent an immediate heat-induced rearrangement and were partially denaturated and progressively metabolized by the macrophages. An overall thickening and spatial rearrangement was appreciated both in the collagen and elastic fibers, the latter displaying a juvenile reticular pattern. A late onset in the macrophage activation after sequential radiofrequency applications was appreciated. Our data confirm the effectiveness of sequential radiofrequency applications in obtaining attenuation of the skin wrinkles by an overall skin tightening.

Bilateral lower limb amputations in a nigerian child following high-voltage electrical burns injury: a case report.

PubMed

Dim, Em; Amanari, Oc; Nottidge, Te; Inyang, Uc; Nwashindi, A

2013-07-01

The human body conducts electricity very well. Direct contact with electric current can be lethal. The passage of electric current through the body is capable of producing a wide spectrum of injuries, including serious damage to the heart, brain, skin and muscles. Naked high-voltage electric cables negligently abandoned in residential, commercial and industrial areas are a recipe for disaster. This is a case report of a 5-year girl child who had bilateral lower limb gangrene following electrical burns injury. She presented with a fourday history of electrical burns injuries of both lower limbs including both gluteal regions, associated with a three-day history of fever, with full thickness burns and sepsis, ultimately leading to bilateral above knee guillotine amputations. High-voltage electric current, bilateral lower limb gangrene, bilateral above knee amputation.

Automated fudicial labeling on human body data

NASA Astrophysics Data System (ADS)

Lewark, Erick A.; Nurre, Joseph H.

1998-03-01

The Cyberware WB4 whole body scanner generates a high- resolution data set of the outer surface of the human body. The acquisition of anthropometric data from this data set is important for the development of custom sizing for the apparel industry. Software for locating anthropometric landmarks from a cloud of more than 200,000 three-dimensional data points, captured from a human subject, is presented. The first phase of identification is to locate externally placed fudicials on the human body using luminance information captured at scan time. The fudicials are then autonomously labeled and categorized according to their general position and anthropometric significance in the scan. Once registration of the landmarks is complete, body measurements may be extracted for apparel sizing.

21 CFR 70.3 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-04-01

..., mineral, or other source and that, when added or applied to a food, drug, or cosmetic or to the human body... intended function of which is to impart color to the human body is a color additive. For the purposes of... of the mixture in coloring foods, drugs, or cosmetics or in coloring the human body. The diluent may...

High School Students' Understanding of the Human Body System

ERIC Educational Resources Information Center

Assaraf, Orit Ben-Zvi; Dodick, Jeff; Tripto, Jaklin

2013-01-01

In this study, 120 tenth-grade students from 8 schools were examined to determine the extent of their ability to perceive the human body as a system after completing the first stage in their biology curriculum--"The human body, emphasizing homeostasis". The students' systems thinking was analyzed according to the STH thinking model, which roughly…

78 FR 23940 - Use of International Standard ISO-10993, “Biological Evaluation of Medical Devices Part 1...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-23

... requests for medical devices that come into direct or indirect contact with the human body in order to... the human body in order to determine the potential toxicity resulting from contact of the component... direct or indirect contact with the human body. This document addresses the following issues: (1) Test...

[A portable impedance meter for monitoring liquid compartments of human body under space flight conditions].

PubMed

Noskov, V B; Nikolaev, D V; Tuĭkin, S A; Kozharinov, V I; Grachev, V A

2007-01-01

A portable two-frequency tetrapolar impedance meter was developed to study the state of liquid compartments of human body under zero-gravity conditions. The portable impedance meter makes it possible to monitor the hydration state of human body under conditions of long-term space flight on board international space station.

Microbial community pattern detection in human body habitats via ensemble clustering framework.

PubMed

Yang, Peng; Su, Xiaoquan; Ou-Yang, Le; Chua, Hon-Nian; Li, Xiao-Li; Ning, Kang

2014-01-01

The human habitat is a host where microbial species evolve, function, and continue to evolve. Elucidating how microbial communities respond to human habitats is a fundamental and critical task, as establishing baselines of human microbiome is essential in understanding its role in human disease and health. Recent studies on healthy human microbiome focus on particular body habitats, assuming that microbiome develop similar structural patterns to perform similar ecosystem function under same environmental conditions. However, current studies usually overlook a complex and interconnected landscape of human microbiome and limit the ability in particular body habitats with learning models of specific criterion. Therefore, these methods could not capture the real-world underlying microbial patterns effectively. To obtain a comprehensive view, we propose a novel ensemble clustering framework to mine the structure of microbial community pattern on large-scale metagenomic data. Particularly, we first build a microbial similarity network via integrating 1920 metagenomic samples from three body habitats of healthy adults. Then a novel symmetric Nonnegative Matrix Factorization (NMF) based ensemble model is proposed and applied onto the network to detect clustering pattern. Extensive experiments are conducted to evaluate the effectiveness of our model on deriving microbial community with respect to body habitat and host gender. From clustering results, we observed that body habitat exhibits a strong bound but non-unique microbial structural pattern. Meanwhile, human microbiome reveals different degree of structural variations over body habitat and host gender. In summary, our ensemble clustering framework could efficiently explore integrated clustering results to accurately identify microbial communities, and provide a comprehensive view for a set of microbial communities. The clustering results indicate that structure of human microbiome is varied systematically across body habitats and host genders. Such trends depict an integrated biography of microbial communities, which offer a new insight towards uncovering pathogenic model of human microbiome.

Microbial community pattern detection in human body habitats via ensemble clustering framework

PubMed Central

2014-01-01

Background The human habitat is a host where microbial species evolve, function, and continue to evolve. Elucidating how microbial communities respond to human habitats is a fundamental and critical task, as establishing baselines of human microbiome is essential in understanding its role in human disease and health. Recent studies on healthy human microbiome focus on particular body habitats, assuming that microbiome develop similar structural patterns to perform similar ecosystem function under same environmental conditions. However, current studies usually overlook a complex and interconnected landscape of human microbiome and limit the ability in particular body habitats with learning models of specific criterion. Therefore, these methods could not capture the real-world underlying microbial patterns effectively. Results To obtain a comprehensive view, we propose a novel ensemble clustering framework to mine the structure of microbial community pattern on large-scale metagenomic data. Particularly, we first build a microbial similarity network via integrating 1920 metagenomic samples from three body habitats of healthy adults. Then a novel symmetric Nonnegative Matrix Factorization (NMF) based ensemble model is proposed and applied onto the network to detect clustering pattern. Extensive experiments are conducted to evaluate the effectiveness of our model on deriving microbial community with respect to body habitat and host gender. From clustering results, we observed that body habitat exhibits a strong bound but non-unique microbial structural pattern. Meanwhile, human microbiome reveals different degree of structural variations over body habitat and host gender. Conclusions In summary, our ensemble clustering framework could efficiently explore integrated clustering results to accurately identify microbial communities, and provide a comprehensive view for a set of microbial communities. The clustering results indicate that structure of human microbiome is varied systematically across body habitats and host genders. Such trends depict an integrated biography of microbial communities, which offer a new insight towards uncovering pathogenic model of human microbiome. PMID:25521415

Revenue Prediction of a Local Event Using the Mathematical Model of Hit Phenomena

NASA Astrophysics Data System (ADS)

Ishii, A.; Matsumoto, T.; Miki, S.

We propose a theoretical approach to investigate human-humaninteraction in the society, which uses a many-body theory that incorporates human-human interaction. We treat advertisement as an external force, and include the word of mouth (WOM) effect as a two-body interaction between humans and the rumor effect as a three-body interaction among humans. The parameters to define the strength of human interactions are assumed to be constant values. The calculated result explained well the two local events ``Mizuki-Shigeru Road in Sakaiminato" and ``the sculpture festival at Tottori" in Japan.

Modeling the relationship between the environment and human experiences.

PubMed

Vink, P; Bazley, C; Jacobs, K

2016-08-12

Within this special issue, different aspects of the environment are studied: aspects that are distant from the human body, close to the body and touching the human body. Consequently, different human senses are involved in these studies as well as the different consequences and effects on the brain and human behaviour. This special issue also highlights many remaining questions about the effects and relationships between environments and human beings and the need for more studies and research. In particular, future studies are needed that address long-term effects and the effects of the combinations of elements which provide comfort or discomfort.

Facilitated early cortical processing of nude human bodies.

PubMed

Alho, Jussi; Salminen, Nelli; Sams, Mikko; Hietanen, Jari K; Nummenmaa, Lauri

2015-07-01

Functional brain imaging has identified specialized neural systems supporting human body perception. Responses to nude vs. clothed bodies within this system are amplified. However, it remains unresolved whether nude and clothed bodies are processed by same cerebral networks or whether processing of nude bodies recruits additional affective and arousal processing areas. We recorded simultaneous MEG and EEG while participants viewed photographs of clothed and nude bodies. Global field power revealed a peak ∼145ms after stimulus onset to both clothed and nude bodies, and ∼205ms exclusively to nude bodies. Nude-body-sensitive responses were centered first (100-200ms) in the extrastriate and fusiform body areas, and subsequently (200-300ms) in affective-motivational areas including insula and anterior cingulate cortex. We conclude that visibility of sexual features facilitates early cortical processing of human bodies, the purpose of which is presumably to trigger sexual behavior and ultimately ensure reproduction. Copyright © 2015 Elsevier B.V. All rights reserved.

Dynamic Human Body Modeling Using a Single RGB Camera.

PubMed

Zhu, Haiyu; Yu, Yao; Zhou, Yu; Du, Sidan

2016-03-18

In this paper, we present a novel automatic pipeline to build personalized parametric models of dynamic people using a single RGB camera. Compared to previous approaches that use monocular RGB images, our system can model a 3D human body automatically and incrementally, taking advantage of human motion. Based on coarse 2D and 3D poses estimated from image sequences, we first perform a kinematic classification of human body parts to refine the poses and obtain reconstructed body parts. Next, a personalized parametric human model is generated by driving a general template to fit the body parts and calculating the non-rigid deformation. Experimental results show that our shape estimation method achieves comparable accuracy with reconstructed models using depth cameras, yet requires neither user interaction nor any dedicated devices, leading to the feasibility of using this method on widely available smart phones.

Dynamic Human Body Modeling Using a Single RGB Camera

PubMed Central

Zhu, Haiyu; Yu, Yao; Zhou, Yu; Du, Sidan

2016-01-01

In this paper, we present a novel automatic pipeline to build personalized parametric models of dynamic people using a single RGB camera. Compared to previous approaches that use monocular RGB images, our system can model a 3D human body automatically and incrementally, taking advantage of human motion. Based on coarse 2D and 3D poses estimated from image sequences, we first perform a kinematic classification of human body parts to refine the poses and obtain reconstructed body parts. Next, a personalized parametric human model is generated by driving a general template to fit the body parts and calculating the non-rigid deformation. Experimental results show that our shape estimation method achieves comparable accuracy with reconstructed models using depth cameras, yet requires neither user interaction nor any dedicated devices, leading to the feasibility of using this method on widely available smart phones. PMID:26999159

Early-life skin microbiota in hospitalized preterm and full-term infants.

PubMed

Younge, Noelle E; Araújo-Pérez, Félix; Brandon, Debra; Seed, Patrick C

2018-05-31

The infant skin microbiota may serve as a reservoir of bacteria that contribute to neonatal infections and stimulate local and systemic immune development. The objectives of our study were to characterize the skin microbiota of preterm and full-term infants during their birth hospitalization and describe its relationship to the microbiota of other body sites and the hospital environment. We conducted a cross-sectional study of 129 infants, including 40 preterm and 89 full-term infants. Samples were collected from five sites: the forehead and posterior auricular scalp (skin upper body); the periumbilical region, inguinal folds, and upper thighs (skin lower body); the oral cavity; the infant's immediate environment; and stool. Staphylococcus, Streptococcus, Enterococcus, and enteric Gram-negative bacteria including Escherichia and Enterobacter dominated the skin microbiota. The preterm infant microbiota at multiple sites had lower alpha diversity and greater enrichment with Staphylococcus and Escherichia than the microbiota of comparable sites in full-term infants. The community structure was highly variable among individuals but differed significantly by body site, postnatal age, and gestational age. Source tracking indicated that each body site both contributed to and received microbiota from other body sites and the hospital environment. The skin microbiota of preterm and full-term infants varied across individuals, by body site, and by the infant's developmental stage. The skin harbored many organisms that are common pathogens in hospitalized infants. Bacterial source tracking suggests that microbiota are commonly exchanged across body sites and the hospital environment as microbial communities mature in infancy.

Scaling a Human Body Finite Element Model with Radial Basis Function Interpolation

DTIC Science & Technology

Human body models are currently used to evaluate the body’s response to a variety of threats to the Soldier. The ability to adjust the size of human...body models is currently limited because of the complex shape changes that are required. Here, a radial basis function interpolation method is used to...morph the shape on an existing finite element mesh. Tools are developed and integrated into the Blender computer graphics software to assist with

Signal transmission in a human body medium-based body sensor network using a Mach-Zehnder electro-optical sensor.

PubMed

Song, Yong; Hao, Qun; Zhang, Kai; Wang, Jingwen; Jin, Xuefeng; Sun, He

2012-11-30

The signal transmission technology based on the human body medium offers significant advantages in Body Sensor Networks (BSNs) used for healthcare and the other related fields. In previous works we have proposed a novel signal transmission method based on the human body medium using a Mach-Zehnder electro-optical (EO) sensor. In this paper, we present a signal transmission system based on the proposed method, which consists of a transmitter, a Mach-Zehnder EO sensor and a corresponding receiving circuit. Meanwhile, in order to verify the frequency response properties and determine the suitable parameters of the developed system, in-vivo measurements have been implemented under conditions of different carrier frequencies, baseband frequencies and signal transmission paths. Results indicate that the proposed system will help to achieve reliable and high speed signal transmission of BSN based on the human body medium.

Signal Transmission in a Human Body Medium-Based Body Sensor Network Using a Mach-Zehnder Electro-Optical Sensor

PubMed Central

Song, Yong; Hao, Qun; Zhang, Kai; Wang, Jingwen; Jin, Xuefeng; Sun, He

2012-01-01

The signal transmission technology based on the human body medium offers significant advantages in Body Sensor Networks (BSNs) used for healthcare and the other related fields. In previous works we have proposed a novel signal transmission method based on the human body medium using a Mach-Zehnder electro-optical (EO) sensor. In this paper, we present a signal transmission system based on the proposed method, which consists of a transmitter, a Mach-Zehnder EO sensor and a corresponding receiving circuit. Meanwhile, in order to verify the frequency response properties and determine the suitable parameters of the developed system, in-vivo measurements have been implemented under conditions of different carrier frequencies, baseband frequencies and signal transmission paths. Results indicate that the proposed system will help to achieve reliable and high speed signal transmission of BSN based on the human body medium. PMID:23443393

Human body fluid proteome analysis

PubMed Central

Hu, Shen; Loo, Joseph A.; Wong, David T.

2010-01-01

The focus of this article is to review the recent advances in proteome analysis of human body fluids, including plasma/serum, urine, cerebrospinal fluid, saliva, bronchoalveolar lavage fluid, synovial fluid, nipple aspirate fluid, tear fluid, and amniotic fluid, as well as its applications to human disease biomarker discovery. We aim to summarize the proteomics technologies currently used for global identification and quantification of body fluid proteins, and elaborate the putative biomarkers discovered for a variety of human diseases through human body fluid proteome (HBFP) analysis. Some critical concerns and perspectives in this emerging field are also discussed. With the advances made in proteomics technologies, the impact of HBFP analysis in the search for clinically relevant disease biomarkers would be realized in the future. PMID:17083142

Human body fluid proteome analysis.

PubMed

Hu, Shen; Loo, Joseph A; Wong, David T

2006-12-01

The focus of this article is to review the recent advances in proteome analysis of human body fluids, including plasma/serum, urine, cerebrospinal fluid, saliva, bronchoalveolar lavage fluid, synovial fluid, nipple aspirate fluid, tear fluid, and amniotic fluid, as well as its applications to human disease biomarker discovery. We aim to summarize the proteomics technologies currently used for global identification and quantification of body fluid proteins, and elaborate the putative biomarkers discovered for a variety of human diseases through human body fluid proteome (HBFP) analysis. Some critical concerns and perspectives in this emerging field are also discussed. With the advances made in proteomics technologies, the impact of HBFP analysis in the search for clinically relevant disease biomarkers would be realized in the future.

[THE LEGAL STATUS OF ELEMENTS AND PRODUCTS OF THE HUMAN BODY: OBJECT OR SUBJECT OF LAW?].

PubMed

De Lameigné, Anaïs Gayte-Papon

2015-07-01

The 2004 Act on bioethics has amended the 1994 Act regarding the donation and the use of elements and products of the human body, medically assisted procreation and prenatal diagnosis. The very purpose of these laws led the legislature not to attempt the summa divisio order distinguishing the object to the person. The analysis of bioethical laws reveals the consecration of the non-commercialization of the human body at the expense of its unavailability. Bioethical laws appear to be catalysts of biological scientific advances releasing the status of the components and the products of the human body while framing it. By limiting scientific opportunities, they prevent human beings from trying to play the sorcerer's apprentice.

Representational Momentum for the Human Body: Awkwardness Matters, Experience Does Not

ERIC Educational Resources Information Center

Wilson, Margaret; Lancaster, Jessy; Emmorey, Karen

2010-01-01

Perception of the human body appears to involve predictive simulations that project forward to track unfolding body-motion events. Here we use representational momentum (RM) to investigate whether implicit knowledge of a learned arbitrary system of body movement such as sign language influences this prediction process, and how this compares to…

Urine trouble: a social history of bedwetting and its regulation.

PubMed

Hurl, Chris

2011-01-01

Bedwetting has confounded the presumed boundaries of the human body, existing in a fluid space, between the normal and pathological, its treatment has demanded the application of a wide array of different technologies, each based on a distinct conception of the relationship between the body and personality, human organs and personal conduct. In tracing the social history of bedwetting and its regulation, this article examines the ontological assumptions underpinning the treatment of bedwetting and how they have changed over the past two centuries. Through the analysis of medical journals, newspaper articles and magazine advertisements, different topologies are identified which redefine the boundaries of the human body and its capacities. From 16th-century naturalism, in which the human body is subordinated to a cosmic totality, to the circumscribed space of 19th-century paediatrics and the expansive circuits of behavioural psychology and modern psychoanalysis, the body has become multiplied, differently enacted through the application of diverse technologies. It was be shown how coordinating the messy and divergent conceptions of the human body has posed an endemic problem for the human sciences, and how the enduring tension between object enactment and subject constitution is an expression of modern "baroque" subjectivity.

Position Estimation Method of Medical Implanted Devices Using Estimation of Propagation Velocity inside Human Body

NASA Astrophysics Data System (ADS)

Kawasaki, Makoto; Kohno, Ryuji

Wireless communication devices in the field of medical implant, such as cardiac pacemakers and capsule endoscopes, have been studied and developed to improve healthcare systems. Especially it is very important to know the range and position of each device because it will contribute to an optimization of the transmission power. We adopt the time-based approach of position estimation using ultra wideband signals. However, the propagation velocity inside the human body differs in each tissue and each frequency. Furthermore, the human body is formed of various tissues with complex structures. For this reason, propagation velocity is different at a different point inside human body and the received signal so distorted through the channel inside human body. In this paper, we apply an adaptive template synthesis method in multipath channel for calculate the propagation time accurately based on the output of the correlator between the transmitter and the receiver. Furthermore, we propose a position estimation method using an estimation of the propagation velocity inside the human body. In addition, we show by computer simulation that the proposal method can perform accurate positioning with a size of medical implanted devices such as a medicine capsule.

Human balance, the evolution of bipedalism and dysequilibrium syndrome.

PubMed

Skoyles, John R

2006-01-01

A new model of the uniqueness, nature and evolution of human bipedality is presented in the context of the etiology of the balance disorder of dysequilibrium syndrome. Human bipedality is biologically novel in several remarkable respects. Humans are (a) obligate, habitual and diverse in their bipedalism, (b) hold their body carriage spinally erect in a multisegmental "antigravity pole", (c) use their forelimbs exclusively for nonlocomotion, (d) support their body weight exclusively by vertical balance and normally never use prehensile holds. Further, human bipedalism is combined with (e) upper body actions that quickly shift the body's center of mass (e.g. tennis serves, piggy-back carrying of children), (f) use transient unstable erect positions (dance, kicking and fighting), (g) body height that makes falls injurious, (h) stiff gait walking, and (i) endurance running. Underlying these novelties, I conjecture, is a species specific human vertical balance faculty. This faculty synchronizes any action with a skeletomuscular adjustment that corrects its potential destabilizing impact upon the projection of the body's center of mass over its foot support. The balance faculty depends upon internal models of the erect vertical body's geometrical relationship (and its deviations) to its support base. Due to the situation that humans are obligate erect terrestrial animals, two frameworks - the body- and gravity-defined frameworks - are in constant alignment in the vertical z-axis. This alignment allows human balance to adapt egocentric body cognitions to detect body deviations from the gravitational vertical. This link between human balance and the processing of geometrical orientation, I propose, accounts for the close link between balance and spatial cognition found in the cerebral cortex. I argue that cortical areas processing the spatial and other cognitions needed to enable vertical balance was an important reason for brain size expansion of Homo erectus. A novel source of evidence for this conjecture is the rare autosomal recessive condition of dysequilibrium syndrome. In dysequilibrium syndrome, individuals fail to learn to walk bipedally (with this not being due to sensory, vestibular nor motor coordination defects). Dysequilibrium syndrome is associated with severe spatial deficits that I conjecture underlie its balance dysfunction. The associated brain defects and gene mutations of dysequilibrium syndrome provide new opportunities to investigate (i) the neurological processes responsible for the human specific balance faculty, and (ii) through gene dating techniques, its evolution.

Preliminary studies: far-field microwave dosimetric measurements of a full-scale model of man.

PubMed

Olsen, R G

1979-12-01

Measurements of microwave heating were made in a full-size, upright human model. The 75-Kg model, composed of electrically simulated muscle, was placed in the far-zone of a standard-gain horn inside an absorber-lined chamber. Pulsed energy at 1.29 GHz was obtained from a military radar transmitter (AN/TPS-1G) and produced radiation at 6-14 mW/cm2 average power density at the location of the model. Microwave heating at the front surface was measured at nine locations on the phantom. Measurements at several depths within the phantom were also made at a central location to gain information on the depth-of-penetration of the microwave energy. Results of the frontal surface measurements and of the penetration study permitted a calculation of the approximate whole-body average specific absorption rate (SAR) when the model's long axis was parallel to the E-field vector. For a normalized power density of 1 mW/cm2 at a frequency of 1.29 GHz, the whole-body average SAR approximated 0.03 W/Kg. This result agrees well with theoretical predictions based on absorption in prolate spheroidal models of man.

Extraction and Classification of Human Gait Features

NASA Astrophysics Data System (ADS)

Ng, Hu; Tan, Wooi-Haw; Tong, Hau-Lee; Abdullah, Junaidi; Komiya, Ryoichi

In this paper, a new approach is proposed for extracting human gait features from a walking human based on the silhouette images. The approach consists of six stages: clearing the background noise of image by morphological opening; measuring of the width and height of the human silhouette; dividing the enhanced human silhouette into six body segments based on anatomical knowledge; applying morphological skeleton to obtain the body skeleton; applying Hough transform to obtain the joint angles from the body segment skeletons; and measuring the distance between the bottom of right leg and left leg from the body segment skeletons. The angles of joints, step-size together with the height and width of the human silhouette are collected and used for gait analysis. The experimental results have demonstrated that the proposed system is feasible and achieved satisfactory results.

Integration methods for thermosensitive gel systems in garments

NASA Astrophysics Data System (ADS)

Reich, A.; Rödel, H.; Stoll, A.; Liske, A.; Zehm, D.

2017-10-01

Humans live and work under severe thermophysiological conditions, which are characterized by extreme temperatures and humidities. Furthermore, additional burdens can arise from physical activities of the human body or the work conditions (resulting in psychological stress) [1]. The thermoregulation of the human body compensates such situations and maintains the core body temperature at 37°C (98,6 °F). The currently used systems for supporting human thermoregulation, such as PCM-equipped surface structures or mobile water-based cooling units have the disadvantage that the running cooling process is neither switchable nor reversible. Another promising possibility for a personal cooling is the use of temperature-dependent superabsorbers (so-called LCST and UCST) in garments, which absorb the human sweat and transmit it to the environment by evaporation. Cooling during evaporation results in heat transfer from the human body.

A portable meter for measuring low frequency currents in the human body.

PubMed

Niple, J C; Daigle, J P; Zaffanella, L E; Sullivan, T; Kavet, R

2004-07-01

A portable meter has been developed for measuring low frequency currents that flow in the human body. Although the present version of the meter was specifically designed to measure 50/60 Hz "contact currents," the principles involved can be used with other low frequency body currents. Contact currents flow when the human body provides a conductive path between objects in the environment with different electrical potentials. The range of currents the meter detects is approximately 0.4-800 microA. This provides measurements of currents from the threshold of human perception (approximately 500 microA(RMS)) down to single microampere levels. The meter has a unique design, which utilizes the human subject's body impedance as the sensing element. Some of the advantages of this approach are high sensitivity, the ability to measure current flow in the majority of the body, and relative insensitivity to the current path connection points. Current measurement accuracy varies with the accuracy of the body impedance (resistance) measurement and different techniques can be used to obtain a desired level of accuracy. Techniques are available to achieve an estimated +/-20% accuracy. Copyright 2004 Wiley-Liss, Inc.

Perception of biological motion from size-invariant body representations.

PubMed

Lappe, Markus; Wittinghofer, Karin; de Lussanet, Marc H E

2015-01-01

The visual recognition of action is one of the socially most important and computationally demanding capacities of the human visual system. It combines visual shape recognition with complex non-rigid motion perception. Action presented as a point-light animation is a striking visual experience for anyone who sees it for the first time. Information about the shape and posture of the human body is sparse in point-light animations, but it is essential for action recognition. In the posturo-temporal filter model of biological motion perception posture information is picked up by visual neurons tuned to the form of the human body before body motion is calculated. We tested whether point-light stimuli are processed through posture recognition of the human body form by using a typical feature of form recognition, namely size invariance. We constructed a point-light stimulus that can only be perceived through a size-invariant mechanism. This stimulus changes rapidly in size from one image to the next. It thus disrupts continuity of early visuo-spatial properties but maintains continuity of the body posture representation. Despite this massive manipulation at the visuo-spatial level, size-changing point-light figures are spontaneously recognized by naive observers, and support discrimination of human body motion.

[Multifaceted body. I. The bodies of medicine].

PubMed

Saraga, M; Bourquin, C; Wykretowicz, H; Stiefel, F

2015-02-11

The human body is the object upon which medicine is acting, but also lived reality, image, symbol, representation and the object of elaboration and theory. All these elements which constitute the body influence the way medicine is treating it. In this series of three articles, we address the human body from various perspectives: medical (1), phenomenological (2), psychosomatic and socio-anthropological (3). This first article discusses four distinct types of representation of the body within medicine, each related to a specific epistemology and shaping a distinct kind of clinical legitimacy: the body-object of anatomy, the body-machine of physiology, the cybernetic body of biology, the statistical body of epidemiology.

Genotyping of human lice suggests multiple emergencies of body lice from local head louse populations.

PubMed

Li, Wenjun; Ortiz, Gabriel; Fournier, Pierre-Edouard; Gimenez, Gregory; Reed, David L; Pittendrigh, Barry; Raoult, Didier

2010-03-23

Genetic analyses of human lice have shown that the current taxonomic classification of head lice (Pediculus humanus capitis) and body lice (Pediculus humanus humanus) does not reflect their phylogenetic organization. Three phylotypes of head lice A, B and C exist but body lice have been observed only in phylotype A. Head and body lice have different behaviours and only the latter have been involved in outbreaks of infectious diseases including epidemic typhus, trench fever and louse borne recurrent fever. Recent studies suggest that body lice arose several times from head louse populations. By introducing a new genotyping technique, sequencing variable intergenic spacers which were selected from louse genomic sequence, we were able to evaluate the genotypic distribution of 207 human lice. Sequence variation of two intergenic spacers, S2 and S5, discriminated the 207 lice into 148 genotypes and sequence variation of another two intergenic spacers, PM1 and PM2, discriminated 174 lice into 77 genotypes. Concatenation of the four intergenic spacers discriminated a panel of 97 lice into 96 genotypes. These intergenic spacer sequence types were relatively specific geographically, and enabled us to identify two clusters in France, one cluster in Central Africa (where a large body louse outbreak has been observed) and one cluster in Russia. Interestingly, head and body lice were not genetically differentiated. We propose a hypothesis for the emergence of body lice, and suggest that humans with both low hygiene and head louse infestations provide an opportunity for head louse variants, able to ingest a larger blood meal (a required characteristic of body lice), to colonize clothing. If this hypothesis is ultimately supported, it would help to explain why poor human hygiene often coincides with outbreaks of body lice. Additionally, if head lice act as a reservoir for body lice, and that any social degradation in human populations may allow the formation of new populations of body lice, then head louse populations are potentially a greater threat to humans than previously assumed.

