SU-F-T-140: Assessment of the Proton Boron Fusion Reaction for Practical Radiation Therapy Applications Using MCNP6

DOE Office of Scientific and Technical Information (OSTI.GOV)

Adam, D; Bednarz, B

Purpose: The proton boron fusion reaction is a reaction that describes the creation of three alpha particles as the result of the interaction of a proton incident upon a 11B target. Theoretically, the proton boron fusion reaction is a desirable reaction for radiation therapy applications in that, with the appropriate boron delivery agent, it could potentially combine the localized dose delivery protons exhibit (Bragg peak) and the local deposition of high LET alpha particles in cancerous sites. Previous efforts have shown significant dose enhancement using the proton boron fusion reaction; the overarching purpose of this work is an attempt tomore » validate previous Monte Carlo results of the proton boron fusion reaction. Methods: The proton boron fusion reaction, 11B(p, 3α), is investigated using MCNP6 to assess the viability for potential use in radiation therapy. Simple simulations of a proton pencil beam incident upon both a water phantom and a water phantom with an axial region containing 100ppm boron were modeled using MCNP6 in order to determine the extent of the impact boron had upon the calculated energy deposition. Results: The maximum dose increase calculated was 0.026% for the incident 250 MeV proton beam scenario. The MCNP simulations performed demonstrated that the proton boron fusion reaction rate at clinically relevant boron concentrations was too small in order to have any measurable impact on the absorbed dose. Conclusion: For all MCNP6 simulations conducted, the increase of absorbed dose of a simple water phantom due to the 11B(p, 3α) reaction was found to be inconsequential. In addition, it was determined that there are no good evaluations of the 11B(p, 3α) reaction for use in MCNPX/6 and further work should be conducted in cross section evaluations in order to definitively evaluate the feasibility of the proton boron fusion reaction for use in radiation therapy applications.« less

Cooperative angle-only orbit initialization via fusion of admissible areas

NASA Astrophysics Data System (ADS)

Jia, Bin; Pham, Khanh; Blasch, Erik; Chen, Genshe; Shen, Dan; Wang, Zhonghai

2017-05-01

For the short-arc angle only orbit initialization problem, the admissible area is often used. However, the accuracy using a single sensor is often limited. For high value space objects, it is desired to achieve more accurate results. Fortunately, multiple sensors, which are dedicated to space situational awareness, are available. The work in this paper uses multiple sensors' information to cooperatively initialize the orbit based on the fusion of multiple admissible areas. Both the centralized fusion and decentralized fusion are discussed. Simulation results verify the expectation that the orbit initialization accuracy is improved by using information from multiple sensors.

Multi-Sensor Systems and Data Fusion for Telecommunications, Remote Sensing and Radar (les Systemes multi-senseurs et le fusionnement des donnees pour les telecommunications, la teledetection et les radars)

DTIC Science & Technology

1998-04-01

The result of the project is a demonstration of the fusion process, the sensors management and the real-time capabilities using simulated sensors...demonstrator (TAD) is a system that demonstrates the core ele- ment of a battlefield ground surveillance system by simulation in near real-time. The core...Management and Sensor/Platform simulation . The surveillance system observes the real world through a non-collocated heterogene- ous multisensory system

Membrane Fusion Involved in Neurotransmission: Glimpse from Electron Microscope and Molecular Simulation

PubMed Central

Yang, Zhiwei; Gou, Lu; Chen, Shuyu; Li, Na; Zhang, Shengli; Zhang, Lei

2017-01-01

Membrane fusion is one of the most fundamental physiological processes in eukaryotes for triggering the fusion of lipid and content, as well as the neurotransmission. However, the architecture features of neurotransmitter release machinery and interdependent mechanism of synaptic membrane fusion have not been extensively studied. This review article expounds the neuronal membrane fusion processes, discusses the fundamental steps in all fusion reactions (membrane aggregation, membrane association, lipid rearrangement and lipid and content mixing) and the probable mechanism coupling to the delivery of neurotransmitters. Subsequently, this work summarizes the research on the fusion process in synaptic transmission, using electron microscopy (EM) and molecular simulation approaches. Finally, we propose the future outlook for more exciting applications of membrane fusion involved in synaptic transmission, with the aid of stochastic optical reconstruction microscopy (STORM), cryo-EM (cryo-EM), and molecular simulations. PMID:28638320

Molecular Dynamics Simulations of Folding and Insertion of the Ebola Virus Fusion Peptide into a Membrane Bilayer

DTIC Science & Technology

2008-07-01

Molecular Dynamics Simulations of Folding and Insertion of the Ebola Virus Fusion Peptide into a Membrane Bilayer Mark A. Olson1, In...presents replica-exchange molecular dynamics simulations of the folding and insertion of a 16- residue Ebola virus fusion peptide into a membrane...separate calculated structures into conformational basins. 2.1 Simulation models Molecular dynamics simulations were performed using the all-atom

Simulation and assessment of ion kinetic effects in a direct-drive capsule implosion experiment

DOE PAGES

Le, Ari Yitzchak; Kwan, Thomas J. T.; Schmitt, Mark J.; ...

2016-10-24

The first simulations employing a kinetic treatment of both fuel and shell ions to model inertial confinement fusion experiments are presented, including results showing the importance of kinetic physics processes in altering fusion burn. A pair of direct drive capsule implosions performed at the OMEGA facility with two different gas fills of deuterium, tritium, and helium-3 are analyzed. During implosion shock convergence, highly non-Maxwellian ion velocity distributions and separations in the density and temperature amongst the ion species are observed. Finally, diffusion of fuel into the capsule shell is identified as a principal process that degrades fusion burn performance.

Simulation of Carbon Production from Material Surfaces in Fusion Devices

NASA Astrophysics Data System (ADS)

Marian, J.; Verboncoeur, J.

2005-10-01

Impurity production at carbon surfaces by plasma bombardment is a key issue for fusion devices as modest amounts can lead to excessive radiative power loss and/or hydrogenic D-T fuel dilution. Here results of molecular dynamics (MD) simulations of physical and chemical sputtering of hydrocarbons are presented for models of graphite and amorphous carbon, the latter formed by continuous D-T impingement in conditions that mimic fusion devices. The results represent more extensive simulations than we reported last year, including incident energies in the 30-300 eV range for a variety of incident angles that yield a number of different hydrocarbon molecules. The calculated low-energy yields clarify the uncertainty in the complex chemical sputtering rate since chemical bonding and hard-core repulsion are both included in the interatomic potential. Also modeled is hydrocarbon break-up by electron-impact collisions and transport near the surface. Finally, edge transport simulations illustrate the sensitivity of the edge plasma properties arising from moderate changes in the carbon content. The models will provide the impurity background for the TEMPEST kinetic edge code.

Distributed data fusion across multiple hard and soft mobile sensor platforms

NASA Astrophysics Data System (ADS)

Sinsley, Gregory

One of the biggest challenges currently facing the robotics field is sensor data fusion. Unmanned robots carry many sophisticated sensors including visual and infrared cameras, radar, laser range finders, chemical sensors, accelerometers, gyros, and global positioning systems. By effectively fusing the data from these sensors, a robot would be able to form a coherent view of its world that could then be used to facilitate both autonomous and intelligent operation. Another distinct fusion problem is that of fusing data from teammates with data from onboard sensors. If an entire team of vehicles has the same worldview they will be able to cooperate much more effectively. Sharing worldviews is made even more difficult if the teammates have different sensor types. The final fusion challenge the robotics field faces is that of fusing data gathered by robots with data gathered by human teammates (soft sensors). Humans sense the world completely differently from robots, which makes this problem particularly difficult. The advantage of fusing data from humans is that it makes more information available to the entire team, thus helping each agent to make the best possible decisions. This thesis presents a system for fusing data from multiple unmanned aerial vehicles, unmanned ground vehicles, and human observers. The first issue this thesis addresses is that of centralized data fusion. This is a foundational data fusion issue, which has been very well studied. Important issues in centralized fusion include data association, classification, tracking, and robotics problems. Because these problems are so well studied, this thesis does not make any major contributions in this area, but does review it for completeness. The chapter on centralized fusion concludes with an example unmanned aerial vehicle surveillance problem that demonstrates many of the traditional fusion methods. The second problem this thesis addresses is that of distributed data fusion. Distributed data fusion is a younger field than centralized fusion. The main issues in distributed fusion that are addressed are distributed classification and distributed tracking. There are several well established methods for performing distributed fusion that are first reviewed. The chapter on distributed fusion concludes with a multiple unmanned vehicle collaborative test involving an unmanned aerial vehicle and an unmanned ground vehicle. The third issue this thesis addresses is that of soft sensor only data fusion. Soft-only fusion is a newer field than centralized or distributed hard sensor fusion. Because of the novelty of the field, the chapter on soft only fusion contains less background information and instead focuses on some new results in soft sensor data fusion. Specifically, it discusses a novel fuzzy logic based soft sensor data fusion method. This new method is tested using both simulations and field measurements. The biggest issue addressed in this thesis is that of combined hard and soft fusion. Fusion of hard and soft data is the newest area for research in the data fusion community; therefore, some of the largest theoretical contributions in this thesis are in the chapter on combined hard and soft fusion. This chapter presents a novel combined hard and soft data fusion method based on random set theory, which processes random set data using a particle filter. Furthermore, the particle filter is designed to be distributed across multiple robots and portable computers (used by human observers) so that there is no centralized failure point in the system. After laying out a theoretical groundwork for hard and soft sensor data fusion the thesis presents practical applications for hard and soft sensor data fusion in simulation. Through a series of three progressively more difficult simulations, some important hard and soft sensor data fusion capabilities are demonstrated. The first simulation demonstrates fusing data from a single soft sensor and a single hard sensor in order to track a car that could be driving normally or erratically. The second simulation adds the extra complication of classifying the type of target to the simulation. The third simulation uses multiple hard and soft sensors, with a limited field of view, to track a moving target and classify it as a friend, foe, or neutral. The final chapter builds on the work done in previous chapters by performing a field test of the algorithms for hard and soft sensor data fusion. The test utilizes an unmanned aerial vehicle, an unmanned ground vehicle, and a human observer with a laptop. The test is designed to mimic a collaborative human and robot search and rescue problem. This test makes some of the most important practical contributions of the thesis by showing that the algorithms that have been developed for hard and soft sensor data fusion are capable of running in real time on relatively simple hardware.

Fusion Simulation Project Workshop Report

NASA Astrophysics Data System (ADS)

Kritz, Arnold; Keyes, David

2009-03-01

The mission of the Fusion Simulation Project is to develop a predictive capability for the integrated modeling of magnetically confined plasmas. This FSP report adds to the previous activities that defined an approach to integrated modeling in magnetic fusion. These previous activities included a Fusion Energy Sciences Advisory Committee panel that was charged to study integrated simulation in 2002. The report of that panel [Journal of Fusion Energy 20, 135 (2001)] recommended the prompt initiation of a Fusion Simulation Project. In 2003, the Office of Fusion Energy Sciences formed a steering committee that developed a project vision, roadmap, and governance concepts [Journal of Fusion Energy 23, 1 (2004)]. The current FSP planning effort involved 46 physicists, applied mathematicians and computer scientists, from 21 institutions, formed into four panels and a coordinating committee. These panels were constituted to consider: Status of Physics Components, Required Computational and Applied Mathematics Tools, Integration and Management of Code Components, and Project Structure and Management. The ideas, reported here, are the products of these panels, working together over several months and culminating in a 3-day workshop in May 2007.

Adaptive polarization image fusion based on regional energy dynamic weighted average

NASA Astrophysics Data System (ADS)

Zhao, Yong-Qiang; Pan, Quan; Zhang, Hong-Cai

2005-11-01

According to the principle of polarization imaging and the relation between Stokes parameters and the degree of linear polarization, there are much redundant and complementary information in polarized images. Since man-made objects and natural objects can be easily distinguished in images of degree of linear polarization and images of Stokes parameters contain rich detailed information of the scene, the clutters in the images can be removed efficiently while the detailed information can be maintained by combining these images. An algorithm of adaptive polarization image fusion based on regional energy dynamic weighted average is proposed in this paper to combine these images. Through an experiment and simulations, most clutters are removed by this algorithm. The fusion method is used for different light conditions in simulation, and the influence of lighting conditions on the fusion results is analyzed.

Method of constructing a microwave antenna

NASA Technical Reports Server (NTRS)

Ngo, Phong (Inventor); Arndt, G. Dickey (Inventor); Carl, James (Inventor)

2003-01-01

A method, simulation, and apparatus are provided that are highly suitable for treatment of benign prostatic hyperplasia (BPH). A catheter is disclosed that includes a small diameter disk loaded monopole antenna surrounded by fusion material having a high heat of fusion and a melting point preferably at or near body temperature. Microwaves from the antenna heat prostatic tissue to promote necrosing of the prostatic tissue that relieves the pressure of the prostatic tissue against the urethra as the body reabsorbs the necrosed or dead tissue. The fusion material keeps the urethra cool by means of the heat of fusion of the fusion material. This prevents damage to the urethra while the prostatic tissue is necrosed. A computer simulation is provided that can be used to predict the resulting temperature profile produced in the prostatic tissue. By changing the various control features of the catheter and method of applying microwave energy a temperature profile can be predicted and produced that is similar to the temperature profile desired for the particular patient.

Method of Constructing a Microwave Antenna

NASA Technical Reports Server (NTRS)

Arndt, G. Dickey (Inventor); Carl, James (Inventor); Ngo, Phong (Inventor)

2003-01-01

A method, simulation, and apparatus are provided that are highly suitable for treatment of benign prostatic hyperplasia (BPH). A catheter is disclosed that includes a small diameter disk loaded monopole antenna surrounded by fusion material having a high heat of fusion and a melting point preferably at or near body temperature. Microwaves from the antenna heat prostatic tissue to promote necrosing of the prostatic tissue that relieves the pressure of the prostatic tissue against the urethra as the body reabsorbs the necrosed or dead tissue. The fusion material keeps the urethra cool by means of the heat of fusion of the fusion material. This prevents damage to the urethra while the prostatic tissue is necrosed. A computer simulation is provided that can be used to predict the resulting temperature profile produced in the prostatic tissue. By changing the various control features of the catheter and method of applying microwave energy a temperature profile can be predicted and produced that is similar to the temperature profile desired for the particular patient.

Method for selective thermal ablation

NASA Technical Reports Server (NTRS)

Ngo, Phong (Inventor); Arndt, G. Dickey (Inventor); Raffoul, George W. (Inventor); Carl, James (Inventor)

2003-01-01

A method, simulation, and apparatus are provided that are highly suitable for treatment of benign prostatic hyperplasia (BPH). A catheter is disclosed that includes a small diameter disk loaded monopole antenna surrounded by fusion material having a high heat of fusion and a melting point preferably at or near body temperature. Microwaves from the antenna heat prostatic tissue to promote necrosing of the prostatic tissue that relieves the pressure of the prostatic tissue against the urethra as the body reabsorbs the necrosed or dead tissue. The fusion material keeps the urethra cool by means of the heat of fusion of the fusion material. This prevents damage to the urethra while the prostatic tissue is necrosed. A computer simulation is provided that can be used to predict the resulting temperature profile produced in the prostatic tissue. By changing the various control features of the catheter and method of applying microwave energy a temperature profile can be predicted and produced that is similar to the temperature profile desired for the particular patient.

Method for Selective Thermal Ablation

NASA Technical Reports Server (NTRS)

Arndt, G. Dickey (Inventor); Carl, James (Inventor); Ngo, Phong (Inventor); Raffoul, George W. (Inventor)

2003-01-01

A method, simulation, and apparatus are provided that are highly suitable for treatment of benign prostatic hyperplasia (BPH). A catheter is disclosed that includes a small diameter disk loaded monopole antenna surrounded by fusion material having a high heat of fusion and a melting point preferably at or near body temperature. Microwaves from the antenna heat prostatic tissue to promote necrosing of the prostatic tissue that relieves the pressure of the prostatic tissue against the urethra as the body reabsorbs the necrosed or dead tissue. The fusion material keeps the urethra cool by means of the heat of fusion of the fusion material. This prevents damage to the urethra while the prostatic tissue is necrosed. A computer simulation is provided that can be used to predict the resulting temperature profile produced in the prostatic tissue. By changing the various control features of the catheter and method of applying microwave energy a temperature profile can be predicted and produced that is similar to the temperature profile desired for the particular patient.

Transcatheter Microwave Antenna

NASA Technical Reports Server (NTRS)

Arndt, Dickey G. (Inventor); Carl, James R. (Inventor); Ngo, Phong (Inventor); Raffoul, George W. (Inventor)

2001-01-01

A method, simulation, and apparatus are provided that are highly suitable for treatment of benign prostatic hyperplasia (BPH). A catheter is disclosed that includes a small diameter disk loaded monopole antenna surrounded by fusion material having a high heat of fusion and a melting point preferably at or near body temperature. Microwaves from the antenna heat prostatic tissue to promote necrosing of the prostatic tissue that relieves the pressure of the prostatic tissue against the urethra as the body reabsorbs the necrosed or dead tissue. The fusion material keeps the urethra cool by means of the heat of fusion of the fusion material. This prevents damage to the urethra while the prostatic tissue is necrosed. A computer simulation is provided that can be used to predict the resulting temperature profile produced in the prostatic tissue. By changing the various control features of the catheter and method of applying microwave energy a temperature profile can be predicted and produced that is similar to the temperature profile desired for the particular patient.

High-gain magnetized inertial fusion.

PubMed

Slutz, Stephen A; Vesey, Roger A

2012-01-13

Magnetized inertial fusion (MIF) could substantially ease the difficulty of reaching plasma conditions required for significant fusion yields, but it has been widely accepted that the gain is not sufficient for fusion energy. Numerical simulations are presented showing that high-gain MIF is possible in cylindrical liner implosions based on the MagLIF concept [S. A. Slutz et al Phys. Plasmas 17, 056303 (2010)] with the addition of a cryogenic layer of deuterium-tritium (DT). These simulations show that a burn wave propagates radially from the magnetized hot spot into the surrounding much denser cold DT given sufficient hot-spot areal density. For a drive current of 60 MA the simulated gain exceeds 100, which is more than adequate for fusion energy applications. The simulated gain exceeds 1000 for a drive current of 70 MA.

Simulation of the hybrid and steady state advanced operating modes in ITER

NASA Astrophysics Data System (ADS)

Kessel, C. E.; Giruzzi, G.; Sips, A. C. C.; Budny, R. V.; Artaud, J. F.; Basiuk, V.; Imbeaux, F.; Joffrin, E.; Schneider, M.; Murakami, M.; Luce, T.; St. John, Holger; Oikawa, T.; Hayashi, N.; Takizuka, T.; Ozeki, T.; Na, Y.-S.; Park, J. M.; Garcia, J.; Tucillo, A. A.

2007-09-01

Integrated simulations are performed to establish a physics basis, in conjunction with present tokamak experiments, for the operating modes in the International Thermonuclear Experimental Reactor (ITER). Simulations of the hybrid mode are done using both fixed and free-boundary 1.5D transport evolution codes including CRONOS, ONETWO, TSC/TRANSP, TOPICS and ASTRA. The hybrid operating mode is simulated using the GLF23 and CDBM05 energy transport models. The injected powers are limited to the negative ion neutral beam, ion cyclotron and electron cyclotron heating systems. Several plasma parameters and source parameters are specified for the hybrid cases to provide a comparison of 1.5D core transport modelling assumptions, source physics modelling assumptions, as well as numerous peripheral physics modelling. Initial results indicate that very strict guidelines will need to be imposed on the application of GLF23, for example, to make useful comparisons. Some of the variations among the simulations are due to source models which vary widely among the codes used. In addition, there are a number of peripheral physics models that should be examined, some of which include fusion power production, bootstrap current, treatment of fast particles and treatment of impurities. The hybrid simulations project to fusion gains of 5.6-8.3, βN values of 2.1-2.6 and fusion powers ranging from 350 to 500 MW, under the assumptions outlined in section 3. Simulations of the steady state operating mode are done with the same 1.5D transport evolution codes cited above, except the ASTRA code. In these cases the energy transport model is more difficult to prescribe, so that energy confinement models will range from theory based to empirically based. The injected powers include the same sources as used for the hybrid with the possible addition of lower hybrid. The simulations of the steady state mode project to fusion gains of 3.5-7, βN values of 2.3-3.0 and fusion powers of 290 to 415 MW, under the assumptions described in section 4. These simulations will be presented and compared with particular focus on the resulting temperature profiles, source profiles and peripheral physics profiles. The steady state simulations are at an early stage and are focused on developing a range of safety factor profiles with 100% non-inductive current.

Simulated disparity and peripheral blur interact during binocular fusion.

PubMed

Maiello, Guido; Chessa, Manuela; Solari, Fabio; Bex, Peter J

2014-07-17

We have developed a low-cost, practical gaze-contingent display in which natural images are presented to the observer with dioptric blur and stereoscopic disparity that are dependent on the three-dimensional structure of natural scenes. Our system simulates a distribution of retinal blur and depth similar to that experienced in real-world viewing conditions by emmetropic observers. We implemented the system using light-field photographs taken with a plenoptic camera which supports digital refocusing anywhere in the images. We coupled this capability with an eye-tracking system and stereoscopic rendering. With this display, we examine how the time course of binocular fusion depends on depth cues from blur and stereoscopic disparity in naturalistic images. Our results show that disparity and peripheral blur interact to modify eye-movement behavior and facilitate binocular fusion, and the greatest benefit was gained by observers who struggled most to achieve fusion. Even though plenoptic images do not replicate an individual’s aberrations, the results demonstrate that a naturalistic distribution of depth-dependent blur may improve 3-D virtual reality, and that interruptions of this pattern (e.g., with intraocular lenses) which flatten the distribution of retinal blur may adversely affect binocular fusion. © 2014 ARVO.

Simulated disparity and peripheral blur interact during binocular fusion

PubMed Central

Maiello, Guido; Chessa, Manuela; Solari, Fabio; Bex, Peter J

2014-01-01

We have developed a low-cost, practical gaze-contingent display in which natural images are presented to the observer with dioptric blur and stereoscopic disparity that are dependent on the three-dimensional structure of natural scenes. Our system simulates a distribution of retinal blur and depth similar to that experienced in real-world viewing conditions by emmetropic observers. We implemented the system using light-field photographs taken with a plenoptic camera which supports digital refocusing anywhere in the images. We coupled this capability with an eye-tracking system and stereoscopic rendering. With this display, we examine how the time course of binocular fusion depends on depth cues from blur and stereoscopic disparity in naturalistic images. Our results show that disparity and peripheral blur interact to modify eye-movement behavior and facilitate binocular fusion, and the greatest benefit was gained by observers who struggled most to achieve fusion. Even though plenoptic images do not replicate an individual's aberrations, the results demonstrate that a naturalistic distribution of depth-dependent blur may improve 3-D virtual reality, and that interruptions of this pattern (e.g., with intraocular lenses) which flatten the distribution of retinal blur may adversely affect binocular fusion. PMID:25034260

The Fusion of Membranes and Vesicles: Pathway and Energy Barriers from Dissipative Particle Dynamics

PubMed Central

Grafmüller, Andrea; Shillcock, Julian; Lipowsky, Reinhard

2009-01-01

The fusion of lipid bilayers is studied with dissipative particle dynamics simulations. First, to achieve control over membrane properties, the effects of individual simulation parameters are studied and optimized. Then, a large number of fusion events for a vesicle and a planar bilayer are simulated using the optimized parameter set. In the observed fusion pathway, configurations of individual lipids play an important role. Fusion starts with individual lipids assuming a splayed tail configuration with one tail inserted in each membrane. To determine the corresponding energy barrier, we measure the average work for interbilayer flips of a lipid tail, i.e., the average work to displace one lipid tail from one bilayer to the other. This energy barrier is found to depend strongly on a certain dissipative particle dynamics parameter, and, thus, can be adjusted in the simulations. Overall, three subprocesses have been identified in the fusion pathway. Their energy barriers are estimated to lie in the range 8–15 kBT. The fusion probability is found to possess a maximum at intermediate tension values. As one decreases the tension, the fusion probability seems to vanish before the tensionless membrane state is attained. This would imply that the tension has to exceed a certain threshold value to induce fusion. PMID:19348749

Numerically Simulating Collisions of Plastic and Foam Laser-Driven Foils

NASA Astrophysics Data System (ADS)

Zalesak, S. T.; Velikovich, A. L.; Schmitt, A. J.; Aglitskiy, Y.; Metzler, N.

2007-11-01

Interest in experiments on colliding planar foils has recently been stimulated by (a) the Impact Fast Ignition approach to laser fusion [1], and (b) the approach to a high-repetition rate ignition facility based on direct drive with the KrF laser [2]. Simulating the evolution of perturbations to such foils can be a numerical challenge, especially if the initial perturbation amplitudes are small. We discuss the numerical issues involved in such simulations, describe their benchmarking against recently-developed analytic results, and present simulations of such experiments on NRL's Nike laser. [1] M. Murakami et al., Nucl. Fusion 46, 99 (2006) [2] S. P. Obenschain et al., Phys. Plasmas 13, 056320 (2006).

SciDAC GSEP: Gyrokinetic Simulation of Energetic Particle Turbulence and Transport

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lin, Zhihong

Energetic particle (EP) confinement is a key physics issue for burning plasma experiment ITER, the crucial next step in the quest for clean and abundant energy, since ignition relies on self-heating by energetic fusion products (α-particles). Due to the strong coupling of EP with burning thermal plasmas, plasma confinement property in the ignition regime is one of the most uncertain factors when extrapolating from existing fusion devices to the ITER tokamak. EP population in current tokamaks are mostly produced by auxiliary heating such as neutral beam injection (NBI) and radio frequency (RF) heating. Remarkable progress in developing comprehensive EP simulationmore » codes and understanding basic EP physics has been made by two concurrent SciDAC EP projects GSEP funded by the Department of Energy (DOE) Office of Fusion Energy Science (OFES), which have successfully established gyrokinetic turbulence simulation as a necessary paradigm shift for studying the EP confinement in burning plasmas. Verification and validation have rapidly advanced through close collaborations between simulation, theory, and experiment. Furthermore, productive collaborations with computational scientists have enabled EP simulation codes to effectively utilize current petascale computers and emerging exascale computers. We review here key physics progress in the GSEP projects regarding verification and validation of gyrokinetic simulations, nonlinear EP physics, EP coupling with thermal plasmas, and reduced EP transport models. Advances in high performance computing through collaborations with computational scientists that enable these large scale electromagnetic simulations are also highlighted. These results have been widely disseminated in numerous peer-reviewed publications including many Phys. Rev. Lett. papers and many invited presentations at prominent fusion conferences such as the biennial International Atomic Energy Agency (IAEA) Fusion Energy Conference and the annual meeting of the American Physics Society, Division of Plasma Physics (APS-DPP).« less

Compression of magnetized target in the magneto-inertial fusion

NASA Astrophysics Data System (ADS)

Kuzenov, V. V.

2017-12-01

This paper presents a mathematical model, numerical method and results of the computer analysis of the compression process and the energy transfer in the target plasma, used in magneto-inertial fusion. The computer simulation of the compression process of magnetized cylindrical target by high-power laser pulse is presented.

Splaying of aliphatic tails plays a central role in barrier crossing during liposome fusion.

PubMed

Mirjanian, Dina; Dickey, Allison N; Hoh, Jan H; Woolf, Thomas B; Stevens, Mark J

2010-09-02

The fusion between two lipid bilayers involves crossing a complicated energy landscape. The limiting barrier in the process appears to be between two closely opposed bilayers and the intermediate state where the outer leaflets are fused. We have performed molecular dynamics simulations to characterize the free energy barrier for the fusion of two liposomes and to examine the molecular details of barrier crossing. To capture the slow dynamics of fusion, a model using coarse-grained representations of lipids was used. The fusion between pairs of liposomes was simulated for four systems: DPPC, DOPC, a 3:1 mixture of DPPC/DPPE, and an asymmetric lipid tail system in which one tail of DPPC was reduced to half the length (ASTail). The weighted histogram method was used to compute the free energy as a function of separation distance. The relative barrier heights for these systems was found to be ASTail > DPPC > DPPC/DPPE > DOPC, in agreement with experimental observations. Further, the free energy curves for all four can be overlaid on a single curve by plotting the free energy versus the surface separation (differing only in the point of fusion). These simulations also confirm that the two main contributions to the free energy barrier are the removal of water between the vesicles and the deformation of the vesicle. The most prominent molecular detail of barrier crossing in all cases examined was the splaying of lipid tails, where initially a single splayed lipid formed a bridge between the two outer leaflets that promotes additional lipid mixing between the vesicles and eventually leads to fusion. The tail splay appears to be closely connected to the energetics of the process. For example, the high barrier for the ASTail is the result of a smaller distance between terminal methyl groups in the splayed molecule. The shortening of this distance requires the liposomes to be closer together, which significantly increases the cost of water removal and bilayer deformation. Before tail splay can initiate fusion, contact must occur between a tail end and the external water. In isolated vesicles, the contact fraction is correlated to the fusogenicity difference between DPPC and DOPC. Moreover, for planar bilayers, the contact fraction is much lower for DPPC, which is consistent with its lack of fusion in giant vesicles. The simulation results show the key roles of lipid tail dynamics in governing the fusion energy landscape.

Novel cooperative neural fusion algorithms for image restoration and image fusion.

PubMed

Xia, Youshen; Kamel, Mohamed S

2007-02-01

To deal with the problem of restoring degraded images with non-Gaussian noise, this paper proposes a novel cooperative neural fusion regularization (CNFR) algorithm for image restoration. Compared with conventional regularization algorithms for image restoration, the proposed CNFR algorithm can relax need of the optimal regularization parameter to be estimated. Furthermore, to enhance the quality of restored images, this paper presents a cooperative neural fusion (CNF) algorithm for image fusion. Compared with existing signal-level image fusion algorithms, the proposed CNF algorithm can greatly reduce the loss of contrast information under blind Gaussian noise environments. The performance analysis shows that the proposed two neural fusion algorithms can converge globally to the robust and optimal image estimate. Simulation results confirm that in different noise environments, the proposed two neural fusion algorithms can obtain a better image estimate than several well known image restoration and image fusion methods.

Exploring the membrane fusion mechanism through force-induced disassembly of HIV-1 six-helix bundle

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gao, Kai; Beijing Key Laboratory of Noncoding RNA, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101; University of Chinese Academy of Sciences, Beijing 100049

Enveloped virus, such as HIV-1, employs membrane fusion mechanism to invade into host cell. HIV-1 gp41 ectodomain uses six-helix bundle configuration to accomplish this process. Using molecular dynamic simulations, we confirmed the stability of this six-helix bundle by showing high occupancy of hydrogen bonds and hydrophobic interactions. Key residues and interactions important for the bundle integration were characterized by force-induced unfolding simulations of six-helix bundle, exhibiting the collapse order of these groups of interactions. Moreover, our results in some way concerted with a previous theory that the formation of coiled-coil choose a route which involved cooperative interactions between the N-terminalmore » and C-terminal helix. -- Highlights: •Unfolding of HIV-1 gp41 six-helix bundle is studied by molecular dynamics simulations. •Specific interactions responsible for the stability of HIV-1 envelope post-fusion conformation were identified. •The gp41 six-helix bundle transition inducing membrane fusion might be a cooperative process of the three subunits.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kawamoto, Shuhei; Shinoda, Wataru, E-mail: w.shinoda@apchem.nagoya-u.ac.jp; Klein, Michael L.

The effects of membrane curvature on the free energy barrier for membrane fusion have been investigated using coarse-grained molecular dynamics (CG-MD) simulations, assuming that fusion takes place through a stalk intermediate. Free energy barriers were estimated for stalk formation as well as for fusion pore formation using the guiding potential method. Specifically, the three different geometries of two apposed membranes were considered: vesicle–vesicle, vesicle–planar, and planar–planar membranes. The free energy barriers for the resulting fusion were found to depend importantly on the fusing membrane geometries; the lowest barrier was obtained for vesicular membranes. Further, lipid sorting was observed in fusionmore » of the mixed membranes of dimyristoyl phosphatidylcholine and dioleoyl phosphatidylethanolamine (DOPE). Specifically, DOPE molecules were found to assemble around the stalk to support the highly negative curved membrane surface. A consistent result for lipid sorting was observed when a simple continuum model (CM) was used, where the Helfrich energy and mixing entropy of the lipids were taken into account. However, the CM predicts a much higher free energy barrier than found using CG-MD. This discrepancy originates from the conformational changes of lipids, which were not considered in the CM. The results of the CG-MD simulations reveal that a large conformational change in the lipid takes place around the stalk region, which results in a reduction of free energy barriers along the stalk mechanism of membrane fusion.« less

Integrated simulations of saturated neoclassical tearing modes in DIII-D, Joint European Torus, and ITER plasmas

DOE Office of Scientific and Technical Information (OSTI.GOV)

Halpern, Federico D.; Bateman, Glenn; Kritz, Arnold H.

2006-06-15

A revised version of the ISLAND module [C. N. Nguyen et al., Phys. Plasmas 11, 3604 (2004)] is used in the BALDUR code [C. E. Singer et al., Comput. Phys. Commun. 49, 275 (1988)] to carry out integrated modeling simulations of DIII-D [J. Luxon, Nucl. Fusion 42, 614 (2002)], Joint European Torus (JET) [P. H. Rebut et al., Nucl. Fusion 25, 1011 (1985)], and ITER [R. Aymar et al., Plasma Phys. Control. Fusion 44, 519 (2002)] tokamak discharges in order to investigate the adverse effects of multiple saturated magnetic islands driven by neoclassical tearing modes (NTMs). Simulations are carried outmore » with a predictive model for the temperature and density pedestal at the edge of the high confinement mode (H-mode) plasma and with core transport described using the Multi-Mode model. The ISLAND module, which is used to compute magnetic island widths, includes the effects of an arbitrary aspect ratio and plasma cross sectional shape, the effect of the neoclassical bootstrap current, and the effect of the distortion in the shape of each magnetic island caused by the radial variation of the perturbed magnetic field. Radial transport is enhanced across the width of each magnetic island within the BALDUR integrated modeling simulations in order to produce a self-consistent local flattening of the plasma profiles. It is found that the main consequence of the NTM magnetic islands is a decrease in the central plasma temperature and total energy. For the DIII-D and JET discharges, it is found that inclusion of the NTMs typically results in a decrease in total energy of the order of 15%. In simulations of ITER, it is found that the saturated magnetic island widths normalized by the plasma minor radius, for the lowest order individual tearing modes, are approximately 24% for the 2/1 mode and 12% for the 3/2 mode. As a result, the ratio of ITER fusion power to heating power (fusion Q) is reduced from Q=10.6 in simulations with no NTM islands to Q=2.6 in simulations with fully saturated NTM islands.« less

Lipid droplets fusion in adipocyte differentiated 3T3-L1 cells: A Monte Carlo simulation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boschi, Federico, E-mail: federico.boschi@univr.it; Department of Computer Science, University of Verona, Strada Le Grazie 15, 37134 Verona; Rizzatti, Vanni

Several human worldwide diseases like obesity, type 2 diabetes, hepatic steatosis, atherosclerosis and other metabolic pathologies are related to the excessive accumulation of lipids in cells. Lipids accumulate in spherical cellular inclusions called lipid droplets (LDs) whose sizes range from fraction to one hundred of micrometers in adipocytes. It has been suggested that LDs can grow in size due to a fusion process by which a larger LD is obtained with spherical shape and volume equal to the sum of the progenitors’ ones. In this study, the size distribution of two populations of LDs was analyzed in immature and maturemore » (5-days differentiated) 3T3-L1 adipocytes (first and second populations, respectively) after Oil Red O staining. A Monte Carlo simulation of interaction between LDs has been developed in order to quantify the size distribution and the number of fusion events needed to obtain the distribution of the second population size starting from the first one. Four models are presented here based on different kinds of interaction: a surface weighted interaction (R2 Model), a volume weighted interaction (R3 Model), a random interaction (Random model) and an interaction related to the place where the LDs are born (Nearest Model). The last two models mimic quite well the behavior found in the experimental data. This work represents a first step in developing numerical simulations of the LDs growth process. Due to the complex phenomena involving LDs (absorption, growth through additional neutral lipid deposition in existing droplets, de novo formation and catabolism) the study focuses on the fusion process. The results suggest that, to obtain the observed size distribution, a number of fusion events comparable with the number of LDs themselves is needed. Moreover the MC approach results a powerful tool for investigating the LDs growth process. Highlights: • We evaluated the role of the fusion process in the synthesis of the lipid droplets. • We compared the size distribution of the lipid droplets in immature and mature cells. • We used the Monte Carlo simulation approach, simulating 10 thousand of fusion events. • Four different interaction models between the lipid droplets were tested. • The best model which mimics the experimental measures was selected.« less

A Comparison of Coarse-Grained and Continuum Models for Membrane Bending in Lipid Bilayer Fusion Pores

PubMed Central

Yoo, Jejoong; Jackson, Meyer B.; Cui, Qiang

2013-01-01

To establish the validity of continuum mechanics models quantitatively for the analysis of membrane remodeling processes, we compare the shape and energies of the membrane fusion pore predicted by coarse-grained (MARTINI) and continuum mechanics models. The results at these distinct levels of resolution give surprisingly consistent descriptions for the shape of the fusion pore, and the deviation between the continuum and coarse-grained models becomes notable only when the radius of curvature approaches the thickness of a monolayer. Although slow relaxation beyond microseconds is observed in different perturbative simulations, the key structural features (e.g., dimension and shape of the fusion pore near the pore center) are consistent among independent simulations. These observations provide solid support for the use of coarse-grained and continuum models in the analysis of membrane remodeling. The combined coarse-grained and continuum analysis confirms the recent prediction of continuum models that the fusion pore is a metastable structure and that its optimal shape is neither toroidal nor catenoidal. Moreover, our results help reveal a new, to our knowledge, bowing feature in which the bilayers close to the pore axis separate more from one another than those at greater distances from the pore axis; bowing helps reduce the curvature and therefore stabilizes the fusion pore structure. The spread of the bilayer deformations over distances of hundreds of nanometers and the substantial reduction in energy of fusion pore formation provided by this spread indicate that membrane fusion can be enhanced by allowing a larger area of membrane to participate and be deformed. PMID:23442963

Multidirectional testing of one- and two-level ProDisc-L versus simulated fusions.

PubMed

Panjabi, Manohar; Henderson, Gweneth; Abjornson, Celeste; Yue, James

2007-05-20

An in vitro human cadaveric biomechanical study. To evaluate intervertebral rotation changes due to lumbar ProDisc-L compared with simulated fusion, using follower load and multidirectional testing. Artificial discs, as opposed to the fusions, are thought to decrease the long-term accelerated degeneration at adjacent levels. A biomechanical assessment can be helpful, as the long-term clinical evaluation is impractical. Six fresh human cadaveric lumbar specimens (T12-S1) underwent multidirectional testing in flexion-extension, bilateral lateral bending, and bilateral torsion using the Hybrid test method. First, intact specimen total range of rotation (T12-S1) was determined. Second, using pure moments again, this range of rotation was achieved in each of the 5 constructs: A) ProDisc-L at L5-S1; B) fusion at L5-S1; C) ProDisc-L at L4-L5 and fusion at L5-S1; D) ProDisc-L at L4-L5 and L5-S1; and E) 2-level fusion at L4-L5 to L5-S1. Significant changes in the intervertebral rotations due to each construct were determined at the operated and nonoperated levels using repeated measures single factor ANOVA and Bonferroni statistical tests (P < 0.05). Adjacent-level effects (ALEs) were defined as the percentage changes in intervertebral rotations at the nonoperated levels due to the constructs. One- and 2-level ProDisc-L constructs showed only small ALE in any of the 3 rotations. In contrast, 1- and 2-level fusions showed increased ALE in all 3 directions (average, 7.8% and 35.3%, respectively, for 1 and 2 levels). In the disc plus fusion combination (construct C), the ALEs were similar to the 1-level fusion alone. In general, ProDisc-L preserved physiologic motions at all spinal levels, while the fusion simulations resulted in significant ALE.

Finite Element Analysis of Interaction of Laser Beam with Material in Laser Metal Powder Bed Fusion Process.

PubMed

Fu, Guang; Zhang, David Z; He, Allen N; Mao, Zhongfa; Zhang, Kaifei

2018-05-10

A deep understanding of the laser-material interaction mechanism, characterized by laser absorption, is very important in simulating the laser metal powder bed fusion (PBF) process. This is because the laser absorption of material affects the temperature distribution, which influences the thermal stress development and the final quality of parts. In this paper, a three-dimensional finite element analysis model of heat transfer taking into account the effect of material state and phase changes on laser absorption is presented to gain insight into the absorption mechanism, and the evolution of instantaneous absorptance in the laser metal PBF process. The results showed that the instantaneous absorptance was significantly affected by the time of laser radiation, as well as process parameters, such as hatch space, scanning velocity, and laser power, which were consistent with the experiment-based findings. The applicability of this model to temperature simulation was demonstrated by a comparative study, wherein the peak temperature in fusion process was simulated in two scenarios, with and without considering the effect of material state and phase changes on laser absorption, and the simulated results in the two scenarios were then compared with experimental data respectively.

Simulating irradiation hardening in tungsten under fast neutron irradiation including Re production by transmutation

NASA Astrophysics Data System (ADS)

Huang, Chen-Hsi; Gilbert, Mark R.; Marian, Jaime

2018-02-01

Simulations of neutron damage under fusion energy conditions must capture the effects of transmutation, both in terms of accurate chemical inventory buildup as well as the physics of the interactions between transmutation elements and irradiation defect clusters. In this work, we integrate neutronics, primary damage calculations, molecular dynamics results, Re transmutation calculations, and stochastic cluster dynamics simulations to study neutron damage in single-crystal tungsten to mimic divertor materials. To gauge the accuracy and validity of the simulations, we first study the material response under experimental conditions at the JOYO fast reactor in Japan and the High Flux Isotope Reactor at Oak Ridge National Laboratory, for which measurements of cluster densities and hardening levels up to 2 dpa exist. We then provide calculations under expected DEMO fusion conditions. Several key mechanisms involving Re atoms and defect clusters are found to govern the accumulation of irradiation damage in each case. We use established correlations to translate damage accumulation into hardening increases and compare our results to the experimental measurements. We find hardening increases in excess of 5000 MPa in all cases, which casts doubts about the integrity of W-based materials under long-term fusion exposure.

Differences in 3D vs. 2D analysis in lumbar spinal fusion simulations.

PubMed

Hsu, Hung-Wei; Bashkuev, Maxim; Pumberger, Matthias; Schmidt, Hendrik

2018-04-27

Lumbar interbody fusion is currently the gold standard in treating patients with disc degeneration or segmental instability. Despite it having been used for several decades, the non-union rate remains high. A failed fusion is frequently attributed to an inadequate mechanical environment after instrumentation. Finite element (FE) models can provide insights into the mechanics of the fusion process. Previous fusion simulations using FE models showed that the geometries and material of the cage can greatly influence the fusion outcome. However, these studies used axisymmetric models which lacked realistic spinal geometries. Therefore, different modeling approaches were evaluated to understand the bone-formation process. Three FE models of the lumbar motion segment (L4-L5) were developed: 2D, Sym-3D and Nonsym-3D. The fusion process based on existing mechano-regulation algorithms using the FE simulations to evaluate the mechanical environment was then integrated into these models. In addition, the influence of different lordotic angles (5, 10 and 15°) was investigated. The volume of newly formed bone, the axial stiffness of the whole segment and bone distribution inside and surrounding the cage were evaluated. In contrast to the Nonsym-3D, the 2D and Sym-3D models predicted excessive bone formation prior to bridging (peak values with 36 and 9% higher than in equilibrium, respectively). The 3D models predicted a more uniform bone distribution compared to the 2D model. The current results demonstrate the crucial role of the realistic 3D geometry of the lumbar motion segment in predicting bone formation after lumbar spinal fusion. Copyright © 2018 Elsevier Ltd. All rights reserved.

Assessing the Performance of Sensor Fusion Methods: Application to Magnetic-Inertial-Based Human Body Tracking

PubMed Central

Ligorio, Gabriele; Bergamini, Elena; Pasciuto, Ilaria; Vannozzi, Giuseppe; Cappozzo, Aurelio; Sabatini, Angelo Maria

2016-01-01

Information from complementary and redundant sensors are often combined within sensor fusion algorithms to obtain a single accurate observation of the system at hand. However, measurements from each sensor are characterized by uncertainties. When multiple data are fused, it is often unclear how all these uncertainties interact and influence the overall performance of the sensor fusion algorithm. To address this issue, a benchmarking procedure is presented, where simulated and real data are combined in different scenarios in order to quantify how each sensor’s uncertainties influence the accuracy of the final result. The proposed procedure was applied to the estimation of the pelvis orientation using a waist-worn magnetic-inertial measurement unit. Ground-truth data were obtained from a stereophotogrammetric system and used to obtain simulated data. Two Kalman-based sensor fusion algorithms were submitted to the proposed benchmarking procedure. For the considered application, gyroscope uncertainties proved to be the main error source in orientation estimation accuracy for both tested algorithms. Moreover, although different performances were obtained using simulated data, these differences became negligible when real data were considered. The outcome of this evaluation may be useful both to improve the design of new sensor fusion methods and to drive the algorithm tuning process. PMID:26821027

Assessing the Performance of Sensor Fusion Methods: Application to Magnetic-Inertial-Based Human Body Tracking.

PubMed

Ligorio, Gabriele; Bergamini, Elena; Pasciuto, Ilaria; Vannozzi, Giuseppe; Cappozzo, Aurelio; Sabatini, Angelo Maria

2016-01-26

Information from complementary and redundant sensors are often combined within sensor fusion algorithms to obtain a single accurate observation of the system at hand. However, measurements from each sensor are characterized by uncertainties. When multiple data are fused, it is often unclear how all these uncertainties interact and influence the overall performance of the sensor fusion algorithm. To address this issue, a benchmarking procedure is presented, where simulated and real data are combined in different scenarios in order to quantify how each sensor's uncertainties influence the accuracy of the final result. The proposed procedure was applied to the estimation of the pelvis orientation using a waist-worn magnetic-inertial measurement unit. Ground-truth data were obtained from a stereophotogrammetric system and used to obtain simulated data. Two Kalman-based sensor fusion algorithms were submitted to the proposed benchmarking procedure. For the considered application, gyroscope uncertainties proved to be the main error source in orientation estimation accuracy for both tested algorithms. Moreover, although different performances were obtained using simulated data, these differences became negligible when real data were considered. The outcome of this evaluation may be useful both to improve the design of new sensor fusion methods and to drive the algorithm tuning process.

Fusing simulation and experiment: The effect of mutations on the structure and activity of the influenza fusion peptide

PubMed Central

Lousa, Diana; Pinto, Antónia R. T.; Victor, Bruno L.; Laio, Alessandro; Veiga, Ana S.; Castanho, Miguel A. R. B.; Soares, Cláudio M.

2016-01-01

During the infection process, the influenza fusion peptide (FP) inserts into the host membrane, playing a crucial role in the fusion process between the viral and host membranes. In this work we used a combination of simulation and experimental techniques to analyse the molecular details of this process, which are largely unknown. Although the FP structure has been obtained by NMR in detergent micelles, there is no atomic structure information in membranes. To answer this question, we performed bias-exchange metadynamics (BE-META) simulations, which showed that the lowest energy states of the membrane-inserted FP correspond to helical-hairpin conformations similar to that observed in micelles. BE-META simulations of the G1V, W14A, G12A/G13A and G4A/G8A/G16A/G20A mutants revealed that all the mutations affect the peptide’s free energy landscape. A FRET-based analysis showed that all the mutants had a reduced fusogenic activity relative to the WT, in particular the mutants G12A/G13A and G4A/G8A/G16A/G20A. According to our results, one of the major causes of the lower activity of these mutants is their lower membrane affinity, which results in a lower concentration of peptide in the bilayer. These findings contribute to a better understanding of the influenza fusion process and open new routes for future studies. PMID:27302370

Fusing simulation and experiment: The effect of mutations on the structure and activity of the influenza fusion peptide.

PubMed

Lousa, Diana; Pinto, Antónia R T; Victor, Bruno L; Laio, Alessandro; Veiga, Ana S; Castanho, Miguel A R B; Soares, Cláudio M

2016-06-15

During the infection process, the influenza fusion peptide (FP) inserts into the host membrane, playing a crucial role in the fusion process between the viral and host membranes. In this work we used a combination of simulation and experimental techniques to analyse the molecular details of this process, which are largely unknown. Although the FP structure has been obtained by NMR in detergent micelles, there is no atomic structure information in membranes. To answer this question, we performed bias-exchange metadynamics (BE-META) simulations, which showed that the lowest energy states of the membrane-inserted FP correspond to helical-hairpin conformations similar to that observed in micelles. BE-META simulations of the G1V, W14A, G12A/G13A and G4A/G8A/G16A/G20A mutants revealed that all the mutations affect the peptide's free energy landscape. A FRET-based analysis showed that all the mutants had a reduced fusogenic activity relative to the WT, in particular the mutants G12A/G13A and G4A/G8A/G16A/G20A. According to our results, one of the major causes of the lower activity of these mutants is their lower membrane affinity, which results in a lower concentration of peptide in the bilayer. These findings contribute to a better understanding of the influenza fusion process and open new routes for future studies.

Visiting Scholars Program

DTIC Science & Technology

2016-09-01

other associated grants. 15. SUBJECT TERMS SUNY Poly, STEM, Artificial Intelligence , Command and Control 16. SECURITY CLASSIFICATION OF: 17...neuromorphic system has the potential to be widely used in a high-efficiency artificial intelligence system. Simulation results have indicated that the...novel multiresolution fusion and advanced fusion performance evaluation tool for an Artificial Intelligence based natural language annotation engine for

Image fusion based on Bandelet and sparse representation

NASA Astrophysics Data System (ADS)

Zhang, Jiuxing; Zhang, Wei; Li, Xuzhi

2018-04-01

Bandelet transform could acquire geometric regular direction and geometric flow, sparse representation could represent signals with as little as possible atoms on over-complete dictionary, both of which could be used to image fusion. Therefore, a new fusion method is proposed based on Bandelet and Sparse Representation, to fuse Bandelet coefficients of multi-source images and obtain high quality fusion effects. The test are performed on remote sensing images and simulated multi-focus images, experimental results show that the performance of new method is better than tested methods according to objective evaluation indexes and subjective visual effects.

Kinetic Plasma and Turbulent Mix Studies using DT Plastic-shell Implosions with Shell-thickness and Pressure Variations

NASA Astrophysics Data System (ADS)

Kim, Y.; Herrmann, H. W.; Hoffman, N. M.; Schmitt, M. J.; Bradley, P. A.; Kagan, G.; Gales, S.; Horsfield, C. J.; Rubery, M.; Leatherland, A.; Gatu Johnson, M.; Glebov, V.; Seka, W.; Marshall, F.; Stoeckl, C.; Church, J.

2014-10-01

Kinetic plasma and turbulent mix effects on inertial confinement fusion have been studied using a series of DT-filled plastic-shell implosions at the OMEGA laser facility. Plastic capsules of 4 different shell thicknesses (7.4, 15, 20, 29 micron) were shot at 2 different fill pressures in order to vary the ion mean free path compared to the size of fuel region (i.e., Knudsen number). We varied the empirical Knudsen number by a factor of 25. Measurements were obtained from the burn-averaged ion temperature and fuel areal density. Preliminary results indicate that as the empirical Knudsen number increases, fusion performances (e.g., neutron yield) increasingly deviate from hydrodynamic simulations unless turbulent mix and ion kinetic terms (e.g., enhanced ion diffusion, viscosity, thermal conduction, as well as Knudsen-layer fusion reactivity reduction) are considered. We are developing two separate simulations: one is a reduced-ion-kinetics model and the other is turbulent mix model. Two simulation results will be compared with the experimental observables.

Temperature characteristics of fusion splicing Hollow Core Photonic Crystal Fiber by sinusoidal modulation CO2 laser

NASA Astrophysics Data System (ADS)

Fu, Guangwei; Li, Kuixing; Fu, Xinghu; Bi, Weihong

2013-07-01

During the fusion splicing Hollow Core Photonic Crystal Fiber (HC-PCF), the air-holes collapse easily due to the improper fusion duration time and optical power. To analyze the temperature characteristics of fusion splicing HC-PCF, a heating method by sinusoidal modulation CO2 laser has been proposed. In the sinusoidal modulation, the variation relationships among laser power, temperature difference and angular frequency are analyzed. The results show that the theoretical simulation is basically in accordance with the experimental data. Therefore, a low-loss fusion splicing can be achieved by modulating the CO2 laser frequency to avoid the air-holes collapse of HC-PCF. Further, the errors are also given.

Multi-Sensor Optimal Data Fusion Based on the Adaptive Fading Unscented Kalman Filter

PubMed Central

Gao, Bingbing; Hu, Gaoge; Gao, Shesheng; Gu, Chengfan

2018-01-01

This paper presents a new optimal data fusion methodology based on the adaptive fading unscented Kalman filter for multi-sensor nonlinear stochastic systems. This methodology has a two-level fusion structure: at the bottom level, an adaptive fading unscented Kalman filter based on the Mahalanobis distance is developed and serves as local filters to improve the adaptability and robustness of local state estimations against process-modeling error; at the top level, an unscented transformation-based multi-sensor optimal data fusion for the case of N local filters is established according to the principle of linear minimum variance to calculate globally optimal state estimation by fusion of local estimations. The proposed methodology effectively refrains from the influence of process-modeling error on the fusion solution, leading to improved adaptability and robustness of data fusion for multi-sensor nonlinear stochastic systems. It also achieves globally optimal fusion results based on the principle of linear minimum variance. Simulation and experimental results demonstrate the efficacy of the proposed methodology for INS/GNSS/CNS (inertial navigation system/global navigation satellite system/celestial navigation system) integrated navigation. PMID:29415509

Multi-Sensor Optimal Data Fusion Based on the Adaptive Fading Unscented Kalman Filter.

PubMed

Gao, Bingbing; Hu, Gaoge; Gao, Shesheng; Zhong, Yongmin; Gu, Chengfan

2018-02-06

This paper presents a new optimal data fusion methodology based on the adaptive fading unscented Kalman filter for multi-sensor nonlinear stochastic systems. This methodology has a two-level fusion structure: at the bottom level, an adaptive fading unscented Kalman filter based on the Mahalanobis distance is developed and serves as local filters to improve the adaptability and robustness of local state estimations against process-modeling error; at the top level, an unscented transformation-based multi-sensor optimal data fusion for the case of N local filters is established according to the principle of linear minimum variance to calculate globally optimal state estimation by fusion of local estimations. The proposed methodology effectively refrains from the influence of process-modeling error on the fusion solution, leading to improved adaptability and robustness of data fusion for multi-sensor nonlinear stochastic systems. It also achieves globally optimal fusion results based on the principle of linear minimum variance. Simulation and experimental results demonstrate the efficacy of the proposed methodology for INS/GNSS/CNS (inertial navigation system/global navigation satellite system/celestial navigation system) integrated navigation.

Developing DIII-D To Prepare For ITER And The Path To Fusion Energy

NASA Astrophysics Data System (ADS)

Buttery, Richard; Hill, David; Solomon, Wayne; Guo, Houyang; DIII-D Team

2017-10-01

DIII-D pursues the advancement of fusion energy through scientific understanding and discovery of solutions. Research targets two key goals. First, to prepare for ITER we must resolve how to use its flexible control tools to rapidly reach Q =10, and develop the scientific basis to interpret results from ITER for fusion projection. Second, we must determine how to sustain a high performance fusion core in steady state conditions, with minimal actuators and a plasma exhaust solution. DIII-D will target these missions with: (i) increased electron heating and balanced torque neutral beams to simulate burning plasma conditions (ii) new 3D coil arrays to resolve control of transients (iii) off axis current drive to study physics in steady state regimes (iv) divertors configurations to promote detachment with low upstream density (v) a reactor relevant wall to qualify materials and resolve physics in reactor-like conditions. With new diagnostics and leading edge simulation, this will position the US for success in ITER and a unique knowledge to accelerate the approach to fusion energy. Supported by the US DOE under DE-FC02-04ER54698.

Design and Analysis of a Data Fusion Scheme in Mobile Wireless Sensor Networks Based on Multi-Protocol Mobile Agents

PubMed Central

Wu, Chunxue; Wu, Wenliang; Wan, Caihua

2017-01-01

Sensors are increasingly used in mobile environments with wireless network connections. Multiple sensor types measure distinct aspects of the same event. Their measurements are then combined to produce integrated, reliable results. As the number of sensors in networks increases, low energy requirements and changing network connections complicate event detection and measurement. We present a data fusion scheme for use in mobile wireless sensor networks with high energy efficiency and low network delays, that still produces reliable results. In the first phase, we used a network simulation where mobile agents dynamically select the next hop migration node based on the stability parameter of the link, and perform the data fusion at the migration node. Agents use the fusion results to decide if it should return the fusion results to the processing center or continue to collect more data. In the second phase. The feasibility of data fusion at the node level is confirmed by an experimental design where fused data from color sensors show near-identical results to actual physical temperatures. These results are potentially important for new large-scale sensor network applications. PMID:29099793

H2LIFT: global navigation simulation ship tracking and WMD detection in the maritime domain

NASA Astrophysics Data System (ADS)

Wyffels, Kevin

2007-04-01

This paper presents initial results for a tracking simulation of multiple maritime vehicles for use in a data fusion program detecting Weapons of Mass Destruction (WMD). This simulation supports a fusion algorithm (H2LIFT) for collecting and analyzing data providing a heuristic analysis tool for detecting weapons of mass destruction in the maritime domain. Tools required to develop a navigational simulation fitting a set of project objectives are introduced for integration into the H2LIFT algorithm. Emphasis is placed on the specific requirements of the H2LIFT project, however the basic equations, algorithms, and methodologies can be used as tools in a variety of scenario simulations. Discussion will be focused on track modeling (e.g. position tracking of ships), navigational techniques, WMD detection, and simulation of these models using Matlab and Simulink. Initial results provide absolute ship position data for a given multi-ship maritime scenario with random generation of a given ship containing a WMD. Required coordinate systems, conversions between coordinate systems, Earth modeling techniques, and navigational conventions and techniques are introduced for development of the simulations.

Characterizing the Conformational Landscape of Flavivirus Fusion Peptides via Simulation and Experiment

PubMed Central

Marzinek, Jan K.; Lakshminarayanan, Rajamani; Goh, Eunice; Huber, Roland G.; Panzade, Sadhana; Verma, Chandra; Bond, Peter J.

2016-01-01

Conformational changes in the envelope proteins of flaviviruses help to expose the highly conserved fusion peptide (FP), a region which is critical to membrane fusion and host cell infection, and which represents a significant target for antiviral drugs and antibodies. In principle, extended timescale atomic-resolution simulations may be used to characterize the dynamics of such peptides. However, the resultant accuracy is critically dependent upon both the underlying force field and sufficient conformational sampling. In the present study, we report a comprehensive comparison of three simulation methods and four force fields comprising a total of more than 40 μs of sampling. Additionally, we describe the conformational landscape of the FP fold across all flavivirus family members. All investigated methods sampled conformations close to available X-ray structures, but exhibited differently populated ensembles. The best force field / sampling combination was sufficiently accurate to predict that the solvated peptide fold is less ordered than in the crystallographic state, which was subsequently confirmed via circular dichroism and spectrofluorometric measurements. Finally, the conformational landscape of a mutant incapable of membrane fusion was significantly shallower than wild-type variants, suggesting that dynamics should be considered when therapeutically targeting FP epitopes. PMID:26785994

Bringing global gyrokinetic turbulence simulations to the transport timescale using a multiscale approach

NASA Astrophysics Data System (ADS)

Parker, Jeffrey; Lodestro, Lynda; Told, Daniel; Merlo, Gabriele; Ricketson, Lee; Campos, Alejandro; Jenko, Frank; Hittinger, Jeffrey

2017-10-01

Predictive whole-device simulation models will play an increasingly important role in ensuring the success of fusion experiments and accelerating the development of fusion energy. In the core of tokamak plasmas, a separation of timescales between turbulence and transport makes a single direct simulation of both processes computationally expensive. We present the first demonstration of a multiple-timescale method coupling global gyrokinetic simulations with a transport solver to calculate the self-consistent, steady-state temperature profile. Initial results are highly encouraging, with the coupling method appearing robust to the difficult problem of turbulent fluctuations. The method holds potential for integrating first-principles turbulence simulations into whole-device models and advancing the understanding of global plasma behavior. Work supported by US DOE under Contract DE-AC52-07NA27344 and the Exascale Computing Project (17-SC-20-SC).

Probing the mechanism of fusion in a two-dimensional computer simulation.

PubMed Central

Chanturiya, Alexandr; Scaria, Puthurapamil; Kuksenok, Oleksandr; Woodle, Martin C

2002-01-01

A two-dimensional (2D) model of lipid bilayers was developed and used to investigate a possible role of membrane lateral tension in membrane fusion. We found that an increase of lateral tension in contacting monolayers of 2D analogs of liposomes and planar membranes could cause not only hemifusion, but also complete fusion when internal pressure is introduced in the model. With a certain set of model parameters it was possible to induce hemifusion-like structural changes by a tension increase in only one of the two contacting bilayers. The effect of lysolipids was modeled as an insertion of a small number of extra molecules into the cis or trans side of the interacting bilayers at different stages of simulation. It was found that cis insertion arrests fusion and trans insertion has no inhibitory effect on fusion. The possibility of protein participation in tension-driven fusion was tested in simulation, with one of two model liposomes containing a number of structures capable of reducing the area occupied by them in the outer monolayer. It was found that condensation of these structures was sufficient to produce membrane reorganization similar to that observed in simulations with "protein-free" bilayers. These data support the hypothesis that changes in membrane lateral tension may be responsible for fusion in both model phospholipid membranes and in biological protein-mediated fusion. PMID:12023230

Simulation of polyethylene glycol and calcium-mediated membrane fusion

NASA Astrophysics Data System (ADS)

Pannuzzo, Martina; De Jong, Djurre H.; Raudino, Antonio; Marrink, Siewert J.

2014-03-01

We report on the mechanism of membrane fusion mediated by polyethylene glycol (PEG) and Ca2+ by means of a coarse-grained molecular dynamics simulation approach. Our data provide a detailed view on the role of cations and polymer in modulating the interaction between negatively charged apposed membranes. The PEG chains cause a reduction of the inter-lamellar distance and cause an increase in concentration of divalent cations. When thermally driven fluctuations bring the membranes at close contact, a switch from cis to trans Ca2+-lipid complexes stabilizes a focal contact acting as a nucleation site for further expansion of the adhesion region. Flipping of lipid tails induces subsequent stalk formation. Together, our results provide a molecular explanation for the synergistic effect of Ca2+ and PEG on membrane fusion.

Simulation of the evolution of fused silica's surface defect during wet chemical etching

NASA Astrophysics Data System (ADS)

Liu, Taixiang; Yang, Ke; Li, Heyang; Yan, Lianghong; Yuan, Xiaodong; Yan, Hongwei

2017-08-01

Large high-power-laser facility is the basis for achieving inertial confinement fusion, one of whose missions is to make fusion energy usable in the near future. In the facility, fused silica optics plays an irreplaceable role to conduct extremely high-intensity laser to fusion capsule. But the surface defect of fused silica is a major obstacle limiting the output power of the large laser facility and likely resulting in the failure of ignition. To mitigate, or event to remove the surface defect, wet chemical etching has been developed as a practical way. However, how the surface defect evolves during wet chemical etching is still not clearly known so far. To address this problem, in this work, the three-dimensional model of surface defect is built and finite difference time domain (FDTD) method is developed to simulate the evolution of surface defect during etching. From the simulation, it is found that the surface defect will get smooth and result in the improvement of surface quality of fused silica after etching. Comparatively, surface defects (e.g. micro-crack, scratch, series of pinholes, etc.) of a typical fused silica at different etching time are experimentally measured. It can be seen that the simulation result agrees well with the result of experiment, indicating the FDTD method is valid for investigating the evolution of surface defect during etching. With the finding of FDTD simulation, one can optimize the treatment process of fused silica in practical etching or even to make the initial characterization of surface defect traceable.

A Matrix Pencil Algorithm Based Multiband Iterative Fusion Imaging Method

NASA Astrophysics Data System (ADS)

Zou, Yong Qiang; Gao, Xun Zhang; Li, Xiang; Liu, Yong Xiang

2016-01-01

Multiband signal fusion technique is a practicable and efficient way to improve the range resolution of ISAR image. The classical fusion method estimates the poles of each subband signal by the root-MUSIC method, and some good results were get in several experiments. However, this method is fragile in noise for the proper poles could not easy to get in low signal to noise ratio (SNR). In order to eliminate the influence of noise, this paper propose a matrix pencil algorithm based method to estimate the multiband signal poles. And to deal with mutual incoherent between subband signals, the incoherent parameters (ICP) are predicted through the relation of corresponding poles of each subband. Then, an iterative algorithm which aimed to minimize the 2-norm of signal difference is introduced to reduce signal fusion error. Applications to simulate dada verify that the proposed method get better fusion results at low SNR.

A Matrix Pencil Algorithm Based Multiband Iterative Fusion Imaging Method

PubMed Central

Zou, Yong Qiang; Gao, Xun Zhang; Li, Xiang; Liu, Yong Xiang

2016-01-01

Multiband signal fusion technique is a practicable and efficient way to improve the range resolution of ISAR image. The classical fusion method estimates the poles of each subband signal by the root-MUSIC method, and some good results were get in several experiments. However, this method is fragile in noise for the proper poles could not easy to get in low signal to noise ratio (SNR). In order to eliminate the influence of noise, this paper propose a matrix pencil algorithm based method to estimate the multiband signal poles. And to deal with mutual incoherent between subband signals, the incoherent parameters (ICP) are predicted through the relation of corresponding poles of each subband. Then, an iterative algorithm which aimed to minimize the 2-norm of signal difference is introduced to reduce signal fusion error. Applications to simulate dada verify that the proposed method get better fusion results at low SNR. PMID:26781194

Economics and Environmental Compatibility of Fusion Reactors —Its Analysis and Coming Issues— 1.Energy Strategy of the 21st Century Taking Advantage of Fusion

NASA Astrophysics Data System (ADS)

Okumura, Norihiro

There is some general concern that economic development in developing countries will hasten global warning. In terms of reducing CO2 emissions, fusion will have great potential as a primary energy in the late 21st century according to the results of WING model simulations based on scenario analysis, if the cost of fusion with hydrogen generation would become competitive compared with those of other substitutive energies. However, securing social acceptance is very important to maintain the fossil research funded by the government suffering from cumulative debt.

sUAS Position Estimation and Fusion in GPS-Degraded and GPS-Denied Environments using an ADS-B Transponder and Local Area Multilateration

NASA Astrophysics Data System (ADS)

Larson, Robert Sherman

An Unmanned Aerial Vehicle (UAV) and a manned aircraft are tracked using ADS-B transponders and the Local Area Multilateration System (LAMS) in simulated GPS-degraded and GPS-denied environments. Several position estimation and fusion algorithms are developed for use with the Autonomous Flight Systems Laboratory (AFSL) TRansponder based Position Information System (TRAPIS) software. At the lowest level, these estimation and fusion algorithms use raw information from ADS-B and LAMS data streams to provide aircraft position estimates to the ground station user. At the highest level, aircraft position is estimated using a discrete time Kalman filter with real-time covariance updates and fusion involving weighted averaging of ADS-B and LAMS positions. Simulation and flight test results are provided, demonstrating the feasibility of incorporating an ADS-B transponder on a commercially-available UAS and maintaining situational awareness of aircraft positions in GPS-degraded and GPS-denied environments.

Simulation studies of hydrodynamic aspects of magneto-inertial fusion and high order adaptive algorithms for Maxwell equations

NASA Astrophysics Data System (ADS)

Wu, Lingling

Three-dimensional simulations of the formation and implosion of plasma liners for the Plasma Jet Induced Magneto Inertial Fusion (PJMIF) have been performed using multiscale simulation technique based on the FronTier code. In the PJMIF concept, a plasma liner, formed by merging of a large number of radial, highly supersonic plasma jets, implodes on the target in the form of two compact plasma toroids, and compresses it to conditions of the nuclear fusion ignition. The propagation of a single jet with Mach number 60 from the plasma gun to the merging point was studied using the FronTier code. The simulation result was used as input to the 3D jet merger problem. The merger of 144, 125, and 625 jets and the formation and heating of plasma liner by compression waves have been studied and compared with recent theoretical predictions. The main result of the study is the prediction of the average Mach number reduction and the description of the liner structure and properties. We have also compared the effect of different merging radii. Spherically symmetric simulations of the implosion of plasma liners and compression of plasma targets have also been performed using the method of front tracking. The cases of single deuterium and xenon liners and double layer deuterium - xenon liners compressing various deuterium-tritium targets have been investigated, optimized for maximum fusion energy gains, and compared with theoretical predictions and scaling laws of [P. Parks, On the efficacy of imploding plasma liners for magnetized fusion target compression, Phys. Plasmas 15, 062506 (2008)]. In agreement with the theory, the fusion gain was significantly below unity for deuterium - tritium targets compressed by Mach 60 deuterium liners. In the most optimal setup for a given chamber size that contained a target with the initial radius of 20 cm compressed by 10 cm thick, Mach 60 xenon liner, the target ignition and fusion energy gain of 10 was achieved. Simulations also showed that composite deuterium - xenon liners reduce the energy gain due to lower target compression rates. The effect of heating of targets by alpha particles on the fusion energy gain has also been investigated. The study of the dependence of the ram pressure amplification on radial compressibility showed a good agreement with the theory. The study concludes that a liner with higher Mach number and lower adiabatic index gamma (the radio of specific heats) will generate higher ram pressure amplification and higher fusion energy gain. We implemented a second order embedded boundary method for the Maxwell equations in geometrically complex domains. The numerical scheme is second order in both space and time. Comparing to the first order stair-step approximation of complex geometries within the FDTD method, this method can avoid spurious solution introduced by the stair step approximation. Unlike the finite element method and the FE-FD hybrid method, no triangulation is needed for this scheme. This method preserves the simplicity of the embedded boundary method and it is easy to implement. We will also propose a conservative (symplectic) fourth order scheme for uniform geometry boundary.

Direct simulation of amphiphilic nanoparticle mediated membrane interactions

NASA Astrophysics Data System (ADS)

Tahir, Mukarram; Alexander-Katz, Alfredo

Membrane fusion is a critical step in the transport of biological cargo through membrane-bound compartments like vesicles. Membrane proteins that alleviate energy barriers for initial stalk formation and eventual rupture of the hemifusion intermediate during fusion generally assist this process. Gold nanoparticles functionalized with a combination of hydrophobic and hydrophilic alkanethiol ligands have recently been shown to induce membrane re-arrangements that are similar to those associated with these fusion proteins. In this work, we utilize molecular dynamics simulation to systematically design nanoparticles that exhibit targeted interactions with membranes. We introduce a method for rapidly parameterizing nanoparticle topology for the MARTINI biomolecular force field to permit long timescale simulation of their interactions with lipid bilayers. We leverage this model to investigate how ligand chemistry governs the nanoparticle's insertion efficacy and the perturbations it generates in the membrane environment. We further demonstrate through unbiased simulations that these nanoparticles can direct the fusion of lipid assemblies such as micelles and vesicles in a manner that mimics the function of biological fusion peptides and SNARE proteins.

Structure and function of photosystem I–[FeFe] hydrogenase protein fusions: An all-atom molecular dynamics study

DOE Office of Scientific and Technical Information (OSTI.GOV)

Harris, Bradley J.; Cheng, Xiaolin; Frymier, Paul

2015-12-15

All-atom molecular dynamics (MD) simulation was used to study the solution dynamics and protein protein interactions of protein fusions of photosystem I (PSI) from Thermosynechococcus elongatus and an [FeFe]-hydrogenase (FeFe H 2ase) from Clostridium pasteurianum, a unique complex capable of photocatalytic hydrogen production. This study involved fusions of these two proteins via dithiol linkers of different length including decanedithiol, octanedithiol, and hexanedithiol, for which experimental data had previously been obtained. Evaluation of root-mean-squared deviations (RMSDs) relative to the respective crystal structures of PSI and the FeFe H 2ase shows that these fusion complexes approach stable equilibrium conformations during the MDmore » simulations. Investigating protein mobility via root-mean-squared fluctuations (RMSFs) reveals that tethering via the shortest hexanedithiol linker results in increased atomic fluctuations of both PSI and the hydrogenase in these fusion complexes. Furthermore, evaluation of the inter- and intraprotein electron transfer distances in these fusion complexes indicates that the structural changes in the FeFe H 2ase arising from ligation to PSI via the shortest hexanedithiol linker may hinder electron transport in the hydrogenase, thus providing a molecular level explanation for the observation that the medium-length octanedithiol linker gives the highest hydrogen production rate.« less

Statistical algorithms improve accuracy of gene fusion detection

PubMed Central

Hsieh, Gillian; Bierman, Rob; Szabo, Linda; Lee, Alex Gia; Freeman, Donald E.; Watson, Nathaniel; Sweet-Cordero, E. Alejandro

2017-01-01

Abstract Gene fusions are known to play critical roles in tumor pathogenesis. Yet, sensitive and specific algorithms to detect gene fusions in cancer do not currently exist. In this paper, we present a new statistical algorithm, MACHETE (Mismatched Alignment CHimEra Tracking Engine), which achieves highly sensitive and specific detection of gene fusions from RNA-Seq data, including the highest Positive Predictive Value (PPV) compared to the current state-of-the-art, as assessed in simulated data. We show that the best performing published algorithms either find large numbers of fusions in negative control data or suffer from low sensitivity detecting known driving fusions in gold standard settings, such as EWSR1-FLI1. As proof of principle that MACHETE discovers novel gene fusions with high accuracy in vivo, we mined public data to discover and subsequently PCR validate novel gene fusions missed by other algorithms in the ovarian cancer cell line OVCAR3. These results highlight the gains in accuracy achieved by introducing statistical models into fusion detection, and pave the way for unbiased discovery of potentially driving and druggable gene fusions in primary tumors. PMID:28541529

Data fusion: principles and applications in air defense

NASA Astrophysics Data System (ADS)

Maltese, Dominique; Lucas, Andre

1998-07-01

Within a Surveillance and Reconnaissance System, the Fusion Process is an essential part of the software package since the different sensors measurements are combined by this process; each sensor sends its data to a fusion center whose task is to elaborate the best tactical situation. In this paper, a practical algorithm of data fusion applied to a military application context is presented; the case studied here is a medium-range surveillance situation featuring a dual-sensor platform which combines a surveillance Radar and an IRST; both sensors are collocated. The presented performances were obtained on validation scenarios via simulations performed by SAGEM with the ESSOR ('Environnement de Simulation de Senseurs Optroniques et Radar') multisensor simulation test bench.

