Sample records for future division site
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Chromosome segregation drives division site selection in Streptococcus pneumoniae.
van Raaphorst, Renske; Kjos, Morten; Veening, Jan-Willem
2017-07-18
Accurate spatial and temporal positioning of the tubulin-like protein FtsZ is key for proper bacterial cell division. Streptococcus pneumoniae (pneumococcus) is an oval-shaped, symmetrically dividing opportunistic human pathogen lacking the canonical systems for division site control (nucleoid occlusion and the Min-system). Recently, the early division protein MapZ was identified and implicated in pneumococcal division site selection. We show that MapZ is important for proper division plane selection; thus, the question remains as to what drives pneumococcal division site selection. By mapping the cell cycle in detail, we show that directly after replication both chromosomal origin regions localize to the future cell division sites, before FtsZ. Interestingly, Z-ring formation occurs coincidently with initiation of DNA replication. Perturbing the longitudinal chromosomal organization by mutating the condensin SMC, by CRISPR/Cas9-mediated chromosome cutting, or by poisoning DNA decatenation resulted in mistiming of MapZ and FtsZ positioning and subsequent cell elongation. Together, we demonstrate an intimate relationship between DNA replication, chromosome segregation, and division site selection in the pneumococcus, providing a simple way to ensure equally sized daughter cells.
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Mitotic Cortical Waves Predict Future Division Sites by Encoding Positional and Size Information.
Xiao, Shengping; Tong, Cheesan; Yang, Yang; Wu, Min
2017-11-20
Dynamic spatial patterns such as traveling waves could theoretically encode spatial information, but little is known about whether or how they are employed by biological systems, especially higher eukaryotes. Here, we show that concentric target or spiral waves of active Cdc42 and the F-BAR protein FBP17 are invoked in adherent cells at the onset of mitosis. These waves predict the future sites of cell divisions and represent the earliest known spatial cues for furrow assembly. Unlike interphase waves, the frequencies and wavelengths of the mitotic waves display size-dependent scaling properties. While the positioning role of the metaphase waves requires microtubule dynamics, spindle and microtubule-independent inhibitory signals are propagated by the mitotic waves to ensure the singularity of furrow formation. Taken together, we propose that metaphase cortical waves integrate positional and cell size information for division-plane specification in adhesion-dependent cytokinesis. Copyright © 2017 Elsevier Inc. All rights reserved.
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LocZ Is a New Cell Division Protein Involved in Proper Septum Placement in Streptococcus pneumoniae
Holečková, Nela; Molle, Virginie; Buriánková, Karolína; Benada, Oldřich; Kofroňová, Olga; Ulrych, Aleš; Branny, Pavel
2014-01-01
ABSTRACT How bacteria control proper septum placement at midcell, to guarantee the generation of identical daughter cells, is still largely unknown. Although different systems involved in the selection of the division site have been described in selected species, these do not appear to be widely conserved. Here, we report that LocZ (Spr0334), a newly identified cell division protein, is involved in proper septum placement in Streptococcus pneumoniae. We show that locZ is not essential but that its deletion results in cell division defects and shape deformation, causing cells to divide asymmetrically and generate unequally sized, occasionally anucleated, daughter cells. LocZ has a unique localization profile. It arrives early at midcell, before FtsZ and FtsA, and leaves the septum early, apparently moving along with the equatorial rings that mark the future division sites. Consistently, cells lacking LocZ also show misplacement of the Z-ring, suggesting that it could act as a positive regulator to determine septum placement. LocZ was identified as a substrate of the Ser/Thr protein kinase StkP, which regulates cell division in S. pneumoniae. Interestingly, homologues of LocZ are found only in streptococci, lactococci, and enterococci, indicating that this close phylogenetically related group of bacteria evolved a specific solution to spatially regulate cell division. PMID:25550321
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Berezuk, Alison M; Goodyear, Mara; Khursigara, Cezar M
2014-08-22
In Escherichia coli, FtsK is a large integral membrane protein that coordinates chromosome segregation and cell division. The N-terminal domain of FtsK (FtsKN) is essential for division, and the C terminus (FtsKC) is a well characterized DNA translocase. Although the function of FtsKN is unknown, it is suggested that FtsK acts as a checkpoint to ensure DNA is properly segregated before septation. This may occur through modulation of protein interactions between FtsKN and other division proteins in both the periplasm and cytoplasm; thus, a clear understanding of how FtsKN is positioned in the membrane is required to characterize these interactions. The membrane topology of FtsKN was initially determined using site-directed reporter fusions; however, questions regarding this topology persist. Here, we report a revised membrane topology generated by site-directed fluorescence labeling. The revised topology confirms the presence of four transmembrane segments and reveals a newly identified periplasmic loop between the third and fourth transmembrane domains. Within this loop, four residues were identified that, when mutated, resulted in the appearance of cellular voids. High resolution transmission electron microscopy of these voids showed asymmetric division of the cytoplasm in the absence of outer membrane invagination or visible cell wall ingrowth. This uncoupling reveals a novel role for FtsK in linking cell envelope septation events and yields further evidence for FtsK as a critical checkpoint of cell division. The revised topology of FtsKN also provides an important platform for future studies on essential interactions required for this process. © 2014 by The American Society for Biochemistry and Molecular Biology, Inc.
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Environmental Implementation Plan
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1993-03-15
The purpose of the Environmental Implementation Plan (EIP) is to show the current and future (five years) environmental plans from individual site organizations and divisions, as well as site environmental programs and initiatives which are designed to protect the environment and meet or exceed changing environmental/regulatory requirements. Communicating with site organizations, departments, and committees is essential in making the site`s environmental-planning process work. The EIP gives the site the what, when, how, and why for environmental requirements. Through teamwork and proactive planning, a partnership for environmental excellence is formed to achieve the site vision for SRS to become the recognizedmore » model for Environmental Excellence in the Department of Energy`s Nuclear Weapons Complex.« less
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Environmental Implementation Plan
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1993-03-15
The purpose of the Environmental Implementation Plan (EIP) is to show the current and future (five years) environmental plans from individual site organizations and divisions, as well as site environmental programs and initiatives which are designed to protect the environment and meet or exceed changing environmental/regulatory requirements. Communicating with site organizations, departments, and committees is essential in making the site's environmental-planning process work. The EIP gives the site the what, when, how, and why for environmental requirements. Through teamwork and proactive planning, a partnership for environmental excellence is formed to achieve the site vision for SRS to become the recognizedmore » model for Environmental Excellence in the Department of Energy's Nuclear Weapons Complex.« less
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... Logistics Division, Including On-Site Leased Workers From Prologistix and Employment Staffing Solutions... 19, 2010, applicable to workers of CEVA Freight, LLC, Dell Logistics Division, including on-site..., North Carolina location of CEVA Freight, LLC, Dell Logistics Division. The Department has determined...
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Genetic Dissection of DivIVA Functions in Listeria monocytogenes.
Kaval, Karan Gautam; Hauf, Samuel; Rismondo, Jeanine; Hahn, Birgitt; Halbedel, Sven
2017-12-15
DivIVA is a membrane binding protein that clusters at curved membrane regions, such as the cell poles and the membrane invaginations occurring during cell division. DivIVA proteins recruit many other proteins to these subcellular sites through direct protein-protein interactions. DivIVA-dependent functions are typically associated with cell growth and division, even though species-specific differences in the spectrum of DivIVA functions and their causative interaction partners exist. DivIVA from the Gram-positive human pathogen Listeria monocytogenes has at least three different functions. In this bacterium, DivIVA is required for precise positioning of the septum at midcell, it contributes to the secretion of autolysins required for the breakdown of peptidoglycan at the septum after the completion of cell division, and it is essential for flagellar motility. While the DivIVA interaction partners for control of division site selection are well established, the proteins connecting DivIVA with autolysin secretion or swarming motility are completely unknown. We set out to identify divIVA alleles in which these three DivIVA functions could be separated, since the question of the degree to which the three functions of L. monocytogenes DivIVA are interlinked could not be answered before. Here, we identify such alleles, and our results show that division site selection, autolysin secretion, and swarming represent three discrete pathways that are independently influenced by DivIVA. These findings provide the required basis for the identification of DivIVA interaction partners controlling autolysin secretion and swarming in the future. IMPORTANCE DivIVA of the pathogenic bacterium Listeria monocytogenes is a central scaffold protein that influences at least three different cellular processes, namely, cell division, protein secretion, and bacterial motility. How DivIVA coordinates these rather unrelated processes is not known. We here identify variants of L. monocytogenes DivIVA, in which these functions are separated from each other. These results have important implications for the models explaining how DivIVA interacts with other proteins. Copyright © 2017 American Society for Microbiology.
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Research Networks Map | Division of Cancer Prevention
The Division of Cancer Prevention supports major scientific collaborations and research networks at more than 100 sites across the United States. Seven Major Programs' sites are shown on this map. | The Division of Cancer Prevention supports major scientific collaborations and research networks at more than 100 sites across the United States.
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PBP2b plays a key role in both peripheral growth and septum positioning in Lactococcus lactis.
David, Blandine; Duchêne, Marie-Clémence; Haustenne, Gabrielle Laurie; Pérez-Núñez, Daniel; Chapot-Chartier, Marie-Pierre; De Bolle, Xavier; Guédon, Eric; Hols, Pascal; Hallet, Bernard
2018-01-01
Lactococcus lactis is an ovoid bacterium that forms filaments during planktonic and biofilm lifestyles by uncoupling cell division from cell elongation. In this work, we investigate the role of the leading peptidoglycan synthase PBP2b that is dedicated to cell elongation in ovococci. We show that the localization of a fluorescent derivative of PBP2b remains associated to the septal region and superimposed with structural changes of FtsZ during both vegetative growth and filamentation indicating that PBP2b remains intimately associated to the division machinery during the whole cell cycle. In addition, we show that PBP2b-negative cells of L. lactis are not only defective in peripheral growth; they are also affected in septum positioning. This septation defect does not simply result from the absence of the protein in the cell growth machinery since it is also observed when PBP2b-deficient cells are complemented by a catalytically inactive variant of PBP2b. Finally, we show that round cells resulting from β-lactam treatment are not altered in septation, suggesting that shape elongation as such is not a major determinant for selection of the division site. Altogether, we propose that the specific PBP2b transpeptidase activity at the septum plays an important role for tagging future division sites during L. lactis cell cycle.
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RanGAP1 is a continuous marker of the Arabidopsis cell division plane
Xu, Xianfeng Morgan; Zhao, Qiao; Rodrigo-Peiris, Thushani; Brkljacic, Jelena; He, Chao Sylvia; Müller, Sabine; Meier, Iris
2008-01-01
In higher plants, the plane of cell division is faithfully predicted by the preprophase band (PPB). The PPB, a cortical ring of microtubules and F-actin, disassembles upon nuclear-envelope breakdown. During cytokinesis, the expanding cell plate fuses with the plasma membrane at the cortical division site, the site of the former PPB. The nature of the “molecular memory” that is left behind by the PPB and is proposed to guide the cell plate to the cortical division site is unknown. RanGAP is the GTPase activating protein of the small GTPase Ran, which provides spatial information for nucleocytoplasmic transport and various mitotic processes in animals. Here, we show that, in dividing root cells, Arabidopsis RanGAP1 concentrates at the PPB and remains associated with the cortical division site during mitosis and cytokinesis, requiring its N-terminal targeting domain. In a fass/ton2 mutant, which affects PPB formation, RanGAP1 recruitment to the PPB site is lost, while its PPB retention is microtubule-independent. RanGAP1 persistence at the cortical division site, but not its initial accumulation at the PPB requires the 2 cytokinesis-regulating kinesins POK1 and POK2. Depletion of RanGAP by inducible RNAi leads to oblique cell walls and cell-wall stubs in root cell files, consistent with cytokinesis defects. We propose that Arabidopsis RanGAP, a continuous positive protein marker of the plant division plane, has a role in spatial signaling during plant cell division. PMID:19011093
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The Maryland Division of Correction hospice program.
Boyle, Barbara A
2002-10-01
The Maryland Division of Correction houses 24,000 inmates in 27 geographically disparate facilities. The inmate population increasingly includes a frail, elderly component, as well as many inmates with chronic or progressive diseases. The Division houses about 900 human immunodeficiency virus (HIV)-positive detainees, almost one quarter with an acquired immune deficiency syndrome (AIDS) diagnosis. A Ryan White Special Project of National Significance (SPNS) grant and the interest of a community hospice helped transform prison hospice from idea to reality. One site is operational and a second site is due to open in the future. Both facilities serve only male inmates, who comprise more than 95% of Maryland's incarcerated. "Medical parole" is still the preferred course for terminally ill inmates; a number have been sent to various local community inpatient hospices or released to the care of their families. There will always be some who cannot be medically paroled, for whom hospice is appropriate. Maryland's prison hospice program requires a prognosis of 6 months or less to live, a do-not-resuscitate (DNR) order and patient consent. At times, the latter two of these have been problematic. Maintaining the best balance between security requirements and hospice services to dying inmates takes continual communication, coordination and cooperation. Significant complications in some areas remain: visitation to dying inmates by family and fellow prisoners; meeting special dietary requirements; what role, if any, will be played by inmate volunteers. Hospice in Maryland's Division of Correction is a work in progress.
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DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1994-09-06
The Muskego Sanitary Landfill site is situated within the City of Muskego, Waukesha County, in the State of Wisconsin. Muskego Sanitary Landfill is a former sand and gravel pit which received unspecified types and amounts of municipal and industrial wastes over a period of approximately 25 years. Muskego Sanitary Landfill site is a public health hazard because in the past some nearby residents probably drank private well water containing site-related contamination. The groundwater around the site might pose a future public health hazard if no further action were taken to clean up the site. Ambient air near Muskego Sanitary Landfillmore » is an indeterminate public health hazard. Wisconsin's Department of Health and Social Services, Division of Health (DOH) recommends the continued monitoring of groundwater in the vicinity of the site.« less
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Preventing High Blood Pressure
... commit" type="submit" value="Submit" /> Related CDC Web Sites Division for Heart Disease and Stroke Prevention ... commit" type="submit" value="Submit" /> Related CDC Web Sites Division for Heart Disease and Stroke Prevention ...
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Cholesterol Facts and Statistics
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WISEWOMAN: Frequently Asked Questions
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NASA Astrophysics Data System (ADS)
Todd, James; Legler, David; Piotrowicz, Stephen; Raymond, Megan; Smith, Emily; Tedesco, Kathy; Thurston, Sidney
2017-04-01
The Ocean Observing and Monitoring Division (OOMD, formerly the Climate Observation Division) of the National Oceanic and Atmospheric Administration (NOAA) Climate Program Office provides long-term, high-quality global observations, climate information and products for researchers, forecasters, assessments and other users of environmental information. In this context, OOMD-supported activities serve a foundational role in an enterprise that aims to advance 1) scientific understanding, 2) monitoring and prediction of climate and 3) understanding of potential impacts to enable a climate resilient society. Leveraging approximately 50% of the Global Ocean Observing System, OOMD employs an internationally-coordinated, multi-institution global strategy that brings together data from multiple platforms including surface drifting buoys, Argo profiling floats, flux/transport moorings (RAMA, PIRATA, OceanSITES), GLOSS tide gauges, SOOP-XBT and SOOP-CO2, ocean gliders and repeat hydrographic sections (GO-SHIP). OOMD also engages in outreach, education and capacity development activities to deliver training on the social-economic applications of ocean data. This presentation will highlight recent activities and plans for 2017 and beyond.
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Gravity and the orientation of cell division
NASA Technical Reports Server (NTRS)
Helmstetter, C. E.
1997-01-01
A novel culture system for mammalian cells was used to investigate division orientations in populations of Chinese hamster ovary cells and the influence of gravity on the positioning of division axes. The cells were tethered to adhesive sites, smaller in diameter than a newborn cell, distributed over a nonadhesive substrate positioned vertically. The cells grew and divided while attached to the sites, and the angles and directions of elongation during anaphase, projected in the vertical plane, were found to be random with respect to gravity. However, consecutive divisions of individual cells were generally along the same axis or at 90 degrees to the previous division, with equal probability. Thus, successive divisions were restricted to orthogonal planes, but the choice of plane appeared to be random, unlike the ordered sequence of cleavage orientations seen during early embryo development.
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Stoops, William W; Sigmon, Stacey C; Evans, Suzette M
2016-08-01
This is an introduction to the special issue "50th Anniversary of APA Division 28: The Past, Present, and Future of Psychopharmacology and Substance Abuse." Taken together, the scholarly contributions included in this special issue serve as a testament to the important work conducted by our colleagues over the past five decades. Division 28 and its members have advanced and disseminated knowledge on the behavioral effects of drugs, informed efforts to prevent and treat substance abuse, and influenced education and policy issues more generally. As past and current leaders of the division, we are excited to celebrate 50 years of Division 28 and look forward to many more successful decades for our division and its members. (PsycINFO Database Record (c) 2016 APA, all rights reserved).
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NASA Astrophysics Data System (ADS)
Manuse, Sylvie; Jean, Nicolas L.; Guinot, Mégane; Lavergne, Jean-Pierre; Laguri, Cédric; Bougault, Catherine M.; Vannieuwenhze, Michael S.; Grangeasse, Christophe; Simorre, Jean-Pierre
2016-06-01
Accurate placement of the bacterial division site is a prerequisite for the generation of two viable and identical daughter cells. In Streptococcus pneumoniae, the positive regulatory mechanism involving the membrane protein MapZ positions precisely the conserved cell division protein FtsZ at the cell centre. Here we characterize the structure of the extracellular domain of MapZ and show that it displays a bi-modular structure composed of two subdomains separated by a flexible serine-rich linker. We further demonstrate in vivo that the N-terminal subdomain serves as a pedestal for the C-terminal subdomain, which determines the ability of MapZ to mark the division site. The C-terminal subdomain displays a patch of conserved amino acids and we show that this patch defines a structural motif crucial for MapZ function. Altogether, this structure-function analysis of MapZ provides the first molecular characterization of a positive regulatory process of bacterial cell division.
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... Chemical Corporation Wacker Polymers Division a Subsidiary of Wacker Chemie AG Including On-Site Leased.... and Yoh Managed Staffing South Brunswick, NJ; Wacker Chemical Corporation Wacker Polymers Division a... of Wacker Chemical Corporation, Wacker Polymers Division, a subsidiary of Wacker Chemie AG, including...
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The Western Ecology Division (WED) is one of four ecological effects divisions of the National Health and Environmental Effects Research Laboratory. The four divisions are distributed bio-geographically. WED's mission is 1) to provide EPA with national scientific leadership for t...
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Alaska Department of Revenue - Tax Division - License Search Page
Alaska Web Site? Tax State of Alaska Tax Types Forms Reports Online Services About Tax Alaska Department of Revenue - Tax Division Department of Revenue > Tax Division > Tax Types > Search Permits
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Alaska Department of Revenue - Tax Division - Charitable Gaming Page
Alaska Web Site? Tax State of Alaska Tax Types Forms Reports Online Services About Tax Alaska Department of Revenue - Tax Division Department of Revenue > Tax Division > Tax Types > Charitable
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-01-05
... Division, Product Engineering, Including On-Site Leased Workers of Aerotek Contract Engineering, Allied Personnel Services, Eastern Engineering, Hobbie Professional Services, Mccallion Staffing Specialists, Peak Technical Services, Inc., Yoh Engineering, and Clarke Consulting, Inc., Bethlehem, PA; Amended Certification...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-10-26
... Management, Inc., Corporate Service Group, Information Technology (IT) Division, Including On-Site Leased... Information Management, Inc., Corporate Service Group, Information Technology (IT) Division, including on-site... location of Iron Mountain Information Management, Inc., Corporate Service Group, Information Technology (IT...
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Bayless, E. Randall; Arihood, Leslie D.; Fowler, Kathleen K.
2011-01-01
The Green Valley reclaimed coal refuse site, near Terre Haute, Ind., was mined for coal from 1948 to 1963. Subsurface coal was cleaned and sorted at land surface, and waste material was deposited over the native glacial till. Approximately 2.7 million cubic yards of waste was deposited over 159 acres (92.3 hectares) in tailings ponds and gob piles. During 1993, the Indiana Department of Natural Resources, Division of Reclamation, improved the site by grading gob piles, filling tailings ponds, and covering the refuse with a layer of glacial drift. During 2008, the Division of Reclamation and U.S. Geological Survey initiated a cooperative investigation to characterize the hydrogeology of the site and construct a calibrated groundwater flow model that could be used to simulate the results of future remedial actions. In support of the modeling, a data-collection network was installed at the Green Valley site to measure weather components, geophysical properties, groundwater levels, and stream and seep flow. Results of the investigation indicate that (1) there is negligible overland flow from the site, (2) the prevailing groundwater-flow direction is from northeast to southwest, with a much smaller drainage to the northeast, (3) there is not a direct hydraulic connection between the refuse and West Little Sugar Creek, (4) about 24 percent of the groundwater recharge emerges through seeps, and water from the seeps evaporates or eventually flows to West Little Sugar Creek and the Green Valley Mine Pond, and (5) about 72 percent of groundwater recharge moves vertically downward from the coal refuse into the till and follows long, slow flow paths to eventual dischage points.
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Maple, Jodi; Møller, Simon G
2007-10-01
Plastid division represents a fundamental biological process essential for plant development; however, the molecular basis of symmetric plastid division is unclear. AtMinE1 plays a pivotal role in selection of the plastid division site in concert with AtMinD1. AtMinE1 localises to discrete foci in chloroplasts and interacts with AtMinD1, which shows a similar localisation pattern. Here, we investigate the importance of Min protein complex formation during the chloroplast division process. Dissection of the assembly of the Min protein complex and determination of the interdependency of complex assembly and localisation in planta allow us to present a model of the molecular basis of selection of the division site in plastids. Moreover, functional analysis of AtMinE1 in bacteria demonstrates the level of functional conservation and divergence of the plastidic MinE proteins.
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-07-19
... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-72,585] Whirlpool Corporation, Evansville Division, Including On-Site Leased Workers From Andrews International, Inc., M.H. Equipment, and Kenco Logistics Services, LLC, Evansville, IN; Amended Certification Regarding Eligibility To Apply for...
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-12
... software and related services including quality assurance and learning products, marketing, product development, marketing and administration. The company reports that on-site leased workers from Managed..., Santa Clara, California, and the Everett, Washington locations of Agilent Technologies, EEsof Division...
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-01-24
... Administrative Division Including On-Site Leased Workers From JFC Including Teleworkers Located Throughout the United States Reporting to Etters, PA; Amended Certification Regarding Eligibility To Apply for Worker.... 2273, the Department of Labor issued a Certification of Eligibility To Apply for Worker Adjustment...
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Search the Division of Finance site DOF State of Alaska Finance Home Content Area Accounting Charge Cards IRIS HRM Login LearnAlaska SFOA SharePoint Site Vendor Self Service (VSS) Content Area Accounting Dunayski, Accounting Services Lead Danielle Meier, State E-Travel Manager Stephanie Church, IRIS Financial
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-07-24
.... The Department has determined that these workers were sufficiently under the control of the subject..., Stevens Point, Wisconsin Division, Including On-Site Leased Workers From ABR, Aerotek, and Manpower, Stevens Point, WI; Amended Certification Regarding Eligibility To Apply for Worker Adjustment Assistance...
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Federal Register 2010, 2011, 2012, 2013, 2014
2013-08-27
... these workers were sufficiently under the control of the subject firm to be considered leased workers...; Springfield, Missouri Division Including On-site Leased Workers From Penmac Personnel Services and GCA Services Group Springfield, Missouri; Amended Certification Regarding Eligibility to Apply for Worker...
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-01-06
... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-62,282] National Starch and Chemical Company Specialty Starches Division Including On-Site Leased Workers From Page Employment, Island... Adjustment Assistance on December 13, 2007, applicable to workers of National Starch and Chemical Company...
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-05-17
... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-81,299] Kohler Company, Malvern Division, Including On-Site Leased Workers From Manpower Staffing and Dow Cleaning Services, Malvern, AR; Amended Certification Regarding Eligibility To Apply for Worker Adjustment Assistance In accordance with...
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Federal Register 2010, 2011, 2012, 2013, 2014
2013-08-08
... amending this certification to include all workers of Delphi Automotive Systems, LLC, Product and Service..., LLC, Products and Service Solutions Division, Including On-Site Leased Workers From Bartech Workforce Management, Kokomo, Indiana; Amended Certification Regarding Eligibility To Apply for Worker Adjustment...
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-09-07
... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-73,762] Rain Bird Corporation, Arizona Molding Division Including On-Site Leased Workers From Lumea Staffing Services, Tri-State Staffing Services and Remedy Staffing (AKA Select Staffing) Tucson, AZ; Amended Certification Regarding Eligibility...
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ERIC Educational Resources Information Center
Dance, Frank E. X.; And Others
This paper reports on the Futuristic Priorities Division members' recommendations and priorities concerning the impact of the future on communication and on the speech communication discipline. The recommendations and priorities are listed for two subgroups: The Communication Needs and Rights of Mankind; and Future Communication Technologies:…
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Kidney Biopsy Adequacy: A Metric-based Study.
Ferrer, German; Andeen, Nicole K; Lockridge, Joseph; Norman, Douglas; Foster, Bryan R; Houghton, Donald C; Troxell, Megan L
2018-06-05
There are differences in renal biopsy yield related to on-site evaluation, tissue division, and operator, among others. To understand these variations, we collected adequacy-associated data (%cortex, glomeruli, arteries, length) from consecutive native and allograft kidney biopsies over a 22-month period. In total, 1332 biopsies (native: 873, allograft: 459) were included, 617 obtained by nephrologists, 663 by radiologists, and 559 with access to on-site division. Proceduralists with access to on-site evaluation had significantly lower inadequacy rates and better division of tissue for light microscopy (LM), immunofluorescence, and electron microscopy than those without access to on-site evaluation. Radiologists in our region were significantly less likely to have access to on-site evaluation than nephrologists. On multivariate analysis for native kidney biopsies, the effect of having a radiologist perform the biopsy and having access to on-site division were both significant predictors of obtaining greater calculated amount of cortex for LM. Despite the trend for radiologists to obtain more tissue in general, biopsies from nephrologists contained a greater percentage of cortex and were more likely to be considered adequate for LM (native kidney inadequacy rate for LM: 1.11% vs. 5.41%, P=0.0086). Biopsies in which inadequate or marginal cortical tissue was submitted for LM had only minor decreases in the amount of cortex submitted for immunofluorescence and electron microscopy, revealing an opportunity for improved specimen triaging when limited tissue is obtained. In conclusion, both on-site evaluation/division and proceduralist significantly affect quantitative kidney biopsy metrics, which in turn affects the pathologist's ability to render an accurate diagnosis with appropriate prognostic information for the patient and treating nephrologist.
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PROFILE OF THE GULF ECOLOGY DIVISION, UNITED STATES ENVIRONMENTAL PROTECTION AGENCY
A history of the man-made island on which the Gulf Ecology Division is located,from its origin in 1876 to the present day (2007). Contains a synopsis of current research and future plans of the division.
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-08-23
... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-81,317] Dana Holding Corporation, Power Technologies Group Division, Including On-Site Leased Workers From Manpower, Milwaukee, WI; Notice... investigation resulted in a negative determination based on the findings that the subject firm did not shift...
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-01
... Engineering Division, Including B&C Distribution Center, Including On-Site Leased Workers From B&C Services, Inc., Barberton, OH; Amended Certification Regarding Eligibility To Apply for Worker Adjustment... Department of Labor issued a Certification of Eligibility to Apply for Worker Adjustment Assistance on...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-03-15
... undated planning and organizing products. The review shows that on August 21, 2008, a certification of..., Consumer and Office Products Division, Including On-Site Leased Workers From Pro-Tel People, Sidney, NY; Amended Certification Regarding Eligibility To Apply for Worker Adjustment Assistance In accordance with...
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-08-13
... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-70,232; TA-W-70,232A] Halliburton Company, Duncan Mfg., Including On-Site Leased Workers from Express Personnel, Clayton Personnel Service, and Manpower Planning, Duncan, OK; Halliburton Company, Technology and Engineering Division, Finance and Administration Division, Duncan, OK;...
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-07-26
... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-71,494] Johns Manville; Engineered Products Division, Including On-Site Leased Workers From Volt Workforce Solutions; Spartanburg, SC; Notice of Revised Determination on Reconsideration By application dated May 2, 2010, a petitioner requested administrative reconsideration of the...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-05-11
... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-75,099] West, A Thomson Reuters Business, Thomson Reuters Legal Division, Including On-Site Leased Workers From ADECCO, Albuquerque, NM... Adjustment Assistance (TAA) applicable to workers and former workers of West, A Thomson Reuters Business...
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7 CFR 2003.18 - Functional organization of RHS.
Code of Federal Regulations, 2010 CFR
2010-01-01
... Property Management Division, and Single Family Housing Centralized Servicing Center in St. Louis, Mo. (i... credit reports, and, site development. (ii) Multi-Family Housing Portfolio Management Division. Headed by... the management and servicing of the nationwide Multi-Family Housing programs. The Division implements...
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Conceptual design of new metrology laboratories for the National Physical Laboratory, United Kingdom
NASA Astrophysics Data System (ADS)
Manning, Christopher J.
1994-10-01
The National Physical Laboratory is planning to house the Division of Mechanical and Optical Metrology and the Division of Material Metrology in a new purpose built laboratory building on its site at Teddington, London, England. The scientific staff were involved in identifying and agreeing the vibration performance requirements of the conceptual design. This was complemented by an extensive surgery of vibration levels within the existing facilities and ambient vibration studies at the proposed site. At one end of the site there is significant vibration input from road traffic. Some of the test equipment is also in itself a source of vibration input. These factors, together with normal occupancy inputs, footfalls and door slams, and a highly serviced building led to vibration being dominant in influencing the structural form. The resulting structural concept comprises three separate structural elements for vibration and geotechnical reasons. The laboratories most sensitive to disturbance by vibration are located at the end of the site farthest from local roads on a massive ground bearing slab. Less sensitive laboratories and those containing vibration sources are located on a massive slab in deep, piled foundations. A common central plant area is located alongside on its own massive slab. Medium sensitivity laboratories and offices are located at first floor level on a reinforced concrete suspended floor of maximum stiffness per unit mass. The whole design has been such as to permit upgrading of areas, eg office to laboratory; laboratory to `high sensitivity' laboratory, to cater for changes in future use of the building.
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-07-10
..., Instrumentation and Speciality Controls Division, West Chicago, IL; Amended Certification Regarding Eligibility To... Nationals Controls Corporation, Instrumentation and Specialty Control Division, West Chicago, Illinois. The... Corporation, Instrumentation and Specialty Control Division, West Chicago, Illinois, separated from employment...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-06-17
... and Veneer, Colville Tribal Enterprise Corporation Wood Products Division, Including On-Site Workers..., applicable to workers of Colville Indian Plywood and Veneer, Colville Tribal Enterprise Corporation Wood... Wood Products Division, to perform construction, electrical and operational maintenance support...
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Mission analysis report for single-shell tank leakage mitigation
DOE Office of Scientific and Technical Information (OSTI.GOV)
Cruse, J.M.
1994-09-01
This document provides an analysis of the leakage mitigation mission applicable to past and potential future leakage from the Hanford Site`s 149 single-shell high-level waste tanks. This mission is a part of the overall missions of the Westinghouse Hanford Company Tank Waste Remediation System division to remediate the tank waste in a safe and acceptable manner. Systems engineers principles are being applied to this effort. Mission analysis supports early decision making by clearly defining program objectives. This documents identifies the initial conditions and acceptable final conditions, defines the programmatic and physical interfaces and constraints, estimates the resources to carry outmore » the mission, and establishes measures of success. The results of the mission analysis provide a consistent basis for subsequent systems engineering work.« less
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-07-07
... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-73,555] Hewlett-Packard Company Division of Corporate Administration and Shared Services Including On-Site Leased Workers From Manpower and Including Workers Off-Site From Various States in the United States Reporting to Omaha, NE; Including Employees of Hewlett-Packard Company...
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-12
... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-70,151] Smith and Nephew, Inc... November 5, 2009, applicable to workers of Smith and Nephew, Inc., Wound Management-Largo Division, Largo... workers leased from Adecco were employed on-site at the Largo, Florida location of Smith and Nephew, Inc...
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Naef, Olivier
2012-01-01
This short paper presents the abstracts of the different presentations during 10. Freiburger Symposium 2011 der SCG-Division Industrielle Chemie: Technology Progress, Success key for our production sites held Thursday and Friday, September 29 and 30, 2011 at the Ecole d'ingénieurs et d'architectes de Fribourg (Switzerland).
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-08-02
... Window Division, Including On-Site Leased Workers of Nicolet Staffing, Hawkins, WI; Notice of Negative... imports of wood- and aluminum- clad windows and patio doors did not contribute to worker group separations... of wood- and aluminum-clad windows and patio doors during 2007, 2008, January through April 2008, and...
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Federal Register 2010, 2011, 2012, 2013, 2014
2013-02-06
... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-81,755] Thomson Reuters, Finance Operations & Technology Division, Including On-Site Leased Workers From Adecco; Eagan, MN; Amended Certification Regarding Eligibility To Apply for Worker Adjustment Assistance In accordance with Section 223 of the Trade Act of 1974, as amended (`...
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77 FR 56870 - Notice of Continuation of Certification
Federal Register 2010, 2011, 2012, 2013, 2014
2012-09-14
... [TA-W-80,308] Roseburg Forest Products, Composite Panel Division, Including On-Site Leased Workers of Robert Half, Orangeburg, SC [TA-W-80,308A] Roseburg Forest Products, Composite Panel Division, Including... (TAA) applicable to workers and former workers of Roseburg Forest Products, Composite Panel Division...
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76 FR 10395 - BreconRidge Manufacturing Solutions, Now Known as Sanmina-SCI Corporation, Division...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-02-24
... Solutions, Now Known as Sanmina-SCI Corporation, Division Optoelectronic and Microelectronic Design and Manufacturing, a Subsidiary of Sanmina-SCI Corporation, Including On- Site Leased Workers From Kelly Services... Manufacturing Solutions, now known as Sanmina-SCI Corporation, Division Optoelectronic and Microelectronic...
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Honda, Takashi; Morimoto, Daichi; Sako, Yoshihiko; Yoshida, Takashi
2018-05-17
Previously, we showed that DNA replication and cell division in toxic cyanobacterium Microcystis aeruginosa are coordinated by transcriptional regulation of cell division gene ftsZ and that an unknown protein specifically bound upstream of ftsZ (BpFz; DNA-binding protein to an upstream site of ftsZ) during successful DNA replication and cell division. Here, we purified BpFz from M. aeruginosa strain NIES-298 using DNA-affinity chromatography and gel-slicing combined with gel electrophoresis mobility shift assay (EMSA). The N-terminal amino acid sequence of BpFz was identified as TNLESLTQ, which was identical to that of transcription repressor LexA from NIES-843. EMSA analysis using mutant probes showed that the sequence GTACTAN 3 GTGTTC was important in LexA binding. Comparison of the upstream regions of lexA in the genomes of closely related cyanobacteria suggested that the sequence TASTRNNNNTGTWC could be a putative LexA recognition sequence (LexA box). Searches for TASTRNNNNTGTWC as a transcriptional regulatory site (TRS) in the genome of M. aeruginosa NIES-843 showed that it was present in genes involved in cell division, photosynthesis, and extracellular polysaccharide biosynthesis. Considering that BpFz binds to the TRS of ftsZ during normal cell division, LexA may function as a transcriptional activator of genes related to cell reproduction in M. aeruginosa, including ftsZ. This may be an example of informality in the control of bacterial cell division.
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Cytokinesis-Based Constraints on Polarized Cell Growth in Fission Yeast
Bohnert, K. Adam; Gould, Kathleen L.
2012-01-01
The rod-shaped fission yeast Schizosaccharomyces pombe, which undergoes cycles of monopolar-to-bipolar tip growth, is an attractive organism for studying cell-cycle regulation of polarity establishment. While previous research has described factors mediating this process from interphase cell tips, we found that division site signaling also impacts the re-establishment of bipolar cell growth in the ensuing cell cycle. Complete loss or targeted disruption of the non-essential cytokinesis protein Fic1 at the division site, but not at interphase cell tips, resulted in many cells failing to grow at new ends created by cell division. This appeared due to faulty disassembly and abnormal persistence of the cell division machinery at new ends of fic1Δ cells. Moreover, additional mutants defective in the final stages of cytokinesis exhibited analogous growth polarity defects, supporting that robust completion of cell division contributes to new end-growth competency. To test this model, we genetically manipulated S. pombe cells to undergo new end take-off immediately after cell division. Intriguingly, such cells elongated constitutively at new ends unless cytokinesis was perturbed. Thus, cell division imposes constraints that partially override positive controls on growth. We posit that such constraints facilitate invasive fungal growth, as cytokinesis mutants displaying bipolar growth defects formed numerous pseudohyphae. Collectively, these data highlight a role for previous cell cycles in defining a cell's capacity to polarize at specific sites, and they additionally provide insight into how a unicellular yeast can transition into a quasi-multicellular state. PMID:23093943
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Responding Logistically to Future Natural and Man-Made Disasters and Catastrophes
2008-03-15
Logistics Operations, Plans and Exercises, Distribution Management and Property Management. Each competency has associated roles, missions and...professional development. LMD’s Distribution Management Division (DMD) Within the LMD, FEMA also created the Distribution Management Division (DMD...to stock in anticipation of future disasters. A Distribution Management Strategy Working Group was formed with Federal, private and nongovernmental
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DOE Office of Scientific and Technical Information (OSTI.GOV)
None
1969-01-01
This is the second edition of the Division of Isotopes Development project summaries. It presents a short summary of objectives, results, and future plans for each research or development project sponsored by the Division within each of eight program areas.
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Environmental Implementation Plan
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1994-02-01
The Environmental Implementation Plan (EIP) is a dynamic long-range environmental-protection plan for SRS. The EIP communicates the current and future (five year) environmental plans from individual organizations and divisions as well as site environmental initiatives which are designed to protect the environment and meet or exceed compliance with changing environmental/ regulatory requirements. Communication with all site organizations is essential for making the site environmental planning process work. Demonstrating environmental excellence is a high priority embodied in DOE and WSRC policy. Because of your support and participation in the three EIP initiatives; Reflections, Sectional Revision, and Integrated Planning, improvements are beingmore » made to the EIP and SRS environmental protection programs. I appreciate the ``Partnership in Environmental Excellence`` formed by the environmental coordinators and professionals who work daily toward our goal of compliance and environmental excellence. I look forward to seeing continued success and improvement in our environmental protection programs through combined efforts of all site organizations to protect our employees, the public health, and the environment. Together, we will achieve our site vision for SRS to be the recognized model for Environmental Excellence in the DOE Nuclear Weapons Complex.« less
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Federal Register 2010, 2011, 2012, 2013, 2014
2013-05-15
... Doing Business as Duluth Hardboard Plant, Specialty Manufacturing Division, a Subsidiary of Koch... business as Duluth Hardboard Plant, Specialty Manufacturing Division, a subsidiary of Koch Industries... Division, a subsidiary of Koch Industries, including on-site leased workers of DS&E Company, Duluth...
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Takeuchi, Miyuki; Karahara, Ichirou; Kajimura, Naoko; Takaoka, Akio; Murata, Kazuyoshi; Misaki, Kazuyo; Yonemura, Shigenobu; Staehelin, L. Andrew; Mineyuki, Yoshinobu
2016-01-01
The preprophase band (PPB) is a cytokinetic apparatus that determines the site of cell division in plants. It originates as a broad band of microtubules (MTs) in G2 and narrows to demarcate the future division site during late prophase. Studies with fluorescent probes have shown that PPBs contain F-actin during early stages of their development but become actin depleted in late prophase. Although this suggests that actins contribute to the early stages of PPB formation, how actins contribute to PPB-MT organization remains unsolved. To address this question, we used electron tomography to investigate the spatial relationship between microfilaments (MFs) and MTs at different stages of PPB assembly in onion cotyledon epidermal cells. We demonstrate that the PPB actins observed by fluorescence microscopy correspond to short, single MFs. A majority of the MFs are bound to MTs, with a subset forming MT-MF-MT bridging structures. During the later stages of PPB assembly, the MF-mediated links between MTs are displaced by MT-MT linkers as the PPB MT arrays mature into tightly packed MT bundles. On the basis of these observations, we propose that the primary function of actins during PPB formation is to mediate the initial bundling of the PPB MTs. PMID:27053663
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ERIC Educational Resources Information Center
Bird, Bruce
This paper discusses the development of two World Wide Web sites at Anne Arundel Community College (Maryland). The criteria for the selection of hardware and software for Web site development that led to the decision to use Microsoft FrontPage 98 are described along with its major components and features. The discussion of the Science Division Web…
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-07-16
... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-81,045; TA-W-81,045A] Dow Jones & Company, Inc., Dow Jones Content Services Division, Including On-Site Workers From Aerotek, Inc., Princeton, NJ; Generate, Inc., a Subsidiary of Dow Jones & Company, Inc., Boston, MA; Amended Certification Regarding Eligibility To Apply for Worker...
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Federal Register 2010, 2011, 2012, 2013, 2014
2013-07-02
... USA, LLC. The Department has determined that these workers were sufficiently under the control of the..., FCI USA, LLC, Americas Division, a Subsidiary of FCI SA, Including On-Site Leased Workers From... Eligibility To Apply for Worker Adjustment Assistance In accordance with Section 223 of the Trade Act of 1974...
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Lead from the center. How to manage divisions dynamically.
Raynor, M E; Bower, J L
2001-05-01
Conventional wisdom holds that a company's divisions should be given almost total autonomy--especially under conditions of uncertainty--because they are closer to emerging technologies, customers, and competitors than corporate headquarters could ever be. But research from Michael Raynor and Joseph Bower suggests that the corporate office should be more, not less, directive in turbulent markets. Rapid changes in an industry make it difficult to predict where and when synergies among divisions might emerge. With so many possibilities and such uncertainty, companies can't afford to sacrifice their ability to flexibly execute business strategy. Corporate headquarters must play an active role in defining the scope of division-level strategy, the authors say, so that divisions do not act in ways that undermine opportunities to collaborate in the future. But neither can companies afford to sacrifice the competitiveness of their divisions as stand-alone businesses. In creating corporate-level strategic flexibility, a corporate office must balance the need for divisional autonomy now with the potential need for cooperation in the future. Through an examination of four corporations--Sprint, WPP, Teradyne, and Viacom--the authors challenge traditional approaches to diversification in which a company's divisions are either related (they share resources and collaborate) or unrelated (they compete for resources and operate as stand-alone businesses). They argue that companies should adopt a dynamic approach to cooperation among divisions, enabling varying degrees of relatedness between divisions depending on strategic circumstances. The authors offer four tactics to help executives manage divisions dynamically.
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-05
... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-71,602] Cooper Tools--Sumter, Cooper Tools Divisions, a Subsidiary of Cooper Industries, Inc., Including On-Site Leased Workers From... January 26, 2010, applicable to workers of Cooper Tools--Sumter, Cooper Tools Division, a subsidiary of...
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French Atomic Energy Commission Decommissioning Programme and Feedback Experience - 12230
DOE Office of Scientific and Technical Information (OSTI.GOV)
Guiberteau, Ph.; Nokhamzon, J.G.