Genotyping of Human Lice Suggests Multiple Emergences of Body Lice from Local Head Louse Populations

PubMed Central

Li, Wenjun; Ortiz, Gabriel; Fournier, Pierre-Edouard; Gimenez, Gregory; Reed, David L.; Pittendrigh, Barry; Raoult, Didier

2010-01-01

Background Genetic analyses of human lice have shown that the current taxonomic classification of head lice (Pediculus humanus capitis) and body lice (Pediculus humanus humanus) does not reflect their phylogenetic organization. Three phylotypes of head lice A, B and C exist but body lice have been observed only in phylotype A. Head and body lice have different behaviours and only the latter have been involved in outbreaks of infectious diseases including epidemic typhus, trench fever and louse borne recurrent fever. Recent studies suggest that body lice arose several times from head louse populations. Methods and Findings By introducing a new genotyping technique, sequencing variable intergenic spacers which were selected from louse genomic sequence, we were able to evaluate the genotypic distribution of 207 human lice. Sequence variation of two intergenic spacers, S2 and S5, discriminated the 207 lice into 148 genotypes and sequence variation of another two intergenic spacers, PM1 and PM2, discriminated 174 lice into 77 genotypes. Concatenation of the four intergenic spacers discriminated a panel of 97 lice into 96 genotypes. These intergenic spacer sequence types were relatively specific geographically, and enabled us to identify two clusters in France, one cluster in Central Africa (where a large body louse outbreak has been observed) and one cluster in Russia. Interestingly, head and body lice were not genetically differentiated. Conclusions We propose a hypothesis for the emergence of body lice, and suggest that humans with both low hygiene and head louse infestations provide an opportunity for head louse variants, able to ingest a larger blood meal (a required characteristic of body lice), to colonize clothing. If this hypothesis is ultimately supported, it would help to explain why poor human hygiene often coincides with outbreaks of body lice. Additionally, if head lice act as a reservoir for body lice, and that any social degradation in human populations may allow the formation of new populations of body lice, then head louse populations are potentially a greater threat to humans than previously assumed. PMID:20351779

Learning from regeneration research organisms: The circuitous road to scar free wound healing.

PubMed

Erickson, Jami R; Echeverri, Karen

2018-01-15

The skin is the largest organ in the body and plays multiple essential roles ranging from regulating temperature, preventing infection and ultimately defining who we are physically. It is a highly dynamic organ that constantly replaces the outermost cells throughout life. However, when faced with a major injury, human skin cannot restore a significant lesion to its original functionality, instead a reparative scar is formed. In contrast to this, many other species have the unique ability to regenerate full thickness skin without formation of scar tissue. Here we review recent advances in the field that shed light on how the skin cells in regenerative species react to injury to prevent scar formation versus scar forming humans. Copyright © 2017 Elsevier Inc. All rights reserved.

About possibility of temperature trace observing on the human skin using commercially available IR camera

NASA Astrophysics Data System (ADS)

Trofimov, Vyacheslav A.; Trofimov, Vladislav V.; Shestakov, Ivan L.; Blednov, Roman G.

2016-09-01

One of urgent security problems is a detection of objects placed inside the human body. Obviously, for safety reasons one cannot use X-rays for such object detection widely and often. Three years ago, we have demonstrated principal possibility to see a temperature trace, induced by food eating or water drinking, on the human body skin by using a passive THz camera. However, this camera is very expensive. Therefore, for practice it will be very convenient if one can use the IR camera for this purpose. In contrast to passive THz camera using, the IR camera does not allow to see the object under clothing, if an image, produced by this camera, is used directly. Of course, this is a big disadvantage for a security problem solution based on the IR camera using. To overcome this disadvantage we develop novel approach for computer processing of IR camera images. It allows us to increase a temperature resolution of IR camera as well as increasing of human year effective susceptibility. As a consequence of this, a possibility for seeing of a human body temperature changing through clothing appears. We analyze IR images of a person, which drinks water and eats chocolate. We follow a temperature trace on human body skin, caused by changing of temperature inside the human body. Some experiments were made with measurements of a body temperature covered by T-shirt. Shown results are very important for the detection of forbidden objects, cancelled inside the human body, by using non-destructive control without using X-rays.

Relationship between alertness, performance, and body temperature in humans.

PubMed

Wright, Kenneth P; Hull, Joseph T; Czeisler, Charles A

2002-12-01

Body temperature has been reported to influence human performance. Performance is reported to be better when body temperature is high/near its circadian peak and worse when body temperature is low/near its circadian minimum. We assessed whether this relationship between performance and body temperature reflects the regulation of both the internal biological timekeeping system and/or the influence of body temperature on performance independent of circadian phase. Fourteen subjects participated in a forced desynchrony protocol allowing assessment of the relationship between body temperature and performance while controlling for circadian phase and hours awake. Most neurobehavioral measures varied as a function of internal biological time and duration of wakefulness. A number of performance measures were better when body temperature was elevated, including working memory, subjective alertness, visual attention, and the slowest 10% of reaction times. These findings demonstrate that an increased body temperature, associated with and independent of internal biological time, is correlated with improved performance and alertness. These results support the hypothesis that body temperature modulates neurobehavioral function in humans.

Relationship between alertness, performance, and body temperature in humans

NASA Technical Reports Server (NTRS)

Wright, Kenneth P Jr; Hull, Joseph T.; Czeisler, Charles A.

2002-01-01

Body temperature has been reported to influence human performance. Performance is reported to be better when body temperature is high/near its circadian peak and worse when body temperature is low/near its circadian minimum. We assessed whether this relationship between performance and body temperature reflects the regulation of both the internal biological timekeeping system and/or the influence of body temperature on performance independent of circadian phase. Fourteen subjects participated in a forced desynchrony protocol allowing assessment of the relationship between body temperature and performance while controlling for circadian phase and hours awake. Most neurobehavioral measures varied as a function of internal biological time and duration of wakefulness. A number of performance measures were better when body temperature was elevated, including working memory, subjective alertness, visual attention, and the slowest 10% of reaction times. These findings demonstrate that an increased body temperature, associated with and independent of internal biological time, is correlated with improved performance and alertness. These results support the hypothesis that body temperature modulates neurobehavioral function in humans.

Body Composition Changes from Infancy to 4 Years and Associations with Early Childhood Cognition in Preterm and Full-Term Children.

PubMed

Scheurer, Johannah M; Zhang, Lei; Plummer, Erin A; Hultgren, Solveig A; Demerath, Ellen W; Ramel, Sara E

2018-06-13

Infants born prematurely are at risk for neurodevelopmental complications. Early growth is associated with improved later cognition. The relationship of early proportionality and body composition with later cognition is not well established. To assess differences in fat-free mass and adiposity (fat mass, percent body fat) changes in preterm and full-term infants through preschool age and examine associations with early childhood cognition. This is a prospective, observational study in an appropriate for gestational age cohort of 71 patients (20 preterm and 51 full-term) from infancy through preschool age. Anthropometric and body composition measurements via air displacement plethysmography were obtained during infancy at term and 3-4 months (preterm corrected ages), and at 4 years. Cognitive testing occurred at 4 years. Associations of body composition changes between visits with cognitive function were tested using linear regression. In the preterm group, higher term to 4-month corrected age percent body fat gains were associated with lower working memory performance (p = 0.01), and higher 4-month corrected age to 4-year fat-free mass gains were associated with higher full-scale IQ (p = 0.03) and speed of processing performance (p ≤ 0.02). In the full-term group, higher 4-month to 4-year fat mass gains were associated with lower full-scale IQ (p = 0.03). Body composition gains during different time periods are associated with varying areas of cognitive function. These findings may inform interventions aimed at optimal growth. © 2018 S. Karger AG, Basel.

Observation of temperature trace, induced by changing of temperature inside the human body, on the human body skin using commercially available IR camera

NASA Astrophysics Data System (ADS)

Trofimov, Vyacheslav A.; Trofimov, Vladislav V.

2015-05-01

As it is well-known, application of the passive THz camera for the security problems is very promising way. It allows seeing concealed object without contact with a person and this camera is non-dangerous for a person. In previous papers, we demonstrate new possibility of the passive THz camera using for a temperature difference observing on the human skin if this difference is caused by different temperatures inside the body. For proof of validity of our statement we make the similar physical experiment using the IR camera. We show a possibility of temperature trace on human body skin, caused by changing of temperature inside the human body due to water drinking. We use as a computer code that is available for treatment of images captured by commercially available IR camera, manufactured by Flir Corp., as well as our developed computer code for computer processing of these images. Using both codes we demonstrate clearly changing of human body skin temperature induced by water drinking. Shown phenomena are very important for the detection of forbidden samples and substances concealed inside the human body using non-destructive control without X-rays using. Early we have demonstrated such possibility using THz radiation. Carried out experiments can be used for counter-terrorism problem solving. We developed original filters for computer processing of images captured by IR cameras. Their applications for computer processing of images results in a temperature resolution enhancing of cameras.

Human body shape index based on an experimentally derived model of human growth.

PubMed

Lebiedowska, Maria K; Alter, Katharine E; Stanhope, Steven J

2008-01-01

To test the assumption of geometrically similar growth by developing experimentally derived models of human body growth during the age interval of 5 to 18 years; to use these derived growth models to establish a new human body shape index (HBSI) based on natural age-related changes in human body shape (HBS); and to compare various metrics of relative body weight (body mass index [BMI], ponderal index [PI], and HBSI) in a sample of 5- to 18-year-old children. Nondisabled Polish children (n = 847) participated in this descriptive study. To model growth, the best fit between body height (H) and body mass (M) was calculated for each sex using the allometric equation M = m(i) H(chi). HBSI was calculated separately for girls and boys, using sex-specific values for chi and a general HBSI from combined data. The customary BMI and PI were calculated and compared with HBSI values. The models of growth were M = 13.11H(2.84) (R2 = 0.90) for girls and M = 13.64H(2.68) (R2 = 0.91) for boys. HBSI values contained less inherent variability and were less influenced by growth (age and height) compared with BMI and PI. Age-related growth during childhood is sex-specific and not geometrically similar. Therefore, indices of HBS formulated from experimentally derived models of human growth are superior to customary geometric similarity-based indices for characterizing HBS in children during the formative growth years.

Electric Shock and the Human Body.

ERIC Educational Resources Information Center

Brown, Colin

1986-01-01

Discusses electricity's documented effects on the human body, including both the dangers to human health and the medical application of electrical stimulation to heart problems. Discusses the teaching of such physics topics to potential medical students. (TW)

Biodynamics of deformable human body motion

NASA Technical Reports Server (NTRS)

Strauss, A. M.; Huston, R. L.

1976-01-01

The objective is to construct a framework wherein the various models of human biomaterials fit in order to describe the biodynamic response of the human body. The behavior of the human body in various situations, from low frequency, low amplitude vibrations to impact loadings in automobile and aircraft crashes, is very complicated with respect to all aspects of the problem: materials, geometry and dynamics. The materials problem is the primary concern, but the materials problem is intimately connected with geometry and dynamics.

Benefits and applications of interdisciplinary digital tools for environmental meta-reviews and analyses

NASA Astrophysics Data System (ADS)

Grubert, Emily; Siders, Anne

2016-09-01

Digitally-aided reviews of large bodies of text-based information, such as academic literature, are growing in capability but are not yet common in environmental fields. Environmental sciences and studies can benefit from application of digital tools to create comprehensive, replicable, interdisciplinary reviews that provide rapid, up-to-date, and policy-relevant reports of existing work. This work reviews the potential for applications of computational text mining and analysis tools originating in the humanities to environmental science and policy questions. Two process-oriented case studies of digitally-aided environmental literature reviews and meta-analyses illustrate potential benefits and limitations. A medium-sized, medium-resolution review (∼8000 journal abstracts and titles) focuses on topic modeling as a rapid way to identify thematic changes over time. A small, high-resolution review (∼300 full text journal articles) combines collocation and network analysis with manual coding to synthesize and question empirical field work. We note that even small digitally-aided analyses are close to the upper limit of what can be done manually. Established computational methods developed in humanities disciplines and refined by humanities and social science scholars to interrogate large bodies of textual data are applicable and useful in environmental sciences but have not yet been widely applied. Two case studies provide evidence that digital tools can enhance insight. Two major conclusions emerge. First, digital tools enable scholars to engage large literatures rapidly and, in some cases, more comprehensively than is possible manually. Digital tools can confirm manually identified patterns or identify additional patterns visible only at a large scale. Second, digital tools allow for more replicable and transparent conclusions to be drawn from literature reviews and meta-analyses. The methodological subfields of digital humanities and computational social sciences will likely continue to create innovative tools for analyzing large bodies of text, providing opportunities for interdisciplinary collaboration with the environmental fields.

The "spare parts person"? Conceptions of the human body and their implications for public attitudes towards organ donation and organ sale.

PubMed

Schweda, Mark; Schicktanz, Silke

2009-02-18

The increasing debate on financial incentives for organ donation raises concerns about a "commodification of the human body". Philosophical-ethical stances on this development depend on assumptions concerning the body and how people think about it. In our qualitative empirical study we analyze public attitudes towards organ donation in their specific relation to conceptions of the human body in four European countries (Cyprus, Germany, the Netherlands and Sweden). This approach aims at a more context-sensitive picture of what "commodification of the body" can mean in concrete clinical decisions concerning organ donation. We find that moral intuitions concerning organ donation are rooted in various conceptions of the human body and its relation to the self: a) the body as a mechanical object owned by the self, b) the body as a part of a higher order embodying the self, and c) the body as a hierarchy of organs constitutive of the self. The language of commodification is much too simple to capture what is at stake in everyday life intuitions about organ donation and organ sale. We discuss how the plurality of underlying body-self conceptions can be taken into account in the ethical debate, pointing out consequences for an anthropologically informed approach and for a liberal perspective.

Tensor body: real-time reconstruction of the human body and avatar synthesis from RGB-D.

PubMed

Barmpoutis, Angelos

2013-10-01

Real-time 3-D reconstruction of the human body has many applications in anthropometry, telecommunications, gaming, fashion, and other areas of human-computer interaction. In this paper, a novel framework is presented for reconstructing the 3-D model of the human body from a sequence of RGB-D frames. The reconstruction is performed in real time while the human subject moves arbitrarily in front of the camera. The method employs a novel parameterization of cylindrical-type objects using Cartesian tensor and b-spline bases along the radial and longitudinal dimension respectively. The proposed model, dubbed tensor body, is fitted to the input data using a multistep framework that involves segmentation of the different body regions, robust filtering of the data via a dynamic histogram, and energy-based optimization with positive-definite constraints. A Riemannian metric on the space of positive-definite tensor splines is analytically defined and employed in this framework. The efficacy of the presented methods is demonstrated in several real-data experiments using the Microsoft Kinect sensor.

Abstracting Dance: Detaching Ourselves from the Habitual Perception of the Moving Body.

PubMed

Aviv, Vered

2017-01-01

This work explores to what extent the notion of abstraction in dance is valid and what it entails. Unlike abstraction in the fine arts that aims for a certain independence from representation of the external world through the use of non-figurative elements, dance is realized by a highly familiar object - the human body. In fact, we are all experts in recognizing the human body. For instance, we can mentally reconstruct its motion from minimal information (e.g., via a "dot display"), predict body trajectory during movement and identify emotional expressions of the body. Nonetheless, despite the presence of a human dancer on stage and our extreme familiarity with the human body, the process of abstraction is applicable also to dance. Abstract dance removes itself from familiar daily movements, violates the observer's predictions about future movements and detaches itself from narratives. In so doing, abstract dance exposes the observer to perceptions of unfamiliar situations, thus paving the way to new interpretations of human motion and hence to perceiving ourselves differently in both the physical and emotional domains.

Abstracting Dance: Detaching Ourselves from the Habitual Perception of the Moving Body

PubMed Central

Aviv, Vered

2017-01-01

This work explores to what extent the notion of abstraction in dance is valid and what it entails. Unlike abstraction in the fine arts that aims for a certain independence from representation of the external world through the use of non-figurative elements, dance is realized by a highly familiar object – the human body. In fact, we are all experts in recognizing the human body. For instance, we can mentally reconstruct its motion from minimal information (e.g., via a “dot display”), predict body trajectory during movement and identify emotional expressions of the body. Nonetheless, despite the presence of a human dancer on stage and our extreme familiarity with the human body, the process of abstraction is applicable also to dance. Abstract dance removes itself from familiar daily movements, violates the observer’s predictions about future movements and detaches itself from narratives. In so doing, abstract dance exposes the observer to perceptions of unfamiliar situations, thus paving the way to new interpretations of human motion and hence to perceiving ourselves differently in both the physical and emotional domains. PMID:28559871

Very low birth weight infants who are fed human milk have decreased body fat as assessed by air displacement plethysmography

USDA-ARS?s Scientific Manuscript database

Methods to evaluate body composition in infants have recently been enhanced. There are few data regarding body composition in very low birth weight (VLBW) infants. Our objective was to evaluate body composition in VLBW infants consuming human milk or formula using novel techniques. Using air-displac...

Estimation of the whole-body averaged SAR of grounded human models for plane wave exposure at respective resonance frequencies.

PubMed

Hirata, Akimasa; Yanase, Kazuya; Laakso, Ilkka; Chan, Kwok Hung; Fujiwara, Osamu; Nagaoka, Tomoaki; Watanabe, Soichi; Conil, Emmanuelle; Wiart, Joe

2012-12-21

According to the international guidelines, the whole-body averaged specific absorption rate (WBA-SAR) is used as a metric of basic restriction for radio-frequency whole-body exposure. It is well known that the WBA-SAR largely depends on the frequency of the incident wave for a given incident power density. The frequency at which the WBA-SAR becomes maximal is called the 'resonance frequency'. Our previous study proposed a scheme for estimating the WBA-SAR at this resonance frequency based on an analogy between the power absorption characteristic of human models in free space and that of a dipole antenna. However, a scheme for estimating the WBA-SAR in a grounded human has not been discussed sufficiently, even though the WBA-SAR in a grounded human is larger than that in an ungrounded human. In this study, with the use of the finite-difference time-domain method, the grounded condition is confirmed to be the worst-case exposure for human body models in a standing posture. Then, WBA-SARs in grounded human models are calculated at their respective resonant frequencies. A formula for estimating the WBA-SAR of a human standing on the ground is proposed based on an analogy with a quarter-wavelength monopole antenna. First, homogenized human body models are shown to provide the conservative WBA-SAR as compared with anatomically based models. Based on the formula proposed here, the WBA-SARs in grounded human models are approximately 10% larger than those in free space. The variability of the WBA-SAR was shown to be ±30% even for humans of the same age, which is caused by the body shape.

16 CFR 1500.90 - Procedures and requirements for exclusions from lead limits under section 101(b) of the Consumer...

Code of Federal Regulations, 2010 CFR

2010-01-01

... inaccessible to a child or prevent the absorption of any lead in the human body through normal and reasonably... in the absorption of any lead into the human body, taking into account normal and reasonably... sought, will not result in the absorption of any lead into the human body, nor have any other adverse...

16 CFR 1500.90 - Procedures and requirements for exclusions from lead limits under section 101(b) of the Consumer...

Code of Federal Regulations, 2011 CFR

2011-01-01

... inaccessible to a child or prevent the absorption of any lead in the human body through normal and reasonably... in the absorption of any lead into the human body, taking into account normal and reasonably... sought, will not result in the absorption of any lead into the human body, nor have any other adverse...

Inversion Effects in the Perception of the Moving Human Form: A Comparison of Adolescents with Autism Spectrum Disorder and Typically Developing Adolescents

ERIC Educational Resources Information Center

Cleary, Laura; Looney, Kathy; Brady, Nuala; Fitzgerald, Michael

2014-01-01

The "body inversion effect" refers to superior recognition of upright than inverted images of the human body and indicates typical configural processing. Previous research by Reed et al. using static images of the human body shows that people with autism fail to demonstrate this effect. Using a novel task in which adults, adolescents…

[Multifaceted body. 3. The contextualised body].

PubMed

Bourquin, C; Wykretowicz, H; Saraga, M; Stiefel, F

2015-02-11

The human body is the object upon which medicine is acting, but also lived reality, image, symbol, representation and the object of elaboration and theory. All these elements which constitute the body influence the way medicine is treating it. In this series of three articles, we address the human body from various perspectives: medical (1), phenomenological (2), psychosomatic and socio-anthropological (3). This third and last article focuses on the psychosomatic and socio-anthropological facets of the body and their contribution to its understanding.

The properties of human body phantoms used in calculations of electromagnetic fields exposure by wireless communication handsets or hand-operated industrial devices.

PubMed

Zradziński, Patryk

2013-06-01

According to international guidelines, the assessment of biophysical effects of exposure to electromagnetic fields (EMF) generated by hand-operated sources needs the evaluation of induced electric field (E(in)) or specific energy absorption rate (SAR) caused by EMF inside a worker's body and is usually done by the numerical simulations with different protocols applied to these two exposure cases. The crucial element of these simulations is the numerical phantom of the human body. Procedures of E(in) and SAR evaluation due to compliance analysis with exposure limits have been defined in Institute of Electrical and Electronics Engineers standards and International Commission on Non-Ionizing Radiation Protection guidelines, but a detailed specification of human body phantoms has not been described. An analysis of the properties of over 30 human body numerical phantoms was performed which has been used in recently published investigations related to the assessment of EMF exposure by various sources. The differences in applicability of these phantoms in the evaluation of E(in) and SAR while operating industrial devices and SAR while using mobile communication handsets are discussed. The whole human body numerical phantom dimensions, posture, spatial resolution and electric contact with the ground constitute the key parameters in modeling the exposure related to industrial devices, while modeling the exposure from mobile communication handsets, which needs only to represent the exposed part of the human body nearest to the handset, mainly depends on spatial resolution of the phantom. The specification and standardization of these parameters of numerical human body phantoms are key requirements to achieve comparable and reliable results from numerical simulations carried out for compliance analysis against exposure limits or within the exposure assessment in EMF-related epidemiological studies.

Segmenting human from photo images based on a coarse-to-fine scheme.

PubMed

Lu, Huchuan; Fang, Guoliang; Shao, Xinqing; Li, Xuelong

2012-06-01

Human segmentation in photo images is a challenging and important problem that finds numerous applications ranging from album making and photo classification to image retrieval. Previous works on human segmentation usually demand a time-consuming training phase for complex shape-matching processes. In this paper, we propose a straightforward framework to automatically recover human bodies from color photos. Employing a coarse-to-fine strategy, we first detect a coarse torso (CT) using the multicue CT detection algorithm and then extract the accurate region of the upper body. Then, an iterative multiple oblique histogram algorithm is presented to accurately recover the lower body based on human kinematics. The performance of our algorithm is evaluated on our own data set (contains 197 images with human body region ground truth data), VOC 2006, and the 2010 data set. Experimental results demonstrate the merits of the proposed method in segmenting a person with various poses.

Modern medicine and the "uncertain body": from corporeality to hyperreality?

PubMed

Williams, S J

1997-10-01

This paper (re)considers the role of medical technology at three interrelated levels: first, the extent to which medical technology renders our bodies increasingly "uncertain" at the turn of the century; second, the analytical purchase which the notion of the (medical) cyborg provides regarding contemporary forms of human embodiment; and finally, at a broader level, the issues this raises in relation to a (late) modernist or postmodernist reading of contemporary medical practice. Key themes here include the plastic body, the bionic body, communal/interchangeable bodies, (genetically) engineered/ chosen bodies, and virtual bodies. The paper concludes with a critical appraisal of these themes and issues, arguing for a late modernist position on medical technology as both a positive and negative rationalising force, and a "life political agenda" in which the "all-too-human" quality of human nature is seen as inviolable.

Evidence of a chimpanzee-sized ancestor of humans but a gibbon-sized ancestor of apes.

PubMed

Grabowski, Mark; Jungers, William L

2017-10-12

Body mass directly affects how an animal relates to its environment and has a wide range of biological implications. However, little is known about the mass of the last common ancestor (LCA) of humans and chimpanzees, hominids (great apes and humans), or hominoids (all apes and humans), which is needed to evaluate numerous paleobiological hypotheses at and prior to the root of our lineage. Here we use phylogenetic comparative methods and data from primates including humans, fossil hominins, and a wide sample of fossil primates including Miocene apes from Africa, Europe, and Asia to test alternative hypotheses of body mass evolution. Our results suggest, contrary to previous suggestions, that the LCA of all hominoids lived in an environment that favored a gibbon-like size, but a series of selective regime shifts, possibly due to resource availability, led to a decrease and then increase in body mass in early hominins from a chimpanzee-sized LCA.The pattern of body size evolution in hominids can provide insight into historical human ecology. Here, Grabowski and Jungers use comparative phylogenetic analysis to reconstruct the likely size of the ancestor of humans and chimpanzees and the evolutionary history of selection on body size in primates.

A Bayesian Framework for Human Body Pose Tracking from Depth Image Sequences

PubMed Central

Zhu, Youding; Fujimura, Kikuo

2010-01-01

This paper addresses the problem of accurate and robust tracking of 3D human body pose from depth image sequences. Recovering the large number of degrees of freedom in human body movements from a depth image sequence is challenging due to the need to resolve the depth ambiguity caused by self-occlusions and the difficulty to recover from tracking failure. Human body poses could be estimated through model fitting using dense correspondences between depth data and an articulated human model (local optimization method). Although it usually achieves a high accuracy due to dense correspondences, it may fail to recover from tracking failure. Alternately, human pose may be reconstructed by detecting and tracking human body anatomical landmarks (key-points) based on low-level depth image analysis. While this method (key-point based method) is robust and recovers from tracking failure, its pose estimation accuracy depends solely on image-based localization accuracy of key-points. To address these limitations, we present a flexible Bayesian framework for integrating pose estimation results obtained by methods based on key-points and local optimization. Experimental results are shown and performance comparison is presented to demonstrate the effectiveness of the proposed approach. PMID:22399933

Effect of the environmental stimuli upon the human body in winter outdoor thermal environment.

PubMed

Kurazumi, Yoshihito; Kondo, Emi; Ishii, Jin; Sakoi, Tomonori; Fukagawa, Kenta; Bolashikov, Zhecho Dimitrov; Tsuchikawa, Tadahiro; Matsubara, Naoki; Horikoshi, Tetsumi

2013-01-01

In order to manage the outdoor thermal environment with regard to human health and the environmental impact of waste heat, quantitative evaluations are indispensable. It is necessary to use a thermal environment evaluation index. The purpose of this paper is to clarify the relationship between the psychological thermal responses of the human body and winter outdoor thermal environment variables. Subjective experiments were conducted in the winter outdoor environment. Environmental factors and human psychological responses were measured. The relationship between the psychological thermal responses of the human body and the outdoor thermal environment index ETFe (enhanced conduction-corrected modified effective temperature) in winter was shown. The variables which influence the thermal sensation vote of the human body are air temperature, long-wave thermal radiation and short-wave solar radiation. The variables that influence the thermal comfort vote of the human body are air temperature, humidity, short-wave solar radiation, long-wave thermal radiation, and heat conduction. Short-wave solar radiation, and heat conduction are among the winter outdoor thermal environment variables that affect psychological responses to heat. The use of thermal environment evaluation indices that comprise short-wave solar radiation and heat conduction in winter outdoor spaces is a valid approach.

Body symmetry and asymmetry in early Greek anatomical reasoning.

PubMed

Crivellato, Enrico; Ribatti, Domenico

2008-05-01

This historical note focuses on some of the earliest reports of human anatomy found in Greek medical literature. These passages testify the initial steps taken by Greek scientists in building a theoretical model of the human body. In these excerpts, one finds erroneous anatomical descriptions, which shed light on the epistemological approach used by these intellectual pioneers. Because of the lack of systematic dissection, it appears that early Greek anatomists developed a somewhat stylized idea of the human body that used a certain degree of symmetry. Overcoming the concept of a strict left-right bilateral parallelism in human body architecture was a challenging intellectual task that required prolonged observation of dissected corpses. (c) 2008 Wiley-Liss, Inc.

Expression, purification and characterization of a full-length recombinant HIV-1 Vpu from inclusion bodies.