Double Cluster Heads Model for Secure and Accurate Data Fusion in Wireless Sensor Networks

PubMed Central

Fu, Jun-Song; Liu, Yun

2015-01-01

Secure and accurate data fusion is an important issue in wireless sensor networks (WSNs) and has been extensively researched in the literature. In this paper, by combining clustering techniques, reputation and trust systems, and data fusion algorithms, we propose a novel cluster-based data fusion model called Double Cluster Heads Model (DCHM) for secure and accurate data fusion in WSNs. Different from traditional clustering models in WSNs, two cluster heads are selected after clustering for each cluster based on the reputation and trust system and they perform data fusion independently of each other. Then, the results are sent to the base station where the dissimilarity coefficient is computed. If the dissimilarity coefficient of the two data fusion results exceeds the threshold preset by the users, the cluster heads will be added to blacklist, and the cluster heads must be reelected by the sensor nodes in a cluster. Meanwhile, feedback is sent from the base station to the reputation and trust system, which can help us to identify and delete the compromised sensor nodes in time. Through a series of extensive simulations, we found that the DCHM performed very well in data fusion security and accuracy. PMID:25608211

Data fusion strategies for hazard detection and safe site selection for planetary and small body landings

NASA Astrophysics Data System (ADS)

Câmara, F.; Oliveira, J.; Hormigo, T.; Araújo, J.; Ribeiro, R.; Falcão, A.; Gomes, M.; Dubois-Matra, O.; Vijendran, S.

2015-06-01

This paper discusses the design and evaluation of data fusion strategies to perform tiered fusion of several heterogeneous sensors and a priori data. The aim is to increase robustness and performance of hazard detection and avoidance systems, while enabling safe planetary and small body landings anytime, anywhere. The focus is on Mars and asteroid landing mission scenarios and three distinct data fusion algorithms are introduced and compared. The first algorithm consists of a hybrid camera-LIDAR hazard detection and avoidance system, the H2DAS, in which data fusion is performed at both sensor-level data (reconstruction of the point cloud obtained with a scanning LIDAR using the navigation motion states and correcting the image for motion compensation using IMU data), feature-level data (concatenation of multiple digital elevation maps, obtained from consecutive LIDAR images, to achieve higher accuracy and resolution maps while enabling relative positioning) as well as decision-level data (fusing hazard maps from multiple sensors onto a single image space, with a single grid orientation and spacing). The second method presented is a hybrid reasoning fusion, the HRF, in which innovative algorithms replace the decision-level functions of the previous method, by combining three different reasoning engines—a fuzzy reasoning engine, a probabilistic reasoning engine and an evidential reasoning engine—to produce safety maps. Finally, the third method presented is called Intelligent Planetary Site Selection, the IPSIS, an innovative multi-criteria, dynamic decision-level data fusion algorithm that takes into account historical information for the selection of landing sites and a piloting function with a non-exhaustive landing site search capability, i.e., capable of finding local optima by searching a reduced set of global maps. All the discussed data fusion strategies and algorithms have been integrated, verified and validated in a closed-loop simulation environment. Monte Carlo simulation campaigns were performed for the algorithms performance assessment and benchmarking. The simulations results comprise the landing phases of Mars and Phobos landing mission scenarios.

Research on the use of data fusion technology to evaluate the state of electromechanical equipment

NASA Astrophysics Data System (ADS)

Lin, Lin

2018-04-01

Aiming at the problems of different testing information modes and the coexistence of quantitative and qualitative information in the state evaluation of electromechanical equipment, the paper proposes the use of data fusion technology to evaluate the state of electromechanical equipment. This paper introduces the state evaluation process of mechanical and electrical equipment in detail, uses the D-S evidence theory to fuse the decision-making layers of mechanical and electrical equipment state evaluation and carries out simulation tests. The simulation results show that it is feasible and effective to apply the data fusion technology to the state evaluation of the mechatronic equipment. After the multiple decision-making information provided by different evaluation methods are fused repeatedly and the useful information is extracted repeatedly, the fuzziness of judgment can be reduced and the state evaluation Credibility.

Laser heating challenges of high yield MagLIF targets

NASA Astrophysics Data System (ADS)

Slutz, Stephen; Sefkow, Adam; Vesey, Roger

2014-10-01

The MagLIF (Magnetized Liner Inertial Fusion) concept is predicted by numerical simulation to produce fusion yields of about 100 kJ, when driven by 25 MA from the existing Z accelerator [S. A. Slutz et al. Phys. Plasmas 17, 056303 (2010)] and much higher yields with future accelerators delivering higher currents [Slutz and Vesey PRL 108, 025003 (2012)]. The fuel must be heated before compression to obtain significant fusion yields due to the relatively slow implosion velocities (~ 100 km/s) of magnetically driven liners. Lasers provide a convenient means to accomplish this pre-compressional heating of the fusion fuel, but there are challenges. The laser must penetrate a foil covering the laser entrance hole and deposit 20-30 kJ within the ~1 cm length of the liner in fuel at 6-12 mg/cc. Such high densities could result in beam scattering due to refraction and laser plasma interactions. Numerical simulations of the laser heating process are presented, which indicate that energies as high as 30 kJ could be deposited in the fuel by using two laser pulses of different wavelengths. Simulations of this process will be presented as well of results for a MagLIF design for a potential new machine delivering 50 MA of current. Sandia is a multiprogram laboratory operated by Sandia Corporation, a Lockheed Martin Company, for the United States Department of Energy's National Nuclear Security Administration under Contract DE-AC04-94AL85000.

Modeling and numerical analysis of a magneto-inertial fusion concept with the target created through FRC merging

NASA Astrophysics Data System (ADS)

Li, Chenguang; Yang, Xianjun

2016-10-01

The Magnetized Plasma Fusion Reactor concept is proposed as a magneto-inertial fusion approach based on the target plasma created through the collision merging of two oppositely translating field reversed configuration plasmas, which is then compressed by the imploding liner driven by the pulsed-power driver. The target creation process is described by a two-dimensional magnetohydrodynamics model, resulting in the typical target parameters. The implosion process and the fusion reaction are modeled by a simple zero-dimensional model, taking into account the alpha particle heating and the bremsstrahlung radiation loss. The compression on the target can be 2D cylindrical or 2.4D with the additive axial contraction taken into account. The dynamics of the liner compression and fusion burning are simulated and the optimum fusion gain and the associated target parameters are predicted. The scientific breakeven could be achieved at the optimized conditions.

Predictive Simulation of Process Windows for Powder Bed Fusion Additive Manufacturing: Influence of the Powder Bulk Density.

PubMed

Rausch, Alexander M; Küng, Vera E; Pobel, Christoph; Markl, Matthias; Körner, Carolin

2017-09-22

The resulting properties of parts fabricated by powder bed fusion additive manufacturing processes are determined by their porosity, local composition, and microstructure. The objective of this work is to examine the influence of the stochastic powder bed on the process window for dense parts by means of numerical simulation. The investigations demonstrate the unique capability of simulating macroscopic domains in the range of millimeters with a mesoscopic approach, which resolves the powder bed and the hydrodynamics of the melt pool. A simulated process window reveals the influence of the stochastic powder layer. The numerical results are verified with an experimental process window for selective electron beam-melted Ti-6Al-4V. Furthermore, the influence of the powder bulk density is investigated numerically. The simulations predict an increase in porosity and surface roughness for samples produced with lower powder bulk densities. Due to its higher probability for unfavorable powder arrangements, the process stability is also decreased. This shrinks the actual parameter range in a process window for producing dense parts.

Predictive Simulation of Process Windows for Powder Bed Fusion Additive Manufacturing: Influence of the Powder Bulk Density

PubMed Central

Rausch, Alexander M.; Küng, Vera E.; Pobel, Christoph; Körner, Carolin

2017-01-01

The resulting properties of parts fabricated by powder bed fusion additive manufacturing processes are determined by their porosity, local composition, and microstructure. The objective of this work is to examine the influence of the stochastic powder bed on the process window for dense parts by means of numerical simulation. The investigations demonstrate the unique capability of simulating macroscopic domains in the range of millimeters with a mesoscopic approach, which resolves the powder bed and the hydrodynamics of the melt pool. A simulated process window reveals the influence of the stochastic powder layer. The numerical results are verified with an experimental process window for selective electron beam-melted Ti-6Al-4V. Furthermore, the influence of the powder bulk density is investigated numerically. The simulations predict an increase in porosity and surface roughness for samples produced with lower powder bulk densities. Due to its higher probability for unfavorable powder arrangements, the process stability is also decreased. This shrinks the actual parameter range in a process window for producing dense parts. PMID:28937633

Assessment of ion kinetic effects in shock-driven inertial confinement fusion implosions using fusion burn imaging

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rosenberg, M. J., E-mail: mros@lle.rochester.edu; Séguin, F. H.; Rinderknecht, H. G.

The significance and nature of ion kinetic effects in D{sup 3}He-filled, shock-driven inertial confinement fusion implosions are assessed through measurements of fusion burn profiles. Over this series of experiments, the ratio of ion-ion mean free path to minimum shell radius (the Knudsen number, N{sub K}) was varied from 0.3 to 9 in order to probe hydrodynamic-like to strongly kinetic plasma conditions; as the Knudsen number increased, hydrodynamic models increasingly failed to match measured yields, while an empirically-tuned, first-step model of ion kinetic effects better captured the observed yield trends [Rosenberg et al., Phys. Rev. Lett. 112, 185001 (2014)]. Here, spatiallymore » resolved measurements of the fusion burn are used to examine kinetic ion transport effects in greater detail, adding an additional dimension of understanding that goes beyond zero-dimensional integrated quantities to one-dimensional profiles. In agreement with the previous findings, a comparison of measured and simulated burn profiles shows that models including ion transport effects are able to better match the experimental results. In implosions characterized by large Knudsen numbers (N{sub K} ∼ 3), the fusion burn profiles predicted by hydrodynamics simulations that exclude ion mean free path effects are peaked far from the origin, in stark disagreement with the experimentally observed profiles, which are centrally peaked. In contrast, a hydrodynamics simulation that includes a model of ion diffusion is able to qualitatively match the measured profile shapes. Therefore, ion diffusion or diffusion-like processes are identified as a plausible explanation of the observed trends, though further refinement of the models is needed for a more complete and quantitative understanding of ion kinetic effects.« less

Assessment of ion kinetic effects in shock-driven inertial confinement fusion (ICF) implosions using fusion burn imaging

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rosenberg, M. J.; Séguin, F. H.; Amendt, P. A.

The significance and nature of ion kinetic effects in D³He-filled, shock-driven inertial confinement fusion implosions are assessed through measurements of fusion burn profiles. Over this series of experiments, the ratio of ion-ion mean free path to minimum shell radius (the Knudsen number, N K) was varied from 0.3 to 9 in order to probe hydrodynamic-like to strongly kinetic plasma conditions; as the Knudsen number increased, hydrodynamic models increasingly failed to match measured yields, while an empirically-tuned, first-step model of ion kinetic effects better captured the observed yield trends [Rosenberg et al., Phys. Rev. Lett. 112, 185001 (2014)]. Here, spatially resolvedmore » measurements of the fusion burn are used to examine kinetic ion transport effects in greater detail, adding an additional dimension of understanding that goes beyond zero-dimensional integrated quantities to one-dimensional profiles. In agreement with the previous findings, a comparison of measured and simulated burn profiles shows that models including ion transport effects are able to better match the experimental results. In implosions characterized by large Knudsen numbers (N K ~ 3), the fusion burn profiles predicted by hydrodynamics simulations that exclude ion mean free path effects are peaked far from the origin, in stark disagreement with the experimentally observed profiles, which are centrally peaked. In contrast, a hydrodynamics simulation that includes a model of ion diffusion is able to qualitatively match the measured profile shapes. Therefore, ion diffusion or diffusion-like processes are identified as a plausible explanation of the observed trends, though further refinement of the models is needed for a more complete and quantitative understanding of ion kinetic effects.« less

Assessment of ion kinetic effects in shock-driven inertial confinement fusion implosions using fusion burn imaging

NASA Astrophysics Data System (ADS)

Rosenberg, M. J.; Séguin, F. H.; Amendt, P. A.; Atzeni, S.; Rinderknecht, H. G.; Hoffman, N. M.; Zylstra, A. B.; Li, C. K.; Sio, H.; Gatu Johnson, M.; Frenje, J. A.; Petrasso, R. D.; Glebov, V. Yu.; Stoeckl, C.; Seka, W.; Marshall, F. J.; Delettrez, J. A.; Sangster, T. C.; Betti, R.; Wilks, S. C.; Pino, J.; Kagan, G.; Molvig, K.; Nikroo, A.

2015-06-01

The significance and nature of ion kinetic effects in D3He-filled, shock-driven inertial confinement fusion implosions are assessed through measurements of fusion burn profiles. Over this series of experiments, the ratio of ion-ion mean free path to minimum shell radius (the Knudsen number, NK) was varied from 0.3 to 9 in order to probe hydrodynamic-like to strongly kinetic plasma conditions; as the Knudsen number increased, hydrodynamic models increasingly failed to match measured yields, while an empirically-tuned, first-step model of ion kinetic effects better captured the observed yield trends [Rosenberg et al., Phys. Rev. Lett. 112, 185001 (2014)]. Here, spatially resolved measurements of the fusion burn are used to examine kinetic ion transport effects in greater detail, adding an additional dimension of understanding that goes beyond zero-dimensional integrated quantities to one-dimensional profiles. In agreement with the previous findings, a comparison of measured and simulated burn profiles shows that models including ion transport effects are able to better match the experimental results. In implosions characterized by large Knudsen numbers (NK ˜ 3), the fusion burn profiles predicted by hydrodynamics simulations that exclude ion mean free path effects are peaked far from the origin, in stark disagreement with the experimentally observed profiles, which are centrally peaked. In contrast, a hydrodynamics simulation that includes a model of ion diffusion is able to qualitatively match the measured profile shapes. Therefore, ion diffusion or diffusion-like processes are identified as a plausible explanation of the observed trends, though further refinement of the models is needed for a more complete and quantitative understanding of ion kinetic effects.

Assessment of ion kinetic effects in shock-driven inertial confinement fusion (ICF) implosions using fusion burn imaging

DOE PAGES

Rosenberg, M. J.; Séguin, F. H.; Amendt, P. A.; ...

2015-06-02

The significance and nature of ion kinetic effects in D³He-filled, shock-driven inertial confinement fusion implosions are assessed through measurements of fusion burn profiles. Over this series of experiments, the ratio of ion-ion mean free path to minimum shell radius (the Knudsen number, N K) was varied from 0.3 to 9 in order to probe hydrodynamic-like to strongly kinetic plasma conditions; as the Knudsen number increased, hydrodynamic models increasingly failed to match measured yields, while an empirically-tuned, first-step model of ion kinetic effects better captured the observed yield trends [Rosenberg et al., Phys. Rev. Lett. 112, 185001 (2014)]. Here, spatially resolvedmore » measurements of the fusion burn are used to examine kinetic ion transport effects in greater detail, adding an additional dimension of understanding that goes beyond zero-dimensional integrated quantities to one-dimensional profiles. In agreement with the previous findings, a comparison of measured and simulated burn profiles shows that models including ion transport effects are able to better match the experimental results. In implosions characterized by large Knudsen numbers (N K ~ 3), the fusion burn profiles predicted by hydrodynamics simulations that exclude ion mean free path effects are peaked far from the origin, in stark disagreement with the experimentally observed profiles, which are centrally peaked. In contrast, a hydrodynamics simulation that includes a model of ion diffusion is able to qualitatively match the measured profile shapes. Therefore, ion diffusion or diffusion-like processes are identified as a plausible explanation of the observed trends, though further refinement of the models is needed for a more complete and quantitative understanding of ion kinetic effects.« less

The fusion of satellite and UAV data: simulation of high spatial resolution band

NASA Astrophysics Data System (ADS)

Jenerowicz, Agnieszka; Siok, Katarzyna; Woroszkiewicz, Malgorzata; Orych, Agata

2017-10-01

Remote sensing techniques used in the precision agriculture and farming that apply imagery data obtained with sensors mounted on UAV platforms became more popular in the last few years due to the availability of low- cost UAV platforms and low- cost sensors. Data obtained from low altitudes with low- cost sensors can be characterised by high spatial and radiometric resolution but quite low spectral resolution, therefore the application of imagery data obtained with such technology is quite limited and can be used only for the basic land cover classification. To enrich the spectral resolution of imagery data acquired with low- cost sensors from low altitudes, the authors proposed the fusion of RGB data obtained with UAV platform with multispectral satellite imagery. The fusion is based on the pansharpening process, that aims to integrate the spatial details of the high-resolution panchromatic image with the spectral information of lower resolution multispectral or hyperspectral imagery to obtain multispectral or hyperspectral images with high spatial resolution. The key of pansharpening is to properly estimate the missing spatial details of multispectral images while preserving their spectral properties. In the research, the authors presented the fusion of RGB images (with high spatial resolution) obtained with sensors mounted on low- cost UAV platforms and multispectral satellite imagery with satellite sensors, i.e. Landsat 8 OLI. To perform the fusion of UAV data with satellite imagery, the simulation of the panchromatic bands from RGB data based on the spectral channels linear combination, was conducted. Next, for simulated bands and multispectral satellite images, the Gram-Schmidt pansharpening method was applied. As a result of the fusion, the authors obtained several multispectral images with very high spatial resolution and then analysed the spatial and spectral accuracies of processed images.

Versatile fusion source integrator AFSI for fast ion and neutron studies in fusion devices

NASA Astrophysics Data System (ADS)

Sirén, Paula; Varje, Jari; Äkäslompolo, Simppa; Asunta, Otto; Giroud, Carine; Kurki-Suonio, Taina; Weisen, Henri; JET Contributors, The

2018-01-01

ASCOT Fusion Source Integrator AFSI, an efficient tool for calculating fusion reaction rates and characterizing the fusion products, based on arbitrary reactant distributions, has been developed and is reported in this paper. Calculation of reactor-relevant D-D, D-T and D-3He fusion reactions has been implemented based on the Bosch-Hale fusion cross sections. The reactions can be calculated between arbitrary particle populations, including Maxwellian thermal particles and minority energetic particles. Reaction rate profiles, energy spectra and full 4D phase space distributions can be calculated for the non-isotropic reaction products. The code is especially suitable for integrated modelling in self-consistent plasma physics simulations as well as in the Serpent neutronics calculation chain. Validation of the model has been performed for neutron measurements at the JET tokamak and the code has been applied to predictive simulations in ITER.

Multispectral multisensor image fusion using wavelet transforms

USGS Publications Warehouse

Lemeshewsky, George P.

1999-01-01

Fusion techniques can be applied to multispectral and higher spatial resolution panchromatic images to create a composite image that is easier to interpret than the individual images. Wavelet transform-based multisensor, multiresolution fusion (a type of band sharpening) was applied to Landsat thematic mapper (TM) multispectral and coregistered higher resolution SPOT panchromatic images. The objective was to obtain increased spatial resolution, false color composite products to support the interpretation of land cover types wherein the spectral characteristics of the imagery are preserved to provide the spectral clues needed for interpretation. Since the fusion process should not introduce artifacts, a shift invariant implementation of the discrete wavelet transform (SIDWT) was used. These results were compared with those using the shift variant, discrete wavelet transform (DWT). Overall, the process includes a hue, saturation, and value color space transform to minimize color changes, and a reported point-wise maximum selection rule to combine transform coefficients. The performance of fusion based on the SIDWT and DWT was evaluated with a simulated TM 30-m spatial resolution test image and a higher resolution reference. Simulated imagery was made by blurring higher resolution color-infrared photography with the TM sensors' point spread function. The SIDWT based technique produced imagery with fewer artifacts and lower error between fused images and the full resolution reference. Image examples with TM and SPOT 10-m panchromatic illustrate the reduction in artifacts due to the SIDWT based fusion.

Simulations of carbon sputtering in fusion reactor divertor plates

DOE Office of Scientific and Technical Information (OSTI.GOV)

Marian, J; Zepeda-Ruiz, L A; Gilmer, G H

2005-10-03

The interaction of edge plasma with material surfaces raises key issues for the viability of the International Thermonuclear Reactor (ITER) and future fusion reactors, including heat-flux limits, net material erosion, and impurity production. After exposure of the graphite divertor plate to the plasma in a fusion device, an amorphous C/H layer forms. This layer contains 20-30 atomic percent D/T bonded to C. Subsequent D/T impingement on this layer produces a variety of hydrocarbons that are sputtered back into the sheath region. We present molecular dynamics (MD) simulations of D/T impacts on amorphous carbon layer as a function of ion energymore » and orientation, using the AIREBO potential. In particular, energies are varied between 10 and 150 eV to transition from chemical to physical sputtering. These results are used to quantify yield, hydrocarbon composition and eventual plasma contamination.« less

Synthetic Diagnostics Platform for Fusion Plasma and a Two-Dimensional Synthetic Electron Cyclotron Emission Imaging Code

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shi, Lei

Magnetic confinement fusion is one of the most promising approaches to achieve fusion energy. With the rapid increase of the computational power over the past decades, numerical simulation have become an important tool to study the fusion plasmas. Eventually, the numerical models will be used to predict the performance of future devices, such as the International Thermonuclear Experiment Reactor (ITER) or DEMO. However, the reliability of these models needs to be carefully validated against experiments before the results can be trusted. The validation between simulations and measurements is hard particularly because the quantities directly available from both sides are different.more » While the simulations have the information of the plasma quantities calculated explicitly, the measurements are usually in forms of diagnostic signals. The traditional way of making the comparison relies on the diagnosticians to interpret the measured signals as plasma quantities. The interpretation is in general very complicated and sometimes not even unique. In contrast, given the plasma quantities from the plasma simulations, we can unambiguously calculate the generation and propagation of the diagnostic signals. These calculations are called synthetic diagnostics, and they enable an alternate way to compare the simulation results with the measurements. In this dissertation, we present a platform for developing and applying synthetic diagnostic codes. Three diagnostics on the platform are introduced. The reflectometry and beam emission spectroscopy diagnostics measure the electron density, and the electron cyclotron emission diagnostic measures the electron temperature. The theoretical derivation and numerical implementation of a new two dimensional Electron cyclotron Emission Imaging code is discussed in detail. This new code has shown the potential to address many challenging aspects of the present ECE measurements, such as runaway electron effects, and detection of the cross phase between the electron temperature and density fluctuations.« less

Theory-based transport simulations of TFTR L-mode temperature profiles

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bateman, G.

1992-03-01

The temperature profiles from a selection of Tokamak Fusion Test Reactor (TFTR) L-mode discharges (17{ital th} {ital European} {ital Conference} {ital on} {ital Controlled} {ital Fusion} {ital and} {ital Plasma} {ital Heating}, Amsterdam, 1990 (EPS, Petit-Lancy, Switzerland, 1990, p. 114)) are simulated with the 1 (1)/(2) -D baldur transport code (Comput. Phys. Commun. {bold 49}, 275 (1988)) using a combination of theoretically derived transport models, called the Multi-Mode Model (Comments Plasma Phys. Controlled Fusion {bold 11}, 165 (1988)). The present version of the Multi-Mode Model consists of effective thermal diffusivities resulting from trapped electron modes and ion temperature gradient ({eta}{submore » {ital i}}) modes, which dominate in the core of the plasma, together with resistive ballooning modes, which dominate in the periphery. Within the context of this transport model and the TFTR simulations reported here, the scaling of confinement with heating power comes from the temperature dependence of the {eta}{sub {ital i}} and trapped electron modes, while the scaling with current comes mostly from resistive ballooning modes.« less

Disassembly time of deuterium-cluster-fusion plasma irradiated by an intense laser pulse.

PubMed

Bang, W

2015-07-01

Energetic deuterium ions from large deuterium clusters (>10nm diameter) irradiated by an intense laser pulse (>10(16)W/cm(2)) produce DD fusion neutrons for a time interval determined by the geometry of the resulting fusion plasma. We present an analytical solution of this time interval, the plasma disassembly time, for deuterium plasmas that are cylindrical in shape. Assuming a symmetrically expanding deuterium plasma, we calculate the expected fusion neutron yield and compare with an independent calculation of the yield using the concept of a finite confinement time at a fixed plasma density. The calculated neutron yields agree quantitatively with the available experimental data. Our one-dimensional simulations indicate that one could expect a tenfold increase in total neutron yield by magnetically confining a 10-keV deuterium fusion plasma for 10ns.

SU-E-T-656: Quantitative Analysis of Proton Boron Fusion Therapy (PBFT) in Various Conditions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yoon, D; Jung, J; Shin, H

2015-06-15

Purpose: Three alpha particles are concomitant of proton boron interaction, which can be used in radiotherapy applications. We performed simulation studies to determine the effectiveness of proton boron fusion therapy (PBFT) under various conditions. Methods: Boron uptake regions (BURs) of various widths and densities were implemented in Monte Carlo n-particle extended (MCNPX) simulation code. The effect of proton beam energy was considered for different BURs. Four simulation scenarios were designed to verify the effectiveness of integrated boost that was observed in the proton boron reaction. In these simulations, the effect of proton beam energy was determined for different physical conditions,more » such as size, location, and boron concentration. Results: Proton dose amplification was confirmed for all proton beam energies considered (< 96.62%). Based on the simulation results for different physical conditions, the threshold for the range in which proton dose amplification occurred was estimated as 0.3 cm. Effective proton boron reaction requires the boron concentration to be equal to or greater than 14.4 mg/g. Conclusion: We established the effects of the PBFT with various conditions by using Monte Carlo simulation. The results of our research can be used for providing a PBFT dose database.« less

Disc replacement adjacent to cervical fusion: a biomechanical comparison of hybrid construct versus two-level fusion.

PubMed

Lee, Michael J; Dumonski, Mark; Phillips, Frank M; Voronov, Leonard I; Renner, Susan M; Carandang, Gerard; Havey, Robert M; Patwardhan, Avinash G

2011-11-01

A cadaveric biomechanical study. To investigate the biomechanical behavior of the cervical spine after cervical total disc replacement (TDR) adjacent to a fusion as compared to a two-level fusion. There are concerns regarding the biomechanical effects of cervical fusion on the mobile motion segments. Although previous biomechanical studies have demonstrated that cervical disc replacement normalizes adjacent segment motion, there is a little information regarding the function of a cervical disc replacement adjacent to an anterior cervical decompression and fusion, a potentially common clinical application. Nine cadaveric cervical spines (C3-T1, age: 60.2 ± 3.5 years) were tested under load- and displacement-control testing. After intact testing, a simulated fusion was performed at C4-C5, followed by C6-C7. The simulated fusion was then reversed, and the response of TDR at C5-C6 was measured. A hybrid construct was then tested with the TDR either below or above a single-level fusion and contrasted with a simulated two-level fusion (C4-C6 and C5-C7). The external fixator device used to simulate fusion significantly reduced range of motion (ROM) at C4-C5 and C6-C7 by 74.7 ± 8.1% and 78.1 ± 11.5%, respectively (P < 0.05). Removal of the fusion construct restored the motion response of the spinal segments to their intact state. Arthroplasty performed at C5-C6 using the porous-coated motion disc prosthesis maintained the total flexion-extension ROM to the level of the intact controls when used as a stand-alone procedure or when implanted adjacent to a single-level fusion (P > 0.05). The location of the single-level fusion, whether above or below the arthroplasty, did not significantly affect the motion response of the arthroplasty in the hybrid construct. Performing a two-level fusion significantly increased the motion demands on the nonoperated segments as compared to a hybrid TDR-plus fusion construct when the spine was required to reach the same motion end points. The spine with a hybrid construct required significantly less extension moment than the spine with a two-level fusion to reach the same extension end point. The porous-coated motion cervical prosthesis restored the ROM of the treated level to the intact state. When the porous-coated motion prosthesis was used in a hybrid construct, the TDR response was not adversely affected. A hybrid construct seems to offer significant biomechanical advantages over two-level fusion in terms of reducing compensatory adjacent-level hypermobility and also loads required to achieve a predetermined ROM.

Overview of the Fusion Z-Pinch Experiment FuZE

NASA Astrophysics Data System (ADS)

Weber, T. R.; Shumlak, U.; Nelson, B. A.; Golingo, R. P.; Claveau, E. L.; McLean, H. S.; Tummel, K. K.; Higginson, D. P.; Schmidt, A. E.; UW/LLNL Team

2016-10-01

Previously, the ZaP device, at the University of Washington, demonstrated sheared flow stabilized (SFS) Z-pinch plasmas. Instabilities that have historically plagued Z-pinch plasma confinement were mitigated using sheared flows generated from a coaxial plasma gun of the Marshall type. Based on these results, a new SFS Z-pinch experiment, the Fusion Z-pinch Experiment (FuZE), has been constructed. FuZE is designed to investigate the scaling of SFS Z-pinch plasmas towards fusion conditions. The experiment will be supported by high fidelity physics modeling using kinetic and fluid simulations. Initial plans are in place for a pulsed fusion reactor following the results of FuZE. Notably, the design relies on proven commercial technologies, including a modest discharge current (1.5 MA) and voltage (40 kV), and liquid metal electrodes. Supported by DoE FES, NNSA, and ARPA-E ALPHA.

Overview of the FuZE Fusion Z-Pinch Experiment

NASA Astrophysics Data System (ADS)

Shumlak, U.; Nelson, B. A.; Claveau, E. L.; Forbes, E. G.; Golingo, R. P.; Stepanov, A. D.; Weber, T. R.; Zhang, Y.; McLean, H. S.; Higginson, D. P.; Schmidt, A.; Tummel, K. K.

2017-10-01

Successful results of the sheared flow stabilized (SFS) Z-pinch from ZaP and ZaP-HD have motivated the new FuZE project to scale the plasma performance to fusion conditions. The SFS Z-pinch is immune to the instabilities that plague the conventional Z-pinch yet maintains the same favorable radial scaling. The plasma density and temperature increase rapidly with decreasing plasma radius, which naturally leads to a compact configuration at fusion conditions. The SFS Z-pinch is being investigated as a novel approach to a compact fusion device in a collaborative ARPA-E ALPHA project with the University of Washington and Lawrence Livermore National Laboratory. The project includes an experimental effort coupled with high-fidelity physics modeling using kinetic and fluid simulations. Along with scaling law analysis, computational and experimental results from the FuZE device are presented. This work is supported by an award from US ARPA-E.

A resilient and efficient CFD framework: Statistical learning tools for multi-fidelity and heterogeneous information fusion

NASA Astrophysics Data System (ADS)

Lee, Seungjoon; Kevrekidis, Ioannis G.; Karniadakis, George Em

2017-09-01

Exascale-level simulations require fault-resilient algorithms that are robust against repeated and expected software and/or hardware failures during computations, which may render the simulation results unsatisfactory. If each processor can share some global information about the simulation from a coarse, limited accuracy but relatively costless auxiliary simulator we can effectively fill-in the missing spatial data at the required times by a statistical learning technique - multi-level Gaussian process regression, on the fly; this has been demonstrated in previous work [1]. Based on the previous work, we also employ another (nonlinear) statistical learning technique, Diffusion Maps, that detects computational redundancy in time and hence accelerate the simulation by projective time integration, giving the overall computation a "patch dynamics" flavor. Furthermore, we are now able to perform information fusion with multi-fidelity and heterogeneous data (including stochastic data). Finally, we set the foundations of a new framework in CFD, called patch simulation, that combines information fusion techniques from, in principle, multiple fidelity and resolution simulations (and even experiments) with a new adaptive timestep refinement technique. We present two benchmark problems (the heat equation and the Navier-Stokes equations) to demonstrate the new capability that statistical learning tools can bring to traditional scientific computing algorithms. For each problem, we rely on heterogeneous and multi-fidelity data, either from a coarse simulation of the same equation or from a stochastic, particle-based, more "microscopic" simulation. We consider, as such "auxiliary" models, a Monte Carlo random walk for the heat equation and a dissipative particle dynamics (DPD) model for the Navier-Stokes equations. More broadly, in this paper we demonstrate the symbiotic and synergistic combination of statistical learning, domain decomposition, and scientific computing in exascale simulations.

Statistical image quantification toward optimal scan fusion and change quantification

NASA Astrophysics Data System (ADS)

Potesil, Vaclav; Zhou, Xiang Sean

2007-03-01

Recent advance of imaging technology has brought new challenges and opportunities for automatic and quantitative analysis of medical images. With broader accessibility of more imaging modalities for more patients, fusion of modalities/scans from one time point and longitudinal analysis of changes across time points have become the two most critical differentiators to support more informed, more reliable and more reproducible diagnosis and therapy decisions. Unfortunately, scan fusion and longitudinal analysis are both inherently plagued with increased levels of statistical errors. A lack of comprehensive analysis by imaging scientists and a lack of full awareness by physicians pose potential risks in clinical practice. In this paper, we discuss several key error factors affecting imaging quantification, studying their interactions, and introducing a simulation strategy to establish general error bounds for change quantification across time. We quantitatively show that image resolution, voxel anisotropy, lesion size, eccentricity, and orientation are all contributing factors to quantification error; and there is an intricate relationship between voxel anisotropy and lesion shape in affecting quantification error. Specifically, when two or more scans are to be fused at feature level, optimal linear fusion analysis reveals that scans with voxel anisotropy aligned with lesion elongation should receive a higher weight than other scans. As a result of such optimal linear fusion, we will achieve a lower variance than naïve averaging. Simulated experiments are used to validate theoretical predictions. Future work based on the proposed simulation methods may lead to general guidelines and error lower bounds for quantitative image analysis and change detection.

Fusion Simulation Program Definition. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cary, John R.

2012-09-05

We have completed our contributions to the Fusion Simulation Program Definition Project. Our contributions were in the overall planning with concentration in the definition of the area of Software Integration and Support. We contributed to the planning of multiple meetings, and we contributed to multiple planning documents.

Data Fusion Analysis for Range Test Validation System

DTIC Science & Technology

2010-07-14

simulants were released during the RTVS ’08 test series: triethyl phosphate (TEP), methyl salicylate (MeS), and acetic acid (AA). A total of 29 release...the combination of a grid of point sensors at ground level and a standoff FTIR system monitoring above ground areas proved effective in detecting the...presence of simulants over the test grid. A Dempster-Shafer approach for data fusion was selected as the most effective strategy for RTVS data fusion

Dynamics simulations for engineering macromolecular interactions

NASA Astrophysics Data System (ADS)

Robinson-Mosher, Avi; Shinar, Tamar; Silver, Pamela A.; Way, Jeffrey

2013-06-01

The predictable engineering of well-behaved transcriptional circuits is a central goal of synthetic biology. The artificial attachment of promoters to transcription factor genes usually results in noisy or chaotic behaviors, and such systems are unlikely to be useful in practical applications. Natural transcriptional regulation relies extensively on protein-protein interactions to insure tightly controlled behavior, but such tight control has been elusive in engineered systems. To help engineer protein-protein interactions, we have developed a molecular dynamics simulation framework that simplifies features of proteins moving by constrained Brownian motion, with the goal of performing long simulations. The behavior of a simulated protein system is determined by summation of forces that include a Brownian force, a drag force, excluded volume constraints, relative position constraints, and binding constraints that relate to experimentally determined on-rates and off-rates for chosen protein elements in a system. Proteins are abstracted as spheres. Binding surfaces are defined radially within a protein. Peptide linkers are abstracted as small protein-like spheres with rigid connections. To address whether our framework could generate useful predictions, we simulated the behavior of an engineered fusion protein consisting of two 20 000 Da proteins attached by flexible glycine/serine-type linkers. The two protein elements remained closely associated, as if constrained by a random walk in three dimensions of the peptide linker, as opposed to showing a distribution of distances expected if movement were dominated by Brownian motion of the protein domains only. We also simulated the behavior of fluorescent proteins tethered by a linker of varying length, compared the predicted Förster resonance energy transfer with previous experimental observations, and obtained a good correspondence. Finally, we simulated the binding behavior of a fusion of two ligands that could simultaneously bind to distinct cell-surface receptors, and explored the landscape of linker lengths and stiffnesses that could enhance receptor binding of one ligand when the other ligand has already bound to its receptor, thus, addressing potential mechanisms for improving targeted signal transduction proteins. These specific results have implications for the design of targeted fusion proteins and artificial transcription factors involving fusion of natural domains. More broadly, the simulation framework described here could be extended to include more detailed system features such as non-spherical protein shapes and electrostatics, without requiring detailed, computationally expensive specifications. This framework should be useful in predicting behavior of engineered protein systems including binding and dissociation reactions.

Dynamics simulations for engineering macromolecular interactions.

PubMed

Robinson-Mosher, Avi; Shinar, Tamar; Silver, Pamela A; Way, Jeffrey

2013-06-01

The predictable engineering of well-behaved transcriptional circuits is a central goal of synthetic biology. The artificial attachment of promoters to transcription factor genes usually results in noisy or chaotic behaviors, and such systems are unlikely to be useful in practical applications. Natural transcriptional regulation relies extensively on protein-protein interactions to insure tightly controlled behavior, but such tight control has been elusive in engineered systems. To help engineer protein-protein interactions, we have developed a molecular dynamics simulation framework that simplifies features of proteins moving by constrained Brownian motion, with the goal of performing long simulations. The behavior of a simulated protein system is determined by summation of forces that include a Brownian force, a drag force, excluded volume constraints, relative position constraints, and binding constraints that relate to experimentally determined on-rates and off-rates for chosen protein elements in a system. Proteins are abstracted as spheres. Binding surfaces are defined radially within a protein. Peptide linkers are abstracted as small protein-like spheres with rigid connections. To address whether our framework could generate useful predictions, we simulated the behavior of an engineered fusion protein consisting of two 20,000 Da proteins attached by flexible glycine/serine-type linkers. The two protein elements remained closely associated, as if constrained by a random walk in three dimensions of the peptide linker, as opposed to showing a distribution of distances expected if movement were dominated by Brownian motion of the protein domains only. We also simulated the behavior of fluorescent proteins tethered by a linker of varying length, compared the predicted Förster resonance energy transfer with previous experimental observations, and obtained a good correspondence. Finally, we simulated the binding behavior of a fusion of two ligands that could simultaneously bind to distinct cell-surface receptors, and explored the landscape of linker lengths and stiffnesses that could enhance receptor binding of one ligand when the other ligand has already bound to its receptor, thus, addressing potential mechanisms for improving targeted signal transduction proteins. These specific results have implications for the design of targeted fusion proteins and artificial transcription factors involving fusion of natural domains. More broadly, the simulation framework described here could be extended to include more detailed system features such as non-spherical protein shapes and electrostatics, without requiring detailed, computationally expensive specifications. This framework should be useful in predicting behavior of engineered protein systems including binding and dissociation reactions.

Simulation of defects in fusion plasma first wall materials

NASA Astrophysics Data System (ADS)

T, Troev; N, Nankov; T, Yoshiie

2014-06-01

Numerical calculations of radiation damages in beryllium, alpha-iron and tungsten irradiated by fusion neutrons were performed using molecular dynamics (MD) simulations. The displacement cascades efficiency has been calculated using the Norgett-Robinson-Torrens (NRT) formula, the universal pair-potential of Ziegler-Biersack-Littmark (ZBL) and the EAM inter-atomic potential. The pair potential overestimates the defects production by a factor of 2. The ZBL pair potential results and the EAM are comparable at higher primary knock-on atom (PKA) energies (E > 100 keV). We found that the most common types of defects are single vacancies, di-vacancies, interstitials and small number of interstitial clusters. On the bases of calculated results, the behavior of vacancies, empty nano-voids and nano-voids with hydrogen and helium were discussed.

Modeling and analysis of tritium dynamics in a DT fusion fuel cycle

NASA Astrophysics Data System (ADS)

Kuan, William

1998-11-01

A number of crucial design issues have a profound effect on the dynamics of the tritium fuel cycle in a DT fusion reactor, where the development of appropriate solutions to these issues is of particular importance to the introduction of fusion as a commercial system. Such tritium-related issues can be classified according to their operational, safety, and economic impact to the operation of the reactor during its lifetime. Given such key design issues inherent in next generation fusion devices using the DT fuel cycle development of appropriate models can then lead to optimized designs of the fusion fuel cycle for different types of DT fusion reactors. In this work, two different types of modeling approaches are developed and their application to solving key tritium issues presented. For the first approach, time-dependent inventories, concentrations, and flow rates characterizing the main subsystems of the fuel cycle are simulated with a new dynamic modular model of a fusion reactor's fuel cycle, named X-TRUFFLES (X-Windows TRitiUm Fusion Fuel cycLE dynamic Simulation). The complex dynamic behavior of the recycled fuel within each of the modeled subsystems is investigated using this new integrated model for different reactor scenarios and design approaches. Results for a proposed fuel cycle design taking into account current technologies are presented, including sensitivity studies. Ways to minimize the tritium inventory are also assessed by examining various design options that could be used to minimize local and global tritium inventories. The second modeling approach involves an analytical model to be used for the calculation of the required tritium breeding ratio, i.e., a primary design issue which relates directly to the feasibility and economics of DT fusion systems. A time-integrated global tritium balance scheme is developed and appropriate analytical expressions are derived for tritium self-sufficiency relevant parameters. The easy exploration of the large parameter space of the fusion fuel cycle can thus be conducted as opposed to previous modeling approaches. Future guidance for R&D (research and development) in fusion nuclear technology is discussed in view of possible routes to take in reducing the tritium breeding requirements of DT fusion reactors.

Ion distribution in the hot spot of an inertial confinement fusion plasma

NASA Astrophysics Data System (ADS)

Tang, Xianzhu; Guo, Zehua; Berk, Herb

2012-10-01

Maximizing the fusion gain of inertial confinement fusion (ICF) for inertial fusion energy (IFE) applications leads to the standard scenario of central hot spot ignition followed by propagating burn wave through the cold/dense assembled fuel. The fact that the hot spot is surrounded by cold but dense fuel layer introduces subtle plasma physics which requires a kinetic description. Here we perform Fokker-Planck calculations and kinetic PIC simulations for an ICF plasma initially in pressure balance but having large temperature gradient over a narrow transition layer. The loss of the fast ion tail from the hot spot, which is important for fusion reactivity, is quantified by Fokker-Planck models. The role of electron energy transport and the ambipolar electric field is investigated via kinetic simulations and the fluid moment models. The net effect on both hot spot ion temperature and the ion tail distribution, and hence the fusion reactivity, is elucidated.

Multi-scale gyrokinetic simulations of an Alcator C-Mod, ELM-y H-mode plasma

NASA Astrophysics Data System (ADS)

Howard, N. T.; Holland, C.; White, A. E.; Greenwald, M.; Rodriguez-Fernandez, P.; Candy, J.; Creely, A. J.

2018-01-01

High fidelity, multi-scale gyrokinetic simulations capable of capturing both ion ({k}θ {ρ }s∼ { O }(1.0)) and electron-scale ({k}θ {ρ }e∼ { O }(1.0)) turbulence were performed in the core of an Alcator C-Mod ELM-y H-mode discharge which exhibits reactor-relevant characteristics. These simulations, performed with all experimental inputs and realistic ion to electron mass ratio ({({m}i/{m}e)}1/2=60.0) provide insight into the physics fidelity that may be needed for accurate simulation of the core of fusion reactor discharges. Three multi-scale simulations and series of separate ion and electron-scale simulations performed using the GYRO code (Candy and Waltz 2003 J. Comput. Phys. 186 545) are presented. As with earlier multi-scale results in L-mode conditions (Howard et al 2016 Nucl. Fusion 56 014004), both ion and multi-scale simulations results are compared with experimentally inferred ion and electron heat fluxes, as well as the measured values of electron incremental thermal diffusivities—indicative of the experimental electron temperature profile stiffness. Consistent with the L-mode results, cross-scale coupling is found to play an important role in the simulation of these H-mode conditions. Extremely stiff ion-scale transport is observed in these high-performance conditions which is shown to likely play and important role in the reproduction of measurements of perturbative transport. These results provide important insight into the role of multi-scale plasma turbulence in the core of reactor-relevant plasmas and establish important constraints on the the fidelity of models needed for predictive simulations.

Properties of ecosystems that are vulnerable during eco-fusion

PubMed Central

Yoshida, Katsuhiko; Tokita, Kei

2015-01-01

When two ecosystems with separate evolutionary histories come into contact (eco-fusion), reciprocal invasions occur during their fusion. Asymmetries in the migration direction or extinction rate then occur (e.g., during the Great American Biotic Interchange, GABI). Hypotheses have been proposed to describe this process, but the ecosystem properties have not been adequately discussed. To identify the ecosystem properties that create vulnerability to species loss during eco-fusion, we conducted computer simulations of the fusion of ecosystems with independent evolutionary histories. With asymmetrical species extinction rates, the ecosystem with a higher extinction rate had a shorter food chain, a higher ratio of animal species to plant species, and a lower ratio of carnivores to herbivores. Most ecosystems that have undergone isolated evolution are vulnerable. These results may explain the vulnerability of South America's ecosystem during the GABI and that of modern Australia. PMID:25631294

An Innovative Thinking-Based Intelligent Information Fusion Algorithm

PubMed Central

Hu, Liang; Liu, Gang; Zhou, Jin

2013-01-01

This study proposes an intelligent algorithm that can realize information fusion in reference to the relative research achievements in brain cognitive theory and innovative computation. This algorithm treats knowledge as core and information fusion as a knowledge-based innovative thinking process. Furthermore, the five key parts of this algorithm including information sense and perception, memory storage, divergent thinking, convergent thinking, and evaluation system are simulated and modeled. This algorithm fully develops innovative thinking skills of knowledge in information fusion and is a try to converse the abstract conception of brain cognitive science to specific and operable research routes and strategies. Furthermore, the influences of each parameter of this algorithm on algorithm performance are analyzed and compared with those of classical intelligent algorithms trough test. Test results suggest that the algorithm proposed in this study can obtain the optimum problem solution by less target evaluation times, improve optimization effectiveness, and achieve the effective fusion of information. PMID:23956699

An innovative thinking-based intelligent information fusion algorithm.

PubMed

Lu, Huimin; Hu, Liang; Liu, Gang; Zhou, Jin

2013-01-01

This study proposes an intelligent algorithm that can realize information fusion in reference to the relative research achievements in brain cognitive theory and innovative computation. This algorithm treats knowledge as core and information fusion as a knowledge-based innovative thinking process. Furthermore, the five key parts of this algorithm including information sense and perception, memory storage, divergent thinking, convergent thinking, and evaluation system are simulated and modeled. This algorithm fully develops innovative thinking skills of knowledge in information fusion and is a try to converse the abstract conception of brain cognitive science to specific and operable research routes and strategies. Furthermore, the influences of each parameter of this algorithm on algorithm performance are analyzed and compared with those of classical intelligent algorithms trough test. Test results suggest that the algorithm proposed in this study can obtain the optimum problem solution by less target evaluation times, improve optimization effectiveness, and achieve the effective fusion of information.

Disassembly time of deuterium-cluster-fusion plasma irradiated by an intense laser pulse

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bang, W.

Energetic deuterium ions from large deuterium clusters (>10 nm diameter) irradiated by an intense laser pulse (>10¹⁶ W/cm²) produce DD fusion neutrons for a time interval determined by the geometry of the resulting fusion plasma. We show an analytical solution of this time interval, the plasma disassembly time, for deuterium plasmas that are cylindrical in shape. Assuming a symmetrically expanding deuterium plasma, we calculate the expected fusion neutron yield and compare with an independent calculation of the yield using the concept of a finite confinement time at a fixed plasma density. The calculated neutron yields agree quantitatively with the availablemore » experimental data. Our one-dimensional simulations indicate that one could expect a tenfold increase in total neutron yield by magnetically confining a 10 - keV deuterium fusion plasma for 10 ns.« less

Disassembly time of deuterium-cluster-fusion plasma irradiated by an intense laser pulse

DOE PAGES

Bang, W.

2015-07-02

Energetic deuterium ions from large deuterium clusters (>10 nm diameter) irradiated by an intense laser pulse (>10¹⁶ W/cm²) produce DD fusion neutrons for a time interval determined by the geometry of the resulting fusion plasma. We show an analytical solution of this time interval, the plasma disassembly time, for deuterium plasmas that are cylindrical in shape. Assuming a symmetrically expanding deuterium plasma, we calculate the expected fusion neutron yield and compare with an independent calculation of the yield using the concept of a finite confinement time at a fixed plasma density. The calculated neutron yields agree quantitatively with the availablemore » experimental data. Our one-dimensional simulations indicate that one could expect a tenfold increase in total neutron yield by magnetically confining a 10 - keV deuterium fusion plasma for 10 ns.« less

Computational Intelligence for Medical Imaging Simulations.

PubMed

Chang, Victor

2017-11-25

This paper describes how to simulate medical imaging by computational intelligence to explore areas that cannot be easily achieved by traditional ways, including genes and proteins simulations related to cancer development and immunity. This paper has presented simulations and virtual inspections of BIRC3, BIRC6, CCL4, KLKB1 and CYP2A6 with their outputs and explanations, as well as brain segment intensity due to dancing. Our proposed MapReduce framework with the fusion algorithm can simulate medical imaging. The concept is very similar to the digital surface theories to simulate how biological units can get together to form bigger units, until the formation of the entire unit of biological subject. The M-Fusion and M-Update function by the fusion algorithm can achieve a good performance evaluation which can process and visualize up to 40 GB of data within 600 s. We conclude that computational intelligence can provide effective and efficient healthcare research offered by simulations and visualization.

International strategy for fusion materials development

NASA Astrophysics Data System (ADS)

Ehrlich, Karl; Bloom, E. E.; Kondo, T.

2000-12-01

In this paper, the results of an IEA-Workshop on Strategy and Planning of Fusion Materials Research and Development (R&D), held in October 1998 in Risø Denmark are summarised and further developed. Essential performance targets for materials to be used in first wall/breeding blanket components have been defined for the major materials groups under discussion: ferritic-martensitic steels, vanadium alloys and ceramic composites of the SiC/SiC-type. R&D strategies are proposed for their further development and qualification as reactor-relevant materials. The important role of existing irradiation facilities (mainly fission reactors) for materials testing within the next decade is described, and the limits for the transfer of results from such simulation experiments to fusion-relevant conditions are addressed. The importance of a fusion-relevant high-intensity neutron source for the development of structural as well as breeding and special purpose materials is elaborated and the reasons for the selection of an accelerator-driven D-Li-neutron source - the International Fusion Materials Irradiation Facility (IFMIF) - as an appropriate test bed are explained. Finally the necessity to execute the materials programme for fusion in close international collaboration, presently promoted by the International Energy Agency, IEA is emphasised.

Towards a programme of testing and qualification for structural and plasma-facing materials in ‘fusion neutron’ environments

NASA Astrophysics Data System (ADS)

Stork, D.; Heidinger, R.; Muroga, T.; Zinkle, S. J.; Moeslang, A.; Porton, M.; Boutard, J.-L.; Gonzalez, S.; Ibarra, A.

2017-09-01

Materials damage by 14.1MeV neutrons from deuterium-tritium (D-T) fusion reactions can only be characterised definitively by subjecting a relevant configuration of test materials to high-intensity ‘fusion-neutron spectrum sources’, i.e. those simulating closely D-T fusion-neutron spectra. This provides major challenges to programmes to design and construct a demonstration fusion reactor prior to having a large-scale, high-intensity source of such neutrons. In this paper, we discuss the different aspects related to these ‘relevant configuration’ tests, including: • generic issues in materials qualification/validation, comparing safety requirements against those of investment protection; • lessons learned from the fission programme, enabling a reduced fusion materials testing programme; • the use and limitations of presently available possible irradiation sources to optimise a fusion neutron testing program including fission-neutron irradiation of isotopically and chemically tailored steels, ion damage by high-energy helium ions and self-ion beams, or irradiation studies with neutron sources of non-fusion spectra; and • the different potential sources of simulated fusion neutron spectra and the choice using stripping reactions from deuterium-beam ions incident on light-element targets.

Numerical study of neutron beam divergence in a beam-fusion scenario employing laser driven ions

NASA Astrophysics Data System (ADS)

Alejo, A.; Green, A.; Ahmed, H.; Robinson, A. P. L.; Cerchez, M.; Clarke, R.; Doria, D.; Dorkings, S.; Fernandez, J.; McKenna, P.; Mirfayzi, S. R.; Naughton, K.; Neely, D.; Norreys, P.; Peth, C.; Powell, H.; Ruiz, J. A.; Swain, J.; Willi, O.; Borghesi, M.; Kar, S.

2016-09-01

The most established route to create a laser-based neutron source is by employing laser accelerated, low atomic-number ions in fusion reactions. In addition to the high reaction cross-sections at moderate energies of the projectile ions, the anisotropy in neutron emission is another important feature of beam-fusion reactions. Using a simple numerical model based on neutron generation in a pitcher-catcher scenario, anisotropy in neutron emission was studied for the deuterium-deuterium fusion reaction. Simulation results are consistent with the narrow-divergence (∼ 70 ° full width at half maximum) neutron beam recently served in an experiment employing multi-MeV deuteron beams of narrow divergence (up to 30° FWHM, depending on the ion energy) accelerated by a sub-petawatt laser pulse from thin deuterated plastic foils via the Target Normal Sheath Acceleration mechanism. By varying the input ion beam parameters, simulations show that a further improvement in the neutron beam directionality (i.e. reduction in the beam divergence) can be obtained by increasing the projectile ion beam temperature and cut-off energy, as expected from interactions employing higher power lasers at upcoming facilities.

Plasma Power Station with Quasi Spherical Direct Drive Capsule for Fusion Yield and Inverse Diode for Driver-Target Coupling

DOE PAGES

VanDevender, J. P.; Cuneo, M. E.; Slutz, S. A.; ...

2012-01-01

The Meier-Moir economic model for Pulsed Power Driven Inertial Fusion Energy shows at least two approaches for fusion energy at 7 to 8 cents/kw-hr: One with large yield at 0.1 Hz and presented by M. E. Cuneo at ICENES 2011 and one with smaller yield at 3 Hz presented in this paper. Both use very efficient and low cost Linear Transformer Drivers (LTDs) for the pulsed power. Here, we report the system configuration and end-to-end simulation for the latter option, which is called the Plasma Power Station (PPS), and report the first results on the two, least mature, enabling technologies:more » a magnetically driven Quasi Spherical Direct Drive (QSDD) capsule for the fusion yield and an Inverse Diode for coupling the driver to the target. In addition, we describe the issues and propose to address the issues with a prototype of the PPS on the Saturn accelerator and with experiments on a short pulse modification of the Z accelerator test the validity of simulations showing megajoule thermonuclear yield with DT on a modified Z.« less

Coupled diffusion in lipid bilayers upon close approach

DOE PAGES

Pronk, Sander; Lindahl, Erik; Kasson, Peter M.

2014-12-23

Biomembrane interfaces create regions of slowed water dynamics in their vicinity. When two lipid bilayers come together, this effect is further accentuated, and the associated slowdown can affect the dynamics of larger-scale processes such as membrane fusion. We have used molecular dynamics simulations to examine how lipid and water dynamics are affected as two lipid bilayers approach each other. These two interacting fluid systems, lipid and water, both slow and become coupled when the lipid membranes are separated by a thin water layer. We show in particular that the water dynamics become glassy, and diffusion of lipids in the apposedmore » leaflets becomes coupled across the water layer, while the “outer” leaflets remain unaffected. This dynamic coupling between bilayers appears mediated by lipid–water–lipid hydrogen bonding, as it occurs at bilayer separations where water–lipid hydrogen bonds become more common than water–water hydrogen bonds. We further show that such coupling occurs in simulations of vesicle–vesicle fusion prior to the fusion event itself. As a result, such altered dynamics at membrane–membrane interfaces may both stabilize the interfacial contact and slow fusion stalk formation within the interface region.« less

Relative Contributions of the Midcarpal and Radiocarpal Joints to Dart-Thrower's Motion at the Wrist.

PubMed

Kane, Patrick M; Vopat, Bryan G; Mansuripur, P Kaveh; Gaspar, Michael P; Wolfe, Scott W; Crisco, Joseph J; Got, Christopher

2018-03-01

To identify the relative contributions of the radiocarpal (RC) and midcarpal (MC) joints to dart-thrower's motion (DTM) of the wrist. Six cadaveric upper extremities were fixed to a custom-designed loading jig allowing for pure moment-rotation analysis in 24 different directions of wrist motion. Each specimen was tested in 3 states: intact, simulated radiocarpal fusion (sRCF) and simulated pancarpal fusion (sPCF). Moments of ± 1.5 Nm were applied at each of 24 directions for each state and the resulting wrist rotation recorded. Data from each specimen were reduced to compute the range of motion (ROM) envelopes and the orientation of the ROM for the 3 different states. The ROM was significantly decreased in the sRCF and sPCF groups compared with the intact group in the directions of the pure extension, radial extension, ulnar flexion, and ulnar deviation. No significant difference in ROM was detected between the sRCF and sPCF groups in any direction. The ROM envelopes for the intact, sRCF, and sPCF groups were all oriented obliquely to the axis of pure wrist flexion-extension near a path of ulnar flexion-radial extension, consistent with prior reports on DTM. Although both simulated fusion types decreased ROM compared with the intact wrist, the principal direction of wrist motion along the path of DTM was not significantly altered by simulated RCF or PCF. These findings suggest that the RC and MC joints can each contribute to a similar mechanical axis of motion located along the path of DTM when the other joint has been eliminated via fusion. Surgical options such as partial wrist fusions may maintain the native wrist's mechanical axis if either the RC or the MC joint is preserved, despite significant reduction in overall ROM. Copyright © 2018 American Society for Surgery of the Hand. Published by Elsevier Inc. All rights reserved.

Overview of theory and simulations in the Heavy Ion Fusion Science Virtual National Laboratory

NASA Astrophysics Data System (ADS)

Friedman, Alex

2007-07-01

The Heavy Ion Fusion Science Virtual National Laboratory (HIFS-VNL) is a collaboration of Lawrence Berkeley National Laboratory, Lawrence Livermore National Laboratory, and Princeton Plasma Physics Laboratory. These laboratories, in cooperation with researchers at other institutions, are carrying out a coordinated effort to apply intense ion beams as drivers for studies of the physics of matter at extreme conditions, and ultimately for inertial fusion energy. Progress on this endeavor depends upon coordinated application of experiments, theory, and simulations. This paper describes the state of the art, with an emphasis on the coordination of modeling and experiment; developments in the simulation tools, and in the methods that underly them, are also treated.

Angular radiation temperature simulation for time-dependent capsule drive prediction in inertial confinement fusion

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jing, Longfei; Yang, Dong; Li, Hang

2015-02-15

The x-ray drive on a capsule in an inertial confinement fusion setup is crucial for ignition. Unfortunately, a direct measurement has not been possible so far. We propose an angular radiation temperature simulation to predict the time-dependent drive on the capsule. A simple model, based on the view-factor method for the simulation of the radiation temperature, is presented and compared with the experimental data obtained using the OMEGA laser facility and the simulation results acquired with VISRAD code. We found a good agreement between the time-dependent measurements and the simulation results obtained using this model. The validated model was thenmore » used to analyze the experimental results from the Shenguang-III prototype laser facility. More specifically, the variations of the peak radiation temperatures at different view angles with the albedo of the hohlraum, the motion of the laser spots, the closure of the laser entrance holes, and the deviation of the laser power were investigated. Furthermore, the time-dependent radiation temperature at different orientations and the drive history on the capsule were calculated. The results indicate that the radiation temperature from “U20W112” (named according to the diagnostic hole ID on the target chamber) can be used to approximately predict the drive temperature on the capsule. In addition, the influence of the capsule on the peak radiation temperature is also presented.« less

A Thermo-Poromechanics Finite Element Model for Predicting Arterial Tissue Fusion

NASA Astrophysics Data System (ADS)

Fankell, Douglas P.

This work provides modeling efforts and supplemental experimental work performed towards the ultimate goal of modeling heat transfer, mass transfer, and deformation occurring in biological tissue, in particular during arterial fusion and cutting. Developing accurate models of these processes accomplishes two goals. First, accurate models would enable engineers to design devices to be safer and less expensive. Second, the mechanisms behind tissue fusion and cutting are widely unknown; models with the ability to accurately predict physical phenomena occurring in the tissue will allow for insight into the underlying mechanisms of the processes. This work presents three aims and the efforts in achieving them, leading to an accurate model of tissue fusion and more broadly the thermo-poromechanics (TPM) occurring within biological tissue. Chapters 1 and 2 provide the motivation for developing accurate TPM models of biological tissue and an overview of previous modeling efforts. In Chapter 3, a coupled thermo-structural finite element (FE) model with the ability to predict arterial cutting is offered. From the work presented in Chapter 3, it became obvious a more detailed model was needed. Chapter 4 meets this need by presenting small strain TPM theory and its implementation in an FE code. The model is then used to simulate thermal tissue fusion. These simulations show the model's promise in predicting the water content and temperature of arterial wall tissue during the fusion process, but it is limited by its small deformation assumptions. Chapters 5-7 attempt to address this limitation by developing and implementing a large deformation TPM FE model. Chapters 5, 6, and 7 present a thermodynamically consistent, large deformation TPM FE model and its ability to simulate tissue fusion. Ultimately, this work provides several methods of simulating arterial tissue fusion and the thermo-poromechanics of biological tissue. It is the first work, to the author's knowledge, to simulate the fully coupled TPM of biological tissue and the first to present a fully coupled large deformation TPM FE model. In doing so, a stepping stone for more advanced modeling of biological tissue has been laid.

A Simulation Environment for Benchmarking Sensor Fusion-Based Pose Estimators.

PubMed

Ligorio, Gabriele; Sabatini, Angelo Maria

2015-12-19

In-depth analysis and performance evaluation of sensor fusion-based estimators may be critical when performed using real-world sensor data. For this reason, simulation is widely recognized as one of the most powerful tools for algorithm benchmarking. In this paper, we present a simulation framework suitable for assessing the performance of sensor fusion-based pose estimators. The systems used for implementing the framework were magnetic/inertial measurement units (MIMUs) and a camera, although the addition of further sensing modalities is straightforward. Typical nuisance factors were also included for each sensor. The proposed simulation environment was validated using real-life sensor data employed for motion tracking. The higher mismatch between real and simulated sensors was about 5% of the measured quantity (for the camera simulation), whereas a lower correlation was found for an axis of the gyroscope (0.90). In addition, a real benchmarking example of an extended Kalman filter for pose estimation from MIMU and camera data is presented.

SU-D-304-07: Application of Proton Boron Fusion Reaction to Radiation Therapy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jung, J; Yoon, D; Shin, H

Purpose: we present the introduction of a therapy method using the proton boron fusion reaction. The purpose of this study is to verify the theoretical validity of proton boron fusion therapy using Monte Carlo simulations. Methods: After boron is accumulated in the tumor region, the emitted from outside the body proton can react with the boron in the tumor region. An increase of the proton’s maximum dose level is caused by the boron and only the tumor cell is damaged more critically. In addition, a prompt gamma ray is emitted from the proton boron reaction point. Here we show thatmore » the effectiveness of the proton boron fusion therapy (PBFT) was verified using Monte Carlo simulations. Results: We found that a dramatic increase by more than half of the proton’s maximum dose level was induced by the boron in the tumor region. This increase occurred only when the proton’s maximum dose point was located within the boron uptake region (BUR). In addition, the 719 keV prompt gamma ray peak produced by the proton boron fusion reaction was positively detected. Conclusion: This therapy method features the advantages such as the application of Bragg-peak to the therapy, the accurate targeting of tumor, improved therapy effects, and the monitoring of the therapy region during treatment.« less

Data fusion of multi-scale representations for structural damage detection

NASA Astrophysics Data System (ADS)

Guo, Tian; Xu, Zili

2018-01-01

Despite extensive researches into structural health monitoring (SHM) in the past decades, there are few methods that can detect multiple slight damage in noisy environments. Here, we introduce a new hybrid method that utilizes multi-scale space theory and data fusion approach for multiple damage detection in beams and plates. A cascade filtering approach provides multi-scale space for noisy mode shapes and filters the fluctuations caused by measurement noise. In multi-scale space, a series of amplification and data fusion algorithms are utilized to search the damage features across all possible scales. We verify the effectiveness of the method by numerical simulation using damaged beams and plates with various types of boundary conditions. Monte Carlo simulations are conducted to illustrate the effectiveness and noise immunity of the proposed method. The applicability is further validated via laboratory cases studies focusing on different damage scenarios. Both results demonstrate that the proposed method has a superior noise tolerant ability, as well as damage sensitivity, without knowing material properties or boundary conditions.

Research on the strategy of underwater united detection fusion and communication using multi-sensor

NASA Astrophysics Data System (ADS)

Xu, Zhenhua; Huang, Jianguo; Huang, Hai; Zhang, Qunfei

2011-09-01

In order to solve the distributed detection fusion problem of underwater target detection, when the signal to noise ratio (SNR) of the acoustic channel is low, a new strategy for united detection fusion and communication using multiple sensors was proposed. The performance of detection fusion was studied and compared based on the Neyman-Pearson principle when the binary phase shift keying (BPSK) and on-off keying (OOK) modes were used by the local sensors. The comparative simulation and analysis between the optimal likelihood ratio test and the proposed strategy was completed, and both the theoretical analysis and simulation indicate that using the proposed new strategy could improve the detection performance effectively. In theory, the proposed strategy of united detection fusion and communication is of great significance to the establishment of an underwater target detection system.

Hybrid testing of lumbar CHARITE discs versus fusions.

PubMed

Panjabi, Manohar; Malcolmson, George; Teng, Edward; Tominaga, Yasuhiro; Henderson, Gweneth; Serhan, Hassan

2007-04-20

An in vitro human cadaveric biomechanical study. To quantify effects on operated and other levels, including adjacent levels, due to CHARITE disc implantations versus simulated fusions, using follower load and the new hybrid test method in flexion-extension and bilateral torsion. Spinal fusion has been associated with long-term accelerated degeneration at adjacent levels. As opposed to the fusion, artificial discs are designed to preserve motion and diminish the adjacent-level effects. Five fresh human cadaveric lumbar specimens (T12-S1) underwent multidirectional testing in flexion-extension and bilateral torsion with 400 N follower load. Intact specimen total ranges of motion were determined with +/-10 Nm unconstrained pure moments. The intact range of motion was used as input for the hybrid tests of 5 constructs: 1) CHARITE disc at L5-S1; 2) fusion at L5-S1; 3) CHARITE discs at L4-L5 and L5-S1; 4) CHARITE disc at L4-L5 and fusion at L5-S1; and 5) 2-level fusion at L4-L5-S1. Using repeated-measures single factor analysis of variance and Bonferroni statistical tests (P < 0.05), intervertebral motion redistribution of each construct was compared with the intact. In flexion-extension, 1-level CHARITE disc preserved motion at the operated and other levels, while 2-level CHARITE showed some amount of other-level effects. In contrast, 1- and 2-level fusions increased other-level motions (average, 21.0% and 61.9%, respectively). In torsion, both 1- and 2-level discs preserved motions at all levels. The 2-level simulated fusion increased motions at proximal levels (22.9%), while the 1-level fusion produced no significant changes. In general, CHARITE discs preserved operated- and other-level motions. Fusion simulations affected motion redistribution at other levels, including adjacent levels.

Coarse-Grain Simulations Reveal Movement of the Synaptobrevin C-Terminus in Response to Piconewton Forces

PubMed Central

Lindau, Manfred; Hall, Benjamin A.; Chetwynd, Alan; Beckstein, Oliver; Sansom, Mark S.P.

2012-01-01

Fusion of neurosecretory vesicles with the plasma membrane is mediated by SNARE proteins, which transfer a force to the membranes. However, the mechanism by which this force transfer induces fusion pore formation is still unknown. The neuronal vesicular SNARE protein synaptobrevin 2 (syb2) is anchored in the vesicle membrane by a single C-terminal transmembrane (TM) helix. In coarse-grain molecular-dynamics simulations, self-assembly of the membrane occurred with the syb2 TM domain inserted, as expected from experimental data. The free-energy profile for the position of the syb2 membrane anchor in the membrane was determined using umbrella sampling. To predict the free-energy landscapes for a reaction pathway pulling syb2 toward the extravesicular side of the membrane, which is the direction of the force transfer from the SNARE complex, harmonic potentials were applied to the peptide in its unbiased position, pulling it toward new biased equilibrium positions. Application of piconewton forces to the extravesicular end of the TM helix in the simulation detached the synaptobrevin C-terminus from the vesicle's inner-leaflet lipid headgroups and pulled it deeper into the membrane. This C-terminal movement was facilitated and hindered by specific mutations in parallel with experimentally observed facilitation and inhibition of fusion. Direct application of such forces to the intravesicular end of the TM domain resulted in tilting motion of the TM domain through the membrane with an activation energy of ∼70 kJ/mol. The results suggest a mechanism whereby fusion pore formation is induced by movement of the charged syb2 C-terminus within the membrane in response to pulling and tilting forces generated by C-terminal zippering of the SNARE complex. PMID:23009845

Coarse-grain simulations reveal movement of the synaptobrevin C-terminus in response to piconewton forces.

PubMed

Lindau, Manfred; Hall, Benjamin A; Chetwynd, Alan; Beckstein, Oliver; Sansom, Mark S P

2012-09-05

Fusion of neurosecretory vesicles with the plasma membrane is mediated by SNARE proteins, which transfer a force to the membranes. However, the mechanism by which this force transfer induces fusion pore formation is still unknown. The neuronal vesicular SNARE protein synaptobrevin 2 (syb2) is anchored in the vesicle membrane by a single C-terminal transmembrane (TM) helix. In coarse-grain molecular-dynamics simulations, self-assembly of the membrane occurred with the syb2 TM domain inserted, as expected from experimental data. The free-energy profile for the position of the syb2 membrane anchor in the membrane was determined using umbrella sampling. To predict the free-energy landscapes for a reaction pathway pulling syb2 toward the extravesicular side of the membrane, which is the direction of the force transfer from the SNARE complex, harmonic potentials were applied to the peptide in its unbiased position, pulling it toward new biased equilibrium positions. Application of piconewton forces to the extravesicular end of the TM helix in the simulation detached the synaptobrevin C-terminus from the vesicle's inner-leaflet lipid headgroups and pulled it deeper into the membrane. This C-terminal movement was facilitated and hindered by specific mutations in parallel with experimentally observed facilitation and inhibition of fusion. Direct application of such forces to the intravesicular end of the TM domain resulted in tilting motion of the TM domain through the membrane with an activation energy of ∼70 kJ/mol. The results suggest a mechanism whereby fusion pore formation is induced by movement of the charged syb2 C-terminus within the membrane in response to pulling and tilting forces generated by C-terminal zippering of the SNARE complex. Copyright © 2012 Biophysical Society. Published by Elsevier Inc. All rights reserved.

Fusion of GEDI, ICESAT2 & NISAR data for above ground biomass mapping in Sonoma County, California

NASA Astrophysics Data System (ADS)

Duncanson, L.; Simard, M.; Thomas, N. M.; Neuenschwander, A. L.; Hancock, S.; Armston, J.; Dubayah, R.; Hofton, M. A.; Huang, W.; Tang, H.; Marselis, S.; Fatoyinbo, T.

2017-12-01

Several upcoming NASA missions will collect data sensitive to forest structure (GEDI, ICESAT-2 & NISAR). The LiDAR and SAR data collected by these missions will be used in coming years to map forest aboveground biomass at various resolutions. This research focuses on developing and testing multi-sensor data fusion approaches in advance of these missions. Here, we present the first case study of a CMS-16 grant with results from Sonoma County, California. We simulate lidar and SAR datasets from GEDI, ICESAT-2 and NISAR using airborne discrete return lidar and UAVSAR data, respectively. GEDI and ICESAT-2 signals are simulated from high point density discrete return lidar that was acquired over the entire county in 2014 through a previous CMS project (Dubayah & Hurtt, CMS-13). NISAR is simulated from L-band UAVSAR data collected in 2014. These simulations are empirically related to 300 field plots of aboveground biomass as well as a 30m biomass map produced from the 2014 airborne lidar data. We model biomass independently for each simulated mission dataset and then test two fusion methods for County-wide mapping 1) a pixel based approach and 2) an object oriented approach. In the pixel-based approach, GEDI and ICESAT-2 biomass models are calibrated over field plots and applied in orbital simulations for a 2-year period of the GEDI and ICESAT-2 missions. These simulated samples are then used to calibrate UAVSAR data to produce a 0.25 ha map. In the object oriented approach, the GEDI and ICESAT-2 data are identical to the pixel-based approach, but calibrate image objects of similar L-band backscatter rather than uniform pixels. The results of this research demonstrate the estimated ability for each of these three missions to independently map biomass in a temperate, high biomass system, as well as the potential improvement expected through combining mission datasets.

An optimized data fusion method and its application to improve lateral boundary conditions in winter for Pearl River Delta regional PM2.5 modeling, China

NASA Astrophysics Data System (ADS)

Huang, Zhijiong; Hu, Yongtao; Zheng, Junyu; Zhai, Xinxin; Huang, Ran

2018-05-01

Lateral boundary conditions (LBCs) are essential for chemical transport models to simulate regional transport; however they often contain large uncertainties. This study proposes an optimized data fusion approach to reduce the bias of LBCs by fusing gridded model outputs, from which the daughter domain's LBCs are derived, with ground-level measurements. The optimized data fusion approach follows the framework of a previous interpolation-based fusion method but improves it by using a bias kriging method to correct the spatial bias in gridded model outputs. Cross-validation shows that the optimized approach better estimates fused fields in areas with a large number of observations compared to the previous interpolation-based method. The optimized approach was applied to correct LBCs of PM2.5 concentrations for simulations in the Pearl River Delta (PRD) region as a case study. Evaluations show that the LBCs corrected by data fusion improve in-domain PM2.5 simulations in terms of the magnitude and temporal variance. Correlation increases by 0.13-0.18 and fractional bias (FB) decreases by approximately 3%-15%. This study demonstrates the feasibility of applying data fusion to improve regional air quality modeling.

Two-Plasmon Decay: Simulations and Experiments on the NIKE Laser System

NASA Astrophysics Data System (ADS)

Phillips, Lee; Weaver, J. L.; Oh, J.; Schmitt, A. J.; Obenschain, S.; Colombant, D.

2009-11-01

NIKE is a Krf laser system at the Naval Research Laboratory used to explore hydrodynamic stability, equation of state, and other issues arising in the research toward inertial fusion energy. The relatively small KrF wavelength, according to widely used theories, raises the threshold of most parametric instabilities. We report on simulations performed using the FAST3d radiation hydrocode to design TPD experiments. By post-processing the results of the simulations we have designed experiments that have explored the use of simple threshold formulas (from developing theories) and help establish the soundness of our simulational approach. Turning to the targets proposed for ICF energy research, we have found that among the designs for the proposed Fusion Test Facility (Obenschain et al., Phys. Plasmas 13 056320 (2006)), are some that are below LPI thresholds. We have also studied high-gain KrF shock ignition designs and found that they are below LPI thresholds for most of the implosion, becoming susceptible to TPD only late in the pulse.

Static load simulation of steering knuckle for a formula student race car

NASA Astrophysics Data System (ADS)

Saputro, Bagus Aulia; Ubaidillah, Triono, Dicky Agus; Pratama, Dzaky Roja; Cahyono, Sukmaji Indro; Imaduddin, Fitrian

2018-02-01

This research aims to determine the stress distribution which occurs on the steering knuckle and to define its safety factor number. Steering knuckle is the most critical part of a car's steering system. Steering knuckle supports the tie rod, brake caliper, and the wheels to provide stability. Steering knuckle withstands the load which given on the front wheels and functions as the wheel's axis. Balljoint and king support the rotation of the suspension arm. When the car is in idle position, knuckle hold the weight of the car, it gets braking force when it's braking and cornering. Knuckle is designed to have the strength that could withstand load and to have a good safety factor value. Knuckle is designed using Fusion software then simulated using Fusion simulation software with a static load, moment braking force, and cornering force as the loads in this simulation. The simulation works in ideal condition. The result of this simulation is satisfying. This simulation produces a maximum displacement of 0.01281mm, the maximum shear stress is 3.707 MPa on the stub hole, and the safety factor is 5.24. The material used for this product is mild steel AISI 1018.

