Sample records for future prospective studies

  1. The future is now: prospective temporal self-appraisals among defensive pessimists and optimists.

    PubMed

    Sanna, Lawrence J; Chang, Edward C; Carter, Seth E; Small, Eulena M

    2006-06-01

    Three studies found that prospective temporal self-appraisals can be part of defensive pessimists' strategy; they felt closer to equally distant negative than positive futures. In Study 1, defensive pessimists felt closer to future failures and reported more negative affect than those considering success. In Study 2, when manipulated negative futures were close, defensive pessimists felt bad and performed well; results suggested that viewing negative futures as close may be part of their natural strategy. Study 3 found that prospective self-appraisals influenced performances through felt preparation. Optimists did not use prospective self-appraisals (Study 1) and their performances were unaffected by manipulated temporal distance (Studies 2 and 3). Discussion centers on prospective self-appraisals and multiple strategies of defensive pessimists.

  2. Depression and prospection.

    PubMed

    Roepke, Ann Marie; Seligman, Martin E P

    2016-03-01

    Prospection, the mental representation of possible futures, is usually adaptive. When it goes awry, however, it disrupts emotion and motivation. A negative view of the future is typically seen as one symptom of depression, but we suggest that such negative prospection is the core causal element of depression. Here, we describe the empirical evidence supporting this framework, and we explore the implications for clinical interventions. We integrate several literatures: Using the database PsycInfo, we retrieved empirical studies with the keywords prospection, prediction, expectation, pessimism, mental simulation, future-thinking, future-directed thinking, foresight, and/or mental time travel, in conjunction with depression, depressed, or depressive. Three kinds of faulty prospection, taken together, could drive depression: Poor generation of possible futures, poor evaluation of possible futures, and negative beliefs about the future. Depressed mood and poor functioning, in turn, may maintain faulty prospection and feed a vicious cycle. Future-oriented treatment strategies drawn from cognitive-behavioural therapy help to fix poor prospection, and they deserve to be developed further. Prospection-based techniques may lead to transdiagnostic treatment strategies for depression and other disorders. © 2015 The British Psychological Society.

  3. How Adolescents Construct Their Future: The Effect of Loneliness on Future Orientation

    ERIC Educational Resources Information Center

    Seginer, Rachel; Lilach, Efrat

    2004-01-01

    This study examined the effect of loneliness, gender, and two dimensions of prospective life domains on adolescent future orientation. Future orientation was studied in four prospective domains: social relations, marriage and family, higher education and work and career. These domains are described in terms of two dimensions: theme (relational vs.…

  4. Prospective Teachers' Future Time Perspective and Professional Plans about Teaching: The Mediating Role of Academic Optimism

    ERIC Educational Resources Information Center

    Eren, Altay

    2012-01-01

    This study aimed to examine the mediating role of prospective teachers' academic optimism in the relationship between their future time perspective and professional plans about teaching. A total of 396 prospective teachers voluntarily participated in the study. Correlation, regression, and structural equation modeling analyses were conducted in…

  5. From Present Surveying to Future Prospecting of the Asteroid Belt

    NASA Astrophysics Data System (ADS)

    Clark, P. E.; Curtis, S. A.; Rilee, M.; Cheung, C.

    2004-03-01

    Requirements are analyzed for application of future mission architecture, the Autonomous Nano-Technology Swarm (ANTS), to proposed in situ prospecting, of the asteroid belt, the Prospecting Asteroid Mission (PAM) as part of a NASA 2003 Revolutionary Aerospace Concept (RASC) study.

  6. Factors Influencing Teaching Choice, Professional Plans about Teaching, and Future Time Perspective: A Mediational Analysis

    ERIC Educational Resources Information Center

    Eren, Altay; Tezel, Kadir Vefa

    2010-01-01

    This study aimed to examine the mediating role of prospective English teachers' future time perspectives in relation to their motivations for teaching, beliefs about the profession, career choice satisfaction, and professional plans. A total of 423 prospective English teachers voluntarily participated in the study. The mediating role of the future…

  7. SETI in the future - Toward other possible searches

    NASA Technical Reports Server (NTRS)

    Rummel, John D.

    1992-01-01

    The future prospects of SETI as a scientific endeavor, both in its own right and with respect to the side benefits to science and society, are discussed. Specifically, the consequences of a successful detection and the prospects for follow-on studies in exobiology are addressed.