Since the French Atomic and Alternatives Energy Commission (CEA) was founded in 1945 to carry out research programmes on use of nuclear, and its application France has set up and run various types of installations: research or prototypes reactors, process study or examination laboratories, pilot installations, accelerators, nuclear power plants and processing facilities. Some of these are currently being dismantled or must be dismantled soon so that the DEN, the Nuclear Energy Division, can construct new equipment and thus have available a range of R and D facilities in line with the issues of the nuclear industry of the future.more » Since the 1960's and 1970's in all its centres, the CEA has acquired experience and know-how through dismantling various nuclear facilities. The dismantling techniques are nowadays operational, even if sometimes certain specific developments are necessary to reduce the cost of operations. Thanks to availability of techniques and guarantees of dismantling programme financing now from two dedicated funds, close to euro 15,000 M for the next thirty years, for current or projected dismantling operations, the CEA's Nuclear Energy Division has been able to develop, when necessary, its immediate dismantling strategy. Currently, nearly thirty facilities are being dismantled by the CEA's Nuclear Energy Division operational units with industrial partners. Thus the next decade will see completion of the dismantling and radioactive clean-up of the Grenoble site and of the facilities on the Fontenay-aux-Roses site. By 2016, the dismantling of the UP1 plant at Marcoule, the largest dismantling work in France, will be well advanced, with all the process equipment dismantled. After an overview of the French regulatory framework, the paper will describe the DD and R (Decontamination Decommissioning and Remediation) strategy, programme and feedback experience inside the CEA's Nuclear Energy Division. A special feature of dismantling operations at the CEA comes from the diversity of facilities to be dismantled, which are predominantly research facilities and therefore have no series advantage. There is tremendous operating feedback, however. For more than twenty years in all its centres, the CEA has acquired experience and know-how through dismantling research reactors or critical models and laboratories or plants. The dismantling techniques are nowadays operational, even if sometimes certain specific developments are necessary to reduce the cost of operations. Thanks to availability of techniques and guarantees of dismantling programme financing from two dedicated funds, close to euro 15,000 Millions for the next thirty years, for current or projected dismantling operations, the Nuclear Energy Division has been able to develop, when necessary, its immediate dismantling strategy. Currently, nearly thirty facilities are being dismantled by the CEA's Nuclear Energy Division operational units with industrial partners. Thus the next decade will see completion of the dismantling and radioactive clean-up of the Grenoble site and of the facilities on the Fontenay-aux-Roses site. By 2020, the dismantling of the UP1 plant at Marcoule, one of the largest dismantling works in the world, will be well advanced, with all the process equipment dismantled. (authors)« less
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40 CFR 52.2630 - Prevention of significant deterioration of air quality.
Code of Federal Regulations, 2010 CFR
2010-07-01
.... Skie, EPA, dated May 18, 1989, Charles A. Collins, Administrator of the Air Quality Divisions stated: * * * The Division, will, as a matter of practice, utilize the “Guideline on Air Quality Models” as revised, including Supplement A, in all PSD permit application reviews. The Division will utilize any future...
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Punting Our Future: College Athletics and Admissions
ERIC Educational Resources Information Center
Fried, Barbara H.
2007-01-01
Jeremiads about intercollegiate sports have been around for about as long as intercollegiate sports. In recent decades, critics have focused on headlines about abuses involving the big-time, NCAA Division IA sports teams, citing elite Division III schools and Ivy League schools as the poster children for reform. Unlike Division IA programs, whose…
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-11-26
... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-81,880: TA-A-81,880A] RG Steel Wheeling, LLC, Wheeling Office, A Division Of RG Steel, LLC, Including On-Site Leased Workers From Pro Unlimited and Green Energy Initiatives LLC, Including Workers Whose Wages Were Reported Through Severstal Wheeling, Wheeling, WV: Mountain State...
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Search the Division of Finance site DOF State of Alaska Finance Home Content Area Accounting Charge Cards Paystubs) Fringe Benefits Mission Statement The mission of the Division of Finance is to provide accounting
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17 CFR 140.91 - Delegation of authority to the Director of the Division of Trading and Markets.
Code of Federal Regulations, 2011 CFR
2011-04-01
... Director of the Division of Trading and Markets. 140.91 Section 140.91 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION ORGANIZATION, FUNCTIONS, AND PROCEDURES OF THE COMMISSION Functions § 140.91 Delegation of authority to the Director of the Division of Trading and Markets. (a) The...
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17 CFR 140.91 - Delegation of authority to the Director of the Division of Trading and Markets.
Code of Federal Regulations, 2012 CFR
2012-04-01
... Director of the Division of Trading and Markets. 140.91 Section 140.91 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION ORGANIZATION, FUNCTIONS, AND PROCEDURES OF THE COMMISSION Functions § 140.91 Delegation of authority to the Director of the Division of Trading and Markets. (a) The...
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Celebrating 65 Years of a Dynamic Organization for School Librarians
ERIC Educational Resources Information Center
Woolls, Blanche
2016-01-01
The American Association of School Librarians (AASL) as an American Library Association division is sixty-five years young in 2016. This article describes the AASL as a division of the American Library Association (ALA). The author presents: (1) Early Days in ALA; (2) AASL as a Division; (3) AASL's Future; and (4) Commemorating the Past by Paying…
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17 CFR 140.91 - Delegation of authority to the Director of the Division of Trading and Markets.
Code of Federal Regulations, 2010 CFR
2010-04-01
... Director of the Division of Trading and Markets. 140.91 Section 140.91 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION ORGANIZATION, FUNCTIONS, AND PROCEDURES OF THE COMMISSION Functions § 140.91 Delegation of authority to the Director of the Division of Trading and Markets. (a) The...
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Feng, Zhonghui; Okada, Satoshi; Cai, Guoping; Zhou, Bing; Bi, Erfei
2015-01-01
MLC1 is a haploinsufficient gene encoding the essential light chain for Myo1, the sole myosin‑II heavy chain in the budding yeast Saccharomyces cerevisiae. Mlc1 defines an essential hub that coordinates actomyosin ring function, membrane trafficking, and septum formation during cytokinesis by binding to IQGAP, myosin‑II, and myosin‑V. However, the mechanism of how Mlc1 is targeted to the division site during the cell cycle remains unsolved. By constructing a GFP‑tagged MLC1 under its own promoter control and using quantitative live‑cell imaging coupled with yeast mutants, we found that septin ring and actin filaments mediate the targeting of Mlc1 to the division site before and during cytokinesis, respectively. Both mechanisms contribute to and are collectively required for the accumulation of Mlc1 at the division site during cytokinesis. We also found that Myo1 plays a major role in the septin‑dependent Mlc1 localization before cytokinesis, whereas the formin Bni1 plays a major role in the actin filament–dependent Mlc1 localization during cytokinesis. Such a two‑tiered mechanism for Mlc1 localization is presumably required for the ordered assembly and robustness of cytokinesis machinery and is likely conserved across species. PMID:25631819
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DCP's Early Detection Research Guides Future Science | Division of Cancer Prevention
Early detection research funded by the NCI's Division of Cancer Prevention has positively steered both public health and clinical outcomes, and set the stage for findings in the next generation of research. |
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ER-mitochondria contacts couple mtDNA synthesis with mitochondrial division in human cells.
Lewis, Samantha C; Uchiyama, Lauren F; Nunnari, Jodi
2016-07-15
Mitochondrial DNA (mtDNA) encodes RNAs and proteins critical for cell function. In human cells, hundreds to thousands of mtDNA copies are replicated asynchronously, packaged into protein-DNA nucleoids, and distributed within a dynamic mitochondrial network. The mechanisms that govern how nucleoids are chosen for replication and distribution are not understood. Mitochondrial distribution depends on division, which occurs at endoplasmic reticulum (ER)-mitochondria contact sites. These sites were spatially linked to a subset of nucleoids selectively marked by mtDNA polymerase and engaged in mtDNA synthesis--events that occurred upstream of mitochondrial constriction and division machine assembly. Our data suggest that ER tubules proximal to nucleoids are necessary but not sufficient for mtDNA synthesis. Thus, ER-mitochondria contacts coordinate licensing of mtDNA synthesis with division to distribute newly replicated nucleoids to daughter mitochondria. Copyright © 2016, American Association for the Advancement of Science.
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Interstate 73 economic impact analysis : a summary and synthesis.
DOT National Transportation Integrated Search
1994-01-01
The Transportation Planning Division (TPD) of the Virginia Department of Transportation (VDOT) is currently considering seven corridors along which VDOT may build the future Interstate 73. The division describes these seven routes and their variants ...
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Sandia National Laboratories, California Environmental Management System program manual.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Larsen, Barbara L.
2012-03-01
The Sandia National Laboratories, California (SNL/CA) Environmental Management System (EMS) Program Manual documents the elements of the site EMS Program. The SNL/CA EMS Program conforms to the International Standard on Environmental Management Systems, ISO 14001:2004and Department of Energy (DOE) Order 436.1. Sandia National Laboratories, California (SNL/CA) has maintained functional environmental programs to assist with regulatory compliance for more than 30 years. During 2005, these existing programs were rolled into a formal environmental management system (EMS) that expands beyond the traditional compliance focus to managing and improving environmental performance and stewardship practices for all site activities. An EMS is a setmore » of inter-related elements that represent a continuing cycle of planning, implementing, evaluating, and improving processes and actions undertaken to achieve environmental policy and goals. The SNL/CA EMS Program conforms to the International Standard for Environmental Management Systems, ISO 14001:2004 (ISO 2004). The site first received ISO 14001 certification in September 2006 and recertification in 2009. SNL/CA's EMS Program is applicable to the Sandia, Livermore site only. Although SNL/CA operates as one organizational division of the overall Sandia National Laboratories, the EMS Program is site-specific, with site-specific objectives and targets. SNL/CA (Division 8000) benefits from the organizational structure as it provides corporate level policies, procedures, and standards, and established processes that connect to and support elements of the SNL/CA EMS Program. Additionally, SNL/CA's EMS Program benefits from two corporate functional programs (Facilities Energy and Water Resource Management and Fleet Services programs) that maintain responsibility for energy management and fleet services for all Sandia locations. Each EMS element is further enhanced with site-specific processes and standards. Division 8000 has several groups operating at Sandia National Laboratories, New Mexico (SNL/NM). Although these groups, from an organizational perspective, are part of Division 8000, they are managed locally and fall under the environmental requirements specific to their New Mexico location. The New Mexico groups in Division 8000 follow the corporate EMS Program for New Mexico operations.« less
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R and E: Communications and Intelligent Systems Division (LC)
NASA Technical Reports Server (NTRS)
Emerson, Dawn C.; Miranda, Felix A.
2015-01-01
This presentation is intended for the Ohio Federal Research Network's Centers of Excellence. The presentation provides an overview of the Communications and Intelligent Systems Division including current research and engineering work as well as future technology needs.
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33 CFR 279.11 - Responsibilities.
Code of Federal Regulations, 2010 CFR
2010-07-01
... DEFENSE RESOURCE USE: ESTABLISHMENT OF OBJECTIVES § 279.11 Responsibilities. Division engineers will... preparation to insure timely compliance on development of resource use objectives. Future budget submissions and expenditures of construction and operation and maintenance funds will be reviewed by division...
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Saaki, Terrens N V; Strahl, Henrik; Hamoen, Leendert W
2018-02-20
Chemoreceptors are localized at the cell poles of Escherichia coli and other rod-shaped bacteria. Over the years different mechanisms have been put forward to explain this polar localization; from stochastic clustering, membrane curvature driven localization, interactions with the Tol-Pal complex, to nucleoid exclusion. To evaluate these mechanisms, we monitored the cellular localization of the aspartate chemoreceptor Tar in different deletion mutants. We did not find any indication for either stochastic cluster formation or nucleoid exclusion. However, the presence of a functional Tol-Pal complex appeared to be essential to retain Tar at cell poles. Interestingly, Tar still accumulated at midcell in tol and in pal deletion mutants. In these mutants, the protein appears to gather at the base of division septa, a region characterised by strong membrane curvature. Chemoreceptors, like Tar, form trimer-of-dimers that bend the cell membrane due to a rigid tripod structure. The curvature approaches the curvature of the cell membrane generated during cell division, and localization of chemoreceptor tripods at curved membrane areas is therefore energetically favourable as it lowers membrane tension. Indeed, when we introduced mutations in Tar that abolish the rigid tripod structure, the protein was no longer able to accumulate at midcell or cell poles. These findings favour a model where chemoreceptor localization in E. coli is driven by strong membrane curvature and association with the Tol-Pal complex. Importance Bacteria have exquisite mechanisms to sense and to adapt to the environment they live in. One such mechanism involves the chemotaxis signal transduction pathway, in which chemoreceptors specifically bind certain attracting or repelling molecules and transduce the signals to the cell. In different rod-shaped bacteria, these chemoreceptors localize specifically to cell poles. Here, we examined the polar localization of the aspartate chemoreceptor Tar in E. coli , and found that membrane curvature at cell division sites and the Tol-Pal protein complex, localize Tar at cell division sites, the future cell poles. This study shows how membrane curvature can guide localization of proteins in a cell. Copyright © 2018 American Society for Microbiology.
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US Army battery needs -- Present and future
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hamlen, R.P.; Christopher, H.A.; Gilman, S.
1995-07-01
The purpose of this paper is to describe the needs of the US Army for silent portable power sources, both in the near and longer term future. As a means of doing this, the programs of the Power Sources Division of the Army Research Laboratory will be discussed. The six program areas in which the Power Sources Division is engaged are: primary batteries, rechargeable batteries, reserve/fuze batteries, pulse batteries and capacitors, fuel cells, and thermophotovoltaic power generation.
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Fischer-Friedrich, Elisabeth; Friedrich, Benjamin M; Gov, Nir S
2012-02-01
In many bacterial species, the protein FtsZ forms a cytoskeletal ring that marks the future division site and scaffolds the division machinery. In rod-shaped bacteria, most frequently membrane-attached FtsZ rings or ring fragments are reported and occasionally helices. By contrast, axial FtsZ clusters have never been reported. In this paper, we investigate theoretically how dynamic FtsZ aggregates align in rod-shaped bacteria. We study systematically different physical mechanisms that affect the alignment of FtsZ polymers using a computational model that relies on autocatalytic aggregation of FtsZ filaments at the membrane. Our study identifies a general tool kit of physical and geometrical mechanisms by which rod-shaped cells align biopolymer aggregates. Our analysis compares the relative impact of each mechanism on the circumferential alignment of FtsZ as observed in rod-shaped bacteria. We determine spontaneous curvature of FtsZ polymers and axial confinement of FtsZ on the membrane as the strongest factors. Including Min oscillations in our model, we find that these stabilize axial and helical clusters on short time scales, but promote the formation of an FtsZ ring at the cell middle at longer times. This effect could provide an explanation to the long standing puzzle of transiently observed oscillating FtsZ helices in Escherichia coli cells prior to cell division.
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ADP Analysis project for the Human Resources Management Division
NASA Technical Reports Server (NTRS)
Tureman, Robert L., Jr.
1993-01-01
The ADP (Automated Data Processing) Analysis Project was conducted for the Human Resources Management Division (HRMD) of NASA's Langley Research Center. The three major areas of work in the project were computer support, automated inventory analysis, and an ADP study for the Division. The goal of the computer support work was to determine automation needs of Division personnel and help them solve computing problems. The goal of automated inventory analysis was to find a way to analyze installed software and usage on a Macintosh. Finally, the ADP functional systems study for the Division was designed to assess future HRMD needs concerning ADP organization and activities.
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Hazardous Waste Cleanup: Wyeth Holdings Corporation in Princeton Junction, New Jersey
BASF, formerly American Cyanamid Corporation (ACC) Agricultural Division, is a 683 acre site, located at the intersection of Quakerbridge Rd and US Route 1 in Princeton Junction, NJ. BASF bought the operations of ACC Agricultural Division from American
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Hazardous Waste Cleanup: Fisher Scientific Chemical Division in Fair Lawn, New Jersey
Fisher Scientific Chemical Division occupies a 10-acre site at 1 Reagent Lane in the Fair Lawn Industrial Park, New Jersey. Since 1955, Fisher has formulated, distilled, repackaged and distributed high-purity, laboratory-grade reagents and solvents.
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Overview of NASA Glenn Research Center's Communications and Intelligent Systems Division
NASA Technical Reports Server (NTRS)
Miranda, Felix A.
2016-01-01
The Communications and Intelligent Systems Division provides expertise, plans, conducts and directs research and engineering development in the competency fields of advanced communications and intelligent systems technologies for application in current and future aeronautics and space systems.
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Annual Report, Reservoir Control Center, Southwestern Division (1989)
1990-01-01
Division in the water quality field . This provides for water quality objectives being included as an effective part of our total water management...WES) selected Canyon Lake as a research field site for developing techniques to evaluate the impacts associated with installation of hydropower at Corps...term continuous goals of this Division, and consequently the Water Management Branch, in the water quality field . (1) To obtain sufficient water
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The Future of Conflict Resolution in Africa and the Role of the Organization of African Unity (OAU)
1998-06-01
SUBJECT TERMS Peace Operations, Peacekeeping, Africa, Organization of African Unity, Mechanism, Preventive diplomacy, conflict management 17...establishing a Division of Conflict Management . The division would be located within the OAU, but independent from the Defense Commission established under...chairman informed of all actions envisaged or already undertaken. • the setting up of a Division on Conflict Management with the appropriate resources
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The Creation of a Pediatric Hospital Medicine Dashboard: Performance Assessment for Improvement.
Fox, Lindsay Anne; Walsh, Kathleen E; Schainker, Elisabeth G
2016-07-01
Leaders of pediatric hospital medicine (PHM) recommended a clinical dashboard to monitor clinical practice and make improvements. To date, however, no programs report implementing a dashboard including the proposed broad range of metrics across multiple sites. We sought to (1) develop and populate a clinical dashboard to demonstrate productivity, quality, group sustainability, and value added for an academic division of PHM across 4 inpatient sites; (2) share dashboard data with division members and administrations to improve performance and guide program development; and (3) revise the dashboard to optimize its utility. Division members proposed a dashboard based on PHM recommendations. We assessed feasibility of data collection and defined and modified metrics to enable collection of comparable data across sites. We gathered data and shared the results with division members and administrations. We collected quarterly and annual data from October 2011 to September 2013. We found comparable metrics across all sites for descriptive, productivity, group sustainability, and value-added domains; only 72% of all quality metrics were tracked in a comparable fashion. After sharing the data, we saw increased timeliness of nursery discharges and an increase in hospital committee participation and grant funding. PHM dashboards have the potential to guide program development, mobilize faculty to improve care, and demonstrate program value to stakeholders. Dashboard implementation at other institutions and data sharing across sites may help to better define and strengthen the field of PHM by creating benchmarks and help improve the quality of pediatric hospital care. Copyright © 2016 by the American Academy of Pediatrics.
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Communications and Intelligent Systems Division - Division Overview
NASA Technical Reports Server (NTRS)
Miranda, Felix A.
2017-01-01
This presentation provides an overview of the research and engineering work being performed in the competency fields of advanced communications and intelligent systems with emphasis on advanced technologies, architecture definition,and systems development for application in current and future aeronautics and space communications systems.
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Communications and Intelligent Systems Division - Division Overview
NASA Technical Reports Server (NTRS)
Miranda, Felix A.
2017-01-01
This presentation provides an overview of the research and engineering work being performed in the competency fields of advanced communications and intelligent systems with emphasis on advanced technologies, architecture definition, and systems development for application in current and future aeronautics and space communications systems.
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Multichannel demultiplexer/demodulator technologies for future satellite communication systems
NASA Technical Reports Server (NTRS)
Ivancic, William D.; Budinger, James M.; Staples, Edward J.; Abramovitz, Irwin; Courtois, Hector A.
1992-01-01
NASA-Lewis' Space Electronics Div. supports ongoing research in advanced satellite communication architectures, onboard processing, and technology development. Recent studies indicate that meshed VSAT (very small aperture terminal) satellite communication networks using FDMA (frequency division multiple access) uplinks and TDMA (time division multiplexed) downlinks are required to meet future communication needs. One of the critical advancements in such a satellite communication network is the multichannel demultiplexer/demodulator (MCDD). The progress is described which was made in MCDD development using either acousto-optical, optical, or digital technologies.
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NASA's ultraviolet astrophysics branch - The next decade
NASA Technical Reports Server (NTRS)
Welsh, Barry Y.; Kaplan, Michael
1992-01-01
We review some of the mission concepts currently being considered by NASA's Astrophysics Division to carry out future observations in the 100-3000 Angstrom region. Examples of possible future missions include UV and visible interferometric experiments, a next generation Space Telescope and lunar-based UV instrumentation. In order to match the science objectives of these future missions with new observational techniques, critical technology needs in the ultraviolet regime have been identified. Here we describe how NASA's Astrophysics Division Advanced Programs Branch is attempting to formulate an integrated technology plan called the 'Astrotech 21' program in order to provide the technology base for these astrophysics missions of the 21st century.
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Frenzel, S.A.
1996-01-01
Ninety-one stream sites in central Nebraska were classified into four clusters on the basis of a cluster analysis (TWINSPAN) of macroinvertebrate data. Rapid bioassessment protocol scores for macroinvertebrate species were significantly different among sites grouped by teh first division into two clusters. This division may have distinguished sites on the basis of water-quality imparement. Individual metrics that differed between clusters of sites were the Hilsenhoff Biotic Index, the number of Ephemeroptera, Plecoptera, and Trichoptera (EPT) taxa, and the ratio of individuals in EPT to Chironomidae taxa. Canonical correspondence analysis of 57 of 91 sites showed that stream width, site altitude, latitude, soil permeability, water temperature, and mean annual precipitation were the most important environmental variables describing variance in the species-environment relation. Stream width and soil permeability reflected streamflow characteristics of a site, whereas site altitude and latitude were factors related to general climatic conditions. Mean annual precipitation related to both streamflow and climatic conditions.
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76 FR 76183 - Amended Certification Regarding Eligibility To Apply for Worker Adjustment Assistance
Federal Register 2010, 2011, 2012, 2013, 2014
2011-12-06
... and Kentwood West Plants, Corporate Development Center, Grand Rapids, Michigan. Steelcase, Inc., North America Division, Regional Distribution Center, Grand Rapids, Michigan. Leased Workers From Manpowergroup...., Working On-Site At Steelcase, Inc., North America Division, Kentwood East And Kentwood West Plants...
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Department of Natural Resources logo, color scheme Department of Natural Resources Division of Agriculture Search Search DNR's site DNR State of Alaska Toggle main menu visibility Agriculture Home Programs Asset Disposals Alaska Caps Progam Board of Agriculture & Conservation Farm To School Program Grants
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Federal Register 2010, 2011, 2012, 2013, 2014
2013-09-04
... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-82,379] Abbott Laboratories... February 22, 2013, applicable to workers of Abbott Laboratories, Diagnostic--Hematology division, including... Clara, California location of Abbott Laboratories, Diagnostic--Hematology Division. The Department has...
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Hazardous Waste Cleanup: GM Assembly Division in Linden, New Jersey
The General Motors Assembly Division (GM) site is 35 acres and is located at 1016 West Edgar Road in an area zoned for residential, commercial and manufacturing/industrial uses in Linden, New Jersey. The facility has operated since 1935 as a manufacturing
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Top Department of Administration logo Alaska Department of Administration Division of Finance Search Search the Division of Finance site DOF State of Alaska Finance Home Content Area Accounting Charge Cards You are here Administration / Finance / Travel Travel The Department of Administration administers the
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Los Alamos National Laboratory Prototype Fabrication Division CNM Briefing
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hidalgo, Stephen P.; Keyser, Richard J.
2012-06-18
Prototype Fabrication Division designs, programs, manufactures, and inspects on-site high quality, diverse material parts and components that can be delivered at the pace the customer needs to meet their mission. Our goal is to bring vision to reality in the name of science.
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Yahashiri, Atsushi; Jorgenson, Matthew A; Weiss, David S
2017-07-15
Sporulation-related repeat (SPOR) domains are small peptidoglycan (PG) binding domains found in thousands of bacterial proteins. The name "SPOR domain" stems from the fact that several early examples came from proteins involved in sporulation, but SPOR domain proteins are quite diverse and contribute to a variety of processes that involve remodeling of the PG sacculus, especially with respect to cell division. SPOR domains target proteins to the division site by binding to regions of PG devoid of stem peptides ("denuded" glycans), which in turn are enriched in septal PG by the intense, localized activity of cell wall amidases involved in daughter cell separation. This targeting mechanism sets SPOR domain proteins apart from most other septal ring proteins, which localize via protein-protein interactions. In addition to SPOR domains, bacteria contain several other PG-binding domains that can exploit features of the cell wall to target proteins to specific subcellular sites. Copyright © 2017 American Society for Microbiology.
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Biphasic targeting and cleavage furrow ingression directed by the tail of a myosin II
Fang, Xiaodong; Luo, Jianying; Nishihama, Ryuichi; Wloka, Carsten; Dravis, Christopher; Travaglia, Mirko; Iwase, Masayuki; Vallen, Elizabeth A.
2010-01-01
Cytokinesis in animal and fungal cells utilizes a contractile actomyosin ring (AMR). However, how myosin II is targeted to the division site and promotes AMR assembly, and how the AMR coordinates with membrane trafficking during cytokinesis, remains poorly understood. Here we show that Myo1 is a two-headed myosin II in Saccharomyces cerevisiae, and that Myo1 localizes to the division site via two distinct targeting signals in its tail that act sequentially during the cell cycle. Before cytokinesis, Myo1 localization depends on the septin-binding protein Bni5. During cytokinesis, Myo1 localization depends on the IQGAP Iqg1. We also show that the Myo1 tail is sufficient for promoting the assembly of a “headless” AMR, which guides membrane deposition and extracellular matrix remodeling at the division site. Our study establishes a biphasic targeting mechanism for myosin II and highlights an underappreciated role of the AMR in cytokinesis beyond force generation. PMID:21173112
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Management implications of brood division in Golden-winged Warblers: Chapter 10
Peterson, Sean M.; Streby, Henry M.; Andersen, David E.
2016-01-01
Brood division in the postfledging period is a common avian behavior that is not well understood. Brood division has been reported in Golden-winged Warblers (Vermivora chrysoptera), but it is not known how common this behavior is, whether males and females exhibit different strategies related to parental care and habitat use, or how brood division might influence management strategies. We radiomarked fledglings and monitored divided broods of Golden-winged Warblers from fledging until independence from parental care at three sites in the western Great Lakes region from 2010 to 2012 to assess differences in strategies between male and female parents and to consider possible management implications. Male - and female-reared sub-broods exhibited different space use during the dependent post-fledging period despite similar fledgling survivial, cover-type use, and microhabitat use. By independence, female-reared sub-broods traveled over twice as far from the nest (mean = 461 ± 81) SE m) as male-reared sub-broods (164 ± 41 m). Additionally, female-reared sub-broods traveled over three times as far from the natal patch edge (35 ± 72 m) as male-reared sub-broods (108 ± 36 m). Without accounting for differential space use by male- and female-reared sub-broods, we would have reported broods traveling 292 (± 46 m) from the nest and 214 (± 40m) from the natal patch edge - distances that do not reflect how far females move sub-broods. Parental strategies differ between sexes with regard to movement patterns, and we recommend incorporating the differences in space use between sexes in future management plans for Golden-winged Warblers and other species that employ brood division. Specifically, management actions might be most effective when they are applied at spatial scales large enough to incorporate the habitat requirements of both sexes throughout the entire reproductive season.
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FIELD STUDIES OF GEOMEMBRANE INSTALLATION TECHNIQUES
Fourteen construction sites where geomembranes were being installed were visited to observe subgrade preparation and liner installation techniques. These sites were visited during a study conducted for the U.S. EPA, Solid and Hazardous Waste Research Division. The sites included ...
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Interactive NCORP Map Details Community Research Sites | Division of Cancer Prevention
An interactive map of the NCI Community Oncology Research Program (NCORP) with detailed information on hundreds of community sites that take part in clinical trials is available on the NCORP website. NCORP Map NCORP Community Sites, Minority/Underserved Community Sites, and Research Bases |
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Tsui, Ho-Ching Tiffany; Keen, Susan K; Sham, Lok-To; Wayne, Kyle J; Winkler, Malcolm E
2011-01-01
The Sec translocase pathway is the major route for protein transport across and into the cytoplasmic membrane of bacteria. Previous studies reported that the SecA translocase ATP-binding subunit and the cell surface HtrA protease/chaperone formed a single microdomain, termed "ExPortal," in some species of ellipsoidal (ovococcus) Gram-positive bacteria, including Streptococcus pyogenes. To investigate the generality of microdomain formation, we determined the distribution of SecA and SecY by immunofluorescent microscopy in Streptococcus pneumoniae (pneumococcus), which is an ovococcus species evolutionarily distant from S. pyogenes. In the majority (≥ 75%) of exponentially growing cells, S. pneumoniae SecA (SecA (Spn)) and SecY (Spn) located dynamically in cells at different stages of division. In early divisional cells, both Sec subunits concentrated at equators, which are future sites of constriction. Further along in division, SecA(Spn) and SecY(Spn) remained localized at mid-cell septa. In late divisional cells, both Sec subunits were hemispherically distributed in the regions between septa and the future equators of dividing cells. In contrast, the HtrA (Spn) homologue localized to the equators and septa of most (> 90%) dividing cells, whereas the SrtA(Spn) sortase located over the surface of cells in no discernable pattern. This dynamic pattern of Sec distribution was not perturbed by the absence of flotillin family proteins, but was largely absent in most cells in early stationary phase and in cls mutants lacking cardiolipin synthase. These results do not support the existence of an ExPortal microdomain in S. pneumoniae. Instead, the localization of the pneumococcal Sec translocase depends on the stage of cell division and anionic phospholipid content. Two patterns of Sec translocase distribution, an ExPortal microdomain in certain ovococcus-shaped species like Streptococcus pyogenes and a spiral pattern in rod-shaped species like Bacillus subtilis, have been reported for Gram-positive bacteria. This study provides evidence for a third pattern of Sec localization in the ovococcus human pathogen Streptococcus pneumoniae. The SecA motor and SecY channel subunits of the Sec translocase localize dynamically to different places in the mid-cell region during the division cycle of exponentially growing, but not stationary-phase, S. pneumoniae. Unexpectedly, the S. pneumoniae HtrA (HtrA(Spn)) protease/chaperone principally localizes to cell equators and division septa. The coincident localization of SecA(Spn), SecY (Spn), and HtrA (Spn) to regions of peptidoglycan (PG) biosynthesis in unstressed, growing cells suggests that the pneumococcal Sec translocase directs assembly of the PG biosynthesis apparatus to regions where it is needed during division and that HtrA(Spn) may play a general role in quality control of proteins exported by the Sec translocase.
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Long-range ordered vorticity patterns in living tissue induced by cell division
NASA Astrophysics Data System (ADS)
Rossen, Ninna S.; Tarp, Jens M.; Mathiesen, Joachim; Jensen, Mogens H.; Oddershede, Lene B.
2014-12-01
In healthy blood vessels with a laminar blood flow, the endothelial cell division rate is low, only sufficient to replace apoptotic cells. The division rate significantly increases during embryonic development and under halted or turbulent flow. Cells in barrier tissue are connected and their motility is highly correlated. Here we investigate the long-range dynamics induced by cell division in an endothelial monolayer under non-flow conditions, mimicking the conditions during vessel formation or around blood clots. Cell divisions induce long-range, well-ordered vortex patterns extending several cell diameters away from the division site, in spite of the system’s low Reynolds number. Our experimental results are reproduced by a hydrodynamic continuum model simulating division as a local pressure increase corresponding to a local tension decrease. Such long-range physical communication may be crucial for embryonic development and for healing tissue, for instance around blood clots.
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78 FR 16663 - Agency Information Collection Activities Under OMB Review
Federal Register 2010, 2011, 2012, 2013, 2014
2013-03-18
... COMMODITY FUTURES TRADING COMMISSION Agency Information Collection Activities Under OMB Review AGENCY: Commodity Futures Trading Commission. ACTION: Notice. SUMMARY: In compliance with the Paperwork...: Commodity Futures Trading Commission (``CFTC''), Attention: Gary J. Martinaitis, Division of Market...
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Divison of Environmental Education and Development Fiscal Year 1992 annual report
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1992-12-31
Primary design criterion for this division`s education activities is directly related to meeting the goal of environmental compliance on an accelerated basis and cleanup of the 1989 inventory of inactive sites and facilities by the year 2019. Therefore, the division`s efforts are directed toward stimulating knowledge and capability to achieve the goals while contributing to DOE`s overall goal of increasing scientific, mathematical, and technical literacy and competency. This annual report is divided into: overview, workforce development, academic partnerships, scholarships/fellowships, environmental restoration and waste management employment program, community colleges, outreach, evaluation, and principal DOE contacts.
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Federal Register 2010, 2011, 2012, 2013, 2014
2013-01-15
... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-80,490] Novartis Pharmaceuticals... Healthcare, and Pro Unlimited, East Hanover, NJ and Off-Site Workers of Novartis Pharmaceuticals Corporation..., applicable to workers of Novartis Pharmaceuticals Corporation, Primary Care Business Unit (Sales) Division...
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77 FR 47669 - Employment and Training Administration
Federal Register 2010, 2011, 2012, 2013, 2014
2012-08-09
... DEPARTMENT OF LABOR Employment and Training Administration TA-W-81,446, Wellpoint, Inc., NE Enrollment and Billing Division, Including On-Site Leased Workers From Aerotek, Kelly Services and Populus Group, North Haven, CT; TA-W-81,446A, Wellpoint, Inc., NE Enrollment and Billing Division, Including On...
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77 FR 42341 - Proposal Review Panel for Chemistry; Notice of Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2012-07-18
... NATIONAL SCIENCE FOUNDATION Proposal Review Panel for Chemistry; Notice of Meeting In accordance... announces the following meeting: Name: ChemMatCARS Site Visit, 2011 Awardees by NSF Division of Chemistry.... Carlos Murillo, Program Director, Division of Chemistry, Room 1055, National Science Foundation, 4201...
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-11-03
... Chief, Environmental Enforcement Section, Environment and Natural Resources Division. [FR Doc. 2010... Debtor's Portland Harbor Superfund Site; and (3) natural resource damages and assessment costs, incurred... should be addressed to the Acting Assistant Attorney General, Environment and Natural Resources Division...
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-02-16
... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-72,231] Lonza, Inc., Riverside Plant, Lonza Exclusive Synthesis Section, Custom Manufacturing Division Including On-Site Leased Workers of Lab Support, Aerotek, Job Exchange, and Synerfac; Conshohocken, PA; Notice of Affirmative...
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-01-06
... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-72,231] Lonza, Inc. Riverside Plant; Lonza Exclusive Synthesis Section Custom Manufacturing Division Including On-Site Leased Workers of Lab Support, Aerotek, Job Exchange, and Synerfac; Conshohocken, PA; Notice of Affirmative...
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Lewis materials research and technology: An overview
NASA Technical Reports Server (NTRS)
Grisaffe, Salvatore J.
1987-01-01
The Materials Division at the Lewis Research Center has a long record of contributions to both materials and process technology as well as to the understanding of key high-temperature phenomena. An overview of the division staff, facilities, past history, recent progress, and future interests is presented.
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NASA. Lewis Research Center materials research and technology: An overview
NASA Technical Reports Server (NTRS)
Grisaffe, Salvatore J.
1990-01-01
The Materials Division at the Lewis Research Center has a long record of contributions to both materials and process technology as well as to the understanding of key high-temperature phenomena. This paper overviews the division staff, facilities, past history, recent progress, and future interests.
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LIVING RESOURCES AND THEIR HABITATS ARE THE FOCUS OF THE GULF ECOLOGY DIVISION'S MISSION
This brief article introduces ERF Newsletter readers to the Gulf Ecology Division. Future articles will showcase our estuarine and near-coastal research efforts in areas such as biochemical and cellular toxicology, temporal and spatial scaling of ecological data, reproductive and...
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Parnell, J.M.
1997-01-01
The U.S. Geological Survey (USGS), in cooperation with Aeronautical Systems Center, Environmental Management Directorate, Restoration Division, prepared the Surface- and Ground- Water Monitoring Work Plan for Air Force Plant 85 (AFP 85 or Plant), Columbus, Ohio, under the Air Force Installation Restoration Program to characterize any ground-water, surface-water, and soil contamination that may exist at AFP 85. The USGS began the study in November 1996. The Plant was divided into nine sampling areas, which included some previously investi gated study sites. The investigation activities included the collection and presentation of data taken during drilling and water-quality sampling. Data collection focused on the saturated and unsatur ated zones and surface water. Twenty-three soil borings were completed. Ten monitoring wells (six existing wells and four newly constructed monitoring wells) were selected for water-quality sam pling. Surface-water and streambed-sediment sampling locations were chosen to monitor flow onto and off of the Plant. Seven sites were sampled for both surface-water and streambed-sediment quality. This report presents data on the selected inorganic and organic constituents in soil, ground water, surface water, and streambed sediments at AFP 85. The methods of data collection and anal ysis also are included. Knowledge of the geologic and hydrologic setting could aid Aeronautical Systems Center, Environmental Management Directorate, Restoration Division, and its governing regulatory agencies in future remediation studies.
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77 FR 47670 - Amended Certification Regarding Eligibility To Apply for Worker Adjustment Assistance
Federal Register 2010, 2011, 2012, 2013, 2014
2012-08-09
... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-75,151; TA-W-75,151A] Amended... Reliability Center, A Subsidiary of Navistar International Corporation, Truck Division, Including All On-Site... Reliability Center, a Subsidiary of Navistar International Corporation, Truck Division, 3033 Wayne Trace, Fort...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-06-24
... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-75,033] Indianapolis Metal Center... FEIN 38- 0572515, Including On-Site Leased Workers From Aerotek, Comprehensive Logistics Company, Inc... Metal Center, a division of General Motors Company, including workers whose wages were previously...
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Search the Division of Finance site DOF State of Alaska Finance Home Content Area Accounting Charge Cards Checkbook Online Overview The State of Alaska is publishing information from the statewide accounting system mission of the Division of Finance is to provide accounting, payroll, and travel services for State
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Eileen Dimond, RN, MS | Division of Cancer Prevention
Eileen Dimond is a nurse consultant in the Division of Cancer Prevention. She works with the NCI community oncology programs and the sites that form the community network across the U.S. and in Hawaii with a focus on clinical trial infrastructure and implementation in the community. |
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33 CFR 331.7 - Review procedures.
Code of Federal Regulations, 2010 CFR
2010-07-01
... process, and assist the division engineer in making a decision on the merits of the appeal. The division... engineer will make the decision on the merits of the appeal, and provide any instructions, as appropriate... no case shall any site visit extend the total appeals process beyond twelve months from the date of...
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DOE Office of Scientific and Technical Information (OSTI.GOV)
Hyman, A.A.
1989-09-01
In Caenorhabditis elegans embryos, early blastomeres of the P cell lineage divide successively on the same axis. This axis is a consequence of the specific rotational movement of the pair of centrosomes and nucleus. A laser has been used to perturb the centrosome movements that determine the pattern of early embryonic divisions. The results support a previously proposed model in which a centrosome rotates towards its correct position by shortening of connections, possibly microtubules, between a centrosome and a defined site on the cortex of the embryo.
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1991-09-19
Company) in Torrance, CA; (8) Gnmman Space Electronics Division in Bethpage, NY; (9) Raytheon Services Nevada (RSN) in Las Vegas, NV; (10) Reynolds...10 to 20 minutes long, and spaced 1 or more weeks apart. (S) The accident scenario would result in a dose to a mximally exposed individual and to the...3.1-14 3.1.7 Grumman Corporation, Space and Electronics Division (U) 3.1-17 3.2 Ground Test Sites (U) 3.2-1 3.2.1 Nevada Test Site and Saddle Mountain
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The Association for Educational Communications and Technology: Division of School Media Specialists.
ERIC Educational Resources Information Center
Miller, Mary Mock
1993-01-01
Reports on the Division of School Media Specialists of the Association for Educational Communications and Technology (AECT). Highlights include the mission statement; publications; board members and committee chairs; activities at the AECT conferences; and future concerns, including public relations and marketing plans for media specialists and…
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... always had a passion for quick fixes. Photo: History of Medicine Division, National Library of Medicine But as the ... best ways to assure a healthy weight. Photo: History of Medicine Division, National Library of Medicine To Find Out ...
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FtsZ ring: the eubacterial division apparatus conserved in archaebacteria.
Wang, X; Lutkenhaus, J
1996-07-01
FtsZ is a tubulin-like protein that is essential for cell division in eubacteria. It functions by forming a ring at the division site that directs septation. The archaebacteria constitute a kingdom of life separate from eubacteria and eukaryotes. Like eubacteria, archaebacteria are prokaryotes, although they are phylogenetically closer to eukaryotes. Here it is shown that archaebacteria also possess FtsZ and that it is biochemically similar to eubacterial FtsZs. Significantly, FtsZ from the archaebacterium Haloferax volcanii is a GTPase that is localized to a ring that coincides with the division constriction. These results indicate that the FtsZ ring was part of the division apparatus of a common prokaryotic ancestor that was retained by both eubacteria and archaebacteria.
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Skinfold thickness at 8 common cryotherapy sites in various athletic populations.
Jutte, Lisa S; Hawkins, Jeremy; Miller, Kevin C; Long, Blaine C; Knight, Kenneth L
2012-01-01
Researchers have observed slower cooling rates in thigh muscle with greater overlying adipose tissue, suggesting that cryotherapy duration should be based on the adipose thickness of the treatment site. Skinfold data do not exist for other common cryotherapy sites, and no one has reported how those skinfolds might vary because of physical activity level or sex. To determine the variability in skinfold thickness among common cryotherapy sites relative to sex and activity level (National Collegiate Athletic Association Division I athletes, recreationally active college athletes). Descriptive laboratory study. Field. Three hundred eighty-nine college students participated; 196 Division I athletes (157 men, 39 women) were recruited during preseason physicals, and 193 recreationally active college athletes (108 men, 85 women) were recruited from physical education classes. Three skinfold measurements to within 1 mm were taken at 8 sites (inferior angle of the scapula, middle deltoid, ulnar groove, midforearm, midthigh, medial collateral ligament, midcalf, and anterior talofibular ligament [ATF]) using Lange skinfold calipers. Skinfold thickness in millimeters. We noted interactions among sex, activity level, and skinfold site. Male athletes had smaller skinfold measurements than female athletes at all sites except the ATF, scapula, and ulnar groove (F₇,₂₇₀₂ = 69.85, P < .001). Skinfold measurements were greater for recreationally active athletes than their Division I counterparts at all sites except the ATF, deltoid, and ulnar groove (F₇,₂₇₀₂ = 30.79, P < .001). Thigh skinfold measurements of recreationally active female athletes were the largest, and their ATF skinfolds were the smallest. Skinfold thickness at common cryotherapy treatment sites varied based on level of physical activity and sex. Therefore, clinicians should measure skinfold thickness to determine an appropriate cryotherapy duration.
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Skinfold Thickness at 8 Common Cryotherapy Sites in Various Athletic Populations
Jutte, Lisa S.; Hawkins, Jeremy; Miller, Kevin C.; Long, Blaine C.; Knight, Kenneth L.
2012-01-01
Context: Researchers have observed slower cooling rates in thigh muscle with greater overlying adipose tissue, suggesting that cryotherapy duration should be based on the adipose thickness of the treatment site. Skinfold data do not exist for other common cryotherapy sites, and no one has reported how those skinfolds might vary because of physical activity level or sex. Objective: To determine the variability in skinfold thickness among common cryotherapy sites relative to sex and activity level (National Collegiate Athletic Association Division I athletes, recreationally active college athletes). Design: Descriptive laboratory study. Setting: Field. Patients or Other Participants: Three hundred eighty-nine college students participated; 196 Division I athletes (157 men, 39 women) were recruited during preseason physicals, and 193 recreationally active college athletes (108 men, 85 women) were recruited from physical education classes. Intervention(s): Three skinfold measurements to within 1 mm were taken at 8 sites (inferior angle of the scapula, middle deltoid, ulnar groove, midforearm, midthigh, medial collateral ligament, midcalf, and anterior talofibular ligament [ATF]) using Lange skinfold calipers. Main Outcome Measure(s): Skinfold thickness in millimeters. Results: We noted interactions among sex, activity level, and skinfold site. Male athletes had smaller skinfold measurements than female athletes at all sites except the ATF, scapula, and ulnar groove (F7,2702 = 69.85, P < .001). Skinfold measurements were greater for recreationally active athletes than their Division I counterparts at all sites except the ATF, deltoid, and ulnar groove (F7,2702 = 30.79, P < .001). Thigh skinfold measurements of recreationally active female athletes were the largest, and their ATF skinfolds were the smallest. Conclusions: Skinfold thickness at common cryotherapy treatment sites varied based on level of physical activity and sex. Therefore, clinicians should measure skinfold thickness to determine an appropriate cryotherapy duration. PMID:22488282
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,
1994-01-01
In 1990, the U.S. Geological Survey (USGS), in cooperation with the Idaho Department of Health and Welfare, Division of Environmental Quality, implemented a statewide water-quality monitoring program in response to Idaho's antidegradation policy as required by the Clean Water Act. The program objective is to provide water-quality managers with a coordinated statewide network to detect trends in surface-water quality. The monitoring program includes the collection and analysis of samples from 56 sites on the Bear, Clearwater, Kootenai, Pend Oreille, Salmon, Snake, and Spokane Rivers and their tributaries (fig. 1). Samples are collected every year at 5 sites (annual sites) in drainage basins where long-term water-quality management is practiced, every other year at 19 sites (biennial sites) in basins where land and water uses change slowly, and every third year at 32 sites (triennial sites) where future development may affect water quality. Each year, 25 of the 56 sites are sampled. This report discusses results of sampling at five annual sites. During water years 1990-93 (October 1, 1989, through September 30, 1993), samples were collected six times per year at the five annual sites (fig. 1). Onsite analyses were made for discharge, specific conductance, pH, temperature, dissolved oxygen, bacteria (fecal coliform and fecal streptococci), and alkalinity. Laboratory analyses were made for major ions, nutrients, trace elements, and suspended sediment. Suspended sediment, nitrate, fecal coliform, trace elements, and specific conductance were used to characterize surface-water quality. Because concentrations of all trace elements except zinc were near detection limits, only zinc is discussed.