Runtime Simulation for Post-Disaster Data Fusion Visualization

DTIC Science & Technology

2006-10-01

Center for Multisource Information Fusion ( CMIF ) The State University of New York at Buffalo Buffalo, NY 14260 USA kesh@eng.buffalo.edu ABSTRACT...Fusion ( CMIF ) The State University of New York at Buffalo Buffalo, NY 14260 USA 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING

Development of heat sink concept for near-term fusion power plant divertor

NASA Astrophysics Data System (ADS)

Rimza, Sandeep; Khirwadkar, Samir; Velusamy, Karupanna

2017-04-01

Development of an efficient divertor concept is an important task to meet in the scenario of the future fusion power plant. The divertor, which is a vital part of the reactor has to discharge the considerable fraction of the total fusion thermal power (∼15%). Therefore, it has to survive very high thermal fluxes (∼10 MW/m2). In the present paper, an efficient divertor heat exchanger cooled by helium is proposed for the fusion tokamak. The Plasma facing surface of divertor made-up of several modules to overcome the stresses caused by high heat flux. The thermal hydraulic performance of one such module is numerically investigated in the present work. The result shows that the proposed design is capable of handling target heat flux values of 10 MW/m2. The computational model has been validated against high-heat flux experiments and a satisfactory agreement is noticed between the present simulation and the reported results.

Multiview fusion for activity recognition using deep neural networks

NASA Astrophysics Data System (ADS)

Kavi, Rahul; Kulathumani, Vinod; Rohit, Fnu; Kecojevic, Vlad

2016-07-01

Convolutional neural networks (ConvNets) coupled with long short term memory (LSTM) networks have been recently shown to be effective for video classification as they combine the automatic feature extraction capabilities of a neural network with additional memory in the temporal domain. This paper shows how multiview fusion can be applied to such a ConvNet LSTM architecture. Two different fusion techniques are presented. The system is first evaluated in the context of a driver activity recognition system using data collected in a multicamera driving simulator. These results show significant improvement in accuracy with multiview fusion and also show that deep learning performs better than a traditional approach using spatiotemporal features even without requiring any background subtraction. The system is also validated on another publicly available multiview action recognition dataset that has 12 action classes and 8 camera views.

Information fusion based optimal control for large civil aircraft system.

PubMed

Zhen, Ziyang; Jiang, Ju; Wang, Xinhua; Gao, Chen

2015-03-01

Wind disturbance has a great influence on landing security of Large Civil Aircraft. Through simulation research and engineering experience, it can be found that PID control is not good enough to solve the problem of restraining the wind disturbance. This paper focuses on anti-wind attitude control for Large Civil Aircraft in landing phase. In order to improve the riding comfort and the flight security, an information fusion based optimal control strategy is presented to restrain the wind in landing phase for maintaining attitudes and airspeed. Data of Boeing707 is used to establish a nonlinear mode with total variables of Large Civil Aircraft, and then two linear models are obtained which are divided into longitudinal and lateral equations. Based on engineering experience, the longitudinal channel adopts PID control and C inner control to keep longitudinal attitude constant, and applies autothrottle system for keeping airspeed constant, while an information fusion based optimal regulator in the lateral control channel is designed to achieve lateral attitude holding. According to information fusion estimation, by fusing hard constraint information of system dynamic equations and the soft constraint information of performance index function, optimal estimation of the control sequence is derived. Based on this, an information fusion state regulator is deduced for discrete time linear system with disturbance. The simulation results of nonlinear model of aircraft indicate that the information fusion optimal control is better than traditional PID control, LQR control and LQR control with integral action, in anti-wind disturbance performance in the landing phase. Copyright © 2014 ISA. Published by Elsevier Ltd. All rights reserved.

Recurrent PAX3-MAML3 Fusion in Biphenotypic Sinonasal Sarcoma

PubMed Central

Wang, Xiaoke; Bledsoe, Krista L.; Graham, Rondell P.; Asmann, Yan W.; Viswanatha, David S.; Lewis, Jean E.; Lewis, Jason T.; Chou, Margaret M.; Yaszemski, Michael J.; Jen, Jin; Westendorf, Jennifer J.; Oliveira, André M.

2014-01-01

Biphenotypic sinonasal sarcoma (SNS) is a newly described tumor of the nasal and paranasal areas. Herein, we report the novel recurring chromosomal translocation t(2;4)(q35;q31.1) in SNS. The translocation results in the formation of the fusion protein PAX3-MAML3, which is a potent transcriptional activator of PAX3 response elements. The SNS phenotype is characterized by aberrant expression of genes involved in neuroectodermal and myogenic differentiation, which closely simulates the developmental roles of PAX3. PMID:24859338

Modeling the Compression of Merged Compact Toroids by Multiple Plasma Jets

NASA Technical Reports Server (NTRS)

Thio, Y. C. Francis; Knapp, Charles E.; Kirkpatrick, Ron; Rodgers, Stephen L. (Technical Monitor)

2000-01-01

A fusion propulsion scheme has been proposed that makes use of the merging of a spherical distribution of plasma jets to dynamically form a gaseous liner. The gaseous liner is used to implode a magnetized target to produce the fusion reaction in a standoff manner. In this paper, the merging of the plasma jets to form the gaseous liner is investigated numerically. The Los Alamos SPHINX code, based on the smoothed particle hydrodynamics method is used to model the interaction of the jets. 2-D and 3-D simulations have been performed to study the characteristics of the resulting flow when these jets collide. The results show that the jets merge to form a plasma liner that converge radially which may be used to compress the central plasma to fusion conditions. Details of the computational model and the SPH numerical methods will be presented together with the numerical results.

Benefits of Moderate-Z Ablators for Direct-Drive Inertial Confinement Fusion

NASA Astrophysics Data System (ADS)

Lafon, M.; Betti, R.; Anderson, K. S.; Collins, T. J. B.; Skupsky, S.; McKenty, P. W.

2014-10-01

Control of hydrodynamic instabilities and DT-fuel preheating by hot electrons produced by laser-plasma interaction is crucial in inertial confinement fusion. Moderate- Z ablators have been shown to reduce the laser imprinting on target and suppress the generation of hot electrons from the two-plasmon-decay instability. These results have motivated the use of ablators of higher- Z than pure plastic in direct-drive-ignition target designs for the National Ignition Facility (NIF). Two-dimensional radiation-hydrodynamic simulations assess the robustness of these ignition designs to laser imprint and capsule nonuniformities. The complex behavior of the hydrodynamic stability of mid- Z ablators is investigated through single and multimode simulations. A polar-drive configuration is developed within the NIF Laser System specifications for each ablator material. The use of multilayer ablators is also investigated to enhance the hydrodynamic stability. Results indicate that ignition target designs using mid- Z ablators exhibit good hydrodynamic properties, leading to high target gain for direct-drive implosions on the NIF. This material is based upon work supported by the Department of Energy National Nuclear Security Administration under Award Number DE-NA0001944 and the Office of Fusion Energy Sciences Number DE-FG02-04ER54786.

Comparison between initial Magnetized Liner Inertial Fusion experiments and integrated simulations

NASA Astrophysics Data System (ADS)

Sefkow, A. B.; Gomez, M. R.; Geissel, M.; Hahn, K. D.; Hansen, S. B.; Harding, E. C.; Peterson, K. J.; Slutz, S. A.; Koning, J. M.; Marinak, M. M.

2014-10-01

The Magnetized Liner Inertial Fusion (MagLIF) approach to ICF has obtained thermonuclear fusion yields using the Z facility. Integrated magnetohydrodynamic simulations provided the design for the first neutron-producing experiments using capabilities that presently exist, and the initial experiments measured stagnation radii rstag < 75 μm, temperatures around 3 keV, and isotropic neutron yields up to YnDD = 2 ×1012 from imploded liners reaching peak velocities around 70 km/s over an implosion time of about 60 ns. We present comparisons between the experimental observables and post-shot degraded integrated simulations. Sandia is a multiprogram laboratory operated by Sandia Corporation, a Lockheed Martin Company, for the National Nuclear Security Administration under Contract DE-AC04-94AL85000.

Detailed high-resolution three-dimensional simulations of OMEGA separated reactants inertial confinement fusion experiments

DOE PAGES

Haines, Brian Michael; Grim, Gary P.; Fincke, James R.; ...

2016-07-29

Here, we present results from the comparison of high-resolution three-dimensional (3D) simulations with data from the implosions of inertial confinement fusion capsules with separated reactants performed on the OMEGA laser facility. Each capsule, referred to as a “CD Mixcap,” is filled with tritium and has a polystyrene (CH) shell with a deuterated polystyrene (CD) layer whose burial depth is varied. In these implosions, fusion reactions between deuterium and tritium ions can occur only in the presence of atomic mix between the gas fill and shell material. The simulations feature accurate models for all known experimental asymmetries and do not employmore » any adjustable parameters to improve agreement with experimental data. Simulations are performed with the RAGE radiation-hydrodynamics code using an Implicit Large Eddy Simulation (ILES) strategy for the hydrodynamics. We obtain good agreement with the experimental data, including the DT/TT neutron yield ratios used to diagnose mix, for all burial depths of the deuterated shell layer. Additionally, simulations demonstrate good agreement with converged simulations employing explicit models for plasma diffusion and viscosity, suggesting that the implicit sub-grid model used in ILES is sufficient to model these processes in these experiments. In our simulations, mixing is driven by short-wavelength asymmetries and longer-wavelength features are responsible for developing flows that transport mixed material towards the center of the hot spot. Mix material transported by this process is responsible for most of the mix (DT) yield even for the capsule with a CD layer adjacent to the tritium fuel. Consistent with our previous results, mix does not play a significant role in TT neutron yield degradation; instead, this is dominated by the displacement of fuel from the center of the implosion due to the development of turbulent instabilities seeded by long-wavelength asymmetries. Through these processes, the long-wavelength asymmetries degrade TT yield more than the DT yield and thus bring DT/TT neutron yield ratios into agreement with experiment. Finally, we present a detailed comparison of the flows in 2D and 3D simulations.« less

Detailed high-resolution three-dimensional simulations of OMEGA separated reactants inertial confinement fusion experiments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Haines, Brian M., E-mail: bmhaines@lanl.gov; Fincke, James R.; Shah, Rahul C.

We present results from the comparison of high-resolution three-dimensional (3D) simulations with data from the implosions of inertial confinement fusion capsules with separated reactants performed on the OMEGA laser facility. Each capsule, referred to as a “CD Mixcap,” is filled with tritium and has a polystyrene (CH) shell with a deuterated polystyrene (CD) layer whose burial depth is varied. In these implosions, fusion reactions between deuterium and tritium ions can occur only in the presence of atomic mix between the gas fill and shell material. The simulations feature accurate models for all known experimental asymmetries and do not employ anymore » adjustable parameters to improve agreement with experimental data. Simulations are performed with the RAGE radiation-hydrodynamics code using an Implicit Large Eddy Simulation (ILES) strategy for the hydrodynamics. We obtain good agreement with the experimental data, including the DT/TT neutron yield ratios used to diagnose mix, for all burial depths of the deuterated shell layer. Additionally, simulations demonstrate good agreement with converged simulations employing explicit models for plasma diffusion and viscosity, suggesting that the implicit sub-grid model used in ILES is sufficient to model these processes in these experiments. In our simulations, mixing is driven by short-wavelength asymmetries and longer-wavelength features are responsible for developing flows that transport mixed material towards the center of the hot spot. Mix material transported by this process is responsible for most of the mix (DT) yield even for the capsule with a CD layer adjacent to the tritium fuel. Consistent with our previous results, mix does not play a significant role in TT neutron yield degradation; instead, this is dominated by the displacement of fuel from the center of the implosion due to the development of turbulent instabilities seeded by long-wavelength asymmetries. Through these processes, the long-wavelength asymmetries degrade TT yield more than the DT yield and thus bring DT/TT neutron yield ratios into agreement with experiment. Finally, we present a detailed comparison of the flows in 2D and 3D simulations.« less

Detailed high-resolution three-dimensional simulations of OMEGA separated reactants inertial confinement fusion experiments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Haines, Brian Michael; Grim, Gary P.; Fincke, James R.

Here, we present results from the comparison of high-resolution three-dimensional (3D) simulations with data from the implosions of inertial confinement fusion capsules with separated reactants performed on the OMEGA laser facility. Each capsule, referred to as a “CD Mixcap,” is filled with tritium and has a polystyrene (CH) shell with a deuterated polystyrene (CD) layer whose burial depth is varied. In these implosions, fusion reactions between deuterium and tritium ions can occur only in the presence of atomic mix between the gas fill and shell material. The simulations feature accurate models for all known experimental asymmetries and do not employmore » any adjustable parameters to improve agreement with experimental data. Simulations are performed with the RAGE radiation-hydrodynamics code using an Implicit Large Eddy Simulation (ILES) strategy for the hydrodynamics. We obtain good agreement with the experimental data, including the DT/TT neutron yield ratios used to diagnose mix, for all burial depths of the deuterated shell layer. Additionally, simulations demonstrate good agreement with converged simulations employing explicit models for plasma diffusion and viscosity, suggesting that the implicit sub-grid model used in ILES is sufficient to model these processes in these experiments. In our simulations, mixing is driven by short-wavelength asymmetries and longer-wavelength features are responsible for developing flows that transport mixed material towards the center of the hot spot. Mix material transported by this process is responsible for most of the mix (DT) yield even for the capsule with a CD layer adjacent to the tritium fuel. Consistent with our previous results, mix does not play a significant role in TT neutron yield degradation; instead, this is dominated by the displacement of fuel from the center of the implosion due to the development of turbulent instabilities seeded by long-wavelength asymmetries. Through these processes, the long-wavelength asymmetries degrade TT yield more than the DT yield and thus bring DT/TT neutron yield ratios into agreement with experiment. Finally, we present a detailed comparison of the flows in 2D and 3D simulations.« less

Detailed high-resolution three-dimensional simulations of OMEGA separated reactants inertial confinement fusion experiments

NASA Astrophysics Data System (ADS)

Haines, Brian M.; Grim, Gary P.; Fincke, James R.; Shah, Rahul C.; Forrest, Chad J.; Silverstein, Kevin; Marshall, Frederic J.; Boswell, Melissa; Fowler, Malcolm M.; Gore, Robert A.; Hayes-Sterbenz, Anna C.; Jungman, Gerard; Klein, Andreas; Rundberg, Robert S.; Steinkamp, Michael J.; Wilhelmy, Jerry B.

2016-07-01

We present results from the comparison of high-resolution three-dimensional (3D) simulations with data from the implosions of inertial confinement fusion capsules with separated reactants performed on the OMEGA laser facility. Each capsule, referred to as a "CD Mixcap," is filled with tritium and has a polystyrene (CH) shell with a deuterated polystyrene (CD) layer whose burial depth is varied. In these implosions, fusion reactions between deuterium and tritium ions can occur only in the presence of atomic mix between the gas fill and shell material. The simulations feature accurate models for all known experimental asymmetries and do not employ any adjustable parameters to improve agreement with experimental data. Simulations are performed with the RAGE radiation-hydrodynamics code using an Implicit Large Eddy Simulation (ILES) strategy for the hydrodynamics. We obtain good agreement with the experimental data, including the DT/TT neutron yield ratios used to diagnose mix, for all burial depths of the deuterated shell layer. Additionally, simulations demonstrate good agreement with converged simulations employing explicit models for plasma diffusion and viscosity, suggesting that the implicit sub-grid model used in ILES is sufficient to model these processes in these experiments. In our simulations, mixing is driven by short-wavelength asymmetries and longer-wavelength features are responsible for developing flows that transport mixed material towards the center of the hot spot. Mix material transported by this process is responsible for most of the mix (DT) yield even for the capsule with a CD layer adjacent to the tritium fuel. Consistent with our previous results, mix does not play a significant role in TT neutron yield degradation; instead, this is dominated by the displacement of fuel from the center of the implosion due to the development of turbulent instabilities seeded by long-wavelength asymmetries. Through these processes, the long-wavelength asymmetries degrade TT yield more than the DT yield and thus bring DT/TT neutron yield ratios into agreement with experiment. Finally, we present a detailed comparison of the flows in 2D and 3D simulations.

Dynamics simulations for engineering macromolecular interactions

PubMed Central

Robinson-Mosher, Avi; Shinar, Tamar; Silver, Pamela A.; Way, Jeffrey

2013-01-01

The predictable engineering of well-behaved transcriptional circuits is a central goal of synthetic biology. The artificial attachment of promoters to transcription factor genes usually results in noisy or chaotic behaviors, and such systems are unlikely to be useful in practical applications. Natural transcriptional regulation relies extensively on protein-protein interactions to insure tightly controlled behavior, but such tight control has been elusive in engineered systems. To help engineer protein-protein interactions, we have developed a molecular dynamics simulation framework that simplifies features of proteins moving by constrained Brownian motion, with the goal of performing long simulations. The behavior of a simulated protein system is determined by summation of forces that include a Brownian force, a drag force, excluded volume constraints, relative position constraints, and binding constraints that relate to experimentally determined on-rates and off-rates for chosen protein elements in a system. Proteins are abstracted as spheres. Binding surfaces are defined radially within a protein. Peptide linkers are abstracted as small protein-like spheres with rigid connections. To address whether our framework could generate useful predictions, we simulated the behavior of an engineered fusion protein consisting of two 20 000 Da proteins attached by flexible glycine/serine-type linkers. The two protein elements remained closely associated, as if constrained by a random walk in three dimensions of the peptide linker, as opposed to showing a distribution of distances expected if movement were dominated by Brownian motion of the protein domains only. We also simulated the behavior of fluorescent proteins tethered by a linker of varying length, compared the predicted Förster resonance energy transfer with previous experimental observations, and obtained a good correspondence. Finally, we simulated the binding behavior of a fusion of two ligands that could simultaneously bind to distinct cell-surface receptors, and explored the landscape of linker lengths and stiffnesses that could enhance receptor binding of one ligand when the other ligand has already bound to its receptor, thus, addressing potential mechanisms for improving targeted signal transduction proteins. These specific results have implications for the design of targeted fusion proteins and artificial transcription factors involving fusion of natural domains. More broadly, the simulation framework described here could be extended to include more detailed system features such as non-spherical protein shapes and electrostatics, without requiring detailed, computationally expensive specifications. This framework should be useful in predicting behavior of engineered protein systems including binding and dissociation reactions. PMID:23822508

Entropy-functional-based online adaptive decision fusion framework with application to wildfire detection in video.

PubMed

Gunay, Osman; Toreyin, Behçet Ugur; Kose, Kivanc; Cetin, A Enis

2012-05-01

In this paper, an entropy-functional-based online adaptive decision fusion (EADF) framework is developed for image analysis and computer vision applications. In this framework, it is assumed that the compound algorithm consists of several subalgorithms, each of which yields its own decision as a real number centered around zero, representing the confidence level of that particular subalgorithm. Decision values are linearly combined with weights that are updated online according to an active fusion method based on performing entropic projections onto convex sets describing subalgorithms. It is assumed that there is an oracle, who is usually a human operator, providing feedback to the decision fusion method. A video-based wildfire detection system was developed to evaluate the performance of the decision fusion algorithm. In this case, image data arrive sequentially, and the oracle is the security guard of the forest lookout tower, verifying the decision of the combined algorithm. The simulation results are presented.

A review of helium-hydrogen synergistic effects in radiation damage observed in fusion energy steels and an interaction model to guide future understanding

NASA Astrophysics Data System (ADS)

Marian, Jaime; Hoang, Tuan; Fluss, Michael; Hsiung, Luke L.

2015-07-01

Under fusion reactor conditions, large quantities of irradiation defects and transmutation gases are produced per unit time by neutrons, resulting in accelerated degradation of structural candidate ferritic (F) and ferritic/martensitic (F/M) steels. Due to the lack of a suitable fusion neutron testing facility, we must rely on high-dose-rate ion-beam experiments and present-day crude modeling estimates. Of particular interest is the possibility of synergistic (positive feedback) effects on materials properties due to the simultaneous action of He, H, and displacement damage (dpa) during operation. In this paper we discuss the state-of-the-art in terms of the experimental understanding of synergistic effects and carry out simulations of triple-species irradiation under ion-beam conditions using first-of-its-kind modeling techniques. Although, state-of-the-art modeling and simulation is not sufficiently well developed to shed light on the experimental uncertainties, we are able to conclude that it is not clear whether synergistic effects, the evidence of which is still not conclusive, will ultimately play a critical role in material performance under fusion energy conditions. We review here some of the evidence for the synergistic effects of hydrogen in the presence of helium and displacement damage, and also include some recent data from our research. While the experimental results to date suggest possible mechanisms for the observed synergistic effects, it is only with more advanced modeling that we can hope to understand the details underlying the experimental observations. By employing modeling and simulation we propose an interaction model that is qualitatively consistent with experimental observations of dpa/He/H irradiation behavior. Our modeling, the results of which should be helpful to researchers going forward, points to gaps and voids in the current understanding of triple ion-beam irradiation effects (displacement damage produced simultaneously with helium and hydrogen implantation) and the synergistic effects of hydrogen.

A review of helium–hydrogen synergistic effects in radiation damage observed in fusion energy steels and an interaction model to guide future understanding

DOE PAGES

Marian, Jaime; Hoang, Tuan; Fluss, Michael; ...

2014-12-29

Here, under fusion reactor conditions, large quantities of irradiation defects and transmutation gases are produced per unit time by neutrons, resulting in accelerated degradation of structural candidate ferritic (F) and ferritic/martensitic (F/M) steels. Due to the lack of a suitable fusion neutron testing facility, we must rely on high-dose-rate ion-beam experiments and present-day crude modeling estimates. Of particular interest is the possibility of synergistic (positive feedback) effects on materials properties due to the simultaneous action of He, H, and displacement damage (dpa) during operation. In this paper we discuss the state-of-the-art in terms of the experimental understanding of synergistic effectsmore » and carry out simulations of triple-species irradiation under ion-beam conditions using first-of-its-kind modeling techniques. Although, state-of-the-art modeling and simulation is not sufficiently well developed to shed light on the experimental uncertainties, we are able to conclude that it is not clear whether synergistic effects, the evidence of which is still not conclusive, will ultimately play a critical role in material performance under fusion energy conditions. We review here some of the evidence for the synergistic effects of hydrogen in the presence of helium and displacement damage, and also include some recent data from our research. While the experimental results to date suggest possible mechanisms for the observed synergistic effects, it is only with more advanced modeling that we can hope to understand the details underlying the experimental observations. By employing modeling and simulation we propose an interaction model that is qualitatively consistent with experimental observations of dpa/He/H irradiation behavior. Our modeling, the results of which should be helpful to researchers going forward, points to gaps and voids in the current understanding of triple ion-beam irradiation effects (displacement damage produced simultaneously with helium and hydrogen implantation) and the synergistic effects of hydrogen.« less

ITER Simulations Using the PEDESTAL Module in the PTRANSP Code

NASA Astrophysics Data System (ADS)

Halpern, F. D.; Bateman, G.; Kritz, A. H.; Pankin, A. Y.; Budny, R. V.; Kessel, C.; McCune, D.; Onjun, T.

2006-10-01

PTRANSP simulations with a computed pedestal height are carried out for ITER scenarios including a standard ELMy H-mode (15 MA discharge) and a hybrid scenario (12MA discharge). It has been found that fusion power production predicted in simulations of ITER discharges depends sensitively on the height of the H-mode temperature pedestal [1]. In order to study this effect, the NTCC PEDESTAL module [2] has been implemented in PTRANSP code to provide boundary conditions used for the computation of the projected performance of ITER. The PEDESTAL module computes both the temperature and width of the pedestal at the edge of type I ELMy H-mode discharges once the threshold conditions for the H-mode are satisfied. The anomalous transport in the plasma core is predicted using the GLF23 or MMM95 transport models. To facilitate the steering of lengthy PTRANSP computations, the PTRANSP code has been modified to allow changes in the transport model when simulations are restarted. The PTRANSP simulation results are compared with corresponding results obtained using other integrated modeling codes.[1] G. Bateman, T. Onjun and A.H. Kritz, Plasma Physics and Controlled Fusion, 45, 1939 (2003).[2] T. Onjun, G. Bateman, A.H. Kritz, and G. Hammett, Phys. Plasmas 9, 5018 (2002).

A fully non-linear multi-species Fokker–Planck–Landau collision operator for simulation of fusion plasma

DOE PAGES

Hager, Robert; Yoon, E. S.; Ku, S.; ...

2016-04-04

Fusion edge plasmas can be far from thermal equilibrium and require the use of a non-linear collision operator for accurate numerical simulations. The non-linear single-species Fokker–Planck–Landau collision operator developed by Yoon and Chang (2014) [9] is generalized to include multiple particle species. Moreover, the finite volume discretization used in this work naturally yields exact conservation of mass, momentum, and energy. The implementation of this new non-linear Fokker–Planck–Landau operator in the gyrokinetic particle-in-cell codes XGC1 and XGCa is described and results of a verification study are discussed. Finally, the numerical techniques that make our non-linear collision operator viable on high-performance computingmore » systems are described, including specialized load balancing algorithms and nested OpenMP parallelization. As a result, the collision operator's good weak and strong scaling behavior are shown.« less

Tritium well depth, tritium well time and sponge mechanism for reducing tritium retention

NASA Astrophysics Data System (ADS)

Deng, B. Q.; Li, Z. X.; Li, C. Y.; Feng, K. M.

2011-07-01

New simulation results are predicted in a fusion reactor operation process. They are somewhat similar to, but quite different from, the xenon poisoning effects resulting from fission-produced iodine during the restart-up process of a fission reactor. We obtained completely new results of tritium well depth and tritium well time in magnetic confinement fusion energy research area. This study is carried out to investigate the following: what will be the least amount of tritium storage required to start up a fusion reactor and how long the fusion reactor needs to be operated for achieving the tritium break-even during the initial start-up phase due to the finite tritium-breeding time, which is dependent on the tritium breeder, specific structure of the breeding zone, layout of the coolant flow pipes, tritium recovery scheme and applied extraction process, the tritium retention of plasma facing component (PFC) and other reactor components, unrecoverable tritium fraction in the breeder, leakage to the inertial gas container and the natural radioactive decay time constant. We describe these new issues and answer these problems by setting up and solving a set of equations, which are described by a dynamic subsystem model of tritium inventory evolution in a fusion experimental breeder (FEB). Reasonable results are obtained using our simulation model. It is found that the tritium well depth is about 0.319 kg and the tritium well time is approximately 235 full power operation days for the reference case of the designed FEB configuration, and it is also found that after one-year operation the tritium storage reaches 0.767 kg, which is more than the least amount of tritium storage required to start up another FEB-like fusion reactor. The results show that the tritium retention in the PFC is equivalent to 11.9% of tritium well depth that is fairly consistent with the result of 10-20% deduced from the integrated particle balance of European tokamaks. Based on our experimental and theoretical studies, some new mechanisms are proposed for reducing the tritium retention in PFC and structure materials of tritium-breeding blanket. In this paper, a qualitative analysis of the 'sponge effect' is carried out. The 'sponge effect' may help us to reduce tritium retention by ~20% in the PFC.

Magnetized Target Fusion At General Fusion: An Overview

NASA Astrophysics Data System (ADS)

Laberge, Michel; O'Shea, Peter; Donaldson, Mike; Delage, Michael; Fusion Team, General

2017-10-01

Magnetized Target Fusion (MTF) involves compressing an initial magnetically confined plasma on a timescale faster than the thermal confinement time of the plasma. If near adiabatic compression is achieved, volumetric compression of 350X or more of a 500 eV target plasma would achieve a final plasma temperature exceeding 10 keV. Interesting fusion gains could be achieved provided the compressed plasma has sufficient density and dwell time. General Fusion (GF) is developing a compression system using pneumatic pistons to collapse a cavity formed in liquid metal containing a magnetized plasma target. Low cost driver, straightforward heat extraction, good tritium breeding ratio and excellent neutron protection could lead to a practical power plant. GF (65 employees) has an active plasma R&D program including both full scale and reduced scale plasma experiments and simulation of both. Although pneumatic driven compression of full scale plasmas is the end goal, present compression studies use reduced scale plasmas and chemically accelerated aluminum liners. We will review results from our plasma target development, motivate and review the results of dynamic compression field tests and briefly describe the work to date on the pneumatic driver front.

Aperture tolerances for neutron-imaging systems in inertial confinement fusion.

PubMed

Ghilea, M C; Sangster, T C; Meyerhofer, D D; Lerche, R A; Disdier, L

2008-02-01

Neutron-imaging systems are being considered as an ignition diagnostic for the National Ignition Facility (NIF) [Hogan et al., Nucl. Fusion 41, 567 (2001)]. Given the importance of these systems, a neutron-imaging design tool is being used to quantify the effects of aperture fabrication and alignment tolerances on reconstructed neutron images for inertial confinement fusion. The simulations indicate that alignment tolerances of more than 1 mrad would introduce measurable features in a reconstructed image for both pinholes and penumbral aperture systems. These simulations further show that penumbral apertures are several times less sensitive to fabrication errors than pinhole apertures.

Sensor fusion for synthetic vision

NASA Technical Reports Server (NTRS)

Pavel, M.; Larimer, J.; Ahumada, A.

1991-01-01

Display methodologies are explored for fusing images gathered by millimeter wave sensors with images rendered from an on-board terrain data base to facilitate visually guided flight and ground operations in low visibility conditions. An approach to fusion based on multiresolution image representation and processing is described which facilitates fusion of images differing in resolution within and between images. To investigate possible fusion methods, a workstation-based simulation environment is being developed.

A comprehensive alpha-heating model for inertial confinement fusion

DOE Office of Scientific and Technical Information (OSTI.GOV)

Christopherson, A. R.; Betti, R.; Bose, A.

In this paper, a comprehensive model is developed to study alpha-heating in inertially confined plasmas. It describes the time evolution of a central low-density hot spot confined by a compressible shell, heated by fusion alphas, and cooled by radiation and thermal losses. The model includes the deceleration, stagnation, and burn phases of inertial confinement fusion implosions, and is valid for sub-ignited targets with ≤10× amplification of the fusion yield from alpha-heating. The results of radiation-hydrodynamic simulations are used to derive realistic initial conditions and dimensionless parameters for the model. It is found that most of the alpha energy (~90%) producedmore » before bang time is deposited within the hot spot mass, while a small fraction (~10%) drives mass ablation off the inner shell surface and its energy is recycled back into the hot spot. Of the bremsstrahlung radiation emission, ~40% is deposited in the hot spot, ~40% is recycled back in the hot spot by ablation off the shell, and ~20% leaves the hot spot. We show here that the hot spot, shocked shell, and outer shell trajectories from this analytical model are in good agreement with simulations. Finally, a detailed discussion of the effect of alpha-heating on the hydrodynamics is also presented.« less

A comprehensive alpha-heating model for inertial confinement fusion

NASA Astrophysics Data System (ADS)

Christopherson, A. R.; Betti, R.; Bose, A.; Howard, J.; Woo, K. M.; Campbell, E. M.; Sanz, J.; Spears, B. K.

2018-01-01

A comprehensive model is developed to study alpha-heating in inertially confined plasmas. It describes the time evolution of a central low-density hot spot confined by a compressible shell, heated by fusion alphas, and cooled by radiation and thermal losses. The model includes the deceleration, stagnation, and burn phases of inertial confinement fusion implosions, and is valid for sub-ignited targets with ≤10 × amplification of the fusion yield from alpha-heating. The results of radiation-hydrodynamic simulations are used to derive realistic initial conditions and dimensionless parameters for the model. It is found that most of the alpha energy (˜90%) produced before bang time is deposited within the hot spot mass, while a small fraction (˜10%) drives mass ablation off the inner shell surface and its energy is recycled back into the hot spot. Of the bremsstrahlung radiation emission, ˜40% is deposited in the hot spot, ˜40% is recycled back in the hot spot by ablation off the shell, and ˜20% leaves the hot spot. We show here that the hot spot, shocked shell, and outer shell trajectories from this analytical model are in good agreement with simulations. A detailed discussion of the effect of alpha-heating on the hydrodynamics is also presented.

A comprehensive alpha-heating model for inertial confinement fusion

DOE PAGES

Christopherson, A. R.; Betti, R.; Bose, A.; ...

2018-01-08

In this paper, a comprehensive model is developed to study alpha-heating in inertially confined plasmas. It describes the time evolution of a central low-density hot spot confined by a compressible shell, heated by fusion alphas, and cooled by radiation and thermal losses. The model includes the deceleration, stagnation, and burn phases of inertial confinement fusion implosions, and is valid for sub-ignited targets with ≤10× amplification of the fusion yield from alpha-heating. The results of radiation-hydrodynamic simulations are used to derive realistic initial conditions and dimensionless parameters for the model. It is found that most of the alpha energy (~90%) producedmore » before bang time is deposited within the hot spot mass, while a small fraction (~10%) drives mass ablation off the inner shell surface and its energy is recycled back into the hot spot. Of the bremsstrahlung radiation emission, ~40% is deposited in the hot spot, ~40% is recycled back in the hot spot by ablation off the shell, and ~20% leaves the hot spot. We show here that the hot spot, shocked shell, and outer shell trajectories from this analytical model are in good agreement with simulations. Finally, a detailed discussion of the effect of alpha-heating on the hydrodynamics is also presented.« less

Nonlinear Delta-f Simulations of Collective Effects in Intense Charged Particle Beams

NASA Astrophysics Data System (ADS)

Qin, Hong

2002-11-01

A nonlinear delta-f particle simulation method based on the Vlasov-Maxwell equations has been recently developed to study collective processes in high-intensity beams, where space-charge and magnetic self-field effects play a critical role in determining the nonlinear beam dynamics. Implemented in the Beam Equilibrium, Stability and Transport (BEST) code, the nonlinear delta-f method provides a low-noise and self-consistent tool for simulating collective interactions and nonlinear dynamics of high-intensity beams in modern and next- generation accelerators and storage rings, such as the Spallation Neutron Source, and heavy ion fusion drivers. Simulation results for the electron-proton two-stream instability in the Proton Storage Ring (PSR) experiment at Los Alamos National Laboratory agree well with experimental observations. Large-scale parallel simulations have also been carried out for the ion-electron two-stream instability in the very high-intensity heavy ion beams envisioned for heavy ion fusion applications. In both cases, the simulation results indicate that the dominant two-stream instability has a dipole-mode (hose-like) structure and can be stabilized by a modest axial momentum spread of the beam particles of less than 0.25collective processes in high-intensity beams, such as anisotropy-driven instabilities, collective eigenmode excitations for perturbations about stable beam equilibria, and the Darwin model for fully electromagnetic perturbations will also be discussed.

A new hyperspectral image compression paradigm based on fusion

NASA Astrophysics Data System (ADS)

Guerra, Raúl; Melián, José; López, Sebastián.; Sarmiento, Roberto

2016-10-01

The on-board compression of remote sensed hyperspectral images is an important task nowadays. One of the main difficulties is that the compression of these images must be performed in the satellite which carries the hyperspectral sensor. Hence, this process must be performed by space qualified hardware, having area, power and speed limitations. Moreover, it is important to achieve high compression ratios without compromising the quality of the decompress image. In this manuscript we proposed a new methodology for compressing hyperspectral images based on hyperspectral image fusion concepts. The proposed compression process has two independent steps. The first one is to spatially degrade the remote sensed hyperspectral image to obtain a low resolution hyperspectral image. The second step is to spectrally degrade the remote sensed hyperspectral image to obtain a high resolution multispectral image. These two degraded images are then send to the earth surface, where they must be fused using a fusion algorithm for hyperspectral and multispectral image, in order to recover the remote sensed hyperspectral image. The main advantage of the proposed methodology for compressing remote sensed hyperspectral images is that the compression process, which must be performed on-board, becomes very simple, being the fusion process used to reconstruct image the more complex one. An extra advantage is that the compression ratio can be fixed in advanced. Many simulations have been performed using different fusion algorithms and different methodologies for degrading the hyperspectral image. The results obtained in the simulations performed corroborate the benefits of the proposed methodology.

Enhanced EDX images by fusion of multimodal SEM images using pansharpening techniques.

PubMed

Franchi, G; Angulo, J; Moreaud, M; Sorbier, L

2018-01-01

The goal of this paper is to explore the potential interest of image fusion in the context of multimodal scanning electron microscope (SEM) imaging. In particular, we aim at merging the backscattered electron images that usually have a high spatial resolution but do not provide enough discriminative information to physically classify the nature of the sample, with energy-dispersive X-ray spectroscopy (EDX) images that have discriminative information but a lower spatial resolution. The produced images are named enhanced EDX. To achieve this goal, we have compared the results obtained with classical pansharpening techniques for image fusion with an original approach tailored for multimodal SEM fusion of information. Quantitative assessment is obtained by means of two SEM images and a simulated dataset produced by a software based on PENELOPE. © 2017 The Authors Journal of Microscopy © 2017 Royal Microscopical Society.

High-Gain High-Field Fusion Plasma

PubMed Central

Li, Ge

2015-01-01

A Faraday wheel (FW)—an electric generator of constant electrical polarity that produces huge currents—could be implemented in an existing tokamak to study high-gain high-field (HGHF) fusion plasma, such as the Experimental Advanced Superconducting Tokamak (EAST). HGHF plasma can be realized in EAST by updating its pulsed-power system to compress plasma in two steps by induction fields; high gains of the Lawson trinity parameter and fusion power are both predicted by formulating the HGHF plasma. Both gain rates are faster than the decrease rate of the plasma volume. The formulation is checked by earlier ATC tests. Good agreement between theory and tests indicates that scaling to over 10 T at EAST may be possible by two-step compressions with a compression ratio of the minor radius of up to 3. These results point to a quick new path of fusion plasma study, i.e., simulating the Sun by EAST. PMID:26507314

Modelling third harmonic ion cyclotron acceleration of deuterium beams for JET fusion product studies experiments

NASA Astrophysics Data System (ADS)

Schneider, M.; Johnson, T.; Dumont, R.; Eriksson, J.; Eriksson, L.-G.; Giacomelli, L.; Girardo, J.-B.; Hellsten, T.; Khilkevitch, E.; Kiptily, V. G.; Koskela, T.; Mantsinen, M.; Nocente, M.; Salewski, M.; Sharapov, S. E.; Shevelev, A. E.; Contributors, JET

2016-11-01

Recent JET experiments have been dedicated to the studies of fusion reactions between deuterium (D) and Helium-3 (3He) ions using neutral beam injection (NBI) in synergy with third harmonic ion cyclotron radio-frequency heating (ICRH) of the beam. This scenario generates a fast ion deuterium tail enhancing DD and D3He fusion reactions. Modelling and measuring the fast deuterium tail accurately is essential for quantifying the fusion products. This paper presents the modelling of the D distribution function resulting from the NBI+ICRF heating scheme, reinforced by a comparison with dedicated JET fast ion diagnostics, showing an overall good agreement. Finally, a sawtooth activity for these experiments has been observed and interpreted using SPOT/RFOF simulations in the framework of Porcelli’s theoretical model, where NBI+ICRH accelerated ions are found to have a strong stabilizing effect, leading to monster sawteeth.

Simulation of wave interactions with MHD

NASA Astrophysics Data System (ADS)

Batchelor, D.; Alba, C.; Bateman, G.; Bernholdt, D.; Berry, L.; Bonoli, P.; Bramley, R.; Breslau, J.; Chance, M.; Chen, J.; Choi, M.; Elwasif, W.; Fu, G.; Harvey, R.; Jaeger, E.; Jardin, S.; Jenkins, T.; Keyes, D.; Klasky, S.; Kruger, S.; Ku, L.; Lynch, V.; McCune, D.; Ramos, J.; Schissel, D.; Schnack, D.; Wright, J.

2008-07-01

The broad scientific objectives of the SWIM (Simulation 01 Wave Interaction with MHD) project are twofold: (1) improve our understanding of interactions that both radio frequency (RF) wave and particle sources have on extended-MHD phenomena, and to substantially improve our capability for predicting and optimizing the performance of burning plasmas in devices such as ITER: and (2) develop an integrated computational system for treating multiphysics phenomena with the required flexibility and extensibility to serve as a prototype for the Fusion Simulation Project. The Integrated Plasma Simulator (IPS) has been implemented. Presented here are initial physics results on RP effects on MHD instabilities in tokamaks as well as simulation results for tokamak discharge evolution using the IPS.

Three-dimensional simulations of plasma turbulence in the RFX-mod scrape-off layer and comparison with experimental measurements

NASA Astrophysics Data System (ADS)

Riva, Fabio; Vianello, Nicola; Spolaore, Monica; Ricci, Paolo; Cavazzana, Roberto; Marrelli, Lionello; Spagnolo, Silvia

2018-02-01

The tokamak scrape-off layer (SOL) plasma dynamics is investigated in a circular limiter configuration with a low edge safety factor. Focusing on the experimental parameters of two ohmic tokamak inner-wall limited plasma discharges in RFX-mod [Sonato et al., Fusion Eng. Des. 74, 97 (2005)], nonlinear SOL plasma simulations are performed with the GBS code [Ricci et al., Plasma Phys. Controlled Fusion 54, 124047 (2012)]. The numerical results are compared with the experimental measurements, assessing the reliability of the GBS model in describing the RFX-mod SOL plasma dynamics. It is found that the simulations are able to quantitatively reproduce the RFX-mod experimental measurements of the electron plasma density, electron temperature, and ion saturation current density (jsat) equilibrium profiles. Moreover, there are indications that the turbulent transport is driven by the same instability in the simulations and in the experiment, with coherent structures having similar statistical properties. On the other hand, it is found that the simulation results are not able to correctly reproduce the floating potential equilibrium profile and the jsat fluctuation level. It is likely that these discrepancies are, at least in part, related to simulating only the tokamak SOL region, without including the plasma dynamics inside the last close flux surface, and to the limits of applicability of the drift approximation. The turbulence drive is then identified from the nonlinear simulations and with the linear theory. It results that the inertial drift wave is the instability driving most of the turbulent transport in the considered discharges.

Condorcet and borda count fusion method for ligand-based virtual screening

PubMed Central

2014-01-01

Background It is known that any individual similarity measure will not always give the best recall of active molecule structure for all types of activity classes. Recently, the effectiveness of ligand-based virtual screening approaches can be enhanced by using data fusion. Data fusion can be implemented using two different approaches: group fusion and similarity fusion. Similarity fusion involves searching using multiple similarity measures. The similarity scores, or ranking, for each similarity measure are combined to obtain the final ranking of the compounds in the database. Results The Condorcet fusion method was examined. This approach combines the outputs of similarity searches from eleven association and distance similarity coefficients, and then the winner measure for each class of molecules, based on Condorcet fusion, was chosen to be the best method of searching. The recall of retrieved active molecules at top 5% and significant test are used to evaluate our proposed method. The MDL drug data report (MDDR), maximum unbiased validation (MUV) and Directory of Useful Decoys (DUD) data sets were used for experiments and were represented by 2D fingerprints. Conclusions Simulated virtual screening experiments with the standard two data sets show that the use of Condorcet fusion provides a very simple way of improving the ligand-based virtual screening, especially when the active molecules being sought have a lowest degree of structural heterogeneity. However, the effectiveness of the Condorcet fusion was increased slightly when structural sets of high diversity activities were being sought. PMID:24883114

Effects of Mars Atmosphere on Arc Welds: Phase 2

NASA Technical Reports Server (NTRS)

Courtright, Z. S.

2018-01-01

Gas tungsten arc welding (GTAW) is a vital fusion welding process widely used throughout the aerospace industry. Its use may be critical for the repair or manufacture of systems, rockets, or facilities on the Martian surface. Aluminum alloy AA2219-T87 and titanium alloy Ti-6Al-4V butt welds have been investigated for weldability and weld properties in a simulated Martian gas environment. The resulting simulated Martian welds were compared to welds made in a terrestrial atmosphere, all of which used argon shielding gas. It was found that GTAW is a process that may be used in a Martian gas environment, not accounting for pressure and gravitational effects, as long as adequate argon shielding gas is used to protect the weld metal. Simulated Martian welds exhibited higher hardness in all cases and higher tensile strength in the case of AA2219-T87. This has been attributed to the absorption of carbon into the fusion zone, causing carbide precipitates to form. These precipitates may act to pin dislocations upon tensile testing of AA2219-T87. Dissolved carbon may have also led to carburization, which may have caused the increase in hardness within the fusion zone of the welds. Based on the results of this experiment and other similar experiments, GTAW appears to be a promising process for welding in a Martian gas environment. Additional funding and experimentation is necessary to determine the effects of the low pressure and low gravity environment found on Mars on GTAW.

Integrated navigation fusion strategy of INS/UWB for indoor carrier attitude angle and position synchronous tracking.

PubMed

Fan, Qigao; Wu, Yaheng; Hui, Jing; Wu, Lei; Yu, Zhenzhong; Zhou, Lijuan

2014-01-01

In some GPS failure conditions, positioning for mobile target is difficult. This paper proposed a new method based on INS/UWB for attitude angle and position synchronous tracking of indoor carrier. Firstly, error model of INS/UWB integrated system is built, including error equation of INS and UWB. And combined filtering model of INS/UWB is researched. Simulation results show that the two subsystems are complementary. Secondly, integrated navigation data fusion strategy of INS/UWB based on Kalman filtering theory is proposed. Simulation results show that FAKF method is better than the conventional Kalman filtering. Finally, an indoor experiment platform is established to verify the integrated navigation theory of INS/UWB, which is geared to the needs of coal mine working environment. Static and dynamic positioning results show that the INS/UWB integrated navigation system is stable and real-time, positioning precision meets the requirements of working condition and is better than any independent subsystem.

Accuracy and convergence of coupled finite-volume/Monte Carlo codes for plasma edge simulations of nuclear fusion reactors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ghoos, K., E-mail: kristel.ghoos@kuleuven.be; Dekeyser, W.; Samaey, G.

2016-10-01

The plasma and neutral transport in the plasma edge of a nuclear fusion reactor is usually simulated using coupled finite volume (FV)/Monte Carlo (MC) codes. However, under conditions of future reactors like ITER and DEMO, convergence issues become apparent. This paper examines the convergence behaviour and the numerical error contributions with a simplified FV/MC model for three coupling techniques: Correlated Sampling, Random Noise and Robbins Monro. Also, practical procedures to estimate the errors in complex codes are proposed. Moreover, first results with more complex models show that an order of magnitude speedup can be achieved without any loss in accuracymore » by making use of averaging in the Random Noise coupling technique.« less

Evaluation of Effective Parameters on Quality of Magnetic Resonance Imaging-computed Tomography Image Fusion in Head and Neck Tumors for Application in Treatment Planning

PubMed Central

Shirvani, Atefeh; Jabbari, Keyvan; Amouheidari, Alireza

2017-01-01

Background: In radiation therapy, computed tomography (CT) simulation is used for treatment planning to define the location of tumor. Magnetic resonance imaging (MRI)-CT image fusion leads to more efficient tumor contouring. This work tried to identify the practical issues for the combination of CT and MRI images in real clinical cases. The effect of various factors is evaluated on image fusion quality. Materials and Methods: In this study, the data of thirty patients with brain tumors were used for image fusion. The effect of several parameters on possibility and quality of image fusion was evaluated. These parameters include angles of the patient's head on the bed, slices thickness, slice gap, and height of the patient's head. Results: According to the results, the first dominating factor on quality of image fusion was the difference slice gap between CT and MRI images (cor = 0.86, P < 0.005) and second factor was the angle between CT and MRI slice in the sagittal plane (cor = 0.75, P < 0.005). In 20% of patients, this angle was more than 28° and image fusion was not efficient. In 17% of patients, difference slice gap in CT and MRI was >4 cm and image fusion quality was <25%. Conclusion: The most important problem in image fusion is that MRI images are taken without regard to their use in treatment planning. In general, parameters related to the patient position during MRI imaging should be chosen to be consistent with CT images of the patient in terms of location and angle. PMID:29387672

Validating Inertial Confinement Fusion (ICF) predictive capability using perturbed capsules

NASA Astrophysics Data System (ADS)

Schmitt, Mark; Magelssen, Glenn; Tregillis, Ian; Hsu, Scott; Bradley, Paul; Dodd, Evan; Cobble, James; Flippo, Kirk; Offerman, Dustin; Obrey, Kimberly; Wang, Yi-Ming; Watt, Robert; Wilke, Mark; Wysocki, Frederick; Batha, Steven

2009-11-01

Achieving ignition on NIF is a monumental step on the path toward utilizing fusion as a controlled energy source. Obtaining robust ignition requires accurate ICF models to predict the degradation of ignition caused by heterogeneities in capsule construction and irradiation. LANL has embarked on a project to induce controlled defects in capsules to validate our ability to predict their effects on fusion burn. These efforts include the validation of feature-driven hydrodynamics and mix in a convergent geometry. This capability is needed to determine the performance of capsules imploded under less-than-optimum conditions on future IFE facilities. LANL's recently initiated Defect Implosion Experiments (DIME) conducted at Rochester's Omega facility are providing input for these efforts. Recent simulation and experimental results will be shown.

Magnetized Target Fusion

NASA Technical Reports Server (NTRS)

Griffin, Steven T.

2002-01-01

Magnetized target fusion (MTF) is under consideration as a means of building a low mass, high specific impulse, and high thrust propulsion system for interplanetary travel. This unique combination is the result of the generation of a high temperature plasma by the nuclear fusion process. This plasma can then be deflected by magnetic fields to provide thrust. Fusion is initiated by a small traction of the energy generated in the magnetic coils due to the plasma's compression of the magnetic field. The power gain from a fusion reaction is such that inefficiencies due to thermal neutrons and coil losses can be overcome. Since the fusion reaction products are directly used for propulsion and the power to initiate the reaction is directly obtained from the thrust generation, no massive power supply for energy conversion is required. The result should be a low engine mass, high specific impulse and high thrust system. The key is to successfully initiate fusion as a proof-of-principle for this application. Currently MSFC is implementing MTF proof-of-principle experiments. This involves many technical details and ancillary investigations. Of these, selected pertinent issues include the properties, orientation and timing of the plasma guns and the convergence and interface development of the "pusher" plasma. Computer simulations of the target plasma's behavior under compression and the convergence and mixing of the gun plasma are under investigation. This work is to focus on the gun characterization and development as it relates to plasma initiation and repeatability.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dahlburg, Jill; Corones, James; Batchelor, Donald

Fusion is potentially an inexhaustible energy source whose exploitation requires a basic understanding of high-temperature plasmas. The development of a science-based predictive capability for fusion-relevant plasmas is a challenge central to fusion energy science, in which numerical modeling has played a vital role for more than four decades. A combination of the very wide range in temporal and spatial scales, extreme anisotropy, the importance of geometric detail, and the requirement of causality which makes it impossible to parallelize over time, makes this problem one of the most challenging in computational physics. Sophisticated computational models are under development for many individualmore » features of magnetically confined plasmas and increases in the scope and reliability of feasible simulations have been enabled by increased scientific understanding and improvements in computer technology. However, full predictive modeling of fusion plasmas will require qualitative improvements and innovations to enable cross coupling of a wider variety of physical processes and to allow solution over a larger range of space and time scales. The exponential growth of computer speed, coupled with the high cost of large-scale experimental facilities, makes an integrated fusion simulation initiative a timely and cost-effective opportunity. Worldwide progress in laboratory fusion experiments provides the basis for a recent FESAC recommendation to proceed with a burning plasma experiment (see FESAC Review of Burning Plasma Physics Report, September 2001). Such an experiment, at the frontier of the physics of complex systems, would be a huge step in establishing the potential of magnetic fusion energy to contribute to the world’s energy security. An integrated simulation capability would dramatically enhance the utilization of such a facility and lead to optimization of toroidal fusion plasmas in general. This science-based predictive capability, which was cited in the FESAC integrated planning document (IPPA, 2000), represents a significant opportunity for the DOE Office of Science to further the understanding of fusion plasmas to a level unparalleled worldwide.« less

Driver fatigue detection through multiple entropy fusion analysis in an EEG-based system.

PubMed

Min, Jianliang; Wang, Ping; Hu, Jianfeng

2017-01-01

Driver fatigue is an important contributor to road accidents, and fatigue detection has major implications for transportation safety. The aim of this research is to analyze the multiple entropy fusion method and evaluate several channel regions to effectively detect a driver's fatigue state based on electroencephalogram (EEG) records. First, we fused multiple entropies, i.e., spectral entropy, approximate entropy, sample entropy and fuzzy entropy, as features compared with autoregressive (AR) modeling by four classifiers. Second, we captured four significant channel regions according to weight-based electrodes via a simplified channel selection method. Finally, the evaluation model for detecting driver fatigue was established with four classifiers based on the EEG data from four channel regions. Twelve healthy subjects performed continuous simulated driving for 1-2 hours with EEG monitoring on a static simulator. The leave-one-out cross-validation approach obtained an accuracy of 98.3%, a sensitivity of 98.3% and a specificity of 98.2%. The experimental results verified the effectiveness of the proposed method, indicating that the multiple entropy fusion features are significant factors for inferring the fatigue state of a driver.

Effect of lordosis angle change after lumbar/lumbosacral fusion on sacrum angular displacement: a finite element study.

PubMed

Mao, Ningfang; Shi, Jian; He, Dawei; Xie, Yang; Bai, Yushu; Wei, Xianzhao; Shi, Zhicai; Li, Ming

2014-11-01

To assess and characterize the sacrum angular displacements in response to lumbar lordosis after lumbar/lumbosacral fusion. A finite element model of the lower lumbar spine-pelvis was established and used to simulate the posterior fusion at L3-L5 and L4-S1. The lordosis angle in the fusion segments was set to five different conditions with respect to the intact model: 10° less than intact, 5° less than intact, same as intact, 5° more than intact, and 10° more than intact. Variations of the sacrum angular displacements with lordosis changes were analyzed under loading setting of axial compression, flexion, extension, lateral bending, and axial rotation. Compared with the intact lordosis, both increased and decreased lumbar lordosis angles caused the sacrum angular displacements to be increased. The lordosis angle increased by 10° induced the most substantial increase in sacrum angular displacements. In addition, the sacrum angular displacements of the L4-S1 fusion model at different lordosis angles were higher than those of the L3-L5 fusion model. The sacrum angular displacements occur as a result of the fusion surgery (L4-S1) and the changes in lumbar lordosis.

Sacroiliac Joint Fusion Minimally Affects Adjacent Lumbar Segment Motion: A Finite Element Study

PubMed Central

Kiapour, Ali; Yerby, Scott A.; Goel, Vijay K.

2015-01-01

Background Adjacent segment disease is a recognized consequence of fusion in the spinal column. Fusion of the sacroiliac joint is an effective method of pain reduction. Although effective, the consequences of sacroiliac joint fusion and the potential for adjacent segment disease for the adjacent lumbar spinal levels is unknown. The objective of this study was to quantify the change in range of motion of the sacroiliac joint and the adjacent lumbar spinal motion segments due to sacroiliac joint fusion and compare these changes to previous literature to assess the potential for adjacent segment disease in the lumbar spine. Methods An experimentally validated finite element model of the lumbar spine and pelvis was used to simulate a fusion of the sacroiliac joint using three laterally placed triangular implants (iFuse Implant System, SI-BONE, Inc., San Jose, CA). The range of motion of the sacroiliac joint and the adjacent lumbar spinal motion segments were calculated using a hybrid loading protocol and compared with the intact range of motion in flexion, extension, lateral bending, and axial rotation. Results The range of motions of the treated sacroiliac joints were reduced in flexion, extension, lateral bending, and axial rotation, by 56.6%, 59.5%, 27.8%, and 53.3%, respectively when compared with the intact condition. The stiffening of the sacroiliac joint resulted in increases at the adjacent lumbar motion segment (L5-S1) for flexion, extension, lateral bending, and axial rotation, of 3.0%, 3.7%, 1.1%, and 4.6%, respectively. Conclusions Fusion of the sacroiliac joint resulted in substantial (> 50%) reductions in flexion, extension, and axial rotation of the sacroiliac joint with minimal (< 5%) increases in range of motion in the lumbar spine. Although the predicted increases in lumbar range of motion are minimal after sacroiliac joint fusion, the long-term clinical results remain to be investigated. PMID:26767156

Optimally Distributed Kalman Filtering with Data-Driven Communication †

PubMed Central

Dormann, Katharina

2018-01-01

For multisensor data fusion, distributed state estimation techniques that enable a local processing of sensor data are the means of choice in order to minimize storage and communication costs. In particular, a distributed implementation of the optimal Kalman filter has recently been developed. A significant disadvantage of this algorithm is that the fusion center needs access to each node so as to compute a consistent state estimate, which requires full communication each time an estimate is requested. In this article, different extensions of the optimally distributed Kalman filter are proposed that employ data-driven transmission schemes in order to reduce communication expenses. As a first relaxation of the full-rate communication scheme, it can be shown that each node only has to transmit every second time step without endangering consistency of the fusion result. Also, two data-driven algorithms are introduced that even allow for lower transmission rates, and bounds are derived to guarantee consistent fusion results. Simulations demonstrate that the data-driven distributed filtering schemes can outperform a centralized Kalman filter that requires each measurement to be sent to the center node. PMID:29596392

Study of Plasma Liner Driven Magnetized Target Fusion Via Advanced Simulations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Samulyak, Roman V.; Brookhaven National Lab.; Parks, Paul

The feasibility of the plasma liner driven Magnetized Target Fusion (MTF) via terascale numerical simulations will be assessed. In the MTF concept, a plasma liner, formed by merging of a number (60 or more) of radial, highly supersonic plasma jets, implodes on the target in the form of two compact plasma toroids, and compresses it to conditions of the fusion ignition. By avoiding major difficulties associated with both the traditional laser driven inertial confinement fusion and solid liner driven MTF, the plasma liner driven MTF potentially provides a low-cost and fast R&D path towards the demonstration of practical fusion energy.more » High fidelity numerical simulations of full nonlinear models associated with the plasma liner MTF using state-of-art numerical algorithms and terascale computing are necessary in order to resolve uncertainties and provide guidance for future experiments. At Stony Brook University, we have developed unique computational capabilities that ideally suite the MTF problem. The FronTier code, developed in collaboration with BNL and LANL under DOE funding including SciDAC for the simulation of 3D multi-material hydro and MHD flows, has beenbenchmarked and used for fundamental and engineering problems in energy science applications. We have performed 3D simulations of converging supersonic plasma jets, their merger and the formation of the plasma liner, and a study of the corresponding oblique shock problem. We have studied the implosion of the plasma liner on the magnetized plasma target by resolving Rayleigh-Taylor instabilities in 2D and 3D and other relevant physics and estimate thermodynamic conditions of the target at the moment of maximum compression and the hydrodynamic efficiency of the method.« less

Projection parameters for zirconia-alumina-ceria coatings made by flame spraying from results of numerical simulation

NASA Astrophysics Data System (ADS)

Rodríguez, L.; Ferrer, M.; Vargas, F.; Peña, G.

2017-12-01

A numerical simulation was performed with the software Jets et Poudres, the results let choose the parameters to deposit zirconia-alumina-ceria coatings of different composition on substrates of red clay, by thermal spraying with the oxyacetylene flame to obtain homogeneous coatings with good adhesion to the substrate. The effect of the projection distance (7, 10 and 12cm) between the substrate and the torch, the fusion percentage of particles and the K-Sommerfeld number was determined. This number is dimensionless and is affected by the projection distance and by the chemical composition of the particles. For a projection distance of 9cm, the fusion percentage of the particles varies between 83.8% and 100%, and the K-Sommerfeld number between 47.3 and 50 for the different compounds. This makes possible to obtain uniform coatings with good wettability, therefore, good adhesion to the substrate, while for the distance of 7cm the fusion percentage varies between 22% and 38%, due to the short time of the particles in the flame which causes low adhesion, when the projection distance is 12cm the particles do not have sufficient kinetic energy to reach the substrate and therefore the coating is not deposited.

Molecular dynamics simulation of the evolution of hydrophobic defects in one monolayer of a phosphatidylcholine bilayer: relevance for membrane fusion mechanisms.

PubMed Central

Tieleman, D Peter; Bentz, Joe

2002-01-01

The spontaneous formation of the phospholipid bilayer underlies the permeability barrier function of the biological membrane. Tears or defects that expose water to the acyl chains are spontaneously healed by lipid lateral diffusion. However, mechanical barriers, e.g., protein aggregates held in place, could sustain hydrophobic defects. Such defects have been postulated to occur in processes such as membrane fusion. This gives rise to a new question in bilayer structure: What do the lipids do in the absence of lipid lateral diffusion to minimize the free energy of a hydrophobic defect? As a first step to understand this rather fundamental question about bilayer structure, we performed molecular dynamic simulations of up to 10 ns of a planar bilayer from which lipids have been deleted randomly from one monolayer. In one set of simulations, approximately one-half of the lipids in the defect monolayer were restrained to form a mechanical barrier. In the second set, lipids were free to diffuse around. The question was simply whether the defects caused by removing a lipid would aggregate together, forming a large hydrophobic cavity, or whether the membrane would adjust in another way. When there are no mechanical barriers, the lipids in the defect monolayer simply spread out and thin with little effect on the other intact monolayer. In the presence of a mechanical barrier, the behavior of the lipids depends on the size of the defect. When 3 of 64 lipids are removed, the remaining lipids adjust the lower one-half of their chains, but the headgroup structure changes little and the intact monolayer is unaffected. When 6 to 12 lipids are removed, the defect monolayer thins, lipid disorder increases, and lipids from the intact monolayer move toward the defect monolayer. Whereas this is a highly simplified model of a fusion site, this engagement of the intact monolayer into the fusion defect is strikingly consistent with recent results for influenza hemagglutinin mediated fusion. PMID:12202375

Adaptive multiple super fast simulated annealing for stochastic microstructure reconstruction

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ryu, Seun; Lin, Guang; Sun, Xin

2013-01-01

Fast image reconstruction from statistical information is critical in image fusion from multimodality chemical imaging instrumentation to create high resolution image with large domain. Stochastic methods have been used widely in image reconstruction from two point correlation function. The main challenge is to increase the efficiency of reconstruction. A novel simulated annealing method is proposed for fast solution of image reconstruction. Combining the advantage of very fast cooling schedules, dynamic adaption and parallelization, the new simulation annealing algorithm increases the efficiencies by several orders of magnitude, making the large domain image fusion feasible.

The biomechanics of a multilevel lumbar spine hybrid using nucleus replacement in conjunction with fusion.

PubMed

Dahl, Michael C; Ellingson, Arin M; Mehta, Hitesh P; Huelman, Justin H; Nuckley, David J

2013-02-01

Degenerative disc disease is commonly a multilevel pathology with varying deterioration severity. The use of fusion on multiple levels can significantly affect functionality and has been linked to persistent adjacent disc degeneration. A hybrid approach of fusion and nucleus replacement (NR) has been suggested as a solution for mildly degenerated yet painful levels adjacent to fusion. To compare the biomechanical metrics of different hybrid implant constructs, hypothesizing that an NR+fusion hybrid would be similar to a single-level fusion and perform more naturally compared with a two-level fusion. A cadaveric in vitro repeated-measures study was performed to evaluate a multilevel lumbar NR+fusion hybrid. Eight cadaveric spines (L3-S1) were tested in a Spine Kinetic Simulator (Instron, Norwood, MA, USA). Pure moments of 8 Nm were applied in flexion/extension, lateral bending, and axial rotation as well as compression loading. Specimens were tested intact; fused (using transforaminal lumbar interbody fusion instrumentation with posterior rods) at L5-S1; with a nuclectomy at L4-L5 including fusion at L5-S1; with NR at L4-L5 including fusion at L5-S1; and finally with a two-level fusion spanning L4-S1. Repeated-measures analysis of variance and corrected t tests were used to statistically compare outcomes. The NR+fusion hybrid and single-level fusion exhibited no statistical differences for range of motion (ROM), stiffness, neutral zone, and intradiscal pressure in all loading directions. Compared with two-level fusion, the hybrid affords the construct 41.9% more ROM on average. Two-level fusion stiffness was statistically higher than all other constructs and resulted in significantly lower ROM in flexion, extension, and lateral bending. The hybrid construct produced approximately half of the L3-L4 adjacent-level pressures as the two-level fusion case while generating similar pressures to the single-level fusion case. These data portend more natural functional outcomes and fewer adjacent disc complications for a multilevel NR+fusion hybrid compared with the classical two-level fusion. Copyright © 2013 Elsevier Inc. All rights reserved.

Simulating Astrophysical Jets with Inertial Confinement Fusion Machines

NASA Astrophysics Data System (ADS)

Blue, Brent

2005-10-01

Large-scale directional outflows of supersonic plasma, also known as `jets', are ubiquitous phenomena in astrophysics. The traditional approach to understanding such phenomena is through theoretical analysis and numerical simulations. However, theoretical analysis might not capture all the relevant physics and numerical simulations have limited resolution and fail to scale correctly in Reynolds number and perhaps other key dimensionless parameters. Recent advances in high energy density physics using large inertial confinement fusion devices now allow controlled laboratory experiments on macroscopic volumes of plasma of direct relevance to astrophysics. This talk will present an overview of these facilities as well as results from current laboratory astrophysics experiments designed to study hydrodynamic jets and Rayleigh-Taylor mixing. This work is performed under the auspices of the U. S. DOE by Lawrence Livermore National Laboratory under Contract No. W-7405-ENG-48, Los Alamos National Laboratory under Contract No. W-7405-ENG-36, and the Laboratory for Laser Energetics under Contract No. DE-FC03-92SF19460.

Investigation of Joint Visibility Between SAR and Optical Images of Urban Environments

NASA Astrophysics Data System (ADS)

Hughes, L. H.; Auer, S.; Schmitt, M.

2018-05-01

In this paper, we present a work-flow to investigate the joint visibility between very-high-resolution SAR and optical images of urban scenes. For this task, we extend the simulation framework SimGeoI to enable a simulation of individual pixels rather than complete images. Using the extended SimGeoI simulator, we carry out a case study using a TerraSAR-X staring spotlight image and a Worldview-2 panchromatic image acquired over the city of Munich, Germany. The results of this study indicate that about 55 % of the scene are visible in both images and are thus suitable for matching and data fusion endeavours, while about 25 % of the scene are affected by either radar shadow or optical occlusion. Taking the image acquisition parameters into account, our findings can provide support regarding the definition of upper bounds for image fusion tasks, as well as help to improve acquisition planning with respect to different application goals.

Laser-Plasma Interactions on NIKE and the Fusion Test Facility

NASA Astrophysics Data System (ADS)

Phillips, Lee; Weaver, James

2008-11-01

Recent proposed designs for a Fusion Test Facility (FTF) (Obenchain et al., Phys. Plasmas 13 056320 (2006)) for direct-drive ICF targets for energy applications involve high implosion velocities combined with higher laser irradiances. The use of high irradiances increases the likelihood of deleterious laser plasma instabilities (LPI) but the proposed use of a 248 nm KrF laser to drive these targets is expected to minimize the LPI risk. We examine, using simulation results from NRL's FAST hydrocode, the proposed operational regimes of the FTF in relation to the thresholds for the SRS, SBS, and 2-plasmon instabilities. Simulations are also used to help design and interpret ongoing experiments being conducted at NRL's NIKE facility for the purpose of generating and studying LPI. Target geometries and laser pulseshapes were devised in order to create plasma conditions with long scalelengths and low electron temperatures that allow the growth of parametric instabilities. These simulations include the effects of finite beam angles through the use of raytracing.

Apparatus and method for simulating material damage from a fusion reactor

DOEpatents

Smith, Dale L.; Greenwood, Lawrence R.; Loomis, Benny A.

1989-01-01

An apparatus and method for simulating a fusion environment on a first wall or blanket structure. A material test specimen is contained in a capsule made of a material having a low hydrogen solubility and permeability. The capsule is partially filled with a lithium solution, such that the test specimen is encapsulated by the lithium. The capsule is irradiated by a fast fission neutron source.

Apparatus and method for simulating material damage from a fusion reactor

DOEpatents

Smith, D.L.; Greenwood, L.R.; Loomis, B.A.

1988-05-20

This paper discusses an apparatus and method for simulating a fusion environment on a first wall or blanket structure. A material test specimen is contained in a capsule made of a material having a low hydrogen solubility and permeability. The capsule is partially filled with a lithium solution, such that the test specimen is encapsulated by the lithium. The capsule is irradiated by a fast fission neutron source.

Apparatus and method for simulating material damage from a fusion reactor

DOEpatents

Smith, Dale L.; Greenwood, Lawrence R.; Loomis, Benny A.

1989-03-07

An apparatus and method for simulating a fusion environment on a first wall or blanket structure. A material test specimen is contained in a capsule made of a material having a low hydrogen solubility and permeability. The capsule is partially filled with a lithium solution, such that the test specimen is encapsulated by the lithium. The capsule is irradiated by a fast fission neutron source.

Biomechanical Evaluation of a Novel Apatite-Wollastonite Ceramic Cage Design for Lumbar Interbody Fusion: A Finite Element Model Study

PubMed Central

Şenköylü, Alpaslan; Aktaş, Erdem; Sarıkaya, Baran; Sipahioğlu, Serkan; Gürbüz, Rıza; Timuçin, Muharrem

2018-01-01

Objectives Cage design and material properties play a crucial role in the long-term results, since interbody fusions using intervertebral cages have become one of the basic procedures in spinal surgery. Our aim is to design a novel Apatite-Wollastonite interbody fusion cage and evaluate its biomechanical behavior in silico in a segmental spinal model. Materials and Methods Mechanical properties for the Apatite-Wollastonite bioceramic cages were obtained by fitting finite element results to the experimental compression behavior of a cage prototype. The prototype was made from hydroxyapatite, pseudowollastonite, and frit by sintering. The elastic modulus of the material was found to be 32 GPa. Three intact lumbar vertebral segments were modelled with the ANSYS 12.0.1 software and this model was modified to simulate a Posterior Lumbar Interbody Fusion. Four cage designs in different geometries were analyzed in silico under axial loading, flexion, extension, and lateral bending. Results The K2 design had the best overall biomechanical performance for the loads considered. Maximum cage stress recorded was 36.7 MPa in compression after a flexion load, which was within the biomechanical limits of the cage. Conclusion Biomechanical analyses suggest that K2 bioceramic cage is an optimal design and reveals essential material properties for a stable interbody fusion. PMID:29581974

Particle-in-cell simulations of the plasma interaction with poloidal gaps in the ITER divertor outer vertical target

NASA Astrophysics Data System (ADS)

Komm, M.; Gunn, J. P.; Dejarnac, R.; Pánek, R.; Pitts, R. A.; Podolník, A.

2017-12-01

Predictive modelling of the heat flux distribution on ITER tungsten divertor monoblocks is a critical input to the design choice for component front surface shaping and for the understanding of power loading in the case of small-scale exposed edges. This paper presents results of particle-in-cell (PIC) simulations of plasma interaction in the vicinity of poloidal gaps between monoblocks in the high heat flux areas of the ITER outer vertical target. The main objective of the simulations is to assess the role of local electric fields which are accounted for in a related study using the ion orbit approach including only the Lorentz force (Gunn et al 2017 Nucl. Fusion 57 046025). Results of the PIC simulations demonstrate that even if in some cases the electric field plays a distinct role in determining the precise heat flux distribution, when heat diffusion into the bulk material is taken into account, the thermal responses calculated using the PIC or ion orbit approaches are very similar. This is a consequence of the small spatial scales over which the ion orbits distribute the power. The key result of this study is that the computationally much less intensive ion orbit approximation can be used with confidence in monoblock shaping design studies, thus validating the approach used in Gunn et al (2017 Nucl. Fusion 57 046025).

A Time-Space Domain Information Fusion Method for Specific Emitter Identification Based on Dempster-Shafer Evidence Theory.

PubMed

Jiang, Wen; Cao, Ying; Yang, Lin; He, Zichang

2017-08-28

Specific emitter identification plays an important role in contemporary military affairs. However, most of the existing specific emitter identification methods haven't taken into account the processing of uncertain information. Therefore, this paper proposes a time-space domain information fusion method based on Dempster-Shafer evidence theory, which has the ability to deal with uncertain information in the process of specific emitter identification. In this paper, radars will generate a group of evidence respectively based on the information they obtained, and our main task is to fuse the multiple groups of evidence to get a reasonable result. Within the framework of recursive centralized fusion model, the proposed method incorporates a correlation coefficient, which measures the relevance between evidence and a quantum mechanical approach, which is based on the parameters of radar itself. The simulation results of an illustrative example demonstrate that the proposed method can effectively deal with uncertain information and get a reasonable recognition result.

Evaluation between residual stresses obtained by neutron diffraction and simulation for dual phase steel welded by laser process

NASA Astrophysics Data System (ADS)

Kouadri-Henni, Afia; Malard, Benoit

2018-05-01

This study aimed at characterizing the residual stresses (RS) distribution of a Dual Phase Steel (DP600) undergoing a Laser Beam Welding (LBW) with two different laser parameters. The RS in the ferritic phase have been experimentally determined by the use of the neutrons diffraction technique. The results confirmed a gradient of RS among different zones both on the top and below surfaces but also through the thickness of the fusion zone. Low compressive stresses were observed in the Base Metal (BM) close to the Heat Affected Zone (HAZ) whereas high tensile stresses were observed in the Fusion Zone (FZ). Numerical results showed a difference in the RS distribution depending on the model used. In the end, it appears that the high temperature gradient, specific to the laser beam, is the main factor governing the RS. Our results suggest as well that the approach regarding the RS should consider not only the temperature but also process parameters. When comparing simulation results with experimental data, the values converge well in some zones, in particular the FZ and the others less.

Acoustically Driven Magnetized Target Fusion At General Fusion: An Overview

NASA Astrophysics Data System (ADS)

O'Shea, Peter; Laberge, M.; Donaldson, M.; Delage, M.; the Fusion Team, General

2016-10-01

Magnetized Target Fusion (MTF) involves compressing an initial magnetically confined plasma of about 1e23 m-3, 100eV, 7 Tesla, 20 cm radius, >100 μsec life with a 1000x volume compression in 100 microseconds. If near adiabatic compression is achieved, the final plasma of 1e26 m-3, 10keV, 700 Tesla, 2 cm radius, confined for 10 μsec would produce interesting fusion energy gain. General Fusion (GF) is developing an acoustic compression system using pneumatic pistons focusing a shock wave on the CT plasma in the center of a 3 m diameter sphere filled with liquid lead-lithium. Low cost driver, straightforward heat extraction, good tritium breeding ratio and excellent neutron protection could lead to a practical power plant. GF (65 employees) has an active plasma R&D program including both full scale and reduced scale plasma experiments and simulation of both. Although acoustic driven compression of full scale plasmas is the end goal, present compression studies use reduced scale plasmas and chemically accelerated Aluminum liners. We will review results from our plasma target development, motivate and review the results of dynamic compression field tests and briefly describe the work to date on the acoustic driver front.