PubMed

Njengele, Zikhona; Kleynhans, Ronel; Sayed, Yasien; Mosebi, Salerwe

2016-12-01

Vpu is one of four accessory proteins encoded by human immunodeficiency virus type I (HIV-1). Vpu modulates the expression of several cellular restriction factors within the HIV-1 infected cell including CD4, CD74, the bone marrow stromal antigen 2 (BST-2) and NK-T-and-B antigen. The interaction of HIV-1 Vpu with these proteins interferes with the innate immune response directed against HIV-1; thereby promoting viral persistence. The involvement of HIV-1 Vpu in manipulating the cellular environment in ways that favor viral replication makes it an attractive target for anti-HIV drug intervention. This paper describes the over-expression and purification of a soluble HIV-1 Vpu from inclusion bodies by ion-exchange chromatography, allowing production of 6 mg of highly purified protein (>95% purity) per 10 mg of pelleted cells obtained from 1 L of bacterial culture. Far-UV circular dichroism showed that the recombinant protein is folded and retained its secondary structure. Moreover, using ELISA, known HIV-1 Vpu binding partners, BST-2 and CD74, showed that the refolded purified protein is functional or at least assumes a conformation that is capable of binding these putative binding partners. To our knowledge, this is the first report of the purification and successful solubilization of full-length, wild-type HIV-1 Vpu from inclusion bodies in Escherichia coli. Copyright © 2016 Elsevier Inc. All rights reserved.

About possibility of temperature trace observing on a human skin through clothes by using computer processing of IR image

NASA Astrophysics Data System (ADS)

Trofimov, Vyacheslav A.; Trofimov, Vladislav V.; Shestakov, Ivan L.; Blednov, Roman G.

2017-05-01

One of urgent security problems is a detection of objects placed inside the human body. Obviously, for safety reasons one cannot use X-rays for such object detection widely and often. For this purpose, we propose to use THz camera and IR camera. Below we continue a possibility of IR camera using for a detection of temperature trace on a human body. In contrast to passive THz camera using, the IR camera does not allow to see very pronounced the object under clothing. Of course, this is a big disadvantage for a security problem solution based on the IR camera using. To find possible ways for this disadvantage overcoming we make some experiments with IR camera, produced by FLIR Company and develop novel approach for computer processing of images captured by IR camera. It allows us to increase a temperature resolution of IR camera as well as human year effective susceptibility enhancing. As a consequence of this, a possibility for seeing of a human body temperature changing through clothing appears. We analyze IR images of a person, which drinks water and eats chocolate. We follow a temperature trace on human body skin, caused by changing of temperature inside the human body. Some experiments are made with observing of temperature trace from objects placed behind think overall. Demonstrated results are very important for the detection of forbidden objects, concealed inside the human body, by using non-destructive control without using X-rays.

Comparative assessment of endocrine modulators with oestrogenic activity: I. Definition of a hygiene-based margin of safety (HBMOS) for xeno-oestrogens against the background of European developments.

PubMed

Bolt, H M; Janning, P; Michna, H; Degen, G H

2001-01-01

A novel concept - the hygiene-based margin of safety (HBMOS) - is suggested for the assessment of the impact of potential endocrine modulators. It integrates exposure scenarios and potency data for industrial chemicals and naturally occurring dietary compounds with oestrogenic activity. An HBMOS is defined as a quotient of estimated daily intakes weighted by the relative in vivo potencies of these compounds. The Existing Chemicals Programme of the European Union provides Human and Environmental Risk Assessments of Existing Chemicals which include human exposure scenarios. Such exposure scenarios, along with potency estimates for endocrine activities, may provide a basis for a quantitative comparison of the potential endocrine-modulating effects of industrial chemicals with endocrine modulators as natural constituents of human diet. Natural phyto-oestrogens exhibit oestrogenic activity in vitro and in vivo. Important phyto-oestrogens for humans are isoflavones (daidzein, genistein) and lignans, with the highest quantities found in soybeans and flaxseed, respectively. Daily isoflavone exposures calculated for infants on soy-based formulae were in the ranges of 4.5-8 mg/kg body wt.; estimates for adults range up to 1 mg/kg body wt. The Senate Commission on the Evaluation of Food Safety (SKLM) of the Deutsche Forschungsgemeinschaft has also indicated a wide range of dietary exposures. For matters of risk assessment, the SKLM has based recommendations on dietary exposure scenarios, implying a daily intake of phyto-oestrogens in the order of 1 mg/kg body wt. On the basis of information compiled within the Existing Chemicals Programme of the EU, it appears that a daily human exposure to nonylphenol of 2 microg/kg body wt. may be a worst-case assumption, but which is based on valid scenarios. The intake of octylphenol is much lower, due to a different use pattern and applications, and may be neglected. Data from migration studies led to estimations of the daily human uptake of bisphenol A of maximally 1 microg/kg body wt. On the basis of comparative data from uterotrophic assays in rats, with three consecutive days of oral applications involved, and taking the natural phyto-oestrogen daidzein as reference (= 1), relative uterotrophic activities in DA/Han rats follow the sequence: daidzein = 1; bisphenol A = 1; p-tertoctylphenol = 2; o, p'-DDT = 4; ethinyl oestradiol = 40,000. The derived values from exposure scenarios, as well as these relative potency values and bridging assumptions, led to calculations of HBMOS as a quantitative comparison of potential endocrine-modulating effects of industrial chemicals with those of natural constituents of human diet. HBMOS estimates for nonylphenol ranged between 250 and 500, dependent on bridging assumptions, and around 1000 for bisphenol A. The derivations of HBMOS were in full support of the conclusions reached by the SKLM of the Deutsche Forschungsgemeinschaft. The estimated HBMOS values for the industrial chemicals (nonylphenol, bisphenol A) appear sufficiently high to ensure the absence of a practical risk to human health under the present exposure conditions.

The Role of Age on Multisensory Bodily Experience: An Experimental Study with a Virtual Reality Full-Body Illusion.

PubMed

Serino, Silvia; Scarpina, Federica; Dakanalis, Antonios; Keizer, Anouk; Pedroli, Elisa; Castelnuovo, Gianluca; Chirico, Alice; Catallo, Valentina; di Lernia, Daniele; Riva, Giuseppe

2018-05-01

A growing body of evidence demonstrated that it is feasible to induce ownership over an artificial body to alter bodily experience. However, several uncharted aspects about full-body illusion applications need to be tackled before a complete exploitation of these methods in clinical practice. This work is devoted to explore possible individual age-related differences in shaping changes in body representations induced with a full-body illusion. A total of 40 women were divided into two different age groups according to the median of the variable age. Participants estimated the width of three different body parts (i.e., shoulders, abdomen, and hips) before the entire illusion was induced (baseline), and after the synchronous and the asynchronous conditions. Results revealed that 26-to-55-year-old participants were more resistant to changes induced by the bodily illusion, whereas 19-to-25-year-old participants underestimated their bodies after both conditions. The findings were discussed in terms of the literature exploring age differences in responses to bodily illusion, which could suggest a Bayesian mechanism underlying these individual differences.

Investigation of the transmission of fore and aft vibration through the human body.

PubMed

Demić, Miroslav; Lukić, Jovanka

2009-07-01

Understanding the behavior of human body under the influence of vibration is of great importance for the optimal motor vehicle system design. Therefore, great efforts are being done in order to discover as many information about the influence of vibration on human body as possible. So far the references show that the major scientific attention has been paid to vertical vibration, although intensive research has been performed lately on the other sorts of excitation. In this paper, the results of the investigation of behavior of human body, in seated position, under the influence of random fore and aft vibration are shown. The investigation is performed by the use of an electro-hydraulic simulator, on a group of 30 healthy male occupants. Experiments are performed in order to give results to improve human body modeling in driving conditions. Excitation amplitudes (1.75 and 2.25 m/s(2) rms) and seat backrest conditions (with and without inclination) were varied. Data results are analyzed by partial coherence and transfer functions. Analyses have been performed and results are given in detail. The results obtained have shown that the human body under the influence of random excitations behaves as a non-linear system and its response depends on spatial position. Obtained results give necessary data to define structure and parameters of human biodynamic model with respect to different excitation and seat backrest position.

The human secretome atlas initiative: Implications in health and disease conditions

PubMed Central

Brown, Kristy J; Seol, Haeri; Pillai, Dinesh K; Sankoorikal, Binu-John; Formolo, Catherine A; Mac, Jenny; Edwards, Nathan J.; Rose, Mary C; Hathout, Yetrib

2013-01-01

Proteomic analysis of human body fluids is highly challenging, therefore many researchers are redirecting efforts towards secretome profiling. The goal is to define potential biomarkers and therapeutic targets in the secretome that can be traced back in accessible human body fluids. However, currently there is a lack of secretome profiles of normal human primary cells making it difficult to assess the biological meaning of current findings. In this study we sought to establish secretome profiles of human primary cells obtained from healthy donors with the goal of building a human secretome atlas. Such an atlas can be used as a reference for discovery of potential disease associated biomarkers and eventually novel therapeutic targets. As a preliminary study, secretome profiles were established for six different types of human primary cell cultures and checked for overlaps with the three major human body fluids including plasma, cerebrospinal fluid and urine. About 67% of the 1054 identified proteins in the secretome of these primary cells occurred in at least one body fluid. Furthermore, comparison of the secretome profiles of two human glioblastoma cell lines to this new human secretome atlas enabled unambiguous identification of potential brain tumor biomarkers. These biomarkers can be easily monitored in different body fluids using stable isotope labeled standard proteins. The long term goal of this study is to establish a comprehensive online human secretome atlas for future use as a reference for any disease related secretome study. PMID:23603790

Modal analysis of human body vibration model for Indian subjects under sitting posture.

PubMed

Singh, Ishbir; Nigam, S P; Saran, V H

2015-01-01

Need and importance of modelling in human body vibration research studies are well established. The study of biodynamic responses of human beings can be classified into experimental and analytical methods. In the past few decades, plenty of mathematical models have been developed based on the diverse field measurements to describe the biodynamic responses of human beings. In this paper, a complete study on lumped parameter model derived from 50th percentile anthropometric data for a seated 54- kg Indian male subject without backrest support under free un-damped conditions has been carried out considering human body segments to be of ellipsoidal shape. Conventional lumped parameter modelling considers the human body as several rigid masses interconnected by springs and dampers. In this study, concept of mass of interconnecting springs has been incorporated and eigenvalues thus obtained are found to be closer to the values reported in the literature. Results obtained clearly establish decoupling of vertical and fore-and-aft oscillations. The mathematical modelling of human body vibration studies help in validating the experimental investigations for ride comfort of a sitting subject. This study clearly establishes the decoupling of vertical and fore-and-aft vibrations and helps in better understanding of possible human response to single and multi-axial excitations.

Heat Exchange in “Human body - Thermal protection - Environment” System

NASA Astrophysics Data System (ADS)

Khromova, I. V.

2017-11-01

This article is devoted to the issues of simulation and calculation of thermal processes in the system called “Human body - Thermal protection - Environment” under low temperature conditions. It considers internal heat sources and convective heat transfer between calculated elements. Overall this is important for the Heat Transfer Theory. The article introduces complex heat transfer calculation method and local thermophysical parameters calculation method in the system called «Human body - Thermal protection - Environment», considering passive and active thermal protections, thermophysical and geometric properties of calculated elements in a wide range of environmental parameters (water, air). It also includes research on the influence that thermal resistance of modern materials, used in special protective clothes development, has on heat transfer in the system “Human body - Thermal protection - Environment”. Analysis of the obtained results allows adding of the computer research data to experiments and optimizing of individual life-support system elements, which are intended to protect human body from exposure to external factors.

Cutting the Flesh: Surgery, Autopsy and Cannibalism in the Belgian Congo

PubMed Central

Au, Sokhieng

2017-01-01

Within the colonial setting of the Belgian Congo, the process of cutting the body, whether living or dead, lent itself to conflation with cannibalism and other fantastic consumption stories by both Congolese and Belgian observers. In part this was due to the instability of the meaning of the human body and the human corpse in the colonial setting. This essay maps out different views of the cadaver and personhood through medical technologies of opening the body in the Belgian Congo. The attempt to impose a specific reading of the human body on the Congolese populations through anatomy and related Western medical disciplines was unsuccessful. Ultimately, practices such as surgery and autopsy were reinterpreted and reshaped in the colonial context, as were the definitions of social and medical death. By examining the conflicts that arose around medical technologies of cutting human flesh, this essay traces multiple parallel narratives on acceptable use and representation of the human body (Congolese or Belgian) beyond its medical assignation. PMID:28260570

Human vocal attractiveness as signaled by body size projection.

PubMed

Xu, Yi; Lee, Albert; Wu, Wing-Li; Liu, Xuan; Birkholz, Peter

2013-01-01

Voice, as a secondary sexual characteristic, is known to affect the perceived attractiveness of human individuals. But the underlying mechanism of vocal attractiveness has remained unclear. Here, we presented human listeners with acoustically altered natural sentences and fully synthetic sentences with systematically manipulated pitch, formants and voice quality based on a principle of body size projection reported for animal calls and emotional human vocal expressions. The results show that male listeners preferred a female voice that signals a small body size, with relatively high pitch, wide formant dispersion and breathy voice, while female listeners preferred a male voice that signals a large body size with low pitch and narrow formant dispersion. Interestingly, however, male vocal attractiveness was also enhanced by breathiness, which presumably softened the aggressiveness associated with a large body size. These results, together with the additional finding that the same vocal dimensions also affect emotion judgment, indicate that humans still employ a vocal interaction strategy used in animal calls despite the development of complex language.

Persons and their bodies: how we should think about human embryos.

PubMed

McLachlan, Hugh V

2002-01-01

The status of human embryos is discussed particularly in the light of the claim by Fox, in Health Care Analysis 8 that it would be useful to think of them in terms of cyborg metaphors. It is argued that we should consider human embryos for what they are--partially formed human bodies--rather than for what they are like in some respects (and unlike in others)--cyborgs. However to settle the issue of the status of the embryo is not to answer the moral questions which arise concerning how embryos should be treated. Since persons rather than bodies have rights, embryos do not have rights. However, whether or not embryos have rights, people can have duties concerning them. Furthermore, the persons whose fully developed bodies embryos will, might (or might have) become can have rights. Contrary to what is often assumed, it is not merely persons who have (or have had) living, developed human bodies who have moral rights: so it is argued in this paper.

75 FR 754 - Safety Zone and Regulated Navigation Area, Chicago Sanitary and Ship Canal, Romeoville, IL

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-06

... barriers would affect a human body if immersed in the water. The NEDU final report concluded that the possible effects to a human body if immersed in the water include paralysis of body muscles, inability to... body of your document so that we can contact you if we have questions regarding your submission. To...

Our Bodies, Our Cells: Children's Activities in Body Systems. Children's Activity Series.

ERIC Educational Resources Information Center

Cahn, Marilyn

The supplemental teaching resources provided in this book offer a variety of concrete, visual activities designed to help classroom and daycare center teachers introduce children to the human body and the way it is organized. An analogy comparing human body parts to house parts is used throughout the book to make lessons clear and age-appropriate.…

[Technology and notion of human life].

PubMed

Kakimoto, Yoshimi

2013-12-01

This article aims to examine the rules of robotics whose sense is modified in society and which change the notion of human body. Asimov proposed three rules of robotics in his novel of science fiction, which become the basis of the rules concerning the study of the development of robotics. These rules are created in order to avoid harming human beings and to mitigate the variant difficulties of being human being. As for latter, robotics has functioned as a meaning of extension of the physical faculty. Thus, technology develops in the direction of the enhancement of the capability of human body beyond the necessities of life. Robotics doesn't only suggest a rethinking of the notion of a human being but also changes our understanding of the human body.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kvon, Evgeny Z.; Kamneva, Olga K.; Melo, Uirá S.

The evolution of body shape is thought to be tightly coupled to changes in regulatory sequences, but specific molecular events associated with major morphological transitions in vertebrates have remained elusive. In this paper, we identified snake-specific sequence changes within an otherwise highly conserved long-range limb enhancer of Sonic hedgehog (Shh). Transgenic mouse reporter assays revealed that the in vivo activity pattern of the enhancer is conserved across a wide range of vertebrates, including fish, but not in snakes. Genomic substitution of the mouse enhancer with its human or fish ortholog results in normal limb development. In contrast, replacement with snake orthologsmore » caused severe limb reduction. Synthetic restoration of a single transcription factor binding site lost in the snake lineage reinstated full in vivo function to the snake enhancer. Our results demonstrate changes in a regulatory sequence associated with a major body plan transition and highlight the role of enhancers in morphological evolution.« less

75 FR 33515 - Federal Motor Vehicle Safety Standards; Electric-Powered Vehicles; Electrolyte Spillage and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-14

..., and made a simple comparison. Based on the IEC report, the human body can withstand up to four times....\\3\\ The flow of this amount of AC through the human body may result in perception of the current and... considered to be safe) corresponds to 8 mA of DC (that is also considered to be safe for the human body).\\4...

42 CFR 417.1 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-10-01

... CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE... paragraph (1). Policymaking body of an HMO means a board of directors, governing body, or other body of..., Bureau of Census, U.S. Department of Commerce). Secretary means the Secretary of Health and Human...

Current perspective on assessment of human body proportions of relevance to amputees.

PubMed

Osterkamp, L K

1995-02-01

Weights of segmental components of the human body are important when evaluating the nutritional status of an amputee. Original standards for components were compiled in 1889 using three male cadavers. Since that time, studies of living subjects have shown men and women to be similar in percentage weight of body components. Cadaver data from 1955 and 1969, which were based on 21 male subjects, showed that human bodies carry greater weight in the head and torso and less weight in legs and arms than indicated by the earlier data. Some differences in component weight may be attributable to ethnicity and aging, but further research is needed to define these differences. The 1955 and 1969 data--whether the result of larger sample size, ethnic differences, or actual change in human body proportions over a 60-year period--are different from the standards for body proportions in the 1889 data, which are presently used, and should be incorporated into the assessment of weight status of amputees.

Human blood metabolite timetable indicates internal body time

PubMed Central

Kasukawa, Takeya; Sugimoto, Masahiro; Hida, Akiko; Minami, Yoichi; Mori, Masayo; Honma, Sato; Honma, Ken-ichi; Mishima, Kazuo; Soga, Tomoyoshi; Ueda, Hiroki R.

2012-01-01

A convenient way to estimate internal body time (BT) is essential for chronotherapy and time-restricted feeding, both of which use body-time information to maximize potency and minimize toxicity during drug administration and feeding, respectively. Previously, we proposed a molecular timetable based on circadian-oscillating substances in multiple mouse organs or blood to estimate internal body time from samples taken at only a few time points. Here we applied this molecular-timetable concept to estimate and evaluate internal body time in humans. We constructed a 1.5-d reference timetable of oscillating metabolites in human blood samples with 2-h sampling frequency while simultaneously controlling for the confounding effects of activity level, light, temperature, sleep, and food intake. By using this metabolite timetable as a reference, we accurately determined internal body time within 3 h from just two anti-phase blood samples. Our minimally invasive, molecular-timetable method with human blood enables highly optimized and personalized medicine. PMID:22927403

Geometric dimension model of virtual astronaut body for ergonomic analysis of man-machine space system

NASA Astrophysics Data System (ADS)

Qianxiang, Zhou

2012-07-01

It is very important to clarify the geometric characteristic of human body segment and constitute analysis model for ergonomic design and the application of ergonomic virtual human. The typical anthropometric data of 1122 Chinese men aged 20-35 years were collected using three-dimensional laser scanner for human body. According to the correlation between different parameters, curve fitting were made between seven trunk parameters and ten body parameters with the SPSS 16.0 software. It can be concluded that hip circumference and shoulder breadth are the most important parameters in the models and the two parameters have high correlation with the others parameters of human body. By comparison with the conventional regressive curves, the present regression equation with the seven trunk parameters is more accurate to forecast the geometric dimensions of head, neck, height and the four limbs with high precision. Therefore, it is greatly valuable for ergonomic design and analysis of man-machine system.This result will be very useful to astronaut body model analysis and application.

A novel missense substitution (Val1483Ile) in the fatty acid synthase gene (FAS) is associated with percentage of body fat and substrate oxidation rates in nondiabetic Pima Indians.

PubMed

Kovacs, Peter; Harper, Inge; Hanson, Robert L; Infante, Aniello M; Bogardus, Clifton; Tataranni, P Antonio; Baier, Leslie J

2004-07-01

Inhibition of fatty acid synthase (FAS) induces a rapid decline in fat stores in mice, suggesting a role for this enzyme in energy homeostasis. The human FAS gene (FAS) maps to chromosome 17q25, a region previously shown to have suggestive linkage to adiposity in a genome-wide linkage scan for genetic determinants of obesity in Pima Indians. To investigate the potential role of FAS in the pathophysiology of human obesity, the FAS gene was sequenced and 13 single nucleotide polymorphisms (SNPs) were identified. Five representative SNPs were genotyped in 216 full-blooded, nondiabetic Pima Indians for association analyses. A Val1483Ile polymorphism (GTC to ATC; allele frequency of A = 0.10) was associated with percentage of body fat and 24-h substrate oxidation rates measured in a respiratory chamber. Compared with homozygotes for the Val variant, subjects with Ile/x had a lower mean percentage of body fat (30 +/- 1 vs. 33 +/- 1%, P = 0.002; adjusted for age, sex, and family membership) and a lower mean carbohydrate oxidation rate (983 +/- 41 vs. 1,094 +/- 19 kcal/day, P = 0.03), which resulted in a lower mean 24-h respiratory quotient (0.845 +/- 0.01 vs. 0.850 +/- 0.01 kcal/day, P = 0.04; both adjusted for age, sex, family membership, percentage of body fat, and energy balance). Our findings indicate that the Val1483Ile substitution in FAS is protective against obesity in Pima Indians, an effect possibly explained by the role of this gene in the regulation of substrate oxidation.

Comparison of sample preparation techniques and data analysis for the LC-MS/MS-based identification of proteins in human follicular fluid.

PubMed

Lehmann, Roland; Schmidt, André; Pastuschek, Jana; Müller, Mario M; Fritzsche, Andreas; Dieterle, Stefan; Greb, Robert R; Markert, Udo R; Slevogt, Hortense

2018-06-25

The proteomic analysis of complex body fluids by liquid chromatography tandem mass spectrometry (LC-MS/MS) analysis requires the selection of suitable sample preparation techniques and optimal parameter settings in data analysis software packages to obtain reliable results. Proteomic analysis of follicular fluid, as a representative of a complex body fluid similar to serum or plasma, is difficult as it contains a vast amount of high abundant proteins and a variety of proteins with different concentrations. However, the accessibility of this complex body fluid for LC-MS/MS analysis is an opportunity to gain insights into the status, the composition of fertility-relevant proteins including immunological factors or for the discovery of new diagnostic and prognostic markers for, for example, the treatment of infertility. In this study, we compared different sample preparation methods (FASP, eFASP and in-solution digestion) and three different data analysis software packages (Proteome Discoverer with SEQUEST, Mascot and MaxQuant with Andromeda) combined with semi- and full-tryptic databank search options to obtain a maximum coverage of the follicular fluid proteome. We found that the most comprehensive proteome coverage is achieved by the eFASP sample preparation method using SDS in the initial denaturing step and the SEQUEST-based semi-tryptic data analysis. In conclusion, we have developed a fractionation-free methodical workflow for in depth LC-MS/MS-based analysis for the standardized investigation of human follicle fluid as an important representative of a complex body fluid. Taken together, we were able to identify a total of 1392 proteins in follicular fluid. © 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Wearable Networked Sensing for Human Mobility and Activity Analytics: A Systems Study.

PubMed

Dong, Bo; Biswas, Subir

2012-01-01

This paper presents implementation details, system characterization, and the performance of a wearable sensor network that was designed for human activity analysis. Specific machine learning mechanisms are implemented for recognizing a target set of activities with both out-of-body and on-body processing arrangements. Impacts of energy consumption by the on-body sensors are analyzed in terms of activity detection accuracy for out-of-body processing. Impacts of limited processing abilities in the on-body scenario are also characterized in terms of detection accuracy, by varying the background processing load in the sensor units. Through a rigorous systems study, it is shown that an efficient human activity analytics system can be designed and operated even under energy and processing constraints of tiny on-body wearable sensors.

Full body photography in the massive weight loss population: an inquiry to optimize patient-centered care.

PubMed

Wasicek, Philip; Kaswan, Sumesh; Messing, Susan; Gusenoff, Jeffrey A

2013-11-01

Medical photography of body contouring patients often requires complete nudity, placing patients in a vulnerable situation. We investigated patient perspectives on full body photography in an effort to better protect the patients and enhance comfort with the photography process. Sixty-five massive weight loss patients were identified who underwent body contouring surgery with full body photography. Photographs were taken at the time of initial consult, time of marking, and postoperatively. A retrospective chart review was performed to assess body mass indices and comorbidities, and a telephone survey inquired about several aspects of the photographic process. Fifty-six (86%) patients participated. Patients were more comfortable at the time of markings (P = 0.0004) and at the postoperative session (P = 0.0009). Patients' perception of positive body image increased after body contouring surgery (P < 0.0001). Patients who reported being comfortable at their initial session had a higher body mass index (P = 0.0027). Professionalism of the staff was rated as the most important aspect of the photographic process. Patients preferring a chaperone of the same sex tended to be less comfortable with the process (P = 0.015). Most patients preferred the surgeon as the photographer (P = 0.03). Patient comfort with full body photography improves quickly as they move through the surgical process. Maintaining professionalism is the most important factor in achieving patient trust and comfort. Limiting the number of observers in the room, providing explicit details of the photography process, and having at least 1 person of the same sex in the room can optimize patient safety and comfort.

Preference for human body odors is influenced by gender and sexual orientation.

PubMed

Martins, Yolanda; Preti, George; Crabtree, Christina R; Runyan, Tamar; Vainius, Aldona A; Wysocki, Charles J

2005-09-01

Human body odor may contribute to selection of partners. If so, sexual orientation may influence preference for and perhaps production of human body odors. In a test of these hypotheses, heterosexual and homosexual males and females made two-alternative forced-choice preference judgments for body odors obtained from other heterosexual and homosexual males and females. Subjects chose between odors from (a) heterosexual males and gay males, (b) heterosexual males and heterosexual females, (c) heterosexual females and lesbians, and (d) gay males and lesbians. Results indicate that differences in body odor are detected and responded to on the basis of, in part, an individual's gender and sexual orientation. Possible mechanisms underlying these findings are discussed.

[F-18-fluordeoxyglucose positron emission tomography on patients with differentiated thyroid cancer who present elevated human serum thyroglobulin levels and negative I-131 whole body scan].

PubMed

Ruiz Franco-Baux, J V; Borrego Dorado, I; Gómez Camarero, P; Rodríguez Rodríguez, J R; Vázquez Albertino, R J; Navarro González, E; Astorga Jiménez, R

2005-01-01

This study aimed to evaluate the role of Fluorine-18-fluorodeoxyglucose positron emission tomography (PET-FDG) in patients with elevated serum thyroglobulin (hTg) levels where thyroid cancer tissue does not concentrate radioiodine, rendering false-negative results on I-131 scanning. Whole-body PET imaging using FDG was performed in 54 patients (37 female, 17 male) aged 17-88 years: 45 with papillary tumors and 9 with follicular tumors who were suspected of having recurrent thyroid carcinoma due to elevated thyroglobulin levels (hTg > 2 ng/ml) under thyroid-stimulating hormone (TSH > or = 30 microIU/ml) in whom the iodine scan was negative. All whole body scans were obtained with diagnostic doses (185 MBq). Whole body PET imaging was performed in fasting patients following i.v. administration of 370 MBq FDG while the patients were receiving full thyroid hormone replacement. Before PET, 99mTc methoxyisobutylisonitrile scintigraphy (99mTc-MIBI) was done in 14 patients and morphologic imaging in 26 by CT scan. Positive PET results confirmed the presence of hypermetabolic foci in 25/54 patients (46.29 %). Positive findings were found for PET-FDG in patients with hTg levels higher than 10 ng/ml receiving full thyroid hormone replacement. 99mTc-MIBI demonstrated lesions in 7/14 patients (50 %). PET-FDG and 99mTc-MIBI had congruent positive results in 4/7 patients. All the lesions found by CT were detected by PET-FDG, while recurrent disease was found in 12/21 patients with previous negative CT. These results suggest that PET-FDG seems to be a promising tool in the follow-up of thyroid cancer and should be considered in patients suffering from differentiated thyroid cancer with suspected recurrence and/or metastases by elevated thyroglobulin levels, and negative I-131 whole body scans. PET-FDG might be more useful at hTg levels > 10 ng/ml.

Presenilin expression during induced differentiation of the human neuroblastoma SH-SY5Y cell line.