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2014-05-21
CAPE CANAVERAL, Fla. – From left behind the reporter in the white shirt, Chirold Epp, the Autonomous Landing and Hazard Avoidance Technology, or ALHAT, project manager, Jon Olansen, Morpheus project manager, and Greg Gaddis, Morpheus/ALHAT site director, speak to members of the media near the north end of the Shuttle Landing Facility at NASA's Kennedy Space Center in Florida. Media also viewed Morpheus inside a facility near the landing facility. Project Morpheus tests NASA’s ALHAT and an engine that runs on liquid oxygen and methane, which are green propellants. These new capabilities could be used in future efforts to deliver cargo to planetary surfaces. The landing facility provides the lander with the kind of field necessary for realistic testing, complete with rocks, craters and hazards to avoid. Morpheus’ ALHAT payload allows it to navigate to clear landing sites amidst rocks, craters and other hazards during its descent. Project Morpheus is being managed under the Advanced Exploration Systems, or AES, Division in NASA’s Human Exploration and Operations Mission Directorate. The efforts in AES pioneer new approaches for rapidly developing prototype systems, demonstrating key capabilities and validating operational concepts for future human missions beyond Earth orbit. For more information on Project Morpheus, visit http://morpheuslander.jsc.nasa.gov/. Photo credit: NASA/Frankie Martin
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Military Review: Airland Battle Future
1991-02-01
iciy haronl~pizIilg coti pwe. RieInk fanc , sychoiniation,%-rIit and ham ontion i 11,11C Wil tx~t, i meeani mom d feetig hatdierent ll ila ifrn lsa...NOTES1. LTG John J Tolson Vetnam SWudOs Amnobdirv 1961-1971 (Washwng ment. Aviation brigades will continue recon- ,on. DC J of ft9. 973). 192 GEN John...22d Guards Motorized Infantry Brigade Trento Infantry Division Tobruk Garrison (Major Gen Scobie) Pavia Infantry Division 70th Infantry Division 20th
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-12
..., Manufacturing Truck and Activity Division, Jefferson North Assembly Plant, Including On-Site Leased Workers From..., Jefferson North Assembly Plant, Detroit, Michigan. The notice was published in the Federal Register on April... substantial portion of which are shipped to an affiliated plant where they are used in the assembly of...
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-07-10
..., Scanning and Mobility Division, Formerly Known as Hand Held Products, Inc., Including On-Site Leased Workers From Manpower, Skaneatelles Falls, NY; Amended Certification Regarding Eligibility To Apply for...''), 19 U.S.C. 2273, the Department of Labor issued a Certification of Eligibility to Apply for Worker...
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NASA Blueshift: Mobilizing The Astronomy-Interested Public Through New Media
NASA Astrophysics Data System (ADS)
Mitchell, Sara E.; Gibb, M.; Masetti, M.; Nelson, T.; Reddy, F.; Winter, E.
2010-01-01
Public interest in astronomy content is moving from mere consumption to full interaction. With the introduction of services such as Twitter, Facebook, and YouTube, audiences are eager to engage directly with content - and its creators - in more personal ways. Wikipedia is estimated to represent 100 million hours of accumulated human thought, time spent on research, discussion, and collection of information and ideas. Sites are utilizing this "social surplus" and engaging audiences to spend their free time immersed in collaboration and communication. In 2007, the Astrophysics Science Division at NASA Goddard Space Flight Center began Blueshift, a podcasting effort to provide listeners with a "backstage pass" to what's happening within the division. After focus group reviews, this effort was re-launched as part of a larger new media effort to share how and why we do science. Each episode is a cornerstone for various means of engagement, including supporting content in blogs and Twitter. We seek to engage listeners as contributors and collaborators, sharing ideas and steering the focus of future content. As we seek to build upon the interest generated during the International Year of Astronomy, we are interested in experimenting with these new forms of interaction and assessing their impacts.
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NASA Astrophysics Data System (ADS)
Shih, Yu-Ling; Le, Trung; Rothfield, Lawrence
2003-06-01
The MinCDE proteins of Escherichia coli are required for proper placement of the division septum at midcell. The site selection process requires the rapid oscillatory redistribution of the proteins from pole to pole. We report that the three Min proteins are organized into extended membrane-associated coiled structures that wind around the cell between the two poles. The pole-to-pole oscillation of the proteins reflects oscillatory changes in their distribution within the coiled structure. We also report that the E. coli MreB protein, which is required for maintaining the rod shape of the cell, also forms extended coiled structures, which are similar to the MreB structures that have previously been reported in Bacillus subtilis. The MreB and MinCDE coiled arrays do not appear identical. The results suggest that at least two functionally distinct cytoskeletal-like elements are present in E. coli and that structures of this type can undergo dynamic changes that play important roles in division site placement and possibly other aspects of the life of the cell.
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Confchem: Ensuring the Future through Education
ERIC Educational Resources Information Center
Jones, Loretta L.
2007-01-01
An online conference sponsored by the Executive Committee of the ACS Division of Chemical Education (DivCHED) was held on October 13-30, 2006. The conference is one of the CONFCHEM (CONFerences on CHEMistry) offerings of the Division's Committee on Computers in Chemical Education. Robert Belford (University of Arkansas at Little Rock) served as…
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ERIC Educational Resources Information Center
Fagan, Thomas K.; Gorin, Susan; Tharinger, Deborah
2000-01-01
Since 1969, the National Association of School Psychologists (NASP) and the Division of School Psychology within the American Psychological Association have dually influenced many psychological and educational issues in school psychology. Following a summary of the organizational topography of school psychology, the status and future directions…
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17 CFR 200.30-3 - Delegation of authority to Director of Division of Trading and Markets.
Code of Federal Regulations, 2012 CFR
2012-04-01
... orders regarding, proposals for designation of a contract market for futures trading on an index or group... significant public interest that public comment should be obtained, in which case the Division will notify... on behalf of the Commission pursuant to the Uniting and Strengthening America by Providing...
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Activities of the Structures Division, Lewis Research Center
NASA Technical Reports Server (NTRS)
1990-01-01
The purpose of the NASA Lewis Research Center, Structures Division's 1990 Annual Report is to give a brief, but comprehensive, review of the technical accomplishments of the Division during the past calendar year. The report is organized topically to match the Center's Strategic Plan. Over the years, the Structures Division has developed the technology base necessary for improving the future of aeronautical and space propulsion systems. In the future, propulsion systems will need to be lighter, to operate at higher temperatures and to be more reliable in order to achieve higher performance. Achieving these goals is complex and challenging. Our approach has been to work cooperatively with both industry and universities to develop the technology necessary for state-of-the-art advancement in aeronautical and space propulsion systems. The Structures Division consists of four branches: Structural Mechanics, Fatigue and Fracture, Structural Dynamics, and Structural Integrity. This publication describes the work of the four branches by three topic areas of Research: (1) Basic Discipline; (2) Aeropropulsion; and (3) Space Propulsion. Each topic area is further divided into the following: (1) Materials; (2) Structural Mechanics; (3) Life Prediction; (4) Instruments, Controls, and Testing Techniques; and (5) Mechanisms. The publication covers 78 separate topics with a bibliography containing 159 citations. We hope you will find the publication interesting as well as useful.
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Glynn, Jonathan M; Froehlich, John E; Osteryoung, Katherine W
2008-09-01
Chloroplasts arose from a free-living cyanobacterial endosymbiont and divide by binary fission. Division involves the assembly and constriction of the endosymbiont-derived, tubulin-like FtsZ ring on the stromal surface of the inner envelope membrane and the host-derived, dynamin-like ARC5 ring on the cytosolic surface of the outer envelope membrane. Despite the identification of many proteins required for plastid division, the factors coordinating the internal and external division machineries are unknown. Here, we provide evidence that this coordination is mediated in Arabidopsis thaliana by an interaction between ARC6, an FtsZ assembly factor spanning the inner envelope membrane, and PDV2, an ARC5 recruitment factor spanning the outer envelope membrane. ARC6 and PDV2 interact via their C-terminal domains in the intermembrane space, consistent with their in vivo topologies. ARC6 acts upstream of PDV2 to localize PDV2 (and hence ARC5) to the division site. We present a model whereby ARC6 relays information on stromal FtsZ ring positioning through PDV2 to the chloroplast surface to specify the site of ARC5 recruitment. Because orthologs of ARC6 occur in land plants, green algae, and cyanobacteria but PDV2 occurs only in land plants, the connection between ARC6 and PDV2 represents the evolution of a plant-specific adaptation to coordinate the assembly and activity of the endosymbiont- and host-derived plastid division components.
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The case of the downsizing decision.
Train, A S
1991-01-01
New CEO Charles Rampart's decision to make deep across-the-board cuts at Universal Products Company, Ltd. presents division manager Andrew Jordan with a thorny problem. Plagued by slow growth, a declining stock price, and an increasingly skeptical investment community, UPC needs to control costs and control them fast. But Jordan's division is the most profitable in the company, and the 11% cut proposed by Rampart could destroy already shaky morale and seriously threaten the division's ability to compete. "There comes a time in every manager's career when he has to fight a bad decision made by his boss," argues Sam Godwyn, Jordan's vice president for marketing and sales. "To cut across the board is to take a blunt axe to the company when a surgeon's scalpel is called for." He suggests it is better to line up support for an alternative plan that links cuts to a long-term strategy and that differentiates between successful and unsuccessful divisions. "It would be a terrible mistake for us to focus only on the narrow needs of the division when the future of the whole company is at stake," counters Mary Wyatt, Jordan's vice president for finance. Yes, the downsizing will hurt the division in the short term, but the real issue is getting behind the new CEO. Supporting the downsizing decision is a necessary investment in this future credibility and effectiveness--whatever the short-term costs. Four commentators debate Jordan's dilemma and how he should resolve it.
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Fiber optics for the future - wavelength division multiplexing
NASA Technical Reports Server (NTRS)
Spencer, J. L.
1982-01-01
Optical wavelength division multiplexing (WDM) systems, with signals transmitted on different wavelengths through a single fiber, can have increased information capacity and fault isolation properties over single wavelength optical systems. This paper describes a typical WDM system. The applicability of future standards to such a system are discussed. Also, a state-of-the-art survey of optical multimode components which could be used to implement the system are made. The components to be surveyed are sources, multiplexers, and detectors. Emphasis is given to the demultiplexer techniques which are the major developmental components in the WDM system.
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Space division multiplexing chip-to-chip quantum key distribution.
Bacco, Davide; Ding, Yunhong; Dalgaard, Kjeld; Rottwitt, Karsten; Oxenløwe, Leif Katsuo
2017-09-29
Quantum cryptography is set to become a key technology for future secure communications. However, to get maximum benefit in communication networks, transmission links will need to be shared among several quantum keys for several independent users. Such links will enable switching in quantum network nodes of the quantum keys to their respective destinations. In this paper we present an experimental demonstration of a photonic integrated silicon chip quantum key distribution protocols based on space division multiplexing (SDM), through multicore fiber technology. Parallel and independent quantum keys are obtained, which are useful in crypto-systems and future quantum network.
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NASA's Ultraviolet Astrophysics Branch: Present and future detector program
NASA Technical Reports Server (NTRS)
Welsh, Barry Y.
1992-01-01
The various concepts in ultraviolet detector technology currently being funded by NASA's Astrophysics Division to carry out observations in the 100 to 3000 A region are reviewed. In order to match the science objectives of future space missions with new observational techniques, critical detector technology needs in the ultraviolet regime have been identified. The attempt by NASA's Astrophysics Division Advanced Programs Branch to formulate an integrated detector technology plan as part of the ongoing 'Astrotech 21' program in order to provide the technology base for these astrophysics missions of the 21st century is described.
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An Evaluation Instrument for Internet Web Sites.
ERIC Educational Resources Information Center
Livengood, Stephanie Plank
This paper describes the creation of a comprehensive evaluation tool for reference librarians in adult service divisions to use in selecting World Wide Web sites as reference sources. Traditional evaluation criteria, endorsed and applied by librarians over the years, are not sufficient for the evaluation of today's hypermedia web site environment.…
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-16
...; Commencement of Construction Requirements; AREVA Enrichment Services, Eagle Rock Enrichment Facility..., Division of Fuel Cycle Safety and Safeguards, Office of Nuclear Material Safety and Safeguards, U.S... the site. Site grading and erosion control. Excavating the site including rock blasting and removal...
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NASA Technical Reports Server (NTRS)
1990-01-01
Selected research and technology activities at Ames Research Center, including the Moffett Field site and the Dryden Flight Research Facility, are summarized. These accomplishments exemplify the Center's varied and highly productive research efforts for 1990. The activities addressed are under the directories of: (1) aerospace systems which contains aircraft technology, full-scale aerodynamics research, information sciences, aerospace human factors research, and flight systems and simulation research divisions; (2) Dryden flight research facility which contains research engineering division; (3) aerophysics which contains aerodynamics, fluid dynamics, and thermosciences divisions; and (4) space research which contains advanced life support, space projects, earth system science, life science, and space science divisions, and search for extraterrestrial intelligence and space life sciences payloads offices.
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-05-17
... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-80,278] Wells Fargo Bank, N.A. Subsidiary of Wells Fargo & Company Home Mortgage Division Including On-Site Leased Workers From Aerotek, Inc., Employee Relations Associates, Manpower, Spherion, and on Call Staffing Solutions, Costa Mesa, CA; Amended Certification Regarding...
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-11-18
... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-74,142] World Color Mt. Morris, IL LLC, Premedia Chicago Division, Currently Known as Quad/Graphics, Inc., Including On-Site Leased Workers From Creative Group and Creative Circle, Schaumburg, IL; Amended Certification Regarding Eligibility To Apply for Worker Adjustment Assistance...
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Division of Personnel and Labor Relations, Department of Administration
Skip to content State of Alaska myAlaska Departments State Employees Statewide Links Back to Top Search the Division of Personnel and Labor Relations site DOPLR State of Alaska For Employees Agency HR DOPLR Studies EEO Report SOA Employee Movement Workforce Profile Boards Personnel Board State Officer
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NOVOCS TECHNOLOGY EVALUATION REPORT
An evaluation of the MACTEC Inc., NoVOCs(TM) technology ws conducted under the SITE Program, in partnership with the Naval Facilities Engineering Command SW Division, the Navy Environmental Leadership Program, the EPA Technology Innovation Office and Clean Sites, Inc. Specificall...
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Between History and Apocalypse: Stumbling
ERIC Educational Resources Information Center
Lalu, Premesh
2016-01-01
Apartheid rested on a division of the senses as much as it did on a reductive politics of racial subjection and its accompanying violence. As an instance of the division of the senses, it produced a condition of stasis in which history and a post-apartheid future were increasingly marked by a politico-religious discourse of apocalypse, and a moral…
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AAPG forms environmental unit; Geosat moving
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1992-07-20
This paper reports that the American Association of Petroleum Geologists has established a new environmental geology division, while a geology related committee is moving from Oklahoma. AAPG set up a Division of Environmental Geosciences to provide services and information to its members working in environmental geosciences, the Bernold M. Bruno Hanson of Midland, Tex., the DEG's first president. The division will publish a newsletter in October, and plans are being set to solicit technical articles for consideration by the AAPG Bulletin and for a possible future separate DEG technical publication.
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Jutras, Brandon Lyon; Scott, Molly; Parry, Bradley; Biboy, Jacob; Gray, Joe; Vollmer, Waldemar; Jacobs-Wagner, Christine
2016-08-16
Agents that cause Lyme disease, relapsing fever, leptospirosis, and syphilis belong to the phylum Spirochaetae-a unique lineage of bacteria most known for their long, spiral morphology. Despite the relevance to human health, little is known about the most fundamental aspects of spirochete growth. Here, using quantitative microscopy to track peptidoglycan cell-wall synthesis, we found that the Lyme disease spirochete Borrelia burgdorferi displays a complex pattern of growth. B. burgdorferi elongates from discrete zones that are both spatially and temporally regulated. In addition, some peptidoglycan incorporation occurs along the cell body, with the notable exception of a large region at the poles. Newborn cells inherit a highly active zone of peptidoglycan synthesis at midcell that contributes to elongation for most of the cell cycle. Concomitant with the initiation of nucleoid separation and cell constriction, second and third zones of elongation are established at the 1/4 and 3/4 cellular positions, marking future sites of division for the subsequent generation. Positioning of elongation zones along the cell is robust to cell length variations and is relatively precise over long distances (>30 µm), suggesting that cells ‟sense" relative, as opposed to absolute, cell length to establish zones of peptidoglycan synthesis. The transition from one to three zones of peptidoglycan growth during the cell cycle is also observed in relapsing fever Borrelia. However, this mode of growth does not extend to representative species from other spirochetal genera, suggesting that this distinctive growth mode represents an evolutionary divide in the spirochete phylum.
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29 CFR 785.12 - Work performed away from the premises or job site.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 29 Labor 3 2011-07-01 2011-07-01 false Work performed away from the premises or job site. 785.12 Section 785.12 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR... premises or job site. The rule is also applicable to work performed away from the premises or the job site...
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DCEG scientists discuss researching cancer causes and training future researchers
Watch scientists in the NCI Division of Cancer Epidemiology and Genetics discuss research into the causes of cancer at the population level. Topics include genome-wide association studies, HPV genomics, Li-Fraumeni syndrome, and training future scientists.
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-12
... Facilities Management LLC; Detroit, MI; Amended Certification Regarding Eligibility To Apply for Worker... shows that workers leased from Caravan Knight Facilities Management LLC were employed on-site at the... workers leased from Caravan Knight Facilities Management LLC working on-site at the Detroit, Michigan...
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Ma, Xiaolan; Ehrhardt, David W.; Margolin, William
1996-01-01
In the current model for bacterial cell division, FtsZ protein forms a ring that marks the division plane, creating a cytoskeletal framework for the subsequent action of other proteins such as FtsA. This putative protein complex ultimately generates the division septum. Herein we report that FtsZ and FtsA proteins tagged with green fluorescent protein (GFP) colocalize to division-site ring-like structures in living bacterial cells in a visible space between the segregated nucleoids. Cells with higher levels of FtsZ–GFP or with FtsA–GFP plus excess wild-type FtsZ were inhibited for cell division and often exhibited bright fluorescent spiral tubules that spanned the length of the filamentous cells. This suggests that FtsZ may switch from a septation-competent localized ring to an unlocalized spiral under some conditions and that FtsA can bind to FtsZ in both conformations. FtsZ–GFP also formed nonproductive but localized aggregates at a higher concentration that could represent FtsZ nucleation sites. The general domain structure of FtsZ–GFP resembles that of tubulin, since the C terminus of FtsZ is not required for polymerization but may regulate polymerization state. The N-terminal portion of Rhizobium FtsZ polymerized in Escherichia coli and appeared to copolymerize with E. coli FtsZ, suggesting a degree of interspecies functional conservation. Analysis of several deletions of FtsA–GFP suggests that multiple segments of FtsA are important for its localization to the FtsZ ring. PMID:8917533
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U.S. Army Reserve 88th Readiness Division Finds Big Savings
DOE Office of Scientific and Technical Information (OSTI.GOV)
None
Fact sheet features lighting work done for the U.S. Army Reserve 88th Readiness Division, which was recognized in two 2017 Interior Lighting Campaign exemplary recognition categories. The troffer lighting upgrade projects at the two recognized sites are expected to save more than 246,000 kWh annually or roughly enough electricity to run 23 homes for a year.
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78 FR 22418 - Reassignment of Commission Staff Responsibilities and Delegations of Authority
Federal Register 2010, 2011, 2012, 2013, 2014
2013-04-16
... COMMODITY FUTURES TRADING COMMISSION 17 CFR Parts 1, 3, 5, 9, 11, 31, 40, 41, 140, 145, 170, 171... AGENCY: Commodity Futures Trading Commission. ACTION: Final rule. SUMMARY: The Commission is amending its... , Division of Clearing and Risk, Commodity Futures Trading Commission, Three Lafayette Centre, 1155 21st...
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ERIC Educational Resources Information Center
Stanton, Geoff, Ed.; Richardson, William, Ed.
1997-01-01
This document contains eight papers examining different aspects of categorization, divisions, and choice in further education (FE) that were commissioned during a study of tripartite pathways (for example, academic, vocational and applied) in education and training for 16-19 year olds in the United Kingdom. The following papers are included:…
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NASA Astrophysics Data System (ADS)
Kemper, Björn; Bauwens, Andreas; Vollmer, Angelika; Ketelhut, Steffi; Langehanenberg, Patrik; Müthing, Johannes; Karch, Helge; von Bally, Gert
2010-05-01
Digital holographic microscopy (DHM) enables quantitative multifocus phase contrast imaging for nondestructive technical inspection and live cell analysis. Time-lapse investigations on human brain microvascular endothelial cells demonstrate the use of DHM for label-free dynamic quantitative monitoring of cell division of mother cells into daughter cells. Cytokinetic DHM analysis provides future applications in toxicology and cancer research.
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Yamaguchi, Takayoshi; Iida, Ken-Ichiro; Shiota, Susumu; Nakayama, Hiroaki; Yoshida, Shin-Ichi
2015-12-01
FtsZ, a protein essential for prokaryotic cell division, forms a ring structure known as the Z-ring at the division site. FtsZ has a GTP binding site and is assembled into linear structures in a GTP-dependent manner in vitro. We assessed whether guanosine 5'-diphosphate 3'-diphosphate (ppGpp), a global regulator of gene expression in starved bacteria, affects cell division in Salmonella Paratyphi A. Elevation of intracellular ppGpp levels by using the relA expression vector induced repression of bacterial growth and incorrect FtsZ assembly. We found that FtsZ forms helical structures in the presence of ppGpp by using the GTP binding site; however, ppGpp levels required to form helical structures were at least 20-fold higher than the required GTP levels in vitro. Furthermore, once formed, helical structures did not change to the straight form even after GTP addition. Our data indicate that elevation of the ppGpp level leads to inhibition of bacterial growth and interferes with FtsZ assembly. © FEMS 2015. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.
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Division of labour in the yeast: Saccharomyces cerevisiae.
Wloch-Salamon, Dominika M; Fisher, Roberta M; Regenberg, Birgitte
2017-10-01
Division of labour between different specialized cell types is a central part of how we describe complexity in multicellular organisms. However, it is increasingly being recognized that division of labour also plays an important role in the lives of predominantly unicellular organisms. Saccharomyces cerevisiae displays several phenotypes that could be considered a division of labour, including quiescence, apoptosis and biofilm formation, but they have not been explicitly treated as such. We discuss each of these examples, using a definition of division of labour that involves phenotypic variation between cells within a population, cooperation between cells performing different tasks and maximization of the inclusive fitness of all cells involved. We then propose future research directions and possible experimental tests using S. cerevisiae as a model organism for understanding the genetic mechanisms and selective pressures that can lead to the evolution of the very first stages of a division of labour. Copyright © 2017 John Wiley & Sons, Ltd. Copyright © 2017 John Wiley & Sons, Ltd.
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Polarized Cell Division of Chlamydia trachomatis
Abdelrahman, Yasser; Ouellette, Scot P.; Belland, Robert J.; Cox, John V.
2016-01-01
Bacterial cell division predominantly occurs by a highly conserved process, termed binary fission, that requires the bacterial homologue of tubulin, FtsZ. Other mechanisms of bacterial cell division that are independent of FtsZ are rare. Although the obligate intracellular human pathogen Chlamydia trachomatis, the leading bacterial cause of sexually transmitted infections and trachoma, lacks FtsZ, it has been assumed to divide by binary fission. We show here that Chlamydia divides by a polarized cell division process similar to the budding process of a subset of the Planctomycetes that also lack FtsZ. Prior to cell division, the major outer-membrane protein of Chlamydia is restricted to one pole of the cell, and the nascent daughter cell emerges from this pole by an asymmetric expansion of the membrane. Components of the chlamydial cell division machinery accumulate at the site of polar growth prior to the initiation of asymmetric membrane expansion and inhibitors that disrupt the polarity of C. trachomatis prevent cell division. The polarized cell division of C. trachomatis is the result of the unipolar growth and FtsZ-independent fission of this coccoid organism. This mechanism of cell division has not been documented in other human bacterial pathogens suggesting the potential for developing Chlamydia-specific therapeutic treatments. PMID:27505160
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Impact of high efficiency vehicles on future fuel tax revenues in Utah.
DOT National Transportation Integrated Search
2015-05-01
The Utah Department of Transportation Research Division has analyzed the potential impact of : high-efficiency motor vehicles on future State of Utah motor fuel tax revenues used to construct and maintain the : highway network. High-efficiency motor ...
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Wasley, Jane; Mooney, Thomas J; King, Catherine K
2016-04-01
A number of fuel spills, of both recent and historic origins, have occurred on World Heritage-listed subantarctic Macquarie Island. Sites contaminated by mainly diesel fuels are undergoing remediation by the Australian Antarctic Division. The risks posed by these sites are being managed using a "weight of evidence" approach, for which this study provides a preliminary line of evidence for the ecological assessment component of this site management decision framework. This knowledge is pertinent, given the absence of environmental guidelines for fuel contaminants in subantarctic ecosystems. We provide a field-based, site-specific ecological risk assessment for soil invertebrate communities across the fuel spill sites, before the commencement of in situ remediation activities. Springtails (Collembola) were the most abundant taxa. Springtail community patterns showed only limited correlations with the level of fuel contamination at the soil surface, even when elevated levels occurred in the substratum layers. Of the environmental variables measured, community patterns were most strongly correlated with vegetation cover. We identify a suite of 6 species that contribute most to the community dynamics across these sites. A subset of these we propose as useful candidates for future development of single-species toxicity tests: Folsomotoma punctata, Cryptopygus caecus, Cryptopygus antarcticus and Parisotoma insularis. Findings from this study advance our understanding of soil invertebrate community dynamics within these contaminated sites, directly contributing to the improved management and restoration of the sites. Not only does this study provide an important line of evidence for the island's ecological risk assessment for fuel contaminants, it also enhances our understanding of the potential impact of fuels at other subantarctic islands. © 2015 SETAC.
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Environmental Assessment for Vigilant Warrior Training Site
2008-07-01
occidentalis), river birch (Betula nigra), black willow (Salix nigra), red maple (Acer rubrum) and other hardwoods. The Vigilant Warrior site is...4004 L E C Maxwell Support Division April 9, 2008 Ms. Debbie Thomas Tribal Historic Preservation Officer Alabama-Coushatta Tribe of Texas 571
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-08-03
... Services, Working On-Site at Delphi Automotive Systems, LLC, Powertrain Division, El Paso, TX; Amended..., 2011, applicable to leased workers from Kelly Services working on-site at Delphi Automotive Systems... automotive components. The notice will be published soon in the Federal Register. At the request of the State...
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-09-20
... address above, or from the Division of Migratory Bird Management's Web site at http://www.fws.gov... INFORMATION CONTACT or from our Web site at http://www.fws.gov/migratorybirds . Review of Public Comments and... http://www.regulations.gov , or from our Web site at http://www.fws.gov/migratorybirds/NewReports...
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Wind Shear radar program future plans
NASA Technical Reports Server (NTRS)
Robertson, Roy E.
1991-01-01
The status of the Windshear Radar Program at the Collins Air Transport Division of Rockwell International is given in viewgraph form. Topics covered include goals, modifications to the WXR-700 system, flight test plans, technical approaches, design considerations, system considerations, certification, and future plans.
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NASA Technical Reports Server (NTRS)
Mulhall, B. D. L.
1980-01-01
The results of the analysis of the external environment of the FBI Fingerprint Identification Division are presented. Possible trends in the future environment of the Division that may have an effect on the work load were projected to determine if future work load will lie within the capability range of the proposed new system, AIDS 3. Two working models of the environment were developed, the internal and external model, and from these scenarios the projection of possible future work load volume and mixture was developed. Possible drivers of work load change were identified and assessed for upper and lower bounds of effects. Data used for the study were derived from historical information, analysis of the current situation and from interviews with various agencies who are users of or stakeholders in the present system.
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Rare Earth Elements | Alaska Division of Geological & Geophysical Surveys
- Mineral Resources main content Rare Earth Elements Rare earth elements and the supply and demand of these deposits containing rare earth elements to meet the perceived future demand. High prices for rare earth earth element occurrences in the DGGS publications catalog. Department of Natural Resources, Division of
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ERIC Educational Resources Information Center
Brown, David R.; Bushey, Michelle
2010-01-01
Two-year colleges (2YCs) provide a significant amount of chemical education to undergraduates in the United States. By design, the charge of the 2YCs is to provide coursework at the lower-division level. Nonetheless, general chemistry courses in 2YCs can be enhanced with content to prepare future chemistry majors for upper-division education. The…
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ERIC Educational Resources Information Center
2002
The Science Communication Interest Group Division of the proceedings contains the following 7 papers: "Forecasting the Future: How Television Weathercasters' Attitudes and Beliefs about Climate Change Affect Their Cognitive Knowledge on the Science" (Kris Wilson); "The Web and E-Mail in Science Communication: Results of In-Depth…
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ERIC Educational Resources Information Center
Letawsky Shultz, Nicole
2017-01-01
The responsibilities of being a Division I student-athlete often leave little time for experiences outside of sport that are critical for their future careers. Many student-athletes have unrealistic expectations of competing in their sport after college, while others expend little effort exploring potential careers. This study examines how career…
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Novak, Klemen; de Luis, Martin; Saz, Miguel A.; Longares, Luis A.; Serrano-Notivoli, Roberto; Raventós, Josep; Čufar, Katarina; Gričar, Jožica; Di Filippo, Alfredo; Piovesan, Gianluca; Rathgeber, Cyrille B. K.; Papadopoulos, Andreas; Smith, Kevin T.
2016-01-01
Climate predictions for the Mediterranean Basin include increased temperatures, decreased precipitation, and increased frequency of extreme climatic events (ECE). These conditions are associated with decreased tree growth and increased vulnerability to pests and diseases. The anatomy of tree rings responds to these environmental conditions. Quantitatively, the width of a tree ring is largely determined by the rate and duration of cell division by the vascular cambium. In the Mediterranean climate, this division may occur throughout almost the entire year. Alternatively, cell division may cease during relatively cool and dry winters, only to resume in the same calendar year with milder temperatures and increased availability of water. Under particularly adverse conditions, no xylem may be produced in parts of the stem, resulting in a missing ring (MR). A dendrochronological network of Pinus halepensis was used to determine the relationship of MR to ECE. The network consisted of 113 sites, 1,509 trees, 2,593 cores, and 225,428 tree rings throughout the distribution range of the species. A total of 4,150 MR were identified. Binomial logistic regression analysis determined that MR frequency increased with increased cambial age. Spatial analysis indicated that the geographic areas of south-eastern Spain and northern Algeria contained the greatest frequency of MR. Dendroclimatic regression analysis indicated a non-linear relationship of MR to total monthly precipitation and mean temperature. MR are strongly associated with the combination of monthly mean temperature from previous October till current February and total precipitation from previous September till current May. They are likely to occur with total precipitation lower than 50 mm and temperatures higher than 5°C. This conclusion is global and can be applied to every site across the distribution area. Rather than simply being a complication for dendrochronology, MR formation is a fundamental response of trees to adverse environmental conditions. The demonstrated relationship of MR formation to ECE across this dendrochronological network in the Mediterranean basin shows the potential of MR analysis to reconstruct the history of past climatic extremes and to predict future forest dynamics in a changing climate. PMID:27303421
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Novak, Klemen; de Luis, Martin; Saz, Miguel A; Longares, Luis A; Serrano-Notivoli, Roberto; Raventós, Josep; Čufar, Katarina; Gričar, Jožica; Di Filippo, Alfredo; Piovesan, Gianluca; Rathgeber, Cyrille B K; Papadopoulos, Andreas; Smith, Kevin T
2016-01-01
Climate predictions for the Mediterranean Basin include increased temperatures, decreased precipitation, and increased frequency of extreme climatic events (ECE). These conditions are associated with decreased tree growth and increased vulnerability to pests and diseases. The anatomy of tree rings responds to these environmental conditions. Quantitatively, the width of a tree ring is largely determined by the rate and duration of cell division by the vascular cambium. In the Mediterranean climate, this division may occur throughout almost the entire year. Alternatively, cell division may cease during relatively cool and dry winters, only to resume in the same calendar year with milder temperatures and increased availability of water. Under particularly adverse conditions, no xylem may be produced in parts of the stem, resulting in a missing ring (MR). A dendrochronological network of Pinus halepensis was used to determine the relationship of MR to ECE. The network consisted of 113 sites, 1,509 trees, 2,593 cores, and 225,428 tree rings throughout the distribution range of the species. A total of 4,150 MR were identified. Binomial logistic regression analysis determined that MR frequency increased with increased cambial age. Spatial analysis indicated that the geographic areas of south-eastern Spain and northern Algeria contained the greatest frequency of MR. Dendroclimatic regression analysis indicated a non-linear relationship of MR to total monthly precipitation and mean temperature. MR are strongly associated with the combination of monthly mean temperature from previous October till current February and total precipitation from previous September till current May. They are likely to occur with total precipitation lower than 50 mm and temperatures higher than 5°C. This conclusion is global and can be applied to every site across the distribution area. Rather than simply being a complication for dendrochronology, MR formation is a fundamental response of trees to adverse environmental conditions. The demonstrated relationship of MR formation to ECE across this dendrochronological network in the Mediterranean basin shows the potential of MR analysis to reconstruct the history of past climatic extremes and to predict future forest dynamics in a changing climate.
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Borlaug, Gwen; Edmiston, Charles E
2018-05-01
Approximately 900 surgical site infections (SSIs) were reported to the Wisconsin Division of Public Health annually from 2013 to 2015, representing the most prevalent reported health care-associated infection in the state. Personnel at the Wisconsin Division of Public Health launched an SSI prevention initiative in May 2015 using a surgical care champion to provide surgical team peer-to-peer guidance through voluntary, nonregulatory, fee-exempt onsite visits that included presentations regarding the evidence-based surgical care bundle, tours of the OR and central processing areas, and one-on-one discussions with surgeons. The surgical care champion visited 10 facilities from August to December 2015, and at those facilities, SSIs decreased from 83 in 2015 to 47 in 2016 and the overall SSI standardized infection ratio decreased by 45% from 1.61 to 0.88 (P = .002), suggesting a statewide SSI prevention champion model can help lead to improved patient outcomes. © AORN, Inc, 2018.
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Ballu, Srilata; Itteboina, Ramesh; Sivan, Sree Kanth; Manga, Vijjulatha
2018-02-01
Filamentous temperature-sensitive protein Z (FtsZ) is a protein encoded by the FtsZ gene that assembles into a Z-ring at the future site of the septum of bacterial cell division. Structurally, FtsZ is a homolog of eukaryotic tubulin but has low sequence similarity; this makes it possible to obtain FtsZ inhibitors without affecting the eukaryotic cell division. Computational studies were performed on a series of substituted 3-arylalkoxybenzamide derivatives reported as inhibitors of FtsZ activity in Staphylococcus aureus. Quantitative structure-activity relationship models (QSAR) models generated showed good statistical reliability, which is evident from r 2 ncv and r 2 loo values. The predictive ability of these models was determined and an acceptable predictive correlation (r 2 Pred ) values were obtained. Finally, we performed molecular dynamics simulations in order to examine the stability of protein-ligand interactions. This facilitated us to compare free binding energies of cocrystal ligand and newly designed molecule B1. The good concordance between the docking results and comparative molecular field analysis (CoMFA)/comparative molecular similarity indices analysis (CoMSIA) contour maps afforded obliging clues for the rational modification of molecules to design more potent FtsZ inhibitors.
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Sethi, Kriti; Palani, Saravanan; Cortés, Juan C. G.; Sato, Mamiko; Sevugan, Mayalagu; Ramos, Mariona; Vijaykumar, Shruthi; Osumi, Masako; Naqvi, Naweed I.; Ribas, Juan Carlos; Balasubramanian, Mohan
2016-01-01
Cytokinesis in many organisms requires a plasma membrane anchored actomyosin ring, whose contraction facilitates cell division. In yeast and fungi, actomyosin ring constriction is also coordinated with division septum assembly. How the actomyosin ring interacts with the plasma membrane and the plasma membrane-localized septum synthesizing machinery remains poorly understood. In Schizosaccharomyces pombe, an attractive model organism to study cytokinesis, the β-1,3-glucan synthase Cps1p / Bgs1p, an integral membrane protein, localizes to the plasma membrane overlying the actomyosin ring and is required for primary septum synthesis. Through a high-dosage suppressor screen we identified an essential gene, sbg1+ (suppressor of beta glucan synthase 1), which suppressed the colony formation defect of Bgs1-defective cps1-191 mutant at higher temperatures. Sbg1p, an integral membrane protein, localizes to the cell ends and to the division site. Sbg1p and Bgs1p physically interact and are dependent on each other to localize to the division site. Loss of Sbg1p results in an unstable actomyosin ring that unravels and slides, leading to an inability to deposit a single contiguous division septum and an important reduction of the β-1,3-glucan proportion in the cell wall, coincident with that observed in the cps1-191 mutant. Sbg1p shows genetic and / or physical interaction with Rga7p, Imp2p, Cdc15p, and Pxl1p, proteins known to be required for actomyosin ring integrity and efficient septum synthesis. This study establishes Sbg1p as a key member of a group of proteins that link the plasma membrane, the actomyosin ring, and the division septum assembly machinery in fission yeast. PMID:27749909
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Sethi, Kriti; Palani, Saravanan; Cortés, Juan C G; Sato, Mamiko; Sevugan, Mayalagu; Ramos, Mariona; Vijaykumar, Shruthi; Osumi, Masako; Naqvi, Naweed I; Ribas, Juan Carlos; Balasubramanian, Mohan
2016-10-01
Cytokinesis in many organisms requires a plasma membrane anchored actomyosin ring, whose contraction facilitates cell division. In yeast and fungi, actomyosin ring constriction is also coordinated with division septum assembly. How the actomyosin ring interacts with the plasma membrane and the plasma membrane-localized septum synthesizing machinery remains poorly understood. In Schizosaccharomyces pombe, an attractive model organism to study cytokinesis, the β-1,3-glucan synthase Cps1p / Bgs1p, an integral membrane protein, localizes to the plasma membrane overlying the actomyosin ring and is required for primary septum synthesis. Through a high-dosage suppressor screen we identified an essential gene, sbg1+ (suppressor of beta glucan synthase 1), which suppressed the colony formation defect of Bgs1-defective cps1-191 mutant at higher temperatures. Sbg1p, an integral membrane protein, localizes to the cell ends and to the division site. Sbg1p and Bgs1p physically interact and are dependent on each other to localize to the division site. Loss of Sbg1p results in an unstable actomyosin ring that unravels and slides, leading to an inability to deposit a single contiguous division septum and an important reduction of the β-1,3-glucan proportion in the cell wall, coincident with that observed in the cps1-191 mutant. Sbg1p shows genetic and / or physical interaction with Rga7p, Imp2p, Cdc15p, and Pxl1p, proteins known to be required for actomyosin ring integrity and efficient septum synthesis. This study establishes Sbg1p as a key member of a group of proteins that link the plasma membrane, the actomyosin ring, and the division septum assembly machinery in fission yeast.
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Sharma, Pankaj; Tomar, Anil Kumar; Kundu, Bishwajit
2018-02-01
Cell division is compromised in DnaAcos mutant E. coli cells due to chromosome over-replication. In these cells, CedA acts as a regulatory protein and initiates cell division by a hitherto unknown mechanism. CedA, a double stranded DNA binding protein, interacts with various subunits of RNA polymerase complex, including rpoB. To reveal how this concert between CedA, rpoB and DNA brings about cell division in E. coli, we performed biophysical and in silico analysis and obtained mechanistic insights. Interaction between CedA and rpoB was shown by circular dichroism spectrometry and in silico docking experiments. Further, CedA and rpoB were allowed to interact individually to a selected DNA and their binding was monitored by fluorescence spectroscopy. The binding constants of these interactions as determined by BioLayer Interferometry clearly show that rpoB binds to DNA with higher affinity (K D2 =<1.0E-12M) as compared to CedA (K D2 =9.58E-09M). These findings were supported by docking analysis where 12 intermolecular H-bonds were formed in rpoB-DNA complex as compared to 4 in CedA-DNA complex. Based on our data we propose that in E. coli cells chromosome over-replication signals CedA to recruit rpoB to specific DNA site(s), which initiates transcription of cell division regulatory elements. Copyright © 2017 Elsevier B.V. All rights reserved.
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DOE Office of Scientific and Technical Information (OSTI.GOV)
Dave Madsen
This Closure Report provides the documentation for closure of the Cactus Spring Waste Trenches Corrective Action Unit (CAU) 426. The site is located on the Tonopah Test Range, approximately 225 kilometers northwest of Las Vegas, NV. CAU 426 consists of one corrective action site (CAS) which is comprised of four waste trenches. The trenches were excavated to receive solid waste generated in support of Operation Roller Coaster, primary the Double Tracks Test in 1963, and were subsequently backfilled. The Double Tracks Test involved use of live animals to assess the biological hazards associated with the nonnuclear detonation of plutonium-bearing devices.more » The Nevada Division of Environmental Protection approved Corrective Action Plan (CAP)which proposed ''capping'' methodology. The closure activities were completed in accordance with the approved CAP and consisted of constructing an engineered cover in the area of the trenches, constructing/planting a vegetative cover, installing a perimeter fence and signs, implementing restrictions on future use, and preparing a Post-Closure Monitoring Plan.« less
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Bayesian Research at the NASA Ames Research Center,Computational Sciences Division
NASA Technical Reports Server (NTRS)
Morris, Robin D.
2003-01-01
NASA Ames Research Center is one of NASA s oldest centers, having started out as part of the National Advisory Committee on Aeronautics, (NACA). The site, about 40 miles south of San Francisco, still houses many wind tunnels and other aviation related departments. In recent years, with the growing realization that space exploration is heavily dependent on computing and data analysis, its focus has turned more towards Information Technology. The Computational Sciences Division has expanded rapidly as a result. In this article, I will give a brief overview of some of the past and present projects with a Bayesian content. Much more than is described here goes on with the Division. The web pages at http://ic.arc. nasa.gov give more information on these, and the other Division projects.