Effect of retransmission and retrodiction on estimation and fusion in long-haul sensor networks

DOE PAGES

Liu, Qiang; Wang, Xin; Rao, Nageswara S. V.; ...

2016-01-01

In a long-haul sensor network, sensors are remotely deployed over a large geographical area to perform certain tasks, such as target tracking. In this work, we study the scenario where sensors take measurements of one or more dynamic targets and send state estimates of the targets to a fusion center via satellite links. The severe loss and delay inherent over the satellite channels reduce the number of estimates successfully arriving at the fusion center, thereby limiting the potential fusion gain and resulting in suboptimal accuracy performance of the fused estimates. In addition, the errors in target-sensor data association can alsomore » degrade the estimation performance. To mitigate the effect of imperfect communications on state estimation and fusion, we consider retransmission and retrodiction. The system adopts certain retransmission-based transport protocols so that lost messages can be recovered over time. Besides, retrodiction/smoothing techniques are applied so that the chances of incurring excess delay due to retransmission are greatly reduced. We analyze the extent to which retransmission and retrodiction can improve the performance of delay-sensitive target tracking tasks under variable communication loss and delay conditions. Lastly, simulation results of a ballistic target tracking application are shown in the end to demonstrate the validity of our analysis.« less

Multisensor fusion with non-optimal decision rules: the challenges of open world sensing

NASA Astrophysics Data System (ADS)

Minor, Christian; Johnson, Kevin

2014-05-01

In this work, simple, generic models of chemical sensing are used to simulate sensor array data and to illustrate the impact on overall system performance that specific design choices impart. The ability of multisensor systems to perform multianalyte detection (i.e., distinguish multiple targets) is explored by examining the distinction between fundamental design-related limitations stemming from mismatching of mixture composition to fused sensor measurement spaces, and limitations that arise from measurement uncertainty. Insight on the limits and potential of sensor fusion to robustly address detection tasks in realistic field conditions can be gained through an examination of a) the underlying geometry of both the composition space of sources one hopes to elucidate and the measurement space a fused sensor system is capable of generating, and b) the informational impact of uncertainty on both of these spaces. For instance, what is the potential impact on sensor fusion in an open world scenario where unknown interferants may contaminate target signals? Under complex and dynamic backgrounds, decision rules may implicitly become non-optimal and adding sensors may increase the amount of conflicting information observed. This suggests that the manner in which a decision rule handles sensor conflict can be critical in leveraging sensor fusion for effective open world sensing, and becomes exponentially more important as more sensors are added. Results and design considerations for handling conflicting evidence in Bayes and Dempster-Shafer fusion frameworks are presented. Bayesian decision theory is used to provide an upper limit on detector performance of simulated sensor systems.

Effects of Preoperative Simulation on Minimally Invasive Hybrid Lumbar Interbody Fusion.

PubMed

Rieger, Bernhard; Jiang, Hongzhen; Reinshagen, Clemens; Molcanyi, Marek; Zivcak, Jozef; Grönemeyer, Dietrich; Bosche, Bert; Schackert, Gabriele; Ruess, Daniel

2017-10-01

The main focus of this study was to evaluate how preoperative simulation affects the surgical work flow, radiation exposure, and outcome of minimally invasive hybrid lumbar interbody fusion (MIS-HLIF). A total of 132 patients who underwent single-level MIS-HLIF were enrolled in a cohort study design. Dose area product was analyzed in addition to surgical data. Once preoperative simulation was established, 66 cases (SIM cohort) were compared with 66 patients who had previously undergone MIS-HLIF without preoperative simulation (NO-SIM cohort). Dose area product was reduced considerably in the SIM cohort (320 cGy·cm 2 NO-SIM cohort: 470 cGy·cm 2 ; P < 0.01). Surgical time was shorter for the SIM cohort (155 minutes; NO-SIM cohort, 182 minutes; P < 0.05). SIM cohort had a better outcome in Numeric Rating Scale back at 6 months follow-up compared with the NO-SIM cohort (P < 0.05). Preoperative simulation reduced radiation exposure and resulted in less back pain at the 6 months follow-up time point. Preoperative simulation provided guidance in determining the correct cage height. Outcome controls enabled the surgeon to improve the procedure and the software algorithm. Copyright © 2017 Elsevier Inc. All rights reserved.

Largescale Long-term particle Simulations of Runaway electrons in Tokamaks

NASA Astrophysics Data System (ADS)

Liu, Jian; Qin, Hong; Wang, Yulei

2016-10-01

To understand runaway dynamical behavior is crucial to assess the safety of tokamaks. Though many important analytical and numerical results have been achieved, the overall dynamic behaviors of runaway electrons in a realistic tokamak configuration is still rather vague. In this work, the secular full-orbit simulations of runaway electrons are carried out based on a relativistic volume-preserving algorithm. Detailed phase-space behaviors of runaway electrons are investigated in different timescales spanning 11 orders. A detailed analysis of the collisionless neoclassical scattering is provided when considering the coupling between the rotation of momentum vector and the background field. In large timescale, the initial condition of runaway electrons in phase space globally influences the runaway distribution. It is discovered that parameters and field configuration of tokamaks can modify the runaway electron dynamics significantly. Simulations on 10 million cores of supercomputer using the APT code have been completed. A resolution of 107 in phase space is used, and simulations are performed for 1011 time steps. Largescale simulations show that in a realistic fusion reactor, the concern of runaway electrons is not as serious as previously thought. This research was supported by National Magnetic Connement Fusion Energy Research Project (2015GB111003, 2014GB124005), the National Natural Science Foundation of China (NSFC-11575185, 11575186) and the GeoAlgorithmic Plasma Simulator (GAPS) Project.

Fusion of raft-like lipid bilayers operated by a membranotropic domain of the HSV-type I glycoprotein gH occurs through a cholesterol-dependent mechanism.

PubMed

Vitiello, Giuseppe; Falanga, Annarita; Petruk, Ariel Alcides; Merlino, Antonello; Fragneto, Giovanna; Paduano, Luigi; Galdiero, Stefania; D'Errico, Gerardino

2015-04-21

A wealth of evidence indicates that lipid rafts are involved in the fusion of the viral lipid envelope with the target cell membrane. However, the interplay between these sterol- and sphingolipid-enriched ordered domains and viral fusion glycoproteins has not yet been clarified. In this work we investigate the molecular mechanism by which a membranotropic fragment of the glycoprotein gH of the Herpes Simplex Virus (HSV) type I (gH625) drives fusion of lipid bilayers formed by palmitoyl oleoyl phosphatidylcholine (POPC)-sphingomyelin (SM)-cholesterol (CHOL) (1 : 1 : 1 wt/wt/wt), focusing on the role played by each component. The comparative analysis of the liposome fusion assays, Dynamic Light Scattering (DLS), spectrofluorimetry, Neutron Reflectivity (NR) and Electron Spin Resonance (ESR) experiments, and Molecular Dynamics (MD) simulations shows that CHOL is fundamental for liposome fusion to occur. In detail, CHOL stabilizes the gH625-bilayer association by specific interactions with the peptide Trp residue. The interaction with gH625 causes an increased order of the lipid acyl chains, whose local rotational motion is significantly hampered. SM plays only a minor role in the process, favoring the propagation of lipid perturbation to the bilayer inner core. The stiffening of the peptide-interacting bilayer leaflet results in an asymmetric perturbation of the membrane, which is locally destabilized thus favoring fusion events. Our results show that viral fusion glycoproteins are optimally suited to exert a high fusogenic activity on lipid rafts and support the relevance of cholesterol as a key player of membrane-related processes.

Integrated simulation of magnetic-field-assist fast ignition laser fusion

NASA Astrophysics Data System (ADS)

Johzaki, T.; Nagatomo, H.; Sunahara, A.; Sentoku, Y.; Sakagami, H.; Hata, M.; Taguchi, T.; Mima, K.; Kai, Y.; Ajimi, D.; Isoda, T.; Endo, T.; Yogo, A.; Arikawa, Y.; Fujioka, S.; Shiraga, H.; Azechi, H.

2017-01-01

To enhance the core heating efficiency in fast ignition laser fusion, the concept of relativistic electron beam guiding by external magnetic fields was evaluated by integrated simulations for FIREX class targets. For the cone-attached shell target case, the core heating performance deteriorates by applying magnetic fields since the core is considerably deformed and most of the fast electrons are reflected due to the magnetic mirror formed through the implosion. On the other hand, in the case of a cone-attached solid ball target, the implosion is more stable under the kilo-tesla-class magnetic field. In addition, feasible magnetic field configuration is formed through the implosion. As a result, the core heating efficiency doubles by magnetic guiding. The dependence of core heating properties on the heating pulse shot timing was also investigated for the solid ball target.

LINE: a code which simulates spectral line shapes for fusion reaction products generated by various speed distributions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Slaughter, D.

1985-03-01

A computer code is described which estimates the energy spectrum or ''line-shape'' for the charged particles and ..gamma..-rays produced by the fusion of low-z ions in a hot plasma. The simulation has several ''built-in'' ion velocity distributions characteristic of heated plasmas and it also accepts arbitrary speed and angular distributions although they must all be symmetric about the z-axis. An energy spectrum of one of the reaction products (ion, neutron, or ..gamma..-ray) is calculated at one angle with respect to the symmetry axis. The results are shown in tabular form, they are plotted graphically, and the moments of the spectrummore » to order ten are calculated both with respect to the origin and with respect to the mean.« less

Two-plasmon decay mitigation in direct-drive inertial-confinement-fusion experiments using multilayer targets

DOE PAGES

Follett, R. K.; Delettrez, J. A.; Edgell, D. H.; ...

2016-04-15

Multilayer direct-drive inertial-confinement-fusion (ICF) targets are shown to significantly reduce two-plasmon-decay (TPD) driven hot-electron production while maintaining high hydrodynamic efficiency. Implosion experiments on the OMEGA Laser used targets with silicon layered between an inner beryllium and outer silicon-doped plastic ablator. A factor of five reduction in hot-electron generation (> 50 keV) was observed in the multilayer targets relative to pure CH targets. Three-dimensional simulations of the TPD driven hot-electron production using a laser-plasma interaction code (LPSE) that includes nonlinear and kinetic effects show excellent agreement with the measurements. As a result, the simulations suggest that the reduction in hot-electron productionmore » observed in the multilayer targets is primarily due to increased electron-ion collisional damping.« less

Multi-focus image fusion and robust encryption algorithm based on compressive sensing

NASA Astrophysics Data System (ADS)

Xiao, Di; Wang, Lan; Xiang, Tao; Wang, Yong

2017-06-01

Multi-focus image fusion schemes have been studied in recent years. However, little work has been done in multi-focus image transmission security. This paper proposes a scheme that can reduce data transmission volume and resist various attacks. First, multi-focus image fusion based on wavelet decomposition can generate complete scene images and optimize the perception of the human eye. The fused images are sparsely represented with DCT and sampled with structurally random matrix (SRM), which reduces the data volume and realizes the initial encryption. Then the obtained measurements are further encrypted to resist noise and crop attack through combining permutation and diffusion stages. At the receiver, the cipher images can be jointly decrypted and reconstructed. Simulation results demonstrate the security and robustness of the proposed scheme.

Combined Effects of Simulated Microgravity and Radiation Exposure on Osteoclast Cell Fusion.

PubMed

Shanmugarajan, Srinivasan; Zhang, Ye; Moreno-Villanueva, Maria; Clanton, Ryan; Rohde, Larry H; Ramesh, Govindarajan T; Sibonga, Jean D; Wu, Honglu

2017-11-18

The loss of bone mass and alteration in bone physiology during space flight are one of the major health risks for astronauts. Although the lack of weight bearing in microgravity is considered a risk factor for bone loss and possible osteoporosis, organisms living in space are also exposed to cosmic radiation and other environmental stress factors. As such, it is still unclear as to whether and by how much radiation exposure contributes to bone loss during space travel, and whether the effects of microgravity and radiation exposure are additive or synergistic. Bone is continuously renewed through the resorption of old bone by osteoclast cells and the formation of new bone by osteoblast cells. In this study, we investigated the combined effects of microgravity and radiation by evaluating the maturation of a hematopoietic cell line to mature osteoclasts. RAW 264.7 monocyte/macrophage cells were cultured in rotating wall vessels that simulate microgravity on the ground. Cells under static 1g or simulated microgravity were exposed to γ rays of varying doses, and then cultured in receptor activator of nuclear factor-κB ligand (RANKL) for the formation of osteoclast giant multinucleated cells (GMCs) and for gene expression analysis. Results of the study showed that radiation alone at doses as low as 0.1 Gy may stimulate osteoclast cell fusion as assessed by GMCs and the expression of signature genes such as tartrate resistant acid phosphatase ( Trap ) and dendritic cell-specific transmembrane protein ( Dcstamp ). However, osteoclast cell fusion decreased for doses greater than 0.5 Gy. In comparison to radiation exposure, simulated microgravity induced higher levels of cell fusion, and the effects of these two environmental factors appeared additive. Interestingly, the microgravity effect on osteoclast stimulatory transmembrane protein ( Ocstamp ) and Dcstamp expressions was significantly higher than the radiation effect, suggesting that radiation may not increase the synthesis of adhesion molecules as much as microgravity.

A hybrid model for coupling kinetic corrections of fusion reactivity to hydrodynamic implosion simulations

NASA Astrophysics Data System (ADS)

Tang, Xian-Zhu; McDevitt, C. J.; Guo, Zehua; Berk, H. L.

2014-03-01

Inertial confinement fusion requires an imploded target in which a central hot spot is surrounded by a cold and dense pusher. The hot spot/pusher interface can take complicated shape in three dimensions due to hydrodynamic mix. It is also a transition region where the Knudsen and inverse Knudsen layer effect can significantly modify the fusion reactivity in comparison with the commonly used value evaluated with background Maxwellians. Here, we describe a hybrid model that couples the kinetic correction of fusion reactivity to global hydrodynamic implosion simulations. The key ingredient is a non-perturbative treatment of the tail ions in the interface region where the Gamow ion Knudsen number approaches or surpasses order unity. The accuracy of the coupling scheme is controlled by the precise criteria for matching the non-perturbative kinetic model to perturbative solutions in both configuration space and velocity space.

A Motion Tracking and Sensor Fusion Module for Medical Simulation.

PubMed

Shen, Yunhe; Wu, Fan; Tseng, Kuo-Shih; Ye, Ding; Raymond, John; Konety, Badrinath; Sweet, Robert

2016-01-01

Here we introduce a motion tracking or navigation module for medical simulation systems. Our main contribution is a sensor fusion method for proximity or distance sensors integrated with inertial measurement unit (IMU). Since IMU rotation tracking has been widely studied, we focus on the position or trajectory tracking of the instrument moving freely within a given boundary. In our experiments, we have found that this module reliably tracks instrument motion.

Design of two-DMD based zoom MW and LW dual-band IRSP using pixel fusion

NASA Astrophysics Data System (ADS)

Pan, Yue; Xu, Xiping; Qiao, Yang

2018-06-01

In order to test the anti-jamming ability of mid-wave infrared (MWIR) and long-wave infrared (LWIR) dual-band imaging system, a zoom mid-wave (MW) and long-wave (LW) dual-band infrared scene projector (IRSP) based on two-digital micro-mirror device (DMD) was designed by using a projection method of pixel fusion. Two illumination systems, which illuminate the two DMDs directly with Kohler telecentric beam respectively, were combined with projection system by a spatial layout way. The distances of projection entrance pupil and illumination exit pupil were also analyzed separately. MWIR and LWIR virtual scenes were generated respectively by two DMDs and fused by a dichroic beam combiner (DBC), resulting in two radiation distributions in projected image. The optical performance of each component was evaluated by ray tracing simulations. Apparent temperature and image contrast were demonstrated by imaging experiments. On the basis of test and simulation results, the aberrations of optical system were well corrected, and the quality of projected image meets test requirements.

Extreme Scale Plasma Turbulence Simulations on Top Supercomputers Worldwide

DOE PAGES

Tang, William; Wang, Bei; Ethier, Stephane; ...

2016-11-01

The goal of the extreme scale plasma turbulence studies described in this paper is to expedite the delivery of reliable predictions on confinement physics in large magnetic fusion systems by using world-class supercomputers to carry out simulations with unprecedented resolution and temporal duration. This has involved architecture-dependent optimizations of performance scaling and addressing code portability and energy issues, with the metrics for multi-platform comparisons being 'time-to-solution' and 'energy-to-solution'. Realistic results addressing how confinement losses caused by plasma turbulence scale from present-day devices to the much larger $25 billion international ITER fusion facility have been enabled by innovative advances in themore » GTC-P code including (i) implementation of one-sided communication from MPI 3.0 standard; (ii) creative optimization techniques on Xeon Phi processors; and (iii) development of a novel performance model for the key kernels of the PIC code. Our results show that modeling data movement is sufficient to predict performance on modern supercomputer platforms.« less

A methodology for generating normal and pathological brain perfusion SPECT images for evaluation of MRI/SPECT fusion methods: application in epilepsy

NASA Astrophysics Data System (ADS)

Grova, C.; Jannin, P.; Biraben, A.; Buvat, I.; Benali, H.; Bernard, A. M.; Scarabin, J. M.; Gibaud, B.

2003-12-01

Quantitative evaluation of brain MRI/SPECT fusion methods for normal and in particular pathological datasets is difficult, due to the frequent lack of relevant ground truth. We propose a methodology to generate MRI and SPECT datasets dedicated to the evaluation of MRI/SPECT fusion methods and illustrate the method when dealing with ictal SPECT. The method consists in generating normal or pathological SPECT data perfectly aligned with a high-resolution 3D T1-weighted MRI using realistic Monte Carlo simulations that closely reproduce the response of a SPECT imaging system. Anatomical input data for the SPECT simulations are obtained from this 3D T1-weighted MRI, while functional input data result from an inter-individual analysis of anatomically standardized SPECT data. The method makes it possible to control the 'brain perfusion' function by proposing a theoretical model of brain perfusion from measurements performed on real SPECT images. Our method provides an absolute gold standard for assessing MRI/SPECT registration method accuracy since, by construction, the SPECT data are perfectly registered with the MRI data. The proposed methodology has been applied to create a theoretical model of normal brain perfusion and ictal brain perfusion characteristic of mesial temporal lobe epilepsy. To approach realistic and unbiased perfusion models, real SPECT data were corrected for uniform attenuation, scatter and partial volume effect. An anatomic standardization was used to account for anatomic variability between subjects. Realistic simulations of normal and ictal SPECT deduced from these perfusion models are presented. The comparison of real and simulated SPECT images showed relative differences in regional activity concentration of less than 20% in most anatomical structures, for both normal and ictal data, suggesting realistic models of perfusion distributions for evaluation purposes. Inter-hemispheric asymmetry coefficients measured on simulated data were found within the range of asymmetry coefficients measured on corresponding real data. The features of the proposed approach are compared with those of other methods previously described to obtain datasets appropriate for the assessment of fusion methods.

Magnetic Compression Experiment at General Fusion with Simulation Results

NASA Astrophysics Data System (ADS)

Dunlea, Carl; Khalzov, Ivan; Hirose, Akira; Xiao, Chijin; Fusion Team, General

2017-10-01

The magnetic compression experiment at GF was a repetitive non-destructive test to study plasma physics applicable to Magnetic Target Fusion compression. A spheromak compact torus (CT) is formed with a co-axial gun into a containment region with an hour-glass shaped inner flux conserver, and an insulating outer wall. External coil currents keep the CT off the outer wall (levitation) and then rapidly compress it inwards. The optimal external coil configuration greatly improved both the levitated CT lifetime and the rate of shots with good compressional flux conservation. As confirmed by spectrometer data, the improved levitation field profile reduced plasma impurity levels by suppressing the interaction between plasma and the insulating outer wall during the formation process. We developed an energy and toroidal flux conserving finite element axisymmetric MHD code to study CT formation and compression. The Braginskii MHD equations with anisotropic heat conduction were implemented. To simulate plasma / insulating wall interaction, we couple the vacuum field solution in the insulating region to the full MHD solution in the remainder of the domain. We see good agreement between simulation and experiment results. Partly funded by NSERC and MITACS Accelerate.

Control of Warm Compression Stations Using Model Predictive Control: Simulation and Experimental Results

NASA Astrophysics Data System (ADS)

Bonne, F.; Alamir, M.; Bonnay, P.

2017-02-01

This paper deals with multivariable constrained model predictive control for Warm Compression Stations (WCS). WCSs are subject to numerous constraints (limits on pressures, actuators) that need to be satisfied using appropriate algorithms. The strategy is to replace all the PID loops controlling the WCS with an optimally designed model-based multivariable loop. This new strategy leads to high stability and fast disturbance rejection such as those induced by a turbine or a compressor stop, a key-aspect in the case of large scale cryogenic refrigeration. The proposed control scheme can be used to achieve precise control of pressures in normal operation or to avoid reaching stopping criteria (such as excessive pressures) under high disturbances (such as a pulsed heat load expected to take place in future fusion reactors, expected in the cryogenic cooling systems of the International Thermonuclear Experimental Reactor ITER or the Japan Torus-60 Super Advanced fusion experiment JT-60SA). The paper details the simulator used to validate this new control scheme and the associated simulation results on the SBTs WCS. This work is partially supported through the French National Research Agency (ANR), task agreement ANR-13-SEED-0005.

Effect of equation of state on laser imprinting by comparing diamond and polystyrene foils

NASA Astrophysics Data System (ADS)

Kato, H.; Shigemori, K.; Nagatomo, H.; Nakai, M.; Sakaiya, T.; Ueda, T.; Terasaki, H.; Hironaka, Y.; Shimizu, K.; Azechi, H.

2018-03-01

We present herein a comprehensive study of how the equation of state affects laser imprinting by nonuniform laser irradiation of an inertial fusion target. It has been suggested that a stiffer and denser material would reduce laser imprinting based on the equation of motion with pressure perturbation. We examine the detailed temporal evolution of the imprint amplitude by using the two-dimensional radiation hydrodynamic simulation PINOCO-2D for diamond, which is a candidate stiff-ablator material for inertial fusion targets. The simulated laser imprinting amplitude is compared with experimental measurements of areal-density perturbations obtained by using face-on x-ray backlighting for diamond and polystyrene (PS) (the latter as a reference). The experimental results are well reproduced by the results of the PINOCO-2D simulation, which indicates that the imprinting amplitude due to nonuniform irradiation (average intensity, 4.0 × 1012 to 5.0 × 1013) differs by a factor of two to three between diamond and PS. The difference in laser imprinting is mainly related to the material density and compressibility. These parameters are key factors that determine the laser imprinting amplitude.

Sacroiliac Joint Fusion Minimally Affects Adjacent Lumbar Segment Motion: A Finite Element Study.

PubMed

Lindsey, Derek P; Kiapour, Ali; Yerby, Scott A; Goel, Vijay K

2015-01-01

Adjacent segment disease is a recognized consequence of fusion in the spinal column. Fusion of the sacroiliac joint is an effective method of pain reduction. Although effective, the consequences of sacroiliac joint fusion and the potential for adjacent segment disease for the adjacent lumbar spinal levels is unknown. The objective of this study was to quantify the change in range of motion of the sacroiliac joint and the adjacent lumbar spinal motion segments due to sacroiliac joint fusion and compare these changes to previous literature to assess the potential for adjacent segment disease in the lumbar spine. An experimentally validated finite element model of the lumbar spine and pelvis was used to simulate a fusion of the sacroiliac joint using three laterally placed triangular implants (iFuse Implant System, SI-BONE, Inc., San Jose, CA). The range of motion of the sacroiliac joint and the adjacent lumbar spinal motion segments were calculated using a hybrid loading protocol and compared with the intact range of motion in flexion, extension, lateral bending, and axial rotation. The range of motions of the treated sacroiliac joints were reduced in flexion, extension, lateral bending, and axial rotation, by 56.6%, 59.5%, 27.8%, and 53.3%, respectively when compared with the intact condition. The stiffening of the sacroiliac joint resulted in increases at the adjacent lumbar motion segment (L5-S1) for flexion, extension, lateral bending, and axial rotation, of 3.0%, 3.7%, 1.1%, and 4.6%, respectively. Fusion of the sacroiliac joint resulted in substantial (> 50%) reductions in flexion, extension, and axial rotation of the sacroiliac joint with minimal (< 5%) increases in range of motion in the lumbar spine. Although the predicted increases in lumbar range of motion are minimal after sacroiliac joint fusion, the long-term clinical results remain to be investigated.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Arnold H. Kritz

PTRANSP, which is the predictive version of the TRANSP code, was developed in a collaborative effort involving the Princeton Plasma Physics Laboratory, General Atomics Corporation, Lawrence Livermore National Laboratory, and Lehigh University. The PTRANSP/TRANSP suite of codes is the premier integrated tokamak modeling software in the United States. A production service for PTRANSP/TRANSP simulations is maintained at the Princeton Plasma Physics Laboratory; the server has a simple command line client interface and is subscribed to by about 100 researchers from tokamak projects in the US, Europe, and Asia. This service produced nearly 13000 PTRANSP/TRANSP simulations in the four year periodmore » FY 2005 through FY 2008. Major archives of TRANSP results are maintained at PPPL, MIT, General Atomics, and JET. Recent utilization, counting experimental analysis simulations as well as predictive simulations, more than doubled from slightly over 2000 simulations per year in FY 2005 and FY 2006 to over 4300 simulations per year in FY 2007 and FY 2008. PTRANSP predictive simulations applied to ITER increased eight fold from 30 simulations per year in FY 2005 and FY 2006 to 240 simulations per year in FY 2007 and FY 2008, accounting for more than half of combined PTRANSP/TRANSP service CPU resource utilization in FY 2008. PTRANSP studies focused on ITER played a key role in journal articles. Examples of validation studies carried out for momentum transport in PTRANSP simulations were presented at the 2008 IAEA conference. The increase in number of PTRANSP simulations has continued (more than 7000 TRANSP/PTRANSP simulations in 2010) and results of PTRANSP simulations appear in conference proceedings, for example the 2010 IAEA conference, and in peer reviewed papers. PTRANSP provides a bridge to the Fusion Simulation Program (FSP) and to the future of integrated modeling. Through years of widespread usage, each of the many parts of the PTRANSP suite of codes has been thoroughly validated against experimental data and benchmarked against other codes. At the same time, architectural modernizations are improving the modularity of the PTRANSP code base. The NUBEAM neutral beam and fusion products fast ion model, the Plasma State data repository (developed originally in the SWIM SciDAC project and adapted for use in PTRANSP), and other components are already shared with the SWIM, FACETS, and CPES SciDAC FSP prototype projects. Thus, the PTRANSP code is already serving as a bridge between our present integrated modeling capability and future capability. As the Fusion Simulation Program builds toward the facility currently available in the PTRANSP suite of codes, early versions of the FSP core plasma model will need to be benchmarked against the PTRANSP simulations. This will be necessary to build user confidence in FSP, but this benchmarking can only be done if PTRANSP itself is maintained and developed.« less

Human visual system consistent quality assessment for remote sensing image fusion

NASA Astrophysics Data System (ADS)

Liu, Jun; Huang, Junyi; Liu, Shuguang; Li, Huali; Zhou, Qiming; Liu, Junchen

2015-07-01

Quality assessment for image fusion is essential for remote sensing application. Generally used indices require a high spatial resolution multispectral (MS) image for reference, which is not always readily available. Meanwhile, the fusion quality assessments using these indices may not be consistent with the Human Visual System (HVS). As an attempt to overcome this requirement and inconsistency, this paper proposes an HVS-consistent image fusion quality assessment index at the highest resolution without a reference MS image using Gaussian Scale Space (GSS) technology that could simulate the HVS. The spatial details and spectral information of original and fused images are first separated in GSS, and the qualities are evaluated using the proposed spatial and spectral quality index respectively. The overall quality is determined without a reference MS image by a combination of the proposed two indices. Experimental results on various remote sensing images indicate that the proposed index is more consistent with HVS evaluation compared with other widely used indices that may or may not require reference images.

Simulation of High-Beta Plasma Confinement

NASA Astrophysics Data System (ADS)

Font, Gabriel; Welch, Dale; Mitchell, Robert; McGuire, Thomas

2017-10-01

The Lockheed Martin Compact Fusion Reactor concept utilizes magnetic cusps to confine the plasma. In order to minimize losses through the axial and ring cusps, the plasma is pushed to a high-beta state. Simulations were made of the plasma and magnetic field system in an effort to quantify particle confinement times and plasma behavior characteristics. Computations are carried out with LSP using implicit PIC methods. Simulations of different sub-scale geometries at high-Beta fusion conditions are used to determine particle loss scaling with reactor size, plasma conditions, and gyro radii. ©2017 Lockheed Martin Corporation. All Rights Reserved.

Regular Deployment of Wireless Sensors to Achieve Connectivity and Information Coverage

PubMed Central

Cheng, Wei; Li, Yong; Jiang, Yi; Yin, Xipeng

2016-01-01

Coverage and connectivity are two of the most critical research subjects in WSNs, while regular deterministic deployment is an important deployment strategy and results in some pattern-based lattice WSNs. Some studies of optimal regular deployment for generic values of rc/rs were shown recently. However, most of these deployments are subject to a disk sensing model, and cannot take advantage of data fusion. Meanwhile some other studies adapt detection techniques and data fusion to sensing coverage to enhance the deployment scheme. In this paper, we provide some results on optimal regular deployment patterns to achieve information coverage and connectivity as a variety of rc/rs, which are all based on data fusion by sensor collaboration, and propose a novel data fusion strategy for deployment patterns. At first the relation between variety of rc/rs and density of sensors needed to achieve information coverage and connectivity is derived in closed form for regular pattern-based lattice WSNs. Then a dual triangular pattern deployment based on our novel data fusion strategy is proposed, which can utilize collaborative data fusion more efficiently. The strip-based deployment is also extended to a new pattern to achieve information coverage and connectivity, and its characteristics are deduced in closed form. Some discussions and simulations are given to show the efficiency of all deployment patterns, including previous patterns and the proposed patterns, to help developers make more impactful WSN deployment decisions. PMID:27529246

Evaluation of Effective Parameters on Quality of Magnetic Resonance Imaging-computed Tomography Image Fusion in Head and Neck Tumors for Application in Treatment Planning.

PubMed

Shirvani, Atefeh; Jabbari, Keyvan; Amouheidari, Alireza

2017-01-01

In radiation therapy, computed tomography (CT) simulation is used for treatment planning to define the location of tumor. Magnetic resonance imaging (MRI)-CT image fusion leads to more efficient tumor contouring. This work tried to identify the practical issues for the combination of CT and MRI images in real clinical cases. The effect of various factors is evaluated on image fusion quality. In this study, the data of thirty patients with brain tumors were used for image fusion. The effect of several parameters on possibility and quality of image fusion was evaluated. These parameters include angles of the patient's head on the bed, slices thickness, slice gap, and height of the patient's head. According to the results, the first dominating factor on quality of image fusion was the difference slice gap between CT and MRI images (cor = 0.86, P < 0.005) and second factor was the angle between CT and MRI slice in the sagittal plane (cor = 0.75, P < 0.005). In 20% of patients, this angle was more than 28° and image fusion was not efficient. In 17% of patients, difference slice gap in CT and MRI was >4 cm and image fusion quality was <25%. The most important problem in image fusion is that MRI images are taken without regard to their use in treatment planning. In general, parameters related to the patient position during MRI imaging should be chosen to be consistent with CT images of the patient in terms of location and angle.

Application and evaluation of ISVR method in QuickBird image fusion

NASA Astrophysics Data System (ADS)

Cheng, Bo; Song, Xiaolu

2014-05-01

QuickBird satellite images are widely used in many fields, and applications have put forward high requirements for the integration of the spatial information and spectral information of the imagery. A fusion method for high resolution remote sensing images based on ISVR is identified in this study. The core principle of ISVS is taking the advantage of radicalization targeting to remove the effect of different gain and error of satellites' sensors. Transformed from DN to radiance, the multi-spectral image's energy is used to simulate the panchromatic band. The linear regression analysis is carried through the simulation process to find a new synthetically panchromatic image, which is highly linearly correlated to the original panchromatic image. In order to evaluate, test and compare the algorithm results, this paper used ISVR and other two different fusion methods to give a comparative study of the spatial information and spectral information, taking the average gradient and the correlation coefficient as an indicator. Experiments showed that this method could significantly improve the quality of fused image, especially in preserving spectral information, to maximize the spectral information of original multispectral images, while maintaining abundant spatial information.

Driver fatigue detection through multiple entropy fusion analysis in an EEG-based system

PubMed Central

Min, Jianliang; Wang, Ping

2017-01-01

Driver fatigue is an important contributor to road accidents, and fatigue detection has major implications for transportation safety. The aim of this research is to analyze the multiple entropy fusion method and evaluate several channel regions to effectively detect a driver's fatigue state based on electroencephalogram (EEG) records. First, we fused multiple entropies, i.e., spectral entropy, approximate entropy, sample entropy and fuzzy entropy, as features compared with autoregressive (AR) modeling by four classifiers. Second, we captured four significant channel regions according to weight-based electrodes via a simplified channel selection method. Finally, the evaluation model for detecting driver fatigue was established with four classifiers based on the EEG data from four channel regions. Twelve healthy subjects performed continuous simulated driving for 1–2 hours with EEG monitoring on a static simulator. The leave-one-out cross-validation approach obtained an accuracy of 98.3%, a sensitivity of 98.3% and a specificity of 98.2%. The experimental results verified the effectiveness of the proposed method, indicating that the multiple entropy fusion features are significant factors for inferring the fatigue state of a driver. PMID:29220351

Enhancing Understanding of Magnetized High Energy Density Plasmas from Solid Liner Implosions Using Fluid Modeling with Kinetic Closures

NASA Astrophysics Data System (ADS)

Masti, Robert; Srinivasan, Bhuvana; King, Jacob; Stoltz, Peter; Hansen, David; Held, Eric

2017-10-01

Recent results from experiments and simulations of magnetically driven pulsed power liners have explored the role of early-time electrothermal instability in the evolution of the MRT (magneto-Rayleigh-Taylor) instability. Understanding the development of these instabilities can lead to potential stabilization mechanisms; thereby providing a significant role in the success of fusion concepts such as MagLIF (Magnetized Liner Inertial Fusion). For MagLIF the MRT instability is the most detrimental instability toward achieving fusion energy production. Experiments of high-energy density plasmas from wire-array implosions have shown the requirement for more advanced physics modeling than that of ideal magnetohydrodynamics. The overall focus of this project is on using a multi-fluid extended-MHD model with kinetic closures for thermal conductivity, resistivity, and viscosity. The extended-MHD model has been updated to include the SESAME equation-of-state tables and numerical benchmarks with this implementation will be presented. Simulations of MRT growth and evolution for MagLIF-relevant parameters will be presented using this extended-MHD model with the SESAME equation-of-state tables. This work is supported by the Department of Energy Office of Science under Grant Number DE-SC0016515.

Membrane insertion of fusion peptides from Ebola and Marburg viruses studied by replica-exchange molecular dynamics simulations.

PubMed

Olson, Mark A; Lee, Michael S; Yeh, In-Chul

2017-06-15

This work presents replica-exchange molecular dynamics simulations of inserting a 16-residue Ebola virus fusion peptide into a membrane bilayer. A computational approach is applied for modeling the peptide at the explicit all-atom level and the membrane-aqueous bilayer by a generalized Born continuum model with a smoothed switching function (GBSW). We provide an assessment of the model calculations in terms of three metrics: (1) the ability to reproduce the NMR structure of the peptide determined in the presence of SDS micelles and comparable structural data on other fusion peptides; (2) determination of the effects of the mutation Trp-8 to Ala and sequence discrimination of the homologous Marburg virus; and (3) calculation of potentials of mean force for estimating the partitioning free energy and their comparison to predictions from the Wimley-White interfacial hydrophobicity scale. We found the GBSW implicit membrane model to produce results of limited accuracy in conformational properties of the peptide when compared to the NMR structure, yet the model resolution is sufficient to determine the effect of sequence differentiation on peptide-membrane integration. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

Kernel-Based Sensor Fusion With Application to Audio-Visual Voice Activity Detection

NASA Astrophysics Data System (ADS)

Dov, David; Talmon, Ronen; Cohen, Israel

2016-12-01

In this paper, we address the problem of multiple view data fusion in the presence of noise and interferences. Recent studies have approached this problem using kernel methods, by relying particularly on a product of kernels constructed separately for each view. From a graph theory point of view, we analyze this fusion approach in a discrete setting. More specifically, based on a statistical model for the connectivity between data points, we propose an algorithm for the selection of the kernel bandwidth, a parameter, which, as we show, has important implications on the robustness of this fusion approach to interferences. Then, we consider the fusion of audio-visual speech signals measured by a single microphone and by a video camera pointed to the face of the speaker. Specifically, we address the task of voice activity detection, i.e., the detection of speech and non-speech segments, in the presence of structured interferences such as keyboard taps and office noise. We propose an algorithm for voice activity detection based on the audio-visual signal. Simulation results show that the proposed algorithm outperforms competing fusion and voice activity detection approaches. In addition, we demonstrate that a proper selection of the kernel bandwidth indeed leads to improved performance.

Atomistic Simulations of the pH Induced Functional Rearrangement of Influenza Hemagglutinin

NASA Astrophysics Data System (ADS)

Lin, Xingcheng; Noel, Jeffrey; Wang, Qinghua; Ma, Jianpeng; Onuchic, Jose

Influenza hemagglutinin (HA), a surface glycoprotein responsible for the entry and replication of flu viruses in their host cells, functions by starting a dramatic conformational rearrangement, which leads to a fusion of the viral and endosomal membranes. It has been claimed that a loop-to-coiled-coil transition of the B-loop domain of HA drives the HA-induced membrane fusion. On the lack of dynamical details, however, the microscopic picture for this proposed ``spring-loaded'' movement is missing. To elaborate on the transition of the B-loop, we performed a set of unbiased all-atom molecular dynamics simulations of the full B-loop structure with the CHARMM36 force field. The complete free-energy profile constructed from our simulations reveals a slow transition rate for the B-loop that is incompatible with a downhill process. Additionally, our simulations indicate two potential sources of kinetic traps in the structural switch of the B-loop: Desolvation barriers and non-native secondary structure formation. The slow timescale of the B-loop transition also confirms our previous discovery from simulations using a coarse-grained structure-based model, which identified two competitive pathways both with a slow B-loop transition for HA to guide the membrane fusion.

Simulating Operation of a Complex Sensor Network

NASA Technical Reports Server (NTRS)

Jennings, Esther; Clare, Loren; Woo, Simon

2008-01-01

Simulation Tool for ASCTA Microsensor Network Architecture (STAMiNA) ["ASCTA" denotes the Advanced Sensors Collaborative Technology Alliance.] is a computer program for evaluating conceptual sensor networks deployed over terrain to provide military situational awareness. This or a similar program is needed because of the complexity of interactions among such diverse phenomena as sensing and communication portions of a network, deployment of sensor nodes, effects of terrain, data-fusion algorithms, and threat characteristics. STAMiNA is built upon a commercial network-simulator engine, with extensions to include both sensing and communication models in a discrete-event simulation environment. Users can define (1) a mission environment, including terrain features; (2) objects to be sensed; (3) placements and modalities of sensors, abilities of sensors to sense objects of various types, and sensor false alarm rates; (4) trajectories of threatening objects; (5) means of dissemination and fusion of data; and (6) various network configurations. By use of STAMiNA, one can simulate detection of targets through sensing, dissemination of information by various wireless communication subsystems under various scenarios, and fusion of information, incorporating such metrics as target-detection probabilities, false-alarm rates, and communication loads, and capturing effects of terrain and threat.

Fusion silicide coatings for tantalum alloys.

NASA Technical Reports Server (NTRS)

Warnock, R. V.; Stetson, A. R.

1972-01-01

Calculation of the performance of fusion silicide coatings under simulated atmospheric reentry conditions to a maximum temperature of 1810 K (2800 F). Both recently developed and commercially available coatings are included. Data are presented on oxidation rate with and without intentional defecting, the influence of the coatings on the ductile-brittle bend transition temperature, and the mechanical properties. Coatings appear capable of affording protection for at least 100 simulated cycles to 2600 F and 63 cycles to 2800 F.

Welcome Back: Responses of Female Bonobos (Pan paniscus) to Fusions.

PubMed

Moscovice, Liza R; Deschner, Tobias; Hohmann, Gottfried

2015-01-01

In species with a high degree of fission-fusion social dynamics, fusions may trigger social conflict and thus provide an opportunity to identify sources of social tension and mechanisms related to its alleviation. We characterized behavioral and endocrine responses of captive female bonobos (Pan paniscus) to fusions within a zoo facility designed to simulate naturalistic fission-fusion social dynamics. We compared urinary cortisol levels and frequencies of aggression, grooming and socio-sexual interactions between female bonobos while in stable sub-groups and when one "joiner" was reunited with the "residents" of another sub-group. We hypothesized that fusions would trigger increases in aggression and cortisol levels among reunited joiners and resident females. We further predicted that females who face more uncertainty in their social interactions following fusions may use grooming and/or socio-sexual behavior to reduce social tension and aggression. The only aggression on reunion days occurred between reunited females, but frequencies of aggression remained low across non-reunion and reunion days, and there was no effect of fusions on cortisol levels. Fusions did not influence patterns of grooming, but there were increases in socio-sexual solicitations and socio-sexual interactions between joiners and resident females. Joiners who had been separated from residents for longer received the most solicitations, but were also more selective in their acceptance of solicitations and preferred to have socio-sexual interactions with higher-ranking residents. Our results suggest that socio-sexual interactions play a role in reintegrating female bonobos into social groups following fusions. In addition, females who receive a high number of solicitations are able to gain more control over their socio-sexual interactions and may use socio-sexual interactions for other purposes, such as to enhance their social standing.

Welcome Back: Responses of Female Bonobos (Pan paniscus) to Fusions

PubMed Central

Moscovice, Liza R.; Deschner, Tobias; Hohmann, Gottfried

2015-01-01

In species with a high degree of fission-fusion social dynamics, fusions may trigger social conflict and thus provide an opportunity to identify sources of social tension and mechanisms related to its alleviation. We characterized behavioral and endocrine responses of captive female bonobos (Pan paniscus) to fusions within a zoo facility designed to simulate naturalistic fission-fusion social dynamics. We compared urinary cortisol levels and frequencies of aggression, grooming and socio-sexual interactions between female bonobos while in stable sub-groups and when one “joiner” was reunited with the “residents” of another sub-group. We hypothesized that fusions would trigger increases in aggression and cortisol levels among reunited joiners and resident females. We further predicted that females who face more uncertainty in their social interactions following fusions may use grooming and/or socio-sexual behavior to reduce social tension and aggression. The only aggression on reunion days occurred between reunited females, but frequencies of aggression remained low across non-reunion and reunion days, and there was no effect of fusions on cortisol levels. Fusions did not influence patterns of grooming, but there were increases in socio-sexual solicitations and socio-sexual interactions between joiners and resident females. Joiners who had been separated from residents for longer received the most solicitations, but were also more selective in their acceptance of solicitations and preferred to have socio-sexual interactions with higher-ranking residents. Our results suggest that socio-sexual interactions play a role in reintegrating female bonobos into social groups following fusions. In addition, females who receive a high number of solicitations are able to gain more control over their socio-sexual interactions and may use socio-sexual interactions for other purposes, such as to enhance their social standing. PMID:25996476

Sensor Fusion of Gaussian Mixtures for Ballistic Target Tracking in the Re-Entry Phase

PubMed Central

Lu, Kelin; Zhou, Rui

2016-01-01

A sensor fusion methodology for the Gaussian mixtures model is proposed for ballistic target tracking with unknown ballistic coefficients. To improve the estimation accuracy, a track-to-track fusion architecture is proposed to fuse tracks provided by the local interacting multiple model filters. During the fusion process, the duplicate information is removed by considering the first order redundant information between the local tracks. With extensive simulations, we show that the proposed algorithm improves the tracking accuracy in ballistic target tracking in the re-entry phase applications. PMID:27537883

Early Career. Harnessing nanotechnology for fusion plasma-material interface research in an in-situ particle-surface interaction facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Allain, Jean Paul

2014-08-08

This project consisted of fundamental and applied research of advanced in-situ particle-beam interactions with surfaces/interfaces to discover novel materials able to tolerate intense conditions at the plasma-material interface (PMI) in future fusion burning plasma devices. The project established a novel facility that is capable of not only characterizing new fusion nanomaterials but, more importantly probing and manipulating materials at the nanoscale while performing subsequent single-effect in-situ testing of their performance under simulated environments in fusion PMI.

Sensor Fusion of Gaussian Mixtures for Ballistic Target Tracking in the Re-Entry Phase.

PubMed

Lu, Kelin; Zhou, Rui

2016-08-15

A sensor fusion methodology for the Gaussian mixtures model is proposed for ballistic target tracking with unknown ballistic coefficients. To improve the estimation accuracy, a track-to-track fusion architecture is proposed to fuse tracks provided by the local interacting multiple model filters. During the fusion process, the duplicate information is removed by considering the first order redundant information between the local tracks. With extensive simulations, we show that the proposed algorithm improves the tracking accuracy in ballistic target tracking in the re-entry phase applications.

Importance of lifetime effects in breakup and suppression of complete fusion in reactions of weakly bound nuclei

NASA Astrophysics Data System (ADS)

Cook, K. J.; Simpson, E. C.; Luong, D. H.; Kalkal, Sunil; Dasgupta, M.; Hinde, D. J.

2016-06-01

Background: Complete fusion cross sections in collisions of light weakly bound nuclei and high-Z targets show suppression of complete fusion at above-barrier energies. This has been interpreted as resulting from the breakup of the weakly bound nucleus prior to reaching the fusion barrier, reducing the probability of complete charge capture. Below-barrier studies of reactions of 9Be have found that the breakup of 8Be formed by neutron stripping dominates over direct breakup and that transfer-triggered breakup may account for the observed suppression of complete fusion. Purpose: This paper investigates how the above conclusions are affected by lifetimes of the resonant states that are populated prior to breakup. If the mean life of a populated resonance (above the breakup threshold) is much longer than the fusion time scale, then its breakup (decay) cannot suppress complete fusion. For short-lived resonances, the situation is more complex. This work explicitly includes the mean life of the short-lived 2+ resonance in 8Be in classical dynamical model calculations to determine its effect on energy and angular correlations of the breakup fragments and on model predictions of suppression of cross sections for complete fusion at above-barrier energies. Method: Previously performed coincidence measurements of breakup fragments produced in reactions of 9Be with 144Sm, 168Er, 186W, 196Pt, 208Pb, and 209Bi at energies below the barrier have been reanalyzed using an improved efficiency determination of the BALiN detector array. Predictions of breakup observables and of complete and incomplete fusion at energies above the fusion barrier are then made using the classical dynamical simulation code platypus, modified to include the effect of lifetimes of resonant states. Results: The agreement of the breakup observables is much improved when lifetime effects are included explicitly. Sensitivity to subzeptosecond lifetime is observed. The predicted suppression of complete fusion owing to breakup is nearly independent of Z and has an average value of ˜9 % . This is below the experimentally determined fusion suppression, which is typically ˜30 % in these systems. Conclusions: Inclusion of resonance lifetimes is essential to correctly reproduce breakup observables. This results in a larger fraction of nuclei remaining intact at the fusion-barrier radius compared with calculations that do not explicitly include lifetime effects. The more realistic treatment of breakup followed in this work leads to the conclusion that the suppression of complete fusion cannot be fully explained by breakup prior to reaching the fusion barrier. Only one-third of the observed fusion suppression can be attributed to the competing process of breakup. Other mechanisms that can suppress complete fusion must therefore be investigated. One of the possible candidates is cluster transfer that produces the same heavy targetlike nuclei as those formed by incomplete fusion.

PET and MRI image fusion based on combination of 2-D Hilbert transform and IHS method.

PubMed

Haddadpour, Mozhdeh; Daneshvar, Sabalan; Seyedarabi, Hadi

2017-08-01

The process of medical image fusion is combining two or more medical images such as Magnetic Resonance Image (MRI) and Positron Emission Tomography (PET) and mapping them to a single image as fused image. So purpose of our study is assisting physicians to diagnose and treat the diseases in the least of the time. We used Magnetic Resonance Image (MRI) and Positron Emission Tomography (PET) as input images, so fused them based on combination of two dimensional Hilbert transform (2-D HT) and Intensity Hue Saturation (IHS) method. Evaluation metrics that we apply are Discrepancy (D k ) as an assessing spectral features and Average Gradient (AG k ) as an evaluating spatial features and also Overall Performance (O.P) to verify properly of the proposed method. In this paper we used three common evaluation metrics like Average Gradient (AG k ) and the lowest Discrepancy (D k ) and Overall Performance (O.P) to evaluate the performance of our method. Simulated and numerical results represent the desired performance of proposed method. Since that the main purpose of medical image fusion is preserving both spatial and spectral features of input images, so based on numerical results of evaluation metrics such as Average Gradient (AG k ), Discrepancy (D k ) and Overall Performance (O.P) and also desired simulated results, it can be concluded that our proposed method can preserve both spatial and spectral features of input images. Copyright © 2017 Chang Gung University. Published by Elsevier B.V. All rights reserved.

A fully non-linear multi-species Fokker–Planck–Landau collision operator for simulation of fusion plasma

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hager, Robert, E-mail: rhager@pppl.gov; Yoon, E.S., E-mail: yoone@rpi.edu; Ku, S., E-mail: sku@pppl.gov

2016-06-15

Fusion edge plasmas can be far from thermal equilibrium and require the use of a non-linear collision operator for accurate numerical simulations. In this article, the non-linear single-species Fokker–Planck–Landau collision operator developed by Yoon and Chang (2014) [9] is generalized to include multiple particle species. The finite volume discretization used in this work naturally yields exact conservation of mass, momentum, and energy. The implementation of this new non-linear Fokker–Planck–Landau operator in the gyrokinetic particle-in-cell codes XGC1 and XGCa is described and results of a verification study are discussed. Finally, the numerical techniques that make our non-linear collision operator viable onmore » high-performance computing systems are described, including specialized load balancing algorithms and nested OpenMP parallelization. The collision operator's good weak and strong scaling behavior are shown.« less

Integrated Prediction and Mitigation Methods of Materials Damage and Lifetime Assessment during Plasma Operation and Various Instabilities in Fusion Devices

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hassanein, Ahmed

2015-03-31

This report describes implementation of comprehensive and integrated models to evaluate plasma material interactions during normal and abnormal plasma operations. The models in full3D simulations represent state-of-the art worldwide development with numerous benchmarking of various tokamak devices and plasma simulators. In addition, significant number of experimental work has been performed in our center for materials under extreme environment (CMUXE) at Purdue to benchmark the effect of intense particle and heat fluxes on plasma-facing components. This represents one-year worth of work and resulted in more than 23 Journal Publications and numerous conferences presentations. The funding has helped several students to obtainmore » their M.Sc. and Ph.D. degrees and many of them are now faculty members in US and around the world teaching and conducting fusion research. Our work has also been recognized through many awards.« less

Tropical cloud buoyancy is the same in a world with or without ice

NASA Astrophysics Data System (ADS)

Seeley, Jacob T.; Romps, David M.

2016-04-01

When convective clouds grow above the melting line, where temperatures fall below 0°C, condensed water begins to freeze and water vapor is deposited. These processes release the latent heat of fusion, which warms cloud air, and many previous studies have suggested that this heating from fusion increases cloud buoyancy in the upper troposphere. Here we use numerical simulations of radiative-convective equilibrium with and without ice processes to argue that tropical cloud buoyancy is not systematically higher in a world with fusion than in a world without it. This insensitivity results from the fact that the environmental temperature profile encountered by developing tropical clouds is itself determined by convection. We also offer a simple explanation for the large reservoir of convective available potential energy in the tropical upper troposphere that does not invoke ice.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shi, Xin, E-mail: xinshih86029@gmail.com; Zhao, Xiangmo, E-mail: xinshih86029@gmail.com; Hui, Fei, E-mail: xinshih86029@gmail.com

Clock synchronization in wireless sensor networks (WSNs) has been studied extensively in recent years and many protocols are put forward based on the point of statistical signal processing, which is an effective way to optimize accuracy. However, the accuracy derived from the statistical data can be improved mainly by sufficient packets exchange, which will consume the limited power resources greatly. In this paper, a reliable clock estimation using linear weighted fusion based on pairwise broadcast synchronization is proposed to optimize sync accuracy without expending additional sync packets. As a contribution, a linear weighted fusion scheme for multiple clock deviations ismore » constructed with the collaborative sensing of clock timestamp. And the fusion weight is defined by the covariance of sync errors for different clock deviations. Extensive simulation results show that the proposed approach can achieve better performance in terms of sync overhead and sync accuracy.« less

Statistical Mechanics of Viral Entry

NASA Astrophysics Data System (ADS)

Zhang, Yaojun; Dudko, Olga K.

2015-01-01

Viruses that have lipid-membrane envelopes infect cells by fusing with the cell membrane to release viral genes. Membrane fusion is known to be hindered by high kinetic barriers associated with drastic structural rearrangements—yet viral infection, which occurs by fusion, proceeds on remarkably short time scales. Here, we present a quantitative framework that captures the principles behind the invasion strategy shared by all enveloped viruses. The key to this strategy—ligand-triggered conformational changes in the viral proteins that pull the membranes together—is treated as a set of concurrent, bias field-induced activated rate processes. The framework results in analytical solutions for experimentally measurable characteristics of virus-cell fusion and enables us to express the efficiency of the viral strategy in quantitative terms. The predictive value of the theory is validated through simulations and illustrated through recent experimental data on influenza virus infection.

Synthetic neutron camera and spectrometer in JET based on AFSI-ASCOT simulations

NASA Astrophysics Data System (ADS)

Sirén, P.; Varje, J.; Weisen, H.; Koskela, T.; contributors, JET

2017-09-01

The ASCOT Fusion Source Integrator (AFSI) has been used to calculate neutron production rates and spectra corresponding to the JET 19-channel neutron camera (KN3) and the time-of-flight spectrometer (TOFOR) as ideal diagnostics, without detector-related effects. AFSI calculates fusion product distributions in 4D, based on Monte Carlo integration from arbitrary reactant distribution functions. The distribution functions were calculated by the ASCOT Monte Carlo particle orbit following code for thermal, NBI and ICRH particle reactions. Fusion cross-sections were defined based on the Bosch-Hale model and both DD and DT reactions have been included. Neutrons generated by AFSI-ASCOT simulations have already been applied as a neutron source of the Serpent neutron transport code in ITER studies. Additionally, AFSI has been selected to be a main tool as the fusion product generator in the complete analysis calculation chain: ASCOT - AFSI - SERPENT (neutron and gamma transport Monte Carlo code) - APROS (system and power plant modelling code), which encompasses the plasma as an energy source, heat deposition in plant structures as well as cooling and balance-of-plant in DEMO applications and other reactor relevant analyses. This conference paper presents the first results and validation of the AFSI DD fusion model for different auxiliary heating scenarios (NBI, ICRH) with very different fast particle distribution functions. Both calculated quantities (production rates and spectra) have been compared with experimental data from KN3 and synthetic spectrometer data from ControlRoom code. No unexplained differences have been observed. In future work, AFSI will be extended for synthetic gamma diagnostics and additionally, AFSI will be used as part of the neutron transport calculation chain to model real diagnostics instead of ideal synthetic diagnostics for quantitative benchmarking.

Performance evaluation of an asynchronous multisensor track fusion filter

NASA Astrophysics Data System (ADS)

Alouani, Ali T.; Gray, John E.; McCabe, D. H.

2003-08-01

Recently the authors developed a new filter that uses data generated by asynchronous sensors to produce a state estimate that is optimal in the minimum mean square sense. The solution accounts for communications delay between sensors platform and fusion center. It also deals with out of sequence data as well as latent data by processing the information in a batch-like manner. This paper compares, using simulated targets and Monte Carlo simulations, the performance of the filter to the optimal sequential processing approach. It was found that the new asynchronous Multisensor track fusion filter (AMSTFF) performance is identical to that of the extended sequential Kalman filter (SEKF), while the new filter updates its track at a much lower rate than the SEKF.

NUCLEAR HEATING IN LIF DOSEMETERS IN A FUSION NEUTRON FIELD, TRIAL OF DIRECT COMPARISON OF EXPERIMENTAL AND SIMULATED RESULTS.

PubMed

Pohorecki, Wladyslaw; Obryk, Barbara

2017-09-29

The results of nuclear heating measured by means of thermoluminescent dosemeters (TLD-LiF) in a Cu block irradiated by 14 MeV neutrons are presented. The integral Cu experiment relevant for verification of copper nuclear data at neutron energies characteristic for fusion facilities was performed in the ENEA FNG Laboratory at Frascati. Five types of TLDs were used: highly photon sensitive LiF:Mg,Cu,P (MCP-N), 7LiF:Mg,Cu,P (MCP-7) and standard, lower sensitivity LiF:Mg,Ti (MTS-N), 7LiF:Mg,Ti (MTS-7) and 6LiF:Mg,Ti (MTS-6). Calibration of the detectors was performed with gamma rays in terms of air-kerma (10 mGy of 137Cs air-kerma). Nuclear heating in the Cu block was also calculated with the use of MCNP transport code Nuclear heating in Cu and air in TLD's positions was calculated as well. The nuclear heating contribution from all simulated by MCNP6 code particles including protons, deuterons, alphas tritons and heavier ions produced by the neutron interactions were calculated. A trial of the direct comparison between experimental results and results of simulation was performed. © The Author 2017. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Neutron-Irradiated Samples as Test Materials for MPEX

DOE PAGES

Ellis, Ronald James; Rapp, Juergen

2015-10-09

Plasma Material Interaction (PMI) is a major concern in fusion reactor design and analysis. The Material-Plasma Exposure eXperiment (MPEX) will explore PMI under fusion reactor plasma conditions. Samples with accumulated displacements per atom (DPA) damage produced by fast neutron irradiations in the High Flux Isotope Reactor (HFIR) at Oak Ridge National Laboratory (ORNL) will be studied in the MPEX facility. This paper presents assessments of the calculated induced radioactivity and resulting radiation dose rates of a variety of potential fusion reactor plasma-facing materials (such as tungsten). The scientific code packages MCNP and SCALE were used to simulate irradiation of themore » samples in HFIR including the generation and depletion of nuclides in the material and the subsequent composition, activity levels, gamma radiation fields, and resultant dose rates as a function of cooling time. A challenge of the MPEX project is to minimize the radioactive inventory in the preparation of the samples and the sample dose rates for inclusion in the MPEX facility.« less

Neutron counter based on beryllium activation

NASA Astrophysics Data System (ADS)

Bienkowska, B.; Prokopowicz, R.; Scholz, M.; Kaczmarczyk, J.; Igielski, A.; Karpinski, L.; Paducha, M.; Pytel, K.

2014-08-01

The fusion reaction occurring in DD plasma is followed by emission of 2.45 MeV neutrons, which carry out information about fusion reaction rate and plasma parameters and properties as well. Neutron activation of beryllium has been chosen for detection of DD fusion neutrons. The cross-section for reaction 9Be(n, α)6He has a useful threshold near 1 MeV, which means that undesirable multiple-scattered neutrons do not undergo that reaction and therefore are not recorded. The product of the reaction, 6He, decays with half-life T1/2 = 0.807 s emitting β- particles which are easy to detect. Large area gas sealed proportional detector has been chosen as a counter of β-particles leaving activated beryllium plate. The plate with optimized dimensions adjoins the proportional counter entrance window. Such set-up is also equipped with appropriate electronic components and forms beryllium neutron activation counter. The neutron flux density on beryllium plate can be determined from the number of counts. The proper calibration procedure needs to be performed, therefore, to establish such relation. The measurements with the use of known β-source have been done. In order to determine the detector response function such experiment have been modeled by means of MCNP5-the Monte Carlo transport code. It allowed proper application of the results of transport calculations of β- particles emitted from radioactive 6He and reaching proportional detector active volume. In order to test the counter system and measuring procedure a number of experiments have been performed on PF devices. The experimental conditions have been simulated by means of MCNP5. The correctness of simulation outcome have been proved by measurements with known radioactive neutron source. The results of the DD fusion neutron measurements have been compared with other neutron diagnostics.

A precise and accurate acupoint location obtained on the face using consistency matrix pointwise fusion method.

PubMed

Yanq, Xuming; Ye, Yijun; Xia, Yong; Wei, Xuanzhong; Wang, Zheyu; Ni, Hongmei; Zhu, Ying; Xu, Lingyu

2015-02-01

To develop a more precise and accurate method, and identified a procedure to measure whether an acupoint had been correctly located. On the face, we used an acupoint location from different acupuncture experts and obtained the most precise and accurate values of acupoint location based on the consistency information fusion algorithm, through a virtual simulation of the facial orientation coordinate system. Because of inconsistencies in each acupuncture expert's original data, the system error the general weight calculation. First, we corrected each expert of acupoint location system error itself, to obtain a rational quantification for each expert of acupuncture and moxibustion acupoint location consistent support degree, to obtain pointwise variable precision fusion results, to put every expert's acupuncture acupoint location fusion error enhanced to pointwise variable precision. Then, we more effectively used the measured characteristics of different acupuncture expert's acupoint location, to improve the measurement information utilization efficiency and acupuncture acupoint location precision and accuracy. Based on using the consistency matrix pointwise fusion method on the acupuncture experts' acupoint location values, each expert's acupoint location information could be calculated, and the most precise and accurate values of each expert's acupoint location could be obtained.

Compressive hyperspectral and multispectral imaging fusion

NASA Astrophysics Data System (ADS)

Espitia, Óscar; Castillo, Sergio; Arguello, Henry

2016-05-01

Image fusion is a valuable framework which combines two or more images of the same scene from one or multiple sensors, allowing to improve the resolution of the images and increase the interpretable content. In remote sensing a common fusion problem consists of merging hyperspectral (HS) and multispectral (MS) images that involve large amount of redundant data, which ignores the highly correlated structure of the datacube along the spatial and spectral dimensions. Compressive HS and MS systems compress the spectral data in the acquisition step allowing to reduce the data redundancy by using different sampling patterns. This work presents a compressed HS and MS image fusion approach, which uses a high dimensional joint sparse model. The joint sparse model is formulated by combining HS and MS compressive acquisition models. The high spectral and spatial resolution image is reconstructed by using sparse optimization algorithms. Different fusion spectral image scenarios are used to explore the performance of the proposed scheme. Several simulations with synthetic and real datacubes show promising results as the reliable reconstruction of a high spectral and spatial resolution image can be achieved by using as few as just the 50% of the datacube.

Multispecies exclusion process with fusion and fission of rods: A model inspired by intraflagellar transport

NASA Astrophysics Data System (ADS)

Patra, Swayamshree; Chowdhury, Debashish

2018-01-01

We introduce a multispecies exclusion model where length-conserving probabilistic fusion and fission of the hard rods are allowed. Although all rods enter the system with the same initial length ℓ =1 , their length can keep changing, because of fusion and fission, as they move in a step-by-step manner towards the exit. Two neighboring hard rods of lengths ℓ1 and ℓ2 can fuse into a single rod of longer length ℓ =ℓ1+ℓ2 provided ℓ ≤N . Similarly, length-conserving fission of a rod of length ℓ'≤N results in two shorter daughter rods. Based on the extremum current hypothesis, we plot the phase diagram of the model under open boundary conditions utilizing the results derived for the same model under periodic boundary condition using mean-field approximation. The density profile and the flux profile of rods are in excellent agreement with computer simulations. Although the fusion and fission of the rods are motivated by similar phenomena observed in intraflagellar transport (IFT) in eukaryotic flagella, this exclusion model is too simple to account for the quantitative experimental data for any specific organism. Nevertheless, the concepts of "flux profile" and "transition zone" that emerge from the interplay of fusion and fission in this model are likely to have important implications for IFT and for other similar transport phenomena in long cell protrusions.

Self-consistent gyrokinetic modeling of neoclassical and turbulent impurity transport

NASA Astrophysics Data System (ADS)

Estève, D.; Sarazin, Y.; Garbet, X.; Grandgirard, V.; Breton, S.; Donnel, P.; Asahi, Y.; Bourdelle, C.; Dif-Pradalier, G.; Ehrlacher, C.; Emeriau, C.; Ghendrih, Ph.; Gillot, C.; Latu, G.; Passeron, C.

2018-03-01

Trace impurity transport is studied with the flux-driven gyrokinetic GYSELA code (Grandgirard et al 2016 Comput. Phys. Commun. 207 35). A reduced and linearized multi-species collision operator has been recently implemented, so that both neoclassical and turbulent transport channels can be treated self-consistently on an equal footing. In the Pfirsch-Schlüter regime that is probably relevant for tungsten, the standard expression for the neoclassical impurity flux is shown to be recovered from gyrokinetics with the employed collision operator. Purely neoclassical simulations of deuterium plasma with trace impurities of helium, carbon and tungsten lead to impurity diffusion coefficients, inward pinch velocities due to density peaking, and thermo-diffusion terms which quantitatively agree with neoclassical predictions and NEO simulations (Belli et al 2012 Plasma Phys. Control. Fusion 54 015015). The thermal screening factor appears to be less than predicted analytically in the Pfirsch-Schlüter regime, which can be detrimental to fusion performance. Finally, self-consistent nonlinear simulations have revealed that the tungsten impurity flux is not the sum of turbulent and neoclassical fluxes computed separately, as is usually assumed. The synergy partly results from the turbulence-driven in-out poloidal asymmetry of tungsten density. This result suggests the need for self-consistent simulations of impurity transport, i.e. including both turbulence and neoclassical physics, in view of quantitative predictions for ITER.

The Positioning Accuracy of BAUV Using Fusion of Data from USBL System and Movement Parameters Measurements

PubMed Central

Krzysztof, Naus; Aleksander, Nowak

2016-01-01

The article presents a study of the accuracy of estimating the position coordinates of BAUV (Biomimetic Autonomous Underwater Vehicle) by the extended Kalman filter (EKF) method. The fusion of movement parameters measurements and position coordinates fixes was applied. The movement parameters measurements are carried out by on-board navigation devices, while the position coordinates fixes are done by the USBL (Ultra Short Base Line) system. The problem of underwater positioning and the conceptual design of the BAUV navigation system constructed at the Naval Academy (Polish Naval Academy—PNA) are presented in the first part of the paper. The second part consists of description of the evaluation results of positioning accuracy, the genesis of the problem of selecting method for underwater positioning, and the mathematical description of the method of estimating the position coordinates using the EKF method by the fusion of measurements with on-board navigation and measurements obtained with the USBL system. The main part contains a description of experimental research. It consists of a simulation program of navigational parameter measurements carried out during the BAUV passage along the test section. Next, the article covers the determination of position coordinates on the basis of simulated parameters, using EKF and DR methods and the USBL system, which are then subjected to a comparative analysis of accuracy. The final part contains systemic conclusions justifying the desirability of applying the proposed fusion method of navigation parameters for the BAUV positioning. PMID:27537884

The Positioning Accuracy of BAUV Using Fusion of Data from USBL System and Movement Parameters Measurements.

PubMed

Krzysztof, Naus; Aleksander, Nowak

2016-08-15

The article presents a study of the accuracy of estimating the position coordinates of BAUV (Biomimetic Autonomous Underwater Vehicle) by the extended Kalman filter (EKF) method. The fusion of movement parameters measurements and position coordinates fixes was applied. The movement parameters measurements are carried out by on-board navigation devices, while the position coordinates fixes are done by the USBL (Ultra Short Base Line) system. The problem of underwater positioning and the conceptual design of the BAUV navigation system constructed at the Naval Academy (Polish Naval Academy-PNA) are presented in the first part of the paper. The second part consists of description of the evaluation results of positioning accuracy, the genesis of the problem of selecting method for underwater positioning, and the mathematical description of the method of estimating the position coordinates using the EKF method by the fusion of measurements with on-board navigation and measurements obtained with the USBL system. The main part contains a description of experimental research. It consists of a simulation program of navigational parameter measurements carried out during the BAUV passage along the test section. Next, the article covers the determination of position coordinates on the basis of simulated parameters, using EKF and DR methods and the USBL system, which are then subjected to a comparative analysis of accuracy. The final part contains systemic conclusions justifying the desirability of applying the proposed fusion method of navigation parameters for the BAUV positioning.

Integrated Reflection Seismic Monitoring and Reservoir Modeling for Geologic CO2 Sequestration

DOE Office of Scientific and Technical Information (OSTI.GOV)

John Rogers

The US DOE/NETL CCS MVA program funded a project with Fusion Petroleum Technologies Inc. (now SIGMA) to model the proof of concept of using sparse seismic data in the monitoring of CO{sub 2} injected into saline aquifers. The goal of the project was to develop and demonstrate an active source reflection seismic imaging strategy based on deployment of spatially sparse surface seismic arrays. The primary objective was to test the feasibility of sparse seismic array systems to monitor the CO{sub 2} plume migration injected into deep saline aquifers. The USDOE/RMOTC Teapot Dome (Wyoming) 3D seismic and reservoir data targeting themore » Crow Mountain formation was used as a realistic proxy to evaluate the feasibility of the proposed methodology. Though the RMOTC field has been well studied, the Crow Mountain as a saline aquifer has not been studied previously as a CO{sub 2} sequestration (storage) candidate reservoir. A full reprocessing of the seismic data from field tapes that included prestack time migration (PSTM) followed by prestack depth migration (PSDM) was performed. A baseline reservoir model was generated from the new imaging results that characterized the faults and horizon surfaces of the Crow Mountain reservoir. The 3D interpretation was integrated with the petrophysical data from available wells and incorporated into a geocellular model. The reservoir structure used in the geocellular model was developed using advanced inversion technologies including Fusion's ThinMAN{trademark} broadband spectral inversion. Seal failure risk was assessed using Fusion's proprietary GEOPRESS{trademark} pore pressure and fracture pressure prediction technology. CO{sub 2} injection was simulated into the Crow Mountain with a commercial reservoir simulator. Approximately 1.2MM tons of CO{sub 2} was simulated to be injected into the Crow Mountain reservoir over 30 years and subsequently let 'soak' in the reservoir for 970 years. The relatively small plume developed from this injection was observed migrating due to gravity to the apexes of the double anticline in the Crow Mountain reservoir of the Teapot dome. Four models were generated from the reservoir simulation task of the project which included three saturation models representing snapshots at different times during and after simulated CO{sub 2} injection and a fully saturated CO{sub 2} fluid substitution model. The saturation models were used along with a Gassmann fluid substitution model for CO{sub 2} to perform fluid volumetric substitution in the Crow Mountain formation. The fluid substitution resulted in a velocity and density model for the 3D volume at each saturation condition that was used to generate a synthetic seismic survey. FPTI's (Fusion Petroleum Technologies Inc.) proprietary SeisModelPRO{trademark} full acoustic wave equation software was used to simulate acquisition of a 3D seismic survey on the four models over a subset of the field area. The simulated acquisition area included the injection wells and the majority of the simulated plume area.« less

Quasi-monoenergetic ion generation by hole-boring radiation pressure acceleration in inhomogeneous plasmas using tailored laser pulses

DOE Office of Scientific and Technical Information (OSTI.GOV)

Weng, S. M., E-mail: weng-sm@ile.osaka-u.ac.jp; Murakami, M.; Azechi, H.

It is proposed that laser hole-boring at a steady speed in inhomogeneous overdense plasma can be realized by the use of temporally tailored intense laser pulses, producing high-fluence quasi-monoenergetic ion beams. A general temporal profile of such laser pulses is formulated for arbitrary plasma density distribution. As an example, for a precompressed deuterium-tritium fusion target with an exponentially increasing density profile, its matched laser profile for steady hole-boring is given theoretically and verified numerically by particle-in-cell simulations. Furthermore, we propose to achieve fast ignition by the in-situ hole-boring accelerated ions using a tailored laser pulse. Simulations show that the effectivemore » energy fluence, conversion efficiency, energy spread, and collimation of the resulting ion beam can be significantly improved as compared to those found with un-tailored laser profiles. For the fusion fuel with an areal density of 1.5 g cm{sup –2}, simulation indicates that it is promising to realize fast ion ignition by using a tailored driver pulse with energy about 65 kJ.« less

Advances in simulation of wave interactions with extended MHD phenomena

NASA Astrophysics Data System (ADS)

Batchelor, D.; Abla, G.; D'Azevedo, E.; Bateman, G.; Bernholdt, D. E.; Berry, L.; Bonoli, P.; Bramley, R.; Breslau, J.; Chance, M.; Chen, J.; Choi, M.; Elwasif, W.; Foley, S.; Fu, G.; Harvey, R.; Jaeger, E.; Jardin, S.; Jenkins, T.; Keyes, D.; Klasky, S.; Kruger, S.; Ku, L.; Lynch, V.; McCune, D.; Ramos, J.; Schissel, D.; Schnack, D.; Wright, J.

2009-07-01

The Integrated Plasma Simulator (IPS) provides a framework within which some of the most advanced, massively-parallel fusion modeling codes can be interoperated to provide a detailed picture of the multi-physics processes involved in fusion experiments. The presentation will cover four topics: 1) recent improvements to the IPS, 2) application of the IPS for very high resolution simulations of ITER scenarios, 3) studies of resistive and ideal MHD stability in tokamk discharges using IPS facilities, and 4) the application of RF power in the electron cyclotron range of frequencies to control slowly growing MHD modes in tokamaks and initial evaluations of optimized location for RF power deposition.

Fusion boundary microstructure evolution in aluminum alloys

NASA Astrophysics Data System (ADS)

Kostrivas, Anastasios Dimitrios

2000-10-01

A melting technique was developed to simulate the fusion boundary of aluminum alloys using the GleebleRTM thermal simulator. Using a steel sleeve to contain the aluminum, samples were heated to incremental temperatures above the solidus temperature of a number of alloys. In alloy 2195, a 4wt%Cu-1wt%Li alloy, an equiaxed non-dendritic zone (EQZ) could be formed by heating in the temperature range from approximately 630 to 640°C. At temperatures above 640°C, solidification occurred by the normal epitaxial nucleation and growth mechanism. Fusion boundary behavior was also studied in alloys 5454-H34, 6061-T6, and 2219-T8. Additionally, experimental alloy compositions were produced by making bead on plate welds using an alloy 5454-H32 base metal and 5025 or 5087 filler metals. These filler metals contain zirconium and scandium additions, respectively, and were expected to influence nucleation and growth behavior. Both as-welded and welded/heat treated (540°C and 300°C) substrates were tested by melting simulation, resulting in dendritic and EQZ structures depending on composition and substrate condition. Orientation imaging microscopy (OIM(TM)) was employed to study the crystallographic character of the microstructures produced and to verify the mechanism responsible for EQZ formation. OIM(TM) proved that grains within the EQZ have random orientation. In all other cases, where the simulated microstructures were dendritic in nature, it was shown that epitaxy was the dominant mode of nucleation. The lack of any preferred crystallographic orientation relationship in the EQZ supports a theory proposed by Lippold et al that the EQZ is the result of heterogeneous nucleation within the weld unmixed zone. EDS analysis of the 2195 on STEM revealed particles with ternary composition consisted of Zr, Cu and Al and a tetragonal type crystallographic lattice. Microdiffraction line scans on EQZ grains in the alloy 2195 showed very good agreement between the measured Cu composition within the interior of the non-dendritic grains and the corresponding value the Scheil equation predicts for the first solid to form upon solidification for a binary Al-Cu alloy with identical Cu composition. In the context of the alloys, compositions and substrate conditions examined a mechanistic model for EQZ zone formation is proposed, helpful in adjusting base metal compositions and/or substrate conditions to control fusion boundary microstructure.