PubMed

Flood, Fiona; Sundström, Erik; Samuelsson, Eva-Britt; Wiehager, Birgitta; Seiger, Ake; Johnston, Janet A; Cowburn, Richard F

2004-06-01

Human neuroblastoma SH-SY5Y cells stably transfected with both wild-type and exon-9 deleted (deltaE9) presenilin constructs were used to study the role of the presenilin proteins during differentiation. Cells transfected with either wild-type or deltaE9 PS1, of which the latter abolishes normal endoproteolytic cleavage of the protein, showed no obvious differences in their ability to differentiate to a neuronal-like phenotype upon treatment with retinoic acid (RA). A defined pattern of PS1 expression was observed during differentiation with both RA and the phorbol ester TPA. Full-length PS1 was shown to increase dramatically within 5-24 h of RA treatment. TPA gave an earlier and longer lasting increase in full-length PS1 levels. The intracellular distribution pattern of PS1 was markedly altered following RA treatment. Within 24h PS1 was highly up-regulated throughout the cell body around the nucleus. Between 2 and 4 weeks PS1 staining appeared punctate and also localised to the nucleus. Increases in PS1 expression upon treatment with RA and TPA were blocked by treatment with cycloheximide, indicating a role of de-novo protein synthesis in this effect. PS2 expression remained unchanged during differentiation. Levels of full-length PS1 were also seen to increase during neurogenesis and neuronal differentiation in the forebrain of first trimester human foetuses between 6.5 and 11 weeks. These combined observations support the idea that PS1 is involved in neuronal differentiation by a mechanism likely independent of endoproteolysis of the protein.

[Multifaceted body. 2. The lived body].

PubMed

Wykretowicz, H; Saraga, M; Bourquin, C; Stiefel, F

2015-02-11

The human body is the object upon which medicine is acting, but also lived reality, image, symbol, representation and the object of elaboration and theory. All these elements which constitute the body influence the way medicine is treating it. In this series of three articles, we address the human body from various perspectives: medical (1), phenomenological (2), psychosomatic and socio-anthropological (3). This second article distinguishes between the body as an object of knowledge or representation and the way the body is lived. This distinction which originates in phenomenological psychiatry aims to understand how the patient experiences his body and to surpass the classical somatic and psychiatric classifications.

Voluntary Body Donation: The Gift that Lives on Forever

NASA Astrophysics Data System (ADS)

Saritha, S.; Rao, M. Vittoo; Sumangala; Supriya, G.; Kumar, Praveen

2012-10-01

Body donation is a gracious act, Shankarcharaya firmly believed in concept of Body Donation or Organ Donation and said Iddham sharirum paropakarum i.e. the body is for use of others and death is not the end, it is the beginning. Anatomy is important basic subject for medicalstudents, both U.G. & P.G. Best method of Anatomy learning is by dissection on human cadavers, which remains principle teaching tool. Human cadavers for purpose of study are a scarcity with mushrooming of medical institutions in this country. Unclaimed bodies are no more origin of cadavers. Whole Body donation is the need of the hour. A Voluntary Body Donation is defined as the act of giving oneís Body after death for Medical research and education. In this article a survey was done in S.V.S. Medical & Dental Colleges Faculty members and medical exhibition visitors which include lawyers, engineers, teachers and others during the year of 2010. The body donation including organ donation and various factors such as age, religion, culture and donorís attitude are discussed. Body donation provides the students and medical researchers with unparalleled opportunities to study the human body. Computers nor books cannot totally replace body dissection in learning the anatomy.

Modeling and characterization of different channels based on human body communication.

PubMed

Jingzhen Li; Zedong Nie; Yuhang Liu; Lei Wang

2017-07-01

Human body communication (HBC), which uses the human body as a transmission medium for electrical signals, provides a prospective communication solution for body sensor networks (BSNs). In this paper, an inhomogeneous model which includes the tissue layers of skin, fat, and muscle is proposed to study the propagation characteristics of different HBC channels. Specifically, the HBC channels, namely, the on-body to on-body (OB-OB)channel, on-body to in-body (OB-IB) channel, in-body to on-body (IB-OB) channel, and in-body to in-body (IB-IB)channel, are studied over different frequencies (from 1MHz to 100MHz) through numerical simulations with finite-difference time-domain (FDTD) method. The results show that the gain of OB-IB channel and IB-OB channel is almost the same. The gain of IB-IB channel is greater than other channels in the frequency range 1MHz to 70MHz. In addition, the gain of all channels is associated with the channel length and communication frequency. The simulations are verified by experimental measurements in a porcine tissue sample. The results show that the simulations are in agreement with the measurements.

Assessment by near-infrared spectroscopy of the consumption of oxygen provoked by the human body weight in the vastus medialis muscle

NASA Astrophysics Data System (ADS)

Verdaguer-Codina, Joan

1996-12-01

This study has been focused to find the importance of the consumption of oxygen for a muscle that works supporting the weight of the human body. The oxygen uptake at rest level is a data know, but by near-IR spectroscopy can be assessed the oxygen uptake used for a muscle. The energy required by the human body is partially used to produce the energy that help to move the human structure. The oxygen required by the muscles to produce the energy to support the human body has been defined as weight oxygen consumption. The purpose of this study was to assess by near-IR spectroscopy the amount of relative oxygenation/deoxygenation that a muscle requires at rest level and a middle-term rest level.

Revised Estimates for the Number of Human and Bacteria Cells in the Body.

PubMed

Sender, Ron; Fuchs, Shai; Milo, Ron

2016-08-01

Reported values in the literature on the number of cells in the body differ by orders of magnitude and are very seldom supported by any measurements or calculations. Here, we integrate the most up-to-date information on the number of human and bacterial cells in the body. We estimate the total number of bacteria in the 70 kg "reference man" to be 3.8·1013. For human cells, we identify the dominant role of the hematopoietic lineage to the total count (≈90%) and revise past estimates to 3.0·1013 human cells. Our analysis also updates the widely-cited 10:1 ratio, showing that the number of bacteria in the body is actually of the same order as the number of human cells, and their total mass is about 0.2 kg.

Revised Estimates for the Number of Human and Bacteria Cells in the Body

PubMed Central

Milo, Ron

2016-01-01

Reported values in the literature on the number of cells in the body differ by orders of magnitude and are very seldom supported by any measurements or calculations. Here, we integrate the most up-to-date information on the number of human and bacterial cells in the body. We estimate the total number of bacteria in the 70 kg "reference man" to be 3.8·1013. For human cells, we identify the dominant role of the hematopoietic lineage to the total count (≈90%) and revise past estimates to 3.0·1013 human cells. Our analysis also updates the widely-cited 10:1 ratio, showing that the number of bacteria in the body is actually of the same order as the number of human cells, and their total mass is about 0.2 kg. PMID:27541692

Human Biology, High School Science Course Guide.

ERIC Educational Resources Information Center

Donovan, Edward P.; Prickitt, Ralph

A course in human biology was developed to increase course options for students of all abilities and interest levels who successfully completed 1 year of high school science. Major topic areas of the course include: general plan of the human body; causes, cures, and prevention of diseases; human body chemistry; structure and function of cells,…

75 FR 53577 - Choline hydroxide; Exemption from the Requirement of a Tolerance

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-01

... endogenously in the human body. Humans are currently exposed to choline on a daily basis through commonly eaten... dietary consumption of choline, choline is made endogenously in the human body. Choline is a precursor to... human health. In order to determine the risks from aggregate exposure to pesticide inert ingredients...

Aspects of human biometeorology in past, present and future.

PubMed

Höppe, P

1997-02-01

Human biometeorology is quite an old science: during the times of Hippokrates in ancient Greece the influence of weather changes on physiological processes in the human body were considered to exist. However, not until the progress in modern statistics, physics and physiology in the course of this century provided quantitative methods did human-biometeorology become an acknowledged natural science. In the first half of this century primarily the explanation of the phenomena of reactions of the body to weather changes was the general objective. In the second half of this century quantitative descriptions of thermal interchanges between the human body and the environment by means of energy balance models of the human body have gained increasing importance. The methods of modern human biometeorology increasingly are acknowledged by workers in disciplines of potential application, such as urban or regional planners or air conditioning engineers. Human biometeorology tries to assess all atmospheric influences in its entirety, including the air pollution pattern. The discipline considers itself as branch of science which is tied closely to environmental meteorology and environmental medicine.

42 CFR 411.351 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... of materials derived from the human body for the purpose of providing information for the diagnosis..., or other examination of materials derived from the human body for the purpose of providing... CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES MEDICARE PROGRAM...

The "spare parts person"? Conceptions of the human body and their implications for public attitudes towards organ donation and organ sale

PubMed Central

Schweda, Mark; Schicktanz, Silke

2009-01-01

Background The increasing debate on financial incentives for organ donation raises concerns about a "commodification of the human body". Philosophical-ethical stances on this development depend on assumptions concerning the body and how people think about it. In our qualitative empirical study we analyze public attitudes towards organ donation in their specific relation to conceptions of the human body in four European countries (Cyprus, Germany, the Netherlands and Sweden). This approach aims at a more context-sensitive picture of what "commodification of the body" can mean in concrete clinical decisions concerning organ donation. Results We find that moral intuitions concerning organ donation are rooted in various conceptions of the human body and its relation to the self: a) the body as a mechanical object owned by the self, b) the body as a part of a higher order embodying the self, and c) the body as a hierarchy of organs constitutive of the self. Conclusion The language of commodification is much too simple to capture what is at stake in everyday life intuitions about organ donation and organ sale. We discuss how the plurality of underlying body-self conceptions can be taken into account in the ethical debate, pointing out consequences for an anthropologically informed approach and for a liberal perspective. PMID:19226449

Reprint of: Cling film plastic wrap: An innovation for dead body packaging, preservation and transportation by first responders as a replacement for cadaver body bag in large scale disasters.

PubMed

Khoo, Lay See; Lai, Poh Soon; Saidin, Mohd Hilmi; Noor, Zahari; Mahmood, Mohd Shah

2018-07-01

Cadaver body bags are the conventional method to contain a human body or human remains, which includes the use for storage and transportation of the deceased at any crime scene or disaster scene. During disasters, most often than not, the first responders including the police will be equipped with cadaver body bags to do scene processing of human remains and collection of personal belongings at the disaster site. However, in an unanticipated large scale disasters involving hundreds and thousands of fatalities, cadaver body bags supplies may be scarce. The authors have therefore innovated the cling film plastic wrap as an alternative for the cadaver body bag used at the disaster site. The plastic wrap was tested on six different experimental subjects, i.e. both adult and child mannequins; body parts of the mannequin figure (arm and hand); a human adult subject and an unknown dead body. The strengths of the cling film plastic wrap are discussed in comparison with the cadaver body bag in the aspects of costing, weight, duration of the wrap, water and body fluid resistant properties, visibility and other advantages. An average savings of more than 5000% are noted for both adult body wrap and child body wrap compared to the cadaver body wrap. This simply means that the authors can either wrap 25 adult dead bodies or 80 children dead bodies with the cost of 1 cadaver body bag. The cling film plastic wrap has proven to have significant innovation impact for dead body management particularly by the first responders in large scale disasters. With proper handling of dead bodies, first responders can manage the dead with dignity and respect in an overwhelmed situation to facilitate the humanitarian victim identification process later. Copyright © 2018 Elsevier B.V. All rights reserved.

Cling film plastic wrap: An innovation for dead body packaging, preservation and transportation by first responders as a replacement for cadaver body bag in large scale disasters.

PubMed

Khoo, Lay See; Lai, Poh Soon; Saidin, Mohd Hilmi; Noor, Zahari; Mahmood, Mohd Shah

2018-04-01

Cadaver body bags are the conventional method to contain a human body or human remains, which includes the use for storage and transportation of the deceased at any crime scene or disaster scene. During disasters, most often than not, the first responders including the police will be equipped with cadaver body bags to do scene processing of human remains and collection of personal belongings at the disaster site. However, in an unanticipated large scale disasters involving hundreds and thousands of fatalities, cadaver body bags supplies may be scarce. The authors have therefore innovated the cling film plastic wrap as an alternative for the cadaver body bag used at the disaster site. The plastic wrap was tested on six different experimental subjects, i.e. both adult and child mannequins; body parts of the mannequin figure (arm and hand); a human adult subject and an unknown dead body. The strengths of the cling film plastic wrap are discussed in comparison with the cadaver body bag in the aspects of costing, weight, duration of the wrap, water and body fluid resistant properties, visibility and other advantages. An average savings of more than 5000% are noted for both adult body wrap and child body wrap compared to the cadaver body wrap. This simply means that the authors can either wrap 25 adult dead bodies or 80 children dead bodies with the cost of 1 cadaver body bag. The cling film plastic wrap has proven to have significant innovation impact for dead body management particularly by the first responders in large scale disasters. With proper handling of dead bodies, first responders can manage the dead with dignity and respect in an overwhelmed situation to facilitate the humanitarian victim identification process later. Copyright © 2018 Elsevier B.V. All rights reserved.

47 CFR 95.628 - MedRadio transmitters.

Code of Federal Regulations, 2011 CFR

2011-10-01

... human body, radiated emissions and EIRP measurements for transmissions by stations authorized under this section may be made in accordance with a Commission-approved human body simulator and test technique. A... from a medical implant or medical body-worn device on that channel. The MedRadio communications session...

47 CFR 95.628 - MedRadio transmitters.

Code of Federal Regulations, 2010 CFR

2010-10-01

... human body, radiated emissions and EIRP measurements for transmissions by stations authorized under this section may be made in accordance with a Commission-approved human body simulator and test technique. A... from a medical implant or medical body-worn device on that channel. The MedRadio communications session...

Classic versus millennial medical lab anatomy.

PubMed

Benninger, Brion; Matsler, Nik; Delamarter, Taylor

2014-10-01

This study investigated the integration, implementation, and use of cadaver dissection, hospital radiology modalities, surgical tools, and AV technology during a 12-week contemporary anatomy course suggesting a millennial laboratory. The teaching of anatomy has undergone the greatest fluctuation of any of the basic sciences during the past 100 years in order to make room for the meteoric rise in molecular sciences. Classically, anatomy consisted of a 2-year methodical, horizontal, anatomy course; anatomy has now morphed into a 12-week accelerated course in a vertical curriculum, at most institutions. Surface and radiological anatomy is the language for all clinicians regardless of specialty. The objective of this study was to investigate whether integration of full-body dissection anatomy and modern hospital technology, during the anatomy laboratory, could be accomplished in a 12-week anatomy course. Literature search was conducted on anatomy text, journals, and websites regarding contemporary hospital technology integrating multiple image mediums of 37 embalmed cadavers, surgical suite tools and technology, and audio/visual technology. Surgical and radiology professionals were contracted to teach during the anatomy laboratory. Literature search revealed no contemporary studies integrating full-body dissection with hospital technology and behavior. About 37 cadavers were successfully imaged with roentograms, CT, and MRI scans. Students were in favor of the dynamic laboratory consisting of multiple activity sessions occurring simultaneously. Objectively, examination scores proved to be a positive outcome and, subjectively, feedback from students was overwhelmingly positive. Despite the surging molecular based sciences consuming much of the curricula, full-body dissection anatomy is irreplaceable regarding both surface and architectural, radiological anatomy. Radiology should not be a small adjunct to understand full-body dissection, but rather, full-body dissection aids the understanding of radiology mediums. The millennial anatomy dissection laboratory should consist of, at least, 50% radiology integration during full-body dissection. This pilot study is an example of the most comprehensive integration of full-body dissection, radiology, and hospital technology. © 2014 Wiley Periodicals, Inc.

Body composition in Pan paniscus compared with Homo sapiens has implications for changes during human evolution.

PubMed

Zihlman, Adrienne L; Bolter, Debra R

2015-06-16

The human body has been shaped by natural selection during the past 4-5 million years. Fossils preserve bones and teeth but lack muscle, skin, fat, and organs. To understand the evolution of the human form, information about both soft and hard tissues of our ancestors is needed. Our closest living relatives of the genus Pan provide the best comparative model to those ancestors. Here, we present data on the body composition of 13 bonobos (Pan paniscus) measured during anatomical dissections and compare the data with Homo sapiens. These comparative data suggest that both females and males (i) increased body fat, (ii) decreased relative muscle mass, (iii) redistributed muscle mass to lower limbs, and (iv) decreased relative mass of skin during human evolution. Comparison of soft tissues between Pan and Homo provides new insights into the function and evolution of body composition.

A human body model for efficient numerical characterization of UWB signal propagation in wireless body area networks.

PubMed

Lim, Hooi Been; Baumann, Dirk; Li, Er-Ping

2011-03-01

Wireless body area network (WBAN) is a new enabling system with promising applications in areas such as remote health monitoring and interpersonal communication. Reliable and optimum design of a WBAN system relies on a good understanding and in-depth studies of the wave propagation around a human body. However, the human body is a very complex structure and is computationally demanding to model. This paper aims to investigate the effects of the numerical model's structure complexity and feature details on the simulation results. Depending on the application, a simplified numerical model that meets desired simulation accuracy can be employed for efficient simulations. Measurements of ultra wideband (UWB) signal propagation along a human arm are performed and compared to the simulation results obtained with numerical arm models of different complexity levels. The influence of the arm shape and size, as well as tissue composition and complexity is investigated.

Body composition in Pan paniscus compared with Homo sapiens has implications for changes during human evolution

PubMed Central

Zihlman, Adrienne L.; Bolter, Debra R.

2015-01-01

The human body has been shaped by natural selection during the past 4–5 million years. Fossils preserve bones and teeth but lack muscle, skin, fat, and organs. To understand the evolution of the human form, information about both soft and hard tissues of our ancestors is needed. Our closest living relatives of the genus Pan provide the best comparative model to those ancestors. Here, we present data on the body composition of 13 bonobos (Pan paniscus) measured during anatomical dissections and compare the data with Homo sapiens. These comparative data suggest that both females and males (i) increased body fat, (ii) decreased relative muscle mass, (iii) redistributed muscle mass to lower limbs, and (iv) decreased relative mass of skin during human evolution. Comparison of soft tissues between Pan and Homo provides new insights into the function and evolution of body composition. PMID:26034269

UWB pulse propagation into human tissues

NASA Astrophysics Data System (ADS)

Cavagnaro, Marta; Pittella, Erika; Pisa, Stefano

2013-12-01

In this paper the propagation of a UWB pulse into a layered model of the human body is studied to characterize absorption and reflection of the UWB signal due to the different body tissues. Several time behaviours for the incident UWB pulse are considered and compared with reference to the feasibility of breath and heartbeat activity monitoring. Results show that if the UWB source is placed far from the human body, the reflection coming from the interface between air and skin can be used to detect the respiratory activity. On the contrary, if the UWB source is placed close to the human body, a small reflection due to the interface between the posterior lung wall and the bone, which is well distanced in time from the reflections due to the first layers of the body model, can be used to detect lung and heart changes associated with the cardio-respiratory activity.

75 FR 36288 - Amended Safety Zone and Regulated Navigation Area, Chicago Sanitary and Ship Canal, Romeoville, IL

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-25

... current from the barriers would affect a human body if immersed in the water. The NEDU final report concluded that the possible effects to a human body if immersed in the water include paralysis of body... address, an e-mail address, or a telephone number in the body of your document so that we can contact you...

75 FR 75145 - Regulated Navigation Area, Chicago Sanitary and Ship Canal, Romeoville, IL; Safety Zone, Chicago...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-02

... current from the barriers would affect a human body if immersed in the water. The NEDU final report concluded that the possible effects to a human body if immersed in the water include paralysis of body..., an e-mail address, or a telephone number in the body of your document so that we can contact you if...

Comparison of Biophysical Characteristics and Predicted Thermophysiological Responses of Three Prototype Body Armor Systems Versus Baseline U.S. Army Body Armor Systems

DTIC Science & Technology

2015-06-19

effective and scientifically valid method of making comparisons of clothing and equipment changes prior to conducting human research. predictive modeling...valid method of making comparisons of clothing and equipment changes prior to conducting human research. 2 INTRODUCTION Modern day...clothing and equipment changes prior to conducting human research. METHODS Ensembles Three different body armor (BA) plus clothing ensembles were

Updates to Blast Injury Criteria Models for Nuclear Casualty Estimation

DTIC Science & Technology

2015-12-01

the likelihood of blast-related injury use a two-step process. First, the maximum velocity obtained by the human body or secondary missile is determined...the human body . Secondary injuries are caused by missiles that are accelerated by the blast wave. Tertiary injuries are caused by the acceleration of...the human body and the ensuing deceleration. In this work, we focus on secondary and tertiary injuries. Because of the dramatic effects experienced

Imaging of ultraweak spontaneous photon emission from human body displaying diurnal rhythm.

PubMed

Kobayashi, Masaki; Kikuchi, Daisuke; Okamura, Hitoshi

2009-07-16

The human body literally glimmers. The intensity of the light emitted by the body is 1000 times lower than the sensitivity of our naked eyes. Ultraweak photon emission is known as the energy released as light through the changes in energy metabolism. We successfully imaged the diurnal change of this ultraweak photon emission with an improved highly sensitive imaging system using cryogenic charge-coupled device (CCD) camera. We found that the human body directly and rhythmically emits light. The diurnal changes in photon emission might be linked to changes in energy metabolism.

Study of performance and propagation characteristics of wire and planar structures around human body.

PubMed

Aroul, A L Praveen; Bhatia, Dinesh

2011-01-01

Continued miniaturization of electronic devices and technological advancements in wireless communications has made wearable body-centric telemedicine systems viable. Antennas play a crucial role in characterizing the efficiency and reliability of these systems. The performance characteristics such as the radiation pattern, gain, efficiency of the antennas get adversely affected due to the presence of lossy human body tissues. In this paper we investigate the above mentioned performance parameters and radio frequency transmission properties of wire and planar structures operating at ISM frequency band of 2.40-2.50 GHz in the proximity of human body.

Lorcaserin, a novel selective human 5-hydroxytryptamine2C agonist: in vitro and in vivo pharmacological characterization.

PubMed

Thomsen, William J; Grottick, Andrew J; Menzaghi, Frederique; Reyes-Saldana, Hazel; Espitia, Stephen; Yuskin, Diane; Whelan, Kevin; Martin, Michael; Morgan, Michael; Chen, Weichao; Al-Shamma, Hussien; Smith, Brian; Chalmers, Derek; Behan, Dominic

2008-05-01

5-Hydroxytryptamine (5-HT)(2C) receptor agonists hold promise for the treatment of obesity. In this study, we describe the in vitro and in vivo characteristics of lorcaserin [(1R)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3 benzazepine], a selective, high affinity 5-HT(2C) full agonist. Lorcaserin bound to human and rat 5-HT(2C) receptors with high affinity (K(i) = 15 +/- 1 nM, 29 +/- 7 nM, respectively), and it was a full agonist for the human 5-HT(2C) receptor in a functional inositol phosphate accumulation assay, with 18- and 104-fold selectivity over 5-HT(2A) and 5-HT(2B) receptors, respectively. Lorcaserin was also highly selective for human 5-HT(2C) over other human 5-HT receptors (5-HT(1A), 5-HT(3), 5-HT(4C), 5-HT5(5A), 5-HT(6), and 5-HT(7)), in addition to a panel of 67 other G protein-coupled receptors and ion channels. Lorcaserin did not compete for binding of ligands to serotonin, dopamine, and norepinephrine transporters, and it did not alter their function in vitro. Behavioral observations indicated that unlike the 5-HT(2A) agonist (+/-)-1-(2,5-dimethoxy-4-phenyl)-2-aminopropane, lorcaserin did not induce behavioral changes indicative of functional 5-HT(2A) agonist activity. Acutely, lorcaserin reduced food intake in rats, an effect that was reversed by pretreatment with the 5-HT(2C)-selective antagonist 6-chloro-5-methyl-1-[6-(2-methylpyridin-3-yloxy)pyridin-3-yl-carbamoyl]indoline (SB242,084) but not the 5-HT(2A) antagonist (R)-(+)-alpha-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenylethyl)]-4-piperidine-methanol (MDL 100,907), demonstrating mediation by the 5-HT(2C) receptor. Chronic daily treatment with lorcaserin to rats maintained on a high fat diet produced dose-dependent reductions in food intake and body weight gain that were maintained during the 4-week study. Upon discontinuation, body weight returned to control levels. These data demonstrate lorcaserin to be a potent, selective, and efficacious agonist of the 5-HT(2C) receptor, with potential for the treatment of obesity.

Full-Body Gaze Control Mechanisms Elicited During Locomotion: Effects Of VOR Adaptation

NASA Technical Reports Server (NTRS)

Mulavara, A. P.; Houser, J.; Peters, B.; Miller, C.; Richards, J.; Marshburn, A.; Brady, R.; Cohen, H.; Bloomberg, J. J.

2004-01-01

Control of locomotion requires precise interaction between several sensorimotor subsystems. During locomotion the performer must satisfy two performance criteria: maintain stable forward translation and to stabilize gaze (McDonald, et al., 1997). Precise coordination demands integration of multiple sensorimotor subsystems for fulfilling both criteria. In order to test the general hypothesis that the whole body can serve as an integrated gaze stabilization system, we have previously investigated how the multiple, interdependent full-body sensorimotor subsystems respond to changes in gaze stabilization task constraints during locomotion (Mulavara and Bloomberg, 2003). The results suggest that the full body contributes to gaze stabilization during locomotion, and that its different functional elements respond to changes in visual task constraints. The goal of this study was to determine how the multiple, interdependent, full-body sensorimotor subsystems aiding gaze stabilization during locomotion are functionally coordinated after the vestibulo-ocular reflex (VOR) gain has been altered. We investigated the potential of adaptive remodeling of the full-body gaze control system following exposure to visual-vestibular conflict known to adaptively reduce the VOR. Subjects (n=14) walked (6.4 km/h) on the treadmill before and after they were exposed to 0.5X manifying lenses worn for 30 minutes during self-generated sinusoidal vertical head rotations performed while seated. In this study we measured: temporal parameters of gait, full body sagittal plane segmental kinematics of the head, trunk, thigh, shank and foot, accelerations along the vertical axis at the head and the shank, and the vertical forces acting on the support surface. Results indicate that, following exposure to the 0.5X minifying lenses, there was a significant increase in the duration of stance and stride times, alteration in the amplitude of head movement with respect to space and a significant increase in the amount of knee flexion during the initial stance phase of the gait cycle. This study provides further evidence that the full body contributes to gaze stabilization during locomotion, and that different functional elements are responsive to changes in visual task constraints and are subject to adaptive alteration following exposure to visual-vestibular conflict.

32 CFR 218.3 - Dose reconstruction methodology.

Code of Federal Regulations, 2010 CFR

2010-07-01

... each source of radiation. Detailed modeling of the human body, in appropriate postures in the trench... radiation field does not reflect the shielding of the film badge afforded by the human body. This shielding has been determined for pertinent body positions by the solution of radiation transport equations as...

32 CFR 218.3 - Dose reconstruction methodology.

Code of Federal Regulations, 2011 CFR

2011-07-01

... each source of radiation. Detailed modeling of the human body, in appropriate postures in the trench... radiation field does not reflect the shielding of the film badge afforded by the human body. This shielding has been determined for pertinent body positions by the solution of radiation transport equations as...

Body parts and the market place: insights from Thomistic philosophy.

PubMed

Cherry, M J

2000-08-01

With rare exceptions, Roman Catholic moral theologians condemn the sale of human organs for transplantation. Yet, such criticism, while rhetorically powerful, often oversimplifies complex issues. Arguments for the prohibition of a market in human organs may, therefore, depend on a single premise, or a cluster of dubious and allied premises, which when examined cannot hold. In what follows, I will examine the ways in which such arguments are configured. For example, Thomas Aquinas' (1224-1274) understandings of embodiment and moral uses of the body are usually interpreted as, and cited in support of, foreclosing a market in human organs. Aquinas' principle of totality requires that one preserve the wholeness of the human body. In approaching Aquinas' texts, I will assume the role of a revisionist who takes seriously his core commitments, while at the same time indicating that one can further develop his understanding of the body in ways which are supportive of the sale of human organs while remaining in conformity with the author's core concerns. Such considerations will provide significant grounds for concluding that a market in human organs for transplantation appreciates the embodied nature of the human person, respects the body and its parts as personal, rather than as mere things, is consistent with acknowledging God's dominion over our lives and bodies, and constitutes an appropriate utilization of God's gifts to us. Moreover, such a market would likely create significant opportunities charitably to help others, to enhance human dignity and to protect against the serious dehumanization of current national bureaucratic procedures for organ donation.

The impact of Body Worlds on adult visitors' knowledge on human anatomy: A preliminary study.