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2014-05-21
CAPE CANAVERAL, Fla. – Jon Olansen, Morpheus project manager, speaks to members of the media inside a facility near the Shuttle Landing Facility at NASA's Kennedy Space Center in Florida. Behind Olansen is the Project Morpheus prototype lander. Project Morpheus tests NASA’s autonomous landing and hazard avoidance technology, or ALHAT, sensors and an engine that runs on liquid oxygen and methane, which are green propellants. These new capabilities could be used in future efforts to deliver cargo to planetary surfaces. The landing facility provides the lander with the kind of field necessary for realistic testing, complete with rocks, craters and hazards to avoid. Morpheus’ ALHAT payload allows it to navigate to clear landing sites amidst rocks, craters and other hazards during its descent. Project Morpheus is being managed under the Advanced Exploration Systems, or AES, Division in NASA’s Human Exploration and Operations Mission Directorate. The efforts in AES pioneer new approaches for rapidly developing prototype systems, demonstrating key capabilities and validating operational concepts for future human missions beyond Earth orbit. For more information on Project Morpheus, visit http://morpheuslander.jsc.nasa.gov/. Photo credit: NASA/Frankie Martin
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2014-05-21
CAPE CANAVERAL, Fla. – Jon Olansen, Morpheus project manager, speaks to members of the media inside a facility near the Shuttle Landing Facility at NASA's Kennedy Space Center in Florida. Behind Olansen is the Project Morpheus prototype lander. Project Morpheus tests NASA’s autonomous landing and hazard avoidance technology, or ALHAT, sensors and an engine that runs on liquid oxygen and methane, which are green propellants. These new capabilities could be used in future efforts to deliver cargo to planetary surfaces. The landing facility provides the lander with the kind of field necessary for realistic testing, complete with rocks, craters and hazards to avoid. Morpheus’ ALHAT payload allows it to navigate to clear landing sites amidst rocks, craters and other hazards during its descent. Project Morpheus is being managed under the Advanced Exploration Systems, or AES, Division in NASA’s Human Exploration and Operations Mission Directorate. The efforts in AES pioneer new approaches for rapidly developing prototype systems, demonstrating key capabilities and validating operational concepts for future human missions beyond Earth orbit. For more information on Project Morpheus, visit http://morpheuslander.jsc.nasa.gov/. Photo credit: NASA/Frankie Martin
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2014-05-21
CAPE CANAVERAL, Fla. – Chirold Epp, the Autonomous Landing and Hazard Avoidance Technology, or ALHAT, project manager, speaks to members of the media inside a facility near the Shuttle Landing Facility at NASA's Kennedy Space Center in Florida. Behind Epp is the Project Morpheus prototype lander. Project Morpheus tests NASA’s ALHAT sensors and an engine that runs on liquid oxygen and methane, which are green propellants. These new capabilities could be used in future efforts to deliver cargo to planetary surfaces. The landing facility provides the lander with the kind of field necessary for realistic testing, complete with rocks, craters and hazards to avoid. Morpheus’ ALHAT payload allows it to navigate to clear landing sites amidst rocks, craters and other hazards during its descent. Project Morpheus is being managed under the Advanced Exploration Systems, or AES, Division in NASA’s Human Exploration and Operations Mission Directorate. The efforts in AES pioneer new approaches for rapidly developing prototype systems, demonstrating key capabilities and validating operational concepts for future human missions beyond Earth orbit. For more information on Project Morpheus, visit http://morpheuslander.jsc.nasa.gov/. Photo credit: NASA/Frankie Martin
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The Astrophysics Science Division Annual Report 2008
NASA Technical Reports Server (NTRS)
Oegerle, William; Reddy, Francis; Tyler, Pat
2009-01-01
The Astrophysics Science Division (ASD) at Goddard Space Flight Center (GSFC) is one of the largest and most diverse astrophysical organizations in the world, with activities spanning a broad range of topics in theory, observation, and mission and technology development. Scientific research is carried out over the entire electromagnetic spectrum from gamma rays to radio wavelengths as well as particle physics and gravitational radiation. Members of ASD also provide the scientific operations for three orbiting astrophysics missions WMAP, RXTE, and Swift, as well as the Science Support Center for the Fermi Gamma-ray Space Telescope. A number of key technologies for future missions are also under development in the Division, including X-ray mirrors, and new detectors operating at gamma-ray, X-ray, ultraviolet, infrared, and radio wavelengths. This report includes the Division's activities during 2008.
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NASA Technical Reports Server (NTRS)
Zeller, Mary V.; Lei, Jih-Fen
2002-01-01
The Instrumentation and Controls Division is responsible for planning, conducting and directing basic and applied research on advanced instrumentation and controls technologies for aerospace propulsion and power applications. The Division's advanced research in harsh environment sensors, high temperature high power electronics, MEMS (microelectromechanical systems), nanotechnology, high data rate optical instrumentation, active and intelligent controls, and health monitoring and management will enable self-feeling, self-thinking, self-reconfiguring and self-healing Aerospace Propulsion Systems. These research areas address Agency challenges to deliver aerospace systems with reduced size and weight, and increased functionality and intelligence for future NASA missions in advanced aeronautics, economical space transportation, and pioneering space exploration. The Division also actively supports educational and technology transfer activities aimed at benefiting all humankind.
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Lipka, Elisabeth; Gadeyne, Astrid; Stöckle, Dorothee; Zimmermann, Steffi; De Jaeger, Geert; Ehrhardt, David W.; Kirik, Viktor; Van Damme, Daniel; Müller, Sabine
2014-01-01
The preprophase band (PPB) is a faithful but transient predictor of the division plane in somatic cell divisions. Throughout mitosis the PPBs positional information is preserved by factors that continuously mark the division plane at the cell cortex, the cortical division zone, by their distinct spatio-temporal localization patterns. However, the mechanism maintaining these identity factors at the plasma membrane after PPB disassembly remains obscure. The pair of kinesin-12 class proteins PHRAGMOPLAST ORIENTING KINESIN1 (POK1) and POK2 are key players in division plane maintenance. Here, we show that POK1 is continuously present at the cell cortex, providing a spatial reference for the site formerly occupied by the PPB. Fluorescence recovery after photobleaching analysis combined with microtubule destabilization revealed dynamic microtubule-dependent recruitment of POK1 to the PPB during prophase, while POK1 retention at the cortical division zone in the absence of cortical microtubules appeared static. POK function is strictly required to maintain the division plane identity factor TANGLED (TAN) after PPB disassembly, although POK1 and TAN recruitment to the PPB occur independently during prophase. Together, our data suggest that POKs represent fundamental early anchoring components of the cortical division zone, translating and preserving the positional information of the PPB by maintaining downstream identity markers. PMID:24972597
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-26
... electronic form, will be posted on the NRC Web site and on the Federal rulemaking Web site http://www... that they do not want publicly disclosed. Federal Rulemaking Web site: Go to http://www.regulations.gov... CONTACT: Mr. Ian C. Jung, Chief, Instrumentation, Controls and Electrical Engineering Branch 2, Division...
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External Link Policy | Division of Cancer Prevention
The following graphic notice means that you are leaving the DCP Web site: (link is external)This external link provides additional information that is consistent with the intended purpose of DCP.The National Cancer Institute (NCI) cannot attest to the accuracy of a non-federal site.Linking to a non-federal site does not constitute an endorsement by HHS or any of its employees
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The Min system in rod-shaped bacteria restricts improper assembly of the division septum. In Escherichia coli, the Min system localizes to the cell poles, but in Bacillus subtilis, it is recruited to nascent cell division sites at mid-cell to prevent aberrant septation events immediately adjacent to a constricting septum. How does the cell spatially and temporally restrict the
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LAM-1 and FAT Genes Control Development of the Leaf Blade in Nicotiana sylvestris.
McHale, NA
1993-01-01
Leaf primordia of the lam-1 mutant of Nicotiana sylvestris grow normally in length but remain bladeless throughout development. The blade initiation site is established at the normal time and position in lam-1 primordia. Anticlinal divisions proceed normally in the outer L1 and L2 layers, but the inner L3 cells fail to establish the periclinal divisions that normally generate the middle mesophyll core. The lam-1 mutation also blocks formation of blade mesophyll from distal L2 cells. This suggests that LAM-1 controls a common step in initiation of blade tissue from the L2 and L3 lineage of the primordium. Another recessive mutation (fat) was isolated in N. sylvestris that induces abnormal periclinal divisions in the mesophyll during blade initiation and expansion. This generates a blade approximately twice its normal thickness by doubling the number of mesophyll cell layers from four to approximately eight. Presumably, the fat mutation defines a negative regulator involved in repression of periclinal divisions in the blade. The lam-1 fat double mutant shows radial proliferation of mesophyll cells at the blade initiation site. This produces a highly disorganized, club-shaped blade that appears to represent an additive effect of the lam-1 and fat mutations on blade founder cells. PMID:12271096
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The final cut: cell polarity meets cytokinesis at the bud neck in S. cerevisiae.
Juanes, Maria Angeles; Piatti, Simonetta
2016-08-01
Cell division is a fundamental but complex process that gives rise to two daughter cells. It includes an ordered set of events, altogether called "the cell cycle", that culminate with cytokinesis, the final stage of mitosis leading to the physical separation of the two daughter cells. Symmetric cell division equally partitions cellular components between the two daughter cells, which are therefore identical to one another and often share the same fate. In many cases, however, cell division is asymmetrical and generates two daughter cells that differ in specific protein inheritance, cell size, or developmental potential. The budding yeast Saccharomyces cerevisiae has proven to be an excellent system to investigate the molecular mechanisms governing asymmetric cell division and cytokinesis. Budding yeast is highly polarized during the cell cycle and divides asymmetrically, producing two cells with distinct sizes and fates. Many components of the machinery establishing cell polarization during budding are relocalized to the division site (i.e., the bud neck) for cytokinesis. In this review we recapitulate how budding yeast cells undergo polarized processes at the bud neck for cell division.
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-03-14
...., Mailing Solutions Management, Global Engineering Group, Including On-Site Leased Workers From Guidant... workers and former workers of Pitney Bowes, Inc., Mailing Solutions Management Division, Engineering... reviewed the certification to clarify the subject worker group's identity. Additional information revealed...
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Airland Battle Future Division Reconnaissance, a Complex Solution to a Simple Problem,
1990-12-15
producing effects, has provided the modern commander the ability to conduct continuous operations and has, in fact, created a third battlefield dimension...and limited observation are no longer ser- ious warfighting obstacles. These improved weapon systems and their influence combined to create greater...squadron into a newly designed aviation and reconnaissance battalion.5 Conceptually, this plan would create a functional split of the division-level
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2014-12-11
CAPE CANAVERAL, Fla. – NASA Project Morpheus prototype lander is being lifted by crane during preparations for free flight test number 15 at the north end of the Shuttle Landing Facility at NASA’s Kennedy Space Center in Florida. The lander will take off from the ground over a flame trench and use its autonomous landing and hazard avoidance technology, or ALHAT sensors, to survey the hazard field to determine safe landing sites. Project Morpheus tests NASA’s ALHAT and an engine that runs on liquid oxygen and methane, which are green propellants. These new capabilities could be used in future efforts to deliver cargo to planetary surfaces. Project Morpheus is being managed under the Advanced Exploration Systems, or AES, Division in NASA’s Human Exploration and Operations Mission Directorate. For more information on Project Morpheus, visit http://morpheuslander.jsc.nasa.gov/. Photo credit: NASA/Jim Grossmann
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2014-12-10
CAPE CANAVERAL, Fla. – NASA's Project Morpheus prototype lander is being transported to the north end of the Shuttle Landing Facility for free flight test number 15 at NASA’s Kennedy Space Center in Florida. The lander will take off from the ground over a flame trench and use its autonomous landing and hazard avoidance technology, or ALHAT sensors, to survey the hazard field to determine safe landing sites. Project Morpheus tests NASA’s ALHAT and an engine that runs on liquid oxygen and methane, which are green propellants. These new capabilities could be used in future efforts to deliver cargo to planetary surfaces. Project Morpheus is being managed under the Advanced Exploration Systems, or AES, Division in NASA’s Human Exploration and Operations Mission Directorate. For more information on Project Morpheus, visit http://morpheuslander.jsc.nasa.gov/. Photo credit: NASA/Jim Grossmann
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2014-12-10
CAPE CANAVERAL, Fla. – Engineers and technicians prepare NASA's Project Morpheus prototype lander for free flight test number 15 on a launch pad at the north end of the Shuttle Landing Facility at NASA's Kennedy Space Center in Florida. The lander will take off from the ground over a flame trench and use its autonomous landing and hazard avoidance technology, or ALHAT sensors, to survey the hazard field to determine safe landing sites. Project Morpheus tests NASA’s ALHAT and an engine that runs on liquid oxygen and methane, which are green propellants. These new capabilities could be used in future efforts to deliver cargo to planetary surfaces. Project Morpheus is being managed under the Advanced Exploration Systems, or AES, Division in NASA’s Human Exploration and Operations Mission Directorate. For more information on Project Morpheus, visit http://morpheuslander.jsc.nasa.gov/. Photo credit: NASA/Jim Grossmann
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2014-12-11
CAPE CANAVERAL, Fla. – Engineers and technicians prepare NASA's Project Morpheus prototype lander for free flight test number 15 at the north end of the Shuttle Landing Facility at NASA's Kennedy Space Center in Florida. The lander will take off from the ground over a flame trench and use its autonomous landing and hazard avoidance technology, or ALHAT sensors, to survey the hazard field to determine safe landing sites. Project Morpheus tests NASA’s ALHAT and an engine that runs on liquid oxygen and methane, which are green propellants. These new capabilities could be used in future efforts to deliver cargo to planetary surfaces. Project Morpheus is being managed under the Advanced Exploration Systems, or AES, Division in NASA’s Human Exploration and Operations Mission Directorate. For more information on Project Morpheus, visit http://morpheuslander.jsc.nasa.gov/. Photo credit: NASA/Jim Grossmann
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2014-12-11
CAPE CANAVERAL, Fla. – NASA's Project Morpheus prototype lander is prepared for transport to the north end of the Shuttle Landing Facility for free flight test number 15 at NASA’s Kennedy Space Center in Florida. The lander will take off from the ground over a flame trench and use its autonomous landing and hazard avoidance technology, or ALHAT sensors, to survey the hazard field to determine safe landing sites. Project Morpheus tests NASA’s ALHAT and an engine that runs on liquid oxygen and methane, which are green propellants. These new capabilities could be used in future efforts to deliver cargo to planetary surfaces. Project Morpheus is being managed under the Advanced Exploration Systems, or AES, Division in NASA’s Human Exploration and Operations Mission Directorate. For more information on Project Morpheus, visit http://morpheuslander.jsc.nasa.gov/. Photo credit: NASA/Jim Grossmann
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2014-12-11
CAPE CANAVERAL, Fla. – Engineers and technicians prepare NASA's Project Morpheus prototype lander for free flight test number 15 at the north end of the Shuttle Landing Facility at NASA's Kennedy Space Center in Florida. The lander will take off from the ground over a flame trench and use its autonomous landing and hazard avoidance technology, or ALHAT sensors, to survey the hazard field to determine safe landing sites. Project Morpheus tests NASA’s ALHAT and an engine that runs on liquid oxygen and methane, which are green propellants. These new capabilities could be used in future efforts to deliver cargo to planetary surfaces. Project Morpheus is being managed under the Advanced Exploration Systems, or AES, Division in NASA’s Human Exploration and Operations Mission Directorate. For more information on Project Morpheus, visit http://morpheuslander.jsc.nasa.gov/. Photo credit: NASA/Jim Grossmann
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2014-12-10
CAPE CANAVERAL, Fla. – NASA Project Morpheus prototype lander and support equipment are being transported to the north end of the Shuttle Landing Facility for free flight test number 15 at NASA’s Kennedy Space Center in Florida. The lander will take off from the ground over a flame trench and use its autonomous landing and hazard avoidance technology, or ALHAT sensors, to survey the hazard field to determine safe landing sites. Project Morpheus tests NASA’s ALHAT and an engine that runs on liquid oxygen and methane, which are green propellants. These new capabilities could be used in future efforts to deliver cargo to planetary surfaces. Project Morpheus is being managed under the Advanced Exploration Systems, or AES, Division in NASA’s Human Exploration and Operations Mission Directorate. For more information on Project Morpheus, visit http://morpheuslander.jsc.nasa.gov/. Photo credit: NASA/Jim Grossmann
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-02-06
... COMMODITY FUTURES TRADING COMMISSION [OMB Control Number 3038-0007] Agency Information Collection... Trading Commission. ACTION: Extension of an Existing Collection, correction. SUMMARY: This document... Ryne Miller, Division of Market Oversight, U.S. Commodity Futures Trading Commission, 1155 21st Street...
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Technology assessment for an integrated PC-based platform for three telemedicine applications
NASA Astrophysics Data System (ADS)
Tohme, Walid G.; Hayes, Wendelin S.; Dai, Hailei L.; Komo, Darmadi; Pahira, John J.; Abernethy, Darrell R.; Rennert, Wolfgang; Kuehl, Karen S.; Hauser, Gabriel J.; Mun, Seong K.
1996-05-01
This paper investigates the design and technical efficacy of an integrated PC based platform for three different medical applications. The technical efficacy of such a telemedicine platform has not been evaluated in the literature and optimal technical requirements have not been developed. The first application, with the Department of Surgery, Division of Urology, tests the utility of a telemedicine platform including radiology images for a surgical stone disease consultation service from an off site location in West Virginia. The second application, with the Department of Internal Medicine, Division of Clinical Pharmacology, investigates the usefulness of telemedicine when used for a clinical pharmacology consultation service from an off-site location. The third application, with the Department of Pediatrics, will test telemedicine for trauma care triage service first within an off-site location in Virginia and then from there to Georgetown University Medical Center.
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NASA Astrophysics Data System (ADS)
Nordal Petersen, Martin; Nuijts, Roeland; Lange Bjørn, Lars
2014-05-01
This article presents an advanced optical model for simulation of alien wavelengths in multi-domain and multi-vendor dense wavelength-division multiplexing networks. The model aids optical network planners with a better understanding of the non-linear effects present in dense wavelength-division multiplexing systems and better utilization of alien wavelengths in future applications. The limiting physical effects for alien wavelengths are investigated in relation to power levels, channel spacing, and other factors. The simulation results are verified through experimental setup in live multi-domain dense wavelength-division multiplexing systems between two national research networks: SURFnet in Holland and NORDUnet in Denmark.
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Virtual Presence: One Step Beyond Reality
NASA Technical Reports Server (NTRS)
Budden, Nancy Ann
1997-01-01
Our primary objective was to team up a group consisting of scientists and engineers from two different NASA cultures, and simulate an interactive teleoperated robot conducting geologic field work on the Moon or Mars. The information derived from the experiment will benefit both the robotics team and the planetary exploration team in the areas of robot design and development, and mission planning and analysis. The Earth Sciences and Space and Life Sciences Division combines the past with the future contributing experience from Apollo crews exploring the lunar surface, knowledge of reduced gravity environments, the performance limits of EVA suits, and future goals for human exploration beyond low Earth orbit. The Automation, Robotics. and Simulation Division brings to the table the technical expertise of robotic systems, the future goals of highly interactive robotic capabilities, treading on the edge of technology by joining for the first time a unique combination of telepresence with virtual reality.
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-07-07
... Employees Working Off-Site in Colorado, Minnesota, Ohio, and Wisconsin, and On-Site Leased Workers From Hexaware Technologies, Inc., Plymouth, MI; Amended Certification Regarding Eligibility To Apply for Worker.... 2273, the Department of Labor issued a Certification of Eligibility to Apply for Worker Adjustment...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-01-03
... Knight Facilities Management, Warren, MI; Amended Certification Regarding Eligibility To Apply for Worker... Knight Facilities Management were employed on-site at the Warren, Michigan location of the subject firm... Knight Facilities Management working on-site at the Warren, Michigan location of GMPT Warren Transmission...
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A green infrastructure experimental site for developing and evaluating models
The Ecosystems Research Division (ERD) of the U.S. EPA’s National Exposure Research Laboratory (NERL) in Athens, GA has a 14-acre urban watershed which has become an experimental research site for green infrastructure studies. About half of the watershed is covered by pervious la...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-05-03
...) Wages Are Paid Through Journey Education Marketing (JEM), Including On-Site Lease Workers From Serenity... Serenity Staffing, Accountemps, Silicon Valley and Liaison Resources, Austin and Dallas, Texas. The notice... Journey Education Marketing (JEM), and including on-site leased workers from Serenity Staffing...
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Adolescents' Orientation Toward the Future: Sex Role Differentiation in a Sociocultural Context.
ERIC Educational Resources Information Center
Seginer, Rachel
1988-01-01
Tested the future orientation of 228 Jewish and Arab adolescents. Results supported the hypothesized instrumental-expressive division between Jewish males and females and the primacy of higher education for Arab females; these gender differences are sustained by the developmental settings of Jewish and Arab adolescents. (Author/BJV)
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77 FR 68854 - Highland Associates, Inc. and Financial Investors Trust; Notice of Application
Federal Register 2010, 2011, 2012, 2013, 2014
2012-11-16
... Chief, at (202) 551-6821 (Division of Investment Management, Office of Investment Company Regulation... management investment company or series thereof that: (a) Is advised by the Adviser or any entity controlling... agreements to provide investment management services to future Funds (``Future Advisory Agreements''). The...
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Physical Property Measurements on Samples from an Analogue Soviet Nuclear Test Site: Northern Maine
1991-04-11
A Division of Maxwell Laboratory Berkeley, CA 94720 P.O. Box 1620 La Jolla, CA 92038-1620 Dr. Richard LaCoss Prof. William Menke MIT-Lincoln...90089-0741 Tucson, AZ 85721 Prof. Christopher H. Scholz Dr. William Wortman Lamont-Doherty Geological Observatory Mission Research Corporation of...Stanford, CA 94305 Reston, VA 22091 Mr. William J. Best Prof. Robert W. Clayton 907 Westwood Drive Seismological Laboratory Vienna, VA 22180 Division
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NASA Technical Reports Server (NTRS)
Hilbert, Kent; Anderson, Daniel; Lewis, David
2007-01-01
Data collected via the International GPM Program could be used to provide a solution for the NOAA Estuarine Reserves Division s System-wide Monitoring Program by augmenting in situ rainfall measurements with data acquired via future satellite-acquired precipitation data. This Candidate Solution is in alignment with the Coastal Management National Application and will benefit society by assisting in estuary preservation.
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Knutson, Stacy T.; Westwood, Brian M.; Leuthaeuser, Janelle B.; Turner, Brandon E.; Nguyendac, Don; Shea, Gabrielle; Kumar, Kiran; Hayden, Julia D.; Harper, Angela F.; Brown, Shoshana D.; Morris, John H.; Ferrin, Thomas E.; Babbitt, Patricia C.
2017-01-01
Abstract Protein function identification remains a significant problem. Solving this problem at the molecular functional level would allow mechanistic determinant identification—amino acids that distinguish details between functional families within a superfamily. Active site profiling was developed to identify mechanistic determinants. DASP and DASP2 were developed as tools to search sequence databases using active site profiling. Here, TuLIP (Two‐Level Iterative clustering Process) is introduced as an iterative, divisive clustering process that utilizes active site profiling to separate structurally characterized superfamily members into functionally relevant clusters. Underlying TuLIP is the observation that functionally relevant families (curated by Structure‐Function Linkage Database, SFLD) self‐identify in DASP2 searches; clusters containing multiple functional families do not. Each TuLIP iteration produces candidate clusters, each evaluated to determine if it self‐identifies using DASP2. If so, it is deemed a functionally relevant group. Divisive clustering continues until each structure is either a functionally relevant group member or a singlet. TuLIP is validated on enolase and glutathione transferase structures, superfamilies well‐curated by SFLD. Correlation is strong; small numbers of structures prevent statistically significant analysis. TuLIP‐identified enolase clusters are used in DASP2 GenBank searches to identify sequences sharing functional site features. Analysis shows a true positive rate of 96%, false negative rate of 4%, and maximum false positive rate of 4%. F‐measure and performance analysis on the enolase search results and comparison to GEMMA and SCI‐PHY demonstrate that TuLIP avoids the over‐division problem of these methods. Mechanistic determinants for enolase families are evaluated and shown to correlate well with literature results. PMID:28054422
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Knutson, Stacy T; Westwood, Brian M; Leuthaeuser, Janelle B; Turner, Brandon E; Nguyendac, Don; Shea, Gabrielle; Kumar, Kiran; Hayden, Julia D; Harper, Angela F; Brown, Shoshana D; Morris, John H; Ferrin, Thomas E; Babbitt, Patricia C; Fetrow, Jacquelyn S
2017-04-01
Protein function identification remains a significant problem. Solving this problem at the molecular functional level would allow mechanistic determinant identification-amino acids that distinguish details between functional families within a superfamily. Active site profiling was developed to identify mechanistic determinants. DASP and DASP2 were developed as tools to search sequence databases using active site profiling. Here, TuLIP (Two-Level Iterative clustering Process) is introduced as an iterative, divisive clustering process that utilizes active site profiling to separate structurally characterized superfamily members into functionally relevant clusters. Underlying TuLIP is the observation that functionally relevant families (curated by Structure-Function Linkage Database, SFLD) self-identify in DASP2 searches; clusters containing multiple functional families do not. Each TuLIP iteration produces candidate clusters, each evaluated to determine if it self-identifies using DASP2. If so, it is deemed a functionally relevant group. Divisive clustering continues until each structure is either a functionally relevant group member or a singlet. TuLIP is validated on enolase and glutathione transferase structures, superfamilies well-curated by SFLD. Correlation is strong; small numbers of structures prevent statistically significant analysis. TuLIP-identified enolase clusters are used in DASP2 GenBank searches to identify sequences sharing functional site features. Analysis shows a true positive rate of 96%, false negative rate of 4%, and maximum false positive rate of 4%. F-measure and performance analysis on the enolase search results and comparison to GEMMA and SCI-PHY demonstrate that TuLIP avoids the over-division problem of these methods. Mechanistic determinants for enolase families are evaluated and shown to correlate well with literature results. © 2017 The Authors Protein Science published by Wiley Periodicals, Inc. on behalf of The Protein Society.
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Does the primary site of colorectal cancer impact outcomes for patients with metastatic disease?
Price, Timothy J; Beeke, Carol; Ullah, Shahid; Padbury, Robert; Maddern, Guy; Roder, David; Townsend, Amanda R; Moore, James; Roy, Amitesh; Tomita, Yoko; Karapetis, Christos
2015-03-15
Previous reports have described differences in biology and outcome for colorectal cancer based on whether the primary is right or left sided. Further division by right, left, and rectum or even exact primary site has also been explored. Possible differences in response to biological agents have also been reported based on side of primary lesion. We explored the South Australian registry for metastatic colorectal cancer to assess if there were any differences in patient characteristics, prognostic markers, and treatment received and outcomes based on whether the primary was right or left sided. We also explored if differences exist based on left colon and rectum and by exact primary site. Two thousand nine hundred seventy-two patients were analyzed. Thirty-five percent had a right-sided primary. The median overall survival for the entire group right versus left was 9.6 versus 20.3 months (P < .001). Multivariate analysis confirmed side of primary as an independent prognostic factor. For the group that had active therapy, defined as chemotherapy (± metastasis resection), median overall survival was right, 18.2 months; and left, 29.4 months (P < .001). Importantly, we found no suggestion of major differences if left side was divided by left colon and rectum, and trends by individual site still supported a left and right division. Patients with a right-sided primary have more negative prognostic factors and indeed have inferior outcomes compared with those with a left-sided primary. Our data with further breakdown by exact site still favor a simple left-versus-right division moving forward for metastatic colorectal cancer. © 2014 American Cancer Society.
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DOE Office of Scientific and Technical Information (OSTI.GOV)
Wientjes, F.B.; Nanninga, N.
1989-06-01
The rate at which the peptidoglycan of Escherichia coli is synthesized during the division cycle was studied with two methods. One method involved synchronization of E. coli MC4100 lysA cultures by centrifugal elutriation and subsequent pulse-labeling of the synchronously growing cultures with (meso-{sup 3}H)diaminopimelic acid (({sup 3}H)Dap). The second method was autoradiography of cells pulse-labeled with ({sup 3}H)Dap. It was found that the peptidoglycan is synthesized at a more or less exponentially increasing rate during the division cycle with a slight acceleration in this rate as the cells start to constrict. Apparently, polar cap formation requires synthesis of extra surfacemore » components, presumably to accommodate for a change in the surface-to-volume ratio. Furthermore, it was found that the pool size of Dap was constant during the division cycle. Close analysis of the topography of ({sup 3}H)Dap incorporation at the constriction site revealed that constriction proceeded by synthesis of peptidoglycan at the leading edge of the invaginating cell envelope. During constriction, no reallocation of incorporation occurred, i.e., the incorporation at the leading edge remained high throughout the process of constriction. Impairment of penicillin-binding protein 3 by mutation or by the specific {beta}-lactam antibiotic furazlocillin did not affect ({sup 3}H)Dap incorporation during initiation of constriction. However, the incorporation at the constriction site was inhibited in later stages of the constriction process. It is concluded that during division at least two peptidoglycan-synthesizing systems are operating sequentially.« less
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Durand, Adeline; Desfontaines, Jean-Michel; Iurchenko, Ielyzaveta; Auger, Hélène; Leach, David R. F.
2017-01-01
Marker frequency analysis of the Escherichia coli recB mutant chromosome has revealed a deficit of DNA in a specific zone of the terminus, centred on the dif/TerC region. Using fluorescence microscopy of a marked chromosomal site, we show that the dif region is lost after replication completion, at the time of cell division, in one daughter cell only, and that the phenomenon is transmitted to progeny. Analysis by marker frequency and microscopy shows that the position of DNA loss is not defined by the replication fork merging point since it still occurs in the dif/TerC region when the replication fork trap is displaced in strains harbouring ectopic Ter sites. Terminus DNA loss in the recB mutant is also independent of dimer resolution by XerCD at dif and of Topo IV action close to dif. It occurs in the terminus region, at the point of inversion of the GC skew, which is also the point of convergence of specific sequence motifs like KOPS and Chi sites, regardless of whether the convergence of GC skew is at dif (wild-type) or a newly created sequence. In the absence of FtsK-driven DNA translocation, terminus DNA loss is less precisely targeted to the KOPS convergence sequence, but occurs at a similar frequency and follows the same pattern as in FtsK+ cells. Importantly, using ftsIts, ftsAts division mutants and cephalexin treated cells, we show that DNA loss of the dif region in the recB mutant is decreased by the inactivation of cell division. We propose that it results from septum-induced chromosome breakage, and largely contributes to the low viability of the recB mutant. PMID:28968392
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Wang, Peng; Zhang, Jie; Su, Jianbin; Wang, Peng; Liu, Jun; Liu, Bing; Feng, Dongru; Wang, Jinfa; Wang, Hongbin
2013-01-01
The nongreen plastids, such as etioplasts, chromoplasts, etc., as well as chloroplasts, are all derived from proplastids in the meristem. To date, the Min system members in plants have been identified as regulators of FtsZ-ring placement, which are essential for the symmetrical division of chloroplasts. However, the regulation of FtsZ-ring placement in nongreen plastids is poorly understood. In this study, we investigated the division site placement of nongreen plastids by examining the etioplasts as representative in Arabidopsis Min system mutants. Surprisingly, the shape and number of etioplasts in cotyledons of arc3, arc11 and mcd1 mutants were similar to that observed in wild-type plants, whereas arc12 and parc6 mutants exhibited enlarged etioplasts that were reduced in number. In order to examine nongreen plastids in true leaves, we silenced the ALB3 gene in these Min system mutant backgrounds to produce immature chloroplasts without the thylakoidal network using virus induced gene silencing (VIGS). Interestingly, consistent with our observations in etioplasts, enlarged and fewer nongreen plastids were only detected in leaves of parc6 (VIGS-ALB3) and arc12 (VIGS-ALB3) plants. Further, the FtsZ-ring assembled properly at the midpoint in nongreen plastids of arc3, arc11 and mcd1 (VIGS-ALB3) plants, but organized into multiple rings in parc6 (VIGS-ALB3) and presented fragmented filaments in arc12 (VIGS-ALB3) plants, suggesting that division site placement in nongreen plastids requires fewer components of the plant Min system. Taken together, these results suggest that division site placement in nongreen plastids is different from that in chloroplasts.
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Wang, Peng; Zhang, Jie; Su, Jianbin; Wang, Peng; Liu, Jun; Liu, Bing; Feng, Dongru; Wang, Jinfa; Wang, Hongbin
2013-01-01
The nongreen plastids, such as etioplasts, chromoplasts, etc., as well as chloroplasts, are all derived from proplastids in the meristem. To date, the Min system members in plants have been identified as regulators of FtsZ-ring placement, which are essential for the symmetrical division of chloroplasts. However, the regulation of FtsZ-ring placement in nongreen plastids is poorly understood. In this study, we investigated the division site placement of nongreen plastids by examining the etioplasts as representative in Arabidopsis Min system mutants. Surprisingly, the shape and number of etioplasts in cotyledons of arc3, arc11 and mcd1 mutants were similar to that observed in wild-type plants, whereas arc12 and parc6 mutants exhibited enlarged etioplasts that were reduced in number. In order to examine nongreen plastids in true leaves, we silenced the ALB3 gene in these Min system mutant backgrounds to produce immature chloroplasts without the thylakoidal network using virus induced gene silencing (VIGS). Interestingly, consistent with our observations in etioplasts, enlarged and fewer nongreen plastids were only detected in leaves of parc6 (VIGS-ALB3) and arc12 (VIGS-ALB3) plants. Further, the FtsZ-ring assembled properly at the midpoint in nongreen plastids of arc3, arc11 and mcd1 (VIGS-ALB3) plants, but organized into multiple rings in parc6 (VIGS-ALB3) and presented fragmented filaments in arc12 (VIGS-ALB3) plants, suggesting that division site placement in nongreen plastids requires fewer components of the plant Min system. Taken together, these results suggest that division site placement in nongreen plastids is different from that in chloroplasts. PMID:23936263
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Radioactive liquid wastes discharged to ground in the 200 Areas during 1976
DOE Office of Scientific and Technical Information (OSTI.GOV)
Mirabella, J.E.
An overall summary is presented giving the radioactive liquid wastes discharged to ground during 1976 and since startup (for both total and decayed depositions) within the Production and Waste Management Division control zone (200 Area plateau). Overall summaries are also presented for 200 East Area and for 200 West Area. The data contain an estimate of the radioactivity discharged to individual ponds, cribs and specific retention sites within the Production and Waste Management Division during 1976 and from startup through December 31, 1976; an estimate of the decayed activities from startup through 1976; the location and reference drawings of eachmore » disposal site; and the usage dates of each disposal site. The estimates for the radioactivity discharged and for decayed activities dicharged from startup through December 31, 1976 are based upon Item 4 of the Bibliography. The volume of liquid discharged to the ponds also includes major nonradioactive streams. The wastes discharged during 1976 to each active disposal site are detailed on a month-to-month basis, along with the monthly maximum concentration and average concentration data. An estimate of the radioactivity discharged to each active site along with the remaining decayed activities is given.« less
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Identifying Strategic Scientific Opportunities
As NCI's central scientific strategy office, CRS collaborates with the institute's divisions, offices, and centers to identify research opportunities to advance NCI's vision for the future of cancer research.
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Goddard's Astrophysics Science Division Annual Report 2011
NASA Technical Reports Server (NTRS)
Centrella, Joan; Reddy, Francis; Tyler, Pat
2012-01-01
The Astrophysics Science Division(ASD) at Goddard Space Flight Center(GSFC)is one of the largest and most diverse astrophysical organizations in the world, with activities spanning a broad range of topics in theory, observation, and mission and technology development. Scientific research is carried out over the entire electromagnetic spectrum from gamma rays to radiowavelengths as well as particle physics and gravitational radiation. Members of ASD also provide the scientific operations for three orbiting astrophysics missions WMAP, RXTE, and Swift, as well as the Science Support Center for the Fermi Gamma-ray Space Telescope. A number of key technologies for future missions are also under development in the Division, including X-ray mirrors, space-based interferometry, high contract imaging techniques to serch for exoplanets, and new detectors operating at gamma-ray, X-ray, ultraviolet, infrared, and radio wavelengths. The overriding goals of ASD are to carry out cutting-edge scientific research, and provide Project Scientist support for spaceflight missions, implement the goals of the NASA Strategic Plan, serve and suppport the astronomical community, and enable future missions by conceiving new conepts and inventing new technologies.
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The Astrophysics Science Division Annual Report 2009
NASA Technical Reports Server (NTRS)
Oegerle, William (Editor); Reddy, Francis (Editor); Tyler, Pat (Editor)
2010-01-01
The Astrophysics Science Division (ASD) at Goddard Space Flight Center (GSFC) is one of the largest and most diverse astrophysical organizations in the world, with activities spanning a broad range of topics in theory, observation, and mission and technology development. Scientific research is carried out over the entire electromagnetic spectrum - from gamma rays to radio wavelengths - as well as particle physics and gravitational radiation. Members of ASD also provide the scientific operations for three orbiting astrophysics missions - WMAP, RXTE, and Swift, as well as the Science Support Center for the Fermi Gamma-ray Space Telescope. A number of key technologies for future missions are also under development in the Division, including X-ray mirrors, space-based interferometry, high contrast imaging techniques to search for exoplanets, and new detectors operating at gamma-ray, X-ray, ultraviolet, infrared, and radio wavelengths. The overriding goals of ASD are to carry out cutting-edge scientific research, provide Project Scientist support for spaceflight missions, implement the goals of the NASA Strategic Plan, serve and support the astronomical community, and enable future missions by conceiving new concepts and inventing new technologies.
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Space radiation health program plan
NASA Technical Reports Server (NTRS)
1991-01-01
The Space Radiation Health Program intends to establish the scientific basis for the radiation protection of humans engaged in the exploration of space, with particular emphasis on the establishment of a firm knowledge base to support cancer risk assessment for future planetary exploration. This document sets forth the technical and management components involved in the implementation of the Space Radiation Health Program, which is a major part of the Life Sciences Division (LSD) effort in the Office of Space Science and Applications (OSSA) at the National Aeronautics and Space Administration (NASA). For the purpose of implementing this program, the Life Sciences Division supports scientific research into the fundamental mechanisms of radiation effects on living systems and the interaction of radiation with cells, tissues, and organs, and the development of instruments and processes for measuring radiation and its effects. The Life Sciences Division supports researchers at universities, NASA field centers, non-profit research institutes and national laboratories; establishes interagency agreements for cooperative use and development of facilities; and conducts a space-based research program using available and future spaceflight vehicles.
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Goddard's Astrophysics Science Division Annual Report 2013
NASA Technical Reports Server (NTRS)
Weaver, Kimberly A. (Editor); Reddy, Francis J. (Editor); Tyler, Patricia A. (Editor)
2014-01-01
The Astrophysics Science Division (ASD) at Goddard Space Flight Center (GSFC) is one of the largest and most diverse astrophysical organizations in the world, with activities spanning a broad range of topics in theory, observation, and mission and technology development. Scientific research is carried out over the entire electromagnetic spectrum from gamma rays to radio wavelengths as well as particle physics and gravitational radiation. Members of ASD also provide the scientific operations for two orbiting astrophysics missions Fermi Gamma-ray Space Telescope and Swift as well as the Science Support Center for Fermi. A number of key technologies for future missions are also under development in the Division, including X-ray mirrors, space-based interferometry, high contrast imaging techniques to search for exoplanets, and new detectors operating at gamma-ray, X-ray, ultraviolet, infrared, and radio wavelengths. The overriding goals of ASD are to carry out cutting-edge scientific research, provide Project Scientist support for spaceflight missions, implement the goals of the NASA Strategic Plan, serve and support the astronomical community, and enable future missions by conceiving new concepts and inventing new technologies.
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An Overview: NASA LeRC Structures Programs
NASA Technical Reports Server (NTRS)
Zaretsky, Erwin V.
1998-01-01
A workshop on National Structures Programs was held, jointly sponsored by the AIAA Structures Technical Committee, the University of Virginia's Center for Advanced Computational Technology and NASA. The Objectives of the Workshop were to: provide a forum for discussion of current Government-sponsored programs in the structures area; identify high potential research areas for future aerospace systems; and initiate suitable interaction mechanisms with the managers of structures programs. The presentations covered structures programs at NASA, DOD (AFOSR, ONR, ARO and DARPA), and DOE. This publication is the presentation of the Structures and Acoustics Division of the NASA Lewis Research Center. The Structures and Acoustics Division has its genesis dating back to 1943. It is responsible for NASA research related to rotating structures and structural hot sections of both airbreathing and rocket engines. The work of the division encompasses but is not limited to aeroelasticity, structural life prediction and reliability, fatigue and fracture, mechanical components such as bearings, gears, and seals, and aeroacoustics. These programs are discussed and the names of responsible individuals are provided for future reference.
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77 FR 52397 - Federal Property Suitable as Facilities To Assist the Homeless
Federal Register 2010, 2011, 2012, 2013, 2014
2012-08-29
...: 26305, 40132 Comments: Off-site removal only; sf. varies; use varies; fair conditions; restricted area..., 912, 913 Comments: Off-site removal only; sf varies; housing; fair to poor conditions; asbestos and...; office space; fair to poor conditions; secured area; prior approval to access property 258 7th Division...
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Federal Register 2010, 2011, 2012, 2013, 2014
2013-06-21
... supply of administrative support services (in support of production). The worker group includes on-site... components produced by the subject workers. Further, aggregate imports of articles like or directly... reconsideration, the worker supplied new information regarding a possible shift in the production of like or...
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Code of Federal Regulations, 2010 CFR
2010-10-01
... through the end of the State common snipe season. 5. You may only possess approved nontoxic shot while in... Division, we restrict hunting to designated sites, with each site limited to one party of hunters. 5. In.... We require persons hunting on the refuge for the first time to attend one of the four refuge-specific...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-01-26
... and General Physics Corporation Excluding Workers of the Global Purchasing and Supply Chain Division... plants. The company reports that workers leased from General Physics Corporation were employed on-site at..., Technical Center. The Department has determined that on-site workers from General Physics Corporation were...
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DOE Office of Scientific and Technical Information (OSTI.GOV)
Dopazo, A.; Tormo, A.; Aldea, M.
1987-04-01
The inhibition of cell division caused by induction of the SOS pathway in Escherichia coli structurally blocks septation, as deduced from two sets of results. Potential septation sites active at the time of SOS induction became inactivated, while those initiated during the following doubling time were active. Penicillin resistance increased in wild-type UV light-irradiated cells, a behavior similar to that observed in mutants in which structural blocks were introduced by inactivation of FtsA. Potential septation sites that have been structurally blocked by either the SOS division inhibitor, furazlocillin inhibition of PBP3, or inactivation of a TER pathway component, FtsA3, couldmore » be reactivated one doubling time after removal of the inhibitory agent in the presence of an active lon gene product. Reactivation of potential septation sites blocked by the presence of an inactivated FtsA3 was significantly lower when the lon protease was not active, suggesting that Lon plays a role in the removal of inactivated TER pathway products from the blocked potential septation sites.« less
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Determination of the Impregnant Concentrations on ASC Type Charcoal. A Magnetic Susceptibility Study
1987-10-01
commercial magnetic susceptometers were used on site at the Geological Division of CANMET , whose help is greatly appreciated. One of the susceptometers was a...CHARCOAL. A MAGNETIC SUSCEPTIBILITY STUDY (U) by S.H.C. Liang, B.H. Harrison and J.G. Pagotto Chemical Protection Section Protective Sciences Division ...analysis (11, 16-18), and surveys of literature reports (19-23). Some recent advances in instrumentation, such as the vibrating sample magnetometer (24
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Jacq, Maxime; Arthaud, Christopher; Manuse, Sylvie; Mercy, Chryslène; Bellard, Laure; Peters, Katharina; Gallet, Benoit; Galindo, Jennifer; Doan, Thierry; Vollmer, Waldemar; Brun, Yves V; VanNieuwenhze, Michael S; Di Guilmi, Anne Marie; Vernet, Thierry; Grangeasse, Christophe; Morlot, Cecile
2018-05-15
Bacterial division is intimately linked to synthesis and remodeling of the peptidoglycan, a cage-like polymer that surrounds the bacterial cell, providing shape and mechanical resistance. The bacterial division machinery, which is scaffolded by the cytoskeleton protein FtsZ, includes proteins with enzymatic, structural or regulatory functions. These proteins establish a complex network of transient functional and/or physical interactions which preserve cell shape and cell integrity. Cell wall hydrolases required for peptidoglycan remodeling are major contributors to this mechanism. Consistent with this, their deletion or depletion often results in morphological and/or division defects. However, the exact function of most of them remains elusive. In this work, we show that the putative lysozyme activity of the cell wall hydrolase Pmp23 is important for proper morphology and cell division in the opportunistic human pathogen Streptococcus pneumoniae. Our data indicate that active Pmp23 is required for proper localization of the Z-ring and the FtsZ-positioning protein MapZ. In addition, Pmp23 localizes to the division site and interacts directly with the essential peptidoglycan synthase PBP2x. Altogether, our data reveal a new regulatory function for peptidoglycan hydrolases.