MHD simulation of plasma compression experiments

NASA Astrophysics Data System (ADS)

Reynolds, Meritt; Barsky, Sandra; de Vietien, Peter

2017-10-01

General Fusion (GF) is working to build a magnetized target fusion (MTF) power plant based on compression of magnetically-confined plasma by liquid metal. GF is testing this compression concept by collapsing solid aluminum liners onto plasmas formed by coaxial helicity injection in a series of experiments called PCS (Plasma Compression, Small). We simulate the PCS experiments using the finite-volume MHD code VAC. The single-fluid plasma model includes temperature-dependent resistivity and anisotropic heat transport. The time-dependent curvilinear mesh for MHD simulation is derived from LS-DYNA simulations of actual field tests of liner implosion. We will discuss how 3D simulations reproduced instability observed in the PCS13 experiment and correctly predicted stabilization of PCS14 by ramping the shaft current during compression. We will also present a comparison of simulated Mirnov and x-ray diagnostics with experimental measurements indicating that PCS14 compressed well to a linear compression ratio of 2.5:1.

Quantifying Fusion Born Ion Populations in Magnetically Confined Plasmas using Ion Cyclotron Emission

NASA Astrophysics Data System (ADS)

Carbajal, L.; Dendy, R. O.; Chapman, S. C.; Cook, J. W. S.

2017-03-01

Ion cyclotron emission (ICE) offers a unique promise as a diagnostic of the fusion born alpha-particle population in magnetically confined plasmas. Pioneering observations from JET and TFTR found that ICE intensity PICE scales approximately linearly with the measured neutron flux from fusion reactions, and with the inferred concentration, nα/ni, of fusion born alpha particles confined within the plasma. We present fully nonlinear self-consistent kinetic simulations that reproduce this scaling for the first time. This resolves a long-standing question in the physics of fusion alpha-particle confinement and stability in magnetic confinement fusion plasmas. It confirms the magnetoacoustic cyclotron instability as the likely emission mechanism and greatly strengthens the basis for diagnostic exploitation of ICE in future burning plasmas.

Quantifying Fusion Born Ion Populations in Magnetically Confined Plasmas using Ion Cyclotron Emission.

PubMed

Carbajal, L; Dendy, R O; Chapman, S C; Cook, J W S

2017-03-10

Ion cyclotron emission (ICE) offers a unique promise as a diagnostic of the fusion born alpha-particle population in magnetically confined plasmas. Pioneering observations from JET and TFTR found that ICE intensity P_{ICE} scales approximately linearly with the measured neutron flux from fusion reactions, and with the inferred concentration, n_{α}/n_{i}, of fusion born alpha particles confined within the plasma. We present fully nonlinear self-consistent kinetic simulations that reproduce this scaling for the first time. This resolves a long-standing question in the physics of fusion alpha-particle confinement and stability in magnetic confinement fusion plasmas. It confirms the magnetoacoustic cyclotron instability as the likely emission mechanism and greatly strengthens the basis for diagnostic exploitation of ICE in future burning plasmas.

Modeling Electrothermal Plasma with Boundary Layer Effects

NASA Astrophysics Data System (ADS)

AlMousa, Nouf Mousa A.

Electrothermal plasma sources produce high-density (1023-10 28 /m3) and high temperature (1-5 eV) plasmas that are of interest for a variety of applications such as hypervelocity launch devices, fusion reactor pellet injectors, and pulsed thrusters for small satellites. Also, the high heat flux (up to 100 GW/m2) and high pressure (100s MPa) of electrothermal (ET) plasmas allow for the use of such facilities as a source of high heat flux to simulate off-normal events in Tokamak fusion reactors. Off-normal events like disruptions, thermal and current quenches, are the perfect recipes for damage of plasma facing components (PFC). Successful operation of a fusion reactor requires comprehensive understanding of material erosion behavior. The extremely high heat fluxes deposited in PFCs melt and evaporate or directly sublime the exposed surfaces, which results in a thick vapor/melt boundary layer adjacent to the solid wall structure. The accumulating boundary layers provide a self-protecting nature by attenuating the radiant energy transport to the PFCs. The ultimate goal of this study is to develop a reliable tool to adequately simulate the effect of the boundary layers on the formation and flow of the energetic ET plasma and its impact on exposed surfaces erosion under disruption like conditions. This dissertation is a series of published journals/conferences papers. The first paper verified the existence of the vapor shield that evolved at the boundary layer under the typical operational conditions of the NC State University ET plasma facilities PIPE and SIRENS. Upon the verification of the vapor shield, the second paper proposed novel model to simulate the evolution of the boundary layer and its effectiveness in providing a self-protecting nature for the exposed plasma facing surfaces. The developed models simulate the radiant heat flux attenuation through an optically thick boundary layer. The models were validated by comparing the simulation results to experimental data taken from the ET plasma facilities. Upon validation of the boundary layer models, computational experiments were conducted with the purpose of evaluation the PFCs' erosion during plasma disruption in Tokamak fusion reactors. Erosion of a set of selected low-Z and high-Z materials were analyzed and discussed. For metallic plasma facing materials under the impact of hard and long time-scale disruption events, melting and melt-layer splashing become dominate erosion mechanisms during plasma-material interaction. In order to realistically assess the erosion of the metallic fusion reactor components, the fourth paper accounts for the various mechanisms by which material evolved from PFCs due to melting and vaporization, with a developed melting and splattering/splashing model incorporated in the ET plasma code. Also, the shielding effect associated with melt-layer and vapor-layer is investigated. The quantitative results of material erosion with the boundary layer effects including a vapor layer, melt layer and splashing effects is a new model and an important step towards achieving a better understanding of plasma-material interactions under exposure to such high heat flux conditions.

Biomechanical effects of fusion levels on the risk of proximal junctional failure and kyphosis in lumbar spinal fusion surgery.

PubMed

Park, Won Man; Choi, Dae Kyung; Kim, Kyungsoo; Kim, Yongjung J; Kim, Yoon Hyuk

2015-12-01

Spinal fusion surgery is a widely used surgical procedure for sagittal realignment. Clinical studies have reported that spinal fusion may cause proximal junctional kyphosis and failure with disc failure, vertebral fracture, and/or failure at the implant-bone interface. However, the biomechanical injury mechanisms of proximal junctional kyphosis and failure remain unclear. A finite element model of the thoracolumbar spine was used. Nine fusion models with pedicle screw systems implanted at the L2-L3, L3-L4, L4-L5, L5-S1, L2-L4, L3-L5, L4-S1, L2-L5, and L3-S1 levels were developed based on the respective surgical protocols. The developed models simulated flexion-extension using hybrid testing protocol. When spinal fusion was performed at more distal levels, particularly at the L5-S1 level, the following biomechanical properties increased during flexion-extension: range of motion, stress on the annulus fibrosus fibers and vertebra at the adjacent motion segment, and the magnitude of axial forces on the pedicle screw at the uppermost instrumented vertebra. The results of this study demonstrate that more distal fusion levels, particularly in spinal fusion including the L5-S1 level, lead to greater increases in the risk of proximal junctional kyphosis and failure, as evidenced by larger ranges of motion, higher stresses on fibers of the annulus fibrosus and vertebra at the adjacent segment, and higher axial forces on the screw at the uppermost instrumented vertebra in flexion-extension. Therefore, fusion levels should be carefully selected to avoid proximal junctional kyphosis and failure. Copyright © 2015 Elsevier Ltd. All rights reserved.

Neutron imaging with bubble chambers for inertial confinement fusion

NASA Astrophysics Data System (ADS)

Ghilea, Marian C.

One of the main methods to obtain energy from controlled thermonuclear fusion is inertial confinement fusion (ICF), a process where nuclear fusion reactions are initiated by heating and compressing a fuel target, typically in the form of a pellet that contains deuterium and tritium, relying on the inertia of the fuel mass to provide confinement. In inertial confinement fusion experiments, it is important to distinguish failure mechanisms of the imploding capsule and unambiguously diagnose compression and hot spot formation in the fuel. Neutron imaging provides such a technique and bubble chambers are capable of generating higher resolution images than other types of neutron detectors. This thesis explores the use of a liquid bubble chamber to record high yield 14.1 MeV neutrons resulting from deuterium-tritium fusion reactions on ICF experiments. A design tool to deconvolve and reconstruct penumbral and pinhole neutron images was created, using an original ray tracing concept to simulate the neutron images. The design tool proved that misalignment and aperture fabrication errors can significantly decrease the resolution of the reconstructed neutron image. A theoretical model to describe the mechanism of bubble formation was developed. A bubble chamber for neutron imaging with Freon 115 as active medium was designed and implemented for the OMEGA laser system. High neutron yields resulting from deuterium-tritium capsule implosions were recorded. The bubble density was too low for neutron imaging on OMEGA but agreed with the model of bubble formation. The research done in here shows that bubble detectors are a promising technology for the higher neutron yields expected at National Ignition Facility (NIF).

Lipid tail protrusions initiate spontaneous insertion of charged, amphiphilic nanoparticles into lipid bilayers

NASA Astrophysics Data System (ADS)

van Lehn, Reid; Ricci, Maria; Carney, Randy; Voitchovsky, Kislon; Stellacci, Francesco; Alexander-Katz, Alfredo

2014-03-01

Vesicle fusion is a primary mechanism used to mediate the uptake and trafficking of materials both into and between cells. The pathway of vesicle fusion involves the formation of a lipid stalk in which the hydrophobic core regions of two closely associated bilayers merge. The transition state for stalk formation requires the transient protrusion of hydrophobic lipid tails into solvent; favorable contact between these hydrophobic tails then drives stalk creation. In this work, we use unbiased atomistic molecular dynamics simulations to show that lipid tail protrusions can also induce the insertion of charged, amphiphilic nanoparticles (NPs) into lipid bilayers. As in the case of vesicle fusion, the rate-limiting step for NP-bilayer fusion is the stochastic protrusion of aliphatic lipid tails into solvent and into contact with hydrophobic material in the amphiphilic NP monolayer. We confirm our predictions with experiments on supported lipid bilayers. The strong agreement between simulation and experiments indicates that the pre-stalk transition associated with vesicle fusion may be a general mechanism for the insertion of amphiphilic nano-objects that could be prominent in biological systems given the widespread use of NPs in applications ranging from drug delivery to biosensing.

Experimental demonstration of ion extraction from magnetic thrust chamber for laser fusion rocket

NASA Astrophysics Data System (ADS)

Saito, Naoya; Yamamoto, Naoji; Morita, Taichi; Edamoto, Masafumi; Nakashima, Hideki; Fujioka, Shinsuke; Yogo, Akifumi; Nishimura, Hiroaki; Sunahara, Atsushi; Mori, Yoshitaka; Johzaki, Tomoyuki

2018-05-01

A magnetic thrust chamber is an important system of a laser fusion rocket, in which the plasma kinetic energy is converted into vehicle thrust by a magnetic field. To investigate the plasma extraction from the system, the ions in a plasma are diagnosed outside the system by charge collectors. The results clearly show that the ion extraction does not strongly depend on the magnetic field strength when the energy ratio of magnetic field to plasma is greater than 4.3, and the magnetic field pushes back the plasma to generate a thrust, as previously suggested by numerical simulation and experiments.

Zonal flow generation in inertial confinement fusion implosions

DOE PAGES

Peterson, J. L.; Humbird, K. D.; Field, J. E.; ...

2017-03-06

A supervised machine learning algorithm trained on a multi-petabyte dataset of inertial confinement fusion simulations has identified a class of implosions that robustly achieve high yield, even in the presence of drive variations and hydrodynamic perturbations. These implosions are purposefully driven with a time-varying asymmetry, such that coherent flow generation during hotspot stagnation forces the capsule to self-organize into an ovoid, a shape that appears to be more resilient to shell perturbations than spherical designs. Here this new class of implosions, whose configurations are reminiscent of zonal flows in magnetic fusion devices, may offer a path to robust inertial fusion.

Zonal flow generation in inertial confinement fusion implosions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Peterson, J. L.; Humbird, K. D.; Field, J. E.

A supervised machine learning algorithm trained on a multi-petabyte dataset of inertial confinement fusion simulations has identified a class of implosions that robustly achieve high yield, even in the presence of drive variations and hydrodynamic perturbations. These implosions are purposefully driven with a time-varying asymmetry, such that coherent flow generation during hotspot stagnation forces the capsule to self-organize into an ovoid, a shape that appears to be more resilient to shell perturbations than spherical designs. Here this new class of implosions, whose configurations are reminiscent of zonal flows in magnetic fusion devices, may offer a path to robust inertial fusion.

Three-dimensional particle simulation of heavy-ion fusion beams

DOE Office of Scientific and Technical Information (OSTI.GOV)

Friedman, A.; Grote, D.P.; Haber, I.

1992-07-01

The beams in a heavy-ion-beam-driven inertial fusion (HIF) accelerator are collisionless, nonneutral plasmas, confined by applied magnetic and electric fields. These space-charge-dominated beams must be focused onto small (few mm) spots at the fusion target, and so preservation of a small emittance is crucial. The nonlinear beam self-fields can lead to emittance growth, and so a self-consistent field description is needed. To this end, a multidimensional particle simulation code, WARP (Friedman {ital et} {ital al}., Part. Accel. {bold 37}-{bold 38}, 131 (1992)), has been developed and is being used to study the transport of HIF beams. The code's three-dimensional (3-D)more » package combines features of an accelerator code and a particle-in-cell plasma simulation. Novel techniques allow it to follow beams through many accelerator elements over long distances and around bends. This paper first outlines the algorithms employed in WARP. A number of applications and corresponding results are then presented. These applications include studies of: beam drift-compression in a misaligned lattice of quadrupole focusing magnets; beam equilibria, and the approach to equilibrium; and the MBE-4 experiment ({ital AIP} {ital Conference} {ital Proceedings} 152 (AIP, New York, 1986), p. 145) recently concluded at Lawrence Berkeley Laboratory (LBL). Finally, 3-D simulations of bent-beam dynamics relevant to the planned Induction Linac Systems Experiments (ILSE) (Fessenden, Nucl. Instrum. Methods Plasma Res. A {bold 278}, 13 (1989)) at LBL are described. Axially cold beams are observed to exhibit little or no root-mean-square emittance growth at midpulse in transiting a (sharp) bend. Axially hot beams, in contrast, do exhibit some emittance growth.« less

Lenard-Balescu calculations and classical molecular dynamics simulations of electrical and thermal conductivities of hydrogen plasmas

DOE PAGES

Whitley, Heather D.; Scullard, Christian R.; Benedict, Lorin X.; ...

2014-12-04

Here, we present a discussion of kinetic theory treatments of linear electrical and thermal transport in hydrogen plasmas, for a regime of interest to inertial confinement fusion applications. In order to assess the accuracy of one of the more involved of these approaches, classical Lenard-Balescu theory, we perform classical molecular dynamics simulations of hydrogen plasmas using 2-body quantum statistical potentials and compute both electrical and thermal conductivity from out particle trajectories using the Kubo approach. Our classical Lenard-Balescu results employing the identical statistical potentials agree well with the simulations.

Plasma confinement theory and transport simulation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ross, D.W.

The objectives are: (1) to advance the transport studies of tokamaks, including development and maintenance of the Magnetic Fusion Energy Database, and (2) to provide theoretical interpretation, modeling and equilibrium and stability studies for TEXT-Upgrade. Recent reports, publications, and conference presentations of the Fusion Research Center are listed.

Amphiphilic gold nanoparticles as modulators of lipid membrane fusion

NASA Astrophysics Data System (ADS)

Tahir, Mukarram; Alexander-Katz, Alfredo

The fusion of lipid membranes is central to biological functions like inter-cellular transport and signaling and is coordinated by proteins of the soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) superfamily. We utilize molecular dynamics simulations to demonstrate that gold nanoparticles functionalized with a mixed-monolayer of hydrophobic and hydrophilic alkanethiol ligands can act as synthetic analogues of these fusion proteins and mediate lipid membrane fusion by catalyzing the formation of a toroidal stalk between adjacent membranes and enabling the formation of a fusion pore upon influx of Ca2+ into the exterior solvent. The fusion pathway enabled by these synthetic nanostructures is analogous to the regulated fast fusion pathway observed during synaptic vesicle fusion; it therefore provides novel physical insights into this important biological process while also being relevant in a number of single-cell therapeutic applications. Computational resources from NSF XSEDE contract TG-DMR130042. Financial support from DOE CSGF fellowship DE-FG02-97ER25308.

Multispectral image fusion using neural networks

NASA Technical Reports Server (NTRS)

Kagel, J. H.; Platt, C. A.; Donaven, T. W.; Samstad, E. A.

1990-01-01

A prototype system is being developed to demonstrate the use of neural network hardware to fuse multispectral imagery. This system consists of a neural network IC on a motherboard, a circuit card assembly, and a set of software routines hosted by a PC-class computer. Research in support of this consists of neural network simulations fusing 4 to 7 bands of Landsat imagery and fusing (separately) multiple bands of synthetic imagery. The simulations, results, and a description of the prototype system are presented.

Decision-level fusion of SAR and IR sensor information for automatic target detection

NASA Astrophysics Data System (ADS)

Cho, Young-Rae; Yim, Sung-Hyuk; Cho, Hyun-Woong; Won, Jin-Ju; Song, Woo-Jin; Kim, So-Hyeon

2017-05-01

We propose a decision-level architecture that combines synthetic aperture radar (SAR) and an infrared (IR) sensor for automatic target detection. We present a new size-based feature, called target-silhouette to reduce the number of false alarms produced by the conventional target-detection algorithm. Boolean Map Visual Theory is used to combine a pair of SAR and IR images to generate the target-enhanced map. Then basic belief assignment is used to transform this map into a belief map. The detection results of sensors are combined to build the target-silhouette map. We integrate the fusion mass and the target-silhouette map on the decision level to exclude false alarms. The proposed algorithm is evaluated using a SAR and IR synthetic database generated by SE-WORKBENCH simulator, and compared with conventional algorithms. The proposed fusion scheme achieves higher detection rate and lower false alarm rate than the conventional algorithms.

Generalized Lawson Criteria for Inertial Confinement Fusion

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tipton, Robert E.

2015-08-27

The Lawson Criterion was proposed by John D. Lawson in 1955 as a general measure of the conditions necessary for a magnetic fusion device to reach thermonuclear ignition. Over the years, similar ignition criteria have been proposed which would be suitable for Inertial Confinement Fusion (ICF) designs. This paper will compare and contrast several ICF ignition criteria based on Lawson’s original ideas. Both analytical and numerical results will be presented which will demonstrate that although the various criteria differ in some details, they are closely related and perform similarly as ignition criteria. A simple approximation will also be presented whichmore » allows the inference of each ignition parameter directly from the measured data taken on most shots fired at the National Ignition Facility (NIF) with a minimum reliance on computer simulations. Evidence will be presented which indicates that the experimentally inferred ignition parameters on the best NIF shots are very close to the ignition threshold.« less

Multisensor Parallel Largest Ellipsoid Distributed Data Fusion with Unknown Cross-Covariances

PubMed Central

Liu, Baoyu; Zhan, Xingqun; Zhu, Zheng H.

2017-01-01

As the largest ellipsoid (LE) data fusion algorithm can only be applied to two-sensor system, in this contribution, parallel fusion structure is proposed to introduce the LE algorithm into a multisensor system with unknown cross-covariances, and three parallel fusion structures based on different estimate pairing methods are presented and analyzed. In order to assess the influence of fusion structure on fusion performance, two fusion performance assessment parameters are defined as Fusion Distance and Fusion Index. Moreover, the formula for calculating the upper bounds of actual fused error covariances of the presented multisensor LE fusers is also provided. Demonstrated with simulation examples, the Fusion Index indicates fuser’s actual fused accuracy and its sensitivity to the sensor orders, as well as its robustness to the accuracy of newly added sensors. Compared to the LE fuser with sequential structure, the LE fusers with proposed parallel structures not only significantly improve their properties in these aspects, but also embrace better performances in consistency and computation efficiency. The presented multisensor LE fusers generally have better accuracies than covariance intersection (CI) fusion algorithm and are consistent when the local estimates are weakly correlated. PMID:28661442

Ion-kinetic simulations of D- 3He gas-filled inertial confinement fusion target implosions with moderate to large Knudsen number

DOE PAGES

Larroche, O.; Rinderknecht, H. G.; Rosenberg, M. J.; ...

2016-01-06

Experiments designed to investigate the transition to non-collisional behavior in D 3He-gas inertial confinement fusion target implosions display increasingly large discrepancies with respect to simulations by standard hydrodynamics codes as the expected ion mean-free-paths λ c increase with respect to the target radius R (i.e., when the Knudsen number N K = λ c/R grows). To take properly into account large N K's, multi-ion-species Vlasov-Fokker-Planck computations of the inner gas in the capsules have been performed, for two different values of N K, one moderate and one large. The results, including nuclear yield, reactivity-weighted ion temperatures, nuclear emissivities, and surfacemore » brightness, have been compared with the experimental data and with the results of hydrodynamical simulations, some of which include an ad hocmodeling of kinetic effects. The experimental results are quite accurately rendered by the kinetic calculations in the smaller-N K case, much better than by the hydrodynamical calculations. The kinetic effects at play in this case are thus correctly understood. However, in the higher-N K case, the agreement is much worse. Furthermore, the remaining discrepancies are shown to arise from kinetic phenomena (e.g., inter-species diffusion) occurring at the gas-pusher interface, which should be investigated in the future work.« less

A comparative study on generating simulated Landsat NDVI images using data fusion and regression method-the case of the Korean Peninsula.

PubMed

Lee, Mi Hee; Lee, Soo Bong; Eo, Yang Dam; Kim, Sun Woong; Woo, Jung-Hun; Han, Soo Hee

2017-07-01

Landsat optical images have enough spatial and spectral resolution to analyze vegetation growth characteristics. But, the clouds and water vapor degrade the image quality quite often, which limits the availability of usable images for the time series vegetation vitality measurement. To overcome this shortcoming, simulated images are used as an alternative. In this study, weighted average method, spatial and temporal adaptive reflectance fusion model (STARFM) method, and multilinear regression analysis method have been tested to produce simulated Landsat normalized difference vegetation index (NDVI) images of the Korean Peninsula. The test results showed that the weighted average method produced the images most similar to the actual images, provided that the images were available within 1 month before and after the target date. The STARFM method gives good results when the input image date is close to the target date. Careful regional and seasonal consideration is required in selecting input images. During summer season, due to clouds, it is very difficult to get the images close enough to the target date. Multilinear regression analysis gives meaningful results even when the input image date is not so close to the target date. Average R 2 values for weighted average method, STARFM, and multilinear regression analysis were 0.741, 0.70, and 0.61, respectively.

Modeling the structure and thermodynamics of ferrocenium-based ionic liquids.

PubMed

Bernardes, Carlos E S; Mochida, Tomoyuki; Canongia Lopes, José N

2015-04-21

A new force-field for the description of ferrocenium-based ionic liquids is reported. The proposed model was validated by confronting Molecular Dynamics simulations results with available experimental data-enthalpy of fusion, crystalline structure and liquid density-for a series of 1-alkyl-2,3,4,5,6,7,8,9-octamethylferrocenium bis(trifluoromethylsulfonyl)imide ionic liquids, [CnFc][NTf2] (3 ≤ n ≤ 10). The model is able to reproduce the densities and enthalpies of fusion with deviations smaller than 2.6% and 4.8 kJ mol(-1), respectively. The MD simulation trajectories were also used to compute relevant structural information for the different [CnFc][NTf2] ionic liquids. The results show that, unlike other ILs, the alkyl side chains present in the cations are able to interact directly with the ferrocenium core of other ions. Even the ferrocenium charged cores (with relatively mild charge densities) are able to form small contact aggregates. This causes the partial rupture of the polar network and precludes the formation of extended nano-segregated polar-nonpolar domains normally observed in other ionic liquids.

Z-Pinch Plasma Neutron Sources

DTIC Science & Technology

2006-03-24

deuterium into 9 to 14 keV (around 10 keV), which is well in the fusion energy range we are interested in. To make plasma radiation sources work, we...showing the 1-D dynamics of the pinch plasma implosion, temperature, fusion energy production and deposition for the conditions of shot Z1422. The minimum...histories of ion and electron temperatures, fusion energy production and energy deposition in ID RMHD run modeling deuterium shot Z1422. In our simulations

Virtually-augmented interfaces for tactical aircraft.

PubMed

Haas, M W

1995-05-01

The term Fusion Interface is defined as a class of interface which integrally incorporates both virtual and non-virtual concepts and devices across the visual, auditory and haptic sensory modalities. A fusion interface is a multi-sensory virtually-augmented synthetic environment. A new facility has been developed within the Human Engineering Division of the Armstrong Laboratory dedicated to exploratory development of fusion-interface concepts. One of the virtual concepts to be investigated in the Fusion Interfaces for Tactical Environments facility (FITE) is the application of EEG and other physiological measures for virtual control of functions within the flight environment. FITE is a specialized flight simulator which allows efficient concept development through the use of rapid prototyping followed by direct experience of new fusion concepts. The FITE facility also supports evaluation of fusion concepts by operational fighter pilots in a high fidelity simulated air combat environment. The facility was utilized by a multi-disciplinary team composed of operational pilots, human-factors engineers, electronics engineers, computer scientists, and experimental psychologists to prototype and evaluate the first multi-sensory, virtually-augmented cockpit. The cockpit employed LCD-based head-down displays, a helmet-mounted display, three-dimensionally localized audio displays, and a haptic display. This paper will endeavor to describe the FITE facility architecture, some of the characteristics of the FITE virtual display and control devices, and the potential application of EEG and other physiological measures within the FITE facility.

Ensemble simulations of inertial confinement fusion implosions

DOE PAGES

Nora, Ryan; Peterson, Jayson Luc; Spears, Brian Keith; ...

2017-05-24

The achievement of inertial confinement fusion ignition on the National Ignition Facility relies on the collection and interpretation of a limited (and expensive) set of experimental data. These data are therefore supplemented with state-of-the-art multi-dimensional radiation-hydrodynamic simulations to provide a better understanding of implosion dynamics and behavior. We present a relatively large number (~4000) of systematically perturbed 2D simulations to probe our understanding of low-mode fuel and ablator asymmetries seeded by asymmetric illumination. We find that Gaussian process surrogate models are able to predict both the total neutron yield and the degradation in performance due to asymmetries. Furthermore, the surrogatesmore » are then applied to simulations containing new sources of degradation to quantify the impact of the new source.« less

Conversion of NIMROD simulation results for graphical analysis using VisIt

DOE Office of Scientific and Technical Information (OSTI.GOV)

Romero-Talamas, C A

Software routines developed to prepare NIMROD [C. R. Sovinec et al., J. Comp. Phys. 195, 355 (2004)] results for three-dimensional visualization from simulations of the Sustained Spheromak Physics Experiment (SSPX ) [E. B. Hooper et al., Nucl. Fusion 39, 863 (1999)] are presented here. The visualization is done by first converting the NIMROD output to a format known as legacy VTK and then loading it to VisIt, a graphical analysis tool that includes three-dimensional rendering and various mathematical operations for large data sets. Sample images obtained from the processing of NIMROD data with VisIt are included.

[Application of 3D virtual reality technology with multi-modality fusion in resection of glioma located in central sulcus region].

PubMed

Chen, T N; Yin, X T; Li, X G; Zhao, J; Wang, L; Mu, N; Ma, K; Huo, K; Liu, D; Gao, B Y; Feng, H; Li, F

2018-05-08

Objective: To explore the clinical and teaching application value of virtual reality technology in preoperative planning and intraoperative guide of glioma located in central sulcus region. Method: Ten patients with glioma in the central sulcus region were proposed to surgical treatment. The neuro-imaging data, including CT, CTA, DSA, MRI, fMRI were input to 3dgo sczhry workstation for image fusion and 3D reconstruction. Spatial relationships between the lesions and the surrounding structures on the virtual reality image were obtained. These images were applied to the operative approach design, operation process simulation, intraoperative auxiliary decision and the training of specialist physician. Results: Intraoperative founding of 10 patients were highly consistent with preoperative simulation with virtual reality technology. Preoperative 3D reconstruction virtual reality images improved the feasibility of operation planning and operation accuracy. This technology had not only shown the advantages for neurological function protection and lesion resection during surgery, but also improved the training efficiency and effectiveness of dedicated physician by turning the abstract comprehension to virtual reality. Conclusion: Image fusion and 3D reconstruction based virtual reality technology in glioma resection is helpful for formulating the operation plan, improving the operation safety, increasing the total resection rate, and facilitating the teaching and training of the specialist physician.

A coupled-oscillator model with a conservation law for the rhythmic amoeboid movements of plasmodial slime molds

NASA Astrophysics Data System (ADS)

Tero, A.; Kobayashi, R.; Nakagaki, T.

2005-06-01

Experiments on the fusion and partial separation of plasmodia of the true slime mold Physarum polycephalum are described, concentrating on the spatio-temporal phase patterns of rhythmic amoeboid movement. On the basis of these experimental results we introduce a new model of coupled oscillators with one conserved quantity. Simulations using the model equations reproduce the experimental results well.

Computational modeling and analysis for left ventricle motion using CT/Echo image fusion

NASA Astrophysics Data System (ADS)

Kim, Ji-Yeon; Kang, Nahyup; Lee, Hyoung-Euk; Kim, James D. K.

2014-03-01

In order to diagnose heart disease such as myocardial infarction, 2D strain through the speckle tracking echocardiography (STE) or the tagged MRI is often used. However out-of-plane strain measurement using STE or tagged MRI is inaccurate. Therefore, strain for whole organ which are analyzed by simulation of 3D cardiac model can be applied in clinical diagnosis. To simulate cardiac contraction in a cycle, cardiac physical properties should be reflected in cardiac model. The myocardial wall in left ventricle is represented as a transversely orthotropic hyperelastic material, with the fiber orientation varying sequentially from the epicardial surface, through about 0° at the midwall, to the endocardial surface. A time-varying elastance model is simulated to contract myocardial fiber, and physiological intraventricular systolic pressure curves are employed for the cardiac dynamics simulation in a cycle. And an exact description of the cardiac motion should be acquired in order that essential boundary conditions for cardiac simulation are obtained effectively. Real time cardiac motion can be acquired by using echocardiography and exact cardiac geometrical 3D model can be reconstructed using 3D CT data. In this research, image fusion technology from CT and echocardiography is employed in order to consider patient-specific left ventricle movement. Finally, longitudinal strain from speckle tracking echocardiography which is known to fit actual left ventricle deformation relatively well is used to verify these results.

Instability growth for magnetized liner inertial fusion seeded by electro-thermal, electro-choric, and material strength effects

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pecover, J. D.; Chittenden, J. P.

A critical limitation of magnetically imploded systems such as magnetized liner inertial fusion (MagLIF) [Slutz et al., Phys. Plasmas 17, 056303 (2010)] is the magneto-Rayleigh-Taylor (MRT) instability which primarily disrupts the outer surface of the liner. MagLIF-relevant experiments have showed large amplitude multi-mode MRT instability growth growing from surface roughness [McBride et al., Phys. Rev. Lett. 109, 135004 (2012)], which is only reproduced by 3D simulations using our MHD code Gorgon when an artificially azimuthally correlated initialisation is added. We have shown that the missing azimuthal correlation could be provided by a combination of the electro-thermal instability (ETI) and anmore » “electro-choric” instability (ECI); describing, respectively, the tendency of current to correlate azimuthally early in time due to temperature dependent Ohmic heating; and an amplification of the ETI driven by density dependent resistivity around vapourisation. We developed and implemented a material strength model in Gorgon to improve simulation of the solid phase of liner implosions which, when applied to simulations exhibiting the ETI and ECI, gave a significant increase in wavelength and amplitude. Full circumference simulations of the MRT instability provided a significant improvement on previous randomly initialised results and approached agreement with experiment.« less

Molecular dynamics simulations of interactions between hydrogen and fusion-relevant materials

NASA Astrophysics Data System (ADS)

de Rooij, E. D.

2010-02-01

In a thermonuclear reactor fusion between hydrogen isotopes takes place, producing helium and energy. The so-called divertor is the part of the fusion reactor vessel where the plasma is neutralized in order to exhaust the helium. The surface plates of the divertor are subjected to high heat loads and high fluxes of energetic hydrogen and helium. In the next generation fusion device - the tokamak ITER - the expected conditions at the plates are particle fluxes exceeding 1e24 per second and square metre, particle energies ranging from 1 to 100 eV and an average heat load of 10 MW per square metre. Two materials have been identified as candidates for the ITER divertor plates: carbon and tungsten. Since there are currently no fusion devices that can create these harsh conditions, it is unknown how the materials will behave in terms of erosion and hydrogen retention. To gain more insight in the physical processes under these conditions molecular dynamics simulations have been conducted. Since diamond has been proposed as possible plasma facing material, we have studied erosion and hydrogen retention in diamond and amorphous hydrogenated carbon (a-C:H). As in experiments, diamond shows a lower erosion yield than a-C:H, however the hydrogen retention in diamond is much larger than in a-C:H and also hardly depending on the substrate temperature. This implies that simple heating of the surface is not sufficient to retrieve the hydrogen from diamond material, whereas a-C:H readily releases the retained hydrogen. So, in spite of the higher erosion yield carbon material other than diamond seems more suitable. Experiments suggest that the erosion yield of carbon material decreases with increasing flux. This was studied in our simulations. The results show no flux dependency, suggesting that the observed reduction is not a material property but is caused by external factors as, for example, redeposition of the erosion products. Our study of the redeposition showed that the sticking probability of small hydrocarbons is highest on material previously subjected to the highest hydrogen flux. This result suggests that redeposition is more effective under high than under low hydrogen fluxes, partly explaining the experimentally observed reduction in the carbon erosion yield. Lastly, we studied amorphous tungsten carbide. Amorphous material with three different carbon percentages (15, 50 and 95%) was subjected to deuterium bombardment and the resulting erosion and deuterium retention was analysed. The 95% carbon sample behaves like doped carbon, the carbon erosion yield is reduced and no tungsten is eroded. Segregation of the materials was observed, resulting in an accumulation of tungsten at the surface. The hydrogen retention was similar to a-C:H. The 15% carbon sample showed no significant erosion or retention. The most interesting was the 50% sample. Here deuterium bubbles formed that burst open after sufficiently long bombardment, thereby removing both carbon and tungsten from the surface. In the context of ITER our MD simulations suggest that tungsten is the better suited material since both the erosion and the hydrogen retention are significantly lower than for carbon.

Fusion information entropy method of rolling bearing fault diagnosis based on n-dimensional characteristic parameter distance

NASA Astrophysics Data System (ADS)

Ai, Yan-Ting; Guan, Jiao-Yue; Fei, Cheng-Wei; Tian, Jing; Zhang, Feng-Ling

2017-05-01

To monitor rolling bearing operating status with casings in real time efficiently and accurately, a fusion method based on n-dimensional characteristic parameters distance (n-DCPD) was proposed for rolling bearing fault diagnosis with two types of signals including vibration signal and acoustic emission signals. The n-DCPD was investigated based on four information entropies (singular spectrum entropy in time domain, power spectrum entropy in frequency domain, wavelet space characteristic spectrum entropy and wavelet energy spectrum entropy in time-frequency domain) and the basic thought of fusion information entropy fault diagnosis method with n-DCPD was given. Through rotor simulation test rig, the vibration and acoustic emission signals of six rolling bearing faults (ball fault, inner race fault, outer race fault, inner-ball faults, inner-outer faults and normal) are collected under different operation conditions with the emphasis on the rotation speed from 800 rpm to 2000 rpm. In the light of the proposed fusion information entropy method with n-DCPD, the diagnosis of rolling bearing faults was completed. The fault diagnosis results show that the fusion entropy method holds high precision in the recognition of rolling bearing faults. The efforts of this study provide a novel and useful methodology for the fault diagnosis of an aeroengine rolling bearing.

The potential of imposed magnetic fields for enhancing ignition probability and fusion energy yield in indirect-drive inertial confinement fusion

NASA Astrophysics Data System (ADS)

Perkins, L. J.; Ho, D. D.-M.; Logan, B. G.; Zimmerman, G. B.; Rhodes, M. A.; Strozzi, D. J.; Blackfield, D. T.; Hawkins, S. A.

2017-06-01

We examine the potential that imposed magnetic fields of tens of Tesla that increase to greater than 10 kT (100 MGauss) under implosion compression may relax the conditions required for ignition and propagating burn in indirect-drive inertial confinement fusion (ICF) targets. This may allow the attainment of ignition, or at least significant fusion energy yields, in presently performing ICF targets on the National Ignition Facility (NIF) that today are sub-marginal for thermonuclear burn through adverse hydrodynamic conditions at stagnation [Doeppner et al., Phys. Rev. Lett. 115, 055001 (2015)]. Results of detailed two-dimensional radiation-hydrodynamic-burn simulations applied to NIF capsule implosions with low-mode shape perturbations and residual kinetic energy loss indicate that such compressed fields may increase the probability for ignition through range reduction of fusion alpha particles, suppression of electron heat conduction, and potential stabilization of higher-mode Rayleigh-Taylor instabilities. Optimum initial applied fields are found to be around 50 T. Given that the full plasma structure at capsule stagnation may be governed by three-dimensional resistive magneto-hydrodynamics, the formation of closed magnetic field lines might further augment ignition prospects. Experiments are now required to further assess the potential of applied magnetic fields to ICF ignition and burn on NIF.

Staggered scheduling of sensor estimation and fusion for tracking over long-haul links

DOE PAGES

Liu, Qiang; Rao, Nageswara S. V.; Wang, Xin

2016-08-01

Networked sensing can be found in a multitude of real-world applications. Here, we focus on the communication-and computation-constrained long-haul sensor networks, where sensors are remotely deployed over a vast geographical area to perform certain tasks. Of special interest is a class of such networks where sensors take measurements of one or more dynamic targets and send their state estimates to a remote fusion center via long-haul satellite links. The severe loss and delay over such links can easily reduce the amount of sensor data received by the fusion center, thereby limiting the potential information fusion gain and resulting in suboptimalmore » tracking performance. In this paper, starting with the temporal-domain staggered estimation for an individual sensor, we explore the impact of the so-called intra-state prediction and retrodiction on estimation errors. We then investigate the effect of such estimation scheduling across different sensors on the spatial-domain fusion performance, where the sensing time epochs across sensors are scheduled in an asynchronous and staggered manner. In particular, the impact of communication delay and loss as well as sensor bias on such scheduling is explored by means of numerical and simulation studies that demonstrate the validity of our analysis.« less

Sensor data fusion of radar, ESM, IFF, and data LINK of the Canadian Patrol Frigate and the data alignment issues

NASA Astrophysics Data System (ADS)

Couture, Jean; Boily, Edouard; Simard, Marc-Alain

1996-05-01

The research and development group at Loral Canada is now at the second phase of the development of a data fusion demonstration model (DFDM) for a naval anti-air warfare to be used as a workbench tool to perform exploratory research. This project has emphatically addressed how the concepts related to fusion could be implemented within the Canadian Patrol Frigate (CPF) software environment. The project has been designed to read data passively on the CPF bus without any modification to the CPF software. This has brought to light important time alignment issues since the CPF sensors and the CPF command and control system were not important time alignment issues since the CPF sensors and the CPF command and control system were not originally designed to support a track management function which fuses information. The fusion of data from non-organic sensors with the tactical Link-11 data has produced stimulating spatial alignment problems which have been overcome by the use of a geodetic referencing coordinate system. Some benchmark scenarios have been selected to quantitatively demonstrate the capabilities of this fusion implementation. This paper describes the implementation design of DFDM (version 2), and summarizes the results obtained so far when fusing the scenarios simulated data.

Models of lipid droplets growth and fission in adipocyte cells

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boschi, Federico, E-mail: federico.boschi@univr.it; Rizzatti, Vanni; Zamboni, Mauro

Lipid droplets (LD) are spherical cellular inclusion devoted to lipids storage. It is well known that excessive accumulation of lipids leads to several human worldwide diseases like obesity, type 2 diabetes, hepatic steatosis and atherosclerosis. LDs' size range from fraction to one hundred of micrometers in adipocytes and is related to the lipid content, but their growth is still a puzzling question. It has been suggested that LDs can grow in size due to the fusion process by which a larger LD is obtained by the merging of two smaller LDs, but these events seems to be rare and difficultmore » to be observed. Many other processes are thought to be involved in the number and growth of LDs, like the de novo formation and the growth through additional neutral lipid deposition in pre-existing droplets. Moreover the number and size of LDs are influenced by the catabolism and the absorption or interaction with other organelles. The comprehension of these processes could help in the confinement of the pathologies related to lipid accumulation. In this study the LDs' size distribution, number and the total volume of immature (n=12), mature (n=12, 10-days differentiated) and lipolytic (n=12) 3T3-L1 adipocytes were considered. More than 11,000 LDs were measured in the 36 cells after Oil Red O staining. In a previous work Monte Carlo simulations were used to mimic the fusion process alone between LDs. We found that, considering the fusion as the only process acting on the LDs, the size distribution in mature adipocytes can be obtained with numerical simulation starting from the size distribution in immature cells provided a very high rate of fusion events. In this paper Monte Carlo simulations were developed to mimic the interaction between LDs taking into account many other processes in addition to fusion (de novo formation and the growth through additional neutral lipid deposition in pre-existing droplets) in order to reproduce the LDs growth and we also simulated the catabolism (fission and the decrease through neutral lipid exit from pre-existing droplets) to reproduce their size reduction observed in lipolytic conditions. The results suggest that each single process, considered alone, can not be considered the only responsible for the size variation observed, but more than one of them, playing together, can quite well reproduce the experimental data. - Highlights: The growth and fission of the lipid droplets (LDs) were computationally simulated. To write and test the growth and fission models more than 110,000 LDs were measured. The usual processes considered alone, are not able to justify the experimental data. Some processes, playing together, can explain the growth and fission.« less

Multi-Sensor Fusion with Interaction Multiple Model and Chi-Square Test Tolerant Filter.

PubMed

Yang, Chun; Mohammadi, Arash; Chen, Qing-Wei

2016-11-02

Motivated by the key importance of multi-sensor information fusion algorithms in the state-of-the-art integrated navigation systems due to recent advancements in sensor technologies, telecommunication, and navigation systems, the paper proposes an improved and innovative fault-tolerant fusion framework. An integrated navigation system is considered consisting of four sensory sub-systems, i.e., Strap-down Inertial Navigation System (SINS), Global Navigation System (GPS), the Bei-Dou2 (BD2) and Celestial Navigation System (CNS) navigation sensors. In such multi-sensor applications, on the one hand, the design of an efficient fusion methodology is extremely constrained specially when no information regarding the system's error characteristics is available. On the other hand, the development of an accurate fault detection and integrity monitoring solution is both challenging and critical. The paper addresses the sensitivity issues of conventional fault detection solutions and the unavailability of a precisely known system model by jointly designing fault detection and information fusion algorithms. In particular, by using ideas from Interacting Multiple Model (IMM) filters, the uncertainty of the system will be adjusted adaptively by model probabilities and using the proposed fuzzy-based fusion framework. The paper also addresses the problem of using corrupted measurements for fault detection purposes by designing a two state propagator chi-square test jointly with the fusion algorithm. Two IMM predictors, running in parallel, are used and alternatively reactivated based on the received information form the fusion filter to increase the reliability and accuracy of the proposed detection solution. With the combination of the IMM and the proposed fusion method, we increase the failure sensitivity of the detection system and, thereby, significantly increase the overall reliability and accuracy of the integrated navigation system. Simulation results indicate that the proposed fault tolerant fusion framework provides superior performance over its traditional counterparts.

Biomechanical Analysis of Cervical Disc Replacement and Fusion Using Single Level, Two Level, and Hybrid Constructs.

PubMed

Gandhi, Anup A; Kode, Swathi; DeVries, Nicole A; Grosland, Nicole M; Smucker, Joseph D; Fredericks, Douglas C

2015-10-15

A biomechanical study comparing arthroplasty with fusion using human cadaveric C2-T1 spines. To compare the kinematics of the cervical spine after arthroplasty and fusion using single level, 2 level and hybrid constructs. Previous studies have shown that spinal levels adjacent to a fusion experience increased motion and higher stress which may lead to adjacent segment disc degeneration. Cervical arthroplasty achieves similar decompression but preserves the motion at the operated level, potentially decreasing the occurrence of adjacent segment disc degeneration. 11 specimens (C2-T1) were divided into 2 groups (BRYAN and PRESTIGE LP). The specimens were tested in the following order; intact, single level total disc replacement (TDR) at C5-C6, 2-level TDR at C5-C6-C7, fusion at C5-C6 and TDR at C6-C7 (Hybrid construct), and lastly a 2-level fusion. The intact specimens were tested up to a moment of 2.0 Nm. After each surgical intervention, the specimens were loaded until the primary motion (C2-T1) matched the motion of the respective intact state (hybrid control). An arthroplasty preserved motion at the implanted level and maintained normal motion at the nonoperative levels. Arthrodesis resulted in a significant decrease in motion at the fused level and an increase in motion at the unfused levels. In the hybrid construct, the TDR adjacent to fusion preserved motion at the arthroplasty level, thereby reducing the demand on the other levels. Cervical disc arthroplasty with both the BRYAN and PRESTIGE LP discs not only preserved the motion at the operated level, but also maintained the normal motion at the adjacent levels. Under simulated physiologic loading, the motion patterns of the spine with the BRYAN or PRESTIGE LP disc were very similar and were closer than fusion to the intact motion pattern. An adjacent segment disc replacement is biomechanically favorable to a fusion in the presence of a pre-existing fusion.

Multi-Sensor Fusion with Interaction Multiple Model and Chi-Square Test Tolerant Filter

PubMed Central

Yang, Chun; Mohammadi, Arash; Chen, Qing-Wei

2016-01-01

Motivated by the key importance of multi-sensor information fusion algorithms in the state-of-the-art integrated navigation systems due to recent advancements in sensor technologies, telecommunication, and navigation systems, the paper proposes an improved and innovative fault-tolerant fusion framework. An integrated navigation system is considered consisting of four sensory sub-systems, i.e., Strap-down Inertial Navigation System (SINS), Global Navigation System (GPS), the Bei-Dou2 (BD2) and Celestial Navigation System (CNS) navigation sensors. In such multi-sensor applications, on the one hand, the design of an efficient fusion methodology is extremely constrained specially when no information regarding the system’s error characteristics is available. On the other hand, the development of an accurate fault detection and integrity monitoring solution is both challenging and critical. The paper addresses the sensitivity issues of conventional fault detection solutions and the unavailability of a precisely known system model by jointly designing fault detection and information fusion algorithms. In particular, by using ideas from Interacting Multiple Model (IMM) filters, the uncertainty of the system will be adjusted adaptively by model probabilities and using the proposed fuzzy-based fusion framework. The paper also addresses the problem of using corrupted measurements for fault detection purposes by designing a two state propagator chi-square test jointly with the fusion algorithm. Two IMM predictors, running in parallel, are used and alternatively reactivated based on the received information form the fusion filter to increase the reliability and accuracy of the proposed detection solution. With the combination of the IMM and the proposed fusion method, we increase the failure sensitivity of the detection system and, thereby, significantly increase the overall reliability and accuracy of the integrated navigation system. Simulation results indicate that the proposed fault tolerant fusion framework provides superior performance over its traditional counterparts. PMID:27827832

Multi-Fluid Simulations of Field Reversed Configuration Formation

NASA Astrophysics Data System (ADS)

Sousa, Eder; Martin, Robert

2017-10-01

The use of field reversed configuration (FRC) have been studied extensively for fusion application but here we investigate them for propulsion purposes. FRCs have the potential to produce highly variable thrust and specific impulse using different gases as propellant. Aspects of the FRC formation physics, using a rotating magnetic field (RMF) at low power, are simulated using a multi-fluid plasma model. Results are compared with experimental observations with emphasis in the development of instabilities and robustness of the field reversal. The use of collisional radiative models are used to help compare experiment versus simulation results. Distribution A: Approved for public release; distribution unlimited; Clearance No. 17445. This work is supported by the Air Force Office of Scientific Research Grant Number 17RQCOR465.

An FPGA-based heterogeneous image fusion system design method

NASA Astrophysics Data System (ADS)

Song, Le; Lin, Yu-chi; Chen, Yan-hua; Zhao, Mei-rong

2011-08-01

Taking the advantages of FPGA's low cost and compact structure, an FPGA-based heterogeneous image fusion platform is established in this study. Altera's Cyclone IV series FPGA is adopted as the core processor of the platform, and the visible light CCD camera and infrared thermal imager are used as the image-capturing device in order to obtain dualchannel heterogeneous video images. Tailor-made image fusion algorithms such as gray-scale weighted averaging, maximum selection and minimum selection methods are analyzed and compared. VHDL language and the synchronous design method are utilized to perform a reliable RTL-level description. Altera's Quartus II 9.0 software is applied to simulate and implement the algorithm modules. The contrast experiments of various fusion algorithms show that, preferably image quality of the heterogeneous image fusion can be obtained on top of the proposed system. The applied range of the different fusion algorithms is also discussed.

Inertial fusion program. Progress report, January 1-June 30, 1978

DOE Office of Scientific and Technical Information (OSTI.GOV)

Skoberne, F.

1980-05-01

Studies and experiments aimed at investigating the possibility of restoring wavefront quality in optical systems through phase conjugation are summarized, and work that could lead to the development of highly damage-resistant isolators is discussed. The effects of various parameters on pulse-energy uniformity and of multipass extraction on laser efficiency are reported. Results of equation-of-state, shock propagation, multiburst simulation, and opacity measurements are discussed. Target designs are described that should provide a smooth transition from the exploding-pusher regime of experiments to that of isentropic compression. Progress in target fabrication techniques toward creating a 20-times-liquid-density target are outlined, and efforts that ledmore » to the extension of our neutron detection capability to levels of less than 10/sup 3/ n are summarized. The results of various studies of laser fusion application, e.g., for producing ultrahigh-temperature process heat or hydrogen from water decomposition are presented, as well as investigations of fusion-fission hybrids for the production of /sup 233/U from /sup 232/Th.« less

Passive tracking scheme for a single stationary observer

NASA Astrophysics Data System (ADS)

Chan, Y. T.; Rea, Terry

2001-08-01

While there are many techniques for Bearings-Only Tracking (BOT) in the ocean environment, they do not apply directly to the land situation. Generally, for tactical reasons, the land observer platform is stationary; but, it has two sensors, visual and infrared, for measuring bearings and a laser range finder (LRF) for measuring range. There is a requirement to develop a new BOT data fusion scheme that fuses the two sets of bearing readings, and together with a single LRF measurement, produces a unique track. This paper first develops a parameterized solution for the target speeds, prior to the occurrence of the LRF measurement, when the problem is unobservable. At, and after, the LRF measurement, a BOT formulated as a least squares (LS) estimator then produces a unique LS estimate of the target states. Bearing readings from the other sensor serve as instrumental variables in a data fusion setting to eliminate the bias in the BOT estimator. The result is recursive, unbiased and decentralized data fusion scheme. Results from two simulation experiments have corroborated the theoretical development and show that the scheme is optimal.

A D-D/D-T fusion reaction based neutron generator system for liver tumor BNCT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Koivunoro, H.; Lou, T.P.; Leung, K. N.

2003-04-02

Boron-neutron capture therapy (BNCT) is an experimental radiation treatment modality used for highly malignant tumor treatments. Prior to irradiation with low energetic neutrons, a 10B compound is located selectively in the tumor cells. The effect of the treatment is based on the high LET radiation released in the {sup 10}B(n,{alpha}){sup 7}Li reaction with thermal neutrons. BNCT has been used experimentally for brain tumor and melanoma treatments. Lately applications of other severe tumor type treatments have been introduced. Results have shown that liver tumors can also be treated by BNCT. At Lawrence Berkeley National Laboratory, various compact neutron generators based onmore » D-D or D-T fusion reactions are being developed. The earlier theoretical studies of the D-D or D-T fusion reaction based neutron generators have shown that the optimal moderator and reflector configuration for brain tumor BNCT can be created. In this work, the applicability of 2.5 MeV neutrons for liver tumor BNCT application was studied. The optimal neutron energy for external liver treatments is not known. Neutron beams of different energies (1eV < E < 100 keV) were simulated and the dose distribution in the liver was calculated with the MCNP simulation code. In order to obtain the optimal neutron energy spectrum with the D-D neutrons, various moderator designs were performed using MCNP simulations. In this article the neutron spectrum and the optimized beam shaping assembly for liver tumor treatments is presented.« less

Toward a first-principles integrated simulation of tokamak edge plasmas

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chang, C S; Klasky, Scott A; Cummings, Julian

2008-01-01

Performance of the ITER is anticipated to be highly sensitive to the edge plasma condition. The edge pedestal in ITER needs to be predicted from an integrated simulation of the necessary firstprinciples, multi-scale physics codes. The mission of the SciDAC Fusion Simulation Project (FSP) Prototype Center for Plasma Edge Simulation (CPES) is to deliver such a code integration framework by (1) building new kinetic codes XGC0 and XGC1, which can simulate the edge pedestal buildup; (2) using and improving the existing MHD codes ELITE, M3D-OMP, M3D-MPP and NIMROD, for study of large-scale edge instabilities called Edge Localized Modes (ELMs); andmore » (3) integrating the codes into a framework using cutting-edge computer science technology. Collaborative effort among physics, computer science, and applied mathematics within CPES has created the first working version of the End-to-end Framework for Fusion Integrated Simulation (EFFIS), which can be used to study the pedestal-ELM cycles.« less

First ERO2.0 modeling of Be erosion and non-local transport in JET ITER-like wall

NASA Astrophysics Data System (ADS)

Romazanov, J.; Borodin, D.; Kirschner, A.; Brezinsek, S.; Silburn, S.; Huber, A.; Huber, V.; Bufferand, H.; Firdaouss, M.; Brömmel, D.; Steinbusch, B.; Gibbon, P.; Lasa, A.; Borodkina, I.; Eksaeva, A.; Linsmeier, Ch; Contributors, JET

2017-12-01

ERO is a Monte-Carlo code for modeling plasma-wall interaction and 3D plasma impurity transport for applications in fusion research. The code has undergone a significant upgrade (ERO2.0) which allows increasing the simulation volume in order to cover the entire plasma edge of a fusion device, allowing a more self-consistent treatment of impurity transport and comparison with a larger number and variety of experimental diagnostics. In this contribution, the physics-relevant technical innovations of the new code version are described and discussed. The new capabilities of the code are demonstrated by modeling of beryllium (Be) erosion of the main wall during JET limiter discharges. Results for erosion patterns along the limiter surfaces and global Be transport including incident particle distributions are presented. A novel synthetic diagnostic, which mimics experimental wide-angle 2D camera images, is presented and used for validating various aspects of the code, including erosion, magnetic shadowing, non-local impurity transport, and light emission simulation.

Simulation and design of feedback control on resistive wall modes in Keda Torus eXperiment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, Chenguang; Liu, Wandong; Li, Hong

2014-12-15

The feedback control of resistive wall modes (RWMs) in Keda Torus eXperiment (KTX) (Liu et al., Plasma Phys. Controlled Fusion 56, 094009 (2014)) is investigated by simulation. A linear model is built to describe the growth of the unstable modes in the absence of feedback and the resulting mode suppression due to feedback, given the typical reversed field pinch plasma equilibrium. The layout of KTX with two shell structures (the vacuum vessel and the stabilizing shell) is taken into account. The feedback performance is explored both in the scheme of “clean mode control” (Zanca et al., Nucl. Fusion 47, 1425more » (2007)) and “raw mode control.” The discrete time control model with specific characteristic times will mimic the real feedback control action and lead to the favored control cycle. Moreover, the conceptual design of feedback control system is also presented, targeting on both RWMs and tearing modes.« less

Final Technical Report: Collaborative Research Center for Nonlinear Simulation of Energetic Particles

DOE Office of Scientific and Technical Information (OSTI.GOV)

Berk, Herbert L.

2018-02-15

The study of this project focused on developing a reduced nonlinear model to describe chirping processes in a fusion plasma. A successful method was developed with results clear enough to allow an analytic theory to be developed that replicates the long term response of a nonlinear phase space structure immersed in the MHD continnuum.

Single crystal diamond detector measurements of deuterium-deuterium and deuterium-tritium neutrons in Joint European Torus fusion plasmas.

PubMed

Cazzaniga, C; Sundén, E Andersson; Binda, F; Croci, G; Ericsson, G; Giacomelli, L; Gorini, G; Griesmayer, E; Grosso, G; Kaveney, G; Nocente, M; Perelli Cippo, E; Rebai, M; Syme, B; Tardocchi, M

2014-04-01

First simultaneous measurements of deuterium-deuterium (DD) and deuterium-tritium neutrons from deuterium plasmas using a Single crystal Diamond Detector are presented in this paper. The measurements were performed at JET with a dedicated electronic chain that combined high count rate capabilities and high energy resolution. The deposited energy spectrum from DD neutrons was successfully reproduced by means of Monte Carlo calculations of the detector response function and simulations of neutron emission from the plasma, including background contributions. The reported results are of relevance for the development of compact neutron detectors with spectroscopy capabilities for installation in camera systems of present and future high power fusion experiments.

Quantifying Fusion Born Ion Populations in Magnetically Confined Plasmas using Ion Cyclotron Emission

DOE PAGES

Carbajal, L.; Warwick Univ., Coventry; Dendy, R. O.; ...

2017-03-07

Ion cyclotron emission (ICE) offers unique promise as a diagnostic of the fusion born alpha-particle population in magnetically confined plasmas. Pioneering observations from JET and TFTR found that ICE intensity P ICE scales approximately linearly with the measured neutron flux from fusion reactions, and with the inferred concentration, n /n i , of fusion-born alpha-particles confined within the plasma. We present fully nonlinear self-consistent kinetic simulations that reproduce this scaling for the first time. This resolves a longstanding question in the physics of fusion alpha particle confinement and stability in MCF plasmas. It confirms the MCI as the likely emissionmore » mechanism and greatly strengthens the basis for diagnostic exploitation of ICE in future burning plasmas.« less

Simulation of the target creation through FRC merging for a magneto-inertial fusion concept

NASA Astrophysics Data System (ADS)

Li, Chenguang; Yang, Xianjun

2017-04-01

A two-dimensional magnetohydrodynamics model has been used to simulate the target creation process in a magneto-inertial fusion concept named Magnetized Plasma Fusion Reactor (MPFR) [C. Li and X. Yang, Phys. Plasmas 23, 102702 (2016)], where the target plasma created through Field reversed configuration (FRC) merging was compressed by an imploding liner driven by the pulsed-power driver. In the scheme, two initial FRCs (Field reversed configurations) are translated into the region where FRC merging occurs, bringing out the target plasma ready for compression. The simulations cover the three stages of the target creation process: formation, translation, and merging. The factors affecting the achieved target are analyzed numerically. The magnetic field gradient produced by the conical coils is found to determine how fast the FRC is accelerated to peak velocity and the collision merging occurs. Moreover, it is demonstrated that FRC merging can be realized by real coils with gaps showing nearly identical performance, and the optimized target by FRC merging shows larger internal energy and retained flux, which is more suitable for the MPFR concept.

Sputtering, Plasma Chemistry, and RF Sheath Effects in Low-Temperature and Fusion Plasma Modeling

NASA Astrophysics Data System (ADS)

Jenkins, Thomas G.; Kruger, Scott E.; McGugan, James M.; Pankin, Alexei Y.; Roark, Christine M.; Smithe, David N.; Stoltz, Peter H.

2016-09-01

A new sheath boundary condition has been implemented in VSim, a plasma modeling code which makes use of both PIC/MCC and fluid FDTD representations. It enables physics effects associated with DC and RF sheath formation - local sheath potential evolution, heat/particle fluxes, and sputtering effects on complex plasma-facing components - to be included in macroscopic-scale plasma simulations that need not resolve sheath scale lengths. We model these effects in typical ICRF antenna operation scenarios on the Alcator C-Mod fusion device, and present comparisons of our simulation results with experimental data together with detailed 3D animations of antenna operation. Complex low-temperature plasma chemistry modeling in VSim is facilitated by MUNCHKIN, a standalone python/C++/SQL code that identifies possible reaction paths for a given set of input species, solves 1D rate equations for the ensuing system's chemical evolution, and generates VSim input blocks with appropriate cross-sections/reaction rates. These features, as well as principal path analysis (to reduce the number of simulated chemical reactions while retaining accuracy) and reaction rate calculations from user-specified distribution functions, will also be demonstrated. Supported by the U.S. Department of Energy's SBIR program, Award DE-SC0009501.

Generation of the neutron response function of an NE213 scintillator for fusion applications

NASA Astrophysics Data System (ADS)

Binda, F.; Eriksson, J.; Ericsson, G.; Hellesen, C.; Conroy, S.; Nocente, M.; Sundén, E. Andersson; JET Contributors

2017-09-01

In this work we present a method to evaluate the neutron response function of an NE213 liquid scintillator. This method is particularly useful when the proton light yield function of the detector has not been measured, since it is based on a proton light yield function taken from literature, MCNPX simulations, measurements of gamma-rays from a calibration source and measurements of neutrons from fusion experiments with ohmic plasmas. The inclusion of the latter improves the description of the proton light yield function in the energy range of interest (around 2.46 MeV). We apply this method to an NE213 detector installed at JET, inside the radiation shielding of the magnetic proton recoil (MPRu) spectrometer, and present the results from the calibration along with some examples of application of the response function to perform neutron emission spectroscopy (NES) of fusion plasmas. We also investigate how the choice of the proton light yield function affects the NES analysis, finding that the result does not change significantly. This points to the fact that the method for the evaluation of the neutron response function is robust and gives reliable results.

Efficiency and Accuracy in Thermal Simulation of Powder Bed Fusion of Bulk Metallic Glass

NASA Astrophysics Data System (ADS)

Lindwall, J.; Malmelöv, A.; Lundbäck, A.; Lindgren, L.-E.

2018-05-01

Additive manufacturing by powder bed fusion processes can be utilized to create bulk metallic glass as the process yields considerably high cooling rates. However, there is a risk that reheated material set in layers may become devitrified, i.e., crystallize. Therefore, it is advantageous to simulate the process to fully comprehend it and design it to avoid the aforementioned risk. However, a detailed simulation is computationally demanding. It is necessary to increase the computational speed while maintaining accuracy of the computed temperature field in critical regions. The current study evaluates a few approaches based on temporal reduction to achieve this. It is found that the evaluated approaches save a lot of time and accurately predict the temperature history.

Design of a multisensor data fusion system for target detection

NASA Astrophysics Data System (ADS)

Thomopoulos, Stelios C.; Okello, Nickens N.; Kadar, Ivan; Lovas, Louis A.

1993-09-01

The objective of this paper is to discuss the issues that are involved in the design of a multisensor fusion system and provide a systematic analysis and synthesis methodology for the design of the fusion system. The system under consideration consists of multifrequency (similar) radar sensors. However, the fusion design must be flexible to accommodate additional dissimilar sensors such as IR, EO, ESM, and Ladar. The motivation for the system design is the proof of the fusion concept for enhancing the detectability of small targets in clutter. In the context of down-selecting the proper configuration for multisensor (similar and dissimilar, and centralized vs. distributed) data fusion, the issues of data modeling, fusion approaches, and fusion architectures need to be addressed for the particular application being considered. Although the study of different approaches may proceed in parallel, the interplay among them is crucial in selecting a fusion configuration for a given application. The natural sequence for addressing the three different issues is to begin from the data modeling, in order to determine the information content of the data. This information will dictate the appropriate fusion approach. This, in turn, will lead to a global fusion architecture. Both distributed and centralized fusion architectures are used to illustrate the design issues along with Monte-Carlo simulation performance comparison of a single sensor versus a multisensor centrally fused system.

High-resolution modeling of indirectly driven high-convergence layered inertial confinement fusion capsule implosions

DOE PAGES

Haines, Brian M.; Aldrich, C. H.; Campbell, J. M.; ...

2017-04-24

In this study, we present the results of high-resolution simulations of the implosion of high-convergence layered indirect-drive inertial confinement fusion capsules of the type fielded on the National Ignition Facility using the xRAGE radiation-hydrodynamics code. In order to evaluate the suitability of xRAGE to model such experiments, we benchmark simulation results against available experimental data, including shock-timing, shock-velocity, and shell trajectory data, as well as hydrodynamic instability growth rates. We discuss the code improvements that were necessary in order to achieve favorable comparisons with these data. Due to its use of adaptive mesh refinement and Eulerian hydrodynamics, xRAGE is particularlymore » well suited for high-resolution study of multi-scale engineering features such as the capsule support tent and fill tube, which are known to impact the performance of high-convergence capsule implosions. High-resolution two-dimensional (2D) simulations including accurate and well-resolved models for the capsule fill tube, support tent, drive asymmetry, and capsule surface roughness are presented. These asymmetry seeds are isolated in order to study their relative importance and the resolution of the simulations enables the observation of details that have not been previously reported. We analyze simulation results to determine how the different asymmetries affect hotspot reactivity, confinement, and confinement time and how these combine to degrade yield. Yield degradation associated with the tent occurs largely through decreased reactivity due to the escape of hot fuel mass from the hotspot. Drive asymmetries and the fill tube, however, degrade yield primarily via burn truncation, as associated instability growth accelerates the disassembly of the hotspot. Finally, modeling all of these asymmetries together in 2D leads to improved agreement with experiment but falls short of explaining the experimentally observed yield degradation, consistent with previous 2D simulations of such capsules.« less

High-Q plasmas in the TFTR tokamak

NASA Astrophysics Data System (ADS)

Jassby, D. L.; Barnes, C. W.; Bell, M. G.; Bitter, M.; Boivin, R.; Bretz, N. L.; Budny, R. V.; Bush, C. E.; Dylla, H. F.; Efthimion, P. C.; Fredrickson, E. D.; Hawryluk, R. J.; Hill, K. W.; Hosea, J.; Hsuan, H.; Janos, A. C.; Jobes, F. C.; Johnson, D. W.; Johnson, L. C.; Kamperschroer, J.; Kieras-Phillips, C.; Kilpatrick, S. J.; LaMarche, P. H.; LeBlanc, B.; Mansfield, D. K.; Marmar, E. S.; McCune, D. C.; McGuire, K. M.; Meade, D. M.; Medley, S. S.; Mikkelsen, D. R.; Mueller, D.; Owens, D. K.; Park, H. K.; Paul, S. F.; Pitcher, S.; Ramsey, A. T.; Redi, M. H.; Sabbagh, S. A.; Scott, S. D.; Snipes, J.; Stevens, J.; Strachan, J. D.; Stratton, B. C.; Synakowski, E. J.; Taylor, G.; Terry, J. L.; Timberlake, J. R.; Towner, H. H.; Ulrickson, M.; von Goeler, S.; Wieland, R. M.; Williams, M.; Wilson, J. R.; Wong, K.-L.; Young, K. M.; Zarnstorff, M. C.; Zweben, S. J.

1991-08-01

In the Tokamak Fusion Test Reactor (TFTR) [Plasma Phys. Controlled Fusion 26, 11 (1984)], the highest neutron source strength Sn and D-D fusion power gain QDD are realized in the neutral-beam-fueled and heated ``supershot'' regime that occurs after extensive wall conditioning to minimize recycling. For the best supershots, Sn increases approximately as P1.8b. The highest-Q shots are characterized by high Te (up to 12 keV), Ti (up to 34 keV), and stored energy (up to 4.7 MJ), highly peaked density profiles, broad Te profiles, and lower Zeff. Replacement of critical areas of the graphite limiter tiles with carbon-fiber composite tiles and improved alignment with the plasma have mitigated the ``carbon bloom.'' Wall conditioning by lithium pellet injection prior to the beam pulse reduces carbon influx and particle recycling. Empirically, QDD increases with decreasing pre-injection carbon radiation, and increases strongly with density peakedness [ne(0)/] during the beam pulse. To date, the best fusion results are Sn=5×1016 n/sec, QDD=1.85×10-3, and neutron yield=4.0×1016 n/pulse, obtained at Ip=1.6-1.9 MA and beam energy Eb=95-103 keV, with nearly balanced co- and counter-injected beam power. Computer simulations of supershot plasmas show that typically 50%-60% of Sn arises from beam-target reactions, with the remainder divided between beam-beam and thermonuclear reactions, the thermonuclear fraction increasing with Pb. The simulations predict that QDT=0.3-0.4 would be obtained for the best present plasma conditions, if half the deuterium neutral beams were to be replaced by tritium beams. Somewhat higher values are calculated if D beams are injected into a predominantly tritium target plasma. The projected central beta of fusion alphas is 0.4%-0.6%, a level sufficient for the study of alpha-induced collective effects.

Overview of Shipboard Data Fusion and Resource Management R&D Results and Rationale for Its Real-Time Implementation in the ASCACT Testbed

DTIC Science & Technology

1996-04-01

and IRST sensor simulations. More specifically, the CPF radars currently supported by the CASE_ATTI sensor module are the SG-150 Sea Giraffe and the...specifications. The current A WW sensor suite of the CPF comprises the SPS-49 long range 2-D radar, the Sea Giraffe medium range 2-D radar, the CANEWS ESM...Sea Giraffe . This represents an original novelty of our simulation environment. P435278.PDF [Page: 66 of 128] UNCLASSIFIED 50 The baseline

Diagnosing laser-preheated magnetized plasmas relevant to magnetized liner inertial fusion

DOE PAGES

Harvey-Thompson, Adam James; Sefkow, Adam B.; Nagayama, Taisuke N.; ...

2015-12-22

In this paper, we present a platform on the OMEGA EP Laser Facility that creates and diagnoses the conditions present during the preheat stage of the MAGnetized Liner Inertial Fusion (MagLIF) concept. Experiments were conducted using 9 kJ of 3ω (355 nm) light to heat an underdense deuterium gas (electron density: 2.5 × 10 20 cm -3 = 0.025 of critical density) magnetized with a 10 T axial field. Results show that the deuterium plasma reached a peak electron temperature of 670 ± 140 eV, diagnosed using streaked spectroscopy of an argon dopant. The results demonstrate that plasmas relevant tomore » the preheat stage of MagLIF can be produced at multiple laser facilities, thereby enabling more rapid progress in understanding magnetized preheat. Results are compared with magneto-radiation-hydrodynamics simulations, and plans for future experiments are described.« less

A Particle-in-Cell Simulation for the Traveling Wave Direct Energy Converter (TWDEC) for Fusion Propulsion

NASA Technical Reports Server (NTRS)

Chap, Andrew; Tarditi, Alfonso G.; Scott, John H.

2013-01-01

A Particle-in-cell simulation model has been developed to study the physics of the Traveling Wave Direct Energy Converter (TWDEC) applied to the conversion of charged fusion products into electricity. In this model the availability of a beam of collimated fusion products is assumed; the simulation is focused on the conversion of the beam kinetic energy into alternating current (AC) electric power. The model is electrostatic, as the electro-dynamics of the relatively slow ions can be treated in the quasistatic approximation. A two-dimensional, axisymmetric (radial-axial coordinates) geometry is considered. Ion beam particles are injected on one end and travel along the axis through ring-shaped electrodes with externally applied time-varying voltages, thus modulating the beam by forming a sinusoidal pattern in the beam density. Further downstream, the modulated beam passes through another set of ring electrodes, now electrically oating. The modulated beam induces a time alternating potential di erence between adjacent electrodes. Power can be drawn from the electrodes by connecting a resistive load. As energy is dissipated in the load, a corresponding drop in beam energy is measured. The simulation encapsulates the TWDEC process by reproducing the time-dependent transfer of energy and the particle deceleration due to the electric eld phase time variations.

Sensor data fusion for textured reconstruction and virtual representation of alpine scenes

NASA Astrophysics Data System (ADS)

Häufel, Gisela; Bulatov, Dimitri; Solbrig, Peter

2017-10-01

The concept of remote sensing is to provide information about a wide-range area without making physical contact with this area. If, additionally to satellite imagery, images and videos taken by drones provide a more up-to-date data at a higher resolution, or accurate vector data is downloadable from the Internet, one speaks of sensor data fusion. The concept of sensor data fusion is relevant for many applications, such as virtual tourism, automatic navigation, hazard assessment, etc. In this work, we describe sensor data fusion aiming to create a semantic 3D model of an extremely interesting yet challenging dataset: An alpine region in Southern Germany. A particular challenge of this work is that rock faces including overhangs are present in the input airborne laser point cloud. The proposed procedure for identification and reconstruction of overhangs from point clouds comprises four steps: Point cloud preparation, filtering out vegetation, mesh generation and texturing. Further object types are extracted in several interesting subsections of the dataset: Building models with textures from UAV (Unmanned Aerial Vehicle) videos, hills reconstructed as generic surfaces and textured by the orthophoto, individual trees detected by the watershed algorithm, as well as the vector data for roads retrieved from openly available shapefiles and GPS-device tracks. We pursue geo-specific reconstruction by assigning texture and width to roads of several pre-determined types and modeling isolated trees and rocks using commercial software. For visualization and simulation of the area, we have chosen the simulation system Virtual Battlespace 3 (VBS3). It becomes clear that the proposed concept of sensor data fusion allows a coarse reconstruction of a large scene and, at the same time, an accurate and up-to-date representation of its relevant subsections, in which simulation can take place.

Optimisation of confinement in a fusion reactor using a nonlinear turbulence model

NASA Astrophysics Data System (ADS)

Highcock, E. G.; Mandell, N. R.; Barnes, M.

2018-04-01

The confinement of heat in the core of a magnetic fusion reactor is optimised using a multidimensional optimisation algorithm. For the first time in such a study, the loss of heat due to turbulence is modelled at every stage using first-principles nonlinear simulations which accurately capture the turbulent cascade and large-scale zonal flows. The simulations utilise a novel approach, with gyrofluid treatment of the small-scale drift waves and gyrokinetic treatment of the large-scale zonal flows. A simple near-circular equilibrium with standard parameters is chosen as the initial condition. The figure of merit, fusion power per unit volume, is calculated, and then two control parameters, the elongation and triangularity of the outer flux surface, are varied, with the algorithm seeking to optimise the chosen figure of merit. A twofold increase in the plasma power per unit volume is achieved by moving to higher elongation and strongly negative triangularity.

Use of .sup.3 He.sup.30 + ICRF minority heating to simulate alpha particle heating

DOEpatents

Post, Jr., Douglass E.; Hwang, David Q.; Hovey, Jane

1986-04-22

Neutron activation due to high levels of neutron production in a first heated deuterium-tritium plasma is substantially reduced by using Ion Cyclotron Resonance Frequency (ICRF) heating of energetic .sup.3 He.sup.++ ions in a second deuterium-.sup.3 He.sup.++ plasma which exhibit an energy distribution and density similar to that of alpha particles in fusion reactor experiments to simulate fusion alpha particle heating in the first plasma. The majority of the fast .sup.3 He.sup.++ ions and their slowing down spectrum can be studied using either a modulated hydrogen beam source for producing excited states of He.sup.+ in combination with spectrometers or double charge exchange with a high energy neutral lithium beam and charged particle detectors at the plasma edge. The maintenance problems thus associated with neutron activation are substantially reduced permitting energetic alpha particle behavior to be studied in near term large fusion experiments.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Carbajal, L.; Warwick Univ., Coventry; Dendy, R. O.