PubMed

Fonseca, Guilherme R B C; Finn, Gabrielle M

2016-05-01

Body Worlds is an anatomical exhibition that shows human remains to the public. It has been considered controversial since it raises ethical tensions and issues. However, organizers and supporters of Body Worlds have claimed the exhibition is intended to promote visitors' understanding over the human body. Despite these claims, no studies were found that support or refute the hypothesis that a visit to Body Worlds increases the public's objective knowledge on human anatomy. Consequently, the objective of this study was to determine the impact of Body Worlds on anatomical knowledge. We constructed and delivered a questionnaire to both a previsit random sample and a postvisit random sample of visitors of Body Worlds' event Facets of Life, in Berlin. The questionnaire was available in both English and German languages and contained (a) basic sociodemographic questions and (b) a valid and reliable anatomy quiz. The quiz consisted of 16 multiple-choice questions that assessed the ability to identify the location of major anatomical structures on the human body. Average scores achieved on the quiz by the postvisit sample (X¯= 9.08, s = 2.48, n = 164) were significantly higher (unpaired t = 3.3957, P = 0.0008) than those achieved by the previsit sample (X¯= 8.11, s = 2.69, n = 167). Our results suggest that a visit to Body Worlds' event Facets of Life may have a beneficial effect in anatomical knowledge. However, further studies with better empirical designs and fewer limitations are needed to confirm our results. © 2016 Wiley Periodicals, Inc.

Recruiting Human Microbiome Shotgun Data to Site-Specific Reference Genomes

PubMed Central

Xie, Gary; Lo, Chien-Chi; Scholz, Matthew; Chain, Patrick S. G.

2014-01-01

The human body consists of innumerable multifaceted environments that predispose colonization by a number of distinct microbial communities, which play fundamental roles in human health and disease. In addition to community surveys and shotgun metagenomes that seek to explore the composition and diversity of these microbiomes, there are significant efforts to sequence reference microbial genomes from many body sites of healthy adults. To illustrate the utility of reference genomes when studying more complex metagenomes, we present a reference-based analysis of sequence reads generated from 55 shotgun metagenomes, selected from 5 major body sites, including 16 sub-sites. Interestingly, between 13% and 92% (62.3% average) of these shotgun reads were aligned to a then-complete list of 2780 reference genomes, including 1583 references for the human microbiome. However, no reference genome was universally found in all body sites. For any given metagenome, the body site-specific reference genomes, derived from the same body site as the sample, accounted for an average of 58.8% of the mapped reads. While different body sites did differ in abundant genera, proximal or symmetrical body sites were found to be most similar to one another. The extent of variation observed, both between individuals sampled within the same microenvironment, or at the same site within the same individual over time, calls into question comparative studies across individuals even if sampled at the same body site. This study illustrates the high utility of reference genomes and the need for further site-specific reference microbial genome sequencing, even within the already well-sampled human microbiome. PMID:24454771

Alternative complement pathway activation increases mortality in a model of burn injury in mice.

PubMed Central

Gelfand, J A; Donelan, M; Hawiger, A; Burke, J F

1982-01-01

We have studied the role of the complement system in burn injury in an experimental model in mice. A 25% body surface area, full-thickness scald wound was produced in anesthetized animals. Massive activation of the alternative complement pathway, but not the classical pathway, was seen. This activation was associated with the generation of neutrophil aggregating activity in the plasma, neutrophil aggregates in the lungs, increased pulmonary vascular permeability, and increased lung edema formation. Decomplementation with cobra venom factor (CVF) or genetic C5 deficiency diminished these pathologic changes, and CVF pretreatment substantially reduced burn mortality in the first 24 h. Preliminary data show that human burn patients have a similar pattern of complement activation involving predominantly the alternative pathway, indicating the possible relevance of the murine model to human disease. Images PMID:7174787

Research on the Multiple Factors Influencing Human Identification Based on Pyroelectric Infrared Sensors

PubMed Central

Lou, Ping; Hu, Jianmin

2018-01-01

Analysis of the multiple factors affecting human identification ability based on pyroelectric infrared technology is a complex problem. First, we examine various sensed pyroelectric waveforms of the human body thermal infrared signal and reveal a mechanism for affecting human identification. Then, we find that the mechanism is decided by the distance, human target, pyroelectric infrared (PIR) sensor, the body type, human moving velocity, signal modulation mask, and Fresnel lens. The mapping relationship between the sensed waveform and multiple influencing factors is established, and a group of mathematical models are deduced which fuse the macro factors and micro factors. Finally, the experimental results show the macro-factors indirectly affect the recognition ability of human based on the pyroelectric technology. At the same time, the correctness and effectiveness of the mathematical models is also verified, which make it easier to obtain more pyroelectric infrared information about the human body for discriminating human targets. PMID:29462908

Robotic Missions to Small Bodies and Their Potential Contributions to Human Exploration and Planetary Defense

NASA Technical Reports Server (NTRS)

Abell, Paul A.; Rivkin, Andrew S.

2015-01-01

Introduction: Robotic missions to small bodies will directly address aspects of NASA's Asteroid Initiative and will contribute to future human exploration and planetary defense. The NASA Asteroid Initiative is comprised of two major components: the Grand Challenge and the Asteroid Mission. The first component, the Grand Challenge, focuses on protecting Earth's population from asteroid impacts by detecting potentially hazardous objects with enough warning time to either prevent them from impacting the planet, or to implement civil defense procedures. The Asteroid Mission involves sending astronauts to study and sample a near-Earth asteroid (NEA) prior to conducting exploration missions of the Martian system, which includes Phobos and Deimos. The science and technical data obtained from robotic precursor missions that investigate the surface and interior physical characteristics of an object will help identify the pertinent physical properties that will maximize operational efficiency and reduce mission risk for both robotic assets and crew operating in close proximity to, or at the surface of, a small body. These data will help fill crucial strategic knowledge gaps (SKGs) concerning asteroid physical characteristics that are relevant for human exploration considerations at similar small body destinations. These data can also be applied for gaining an understanding of pertinent small body physical characteristics that would also be beneficial for formulating future impact mitigation procedures. Small Body Strategic Knowledge Gaps: For the past several years NASA has been interested in identifying the key SKGs related to future human destinations. These SKGs highlight the various unknowns and/or data gaps of targets that the science and engineering communities would like to have filled in prior to committing crews to explore the Solar System. An action team from the Small Bodies Assessment Group (SBAG) was formed specifically to identify the small body SKGs under the direction of the Human Exploration and Operations Missions Directorate (HEOMD), given NASA's recent interest in NEAs and the Martian moons as potential human destinations. The action team organized the SKGs into four broad themes: 1) Identify human mission targets; 2) Understand how to work on and interact with the small body surface; 3) Understand the small body environment and its potential risk/benefit to crew, systems, and operational assets; and 4) Understand the small body resource potential. Of these four SKG themes, the first three have significant overlap with planetary defense considerations. The data obtained from investigations of small body physical characteristics under these three themes can be directly applicable to planetary defense initiatives. Conclusions: Missions to investigate small bodies can address small body strategic knowledge gaps and contribute to the overall success for human exploration missions to asteroids and the Martian moons. In addition, such reconnaissance of small bodies can also provide a wealth of information relevant to the science and planetary defense of NEAs.

Effect of the Environmental Stimuli upon the Human Body in Winter Outdoor Thermal Environment

PubMed Central

Kurazumi, Yoshihito; Kondo, Emi; Ishii, Jin; Sakoi, Tomonori; Fukagawa, Kenta; Bolashikov, Zhecho Dimitrov; Tsuchikawa, Tadahiro; Matsubara, Naoki; Horikoshi, Tetsumi

2013-01-01

In order to manage the outdoor thermal environment with regard to human health and the environmental impact of waste heat, quantitative evaluations are indispensable. It is necessary to use a thermal environment evaluation index. The purpose of this paper is to clarify the relationship between the psychological thermal responses of the human body and winter outdoor thermal environment variables. Subjective experiments were conducted in the winter outdoor environment. Environmental factors and human psychological responses were measured. The relationship between the psychological thermal responses of the human body and the outdoor thermal environment index ETFe (enhanced conduction-corrected modified effective temperature) in winter was shown. The variables which influence the thermal sensation vote of the human body are air temperature, long-wave thermal radiation and short-wave solar radiation. The variables that influence the thermal comfort vote of the human body are air temperature, humidity, short-wave solar radiation, long-wave thermal radiation, and heat conduction. Short-wave solar radiation, and heat conduction are among the winter outdoor thermal environment variables that affect psychological responses to heat. The use of thermal environment evaluation indices that comprise short-wave solar radiation and heat conduction in winter outdoor spaces is a valid approach. PMID:23861691

The morphology of human hyoid bone in relation to sex, age and body proportions.

PubMed

Urbanová, P; Hejna, P; Zátopková, L; Šafr, M

2013-06-01

Morphological aspects of the human hyoid bone are, like many other skeletal elements in human body, greatly affected by individual's sex, age and body proportions. Still, the known sex-dependent bimodality of a number of body size characteristics overshadows the true within-group patterns. Given the ambiguity of the causal effects of age, sex and body size upon hyoid morphology the present study puts the relationship between shape of human hyoid bone and body proportions (height and weight) under scrutiny of a morphological study. Using 211 hyoid bones and landmark-based methods of geometric morphometrics, it was shown that the size of hyoid bones correlated positively with measured body dimensions but showed no correlation if the individual's sex was controlled for. For shape variables, our results revealed that hyoid morphology is clearly related to body size as expressed in terms of the height and weight. Yet, the hyoid shape was shown to result primarily from the sex-related bimodal distribution of studied body size descriptors which, in the case of the height-dependent model, exhibited opposite trends for males and females. Apart from the global hyoid shape given by spatial arrangements of the greater horns, body size dependency was translated into size and position of the hyoid body. None of the body size characters had any impact on hyoid asymmetry. Ultimately, sexually dimorphic variation was revealed for age-dependent changes in both size and shape of hyoid bones as male hyoids tend to be more susceptible to modifications with age than female bones. Copyright © 2013 Elsevier GmbH. All rights reserved.

Novel joint TOA/RSSI-based WCE location tracking method without prior knowledge of biological human body tissues.

PubMed

Ito, Takahiro; Anzai, Daisuke; Jianqing Wang

2014-01-01

This paper proposes a novel joint time of arrival (TOA)/received signal strength indicator (RSSI)-based wireless capsule endoscope (WCE) location tracking method without prior knowledge of biological human tissues. Generally, TOA-based localization can achieve much higher localization accuracy than other radio frequency-based localization techniques, whereas wireless signals transmitted from a WCE pass through various kinds of human body tissues, as a result, the propagation velocity inside a human body should be different from one in free space. Because the variation of propagation velocity is mainly affected by the relative permittivity of human body tissues, instead of pre-measurement for the relative permittivity in advance, we simultaneously estimate not only the WCE location but also the relative permittivity information. For this purpose, this paper first derives the relative permittivity estimation model with measured RSSI information. Then, we pay attention to a particle filter algorithm with the TOA-based localization and the RSSI-based relative permittivity estimation. Our computer simulation results demonstrates that the proposed tracking methods with the particle filter can accomplish an excellent localization accuracy of around 2 mm without prior information of the relative permittivity of the human body tissues.

Daily dietary selenium intake and hair selenium content in a high selenium area of Enshi, China

USDA-ARS?s Scientific Manuscript database

Selenium is essential to humans and is widely distributed within the human body. Its content in blood, urine, hair and nails are important indicators to evaluate Se level in the human body. In China (Shadi, Enschi city), human selenosis of residents is reported to occur in high numbers. In this stud...

Biophoton emission of human body.

PubMed

Cohen, S; Popp, F A

2003-05-01

For the first time systematic measurements of the "ultraweak" photon emission of the human body (biophotons) have been performed by means of a photon detector device set up in darkness. About 200 persons have been investigated. In a particular case one person has been examined daily over several months. It turned out that this biophoton emission reflects, (i) the left-right symmetry of the human body; (ii) biological rhythms such as 14 days, 1 month, 3 months and 9 months; (iii) disease in terms of broken symmetry between left and right side; and (iv) light channels in the body, which regulate energy and information transfer between different parts. The results show that besides a deeper understanding of health, disease and body field, this method provides a new powerful tool of non-invasive medical diagnosis in terms of basic regulatory functions of the body.

A Comparison of Averaged and Full Models to Study the Third-Body Perturbation

PubMed Central

Solórzano, Carlos Renato Huaura; Prado, Antonio Fernando Bertachini de Almeida

2013-01-01

The effects of a third-body travelling in a circular orbit around a main body on a massless satellite that is orbiting the same main body are studied under two averaged models, single and double, where expansions of the disturbing function are made, and the full restricted circular three-body problem. The goal is to compare the behavior of these two averaged models against the full problem for long-term effects, in order to have some knowledge of their differences. The single averaged model eliminates the terms due to the short period of the spacecraft. The double average is taken over the mean motion of the satellite and the mean motion of the disturbing body, so removing both short period terms. As an example of the methods, an artificial satellite around the Earth perturbed by the Moon is used. A detailed study of the effects of different initial conditions in the orbit of the spacecraft is made. PMID:24319348

A comparison of averaged and full models to study the third-body perturbation.

PubMed

Solórzano, Carlos Renato Huaura; Prado, Antonio Fernando Bertachini de Almeida

2013-01-01

The effects of a third-body travelling in a circular orbit around a main body on a massless satellite that is orbiting the same main body are studied under two averaged models, single and double, where expansions of the disturbing function are made, and the full restricted circular three-body problem. The goal is to compare the behavior of these two averaged models against the full problem for long-term effects, in order to have some knowledge of their differences. The single averaged model eliminates the terms due to the short period of the spacecraft. The double average is taken over the mean motion of the satellite and the mean motion of the disturbing body, so removing both short period terms. As an example of the methods, an artificial satellite around the Earth perturbed by the Moon is used. A detailed study of the effects of different initial conditions in the orbit of the spacecraft is made.

Does Human Milk Modulate Body Composition in Late Preterm Infants at Term-Corrected Age?

PubMed

Giannì, Maria Lorella; Consonni, Dario; Liotto, Nadia; Roggero, Paola; Morlacchi, Laura; Piemontese, Pasqua; Menis, Camilla; Mosca, Fabio

2016-10-23

(1) Background: Late preterm infants account for the majority of preterm births and are at risk of altered body composition. Because body composition modulates later health outcomes and human milk is recommended as the normal method for infant feeding, we sought to investigate whether human milk feeding in early life can modulate body composition development in late preterm infants; (2) Methods: Neonatal, anthropometric and feeding data of 284 late preterm infants were collected. Body composition was evaluated at term-corrected age by air displacement plethysmography. The effect of human milk feeding on fat-free mass and fat mass content was evaluated using multiple linear regression analysis; (3) Results: Human milk was fed to 68% of the infants. According to multiple regression analysis, being fed any human milk at discharge and at  term-corrected and being fed exclusively human milk at term-corrected age were positively associated with fat-free mass content(β = -47.9, 95% confidence interval (CI) = -95.7; -0.18; p = 0.049; β = -89.6, 95% CI = -131.5; -47.7; p < 0.0001; β = -104.1, 95% CI = -151.4; -56.7, p < 0.0001); (4) Conclusion: Human milk feeding appears to be associated with fat-free mass deposition in late preterm infants. Healthcare professionals should direct efforts toward promoting and supporting breastfeeding in these vulnerable infants.

Robotic Reconnaissance Missions to Small Bodies and Their Potential Contributions to Human Exploration

NASA Technical Reports Server (NTRS)

Abell, P. A.; Rivkin, A. S.

2015-01-01

Introduction: Robotic reconnaissance missions to small bodies will directly address aspects of NASA's Asteroid Initiative and will contribute to future human exploration. The NASA Asteroid Initiative is comprised of two major components: the Grand Challenge and the Asteroid Mission. The first component, the Grand Challenge, focuses on protecting Earth's population from asteroid impacts by detecting potentially hazardous objects with enough warning time to either prevent them from impacting the planet, or to implement civil defense procedures. The Asteroid Mission involves sending astronauts to study and sample a near- Earth asteroid (NEA) prior to conducting exploration missions of the Martian system, which includes Phobos and Deimos. The science and technical data obtained from robotic precursor missions that investigate the surface and interior physical characteristics of an object will help identify the pertinent physical properties that will maximize operational efficiency and reduce mission risk for both robotic assets and crew operating in close proximity to, or at the surface of, a small body. These data will help fill crucial strategic knowledge gaps (SKGs) concerning asteroid physical characteristics that are relevant for human exploration considerations at similar small body destinations. Small Body Strategic Knowledge Gaps: For the past several years NASA has been interested in identifying the key SKGs related to future human destinations. These SKGs highlight the various unknowns and/or data gaps of targets that the science and engineering communities would like to have filled in prior to committing crews to explore the Solar System. An action team from the Small Bodies Assessment Group (SBAG) was formed specifically to identify the small body SKGs under the direction of the Human Exploration and Operations Missions Directorate (HEOMD), given NASA's recent interest in NEAs and the Martian moons as potential human destinations [1]. The action team organized the SKGs into four broad themes: 1) Identify human mission targets; 2) Understand how to work on and interact with the small body surface; 3) Understand the small body environment and its potential risk/benefit to crew, systems, and operational assets; and 4) Understand the small body resource potential. Each of these themes were then further subdivided into categories to address specific SKG issues. Robotic Precursor Contributions to SKGs: Robotic reconnaissance missions should be able to address specific aspects related to SKG themes 1 through 4. Theme 1 deals with the identification of human mission targets within the NEA population. The current guideline indicates that human missions to fastspinning, tumbling, or binary asteroids may be too risky to conduct successfully from an operational perspective. However, no spacecraft mission has been to any of these types of NEAs before. Theme 2 addresses the concerns about interacting on the small body surface under microgravity conditions, and how the surface and/or sub-surface properties affect or restrict the interaction for human exploration. The combination of remote sensing instruments and in situ payloads will provide good insight into the asteroid's surface and subsurface properties. SKG theme 3 deals with the environment in and around the small body that may present a nuisance or hazard to any assets operating in close proximity. Impact and surface experiments will help address issues related to particle size, particle longevity, internal structure, and the near-surface mechanical stability of the asteroid. Understanding or constraining these physical characteristics are important for mission planning. Theme 4 addresses the resource potential of the small body. This is a particularly important aspect of human exploration since the identification and utilization of resources is a key aspect for deep space mission architectures to the Martian system (i.e., Phobos and Deimos). Conclusions: Robotic reconnaissance of small bodies can provide a wealth of information relevant to the science and planetary defense of NEAs. However, such missions to investigate NEAs can also provide key insights into small body strategic knowledge gaps and contribute to the overall success for human exploration missions to asteroids.

16 CFR 453.1 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-01-01

... deceased human bodies for burial, cremation or other final disposition; and (2) arrange, supervise or conduct the funeral ceremony or the final disposition of deceased human bodies. (k) Immediate burial. An... enclosure, without ornamentation or a fixed interior lining, which is designed for the encasement of human...

16 CFR 453.1 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-01-01

... deceased human bodies for burial, cremation or other final disposition; and (2) arrange, supervise or conduct the funeral ceremony or the final disposition of deceased human bodies. (k) Immediate burial. An... enclosure, without ornamentation or a fixed interior lining, which is designed for the encasement of human...

16 CFR 453.1 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-01-01

... deceased human bodies for burial, cremation or other final disposition; and (2) arrange, supervise or conduct the funeral ceremony or the final disposition of deceased human bodies. (k) Immediate burial. An... enclosure, without ornamentation or a fixed interior lining, which is designed for the encasement of human...

16 CFR 453.1 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... deceased human bodies for burial, cremation or other final disposition; and (2) arrange, supervise or conduct the funeral ceremony or the final disposition of deceased human bodies. (k) Immediate burial. An... enclosure, without ornamentation or a fixed interior lining, which is designed for the encasement of human...

16 CFR 453.1 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... deceased human bodies for burial, cremation or other final disposition; and (2) arrange, supervise or conduct the funeral ceremony or the final disposition of deceased human bodies. (k) Immediate burial. An... enclosure, without ornamentation or a fixed interior lining, which is designed for the encasement of human...

Simple electrical model and initial experiments for intra-body communications.

PubMed

Gao, Y M; Pun, S H; Du, M; Mak, P U; Vai, M I

2009-01-01

Intra-Body Communication(IBC) is a short range "wireless" communication technique appeared in recent years. This technique relies on the conductive property of human tissue to transmit the electric signal among human body. This is beneficial for devices networking and sensors among human body, and especially suitable for wearable sensors, telemedicine system and home health care system as in general the data rates of physiologic parameters are low. In this article, galvanic coupling type IBC application on human limb was investigated in both its mathematical model and related experiments. The experimental results showed that the proposed mathematical model was capable in describing the galvanic coupling type IBC under low frequency. Additionally, the calculated result and experimental result also indicated that the electric signal induced by the transmitters of IBC can penetrate deep into human muscle and thus, provide an evident that IBC is capable of acting as networking technique for implantable devices.

[Lice and lice-borne diseases in humans].

PubMed

Houhamdi, L; Parola, P; Raoult, D

2005-01-01

Among the three lice which parasite the human being, the human body louse, Pediculus humanus humanus, is a vector of infectious diseases. It lives and multiplies in clothes and human infestation is associated with cold weather and a lack of hygiene. Three pathogenic bacteria are transmitted by the body louse: 1) Rickettsia prowazekii, the agent of epidemic typhus of which the most recent outbreak (and the largest since World War II) was observed during the civil war in Burundi; 2) Borrelia recurrentis, the agent of relapsing fever, historically responsible of massive outbreaks in Eurasia and Africa, which prevails currently in Ethiopia and neighboring countries; 3) Bartonella quintana, the agent of trench fever, bacillary angiomatosis, chronic bacteremia, endocarditis, and lymphadenopathy. Body louse infestation, associated with a decline in social and hygienic conditions provoked by civil unrest and economic instability, is reemergent worldwide. Recently, a forth human pathogen, Acinetobacter baumannii, has been associated to the body louse.

The Research of Computer Aided Farm Machinery Designing Method Based on Ergonomics

NASA Astrophysics Data System (ADS)

Gao, Xiyin; Li, Xinling; Song, Qiang; Zheng, Ying

Along with agricultural economy development, the farm machinery product type Increases gradually, the ergonomics question is also getting more and more prominent. The widespread application of computer aided machinery design makes it possible that farm machinery design is intuitive, flexible and convenient. At present, because the developed computer aided ergonomics software has not suitable human body database, which is needed in view of farm machinery design in China, the farm machinery design have deviation in ergonomics analysis. This article puts forward that using the open database interface procedure in CATIA to establish human body database which aims at the farm machinery design, and reading the human body data to ergonomics module of CATIA can product practical application virtual body, using human posture analysis and human activity analysis module to analysis the ergonomics in farm machinery, thus computer aided farm machinery designing method based on engineering can be realized.

The public display of plastinates as a challenge to the integrity of anatomy.

PubMed

Jones, David Gareth

2016-01-01

Anatomy has been thrust into the public domain by the highly successful public displays of dissected and plastinated human bodies. This is anatomy in modern guise, anatomy as perceived by the general public. If this is the case, the message it is giving the public about the nature of anatomy is that it is an impersonal analysis of the human body of value within a medical and health care environment. While this is in part true, and while it reflects important aspects of anatomy's history, it fails to reflect the humanistic strands within an increasing swathe of contemporary anatomy. These are manifested in growing recognition of the centrality of informed consent in the practice of anatomy, awareness of the personal dimensions and relationships of those whose bodies are being dissected, and manifested in thanksgiving ceremonies involving staff and students. The notion that the bodies undergoing dissection can be students' first teachers and/or patients is gaining ground, another indication of the human dimensions of the anatomical enterprise. Exhibitions such as Body Worlds ignore these dimensions within anatomy by dislocating it from its clinical and relational base. The significance of this is that loss of these dimensions leads to a loss of the human face of anatomy by isolating it from the people whose body bequests made this knowledge possible. What is required is greater transparency and openness in the practices of all who deal with the dead human body, trends that owe much to the writings of scholars from within a range of humanities disciplines as they have responded to the public displays of dissected plastinated bodies. Anatomists have much to learn from these debates. © 2015 Wiley Periodicals, Inc.

An analytic model of the in-line and cross-axis apparent mass of the seated human body exposed to vertical vibration with and without a backrest

NASA Astrophysics Data System (ADS)

Zheng, Guangtai; Qiu, Yi; Griffin, Michael J.

2011-12-01

During vertical excitation of the seated human body there are vertical and fore-and-aft forces at the seat that are influenced by contact with a backrest, so it is desirable to take into account the effect of a backrest when developing models of the seated human body. Initially, a seven degree-of-freedom multi-body dynamic model was developed for the human body sitting with an upright posture unsupported by a backrest and exposed to vertical vibration. The model was optimized to fit the vertical apparent mass and the fore-and-aft cross-axis apparent mass measured on a seat. The model was then extended by the addition of vertical and fore-and-aft reaction forces to the upper lumbar spine to model the interaction between the human body and a backrest. By minimizing the least square error between experimental data and the analytical solution of the apparent masses on the seat and at the back, the human body model was able to represent both the vertical apparent mass and the fore-and-aft cross-axis apparent mass on the seat and at the back. Parameter sensitivity studies showed that the vertical apparent mass and the fore-and-aft cross-axis apparent mass on the seat and the backrest were all highly sensitive to the axial stiffness of the tissue beneath the pelvis. Pitch motion of the upper-body contributed to the vertical apparent mass and the fore-and-aft cross-axis apparent mass on the seat. The apparent mass at the back was more sensitive to the stiffness and damping of the lower back than the properties of the upper back.

Hierarchical parsing and semantic navigation of full body CT data

NASA Astrophysics Data System (ADS)

Seifert, Sascha; Barbu, Adrian; Zhou, S. Kevin; Liu, David; Feulner, Johannes; Huber, Martin; Suehling, Michael; Cavallaro, Alexander; Comaniciu, Dorin

2009-02-01

Whole body CT scanning is a common diagnosis technique for discovering early signs of metastasis or for differential diagnosis. Automatic parsing and segmentation of multiple organs and semantic navigation inside the body can help the clinician in efficiently obtaining accurate diagnosis. However, dealing with the large amount of data of a full body scan is challenging and techniques are needed for the fast detection and segmentation of organs, e.g., heart, liver, kidneys, bladder, prostate, and spleen, and body landmarks, e.g., bronchial bifurcation, coccyx tip, sternum, lung tips. Solving the problem becomes even more challenging if partial body scans are used, where not all organs are present. We propose a new approach to this problem, in which a network of 1D and 3D landmarks is trained to quickly parse the 3D CT data and estimate which organs and landmarks are present as well as their most probable locations and boundaries. Using this approach, the segmentation of seven organs and detection of 19 body landmarks can be obtained in about 20 seconds with state-of-the-art accuracy and has been validated on 80 CT full or partial body scans.

Steady-state visually evoked potential correlates of human body perception.

PubMed

Giabbiconi, Claire-Marie; Jurilj, Verena; Gruber, Thomas; Vocks, Silja

2016-11-01

In cognitive neuroscience, interest in the neuronal basis underlying the processing of human bodies is steadily increasing. Based on functional magnetic resonance imaging studies, it is assumed that the processing of pictures of human bodies is anchored in a network of specialized brain areas comprising the extrastriate and the fusiform body area (EBA, FBA). An alternative to examine the dynamics within these networks is electroencephalography, more specifically so-called steady-state visually evoked potentials (SSVEPs). In SSVEP tasks, a visual stimulus is presented repetitively at a predefined flickering rate and typically elicits a continuous oscillatory brain response at this frequency. This brain response is characterized by an excellent signal-to-noise ratio-a major advantage for source reconstructions. The main goal of present study was to demonstrate the feasibility of this method to study human body perception. To that end, we presented pictures of bodies and contrasted the resulting SSVEPs to two control conditions, i.e., non-objects and pictures of everyday objects (chairs). We found specific SSVEPs amplitude differences between bodies and both control conditions. Source reconstructions localized the SSVEP generators to a network of temporal, occipital and parietal areas. Interestingly, only body perception resulted in activity differences in middle temporal and lateral occipitotemporal areas, most likely reflecting the EBA/FBA.

Leptin, the ob gene product, in female health and disease.

PubMed

Schubring, C; Blum, W F; Kratzsch, J; Deutscher, J; Kiess, W

2000-02-01

Leptin is a recently discovered hormone which is involved in the regulation of body weight. It provides a molecular basis for the lipostatic theory of the regulation of energy balance. White adipose tissue is the main site of leptin synthesis and there is some evidence of ob gene expression in brown fat. Leptin seems to play a key role in the control of body fat stores by coordinated regulation of feeding behaviour, metabolic rate, autonomic nervous system regulation and body energy balance in rodents, primates and humans. Apart from the function of leptin in the central nervous system on the regulation of energy balance, it may well be one of the hormonal factors that signal the body's readiness for sexual maturation and reproduction to the brain. During late pregnancy and at birth when maternal fat stores have been developed leptin levels are high. Leptin could then be a messenger molecule signaling the adequacy of the fat stores for reproduction and maintenance of pregnancy. At later stages of gestation leptin could signal the expansion of fat stores in order to prepare the expectant mother for the energy requirements of full term gestation, labour and lactation. This overview focuses on those topics of leptin research which are of particular interest in reproductive medicine and gynecology.