  8. A taxonomy of prospection: introducing an organizational framework for future-oriented cognition.

    PubMed

    Szpunar, Karl K; Spreng, R Nathan; Schacter, Daniel L

    2014-12-30

    Prospection--the ability to represent what might happen in the future--is a broad concept that has been used to characterize a wide variety of future-oriented cognitions, including affective forecasting, prospective memory, temporal discounting, episodic simulation, and autobiographical planning. In this article, we propose a taxonomy of prospection to initiate the important and necessary process of teasing apart the various forms of future thinking that constitute the landscape of prospective cognition. The organizational framework that we propose delineates episodic and semantic forms of four modes of future thinking: simulation, prediction, intention, and planning. We show how this framework can be used to draw attention to the ways in which various modes of future thinking interact with one another, generate new questions about prospective cognition, and illuminate our understanding of disorders of future thinking. We conclude by considering basic cognitive processes that give rise to prospective cognitions, cognitive operations and emotional/motivational states relevant to future-oriented cognition, and the possible role of procedural or motor systems in future-oriented behavior.

  9. U.S. Natural Gas Markets: Recent Trends and Prospects for the Future

    EIA Publications

    2001-01-01

    The purpose of this study is to examine recent trends and prospects for the future of the U.S. natural gas market. Natural gas prices rose dramatically in 2000 and remained high through the first part of 2001, raising concerns about the future of natural gas prices and potential for natural gas to fuel the growth of the U.S. economy.

  10. How adolescents construct their future: the effect of loneliness on future orientation.

    PubMed

    Seginer, Rachel; Lilach, Efrat

    2004-12-01

    This study examined the effect of loneliness, gender, and two dimensions of prospective life domains on adolescent future orientation. Future orientation was studied in four prospective domains: social relations, marriage and family, higher education and work and career. These domains are described in terms of two dimensions: theme (relational vs. instrumental) and distance (near vs. distant future). Data collected from Israeli Jewish adolescents (11th graders) were analysed by repeated measures ANOVAs and ANCOVAs (covariate: depressive experiences) for seven future orientation variables: value, expectance, control (motivational variables), hopes, fears (cognitive representation variables), exploration, commitment (behavioural variables). As predicted, lonely adolescents scored lower than socially embedded adolescents on future orientation variables applied to the relational and near future domains and lonely boys scored lower than lonely girls. However, effects were found only on the three future orientation motivational variables and not on the cognitive representation and behavioural variables. Contrary to prediction controlling for the effect of depressive experiences did not reduce the effect of loneliness on the future orientation variables, but reduced the tendency of adolescents to score higher on all future orientation variables in the instrumental than in the relational prospective domains. The contribution of these findings to the understanding of adolescent loneliness and future orientation was discussed and directions for future research were suggested.

  11. The organization of prospective thinking: evidence of event clusters in freely generated future thoughts.

    PubMed

    Demblon, Julie; D'Argembeau, Arnaud

    2014-02-01

    Recent research suggests that many imagined future events are not represented in isolation, but instead are embedded in broader event sequences-referred to as event clusters. It remains unclear, however, whether the production of event clusters reflects the underlying organizational structure of prospective thinking or whether it is an artifact of the event-cuing task in which participants are explicitly required to provide chains of associated future events. To address this issue, the present study examined whether the occurrence of event clusters in prospective thought is apparent when people are left to think freely about events that might happen in their personal future. The results showed that the succession of events participants spontaneously produced when envisioning their future frequently included event clusters. This finding provides more compelling evidence that prospective thinking involves higher-order autobiographical knowledge structures that organize imagined events in coherent themes and sequences. Copyright © 2014 Elsevier Inc. All rights reserved.

  12. Phenomenology of future-oriented mind-wandering episodes

    PubMed Central

    Stawarczyk, David; Cassol, Helena; D'Argembeau, Arnaud

    2013-01-01

    Recent research suggests that prospective and non-prospective forms of mind-wandering possess distinct properties, yet little is known about what exactly differentiates between future-oriented and non-future-oriented mind-wandering episodes. In the present study, we used multilevel exploratory factor analyses (MEFA) to examine the factorial structure of various phenomenological dimensions of mind-wandering, and we then investigated whether future-oriented mind-wandering episodes differ from other classes of mind-wandering along the identified factors. We found that the phenomenological dimensions of mind-wandering are structured in four factors: representational format (inner speech vs. visual imagery), personal relevance, realism/concreteness, and structuration. Prospective mind-wandering differed from non-prospective mind-wandering along each of these factors. Specifically, future-oriented mind-wandering episodes involved inner speech to a greater extent, were more personally relevant, more realistic/concrete, and more often part of structured sequences of thoughts. These results show that future-oriented mind-wandering possesses a unique phenomenological signature and provide new insights into how this particular form of mind-wandering may adaptively contribute to autobiographical planning. PMID:23882236