Ion cyclotron emission (ICE) offers unique promise as a diagnostic of the fusion born alpha-particle population in magnetically confined plasmas. Pioneering observations from JET and TFTR found that ICE intensity P ICE scales approximately linearly with the measured neutron flux from fusion reactions, and with the inferred concentration, n /n i , of fusion-born alpha-particles confined within the plasma. We present fully nonlinear self-consistent kinetic simulations that reproduce this scaling for the first time. This resolves a longstanding question in the physics of fusion alpha particle confinement and stability in MCF plasmas. It confirms the MCI as the likely emissionmore » mechanism and greatly strengthens the basis for diagnostic exploitation of ICE in future burning plasmas.« less

Plasma confinement theory and transport simulation. Technical progress report, May 1, 1991--April 30, 1992

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ross, D.W.

The objectives are: (1) to advance the transport studies of tokamaks, including development and maintenance of the Magnetic Fusion Energy Database, and (2) to provide theoretical interpretation, modeling and equilibrium and stability studies for TEXT-Upgrade. Recent reports, publications, and conference presentations of the Fusion Research Center are listed.

Neutron counter based on beryllium activation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bienkowska, B.; Prokopowicz, R.; Kaczmarczyk, J.

2014-08-21

The fusion reaction occurring in DD plasma is followed by emission of 2.45 MeV neutrons, which carry out information about fusion reaction rate and plasma parameters and properties as well. Neutron activation of beryllium has been chosen for detection of DD fusion neutrons. The cross-section for reaction {sup 9}Be(n, α){sup 6}He has a useful threshold near 1 MeV, which means that undesirable multiple-scattered neutrons do not undergo that reaction and therefore are not recorded. The product of the reaction, {sup 6}He, decays with half-life T{sub 1/2} = 0.807 s emitting β{sup −} particles which are easy to detect. Large areamore » gas sealed proportional detector has been chosen as a counter of β–particles leaving activated beryllium plate. The plate with optimized dimensions adjoins the proportional counter entrance window. Such set-up is also equipped with appropriate electronic components and forms beryllium neutron activation counter. The neutron flux density on beryllium plate can be determined from the number of counts. The proper calibration procedure needs to be performed, therefore, to establish such relation. The measurements with the use of known β–source have been done. In order to determine the detector response function such experiment have been modeled by means of MCNP5–the Monte Carlo transport code. It allowed proper application of the results of transport calculations of β{sup −} particles emitted from radioactive {sup 6}He and reaching proportional detector active volume. In order to test the counter system and measuring procedure a number of experiments have been performed on PF devices. The experimental conditions have been simulated by means of MCNP5. The correctness of simulation outcome have been proved by measurements with known radioactive neutron source. The results of the DD fusion neutron measurements have been compared with other neutron diagnostics.« less

Estimating rice yield from MODIS-Landsat fusion data in Taiwan

NASA Astrophysics Data System (ADS)

Chen, C. R.; Chen, C. F.; Nguyen, S. T.

2017-12-01

Rice production monitoring with remote sensing is an important activity in Taiwan due to official initiatives. Yield estimation is a challenge in Taiwan because rice fields are small and fragmental. High spatiotemporal satellite data providing phenological information of rice crops is thus required for this monitoring purpose. This research aims to develop data fusion approaches to integrate daily Moderate Resolution Imaging Spectroradiometer (MODIS) and Landsat data for rice yield estimation in Taiwan. In this study, the low-resolution MODIS LST and emissivity data are used as reference data sources to obtain the high-resolution LST from Landsat data using the mixed-pixel analysis technique, and the time-series EVI data were derived the fusion of MODIS and Landsat spectral band data using STARFM method. The LST and EVI simulated results showed the close agreement between the LST and EVI obtained by the proposed methods with the reference data. The rice-yield model was established using EVI and LST data based on information of rice crop phenology collected from 371 ground survey sites across the country in 2014. The results achieved from the fusion datasets compared with the reference data indicated the close relationship between the two datasets with the correlation coefficient (R2) of 0.75 and root mean square error (RMSE) of 338.7 kgs, which were more accurate than those using the coarse-resolution MODIS LST data (R2 = 0.71 and RMSE = 623.82 kgs). For the comparison of total production, 64 towns located in the west part of Taiwan were used. The results also confirmed that the model using fusion datasets produced more accurate results (R2 = 0.95 and RMSE = 1,243 tons) than that using the course-resolution MODIS data (R2 = 0.91 and RMSE = 1,749 tons). This study demonstrates the application of MODIS-Landsat fusion data for rice yield estimation at the township level in Taiwan. The results obtained from the methods used in this study could be useful to policymakers; and thus, the methods can be transferable to other regions in the world for rice yield estimation.

Vehicle dynamic prediction systems with on-line identification of vehicle parameters and road conditions.

PubMed

Hsu, Ling-Yuan; Chen, Tsung-Lin

2012-11-13

This paper presents a vehicle dynamics prediction system, which consists of a sensor fusion system and a vehicle parameter identification system. This sensor fusion system can obtain the six degree-of-freedom vehicle dynamics and two road angles without using a vehicle model. The vehicle parameter identification system uses the vehicle dynamics from the sensor fusion system to identify ten vehicle parameters in real time, including vehicle mass, moment of inertial, and road friction coefficients. With above two systems, the future vehicle dynamics is predicted by using a vehicle dynamics model, obtained from the parameter identification system, to propagate with time the current vehicle state values, obtained from the sensor fusion system. Comparing with most existing literatures in this field, the proposed approach improves the prediction accuracy both by incorporating more vehicle dynamics to the prediction system and by on-line identification to minimize the vehicle modeling errors. Simulation results show that the proposed method successfully predicts the vehicle dynamics in a left-hand turn event and a rollover event. The prediction inaccuracy is 0.51% in a left-hand turn event and 27.3% in a rollover event.

Experimental investigation on charcoal adsorption for cryogenic pump application

NASA Astrophysics Data System (ADS)

Scannapiego, Matthieu; Day, Christian

2017-12-01

Fusion reactors are generating energy by nuclear fusion between deuterium and tritium. In order to evacuate the high gas throughputs from the plasma exhaust, large pumping speed systems are required. Within the European Fusion Programme, the Karlsruhe Institute of Technology (KIT) has taken the lead to design a three-stage cryogenic pump that can provide a separation function of hydrogen isotopes from the remaining gases; hence limiting the tritium inventory in the machine. A primary input parameter for the detailed design of a cryopump is the sticking coefficient between the gas and the pumping surface. For this purpose, the so-called TIMO open panel pump experiment was conducted in the TIMO-2 test facility at KIT in order to measure pumping speeds on an activated carbon surface cooled at temperatures between 6 K and 22 K, for various pure gases and gas mixtures, under fusion relevant gas flow conditions, and for two different geometrical pump configurations. The influences of the panel temperature, the gas throughput and the intake gas temperature on the pumping speed have been characterized, providing valuable qualitative results for the design of the three-stage cryopump. In a future work, supporting Monte Carlo simulations should allow for derivation of the sticking coefficients.

Vehicle Dynamic Prediction Systems with On-Line Identification of Vehicle Parameters and Road Conditions

PubMed Central

Hsu, Ling-Yuan; Chen, Tsung-Lin

2012-01-01

This paper presents a vehicle dynamics prediction system, which consists of a sensor fusion system and a vehicle parameter identification system. This sensor fusion system can obtain the six degree-of-freedom vehicle dynamics and two road angles without using a vehicle model. The vehicle parameter identification system uses the vehicle dynamics from the sensor fusion system to identify ten vehicle parameters in real time, including vehicle mass, moment of inertial, and road friction coefficients. With above two systems, the future vehicle dynamics is predicted by using a vehicle dynamics model, obtained from the parameter identification system, to propagate with time the current vehicle state values, obtained from the sensor fusion system. Comparing with most existing literatures in this field, the proposed approach improves the prediction accuracy both by incorporating more vehicle dynamics to the prediction system and by on-line identification to minimize the vehicle modeling errors. Simulation results show that the proposed method successfully predicts the vehicle dynamics in a left-hand turn event and a rollover event. The prediction inaccuracy is 0.51% in a left-hand turn event and 27.3% in a rollover event. PMID:23202231

Effects of alpha stopping power modelling on the ignition threshold in a directly-driven inertial confinement fusion capsule

DOE PAGES

Temporal, Mauro; Canaud, Benoit; Cayzac, Witold; ...

2017-05-25

The alpha-particle energy deposition mechanism modifies the ignition conditions of the thermonuclear Deuterium-Tritium fusion reactions, and constitutes a key issue in achieving high gain in Inertial Confinement Fusion implosions. One-dimensional hydrodynamic calculations have been performed with the code Multi-IFE to simulate the implosion of a capsule directly irradiated by a laser beam. The diffusion approximation for the alpha energy deposition has been used to optimize three laser profiles corresponding to different implosion velocities. A Monte-Carlo package has been included in Multi-IFE to calculate the alpha energy transport, and in this case the energy deposition uses both the LP and themore » BPS stopping power models. Homothetic transformations that maintain a constant implosion velocity have been used to map out the transition region between marginally-igniting and high-gain configurations. Furthermore, the results provided by the two models have been compared and it is found that – close to the ignition threshold – in order to produce the same fusion energy, the calculations performed with the BPS model require about 10% more invested energy with respect to the LP model.« less

NASA Astrophysics Data System (ADS)

Bechetti, Daniel H.; DuPont, John N.; deBarbadillo, John J.; Baker, Brian A.

2014-06-01

Thermodynamic and kinetic modeling were used to determine appropriate heat treatment schedules for homogenization and second phase dissolution in INCONEL® alloy 740H® (INCONEL and 740H are registered trademarks of Special Metals Corporation) fusion welds. Following these simulations, a two-step heat treatment process was applied to specimens from a single pass gas tungsten arc weld (GTAW). Scanning electron microscopy (SEM) has been used to assess the changes in the distribution of alloying elements as well as changes in the fraction of second phase particles within the fusion zone. Experimental results demonstrate that adequate homogenization of alloy 740H weld metal can be achieved by a 1373 K/4 h (1100 °C/4 h) treatment. Complete dissolution of second phase particles could not be completely achieved, even at exposure to temperatures near the alloy's solidus temperature. These results are in good agreement with thermodynamic and kinetic predictions.

Sensor fusion V; Proceedings of the Meeting, Boston, MA, Nov. 15-17, 1992

NASA Technical Reports Server (NTRS)

Schenker, Paul S. (Editor)

1992-01-01

Topics addressed include 3D object perception, human-machine interface in multisensor systems, sensor fusion architecture, fusion of multiple and distributed sensors, interface and decision models for sensor fusion, computational networks, simple sensing for complex action, multisensor-based control, and metrology and calibration of multisensor systems. Particular attention is given to controlling 3D objects by sketching 2D views, the graphical simulation and animation environment for flexible structure robots, designing robotic systems from sensorimotor modules, cylindrical object reconstruction from a sequence of images, an accurate estimation of surface properties by integrating information using Bayesian networks, an adaptive fusion model for a distributed detection system, multiple concurrent object descriptions in support of autonomous navigation, robot control with multiple sensors and heuristic knowledge, and optical array detectors for image sensors calibration. (No individual items are abstracted in this volume)

Sensor fusion IV: Control paradigms and data structures; Proceedings of the Meeting, Boston, MA, Nov. 12-15, 1991

NASA Technical Reports Server (NTRS)

Schenker, Paul S. (Editor)

1992-01-01

Various papers on control paradigms and data structures in sensor fusion are presented. The general topics addressed include: decision models and computational methods, sensor modeling and data representation, active sensing strategies, geometric planning and visualization, task-driven sensing, motion analysis, models motivated biology and psychology, decentralized detection and distributed decision, data fusion architectures, robust estimation of shapes and features, application and implementation. Some of the individual subjects considered are: the Firefly experiment on neural networks for distributed sensor data fusion, manifold traversing as a model for learning control of autonomous robots, choice of coordinate systems for multiple sensor fusion, continuous motion using task-directed stereo vision, interactive and cooperative sensing and control for advanced teleoperation, knowledge-based imaging for terrain analysis, physical and digital simulations for IVA robotics.

Optimization of tritium breeding and shielding analysis to plasma in ITER fusion reactor

DOE Office of Scientific and Technical Information (OSTI.GOV)

Indah Rosidah, M., E-mail: indah.maymunah@gmail.com; Suud, Zaki, E-mail: szaki@fi.itb.ac.id; Yazid, Putranto Ilham

The development of fusion energy is one of the important International energy strategies with the important milestone is ITER (International Thermonuclear Experimental Reactor) project, initiated by many countries, such as: America, Europe, and Japan who agreed to set up TOKAMAK type fusion reactor in France. In ideal fusion reactor the fuel is purely deuterium, but it need higher temperature of reactor. In ITER project the fuels are deuterium and tritium which need lower temperature of the reactor. In this study tritium for fusion reactor can be produced by using reaction of lithium with neutron in the blanket region. With themore » tritium breeding blanket which react between Li-6 in the blanket with neutron resulted from the plasma region. In this research the material used in each layer surrounding the plasma in the reactor is optimized. Moreover, achieving self-sufficiency condition in the reactor in order tritium has enough availability to be consumed for a long time. In order to optimize Tritium Breeding Ratio (TBR) value in the fusion reactor, there are several strategies considered here. The first requirement is making variation in Li-6 enrichment to be 60%, 70%, and 90%. But, the result of that condition can not reach TBR value better than with no enrichment. Because there is reduction of Li-7 percent when increasing Li-6 percent. The other way is converting neutron multiplier material with Pb. From this, we get TBR value better with the Be as neutron multiplier. Beside of TBR value, fusion reactor can analyze the distribution of neutron flux and dose rate of neutron to know the change of neutron concentration for each layer in reactor. From the simulation in this study, 97% neutron concentration can be absorbed by material in reactor, so it is good enough. In addition, it is required to analyze spectrum neutron energy in many layers in the fusion reactor such as in blanket, coolant, and divertor. Actually material in that layer can resist in high temperature and high pressure condition for more than ten years.« less

Molecular basis of endosomal-membrane association for the dengue virus envelope protein

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rogers, David M.; Kent, Michael S.; Rempe, Susan B.

Dengue virus is coated by an icosahedral shell of 90 envelope protein dimers that convert to trimers at low pH and promote fusion of its membrane with the membrane of the host endosome. We provide the first estimates for the free energy barrier and minimum for two key steps in this process: host membrane bending and protein–membrane binding. Both are studied using complementary membrane elastic, continuum electrostatics and all-atom molecular dynamics simulations. The predicted host membrane bending required to form an initial fusion stalk presents a 22–30 kcal/mol free energy barrier according to a constrained membrane elastic model. Combined continuummore » and molecular dynamics results predict a 15 kcal/mol free energy decrease on binding of each trimer of dengue envelope protein to a membrane with 30% anionic phosphatidylglycerol lipid. The bending cost depends on the preferred curvature of the lipids composing the host membrane leaflets, while the free energy gained for protein binding depends on the surface charge density of the host membrane. The fusion loop of the envelope protein inserts exactly at the level of the interface between the membrane's hydrophobic and head-group regions. As a result, the methods used in this work provide a means for further characterization of the structures and free energies of protein-assisted membrane fusion.« less

Molecular basis of endosomal-membrane association for the dengue virus envelope protein

DOE PAGES

Rogers, David M.; Kent, Michael S.; Rempe, Susan B.

2015-01-02

Dengue virus is coated by an icosahedral shell of 90 envelope protein dimers that convert to trimers at low pH and promote fusion of its membrane with the membrane of the host endosome. We provide the first estimates for the free energy barrier and minimum for two key steps in this process: host membrane bending and protein–membrane binding. Both are studied using complementary membrane elastic, continuum electrostatics and all-atom molecular dynamics simulations. The predicted host membrane bending required to form an initial fusion stalk presents a 22–30 kcal/mol free energy barrier according to a constrained membrane elastic model. Combined continuummore » and molecular dynamics results predict a 15 kcal/mol free energy decrease on binding of each trimer of dengue envelope protein to a membrane with 30% anionic phosphatidylglycerol lipid. The bending cost depends on the preferred curvature of the lipids composing the host membrane leaflets, while the free energy gained for protein binding depends on the surface charge density of the host membrane. The fusion loop of the envelope protein inserts exactly at the level of the interface between the membrane's hydrophobic and head-group regions. As a result, the methods used in this work provide a means for further characterization of the structures and free energies of protein-assisted membrane fusion.« less

LOW ACTIVATION JOINING OF SIC/SIC COMPOSITES FOR FUSION APPLICATIONS: MODELING DUAL-PHASE MICROSTRUCTURES AND DISSIMILAR MATERIAL JOINTS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Henager, Charles H.; Nguyen, Ba Nghiep; Kurtz, Richard J.

2016-03-31

Finite element continuum damage models (FE-CDM) have been developed to simulate and model dual-phase joints and cracked joints for improved analysis of SiC materials in nuclear environments. This report extends the analysis from the last reporting cycle by including results from dual-phase models and from cracked joint models.

A review on ab initio studies of static, transport, and optical properties of polystyrene under extreme conditions for inertial confinement fusion applications

NASA Astrophysics Data System (ADS)

Hu, S. X.; Collins, L. A.; Boehly, T. R.; Ding, Y. H.; Radha, P. B.; Goncharov, V. N.; Karasiev, V. V.; Collins, G. W.; Regan, S. P.; Campbell, E. M.

2018-05-01

Polystyrene (CH), commonly known as "plastic," has been one of the widely used ablator materials for capsule designs in inertial confinement fusion (ICF). Knowing its precise properties under high-energy-density conditions is crucial to understanding and designing ICF implosions through radiation-hydrodynamic simulations. For this purpose, systematic ab initio studies on the static, transport, and optical properties of CH, in a wide range of density and temperature conditions (ρ = 0.1 to 100 g/cm3 and T = 103 to 4 × 106 K), have been conducted using quantum molecular dynamics (QMD) simulations based on the density functional theory. We have built several wide-ranging, self-consistent material-properties tables for CH, such as the first-principles equation of state, the QMD-based thermal conductivity (κQMD) and ionization, and the first-principles opacity table. This paper is devoted to providing a review on (1) what results were obtained from these systematic ab initio studies; (2) how these self-consistent results were compared with both traditional plasma-physics models and available experiments; and (3) how these first-principles-based properties of polystyrene affect the predictions of ICF target performance, through both 1-D and 2-D radiation-hydrodynamic simulations. In the warm dense regime, our ab initio results, which can significantly differ from predictions of traditional plasma-physics models, compared favorably with experiments. When incorporated into hydrocodes for ICF simulations, these first-principles material properties of CH have produced significant differences over traditional models in predicting 1-D/2-D target performance of ICF implosions on OMEGA and direct-drive-ignition designs for the National Ignition Facility. Finally, we will discuss the implications of these studies on the current small-margin ICF target designs using a CH ablator.

Development of the dense plasma focus for short-pulse applications

NASA Astrophysics Data System (ADS)

Bennett, N.; Blasco, M.; Breeding, K.; Constantino, D.; DeYoung, A.; DiPuccio, V.; Friedman, J.; Gall, B.; Gardner, S.; Gatling, J.; Hagen, E. C.; Luttman, A.; Meehan, B. T.; Misch, M.; Molnar, S.; Morgan, G.; O'Brien, R.; Robbins, L.; Rundberg, R.; Sipe, N.; Welch, D. R.; Yuan, V.

2017-01-01

The dense plasma focus (DPF) has long been considered a compact source for pulsed neutrons and has traditionally been optimized for the total neutron yield. In this paper, we describe the efforts to optimize the DPF for short-pulse applications by introducing a reentrant cathode at the end of the coaxial plasma gun. The resulting neutron pulse widths are reduced by an average of 21 ±9 % from the traditional long-drift DPF design. Pulse widths and yields achieved from deuterium-tritium fusion at 2 MA are 61.8 ±30.7 ns FWHM and 1.84 ±0.49 ×1012 neutrons per shot. Simulations were conducted concurrently to elucidate the DPF operation and confirm the role of the reentrant cathode. A hybrid fluid-kinetic particle-in-cell modeling capability demonstrates correct sheath velocities, plasma instabilities, and fusion yield rates. Consistent with previous findings that the DPF is dominated by beam-target fusion from superthermal ions, we estimate that the thermonuclear contribution is at the 1% level.

Dust-Particle Transport in Tokamak Edge Plasmas

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pigarov, A Y; Krasheninnikov, S I; Soboleva, T K

2005-09-12

Dust particulates in the size range of 10nm-100{micro}m are found in all fusion devices. Such dust can be generated during tokamak operation due to strong plasma/material-surface interactions. Some recent experiments and theoretical estimates indicate that dust particles can provide an important source of impurities in the tokamak plasma. Moreover, dust can be a serious threat to the safety of next-step fusion devices. In this paper, recent experimental observations on dust in fusion devices are reviewed. A physical model for dust transport simulation, and a newly developed code DUSTT, are discussed. The DUSTT code incorporates both dust dynamics due to comprehensivemore » dust-plasma interactions as well as the effects of dust heating, charging, and evaporation. The code tracks test dust particles in realistic plasma backgrounds as provided by edge-plasma transport codes. Results are presented for dust transport in current and next-step tokamaks. The effect of dust on divertor plasma profiles and core plasma contamination is examined.« less

Speaker-independent phoneme recognition with a binaural auditory image model

NASA Astrophysics Data System (ADS)

Francis, Keith Ivan

1997-09-01

This dissertation presents phoneme recognition techniques based on a binaural fusion of outputs of the auditory image model and subsequent azimuth-selective phoneme recognition in a noisy environment. Background information concerning speech variations, phoneme recognition, current binaural fusion techniques and auditory modeling issues is explained. The research is constrained to sources in the frontal azimuthal plane of a simulated listener. A new method based on coincidence detection of neural activity patterns from the auditory image model of Patterson is used for azimuth-selective phoneme recognition. The method is tested in various levels of noise and the results are reported in contrast to binaural fusion methods based on various forms of correlation to demonstrate the potential of coincidence- based binaural phoneme recognition. This method overcomes smearing of fine speech detail typical of correlation based methods. Nevertheless, coincidence is able to measure similarity of left and right inputs and fuse them into useful feature vectors for phoneme recognition in noise.

Manufactured solutions for the three-dimensional Euler equations with relevance to Inertial Confinement Fusion

DOE Office of Scientific and Technical Information (OSTI.GOV)

Waltz, J., E-mail: jwaltz@lanl.gov; Canfield, T.R.; Morgan, N.R.

2014-06-15

We present a set of manufactured solutions for the three-dimensional (3D) Euler equations. The purpose of these solutions is to allow for code verification against true 3D flows with physical relevance, as opposed to 3D simulations of lower-dimensional problems or manufactured solutions that lack physical relevance. Of particular interest are solutions with relevance to Inertial Confinement Fusion (ICF) capsules. While ICF capsules are designed for spherical symmetry, they are hypothesized to become highly 3D at late time due to phenomena such as Rayleigh–Taylor instability, drive asymmetry, and vortex decay. ICF capsules also involve highly nonlinear coupling between the fluid dynamicsmore » and other physics, such as radiation transport and thermonuclear fusion. The manufactured solutions we present are specifically designed to test the terms and couplings in the Euler equations that are relevant to these phenomena. Example numerical results generated with a 3D Finite Element hydrodynamics code are presented, including mesh convergence studies.« less

Fusion and elastic scattering of 6Li + 58Ni at low energies

NASA Astrophysics Data System (ADS)

Aguilera, Elí F.; Amador-Valenzuela, Paulina; Martinez-Quiroz, Enrique; Lizcano, David; Garcia-Flores, Araceli; Kolata, James J.

2017-11-01

Sub-barrier fusion cross sections (σfus) for the 6Li + 58Ni system, obtained from the respective evaporation protons, are examined in the present work. With respect to expectations of a simple one-dimensional barrier penetration model, a large enhancement of the data is observed. Good consistency with equivalent data reported previously for similar systems is found. A comparison with total reaction cross sections (σR), deduced from elastic scattering measurements reported previously, indicates that σfus is close to σR within the measured energy range. To estimate the contribution of complete fusion (CF), an optical model analysis of the elastic scattering data is performed where CF is identified with the absorption in a short range volume potential. A surface polarization potential is added to the bare nuclear potential to simulate the effect of peripheral reactions. The results obtained indicate that other mechanisms different from CF may be dominant, especially in the lower energy region.

Content-Based Multi-Channel Network Coding Algorithm in the Millimeter-Wave Sensor Network

PubMed Central

Lin, Kai; Wang, Di; Hu, Long

2016-01-01

With the development of wireless technology, the widespread use of 5G is already an irreversible trend, and millimeter-wave sensor networks are becoming more and more common. However, due to the high degree of complexity and bandwidth bottlenecks, the millimeter-wave sensor network still faces numerous problems. In this paper, we propose a novel content-based multi-channel network coding algorithm, which uses the functions of data fusion, multi-channel and network coding to improve the data transmission; the algorithm is referred to as content-based multi-channel network coding (CMNC). The CMNC algorithm provides a fusion-driven model based on the Dempster-Shafer (D-S) evidence theory to classify the sensor nodes into different classes according to the data content. By using the result of the classification, the CMNC algorithm also provides the channel assignment strategy and uses network coding to further improve the quality of data transmission in the millimeter-wave sensor network. Extensive simulations are carried out and compared to other methods. Our simulation results show that the proposed CMNC algorithm can effectively improve the quality of data transmission and has better performance than the compared methods. PMID:27376302

Irradiation-induced microstructural evolution and mechanical properties in iron with and without helium

NASA Astrophysics Data System (ADS)

Okuniewski, Maria Ann

Ferritic-martensitic steels have been identified as candidate structural materials for Generation IV reactors, fusion systems, and accelerator driven systems (ADS). These steels have been selected because of their superior radiation resistance to void swelling, irradiation creep, and helium (He) and hydrogen (H) embrittlement at higher temperatures (T/Tm > 0.4). In fusion and ADS reactors the structural materials will be subjected to irradiation damage, as well as the introduction of He and H. The He and H can be introduced via (n,alpha) and (n,p) threshold reactions, respectively. Also protons can be directly implanted from the beam in an ADS. In fusion and ADS environments the He generation is approximately 10 appm/dpa and 150 appm/dpa. The H generation is approximately three to ten times higher than He production in ADS environments. The impact of these large generation rates of He and H impurities on microstructural evolution during irradiation is not well understood. The irradiation-induced microstructural evolution and its relationship to mechanical properties in body-centered cubic (bcc) iron (Fe) with and without He was systematically investigated. The bcc Fe was selected as a simplified material to serve as a basis for a reactor structural material that was exposed to varying He-to-damage ratios to simulate fusion (10 appm/dpa) and ADS (150 appm/dpa) environments. Through utilizing relatively pure, single crystal, bcc Fe, microstructural and mechanical properties effects from alloying elements can be reduced, if not eliminated. Ion irradiations were carried out at two temperature regimes (300 and 450°C). A coordinated group of experiments and simulations were carried out. Following specimen irradiations, the resultant microstructure and mechanical properties were evaluated with both non-destructive and destructive experimental techniques. The experimental techniques included positron annihilation spectroscopy (PAS), specifically, Doppler broadening spectroscopy (DBS) and positron annihilation lifetime spectroscopy (PALS); in-situ and ex-situ transmission electron microscopy (TEM), nanoindentation, and atomic force microscopy (AFM). Kinetic lattice Monte Carlo (KLMC) was selected as the modeling technique since it has the capability of producing mesoscale results that can be directly compared to the length and time scales of the experimental work. ATomic SUPerposition (ATSUP) was utilized to calculate positron lifetimes and W parameters in Fe as a function of vacancy concentration. The results of the experiments and simulations were directly compared and related. The major findings included: (1) A link was established between the irradiated microstructure and its impact on mechanical properties. This was achieved through the quantitative evaluation of the ex-situ TEM defect analyses and the relationship of nanohardness to yield strength. The microstructural results from KMC modeling were also related to the mechanical properties through the Dispersed Barrier Model. (2) KMC was identified as a complementary technique for microstructural evaluation since it resulted in a distribution of defects that were not visible via TEM, however they are known to be present based on the PAS results. (3) PAS results and KMC simulations were compared with ATSUP calculations to quantify defect size versus positron lifetime.

Distributed multimodal data fusion for large scale wireless sensor networks

NASA Astrophysics Data System (ADS)

Ertin, Emre

2006-05-01

Sensor network technology has enabled new surveillance systems where sensor nodes equipped with processing and communication capabilities can collaboratively detect, classify and track targets of interest over a large surveillance area. In this paper we study distributed fusion of multimodal sensor data for extracting target information from a large scale sensor network. Optimal tracking, classification, and reporting of threat events require joint consideration of multiple sensor modalities. Multiple sensor modalities improve tracking by reducing the uncertainty in the track estimates as well as resolving track-sensor data association problems. Our approach to solving the fusion problem with large number of multimodal sensors is construction of likelihood maps. The likelihood maps provide a summary data for the solution of the detection, tracking and classification problem. The likelihood map presents the sensory information in an easy format for the decision makers to interpret and is suitable with fusion of spatial prior information such as maps, imaging data from stand-off imaging sensors. We follow a statistical approach to combine sensor data at different levels of uncertainty and resolution. The likelihood map transforms each sensor data stream to a spatio-temporal likelihood map ideally suitable for fusion with imaging sensor outputs and prior geographic information about the scene. We also discuss distributed computation of the likelihood map using a gossip based algorithm and present simulation results.

Hybrid Rigid-Deformable Model for Prediction of Neighboring Intervertebral Disk Loads During Flexion Movement After Lumbar Interbody Fusion at L3-4 Level.

PubMed

Tuan Dao, Tien

2017-03-01

Knowledge of spinal loads in neighboring disks after interbody fusion plays an important role in the clinical decision of this treatment as well as in the elucidation of its effect. However, controversial findings are still noted in the literature. Moreover, there are no existing models for efficient prediction of intervertebral disk stresses within annulus fibrosus (AF) and nucleus pulposus (NP) regions. In this present study, a new hybrid rigid-deformable modeling workflow was established to quantify the mechanical stress behaviors within AF and NP regions of the L1-2, L2-3, and L4-5 disks after interbody fusion at L3-4 level. The changes in spinal loads were compared with results of the intact model without interbody fusion. The fusion outcomes revealed maximal stress changes (10%) in AF region of L1-2 disk and in NP region of L2-3 disk. The minimal stress change (1%) is noted at the NP region of the L1-2 disk. The validation of simulation outcomes of fused and intact lumbar spine models against those of other computational models and in vivo measurements showed good agreements. Thus, this present study may be used as a novel design guideline for a specific implant and surgical scenario of the lumbar spine disorders.

Engineering workstation: Sensor modeling

NASA Technical Reports Server (NTRS)

Pavel, M; Sweet, B.

1993-01-01

The purpose of the engineering workstation is to provide an environment for rapid prototyping and evaluation of fusion and image processing algorithms. Ideally, the algorithms are designed to optimize the extraction of information that is useful to a pilot for all phases of flight operations. Successful design of effective fusion algorithms depends on the ability to characterize both the information available from the sensors and the information useful to a pilot. The workstation is comprised of subsystems for simulation of sensor-generated images, image processing, image enhancement, and fusion algorithms. As such, the workstation can be used to implement and evaluate both short-term solutions and long-term solutions. The short-term solutions are being developed to enhance a pilot's situational awareness by providing information in addition to his direct vision. The long term solutions are aimed at the development of complete synthetic vision systems. One of the important functions of the engineering workstation is to simulate the images that would be generated by the sensors. The simulation system is designed to use the graphics modeling and rendering capabilities of various workstations manufactured by Silicon Graphics Inc. The workstation simulates various aspects of the sensor-generated images arising from phenomenology of the sensors. In addition, the workstation can be used to simulate a variety of impairments due to mechanical limitations of the sensor placement and due to the motion of the airplane. Although the simulation is currently not performed in real-time, sequences of individual frames can be processed, stored, and recorded in a video format. In that way, it is possible to examine the appearance of different dynamic sensor-generated and fused images.

Fusion interfaces for tactical environments: An application of virtual reality technology

NASA Technical Reports Server (NTRS)

Haas, Michael W.

1994-01-01

The term Fusion Interface is defined as a class of interface which integrally incorporates both virtual and nonvirtual concepts and devices across the visual, auditory, and haptic sensory modalities. A fusion interface is a multisensory virtually-augmented synthetic environment. A new facility has been developed within the Human Engineering Division of the Armstrong Laboratory dedicated to exploratory development of fusion interface concepts. This new facility, the Fusion Interfaces for Tactical Environments (FITE) Facility is a specialized flight simulator enabling efficient concept development through rapid prototyping and direct experience of new fusion concepts. The FITE Facility also supports evaluation of fusion concepts by operation fighter pilots in an air combat environment. The facility is utilized by a multidisciplinary design team composed of human factors engineers, electronics engineers, computer scientists, experimental psychologists, and oeprational pilots. The FITE computational architecture is composed of twenty-five 80486-based microcomputers operating in real-time. The microcomputers generate out-the-window visuals, in-cockpit and head-mounted visuals, localized auditory presentations, haptic displays on the stick and rudder pedals, as well as executing weapons models, aerodynamic models, and threat models.

Fusion of Hard and Soft Information in Nonparametric Density Estimation

DTIC Science & Technology

2015-06-10

and stochastic optimization models, in analysis of simulation output, and when instantiating probability models. We adopt a constrained maximum...particular, density estimation is needed for generation of input densities to simulation and stochastic optimization models, in analysis of simulation output...an essential step in simulation analysis and stochastic optimization is the generation of probability densities for input random variables; see for

Flexible Fusion Structure-Based Performance Optimization Learning for Multisensor Target Tracking

PubMed Central

Ge, Quanbo; Wei, Zhongliang; Cheng, Tianfa; Chen, Shaodong; Wang, Xiangfeng

2017-01-01

Compared with the fixed fusion structure, the flexible fusion structure with mixed fusion methods has better adjustment performance for the complex air task network systems, and it can effectively help the system to achieve the goal under the given constraints. Because of the time-varying situation of the task network system induced by moving nodes and non-cooperative target, and limitations such as communication bandwidth and measurement distance, it is necessary to dynamically adjust the system fusion structure including sensors and fusion methods in a given adjustment period. Aiming at this, this paper studies the design of a flexible fusion algorithm by using an optimization learning technology. The purpose is to dynamically determine the sensors’ numbers and the associated sensors to take part in the centralized and distributed fusion processes, respectively, herein termed sensor subsets selection. Firstly, two system performance indexes are introduced. Especially, the survivability index is presented and defined. Secondly, based on the two indexes and considering other conditions such as communication bandwidth and measurement distance, optimization models for both single target tracking and multi-target tracking are established. Correspondingly, solution steps are given for the two optimization models in detail. Simulation examples are demonstrated to validate the proposed algorithms. PMID:28481243

Improved two-point model for limiter scrape-off layer

NASA Astrophysics Data System (ADS)

Tokar, M. Z.; Kobayashi, M.; Feng, Y.

2004-10-01

An analytical model for a limiter scrape-off layer (SOL) is proposed, which takes self-consistently into account both conductive and convective contributions to the heat transport in SOL. The particle flows in the SOL main part are determined by considering the recycling of neutrals. The model allows us to interpret the results of numerical simulation by the code EMC3-EIRENE [Y. Feng, F. Sardei, P. Grigull, K. McCormick, J. Kisslinger, D. Reiter, and Y. Igitkhanov, Plasma Phys. Controlled Fusion 44, 611 (2002)] for the edge region of Tokamak Experiment for Technology Oriented Research (TEXTOR) [Proceedings of the 16th IEEE Symposium on Fusion Engineering, 1995 (Institute for Electrical and Electronics Engineers, Piscataway, NJ, 1995), p. 470].

First Observation of Cross-Beam Energy Transfer Mitigation for Direct-Drive Inertial Confinement Fusion Implosions Using Wavelength Detuning at the National Ignition Facility.

PubMed

Marozas, J A; Hohenberger, M; Rosenberg, M J; Turnbull, D; Collins, T J B; Radha, P B; McKenty, P W; Zuegel, J D; Marshall, F J; Regan, S P; Sangster, T C; Seka, W; Campbell, E M; Goncharov, V N; Bowers, M W; Di Nicola, J-M G; Erbert, G; MacGowan, B J; Pelz, L J; Yang, S T

2018-02-23

Cross-beam energy transfer (CBET) results from two-beam energy exchange via seeded stimulated Brillouin scattering, which detrimentally reduces ablation pressure and implosion velocity in direct-drive inertial confinement fusion. Mitigating CBET is demonstrated for the first time in inertial-confinement implosions at the National Ignition Facility by detuning the laser-source wavelengths (±2.3  Å UV) of the interacting beams. We show that, in polar direct-drive, wavelength detuning increases the equatorial region velocity experimentally by 16% and alters the in-flight shell morphology. These experimental observations are consistent with design predictions of radiation-hydrodynamic simulations that indicate a 10% increase in the average ablation pressure.

Fusion of KLMS and blob based pre-screener for buried landmine detection using ground penetrating radar

NASA Astrophysics Data System (ADS)

Baydar, Bora; Akar, Gözde Bozdaǧi.; Yüksel, Seniha E.; Öztürk, Serhat

2016-05-01

In this paper, a decision level fusion using multiple pre-screener algorithms is proposed for the detection of buried landmines from Ground Penetrating Radar (GPR) data. The Kernel Least Mean Square (KLMS) and the Blob Filter pre-screeners are fused together to work in real time with less false alarms and higher true detection rates. The effect of the kernel variance is investigated for the KLMS algorithm. Also, the results of the KLMS and KLMS+Blob filter algorithms are compared to the LMS method in terms of processing time and false alarm rates. Proposed algorithm is tested on both simulated data and real data collected at the field of IPA Defence at METU, Ankara, Turkey.

First Observation of Cross-Beam Energy Transfer Mitigation for Direct-Drive Inertial Confinement Fusion Implosions Using Wavelength Detuning at the National Ignition Facility

NASA Astrophysics Data System (ADS)

Marozas, J. A.; Hohenberger, M.; Rosenberg, M. J.; Turnbull, D.; Collins, T. J. B.; Radha, P. B.; McKenty, P. W.; Zuegel, J. D.; Marshall, F. J.; Regan, S. P.; Sangster, T. C.; Seka, W.; Campbell, E. M.; Goncharov, V. N.; Bowers, M. W.; Di Nicola, J.-M. G.; Erbert, G.; MacGowan, B. J.; Pelz, L. J.; Yang, S. T.

2018-02-01

Cross-beam energy transfer (CBET) results from two-beam energy exchange via seeded stimulated Brillouin scattering, which detrimentally reduces ablation pressure and implosion velocity in direct-drive inertial confinement fusion. Mitigating CBET is demonstrated for the first time in inertial-confinement implosions at the National Ignition Facility by detuning the laser-source wavelengths (±2.3 Å UV) of the interacting beams. We show that, in polar direct-drive, wavelength detuning increases the equatorial region velocity experimentally by 16% and alters the in-flight shell morphology. These experimental observations are consistent with design predictions of radiation-hydrodynamic simulations that indicate a 10% increase in the average ablation pressure.

Study of edge turbulence in dimensionally similar laboratory plasmas

NASA Astrophysics Data System (ADS)

Stroth, Ulrich

2003-10-01

In recent years, the numerical simulation of turbulence has made considerable progress. Predictions are made for large plasma volumes taking into account realistic magnetic geometries. Because of diagnostic limitations, in fusion plasmas the means of experimental testing of the models are rather limited. Toroidal low-temperature plasmas offer the possibility for detailed comparisons between experiment and simulation. Due to the reduced plasma parameters, the relevant quantities can be measured in the entire plasma. At the same time, the relevant non-dimensional parameters can be comparable to those in the edge of fusion plasmas. This presentation reports on results from the torsatron TJ-K [1,2] operated with a low-temperature plasma. The data are compared with simulations using the drift-Alfven-wave code DALF3 [3]. Langmuir probe arrays with 64 tips are used to measure the spatial structure of the turbulence. The same analyses techniques are applied to experimental and numerical data. The measured properties of spectra and probability density functions are reproduced by the code. Although the plasma in experiment and simulation does not exhibit critical pressure gradients, the radial transport fluctuations are strongly intermittent in both cases. Using Hydrogen, Helium and Argon as working gases, the scale parameter ρs could be varied by more than a factor of ten. As predicted by theory, the size of the turbulent eddies increases with ρ_s. The measured cross-phase between density and potential fluctuations are small, indicating the importance of the drift-wave dynamics for the turbulence in toroidal plasmas. The wave number spectra decay with an exponent of -3 as one would expect for the enstrophy cascade in 2D turbulence. [1] N. Krause et al., Rev. Sci. Instr. 73, 3474 (2002) [2] C. Lechte et al., New J. of Physics 4, 34 (2002) [3] B. Scott, Plasma Phys. Contr. Fusion 39, 1635 (1997)

Scaling magnetized liner inertial fusion on Z and future pulsed-power accelerators

DOE PAGES

Slutz, Stephen A.; Stygar, William A.; Gomez, Matthew R.; ...

2016-02-04

In this study, the MagLIF (Magnetized Liner Inertial Fusion) concept [S. A. Slutz et al., Phys. Plasmas 17, 056303 (2010)] has demonstrated fusion–relevant plasma conditions [M. R. Gomez et al., Phys. Rev. Lett. 113, 155003 (2014)] on the Z accelerator with a peak drive current of about 18 MA. We present 2D numerical simulations of the scaling of MagLIF on Z as a function of drive current, preheat energy, and applied magnetic field. The results indicate that deuterium-tritium (DT) fusion yields greater than 100 kJ could be possible on Z when all of these parameters are at the optimum values:more » i.e., peak current = 25 MA, deposited preheat energy = 5 kJ, and B z = 30 T. Much higher yields have been predicted [S. A. Slutz and R. A. Vesey, Phys. Rev. Lett. 108, 025003 (2012)] for MagLIF driven with larger peak currents. Two high performance pulsed-power accelerators (Z300 and Z800) based on linear-transformer-driver technology have been designed [W. A. Stygar et al., Phys. Rev. ST Accel. Beams 18, 110401 (2015)]. The Z300 design would provide 48 MA to a MagLIF load, while Z800 would provide 65 MA. Parameterized Thevenin-equivalent circuits were used to drive a series of 1D and 2D numerical MagLIF simulations with currents ranging from what Z can deliver now to what could be achieved by these conceptual future pulsed-power accelerators. 2D simulations of simple MagLIF targets containing just gaseous DT have yields of 18 MJ for Z300 and 440 MJ for Z800. The 2D simulated yield for Z800 is increased to 7 GJ by adding a layer of frozen DT ice to the inside of the liner.« less

Scaling magnetized liner inertial fusion on Z and future pulsed-power accelerators

DOE Office of Scientific and Technical Information (OSTI.GOV)

Slutz, Stephen A.; Stygar, William A.; Gomez, Matthew R.

In this study, the MagLIF (Magnetized Liner Inertial Fusion) concept [S. A. Slutz et al., Phys. Plasmas 17, 056303 (2010)] has demonstrated fusion–relevant plasma conditions [M. R. Gomez et al., Phys. Rev. Lett. 113, 155003 (2014)] on the Z accelerator with a peak drive current of about 18 MA. We present 2D numerical simulations of the scaling of MagLIF on Z as a function of drive current, preheat energy, and applied magnetic field. The results indicate that deuterium-tritium (DT) fusion yields greater than 100 kJ could be possible on Z when all of these parameters are at the optimum values:more » i.e., peak current = 25 MA, deposited preheat energy = 5 kJ, and B z = 30 T. Much higher yields have been predicted [S. A. Slutz and R. A. Vesey, Phys. Rev. Lett. 108, 025003 (2012)] for MagLIF driven with larger peak currents. Two high performance pulsed-power accelerators (Z300 and Z800) based on linear-transformer-driver technology have been designed [W. A. Stygar et al., Phys. Rev. ST Accel. Beams 18, 110401 (2015)]. The Z300 design would provide 48 MA to a MagLIF load, while Z800 would provide 65 MA. Parameterized Thevenin-equivalent circuits were used to drive a series of 1D and 2D numerical MagLIF simulations with currents ranging from what Z can deliver now to what could be achieved by these conceptual future pulsed-power accelerators. 2D simulations of simple MagLIF targets containing just gaseous DT have yields of 18 MJ for Z300 and 440 MJ for Z800. The 2D simulated yield for Z800 is increased to 7 GJ by adding a layer of frozen DT ice to the inside of the liner.« less

Scaling magnetized liner inertial fusion on Z and future pulsed-power accelerators

DOE Office of Scientific and Technical Information (OSTI.GOV)

Slutz, S. A.; Stygar, W. A.; Gomez, M. R.

The MagLIF (Magnetized Liner Inertial Fusion) concept [S. A. Slutz et al., Phys. Plasmas 17, 056303 (2010)] has demonstrated fusion–relevant plasma conditions [M. R. Gomez et al., Phys. Rev. Lett. 113, 155003 (2014)] on the Z accelerator with a peak drive current of about 18 MA. We present 2D numerical simulations of the scaling of MagLIF on Z as a function of drive current, preheat energy, and applied magnetic field. The results indicate that deuterium-tritium (DT) fusion yields greater than 100 kJ could be possible on Z when all of these parameters are at the optimum values: i.e., peak current = 25 MA, deposited preheatmore » energy = 5 kJ, and B{sub z} = 30 T. Much higher yields have been predicted [S. A. Slutz and R. A. Vesey, Phys. Rev. Lett. 108, 025003 (2012)] for MagLIF driven with larger peak currents. Two high performance pulsed-power accelerators (Z300 and Z800) based on linear-transformer-driver technology have been designed [W. A. Stygar et al., Phys. Rev. ST Accel. Beams 18, 110401 (2015)]. The Z300 design would provide 48 MA to a MagLIF load, while Z800 would provide 65 MA. Parameterized Thevenin-equivalent circuits were used to drive a series of 1D and 2D numerical MagLIF simulations with currents ranging from what Z can deliver now to what could be achieved by these conceptual future pulsed-power accelerators. 2D simulations of simple MagLIF targets containing just gaseous DT have yields of 18 MJ for Z300 and 440 MJ for Z800. The 2D simulated yield for Z800 is increased to 7 GJ by adding a layer of frozen DT ice to the inside of the liner.« less

Effective Thermal Property Estimation of Unitary Pebble Beds Based on a CFD-DEM Coupled Method for a Fusion Blanket

NASA Astrophysics Data System (ADS)

Chen, Lei; Chen, Youhua; Huang, Kai; Liu, Songlin

2015-12-01

Lithium ceramic pebble beds have been considered in the solid blanket design for fusion reactors. To characterize the fusion solid blanket thermal performance, studies of the effective thermal properties, i.e. the effective thermal conductivity and heat transfer coefficient, of the pebble beds are necessary. In this paper, a 3D computational fluid dynamics discrete element method (CFD-DEM) coupled numerical model was proposed to simulate heat transfer and thereby estimate the effective thermal properties. The DEM was applied to produce a geometric topology of a prototypical blanket pebble bed by directly simulating the contact state of each individual particle using basic interaction laws. Based on this geometric topology, a CFD model was built to analyze the temperature distribution and obtain the effective thermal properties. The current numerical model was shown to be in good agreement with the existing experimental data for effective thermal conductivity available in the literature. supported by National Special Project for Magnetic Confined Nuclear Fusion Energy of China (Nos. 2013GB108004, 2015GB108002, 2014GB122000 and 2014GB119000), and National Natural Science Foundation of China (No. 11175207)

3D-information fusion from very high resolution satellite sensors

NASA Astrophysics Data System (ADS)

Krauss, T.; d'Angelo, P.; Kuschk, G.; Tian, J.; Partovi, T.

2015-04-01

In this paper we show the pre-processing and potential for environmental applications of very high resolution (VHR) satellite stereo imagery like these from WorldView-2 or Pl'eiades with ground sampling distances (GSD) of half a metre to a metre. To process such data first a dense digital surface model (DSM) has to be generated. Afterwards from this a digital terrain model (DTM) representing the ground and a so called normalized digital elevation model (nDEM) representing off-ground objects are derived. Combining these elevation based data with a spectral classification allows detection and extraction of objects from the satellite scenes. Beside the object extraction also the DSM and DTM can directly be used for simulation and monitoring of environmental issues. Examples are the simulation of floodings, building-volume and people estimation, simulation of noise from roads, wave-propagation for cellphones, wind and light for estimating renewable energy sources, 3D change detection, earthquake preparedness and crisis relief, urban development and sprawl of informal settlements and much more. Also outside of urban areas volume information brings literally a new dimension to earth oberservation tasks like the volume estimations of forests and illegal logging, volume of (illegal) open pit mining activities, estimation of flooding or tsunami risks, dike planning, etc. In this paper we present the preprocessing from the original level-1 satellite data to digital surface models (DSMs), corresponding VHR ortho images and derived digital terrain models (DTMs). From these components we present how a monitoring and decision fusion based 3D change detection can be realized by using different acquisitions. The results are analyzed and assessed to derive quality parameters for the presented method. Finally the usability of 3D information fusion from VHR satellite imagery is discussed and evaluated.

Formulating Spatially Varying Performance in the Statistical Fusion Framework

PubMed Central

Landman, Bennett A.

2012-01-01

To date, label fusion methods have primarily relied either on global (e.g. STAPLE, globally weighted vote) or voxelwise (e.g. locally weighted vote) performance models. Optimality of the statistical fusion framework hinges upon the validity of the stochastic model of how a rater errs (i.e., the labeling process model). Hitherto, approaches have tended to focus on the extremes of potential models. Herein, we propose an extension to the STAPLE approach to seamlessly account for spatially varying performance by extending the performance level parameters to account for a smooth, voxelwise performance level field that is unique to each rater. This approach, Spatial STAPLE, provides significant improvements over state-of-the-art label fusion algorithms in both simulated and empirical data sets. PMID:22438513

Research on anisotropy of fusion-produced protons and neutrons emission from high-current plasma-focus discharges.

PubMed

Malinowski, K; Skladnik-Sadowska, E; Sadowski, M J; Szydlowski, A; Czaus, K; Kwiatkowski, R; Zaloga, D; Paduch, M; Zielinska, E

2015-01-01

The paper concerns fast protons and neutrons from D-D fusion reactions in a Plasma-Focus-1000U facility. Measurements were performed with nuclear-track detectors arranged in "sandwiches" of an Al-foil and two PM-355 detectors separated by a polyethylene-plate. The Al-foil eliminated all primary deuterons, but was penetrable for fast fusion protons. The foil and first PM-355 detector were penetrable for fast neutrons, which were converted into recoil-protons in the polyethylene and recorded in the second PM-355 detector. The "sandwiches" were irradiated by discharges of comparable neutron-yields. Analyses of etched tracks and computer simulations of the fusion-products behavior in the detectors were performed.

Simulation of Fusion Plasmas

ScienceCinema

Holland, Chris [UC San Diego, San Diego, California, United States

2017-12-09

The upcoming ITER experiment (www.iter.org) represents the next major milestone in realizing the promise of using nuclear fusion as a commercial energy source, by moving into the “burning plasma” regime where the dominant heat source is the internal fusion reactions. As part of its support for the ITER mission, the US fusion community is actively developing validated predictive models of the behavior of magnetically confined plasmas. In this talk, I will describe how the plasma community is using the latest high performance computing facilities to develop and refine our models of the nonlinear, multiscale plasma dynamics, and how recent advances in experimental diagnostics are allowing us to directly test and validate these models at an unprecedented level.

Research on anisotropy of fusion-produced protons and neutrons emission from high-current plasma-focus discharges

DOE Office of Scientific and Technical Information (OSTI.GOV)

Malinowski, K., E-mail: karol.malinowski@ncbj.gov.pl; Sadowski, M. J.; Szydlowski, A.

2015-01-15

The paper concerns fast protons and neutrons from D-D fusion reactions in a Plasma-Focus-1000U facility. Measurements were performed with nuclear-track detectors arranged in “sandwiches” of an Al-foil and two PM-355 detectors separated by a polyethylene-plate. The Al-foil eliminated all primary deuterons, but was penetrable for fast fusion protons. The foil and first PM-355 detector were penetrable for fast neutrons, which were converted into recoil-protons in the polyethylene and recorded in the second PM-355 detector. The “sandwiches” were irradiated by discharges of comparable neutron-yields. Analyses of etched tracks and computer simulations of the fusion-products behavior in the detectors were performed.

Negative Effect of Rapidly Resorbing Properties of Bioactive Glass-Ceramics as Bone Graft Substitute in a Rabbit Lumbar Fusion Model

PubMed Central

Lee, Jae Hyup; Ryu, Hyun-Seung; Seo, Jun-Hyuk; Lee, Do-Yoon; Chang, Bong-Soon

2014-01-01

Background Bioactive glass-ceramics have the ability to directly bind to bones and have been widely used as bone graft substitutes due to their high osteoconductivity and biocompatibility. CaO-SiO2-P2O5-B2O3 glass-ceramics are known to have good osteoconductivity and are used as bone graft extenders. Methods This study aimed to evaluate the effects of the resorbing properties of glass-ceramics in bone fusion after producing and analyzing three types of CaO-SiO2-P2O5-B2O3 glass-ceramics with high osteoconductivity that had enhanced resorption by having an increased B2O3 content. The three types of CaO-SiO2-P2O5-B2O3 glass-ceramics with B2O3 contents of 8.0, 9.0, and 9.5 weight % were designated and grouped as P20B80, P10B90, and P5B95, respectively. Glass-ceramic types were tested for fusion rates and bone formation by employing the lumbar 5-6 intertransverse process fusion model in 51 New Zealand male rabbits. Bioactivity was assessed by soaking in simulated body fluid (SBF). Results In vitro study results showed sufficient hydroxycarbonate apatite layer formation occurred for P20B80 in1 day, for P10B90 in 3 days, and for P5B95 in 5 days after soaking in SBF. For the rabbit lumbar spine posterolateral fusion model, the autograft group recorded a 100% fusion rate with levels significantly higher than those of P20B80 (29.4%), P10B90 (0%), and P5B95 (14.3%), with high resorbing properties. Resorbing property differences among the three glass-ceramic groups were not significant. Histological results showed new bone formation confirming osteoconductivity in all three types of glass-ceramics. Radiomorphometric results also confirmed the resorbing properties of the three glass-ceramic types. Conclusions The high resorbing properties and osteoconductivity of porous glass-ceramics can be advantageous as no glass-ceramics remain in the body. However, their relatively fast rate of resorption in the body negatively affects their role as an osteoconductive scaffold as glass-ceramics are resorbed before bony fusion. PMID:24605194

Identification of novel targets for HIV-1: Molecular dynamics simulation and binding energy calculations

NASA Astrophysics Data System (ADS)

Pandey, Vishnudatt; Tiwari, Gargi; Mall, Vijaya Shri; Tiwari, Rakesh Kumar; Ojha, R. P.

2018-05-01

HIV-1 envelope glycoprotein-mediated fusion is managed by the concerted coalescence of the HIV-1 gp41 N- and C- helical regions, which is a product in the formation of 6-helix bundles. These two regions are considered prime targets for peptides and antibodies that inhibit HIV-1 entry. There are so many rational method aimed to attach a rationally designed artificial tail to the C-terminus of HIV-1 fusion inhibitors to increase their antiviral potency. Here M. D. simulation was performed to go insight for study of C-terminal tail of Ile-Asp-Leu (IDL).

Fusion of Optimized Indicators from Advanced Driver Assistance Systems (ADAS) for Driver Drowsiness Detection

PubMed Central

Daza, Iván G.; Bergasa, Luis M.; Bronte, Sebastián; Yebes, J. Javier; Almazán, Javier; Arroyo, Roberto

2014-01-01

This paper presents a non-intrusive approach for monitoring driver drowsiness using the fusion of several optimized indicators based on driver physical and driving performance measures, obtained from ADAS (Advanced Driver Assistant Systems) in simulated conditions. The paper is focused on real-time drowsiness detection technology rather than on long-term sleep/awake regulation prediction technology. We have developed our own vision system in order to obtain robust and optimized driver indicators able to be used in simulators and future real environments. These indicators are principally based on driver physical and driving performance skills. The fusion of several indicators, proposed in the literature, is evaluated using a neural network and a stochastic optimization method to obtain the best combination. We propose a new method for ground-truth generation based on a supervised Karolinska Sleepiness Scale (KSS). An extensive evaluation of indicators, derived from trials over a third generation simulator with several test subjects during different driving sessions, was performed. The main conclusions about the performance of single indicators and the best combinations of them are included, as well as the future works derived from this study. PMID:24412904

Nuclear fusion of advanced fuels using converging focused ion beams

NASA Astrophysics Data System (ADS)

Egle, Brian James

The Six Ion Gun Fusion Experiment (SIGFE) was designed and built to investigate a possible avenue to increase the reaction rate efficiency of the D-D and D-3He nuclear fusion reactions in Inertial Electrostatic Confinement (IEC) devices to the levels required for several non-electric applications of nuclear fusion. The SIGFE is based on the seminal IEC experiment published by Hirsch in 1967, and is the first experiment to recreate the results and unique features of the Hirsch device. The SIGFE used six identical ion beams to focus and converge deuterium and helium-3 ions into a sphere of less than 2 mm at nearly mono-energetic ion energies up to 150 keV. With improved ion optics and diagnostics, the SIGFE concluded that within the investigated parameter space, the region where the ion beams converged accounted for less than 0.2% of the total D-D fusion reactions. The maximum D-D fusion rates were observed when the ion beams were intentionally defocused to strike the inside surface of the cathode lenses. In this defocused state, the total D-D fusion rate increased when the chamber pressure was decreased. The maximum D-D fusion rate was 4.3 x 107 neutrons per second at a cathode voltage of -130 kV, a total cathode current of 10 mA, and a chamber pressure of 27 mPa. The D and 3He ion beams were produced in six self-contained ion gun modules. The modules were each capable of at least 4 mA of ion current while maintaining a main chamber pressure as low as 13 mPa. The theoretically calculated extractable ion current agreed with the experiment within a factor of 2. A concept was also developed and evaluated for the production of radioisotopes from the 14.7 MeV D-3He fusion protons produced in an IEC device. Monte Carlo simulations of this concept determined that a D-3He fusion rate on the order of 1011 s-1 would be required for an IEC device to produce 1 mCi of the 11C radioisotope.

A tethering complex drives the terminal stage of SNARE-dependent membrane fusion

NASA Astrophysics Data System (ADS)

D'Agostino, Massimo; Risselada, Herre Jelger; Lürick, Anna; Ungermann, Christian; Mayer, Andreas

2017-11-01

Membrane fusion in eukaryotic cells mediates the biogenesis of organelles, vesicular traffic between them, and exo- and endocytosis of important signalling molecules, such as hormones and neurotransmitters. Distinct tasks in intracellular membrane fusion have been assigned to conserved protein systems. Tethering proteins mediate the initial recognition and attachment of membranes, whereas SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) protein complexes are considered as the core fusion engine. SNARE complexes provide mechanical energy to distort membranes and drive them through a hemifusion intermediate towards the formation of a fusion pore. This last step is highly energy-demanding. Here we combine the in vivo and in vitro fusion of yeast vacuoles with molecular simulations to show that tethering proteins are critical for overcoming the final energy barrier to fusion pore formation. SNAREs alone drive vacuoles only into the hemifused state. Tethering proteins greatly increase the volume of SNARE complexes and deform the site of hemifusion, which lowers the energy barrier for pore opening and provides the driving force. Thereby, tethering proteins assume a crucial mechanical role in the terminal stage of membrane fusion that is likely to be conserved at multiple steps of vesicular traffic. We therefore propose that SNAREs and tethering proteins should be considered as a single, non-dissociable device that drives fusion. The core fusion machinery may then be larger and more complex than previously thought.

An epidemic model for biological data fusion in ad hoc sensor networks

NASA Astrophysics Data System (ADS)

Chang, K. C.; Kotari, Vikas

2009-05-01

Bio terrorism can be a very refined and a catastrophic approach of attacking a nation. This requires the development of a complete architecture dedicatedly designed for this purpose which includes but is not limited to Sensing/Detection, Tracking and Fusion, Communication, and others. In this paper we focus on one such architecture and evaluate its performance. Various sensors for this specific purpose have been studied. The accent has been on use of Distributed systems such as ad-hoc networks and on application of epidemic data fusion algorithms to better manage the bio threat data. The emphasis has been on understanding the performance characteristics of these algorithms under diversified real time scenarios which are implemented through extensive JAVA based simulations. Through comparative studies on communication and fusion the performance of channel filter algorithm for the purpose of biological sensor data fusion are validated.

Study of the L-mode tokamak plasma “shortfall” with local and global nonlinear gyrokinetic δf particle-in-cell simulation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chowdhury, J.; Wan, Weigang; Chen, Yang

2014-11-15

The δ f particle-in-cell code GEM is used to study the transport “shortfall” problem of gyrokinetic simulations. In local simulations, the GEM results confirm the previously reported simulation results of DIII-D [Holland et al., Phys. Plasmas 16, 052301 (2009)] and Alcator C-Mod [Howard et al., Nucl. Fusion 53, 123011 (2013)] tokamaks with the continuum code GYRO. Namely, for DIII-D the simulations closely predict the ion heat flux at the core, while substantially underpredict transport towards the edge; while for Alcator C-Mod, the simulations show agreement with the experimental values of ion heat flux, at least within the range of experimental error.more » Global simulations are carried out for DIII-D L-mode plasmas to study the effect of edge turbulence on the outer core ion heat transport. The edge turbulence enhances the outer core ion heat transport through turbulence spreading. However, this edge turbulence spreading effect is not enough to explain the transport underprediction.« less

Fusion and quality analysis for remote sensing images using contourlet transform

NASA Astrophysics Data System (ADS)

Choi, Yoonsuk; Sharifahmadian, Ershad; Latifi, Shahram

2013-05-01

Recent developments in remote sensing technologies have provided various images with high spatial and spectral resolutions. However, multispectral images have low spatial resolution and panchromatic images have low spectral resolution. Therefore, image fusion techniques are necessary to improve the spatial resolution of spectral images by injecting spatial details of high-resolution panchromatic images. The objective of image fusion is to provide useful information by improving the spatial resolution and the spectral information of the original images. The fusion results can be utilized in various applications, such as military, medical imaging, and remote sensing. This paper addresses two issues in image fusion: i) image fusion method and ii) quality analysis of fusion results. First, a new contourlet-based image fusion method is presented, which is an improvement over the wavelet-based fusion. This fusion method is then applied to a case study to demonstrate its fusion performance. Fusion framework and scheme used in the study are discussed in detail. Second, quality analysis for the fusion results is discussed. We employed various quality metrics in order to analyze the fusion results both spatially and spectrally. Our results indicate that the proposed contourlet-based fusion method performs better than the conventional wavelet-based fusion methods.

Theory of formation of helical structures in a perfectly conducting, premagnetized Z-pinch liner

NASA Astrophysics Data System (ADS)

Yu, Edmund; Velikovich, Alexander; Peterson, Kyle

2014-10-01

The magnetized liner inertial fusion (MagLIF) concept uses an azimuthal magnetic field to collapse a thick metallic liner containing preheated fusion fuel. A critical component of the concept is an axial magnetic field, permeating both the fuel and surrounding liner, which reduces the compression necessary to achieve fusion conditions. Recent experiments demonstrate that a liner premagnetized with a 10 T axial field develops helical structures with a pitch significantly larger than an estimate of Bz /Bθ would suggest. The cause of the helical perturbations is still not understood. In this work, we present an analytic, linear theory in which we model the liner as a perfectly conducting metal, and study how bumps and divots on its surface redirect current flow, resulting in perturbations to B as well as j × B . We show that in the presence of axial and azimuthal magnetic field, the theory predicts divots will grow and deform at an angle determined by the magnetic field. We compare theoretical results with three dimensional, resistive MHD simulations. Sandia is a multiprogram laboratory operated by Sandia Corporation, a Lockheed Martin Company, for the National Nuclear Security Administration under DE-AC04-94AL85000.

Biomechanics of Hybrid Anterior Cervical Fusion and Artificial Disc Replacement in 3-Level Constructs: An In Vitro Investigation

PubMed Central

Liao, Zhenhua; Fogel, Guy R.; Pu, Ting; Gu, Hongsheng; Liu, Weiqiang

2015-01-01

Background The ideal surgical approach for cervical disk disease remains controversial, especially for multilevel cervical disease. The purpose of this study was to investigate the biomechanics of the cervical spine after 3-level hybrid surgery compared with 3-level anterior cervical discectomy and fusion (ACDF). Material/Methods Eighteen human cadaveric spines (C2-T1) were evaluated under displacement-input protocol. After intact testing, a simulated hybrid construct or fusion construct was created between C3 to C6 and tested in the following 3 conditions: 3-level disc plate disc (3DPD), 3-level plate disc plate (3PDP), and 3-level plate (3P). Results Compared to intact, almost 65~80% of motion was successfully restricted at C3-C6 fusion levels (p<0.05). 3DPD construct resulted in slight increase at the 3 instrumented levels (p>0.05). 3PDP construct resulted in significant decrease of ROM at C3-C6 levels less than 3P (p<0.05). Both 3DPD and 3PDP caused significant reduction of ROM at the arthrodesis level and produced motion increase at the arthroplasty level. For adjacent levels, 3P resulted in markedly increased contribution of both upper and lower adjacent levels (p<0.05). Significant motion increases lower than 3P were only noted at partly adjacent levels in some conditions for 3DPD and 3PDP (p<0.05). Conclusions ACDF eliminated motion within the construct and greatly increased adjacent motion. Artificial cervical disc replacement normalized motion of its segment and adjacent segments. While hybrid conditions failed to restore normal motion within the construct, they significantly normalized motion in adjacent segments compared with the 3-level ACDF condition. The artificial disc in 3-level constructs has biomechanical advantages compared to fusion in normalizing motion. PMID:26529430

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wieser, Patti; Hopkins, David

The DOE Princeton Plasma Physics Laboratory (PPPL) collaborates to develop fusion as a safe, clean and abundant energy source for the future. This video discusses PPPL's research and development on plasma, the fourth state of matter. In this simulation of plasma turbulence inside PPPL's National Spherical Torus Experiment, the colorful strings represent higher and lower electron density in turbulent plasma as it circles around a donut-shaped fusion reactor; red and orange are higher density. This image is among those featured in the slide show, "Plasmas are Hot and Fusion is Cool," a production of PPPL and the Princeton University Broadcastmore » Center.« less

Approximate models for the ion-kinetic regime in inertial-confinement-fusion capsule implosions

DOE PAGES

Hoffman, Nelson M.; Zimmerman, George B.; Molvig, Kim; ...

2015-05-19

“Reduced” (i.e., simplified or approximate) ion-kinetic (RIK) models in radiation-hydrodynamic simulations permit a useful description of inertial-confinement-fusion (ICF) implosions where kinetic deviations from hydrodynamic behavior are important. For implosions in or near the kinetic regime (i.e., when ion mean free paths are comparable to the capsule size), simulations using a RIK model give a detailed picture of the time- and space-dependent structure of imploding capsules, allow an assessment of the relative importance of various kinetic processes during the implosion, enable explanations of past and current observations, and permit predictions of the results of future experiments. The RIK simulation method describedmore » here uses moment-based reduced kinetic models for transport of mass, momentum, and energy by long-mean-free-path ions, a model for the decrease of fusion reactivity owing to the associated modification of the ion distribution function, and a model of hydrodynamic turbulent mixing. Transport models are based on local gradient-diffusion approximations for the transport of moments of the ion distribution functions, with coefficients to impose flux limiting or account for transport modification. After calibration against a reference set of ICF implosions spanning the hydrodynamic-to-kinetic transition, the method has useful, quantifiable predictive ability over a broad range of capsule parameter space. Calibrated RIK simulations show that an important contributor to ion species separation in ICF capsule implosions is the preferential flux of longer-mean-free-path species out of the fuel and into the shell, leaving the fuel relatively enriched in species with shorter mean free paths. Also, the transport of ion thermal energy is enhanced in the kinetic regime, causing the fuel region to have a more uniform, lower ion temperature, extending over a larger volume, than implied by clean simulations. Furthermore, we expect that the success of our simple approach will motivate continued theoretical research into the development of first-principles-based, comprehensive, self-consistent, yet useable models of kinetic multispecies ion behavior in ICF plasmas.« less

In-silico analysis on biofabricating vascular networks using kinetic Monte Carlo simulations.

PubMed

Sun, Yi; Yang, Xiaofeng; Wang, Qi

2014-03-01

We present a computational modeling approach to study the fusion of multicellular aggregate systems in a novel scaffold-less biofabrication process, known as 'bioprinting'. In this novel technology, live multicellular aggregates are used as fundamental building blocks to make tissues or organs (collectively known as the bio-constructs,) via the layer-by-layer deposition technique or other methods; the printed bio-constructs embedded in maturogens, consisting of nutrient-rich bio-compatible hydrogels, are then placed in bioreactors to undergo the cellular aggregate fusion process to form the desired functional bio-structures. Our approach reported here is an agent-based modeling method, which uses the kinetic Monte Carlo (KMC) algorithm to evolve the cellular system on a lattice. In this method, the cells and the hydrogel media, in which cells are embedded, are coarse-grained to material's points on a three-dimensional (3D) lattice, where the cell-cell and cell-medium interactions are quantified by adhesion and cohesion energies. In a multicellular aggregate system with a fixed number of cells and fixed amount of hydrogel media, where the effect of cell differentiation, proliferation and death are tactically neglected, the interaction energy is primarily dictated by the interfacial energy between cell and cell as well as between cell and medium particles on the lattice, respectively, based on the differential adhesion hypothesis. By using the transition state theory to track the time evolution of the multicellular system while minimizing the interfacial energy, KMC is shown to be an efficient time-dependent simulation tool to study the evolution of the multicellular aggregate system. In this study, numerical experiments are presented to simulate fusion and cell sorting during the biofabrication process of vascular networks, in which the bio-constructs are fabricated via engineering designs. The results predict the feasibility of fabricating the vascular structures via the bioprinting technology and demonstrate the morphological development process during cellular aggregate fusion in various engineering designed structures. The study also reveals that cell sorting will perhaps not significantly impact the final fabricated products, should the maturation process be well-controlled in bioprinting.

Fully non-linear multi-species Fokker-Planck-Landau collisions for gyrokinetic particle-in-cell simulations of fusion plasma

NASA Astrophysics Data System (ADS)

Hager, Robert; Yoon, E. S.; Ku, S.; D'Azevedo, E. F.; Worley, P. H.; Chang, C. S.

2015-11-01

We describe the implementation, and application of a time-dependent, fully nonlinear multi-species Fokker-Planck-Landau collision operator based on the single-species work of Yoon and Chang [Phys. Plasmas 21, 032503 (2014)] in the full-function gyrokinetic particle-in-cell codes XGC1 [Ku et al., Nucl. Fusion 49, 115021 (2009)] and XGCa. XGC simulations include the pedestal and scrape-off layer, where significant deviations of the particle distribution function from a Maxwellian can occur. Thus, in order to describe collisional effects on neoclassical and turbulence physics accurately, the use of a non-linear collision operator is a necessity. Our collision operator is based on a finite volume method using the velocity-space distribution functions sampled from the marker particles. Since the same fine configuration space mesh is used for collisions and the Poisson solver, the workload due to collisions can be comparable to or larger than the workload due to particle motion. We demonstrate that computing time spent on collisions can be kept affordable by applying advanced parallelization strategies while conserving mass, momentum, and energy to reasonable accuracy. We also show results of production scale XGCa simulations in the H-mode pedestal and compare to conventional theory. Work supported by US DOE OFES and OASCR.

Anomalous neutron yield in indirect-drive inertial-confinement-fusion due to the formation of collisionless shocks in the corona

NASA Astrophysics Data System (ADS)

Zhang, Wen-Shuai; Cai, Hong-Bo; Shan, Lian-Qiang; Zhang, Hua-Sen; Gu, Yu-Qiu; Zhu, Shao-Ping

2017-06-01

Observations of anomalous neutron yield in the indirect-drive inertial confinement fusion implosion experiments conducted at SG-III prototype and SG-II upgrade laser facilities are interpreted. The anomalous mechanism results in a neutron yield which is 100-times higher than that predicted by 1D radiation-hydrodynamic simulations. 2D radiation-hydrodynamic simulations show that the supersonic, radially directed gold (Au) plasma jets arising from the laser-hohlraum interactions can collide with the carbon-deuterium (CD) corona plasma of the compressed pellet. It is found that in the interaction front of the high-Z jet with the low-Z corona, with low density  ˜{{10}20}~\\text{c}{{\\text{m}}-3} and high temperature  ˜keV, kinetic effects become important. Particle-in-cell simulations indicate that an electrostatic shock wave can be driven when the high-temperature Au jet expands into the low-temperature CD corona. Deuterium ions with an amount of  ˜1015 can be accelerated to  ˜25 keV by the collisionless shock wave, thus causing efficient neutron productions though the beam-target method by stopping these energetic ions in the corona. The evaluated neutron yield is consistent with the experiments conducted at SG laser facilities.

Laser welding in space

NASA Technical Reports Server (NTRS)

Kaukler, W. F.; Workman, G. L.

1991-01-01

Autogenous welds in 304 stainless steel were performed by Nd-YAG laser heating in a simulated space environment. Simulation consists of welding on the NASA KC-135 aircraft to produce the microgravity and by containing the specimen in a vacuum chamber. Experimental results show that the microgravity welds are stronger, harder in the fusion zone, have deeper penetration and have a rougher surface rippling of the weld pool than one-g welds. To perform laser welding in space, a solar-pumped laser concept that significantly increases the laser conversion efficiency and makes welding viable despite the limited power availability of spacecraft is proposed.

Daily ambient air pollution metrics for five cities: Evaluation of data-fusion-based estimates and uncertainties

NASA Astrophysics Data System (ADS)

Friberg, Mariel D.; Kahn, Ralph A.; Holmes, Heather A.; Chang, Howard H.; Sarnat, Stefanie Ebelt; Tolbert, Paige E.; Russell, Armistead G.; Mulholland, James A.