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Yu, Yan; Zeng, Changchun; Shu, Siyun; Liu, Xuemei; Li, Chuhua
2014-01-01
Substance P is an endogenous neurokinin that is present in the central and peripheral nervous systems. The neuropeptide substance P and its high-affinity receptor neurokinin 1 receptor are known to play an important role in the central nervous system in inflammation, blood pressure, motor behavior and anxiety. The effects of substance P in the hippocampus and the marginal division of the striatum on memory remain poorly understood. Compared with the hippocampus as a control, immunofluorescence showed high expression of the substance P receptor, neurokinin 1, in the marginal division of the striatum of normal rats. Unilateral or bilateral injection of an antisense oligonucleotide against neurokinin 1 receptor mRNA in the rat hippocampus or marginal division of the striatum effectively reduced neurokinin 1 receptor expression. Independent of injection site, rats that received this antisense oligonucleotide showed obviously increased footshock times in a Y-maze test. These results indicate that the marginal division of the striatum plays a similar function in learning and memory to the hippocampus, which is a valuable addition to our mechanistic understanding of the learning and memory functions of the marginal division of the striatum. PMID:25206901
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Celebrating the Past and Transforming the Future
ERIC Educational Resources Information Center
Harvey, Carl A., II.
2016-01-01
2016 celebrates the sixty-fifth anniversary of the American Association of School Librarians (AASL) as a full-fledged division of the American Library Association (ALA). In this article, the author discusses celebrating the past and transforming the future. At the 2015 AASL National Conference the 65th Anniversary Giving Campaign was launched. The…
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17 CFR 30.10 - Petitions for exemption.
Code of Federal Regulations, 2012 CFR
2012-04-01
... requirement of this part may file a petition with the Secretary of the Commission, which petition must set... conditions: (1) No U.S. bank branch, office or division will engage in the trading of futures or options on... foreign futures and foreign option transactions; (5) The foreign person and each of its U.S. bank branches...
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17 CFR 30.10 - Petitions for exemption.
Code of Federal Regulations, 2013 CFR
2013-04-01
... requirement of this part may file a petition with the Secretary of the Commission, which petition must set... conditions: (1) No U.S. bank branch, office or division will engage in the trading of futures or options on... foreign futures and foreign option transactions; (5) The foreign person and each of its U.S. bank branches...
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17 CFR 30.10 - Petitions for exemption.
Code of Federal Regulations, 2011 CFR
2011-04-01
... requirement of this part may file a petition with the Secretary of the Commission, which petition must set... conditions: (1) No U.S. bank branch, office or division will engage in the trading of futures or options on... foreign futures and foreign option transactions; (5) The foreign person and each of its U.S. bank branches...
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17 CFR 30.10 - Petitions for exemption.
Code of Federal Regulations, 2014 CFR
2014-04-01
... requirement of this part may file a petition with the Secretary of the Commission, which petition must set... conditions: (1) No U.S. bank branch, office or division will engage in the trading of futures or options on... foreign futures and foreign option transactions; (5) The foreign person and each of its U.S. bank branches...
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The Development and Implementation of a New Medical Biology Major Including Physiology
ERIC Educational Resources Information Center
Goodman, Barbara E.; Koster, Karen L.; Swanson, David L.
2015-01-01
In response to the Howard Hughes Medical Institute/Association of American Medical Colleges Scientific Foundations for Future Physicians (SFFP) report and a concern for better preparing undergraduates for future doctoral programs in the health professions, the deans of the College of Arts and Sciences and Division of Basic Biomedical Sciences of…
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Microsoft's Tom Corddry on Multimedia, the Information Superhighway and the Future of Online.
ERIC Educational Resources Information Center
Herther, Nancy K.
1994-01-01
Tom Corddry, Microsoft Corporation's Creative Director for the Consumer Division, is interviewed about the Microsoft Home line of products and the development of related CD-ROM and multimedia products. Reasons for Microsoft's entry into the content market and its challenges, the market's future, and the company's interest in developing online…
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Ground Water Technical Support Center (GWTSC) Annual ...
The Ground Water Technical Support Center (GWTSC) is part of the Ground Water and Ecosystems Restoration Division (GWERD), which is based in the Robert S. Kerr Environmental Research Center in Ada, Oklahoma. The GWERD is a research division of U.S. EPA’s National Risk Management Research Laboratory (NRMRL). The GWTSC is one of an interlinked group of specialized Technical Support Centersthat were established under the Technical Support Project (TSP). The GWTSC provides technical support on issues related to groundwater. Specifically, the GWTSC provides technical support to U.S. EPA and State regulators for issues and problems related to:1. subsurface contamination (contaminants in ground water, soils and sediments),2. cross-media transfer (movement of contaminants from the subsurface to other media such as surface water or air), and3. restoration of impacted ecosystems.The GWTSC works with Remedial Project Managers (RPMs) and other decision makers to solve specific problems at Superfund, RCRA (Resource Conservation and Recovery Act), Brownfields sites, and ecosystem restoration sites. The Ground Water Technical Support Center (GWTSC) is part of the Ground Water and Ecosystems Restoration Division (GWERD), which is based in the Robert S. Kerr Environmental Research Center in Ada, Oklahoma. The GWERD is a research division of U.S. EPA’s National Risk Management Research Laboratory (NRMRL). The GWTSC is one of an interlinked group of specialized Technical Suppo
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2005-06-01
synchronization , timing and frequency to all of the traffic terminals through the reference burst. The MRT also periodically synchronizes all of the traffic...1 2005 Command and Control Research and Technology Symposium The Future of C2 Broadband Time Division Multiple Access (TDMA) Solution...UK Army) Dale White Barry Kruse Shawn White LTC Edward Eidson Thomas Mims COL Charles Dunn III Charlie Pangle Battle Command Battle
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More tooth, Less Skull: Force Structure Changes for an Uncertain Future
2012-05-17
deployments in OIF and OEF are the archetypes for force employment and span of control, highlighting the limits of modularity and the creation of ad hoc...square miles in extent. There was a wider dispersion of formations to minimize the effect of an enemy’s tactical atomic weapons. At the same time, this...The sweeping reorganization to meet the requirements of the atomic battlefield became the Pentomic Division. The Pentomic Division, officially known
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Regulation of transcription of the cell division gene ftsA during sporulation of Bacillus subtilis.
Gholamhoseinian, A; Shen, Z; Wu, J J; Piggot, P
1992-01-01
Three distinct 5' ends of ftsA mRNA were identified by S1 mapping and by primer extension analysis. These are thought to represent three transcription start sites. The transcripts from the downstream and upstream sites were detected throughout growth. The transcript from the middle site was not detected during exponential growth but was detected within 30 min of the start of sporulation, when it was the predominant transcript. Insertion of a cat cassette in the middle promoter, ftsAp2 (p2), did not affect vegetative growth but prevented postexponential symmetrical division and spore formation. Transcription from p2 was dependent on RNA polymerase containing sigma H, and promoter p2 resembled the consensus sigma H promoter. Transcription from p2 did not require expression of the spo0A, spo0B, spo0E, spo0F, or spo0K loci. Northern (RNA) blot analysis indicated that ftsA is cotranscribed with the adjacent ftsZ gene. Multiple promoters provide a mechanism by which essential vegetative genes can be subjected to sporulation control independent of control during vegetative growth. In the case of ftsA,Z, the promoters provide a mechanism to permit septum formation in conditions of nutrient depletion that might be expected to shut down the vegetative division machinery. Images PMID:1624452
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2014-12-11
CAPE CANAVERAL, Fla. – Engineers and controllers in a mobile control room prepare for flight number 15 of NASA's Project Morpheus prototype lander at the north end of the Shuttle Landing Facility, or SLF, at NASA’s Kennedy Space Center in Florida. The lander will take off from the ground over a flame trench and use its autonomous landing and hazard avoidance technology, or ALHAT sensors, to survey the hazard field to determine safe landing sites. Project Morpheus tests NASA’s ALHAT and an engine that runs on liquid oxygen and methane, which are green propellants. These new capabilities could be used in future efforts to deliver cargo to planetary surfaces. Project Morpheus is being managed under the Advanced Exploration Systems, or AES, Division in NASA’s Human Exploration and Operations Mission Directorate. For more information on Project Morpheus, visit http://morpheuslander.jsc.nasa.gov/. Photo credit: NASA/Jim Grossmann
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2014-12-11
CAPE CANAVERAL, Fla. – Engineers and technicians prepare the launch pad for NASA's Project Morpheus prototype lander at the north end of the Shuttle Landing Facility at NASA's Kennedy Space Center in Florida. Morpheus is being prepared for free flight test number 15 at the SLF. The lander will take off from the ground over a flame trench and use its autonomous landing and hazard avoidance technology, or ALHAT sensors, to survey the hazard field to determine safe landing sites. Project Morpheus tests NASA’s ALHAT and an engine that runs on liquid oxygen and methane, which are green propellants. These new capabilities could be used in future efforts to deliver cargo to planetary surfaces. Project Morpheus is being managed under the Advanced Exploration Systems, or AES, Division in NASA’s Human Exploration and Operations Mission Directorate. For more information on Project Morpheus, visit http://morpheuslander.jsc.nasa.gov/. Photo credit: NASA/Jim Grossmann
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2014-12-10
CAPE CANAVERAL, Fla. – NASA's Project Morpheus prototype lander is being transported from a hangar at the Shuttle Landing Facility, or SLF, for free flight test number 15 at the north end of the SLF at NASA’s Kennedy Space Center in Florida. The lander will take off from the ground over a flame trench and use its autonomous landing and hazard avoidance technology, or ALHAT sensors, to survey the hazard field to determine safe landing sites. Project Morpheus tests NASA’s ALHAT and an engine that runs on liquid oxygen and methane, which are green propellants. These new capabilities could be used in future efforts to deliver cargo to planetary surfaces. Project Morpheus is being managed under the Advanced Exploration Systems, or AES, Division in NASA’s Human Exploration and Operations Mission Directorate. For more information on Project Morpheus, visit http://morpheuslander.jsc.nasa.gov/. Photo credit: NASA/Jim Grossmann
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2014-12-10
CAPE CANAVERAL, Fla. – NASA's Project Morpheus prototype lander is being lowered by crane onto a launch pad at the north end of the Shuttle Landing Facility in preparation for free flight test number 15 at NASA’s Kennedy Space Center in Florida. The lander will take off from the ground over a flame trench and use its autonomous landing and hazard avoidance technology, or ALHAT sensors, to survey the hazard field to determine safe landing sites. Project Morpheus tests NASA’s ALHAT and an engine that runs on liquid oxygen and methane, which are green propellants. These new capabilities could be used in future efforts to deliver cargo to planetary surfaces. Project Morpheus is being managed under the Advanced Exploration Systems, or AES, Division in NASA’s Human Exploration and Operations Mission Directorate. For more information on Project Morpheus, visit http://morpheuslander.jsc.nasa.gov/. Photo credit: NASA/Jim Grossmann
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2014-12-11
CAPE CANAVERAL, Fla. – Engineers and technicians prepare NASA's Project Morpheus prototype lander for free flight test number 15 on a launch pad at the north end of the Shuttle Landing Facility at NASA's Kennedy Space Center in Florida. Morpheus is being lowered by crane onto the launch pad. The lander will take off from the ground over a flame trench and use its autonomous landing and hazard avoidance technology, or ALHAT sensors, to survey the hazard field to determine safe landing sites. Project Morpheus tests NASA’s ALHAT and an engine that runs on liquid oxygen and methane, which are green propellants. These new capabilities could be used in future efforts to deliver cargo to planetary surfaces. Project Morpheus is being managed under the Advanced Exploration Systems, or AES, Division in NASA’s Human Exploration and Operations Mission Directorate. For more information on Project Morpheus, visit http://morpheuslander.jsc.nasa.gov/. Photo credit: NASA/Jim Grossmann
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NASA Astrophysics Data System (ADS)
Kim, Do-Heyoung; Yong, Kijung; Im, Yeonho; Kim, Woojae; Lee, Doh Chang
2018-01-01
The Materials Challenges in Alternative and Renewable Energy Conference (MCARE 2017) was aimed at providing a forum for closely interactive communication and collaboration between leading experts from various fields related with materials in alternative and renewable energy. MCARE 2017 was held on Jeju Island, Korea on February 20-24, 2017. At this beautiful site, about 450 participants joined the conference and 459 papers were presented. About 110 foreign participants from all over the world particpated. MCARE 2017 was hosted by the Korea Institute of Chemical Engineers (KIChE) and was organized by the Materials Division of KIChE and the American Ceramic Society. Financial support was given by Lotte Chemical, LG Hausys, Jeju Convention & Visitors Bureau, and Korea Tourism Organization, Flexible Thermoelectric Semiconductor Device Technology Center, Super Ultra Low Energy and Emission Vehicle Center, Korea Institute of Materials Science, Jeju Techno Park, Center for Future Energy Materials and Devices and Korea Institute for Rare Metals.
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Whole organism lineage tracing by combinatorial and cumulative genome editing
McKenna, Aaron; Findlay, Gregory M.; Gagnon, James A.; Horwitz, Marshall S.; Schier, Alexander F.; Shendure, Jay
2016-01-01
Multicellular systems develop from single cells through distinct lineages. However, current lineage tracing approaches scale poorly to whole, complex organisms. Here we use genome editing to progressively introduce and accumulate diverse mutations in a DNA barcode over multiple rounds of cell division. The barcode, an array of CRISPR/Cas9 target sites, marks cells and enables the elucidation of lineage relationships via the patterns of mutations shared between cells. In cell culture and zebrafish, we show that rates and patterns of editing are tunable, and that thousands of lineage-informative barcode alleles can be generated. By sampling hundreds of thousands of cells from individual zebrafish, we find that most cells in adult organs derive from relatively few embryonic progenitors. In future analyses, genome editing of synthetic target arrays for lineage tracing (GESTALT) can be used to generate large-scale maps of cell lineage in multicellular systems for normal development and disease. PMID:27229144
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Technical basis for external dosimetry at the Waste Isolation Pilot Plant (WIPP)
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bradley, E.W.; Wu, C.F.; Goff, T.E.
1993-12-31
The WIPP External Dosimetry Program, administered by Westinghouse Electric Corporation, Waste Isolation Division, for the US Department of Energy (DOE), provides external dosimetry support services for operations at the Waste Isolation Pilot Plant (WIPP) Site. These operations include the receipt, experimentation with, storage, and disposal of transuranic (TRU) wastes. This document describes the technical basis for the WIPP External Radiation Dosimetry Program. The purposes of this document are to: (1) provide assurance that the WIPP External Radiation Dosimetry Program is in compliance with all regulatory requirements, (2) provide assurance that the WIPP External Radiation Dosimetry Program is derived from amore » sound technical base, (3) serve as a technical reference for radiation protection personnel, and (4) aid in identifying and planning for future needs. The external radiation exposure fields are those that are documented in the WIPP Final Safety Analysis Report.« less
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NASA Technical Reports Server (NTRS)
2002-01-01
[figure removed for brevity, see original site] Palos Crater has been suggested as a future landing site for Mars Missions. This crater has a channel called Tinto Vallis, which enters from the south. This site was suggested as a landing site because it may contain lake deposits. Palos Crater is named in honor of the port city in Spain from which Christopher Columbus sailed on his way to the New World in August of 1492. The floor of Palos Crater appears to be layered in places providing further evidence that this site may in fact have been the location of an ancient lake.Note: this THEMIS visual image has not been radiometrically nor geometrically calibrated for this preliminary release. An empirical correction has been performed to remove instrumental effects. A linear shift has been applied in the cross-track and down-track direction to approximate spacecraft and planetary motion. Fully calibrated and geometrically projected images will be released through the Planetary Data System in accordance with Project policies at a later time.NASA's Jet Propulsion Laboratory manages the 2001 Mars Odyssey mission for NASA's Office of Space Science, Washington, D.C. The Thermal Emission Imaging System (THEMIS) was developed by Arizona State University, Tempe, in collaboration with Raytheon Santa Barbara Remote Sensing. The THEMIS investigation is led by Dr. Philip Christensen at Arizona State University. Lockheed Martin Astronautics, Denver, is the prime contractor for the Odyssey project, and developed and built the orbiter. Mission operations are conducted jointly from Lockheed Martin and from JPL, a division of the California Institute of Technology in Pasadena. -
ERIC Educational Resources Information Center
American School Board Journal, 1965
1965-01-01
Auditoriums of the future, divisible auditoriums, economic advantages of multi-service space and auditorium location are discussed. Also presented are guides for buying and selecting seating, state equipment, portable stages, and stage lighting. (RK)
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Chlamydia co-opts the rod shape-determining proteins MreB and Pbp2 for cell division.
Ouellette, Scot P; Karimova, Gouzel; Subtil, Agathe; Ladant, Daniel
2012-07-01
Chlamydiae are obligate intracellular bacterial pathogens that have extensively reduced their genome in adapting to the intracellular environment. The chlamydial genome contains only three annotated cell division genes and lacks ftsZ. How this obligate intracellular pathogen divides is uncharacterized. Chlamydiae contain two high-molecular-weight (HMW) penicillin binding proteins (Pbp) implicated in peptidoglycan synthesis, Pbp2 and Pbp3/FtsI. We show here, using HMW Pbp-specific penicillin derivatives, that both Pbp2 and Pbp3 are essential for chlamydial cell division. Ultrastructural analyses of antibiotic-treated cultures revealed distinct phenotypes: Pbp2 inhibition induced internal cell bodies within a single outer membrane whereas Pbp3 inhibition induced elongated phenotypes with little internal division. Each HMW Pbp interacts with the Chlamydia cell division protein FtsK. Chlamydiae are coccoid yet contain MreB, a rod shape-determining protein linked to Pbp2 in bacilli. Using MreB-specific antibiotics, we show that MreB is essential for chlamydial growth and division. Importantly, co-treatment with MreB-specific and Pbp-specific antibiotics resulted in the MreB-inhibited phenotype, placing MreB upstream of Pbp function in chlamydial cell division. Finally, we showed that MreB also interacts with FtsK. We propose that, in Chlamydia, MreB acts as a central co-ordinator at the division site to substitute for the lack of FtsZ in this bacterium. © 2012 Blackwell Publishing Ltd.
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Control of cell division in Streptococcus pneumoniae by the conserved Ser/Thr protein kinase StkP.
Beilharz, Katrin; Nováková, Linda; Fadda, Daniela; Branny, Pavel; Massidda, Orietta; Veening, Jan-Willem
2012-04-10
How the human pathogen Streptococcus pneumoniae coordinates cell-wall synthesis during growth and division to achieve its characteristic oval shape is poorly understood. The conserved eukaryotic-type Ser/Thr kinase of S. pneumoniae, StkP, previously was reported to phosphorylate the cell-division protein DivIVA. Consistent with a role in cell division, GFP-StkP and its cognate phosphatase, GFP-PhpP, both localize to the division site. StkP localization depends on its penicillin-binding protein and Ser/Thr-associated domains that likely sense uncross-linked peptidoglycan, because StkP and PhpP delocalize in the presence of antibiotics that target the latest stages of cell-wall biosynthesis and in cells that have stopped dividing. Time-lapse microscopy shows that StkP displays an intermediate timing of recruitment to midcell: StkP arrives shortly after FtsA but before DivIVA. Furthermore, StkP remains at midcell longer than FtsA, until division is complete. Cells mutated for stkP are perturbed in cell-wall synthesis and display elongated morphologies with multiple, often unconstricted, FtsA and DivIVA rings. The data show that StkP plays an important role in regulating cell-wall synthesis and controls correct septum progression and closure. Overall, our results indicate that StkP signals information about the cell-wall status to key cell-division proteins and in this way acts as a regulator of cell division.
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NASA Astrophysics Data System (ADS)
Nguyen, HoangViet
2015-03-01
We have investigated and demonstrated a novel scheme to generate 2.5 Gbit/s 64 QAM orthogonal frequency division multiplexing (OFDM) signals for Radio Over Fiber (ROF) systems. We employ Fiber Bragg Grating (FBG) because the repetitive frequency of the RF source and the bandwidth of the optical modulator are largely reduced and the architecture of the ROF system is simpler. Wavelength-Division-Multiplexed Passive Optical Network (WDM-PON) has been considered as a promising solution for future broadband access networks. Principle of WDM-PON access network compatible with OFDM-ROF systems is investigated. This novel scheme which has multiple double-frequency technique to generate mm-wave signal to carry OFDM signals is a practical scheme to be applied for future broadband access networks.
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Gorrepati, Lakshmi; Thompson, Kenneth W; Eisenmann, David M
2013-05-01
The C. elegans seam cells are lateral epithelial cells arrayed in a single line from anterior to posterior that divide in an asymmetric, stem cell-like manner during larval development. These asymmetric divisions are regulated by Wnt signaling; in most divisions, the posterior daughter in which the Wnt pathway is activated maintains the progenitor seam fate, while the anterior daughter in which the Wnt pathway is not activated adopts a differentiated hypodermal fate. Using mRNA tagging and microarray analysis, we identified the functionally redundant GATA factor genes egl-18 and elt-6 as Wnt pathway targets in the larval seam cells. EGL-18 and ELT-6 have previously been shown to be required for initial seam cell specification in the embryo. We show that in larval seam cell asymmetric divisions, EGL-18 is expressed strongly in the posterior seam-fated daughter. egl-18 and elt-6 are necessary for larval seam cell specification, and for hypodermal to seam cell fate transformations induced by ectopic Wnt pathway overactivation. The TCF homolog POP-1 binds a site in the egl-18 promoter in vitro, and this site is necessary for robust seam cell expression in vivo. Finally, larval overexpression of EGL-18 is sufficient to drive expression of a seam marker in other hypodermal cells in wild-type animals, and in anterior hypodermal-fated daughters in a Wnt pathway-sensitized background. These data suggest that two GATA factors that are required for seam cell specification in the embryo independently of Wnt signaling are reused downstream of Wnt signaling to maintain the progenitor fate during stem cell-like divisions in larval development.
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Gorrepati, Lakshmi; Thompson, Kenneth W.; Eisenmann, David M.
2013-01-01
The C. elegans seam cells are lateral epithelial cells arrayed in a single line from anterior to posterior that divide in an asymmetric, stem cell-like manner during larval development. These asymmetric divisions are regulated by Wnt signaling; in most divisions, the posterior daughter in which the Wnt pathway is activated maintains the progenitor seam fate, while the anterior daughter in which the Wnt pathway is not activated adopts a differentiated hypodermal fate. Using mRNA tagging and microarray analysis, we identified the functionally redundant GATA factor genes egl-18 and elt-6 as Wnt pathway targets in the larval seam cells. EGL-18 and ELT-6 have previously been shown to be required for initial seam cell specification in the embryo. We show that in larval seam cell asymmetric divisions, EGL-18 is expressed strongly in the posterior seam-fated daughter. egl-18 and elt-6 are necessary for larval seam cell specification, and for hypodermal to seam cell fate transformations induced by ectopic Wnt pathway overactivation. The TCF homolog POP-1 binds a site in the egl-18 promoter in vitro, and this site is necessary for robust seam cell expression in vivo. Finally, larval overexpression of EGL-18 is sufficient to drive expression of a seam marker in other hypodermal cells in wild-type animals, and in anterior hypodermal-fated daughters in a Wnt pathway-sensitized background. These data suggest that two GATA factors that are required for seam cell specification in the embryo independently of Wnt signaling are reused downstream of Wnt signaling to maintain the progenitor fate during stem cell-like divisions in larval development. PMID:23633508
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Programmatic Life Cycle Environmental Assessment for Smoke/Obscurants. Volume 5. Dye/Colored Smokes
1983-07-01
mostly of test or training debtls, i.e., expanded rounds and/or packaging materials or munition duds. SOP’s and test 0 plans which are required for each...This procedure I; especially applicable to test sites, If a safety (handling) hazard exists with colored smoke munitions and for excess mix, the material ...Countermeasures and Test Division Roger L. Schultz, DRCPM-SMK-M, Material Development and Technology ".• ,.Division Sq 52 I.,.’. S%" 2. Chemical Research and
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Asymmetric cellular memory in bacteria exposed to antibiotics.
Mathis, Roland; Ackermann, Martin
2017-03-09
The ability to form a cellular memory and use it for cellular decision-making could help bacteria to cope with recurrent stress conditions. We analyzed whether bacteria would form a cellular memory specifically if past events are predictive of future conditions. We worked with the asymmetrically dividing bacterium Caulobacter crescentus where past events are expected to only be informative for one of the two cells emerging from division, the sessile cell that remains in the same microenvironment and does not migrate. Time-resolved analysis of individual cells revealed that past exposure to low levels of antibiotics increases tolerance to future exposure for the sessile but not for the motile cell. Using computer simulations, we found that such an asymmetry in cellular memory could be an evolutionary response to situations where the two cells emerging from division will experience different future conditions. Our results raise the question whether bacteria can evolve the ability to form and use cellular memory conditionally in situations where it is beneficial.
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-12
... Qimonda AG Sandston, VA; Amended Certification Regarding Eligibility To Apply for Worker Adjustment..., Sandston, Virginia. The notice was published in the Federal Register on December 30, 2008 (73 FR 79914... division of Select Staffing were employed on-site at the Sandston, Virginia location of Qimonda 200MM...
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-08-23
..., C R Associates, Syncreon, Robinson Solutions and Dupont Performance Coatings Fenton, MO; Amended... produce performance coating solutions for vehicles. The company reports that workers leased from DuPont Performance Coatings, a wholly-owned subsidiary of E.I. DuPont de Nemours Company, OEM, were employed on-site...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-09-02
....m. in your local time zone, or log onto the Wage and Hour Division's Web site for a nationwide... INFORMATION: I. Electronic Access and Filing Comments Public Participation: This notice of proposed rulemaking is available through the Federal Register and the http://www.regulations.gov Web site. You may also...
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Photographic copy of original design drawing, dated January 1970, revised ...
Photographic copy of original design drawing, dated January 1970, revised 24 May 1972 (original Army Operational Drawing in the possession of U.S. Army Corps of Engineers, Huntsville, Division). MSRPP general floor plan, lower level - Stanely R. Mickelsen Safeguard Complex, Missile Site Radar Power Plant, Southeast of, & adjacent to, Missile Site Control Building, Nekoma, Cavalier County, ND
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DOE Office of Scientific and Technical Information (OSTI.GOV)
Hazen Ed., T.C.
On behalf of the Subsurface Biogeochemical Research (SBR) program managers in the Climate and Environmental Sciences Division (CESD), Office of Biological and Environmental Research (BER), welcome to the 2011 SBR Principal Investigators meeting. Thank you in advance for your attendance and your presentations at this year's meeting. As the events in Japan continue to unfold, we are all reminded that the research we perform on radionuclide behavior in the environment has implications beyond legacy waste cleanup and in fact has its place in the discussion on the expanded use of nuclear power. As in the past, there are three broadmore » objectives to the Principal Investigators meeting: (1) to provide opportunities to share research results and promote interactions among the SBR scientists and other invited guests; (2) to evaluate the progress of each project within the program; and (3) to showcase the scientific expertise and research progress over the past year to senior managers within the DOE Office of Science, the technology offices within DOE, and other invited attendees from other Federal Agencies. This past year has seen a few significant changes within BER and within the SBR program. In November, our Associate Director for BER, Anna Palmisano, retired from Federal service. Just this month, Dr. Sharlene Weatherwax (Division Director for Biological Systems Sciences) has been named as the new Associate Director for BER. In August, BER welcomed Dr. Gary Geernaert as the new Division Director for CESD. Gary joins the division from Los Alamos National Laboratory with a background in atmospheric science. Within the SBR program, a new Strategic Plan was completed last June (currently posted on the SBR and the Office of Science website). The new strategic plan is intended to foster integration within the Environmental Systems Science portion of the BER budget that includes both SBR and Terrestrial Ecosystem Sciences (TES). Both these programs share a goal of advancing a predictive understanding of environmental processes and utilizing iterative, multidisciplinary approaches to understand complex environmental systems of relevance to DOE. CESD in general is undergoing continued discussions on integration among its programs in an effort to develop a new strategic plan for the division. This effort also includes identifying opportunities for integration with BER's Biological Systems Science Division (BSSD). The program this year includes three poster presentation sessions, six plenary sessions, and three breakout sessions. The plenary session on Tuesday morning will feature introductory presentations by BER program staff and three keynote addresses from Dr. Ken Bencala (USGS), Dr. Michael (Mick) Follows (MIT) and Dr. Sue Brantley (PSU) that will lead into three breakout sessions Tuesday afternoon. The breakout sessions are intended to highlight key developments in SBR research and foster a dialog among session participants on scientific paths forward in each particular area. The SBR program managers are asking for input from the SBR community at these sessions to help guide future efforts and/or identify areas of integration within BER programs. On Wednesday, plenary sessions will continue in the morning, followed by an early afternoon poster session. After an extended break for lunch, plenary sessions will continue in the afternoon, followed by an evening poster session. Thursday's plenary session will focus on selected highlights of research efforts at the IFRC sites and on a new potential TES field effort in the Arctic. This new field site is an obvious point of integration between the SBR and TES programs.« less
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1985-01-01
concensus about futrue war because of the nature of the Army’s external and internal environment . The armored force missions which resulted from the several...at the key environmental factors, both external and internal which helped to shape the armored division in the formative years from 1926-1938. An...difficult to understand, particularly during peacetime. The army must correctly project the future nature of war. Since there is no model for this
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Does the Current 20th Century Navy Personnel Management System Meet 21st Century Sailors’ Needs
2003-04-01
symbols and our institutions. Technology moves non-human logic to center stage in our overall development. 10 Emile Durkheim in his seminal work, The...Management and Labor Economics Literature The Division of Labor in Society by Emile Durkheim explored the area of how complex societies demand a...the Future: The 1990’s and Beyond. New York: Penguin Books, 1992; Truman Talley Books/Plume, 1993. Durkheim , Emile . The Division of Labor in
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NASA earth science and applications division: The program and plans for FY 1988-1989-1990
NASA Technical Reports Server (NTRS)
1988-01-01
Described here are the Division's research goals, priorities and emphases for the next several years and an outline of longer term plans. Included are highlights of recent accomplishments, current activities in FY 1988, research emphases in FY 1989, and longer term future plans. Data and information systems, the Geodynamics Program, the Land Processes Program, the Oceanic Processes Program, the Atmospheric Dynamics and Radiation Program, the Atmospheric Chemistry Program, and space flight programs are among the topic covered.
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Flight opportunities for science teacher enrichment
NASA Technical Reports Server (NTRS)
Devore, Edna; Gillespie, Carlton, Jr.; Hull, Garth; Koch, David
1995-01-01
NASA Astrophysics Division supports a pre-college teacher program to provide Flight Opportunities for Science Teacher EnRichment (FOSTER). To date, forty-five teachers are participating, and the program will expand nation-wide to serve fifty teachers per year on board the Kuiper Airborne Observatory. In the future, the Stratospheric Observatory for Infrared Astronomy (SOFIA) will bring more than one-hundred teachers per year on board for astronomical research mission. FOSTER is supported by a grant to the SETI Institute from the NASA Astrophysics Division, NAGW-3291.
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[Funding for Division of Microbiology in 2014 by National Natural Science Foundation of China].
Qiao, Jianjun; Huang, Chenyang; Liu, Lin; Wen, Mingzhang
2015-02-04
In this paper, we provided an overview of proposals submitted and projects funded in 2014 at the Division of Microbiology, Department of Life Sciences, National Natural Science Foundation of China. The traits and problems in different sub-disciplines were analyzed, the background, results and analysis of internet voting before panel meetings in Microbiology discipline were also introduced. The information will provide references for Chinese researchers to apply funding in microbiology discipline in the future.
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1993-05-01
significant as changes which occurred a century ago with the Teddy Roosevelt-sponsored Mahanian revolution. Indeed, one critic 3 . hinks this "hurtful...crucial areas as well as jobs seem to be at play. He has endorsed development of the V-22 Osprey for the Marines and improvement in fast sealift...total) 450 340 290 Carriers 13 12 8 SSNs 80 40 40 Assault Ships 50 50 50 Marine Corps Active Divisions 21/3 2 2 Reserve Divisions 1 1 1 Sealift Fast
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NASA's Solar System Treks: Online Portals for Planetary Mapping and Modeling
NASA Technical Reports Server (NTRS)
Day, Brian
2017-01-01
NASA's Solar System Treks are a suite of web-based of lunar and planetary mapping and modeling portals providing interactive visualization and analysis tools enabling mission planners, planetary scientists, students, and the general public to access mapped lunar data products from past and current missions for the Moon, Mars, Vesta, and more. New portals for additional planetary bodies are being planned. This presentation will recap significant enhancements to these toolsets during the past year and look ahead to future features and releases. Moon Trek is a new portal replacing its predecessor, the Lunar Mapping and Modeling Portal (LMMP), that significantly upgrades and builds upon the capabilities of LMMP. It features greatly improved navigation, 3D visualization, fly-overs, performance, and reliability. Additional data products and tools continue to be added. These include both generalized products as well as polar data products specifically targeting potential sites for NASA's Resource Prospector mission as well as for missions being planned by NASA's international partners. The latest release of Mars Trek includes new tools and data products requested by NASA's Planetary Science Division to support site selection and analysis for Mars Human Landing Exploration Zone Sites. Also being given very high priority by NASA Headquarters is Mars Trek's use as a means to directly involve the public in upcoming missions, letting them explore the areas the agency is focusing upon, understand what makes these sites so fascinating, follow the selection process, and get caught up in the excitement of exploring Mars. Phobos Trek, the latest effort in the Solar System Treks suite, is being developed in coordination with the International Phobos/Deimos Landing Site Working Group, with landing site selection and analysis for JAXA's MMX (Martian Moons eXploration) mission as a primary driver.
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NASA's Solar System Treks: Online Portals for Planetary Mapping and Modeling
NASA Astrophysics Data System (ADS)
Day, B. H.; Law, E.
2017-12-01
NASA's Solar System Treks are a suite of web-based of lunar and planetary mapping and modeling portals providing interactive visualization and analysis tools enabling mission planners, planetary scientists, students, and the general public to access mapped lunar data products from past and current missions for the Moon, Mars, Vesta, and more. New portals for additional planetary bodies are being planned. This presentation will recap significant enhancements to these toolsets during the past year and look ahead to future features and releases. Moon Trek is a new portal replacing its predecessor, the Lunar Mapping and Modeling Portal (LMMP), that significantly upgrades and builds upon the capabilities of LMMP. It features greatly improved navigation, 3D visualization, fly-overs, performance, and reliability. Additional data products and tools continue to be added. These include both generalized products as well as polar data products specifically targeting potential sites for NASA's Resource Prospector mission as well as for missions being planned by NASA's international partners. The latest release of Mars Trek includes new tools and data products requested by NASA's Planetary Science Division to support site selection and analysis for Mars Human Landing Exploration Zone Sites. Also being given very high priority by NASA Headquarters is Mars Trek's use as a means to directly involve the public in upcoming missions, letting them explore the areas the agency is focusing upon, understand what makes these sites so fascinating, follow the selection process, and get caught up in the excitement of exploring Mars. Phobos Trek, the latest effort in the Solar System Treks suite, is being developed in coordination with the International Phobos/Deimos Landing Site Working Group, with landing site selection and analysis for JAXA's MMX mission as a primary driver.
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Morpheus Alhat Tether Test Preparations
2014-03-27
CAPE CANAVERAL, Fla. – Engineers and technicians prepare the Project Morpheus prototype lander for a tether test near a new launch site at the north end of the Shuttle Landing Facility at NASA's Kennedy Space Center in Florida. The launch pad was moved to a different location at the landing facility to support the next phase of flight testing. Project Morpheus tests NASA’s automated landing and hazard avoidance technology, or ALHAT, and an engine that runs on liquid oxygen and methane, or green propellants, into a fully-operational lander that could deliver cargo to other planetary surfaces. The landing facility provides the lander with the kind of field necessary for realistic testing, complete with rocks, craters and hazards to avoid. Morpheus’ ALHAT payload allows it to navigate to clear landing sites amidst rocks, craters and other hazards during its descent. Project Morpheus is being managed under the Advanced Exploration Systems, or AES, Division in NASA’s Human Exploration and Operations Mission Directorate. The efforts in AES pioneer new approaches for rapidly developing prototype systems, demonstrating key capabilities and validating operational concepts for future human missions beyond Earth orbit. For more information on Project Morpheus, visit http://morpheuslander.jsc.nasa.gov/. Photo credit: NASA/Ben Smegelsky
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Morpheus Alhat Tether Test Preparations
2014-03-27
CAPE CANAVERAL, Fla. – NASA's Project Morpheus prototype lander is positioned near a new launch site at the north end of the Shuttle Landing Facility at NASA’s Kennedy Space Center in Florida for a tether test. The launch pad was moved to a different location at the landing facility to support the next phase of flight testing. Project Morpheus tests NASA’s automated landing and hazard avoidance technology, or ALHAT, and an engine that runs on liquid oxygen and methane, or green propellants, into a fully-operational lander that could deliver cargo to other planetary surfaces. The landing facility provides the lander with the kind of field necessary for realistic testing, complete with rocks, craters and hazards to avoid. Morpheus’ ALHAT payload allows it to navigate to clear landing sites amidst rocks, craters and other hazards during its descent. Project Morpheus is being managed under the Advanced Exploration Systems, or AES, Division in NASA’s Human Exploration and Operations Mission Directorate. The efforts in AES pioneer new approaches for rapidly developing prototype systems, demonstrating key capabilities and validating operational concepts for future human missions beyond Earth orbit. For more information on Project Morpheus, visit http://morpheuslander.jsc.nasa.gov/. Photo credit: NASA/Ben Smegelsky
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Morpheus Alhat Tether Test Preparations
2014-03-27
CAPE CANAVERAL, Fla. – A technician prepares the Project Morpheus prototype lander for a tether test near a new launch site at the north end of the Shuttle Landing Facility at NASA's Kennedy Space Center in Florida. The launch pad was moved to a different location at the landing facility to support the next phase of flight testing. Project Morpheus tests NASA’s automated landing and hazard avoidance technology, or ALHAT, and an engine that runs on liquid oxygen and methane, or green propellants, into a fully-operational lander that could deliver cargo to other planetary surfaces. The landing facility provides the lander with the kind of field necessary for realistic testing, complete with rocks, craters and hazards to avoid. Morpheus’ ALHAT payload allows it to navigate to clear landing sites amidst rocks, craters and other hazards during its descent. Project Morpheus is being managed under the Advanced Exploration Systems, or AES, Division in NASA’s Human Exploration and Operations Mission Directorate. The efforts in AES pioneer new approaches for rapidly developing prototype systems, demonstrating key capabilities and validating operational concepts for future human missions beyond Earth orbit. For more information on Project Morpheus, visit http://morpheuslander.jsc.nasa.gov/. Photo credit: NASA/Ben Smegelsky
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Mass storage system experiences and future needs at the National Center for Atmospheric Research
NASA Technical Reports Server (NTRS)
Olear, Bernard T.
1992-01-01
This presentation is designed to relate some of the experiences of the Scientific Computing Division at NCAR dealing with the 'data problem'. A brief history and a development of some basic Mass Storage System (MSS) principles are given. An attempt is made to show how these principles apply to the integration of various components into NCAR's MSS. There is discussion of future MSS needs for future computing environments.
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Progress on the Fabric for Frontier Experiments Project at Fermilab
NASA Astrophysics Data System (ADS)
Box, Dennis; Boyd, Joseph; Dykstra, Dave; Garzoglio, Gabriele; Herner, Kenneth; Kirby, Michael; Kreymer, Arthur; Levshina, Tanya; Mhashilkar, Parag; Sharma, Neha
2015-12-01
The FabrIc for Frontier Experiments (FIFE) project is an ambitious, major-impact initiative within the Fermilab Scientific Computing Division designed to lead the computing model for Fermilab experiments. FIFE is a collaborative effort between experimenters and computing professionals to design and develop integrated computing models for experiments of varying needs and infrastructure. The major focus of the FIFE project is the development, deployment, and integration of Open Science Grid solutions for high throughput computing, data management, database access and collaboration within experiment. To accomplish this goal, FIFE has developed workflows that utilize Open Science Grid sites along with dedicated and commercial cloud resources. The FIFE project has made significant progress integrating into experiment computing operations several services including new job submission services, software and reference data distribution through CVMFS repositories, flexible data transfer client, and access to opportunistic resources on the Open Science Grid. The progress with current experiments and plans for expansion with additional projects will be discussed. FIFE has taken a leading role in the definition of the computing model for Fermilab experiments, aided in the design of computing for experiments beyond Fermilab, and will continue to define the future direction of high throughput computing for future physics experiments worldwide.
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2014-05-21
CAPE CANAVERAL, Fla. – From left, Chirold Epp, the Autonomous Landing and Hazard Avoidance Technology, or ALHAT, project manager, and Jon Olansen, Morpheus project manager, speak to members of the media near the north end of the Shuttle Landing Facility at NASA's Kennedy Space Center in Florida. Media also viewed Morpheus inside a facility near the landing facility. Project Morpheus tests NASA’s ALHAT and an engine that runs on liquid oxygen and methane, which are green propellants. These new capabilities could be used in future efforts to deliver cargo to planetary surfaces. The landing facility provides the lander with the kind of field necessary for realistic testing, complete with rocks, craters and hazards to avoid. Morpheus’ ALHAT payload allows it to navigate to clear landing sites amidst rocks, craters and other hazards during its descent. Project Morpheus is being managed under the Advanced Exploration Systems, or AES, Division in NASA’s Human Exploration and Operations Mission Directorate. The efforts in AES pioneer new approaches for rapidly developing prototype systems, demonstrating key capabilities and validating operational concepts for future human missions beyond Earth orbit. For more information on Project Morpheus, visit http://morpheuslander.jsc.nasa.gov/. Photo credit: NASA/Frankie Martin
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Extrapolate the Past... or Invent the Future
Vinod Khosla
2017-12-09
Berkeley Lab's Environmental Energy Technologies Division launches its Distinguished Lecturer series with a talk by Vinod Khosla, founder of Khosla Ventures, whose mission is to "assist great entre... Â
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Problems and potentialities of cultured plant cells in retrospect and prospect
NASA Technical Reports Server (NTRS)
Steward, F. C.; Krikorian, A. D.
1979-01-01
The past, present and expected future accomplishments and limitations of plant cell and tissue culture are reviewed. Consideration is given to the pioneering insights of Haberlandt in 1902, the development of culture techniques, and past work on cell division, cell and tissue growth and development, somatic embryogenesis, and metabolism and respiration. Current activity in culture media and technique development for plant regions, organs, tissues, cells, protoplasts, organelles and embryos, totipotency, somatic embryogenesis and clonal propagation under normal and space conditions, biochemical potentialities, and genetic engineering is surveyed. Prospects for the investigation of the induced control of somatic cell division, the division of isolated protoplasts, the improvement of haploid cell cultures, liquid cultures for somatic embryogenesis, and the genetic control of development are outlined.
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Earth Sciences Division Research Summaries 2002-2003
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bodvarsson, G.S.