[Human, transhuman, posthuman. Representations of the body between incompleteness and enhancement].

PubMed

Maestrutti, Marina

2011-01-01

"Posthuman" is often used to indicate some position, practice, perspective and vision concerning the future of human beings closely related to the use of contemporary technologies. This contribution would like to analyze some conceptions of the notion of posthuman and to present it as a possible form of "non-anthropocentric" thought which considers technological changes as non-human realities strictly involved in the construction and the definition of what constitutes a human being (and his body) and its predicates. Contrary to anthropocentrism which has characterized Western thought from humanism up to the extreme outcomes of transhumanism, non-anthropocentric posthumanism shows how the human being, who has always been the product of hybridization with the non-human (environment, animals and techniques), is built not only by his own strength but always through his partnership and his environment. The idea of enhancement of the body by technology to reach another stage of human evolution is one of the constant elements characterizing transhumanism. Posthumanism suggests no longer considering the interface with technology as an ergonomic relationship with an external tool that just extends the human body, but as a hybrid, or interpenetration that questions the separation of the body and its centrality. In this perspective, the question is not of simply establishing which is a good use of a technology but, every time, of redefining ourselves in our perspectives and our predicates with regard to what a technology allows and opens up to us.

State-of-the-art measurements in human body composition: A moving frontier of clinical importance.

PubMed

Gallagher, D; Shaheen, I; Zafar, K

2008-01-01

The measurement of human body composition allows for the estimation of body tissues, organs, and their distributions in living persons without inflicting harm. From a nutritional perspective, the interest in body composition has increased multi-fold with the global increase in the prevalence of obesity and its complications. The latter has driven in part the need for improved measurement methods with greater sensitivity and precision. There is no single gold standard for body-composition measurements in-vivo. All methods incorporate assumptions that do not apply in all individuals and the more accurate models are derived by using a combination of measurements, thereby reducing the importance of each assumption. This review will discuss why the measurement of body composition or human phenotyping is important; discuss new areas where the measurement of body composition (human phenotyping) is recognized as having important application; and will summarize recent advances made in new methodology. Reference will also be made to areas we cannot yet measure due to the lack of appropriate measurement methodologies, most especially measurements methods that provide information on kinetic states (not just static state) and metabolic function.

Metabolic rate M  0.75 in human beings

NASA Astrophysics Data System (ADS)

Agrawal, D. C.

2014-11-01

Human beings consume energy every day. Even at rest, energy is still needed for the working of the internal organs. This is achieved by the metabolism of consumed food in the presence of inhaled oxygen. During the resting state this is called the maintenance rate, and follows the mouse-to-elephant formula, Pmet = 70M0.75 kcal per day. Here, M is the body mass of the subject in kilograms. The heat generated in metabolism is lost through the body surface of the subject, so the metabolic rate should also be proportional to the body surface area. In other words, the body surface area in the case of a human being must also depend on M0.75. The present paper examines this issue by finding a relationship between human body surface area and its mass through a very simple model that can be easily understood and verified by physics students, who can also compare it with all the expressions for body surface area available in the literature. This will build confidence in the students that the heat generated from metabolism in fact dissipates through the surface of the body.

State-of-the-art measurements in human body composition: A moving frontier of clinical importance

PubMed Central

Gallagher, D.; Shaheen, I.; Zafar, K.

2010-01-01

The measurement of human body composition allows for the estimation of body tissues, organs, and their distributions in living persons without inflicting harm. From a nutritional perspective, the interest in body composition has increased multi-fold with the global increase in the prevalence of obesity and its complications. The latter has driven in part the need for improved measurement methods with greater sensitivity and precision. There is no single gold standard for body-composition measurements in-vivo. All methods incorporate assumptions that do not apply in all individuals and the more accurate models are derived by using a combination of measurements, thereby reducing the importance of each assumption. This review will discuss why the measurement of body composition or human phenotyping is important; discuss new areas where the measurement of body composition (human phenotyping) is recognized as having important application; and will summarize recent advances made in new methodology. Reference will also be made to areas we cannot yet measure due to the lack of appropriate measurement methodologies, most especially measurements methods that provide information on kinetic states (not just static state) and metabolic function. PMID:21234275

Human location estimation using thermopile array sensor

NASA Astrophysics Data System (ADS)

Parnin, S.; Rahman, M. M.

2017-11-01

Utilization of Thermopile sensor at an early stage of human detection is challenging as there are many things that produce thermal heat other than human such as electrical appliances and animals. Therefrom, an algorithm for early presence detection has been developed through the study of human body temperature behaviour with respect to the room temperature. The change in non-contact detected temperature of human varied according to body parts. In an indoor room, upper parts of human body change up to 3°C whereas lower part ranging from 0.58°C to 1.71°C. The average changes in temperature of human is used as a conditional set-point value in the program algorithm to detect human presence. The current position of human and its respective angle is gained when human is presence at certain pixels of Thermopile’s sensor array. Human position is estimated successfully as the developed sensory system is tested to the actuator of a stand fan.

AC Electric Field Communication for Human-Area Networking

NASA Astrophysics Data System (ADS)

Kado, Yuichi; Shinagawa, Mitsuru

We have proposed a human-area networking technology that uses the surface of the human body as a data transmission path and uses an AC electric field signal below the resonant frequency of the human body. This technology aims to achieve a “touch and connect” intuitive form of communication by using the electric field signal that propagates along the surface of the human body, while suppressing both the electric field radiating from the human body and mutual interference. To suppress the radiation field, the frequency of the AC signal that excites the transmitter electrode must be lowered, and the sensitivity of the receiver must be raised while reducing transmission power to its minimally required level. We describe how we are developing AC electric field communication technologies to promote the further evolution of a human-area network in support of ubiquitous services, focusing on three main characteristics, enabling-transceiver technique, application-scenario modeling, and communications quality evaluation. Special attention is paid to the relationship between electro-magnetic compatibility evaluation and regulations for extremely low-power radio stations based on Japan's Radio Law.

Sex differences in chronometric mental rotation with human bodies.

PubMed

Voyer, Daniel; Jansen, Petra

2016-11-01

The present experiment investigated sex differences across stimulus types in a chronometric mental rotation task. The working hypothesis was that human bodies as stimuli would reduce the magnitude of sex differences compared to cubes as stimuli, from the embodied cognition perspective. One hundred and twenty participants, 60 men and 60 women solved chronometric mental rotation items with Shepard-Metzler cube figures, head-cubes, and human bodies, all designed so that they were similar in shape. Two figures of a given stimulus type were presented on the screen and participants had to judge if both items were mirrored or non-mirrored. Results showed better mental rotation performance with human bodies than with other types of stimuli for both sexes, although the effect of stimulus type was more pronounced in men than in women. Furthermore, regardless of stimulus type, men were more accurate than women. Altogether, the results suggest that sex differences are not reduced when human bodies are used as stimuli in a chronometric task. Implications for accounts of sex differences in mental rotations are discussed.

New equivalent-electrical circuit model and a practical measurement method for human body impedance.

PubMed

Chinen, Koyu; Kinjo, Ichiko; Zamami, Aki; Irei, Kotoyo; Nagayama, Kanako

2015-01-01

Human body impedance analysis is an effective tool to extract electrical information from tissues in the human body. This paper presents a new measurement method of impedance using armpit electrode and a new equivalent circuit model for the human body. The lowest impedance was measured by using an LCR meter and six electrodes including armpit electrodes. The electrical equivalent circuit model for the cell consists of resistance R and capacitance C. The R represents electrical resistance of the liquid of the inside and outside of the cell, and the C represents high frequency conductance of the cell membrane. We propose an equivalent circuit model which consists of five parallel high frequency-passing CR circuits. The proposed equivalent circuit represents alpha distribution in the impedance measured at a lower frequency range due to ion current of the outside of the cell, and beta distribution at a high frequency range due to the cell membrane and the liquid inside cell. The calculated values by using the proposed equivalent circuit model were consistent with the measured values for the human body impedance.

Can we colonize the solar system? Human biology and survival in the extreme space environment.

PubMed

Launius, Roger D

2010-09-01

Throughout the history of the space age the dominant vision for the future has been great spaceships plying the solar system, and perhaps beyond, moving living beings from one planet to another. Spacesuited astronauts would carry out exploration, colonization, and settlement as part of a relentlessly forward looking movement of humanity beyond Earth. As time has progressed this image has not changed appreciably even as the full magnitude of the challenges it represents have become more and more apparent. This essay explores the issues associated with the human movement beyond Earth and raises questions about whether humanity will ever be able to survive in the extreme environment of space and the other bodies of the solar system. This paper deals with important historical episodes as well as wider conceptual issues about life in space. Two models of expansion beyond Earth are discussed: (1) the movement of microbes and other types of life on Earth that can survive the space environment and (2) the modification of humans into cyborgs for greater capability to survive in the extreme environments encountered beyond this planet. (c) 2010 Elsevier Ltd. All rights reserved.

Dissociable neural responses to hands and non-hand body parts in human left extrastriate visual cortex.

PubMed

Bracci, Stefania; Ietswaart, Magdalena; Peelen, Marius V; Cavina-Pratesi, Cristiana

2010-06-01

Accumulating evidence points to a map of visual regions encoding specific categories of objects. For example, a region in the human extrastriate visual cortex, the extrastriate body area (EBA), has been implicated in the visual processing of bodies and body parts. Although in the monkey, neurons selective for hands have been reported, in humans it is unclear whether areas selective for individual body parts such as the hand exist. Here, we conducted two functional MRI experiments to test for hand-preferring responses in the human extrastriate visual cortex. We found evidence for a hand-preferring region in left lateral occipitotemporal cortex in all 14 participants. This region, located in the lateral occipital sulcus, partially overlapped with left EBA, but could be functionally and anatomically dissociated from it. In experiment 2, we further investigated the functional profile of hand- and body-preferring regions by measuring responses to hands, fingers, feet, assorted body parts (arms, legs, torsos), and non-biological handlike stimuli such as robotic hands. The hand-preferring region responded most strongly to hands, followed by robotic hands, fingers, and feet, whereas its response to assorted body parts did not significantly differ from baseline. By contrast, EBA responded most strongly to body parts, followed by hands and feet, and did not significantly respond to robotic hands or fingers. Together, these results provide evidence for a representation of the hand in extrastriate visual cortex that is distinct from the representation of other body parts.

Dissociable Neural Responses to Hands and Non-Hand Body Parts in Human Left Extrastriate Visual Cortex

PubMed Central

Ietswaart, Magdalena; Peelen, Marius V.; Cavina-Pratesi, Cristiana

2010-01-01

Accumulating evidence points to a map of visual regions encoding specific categories of objects. For example, a region in the human extrastriate visual cortex, the extrastriate body area (EBA), has been implicated in the visual processing of bodies and body parts. Although in the monkey, neurons selective for hands have been reported, in humans it is unclear whether areas selective for individual body parts such as the hand exist. Here, we conducted two functional MRI experiments to test for hand-preferring responses in the human extrastriate visual cortex. We found evidence for a hand-preferring region in left lateral occipitotemporal cortex in all 14 participants. This region, located in the lateral occipital sulcus, partially overlapped with left EBA, but could be functionally and anatomically dissociated from it. In experiment 2, we further investigated the functional profile of hand- and body-preferring regions by measuring responses to hands, fingers, feet, assorted body parts (arms, legs, torsos), and non-biological handlike stimuli such as robotic hands. The hand-preferring region responded most strongly to hands, followed by robotic hands, fingers, and feet, whereas its response to assorted body parts did not significantly differ from baseline. By contrast, EBA responded most strongly to body parts, followed by hands and feet, and did not significantly respond to robotic hands or fingers. Together, these results provide evidence for a representation of the hand in extrastriate visual cortex that is distinct from the representation of other body parts. PMID:20393066

NIH Human Microbiome Project defines normal bacterial makeup of the body

Cancer.gov

Microbes inhabit just about every part of the human body, living on the skin, in the gut, and up the nose. Sometimes they cause sickness, but most of the time, microorganisms live in harmony with their human hosts, providing vital functions essential for

Genes

MedlinePlus

... the human body. Together, they make up the blueprint for the human body and how it works. ... this important distinction for online health information and services. Learn more about A.D.A.M.'s editorial ...

Acinetobacter baumannii in Human Body Louse

PubMed Central

Raoult, Didier

2004-01-01

While we were isolating Bartonella quintana from body lice, 40 Acinetobacter baumannii strains were also isolated and genotyped. One clone was unique and the other was ampicillin susceptible. A. baumannii DNA was later detected in 21% of 622 lice collected worldwide. These findings show an A. baumannii epidemic in human body lice. PMID:15498175

Formal Body Bequest Program in Nigerian Medical Schools: When Do We Start?

ERIC Educational Resources Information Center

Akinola, Oluwole Busayo

2011-01-01

Human body dissection is a prerequisite for the training of health professionals and the conduct of medical research. However, most Nigerian medical schools experience difficulty obtaining an adequate and regular supply of human tissue. Presently, the major source of anatomical material comes from unclaimed bodies collected from hospital…

Re-Educating the Body

ERIC Educational Resources Information Center

Holst, Jonas

2013-01-01

This article means to investigate the philosophical concept of human embodiment in relation to physical education. As human beings not only do we have a body that we can control, but we "are" our body and live embodied in the world, as the German thinker, Helmuth Plessner, puts it in one of his many contributions to the philosophical…

Imaging methods for analyzing body composition in human obesity and cardiometabolic disease.

PubMed

Seabolt, Lynn A; Welch, E Brian; Silver, Heidi J

2015-09-01

Advances in the technological qualities of imaging modalities for assessing human body composition have been stimulated by accumulating evidence that individual components of body composition have significant influences on chronic disease onset, disease progression, treatment response, and health outcomes. Importantly, imaging modalities have provided a systematic method for differentiating phenotypes of body composition that diverge from what is considered normal, that is, having low bone mass (osteopenia/osteoporosis), low muscle mass (sarcopenia), high fat mass (obesity), or high fat with low muscle mass (sarcopenic obesity). Moreover, advances over the past three decades in the sensitivity and quality of imaging not just to discern the amount and distribution of adipose and lean tissue but also to differentiate layers or depots within tissues and cells is enhancing our understanding of distinct mechanistic, metabolic, and functional roles of body composition within human phenotypes. In this review, we focus on advances in imaging technologies that show great promise for future investigation of human body composition and how they are being used to address the pandemic of obesity, metabolic syndrome, and diabetes. © 2015 New York Academy of Sciences.

Modelling accidental hypothermia effects on a human body under different pathophysiological conditions.

PubMed

Coccarelli, Alberto; Boileau, Etienne; Parthimos, Dimitris; Nithiarasu, Perumal

2017-12-01

Accidental exposure to cold water environment is one of the most challenging situations in which hypothermia occurs. In the present work, we aim to characterise the energy balance of a human body subjected to such extreme environmental conditions. This study is carried out using a recently developed computational model and by setting boundary conditions needed to simulate the effect of cold surrounding environment. A major finding is the capacity of the body core regions to maintain their temperature high for a substantial amount of time, even under the most extreme environmental conditions. We also considered two disease states that highlight the spectrum of possible pathologies implicated in thermal regulation of the human body. These states are (i) cardiomyopathy, which affects the operating capacity of the heart, and (ii) malnutrition, which directly impairs the body's ability to regulate heat exchange with the environment. We have found that cardiomyopathy has little influence on the thermal balance of the human body, whereas malnutrition has a profound negative effect on the thermal balance and leads to dramatic reduction in core temperature.

Human and animal sounds influence recognition of body language.

PubMed

Van den Stock, Jan; Grèzes, Julie; de Gelder, Beatrice

2008-11-25

In naturalistic settings emotional events have multiple correlates and are simultaneously perceived by several sensory systems. Recent studies have shown that recognition of facial expressions is biased towards the emotion expressed by a simultaneously presented emotional expression in the voice even if attention is directed to the face only. So far, no study examined whether this phenomenon also applies to whole body expressions, although there is no obvious reason why this crossmodal influence would be specific for faces. Here we investigated whether perception of emotions expressed in whole body movements is influenced by affective information provided by human and by animal vocalizations. Participants were instructed to attend to the action displayed by the body and to categorize the expressed emotion. The results indicate that recognition of body language is biased towards the emotion expressed by the simultaneously presented auditory information, whether it consist of human or of animal sounds. Our results show that a crossmodal influence from auditory to visual emotional information obtains for whole body video images with the facial expression blanked and includes human as well as animal sounds.

Detection of Acinetobacter baumannii in human head and body lice from Ethiopia and identification of new genotypes.

PubMed

Kempf, Marie; Abdissa, Alemseged; Diatta, Georges; Trape, Jean-François; Angelakis, Emmanouil; Mediannikov, Oleg; La Scola, Bernard; Raoult, Didier

2012-09-01

Acinetobacter baumannii has previously been detected and genotyped in human body lice. The objectives of this study were to determine the presence of this bacterium in head and body lice collected from healthy individuals in Ethiopia by molecular methods and to characterize the genotype. Human lice from locations at different altitudes in Ethiopia were screened for the presence of Acinetobacter sp by targeting the rpoB gene. Acinetobacter baumannii was detected and genotyped using recA PCR amplification. A total of 115 head and 109 body lice were collected from 134 healthy individuals. Acinetobacter sp were found in 54 head (47%) and 77 body (71%) lice. The recA gene was sequenced for 60 of the Acinetobacter sp and 67% were positive for A. baumannii; genotype 1 was retrieved the most frequently. Our study is the first to show the presence of A. baumannii in human body lice, and also in head lice, in Ethiopia. Copyright © 2012 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

Height and body mass influence on human body outlines: a quantitative approach using an elliptic Fourier analysis.

PubMed

Courtiol, Alexandre; Ferdy, Jean Baptiste; Godelle, Bernard; Raymond, Michel; Claude, Julien

2010-05-01

Many studies use representations of human body outlines to study how individual characteristics, such as height and body mass, affect perception of body shape. These typically involve reality-based stimuli (e.g., pictures) or manipulated stimuli (e.g., drawings). These two classes of stimuli have important drawbacks that limit result interpretations. Realistic stimuli vary in terms of traits that are correlated, which makes it impossible to assess the effect of a single trait independently. In addition, manipulated stimuli usually do not represent realistic morphologies. We describe and examine a method based on elliptic Fourier descriptors to automatically predict and represent body outlines for a given set of predicted variables (e.g., sex, height, and body mass). We first estimate whether these predictive variables are significantly related to human outlines. We find that height and body mass significantly influence body shape. Unlike height, the effect of body mass on shape differs between sexes. Then, we show that we can easily build a regression model that creates hypothetical outlines for an arbitrary set of covariates. These statistically computed outlines are quite realistic and may be used as stimuli in future studies.

Human body odour, symmetry and attractiveness.

PubMed Central

Rikowski, A; Grammer, K

1999-01-01

Several studies have found body and facial symmetry as well as attractiveness to be human mate choice criteria. These characteristics are presumed to signal developmental stability. Human body odour has been shown to influence female mate choice depending on the immune system, but the question of whether smell could signal general mate quality, as do other cues, was not addressed in previous studies. We compared ratings of body odour, attractiveness, and measurements of facial and body asymmetry of 16 male and 19 female subjects. Subjects wore a T-shirt for three consecutive nights under controlled conditions. Opposite-sex raters judged the odour of the T-shirts and another group evaluated portraits of the subjects for attractiveness. We measured seven bilateral traits of the subject's body to assess body asymmetry. Facial asymmetry was examined by distance measurements of portrait photographs. The results showed a significant positive correlation between facial attractiveness and sexiness of body odour for female subjects. We found positive relationships between body odour and attractiveness and negative ones between smell and body asymmetry for males only if female odour raters were in the most fertile phase of their menstrual cycle. The outcomes are discussed in the light of different male and female reproductive strategies. PMID:10380676

A study on transmission characteristics and specific absorption rate using impedance-matched electrodes for various human body communication.

PubMed

Machida, Yuta; Yamamoto, Takahiko; Koshiji, Kohji

2013-01-01

Human body communication (HBC) is a new communication technology that has presented potential applications in health care and elderly support systems in recent years. In this study, which is focused on a wearable transmitter and receiver for HBC in a body area network (BAN), we performed electromagnetic field analysis and simulation using the finite difference time domain (FDTD) method with various models of the human body. Further we redesigned a number of impedance-matched electrodes to allow transmission without stubs or transformers. The specific absorption rate (SAR) and transmission characteristics S21 of these electrode structures were compared for several models.

Histology of two rice bodies isolated from the stifle of an adult draught horse stallion

PubMed Central

Heimann, Marianne; Lejeune, Jean-Philippe; Verwilghen, Denis R.V.G.; Deby-Dupont, Ginette P.; Serteyn, Didier A.

2006-01-01

In the human and equine species, different kinds of free floating intra-articular particles are related to certain disorders. Osteochondral fragments formed during osteochondrosis dissecans are the most common finding in the equine species, whereas in humans rice bodies due to rheumatoid arthritis are more frequent. Herein we report a third type of floating body inside the stifle of an adult draught horse stallion, in macroscopic appearance similar to articular rice bodies known in humans. As revealed by histologic examination, the two particles consist of polypoid degenerated structures derived from synovial villi. Their formation was probably induced by ischemia. PMID:16434856

Histology of two rice bodies isolated from the stifle of an adult draught horse stallion.

PubMed

Schneider, Nicole; Heimann, Marianne; Lejeune, Jean-Philippe; Verwilghen, Denis R V G; Deby-Dupont, Ginette P; Serteyn, Didier A

2006-03-01

In the human and equine species, different kinds of free floating intra-articular particles are related to certain disorders. Osteochondral fragments formed during osteochondrosis dissecans are the most common finding in the equine species, whereas in humans rice bodies due to rheumatoid arthritis are more frequent. Herein we report a third type of floating body inside the stifle of an adult draught horse stallion, in macroscopic appearance similar to articular rice bodies known in humans. As revealed by histologic examination, the two particles consist of polypoid degenerated structures derived from synovial villi. Their formation was probably induced by ischemia.

Paths of Movement for Selected Body Segments During Typical Pilot Tasks

DTIC Science & Technology

1976-03-01

11 Scope ........... ...................... 12 Past Human Motion Investigations ........... ... 13 Experimental Techniques in Human...of.literature has been generated during the past few decades in the field of human-motion recording and analysis. However, in most of these studies body...to meet the COMBIMAN model requirements. Past Human Motion Investigations The 15th century artist-scientist, Leonardo da Vinci, is generally credited

Interpreting Musculoskeletal Models and Dynamic Simulations: Causes and Effects of Differences Between Models.

PubMed

Roelker, Sarah A; Caruthers, Elena J; Baker, Rachel K; Pelz, Nicholas C; Chaudhari, Ajit M W; Siston, Robert A

2017-11-01

With more than 29,000 OpenSim users, several musculoskeletal models with varying levels of complexity are available to study human gait. However, how different model parameters affect estimated joint and muscle function between models is not fully understood. The purpose of this study is to determine the effects of four OpenSim models (Gait2392, Lower Limb Model 2010, Full-Body OpenSim Model, and Full Body Model 2016) on gait mechanics and estimates of muscle forces and activations. Using OpenSim 3.1 and the same experimental data for all models, six young adults were scaled in each model, gait kinematics were reproduced, and static optimization estimated muscle function. Simulated measures differed between models by up to 6.5° knee range of motion, 0.012 Nm/Nm peak knee flexion moment, 0.49 peak rectus femoris activation, and 462 N peak rectus femoris force. Differences in coordinate system definitions between models altered joint kinematics, influencing joint moments. Muscle parameter and joint moment discrepancies altered muscle activations and forces. Additional model complexity yielded greater error between experimental and simulated measures; therefore, this study suggests Gait2392 is a sufficient model for studying walking in healthy young adults. Future research is needed to determine which model(s) is best for tasks with more complex motion.

A Three Dimensional Kinematic and Kinetic Study of the Golf Swing

PubMed Central

Nesbit, Steven M.

2005-01-01

This paper discusses the three-dimensional kinematics and kinetics of a golf swing as performed by 84 male and one female amateur subjects of various skill levels. The analysis was performed using a variable full-body computer model of a human coupled with a flexible model of a golf club. Data to drive the model was obtained from subject swings recorded using a multi-camera motion analysis system. Model output included club trajectories, golfer/club interaction forces and torques, work and power, and club deflections. These data formed the basis for a statistical analysis of all subjects, and a detailed analysis and comparison of the swing characteristics of four of the subjects. The analysis generated much new data concerning the mechanics of the golf swing. It revealed that a golf swing is a highly coordinated and individual motion and subject-to-subject variations were significant. The study highlighted the importance of the wrists in generating club head velocity and orienting the club face. The trajectory of the hands and the ability to do work were the factors most closely related to skill level. Key Points Full-body model of the golf swing. Mechanical description of the golf swing. Statistical analysis of golf swing mechanics. Comparisons of subject swing mechanics PMID:24627665

A three dimensional kinematic and kinetic study of the golf swing.

PubMed

Nesbit, Steven M

2005-12-01

This paper discusses the three-dimensional kinematics and kinetics of a golf swing as performed by 84 male and one female amateur subjects of various skill levels. The analysis was performed using a variable full-body computer model of a human coupled with a flexible model of a golf club. Data to drive the model was obtained from subject swings recorded using a multi-camera motion analysis system. Model output included club trajectories, golfer/club interaction forces and torques, work and power, and club deflections. These data formed the basis for a statistical analysis of all subjects, and a detailed analysis and comparison of the swing characteristics of four of the subjects. The analysis generated much new data concerning the mechanics of the golf swing. It revealed that a golf swing is a highly coordinated and individual motion and subject-to-subject variations were significant. The study highlighted the importance of the wrists in generating club head velocity and orienting the club face. The trajectory of the hands and the ability to do work were the factors most closely related to skill level. Key PointsFull-body model of the golf swing.Mechanical description of the golf swing.Statistical analysis of golf swing mechanics.Comparisons of subject swing mechanics.

The Effects of Racket Inertia Tensor on Elbow Loadings and Racket Behavior for Central and Eccentric Impacts

PubMed Central

Nesbit, Steven M.; Elzinga, Michael; Herchenroder, Catherine; Serrano, Monika

2006-01-01

This paper discusses the inertia tensors of tennis rackets and their influence on the elbow swing torques in a forehand motion, the loadings transmitted to the elbow from central and eccentric impacts, and the racket acceleration responses from central and eccentric impacts. Inertia tensors of various rackets with similar mass and mass center location were determined by an inertia pendulum and were found to vary considerably in all three orthogonal directions. Tennis swing mechanics and impact analyses were performed using a computer model comprised of a full-body model of a human, a parametric model of the racket, and an impact function. The swing mechanics analysis of a forehand motion determined that inertia values had a moderate linear effect on the pronation-supination elbow torques required to twist the racket, and a minor effect on the flexion-extension and valgus-varus torques. The impact analysis found that mass center inertia values had a considerable effect on the transmitted torques for both longitudinal and latitudinal eccentric impacts and significantly affected all elbow torque components. Racket acceleration responses to central and eccentric impacts were measured experimentally and found to be notably sensitive to impact location and mass center inertia values. Key Points Tennis biomechanics. Racket inertia tensor. Impact analysis. Full-body computer model. PMID:24260004

Low-cost compact thermal imaging sensors for body temperature measurement

NASA Astrophysics Data System (ADS)

Han, Myung-Soo; Han, Seok Man; Kim, Hyo Jin; Shin, Jae Chul; Ahn, Mi Sook; Kim, Hyung Won; Han, Yong Hee

2013-06-01

This paper presents a 32x32 microbolometer thermal imaging sensor for human body temperature measurement. Waferlevel vacuum packaging technology allows us to get a low cost and compact imaging sensor chip. The microbolometer uses V-W-O film as sensing material and ROIC has been designed 0.35-um CMOS process in UMC. A thermal image of a human face and a hand using f/1 lens convinces that it has a potential of human body temperature for commercial use.

CrossTalk: The Journal of Defense Software Engineering. Volume 20, Number 8, August 2007

DTIC Science & Technology

2007-08-01

He challenged anyone to prove or disprove that the solar system was stable. Henri Poincaré, sometimes called the Father of Chaos, was awarded the...the human body and our planet. In other words, examples of open systems are the human body and or solar system where the human body is composed of...interact- ing biological cells and our solar system with planets, stars, etc. They are like an organization where each is engaged in active transactions

The body as constitutive element phenomenology and psychoanalysis on our view of ourselves and others.