2017-06-01

Spatiotemporal characterization of ambient air pollutant concentrations is increasingly relying on the combination of observations and air quality models to provide well-constrained, spatially and temporally complete pollutant concentration fields. Air quality models, in particular, are attractive, as they characterize the emissions, meteorological, and physiochemical process linkages explicitly while providing continuous spatial structure. However, such modeling is computationally intensive and has biases. The limitations of spatially sparse and temporally incomplete observations can be overcome by blending the data with estimates from a physically and chemically coherent model, driven by emissions and meteorological inputs. We recently developed a data fusion method that blends ambient ground observations and chemical-transport-modeled (CTM) data to estimate daily, spatially resolved pollutant concentrations and associated correlations. In this study, we assess the ability of the data fusion method to produce daily metrics (i.e., 1-hr max, 8-hr max, and 24-hr average) of ambient air pollution that capture spatiotemporal air pollution trends for 12 pollutants (CO, NO2, NOx, O3, SO2, PM10, PM2.5, and five PM2.5 components) across five metropolitan areas (Atlanta, Birmingham, Dallas, Pittsburgh, and St. Louis), from 2002 to 2008. Three sets of comparisons are performed: (1) the CTM concentrations are evaluated for each pollutant and metropolitan domain, (2) the data fusion concentrations are compared with the monitor data, (3) a comprehensive cross-validation analysis against observed data evaluates the quality of the data fusion model simulations across multiple metropolitan domains. The resulting daily spatial field estimates of air pollutant concentrations and uncertainties are not only consistent with observations, emissions, and meteorology, but substantially improve CTM-derived results for nearly all pollutants and all cities, with the exception of NO2 for Birmingham. The greatest improvements occur for O3 and PM2.5. Squared spatiotemporal correlation coefficients range between simulations and observations determined using cross-validation across all cities for air pollutants of secondary and mixed origins are R2 = 0.88-0.93 (O3), 0.81-0.89 (SO4), 0.67-0.83 (PM2.5), 0.52-0.72 (NO3), 0.43-0.80 (NH4), 0.32-0.51 (OC), and 0.14-0.71 (PM10). Results for relatively homogeneous pollutants of secondary origin, tend to be better than those for more spatially heterogeneous (larger spatial gradients) pollutants of primary origin (NOx, CO, SO2 and EC). Generally, background concentrations and spatial concentration gradients reflect interurban airshed complexity and the effects of regional transport, whereas daily spatial pattern variability shows intra-urban consistency in the fused data. With sufficiently high CTM spatial resolution, traffic-related pollutants exhibit gradual concentration gradients that peak toward the urban centers. Ambient pollutant concentration uncertainty estimates for the fused data are both more accurate and smaller than those for either the observations or the model simulations alone.

Exploring magnetized liner inertial fusion with a semi-analytic model

DOE PAGES

McBride, Ryan D.; Slutz, Stephen A.; Vesey, Roger A.; ...

2016-01-01

In this study, we explore magnetized liner inertial fusion (MagLIF) [S. A. Slutz et al., Phys. Plasmas 17, 056303 (2010)] using a semi-analytic model [R. D. McBride and S. A. Slutz, Phys. Plasmas 22, 052708 (2015)]. Specifically, we present simulation results from this model that: (a) illustrate the parameter space, energetics, and overall system efficiencies of MagLIF; (b) demonstrate the dependence of radiative loss rates on the radial fraction of the fuel that is preheated; (c) explore some of the recent experimental results of the MagLIF program at Sandia National Laboratories [M. R. Gomez et al., Phys. Rev. Lett. 113,more » 155003 (2014)]; (d) highlight the experimental challenges presently facing the MagLIF program; and (e) demonstrate how increases to the preheat energy, fuel density, axial magnetic field, and drive current could affect future MagLIF performance.« less

Fusion of spectral and panchromatic images using false color mapping and wavelet integrated approach

NASA Astrophysics Data System (ADS)

Zhao, Yongqiang; Pan, Quan; Zhang, Hongcai

2006-01-01

With the development of sensory technology, new image sensors have been introduced that provide a greater range of information to users. But as the power limitation of radiation, there will always be some trade-off between spatial and spectral resolution in the image captured by specific sensors. Images with high spatial resolution can locate objects with high accuracy, whereas images with high spectral resolution can be used to identify the materials. Many applications in remote sensing require fusing low-resolution imaging spectral images with panchromatic images to identify materials at high resolution in clutter. A pixel-based false color mapping and wavelet transform integrated fusion algorithm is presented in this paper, the resulting images have a higher information content than each of the original images and retain sensor-specific image information. The simulation results show that this algorithm can enhance the visibility of certain details and preserve the difference of different materials.

Thermographic Measurements of the Commercial Laser Powder Bed Fusion Process at NIST

PubMed Central

Lane, Brandon; Moylan, Shawn; Whitenton, Eric; Ma, Li

2016-01-01

Measurement of the high-temperature melt pool region in the laser powder bed fusion (L-PBF) process is a primary focus of researchers to further understand the dynamic physics of the heating, melting, adhesion, and cooling which define this commercially popular additive manufacturing process. This paper will detail the design, execution, and results of high speed, high magnification in-situ thermographic measurements conducted at the National Institute of Standards and Technology (NIST) focusing on the melt pool region of a commercial L-PBF process. Multiple phenomena are observed including plasma plume and hot particle ejection from the melt region. The thermographic measurement process will be detailed with emphasis on the ‘measurability’ of observed phenomena and the sources of measurement uncertainty. Further discussion will relate these thermographic results to other efforts at NIST towards L-PBF process finite element simulation and development of in-situ sensing and control methodologies. PMID:28058036

Thermographic Measurements of the Commercial Laser Powder Bed Fusion Process at NIST.

PubMed

Lane, Brandon; Moylan, Shawn; Whitenton, Eric; Ma, Li

2016-01-01

Measurement of the high-temperature melt pool region in the laser powder bed fusion (L-PBF) process is a primary focus of researchers to further understand the dynamic physics of the heating, melting, adhesion, and cooling which define this commercially popular additive manufacturing process. This paper will detail the design, execution, and results of high speed, high magnification in-situ thermographic measurements conducted at the National Institute of Standards and Technology (NIST) focusing on the melt pool region of a commercial L-PBF process. Multiple phenomena are observed including plasma plume and hot particle ejection from the melt region. The thermographic measurement process will be detailed with emphasis on the 'measurability' of observed phenomena and the sources of measurement uncertainty. Further discussion will relate these thermographic results to other efforts at NIST towards L-PBF process finite element simulation and development of in-situ sensing and control methodologies.

Exploring magnetized liner inertial fusion with a semi-analytic model

DOE Office of Scientific and Technical Information (OSTI.GOV)

McBride, R. D.; Slutz, S. A.; Vesey, R. A.

In this paper, we explore magnetized liner inertial fusion (MagLIF) [S. A. Slutz et al., Phys. Plasmas 17, 056303 (2010)] using a semi-analytic model [R. D. McBride and S. A. Slutz, Phys. Plasmas 22, 052708 (2015)]. Specifically, we present simulation results from this model that: (a) illustrate the parameter space, energetics, and overall system efficiencies of MagLIF; (b) demonstrate the dependence of radiative loss rates on the radial fraction of the fuel that is preheated; (c) explore some of the recent experimental results of the MagLIF program at Sandia National Laboratories [M. R. Gomez et al., Phys. Rev. Lett. 113,more » 155003 (2014)]; (d) highlight the experimental challenges presently facing the MagLIF program; and (e) demonstrate how increases to the preheat energy, fuel density, axial magnetic field, and drive current could affect future MagLIF performance.« less

Exploring magnetized liner inertial fusion with a semi-analytic model

DOE Office of Scientific and Technical Information (OSTI.GOV)

McBride, Ryan D.; Slutz, Stephen A.; Vesey, Roger A.

In this study, we explore magnetized liner inertial fusion (MagLIF) [S. A. Slutz et al., Phys. Plasmas 17, 056303 (2010)] using a semi-analytic model [R. D. McBride and S. A. Slutz, Phys. Plasmas 22, 052708 (2015)]. Specifically, we present simulation results from this model that: (a) illustrate the parameter space, energetics, and overall system efficiencies of MagLIF; (b) demonstrate the dependence of radiative loss rates on the radial fraction of the fuel that is preheated; (c) explore some of the recent experimental results of the MagLIF program at Sandia National Laboratories [M. R. Gomez et al., Phys. Rev. Lett. 113,more » 155003 (2014)]; (d) highlight the experimental challenges presently facing the MagLIF program; and (e) demonstrate how increases to the preheat energy, fuel density, axial magnetic field, and drive current could affect future MagLIF performance.« less

Evaluation of Sintering Behaviors of Saprolitic Nickeliferous Laterite Based on Quaternary Basicity

NASA Astrophysics Data System (ADS)

Luo, Jun; Li, Guanghui; Rao, Mingjun; Zhang, Yuanbo; Peng, Zhiwei; Zhi, Qian; Jiang, Tao

2015-09-01

The sintering behaviors of saprolitic nickeliferous laterite with various quaternary basicities [(CaO + MgO)/(SiO2 + Al2O3) mass ratio] in a reductive atmosphere are investigated by simulative sintering and validated by sintering pot tests. The simulative sintering results show that the generation of diopside (CaMgSi2O6) with low melting point is the key reason for the decrease in characteristic fusion temperatures when the quaternary basicity increases from 0.5 to 0.8-1.0. Continuous increase of basicity leads to transformation of diopside (CaMgSi2O6) into akermanite (Ca2MgSi2O7), which adversely increases the characteristic fusion temperatures. These findings are confirmed by the sinter pot tests, which demonstrate that the sintering indexes including vertical sintering velocity (VSV), yield ( Y), and productivity ( P), can be improved by optimizing quaternary basicity. At basicity of 1.0, the VSV, Y, P, and ISO tumbling index reach 49.2 mm/min, 80.5%, 1.0 t/(h m2), and 66.5%, respectively.

Microcharge neutralization transport experiments and simulations for ion-driven inertial confinement fusion

DOE Office of Scientific and Technical Information (OSTI.GOV)

Olson, C.L.; Hanson, D.L.; Poukey, J.W.

Space charge neutralization for intense beams for inertial confinement fusion is usually assumed to be perfect. However, small charge clumps in the beam will not be totally charge neutralized, and the residual net minimum potential set by electron trapping (e{phi} {approx} {1/2}m{sub e}v{sup 2}{sub i}, where m{sub e} is the electron mass and v{sub i} is the ion velocity) may lead to a substantial microdivergence. Experiments on the SABRE accelerator and simulations with the IPROP computer code are being performed to assess this mechanism. The authors have successfully created a 5 mrad beam on the SABRE accelerator, by expanding themore » beam (a process consistent with Liouville`s theorem) and, by passing the beam through a plate with pinholes, they have created low divergence beamlets to study this mechanism. Results clearly show: (1) at low pressures, trapping does neutralize the beamlets, but only down to e{phi} {approx} {1/2}m{sub e}v{sup 2}{sub i}; and (2) at higher pressures ({approx} 0.1-1 Torr), plasma shielding does remove the effect.« less

SPECSweb Multistatic Tracking on a Truth-Blind Simulated Scenario of the MSTWG

DTIC Science & Technology

2009-07-01

communications links and fusion/tracking processes, producing too many false tracks. The Specular-Cued Surveillance Web (SPECSweb) multistatic tracker...information from the multistatic nodes to a fusion center. A concept referred to as the “Specular-Cued Surveillance Web (SPECSweb)” is being...producing too many false tracks. The Specular-Cued Surveillance Web (SPECSweb) multistatic tracker mitigates these problems through implementation of two

A Coalition Approach to Higher-Level Fusion

DTIC Science & Technology

2009-07-01

environment and as a simulation which operates without any human interaction . In a typical wargame, WISE might portray a complex warfighting...the environment , while higher-level fusion is about establishing the story behind the data. Thus, achieving situational awareness for the users of...It is important to manage the relationship between the users and the virtual adviser so that context can be conveyed without disrupting the users

3D Neutronic Analysis in MHD Calculations at ARIES-ST Fusion Reactors Systems

NASA Astrophysics Data System (ADS)

Hançerliogulları, Aybaba; Cini, Mesut

2013-10-01

In this study, we developed new models for liquid wall (FW) state at ARIES-ST fusion reactor systems. ARIES-ST is a 1,000 MWe fusion reactor system based on a low aspect ratio ST plasma. In this article, we analyzed the characteristic properties of magnetohydrodynamics (MHD) and heat transfer conditions by using Monte-Carlo simulation methods (ARIES Team et al. in Fusion Eng Des 49-50:689-695, 2000; Tillack et al. in Fusion Eng Des 65:215-261, 2003) . In fusion applications, liquid metals are traditionally considered to be the best working fluids. The working liquid must be a lithium-containing medium in order to provide adequate tritium that the plasma is self-sustained and that the fusion is a renewable energy source. As for Flibe free surface flows, the MHD effects caused by interaction with the mean flow is negligible, while a fairly uniform flow of thick can be maintained throughout the reactor based on 3-D MHD calculations. In this study, neutronic parameters, that is to say, energy multiplication factor radiation, heat flux and fissile fuel breeding were researched for fusion reactor with various thorium and uranium molten salts. Sufficient tritium amount is needed for the reactor to work itself. In the tritium breeding ratio (TBR) >1.05 ARIES-ST fusion model TBR is >1.1 so that tritium self-sufficiency is maintained for DT fusion systems (Starke et al. in Fusion Energ Des 84:1794-1798, 2009; Najmabadi et al. in Fusion Energ Des 80:3-23, 2006).

Canonical Correlation Analysis for Feature-Based Fusion of Biomedical Imaging Modalities and Its Application to Detection of Associative Networks in Schizophrenia.

PubMed

Correa, Nicolle M; Li, Yi-Ou; Adalı, Tülay; Calhoun, Vince D

2008-12-01

Typically data acquired through imaging techniques such as functional magnetic resonance imaging (fMRI), structural MRI (sMRI), and electroencephalography (EEG) are analyzed separately. However, fusing information from such complementary modalities promises to provide additional insight into connectivity across brain networks and changes due to disease. We propose a data fusion scheme at the feature level using canonical correlation analysis (CCA) to determine inter-subject covariations across modalities. As we show both with simulation results and application to real data, multimodal CCA (mCCA) proves to be a flexible and powerful method for discovering associations among various data types. We demonstrate the versatility of the method with application to two datasets, an fMRI and EEG, and an fMRI and sMRI dataset, both collected from patients diagnosed with schizophrenia and healthy controls. CCA results for fMRI and EEG data collected for an auditory oddball task reveal associations of the temporal and motor areas with the N2 and P3 peaks. For the application to fMRI and sMRI data collected for an auditory sensorimotor task, CCA results show an interesting joint relationship between fMRI and gray matter, with patients with schizophrenia showing more functional activity in motor areas and less activity in temporal areas associated with less gray matter as compared to healthy controls. Additionally, we compare our scheme with an independent component analysis based fusion method, joint-ICA that has proven useful for such a study and note that the two methods provide complementary perspectives on data fusion.

Object Kinetic Monte Carlo Simulations of Radiation Damage In Bulk Tungsten

NASA Astrophysics Data System (ADS)

Nandipati, Giridhar; Setyawan, Wahyu; Heinisch, Howard; Roche, Kenneth; Kurtz, Richard; Wirth, Brian

2015-11-01

Results are presented for the evolution of radiation damage in bulk tungsten investigated using the object KMC simulation tool, KSOME, as a function of dose, dose rate and primary knock-on atom (PKA) energies in the range of 10 to 100 keV, at temperatures of 300, 1025 and 2050 K. At 300 K, the number density of vacancies changes minimally with dose rate while the number density of vacancy clusters slightly decreases with dose rate indicating that larger clusters are formed at higher dose rates. Although the average vacancy cluster size increases slightly, the vast majority exists as mono-vacancies. At 1025 K void lattice formation was observed at all dose rates for cascades below 60 keV and at lower dose rates for higher PKA energies. After the appearance of initial features of the void lattice, vacancy cluster density increased minimally while the average vacancy cluster size increases rapidly with dose. At 2050 K, no accumulation of defects was observed over a broad range of dose rates for all PKA energies studied in this work. Further comparisons of results of irradiation simulations at various dose rates and PKA spectra, representative of the High Flux Isotope Reactor and future fusion relevant irradiation facilities will be discussed. The U.S. Department of Energy, Office of Fusion Energy Sciences (FES) and Office of Advanced Scientific Computing Research (ASCR) has supported this study through the SciDAC-3 program.

On Fusing Recursive Traversals of K-d Trees

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rajbhandari, Samyam; Kim, Jinsung; Krishnamoorthy, Sriram

Loop fusion is a key program transformation for data locality optimization that is implemented in production compilers. But optimizing compilers currently cannot exploit fusion opportunities across a set of recursive tree traversal computations with producer-consumer relationships. In this paper, we develop a compile-time approach to dependence characterization and program transformation to enable fusion across recursively specified traversals over k-ary trees. We present the FuseT source-to-source code transformation framework to automatically generate fused composite recursive operators from an input program containing a sequence of primitive recursive operators. We use our framework to implement fused operators for MADNESS, Multiresolution Adaptive Numerical Environmentmore » for Scientific Simulation. We show that locality optimization through fusion can offer more than an order of magnitude performance improvement.« less

Estimating workload using EEG spectral power and ERPs in the n-back task

NASA Astrophysics Data System (ADS)

Brouwer, Anne-Marie; Hogervorst, Maarten A.; van Erp, Jan B. F.; Heffelaar, Tobias; Zimmerman, Patrick H.; Oostenveld, Robert

2012-08-01

Previous studies indicate that both electroencephalogram (EEG) spectral power (in particular the alpha and theta band) and event-related potentials (ERPs) (in particular the P300) can be used as a measure of mental work or memory load. We compare their ability to estimate workload level in a well-controlled task. In addition, we combine both types of measures in a single classification model to examine whether this results in higher classification accuracy than either one alone. Participants watched a sequence of visually presented letters and indicated whether or not the current letter was the same as the one (n instances) before. Workload was varied by varying n. We developed different classification models using ERP features, frequency power features or a combination (fusion). Training and testing of the models simulated an online workload estimation situation. All our ERP, power and fusion models provide classification accuracies between 80% and 90% when distinguishing between the highest and the lowest workload condition after 2 min. For 32 out of 35 participants, classification was significantly higher than chance level after 2.5 s (or one letter) as estimated by the fusion model. Differences between the models are rather small, though the fusion model performs better than the other models when only short data segments are available for estimating workload.

Lineage fusion in Galápagos giant tortoises.

PubMed

Garrick, Ryan C; Benavides, Edgar; Russello, Michael A; Hyseni, Chaz; Edwards, Danielle L; Gibbs, James P; Tapia, Washington; Ciofi, Claudio; Caccone, Adalgisa

2014-11-01

Although many classic radiations on islands are thought to be the result of repeated lineage splitting, the role of past fusion is rarely known because during these events, purebreds are rapidly replaced by a swarm of admixed individuals. Here, we capture lineage fusion in action in a Galápagos giant tortoise species, Chelonoidis becki, from Wolf Volcano (Isabela Island). The long generation time of Galápagos tortoises and dense sampling (841 individuals) of genetic and demographic data were integral in detecting and characterizing this phenomenon. In C. becki, we identified two genetically distinct, morphologically cryptic lineages. Historical reconstructions show that they colonized Wolf Volcano from Santiago Island in two temporally separated events, the first estimated to have occurred ~199 000 years ago. Following arrival of the second wave of colonists, both lineages coexisted for approximately ~53 000 years. Within that time, they began fusing back together, as microsatellite data reveal widespread introgressive hybridization. Interestingly, greater mate selectivity seems to be exhibited by purebred females of one of the lineages. Forward-in-time simulations predict rapid extinction of the early arriving lineage. This study provides a rare example of reticulate evolution in action and underscores the power of population genetics for understanding the past, present and future consequences of evolutionary phenomena associated with lineage fusion. © 2014 John Wiley & Sons Ltd.

Isotopic dependence of fusion enhancement of various heavy ion systems using energy dependent Woods-Saxon potential

NASA Astrophysics Data System (ADS)

Gautam, Manjeet Singh

2015-01-01

In the present work, the fusion of symmetric and asymmetric projectile-target combinations are deeply analyzed within the framework of energy dependent Woods-Saxon potential model (EDWSP model) in conjunction with one dimensional Wong formula and the coupled channel code CCFULL. The neutron transfer channels and the inelastic surface excitations of collision partners are dominating mode of couplings and the coupling of relative motion of colliding nuclei to such relevant internal degrees of freedom produces a significant fusion enhancement at sub-barrier energies. It is quite interesting that the effects of dominant intrinsic degrees of freedom such as multi-phonon vibrational states, neutron transfer channels and proton transfer channels can be simulated by introducing the energy dependence in the nucleus-nucleus potential (EDWSP model). In the EDWSP model calculations, a wide range of diffuseness parameter ranging from a = 0.85 fm to a = 0.97 fm, which is much larger than a value (a = 0.65 fm) extracted from the elastic scattering data, is needed to reproduce sub-barrier fusion data. However, such diffuseness anomaly, which might be an artifact of some dynamical effects, has been resolved by trajectory fluctuation dissipation (TFD) model wherein the resulting nucleus-nucleus potential possesses normal diffuseness parameter.

A laser device for fusion of nasal mucosa

NASA Astrophysics Data System (ADS)

Sooklal, Valmiki; McClure, Jesse; Hooper, Luke; Larson, Michael

2010-02-01

A prototype device has been created to fuse septal tissue membranes as an alternative to sutures or staples through the controlled application of laser heating and pressure to induce protein denaturation and subsequent tissue fusion, through renaturation and intertwining, across the interface. Lasers have been used to close wounds in controlled laboratory tests over the last 15 years. Many encouraging results have been obtained; however, no commercial delivery systems are currently available. This is due primarily to two factors: requiring an inordinate amount of experience on the part of the operator, and attempting to achieve general applicability for multiple tissue systems. The present device overcomes these barriers as it is tailored for the particular application of septal laser fusion, namely for the coaptation of mucoperichondrial membranes. The important parameters involved in fusing biological tissues are identified. The development of the device followed from computational modeling based on Monte Carlo simulation of photon transport and on engineering firstprinciples. Experiments were designed and analyzed using orthogonal arrays, employing a subset of the relevant parameters, i.e., laser irradiance, dwell time and spot size, for a range of wavelengths. The in vitro fusion experiments employed 1cm by 1cm sections of equine nasal mucosa having a nominal thickness of 1mm.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mitrani, J

Bayesian networks (BN) are an excellent tool for modeling uncertainties in systems with several interdependent variables. A BN is a directed acyclic graph, and consists of a structure, or the set of directional links between variables that depend on other variables, and conditional probabilities (CP) for each variable. In this project, we apply BN's to understand uncertainties in NIF ignition experiments. One can represent various physical properties of National Ignition Facility (NIF) capsule implosions as variables in a BN. A dataset containing simulations of NIF capsule implosions was provided. The dataset was generated from a radiation hydrodynamics code, and itmore » contained 120 simulations of 16 variables. Relevant knowledge about the physics of NIF capsule implosions and greedy search algorithms were used to search for hypothetical structures for a BN. Our preliminary results found 6 links between variables in the dataset. However, we thought there should have been more links between the dataset variables based on the physics of NIF capsule implosions. Important reasons for the paucity of links are the relatively small size of the dataset, and the sampling of the values for dataset variables. Another factor that might have caused the paucity of links is the fact that in the dataset, 20% of the simulations represented successful fusion, and 80% didn't, (simulations of unsuccessful fusion are useful for measuring certain diagnostics) which skewed the distributions of several variables, and possibly reduced the number of links. Nevertheless, by illustrating the interdependencies and conditional probabilities of several parameters and diagnostics, an accurate and complete BN built from an appropriate simulation set would provide uncertainty quantification for NIF capsule implosions.« less

A Method for Improving the Pose Accuracy of a Robot Manipulator Based on Multi-Sensor Combined Measurement and Data Fusion

PubMed Central

Liu, Bailing; Zhang, Fumin; Qu, Xinghua

2015-01-01

An improvement method for the pose accuracy of a robot manipulator by using a multiple-sensor combination measuring system (MCMS) is presented. It is composed of a visual sensor, an angle sensor and a series robot. The visual sensor is utilized to measure the position of the manipulator in real time, and the angle sensor is rigidly attached to the manipulator to obtain its orientation. Due to the higher accuracy of the multi-sensor, two efficient data fusion approaches, the Kalman filter (KF) and multi-sensor optimal information fusion algorithm (MOIFA), are used to fuse the position and orientation of the manipulator. The simulation and experimental results show that the pose accuracy of the robot manipulator is improved dramatically by 38%∼78% with the multi-sensor data fusion. Comparing with reported pose accuracy improvement methods, the primary advantage of this method is that it does not require the complex solution of the kinematics parameter equations, increase of the motion constraints and the complicated procedures of the traditional vision-based methods. It makes the robot processing more autonomous and accurate. To improve the reliability and accuracy of the pose measurements of MCMS, the visual sensor repeatability is experimentally studied. An optimal range of 1 × 0.8 × 1 ∼ 2 × 0.8 × 1 m in the field of view (FOV) is indicated by the experimental results. PMID:25850067

Effects of non-local electron transport in one-dimensional and two-dimensional simulations of shock-ignited inertial confinement fusion targets

NASA Astrophysics Data System (ADS)

Marocchino, A.; Atzeni, S.; Schiavi, A.

2014-01-01

In some regions of a laser driven inertial fusion target, the electron mean-free path can become comparable to or even longer than the electron temperature gradient scale-length. This can be particularly important in shock-ignited (SI) targets, where the laser-spike heated corona reaches temperatures of several keV. In this case, thermal conduction cannot be described by a simple local conductivity model and a Fick's law. Fluid codes usually employ flux-limited conduction models, which preserve causality, but lose important features of the thermal flow. A more accurate thermal flow modeling requires convolution-like non-local operators. In order to improve the simulation of SI targets, the non-local electron transport operator proposed by Schurtz-Nicolaï-Busquet [G. P. Schurtz et al., Phys. Plasmas 7, 4238 (2000)] has been implemented in the DUED fluid code. Both one-dimensional (1D) and two-dimensional (2D) simulations of SI targets have been performed. 1D simulations of the ablation phase highlight that while the shock profile and timing might be mocked up with a flux-limiter; the electron temperature profiles exhibit a relatively different behavior with no major effects on the final gain. The spike, instead, can only roughly be reproduced with a fixed flux-limiter value. 1D target gain is however unaffected, provided some minor tuning of laser pulses. 2D simulations show that the use of a non-local thermal conduction model does not affect the robustness to mispositioning of targets driven by quasi-uniform laser irradiation. 2D simulations performed with only two final polar intense spikes yield encouraging results and support further studies.

The effects of convergence ratio on the implosion behavior of DT layered inertial confinement fusion capsules

DOE PAGES

Haines, Brian M.; Yi, S. A.; Olson, R. E.; ...

2017-07-10

The wetted foam capsule design for inertial confinement fusion capsules, which includes a foam layer wetted with deuterium-tritium liquid, enables layered capsule implosions with a wide range of hot-spot convergence ratios (CR) on the National Ignition Facility. In this paper, we present a full-scale wetted foam capsule design that demonstrates high gain in one-dimensional simulations. In these simulations, increasing the convergence ratio leads to an improved capsule yield due to higher hot-spot temperatures and increased fuel areal density. High-resolution two-dimensional simulations of this design are presented with detailed and well resolved models for the capsule fill tube, support tent, surfacemore » roughness, and predicted asymmetries in the x-ray drive. Our modeling of these asymmetries is validated by comparisons with available experimental data. In 2D simulations of the full-scale wetted foam capsule design, jetting caused by the fill tube is prevented by the expansion of the tungsten-doped shell layer due to preheat. While the impacts of surface roughness and predicted asymmetries in the x-ray drive are enhanced by convergence effects, likely underpredicted in 2D at high CR, simulations predict that the capsule is robust to these features. Nevertheless, the design is highly susceptible to the effects of the capsule support tent, which negates all of the one-dimensional benefits of increasing the convergence ratio. Indeed, when the support tent is included in simulations, the yield decreases as the convergence ratio is increased for CR > 20. Finally and nevertheless, the results suggest that the full-scale wetted foam design has the potential to outperform ice layer capsules given currently achievable levels of asymmetries when fielded at low convergence ratios (CR < 20).« less

The effects of convergence ratio on the implosion behavior of DT layered inertial confinement fusion capsules

NASA Astrophysics Data System (ADS)

Haines, Brian M.; Yi, S. A.; Olson, R. E.; Khan, S. F.; Kyrala, G. A.; Zylstra, A. B.; Bradley, P. A.; Peterson, R. R.; Kline, J. L.; Leeper, R. J.; Shah, R. C.

2017-07-01

The wetted foam capsule design for inertial confinement fusion capsules, which includes a foam layer wetted with deuterium-tritium liquid, enables layered capsule implosions with a wide range of hot-spot convergence ratios (CR) on the National Ignition Facility. We present a full-scale wetted foam capsule design that demonstrates high gain in one-dimensional simulations. In these simulations, increasing the convergence ratio leads to an improved capsule yield due to higher hot-spot temperatures and increased fuel areal density. High-resolution two-dimensional simulations of this design are presented with detailed and well resolved models for the capsule fill tube, support tent, surface roughness, and predicted asymmetries in the x-ray drive. Our modeling of these asymmetries is validated by comparisons with available experimental data. In 2D simulations of the full-scale wetted foam capsule design, jetting caused by the fill tube is prevented by the expansion of the tungsten-doped shell layer due to preheat. While the impacts of surface roughness and predicted asymmetries in the x-ray drive are enhanced by convergence effects, likely underpredicted in 2D at high CR, simulations predict that the capsule is robust to these features. Nevertheless, the design is highly susceptible to the effects of the capsule support tent, which negates all of the one-dimensional benefits of increasing the convergence ratio. Indeed, when the support tent is included in simulations, the yield decreases as the convergence ratio is increased for CR > 20. Nevertheless, the results suggest that the full-scale wetted foam design has the potential to outperform ice layer capsules given currently achievable levels of asymmetries when fielded at low convergence ratios (CR < 20).

Constraining a complex biogeochemical model for CO2 and N2O emission simulations from various land uses by model-data fusion

NASA Astrophysics Data System (ADS)

Houska, Tobias; Kraus, David; Kiese, Ralf; Breuer, Lutz

2017-07-01

This study presents the results of a combined measurement and modelling strategy to analyse N2O and CO2 emissions from adjacent arable land, forest and grassland sites in Hesse, Germany. The measured emissions reveal seasonal patterns and management effects, including fertilizer application, tillage, harvest and grazing. The measured annual N2O fluxes are 4.5, 0.4 and 0.1 kg N ha-1 a-1, and the CO2 fluxes are 20.0, 12.2 and 3.0 t C ha-1 a-1 for the arable land, grassland and forest sites, respectively. An innovative model-data fusion concept based on a multicriteria evaluation (soil moisture at different depths, yield, CO2 and N2O emissions) is used to rigorously test the LandscapeDNDC biogeochemical model. The model is run in a Latin-hypercube-based uncertainty analysis framework to constrain model parameter uncertainty and derive behavioural model runs. The results indicate that the model is generally capable of predicting trace gas emissions, as evaluated with RMSE as the objective function. The model shows a reasonable performance in simulating the ecosystem C and N balances. The model-data fusion concept helps to detect remaining model errors, such as missing (e.g. freeze-thaw cycling) or incomplete model processes (e.g. respiration rates after harvest). This concept further elucidates the identification of missing model input sources (e.g. the uptake of N through shallow groundwater on grassland during the vegetation period) and uncertainty in the measured validation data (e.g. forest N2O emissions in winter months). Guidance is provided to improve the model structure and field measurements to further advance landscape-scale model predictions.

Multi-sources data fusion framework for remote triage prioritization in telehealth.

PubMed

Salman, O H; Rasid, M F A; Saripan, M I; Subramaniam, S K

2014-09-01

The healthcare industry is streamlining processes to offer more timely and effective services to all patients. Computerized software algorithm and smart devices can streamline the relation between users and doctors by providing more services inside the healthcare telemonitoring systems. This paper proposes a multi-sources framework to support advanced healthcare applications. The proposed framework named Multi Sources Healthcare Architecture (MSHA) considers multi-sources: sensors (ECG, SpO2 and Blood Pressure) and text-based inputs from wireless and pervasive devices of Wireless Body Area Network. The proposed framework is used to improve the healthcare scalability efficiency by enhancing the remote triaging and remote prioritization processes for the patients. The proposed framework is also used to provide intelligent services over telemonitoring healthcare services systems by using data fusion method and prioritization technique. As telemonitoring system consists of three tiers (Sensors/ sources, Base station and Server), the simulation of the MSHA algorithm in the base station is demonstrated in this paper. The achievement of a high level of accuracy in the prioritization and triaging patients remotely, is set to be our main goal. Meanwhile, the role of multi sources data fusion in the telemonitoring healthcare services systems has been demonstrated. In addition to that, we discuss how the proposed framework can be applied in a healthcare telemonitoring scenario. Simulation results, for different symptoms relate to different emergency levels of heart chronic diseases, demonstrate the superiority of our algorithm compared with conventional algorithms in terms of classify and prioritize the patients remotely.

Electron heat transport comparison in the Large Helical Device and TJ-II

DOE Office of Scientific and Technical Information (OSTI.GOV)

Garcia, J.; Dies, J.; Castejon, F.

2007-10-15

The electron heat transport in the Large Helical Device (LHD) [K. Ida, T. Shimozuma, H. Funaba et al., Phys. Rev. Lett. 91, 085003 (2003)] and TJ-II [F. Castejon, V. Tribaldos, I. Garcia-Cortes, E. de la Luna, J. Herranz, I. Pastor, T. Estrada, and TJ-II Team, Nucl. Fusion 42, 271 (2002)] is analyzed by means of the TOTAL [K. Yamazaki and T. Amano, Nucl. Fusion 32, 4 (1992)] and PRETOR-Stellarator [J. Dies, F. Castejon, J. M. Fontdecaba, J. Fontanet, J. Izquierdo, G. Cortes, and C. Alejaldre, Proceedings of the 29th European Physical Society Conference on Plasma Physics and Controlled Fusion, Montreux,more » 2002, Europhysics Conference Abstracts, 2004, Vol. 26B, P-5.027] plasma simulation codes and assuming a global transport model mixing GyroBohm-like drift wave model and other drift wave model with shorter wavelength. The stabilization of the GyroBohm-like model by the ExB shear has been also taken into account. Results show how such kind of electron heat transport can simulate experimental evidence in both devices, leading to the electron internal transport barrier (eITB) formation in the LHD and to the so-called 'enhanced heat confinement regimes' in TJ-II when electron density is low enough. Therefore, two sources for the anomalous electron heat transport can coexist in plasmas with eITB; however, for each device the relative importance of anomalous and neoclassical transport can be different.« less

Verification of Modelica-Based Models with Analytical Solutions for Tritium Diffusion

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rader, Jordan D.; Greenwood, Michael Scott; Humrickhouse, Paul W.

Here, tritium transport in metal and molten salt fluids combined with diffusion through high-temperature structural materials is an important phenomenon in both magnetic confinement fusion (MCF) and molten salt reactor (MSR) applications. For MCF, tritium is desirable to capture for fusion fuel. For MSRs, uncaptured tritium potentially can be released to the environment. In either application, quantifying the time- and space-dependent tritium concentration in the working fluid(s) and structural components is necessary.Whereas capability exists specifically for calculating tritium transport in such systems (e.g., using TMAP for fusion reactors), it is desirable to unify the calculation of tritium transport with othermore » system variables such as dynamic fluid and structure temperature combined with control systems such as those that might be found in a system code. Some capability for radioactive trace substance transport exists in thermal-hydraulic systems codes (e.g., RELAP5-3D); however, this capability is not coupled to species diffusion through solids. Combined calculations of tritium transport and thermal-hydraulic solution have been demonstrated with TRIDENT but only for a specific type of MSR.Researchers at Oak Ridge National Laboratory have developed a set of Modelica-based dynamic system modeling tools called TRANsient Simulation Framework Of Reconfigurable Models (TRANSFORM) that were used previously to model advanced fission reactors and associated systems. In this system, the augmented TRANSFORM library includes dynamically coupled fluid and solid trace substance transport and diffusion. Results from simulations are compared against analytical solutions for verification.« less

Verification of Modelica-Based Models with Analytical Solutions for Tritium Diffusion

DOE PAGES

Rader, Jordan D.; Greenwood, Michael Scott; Humrickhouse, Paul W.

2018-03-20

Here, tritium transport in metal and molten salt fluids combined with diffusion through high-temperature structural materials is an important phenomenon in both magnetic confinement fusion (MCF) and molten salt reactor (MSR) applications. For MCF, tritium is desirable to capture for fusion fuel. For MSRs, uncaptured tritium potentially can be released to the environment. In either application, quantifying the time- and space-dependent tritium concentration in the working fluid(s) and structural components is necessary.Whereas capability exists specifically for calculating tritium transport in such systems (e.g., using TMAP for fusion reactors), it is desirable to unify the calculation of tritium transport with othermore » system variables such as dynamic fluid and structure temperature combined with control systems such as those that might be found in a system code. Some capability for radioactive trace substance transport exists in thermal-hydraulic systems codes (e.g., RELAP5-3D); however, this capability is not coupled to species diffusion through solids. Combined calculations of tritium transport and thermal-hydraulic solution have been demonstrated with TRIDENT but only for a specific type of MSR.Researchers at Oak Ridge National Laboratory have developed a set of Modelica-based dynamic system modeling tools called TRANsient Simulation Framework Of Reconfigurable Models (TRANSFORM) that were used previously to model advanced fission reactors and associated systems. In this system, the augmented TRANSFORM library includes dynamically coupled fluid and solid trace substance transport and diffusion. Results from simulations are compared against analytical solutions for verification.« less

Mechanical Coupling via the Membrane Fusion SNARE Protein Syntaxin 1A: A Molecular Dynamics Study

PubMed Central

Knecht, Volker; Grubmüller, Helmut

2003-01-01

SNARE trans complexes between membranes likely promote membrane fusion. For the t-SNARE syntaxin 1A involved in synaptic transmission, the secondary structure and bending stiffness of the five-residue juxtamembrane linker is assumed to determine the required mechanical energy transfer from the cytosolic core complex to the membrane. These properties have here been studied by molecular dynamics and annealing simulations for the wild-type and a C-terminal-prolongated mutant within a neutral and an acidic bilayer, suggesting linker stiffnesses above 1.7 but below 50 × 10−3 kcal mol−1 deg−2. The transmembrane helix was found to be tilted by 15° and tightly anchored within the membrane with a stiffness of 4–5 kcal mol−1 Å−2. The linker turned out to be marginally helical and strongly influenced by its lipid environment. Charged lipids increased the helicity and H3 helix tilt stiffness. For the wild type, the linker was seen embedded deeply within the polar region of the bilayer, whereas the prolongation shifted the linker outward. This reduced its helicity and increased its average tilt, thereby presumably reducing fusion efficiency. Our results suggest that partially unstructured linkers provide considerable mechanical coupling; the energy transduced cooperatively by the linkers in a native fusion event is thus estimated to be 3–8 kcal/mol, implying a two-to-five orders of magnitude fusion rate increase. PMID:12609859

Kinetic turbulence simulations at extreme scale on leadership-class systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Bei; Ethier, Stephane; Tang, William

2013-01-01

Reliable predictive simulation capability addressing confinement properties in magnetically confined fusion plasmas is critically-important for ITER, a 20 billion dollar international burning plasma device under construction in France. The complex study of kinetic turbulence, which can severely limit the energy confinement and impact the economic viability of fusion systems, requires simulations at extreme scale for such an unprecedented device size. Our newly optimized, global, ab initio particle-in-cell code solving the nonlinear equations underlying gyrokinetic theory achieves excellent performance with respect to "time to solution" at the full capacity of the IBM Blue Gene/Q on 786,432 cores of Mira at ALCFmore » and recently of the 1,572,864 cores of Sequoia at LLNL. Recent multithreading and domain decomposition optimizations in the new GTC-P code represent critically important software advances for modern, low memory per core systems by enabling routine simulations at unprecedented size (130 million grid points ITER-scale) and resolution (65 billion particles).« less

First Observation of Cross-Beam Energy Transfer Mitigation for Direct-Drive Inertial Confinement Fusion Implosions Using Wavelength Detuning at the National Ignition Facility

DOE PAGES

Marozas, J. A.; Hohenberger, M.; Rosenberg, M. J.; ...

2018-02-22

Cross-beam energy transfer (CBET) results from two-beam energy exchange via seeded stimulated Brillouin scattering, which detrimentally reduces ablation pressure and implosion velocity in direct-drive inertial confinement fusion. Direct-drive implosions at the National Ignition Facility were conducted to reduce CBET by detuning the laser-source wavelengths (±2.3 Å UV) of the interacting beams over the equatorial region of the target. For the first time, wavelength detuning was shown to increase the equatorial region velocity experimentally by 16% and to alter the in-flight shell morphology. These experimental observations are consistent with design predictions of radiation–hydrodynamic simulations that indicate a 10% increase in themore » average ablation pressure.« less

First Observation of Cross-Beam Energy Transfer Mitigation for Direct-Drive Inertial Confinement Fusion Implosions Using Wavelength Detuning at the National Ignition Facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Marozas, J. A.; Hohenberger, M.; Rosenberg, M. J.

Cross-beam energy transfer (CBET) results from two-beam energy exchange via seeded stimulated Brillouin scattering, which detrimentally reduces ablation pressure and implosion velocity in direct-drive inertial confinement fusion. Direct-drive implosions at the National Ignition Facility were conducted to reduce CBET by detuning the laser-source wavelengths (±2.3 Å UV) of the interacting beams over the equatorial region of the target. For the first time, wavelength detuning was shown to increase the equatorial region velocity experimentally by 16% and to alter the in-flight shell morphology. These experimental observations are consistent with design predictions of radiation–hydrodynamic simulations that indicate a 10% increase in themore » average ablation pressure.« less

Condorcet and borda count fusion method for ligand-based virtual screening.

PubMed

Ahmed, Ali; Saeed, Faisal; Salim, Naomie; Abdo, Ammar

2014-01-01

It is known that any individual similarity measure will not always give the best recall of active molecule structure for all types of activity classes. Recently, the effectiveness of ligand-based virtual screening approaches can be enhanced by using data fusion. Data fusion can be implemented using two different approaches: group fusion and similarity fusion. Similarity fusion involves searching using multiple similarity measures. The similarity scores, or ranking, for each similarity measure are combined to obtain the final ranking of the compounds in the database. The Condorcet fusion method was examined. This approach combines the outputs of similarity searches from eleven association and distance similarity coefficients, and then the winner measure for each class of molecules, based on Condorcet fusion, was chosen to be the best method of searching. The recall of retrieved active molecules at top 5% and significant test are used to evaluate our proposed method. The MDL drug data report (MDDR), maximum unbiased validation (MUV) and Directory of Useful Decoys (DUD) data sets were used for experiments and were represented by 2D fingerprints. Simulated virtual screening experiments with the standard two data sets show that the use of Condorcet fusion provides a very simple way of improving the ligand-based virtual screening, especially when the active molecules being sought have a lowest degree of structural heterogeneity. However, the effectiveness of the Condorcet fusion was increased slightly when structural sets of high diversity activities were being sought.

Bacillus subtilis spore survival and expression of germination-induced bioluminescence after prolonged incubation under simulated Mars atmospheric pressure and composition: implications for planetary protection and lithopanspermia

NASA Technical Reports Server (NTRS)

Nicholson, Wayne L.; Schuerger, Andrew C.

2005-01-01

Bacterial endospores in the genus Bacillus are considered good models for studying interplanetary transfer of microbes by natural or human processes. Although spore survival during transfer itself has been the subject of considerable study, the fate of spores in extraterrestrial environments has received less attention. In this report we subjected spores of a strain of Bacillus subtilis, containing luciferase resulting from expression of an sspB-luxAB gene fusion, to simulated martian atmospheric pressure (7-18 mbar) and composition (100% CO(2)) for up to 19 days in a Mars simulation chamber. We report here that survival was similar between spores exposed to Earth conditions and spores exposed up to 19 days to simulated martian conditions. However, germination-induced bioluminescence was lower in spores exposed to simulated martian atmosphere, which suggests sublethal impairment of some endogenous spore germination processes.

Negative effect of rapidly resorbing properties of bioactive glass-ceramics as bone graft substitute in a rabbit lumbar fusion model.

PubMed

Lee, Jae Hyup; Ryu, Hyun-Seung; Seo, Jun-Hyuk; Lee, Do-Yoon; Chang, Bong-Soon; Lee, Choon-Ki

2014-03-01

Bioactive glass-ceramics have the ability to directly bind to bones and have been widely used as bone graft substitutes due to their high osteoconductivity and biocompatibility. CaO-SiO2-P2O5-B2O3 glass-ceramics are known to have good osteoconductivity and are used as bone graft extenders. This study aimed to evaluate the effects of the resorbing properties of glass-ceramics in bone fusion after producing and analyzing three types of CaO-SiO2-P2O5-B2O3 glass-ceramics with high osteoconductivity that had enhanced resorption by having an increased B2O3 content. The three types of CaO-SiO2-P2O5-B2O3 glass-ceramics with B2O3 contents of 8.0, 9.0, and 9.5 weight % were designated and grouped as P20B80, P10B90, and P5B95, respectively. Glass-ceramic types were tested for fusion rates and bone formation by employing the lumbar 5-6 intertransverse process fusion model in 51 New Zealand male rabbits. Bioactivity was assessed by soaking in simulated body fluid (SBF). In vitro study results showed sufficient hydroxycarbonate apatite layer formation occurred for P20B80 in1 day, for P10B90 in 3 days, and for P5B95 in 5 days after soaking in SBF. For the rabbit lumbar spine posterolateral fusion model, the autograft group recorded a 100% fusion rate with levels significantly higher than those of P20B80 (29.4%), P10B90 (0%), and P5B95 (14.3%), with high resorbing properties. Resorbing property differences among the three glass-ceramic groups were not significant. Histological results showed new bone formation confirming osteoconductivity in all three types of glass-ceramics. Radiomorphometric results also confirmed the resorbing properties of the three glass-ceramic types. The high resorbing properties and osteoconductivity of porous glass-ceramics can be advantageous as no glass-ceramics remain in the body. However, their relatively fast rate of resorption in the body negatively affects their role as an osteoconductive scaffold as glass-ceramics are resorbed before bony fusion.

Laser program annual report, 1980

DOE Office of Scientific and Technical Information (OSTI.GOV)

Coleman, L.W.; Krupke, W.F.; Strack, J.R.

1981-06-01

Volume 2 contains five sections that cover the areas of target design, target fabrication, diagnostics, and fusion experiments. Section 3 reports on target design activities, plasma theory and simulation, code development, and atomic theory. Section 4 presents the accomplishments of the Target Fabrication Group, Section 5 contains the results of our diagnostics development, and Section 6 describes advances made in the management and analysis of experimental data. Finally, Section 7 in Volume 2 reports the results of laser target experiments conducted during the year.

Validation of Shielding Analysis Capability of SuperMC with SINBAD

NASA Astrophysics Data System (ADS)

Chen, Chaobin; Yang, Qi; Wu, Bin; Han, Yuncheng; Song, Jing

2017-09-01

Abstract: The shielding analysis capability of SuperMC was validated with the Shielding Integral Benchmark Archive Database (SINBAD). The SINBAD was compiled by RSICC and NEA, it includes numerous benchmark experiments performed with the D-T fusion neutron source facilities of OKTAVIAN, FNS, IPPE, etc. The results from SuperMC simulation were compared with experimental data and MCNP results. Very good agreement with deviation lower than 1% was achieved and it suggests that SuperMC is reliable in shielding calculation.

Entropic forces drive self-organization and membrane fusion by SNARE proteins

PubMed Central

Stratton, Benjamin S.; Warner, Jason M.; Rothman, James E.; O’Shaughnessy, Ben

2017-01-01

SNARE proteins are the core of the cell’s fusion machinery and mediate virtually all known intracellular membrane fusion reactions on which exocytosis and trafficking depend. Fusion is catalyzed when vesicle-associated v-SNAREs form trans-SNARE complexes (“SNAREpins”) with target membrane-associated t-SNAREs, a zippering-like process releasing ∼65 kT per SNAREpin. Fusion requires several SNAREpins, but how they cooperate is unknown and reports of the number required vary widely. To capture the collective behavior on the long timescales of fusion, we developed a highly coarse-grained model that retains key biophysical SNARE properties such as the zippering energy landscape and the surface charge distribution. In simulations the ∼65-kT zippering energy was almost entirely dissipated, with fully assembled SNARE motifs but uncomplexed linker domains. The SNAREpins self-organized into a circular cluster at the fusion site, driven by entropic forces that originate in steric–electrostatic interactions among SNAREpins and membranes. Cooperative entropic forces expanded the cluster and pulled the membranes together at the center point with high force. We find that there is no critical number of SNAREs required for fusion, but instead the fusion rate increases rapidly with the number of SNAREpins due to increasing entropic forces. We hypothesize that this principle finds physiological use to boost fusion rates to meet the demanding timescales of neurotransmission, exploiting the large number of v-SNAREs available in synaptic vesicles. Once in an unfettered cluster, we estimate ≥15 SNAREpins are required for fusion within the ∼1-ms timescale of neurotransmitter release. PMID:28490503

Laser Induced Nuclear Fusion, LINF, In Muonic Molecules With Ultrashort Super Intense Laser Fields

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bandrauk, Andre D.; Paramonov, Gennady K.

2010-02-02

Muonium molecules where muons replace electrons increase the stability of molecules to ionization at superhigh intensities, I>10{sup 20} W/cm{sup 2}. We show furthermore from numerical simulations that in the nonsymmetric series, pdu, dtu, ptu, the permanent dipole moments can be used to enhance LINF, Laser Induced Nuclear Fusion by laser induced recollision of the light nucleus with the heavier nucleus.

Study of the fusion point between PM-PCF and panda fiber and its influence to Interferometric fiber-optical gyroscope

NASA Astrophysics Data System (ADS)

Sun, Zuoming; Wang, Shuhua; Li, Junwei

2017-02-01

Microhole collapse property of polarization maintaining photonic crystal fibers (PM-PCF) and its effect on the splice loss and polarization cross-coupling during fusion splicing were investigated. The relationship between the microhole collapse and polarization cross-coupling are analyzed through simulation and experiment. Finally their influence to the phase error of the FOG is calculated and tested.

Synaptobrevin Transmembrane Domain Dimerization Studied by Multiscale Molecular Dynamics Simulations

PubMed Central

Han, Jing; Pluhackova, Kristyna; Wassenaar, Tsjerk A.; Böckmann, Rainer A.

2015-01-01

Synaptic vesicle fusion requires assembly of the SNARE complex composed of SNAP-25, syntaxin-1, and synaptobrevin-2 (sybII) proteins. The SNARE proteins found in vesicle membranes have previously been shown to dimerize via transmembrane (TM) domain interactions. While syntaxin homodimerization is supposed to promote the transition from hemifusion to complete fusion, the role of synaptobrevin’s TM domain association in the fusion process remains poorly understood. Here, we combined coarse-grained and atomistic simulations to model the homodimerization of the sybII transmembrane domain and of selected TM mutants. The wild-type helix is shown to form a stable, right-handed dimer with the most populated helix-helix interface, including key residues predicted in a previous mutagenesis study. In addition, two alternative binding interfaces were discovered, which are essential to explain the experimentally observed higher-order oligomerization of sybII. In contrast, only one dimerization interface was found for a fusion-inactive poly-Leu mutant. Moreover, the association kinetics found for this mutant is lower as compared to the wild-type. These differences in dimerization between the wild-type and the poly-Leu mutant are suggested to be responsible for the reported differences in fusogenic activity between these peptides. This study provides molecular insight into the role of TM sequence specificity for peptide aggregation in membranes. PMID:26287628

Sensor Fusion Based Model for Collision Free Mobile Robot Navigation

PubMed Central

Almasri, Marwah; Elleithy, Khaled; Alajlan, Abrar

2015-01-01

Autonomous mobile robots have become a very popular and interesting topic in the last decade. Each of them are equipped with various types of sensors such as GPS, camera, infrared and ultrasonic sensors. These sensors are used to observe the surrounding environment. However, these sensors sometimes fail and have inaccurate readings. Therefore, the integration of sensor fusion will help to solve this dilemma and enhance the overall performance. This paper presents a collision free mobile robot navigation based on the fuzzy logic fusion model. Eight distance sensors and a range finder camera are used for the collision avoidance approach where three ground sensors are used for the line or path following approach. The fuzzy system is composed of nine inputs which are the eight distance sensors and the camera, two outputs which are the left and right velocities of the mobile robot’s wheels, and 24 fuzzy rules for the robot’s movement. Webots Pro simulator is used for modeling the environment and the robot. The proposed methodology, which includes the collision avoidance based on fuzzy logic fusion model and line following robot, has been implemented and tested through simulation and real time experiments. Various scenarios have been presented with static and dynamic obstacles using one robot and two robots while avoiding obstacles in different shapes and sizes. PMID:26712766

Sensor Fusion Based Model for Collision Free Mobile Robot Navigation.

PubMed

Almasri, Marwah; Elleithy, Khaled; Alajlan, Abrar

2015-12-26

Autonomous mobile robots have become a very popular and interesting topic in the last decade. Each of them are equipped with various types of sensors such as GPS, camera, infrared and ultrasonic sensors. These sensors are used to observe the surrounding environment. However, these sensors sometimes fail and have inaccurate readings. Therefore, the integration of sensor fusion will help to solve this dilemma and enhance the overall performance. This paper presents a collision free mobile robot navigation based on the fuzzy logic fusion model. Eight distance sensors and a range finder camera are used for the collision avoidance approach where three ground sensors are used for the line or path following approach. The fuzzy system is composed of nine inputs which are the eight distance sensors and the camera, two outputs which are the left and right velocities of the mobile robot's wheels, and 24 fuzzy rules for the robot's movement. Webots Pro simulator is used for modeling the environment and the robot. The proposed methodology, which includes the collision avoidance based on fuzzy logic fusion model and line following robot, has been implemented and tested through simulation and real time experiments. Various scenarios have been presented with static and dynamic obstacles using one robot and two robots while avoiding obstacles in different shapes and sizes.

Embry-Riddle Aeronautical University multispectral sensor and data fusion laboratory: a model for distributed research and education

NASA Astrophysics Data System (ADS)

McMullen, Sonya A. H.; Henderson, Troy; Ison, David

2017-05-01

The miniaturization of unmanned systems and spacecraft, as well as computing and sensor technologies, has opened new opportunities in the areas of remote sensing and multi-sensor data fusion for a variety of applications. Remote sensing and data fusion historically have been the purview of large government organizations, such as the Department of Defense (DoD), National Aeronautics and Space Administration (NASA), and National Geospatial-Intelligence Agency (NGA) due to the high cost and complexity of developing, fielding, and operating such systems. However, miniaturized computers with high capacity processing capabilities, small and affordable sensors, and emerging, commercially available platforms such as UAS and CubeSats to carry such sensors, have allowed for a vast range of novel applications. In order to leverage these developments, Embry-Riddle Aeronautical University (ERAU) has developed an advanced sensor and data fusion laboratory to research component capabilities and their employment on a wide-range of autonomous, robotic, and transportation systems. This lab is unique in several ways, for example, it provides a traditional campus laboratory for students and faculty to model and test sensors in a range of scenarios, process multi-sensor data sets (both simulated and experimental), and analyze results. Moreover, such allows for "virtual" modeling, testing, and teaching capability reaching beyond the physical confines of the facility for use among ERAU Worldwide students and faculty located around the globe. Although other institutions such as Georgia Institute of Technology, Lockheed Martin, University of Dayton, and University of Central Florida have optical sensor laboratories, the ERAU virtual concept is the first such lab to expand to multispectral sensors and data fusion, while focusing on the data collection and data products and not on the manufacturing aspect. Further, the initiative is a unique effort among Embry-Riddle faculty to develop multi-disciplinary, cross-campus research to facilitate faculty- and student-driven research. Specifically, the ERAU Worldwide Campus, with locations across the globe and delivering curricula online, will be leveraged to provide novel approaches to remote sensor experimentation and simulation. The purpose of this paper and presentation is to present this new laboratory, research, education, and collaboration process.

Computed tomography-magnetic resonance image fusion: a clinical evaluation of an innovative approach for improved tumor localization in primary central nervous system lesions.

PubMed

Lattanzi, J P; Fein, D A; McNeeley, S W; Shaer, A H; Movsas, B; Hanks, G E

1997-01-01

We describe our initial experience with the AcQSim (Picker International, St. David, PA) computed tomography-magnetic resonance imaging (CT-MRI) fusion software in eight patients with intracranial lesions. MRI data are electronically integrated into the CT-based treatment planning system. Since MRI is superior to CT in identifying intracranial abnormalities, we evaluated the precision and feasibility of this new localization method. Patients initially underwent CT simulation from C2 to the most superior portion of the scalp. T2 and post-contrast T1-weighted MRI of this area was then performed. Patient positioning was duplicated utilizing a head cup and bridge of nose to forehead angle measurements. First, a gross tumor volume (GTV) was identified utilizing the CT (CT/GTV). The CT and MRI scans were subsequently fused utilizing a point pair matching method and a second GTV (CT-MRI/GTV) was contoured with the aid of both studies. The fusion process was uncomplicated and completed in a timely manner. Volumetric analysis revealed the CT-MRI/GTV to be larger than the CT/GTV in all eight cases. The mean CT-MRI/GTV was 28.7 cm3 compared to 16.7 cm3 by CT alone. This translated into a 72% increase in the radiographic tumor volume by CT-MRI. A simulated dose-volume histogram in two patients revealed that marginal portions of the lesion, as identified by CT and MRI, were not included in the high dose treatment volume as contoured with the use of CT alone. Our initial experience with the fusion software demonstrated an improvement in tumor localization with this technique. Based on these patients the use of CT alone for treatment planning purposes in central nervous system (CNS) lesions is inadequate and would result in an unacceptable rate of marginal misses. The importation of MRI data into three-dimensional treatment planning is therefore crucial to accurate tumor localization. The fusion process simplifies and improves precision of this task.

Z-Pinch Fusion Propulsion

NASA Technical Reports Server (NTRS)

Miernik, Janie

2011-01-01

Fusion-based nuclear propulsion has the potential to enable fast interplanetary transportation. Shorter trips are better for humans in the harmful radiation environment of deep space. Nuclear propulsion and power plants can enable high Ispand payload mass fractions because they require less fuel mass. Fusion energy research has characterized the Z-Pinch dense plasma focus method. (1) Lightning is form of pinched plasma electrical discharge phenomena. (2) Wire array Z-Pinch experiments are commonly studied and nuclear power plant configurations have been proposed. (3) Used in the field of Nuclear Weapons Effects (NWE) testing in the defense industry, nuclear weapon x-rays are simulated through Z-Pinch phenomena.

Demonstration of radiation pulse shaping with nested-tungsten-wire-array pinches for high-yield inertial confinement fusion.

PubMed

Cuneo, M E; Vesey, R A; Sinars, D B; Chittenden, J P; Waisman, E M; Lemke, R W; Lebedev, S V; Bliss, D E; Stygar, W A; Porter, J L; Schroen, D G; Mazarakis, M G; Chandler, G A; Mehlhorn, T A

2005-10-28

Nested wire-array pinches are shown to generate soft x-ray radiation pulse shapes required for three-shock isentropic compression and hot-spot ignition of high-yield inertial confinement fusion capsules. We demonstrate a reproducible and tunable foot pulse (first shock) produced by interaction of the outer and inner arrays. A first-step pulse (second shock) is produced by inner array collision with a central CH2 foam target. Stagnation of the inner array at the axis produces the third shock. Capsules optimized for several of these shapes produce 290-900 MJ fusion yields in 1D simulations.

Multimodal Fusion with Reference: Searching for Joint Neuromarkers of Working Memory Deficits in Schizophrenia

PubMed Central

Qi, Shile; Calhoun, Vince D.; van Erp, Theo G. M.; Bustillo, Juan; Damaraju, Eswar; Turner, Jessica A.; Du, Yuhui; Chen, Jiayu; Yu, Qingbao; Mathalon, Daniel H.; Ford, Judith M.; Voyvodic, James; Mueller, Bryon A.; Belger, Aysenil; Ewen, Sarah Mc; Potkin, Steven G.; Preda, Adrian; Jiang, Tianzi

2017-01-01

Multimodal fusion is an effective approach to take advantage of cross-information among multiple imaging data to better understand brain diseases. However, most current fusion approaches are blind, without adopting any prior information. To date, there is increasing interest to uncover the neurocognitive mapping of specific behavioral measurement on enriched brain imaging data; hence, a supervised, goal-directed model that enables a priori information as a reference to guide multimodal data fusion is in need and a natural option. Here we proposed a fusion with reference model, called “multi-site canonical correlation analysis with reference plus joint independent component analysis” (MCCAR+jICA), which can precisely identify co-varying multimodal imaging patterns closely related to reference information, such as cognitive scores. In a 3-way fusion simulation, the proposed method was compared with its alternatives on estimation accuracy of both target component decomposition and modality linkage detection. MCCAR+jICA outperforms others with higher precision. In human imaging data, working memory performance was utilized as a reference to investigate the covarying functional and structural brain patterns among 3 modalities and how they are impaired in schizophrenia. Two independent cohorts (294 and 83 subjects respectively) were used. Interestingly, similar brain maps were identified between the two cohorts, with substantial overlap in the executive control networks in fMRI, salience network in sMRI, and major white matter tracts in dMRI. These regions have been linked with working memory deficits in schizophrenia in multiple reports, while MCCAR+jICA further verified them in a repeatable, joint manner, demonstrating the potential of such results to identify potential neuromarkers for mental disorders. PMID:28708547

Conceptual design of a fast-ignition laser fusion reactor based on a dry wall chamber

NASA Astrophysics Data System (ADS)

Ogawa, Y.; Goto, T.; Okano, K.; Asaoka, Y.; Hiwatari, R.; Someya, Y.

2008-05-01

The fast ignition is quite attractive for a compact laser fusion reactor, because a sufficiently high pellet gain is available with a small input energy. We designed an inertial fusion reactor based on Fast-ignition Advanced Laser fusion reactor CONcept, called FALCON-D, where a dry wall is employed for a chamber wall. A simple point model shows that the pellet gain G~100 is available with laser energies of 350kJ for implosion, 50kJ for heating. This results in the fusion yield of 40 MJ in one shot. By increasing the repetition rate up to 30 Hz, the fusion power of 1.2 GWth becomes available. Plant system analysis shows the net electric power to be about 0.4 GWe In the fast ignition it is available to employ a low aspect ratio pellet, which is favorable for the stability during the implosion phase. Here the pellet aspect ratio is reduced to be 2 ~ 4, and the optimization of the pulse shape for the implosion laser are carried out by using the 1-D hydrodynamic simulation code ILESTA-1D. A ferritic steel with a tungsten armour is employed for the chamber wall. The feasibility of this dry wall concept is studied from various engineering aspects such as surface melting, physical and chemical sputtering, blistering and exfoliation by helium retention, and thermo-mechanical fatigue, and it is found that blistering and exfoliation due to the helium retention and fatigue failure due to cyclic thermal load are major concerns. The cost analysis shows that the construction cost is moderate but the cost of electricity is slightly expensive.

Biomechanics of Hybrid Anterior Cervical Fusion and Artificial Disc Replacement in 3-Level Constructs: An In Vitro Investigation.

PubMed

Liao, Zhenhua; Fogel, Guy R; Pu, Ting; Gu, Hongsheng; Liu, Weiqiang

2015-11-03

The ideal surgical approach for cervical disk disease remains controversial, especially for multilevel cervical disease. The purpose of this study was to investigate the biomechanics of the cervical spine after 3-level hybrid surgery compared with 3-level anterior cervical discectomy and fusion (ACDF). Eighteen human cadaveric spines (C2-T1) were evaluated under displacement-input protocol. After intact testing, a simulated hybrid construct or fusion construct was created between C3 to C6 and tested in the following 3 conditions: 3-level disc plate disc (3DPD), 3-level plate disc plate (3PDP), and 3-level plate (3P). Compared to intact, almost 65~80% of motion was successfully restricted at C3-C6 fusion levels (p<0.05). 3DPD construct resulted in slight increase at the 3 instrumented levels (p>0.05). 3PDP construct resulted in significant decrease of ROM at C3-C6 levels less than 3P (p<0.05). Both 3DPD and 3PDP caused significant reduction of ROM at the arthrodesis level and produced motion increase at the arthroplasty level. For adjacent levels, 3P resulted in markedly increased contribution of both upper and lower adjacent levels (p<0.05). Significant motion increases lower than 3P were only noted at partly adjacent levels in some conditions for 3DPD and 3PDP (p<0.05). ACDF eliminated motion within the construct and greatly increased adjacent motion. Artificial cervical disc replacement normalized motion of its segment and adjacent segments. While hybrid conditions failed to restore normal motion within the construct, they significantly normalized motion in adjacent segments compared with the 3-level ACDF condition. The artificial disc in 3-level constructs has biomechanical advantages compared to fusion in normalizing motion.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Temporal, Mauro; Canaud, Benoit; Cayzac, Witold

The alpha-particle energy deposition mechanism modifies the ignition conditions of the thermonuclear Deuterium-Tritium fusion reactions, and constitutes a key issue in achieving high gain in Inertial Confinement Fusion implosions. One-dimensional hydrodynamic calculations have been performed with the code Multi-IFE to simulate the implosion of a capsule directly irradiated by a laser beam. The diffusion approximation for the alpha energy deposition has been used to optimize three laser profiles corresponding to different implosion velocities. A Monte-Carlo package has been included in Multi-IFE to calculate the alpha energy transport, and in this case the energy deposition uses both the LP and themore » BPS stopping power models. Homothetic transformations that maintain a constant implosion velocity have been used to map out the transition region between marginally-igniting and high-gain configurations. Furthermore, the results provided by the two models have been compared and it is found that – close to the ignition threshold – in order to produce the same fusion energy, the calculations performed with the BPS model require about 10% more invested energy with respect to the LP model.« less

Development of the dense plasma focus for short-pulse applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bennett, N.; Blasco, M.; Breeding, K.

The dense plasma focus (DPF) has long been considered a compact source for pulsed neutrons and has traditionally been optimized for the total neutron yield. Here, we describe the efforts to optimize the DPF for short-pulse applications by introducing a reentrant cathode at the end of the coaxial plasma gun. We reduced the resulting neutron pulse widths by an average of 21±921±9% from the traditional long-drift DPF design. Pulse widths and yields achieved from deuterium-tritium fusion at 2 MA are 61.8±30.761.8±30.7 ns FWHM and 1.84±0.49×10121.84±0.49×10 12 neutrons per shot. Simulations were conducted concurrently to elucidate the DPF operation and confirmmore » the role of the reentrant cathode. Furthermore, a hybrid fluid-kinetic particle-in-cell modeling capability demonstrates correct sheath velocities, plasma instabilities, and fusion yield rates. Consistent with previous findings that the DPF is dominated by beam-target fusion from superthermal ions, we estimate that the thermonuclear contribution is at the 1% level.« less

Development of the dense plasma focus for short-pulse applications

DOE PAGES

Bennett, N.; Blasco, M.; Breeding, K.; ...

2017-01-05

The dense plasma focus (DPF) has long been considered a compact source for pulsed neutrons and has traditionally been optimized for the total neutron yield. Here, we describe the efforts to optimize the DPF for short-pulse applications by introducing a reentrant cathode at the end of the coaxial plasma gun. We reduced the resulting neutron pulse widths by an average of 21±921±9% from the traditional long-drift DPF design. Pulse widths and yields achieved from deuterium-tritium fusion at 2 MA are 61.8±30.761.8±30.7 ns FWHM and 1.84±0.49×10121.84±0.49×10 12 neutrons per shot. Simulations were conducted concurrently to elucidate the DPF operation and confirmmore » the role of the reentrant cathode. Furthermore, a hybrid fluid-kinetic particle-in-cell modeling capability demonstrates correct sheath velocities, plasma instabilities, and fusion yield rates. Consistent with previous findings that the DPF is dominated by beam-target fusion from superthermal ions, we estimate that the thermonuclear contribution is at the 1% level.« less

Fusion-neutron-yield, activation measurements at the Z accelerator: design, analysis, and sensitivity.

PubMed

Hahn, K D; Cooper, G W; Ruiz, C L; Fehl, D L; Chandler, G A; Knapp, P F; Leeper, R J; Nelson, A J; Smelser, R M; Torres, J A

2014-04-01

We present a general methodology to determine the diagnostic sensitivity that is directly applicable to neutron-activation diagnostics fielded on a wide variety of neutron-producing experiments, which include inertial-confinement fusion (ICF), dense plasma focus, and ion beam-driven concepts. This approach includes a combination of several effects: (1) non-isotropic neutron emission; (2) the 1/r(2) decrease in neutron fluence in the activation material; (3) the spatially distributed neutron scattering, attenuation, and energy losses due to the fielding environment and activation material itself; and (4) temporally varying neutron emission. As an example, we describe the copper-activation diagnostic used to measure secondary deuterium-tritium fusion-neutron yields on ICF experiments conducted on the pulsed-power Z Accelerator at Sandia National Laboratories. Using this methodology along with results from absolute calibrations and Monte Carlo simulations, we find that for the diagnostic configuration on Z, the diagnostic sensitivity is 0.037% ± 17% counts/neutron per cm(2) and is ∼ 40% less sensitive than it would be in an ideal geometry due to neutron attenuation, scattering, and energy-loss effects.

TANDI: threat assessment of network data and information

NASA Astrophysics Data System (ADS)

Holsopple, Jared; Yang, Shanchieh Jay; Sudit, Moises

2006-04-01

Current practice for combating cyber attacks typically use Intrusion Detection Sensors (IDSs) to passively detect and block multi-stage attacks. This work leverages Level-2 fusion that correlates IDS alerts belonging to the same attacker, and proposes a threat assessment algorithm to predict potential future attacker actions. The algorithm, TANDI, reduces the problem complexity by separating the models of the attacker's capability and opportunity, and fuse the two to determine the attacker's intent. Unlike traditional Bayesian-based approaches, which require assigning a large number of edge probabilities, the proposed Level-3 fusion procedure uses only 4 parameters. TANDI has been implemented and tested with randomly created attack sequences. The results demonstrate that TANDI predicts future attack actions accurately as long as the attack is not part of a coordinated attack and contains no insider threats. In the presence of abnormal attack events, TANDI will alarm the network analyst for further analysis. The attempt to evaluate a threat assessment algorithm via simulation is the first in the literature, and shall open up a new avenue in the area of high level fusion.

One-dimensional MHD simulations of MTF systems with compact toroid targets and spherical liners

NASA Astrophysics Data System (ADS)

Khalzov, Ivan; Zindler, Ryan; Barsky, Sandra; Delage, Michael; Laberge, Michel

2017-10-01

One-dimensional (1D) MHD code is developed in General Fusion (GF) for coupled plasma-liner simulations in magnetized target fusion (MTF) systems. The main goal of these simulations is to search for optimal parameters of MTF reactor, in which spherical liquid metal liner compresses compact toroid plasma. The code uses Lagrangian description for both liner and plasma. The liner is represented as a set of spherical shells with fixed masses while plasma is discretized as a set of nested tori with circular cross sections and fixed number of particles between them. All physical fields are 1D functions of either spherical (liner) or small toroidal (plasma) radius. Motion of liner and plasma shells is calculated self-consistently based on applied forces and equations of state. Magnetic field is determined by 1D profiles of poloidal and toroidal fluxes - they are advected with shells and diffuse according to local resistivity, this also accounts for flux leakage into the liner. Different plasma transport models are implemented, this allows for comparison with ongoing GF experiments. Fusion power calculation is included into the code. We performed a series of parameter scans in order to establish the underlying dependencies of the MTF system and find the optimal reactor design point.

MagLIF scaling on Z and future machines

NASA Astrophysics Data System (ADS)

Slutz, Stephen; Stygar, William; Gomez, Matthew; Campbell, Edward; Peterson, Kyle; Sefkow, Adam; Sinars, Daniel; Vesey, Roger

2015-11-01

The MagLIF (Magnetized Liner Inertial Fusion) concept [S.A. Slutz et al Phys. Plasmas 17, 056303, 2010] has demonstrated [M.R. Gomez et al., PRL 113, 155003, 2014] fusion-relevant plasma conditions on the Z machine. We present 2D numerical simulations of the scaling of MagLIF on Z indicating that deuterium/tritium (DT) fusion yields greater than 100 kJ could be possible on Z when operated at a peak current of 25 MA. Much higher yields are predicted for MagLIF driven with larger peak currents. Two high performance pulsed-power machines (Z300 and Z800) have been designed based on Linear Transformer Driver (LTD) technology. The Z300 design would provide approximately 48 MA to a MagLIF load, while Z800 would provide about 66 MA. We used a parameterized Thevenin equivalent circuit to drive a series of 1D and 2D numerical simulations with currents between and beyond these two designs. Our simulations indicate that 5-10 MJ yields may be possible with Z300, while yields of about 1 GJ may be possible with Z800. Sandia is a multiprogram laboratory operated by Sandia Corporation, a Lockheed Martin Company, for the United States Department of Energy's National Nuclear Security Administration under contract DE-AC04-94AL85000.

Global two-fluid simulations of geodesic acoustic modes in strongly shaped tight aspect ratio tokamak plasmas

DOE Office of Scientific and Technical Information (OSTI.GOV)

Robinson, J. R.; Hnat, B.; Thyagaraja, A.

2013-05-15

Following recent observations suggesting the presence of the geodesic acoustic mode (GAM) in ohmically heated discharges in the Mega Amp Spherical Tokamak (MAST) [J. R. Robinson et al., Plasma Phys. Controlled Fusion 54, 105007 (2012)], the behaviour of the GAM is studied numerically using the two fluid, global code CENTORI [P. J. Knight et al. Comput. Phys. Commun. 183, 2346 (2012)]. We examine mode localisation and effects of magnetic geometry, given by aspect ratio, elongation, and safety factor, on the observed frequency of the mode. An excellent agreement between simulations and experimental data is found for simulation plasma parameters matchedmore » to those of MAST. Increasing aspect ratio yields good agreement between the GAM frequency found in the simulations and an analytical result obtained for elongated large aspect ratio plasmas.« less

Computer modeling and simulation in inertial confinement fusion

DOE Office of Scientific and Technical Information (OSTI.GOV)

McCrory, R.L.; Verdon, C.P.

1989-03-01

The complex hydrodynamic and transport processes associated with the implosion of an inertial confinement fusion (ICF) pellet place considerable demands on numerical simulation programs. Processes associated with implosion can usually be described using relatively simple models, but their complex interplay requires that programs model most of the relevant physical phenomena accurately. Most hydrodynamic codes used in ICF incorporate a one-fluid, two-temperature model. Electrons and ions are assumed to flow as one fluid (no charge separation). Due to the relatively weak coupling between the ions and electrons, each species is treated separately in terms of its temperature. In this paper wemore » describe some of the major components associated with an ICF hydrodynamics simulation code. To serve as an example we draw heavily on a two-dimensional Lagrangian hydrodynamic code (ORCHID) written at the University of Rochester's Laboratory for Laser Energetics. 46 refs., 19 figs., 1 tab.« less

Characterization of a deuterium-deuterium plasma fusion neutron generator

NASA Astrophysics Data System (ADS)

Lang, R. F.; Pienaar, J.; Hogenbirk, E.; Masson, D.; Nolte, R.; Zimbal, A.; Röttger, S.; Benabderrahmane, M. L.; Bruno, G.