2003-11-01
Research in earth and atmospheric sciences is becoming increasingly important in light of the energy, climate change, and environmental issues facing the United States and the world. The development of new energy resources other than hydrocarbons and the safe disposal of nuclear waste and greenhouse gases (such as carbon dioxide and methane) are critical to the future energy needs and environmental safety of this planet. In addition, the cleanup of many contaminated sites in the U.S., along with the preservation and management of our water supply, remain key challenges for us as well as future generations. Addressing these energy, climatemore » change, and environmental issues requires the timely integration of earth sciences' disciplines (such as geology, hydrology, oceanography, climatology, geophysics, geochemistry, geomechanics, ecology, and environmental sciences). This integration will involve focusing on fundamental crosscutting concerns that are common to many of these issues. A primary focus will be the characterization, imaging, and manipulation of fluids in the earth. Such capabilities are critical to many DOE applications, from environmental restoration to energy extraction and optimization. The Earth Sciences Division (ESD) of the Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab) is currently addressing many of the key technical issues described above. In this document, we present summaries of many of our current research projects. While it is not a complete accounting, it is representative of the nature and breadth of our research effort. We are proud of our scientific efforts, and we hope that you will find our research useful and exciting. Any comments on our research are appreciated and can be sent to me personally. This report is divided into five sections that correspond to the major research programs in the Earth Sciences Division: (1) Fundamental and Exploratory Research; (2) Nuclear Waste; (3) Energy Resources; (4) Environmental Remediation Technology; and (5) Climate Variability and Carbon Management. These programs draw from each of ESD's disciplinary departments: Microbial Ecology and Environmental Engineering, Geophysics and Geomechanics, Geochemistry, and Hydrogeology and Reservoir Dynamics. Short descriptions of these departments are provided as introductory material. A list of publications for the period from January 2002 to June 2003, along with a listing of our personnel, are appended to the end of this report.« less
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Code of Federal Regulations, 2011 CFR
2011-01-01
...: (a) By mail addressed to: ATTN: Document Control Desk, Director, Division of Security Operations....gov/site-help/e-submittals.html; by e-mail to [email protected]; or by writing the Office of...
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Pressurized grout remote backfilling at AML sites near Beulah and Zap, North Dakota
DOE Office of Scientific and Technical Information (OSTI.GOV)
Weiner, E.J.; Dodd, W.E.
1999-07-01
The Abandoned Mine Lands (AML) Division of the North Dakota Public Service Commission (PSC) is charged with the reclamation of hazardous abandoned mine sites in North Dakota. Several underground lignite coalmines were operated near the cities of Beulah and Zap, North Dakota, from the early 1900's until about 1955. Coal seams in this area were relatively thick and the overburden generally shallow. As these mines have deteriorated with time, deep collapse features, or sinkholes, have surfaced in many areas. These features are very dangerous, especially when they occur at or near residential and commercial areas and public roads. In themore » past five years, sinkholes have surfaced beneath a commercial building (boat dealership, lounge, and gas station) and beneath a nearby occupied mobile home north of Beulah. sinkholes have also surfaced near KHOL Radio Station in Beulah and in the right of way of a public road south of Zap. The AML Division has conducted several emergency sinkhole-filling projects in these areas. In 1995--97, the AML Division conducted exploratory drilling which confirmed the presence of collapsing underground mines at these sites. The remediation of these sites around Beulah/Zap will take place over several years and involve three or more separate contracts due to budget considerations. In 1997, the AML Division began reclamation at these sties utilizing pressurized grout remote backfilling. In this technique, a cementitious grout is pumped through cased drill holes directly into the mine cavities to fill them and thereby stabilize the surface from collapse. The successful contractor for Phase One of the project was The Concrete Doctor, Inc. (TCDI). This paper will concentrate on Phase One of this work performed from June through September 1997. This project is especially interesting because grout was pumped through holes drilled inside the occupied commercial building. Grout was also pumped through angled holes that intercepted mined workings directly beneath the structure. Several specialized monitoring techniques were used to alert contractor if any movement in the structures occurred during grouting activities. Informational meetings were conducted by TCDI and PDC held with landowners, business owners, residents and road authorities before, during and after the project.« less
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Tortorelli, Robert L.
2008-01-01
Water Year 2006 (October 1, 2005, to September 30, 2006) was a year of extreme hydrologic drought and the driest year in the recent 2002-2006 drought in Oklahoma. The severity of this recent drought can be evaluated by comparing it with four previous major hydrologic droughts, water years 1929-41, 1952-56, 1961-72, and 1976-81. The U.S. Geological Survey, in cooperation with the Oklahoma Water Resources Board, completed an investigation to summarize the Water Year 2006 hydrologic drought and compare it to the four previous major hydrologic droughts in the 20th century. The period of water years 1925-2006 was selected as the period of record because before 1925 few continuous record streamflow-gaging sites existed and gaps existed where no streamflow-gaging sites were operated. Statewide annual precipitation in Water Year 2006 was second driest and statewide annual runoff in Water Year 2006 was sixth driest in the 82 years of record. Annual area-averaged precipitation totals by the nine National Weather Service Climate Divisions from Water Year 2006 are compared to those during four previous major hydrologic droughts to show how rainfall deficits in Oklahoma varied by region. Only two of the nine climate divisions, Climate Division 1 Panhandle and Climate Division 4 West Central, had minor rainfall deficits, while the rest of the climate divisions had severe rainfall deficits in Water Year 2006 ranging from only 65 to 73 percent of normal annual precipitation. Regional streamflow patterns for Water Year 2006 indicate that Oklahoma was part of the regionwide below-normal streamflow conditions for Arkansas-White-Red River Basin, the sixth driest since 1930. The percentage of long-term stations in Oklahoma (with at least 30 years of record) having below-normal streamflow reached 80 to 85 percent for some days in August and November 2006. Twelve long-term streamflow-gaging sites with periods of record ranging from 62 to 78 years were selected to show how streamflow deficits varied by region. The hydrologic drought worsened going from north to south in Oklahoma, ranging from 45 percent in the north, to just 14 percent in east-central Oklahoma, and 20 percent of normal annual streamflow in the southwest. The low streamflows resulted in only 86.3 percent of the statewide conservation storage available at the end of the water year in major reservoirs, and 7 to 47 percent of hydroelectric power generation at sites in Oklahoma in Calendar Year 2005.
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, Emeryville, CA Joint Center for Artificial Photosynthesis (JCAP) - Bldg. 976, 2929 7th St., Suite 105 Financial Officer (OCFO) - Bldg. 971, 6401 Hollis St., Emeryville CA Life Sciences Division @ Potter St
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-03-23
...: Heating, ventilating, air-conditioning systems (HVAC), amplifiers, mainboards, gas control modules, hybrid airmeter electronics, hybrid ignition electronics, pressure sensors, transmission control modules, crash...
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Yahashiri, Atsushi; Jorgenson, Matthew A.; Weiss, David S.
2015-01-01
Bacterial SPOR domains bind peptidoglycan (PG) and are thought to target proteins to the cell division site by binding to “denuded” glycan strands that lack stem peptides, but uncertainties remain, in part because septal-specific binding has yet to be studied in a purified system. Here we show that fusions of GFP to SPOR domains from the Escherichia coli cell-division proteins DamX, DedD, FtsN, and RlpA all localize to septal regions of purified PG sacculi obtained from E. coli and Bacillus subtilis. Treatment of sacculi with an amidase that removes stem peptides enhanced SPOR domain binding, whereas treatment with a lytic transglycosylase that removes denuded glycans reduced SPOR domain binding. These findings demonstrate unequivocally that SPOR domains localize by binding to septal PG, that the physiologically relevant binding site is indeed a denuded glycan, and that denuded glycans are enriched in septal PG rather than distributed uniformly around the sacculus. Accumulation of denuded glycans in the septal PG of both E. coli and B. subtilis, organisms separated by 1 billion years of evolution, suggests that sequential removal of stem peptides followed by degradation of the glycan backbone is an ancient feature of PG turnover during bacterial cell division. Linking SPOR domain localization to the abundance of a structure (denuded glycans) present only transiently during biogenesis of septal PG provides a mechanism for coordinating the function of SPOR domain proteins with the progress of cell division. PMID:26305949
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Mechanical stretch triggers rapid epithelial cell division through Piezo1.
Gudipaty, S A; Lindblom, J; Loftus, P D; Redd, M J; Edes, K; Davey, C F; Krishnegowda, V; Rosenblatt, J
2017-03-02
Despite acting as a barrier for the organs they encase, epithelial cells turn over at some of the fastest rates in the body. However, epithelial cell division must be tightly linked to cell death to preserve barrier function and prevent tumour formation. How does the number of dying cells match those dividing to maintain constant numbers? When epithelial cells become too crowded, they activate the stretch-activated channel Piezo1 to trigger extrusion of cells that later die. However, it is unclear how epithelial cell division is controlled to balance cell death at the steady state. Here we show that mammalian epithelial cell division occurs in regions of low cell density where cells are stretched. By experimentally stretching epithelia, we find that mechanical stretch itself rapidly stimulates cell division through activation of the Piezo1 channel. To stimulate cell division, stretch triggers cells that are paused in early G2 phase to activate calcium-dependent phosphorylation of ERK1/2, thereby activating the cyclin B transcription that is necessary to drive cells into mitosis. Although both epithelial cell division and cell extrusion require Piezo1 at the steady state, the type of mechanical force controls the outcome: stretch induces cell division, whereas crowding induces extrusion. How Piezo1-dependent calcium transients activate two opposing processes may depend on where and how Piezo1 is activated, as it accumulates in different subcellular sites with increasing cell density. In sparse epithelial regions in which cells divide, Piezo1 localizes to the plasma membrane and cytoplasm, whereas in dense regions in which cells extrude, it forms large cytoplasmic aggregates. Because Piezo1 senses both mechanical crowding and stretch, it may act as a homeostatic sensor to control epithelial cell numbers, triggering extrusion and apoptosis in crowded regions and cell division in sparse regions.
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PDV2 has a dosage effect on chloroplast division in Arabidopsis.
Chang, Ning; Sun, Qingqing; Li, Yiqiong; Mu, Yajuan; Hu, Jinglei; Feng, Yue; Liu, Xiaomin; Gao, Hongbo
2017-03-01
PDV2 has a dosage effect on chloroplast division in Arabidopsis thaliana , but this effect may vary in different plants. Chloroplasts have to be divided as plants grow to maintain an optimized number in the cell. Chloroplasts are divided by protein complexes across the double membranes from the stroma side to the cytosolic side. PDV2 is a chloroplast division protein on the chloroplast outer membrane. It recruits the dynamin-related GTPase ARC5 to the division site. The C-terminus of PDV2 and the C-terminus of ARC6 interact in the intermembrane space, which is important for the localization of PDV2. Previously, it was shown that overexpression of PDV2 can increase the division of chloroplasts in Arabidopsis and moss, so the authors concluded that PDV2 determines the rate of chloroplast division in land plants. PDV2 was also shown to inhibit the GTPase activity of ARC5 by in vitro experiment. These results look to be contradictory. Here, we identified a null allele of PDV2 in Arabidopsis and studied plants with different levels of PDV2. Our results suggested that the chloroplast division phenotype in Arabidopsis is sensitive to the level of PDV2, while this is not the case for ARC6. The level of PDV2 protein is reduced sharply in fast-growing leaves, while the level of ARC6 is not. The levels of PDV2 and ARC6 in several other plant species at different developmental stages were also investigated. The results indicated that their expression pattern varies in different species. Thus, PDV2 is an important positive factor of chloroplast division with an apparent dosage effect in Arabidopsis, but this effect for different chloroplast division proteins in different plants may vary.
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-05-20
... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-71,711A] Superior Technical Resources and Bestway, Inc., Leased Workers Working On-Site at OSRAM Sylvania, Consumer Lighting Division, a Subsidiary of OSRAM GmbH, St. Marys, PA; Amended Certification Regarding Eligibility To Apply for Worker Adjustment Assistance In accordance with...
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Prescribed burning cost recovery analysis on nonindustrial private forestland in North Carolina
Ronald J. Myers; William Powell; Mark Megalos
2012-01-01
A statewide internal analysis of prescribed burning costs was conducted by the North Carolina Division of Forest Resources (NCDFR) in 2008 to examine the regional differences of site preparation and silvicultural burning costs, and to determine which components were most responsible for losses or gains. This study analyzed actual costs for 90 site preparation (2,559...
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Photographic copy of original design drawing, dated January 1970, revised ...
Photographic copy of original design drawing, dated January 1970, revised 12 March 1971 (original Army Operational Drawing in the possession of U.S. Army Corps of Engineers, Huntsville, Division). MSRPP interior elevations, corridors #216, upper and lower levels - Stanely R. Mickelsen Safeguard Complex, Missile Site Radar Power Plant, Southeast of, & adjacent to, Missile Site Control Building, Nekoma, Cavalier County, ND
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ERIC Educational Resources Information Center
Middlestadt, Susan E.; Sheats, Jylana L.; Geshnizjani, Alireza; Sullivan, Margaret R.; Arvin, Christopher S.
2011-01-01
The purpose of this study was to identify factors underlying decisions to participate in work-site wellness programs. A sample of 279 full-time workers from a service division of a rural Midwestern university completed a survey assessing demographic and job characteristics, health status and health behaviors, and Reasoned Action Approach (RAA)…
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-09-23
... the Division of Migratory Bird Management's Web site at http://www.fws.gov/migratorybirds/ , or at... under ADDRESSES or from our Web site at http://www.fws.gov/migratorybirds/NewsPublicationsReports.html... recommended raising the dark goose daily bag limit from 4 to 5 geese in the aggregate, with the exception of...
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DOE Office of Scientific and Technical Information (OSTI.GOV)
BECHTEL NEVADA
2005-08-01
This Post-Closure Inspection and Monitoring report provides the results of inspections and monitoring for Corrective Action Unit (CAU) 110, Area 3 Waste Management Division (WMD) U-3ax/bl Crater. This report includes an analysis and summary of the site inspections, repairs and maintenance, meteorological information, and soil moisture monitoring data obtained at CAU 110, for the annual period July 2004 through June 2005. Site inspections of the cover were performed quarterly to identify any significant changes to the site requiring action. The overall condition of the cover, cover vegetation, perimeter fence, and use restriction warning signs was good. Settling was observed thatmore » exceeded the action level as specified in Section VII.B.7 of the Hazardous Waste Permit Number NEV HW009 (Nevada Division of Environmental Protection, 2000). This permit states that cracks or settling greater than 15 centimeters (cm) (6 inches [in]) deep that extend 1.0 meter (m) (3 feet [ft]) or more on the cover will be evaluated and repaired within 60 days of detection.« less
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Refernce Conditions for Streams in the Grand Prairie Natural Division of Illinois
NASA Astrophysics Data System (ADS)
Sangunett, B.; Dewalt, R.
2005-05-01
As part of the Critical Trends Assessment Program (CTAP) of the Illinois Department of Natural Resources (IDNR), 12 potential reference quality stream sites in the Grand Prairie Natural Division were evaluated in May 2004. This agriculturally dominated region, located in east central Illinois, is the most highly modified in the state. The quality of these sites was assessed using a modified Hilsenhoff Biotic Index and species richness of Ephemeroptera, Plecoptera, and Trichoptera (EPT) insect orders and a 12 parameter Habitat Quality Index (HQI). Illinois EPA high quality fish stations, Illinois Natural History Survey insect collection data, and best professional knowledge were used to choose which streams to evaluate. For analysis, reference quality streams were compared to 37 randomly selected meandering streams and 26 randomly selected channelized streams which were assessed by CTAP between 1997 and 2001. The results showed that the reference streams exceeded both taxa richness and habitat quality of randomly selected streams in the region. Both random meandering sites and reference quality sites increased in taxa richness and HQI as stream width increased. Randomly selected channelized streams had about the same taxa richness and HQI regardless of width.
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... Web site. rarediseases.org/rare-diseases/dermatomyositis/ . Accessed March 7, 2017. Review Date 2/8/2017 Updated by: Gordon A. Starkebaum, MD, Professor of Medicine, Division of Rheumatology, University of Washington School of Medicine, Seattle, WA. Also reviewed by ...
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AFB Directory of Services Listings
... 520) 770-3268 (TDD/TTY) Arizona Department of Economic Security: Rehabilitation Services Administration 1789 West Jefferson Street, ... Arizona Division Aging and Adult Services Department of Economic Security 1789 W. Jefferson, Site Code 950A-2SW ...
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Midwest Structural Sciences Center, 2006-2013
2013-09-01
for Technology High Speed Systems Division Air Force Research Laboratory This report is published in the interest of scientific and...also be used for making predictions of future flights. 2 Approved for public release; distribution unlimited. Fig. 1.1: Development of future high ...methods were developed to provide validation quality data for coupled high temperature and acoustic loading environments, and to quantitatively study
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Publications - SR 51 | Alaska Division of Geological & Geophysical Surveys
& Geophysical Surveys Comments: Your help is crucial in the compilation of future Alaska Minerals Resources; Fluorine; Geophysics; Germanium; Gold; Heap Leach; Iron; Jade; Lead; Lode; Mercury; Minerals
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NASA Astrophysics Data System (ADS)
Nadal, Laia; Svaluto Moreolo, Michela; Fàbrega, Josep M.; Vílchez, F. Javier
2017-07-01
In this paper, we propose an advanced programmable sliceable-bandwidth variable transceiver (S-BVT) with polarization division multiplexing (PDM) capability as a key enabler to fulfill the requirements for future 5G networks. Thanks to its cost-effective optoelectronic front-end based on orthogonal frequency division multiplexing (OFDM) technology and direct-detection (DD), the proposed S-BVT becomes suitable for next generation highly flexible and scalable metro networks. Polarization beam splitters (PBSs) and controllers (PCs), available on-demand, are included at the transceivers and at the network nodes, further enhancing the system flexibility and promoting an efficient use of the spectrum. 40G-100G PDM transmission has been experimentally demonstrated, within a 4-node photonic mesh network (ADRENALINE testbed), implementing a simplified equalization process.
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Study of the mechanism of diatom cell division by means of 29Si isotope tracing
NASA Astrophysics Data System (ADS)
Audinot, J.-N.; Guignard, C.; Migeon, H.-N.; Hoffmann, L.
2006-07-01
Diatoms are delicate unicellular organisms enclosed in a silica frustule, that is made up of two valves. Multiplication of the diatoms occurs by ordinary mitotic cell division. During cell division each cell produces two daughter cells, each of them keeping one of the two valves of the mother cell and producing a new valve by absorbing the silicon present in the environment. The NanoSIMS 50 allows ion imaging to be performed on diatoms in order to determine the site of fixation of silicon. The aim of this study was to observe and compare the mechanism of the construction of the new valve after cell division. To this end, different types of diatoms have been transferred in a culture medium enriched with 29Si and after several days, the distribution of the different isotopes of silicon has been determined by NanoSIMS50 imaging. The construction of new valves has been observed and the isotopic ratio has been determined.
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Petrogenesis of mare basalts - A record of lunar volcanism
NASA Astrophysics Data System (ADS)
Neal, Clive R.; Taylor, Lawrence A.
1992-06-01
The classification, sources, and overall petrogenesis of mare basalts are reviewed. All mare basalt analyses are used to define a sixfold classification scheme using TiO2 contents as the primary division. A secondary division is made using Al2O3 contents, and a tertiary division is defined using K contents. Such divisions and subdivisions yield a classification containing 12 categories, of which six are accounted for by the existing Apollo and Luna collections. A variety of postmagma-generation such as fractional crystallization, either alone or combined with wallrock assimilation, are invoked to explain the compositional ranges of the various mare basalt suites. High-Ti mare basalts are found at Apollo 1 and Apollo 17 sites; the A-11 basalts contain lower TiO2 abundances, a considerably larger range in trace-element contents, and the only occurrence of high-Ti/high-K mare basalts. The low-Ti basalts exhibit a wide range of major-and trace-element compositions and require source heterogeneity, fractional crystallization, and some assimilation.
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An analysis of the magnitude and frequency of floods on Oahu, Hawaii
Nakahara, R.H.
1980-01-01
An analysis of available peak-flow data for the island of Oahu, Hawaii, was made by using multiple regression techniques which related flood-frequency data to basin and climatic characteristics for 74 gaging stations on Oahu. In the analysis, several different groupings of stations were investigated, including divisions by geographic location and size of drainage area. The grouping consisting of two leeward divisions and one windward division produced the best results. Drainage basins ranged in area from 0.03 to 45.7 square miles. Equations relating flood magnitudes of selected frequencies to basin characteristics were developed for the three divisions of Oahu. These equations can be used to estimate the magnitude and frequency of floods for any site, gaged or ungaged, for any desired recurrence interval from 2 to 100 years. Data on basin characteristics, flood magnitudes for various recurrence intervals from individual station-frequency curves, and computed flood magnitudes by use of the regression equation are tabulated to provide the needed data. (USGS)
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Wölwer, Christina B.; Gödde, Nathan; Pase, Luke B.; Elsum, Imogen A.; Lim, Krystle Y. B.; Sacirbegovic, Faruk; Walkley, Carl R.; Ellis, Sarah; Ohno, Shigeo; Matsuzaki, Fumio; Russell, Sarah M.; Humbert, Patrick O.
2017-01-01
Erythroid enucleation is the process by which the future red blood cell disposes of its nucleus prior to entering the blood stream. This key event during red blood cell development has been likened to an asymmetric cell division (ACD), by which the enucleating erythroblast divides into two very different daughter cells of alternate molecular composition, a nucleated cell that will be removed by associated macrophages, and the reticulocyte that will mature to the definitive erythrocyte. Here we investigated gene expression of members of the Par, Scribble and Pins/Gpsm2 asymmetric cell division complexes in erythroid cells, and functionally tested their role in erythroid enucleation in vivo and ex vivo. Despite their roles in regulating ACD in other contexts, we found that these polarity regulators are not essential for erythroid enucleation, nor for erythroid development in vivo. Together our results put into question a role for cell polarity and asymmetric cell division in erythroid enucleation. PMID:28095473
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NASA Astrophysics Data System (ADS)
Tian, Huiping; Shen, Guansheng; Liu, Weijia; Ji, Yuefeng
2013-07-01
An integrated model of photonic crystal (PC) demultiplexer that can be used to combine dense wavelength-division multiplexing (DWDM) and coarse wavelength-division multiplexing (CWDM) systems is first proposed. By applying the PC demultiplexer, dense channel spacing 0.8 nm and coarse channel spacing 20 nm are obtained at the same time. The transmission can be improved to nearly 90%, and the crosstalk can be decreased to less than -18 dB by enlarging the width of the bus waveguide. The total size of the device is 21×42 μm2. Four channels on one side of the demultiplexer can achieve DWDM in the wavelength range between 1575 and 1578 nm, and the other four channels on the other side can achieve CWDM in the wavelength range between 1490 and 1565 nm, respectively. The demonstrated demultiplexer can be applied in the future CWDM and DWDM system, and the architecture costs can be significantly reduced.
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Environmental Education and Development Division (EM-522). Annual report, Fiscal year 1993
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1993-12-31
The Environmental Education and Development Division (EM-522) is one of three divisions within the Office of Technology Integration and Environmental Education and Development (EM-52) in Environmental Restoration and Waste Management`s (EM`s) Office of Technology Development (EM-50). The primary design criterion for EM-522 education activities is directly related to meeting EM`s goal of environmental compliance on an accelerated basis and cleanup of the 1989 inventory of inactive sites and facilities by the year 2019. Therefore, EM-522`s efforts are directed specifically toward stimulating knowledge and capabilities to achieve the goals of EM while contributing to DOE`s overall goal of increasing scientific, mathematical,more » and technical literacy and competency. This report discusses fiscal year 1993 activities.« less
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Physics and Advanced Technologies 2003 Annual Report
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hazi, A; Sketchley, J
2005-01-20
The Physics and Advanced Technologies (PAT) Directorate overcame significant challenges in 2003 to deliver a wealth of scientific and programmatic milestones, and move toward closer alignment with programs at Lawrence Livermore National Laboratory. We acted aggressively in enabling the PAT Directorate to contribute to future, growing Lawrence Livermore missions in homeland security and at the National Ignition Facility (NIF). We made heavy investments to bring new capabilities to the Laboratory, to initiate collaborations with major Laboratory programs, and to align with future Laboratory directions. Consistent with our mission, we sought to ensure that Livermore programs have access to the bestmore » science and technology, today and tomorrow. For example, in a move aimed at revitalizing the Laboratory's expertise in nuclear and radiation detection, we brought the talented Measurement Sciences Group to Livermore from Lawrence Berkeley National Laboratory, after its mission there had diminished. The transfer to our I Division entailed significant investment by PAT in equipment and infrastructure required by the group. In addition, the move occurred at a time when homeland security funding was expected, but not yet available. By the end of the year, though, the group was making crucial contributions to the radiation detection program at Livermore, and nearly every member was fully engaged in programmatic activities. Our V Division made a move of a different sort, relocating en masse from Building 121 to the NIF complex. This move was designed to enhance interaction and collaboration among high-energy-density experimental scientists at the Laboratory, a goal that is essential to the effective use of NIF in the future. Since then, V Division has become increasingly integrated with NIF activities. Division scientists are heavily involved in diagnostic development and fielding and are poised to perform equation-of-state and high-temperature hohlraum experiments in 2004 as part of the NIF Early Light program.« less
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Fujiwara, Makoto T.; Kojo, Kei H.; Kazama, Yusuke; Sasaki, Shun; Abe, Tomoko; Itoh, Ryuuichi D.
2015-01-01
Plastids in the leaf epidermal cells of plants are regarded as immature chloroplasts that, like mesophyll chloroplasts, undergo binary fission. While mesophyll chloroplasts have generally been used to study plastid division, recent studies have suggested the presence of tissue- or plastid type-dependent regulation of plastid division. Here, we report the detailed morphology of plastids and their stromules, and the intraplastidic localization of the chloroplast division-related protein AtFtsZ1-1, in the leaf epidermis of an Arabidopsis mutant that harbors a mutation in the chloroplast division site determinant gene AtMinE1. In atminE1, the size and shape of epidermal plastids varied widely, which contrasts with the plastid phenotype observed in atminE1 mesophyll cells. In particular, atminE1 epidermal plastids occasionally displayed grape-like morphology, a novel phenotype induced by a plastid division mutation. Observation of an atminE1 transgenic line harboring an AtMinE1 promoter::AtMinE1-yellow fluorescent protein fusion gene confirmed the expression and plastidic localization of AtMinE1 in the leaf epidermis. Further examination revealed that constriction of plastids and stromules mediated by the FtsZ1 ring contributed to the plastid pleomorphism in the atminE1 epidermis. These results illustrate that a single plastid division mutation can have dramatic consequences for epidermal plastid morphology, thereby implying that plastid division and morphogenesis are differentially regulated in epidermal and mesophyll plastids. PMID:26500667
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GOES-R Prelaunch News Conference
2016-11-17
Sandra Smalley, director, Joint Agency Satellite Division, NASA Headquarters, speaks to members of the news media during a Geostationary Operational Environmental Satellite (GOES-R) prelaunch news conference in the Kennedy Space Center's Press Site auditorium in Florida.
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Accurate Cell Division in Bacteria: How Does a Bacterium Know Where its Middle Is?
NASA Astrophysics Data System (ADS)
Howard, Martin; Rutenberg, Andrew
2004-03-01
I will discuss the physical principles lying behind the acquisition of accurate positional information in bacteria. A good application of these ideas is to the rod-shaped bacterium E. coli which divides precisely at its cellular midplane. This positioning is controlled by the Min system of proteins. These proteins coherently oscillate from end to end of the bacterium. I will present a reaction-diffusion model that describes the diffusion of the Min proteins, and their binding/unbinding from the cell membrane. The system possesses an instability that spontaneously generates the Min oscillations, which control accurate placement of the midcell division site. I will then discuss the role of fluctuations in protein dynamics, and investigate whether fluctuations set optimal protein concentration levels. Finally I will examine cell division in a different bacteria, B. subtilis. where different physical principles are used to regulate accurate cell division. See: Howard, Rutenberg, de Vet: Dynamic compartmentalization of bacteria: accurate division in E. coli. Phys. Rev. Lett. 87 278102 (2001). Howard, Rutenberg: Pattern formation inside bacteria: fluctuations due to the low copy number of proteins. Phys. Rev. Lett. 90 128102 (2003). Howard: A mechanism for polar protein localization in bacteria. J. Mol. Biol. 335 655-663 (2004).
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Strategic planning for neuroradiologists.
Berlin, Jonathan W; Lexa, Frank J
2012-08-01
Strategic planning is becoming essential to neuroradiology as the health care environment continues to emphasize cost efficiency, teamwork and collaboration. A strategic plan begins with a mission statement and vision of where the neuroradiology division would like to be in the near future. Formalized strategic planning frameworks, such as the strengths, weaknesses, opportunities and threats (SWOT), and the Balanced Scorecard frameworks, can help neuroradiology divisions determine their current position in the marketplace. Communication, delegation, and accountability in neuroradiology is essential in executing an effective strategic plan. Copyright © 2012 Elsevier Inc. All rights reserved.
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Multi-carrier mobile TDMA system with active array antenna
NASA Technical Reports Server (NTRS)
Suzuki, Ryutaro; Matsumoto, Yasushi; Hamamoto, Naokazu
1990-01-01
A multi-carrier time division multiple access (TDMA) is proposed for the future mobile satellite communications systems that include a multi-satellite system. This TDMA system employs the active array antenna in which the digital beam forming technique is adopted to control the antenna beam direction. The antenna beam forming is carried out at the base band frequency by using the digital signal processing technique. The time division duplex technique is applied for the TDM/TDMA burst format, in order not to overlap transmit and receive timing.
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NASA Technical Reports Server (NTRS)
Emerson, Dawn
2016-01-01
This presentation provides an overview of the research and engineering in the competency fields of advanced communications and intelligent systems with emphasis on advanced technologies, architecture definition and system development for application in current and future aeronautics and space systems.
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Federal Register 2010, 2011, 2012, 2013, 2014
2013-09-06
... NOAA Fisheries Southeast Regional Office, Highly Migratory Species Management Division, and Southeast... describes the fisheries, evaluates the status of the stock, estimates biological benchmarks, projects future...
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40 CFR 52.2630 - Prevention of significant deterioration of air quality.
Code of Federal Regulations, 2014 CFR
2014-07-01
..., including Supplement A, in all PSD permit application reviews. The Division will utilize any future revisions to the Guideline in PSD permitting reviews as revisions become effective. [44 FR 51979, Sept. 6...
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40 CFR 52.2630 - Prevention of significant deterioration of air quality.
Code of Federal Regulations, 2011 CFR
2011-07-01
..., including Supplement A, in all PSD permit application reviews. The Division will utilize any future revisions to the Guideline in PSD permitting reviews as revisions become effective. [44 FR 51979, Sept. 6...
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40 CFR 52.2630 - Prevention of significant deterioration of air quality.
Code of Federal Regulations, 2012 CFR
2012-07-01
..., including Supplement A, in all PSD permit application reviews. The Division will utilize any future revisions to the Guideline in PSD permitting reviews as revisions become effective. [44 FR 51979, Sept. 6...
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40 CFR 52.2630 - Prevention of significant deterioration of air quality.
Code of Federal Regulations, 2013 CFR
2013-07-01
..., including Supplement A, in all PSD permit application reviews. The Division will utilize any future revisions to the Guideline in PSD permitting reviews as revisions become effective. [44 FR 51979, Sept. 6...
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Publications - IC 47 | Alaska Division of Geological & Geophysical Surveys
Surveys Comments: Your help is crucial in the compilation of future Alaska Minerals Reports. The quality ; Placer; Platinum; Precious Metals; Red Dog; Sand and Gravel; Silver; Skarn; Soil Chemistry; Stibnite
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Chang, Yun-Juan; Peacock, Aaron D.; Long, Philip E.; Stephen, John R.; McKinley, James P.; Macnaughton, Sarah J.; Hussain, A. K. M. Anwar; Saxton, Arnold M.; White, David C.
2001-01-01
Microbially mediated reduction and immobilization of U(VI) to U(IV) plays a role in both natural attenuation and accelerated bioremediation of uranium-contaminated sites. To realize bioremediation potential and accurately predict natural attenuation, it is important to first understand the microbial diversity of such sites. In this paper, the distribution of sulfate-reducing bacteria (SRB) in contaminated groundwater associated with a uranium mill tailings disposal site at Shiprock, N.Mex., was investigated. Two culture-independent analyses were employed: sequencing of clone libraries of PCR-amplified dissimilatory sulfite reductase (DSR) gene fragments and phospholipid fatty acid (PLFA) biomarker analysis. A remarkable diversity among the DSR sequences was revealed, including sequences from δ-Proteobacteria, gram-positive organisms, and the Nitrospira division. PLFA analysis detected at least 52 different mid-chain-branched saturate PLFA and included a high proportion of 10me16:0. Desulfotomaculum and Desulfotomaculum-like sequences were the most dominant DSR genes detected. Those belonging to SRB within δ-Proteobacteria were mainly recovered from low-uranium (≤302 ppb) samples. One Desulfotomaculum-like sequence cluster overwhelmingly dominated high-U (>1,500 ppb) sites. Logistic regression showed a significant influence of uranium concentration over the dominance of this cluster of sequences (P = 0.0001). This strong association indicates that Desulfotomaculum has remarkable tolerance and adaptation to high levels of uranium and suggests the organism's possible involvement in natural attenuation of uranium. The in situ activity level of Desulfotomaculum in uranium-contaminated environments and its comparison to the activities of other SRB and other functional groups should be an important area for future research. PMID:11425735
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Information Technology Division’s Technical Paper Abstracts
1994-07-05
antenna systems. 86 Title: An Electromagnetic Interference Study of Potential Transmitter Sites for the HF Active Auroral Research Program ( HAARP ...examined a number of potential sites for the location of the proposed High Frequency Active Auroral Research Program ( HAARP ) transmitter facility. The...proposed HAARP facility will consist of a large planar array of antennas excited by phased high power transmitters operating in the lower portion of the
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Energy, Power and Thermal Research Overview
2010-09-01
Research Overview Rick Fingers, Ph.D. Chief Energy/Power/Thermal Division Propulsion Directorate Air Force Research ... Air Vehicles Sensors AFOSR 5 AFRL People & Facilities • 10 Major R&D Sites across US • 40 Sites World-Wide • $40B Real Property & Capital throughout... AFRL • 5,764 Government Employees – 4570 Air Force Civilian – 1194 Military • 3,844 Onsite Contractors 6 Propulsion Directorate’s Strategic
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Environmental concerns and future oil and gas developments in Coastal Wetlands of Louisiana
DOE Office of Scientific and Technical Information (OSTI.GOV)
John, C.J.; Harder, B.J.; Groat, C.G.
1993-09-01
Recent studies have confirmed that much oil and natural gas have been overlooked and increases in future recoverable reserves will come from drilling in these areas. Increased production will result from identifying unexploited compartmentalized reservoirs, new infield reservoirs, and bypassed reservoirs, and by using enhanced recovery technologies for hydrocarbon recovery in incompletely drained reservoirs previously left unproduced for economic reasons. Most of southern Louisiana's hydrocarbon reserves underlie coastal wetland areas of the state. Major environmental concerns associated with the future development of existing reserves are canal dredging and destruction of wildlife habitat, use and disposal of oil-based muds, mitigation formore » wetland damage, and the recent emerging issue of surface contamination by naturally occurring radioactive materials with potential liabilities and future remedial regulation. To reduce wetland environmental damage caused by access canals to drilling sites, the Coastal Management Division of the Louisiana Department of Natural Resources instituted a geologic reviews program to review drilling permit application in the coastal wetlands. This process provides a mechanism for state and federal agencies to comment on the requested drilling permit. As a result of this process, the total average wetland disturbed area has been reduced from 767 ac per year in 1982 to approximately 76 ac per year in 1991. Average lengths of access canals also have been reduced by approximately 78% during the period. Oil and gas companies are becoming increasingly aware of the environmental consequences of drilling in wetlands and are considering them in planning for development activities. In the current climate of increasing public consciousness about the environment, addressing environmental concerns in the planning state will go a long way in helping alleviate future environmental problems.« less
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Wang, Ning; Lee, I-Ju; Rask, Galen; Wu, Jian-Qiu
2016-01-01
The cleavage-furrow tip adjacent to the actomyosin contractile ring is believed to be the predominant site for plasma-membrane insertion through exocyst-tethered vesicles during cytokinesis. Here we found that most secretory vesicles are delivered by myosin-V on linear actin cables in fission yeast cytokinesis. Surprisingly, by tracking individual exocytic and endocytic events, we found that vesicles with new membrane are deposited to the cleavage furrow relatively evenly during contractile-ring constriction, but the rim of the cleavage furrow is the main site for endocytosis. Fusion of vesicles with the plasma membrane requires vesicle tethers. Our data suggest that the transport particle protein II (TRAPP-II) complex and Rab11 GTPase Ypt3 help to tether secretory vesicles or tubulovesicular structures along the cleavage furrow while the exocyst tethers vesicles at the rim of the division plane. We conclude that the exocyst and TRAPP-II complex have distinct localizations at the division site, but both are important for membrane expansion and exocytosis during cytokinesis. PMID:27082518
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ERIC Educational Resources Information Center
Herzog, A. Regula; And Others
In order to describe in detail adolescents' preferences for the division of labor between husband and wife, including the flexibility inherent in the various alternatives, to assess changes in these preferences over recent years, and to explore potential correlates, data from the Monitoring the Future Survey, a large annual survey of high school…
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Swarzenski, Peter W.; Storlazzi, Curt D.; Presto, M. Katherine; Gibbs, Ann E.; Smith, Christopher G.; Dimova, Natasha T.; Dailer, Meghan L.; Logan, Joshua B.
2012-01-01
This report presents a brief summary of recent fieldwork conducted off Kahekili Beach Park, Maui, Hawaii, the site of the newly established U.S. Coral Reef Task Force priority study area at Kaanapali and the Hawaii Department of Land and Natural Resources, Division of Aquatic Resources, Kahekili Herbivore Fisheries Management Area (HFMA). The goals of this fieldwork are to provide new baseline information to help guide future studies and to provide first insights into rates and drivers of coastal groundwater discharge and associated constituent loadings into the priority study area's coastal waters. This study presents the first swath acoustic mapping information, in situ oceanographic instrument measurements, and coastal groundwater discharge estimates at this site based on the submarine groundwater discharge tracer radon-222 (222Rn). Coastal groundwater discharge rates ranged from about 22 to 50 centimeters per day, depending on proximity of the sampling mooring to the primary discharge vent. The water chemistry of the discharging groundwater was at times dramatically different than ambient seawater. For example, at the primary vent site at Kahekili, the concentrations of total dissolved nitrogen (TDN), dissolved silicate (DSi), and total dissolved phosphorus (TDP) in the discharging groundwater were 43.75 micromolar (μM), 583.49 μM, and 12.04 μM, respectively. These data extend our basic understanding of the morphology, benthic structure, and oceanographic setting of this vent site and provide a first estimate of the magnitude and physical forcings of submarine groundwater discharge and associated trace metals and nutrient loads here.
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Litter survey : status report 1.
DOT National Transportation Integrated Search
1979-01-01
At the request of the Division of Litter Control of the Department of Conservation and Economic Development, the Research Council has initiated a litter survey program at approximately 25 sites on the state highway system. The purpose of this program...
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78 FR 766 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance
Federal Register 2010, 2011, 2012, 2013, 2014
2013-01-04
..., 2012. Branding and Information Solutions Division (RBIS), Adecco. 82,139A Leased Workers From Lenoir, NC November 8, 2011. Manpower, Working On-Site At Avery Dennison, Retail Branding and Inform (RBIS...
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The 10 Hottest Technologies in Telecom.
ERIC Educational Resources Information Center
Flanagan, Patrick
1997-01-01
Presents the fourth annual listing of the 10 "hottest" telecommunications technologies. Describes Web broadcasting, remote-access servers, extranets, Internet telephony, enterprise network directory services, Web site management tools, IP (Internet Protocols) switching, wavelength division multiplexing, digital subscriber lines, and…
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NASA Technical Reports Server (NTRS)
Garcia, Joseph A.; Smith, Charles A. (Technical Monitor)
1998-01-01
The document consists of a publicly available web site (george.arc.nasa.gov) for Joseph A. Garcia's personal web pages in the AI division. Only general information will be posted and no technical material. All the information is unclassified.
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Cooperative Training Partnership in Aquatic Toxicology and Ecosystem Research
EPA-ORD seeks applications to enter into a cooperative agreement with EPA that will provide training opportunities for undergraduate, graduate, and post-doctoral trainees on-site at ORD’s Mid-Continent Ecology Division (MED) research
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Studying Production Technology for the World of the Future
ERIC Educational Resources Information Center
Pinder, Charles A.; Ritz, John M.
1977-01-01
After tracing the evolving concept of production technology during the past century the authors define its divisions as construction, manufacturing, and processing, and talk about recent developments in the field, with implications for education. (MF)
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Communications and Intelligent Systems Division Overview
NASA Technical Reports Server (NTRS)
Emerson, Dawn
2016-01-01
This presentation provides an overview of the research and engineering in the competency fieldsof advanced communications and intelligent systems with emphasis on advanced technologies, architecture definitionand system development for application in current and future aeronautics and space systems.
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Publications - IC 45 | Alaska Division of Geological & Geophysical Surveys
Surveys Comments: Your help is crucial in the compilation of future Alaska Minerals Reports. The quality ; Production Data; Rocks; Sand and Gravel; Silver; Soapstone; Tin; Zinc Top of Page Department of Natural
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Publications - IC 43 | Alaska Division of Geological & Geophysical Surveys
Surveys Comments: Your help is crucial in the compilation of future Alaska Minerals Reports. The quality Assessment; Sand and Gravel; Silver; Soapstone; Soils; Tin; Zinc Top of Page Department of Natural Resources
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NASA Astrophysics Data System (ADS)
Roos, U.-P.
1984-03-01
Based on the assumption that the ancestral proto-eukaryote evolved from an ameboid prokarybte I propose the hypothesis that nuclear division of the proto-eukaryote was effected by the same system of contractile filaments it used for ameboid movement and cytosis. When the nuclear membranes evolved from the cell membrane, contractile filaments remained associated with them. The attachment site of the genome in the nuclear envelope was linked to the cell membrane by specialized contractile filaments. During protomitosis, i.e., nuclear and cell division of the proto-eukaryote, these filaments performed segregation of the chromosomes, whereas others constricted and cleaved the nucleus and the mother cell. When microtubules (MTs) had evolved in the cytoplasm, they also became engaged in nuclear division. Initially, an extranuolear bundle of MTs assisted chromosome segregation by establishing a defined axis. The evolutionary tendency then was towards an increasingly important role for MTs. Spindle pole bodies (SPBs) developed from the chromosomal attachment sites in the nuclear envelope and organized an extranuclear central spindle. The chromosomes remained attached to the SPBs during nuclear division. In a subsequent step the spindle became permanently lodged inside the nucleus. Chromosomes detached from the SPBs and acquired kinetochores and kinetochore-MTs. At first, this spindle segregated chromosomes by elongation, the kinetochore-MTs playing the role of static anchors. Later, spindle elongation was supplemented by poleward movement of the chromosomes. When dissolution of the nuclear envelope at the beginning of mitosis became a permanent feature, the open spindle of higher eukaryotes was born.
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NASA Technical Reports Server (NTRS)
Hand, Zachary
2014-01-01
Over the summer I had the exciting opportunity to work for NASA at the Kennedy Space Center as a Mission Assurance Engineering intern. When I was offered a position in mission assurance for the Safety and Mission Assurance directorate's Launch Services Division, I didn't really know what I would be doing, but I knew it would be an excellent opportunity to learn and grow professionally. In this report I will provide some background information on the Launch Services Division, as well as detail my duties and accomplishments during my time as an intern. Additionally, I will relate the significance of my work experience to my current academic work and future career goals. This report contains background information on Mission Assurance Engineering, a description of my duties and accomplishments over the summer of 2014, and relates the significance of my work experience to my school work and future career goals. It is a required document for the Pathways program.
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Hocking, Jason; Priyadarshini, Richa; Takacs, Constantin N; Costa, Teresa; Dye, Natalie A; Shapiro, Lucy; Vollmer, Waldemar; Jacobs-Wagner, Christine
2012-06-01
The synthesis of the peptidoglycan cell wall is carefully regulated in time and space. In nature, this essential process occurs in cells that live in fluctuating environments. Here we show that the spatial distributions of specific cell wall proteins in Caulobacter crescentus are sensitive to small external osmotic upshifts. The penicillin-binding protein PBP2, which is commonly branded as an essential cell elongation-specific transpeptidase, switches its localization from a dispersed, patchy pattern to an accumulation at the FtsZ ring location in response to osmotic upshifts as low as 40 mosmol/kg. This osmolality-dependent relocation to the division apparatus is initiated within less than a minute, while restoration to the patchy localization pattern is dependent on cell growth and takes 1 to 2 generations. Cell wall morphogenetic protein RodA and penicillin-binding protein PBP1a also change their spatial distribution by accumulating at the division site in response to external osmotic upshifts. Consistent with its ecological distribution, C. crescentus displays a narrow range of osmotolerance, with an upper limit of 225 mosmol/kg in minimal medium. Collectively, our findings reveal an unsuspected level of environmental regulation of cell wall protein behavior that is likely linked to an ecological adaptation.