PubMed

Monjaraz Fuentes, Paulina; Rojas Hernández, María Del Carmen; Santasilia, Stefano; Monjaraz Fuentes, Fernanda

2017-12-01

The aim of this manuscript is to highlight that from the phenomenology and psychoanalysis point of view, the meaning of the notion of the body is different from the medical biologicist discourse. In psychoanalysis, the body is an erogenized body. It is constituted as an object for another self. Similarly, in phenomenology, the body is an own body in first instance. It is the body of a self, rather than a living body and a material body. Both positions enable us to understand how this conceptualization of the body is essential in any human field. Especially in the clinic, the position of the subject before the other will lead to a specific form of intervention. From this understanding of the human body, both phenomenology and psychoanalysis confirm that the biologicist understanding of the body, presumed by all psychological and medical practices, is insufficient.

Body-composition changes in the Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy (CALERIE)-2 study: A 2-y randomized controlled trial of calorie restriction in nonobese humans

USDA-ARS?s Scientific Manuscript database

Calorie restriction (CR) retards aging and increases longevity in many animal models. However, it is unclear whether CR can be implemented in humans without adverse effects on body composition. We evaluated the effect of a 2-year CR regimen on body composition including the influence of sex and body...

Current Applications of Chromatographic Methods in the Study of Human Body Fluids for Diagnosing Disorders.

PubMed

Jóźwik, Jagoda; Kałużna-Czaplińska, Joanna

2016-01-01

Currently, analysis of various human body fluids is one of the most essential and promising approaches to enable the discovery of biomarkers or pathophysiological mechanisms for disorders and diseases. Analysis of these fluids is challenging due to their complex composition and unique characteristics. Development of new analytical methods in this field has made it possible to analyze body fluids with higher selectivity, sensitivity, and precision. The composition and concentration of analytes in body fluids are most often determined by chromatography-based techniques. There is no doubt that proper use of knowledge that comes from a better understanding of the role of body fluids requires the cooperation of scientists of diverse specializations, including analytical chemists, biologists, and physicians. This article summarizes current knowledge about the application of different chromatographic methods in analyses of a wide range of compounds in human body fluids in order to diagnose certain diseases and disorders.

Neural representations of faces and body parts in macaque and human cortex: a comparative FMRI study.

PubMed

Pinsk, Mark A; Arcaro, Michael; Weiner, Kevin S; Kalkus, Jan F; Inati, Souheil J; Gross, Charles G; Kastner, Sabine

2009-05-01

Single-cell studies in the macaque have reported selective neural responses evoked by visual presentations of faces and bodies. Consistent with these findings, functional magnetic resonance imaging studies in humans and monkeys indicate that regions in temporal cortex respond preferentially to faces and bodies. However, it is not clear how these areas correspond across the two species. Here, we directly compared category-selective areas in macaques and humans using virtually identical techniques. In the macaque, several face- and body part-selective areas were found located along the superior temporal sulcus (STS) and middle temporal gyrus (MTG). In the human, similar to previous studies, face-selective areas were found in ventral occipital and temporal cortex and an additional face-selective area was found in the anterior temporal cortex. Face-selective areas were also found in lateral temporal cortex, including the previously reported posterior STS area. Body part-selective areas were identified in the human fusiform gyrus and lateral occipitotemporal cortex. In a first experiment, both monkey and human subjects were presented with pictures of faces, body parts, foods, scenes, and man-made objects, to examine the response profiles of each category-selective area to the five stimulus types. In a second experiment, face processing was examined by presenting upright and inverted faces. By comparing the responses and spatial relationships of the areas, we propose potential correspondences across species. Adjacent and overlapping areas in the macaque anterior STS/MTG responded strongly to both faces and body parts, similar to areas in the human fusiform gyrus and posterior STS. Furthermore, face-selective areas on the ventral bank of the STS/MTG discriminated both upright and inverted faces from objects, similar to areas in the human ventral temporal cortex. Overall, our findings demonstrate commonalities and differences in the wide-scale brain organization between the two species and provide an initial step toward establishing functionally homologous category-selective areas.

Neural Representations of Faces and Body Parts in Macaque and Human Cortex: A Comparative fMRI Study

PubMed Central

Pinsk, Mark A.; Arcaro, Michael; Weiner, Kevin S.; Kalkus, Jan F.; Inati, Souheil J.; Gross, Charles G.; Kastner, Sabine

2009-01-01

Single-cell studies in the macaque have reported selective neural responses evoked by visual presentations of faces and bodies. Consistent with these findings, functional magnetic resonance imaging studies in humans and monkeys indicate that regions in temporal cortex respond preferentially to faces and bodies. However, it is not clear how these areas correspond across the two species. Here, we directly compared category-selective areas in macaques and humans using virtually identical techniques. In the macaque, several face- and body part–selective areas were found located along the superior temporal sulcus (STS) and middle temporal gyrus (MTG). In the human, similar to previous studies, face-selective areas were found in ventral occipital and temporal cortex and an additional face-selective area was found in the anterior temporal cortex. Face-selective areas were also found in lateral temporal cortex, including the previously reported posterior STS area. Body part–selective areas were identified in the human fusiform gyrus and lateral occipitotemporal cortex. In a first experiment, both monkey and human subjects were presented with pictures of faces, body parts, foods, scenes, and man-made objects, to examine the response profiles of each category-selective area to the five stimulus types. In a second experiment, face processing was examined by presenting upright and inverted faces. By comparing the responses and spatial relationships of the areas, we propose potential correspondences across species. Adjacent and overlapping areas in the macaque anterior STS/MTG responded strongly to both faces and body parts, similar to areas in the human fusiform gyrus and posterior STS. Furthermore, face-selective areas on the ventral bank of the STS/MTG discriminated both upright and inverted faces from objects, similar to areas in the human ventral temporal cortex. Overall, our findings demonstrate commonalities and differences in the wide-scale brain organization between the two species and provide an initial step toward establishing functionally homologous category-selective areas. PMID:19225169

Joint Drumming: Social Context Facilitates Synchronization in Preschool Children

ERIC Educational Resources Information Center

Kirschner, Sebastian; Tomasello, Michael

2009-01-01

The human capacity to synchronize body movements to an external acoustic beat enables uniquely human behaviors such as music making and dancing. By hypothesis, these first evolved in human cultures as fundamentally social activities. We therefore hypothesized that children would spontaneously synchronize their body movements to an external beat at…

75 FR 60459 - National Committee on Vital and Health Statistics; Nominations

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-30

... (NCVHS). The NCVHS is the statutory public advisory body to the U.S. Department of Health and Human... Health Statistics serves as the statutory public advisory body to the Department of Health and Human... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Committee on Vital and Health Statistics...

21 CFR 80.35 - Color additive mixtures; certification and exemption from certification.

Code of Federal Regulations, 2011 CFR

2011-04-01

... certified if intended for use in foods, drugs, or cosmetics, or in coloring the human body, as the case may... cosmetics which color the human body, 29 FR 18495, Dec. 29, 1964. ... HEALTH AND HUMAN SERVICES GENERAL COLOR ADDITIVE CERTIFICATION Certification Procedures § 80.35 Color...

21 CFR 80.35 - Color additive mixtures; certification and exemption from certification.

Code of Federal Regulations, 2010 CFR

2010-04-01

... certified if intended for use in foods, drugs, or cosmetics, or in coloring the human body, as the case may... cosmetics which color the human body, 29 FR 18495, Dec. 29, 1964. ... HEALTH AND HUMAN SERVICES GENERAL COLOR ADDITIVE CERTIFICATION Certification Procedures § 80.35 Color...

Human and animal studies: portals into the whole body and whole population response

EPA Science Inventory

Human and animal studies: portals into the whole body and whole population response Michael C. Madden1 and Brett Winters21US Environmental Protection Agency and 2University of North Carolina Human Studies Facility, Chapel Hill, North Carolina, USA Studies involving collection and...

A finite-element simulation of galvanic coupling intra-body communication based on the whole human body.

PubMed

Song, Yong; Zhang, Kai; Hao, Qun; Hu, Lanxin; Wang, Jingwen; Shang, Fuzhou

2012-10-09

Simulation based on the finite-element (FE) method plays an important role in the investigation of intra-body communication (IBC). In this paper, a finite-element model of the whole body model used for the IBC simulation is proposed and verified, while the FE simulation of the galvanic coupling IBC with different signal transmission paths has been achieved. Firstly, a novel finite-element method for modeling the whole human body is proposed, and a FE model of the whole human body used for IBC simulation was developed. Secondly, the simulations of the galvanic coupling IBC with the different signal transmission paths were implemented. Finally, the feasibility of the proposed method was verified by using in vivo measurements within the frequency range of 10 kHz-5 MHz, whereby some important conclusions were deduced. Our results indicate that the proposed method will offer significant advantages in the investigation of the galvanic coupling intra-body communication.

A Finite-Element Simulation of Galvanic Coupling Intra-Body Communication Based on the Whole Human Body

PubMed Central

Song, Yong; Zhang, Kai; Hao, Qun; Hu, Lanxin; Wang, Jingwen; Shang, Fuzhou

2012-01-01

Simulation based on the finite-element (FE) method plays an important role in the investigation of intra-body communication (IBC). In this paper, a finite-element model of the whole body model used for the IBC simulation is proposed and verified, while the FE simulation of the galvanic coupling IBC with different signal transmission paths has been achieved. Firstly, a novel finite-element method for modeling the whole human body is proposed, and a FE model of the whole human body used for IBC simulation was developed. Secondly, the simulations of the galvanic coupling IBC with the different signal transmission paths were implemented. Finally, the feasibility of the proposed method was verified by using in vivo measurements within the frequency range of 10 kHz–5 MHz, whereby some important conclusions were deduced. Our results indicate that the proposed method will offer significant advantages in the investigation of the galvanic coupling intra-body communication. PMID:23202010

Detection of contraband concealed on the body using x-ray imaging

NASA Astrophysics Data System (ADS)

Smith, Gerald J.

1997-01-01

In an effort to avoid detection, smugglers and terrorists are increasingly using the body as a vehicle for transporting illicit drugs, weapons, and explosives. This trend illustrates the natural tendency of traffickers to seek the path of least resistance, as improved interdiction technology and operational effectiveness have been brought to bear on other trafficking avenues such as luggage, cargo, and parcels. In response, improved technology for human inspection is being developed using a variety of techniques. ASE's BodySearch X-ray Inspection Systems uses backscatter x-ray imaging of the human body to quickly, safely, and effectively screen for drugs, weapons, and explosives concealed on the body. This paper reviews the law enforcement and social issues involved in human inspections, and briefly describes the ASE BodySearch systems. Operator training, x-ray image interpretation, and maximizing systems effectiveness are also discussed. Finally, data collected from operation of the BodySearch system in the field is presented, and new law enforcement initiatives which have come about due to recent events are reviewed.

How Are Bodies Special? Effects Of Body Features On Spatial Reasoning

PubMed Central

Yu, Alfred B.; Zacks, Jeffrey M.

2015-01-01

Embodied views of cognition argue that cognitive processes are influenced by bodily experience. This implies that when people make spatial judgments about human bodies, they bring to bear embodied knowledge that affects spatial reasoning performance. Here, we examined the specific contribution to spatial reasoning of visual features associated with the human body. We used two different tasks to elicit distinct visuospatial transformations: object-based transformations, as elicited in typical mental rotation tasks, and perspective transformations, used in tasks in which people deliberately adopt the egocentric perspective of another person. Body features facilitated performance in both tasks. This result suggests that observers are particularly sensitive to the presence of a human head and body, and that these features allow observers to quickly recognize and encode the spatial configuration of a figure. Contrary to prior reports, this facilitation was not related to the transformation component of task performance. These results suggest that body features facilitate task components other than spatial transformation, including the encoding of stimulus orientation. PMID:26252072

Learn About Stem Cells

MedlinePlus

... Handbook Stem Cell Glossary Search Toggle Nav Stem Cell Basics Stem cells are the foundation from which ... Home > Learn About Stem Cells > Stem Cell Basics Cells in the human body The human body comprises ...

[Effects of testosterone and cortisol in sports fatigued organism by Chinese material medica of shixiang yaofa].

PubMed

Lu, He-qi; Wei, Bing; Chao, Zhi-mao; Deng, Yun-long; Cheng, Yu-biao; Wang, Ke-lin; Zhou, Yan-hua; Yang, Kun-jie; Zhang, Hai-zhong; Cheng, Zhao-huan

2007-08-01

To study the endogenous hormone of testosterone and cortisol that secretes volume and rhythm in sports fatigued human bodies and animals. To determine secretory volume and rhythm in sports fatigued human bodies and animals when Shixiang yaofa's drug are used. Radio-immunity method was used to determine secretory volume and rhythm in sports fatigued human bodies and animals and to analyze secretory volume and rhythm. According to the secretory volume and rhythm of testosterone and cortisol, the Shixiang Yaofa's drugs were used. Doses: wenyang jihuo bead 10 g/sack 2 sack, ziyin xiuyang capsule 0.5 g/pill 8 pill pd in human bodies for 28 days. Wenyang jihuo bead 10 g x kg(-1) of crude drug, ziyin xiuyang capsule 4 g x kg(-1) of crude drug pd for hight doses in animals. Other groups for low doses 5 g x kg(-1) and 2 g x kg(-1) of crude drug pd for 15 days. The blood samples were collected for determination. (1) In human bodies the peak value of testosterone was appeared in 8:00 and valley value was appeared in 18:00, ranges: 176.93-281.73 x 10(-5) mg x L(-1). The peak value of cortisol was appeared in 8:00 and valley value was appeared in 22:00, ranges: 1.31-16.13 x 10(-3) mg x L(-1). In the same condition, the mouse peak value of testosterone was appeared in 20:00 and valley value was appeared in 0:00, ranges: (0.56 x 10(-5) - 124.0 x 10(-5)) mg x L(-1). The rhythm in animals was compatible with human bodies, howerer, the peak value was delayed for 12 hours. (2) The testosterone was step up and the cortisol was cut down in sports fatigued human bodies and animals when shixiang yaofa's drug were used (P < 0.05, P < 0.01). The secretion of testosterone and cortisol in sports fatigued human bodies and animals are existed conclusive biologic rhythm. The secretory volume can be available accommodation by shixiang yaofa's drugs.

Body mass estimates of hominin fossils and the evolution of human body size.

PubMed

Grabowski, Mark; Hatala, Kevin G; Jungers, William L; Richmond, Brian G

2015-08-01

Body size directly influences an animal's place in the natural world, including its energy requirements, home range size, relative brain size, locomotion, diet, life history, and behavior. Thus, an understanding of the biology of extinct organisms, including species in our own lineage, requires accurate estimates of body size. Since the last major review of hominin body size based on postcranial morphology over 20 years ago, new fossils have been discovered, species attributions have been clarified, and methods improved. Here, we present the most comprehensive and thoroughly vetted set of individual fossil hominin body mass predictions to date, and estimation equations based on a large (n = 220) sample of modern humans of known body masses. We also present species averages based exclusively on fossils with reliable taxonomic attributions, estimates of species averages by sex, and a metric for levels of sexual dimorphism. Finally, we identify individual traits that appear to be the most reliable for mass estimation for each fossil species, for use when only one measurement is available for a fossil. Our results show that many early hominins were generally smaller-bodied than previously thought, an outcome likely due to larger estimates in previous studies resulting from the use of large-bodied modern human reference samples. Current evidence indicates that modern human-like large size first appeared by at least 3-3.5 Ma in some Australopithecus afarensis individuals. Our results challenge an evolutionary model arguing that body size increased from Australopithecus to early Homo. Instead, we show that there is no reliable evidence that the body size of non-erectus early Homo differed from that of australopiths, and confirm that Homo erectus evolved larger average body size than earlier hominins. Copyright © 2015 Elsevier Ltd. All rights reserved.

On the presence and role of human gene-body DNA methylation

PubMed Central

Jjingo, Daudi; Conley, Andrew B.; Yi, Soojin V.; Lunyak, Victoria V.; Jordan, I. King

2012-01-01

DNA methylation of promoter sequences is a repressive epigenetic mark that down-regulates gene expression. However, DNA methylation is more prevalent within gene-bodies than seen for promoters, and gene-body methylation has been observed to be positively correlated with gene expression levels. This paradox remains unexplained, and accordingly the role of DNA methylation in gene-bodies is poorly understood. We addressed the presence and role of human gene-body DNA methylation using a meta-analysis of human genome-wide methylation, expression and chromatin data sets. Methylation is associated with transcribed regions as genic sequences have higher levels of methylation than intergenic or promoter sequences. We also find that the relationship between gene-body DNA methylation and expression levels is non-monotonic and bell-shaped. Mid-level expressed genes have the highest levels of gene-body methylation, whereas the most lowly and highly expressed sets of genes both have low levels of methylation. While gene-body methylation can be seen to efficiently repress the initiation of intragenic transcription, the vast majority of methylated sites within genes are not associated with intragenic promoters. In fact, highly expressed genes initiate the most intragenic transcription, which is inconsistent with the previously held notion that gene-body methylation serves to repress spurious intragenic transcription to allow for efficient transcriptional elongation. These observations lead us to propose a model to explain the presence of human gene-body methylation. This model holds that the repression of intragenic transcription by gene-body methylation is largely epiphenomenal, and suggests that gene-body methylation levels are predominantly shaped via the accessibility of the DNA to methylating enzyme complexes. PMID:22577155

Materiality, Technology, and Constructing Social Knowledge through Bodily Representation: A View from Prehistoric Guernsey, Channel Islands

PubMed Central

Kohring, Sheila

2015-01-01

The role of the human body in the creation of social knowledge—as an ontological and/or aesthetic category—has been applied across social theory. In all these approaches, the body is viewed as a locus for experience and knowledge. If the body is a source of subjective knowledge, then it can also become an important means of creating ontological categories of self and society. The materiality of human representations within art traditions, then, can be interpreted as providing a means for contextualizing and aestheticizing the body in order to produce a symbolic and structural knowledge category. This paper explores the effect of material choices and techniques of production when representing the human body on how societies order and categorize the world. PMID:26290654

Materiality, Technology, and Constructing Social Knowledge through Bodily Representation: A View from Prehistoric Guernsey, Channel Islands.

PubMed

Kohring, Sheila

2015-04-22

The role of the human body in the creation of social knowledge-as an ontological and/or aesthetic category-has been applied across social theory. In all these approaches, the body is viewed as a locus for experience and knowledge. If the body is a source of subjective knowledge, then it can also become an important means of creating ontological categories of self and society. The materiality of human representations within art traditions, then, can be interpreted as providing a means for contextualizing and aestheticizing the body in order to produce a symbolic and structural knowledge category. This paper explores the effect of material choices and techniques of production when representing the human body on how societies order and categorize the world.

A systematic review of the human body burden of e-waste exposure in China.

PubMed

Song, Qingbin; Li, Jinhui

2014-07-01

As China is one of the countries facing the most serious pollution and human exposure effects of e-waste in the world, much of the population there is exposed to potentially hazardous substances due to informal e-waste recycling processes. This report reviews recent studies on human exposure to e-waste in China, with particular focus on exposure routes (e.g. dietary intake, inhalation, and soil/dust ingestion) and human body burden markers (e.g. placenta, umbilical cord blood, breast milk, blood, hair, and urine) and assesses the evidence for the association between such e-waste exposure and the human body burden in China. The results suggest that residents in the e-waste exposure areas, located mainly in the three traditional e-waste recycling sites (Taizhou, Guiyu, and Qingyuan), are faced with a potential higher daily intake of these pollutants than residents in the control areas, especially via food ingestion. Moreover, pollutants (PBBs, PBDEs, PCBs, PCDD/Fs, and heavy metals) from the e-waste recycling processes were all detectable in the tissue samples at high levels, showing that they had entered residents' bodies through the environment and dietary exposure. Children and neonates are the groups most sensitive to the human body effects of e-waste exposure. We also recorded plausible outcomes associated with exposure to e-waste, including 7 types of human body burden. Although the data suggest that exposure to e-waste is harmful to health, better designed epidemiological investigations in vulnerable populations, especially neonates and children, are needed to confirm these associations. Copyright © 2014 Elsevier Ltd. All rights reserved.

Metabolic costs and evolutionary implications of human brain development.

PubMed

Kuzawa, Christopher W; Chugani, Harry T; Grossman, Lawrence I; Lipovich, Leonard; Muzik, Otto; Hof, Patrick R; Wildman, Derek E; Sherwood, Chet C; Leonard, William R; Lange, Nicholas

2014-09-09

The high energetic costs of human brain development have been hypothesized to explain distinctive human traits, including exceptionally slow and protracted preadult growth. Although widely assumed to constrain life-history evolution, the metabolic requirements of the growing human brain are unknown. We combined previously collected PET and MRI data to calculate the human brain's glucose use from birth to adulthood, which we compare with body growth rate. We evaluate the strength of brain-body metabolic trade-offs using the ratios of brain glucose uptake to the body's resting metabolic rate (RMR) and daily energy requirements (DER) expressed in glucose-gram equivalents (glucosermr% and glucoseder%). We find that glucosermr% and glucoseder% do not peak at birth (52.5% and 59.8% of RMR, or 35.4% and 38.7% of DER, for males and females, respectively), when relative brain size is largest, but rather in childhood (66.3% and 65.0% of RMR and 43.3% and 43.8% of DER). Body-weight growth (dw/dt) and both glucosermr% and glucoseder% are strongly, inversely related: soon after birth, increases in brain glucose demand are accompanied by proportionate decreases in dw/dt. Ages of peak brain glucose demand and lowest dw/dt co-occur and subsequent developmental declines in brain metabolism are matched by proportionate increases in dw/dt until puberty. The finding that human brain glucose demands peak during childhood, and evidence that brain metabolism and body growth rate covary inversely across development, support the hypothesis that the high costs of human brain development require compensatory slowing of body growth rate.

Comparative investigation of body composition in male dogs using CT and body fat analysis software.

PubMed

Kobayashi, Toyokazu; Koie, Hiroshi; Kusumi, Akiko; Kitagawa, Masato; Kanayama, Kiichi; Otsuji, Kazuya

2014-03-01

In small animal veterinary practices, body condition score (BCS) is generally used to diagnose obesity. However, BCS does not constitute objective data. In this study, we investigated the value of using human body fat analysis software for male dogs. We also compared changes in body fat after neutering. Changes in body fat at the time of neutering (age 1 year) and 1 year later were compared by performing CT scanning and using human body fat analysis software. We found that body fat increased in all the individuals tested. In terms of the site of fat accumulation, subcutaneous fat was more pronounced than visceral fat with a marked increase on the dorsal side of the abdomen rather than the thorax.

Recovery of bioactive protein from bacterial inclusion bodies using trifluoroethanol as solubilization agent.

PubMed

Upadhyay, Vaibhav; Singh, Anupam; Jha, Divya; Singh, Akansha; Panda, Amulya K

2016-06-08

Formation of inclusion bodies poses a major hurdle in recovery of bioactive recombinant protein from Escherichia coli. Urea and guanidine hydrochloride have routinely been used to solubilize inclusion body proteins, but many times result in poor recovery of bioactive protein. High pH buffers, detergents and organic solvents like n-propanol have been successfully used as mild solubilization agents for high throughput recovery of bioactive protein from bacterial inclusion bodies. These mild solubilization agents preserve native-like secondary structures of proteins in inclusion body aggregates and result in improved recovery of bioactive protein as compared to conventional solubilization agents. Here we demonstrate solubilization of human growth hormone inclusion body aggregates using 30% trifluoroethanol in presence of 3 M urea and its refolding into bioactive form. Human growth hormone was expressed in E. coli M15 (pREP) cells in the form of inclusion bodies. Different concentrations of trifluoroethanol with or without addition of low concentration (3 M) of urea were used for solubilization of inclusion body aggregates. Thirty percent trifluoroethanol in combination with 3 M urea was found to be suitable for efficient solubilization of human growth hormone inclusion bodies. Solubilized protein was refolded by dilution and purified by anion exchange and size exclusion chromatography. Purified protein was analyzed for secondary and tertiary structure using different spectroscopic tools and was found to be bioactive by cell proliferation assay. To understand the mechanism of action of trifluoroethanol, secondary and tertiary structure of human growth hormone in trifluoroethanol was compared to that in presence of other denaturants like urea and guanidine hydrochloride. Trifluoroethanol was found to be stabilizing the secondary structure and destabilizing the tertiary structure of protein. Finally, it was observed that trifluoroethanol can be used to solubilize inclusion bodies of a number of proteins. Trifluoroethanol was found to be a suitable mild solubilization agent for bacterial inclusion bodies. Fully functional, bioactive human growth hormone was recovered in high yield from inclusion bodies using trifluoroethanol based solubilization buffer. It was also observed that trifluoroethanol has potential to solubilize inclusion bodies of different proteins.

Functional specialization and convergence in the occipito-temporal cortex supporting haptic and visual identification of human faces and body parts: an fMRI study.

PubMed

Kitada, Ryo; Johnsrude, Ingrid S; Kochiyama, Takanori; Lederman, Susan J

2009-10-01

Humans can recognize common objects by touch extremely well whenever vision is unavailable. Despite its importance to a thorough understanding of human object recognition, the neuroscientific study of this topic has been relatively neglected. To date, the few published studies have addressed the haptic recognition of nonbiological objects. We now focus on haptic recognition of the human body, a particularly salient object category for touch. Neuroimaging studies demonstrate that regions of the occipito-temporal cortex are specialized for visual perception of faces (fusiform face area, FFA) and other body parts (extrastriate body area, EBA). Are the same category-sensitive regions activated when these components of the body are recognized haptically? Here, we use fMRI to compare brain organization for haptic and visual recognition of human body parts. Sixteen subjects identified exemplars of faces, hands, feet, and nonbiological control objects using vision and haptics separately. We identified two discrete regions within the fusiform gyrus (FFA and the haptic face region) that were each sensitive to both haptically and visually presented faces; however, these two regions differed significantly in their response patterns. Similarly, two regions within the lateral occipito-temporal area (EBA and the haptic body region) were each sensitive to body parts in both modalities, although the response patterns differed. Thus, although the fusiform gyrus and the lateral occipito-temporal cortex appear to exhibit modality-independent, category-sensitive activity, our results also indicate a degree of functional specialization related to sensory modality within these structures.

Towards an understanding of the link between environmental emissions and human body burdens of PCBs using CoZMoMAN.

PubMed

Breivik, Knut; Czub, Gertje; McLachlan, Michael S; Wania, Frank

2010-01-01

Different factors affect how organic contaminants released into the environment over time distribute and accumulate, enter various food-chains, and potentially cause toxic effects in wildlife and humans. A sound chemical risk assessment thus requires the determination of the quantitative relationship between emissions and human exposure. This study aimed to assess the extent of the quantitative and mechanistic understanding of the link between environmental emissions and human body burdens for polychlorinated biphenyls (PCBs) in the western part of the Baltic Sea drainage basin and to identify any remaining knowledge gaps. An integrated, non-steady state model calculating human body burden from environmental emissions (CoZMoMAN) was created by linking the multi-compartment environmental fate model CoZMo-POP 2 with the human food chain bioaccumulation model ACC-HUMAN. CoZMoMAN predicted concentrations of seven PCB congeners in 11 key model compartments to typically within a factor of 2 to 4 of measured values, although larger discrepancies are noted for soils and humans. We conclude that whereas the most important processes which link emissions of PCBs to human body burdens are quite well understood in this region, some critical knowledge gaps related to the time trend of historical emissions remain to be addressed.

Additive effects of affective arousal and top-down attention on the event-related brain responses to human bodies.

PubMed

Hietanen, Jari K; Kirjavainen, Ilkka; Nummenmaa, Lauri

2014-12-01

The early visual event-related 'N170 response' is sensitive to human body configuration and it is enhanced to nude versus clothed bodies. We tested whether the N170 response as well as later EPN and P3/LPP responses to nude bodies reflect the effect of increased arousal elicited by these stimuli, or top-down allocation of object-based attention to the nude bodies. Participants saw pictures of clothed and nude bodies and faces. In each block, participants were asked to direct their attention towards stimuli from a specified target category while ignoring others. Object-based attention did not modulate the N170 amplitudes towards attended stimuli; instead N170 response was larger to nude bodies compared to stimuli from other categories. Top-down attention and affective arousal had additive effects on the EPN and P3/LPP responses reflecting later processing stages. We conclude that nude human bodies have a privileged status in the visual processing system due to the affective arousal they trigger. Copyright © 2014 Elsevier B.V. All rights reserved.

Finite element modeling for predicting the contact pressure between a foam mattress and the human body in a supine position.

PubMed

Lee, Wookjin; Won, Byeong Hee; Cho, Seong Wook

2017-01-01

In this paper, we generated finite element (FE) models to predict the contact pressure between a foam mattress and the human body in a supine position. Twenty-year-old males were used for three-dimensional scanning to produce the FE human models, which was composed of skin and muscle tissue. A linear elastic isotropic material model was used for the skin, and the Mooney-Rivlin model was used for the muscle tissue because it can effectively represent the nonlinear behavior of muscle. The contact pressure between the human model and the mattress was predicted by numerical simulation. The human models were validated by comparing the body pressure distribution obtained from the same human subject when he was lying on two different mattress types. The experimental results showed that the slope of the lower part of the mattress caused a decrease in the contact pressure at the heels, and the effect of bone structure was most pronounced in the scapula. After inserting a simple structure to function as the scapula, the contact pressure predicted by the FE human models was consistent with the experimental body pressure distribution for all body parts. These results suggest that the models proposed in this paper will be useful to researchers and designers of products related to the prevention of pressure ulcers.