2018-01-01

We characterize the neutron output of a deuterium-deuterium plasma fusion neutron generator, model 35-DD-W-S, manufactured by NSD/Gradel-Fusion. The measured energy spectrum is found to be dominated by neutron peaks at 2.2 MeV and 2.7 MeV. A detailed GEANT4 simulation accurately reproduces the measured energy spectrum and confirms our understanding of the fusion process in this generator. Additionally, a contribution of 14 . 1 MeV neutrons from deuterium-tritium fusion is found at a level of 3 . 5%, from tritium produced in previous deuterium-deuterium reactions. We have measured both the absolute neutron flux as well as its relative variation on the operational parameters of the generator. We find the flux to be proportional to voltage V 3 . 32 ± 0 . 14 and current I 0 . 97 ± 0 . 01. Further, we have measured the angular dependence of the neutron emission with respect to the polar angle. We conclude that it is well described by isotropic production of neutrons within the cathode field cage.

Nuclear fusion driven by Coulomb explosion of homonuclear and heteronuclear deuterium- and tritium-containing clusters

NASA Astrophysics Data System (ADS)

Last, Isidore; Jortner, Joshua

2001-12-01

The ionization and Coulomb explosion of homonuclear Dn and Tn (n=959-8007) and heteronuclear (D2O)n and (T2O)n (n=459-2171) clusters in very intense (I=5×1014-5×1018 W cm-2) laser fields is studied using classical dynamics simulations. The efficiency of the d+d and d+t nuclear fusion driven by the Coulomb explosion (NFDCE) is explored. The d+d NFDCE of (D2O)n heteronuclear clusters is enhanced by energetic and kinematic effects for D+, while for (T2O)n heteronuclear clusters the kinetic energy of T+ is dominated by energetic effects. The cluster size dependence of the fusion reaction yield has been established. The heteronuclear clusters provide considerably higher d+d and d+t fusion reaction yields than the homonuclear clusters of the same size. The clusters consisting of both D and T atoms can provide highly efficient d+t fusion reactions.

Numerical study of the current-convective instability driven by asymmetry of detachment in inner and outer divertors

NASA Astrophysics Data System (ADS)

Stepanenko, A. A.; Krasheninnikov, S. I.

2018-01-01

One of the possible mechanisms responsible for strong radiation fluctuations observed in recent experiments with detached plasmas at ASDEX Upgrade [Potzel et al., Nucl. Fusion 54, 013001 (2014)] can be related to the onset of the current-convective instability (CCI) driven by strong asymmetry of detachment in the inner and outer divertors of the tokamak [S. Krasheninnikov and A. Smolyakov, Phys. Plasmas 23, 092505 (2016)]. In this study, we present the physical model, used to simulate the CCI, and the first numerical results of modeling of the CCI dynamics in ASDEX Upgrade-like conditions. The simulation results provide frequency spectra of turbulent divertor plasma oscillations showing reasonably good agreement with the available experimental data.

Fission and fusion scenarios for magnetic microswimmer clusters

PubMed Central

Guzmán-Lastra, Francisca; Kaiser, Andreas; Löwen, Hartmut

2016-01-01

Fission and fusion processes of particle clusters occur in many areas of physics and chemistry from subnuclear to astronomic length scales. Here we study fission and fusion of magnetic microswimmer clusters as governed by their hydrodynamic and dipolar interactions. Rich scenarios are found that depend crucially on whether the swimmer is a pusher or a puller. In particular a linear magnetic chain of pullers is stable while a pusher chain shows a cascade of fission (or disassembly) processes as the self-propulsion velocity is increased. Contrarily, magnetic ring clusters show fission for any type of swimmer. Moreover, we find a plethora of possible fusion (or assembly) scenarios if a single swimmer collides with a ringlike cluster and two rings spontaneously collide. Our predictions are obtained by computer simulations and verifiable in experiments on active colloidal Janus particles and magnetotactic bacteria. PMID:27874006

Measuring implosion velocities in experiments and simulations of laser-driven cylindrical implosions on the OMEGA laser

NASA Astrophysics Data System (ADS)

Hansen, E. C.; Barnak, D. H.; Betti, R.; Campbell, E. M.; Chang, P.-Y.; Davies, J. R.; Glebov, V. Yu; Knauer, J. P.; Peebles, J.; Regan, S. P.; Sefkow, A. B.

2018-05-01

Laser-driven magnetized liner inertial fusion (MagLIF) on OMEGA involves cylindrical implosions, a preheat beam, and an applied magnetic field. Initial experiments excluded the preheat beam and magnetic field to better characterize the implosion. X-ray self-emission as measured by framing cameras was used to determine the shell trajectory. The 1D code LILAC was used to model the central region of the implosion, and results were compared to 2D simulations from the HYDRA code. Post-processing of simulation output with SPECT3D and Yorick produced synthetic x-ray images that were used to compare the simulation results with the x-ray framing camera data. Quantitative analysis shows that higher measured neutron yields correlate with higher implosion velocities. The future goal is to further analyze the x-ray images to characterize the uniformity of the implosions and apply these analysis techniques to integrated laser-driven MagLIF shots to better understand the effects of preheat and the magnetic field.

ORNL Cray X1 evaluation status report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Agarwal, P.K.; Alexander, R.A.; Apra, E.

2004-05-01

On August 15, 2002 the Department of Energy (DOE) selected the Center for Computational Sciences (CCS) at Oak Ridge National Laboratory (ORNL) to deploy a new scalable vector supercomputer architecture for solving important scientific problems in climate, fusion, biology, nanoscale materials and astrophysics. ''This program is one of the first steps in an initiative designed to provide U.S. scientists with the computational power that is essential to 21st century scientific leadership,'' said Dr. Raymond L. Orbach, director of the department's Office of Science. In FY03, CCS procured a 256-processor Cray X1 to evaluate the processors, memory subsystem, scalability of themore » architecture, software environment and to predict the expected sustained performance on key DOE applications codes. The results of the micro-benchmarks and kernel bench marks show the architecture of the Cray X1 to be exceptionally fast for most operations. The best results are shown on large problems, where it is not possible to fit the entire problem into the cache of the processors. These large problems are exactly the types of problems that are important for the DOE and ultra-scale simulation. Application performance is found to be markedly improved by this architecture: - Large-scale simulations of high-temperature superconductors run 25 times faster than on an IBM Power4 cluster using the same number of processors. - Best performance of the parallel ocean program (POP v1.4.3) is 50 percent higher than on Japan s Earth Simulator and 5 times higher than on an IBM Power4 cluster. - A fusion application, global GYRO transport, was found to be 16 times faster on the X1 than on an IBM Power3. The increased performance allowed simulations to fully resolve questions raised by a prior study. - The transport kernel in the AGILE-BOLTZTRAN astrophysics code runs 15 times faster than on an IBM Power4 cluster using the same number of processors. - Molecular dynamics simulations related to the phenomenon of photon echo run 8 times faster than previously achieved. Even at 256 processors, the Cray X1 system is already outperforming other supercomputers with thousands of processors for a certain class of applications such as climate modeling and some fusion applications. This evaluation is the outcome of a number of meetings with both high-performance computing (HPC) system vendors and application experts over the past 9 months and has received broad-based support from the scientific community and other agencies.« less

Yield degradation in inertial-confinement-fusion implosions due to shock-driven kinetic fuel-species stratification and viscous heating

DOE PAGES

Taitano, William T.; Simakov, Andrei N.; Chacon, Luis; ...

2018-04-09

Anomalous thermonuclear yield degradation (i.e., that not describable by single-fluid radiation hydrodynamics) in Inertial Confinement Fusion (ICF) implosions is ubiquitously observed in both Omega and National Ignition experiments. Multiple experimental and theoretical studies have been carried out to investigate the origin of such a degradation. Relative concentration changes of fuel-ion species, as well as kinetically enhanced viscous heating, have been among possible explanations proposed for certain classes of ICF experiments. In this study, we investigate the role of such kinetic plasma effects in detail. To this end, we use the iFP code to perform multi-species ion Vlasov-Fokker-Planck simulations of ICFmore » capsule implosions with the fuel comprising various hydrodynamically equivalent mixtures of deuterium (D) and helium-3 (3He), as in the original. We employ the same computational setup as in O. Larroche, which was the first to simulate the experiments kinetically. However, unlike the Larroche study, and in partial agreement with experimental data, we find a systematic yield degradation in multi-species simulations versus averaged-ion simulations when the D-fuel fraction is decreased. This yield degradation originates in the fuel-ion species stratification induced by plasma shocks, which imprints the imploding system and results in the relocation of the D ions from the core of the capsule to its periphery, thereby reducing the yield relative to a non-separable averaged-ion case. By comparing yields from the averaged-ion kinetic simulations and from the hydrodynamic scaling, we also observe yield variations associated with ion kinetic effects other than fuel-ion stratification, such as ion viscous heating, which is typically neglected in hydrodynamic implosions' simulations. Since our kinetic simulations are driven by hydrodynamic boundary conditions at the fuel-ablator interface, they cannot capture the effects of ion viscosity on the capsule compression, or effects associated with the interface, which are expected to be important. As a result, studies of such effects are left for future work.« less

Yield degradation in inertial-confinement-fusion implosions due to shock-driven kinetic fuel-species stratification and viscous heating

DOE Office of Scientific and Technical Information (OSTI.GOV)

Taitano, William T.; Simakov, Andrei N.; Chacon, Luis

Anomalous thermonuclear yield degradation (i.e., that not describable by single-fluid radiation hydrodynamics) in Inertial Confinement Fusion (ICF) implosions is ubiquitously observed in both Omega and National Ignition experiments. Multiple experimental and theoretical studies have been carried out to investigate the origin of such a degradation. Relative concentration changes of fuel-ion species, as well as kinetically enhanced viscous heating, have been among possible explanations proposed for certain classes of ICF experiments. In this study, we investigate the role of such kinetic plasma effects in detail. To this end, we use the iFP code to perform multi-species ion Vlasov-Fokker-Planck simulations of ICFmore » capsule implosions with the fuel comprising various hydrodynamically equivalent mixtures of deuterium (D) and helium-3 (3He), as in the original. We employ the same computational setup as in O. Larroche, which was the first to simulate the experiments kinetically. However, unlike the Larroche study, and in partial agreement with experimental data, we find a systematic yield degradation in multi-species simulations versus averaged-ion simulations when the D-fuel fraction is decreased. This yield degradation originates in the fuel-ion species stratification induced by plasma shocks, which imprints the imploding system and results in the relocation of the D ions from the core of the capsule to its periphery, thereby reducing the yield relative to a non-separable averaged-ion case. By comparing yields from the averaged-ion kinetic simulations and from the hydrodynamic scaling, we also observe yield variations associated with ion kinetic effects other than fuel-ion stratification, such as ion viscous heating, which is typically neglected in hydrodynamic implosions' simulations. Since our kinetic simulations are driven by hydrodynamic boundary conditions at the fuel-ablator interface, they cannot capture the effects of ion viscosity on the capsule compression, or effects associated with the interface, which are expected to be important. As a result, studies of such effects are left for future work.« less

Proceedings of the Augmented VIsual Display (AVID) Research Workshop

NASA Technical Reports Server (NTRS)

Kaiser, Mary K. (Editor); Sweet, Barbara T. (Editor)

1993-01-01

The papers, abstracts, and presentations were presented at a three day workshop focused on sensor modeling and simulation, and image enhancement, processing, and fusion. The technical sessions emphasized how sensor technology can be used to create visual imagery adequate for aircraft control and operations. Participants from industry, government, and academic laboratories contributed to panels on Sensor Systems, Sensor Modeling, Sensor Fusion, Image Processing (Computer and Human Vision), and Image Evaluation and Metrics.

Simulation of RF-fields in a fusion device

DOE Office of Scientific and Technical Information (OSTI.GOV)

De Witte, Dieter; Bogaert, Ignace; De Zutter, Daniel

2009-11-26

In this paper the problem of scattering off a fusion plasma is approached from the point of view of integral equations. Using the volume equivalence principle an integral equation is derived which describes the electromagnetic fields in a plasma. The equation is discretized with MoM using conforming basis functions. This reduces the problem to solving a dense matrix equation. This can be done iteratively. Each iteration can be sped up using FFTs.

Investigating inertial confinement fusion target fuel conditions through x-ray spectroscopya)

NASA Astrophysics Data System (ADS)

Hansen, Stephanie B.

2012-05-01

Inertial confinement fusion (ICF) targets are designed to produce hot, dense fuel in a neutron-producing core that is surrounded by a shell of compressing material. The x-rays emitted from ICF plasmas can be analyzed to reveal details of the temperatures, densities, gradients, velocities, and mix characteristics of ICF targets. Such diagnostics are critical to understand the target performance and to improve the predictive power of simulation codes.

Time-dependent modeling of dust injection in semi-detached ITER divertor plasma

NASA Astrophysics Data System (ADS)

Smirnov, Roman; Krasheninnikov, Sergei

2017-10-01

At present, it is generally understood that dust related issues will play important role in operation of the next step fusion devices, i.e. ITER, and in the development of future fusion reactors. Recent progress in research on dust in magnetic fusion devises has outlined several topics of particular concern: a) degradation of fusion plasma performance; b) impairment of in-vessel diagnostic instruments; and c) safety issues related to dust reactivity and tritium retention. In addition, observed dust events in fusion edge plasmas are highly irregular and require consideration of temporal evolution of both the dust and the fusion plasma. In order to address the dust-related fusion performance issues, we have coupled the dust transport code DUSTT and the edge plasma transport code UEDGE in time-dependent manner, allowing modeling of transient dust-induced phenomena in fusion edge plasmas. Using the coupled codes we simulate burst-like injection of tungsten dust into ITER divertor plasma in semi-detached regime, which is considered as preferable ITER divertor operational mode based on the plasma and heat load control restrictions. Analysis of transport of the dust and the dust-produced impurities, and of dynamics of the ITER divertor and edge plasma in response to the dust injection will be presented. This material is based upon work supported by the U.S. Department of Energy, Office of Science, Office of Fusion Energy Sciences, under Award Number DE-FG02-06ER54852.

EDITORIAL: Plasma Surface Interactions for Fusion

NASA Astrophysics Data System (ADS)

2006-05-01

Because plasma-boundary physics encompasses some of the most important unresolved issues for both the International Thermonuclear Experimental Reactor (ITER) project and future fusion power reactors, there is a strong interest in the fusion community for better understanding and characterization of plasma wall interactions. Chemical and physical sputtering cause the erosion of the limiters/divertor plates and vacuum vessel walls (made of C, Be and W, for example) and degrade fusion performance by diluting the fusion fuel and excessively cooling the core, while carbon redeposition could produce long-term in-vessel tritium retention, degrading the superior thermo-mechanical properties of the carbon materials. Mixed plasma-facing materials are proposed, requiring optimization for different power and particle flux characteristics. Knowledge of material properties as well as characteristics of the plasma material interaction are prerequisites for such optimizations. Computational power will soon reach hundreds of teraflops, so that theoretical and plasma science expertise can be matched with new experimental capabilities in order to mount a strong response to these challenges. To begin to address such questions, a Workshop on New Directions for Advanced Computer Simulations and Experiments in Fusion-Related Plasma Surface Interactions for Fusion (PSIF) was held at the Oak Ridge National Laboratory from 21 to 23 March, 2005. The purpose of the workshop was to bring together researchers in fusion related plasma wall interactions in order to address these topics and to identify the most needed and promising directions for study, to exchange opinions on the present depth of knowledge of surface properties for the main fusion-related materials, e.g., C, Be and W, especially for sputtering, reflection, and deuterium (tritium) retention properties. The goal was to suggest the most important next steps needed for such basic computational and experimental work to be facilitated by researchers in fusion, material, and physical sciences. Representatives from many fusion research laboratories attended, and 25 talks were given, the majority of them making up the content of these Workshop proceedings. The presentations of all talks and further information on the Workshop are available at http://www-cfadc.phy.ornl.gov/psif/home.html. The workshop talks dealt with identification of needs from the perspective of integrated fusion simulation and ITER design, recent developments and perspectives on computation of plasma-facing surface properties using the current and expected new generation of computation capability, and with the status of dedicated laboratory experiments which characterize the underlying processes of PSIF. The Workshop summary and conclusions are being published in Nuclear Fusion 45 (2005). We are indebted to Lynda Saddiq and Fay Ownby, secretaries in the Physics Division of ORNL, whose special efforts, devotion, and expertise made possible both the Workshop and these Proceedings. J T Hogan, P S Krstic and F W Meyer Physics Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831-6372, USA

Insights into the Functions of M-T Hook Structure in HIV Fusion Inhibitor Using Molecular Modeling.

PubMed

Tan, Jianjun; Yuan, Hongling; Li, Chunhua; Zhang, Xiaoyi; Wang, Cunxin

2016-04-01

HIV-1 membrane fusion plays an important role in the process that HIV-1 entries host cells. As a treatment strategy targeting HIV-1 entry process, fusion inhibitors have been proposed. Nevertheless, development of a short peptide possessing high anti-HIV potency is considered a daunting challenge. He et al. found that two residues, Met626 and Thr627, located the upstream of the C-terminal heptad repeat of the gp41, formed a unique hook-like structure (M-T hook) that can dramatically improve the binding stability and anti-HIV activity of the inhibitors. In this work, we explored the molecular mechanism why M-T hook structure could improve the anti-HIV activity of inhibitors. Firstly, molecular dynamic simulation was used to obtain information on the time evolution between gp41 and ligands. Secondly, based on the simulations, molecular mechanics Poisson-Boltzmann surface area (MM-PBSA) and molecular mechanics Generalized Born surface area (MM-GBSA) methods were used to calculate the binding free energies. The binding free energy of the ligand with M-T hook was considerably higher than the other without M-T. Further studies showed that the hydrophobic interactions made the dominant contribution to the binding free energy. The numbers of Hydrogen bonds between gp41 and the ligand with M-T hook structure were more than the other. These findings should provide insights into the inhibition mechanism of the short peptide fusion inhibitors and be useful for the rational design of novel fusion inhibitors in the future. Copyright © 2016 Elsevier Ltd. All rights reserved.

NIMROD resistive magnetohydrodynamic simulations of spheromak physics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hooper, E. B.; Cohen, B. I.; McLean, H. S.

The physics of spheromak plasmas is addressed by time-dependent, three-dimensional, resistive magnetohydrodynamic simulations with the NIMROD code [C. R. Sovinec et al., J. Comput. Phys. 195, 355 (2004)]. Included in some detail are the formation of a spheromak driven electrostatically by a coaxial plasma gun with a flux-conserver geometry and power systems that accurately model the sustained spheromak physics experiment [R. D. Wood et al., Nucl. Fusion 45, 1582 (2005)]. The controlled decay of the spheromak plasma over several milliseconds is also modeled as the programmable current and voltage relax, resulting in simulations of entire experimental pulses. Reconnection phenomena andmore » the effects of current profile evolution on the growth of symmetry-breaking toroidal modes are diagnosed; these in turn affect the quality of magnetic surfaces and the energy confinement. The sensitivity of the simulation results addresses variations in both physical and numerical parameters, including spatial resolution. There are significant points of agreement between the simulations and the observed experimental behavior, e.g., in the evolution of the magnetics and the sensitivity of the energy confinement to the presence of symmetry-breaking magnetic fluctuations.« less

NIMROD Resistive Magnetohydrodynamic Simulations of Spheromak Physics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hooper, E B; Cohen, B I; McLean, H S

The physics of spheromak plasmas is addressed by time-dependent, three-dimensional, resistive magneto-hydrodynamic simulations with the NIMROD code. Included in some detail are the formation of a spheromak driven electrostatically by a coaxial plasma gun with a flux-conserver geometry and power systems that accurately model the Sustained Spheromak Physics Experiment (SSPX) (R. D. Wood, et al., Nucl. Fusion 45, 1582 (2005)). The controlled decay of the spheromak plasma over several milliseconds is also modeled as the programmable current and voltage relax, resulting in simulations of entire experimental pulses. Reconnection phenomena and the effects of current profile evolution on the growth ofmore » symmetry-breaking toroidal modes are diagnosed; these in turn affect the quality of magnetic surfaces and the energy confinement. The sensitivity of the simulation results address variations in both physical and numerical parameters, including spatial resolution. There are significant points of agreement between the simulations and the observed experimental behavior, e.g., in the evolution of the magnetics and the sensitivity of the energy confinement to the presence of symmetry-breaking magnetic fluctuations.« less

Using Geostatistical Data Fusion Techniques and MODIS Data to Upscale Simulated Wheat Yield

NASA Astrophysics Data System (ADS)

Castrignano, A.; Buttafuoco, G.; Matese, A.; Toscano, P.

2014-12-01

Population growth increases food request. Assessing food demand and predicting the actual supply for a given location are critical components of strategic food security planning at regional scale. Crop yield can be simulated using crop models because is site-specific and determined by weather, management, length of growing season and soil properties. Crop models require reliable location-specific data that are not generally available. Obtaining these data at a large number of locations is time-consuming, costly and sometimes simply not feasible. An upscaling method to extend coverage of sparse estimates of crop yield to an appropriate extrapolation domain is required. This work is aimed to investigate the applicability of a geostatistical data fusion approach for merging remote sensing data with the predictions of a simulation model of wheat growth and production using ground-based data. The study area is Capitanata plain (4000 km2) located in Apulia Region, mostly cropped with durum wheat. The MODIS EVI/NDVI data products for Capitanata plain were downloaded from the Land Processes Distributed Active Archive Center (LPDAAC) remote for the whole crop cycle of durum wheat. Phenological development, biomass growth and grain quantity of durum wheat were simulated by the Delphi system, based on a crop simulation model linked to a database including soil properties, agronomical and meteorological data. Multicollocated cokriging was used to integrate secondary exhaustive information (multi-spectral MODIS data) with primary variable (sparsely distributed biomass/yield model predictions of durum wheat). The model estimates looked strongly spatially correlated with the radiance data (red and NIR bands) and the fusion data approach proved to be quite suitable and flexible to integrate data of different type and support.

Direct-drive DT implosions with Knudsen number variations

DOE PAGES

Kim, Yong Ho; Herrmann, Hans W.; Hoffman, Nelson M.; ...

2016-05-26

Direct-drive implosions of DT-filled plastic-shells have been conducted at the Omega laser facility, measuring nuclear yields while varying Knudsen numbers (i.e., the ratio of mean free path of fusing ions to the length of fuel region) by adjusting both shell thickness (e.g., 7.5, 15, 20, 30 μm) and fill pressure (e.g., 2, 5, 15 atm). In addition, the fusion reactivity reduction model showed a stronger effect on yield as the Knudsen number increases (or the shell thickness decreases). The Reduced-Ion-Kinetic (RIK) simulation which includes both fusion reactivity reduction and mix model was necessary to provide a better match between themore » observed neutron yields and those simulated.« less

Use of /sup 3/He/sup + +/ ICRF minority heating to simulate alpha particle heating

DOEpatents

Post, D.E. Jr.; Hwang, D.Q.; Hovey, J.

1983-11-16

It is an object of the present invention to provide a better understanding of alpha particle behavior in a magnetically confined, energetic plasma. Another object of the present invention is to provide an improved means and method for studying and measuring the energy distribution of heated alpha particles in a confined plasma. Yet another object of the present invention is to permit detailed analysis of energetic alpha particle behavior in a magnetically confined plasma for use in near term fusion reactor experiments. A still further object of the present invention is to simulate energetic alpha particle behavior in a deuterium-tritium plasma confined in a fusion reactor without producing the neutron activation associated with the thus produced alpha particles.

Influence of the parallel nonlinearity on zonal flows and heat transport in global gyrokinetic particle-in-cell simulations

NASA Astrophysics Data System (ADS)

Jolliet, S.; McMillan, B. F.; Vernay, T.; Villard, L.; Hatzky, R.; Bottino, A.; Angelino, P.

2009-07-01

In this paper, the influence of the parallel nonlinearity on zonal flows and heat transport in global particle-in-cell ion-temperature-gradient simulations is studied. Although this term is in theory orders of magnitude smaller than the others, several authors [L. Villard, P. Angelino, A. Bottino et al., Plasma Phys. Contr. Fusion 46, B51 (2004); L. Villard, S. J. Allfrey, A. Bottino et al., Nucl. Fusion 44, 172 (2004); J. C. Kniep, J. N. G. Leboeuf, and V. C. Decyck, Comput. Phys. Commun. 164, 98 (2004); J. Candy, R. E. Waltz, S. E. Parker et al., Phys. Plasmas 13, 074501 (2006)] found different results on its role. The study is performed using the global gyrokinetic particle-in-cell codes TORB (theta-pinch) [R. Hatzky, T. M. Tran, A. Könies et al., Phys. Plasmas 9, 898 (2002)] and ORB5 (tokamak geometry) [S. Jolliet, A. Bottino, P. Angelino et al., Comput. Phys. Commun. 177, 409 (2007)]. In particular, it is demonstrated that the parallel nonlinearity, while important for energy conservation, affects the zonal electric field only if the simulation is noise dominated. When a proper convergence is reached, the influence of parallel nonlinearity on the zonal electric field, if any, is shown to be small for both the cases of decaying and driven turbulence.

First-principles investigations on ionization and thermal conductivity of polystyrene for inertial confinement fusion applications

DOE PAGES

Hu, S. X.; Collins, Lee A.; Goncharov, V. N.; ...

2016-04-14

Using quantum molecular-dynamics (QMD) methods based on the density functional theory, we have performed first-principles investigations on the ionization and thermal conductivity of polystyrene (CH) over a wide range of plasma conditions (ρ = 0.5 to 100 g/cm 3 and T = 15,625 to 500,000 K). The ionization data from orbital-free molecular-dynamics calculations have been fitted with a “Saha-type” model as a function of the CH plasma density and temperature, which exhibits the correct behaviors of continuum lowering and pressure ionization. The thermal conductivities (κ QMD) of CH, derived directly from the Kohn–Sham molecular-dynamics calculations, are then analytically fitted withmore » a generalized Coulomb logarithm [(lnΛ) QMD] over a wide range of plasma conditions. When compared with the traditional ionization and thermal conductivity models used in radiation–hydrodynamics codes for inertial confinement fusion simulations, the QMD results show a large difference in the low-temperature regime in which strong coupling and electron degeneracy play an essential role in determining plasma properties. Furthermore, hydrodynamic simulations of cryogenic deuterium–tritium targets with CH ablators on OMEGA and the National Ignition Facility using the QMD-derived ionization and thermal conductivity of CH have predicted –20% variation in target performance in terms of hot-spot pressure and neutron yield (gain) with respect to traditional model simulations.« less

Two-dimensional implosion simulations with a kinetic particle code [2D implosion simulations with a kinetic particle code

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sagert, Irina; Even, Wesley Paul; Strother, Terrance Timothy

Here, we perform two-dimensional implosion simulations using a Monte Carlo kinetic particle code. The application of a kinetic transport code is motivated, in part, by the occurrence of nonequilibrium effects in inertial confinement fusion capsule implosions, which cannot be fully captured by hydrodynamic simulations. Kinetic methods, on the other hand, are able to describe both continuum and rarefied flows. We perform simple two-dimensional disk implosion simulations using one-particle species and compare the results to simulations with the hydrodynamics code rage. The impact of the particle mean free path on the implosion is also explored. In a second study, we focusmore » on the formation of fluid instabilities from induced perturbations. We find good agreement with hydrodynamic studies regarding the location of the shock and the implosion dynamics. Differences are found in the evolution of fluid instabilities, originating from the higher resolution of rage and statistical noise in the kinetic studies.« less

Two-dimensional implosion simulations with a kinetic particle code [2D implosion simulations with a kinetic particle code

DOE PAGES

Sagert, Irina; Even, Wesley Paul; Strother, Terrance Timothy

2017-05-17

Here, we perform two-dimensional implosion simulations using a Monte Carlo kinetic particle code. The application of a kinetic transport code is motivated, in part, by the occurrence of nonequilibrium effects in inertial confinement fusion capsule implosions, which cannot be fully captured by hydrodynamic simulations. Kinetic methods, on the other hand, are able to describe both continuum and rarefied flows. We perform simple two-dimensional disk implosion simulations using one-particle species and compare the results to simulations with the hydrodynamics code rage. The impact of the particle mean free path on the implosion is also explored. In a second study, we focusmore » on the formation of fluid instabilities from induced perturbations. We find good agreement with hydrodynamic studies regarding the location of the shock and the implosion dynamics. Differences are found in the evolution of fluid instabilities, originating from the higher resolution of rage and statistical noise in the kinetic studies.« less

Effect of Lumbar Lordosis on the Adjacent Segment in Transforaminal Lumbar Interbody Fusion: A Finite Element Analysis.

PubMed

Zhao, Xin; Du, Lin; Xie, Youzhuan; Zhao, Jie

2018-06-01

We used a finite element (FE) analysis to investigate the biomechanical changes caused by transforaminal lumbar interbody fusion (TLIF) at the L4-L5 level by lumbar lordosis (LL) degree. A lumbar FE model (L1-S5) was constructed based on computed tomography scans of a 30-year-old healthy male volunteer (pelvic incidence,= 50°; LL, 52°). We investigated the influence of LL on the biomechanical behavior of the lumbar spine after TLIF in L4-L5 fusion models with 57°, 52°, 47°, and 40° LL. The LL was defined as the angle between the superior end plate of L1 and the superior end plate of S1. A 150-N vertical axial preload was imposed on the superior surface of L3. A 10-N/m moment was simultaneously applied on the L3 superior surface along the radial direction to simulate the 4 basic physiologic motions of flexion, extension, lateral bending, and torsion in the numeric simulations. The range of motion (ROM) and intradiscal pressure (IDP) of L3-L4 were evaluated and compared in the simulated cases. In all motion patterns, the ROM and IDP were both increased after TLIF. In addition, the decrease in lordosis generally increased the ROM and IDP in all motion patterns. This FE analysis indicated that decreased spinal lordosis may evoke overstress of the adjacent segment and increase the risk of the pathologic development of adjacent segment degeneration; thus, adjacent segment degeneration should be considered when planning a spinal fusion procedure. Copyright © 2018. Published by Elsevier Inc.

Three-dimensional modeling of the neutron spectrum to infer plasma conditions in cryogenic inertial confinement fusion implosions

NASA Astrophysics Data System (ADS)

Weilacher, F.; Radha, P. B.; Forrest, C.

2018-04-01

Neutron-based diagnostics are typically used to infer compressed core conditions such as areal density and ion temperature in deuterium-tritium (D-T) inertial confinement fusion (ICF) implosions. Asymmetries in the observed neutron-related quantities are important to understanding failure modes in these implosions. Neutrons from fusion reactions and their subsequent interactions including elastic scattering and neutron-induced deuteron breakup reactions are tracked to create spectra. It is shown that background subtraction is important for inferring areal density from backscattered neutrons and is less important for the forward-scattered neutrons. A three-dimensional hydrodynamic simulation of a cryogenic implosion on the OMEGA Laser System [Boehly et al., Opt. Commun. 133, 495 (1997)] using the hydrodynamic code HYDRA [Marinak et al., Phys. Plasmas 8, 2275 (2001)] is post-processed using the tracking code IRIS3D. It is shown that different parts of the neutron spectrum from the view can be mapped into different regions of the implosion, enabling an inference of an areal-density map. It is also shown that the average areal-density and an areal-density map of the compressed target can be reconstructed with a finite number of detectors placed around the target chamber. Ion temperatures are inferred from the width of the D-D and D-T fusion neutron spectra. Backgrounds can significantly alter the inferred ion temperatures from the D-D reaction, whereas they insignificantly influence the inferred D-T ion temperatures for the areal densities typical of OMEGA implosions. Asymmetries resulting in fluid flow in the core are shown to influence the absolute inferred ion temperatures from both reactions, although relative inferred values continue to reflect the underlying asymmetry pattern. The work presented here is part of the wide range of the first set of studies performed with IRIS3D. This code will continue to be used for post-processing detailed hydrodynamic simulations and interpreting observed neutron spectra in ICF implosions.

The ePLAS Code for Ignition Studies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mason, Rodney J

2012-09-20

Inertial Confinement Fusion (ICF) presents unique opportunities for the extraction of clean energy from Fusion. Intense lasers and particle beams can create and interact with such plasmas, potentially yielding sufficient energy to satisfy all our national needs. However, few models are available to help aid the scientific community in the study and optimization of such interactions. This project enhanced and disseminated the computer code ePLAS for the early understanding and control of Ignition in ICF. ePLAS is a unique simulation code that tracks the transport of laser light to a target, the absorption of that light resulting in the generationmore » and transport of hot electrons, and the heating and flow dynamics of the background plasma. It uses an implicit electromagnetic field-solving method to greatly reduce computing demands, so that useful target interaction studies can often be completed in 15 minutes on a portable 2.1 GHz PC. The code permits the rapid scoping of calculations for the optimization of laser target interactions aimed at fusion. Recent efforts have initiated the use of analytic equations of state (EOS), K-alpha image rendering graphics, allocatable memory for source-free usage, and adaption to the latest Mac and Linux Operating Systems. The speed and utility of ePLAS are unequaled in the ICF simulation community. This project evaluated the effects of its new EOSs on target heating, compared fluid and particle models for the ions, initiated the simultaneous use of both ion models in the code, and studied long time scale 500 ps hot electron deposition for shock ignition. ePLAS has been granted EAR99 export control status, permitting export without a license to most foreign countries. Beta-test versions of ePLAS have been granted to several Universities and Commercial users. The net Project was aimed at achieving early success in the laboratory ignition of thermonuclear targets and the mastery of controlled fusion power for the nation.« less

A review on ab initio studies of static, transport, and optical properties of polystyrene under extreme conditions for inertial confinement fusion applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Collins, L. A.; Boehly, T. R.; Ding, Y. H.

Polystyrene (CH), commonly known as “plastic,” has been one of the widely used ablator materials for capsule designs in inertial confinement fusion (ICF). Knowing its precise properties under high-energy-density conditions is crucial to understanding and designing ICF implosions through radiation–hydrodynamic simulations. For this purpose, systematic ab initio studies on the static, transport, and optical properties of CH, in a wide range of density and temperature conditions (ρ= 0.1 to 100 g/cm 3 and T = 10 3 to 4 × 10 6K), have been conducted using quantum molecular dynamics (QMD) simulations based on the density functional theory. We have builtmore » several wide-ranging, self-consistent material-properties tables for CH, such as the first-principles equation of state (FPEOS), the QMD-based thermal conductivity (Κ QMD) and ionization, and the first-principles opacity table (FPOT). This paper is devoted to providing a review on (1) what results were obtained from these systematic ab initio studies; (2) how these self-consistent results were compared with both traditional plasma-physics models and available experiments; and (3) how these first-principles–based properties of polystyrene affect the predictions of ICF target performance, through both 1-D and 2-D radiation–hydrodynamic simulations. In the warm dense regime, our ab initio results, which can significantly differ from predictions of traditional plasma-physics models, compared favorably with experiments. When incorporated into hydrocodes for ICF simulations, these first-principles material properties of CH have produced significant differences over traditional models in predicting 1-D/2-D target performance of ICF implosions on OMEGA and direct-drive–ignition designs for the National Ignition Facility. Lastly, we will discuss the implications of these studies on the current small-margin ICF target designs using a CH ablator.« less

A review on ab initio studies of static, transport, and optical properties of polystyrene under extreme conditions for inertial confinement fusion applications

DOE PAGES

Collins, L. A.; Boehly, T. R.; Ding, Y. H.; ...

2018-03-23

Polystyrene (CH), commonly known as “plastic,” has been one of the widely used ablator materials for capsule designs in inertial confinement fusion (ICF). Knowing its precise properties under high-energy-density conditions is crucial to understanding and designing ICF implosions through radiation–hydrodynamic simulations. For this purpose, systematic ab initio studies on the static, transport, and optical properties of CH, in a wide range of density and temperature conditions (ρ= 0.1 to 100 g/cm 3 and T = 10 3 to 4 × 10 6K), have been conducted using quantum molecular dynamics (QMD) simulations based on the density functional theory. We have builtmore » several wide-ranging, self-consistent material-properties tables for CH, such as the first-principles equation of state (FPEOS), the QMD-based thermal conductivity (Κ QMD) and ionization, and the first-principles opacity table (FPOT). This paper is devoted to providing a review on (1) what results were obtained from these systematic ab initio studies; (2) how these self-consistent results were compared with both traditional plasma-physics models and available experiments; and (3) how these first-principles–based properties of polystyrene affect the predictions of ICF target performance, through both 1-D and 2-D radiation–hydrodynamic simulations. In the warm dense regime, our ab initio results, which can significantly differ from predictions of traditional plasma-physics models, compared favorably with experiments. When incorporated into hydrocodes for ICF simulations, these first-principles material properties of CH have produced significant differences over traditional models in predicting 1-D/2-D target performance of ICF implosions on OMEGA and direct-drive–ignition designs for the National Ignition Facility. Lastly, we will discuss the implications of these studies on the current small-margin ICF target designs using a CH ablator.« less

Deuterium sputtering of Li and Li-O films

NASA Astrophysics Data System (ADS)

Nelson, Andrew; Buzi, Luxherta; Kaita, Robert; Koel, Bruce

2017-10-01

Lithium wall coatings have been shown to enhance the operational plasma performance of many fusion devices, including NSTX and other tokamaks, by reducing the global wall recycling coefficient. However, pure lithium surfaces are extremely difficult to maintain in experimental fusion devices due to both inevitable oxidation and codeposition from sputtering of hot plasma facing components. Sputtering of thin lithium and lithium oxide films on a molybdenum target by energetic deuterium ion bombardment was studied in laboratory experiments conducted in a surface science apparatus. A Colutron ion source was used to produce a monoenergetic, mass-selected ion beam. Measurements were made under ultrahigh vacuum conditions as a function of surface temperature (90-520 K) using x-ray photoelectron spectroscopy (XPS), Auger electron spectroscopy (AES) and temperature programmed desorption (TPD). Results are compared with computer simulations conducted on a temperature-dependent data-calibrated (TRIM) model.

Hole Boring in a DT Pellet and Fast-Ion Ignition with Ultraintense Laser Pulses

DOE Office of Scientific and Technical Information (OSTI.GOV)

Naumova, N.; Mourou, G.; Schlegel, T.

Recently achieved high intensities of short laser pulses open new prospects in their application to hole boring in inhomogeneous overdense plasmas and for ignition in precompressed DT fusion targets. A simple analytical model and numerical simulations demonstrate that pulses with intensities exceeding 10{sup 22} W/cm{sup 2} may penetrate deeply into the plasma as a result of efficient ponderomotive acceleration of ions in the forward direction. The penetration depth as big as hundreds of microns depends on the laser fluence, which has to exceed a few tens of GJ/cm{sup 2}. The fast ions, accelerated at the bottom of the channel withmore » an efficiency of more than 20%, show a high directionality and may heat the precompressed target core to fusion conditions.« less

Analysis of the sEMG/force relationship using HD-sEMG technique and data fusion: A simulation study.

PubMed

Al Harrach, Mariam; Carriou, Vincent; Boudaoud, Sofiane; Laforet, Jeremy; Marin, Frederic

2017-04-01

The relationship between the surface Electromyogram (sEMG) signal and the force of an individual muscle is still ambiguous due to the complexity of experimental evaluation. However, understanding this relationship should be useful for the assessment of neuromuscular system in healthy and pathological contexts. In this study, we present a global investigation of the factors governing the shape of this relationship. Accordingly, we conducted a focused sensitivity analysis of the sEMG/force relationship form with respect to neural, functional and physiological parameters variation. For this purpose, we used a fast generation cylindrical model for the simulation of an 8×8 High Density-sEMG (HD-sEMG) grid and a twitch based force model for the muscle force generation. The HD-sEMG signals as well as the corresponding force signals were simulated in isometric non-fatiguing conditions and were based on the Biceps Brachii (BB) muscle properties. A total of 10 isometric constant contractions of 5s were simulated for each configuration of parameters. The Root Mean Squared (RMS) value was computed in order to quantify the sEMG amplitude. Then, an image segmentation method was used for data fusion of the 8×8 RMS maps. In addition, a comparative study between recent modeling propositions and the model proposed in this study is presented. The evaluation was made by computing the Normalized Root Mean Squared Error (NRMSE) of their fitting to the simulated relationship functions. Our results indicated that the relationship between the RMS (mV) and muscle force (N) can be modeled using a 3rd degree polynomial equation. Moreover, it appears that the obtained coefficients are patient-specific and dependent on physiological, anatomical and neural parameters. Copyright © 2017 Elsevier Ltd. All rights reserved.

GNSS-ISR data fusion: General framework with application to the high-latitude ionosphere

NASA Astrophysics Data System (ADS)

Semeter, Joshua; Hirsch, Michael; Lind, Frank; Coster, Anthea; Erickson, Philip; Pankratius, Victor

2016-03-01

A mathematical framework is presented for the fusion of electron density measured by incoherent scatter radar (ISR) and total electron content (TEC) measured using global navigation satellite systems (GNSS). Both measurements are treated as projections of an unknown density field (for GNSS-TEC the projection is tomographic; for ISR the projection is a weighted average over a local spatial region) and discrete inverse theory is applied to obtain a higher fidelity representation of the field than could be obtained from either modality individually. The specific implementation explored herein uses the interpolated ISR density field as initial guess to the combined inverse problem, which is subsequently solved using maximum entropy regularization. Simulations involving a dense meridional network of GNSS receivers near the Poker Flat ISR demonstrate the potential of this approach to resolve sub-beam structure in ISR measurements. Several future directions are outlined, including (1) data fusion using lower level (lag product) ISR data, (2) consideration of the different temporal sampling rates, (3) application of physics-based regularization, (4) consideration of nonoptimal observing geometries, and (5) use of an ISR simulation framework for optimal experiment design.

Pulsed-power-driven cylindrical liner implosions of laser preheated fuel magnetized with an axial field

DOE Office of Scientific and Technical Information (OSTI.GOV)

Slutz, S. A.; Herrmann, M. C.; Vesey, R. A.

2010-05-15

The radial convergence required to reach fusion conditions is considerably higher for cylindrical than for spherical implosions since the volume is proportional to r{sup 2} versus r{sup 3}, respectively. Fuel magnetization and preheat significantly lowers the required radial convergence enabling cylindrical implosions to become an attractive path toward generating fusion conditions. Numerical simulations are presented indicating that significant fusion yields may be obtained by pulsed-power-driven implosions of cylindrical metal liners onto magnetized (>10 T) and preheated (100-500 eV) deuterium-tritium (DT) fuel. Yields exceeding 100 kJ could be possible on Z at 25 MA, while yields exceeding 50 MJ could bemore » possible with a more advanced pulsed power machine delivering 60 MA. These implosions occur on a much shorter time scale than previously proposed implosions, about 100 ns as compared to about 10 mus for magnetic target fusion (MTF) [I. R. Lindemuth and R. C. Kirkpatrick, Nucl. Fusion 23, 263 (1983)]. Consequently the optimal initial fuel density (1-5 mg/cc) is considerably higher than for MTF (approx1 mug/cc). Thus the final fuel density is high enough to axially trap most of the alpha-particles for cylinders of approximately 1 cm in length with a purely axial magnetic field, i.e., no closed field configuration is required for ignition. According to the simulations, an initial axial magnetic field is partially frozen into the highly conducting preheated fuel and is compressed to more than 100 MG. This final field is strong enough to inhibit both electron thermal conduction and the escape of alpha-particles in the radial direction. Analytical and numerical calculations indicate that the DT can be heated to 200-500 eV with 5-10 kJ of green laser light, which could be provided by the Z-Beamlet laser. The magneto-Rayleigh-Taylor (MRT) instability poses the greatest threat to this approach to fusion. Two-dimensional Lasnex simulations indicate that the liner walls must have a substantial initial thickness (10-20% of the radius) so that they maintain integrity throughout the implosion. The Z and Z-Beamlet experiments are now being planned to test the various components of this concept, e.g., the laser heating of the fuel and the robustness of liner implosions to the MRT instability.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Kezhao; Ni, Longchang; Lei, Zhenglong, E-ma

The tensile deformation behavior of laser welded Ti{sub 2}AlNb joints was investigated using in situ analysis methods. The fracture mode of the single-B2-phase fusion zone was quasi-cleavage at room temperature and intergranular at 650 °C, while that of base metal was microvoid coalescence at both room temperature and 650 °C. Tensile deformation at room temperature was observed using in situ SEM tensile testing. In base metal, microcracks nucleated and propagated mainly within the O phase or along O/B2 phase boundaries. While both the cross- and multi-slips were found in the single-B2-phase fusion zone, a confocal laser scanning microscopy was usedmore » to observe the crack initiation and propagation process in situ at 650 °C. Cracks mainly formed along the B2/O phase boundaries in base metal, along the fragile grain boundaries of B2 phase in the fusion zone. The thermal simulation experiment and following TEM analysis indicated that the precipitation of continuous O-phase films along the B2 grain boundaries resulted in the high temperature brittleness of laser welded Ti{sub 2}AlNb joints. - Highlights: •Cracks formed within O phase or along B2/O boundaries in the base metal. •Cross- and multi-slips relieved stress in the fusion zone at room temperature. •Cracks mainly formed along the B2/O boundaries at 650 °C. •In the fusion zone, intergranular cracks were in situ observed at 650 °C. •O-phase films along B2 grain boundaries caused the high temperature brittleness.« less

Self-similar structure and experimental signatures of suprathermal ion distribution in inertial confinement fusion implosions

DOE PAGES

Kagan, Grigory; Svyatskiy, D.; Rinderknecht, H. G.; ...

2015-09-03

The distribution function of suprathermal ions is found to be self-similar under conditions relevant to inertial confinement fusion hot spots. By utilizing this feature, interference between the hydrodynamic instabilities and kinetic effects is for the first time assessed quantitatively to find that the instabilities substantially aggravate the fusion reactivity reduction. Thus, the ion tail depletion is also shown to lower the experimentally inferred ion temperature, a novel kinetic effect that may explain the discrepancy between the exploding pusher experiments and rad-hydro simulations and contribute to the observation that temperature inferred from DD reaction products is lower than from DT atmore » the National Ignition Facility.« less

Self-Similar Structure and Experimental Signatures of Suprathermal Ion Distribution in Inertial Confinement Fusion Implosions

NASA Astrophysics Data System (ADS)

Kagan, Grigory; Svyatskiy, D.; Rinderknecht, H. G.; Rosenberg, M. J.; Zylstra, A. B.; Huang, C.-K.; McDevitt, C. J.

2015-09-01

The distribution function of suprathermal ions is found to be self-similar under conditions relevant to inertial confinement fusion hot spots. By utilizing this feature, interference between the hydrodynamic instabilities and kinetic effects is for the first time assessed quantitatively to find that the instabilities substantially aggravate the fusion reactivity reduction. The ion tail depletion is also shown to lower the experimentally inferred ion temperature, a novel kinetic effect that may explain the discrepancy between the exploding pusher experiments and rad-hydro simulations and contribute to the observation that temperature inferred from DD reaction products is lower than from DT at the National Ignition Facility.

Parallel Molecular Distributed Detection With Brownian Motion.

PubMed

Rogers, Uri; Koh, Min-Sung

2016-12-01

This paper explores the in vivo distributed detection of an undesired biological agent's (BAs) biomarkers by a group of biological sized nanomachines in an aqueous medium under drift. The term distributed, indicates that the system information relative to the BAs presence is dispersed across the collection of nanomachines, where each nanomachine possesses limited communication, computation, and movement capabilities. Using Brownian motion with drift, a probabilistic detection and optimal data fusion framework, coined molecular distributed detection, will be introduced that combines theory from both molecular communication and distributed detection. Using the optimal data fusion framework as a guide, simulation indicates that a sub-optimal fusion method exists, allowing for a significant reduction in implementation complexity while retaining BA detection accuracy.

Simulations of inertial confinement fusion driven by a novel synchrotron-radiation-based x-ray igniter

NASA Astrophysics Data System (ADS)

Shlyaptsev, Vyacheslav N.; Tatchyn, Roman O.

2004-01-01

The advantages and challenges of using a powerful x-ray source for the fast ignition of compressed Inertial Confinement Fusion (ICF) targets have been considered. The requirements for such a source together with the optics to focus the x-rays onto compressed DT cores lead to a conceptual design based on Energy Recovery Linacs (ERLs) and long wigglers to produce x-ray pulses with the appropriate phase space properties. A comparative assessment of the parameters of the igniter system indicates that the technologies for building it, although expensive, are physically achievable. Our x-ray fast ignition (XFI) scheme requires substantially smaller energy for the initiation of nuclear fusion reactions than other methods.

Three-Dimensional Modeling of Low-Mode Asymmetries in OMEGA Cryogenic Implosions

NASA Astrophysics Data System (ADS)

Anderson, K. S.; McKenty, P. W.; Shvydky, A.; Collins, T. J. B.; Forrest, C. J.; Knauer, J. P.; Marozas, J. A.; Marshall, F. J.; Radha, P. B.; Sefkow, A. B.; Marinak, M. M.

2017-10-01

In direct-drive inertial confinement fusion implosions, long-wavelength asymmetries resulting from target offset, laser power imbalance, beam mispointing, etc. can be highly detrimental to target performance. Characterizing the effects of these asymmetry sources requires 3-D simulations performed in full-sphere geometry to accurately capture the evolution of shell perturbations and hot-spot flow. This paper will present 3-D HYDRA simulations characterizing the impact of these perturbation sources on yield and shell modulation. Various simulated observables are generated, and trends are analyzed and compared with experimental data. This material is based on work supported by the Department of Energy National Nuclear Security Administration under Award Numbers DE-NA0001944 and performed under the auspices of the LLNL under Contract No. DE-AC52-07NA27344.

Effects of alpha stopping power modelling on the ignition threshold in a directly-driven inertial confinement fusion capsule

NASA Astrophysics Data System (ADS)

Temporal, Mauro; Canaud, Benoit; Cayzac, Witold; Ramis, Rafael; Singleton, Robert L.

2017-05-01

The alpha-particle energy deposition mechanism modifies the ignition conditions of the thermonuclear Deuterium-Tritium fusion reactions, and constitutes a key issue in achieving high gain in Inertial Confinement Fusion implosions. One-dimensional hydrodynamic calculations have been performed with the code Multi-IFE [R. Ramis, J. Meyer-ter-Vehn, Comput. Phys. Commun. 203, 226 (2016)] to simulate the implosion of a capsule directly irradiated by a laser beam. The diffusion approximation for the alpha energy deposition has been used to optimize three laser profiles corresponding to different implosion velocities. A Monte-Carlo package has been included in Multi-IFE to calculate the alpha energy transport, and in this case the energy deposition uses both the LP [C.K. Li, R.D. Petrasso, Phys. Rev. Lett. 70, 3059 (1993)] and the BPS [L.S. Brown, D.L. Preston, R.L. Singleton Jr., Phys. Rep. 410, 237 (2005)] stopping power models. Homothetic transformations that maintain a constant implosion velocity have been used to map out the transition region between marginally-igniting and high-gain configurations. The results provided by the two models have been compared and it is found that - close to the ignition threshold - in order to produce the same fusion energy, the calculations performed with the BPS model require about 10% more invested energy with respect to the LP model.

Simulation and Analysis of Isotope Separation System for Fusion Fuel Recovery System

NASA Astrophysics Data System (ADS)

Senevirathna, Bathiya; Gentile, Charles

2011-10-01

This paper presents results of a simulation of the Fuel Recovery System (FRS) for the Laser Inertial Fusion Engine (LIFE) reactor. The LIFE reaction will produce exhaust gases that will need to be recycled in the FRS along with xenon, the chamber's intervention gas. Solids and liquids will first be removed and then vapor traps are used to remove large gas molecules such as lead. The gas will be reacted with lithium at high temperatures to extract the hydrogen isotopes, protium, deuterium, and tritium in hydride form. The hydrogen isotopes will be recovered using a lithium blanket processing system already in place and this product will be sent to the Isotope Separation System (ISS). The ISS will be modeled in software to analyze its effectiveness. Aspen HYSYS was chosen for this purpose for its widespread use industrial gas processing systems. Reactants and corresponding chemical reactions had to be initialized in the software. The ISS primarily consists of four cryogenic distillation columns and these were modeled in HYSYS based on design requirements. Fractional compositions of the distillate and liquid products were analyzed and used to optimize the overall system.

Efficient free energy calculations of quantum systems through computer simulations

NASA Astrophysics Data System (ADS)

Antonelli, Alex; Ramirez, Rafael; Herrero, Carlos; Hernandez, Eduardo

2009-03-01

In general, the classical limit is assumed in computer simulation calculations of free energy. This approximation, however, is not justifiable for a class of systems in which quantum contributions for the free energy cannot be neglected. The inclusion of quantum effects is important for the determination of reliable phase diagrams of these systems. In this work, we present a new methodology to compute the free energy of many-body quantum systems [1]. This methodology results from the combination of the path integral formulation of statistical mechanics and efficient non-equilibrium methods to estimate free energy, namely, the adiabatic switching and reversible scaling methods. A quantum Einstein crystal is used as a model to show the accuracy and reliability the methodology. This new method is applied to the calculation of solid-liquid coexistence properties of neon. Our findings indicate that quantum contributions to properties such as, melting point, latent heat of fusion, entropy of fusion, and slope of melting line can be up to 10% of the calculated values using the classical approximation. [1] R. M. Ramirez, C. P. Herrero, A. Antonelli, and E. R. Hernández, Journal of Chemical Physics 129, 064110 (2008)

Learning and diagnosing faults using neural networks

NASA Technical Reports Server (NTRS)

Whitehead, Bruce A.; Kiech, Earl L.; Ali, Moonis

1990-01-01

Neural networks have been employed for learning fault behavior from rocket engine simulator parameters and for diagnosing faults on the basis of the learned behavior. Two problems in applying neural networks to learning and diagnosing faults are (1) the complexity of the sensor data to fault mapping to be modeled by the neural network, which implies difficult and lengthy training procedures; and (2) the lack of sufficient training data to adequately represent the very large number of different types of faults which might occur. Methods are derived and tested in an architecture which addresses these two problems. First, the sensor data to fault mapping is decomposed into three simpler mappings which perform sensor data compression, hypothesis generation, and sensor fusion. Efficient training is performed for each mapping separately. Secondly, the neural network which performs sensor fusion is structured to detect new unknown faults for which training examples were not presented during training. These methods were tested on a task of fault diagnosis by employing rocket engine simulator data. Results indicate that the decomposed neural network architecture can be trained efficiently, can identify faults for which it has been trained, and can detect the occurrence of faults for which it has not been trained.

The Flocculating Cationic Polypetide from Moringa oleifera Seeds Damages Bacterial Cell Membranes by Causing Membrane Fusion.

PubMed

Shebek, Kevin; Schantz, Allen B; Sines, Ian; Lauser, Kathleen; Velegol, Stephanie; Kumar, Manish

2015-04-21

A cationic protein isolated from the seeds of the Moringa oleifera tree has been extensively studied for use in water treatment in developing countries and has been proposed for use in antimicrobial and therapeutic applications. However, the molecular basis for the antimicrobial action of this peptide, Moringa oleifera cationic protein (MOCP), has not been previously elucidated. We demonstrate here that a dominant mechanism of MOCP antimicrobial activity is membrane fusion. We used a combination of cryogenic electron microscopy (cryo-EM) and fluorescence assays to observe and study the kinetics of fusion of membranes in liposomes representing model microbial cells. We also conducted cryo-EM experiments on E. coli cells where MOCP was seen to fuse the inner and outer membranes. Coarse-grained molecular dynamics simulations of membrane vesicles with MOCP molecules were used to elucidate steps in peptide adsorption, stalk formation, and fusion between membranes.

General software design for multisensor data fusion

NASA Astrophysics Data System (ADS)

Zhang, Junliang; Zhao, Yuming

1999-03-01

In this paper a general method of software design for multisensor data fusion is discussed in detail, which adopts object-oriented technology under UNIX operation system. The software for multisensor data fusion is divided into six functional modules: data collection, database management, GIS, target display and alarming data simulation etc. Furthermore, the primary function, the components and some realization methods of each modular is given. The interfaces among these functional modular relations are discussed. The data exchange among each functional modular is performed by interprocess communication IPC, including message queue, semaphore and shared memory. Thus, each functional modular is executed independently, which reduces the dependence among functional modules and helps software programing and testing. This software for multisensor data fusion is designed as hierarchical structure by the inheritance character of classes. Each functional modular is abstracted and encapsulated through class structure, which avoids software redundancy and enhances readability.

Fission and fusion scenarios for magnetic microswimmer clusters

DOE Office of Scientific and Technical Information (OSTI.GOV)

Guzmán-Lastra, Francisca; Kaiser, Andreas; Löwen, Hartmut

Fission and fusion processes of particle clusters occur in many areas of physics and chemistry from subnuclear to astronomic length scales. Here we study fission and fusion of magnetic microswimmer clusters as governed by their hydrodynamic and dipolar interactions. Rich scenarios are found that depend crucially on whether the swimmer is a pusher or a puller. In particular a linear magnetic chain of pullers is stable while a pusher chain shows a cascade of fission (or disassembly) processes as the self-propulsion velocity is increased. Contrarily, magnetic ring clusters show fission for any type of swimmer. Moreover, we find a plethoramore » of possible fusion (or assembly) scenarios if a single swimmer collides with a ringlike cluster and two rings spontaneously collide. Lastly, our predictions are obtained by computer simulations and verifiable in experiments on active colloidal Janus particles and magnetotactic bacteria.« less

Overview of Heavy Ion Fusion Accelerator Research in the U. S.

NASA Astrophysics Data System (ADS)

Friedman, Alex

2002-12-01

This article provides an overview of current U.S. research on accelerators for Heavy Ion Fusion, that is, inertial fusion driven by intense beams of heavy ions with the goal of energy production. The concept, beam requirements, approach, and major issues are introduced. An overview of a number of new experiments is presented. These include: the High Current Experiment now underway at Lawrence Berkeley National Laboratory; studies of advanced injectors (and in particular an approach based on the merging of multiple beamlets), being investigated experimentally at Lawrence Livermore National Laboratory); the Neutralized (chamber) Transport Experiment being assembled at Lawrence Berkeley National Laboratory; and smaller experiments at the University of Maryland and at Princeton Plasma Physics Laboratory. The comprehensive program of beam simulations and theory is outlined. Finally, prospects and plans for further development of this promising approach to fusion energy are discussed.

Estimation and Fusion for Tracking Over Long-Haul Links Using Artificial Neural Networks

DOE PAGES

Liu, Qiang; Brigham, Katharine; Rao, Nageswara S. V.

2017-02-01

In a long-haul sensor network, sensors are remotely deployed over a large geographical area to perform certain tasks, such as tracking and/or monitoring of one or more dynamic targets. A remote fusion center fuses the information provided by these sensors so that a final estimate of certain target characteristics – such as the position – is expected to possess much improved quality. In this paper, we pursue learning-based approaches for estimation and fusion of target states in longhaul sensor networks. In particular, we consider learning based on various implementations of artificial neural networks (ANNs). Finally, the joint effect of (i)more » imperfect communication condition, namely, link-level loss and delay, and (ii) computation constraints, in the form of low-quality sensor estimates, on ANN-based estimation and fusion, is investigated by means of analytical and simulation studies.« less

Progress in magnet design activities for the material plasma exposure experiment

DOE PAGES

Duckworth, Robert; Lumsdaine, Arnold; Rapp, Juergen; ...

2017-07-01

One of the critical challenges for the development of next generation fusion facilities, such as a Fusion Nuclear Science Facility (FNSF) or DEMO, is the understanding of plasma material interactions (PMI). Making progress in PMI research will require integrated facilities that can provide the types of conditions that will be seen in the first wall and divertor regions of future fusion facilities. In order to meet this need, a new linear plasma facility, the Materials Plasma Exposure Experiment (MPEX), is proposed. In order to generate high ion fluence to simulate fusion divertor conditions, a steady-state plasma will be generated andmore » confined with superconducting magnets. Finally, the on-axis fields will range from 1 to 2.5 T in order to meet the requirements of the various plasma source and heating systems. Details on the pre-conceptual design of the magnets and cryogenic system are presented.« less

Fission and fusion scenarios for magnetic microswimmer clusters

DOE PAGES

Guzmán-Lastra, Francisca; Kaiser, Andreas; Löwen, Hartmut

2016-11-22

Fission and fusion processes of particle clusters occur in many areas of physics and chemistry from subnuclear to astronomic length scales. Here we study fission and fusion of magnetic microswimmer clusters as governed by their hydrodynamic and dipolar interactions. Rich scenarios are found that depend crucially on whether the swimmer is a pusher or a puller. In particular a linear magnetic chain of pullers is stable while a pusher chain shows a cascade of fission (or disassembly) processes as the self-propulsion velocity is increased. Contrarily, magnetic ring clusters show fission for any type of swimmer. Moreover, we find a plethoramore » of possible fusion (or assembly) scenarios if a single swimmer collides with a ringlike cluster and two rings spontaneously collide. Lastly, our predictions are obtained by computer simulations and verifiable in experiments on active colloidal Janus particles and magnetotactic bacteria.« less

Estimation and Fusion for Tracking Over Long-Haul Links Using Artificial Neural Networks

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, Qiang; Brigham, Katharine; Rao, Nageswara S. V.

In a long-haul sensor network, sensors are remotely deployed over a large geographical area to perform certain tasks, such as tracking and/or monitoring of one or more dynamic targets. A remote fusion center fuses the information provided by these sensors so that a final estimate of certain target characteristics – such as the position – is expected to possess much improved quality. In this paper, we pursue learning-based approaches for estimation and fusion of target states in longhaul sensor networks. In particular, we consider learning based on various implementations of artificial neural networks (ANNs). Finally, the joint effect of (i)more » imperfect communication condition, namely, link-level loss and delay, and (ii) computation constraints, in the form of low-quality sensor estimates, on ANN-based estimation and fusion, is investigated by means of analytical and simulation studies.« less

Engineering a self-sufficient Mycobacterium tuberculosis CYP130 by gene fusion with the reductase-domain of CYP102A1 from Bacillus megaterium.

PubMed

Ortega Ugalde, Sandra; Luirink, Rosa A; Geerke, Daan P; Vermeulen, Nico P E; Bitter, Wilbert; Commandeur, Jan N M

2018-03-01

CYP130 belongs to the subset of cytochrome P450s from Mycobacterium tuberculosis (Mtb) that have been structurally characterized. Despite several efforts for its functional characterization, CYP130 is still considered an orphan enzyme for which no endogenous or exogenous substrate has been identified. In addition, functional redox-partners for CYP130 have not been clearly established yet, hampering the elucidation of its physiological role. In the present study, a catalytically active fusion protein involving CYP130 and the NADPH reductase-domain of CYP102A1 from Bacillus megaterium was created. By screening a panel of known substrates of human P450s, dextromethorphan N-demethylation was identified as a reaction catalyzed by CYP130. The fusion enzyme showed higher catalytic activity, when compared to CYP130 reconstituted with a selection of non-native redox-partners. Molecular dynamics simulation studies based on the crystal structure of CYP130 revealed two primary docking poses of dextromethorphan within the active site consistent with the experimentally observed N-demethylation reaction during the entire molecular dynamics simulation. The dextromethorphan N-demethylation reaction was strongly inhibited by azole-drugs and maybe applied to identify mechanism-based inhibitors of CYP130. Furthermore, the present active CYP130-fusion protein may facilitate the identification of endogenous substrates from Mtb. Copyright © 2017 Elsevier Inc. All rights reserved.

Self-organizing plasma behavior in multiple grid IEC fusion devices for propulsion

NASA Astrophysics Data System (ADS)

McGuire, Thomas; Dietrich, Carl; Sedwick, Raymond

2004-11-01

Inertial Electrostatic Confinement, IEC, of charged particles for the purpose of producing fusion energy is a low mass alternative to more traditional magnetic and inertial confinement fusion schemes. Experimental fusion production and energy efficiency in IEC devices to date has been hindered by confinement limitations. Analysis of the major loss mechanisms suggests that the low pressure beam-beam interaction regime holds the most promise for improved efficiency operation. Numerical simulation of multiple grid schemes shows greatly increased confinement times over contemporary single grid designs by electrostatic focusing of the ion beams. An analytical model of this focusing is presented. With the increased confinement, beams self-organize from a uniform condition into bunches that oscillate at the bounce frequency. The bunches from neighboring beams are then observed to synchronize with each other. Analysis of the anisotropic collisional dynamics responsible for the synchronization is presented. The importance of focusing and density on the beam dynamics are examined. Further, this synchronization appears to modify the particle distribution so as to maintain the non-maxwellian, beam-like energy profile within a bunch. The ability of synchronization to modify and counter-act the thermalization process is examined analytically at the 2-body interaction level and as a conglomeration of particles via numerical simulation. Detailed description of the experiment under development at MIT to investigate the synchronization phenomenon is presented.

DIII-D research to address key challenges for ITER and fusion energy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Buttery, Richard J.

DIII-D has made significant advances in the scientific basis for fusion energy. The physics mechanism of resonant magnetic perturbation (RMP) edge localized mode (ELM) suppression is revealed as field penetration at the pedestal top, and reduced coil set operation was demonstrated. Disruption runaway electrons were effectively quenched by shattered pellets; runaway dissipation is explained by pitch angle scattering. Modest thermal quench radiation asymmetries are well described NIMROD modeling. With good pedestal regulation and error field correction, low torque ITER baselines have been demonstrated and shown to be compatible with an ITER test blanket module simulator. However performance and long wavelengthmore » turbulence degrade as low rotation and electron heating are approached. The alternative QH mode scenario is shown to be compatible with high Greenwald density fraction, with an edge harmonic oscillation demonstrating good impurity flushing. Discharge optimization guided by the EPED model has discovered a new super H-mode with doubled pedestal height. Lithium injection also led to wider, higher pedestals. On the path to steady state, 1 MA has been sustained fully non inductively with β N = 4 and RMP ELM suppression, while a peaked current profile scenario provides attractive options for ITER and a β N = 5 future reactor. Energetic particle transport is found to exhibit a critical gradient behavior. Scenarios are shown to be compatible with radiative and snowflake diverter techniques. Physics studies reveal that the transition to H mode is locked in by a rise in ion diamagnetic flows. Intrinsic rotation in the plasma edge is demonstrated to arise from kinetic losses. New 3D magnetic sensors validate linear ideal MHD, but identify issues in nonlinear simulations. Detachment, characterized in 2D with sub-eV resolution, reveals a radiation shortfall in simulations. As a result, future facility development targets burning plasma physics with torque free electron heating, the path to steady state with increased off axis currents, and a new divertor solution for fusion reactors.« less

DIII-D research to address key challenges for ITER and fusion energy

DOE PAGES

Buttery, Richard J.

2015-07-29

DIII-D has made significant advances in the scientific basis for fusion energy. The physics mechanism of resonant magnetic perturbation (RMP) edge localized mode (ELM) suppression is revealed as field penetration at the pedestal top, and reduced coil set operation was demonstrated. Disruption runaway electrons were effectively quenched by shattered pellets; runaway dissipation is explained by pitch angle scattering. Modest thermal quench radiation asymmetries are well described NIMROD modeling. With good pedestal regulation and error field correction, low torque ITER baselines have been demonstrated and shown to be compatible with an ITER test blanket module simulator. However performance and long wavelengthmore » turbulence degrade as low rotation and electron heating are approached. The alternative QH mode scenario is shown to be compatible with high Greenwald density fraction, with an edge harmonic oscillation demonstrating good impurity flushing. Discharge optimization guided by the EPED model has discovered a new super H-mode with doubled pedestal height. Lithium injection also led to wider, higher pedestals. On the path to steady state, 1 MA has been sustained fully non inductively with β N = 4 and RMP ELM suppression, while a peaked current profile scenario provides attractive options for ITER and a β N = 5 future reactor. Energetic particle transport is found to exhibit a critical gradient behavior. Scenarios are shown to be compatible with radiative and snowflake diverter techniques. Physics studies reveal that the transition to H mode is locked in by a rise in ion diamagnetic flows. Intrinsic rotation in the plasma edge is demonstrated to arise from kinetic losses. New 3D magnetic sensors validate linear ideal MHD, but identify issues in nonlinear simulations. Detachment, characterized in 2D with sub-eV resolution, reveals a radiation shortfall in simulations. As a result, future facility development targets burning plasma physics with torque free electron heating, the path to steady state with increased off axis currents, and a new divertor solution for fusion reactors.« less

Introduction of Shear-Based Transport Mechanisms in Radial-Axial Hybrid Hall Thruster Simulations

NASA Astrophysics Data System (ADS)

Scharfe, Michelle; Gascon, Nicolas; Scharfe, David; Cappelli, Mark; Fernandez, Eduardo

2007-11-01

Electron diffusion across magnetic field lines in Hall effect thrusters is experimentally observed to be higher than predicted by classical diffusion theory. Motivated by theoretical work for fusion applications and experimental measurements of Hall thrusters, numerical models for the electron transport are implemented in radial-axial hybrid simulations in order to compute the electron mobility using simulated plasma properties and fitting parameters. These models relate the cross-field transport to the imposed magnetic field distribution through shear suppression of turbulence-enhanced transport. While azimuthal waves likely enhance cross field mobility, axial shear in the electron fluid may reduce transport due to a reduction in turbulence amplitudes and modification of phase shifts between fluctuating properties. The sensitivity of the simulation results to the fitting parameters is evaluated and an examination is made of the transportability of these parameters to several Hall thruster devices.

Gyrokinetic continuum simulation of turbulence in a straight open-field-line plasma

DOE PAGES

Shi, E. L.; Hammett, G. W.; Stoltzfus-Dueck, T.; ...

2017-05-29

Here, five-dimensional gyrokinetic continuum simulations of electrostatic plasma turbulence in a straight, open-field-line geometry have been performed using a full- discontinuous-Galerkin approach implemented in the Gkeyll code. While various simplifications have been used for now, such as long-wavelength approximations in the gyrokinetic Poisson equation and the Hamiltonian, these simulations include the basic elements of a fusion-device scrape-off layer: localised sources to model plasma outflow from the core, cross-field turbulent transport, parallel flow along magnetic field lines, and parallel losses at the limiter or divertor with sheath-model boundary conditions. The set of sheath-model boundary conditions used in the model allows currentsmore » to flow through the walls. In addition to details of the numerical approach, results from numerical simulations of turbulence in the Large Plasma Device, a linear device featuring straight magnetic field lines, are presented.« less

Formation Algorithms and Simulation Testbed

NASA Technical Reports Server (NTRS)

Wette, Matthew; Sohl, Garett; Scharf, Daniel; Benowitz, Edward

2004-01-01

Formation flying for spacecraft is a rapidly developing field that will enable a new era of space science. For one of its missions, the Terrestrial Planet Finder (TPF) project has selected a formation flying interferometer design to detect earth-like planets orbiting distant stars. In order to advance technology needed for the TPF formation flying interferometer, the TPF project has been developing a distributed real-time testbed to demonstrate end-to-end operation of formation flying with TPF-like functionality and precision. This is the Formation Algorithms and Simulation Testbed (FAST) . This FAST was conceived to bring out issues in timing, data fusion, inter-spacecraft communication, inter-spacecraft sensing and system-wide formation robustness. In this paper we describe the FAST and show results from a two-spacecraft formation scenario. The two-spacecraft simulation is the first time that precision end-to-end formation flying operation has been demonstrated in a distributed real-time simulation environment.

Adapting the RoboCup Simulation for Autonomous Vehicle Team Information Fusion and Decision Making Experimentation

DTIC Science & Technology

2010-06-01

researchers outside the government to produce the kinds of algorithms and software that would easily transition into solutions for teams of autonomous ... vehicles for military scenarios. To accomplish this, we began modifying the RoboCup soccer game step-by-step to incorporate rules that simulate these

[Effect of image fusion technology of radioactive particles implantation before and after the planning target and dosimetry].

PubMed

Jiang, Y L; Yu, J P; Sun, H T; Guo, F X; Ji, Z; Fan, J H; Zhang, L J; Li, X; Wang, J J

2017-08-01

Objective: To compare the post-implant target volumes and dosimetric evaluation with pre-plan, the gross tumor volume(GTV) by CT image fusion-based and the manual delineation of target volume in CT guided radioactive seeds implantation. Methods: A total of 10 patients treated under CT-guidance (125)I seed implantation during March 2016 to April 2016 were analyzed in Peking University Third Hospital.All patients underwent pre-operative CT simulation, pre-operative planning, implantation seeds, CT scanning after seed implantation and dosimetric evaluation of GTV.In every patient, post-implant target volumes were delineated by both two methods, and were divided into two groups. Group 1: image fusion pre-implantation simulation and post-operative CT image, then the contours of GTV were automatically performed by brachytherapy treatment planning system; Group 2: the contouring of the GTV on post-operative CT image were performed manually by three senior radiation oncologists independently. The average of three data was sets. Statistical analyses were performed using SPSS software, version 3.2.0. The paired t -test was used to compare the target volumes and D(90) parameters in two modality. Results: In Group 1, average volume of GTV in post-operation group was 12-167(73±56) cm(3). D(90) was 101-153 (142±19)Gy. In Group 2, they were 14-186(80±58)cm(3) and 96-146(122±16) Gy respectively. In both target volumes and D(90), there was no statistical difference between pre-operation and post-operation in Group 1.The D(90) was slightly lower than that of pre-plan group, but there was no statistical difference ( P =0.142); in Group 2, between pre-operation and post-operation group, there was a significant statistical difference in the GTV ( P =0.002). The difference of D(90) was similarly ( P <0.01). Conclusion: The method of delineation of post-implant GTV through fusion pre-implantation simulation and post-operative CT scan images, the contours of GTV are automatically performed by brachytherapy treatment planning system appears to have improved more accuracy, reproducibility and convenience than manual delineation of target volume by maximum reduce the interference from artificial factor and metal artifacts. Further work and more cases are required in the future.

Experimental Evidence of Kinetic Effects in Indirect-Drive Inertial Confinement Fusion Hohlraums

NASA Astrophysics Data System (ADS)

Shan, L. Q.; Cai, H. B.; Zhang, W. S.; Tang, Q.; Zhang, F.; Song, Z. F.; Bi, B.; Ge, F. J.; Chen, J. B.; Liu, D. X.; Wang, W. W.; Yang, Z. H.; Qi, W.; Tian, C.; Yuan, Z. Q.; Zhang, B.; Yang, L.; Jiao, J. L.; Cui, B.; Zhou, W. M.; Cao, L. F.; Zhou, C. T.; Gu, Y. Q.; Zhang, B. H.; Zhu, S. P.; He, X. T.

2018-05-01

We present the first experimental evidence supported by simulations of kinetic effects launched in the interpenetration layer between the laser-driven hohlraum plasma bubbles and the corona plasma of the compressed pellet at the Shenguang-III prototype laser facility. Solid plastic capsules were coated with carbon-deuterium layers; as the implosion neutron yield is quenched, DD fusion yield from the corona plasma provides a direct measure of the kinetic effects inside the hohlraum. An anomalous large energy spread of the DD neutron signal (˜282 keV ) and anomalous scaling of the neutron yield with the thickness of the carbon-deuterium layers cannot be explained by the hydrodynamic mechanisms. Instead, these results can be attributed to kinetic shocks that arise in the hohlraum-wall-ablator interpenetration region, which result in efficient acceleration of the deuterons (˜28.8 J , 0.45% of the total input laser energy). These studies provide novel insight into the interactions and dynamics of a vacuum hohlraum and near-vacuum hohlraum.