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Effective GTP-replacing FtsZ inhibitors and antibacterial mechanism of action.
Artola, Marta; Ruiz-Avila, Laura B; Vergoñós, Albert; Huecas, Sonia; Araujo-Bazán, Lidia; Martín-Fontecha, Mar; Vázquez-Villa, Henar; Turrado, Carlos; Ramírez-Aportela, Erney; Hoegl, Annabelle; Nodwell, Matthew; Barasoain, Isabel; Chacón, Pablo; Sieber, Stephan A; Andreu, Jose M; López-Rodríguez, María L
2015-03-20
Essential cell division protein FtsZ is considered an attractive target in the search for antibacterials with novel mechanisms of action to overcome the resistance problem. FtsZ undergoes GTP-dependent assembly at midcell to form the Z-ring, a dynamic structure that evolves until final constriction of the cell. Therefore, molecules able to inhibit its activity will eventually disrupt bacterial viability. In this work, we report a new series of small molecules able to replace GTP and to specifically inhibit FtsZ, blocking the bacterial division process. These new synthesized inhibitors interact with the GTP-binding site of FtsZ (Kd = 0.4-0.8 μM), display antibacterial activity against Gram-positive pathogenic bacteria, and show selectivity against tubulin. Biphenyl derivative 28 stands out as a potent FtsZ inhibitor (Kd = 0.5 μM) with high antibacterial activity [MIC (MRSA) = 7 μM]. In-depth analysis of the mechanism of action of compounds 22, 28, 33, and 36 has revealed that they act as effective inhibitors of correct FtsZ assembly, blocking bacterial division and thus leading to filamentous undivided cells. These findings provide a compelling rationale for the development of compounds targeting the GTP-binding site as antibacterial agents and open the door to antibiotics with novel mechanisms of action.
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NASA Technical Reports Server (NTRS)
Leveton, L. B.; VanderArk, S. T.
2014-01-01
The Behavioral Health and Performance discipline at NASA Johnson Space Center is organized into two distinct Divisions (Biomedical Research and Environmental Science Division and Space and Clinical Operations Division) but is integrated and interrelated in its day-to-day work. Ongoing operations supporting NASA's spaceflight goals benefit from the research portfolios that address risks to mission success. Similarly, these research portfolios are informed by operations to ensure investigations stay relevant given the dynamic environment of spaceflight. There are many success stories that can be presented where initial work begun as a BHP Research project, and funded through the Human Research Program, was fully implemented in operations or addressed an operational need. Examples include improving effectiveness of the debriefings used within Mission Control by the Mission Operations Directorate and countermeasures for fatigue management. There is also ongoing collaboration with research and operations for developing selection methods for future generation astronauts, and to enhance and inform the current family support function. The objective of this panel is to provide examples of recent success stories, describe areas where close collaboration is benefitting ongoing research and operations, and summarize how this will come together as NASA plans for the one year ISS mission - a unique opportunity for both BHP operations and research to learn more about preparing and supporting crewmembers for extended missions in space. The proposed panel will be comprised of six presentations, each describing a unique aspect of research or operations and the benefits to current and future spaceflight.
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Quantification of Uncertainty in the Remedial Investigation/Feasibility Studies Process
1993-09-01
Environmental Restoration Division, HQ Air Combat Command at Langley AFB . Without his support this thesis would not have been possible. Through his...Lester, Restoration Program Manager, Wright-Patterson AFB , stated that the Operable Units (OUs) at Wright- Patterson AFB were regrouped (sites moved...provided detailed information on each installation’s sites and OUs and how they were related. For example, the MAP for Hamilton AFB might describe how
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Site Characterization for Radar Experiments
1990-08-01
accomplished waz "New Mine Detection Technologies," Mr. Jack Stoll, Principal Investigator. The Environmental Systems Division (EST) of the Environmental...Mr. Steve Bong of Hilton Systems visiting the proposed study site in M’rch to select specific locations for the test plots. The field data coll in...Technology/Lincoln Laboratory (MIT/LL) described an airborne 35-Ghz radar imaging system . The MIT/LL would employ various kinds of processing on the
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76 FR 40144 - Semiannual Regulatory Agenda
Federal Register 2010, 2011, 2012, 2013, 2014
2011-07-07
... the Small Business Administration's regulations establishing the Women-Owned Small Business Program... Government's rulemaking Web site at http://www.regulations.gov . FOR FURTHER INFORMATION CONTACT: Hada Flowers, Division Director, Regulatory Secretariat Director, Room 783E, 1275 First Street, NE., Washington...
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41 CFR 102-33.35 - How can we get help in carrying out our responsibilities?
Code of Federal Regulations, 2010 CFR
2010-07-01
....20); or (b) Find more information on the Internet from the following Web sites: (1) http://www.gsa.gov/aircraftpolicy (GSA Aircraft Management Policy Division). (2) http://www.gsa.gov/travelpolicy (GSA...
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-10-01
... on August 23, 2012 (77 FR 51066). Fasco is a warehouse and distribution center for electric motors... and distribution of electric motors, as well as engineering, customer service and information...
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41 CFR 102-33.35 - How can we get help in carrying out our responsibilities?
Code of Federal Regulations, 2013 CFR
2013-07-01
....20); or (b) Find more information on the Internet from the following Web sites: (1) http://www.gsa.gov/aircraftpolicy (GSA Aircraft Management Policy Division). (2) http://www.gsa.gov/travelpolicy (GSA...
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41 CFR 102-33.35 - How can we get help in carrying out our responsibilities?
Code of Federal Regulations, 2014 CFR
2014-01-01
....20); or (b) Find more information on the Internet from the following Web sites: (1) http://www.gsa.gov/aircraftpolicy (GSA Aircraft Management Policy Division). (2) http://www.gsa.gov/travelpolicy (GSA...
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41 CFR 102-33.35 - How can we get help in carrying out our responsibilities?
Code of Federal Regulations, 2012 CFR
2012-01-01
....20); or (b) Find more information on the Internet from the following Web sites: (1) http://www.gsa.gov/aircraftpolicy (GSA Aircraft Management Policy Division). (2) http://www.gsa.gov/travelpolicy (GSA...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-03-10
... subject firm. The workers are engaged in the production of office furniture. The review shows that on... workers of Steelcase, Inc., Global Headquarters, Grand Rapids, Michigan, separated from employment on or...
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3rd Annual NASA Ames Space Science and Astrobiology Jamboree
NASA Technical Reports Server (NTRS)
Dotson, Jessie
2015-01-01
The Space Science and Astrobiology Division at NASA Ames Research Center consists of over 50 civil servants and more than 110 contractors, co--ops, post--docs and associates. Researchers in the division are pursuing investigations in a variety of fields including exoplanets, planetary science, astrobiology and astrophysics. In addition, division personnel support a wide variety of NASA missions including (but not limited to) Kepler, SOFIA, LADEE, JWST, and New Horizons. With such a wide variety of interesting research going on, distributed among three branches in at least 5 different buildings, it can be difficult to stay abreast of what one's fellow researchers are doing. Our goal in organizing this symposium is to facilitate communication and collaboration among the scientists within the division, and to give center management and other ARC researchers and engineers an opportunity to see what scientific research and science mission work is being done in the division. We are also continuing the tradition within the Space Science and Astrobiology Division to honor one senior and one early career scientist with the Pollack Lecture and the Early Career Lecture, respectively. With the Pollack Lecture, our intent is to select a senior researcher who has made significant contributions to any area of research within the space sciences, and we are pleased to honor Dr. William Borucki this year. With the Early Career Lecture, our intent is to select a young researcher within the division who, by their published scientific papers, shows great promise for the future in any area of space science research, and we are pleased to honor Dr. Melinda Kahre this year
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Raslan, Ashraf; Volk, Gerd Fabian; Möller, Martin; Stark, Vincent; Eckhardt, Nikolas; Guntinas-Lichius, Orlando
2017-06-01
To examine by intraoperative electric stimulation which peripheral facial nerve (FN) branches are functionally connected to which facial muscle functions. Single-center prospective clinical study. Seven patients whose peripheral FN branching was exposed during parotidectomy under FN monitoring received a systematic electrostimulation of each branch starting with 0.1 mA and stepwise increase to 2 mA with a frequency of 3 Hz. The electrostimulation and the facial and neck movements were video recorded simultaneously and evaluated independently by two investigators. A uniform functional allocation of specific peripheral FN branches to a specific mimic movement was not possible. Stimulation of the whole spectrum of branches of the temporofacial division could lead to eye closure (orbicularis oculi muscle function). Stimulation of the spectrum of nerve branches of the cervicofacial division could lead to reactions in the midface (nasal and zygomatic muscles) as well as around the mouth (orbicularis oris and depressor anguli oris muscle function). Frontal and eye region were exclusively supplied by the temporofacial division. The region of the mouth and the neck was exclusively supplied by the cervicofacial division. Nose and zygomatic region were mainly supplied by the temporofacial division, but some patients had also nerve branches of the cervicofacial division functionally supplying the nasal and zygomatic region. FN branches distal to temporofacial and cervicofacial division are not necessarily covered by common facial nerve monitoring. Future bionic devices will need a patient-specific evaluation to stimulate the correct peripheral nerve branches to trigger distinct muscle functions. 4 Laryngoscope, 127:1288-1295, 2017. © 2016 The American Laryngological, Rhinological and Otological Society, Inc.
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A Report of the Nuclear Engineering Division Sessions at the 1971 ASEE Annual Conference
ERIC Educational Resources Information Center
Eckley, Wayne; Nelson, George W.
1972-01-01
Summarizes the discussions at the conference under the topics, Objective Criteria for the Future" and Teaching Concepts Basic to Nuclear Engineering." Includes comments from personnel representing universities, industries, and government laboratories. (TS)
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Global Energy: Supply, Demand, Consequences, Opportunities
Majumdar, Arun
2017-12-09
July 29, 2008 Berkeley Lab lecture: Arun Majumdar, Director of the Environmental Energy Technologies Division, discusses current and future projections of economic growth, population, and global energy demand and supply, and explores the implications of these trends for the environment.
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Cancer Prevention Fellowship Program Aims for High Marks | Division of Cancer Prevention
For nearly 30 years, the NCI Cancer Prevention Fellowship Program (CPFP) has provided funding support for post-doctoral Fellows with a goal to train the future generation of researchers and leaders in the field. |
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The 1994 Louisiana Maneuvers: Is Back to the Future What Our Army Needs?
1992-05-26
can link current operational level training to future Combined Arms Training Strategies ( CATS ). The Army Chief of Staff s 1994 Louisiana Maneuver...tactical Combined Arms Training Strategy ( CATS ). An examination of Army tactical training strategies will reflect that operational forces can benefit...from both a CATS structure, and participation in an operational level Battle Command Training Program (BCTP) similar to division and corps BCTP’s
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Morpheus Alhat Tether Test Preparations
2014-03-27
CAPE CANAVERAL, Fla. – Technicians watch as a crane lowers the Project Morpheus prototype lander onto a launch pad at a new launch site at the north end of the Shuttle Landing Facility at NASA's Kennedy Space Center in Florida. Preparations are underway for a tether test. The launch pad was moved to a different location at the landing facility to support the next phase of flight testing. Project Morpheus tests NASA’s automated landing and hazard avoidance technology, or ALHAT, and an engine that runs on liquid oxygen and methane, or green propellants, into a fully-operational lander that could deliver cargo to other planetary surfaces. The landing facility provides the lander with the kind of field necessary for realistic testing, complete with rocks, craters and hazards to avoid. Morpheus’ ALHAT payload allows it to navigate to clear landing sites amidst rocks, craters and other hazards during its descent. Project Morpheus is being managed under the Advanced Exploration Systems, or AES, Division in NASA’s Human Exploration and Operations Mission Directorate. The efforts in AES pioneer new approaches for rapidly developing prototype systems, demonstrating key capabilities and validating operational concepts for future human missions beyond Earth orbit. For more information on Project Morpheus, visit http://morpheuslander.jsc.nasa.gov/. Photo credit: NASA/Ben Smegelsky
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Morpheus Alhat Tether Test Preparations
2014-03-27
CAPE CANAVERAL, Fla. – A crane lowers the Project Morpheus prototype lander onto a launch pad at a new launch site at the north end of the Shuttle Landing Facility at NASA's Kennedy Space Center in Florida. Preparations are underway for a tether test. The launch pad was moved to a different location at the landing facility to support the next phase of flight testing. Project Morpheus tests NASA’s automated landing and hazard avoidance technology, or ALHAT, and an engine that runs on liquid oxygen and methane, or green propellants, into a fully-operational lander that could deliver cargo to other planetary surfaces. The landing facility provides the lander with the kind of field necessary for realistic testing, complete with rocks, craters and hazards to avoid. Morpheus’ ALHAT payload allows it to navigate to clear landing sites amidst rocks, craters and other hazards during its descent. Project Morpheus is being managed under the Advanced Exploration Systems, or AES, Division in NASA’s Human Exploration and Operations Mission Directorate. The efforts in AES pioneer new approaches for rapidly developing prototype systems, demonstrating key capabilities and validating operational concepts for future human missions beyond Earth orbit. For more information on Project Morpheus, visit http://morpheuslander.jsc.nasa.gov/. Photo credit: NASA/Ben Smegelsky
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Morpheus Alhat Tether Test Preparations
2014-03-27
CAPE CANAVERAL, Fla. – Engineers and technicians monitor the progress as a crane lifts the Project Morpheus prototype lander off the ground for a tether test near a new launch site at the north end of the Shuttle Landing Facility at NASA's Kennedy Space Center in Florida. The launch pad was moved to a different location at the landing facility to support the next phase of flight testing. Project Morpheus tests NASA’s automated landing and hazard avoidance technology, or ALHAT, and an engine that runs on liquid oxygen and methane, or green propellants, into a fully-operational lander that could deliver cargo to other planetary surfaces. The landing facility provides the lander with the kind of field necessary for realistic testing, complete with rocks, craters and hazards to avoid. Morpheus’ ALHAT payload allows it to navigate to clear landing sites amidst rocks, craters and other hazards during its descent. Project Morpheus is being managed under the Advanced Exploration Systems, or AES, Division in NASA’s Human Exploration and Operations Mission Directorate. The efforts in AES pioneer new approaches for rapidly developing prototype systems, demonstrating key capabilities and validating operational concepts for future human missions beyond Earth orbit. For more information on Project Morpheus, visit http://morpheuslander.jsc.nasa.gov/. Photo credit: NASA/Ben Smegelsky
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Morpheus Campaign 2A Tether Test
2014-03-27
CAPE CANAVERAL, Fla. – NASA's Project Morpheus prototype lander is positioned near a new launch site at the north end of the Shuttle Landing Facility at NASA’s Kennedy Space Center in Florida for a tethered test. The test will be performed to verify the lander's recently installed autonomous landing and hazard avoidance technology, or ALHAT, sensors and integration system. The launch pad was moved to a different location at the landing facility to support the next phase of flight testing. Project Morpheus tests NASA’s ALHAT, and an engine that runs on liquid oxygen and methane, or green propellants, into a fully-operational lander that could deliver cargo to other planetary surfaces. The landing facility provides the lander with the kind of field necessary for realistic testing, complete with rocks, craters and hazards to avoid. Morpheus’ ALHAT payload allows it to navigate to clear landing sites amidst rocks, craters and other hazards during its descent. Project Morpheus is being managed under the Advanced Exploration Systems, or AES, Division in NASA’s Human Exploration and Operations Mission Directorate. The efforts in AES pioneer new approaches for rapidly developing prototype systems, demonstrating key capabilities and validating operational concepts for future human missions beyond Earth orbit. For more information on Project Morpheus, visit http://morpheuslander.jsc.nasa.gov/. Photo credit: NASA/Glenn Benson
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Morpheus Alhat Tether Test Preparations
2014-03-27
CAPE CANAVERAL, Fla. – NASA's Project Morpheus prototype lander is positioned near a new launch site at the north end of the Shuttle Landing Facility at NASA’s Kennedy Space Center in Florida for a tether test. The launch pad was moved to a different location at the landing facility to support the next phase of flight testing. Project Morpheus tests NASA’s automated landing and hazard avoidance technology, or ALHAT, and an engine that runs on liquid oxygen and methane, or green propellants, into a fully-operational lander that could deliver cargo to other planetary surfaces. In the foreground of the photo is the ALHAT field. The landing facility provides the lander with the kind of field necessary for realistic testing, complete with rocks, craters and hazards to avoid. Morpheus’ ALHAT payload allows it to navigate to clear landing sites amidst rocks, craters and other hazards during its descent. Project Morpheus is being managed under the Advanced Exploration Systems, or AES, Division in NASA’s Human Exploration and Operations Mission Directorate. The efforts in AES pioneer new approaches for rapidly developing prototype systems, demonstrating key capabilities and validating operational concepts for future human missions beyond Earth orbit. For more information on Project Morpheus, visit http://morpheuslander.jsc.nasa.gov/. Photo credit: NASA/Ben Smegelsky
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EPIC-Simulated and MODIS-Derived Leaf Area Index (LAI) ...
Leaf Area Index (LAI) is an important parameter in assessing vegetation structure for characterizing forest canopies over large areas at broad spatial scales using satellite remote sensing data. However, satellite-derived LAI products can be limited by obstructed atmospheric conditions yielding sub-optimal values, or complete non-returns. The United States Environmental Protection Agency’s Exposure Methods and Measurements and Computational Exposure Divisions are investigating the viability of supplemental modelled LAI inputs into satellite-derived data streams to support various regional and local scale air quality models for retrospective and future climate assessments. In this present study, one-year (2002) of plot level stand characteristics at four study sites located in Virginia and North Carolina are used to calibrate species-specific plant parameters in a semi-empirical biogeochemical model. The Environmental Policy Integrated Climate (EPIC) model was designed primarily for managed agricultural field crop ecosystems, but also includes managed woody species that span both xeric and mesic sites (e.g., mesquite, pine, oak, etc.). LAI was simulated using EPIC at a 4 km2 and 12 km2 grid coincident with the regional Community Multiscale Air Quality Model (CMAQ) grid. LAI comparisons were made between model-simulated and MODIS-derived LAI. Field/satellite-upscaled LAI was also compared to the corresponding MODIS LAI value. Preliminary results show field/satel
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Progress on the FabrIc for Frontier Experiments project at Fermilab
Box, Dennis; Boyd, Joseph; Dykstra, Dave; ...
2015-12-23
The FabrIc for Frontier Experiments (FIFE) project is an ambitious, major-impact initiative within the Fermilab Scientific Computing Division designed to lead the computing model for Fermilab experiments. FIFE is a collaborative effort between experimenters and computing professionals to design and develop integrated computing models for experiments of varying needs and infrastructure. The major focus of the FIFE project is the development, deployment, and integration of Open Science Grid solutions for high throughput computing, data management, database access and collaboration within experiment. To accomplish this goal, FIFE has developed workflows that utilize Open Science Grid sites along with dedicated and commercialmore » cloud resources. The FIFE project has made significant progress integrating into experiment computing operations several services including new job submission services, software and reference data distribution through CVMFS repositories, flexible data transfer client, and access to opportunistic resources on the Open Science Grid. Hence, the progress with current experiments and plans for expansion with additional projects will be discussed. FIFE has taken a leading role in the definition of the computing model for Fermilab experiments, aided in the design of computing for experiments beyond Fermilab, and will continue to define the future direction of high throughput computing for future physics experiments worldwide« less
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Antibiotic resistance in Staphylococcus aureus. Current status and future prospects.
Foster, Timothy J
2017-05-01
The major targets for antibiotics in staphylococci are (i) the cell envelope, (ii) the ribosome and (iii) nucleic acids. Several novel targets emerged from recent targeted drug discovery programmes including the ClpP protease and FtsZ from the cell division machinery. Resistance can either develop by horizontal transfer of resistance determinants encoded by mobile genetic elements viz plasmids, transposons and the staphylococcal cassette chromosome or by mutations in chromosomal genes. Horizontally acquired resistance can occur by one of the following mechanisms: (i) enzymatic drug modification and inactivation, (ii) enzymatic modification of the drug binding site, (iii) drug efflux, (iv) bypass mechanisms involving acquisition of a novel drug-resistant target, (v) displacement of the drug to protect the target. Acquisition of resistance by mutation can result from (i) alteration of the drug target that prevents the inhibitor from binding, (ii) derepression of chromosomally encoded multidrug resistance efflux pumps and (iii) multiple stepwise mutations that alter the structure and composition of the cell wall and/or membrane to reduce drug access to its target. This review focuses on development of resistance to currently used antibiotics and examines future prospects for new antibiotics and informed use of drug combinations. © FEMS 2017. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.
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DOE Office of Scientific and Technical Information (OSTI.GOV)
Box, D.; Boyd, J.; Di Benedetto, V.
2016-01-01
The FabrIc for Frontier Experiments (FIFE) project is an initiative within the Fermilab Scientific Computing Division designed to steer the computing model for non-LHC Fermilab experiments across multiple physics areas. FIFE is a collaborative effort between experimenters and computing professionals to design and develop integrated computing models for experiments of varying size, needs, and infrastructure. The major focus of the FIFE project is the development, deployment, and integration of solutions for high throughput computing, data management, database access and collaboration management within an experiment. To accomplish this goal, FIFE has developed workflows that utilize Open Science Grid compute sites alongmore » with dedicated and commercial cloud resources. The FIFE project has made significant progress integrating into experiment computing operations several services including a common job submission service, software and reference data distribution through CVMFS repositories, flexible and robust data transfer clients, and access to opportunistic resources on the Open Science Grid. The progress with current experiments and plans for expansion with additional projects will be discussed. FIFE has taken the leading role in defining the computing model for Fermilab experiments, aided in the design of experiments beyond those hosted at Fermilab, and will continue to define the future direction of high throughput computing for future physics experiments worldwide.« less
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DOE Office of Scientific and Technical Information (OSTI.GOV)
Spittler, T.E.; Sydnor, R.H.; Manson, M.W.
1990-01-01
The Loma Prieta earthquake of October 17, 1989 triggered landslides throughout the Santa Cruz Mountains in central California. The California Department of Conservation, Division of Mines and Geology (DMG) responded to a request for assistance from the County of Santa Cruz, Office of Emergency Services to evaluate the geologic hazard from major reactivated large landslides. DMG prepared a set of geologic maps showing the landslide features that resulted from the October 17 earthquake. The principal purpose of large-scale mapping of these landslides is: (1) to provide county officials with regional landslide information that can be used for timely recovery ofmore » damaged areas; (2) to identify disturbed ground which is potentially vulnerable to landslide movement during winter rains; (3) to provide county planning officials with timely geologic information that will be used for effective land-use decisions; (4) to document regional landslide features that may not otherwise be available for individual site reconstruction permits and for future development.« less
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Technology for national asset storage systems
NASA Technical Reports Server (NTRS)
Coyne, Robert A.; Hulen, Harry; Watson, Richard
1993-01-01
An industry-led collaborative project, called the National Storage Laboratory, was organized to investigate technology for storage systems that will be the future repositories for our national information assets. Industry participants are IBM Federal Systems Company, Ampex Recording Systems Corporation, General Atomics DISCOS Division, IBM ADSTAR, Maximum Strategy Corporation, Network Systems Corporation, and Zitel Corporation. Industry members of the collaborative project are funding their own participation. Lawrence Livermore National Laboratory through its National Energy Research Supercomputer Center (NERSC) will participate in the project as the operational site and the provider of applications. The expected result is an evaluation of a high performance storage architecture assembled from commercially available hardware and software, with some software enhancements to meet the project's goals. It is anticipated that the integrated testbed system will represent a significant advance in the technology for distributed storage systems capable of handling gigabyte class files at gigabit-per-second data rates. The National Storage Laboratory was officially launched on 27 May 1992.
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Wing Classification in the Virtual Research Center
NASA Technical Reports Server (NTRS)
Campbell, William H.
1999-01-01
The Virtual Research Center (VRC) is a Web site that hosts a database of documents organized to allow teams of scientists and engineers to store and maintain documents. A number of other workgroup-related capabilities are provided. My tasks as a NASA/ASEE Summer Faculty Fellow included developing a scheme for classifying the workgroups using the VRC using the various Divisions within NASA Enterprises. To this end I developed a plan to use several CGI Perl scripts to gather classification information from the leaders of the workgroups, and to display all the workgroups within a specified classification. I designed, implemented, and partially tested scripts which can be used to do the classification. I was also asked to consider directions for future development of the VRC. I think that the VRC can use XML to advantage. XML is a markup language with designer tags that can be used to build meaning into documents. An investigation as to how CORBA, an object-oriented object request broker included with JDK 1.2, might be used also seems justified.
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NASA Astrophysics Data System (ADS)
Mandal, Gour Chandra; Mukherjee, Rahul; Das, Binoy; Patra, Ardhendu Sekhar
2018-03-01
An innovative low cost reflective semiconductor amplifier (RSOA) based bidirectional Triple-play services (TPS) using wavelength division multiplexed radio on free-space-optics passive optical network (WDM-RoFSO-PON) is proposed and experimentally demonstrated to transmit data, voice and video services simultaneously. In this paper, the TPS (10 Gb/s data/voice and 1.49 Gb/s HDTV signal) are successfully transmitted over a 500 m free-space link in downstream and RSOA is utilized at the receiving site to broadcast 1.25 Gb/s data/voice signal over same free-space link in upstream by reusing the carrier, that makes the system cost-effective. High receiver sensitivity and signal-to-noise ratio (SNR), low bit-error-rate (BER) and low error vector magnitude (EVM), and excellent eye-diagrams in our proposed network build the system more reliable and stable with acceptable performance. Therefore, proposed WDM-RoFSO-PON could be the viable solution for future ubiquitous multiservice wireless network in the scenario of TPS.
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Frouin, Eléonore; Bes, Méline; Ollivier, Bernard; Quéméneur, Marianne; Postec, Anne; Debroas, Didier; Armougom, Fabrice; Erauso, Gaël
2018-01-01
The Bay of Prony, South of New Caledonia, represents a unique serpentinite-hosted hydrothermal field due to its coastal situation. It harbors both submarine and intertidal active sites, discharging hydrogen- and methane-rich alkaline fluids of low salinity and mild temperature through porous carbonate edifices. In this study, we have extensively investigated the bacterial and archaeal communities inhabiting the hydrothermal chimneys from one intertidal and three submarine sites by 16S rRNA gene amplicon sequencing. We show that the bacterial community of the intertidal site is clearly distinct from that of the submarine sites with species distribution patterns driven by only a few abundant populations, affiliated to the Chloroflexi and Proteobacteria phyla. In contrast, the distribution of archaeal taxa seems less site-dependent, as exemplified by the co-occurrence, in both submarine and intertidal sites, of two dominant phylotypes of Methanosarcinales previously thought to be restricted to serpentinizing systems, either marine (Lost City Hydrothermal Field) or terrestrial (The Cedars ultrabasic springs). Over 70% of the phylotypes were rare and included, among others, all those affiliated to candidate divisions. We finally compared the distribution of bacterial and archaeal phylotypes of Prony Hydrothermal Field with those of five previously studied serpentinizing systems of geographically distant sites. Although sensu stricto no core microbial community was identified, a few uncultivated lineages, notably within the archaeal order Methanosarcinales and the bacterial class Dehalococcoidia (the candidate division MSBL5) were exclusively found in a few serpentinizing systems while other operational taxonomic units belonging to the orders Clostridiales, Thermoanaerobacterales , or the genus Hydrogenophaga , were abundantly distributed in several sites. These lineages may represent taxonomic signatures of serpentinizing ecosystems. These findings extend our current knowledge of the microbial diversity inhabiting serpentinizing systems and their biogeography.
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Cell lineages of the embryo of the nematode Caenorhabditis elegans.
Deppe, U; Schierenberg, E; Cole, T; Krieg, C; Schmitt, D; Yoder, B; von Ehrenstein, G
1978-01-01
Embryogenesis of the free-living soil nematode Caenorhabditis elegans produces a juvenile having about 550 cells at hatching. We have determined the lineages of 182 cells by tracing the divisions of individual cells in living embryos. An invariant pattern of cleavage divisions of the egg generates a set of stem cells. These stem cells are the founders of six stem cell lineages. Each lineage has its own clock--i.e., an autonomous rhythm of synchronous cell divisions. The rhythms are maintained in spite of extensive cellular rearrangement. The rate and the orientation of the cell divisions of the cell lineages are essentially invariant among individuals. Thus, the destiny of cells seems to depend primarily on their lineage history. The anterior position of the site of origin of the stem cells in the egg relates to the rate of the cell cycle clock, suggesting intracellular preprogramming of the uncleaved egg. We used a technique that allows normal embryogenesis, from the fertilized egg to hatching, outside the parent under a cover glass. Embryogenesis was followed microscopically with Nomarski interference optics and high-resolution video recording.
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NASA Astrophysics Data System (ADS)
Garg, Amit Kumar; Madavi, Amresh Ashok; Janyani, Vijay
2017-02-01
A flexible hybrid wavelength division multiplexing-time division multiplexing passive optical network architecture that allows dual rate signals to be sent at 1 and 10 Gbps to each optical networking unit depending upon the traffic load is proposed. The proposed design allows dynamic wavelength allocation with pay-as-you-grow deployment capability. This architecture is capable of providing up to 40 Gbps of equal data rates to all optical distribution networks (ODNs) and up to 70 Gbps of a asymmetrical data rate to the specific ODN. The proposed design handles broadcasting capability with simultaneous point-to-point transmission, which further reduces energy consumption. In this architecture, each module sends a wavelength to each ODN, thus making the architecture fully flexible; this flexibility allows network providers to use only required OLT components and switch off others. The design is also reliable to any module or TRx failure and provides services without any service disruption. Dynamic wavelength allocation and pay-as-you-grow deployment support network extensibility and bandwidth scalability to handle future generation access networks.
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Brewster, Melanie E
2017-01-02
Recent studies have begun to attend to distribution of household labor within same-gender couples compared to heterosexual couples, yet much of the available research with lesbian couples has attempted to superimpose division of household labor frameworks developed with heterosexual couples (e.g., gender role socialization, exchange bargaining theories) to fit the experiences of same-gender couples. Using two academic search databases, the present article provides a systematic review of the available 28 peer-reviewed articles published from 2000-2015 about lesbian partnerships and household labor divisions. Results indicate that lesbian couples engage in a more equal distribution of household labor than heterosexual couples, and that lesbian women often opt to eschew traditional gendered divisions of chores in favor of other factors such as quality of task or ability. The systematic review uncovered notable constraints in the demography of participants (e.g., race, socioeconomic status, geographic location) across studies. Strategies for deepening the depth and breadth of this line of work for future researchers, and implications for relationship satisfaction are also discussed.
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Mass storage system experiences and future needs at the National Center for Atmospheric Research
NASA Technical Reports Server (NTRS)
Olear, Bernard T.
1991-01-01
A summary and viewgraphs of a discussion presented at the National Space Science Data Center (NSSDC) Mass Storage Workshop is included. Some of the experiences of the Scientific Computing Division at the National Center for Atmospheric Research (NCAR) dealing the the 'data problem' are discussed. A brief history and a development of some basic mass storage system (MSS) principles are given. An attempt is made to show how these principles apply to the integration of various components into NCAR's MSS. Future MSS needs for future computing environments is discussed.
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DOE Office of Scientific and Technical Information (OSTI.GOV)
INSTRUMENTATION DIVISION STAFF
To develop state-of-the-art instrumentation required for experimental research programs at BNL, and to maintain the expertise and facilities in specialized high technology areas essential for this work. Development of facilities is motivated by present BNL research programs and anticipated future directions of BNL research. The Division's research efforts also have a significant impact on programs throughout the world that rely on state-of-the-art radiation detectors and readout electronics. Our staff scientists are encouraged to: Become involved in challenging problems in collaborations with other scientists; Offer unique expertise in solving problems; and Develop new devices and instruments when not commercially available. Scientistsmore » from other BNL Departments are encouraged to bring problems and ideas directly to the Division staff members with the appropriate expertise. Division staff is encouraged to become involved with research problems in other Departments to advance the application of new ideas in instrumentation. The Division Head integrates these efforts when they evolve into larger projects, within available staff and budget resources, and defines the priorities and direction with concurrence of appropriate Laboratory program leaders. The Division Head also ensures that these efforts are accompanied by strict adherence to all ES and H regulatory mandates and policies of the Laboratory. The responsibility for safety and environmental protection is integrated with supervision of particular facilities and conduct of operations.« less
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Central Federal Lands Division data collection packages : final report.
DOT National Transportation Integrated Search
2011-03-31
The purpose of this research study was to develop a proof of concept, prototype electronic data-collection and reporting system to facilitate the completion of Emergency Relief for Federally Owned (ERFO) Roads Damage Site Reports (DSR). The system wo...
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PLUME-SCALER-EVALUATING LONG-TERM MONITORING WELL NETWORKS
EPA's Subsurface Protection and Remediation Division is developing a new computer application called PLUME-SCALER to evaluate long term monitoring well networks using typically available historical site water level data. PLUME-SCALER can be used to determine if there are enough ...
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Nitrogen and groundwater at Green Island restoration site
The Ground Water and Ecosystem Restoration Division (GWERD) of the USEPA investigates best management practices (BMP’s) and restoration techniques in aquatic ecosystems throughout the United States. Research on a) river restoration b) riparian buffer zones c) macrophytes, and d) ...
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Global Energy: Supply, Demand, Consequences, Opportunities (LBNL Summer Lecture Series)
Majumdar, Arun [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Environmental Energy Technologies Division; Univ. of California, Berkeley, CA (United States). Dept. of Materials Science and Engineering and Dept. of Mechanical Engineering
2018-05-04
Summer Lecture Series 2009: Arun Majumdar, Director of the Environmental Energy Technologies Division, discusses current and future projections of economic growth, population, and global energy demand and supply, and explores the implications of these trends for the environment.
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2014-04-30
CAPE CANAVERAL, Fla. – A technician vents off the gas from the propellant lines of NASA's Project Morpheus prototype lander after it completed a free-flight test at the north end of the Shuttle Landing Facility at NASA's Kennedy Space Center in Florida. The 98-second test began at 1:57 p.m. EDT with the Morpheus lander launching from the ground over a flame trench and ascending more than 800 feet at a peak speed of 36 mph. The vehicle, with its recently installed autonomous landing and hazard avoidance technology, or ALHAT, sensors surveyed the hazard field to determine safe landing sites. Morpheus then flew forward and downward covering approximately 1300 feet while performing a 78-foot divert to simulate a hazard avoidance maneuver. The lander descended and landed on a dedicated pad inside the ALHAT hazard field. Project Morpheus tests NASA’s ALHAT and an engine that runs on liquid oxygen and methane, which are green propellants. These new capabilities could be used in future efforts to deliver cargo to planetary surfaces. The landing facility provides the lander with the kind of field necessary for realistic testing, complete with rocks, craters and hazards to avoid. Morpheus’ ALHAT payload allows it to navigate to clear landing sites amidst rocks, craters and other hazards during its descent. Project Morpheus is being managed under the Advanced Exploration Systems, or AES, Division in NASA’s Human Exploration and Operations Mission Directorate. The efforts in AES pioneer new approaches for rapidly developing prototype systems, demonstrating key capabilities and validating operational concepts for future human missions beyond Earth orbit. For more information on Project Morpheus, visit http://morpheuslander.jsc.nasa.gov/. Photo credit: NASA/Kim Shiflett
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2014-04-30
CAPE CANAVERAL, Fla. – Technicians vent off the gas from the propellant lines of NASA's Project Morpheus prototype lander after it completed a free-flight test at the north end of the Shuttle Landing Facility at NASA's Kennedy Space Center in Florida. The 98-second test began at 1:57 p.m. EDT with the Morpheus lander launching from the ground over a flame trench and ascending more than 800 feet at a peak speed of 36 mph. The vehicle, with its recently installed autonomous landing and hazard avoidance technology, or ALHAT, sensors surveyed the hazard field to determine safe landing sites. Morpheus then flew forward and downward covering approximately 1300 feet while performing a 78-foot divert to simulate a hazard avoidance maneuver. The lander descended and landed on a dedicated pad inside the ALHAT hazard field. Project Morpheus tests NASA’s ALHAT and an engine that runs on liquid oxygen and methane, which are green propellants. These new capabilities could be used in future efforts to deliver cargo to planetary surfaces. The landing facility provides the lander with the kind of field necessary for realistic testing, complete with rocks, craters and hazards to avoid. Morpheus’ ALHAT payload allows it to navigate to clear landing sites amidst rocks, craters and other hazards during its descent. Project Morpheus is being managed under the Advanced Exploration Systems, or AES, Division in NASA’s Human Exploration and Operations Mission Directorate. The efforts in AES pioneer new approaches for rapidly developing prototype systems, demonstrating key capabilities and validating operational concepts for future human missions beyond Earth orbit. For more information on Project Morpheus, visit http://morpheuslander.jsc.nasa.gov/. Photo credit: NASA/Kim Shiflett
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2014-04-30
CAPE CANAVERAL, Fla. – A technician vents off the gas from the propellant lines of NASA's Project Morpheus prototype lander after it landed from a free-flight test at the north end of the Shuttle Landing Facility at NASA's Kennedy Space Center in Florida. The 98-second test began at 1:57 p.m. EDT with the Morpheus lander launching from the ground over a flame trench and ascending more than 800 feet at a peak speed of 36 mph. The vehicle, with its recently installed autonomous landing and hazard avoidance technology, or ALHAT, sensors surveyed the hazard field to determine safe landing sites. Morpheus then flew forward and downward covering approximately 1300 feet while performing a 78-foot divert to simulate a hazard avoidance maneuver. The lander descended and landed on a dedicated pad inside the ALHAT hazard field. Project Morpheus tests NASA’s ALHAT and an engine that runs on liquid oxygen and methane, which are green propellants. These new capabilities could be used in future efforts to deliver cargo to planetary surfaces. The landing facility provides the lander with the kind of field necessary for realistic testing, complete with rocks, craters and hazards to avoid. Morpheus’ ALHAT payload allows it to navigate to clear landing sites amidst rocks, craters and other hazards during its descent. Project Morpheus is being managed under the Advanced Exploration Systems, or AES, Division in NASA’s Human Exploration and Operations Mission Directorate. The efforts in AES pioneer new approaches for rapidly developing prototype systems, demonstrating key capabilities and validating operational concepts for future human missions beyond Earth orbit. For more information on Project Morpheus, visit http://morpheuslander.jsc.nasa.gov/. Photo credit: NASA/Kim Shiflett
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Reflections on the Galileoscope Program: Goals, Challenges, Achievements, and Future Directions
NASA Astrophysics Data System (ADS)
Pompea, Stephen M.; Fienberg, R. T.; Arion, D. N.
2010-01-01
The value of an inexpensive telescope that could be constructed and used at night became clear in the planning process for the International Year of Astronomy 2009. In fact, it became a national and international priority to develop such a telescope. Thus was born the Galileoscope project, as it later became known. We tested nearly every department store telescope available and finding them wanting in some major aspect, project members developed and tested a series of prototypes of refracting telescope kits. A key to the project is that the telescope is professionally designed and engineered with its design informed by extensive usability testing to ensure that it can be used easily by people of all ages. The eyepiece has excellent eye relief, for example, so that one can observe with glasses. The primary image quality requirement was that the telescope be good enough to see the rings of Saturn, as well as the Galilean satellites of Jupiter, with a field of view large enough to view the entire Pleiades. The Galileoscope is an ideal telescope to reproduce the observations of Galileo, from any place bright city or dark rural site. For the science classroom, we have developed well-tested educational materials on observing with the Galileoscope and teaching optics with it, available in pdf format on the Web site www. galileoscope.org. The educational materials are standards-based and appropriate for high school and beginning-level physics classes. Some of the key project decisions will be described and the future directions of the project will be described. This work was supported by a grant from the National Science Foundation Astronomy Division. NOAO is operated by the Association of Universities for Research in Astronomy (AURA), Inc. under cooperative agreement with the National Science Foundation.
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2014-04-30
CAPE CANAVERAL, Fla. – NASA's Project Morpheus prototype lander touches down on the autonomous landing and hazard avoidance technology, or ALHAT, field after lifting off on a free-flight test from a new launch pad at the north end of the Shuttle Landing Facility at NASA's Kennedy Space Center in Florida. The 98-second test began at 1:57 p.m. EDT with the Morpheus lander launching from the ground over a flame trench and ascending more than 800 feet at a peak speed of 36 mph. The vehicle, with its recently installed ALHAT sensors, surveyed the hazard field to determine safe landing sites. Morpheus then flew forward and downward covering approximately 1300 feet while performing a 78-foot divert to simulate a hazard avoidance maneuver. The lander descended and landed on a dedicated pad inside the ALHAT hazard field. Project Morpheus tests NASA’s ALHAT and an engine that runs on liquid oxygen and methane, which are green propellants. These new capabilities could be used in future efforts to deliver cargo to planetary surfaces. The landing facility provides the lander with the kind of field necessary for realistic testing, complete with rocks, craters and hazards to avoid. Morpheus’ ALHAT payload allows it to navigate to clear landing sites amidst rocks, craters and other hazards during its descent. Project Morpheus is being managed under the Advanced Exploration Systems, or AES, Division in NASA’s Human Exploration and Operations Mission Directorate. The efforts in AES pioneer new approaches for rapidly developing prototype systems, demonstrating key capabilities and validating operational concepts for future human missions beyond Earth orbit. For more information on Project Morpheus, visit http://morpheuslander.jsc.nasa.gov/. Photo credit: NASA/Kim Shiflett
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2014-04-30
CAPE CANAVERAL, Fla. – Engineers and technicians check NASA's Project Morpheus prototype lander after it touched down on a dedicated landing pad inside the autonomous landing and hazard avoidance technology, or ALHAT, hazard field at the north end of the Shuttle Landing Facility at NASA's Kennedy Space Center in Florida. Morpheus launched on a free-flight test from a new launch pad at the north end of the landing facility. The 98-second test began at 1:57 p.m. EDT with the Morpheus lander launching from the ground over a flame trench and ascending more than 800 feet at a peak speed of 36 mph. The vehicle, with its recently installed ALHAT sensors, surveyed the hazard field to determine safe landing sites. Morpheus then flew forward and downward covering approximately 1300 feet while performing a 78-foot divert to simulate a hazard avoidance maneuver before landing on the dedicated pad inside the ALHAT hazard field. Project Morpheus tests NASA’s ALHAT and an engine that runs on liquid oxygen and methane, which are green propellants. These new capabilities could be used in future efforts to deliver cargo to planetary surfaces. The landing facility provides the lander with the kind of field necessary for realistic testing, complete with rocks, craters and hazards to avoid. Morpheus’ ALHAT payload allows it to navigate to clear landing sites amidst rocks, craters and other hazards during its descent. Project Morpheus is being managed under the Advanced Exploration Systems, or AES, Division in NASA’s Human Exploration and Operations Mission Directorate. The efforts in AES pioneer new approaches for rapidly developing prototype systems, demonstrating key capabilities and validating operational concepts for future human missions beyond Earth orbit. For more information on Project Morpheus, visit http://morpheuslander.jsc.nasa.gov/. Photo credit: NASA/Kim Shiflett
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2014-04-30
CAPE CANAVERAL, Fla. – NASA's Project Morpheus prototype lander touches down on the autonomous landing and hazard avoidance technology, or ALHAT, field after lifting off on a free-flight test from a new launch pad at the north end of the Shuttle Landing Facility at NASA's Kennedy Space Center in Florida. The 98-second test began at 1:57 p.m. EDT with the Morpheus lander launching from the ground over a flame trench and ascending more than 800 feet at a peak speed of 36 mph. The vehicle, with its recently installed ALHAT sensors, surveyed the hazard field to determine safe landing sites. Morpheus then flew forward and downward covering approximately 1300 feet while performing a 78-foot divert to simulate a hazard avoidance maneuver. The lander descended and landed on a dedicated pad inside the ALHAT hazard field. Project Morpheus tests NASA’s ALHAT and an engine that runs on liquid oxygen and methane, which are green propellants. These new capabilities could be used in future efforts to deliver cargo to planetary surfaces. The landing facility provides the lander with the kind of field necessary for realistic testing, complete with rocks, craters and hazards to avoid. Morpheus’ ALHAT payload allows it to navigate to clear landing sites amidst rocks, craters and other hazards during its descent. Project Morpheus is being managed under the Advanced Exploration Systems, or AES, Division in NASA’s Human Exploration and Operations Mission Directorate. The efforts in AES pioneer new approaches for rapidly developing prototype systems, demonstrating key capabilities and validating operational concepts for future human missions beyond Earth orbit. For more information on Project Morpheus, visit http://morpheuslander.jsc.nasa.gov/. Photo credit: NASA/Frankie Martin
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DOE Office of Scientific and Technical Information (OSTI.GOV)
Yard, C.R.