41 CFR 102-41.20 - What definitions apply to this part?

Code of Federal Regulations, 2010 CFR

2010-07-01

..., compounding, converting, concealing, processing, preparing, or introducing into the human body a controlled... oil, PCP, or amphetamines into the human body. Eleemosynary institution means any nonprofit health or...

41 CFR 102-41.20 - What definitions apply to this part?

Code of Federal Regulations, 2011 CFR

2011-01-01

..., compounding, converting, concealing, processing, preparing, or introducing into the human body a controlled... oil, PCP, or amphetamines into the human body. Eleemosynary institution means any nonprofit health or...

Body Art: Connecting Past and Future

ERIC Educational Resources Information Center

Rosko, Keith A.

2005-01-01

Young people are using the human body as a canvas. What they fail to realize is that they are participating in a form of artistic expression that is nearly as old as human existence. Keith Rosco observed his students' fascinations with tattoo and henna, he decided body art might make an excellent topic for study, guaranteed to keep students'…

New Materialist Ontologies in Mathematics Education: The Body in/of Mathematics

ERIC Educational Resources Information Center

de Freitas, Elizabeth; Sinclair, Nathalie

2013-01-01

In this paper we study the mathematical body as an assemblage of human and non-human mathematical concepts. We argue that learners' bodies are always in the process of becoming assemblages of diverse and dynamic materialities. Following the work of the historian of science Karen Barad, we argue that mathematical concepts must be considered dynamic…

Cognitive Analysis of Chinese-English Metaphors of Animal and Human Body Part Words

ERIC Educational Resources Information Center

Song, Meiying

2009-01-01

Metaphorical cognition arises from the mapping of two conceptual domains onto each other. According to the "Anthropocentrism", people tend to know the world first by learning about their bodies including Apparatuses. Based on that, people begin to know the material world, and the human body part metaphorization emerges as the times…

21 CFR 701.20 - Detergent substances, other than soap, intended for use in cleansing the body.

Code of Federal Regulations, 2010 CFR

2010-04-01

... represented only as soap. (b) Products intended for cleansing the human body and which are not “soap” as set... for use in cleansing the body. 701.20 Section 701.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS COSMETIC LABELING Labeling of Specific...

21 CFR 701.20 - Detergent substances, other than soap, intended for use in cleansing the body.

Code of Federal Regulations, 2011 CFR

2011-04-01

... represented only as soap. (b) Products intended for cleansing the human body and which are not “soap” as set... use in cleansing the body. 701.20 Section 701.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS COSMETIC LABELING Labeling of Specific...

Dust to dust - How a human corpse decomposes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vass, Arpad Alexander

2010-01-01

After death, the human body decomposes through four stages. The final, skeleton stage may be reached as quickly as two weeks or as slowly as two years, depending on temperature, humidity and other environmental conditions where the body lies. Dead bodies emit a surprising array of chemicals, from benzene to freon, which can help forensic scientists find clandestine graves.

[The human body, subject or object of rights?

PubMed

Rachet-Darfeuille, Véronique

While the protection of the body is the primary vocation of law, legislation also aims to regulate any actions which may cause it harm. Such actions include care procedures. It is in this contradiction that the legal status of the human body lies, not without a certain amount of ambiguity. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

Surface analytical studies of maxillofacial implants: influence of the preoperational treatment and the human body on the surface properties of retrieved implants.

PubMed

Kiss, Gábor; Sebők, Béla; Szabó, Péter J; Joób, Arpád F; Szabó, György

2014-05-01

In the present work, surface analytical investigation of unimplanted as well as retrieved pyrolytic carbon-covered carbon/carbon composite implants and Ti osteosynthesis plates is reported. The Ti plates were covered by a 200-nm-thick, anodically and thermally formed TiO2 layer. Our results suggest that although the oxide layer on the Ti miniplates remained stable during the time spent in the human body, there is still material transport between the implant and the human body. In case of the carbon/carbon composite implants, damage of the carbon fibers constituting the material was found on one side of the sterile implant and attributed to the manufacturing process. The NaCl crystals originally present on the surface of the sterile material disappeared during the time spent in the human body. As a result of the interaction with the human body, a new surface layer (mainly constituted of carbon) appeared on the implant. The results indicate that both the time spent in the human organism and the preparation of the implants before operation can have detectable effects on the investigated surface properties. Surface analytical investigations could therefore provide information not only about the biocompatibility of these materials but also about the effect of their treatment before operation.

Role of VGF-derived carboxy-terminal peptides in energy balance and reproduction: analysis of "humanized" knockin mice expressing full-length or truncated VGF.

PubMed

Sadahiro, Masato; Erickson, Connor; Lin, Wei-Jye; Shin, Andrew C; Razzoli, Maria; Jiang, Cheng; Fargali, Samira; Gurney, Allison; Kelley, Kevin A; Buettner, Christoph; Bartolomucci, Alessandro; Salton, Stephen R

2015-05-01

Targeted deletion of VGF, a secreted neuronal and endocrine peptide precursor, produces lean, hypermetabolic, and infertile mice that are resistant to diet-, lesion-, and genetically-induced obesity and diabetes. Previous studies suggest that VGF controls energy expenditure (EE), fat storage, and lipolysis, whereas VGF C-terminal peptides also regulate reproductive behavior and glucose homeostasis. To assess the functional equivalence of human VGF(1-615) (hVGF) and mouse VGF(1-617) (mVGF), and to elucidate the function of the VGF C-terminal region in the regulation of energy balance and susceptibility to obesity, we generated humanized VGF knockin mouse models expressing full-length hVGF or a C-terminally deleted human VGF(1-524) (hSNP), encoded by a single nucleotide polymorphism (rs35400704). We show that homozygous male and female hVGF and hSNP mice are fertile. hVGF female mice had significantly increased body weight compared with wild-type mice, whereas hSNP mice have reduced adiposity, increased activity- and nonactivity-related EE, and improved glucose tolerance, indicating that VGF C-terminal peptides are not required for reproductive function, but 1 or more specific VGF C-terminal peptides are likely to be critical regulators of EE. Taken together, our results suggest that human and mouse VGF proteins are largely functionally conserved but that species-specific differences in VGF peptide function, perhaps a result of known differences in receptor binding affinity, likely alter the metabolic phenotype of hVGF compared with mVGF mice, and in hSNP mice in which several C-terminal VGF peptides are ablated, result in significantly increased activity- and nonactivity-related EE.

Type II PI4-kinases control Weibel-Palade body biogenesis and von Willebrand factor structure in human endothelial cells.

PubMed

Lopes da Silva, Mafalda; O'Connor, Marie N; Kriston-Vizi, Janos; White, Ian J; Al-Shawi, Raya; Simons, J Paul; Mössinger, Julia; Haucke, Volker; Cutler, Daniel F

2016-05-15

Weibel-Palade bodies (WPBs) are endothelial storage organelles that mediate the release of molecules involved in thrombosis, inflammation and angiogenesis, including the pro-thrombotic glycoprotein von Willebrand factor (VWF). Although many protein components required for WPB formation and function have been identified, the role of lipids is almost unknown. We examined two key phosphatidylinositol kinases that control phosphatidylinositol 4-phosphate levels at the trans-Golgi network, the site of WPB biogenesis. RNA interference of the type II phosphatidylinositol 4-kinases PI4KIIα and PI4KIIβ in primary human endothelial cells leads to formation of an increased proportion of short WPB with perturbed packing of VWF, as exemplified by increased exposure of antibody-binding sites. When stimulated with histamine, these cells release normal levels of VWF yet, under flow, form very few platelet-catching VWF strings. In PI4KIIα-deficient mice, immuno-microscopy revealed that VWF packaging is also perturbed and these mice exhibit increased blood loss after tail cut compared to controls. This is the first demonstration that lipid kinases can control the biosynthesis of VWF and the formation of WPBs that are capable of full haemostatic function. © 2016. Published by The Company of Biologists Ltd.

[Perfluoroalkyl substances: emerging environmental contaminants involving potential health risk].

PubMed

Li, Jingguang

2015-06-01

Perfluoroalkyl substances (PFASs) have been distributed in environment and human body worldwide. Due to their bioaccumulative and multiple organ toxic, these compounds have raised more and more attention in recent years. The precursors of PFASs can be metabolized to PFASs both in environment and human body, which makes an important contribution to human body burdens. Apart from transformation into PFASs, some of these precursors themselves or their metabolic intermediates also have toxicity effects, such as estrogen-like properties, protein binding, cytotoxicity and so on, and there might be a potential harmful impact on human health. In this paper, the toxicity and biotransformation of PFASs and their precursors were introduced briefly.

Performance of human body communication-based wearable ECG with capacitive coupling electrodes

PubMed Central

Sakuma, Jun; Anzai, Daisuke

2016-01-01

Wearable electrocardiogram (ECG) is attracting much attention in daily healthcare applications, and human body communication (HBC) technology provides an evident advantage in making the sensing electrodes of ECG also working for transmission through the human body. In view of actual usage in daily life, however, non-contact electrodes to the human body are desirable. In this Letter, the authors discussed the ECG circuit structure in the HBC-based wearable ECG for removing the common mode noise when employing non-contact capacitive coupling electrodes. Through the comparison of experimental results, they have shown that the authors’ proposed circuit structure with the third electrode directly connected to signal ground can provide an effect on common mode noise reduction similar to the usual drive-right-leg circuit, and a sufficiently good acquisition performance of ECG signals. PMID:27733931

Analysis of measured data of human body based on error correcting frequency

NASA Astrophysics Data System (ADS)

Jin, Aiyan; Peipei, Gao; Shang, Xiaomei

2014-04-01

Anthropometry is to measure all parts of human body surface, and the measured data is the basis of analysis and study of the human body, establishment and modification of garment size and formulation and implementation of online clothing store. In this paper, several groups of the measured data are gained, and analysis of data error is gotten by analyzing the error frequency and using analysis of variance method in mathematical statistics method. Determination of the measured data accuracy and the difficulty of measured parts of human body, further studies of the causes of data errors, and summarization of the key points to minimize errors possibly are also mentioned in the paper. This paper analyses the measured data based on error frequency, and in a way , it provides certain reference elements to promote the garment industry development.

Performance of human body communication-based wearable ECG with capacitive coupling electrodes.

PubMed

Sakuma, Jun; Anzai, Daisuke; Wang, Jianqing

2016-09-01

Wearable electrocardiogram (ECG) is attracting much attention in daily healthcare applications, and human body communication (HBC) technology provides an evident advantage in making the sensing electrodes of ECG also working for transmission through the human body. In view of actual usage in daily life, however, non-contact electrodes to the human body are desirable. In this Letter, the authors discussed the ECG circuit structure in the HBC-based wearable ECG for removing the common mode noise when employing non-contact capacitive coupling electrodes. Through the comparison of experimental results, they have shown that the authors' proposed circuit structure with the third electrode directly connected to signal ground can provide an effect on common mode noise reduction similar to the usual drive-right-leg circuit, and a sufficiently good acquisition performance of ECG signals.

Impact of indoor environment on path loss in body area networks.

PubMed

Hausman, Sławomir; Januszkiewicz, Łukasz

2014-10-20

In this paper the influence of an example indoor environment on narrowband radio channel path loss for body area networks operating around 2.4 GHz is investigated using computer simulations and on-site measurements. In contrast to other similar studies, the simulation model included both a numerical human body phantom and its environment-room walls, floor and ceiling. As an example, radio signal attenuation between two different configurations of transceivers with dipole antennas placed in a direct vicinity of a human body (on-body scenario) is analyzed by computer simulations for several types of reflecting environments. In the analyzed case the propagation environments comprised a human body and office room walls. As a reference environment for comparison, free space with only a conducting ground plane, modelling a steel mesh reinforced concrete floor, was chosen. The transmitting and receiving antennas were placed in two on-body configurations chest-back and chest-arm. Path loss vs. frequency simulation results obtained using Finite Difference Time Domain (FDTD) method and a multi-tissue anthropomorphic phantom were compared to results of measurements taken with a vector network analyzer with a human subject located in an average-size empty cuboidal office room. A comparison of path loss values in different environments variants gives some qualitative and quantitative insight into the adequacy of simplified indoor environment model for the indoor body area network channel representation.

Impact of Indoor Environment on Path Loss in Body Area Networks

PubMed Central

Hausman, Sławomir; Januszkiewicz, Łukasz

2014-01-01

In this paper the influence of an example indoor environment on narrowband radio channel path loss for body area networks operating around 2.4 GHz is investigated using computer simulations and on-site measurements. In contrast to other similar studies, the simulation model included both a numerical human body phantom and its environment—room walls, floor and ceiling. As an example, radio signal attenuation between two different configurations of transceivers with dipole antennas placed in a direct vicinity of a human body (on-body scenario) is analyzed by computer simulations for several types of reflecting environments. In the analyzed case the propagation environments comprised a human body and office room walls. As a reference environment for comparison, free space with only a conducting ground plane, modelling a steel mesh reinforced concrete floor, was chosen. The transmitting and receiving antennas were placed in two on-body configurations chest–back and chest–arm. Path loss vs. frequency simulation results obtained using Finite Difference Time Domain (FDTD) method and a multi-tissue anthropomorphic phantom were compared to results of measurements taken with a vector network analyzer with a human subject located in an average-size empty cuboidal office room. A comparison of path loss values in different environments variants gives some qualitative and quantitative insight into the adequacy of simplified indoor environment model for the indoor body area network channel representation. PMID:25333289

Evaluation and Verification of Channel Transmission Characteristics of Human Body for Optimizing Data Transmission Rate in Electrostatic-Coupling Intra Body Communication System: A Comparative Analysis

PubMed Central

Tseng, Yuhwai; Su, Chauchin; Ho, Yingchieh

2016-01-01

Background Intra-body communication is a new wireless scheme for transmitting signals through the human body. Understanding the transmission characteristics of the human body is therefore becoming increasingly important. Electrostatic-coupling intra-body communication system in a ground-free situation that integrate electronic products that are discretely located on individuals, such as mobile phones, PDAs, wearable computers, and biomedical sensors, are of particular interest. Materials and Methods The human body is modeled as a simplified Resistor-Capacitor network. A virtual ground between the transmitter and receiver in the system is represented by a resister-capacitor network. Value of its resistance and capacitance are determined from a system perspective. The system is characterized by using a mathematical unit step function in digital baseband transmission scheme with and without Manchester code. As a result, the signal-to-noise and to-intersymbol-interference ratios are improved by manipulating the load resistor. The data transmission rate of the system is optimized. A battery-powered transmitter and receiver are developed to validate the proposal. Results A ground-free system fade signal energy especially for a low-frequency signal limited system transmission rate. The system transmission rate is maximized by simply manipulating the load resistor. Experimental results demonstrate that for a load resistance of 10k−50k Ω, the high-pass 3 dB frequency of the band-pass channel is 400kHz−2MHz in the worst-case scenario. The system allows a Manchester-coded baseband signal to be transmitted at speeds of up to 20M bit per second with signal-to-noise and signal-to-intersymbol-interference ratio of more than 10 dB. Conclusion The human body can function as a high speed transmission medium with a data transmission rate of 20Mbps in an electrostatic-coupling intra-body communication system. Therefore, a wideband signal can be transmitted directly through the human body with a good signal-to-noise quality of 10 dB if the high-pass 3 dB frequency is suitably selected. PMID:26866602

Evaluation and Verification of Channel Transmission Characteristics of Human Body for Optimizing Data Transmission Rate in Electrostatic-Coupling Intra Body Communication System: A Comparative Analysis.

PubMed

Tseng, Yuhwai; Su, Chauchin; Ho, Yingchieh

2016-01-01

Intra-body communication is a new wireless scheme for transmitting signals through the human body. Understanding the transmission characteristics of the human body is therefore becoming increasingly important. Electrostatic-coupling intra-body communication system in a ground-free situation that integrate electronic products that are discretely located on individuals, such as mobile phones, PDAs, wearable computers, and biomedical sensors, are of particular interest. The human body is modeled as a simplified Resistor-Capacitor network. A virtual ground between the transmitter and receiver in the system is represented by a resister-capacitor network. Value of its resistance and capacitance are determined from a system perspective. The system is characterized by using a mathematical unit step function in digital baseband transmission scheme with and without Manchester code. As a result, the signal-to-noise and to-intersymbol-interference ratios are improved by manipulating the load resistor. The data transmission rate of the system is optimized. A battery-powered transmitter and receiver are developed to validate the proposal. A ground-free system fade signal energy especially for a low-frequency signal limited system transmission rate. The system transmission rate is maximized by simply manipulating the load resistor. Experimental results demonstrate that for a load resistance of 10k-50k Ω, the high-pass 3 dB frequency of the band-pass channel is 400kHz-2MHz in the worst-case scenario. The system allows a Manchester-coded baseband signal to be transmitted at speeds of up to 20M bit per second with signal-to-noise and signal-to-intersymbol-interference ratio of more than 10 dB. The human body can function as a high speed transmission medium with a data transmission rate of 20Mbps in an electrostatic-coupling intra-body communication system. Therefore, a wideband signal can be transmitted directly through the human body with a good signal-to-noise quality of 10 dB if the high-pass 3 dB frequency is suitably selected.

Brief communication: Hair density and body mass in mammals and the evolution of human hairlessness.

PubMed

Sandel, Aaron A

2013-09-01

Humans are unusual among mammals in appearing hairless. Several hypotheses propose explanations for this phenotype, but few data are available to test these hypotheses. To elucidate the evolutionary history of human "hairlessness," a comparative approach is needed. One previous study on primate hair density concluded that great apes have systematically less dense hair than smaller primates. While there is a negative correlation between body size and hair density, it remains unclear whether great apes have less dense hair than is expected for their body size. To revisit the scaling relationship between hair density and body size in mammals, I compiled data from the literature on 23 primates and 29 nonprimate mammals and conducted Phylogenetic Generalized Least Squares regressions. Among anthropoids, there is a significant negative correlation between hair density and body mass. Chimpanzees display the largest residuals, exhibiting less dense hair than is expected for their body size. There is a negative correlation between hair density and body mass among the broader mammalian sample, although the functional significance of this scaling relationship remains to be tested. Results indicate that all primates, and chimpanzees in particular, are relatively hairless compared to other mammals. This suggests that there may have been selective pressures acting on the ancestor of humans and chimpanzees that led to an initial reduction in hair density. To further understand the evolution of human hairlessness, a systematic study of hair density and physiology in a wide range of species is necessary. Copyright © 2013 Wiley Periodicals, Inc.

How to pass information and deliver energy to a network of implantable devices within the human body.

PubMed

Sun, Mingui; Hackworth, Steven A; Tang, Zhide; Gilbert, Gary; Cardin, Sylvain; Sclabassi, Robert J

2007-01-01

It has been envisioned that a body network can be built to collect data from, and transport information to, implanted miniature devices at multiple sites within the human body. Currently, two problems of utmost importance remain unsolved: 1) how to link information between a pair of implants at a distance? and 2) how to provide electric power to these implants allowing them to function and communicate? In this paper, we present new solutions to these problems by minimizing the intra-body communication distances. We show that, based on a study of human anatomy, the maximum distance from the body surface to the deepest point inside the body is approximately 15 cm. This finding provides an upper bound for the lengths of communication pathways required to reach the body's interior. We also show that these pathways do not have to cross any joins within the body. In order to implement the envisioned body network, we present the design of a new device, called an energy pad. This small-size, light-weight device can easily interface with the skin to perform data communication with, and supply power to, miniature implants.

A cross-species translational pharmacokinetic-pharmacodynamic evaluation of core body temperature reduction by the TRPM8 blocker PF-05105679.

PubMed

Gosset, James R; Beaumont, Kevin; Matsuura, Tomomi; Winchester, Wendy; Attkins, Neil; Glatt, Sophie; Lightbown, Ian; Ulrich, Kristina; Roberts, Sonia; Harris, Jolie; Mesic, Emir; van Steeg, Tamara; Hijdra, Diana; van der Graaf, Piet H

2017-11-15

PF-05105679 is a moderately potent TRPM8 blocker which has been evaluated for the treatment of cold pain sensitivity. The TRPM8 channel is responsible for the sensation of cold environmental temperatures and has been implicated in regulation of core body temperature. Consequently, blockade of TRPM8 has been suggested to result in lowering of core body temperature. As part of the progression to human studies, the effect of PF-05105679 on core body temperature has been investigated in animals. Safety pharmacology studies showed that PF-05105679 reduced core body temperature in a manner that was inversely related to body weight of the species tested (greater exposure to PF-05105679 was required to lower temperature by 1°C in higher species). Based on an allometric (body weight) relationship, it was hypothesized that PF-05105679 would not lower core body temperature in humans at exposures that could exhibit pharmacological effects on cold pain sensation. On administration to humans, PF-05105679 was indeed effective at reversing the cold pain sensation associated with the cold pressor test in the absence of effects on core body temperature. Copyright © 2017 Elsevier B.V. All rights reserved.

The Artificial World of Plastination: A Challenge to Religious Perspectives on the Dead Human Body.

PubMed

Jones, David Gareth

2016-11-01

The public exhibitions of plastinated (preserved) and dissected human cadavers have proved exceedingly popular and also very contentious. However, there has been little in the way of sustained analysis of these exhibitions from a Christian angle. The technique of plastination enables whole bodies to be displayed as though standing and playing a variety of sports, and with 'life-like' facial expressions. In analyzing this phenomenon, the plastination procedure is outlined, and the degree of naturalness of the whole body plastinates assessed. In searching for theological directives the debate over burial and cremation is used as a means of exploring the respect we give the dead body, and the significance of the resurrection of the body for our views of the dead body. In particular, attention is paid to devaluation of the dead body in situations ranging from dissection of the body through to commercial public exhibitions. The centrality of notions of altruism and 'gift' is discussed. It is concluded that there are many disquieting features to these exhibitions, necessitating caution in approaching them. Nevertheless, in reminding visitors of their mortality and the wonders of the human body, they are not to be dismissed entirely.

Advancing the sexual and reproductive health and human rights of women living with HIV: a review of UN, regional and national human rights norms and standards

PubMed Central

Khosla, Rajat; Van Belle, Nuna; Temmerman, Marleen

2015-01-01

Introduction The right to sexual and reproductive health (SRH) is an essential part of the right to health and is dependent upon substantive equality, including freedom from multiple and intersecting forms of discrimination that result in exclusion in both law and practice. Nonetheless, general and specific SRH needs of women living with HIV are often not adequately addressed. For example, services that women living with HIV need may not be available or may have multiple barriers, in particular stigma and discrimination. This study was conducted to review United Nations Human Rights Council, Treaty Monitoring Bodies and Special Rapporteur reports and regional and national mechanisms regarding SRH issues of women living with HIV. The objective is to assess areas of progress, as well as gaps, in relation to health and human rights considerations in the work of these normative bodies on health and human rights. Methods The review was done using keywords of international, regional and national jurisprudence on findings covering the 2000 to 2014 period for documents in English; searches for the Inter-American Commission on Human Rights and national judgments were also conducted in Spanish. Jurisprudence of UN Treaty Monitoring Bodies, regional mechanisms and national bodies was considered in this regard. Results and discussion In total, 236 findings were identified using the search strategy, and of these 129 were selected for review based on the inclusion criteria. The results highlight that while jurisprudence from international, regional and national bodies reflects consideration of some health and human rights issues related to women living with HIV and SRH, the approach of these bodies has been largely ad hoc and lacks a systematic integration of human rights concerns of women living with HIV in relation to SRH. Most findings relate to non-discrimination, accessibility, informed decision-making and accountability. There are critical gaps on normative standards regarding the human rights of women living with HIV in relation to SRH. Conclusions A systematic approach to health and human rights considerations related to women living with HIV and SRH by international, regional and national bodies is needed to advance the agenda and ensure that policies and programmes related to SRH systematically take into account the health and human rights of women living with HIV. PMID:26643455

Advancing the sexual and reproductive health and human rights of women living with HIV: a review of UN, regional and national human rights norms and standards.

PubMed

Khosla, Rajat; Van Belle, Nuna; Temmerman, Marleen

2015-01-01

The right to sexual and reproductive health (SRH) is an essential part of the right to health and is dependent upon substantive equality, including freedom from multiple and intersecting forms of discrimination that result in exclusion in both law and practice. Nonetheless, general and specific SRH needs of women living with HIV are often not adequately addressed. For example, services that women living with HIV need may not be available or may have multiple barriers, in particular stigma and discrimination. This study was conducted to review United Nations Human Rights Council, Treaty Monitoring Bodies and Special Rapporteur reports and regional and national mechanisms regarding SRH issues of women living with HIV. The objective is to assess areas of progress, as well as gaps, in relation to health and human rights considerations in the work of these normative bodies on health and human rights. The review was done using keywords of international, regional and national jurisprudence on findings covering the 2000 to 2014 period for documents in English; searches for the Inter-American Commission on Human Rights and national judgments were also conducted in Spanish. Jurisprudence of UN Treaty Monitoring Bodies, regional mechanisms and national bodies was considered in this regard. In total, 236 findings were identified using the search strategy, and of these 129 were selected for review based on the inclusion criteria. The results highlight that while jurisprudence from international, regional and national bodies reflects consideration of some health and human rights issues related to women living with HIV and SRH, the approach of these bodies has been largely ad hoc and lacks a systematic integration of human rights concerns of women living with HIV in relation to SRH. Most findings relate to non-discrimination, accessibility, informed decision-making and accountability. There are critical gaps on normative standards regarding the human rights of women living with HIV in relation to SRH. A systematic approach to health and human rights considerations related to women living with HIV and SRH by international, regional and national bodies is needed to advance the agenda and ensure that policies and programmes related to SRH systematically take into account the health and human rights of women living with HIV.

Developmental variation in ecogeographic body proportions.

PubMed

Cowgill, Libby W; Eleazer, Courtney D; Auerbach, Benjamin M; Temple, Daniel H; Okazaki, Kenji

2012-08-01

While ecogeographic variation in adult human body proportions has been extensively explored, relatively less attention has been paid to the effect of Bergmann's and Allen's rules on human body shape during growth. The relationship between climate and immature body form is particularly important, as immature mortality is high, mechanisms of thermoregulation differ between young and mature humans, and immature body proportions fluctuate due to basic parameters of growth. This study explores changes in immature ecogeographic body proportions via analyses of anthropometric data from children included in Eveleth and Tanner's (1976) Worldwide Variation in Human Growth, as well as limb proportion measurements in eight different skeletal samples. Moderate to strong correlations exist between climatic data and immature stature, weight, BMI, and bi-iliac breadth; these relationships are as strong, if not stronger, in immature individuals as they are in adults. Correlations between climate and trunk height relative to stature are weak or nonexistent. Altitude also has significant effects on immature body form, with children from higher altitudes displaying smaller statures and lower body weights. Brachial and crural indices remain constant over the course of growth and display consistent, moderate correlations with latitude across ontogeny that are just as high as those detected in adults. The results of this study suggest that while some features of immature body form, such as bi-iliac breadth and intralimb indices, are strongly dictated by ecogeographic principles, other characteristics of immature body proportions are influenced by intrinsic and extrinsic factors such as nutrition and basic constraints of growth. Copyright © 2012 Wiley Periodicals, Inc.

What's in a name: the taxonomic status of human head and body lice.

PubMed

Light, Jessica E; Toups, Melissa A; Reed, David L

2008-06-01

Human head lice (Anoplura: Pediculidae: Pediculus) are pandemic, parasitizing countless school children worldwide due to the evolution of insecticide resistance, and human body (clothing) lice are responsible for the deaths of millions as a result of vectoring several deadly bacterial pathogens. Despite the obvious impact these lice have had on their human hosts, it is unclear whether head and body lice represent two morphological forms of a single species or two distinct species. To assess the taxonomic status of head and body lice, we provide a synthesis of publicly available molecular data in GenBank, and we compare phylogenetic and population genetic methods using the most diverse geographic and molecular sampling presently available. Our analyses find reticulated networks, gene flow, and a lack of reciprocal monophyly, all of which indicate that head and body lice do not represent genetically distinct evolutionary units. Based on these findings, as well as inconsistencies of morphological, behavioral, and ecological variability between head and body lice, we contend that no known species concept would recognize these louse morphotypes as separate species. We recommend recognizing head and body lice as morphotypes of a single species, Pediculus humanus, until compelling new data and analyses (preferably analyses of fast evolving nuclear markers in a coalescent framework) indicate otherwise.