1997-02-01
Through the cooperative efforts of the State of Tennessee and the Department of Energy, privatization of the first federal facility on the Oak Ridge Reservation has become a reality. One section of the facility has been transferred to private industry while the other portion of the facility remains in control of the government`s prime contractor. Due to this unusual arrangement, there are significant issues to be dealt with. This paper will describe the issues and concerns expressed by the participants in the process. The State of Tennessee`s efforts are primarily conducted by two Divisions of the Department of Environment andmore » Conservation. These two Divisions (Radiological Health and DOE-Oversight) share the responsibility of assuring that the privatization effort is properly implemented. This shared responsibility is divided along distinct lines by the Divisions respective regulatory and nonregulatory functions. DOE responsibilities during transfer are delineated in the Federal Facilities Agreement (FFA) section XLIII. Property Transfer. The FFA states (in part) that {open_quotes}the DOE shall include notice of this agreement in any document transferring ownership or operation of the site to any subsequent owner and/or operator of any portion of the site and shall notify EPA and TDEC of any such sale or Transfer.{close_quotes} The FFA continues by stating that {open_quotes}No change in ownership of the site or any portionthereof or notice pursuant to Section 120 (h) (3) (B) of CERCLA, 42 U.S.C. {delta} 9620 (h) (3) (B), shall relieve the DOE of its obligation to perform pursuant to this agreement. No change of ownership of the site or any portion thereof shall be consummated by the DOE without provision for continued maintenance of any containment system, treatment system, or other response action(s) installed or implemented pursuant to this Agreement. This provision does not relieve the DOE of its obligation under 40 C.F.R. Part 270.{close_quotes}« less
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Bacterial cytoskeleton and implications for new antibiotic targets.
Wang, Huan; Xie, Longxiang; Luo, Hongping; Xie, Jianping
2016-01-01
Traditionally eukaryotes exclusive cytoskeleton has been found in bacteria and other prokaryotes. FtsZ, MreB and CreS are bacterial counterpart of eukaryotic tubulin, actin filaments and intermediate filaments, respectively. FtsZ can assemble to a Z-ring at the cell division site, regulate bacterial cell division; MreB can form helical structure, and involve in maintaining cell shape, regulating chromosome segregation; CreS, found in Caulobacter crescentus (C. crescentus), can form curve or helical filaments in intracellular membrane. CreS is crucial for cell morphology maintenance. There are also some prokaryotic unique cytoskeleton components playing crucial roles in cell division, chromosome segregation and cell morphology. The cytoskeleton components of Mycobacterium tuberculosis (M. tuberculosis), together with their dynamics during exposure to antibiotics are summarized in this article to provide insights into the unique organization of this formidable pathogen and druggable targets for new antibiotics.
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Impact of drought on the temporal dynamics of wood formation in Pinus sylvestris
GRUBER, ANDREAS; STROBL, STEFAN; VEIT, BARBARA; OBERHUBER, WALTER
2011-01-01
Summary We determined the temporal dynamics of cambial activity and xylem cell differentiation of Scots pine (Pinus sylvestris L.) within a dry inner Alpine valley (750 m asl, Tyrol, Austria), where radial growth is strongly limited by drought in spring. Repeated micro-sampling of the developing tree ring of mature trees was carried out during 2 contrasting years at two study plots that differ in soil water availability (xeric and dry-mesic site). In 2007, when air temperature at the beginning of the growing season in April exceeded the long-term mean by 6.4 °C, cambial cell division started in early April at both study plots. A delayed onset of cambial activity of c. 2 wk was found in 2008, when average climate conditions prevailed in spring, indicating that resumption of cambial cell division after winter dormancy is temperature-controlled. Cambial cell division consistently ended about the end of June/early July in both study years. Radial enlargement of tracheids started almost 3 wk earlier in 2007 compared with 2008 at both study plots. At the xeric site, the maximum rate of tracheid production in 2007 and 2008 was reached in early and mid-May, respectively, and c. 2 wk later, at the dry-mesic site. Since in both study years, more favorable growing conditions (i.e., an increase in soil water content) were recorded during summer, we suggest a strong sink competition for carbohydrates to mycorrhizal root and shoot growth. Wood formation stopped c. 4 wk earlier at the xeric compared with the dry-mesic site in both years, indicating a strong influence of drought stress on cell differentiation. This is supported by radial widths of earlywood cells, which were found to be significantly narrower at the xeric than at the dry-mesic site (P < 0.05). Repeated cellular analyses during the two growing seasons revealed that, although spatial variability in the dynamics and duration of cell differentiation processes in Pinus sylvestris exposed to drought is strongly influenced by water availability, the onset of cambial activity and cell differentiation is controlled by temperature. PMID:20197285
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Impact of drought on the temporal dynamics of wood formation in Pinus sylvestris.
Gruber, Andreas; Strobl, Stefan; Veit, Barbara; Oberhuber, Walter
2010-04-01
We determined the temporal dynamics of cambial activity and xylem cell differentiation of Scots pine (Pinus sylvestris L.) within a dry inner Alpine valley (750 m a.s.l., Tyrol, Austria), where radial growth is strongly limited by drought in spring. Repeated micro-sampling of the developing tree ring of mature trees was carried out during two contrasting years at two study plots that differ in soil water availability (xeric and dry-mesic sites). In 2007, when air temperature at the beginning of the growing season in April exceeded the long-term mean by 6.4 degrees C, cambial cell division started in early April at both study plots. A delayed onset of cambial activity of c. 2 weeks was found in 2008, when average climate conditions prevailed in spring, indicating that resumption of cambial cell division after winter dormancy is temperature controlled. Cambial cell division consistently ended about the end of June/early July in both study years. Radial enlargement of tracheids started almost 3 weeks earlier in 2007 compared with 2008 at both study plots. At the xeric site, the maximum rate of tracheid production in 2007 and 2008 was reached in early and mid-May, respectively, and c. 2 weeks later at the dry-mesic site. Since in both study years more favorable growing conditions (i.e., an increase in soil water content) were recorded during summer, we suggest a strong sink competition for carbohydrates to mycorrhizal root and shoot growth. Wood formation stopped c. 4 weeks earlier at the xeric compared with the dry-mesic site in both years, indicating a strong influence of drought stress on cell differentiation. This is supported by radial widths of earlywood cells, which were found to be significantly narrower at the xeric than at the dry-mesic site (P < 0.05). Repeated cellular analyses during the two growing seasons revealed that, although spatial variability in the dynamics and duration of cell differentiation processes in P. sylvestris exposed to drought is strongly influenced by water availability, the onset of cambial activity and cell differentiation is controlled by temperature.
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Sharpening the Tip of the Spear: Preparing Special Forces Detachment Commanders for the Future
2008-05-19
Persian Farsi, Korean, and Thai ) is 24 weeks long. Soldiers must successfully pass the Defense Language Proficiency Test (DLPT) by demonstrating...Brief (Fort Bragg, NC: 2007), 2. 29 real world GWOT project in coordination with one of the Theatre Special Operation Commands (TSOC).89 Weeks 13...Forces (JSOTF) with parallel major general Division commanders within theatre ? A second suggestion for future research begins with the question
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An Open Avionics and Software Architecture to Support Future NASA Exploration Missions
NASA Technical Reports Server (NTRS)
Schlesinger, Adam
2017-01-01
The presentation describes an avionics and software architecture that has been developed through NASAs Advanced Exploration Systems (AES) division. The architecture is open-source, highly reliable with fault tolerance, and utilizes standard capabilities and interfaces, which are scalable and customizable to support future exploration missions. Specific focus areas of discussion will include command and data handling, software, human interfaces, communication and wireless systems, and systems engineering and integration.
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Vendor management: a model for collaboration and quality improvement.
Friedman, M D; Bailit, M H; Michel, J O
1995-11-01
The Massachusetts Medicaid agency, also known as the Division of Medical Assistance, has developed a quality-driven approach for managing its managed care suppliers. Such an approach has, as its foundation, principles of continuous quality improvement (CQI). Suppliers participate in an annual process whereby CQI goals are negotiated between the division and its suppliers. The division then works with suppliers to achieve such goals. A cornerstone of the division's approach is the notion that data can highlight an unlimited number of opportunities for improvement and that pursuit of such opportunities will ultimately result in meaningful improvements in the health status of recipients who are served by the division. The agency's approach involves five key steps: 1) the development of contractual terms and purchasing specifications; 2) the identification of improvement priorities; 3) the negotiation of improvement goals; 4) efforts directed at meeting improvement goals and measurement of success; and 5) collaboration to achieve mutual objectives. Overall, suppliers report many benefits of collaborative participation in CQI activities with the division. Suppliers have enhanced their understanding of the importance of meeting the needs of the customer and have further accrued benefits resulting from discussions with managed care vendors throughout the site regarding benchmarking of efforts and CQI efforts. Conversely, suppliers are challenged by the need to balance and allocate resources to meet increasing demands, which are not always consistent, from various purchasers, including the division. The division has been challenged in the evolution of its contract management strategy by an uneven level of knowledge among managed care vendors regarding CQI; goal setting and measurement issues; the length of time and level of effort required to develop good relationships with suppliers; and the critical importance of comparable, valid, and timely submission of data. Over the last three years, the division has seen a dramatic increase in the responsiveness of managed care suppliers to meet its needs as a purchaser. Specifically, this has been expressed through supplier ability to meet mutually negotiated improvement goals. The division is also pleased that it is beginning to achieve some measurable improvements in outcomes of care.
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Gender Dynamics Predict Changes in Marital Love Among African American Couples
Stanik, Christine E.; McHale, Susan M.; Crouter, Ann C.
2013-01-01
This study examined the implications of gender attitudes and spouses’ divisions of household labor, time with children, and parental knowledge for their trajectories of love in a sample of 146 African American couples. Multilevel modeling in the context of an accelerated longitudinal design accommodated 3 annual waves of data. The results revealed that traditionality in husbands’ gender attitudes was linked to lower levels of love. Furthermore, divisions of household labor and parental knowledge moderated changes in love such that couples with more egalitarian divisions exhibited higher and more stable patterns of love, whereas more traditional couples exhibited significant declines in love over time. Finally, greater similarity between spouses’ time with their children was linked to higher levels of marital love. The authors highlight the implications of gender dynamics for marital harmony among African American couples and discuss ways that this work may be applied and extended in practice and future research. PMID:23956462
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The Environmental Photographic Interpretation Center (EPIC) is a field station of the Landscape Ecology Branch (LEB), Environmental Sciences Division - Las Vegas, Office of Research and Development EPIC provides remote sensing technical support to help the Agency achieve its mult...
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Federal Register 2010, 2011, 2012, 2013, 2014
2013-09-04
... Carolina. The workers are engaged in activities related to the production of mechanic's hand tool sets. The... production of mechanic's hand tool sets to a foreign country. Based on these findings, the Department is...
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77 FR 61432 - Proposal Review for Materials Research; Notice of Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2012-10-09
... NATIONAL SCIENCE FOUNDATION Proposal Review for Materials Research; Notice of Meeting In... Foundation announces the following meeting: Name: Site visit review of the Materials Research Science and... Director, Materials Research Science and Engineering Centers Program, Division of Materials Research, Room...
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COMPARISON OF PREDICTED AND OBSERVED PLUME TRENDS AT CONTAMINATED SITES
Over 45 natural attenuation treatability studies (TSs) were performed from 1993 to 1999 by Parsons Corporation (Parsons) for the Technology Transfer Division of the Air Force Center for Environmental Excellence (AFCEE/ERT) in conjunction with researchers from the US EPA - NRMRL. ...
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NANA Geothermal Assessment Program Final Report
DOE Office of Scientific and Technical Information (OSTI.GOV)
Jay Hermanson
2010-06-22
In 2008, NANA Regional Corporation (NRC) assessed geothermal energy potential in the NANA region for both heat and/or electricity production. The Geothermal Assessment Project (GAP) was a systematic process that looked at community resources and the community's capacity and desire to develop these resources. In October 2007, the US Department of Energy's Tribal Energy Program awarded grant DE-FG36-07GO17075 to NRC for the GAP studies. Two moderately remote sites in the NANA region were judged to have the most potential for geothermal development: (1) Granite Mountain, about 40 miles south of Buckland, and (2) the Division Hot Springs area in themore » Purcell Mountains, about 40 miles south of Shungnak and Kobuk. Data were collected on-site at Granite Mountain Hot Springs in September 2009, and at Division Hot Springs in April 2010. Although both target geothermal areas could be further investigated with a variety of exploration techniques such as a remote sensing study, a soil geochemical study, or ground-based geophysical surveys, it was recommended that on-site or direct heat use development options are more attractive at this time, rather than investigations aimed more at electric power generation.« less
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Interstate 73 economic impact analysis : a guide to the methodology and results, part 2.
DOT National Transportation Integrated Search
1994-01-01
The Transportation Planning Division of the Virginia Department of Transportation (VDOT) is currently considering seven corridors along which VDOT may build the future Interstate 73. The purpose of this technical assistance project is to estimate the...
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Communications and Intelligent Systems Division Overview
NASA Technical Reports Server (NTRS)
Emerson, Dawn
2017-01-01
This presentation provides an overview of the research and engineering work being performed in the competency fields of advanced communications and intelligent systems with emphasis on advanced technologies, architecture definition, and systems development for application in current and future aeronautics and space communications systems.
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7 CFR 27.39 - Issuance of classification records.
Code of Federal Regulations, 2014 CFR
2014-01-01
... REGULATIONS COTTON CLASSIFICATION UNDER COTTON FUTURES LEGISLATION Regulations Cotton Class Certificates § 27... practicable after the classification of cotton has been completed by the Cotton and Tobacco Programs, the Quality Assurance Division shall issue an electronic cotton classification record showing the results of...
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DOE Office of Scientific and Technical Information (OSTI.GOV)
NONE
1992-08-01
The US Department of Energy (DOE) proposes to conduct a program to characterize groundwater at the Nevada Test Site (NTS), Nye County, Nevada, in accordance with a 1987 DOE memorandum stating that all past, present, and future nuclear test sites would be treated as Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) sites (Memorandum from Bruce Green, Weapons Design and Testing Division, June 6, 1987). DOE has prepared an environmental assessment (DOE/EA-0532) to evaluate the environmental consequences associated with the proposed action, referred to as the Groundwater Characterization Project (GCP). This proposed action includes constructing access roads and drill pads,more » drilling and testing wells, and monitoring these wells for the purpose of characterizing groundwater at the NTS. Long-term monitoring and possible use of these wells in support of CERCLA, as amended by the Superfund Amendments and Reauthorization Act, is also proposed. The GCP includes measures to mitigate potential impacts on sensitive biological, cultural and historical resources, and to protect workers and the environment from exposure to any radioactive or mixed waste materials that may be encountered. DOE considers those mitigation measures related to sensitive biological, cultural and historic resources as essential to render the impacts of the proposed action not significant, and DOE has prepared a Mitigation Action Plan (MAP) that explains how such mitigations will be planned and implemented. Based on the analyses presented in the EA, DOE has determined that the proposed action is not a major Federal action significantly affecting the quality of the human environment, within the meaning of the National Environmental Policy Act of 1969 (NEPA). Therefore, preparation of an environmental impact statement is not required and the Department is issuing this FONSI.« less
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NEEMO 20: Science Training, Operations, and Tool Development
NASA Technical Reports Server (NTRS)
Graff, T.; Miller, M.; Rodriguez-Lanetty, M.; Chappell, S.; Naids, A.; Hood, A.; Coan, D.; Abell, P.; Reagan, M.; Janoiko, B.
2016-01-01
The 20th mission of the National Aeronautics and Space Administration (NASA) Extreme Environment Mission Operations (NEEMO) was a highly integrated evaluation of operational protocols and tools designed to enable future exploration beyond low-Earth orbit. NEEMO 20 was conducted from the Aquarius habitat off the coast of Key Largo, FL in July 2015. The habitat and its surroundings provide a convincing analog for space exploration. A crew of six (comprised of astronauts, engineers, and habitat technicians) lived and worked in and around the unique underwater laboratory over a mission duration of 14-days. Incorporated into NEEMO 20 was a diverse Science Team (ST) comprised of geoscientists from the Astromaterials Research and Exploration Science (ARES/XI) Division from the Johnson Space Center (JSC), as well as marine scientists from the Department of Biological Sciences at Florida International University (FIU). This team trained the crew on the science to be conducted, defined sampling techniques and operational procedures, and planned and coordinated the science focused Extra Vehicular Activities (EVAs). The primary science objectives of NEEMO 20 was to study planetary sampling techniques and tools in partial gravity environments under realistic mission communication time delays and operational pressures. To facilitate these objectives two types of science sites were employed 1) geoscience sites with available rocks and regolith for testing sampling procedures and tools and, 2) marine science sites dedicated to specific research focused on assessing the photosynthetic capability of corals and their genetic connectivity between deep and shallow reefs. These marine sites and associated research objectives included deployment of handheld instrumentation, context descriptions, imaging, and sampling; thus acted as a suitable proxy for planetary surface exploration activities. This abstract briefly summarizes the scientific training, scientific operations, and tool development conducted during NEEMO 20 with an emphasis on the primary lessons learned.
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Evapotranspiration Cover for the 92-Acre Area Retired Mixed Waste Pits:Interim CQA Report
DOE Office of Scientific and Technical Information (OSTI.GOV)
The Delphi Groupe, Inc., and J. A. Cesare and Associates, Inc.
This Interim Construction Quality Assurance (CQA) Report is for the 92-Acre Evapotranspiration Cover, Area 5 Waste Management Division (WMD) Retired Mixed Waste Pits, Nevada National Security Site, Nevada for the period of January 20, 2011 to May 12, 2011. This Interim Construction Quality Assurance (CQA) Report is for the 92-Acre Evapotranspiration Cover, Area 5 Waste Management Division (WMD) Retired Mixed Waste Pits, Nevada National Security Site, Nevada for the period of January 20, 2011 to May 12, 2011. Construction was approved by the Nevada Division of Environmental Protection (NDEP) under the Approval of Corrective Action Decision Document/Corrective Action Plan (CADD/CAP)more » for Corrective Action Unit (CAU) 111: Area 5 WMD Retired Mixed Waste Pits, Nevada National Security Site, Nevada, on January 6, 2011, pursuant to Subpart XII.8a of the Federal Facility Agreement and Consent Order. The project is located in Area 5 of the Radioactive Waste Management Complex (RWMC) at the Nevada National Security Site (NNSS), formerly known as the Nevada Test Site, located in southern Nevada, approximately 65 miles northwest of Las Vegas, Nevada, in Nye County. The project site, in Area 5, is located in a topographically closed basin approximately 14 additional miles north of Mercury Nevada, in the north-central part of Frenchman Flat. The Area 5 RWMS uses engineered shallow-land burial cells to dispose of packaged waste. The 92-Acre Area encompasses the southern portion of the Area 5 RWMS, which has been designated for the first final closure operations. This area contains 13 Greater Confinement Disposal (GCD) boreholes, 16 narrow trenches, and 9 broader pits. With the exception of two active pits (P03 and P06), all trenches and pits in the 92-Acre Area had operational covers approximately 2.4 meters thick, at a minimum, in most areas when this project began. The units within the 92-Acre Area are grouped into the following six informal categories based on physical location, waste types and regulatory requirements: (1) Pit 3 Mixed Waste Disposal Unit (MWDU); (2) Corrective Action Unit (CAU) 111; (3) CAU 207; (4) Low-level waste disposal units; (5) Asbestiform low-level waste disposal units; and (6) One transuranic (TRU) waste trench.« less
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Timely Endocytosis of Cytokinetic Enzymes Prevents Premature Spindle Breakage during Mitotic Exit
Onishi, Masayuki; Yeong, Foong May
2016-01-01
Cytokinesis requires the spatio-temporal coordination of membrane deposition and primary septum (PS) formation at the division site to drive acto-myosin ring (AMR) constriction. It has been demonstrated that AMR constriction invariably occurs only after the mitotic spindle disassembly. It has also been established that Chitin Synthase II (Chs2p) neck localization precedes mitotic spindle disassembly during mitotic exit. As AMR constriction depends upon PS formation, the question arises as to how chitin deposition is regulated so as to prevent premature AMR constriction and mitotic spindle breakage. In this study, we propose that cells regulate the coordination between spindle disassembly and AMR constriction via timely endocytosis of cytokinetic enzymes, Chs2p, Chs3p, and Fks1p. Inhibition of endocytosis leads to over accumulation of cytokinetic enzymes during mitotic exit, which accelerates the constriction of the AMR, and causes spindle breakage that eventually could contribute to monopolar spindle formation in the subsequent round of cell division. Intriguingly, the mitotic spindle breakage observed in endocytosis mutants can be rescued either by deleting or inhibiting the activities of, CHS2, CHS3 and FKS1, which are involved in septum formation. The findings from our study highlight the importance of timely endocytosis of cytokinetic enzymes at the division site in safeguarding mitotic spindle integrity during mitotic exit. PMID:27447488
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DOE Office of Scientific and Technical Information (OSTI.GOV)
Feurer, D A; Weaver, C L; Gallagher, K C
1980-01-01
The Rhode Island statutes vest in the Public Utility Commission and the Division of Public Utilities the exclusive power and authority to regulate public utility companies in that state. Both bodies have been established within the Department of Business Regulation but are independent of the Department's director and are not under his jurisdiction. The jurisdiction to regulate utilities is shared by the Commission and the Division. The Commission serves as a quasi-judicial tribunal with jurisdiction, powers, and duties to hold investigations and hearings involving rates, sufficiency and resonableness of facilities, gas, electric, water, and pipeline public utilities. The administrator, whomore » is chief executive officer of the Division, is responsible for exercising the jurisdiction, supervision, powers, and duties not specifically assigned to the Commission. By virtue of his office, the chairman of the Commission serves also as the administrator and he supervises and directs the execution of all laws relating to public utilities and carriers and all regulations and orders of the Commission governing the conduct and charges of public utilities. Public utility regulatory statutes, energy facility siting programs, and municipal franchising authority are examined to identify how they may impact on the ability of an organization, whether or not it be a regulated utility, to construct and operate an ICES.« less
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-08-03
.... Location: Toledo, Ohio. Job Titles and/or Job Duties: All employees who worked in any area. Period of..., Division of Compensation Analysis and Support, National Institute for Occupational Safety and Health, 4676...
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Planetary quarantine computer applications
NASA Technical Reports Server (NTRS)
Rafenstein, M.
1973-01-01
The computer programs are identified pertaining to planetary quarantine activities within the Project Engineering Division, both at the Air Force Eastern Test Range and on site at the Jet Propulsion Laboratory. A brief description of each program and program inputs are given and typical program outputs are shown.
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Search the Division of Finance site DOF State of Alaska Finance Home Content Area Accounting Charge Cards Administrative Manual Table of Contents Contains State of Alaska accounting/payroll policies and information clarifying accounting and payroll procedures. Policies are carried out through standard statewide procedures
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75 FR 9001 - Proposal Review Panel for Materials Research; Notice of Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2010-02-26
... NATIONAL SCIENCE FOUNDATION Proposal Review Panel for Materials Research; Notice of Meeting In... Foundation announces the following meeting: Name: Site visit review of the Materials Research Science and... Science and Engineering Centers Program, Division of Materials Research, Room 1065, National Science...
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78 FR 11903 - Proposal Review Panel for Materials Research; Notice of Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2013-02-20
... NATIONAL SCIENCE FOUNDATION Proposal Review Panel for Materials Research; Notice of Meeting In... Foundation announces the following meeting: Name: Site Visit review of the Materials Research Science and... Research Science and Engineering Centers Program, Division of Materials Research, Room 1065, National...
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77 FR 61433 - Proposal Review Panel for Materials Research; Notice of Meeting
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2012-10-09
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77 FR 56236 - Proposal Review Panel for Materials Research; Notice of Meeting
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2012-09-12
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California Commercial End-Use Survey - CEUS
Information Power Plants California Energy Maps DRECP Dockets Unit E-filing and Commenting Power Plant Licensing Cases Power Plant Projects Status Power Plants Public Adviser's Office Siting, Transmission, and Environmental Protection Division More Power Plant Information Renewables Clean Energy & Pollution Reduction
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77 FR 44683 - Notice of Investigation Regarding Termination of Certification
Federal Register 2010, 2011, 2012, 2013, 2014
2012-07-30
... Investigation Regarding Termination of Certification TA-W-80,308, Roseburg Forest Products, Composite Panel... Products, Composite Panel Division, Including On-Site Leased Workers of Robert Half, Russellville, SC. On... Assistance (TAA) applicable to workers and former workers of Roseburg Forest Products, Composite Panel...
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77 FR 6826 - Proposal Review Panel for Materials Research; Notice of Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2012-02-09
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77 FR 57162 - Proposal Review Panel for Materials Research; Notice of Meeting
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2012-09-17
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77 FR 14441 - Proposal Review Panel for Materials Research; Notice of Meeting
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2012-03-09
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75 FR 4876 - Proposal Review Panel for Materials Research; Notice of Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2010-01-29
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77 FR 57161 - Proposal Review Panel for Materials Research; Notice of Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2012-09-17
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78 FR 5505 - Proposal Review Panel for Materials Research; Notice of Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2013-01-25
... NATIONAL SCIENCE FOUNDATION Proposal Review Panel for Materials Research; Notice of Meeting In... Foundation announces the following meeting: Name: Site Visit review of the Materials Research Science and.... Charles Bouldin, Program Director, Materials Research Science and Engineering Centers Program, Division of...
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The Technology Transfer and Support Division of the USEPA, Office of Research and Development's (ORD) National Risk Management Research Laboratory has developed this handbook, in conjunction with the South Florida Water Management District (SFWMD), to document The Living Everglad...
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77 FR 14441 - Proposal Review Panel for Physics; Notice of Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2012-03-09
... NATIONAL SCIENCE FOUNDATION Proposal Review Panel for Physics; Notice of Meeting In accordance... announces the following meeting. Name: LIGO Annual Review Site Visit at Hanford Observatory for Physics...: Partially Closed. Contact Person: Thomas Carruthers, Program Director, Division of Physics, National Science...
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76 FR 66998 - Proposal Review Panel for Physics; Notice of Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2011-10-28
... NATIONAL SCIENCE FOUNDATION Proposal Review Panel for Physics; Notice of Meeting In accordance... announces the following meeting. Name: LIGO Annual Review Site Visit at Hanford Observatory for Physics...: Partially Closed. Contact Person: Thomas Carruthers, Program Director, Division of Physics, National Science...
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Oxidation of F-actin controls the terminal steps of cytokinesis
Frémont, Stéphane; Hammich, Hussein; Bai, Jian; Wioland, Hugo; Klinkert, Kerstin; Rocancourt, Murielle; Kikuti, Carlos; Stroebel, David; Romet-Lemonne, Guillaume; Pylypenko, Olena; Houdusse, Anne; Echard, Arnaud
2017-01-01
Cytokinetic abscission, the terminal step of cell division, crucially depends on the local constriction of ESCRT-III helices after cytoskeleton disassembly. While the microtubules of the intercellular bridge are cut by the ESCRT-associated enzyme Spastin, the mechanism that clears F-actin at the abscission site is unknown. Here we show that oxidation-mediated depolymerization of actin by the redox enzyme MICAL1 is key for ESCRT-III recruitment and successful abscission. MICAL1 is recruited to the abscission site by the Rab35 GTPase through a direct interaction with a flat three-helix domain found in MICAL1 C terminus. Mechanistically, in vitro assays on single actin filaments demonstrate that MICAL1 is activated by Rab35. Moreover, in our experimental conditions, MICAL1 does not act as a severing enzyme, as initially thought, but instead induces F-actin depolymerization from both ends. Our work reveals an unexpected role for oxidoreduction in triggering local actin depolymerization to control a fundamental step of cell division. PMID:28230050
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Bebel, Aleksandra; Karaca, Ezgi; Kumar, Banushree; Stark, W Marshall; Barabas, Orsolya
2016-01-01
Bacterial Xer site-specific recombinases play an essential genome maintenance role by unlinking chromosome multimers, but their mechanism of action has remained structurally uncharacterized. Here, we present two high-resolution structures of Helicobacter pylori XerH with its recombination site DNA difH, representing pre-cleavage and post-cleavage synaptic intermediates in the recombination pathway. The structures reveal that activation of DNA strand cleavage and rejoining involves large conformational changes and DNA bending, suggesting how interaction with the cell division protein FtsK may license recombination at the septum. Together with biochemical and in vivo analysis, our structures also reveal how a small sequence asymmetry in difH defines protein conformation in the synaptic complex and orchestrates the order of DNA strand exchanges. Our results provide insights into the catalytic mechanism of Xer recombination and a model for regulation of recombination activity during cell division. DOI: http://dx.doi.org/10.7554/eLife.19706.001 PMID:28009253
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Nonmedially assembled F-actin cables incorporate into the actomyosin ring in fission yeast
Huang, Junqi; Huang, Yinyi; Yu, Haochen; Subramanian, Dhivya; Padmanabhan, Anup; Thadani, Rahul; Tao, Yaqiong; Tang, Xie; Wedlich-Soldner, Roland
2012-01-01
In many eukaryotes, cytokinesis requires the assembly and constriction of an actomyosin-based contractile ring. Despite the central role of this ring in cytokinesis, the mechanism of F-actin assembly and accumulation in the ring is not fully understood. In this paper, we investigate the mechanism of F-actin assembly during cytokinesis in Schizosaccharomyces pombe using lifeact as a probe to monitor actin dynamics. Previous work has shown that F-actin in the actomyosin ring is assembled de novo at the division site. Surprisingly, we find that a significant fraction of F-actin in the ring was recruited from formin-Cdc12p nucleated long actin cables that were generated at multiple nonmedial locations and incorporated into the ring by a combination of myosin II and myosin V activities. Our results, together with findings in animal cells, suggest that de novo F-actin assembly at the division site and directed transport of F-actin cables assembled elsewhere can contribute to ring assembly. PMID:23185032
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Consolidated Site (CS) 022 Verification Survey at Former McClellan AFB, Sacramento, California
2015-03-31
currently valid OMB control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. 1. REPORT DATE (DD-MM-YYYY) 31 Mar 2015 2. REPORT TYPE...Consultative Letter 3. DATES COVERED (From – To) July 2014 – December 2014 4. TITLE AND SUBTITLE Consolidated Site (CS) 022 Verification Survey at...the U.S. Air Force Radioisotope Committee Secretariat (RICS), the U.S. Air Force School of Aerospace Medicine, Consultative Services Division
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Consolidated Site (CS) 024 Verification Survey at Former McClellan AFB, Sacramento, California
2015-03-31
currently valid OMB control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. 1. REPORT DATE (DD-MM-YYYY) 31 Mar 2015 2. REPORT TYPE...Consultative Letter 3. DATES COVERED (From – To) July 2014 – December 2014 4. TITLE AND SUBTITLE Consolidated Site (CS) 024 Verification Survey at...the U.S. Air Force Radioisotope Committee Secretariat (RICS), the U.S. Air Force School of Aerospace Medicine, Consultative Services Division
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Pereira-Sampaio, Marco A; Henry, Robert W; Favorito, Luciano A; Sampaio, Francisco J B
2012-06-01
To assess the intrarenal arteries injuries after cranial pole nephrectomy in a pig model to compare these findings with those in humans. Polyester resin was injected through the ureter and the renal artery to make three-dimensional casts of 61 pig kidneys. The cranial pole of the kidneys was sectioned at four different sites before the solidification of the resin, and the casts were examined for arterial damage. Section performed through the hilus (15 kidneys): The cranial division of the renal artery was sectioned in two (13.33%) cases, the ventral branch of the cranial division of the renal artery was sectioned in 13 (86.7%) cases, and the dorsal branch of the cranial division of the renal artery was sectioned in 11 (73.34%) cases. Section at 0.5 cm cranial to the hilus (16 kidneys): The cranial division of the renal artery was sectioned in 1 (6.25%) case, the ventral branch of the cranial division of the renal artery was sectioned in 14 (87.5%) cases, and the dorsal branch of the cranial division of the renal artery was sectioned in 13 (81.25%) cases. Section at 1.0 cm cranial to the hilus (15 kidneys): The ventral branch of the cranial division of the renal artery was sectioned in five (33.33%) cases, and the dorsal branch of the cranial division of the renal artery was injured in five (33.33%) cases. Section at 1.5 cm cranial to the hilus (15 kidneys): No lesions were found in the main arteries, only in the interlobular branches. As previously demonstrated in humans, sections at 1.0 cm or more cranially to the hilus in pigs also showed a significant decrease in damage to the major intrarenal arteries. Therefore, as regards arterial damage, the pig kidney is a useful model for partial nephrectomy in the cranial (upper) pole.
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Water for the Nation: An overview of the USGS Water Resources Division
,
1998-01-01
The Water Resources Division (WRD) of the U.S. Geological Survey (USGS) provides reliable, impartial, timely information needed to understand the Nation's water resources. WRD actively promotes the use of this information by decisionmakers to: * Minimize the loss of life and property as a result of water-related hazards such as floods, droughts, and land movement. * Effectively manage ground-water and surface-water resources for domestic, agricultural, commercial, industrial, recreational, and ecological uses. * Protect and enhance water resources for human health, aquatic health, and environmental quality. * Contribute to wise physical and economic development of the Nation's resources for the benefit of present and future generations.
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2008-04-18
CAPE CANAVERAL, Fla. -- During a break in presentations at NASA’s Future Forum in Miami, astronaut Steve Frick and former astronaut Carl Walz sign autographs. Frick served as commander of the STS-122 shuttle mission. Walz is now director of NASA’s Advanced Capabilities Division. The forum focused on how space exploration benefits Florida's economy. The event, which included presentations and panels, was held at the University of Miami's BankUnited Center. Among those participating were NASA Deputy Administrator Shana Dale, astronaut Carl Walz, director of the Advanced Capabilities Division in NASA's Exploration Systems Mission Directorate, and Russell Romanella, director, International Space Station and Spacecraft Processing. Photo credit: NASA/Kim Shiflett
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NASA Technical Reports Server (NTRS)
Berk, G.; Jean, P. N.; Rotholz, E.
1982-01-01
Several satellite uplink and downlink accessing schemes for customer premises service are compared. Four conceptual system designs are presented: satellite-routed frequency division multiple access (FDMA), satellite-switched time division multiple access (TDMA), processor-routed TDMA, and frequency-routed TDMA, operating in the 30/20 GHz band. The designs are compared on the basis of estimated satellite weight, system capacity, power consumption, and cost. The systems are analyzed for fixed multibeam coverage of the continental United States. Analysis shows that the system capacity is limited by the available satellite resources and by the terminal size and cost.
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ERIC Educational Resources Information Center
Blum, Debra E.
1995-01-01
A $1.75-billion contract giving one television network the rights to broadcast National Collegiate Athletic Association Division I men's basketball for eight years is greeted with nonchalance. Concerns focus on interinstitutional and interleague competition, the future of sports advertising, and how the revenues will be spent. (MSE)
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Malice in Wonderland: The Linguist's Future in the German Department
ERIC Educational Resources Information Center
Markey, T. L.
1977-01-01
Suggests a tripartite division of instructional duties in college language departments: (1) language instruction on intermediate and advanced levels, (2) tutorial instruction, and (3) interdisciplinary courses to curtail compartmentalization and encourage cultural comparison. Linguist and literary scholar need not be at odds. (CHK)
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Federal Register 2010, 2011, 2012, 2013, 2014
2013-08-01
... of Electronic Distribution of Advanced Reactor Correspondence AGENCY: Nuclear Regulatory Commission. ACTION: Implementation of electronic distribution of advanced reactor correspondence; issuance. SUMMARY... public that, in the future, publicly available correspondence originating from the Division of Advanced...
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17 CFR 171.28 - Participation by Commission staff.
Code of Federal Regulations, 2010 CFR
2010-04-01
... staff. 171.28 Section 171.28 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION..., Membership Denial and Registration Actions § 171.28 Participation by Commission staff. The Division of.... The Commission shall by order establish a supplementary briefing schedule for the Commission staff and...
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17 CFR 171.28 - Participation by Commission staff.
Code of Federal Regulations, 2012 CFR
2012-04-01
... staff. 171.28 Section 171.28 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION..., Membership Denial and Registration Actions § 171.28 Participation by Commission staff. The Division of.... The Commission shall by order establish a supplementary briefing schedule for the Commission staff and...
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17 CFR 171.28 - Participation by Commission staff.
Code of Federal Regulations, 2011 CFR
2011-04-01
... staff. 171.28 Section 171.28 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION..., Membership Denial and Registration Actions § 171.28 Participation by Commission staff. The Division of.... The Commission shall by order establish a supplementary briefing schedule for the Commission staff and...
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17 CFR 171.28 - Participation by Commission staff.
Code of Federal Regulations, 2013 CFR
2013-04-01
... staff. 171.28 Section 171.28 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION..., Membership Denial and Registration Actions § 171.28 Participation by Commission staff. The Division of.... The Commission shall by order establish a supplementary briefing schedule for the Commission staff and...
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Sixth Annual NASA Ames Space Science and Astrobiology Jamboree
NASA Technical Reports Server (NTRS)
Hollingsworth, Jeffery; Howell, Steve; Fonda, Mark; Dateo, Chris; Martinez, Christine M.
2018-01-01
Welcome to the Sixth Annual NASA Ames Research Center, Space Science and Astrobiology Jamboree at NASA Ames Research Center (ARC). The Space Science and Astrobiology Division consists of over 60 Civil Servants, with more than 120 Cooperative Agreement Research Scientists, Post-Doctoral Fellows, Science Support Contractors, Visiting Scientists, and many other Research Associates. Within the Division there is engagement in scientific investigations over a breadth of disciplines including Astrobiology, Astrophysics, Exobiology, Exoplanets, Planetary Systems Science, and many more. The Division's personnel support NASA spacecraft missions (current and planned), including SOFIA, K2, MSL, New Horizons, JWST, WFIRST, and others. Our top-notch science research staff is spread amongst three branches in five buildings at ARC. Naturally, it can thus be difficult to remain abreast of what fellow scientific researchers pursue actively, and then what may present and/or offer regarding inter-Branch, intra-Division future collaborative efforts. In organizing this annual jamboree, the goals are to offer a wholesome, one-venue opportunity to sense the active scientific research and spacecraft mission involvement within the Division; and to facilitate communication and collaboration amongst our research scientists. Annually, the Division honors one senior research scientist with a Pollack Lecture, and one early career research scientist with an Outstanding Early Career Space Scientist Lecture. For the Pollack Lecture, the honor is bestowed upon a senior researcher who has made significant contributions within any area of research aligned with space science and/or astrobiology. This year we are pleased to honor Linda Jahnke. With the Early Career Lecture, the honor is bestowed upon an early-career researcher who has substantially demonstrated great promise for significant contributions within space science, astrobiology, and/or, in support of spacecraft missions addressing such disciplines. This year we are pleased to honor Amanda Cook. We hope that you will make time to join us for the day in meeting fellow Division members, expanding knowledge of our activities, and creating new collaborations within the Space Science and Astrobiology Division.
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Abe, Yoshito; Fujisaki, Naoki; Miyoshi, Takanori; Watanabe, Noriko; Katayama, Tsutomu; Ueda, Tadashi
2016-01-01
DnaAcos, a mutant of the initiator DnaA, causes overinitiation of chromosome replication in Escherichia coli, resulting in inhibition of cell division. CedA was found to be a multi-copy suppressor which represses the dnaAcos inhibition of cell division. However, functional mechanism of CedA remains elusive except for previously indicated possibilities in binding to DNA and RNA polymerase. In this study, we searched for the specific sites of CedA in binding of DNA and RNA polymerase and in repression of cell division inhibition. First, DNA sequence to which CedA preferentially binds was determined. Next, the several residues and β4 region in CedA C-terminal domain was suggested to specifically interact with the DNA. Moreover, we found that the flexible N-terminal region was required for tight binding to longer DNA as well as interaction with RNA polymerase. Based on these results, several cedA mutants were examined in ability for repressing dnaAcos cell division inhibition. We found that the N-terminal region was dispensable and that Glu32 in the C-terminal domain was required for the repression. These results suggest that CedA has multiple roles and residues with different functions are positioned in the two regions. PMID:26400504
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TDM1 Regulation Determines the Number of Meiotic Divisions
Cifuentes, Marta; Jolivet, Sylvie; Cromer, Laurence; Harashima, Hirofumi; Bulankova, Petra; Renne, Charlotte; Crismani, Wayne; Nomura, Yuko; Nakagami, Hirofumi; Sugimoto, Keiko; Schnittger, Arp; Riha, Karel; Mercier, Raphael
2016-01-01
Cell cycle control must be modified at meiosis to allow two divisions to follow a single round of DNA replication, resulting in ploidy reduction. The mechanisms that ensure meiosis termination at the end of the second and not at the end of first division are poorly understood. We show here that Arabidopsis thaliana TDM1, which has been previously shown to be essential for meiotic termination, interacts directly with the Anaphase-Promoting Complex. Further, mutations in TDM1 in a conserved putative Cyclin-Dependant Kinase (CDK) phosphorylation site (T16-P17) dominantly provoked premature meiosis termination after the first division, and the production of diploid spores and gametes. The CDKA;1-CYCA1.2/TAM complex, which is required to prevent premature meiotic exit, phosphorylated TDM1 at T16 in vitro. Finally, while CYCA1;2/TAM was previously shown to be expressed only at meiosis I, TDM1 is present throughout meiosis. These data, together with epistasis analysis, lead us to propose that TDM1 is an APC/C component whose function is to ensure meiosis termination at the end of meiosis II, and whose activity is inhibited at meiosis I by CDKA;1-TAM-mediated phosphorylation to prevent premature meiotic exit. This provides a molecular mechanism for the differential decision of performing an additional round of division, or not, at the end of meiosis I and II, respectively. PMID:26871453
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Multiple access techniques and spectrum utilization of the GLOBALSTAR mobile satellite system
NASA Astrophysics Data System (ADS)
Louie, Ming; Cohen, Michel; Rouffet, Denis; Gilhousen, Klein S.
The GLOBALSTAR System is a Low Earth Orbit (LEO) satellite-based mobile communications system that is interoperable with the current and future Public Land Mobile Network (PLMN). The GLOBALSTAR System concept is based upon technological advancement in two key areas: (1) the advancement in LEO satellite technology; (2) the advancement in cellular telephone technology, including the commercial applications of Code Division Multiple Access (CDMA) technologies, and of the most recent progress in Time Division Multiple Access technologies. The GLOBALSTAR System uses elements of CDMA, Frequency Division Multiple Access (FDMA), and Time Division Multiple Access (TDMA) technology, combining with satellite Multiple Beam Antenna (MBA) technology, to arrive at one of the most efficient modulation and multiple access system ever proposed for a satellite communications system. The technology used in GLOBALSTAR exploits the following techniques in obtaining high spectral efficiency and affordable cost per channel, with minimum coordination among different systems: power control, in open and closed loops, voice activation, spot beam satellite antenna for frequency reuse, weighted satellite antenna gain, multiple satellite coverage, and handoff between satellites. The GLOBALSTAR system design will use the following frequency bands: 1610-1626.5 MHz for up-link and 2483.5-2500 MHz for down-link.
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Hanford Works monthly report, December 1950
DOE Office of Scientific and Technical Information (OSTI.GOV)
Prout, G.R.
1951-01-22
This is a progress report of the production reactors on the Hanford Reservation for the month of December 1950. This report takes each division (e.g., manufacturing, medical, accounting, occupational safety, security, reactor operations, etc.) of the site and summarizes its accomplishments and employee relations for that month.