  13. Stakeholder Views on the Roles, Challenges, and Future Prospects of Korean and Chinese Heritage Language-Community Language Schools in Phoenix: A Comparative Study

    ERIC Educational Resources Information Center

    You, Byeong-keun; Liu, Na

    2011-01-01

    This study examines stakeholders' perspectives on Korean and Chinese heritage language and community language (HL-CL) schools and education in the Phoenix Metropolitan Area, Arizona. It investigates and compares the roles, major challenges, and future prospects of Korean and Chinese HL-CL schools as viewed by principals, teachers, and parents. To…

  14. Future thinking improves prospective memory performance and plan enactment in older adults.

    PubMed

    Altgassen, Mareike; Rendell, Peter G; Bernhard, Anka; Henry, Julie D; Bailey, Phoebe E; Phillips, Louise H; Kliegel, Matthias

    2015-01-01

    Efficient intention formation might improve prospective memory by reducing the need for resource-demanding strategic processes during the delayed performance interval. The present study set out to test this assumption and provides the first empirical assessment of whether imagining a future action improves prospective memory performance equivalently at different stages of the adult lifespan. Thus, younger (n = 40) and older (n = 40) adults were asked to complete the Dresden Breakfast Task, which required them to prepare breakfast in accordance with a set of rules and time restrictions. All participants began by generating a plan for later enactment; however, after making this plan, half of the participants were required to imagine themselves completing the task in the future (future thinking condition), while the other half received standard instructions (control condition). As expected, overall younger adults outperformed older adults. Moreover, both older and younger adults benefited equally from future thinking instructions, as reflected in a higher proportion of prospective memory responses and more accurate plan execution. Thus, for both younger and older adults, imagining the specific visual-spatial context in which an intention will later be executed may serve as an easy-to-implement strategy that enhances prospective memory function in everyday life.

  15. Conceptual Paradigms and Empirical Investigations for Evaluating INTELSAT's Past Performance and Future Prospects.

    ERIC Educational Resources Information Center

    Snow, Marcellus S.

    This paper summarizes the results of a recent study of the past performance and future prospects of the International Telecommunications Satellite (INTELSAT) Organization. First, an overview of INTELSAT's history is provided and major policy issues are detailed. Five alternative paradigms are then presented through which to evaluate INTELSAT's…

  16. Stylistics in Teacher Training: Research Programs and Future Prospects

    ERIC Educational Resources Information Center

    Ventura, Ana Clara

    2016-01-01

    The aim of this research is to analyse and systematize the conceptual and empirical bases of the available literature on research approaches, objects of study, and future prospects in the field of stylistics, in order to encourage best practice in teacher training. Three research approaches are presented: the empiricist-behaviorist approach, the…

  17. Future thinking instructions improve prospective memory performance in adolescents.

    PubMed

    Altgassen, Mareike; Kretschmer, Anett; Schnitzspahn, Katharina Marlene

    2017-07-01

    Studies on prospective memory (PM) development in adolescents point to age-related increases through to adulthood. The goal of the present study was to examine whether instructing adolescents to engage in an episodic prospection of themselves executing future actions (i.e., future thinking) when forming an intention would improve their PM performance and reduce age-related differences. Further, we set out to explore whether future thinking instructions result in stronger memory traces and/or stronger cue-context associations by evaluating retrospective memory for the PM cues after task completion and monitoring costs during PM task processing. Adolescents and young adults were allocated to either the future thinking, repeated-encoding or standard condition. As expected, adolescents had fewer correct PM responses than young adults. Across age groups, PM performance in the standard condition was lower than in the other encoding conditions. Importantly, the results indicate a significant interaction of age by encoding condition. While adolescents benefited most from future thinking instructions, young adults performed best in the repeated-encoding condition. The results also indicate that the beneficial effects of future thinking may result from deeper intention-encoding through the simulation of future task performance.

  18. Proceedings of the conference on alternative energy sources for Texas

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rothman, I.N.

    1981-01-01

    Four primary areas of study for alternative energy sources for Texas are considered. These are: energy demand supply and economics; prospects for energy resources (oil, lignite, coal, nuclear, goethermal and solar) and conservation; financial and technical constraints; and future planning. The following papers are presented: US energy outlook to 1990; energy supply and demand projections; comparative economics of solar energy in the generation of big power; gas present and future prospects; prospects for enhanced recovery of oil in Texas; the outlook for coal in USA; implementation of nuclear power in Texas; future outlook - geopressured-geothermal energy for Texas; future prospectsmore » for conservation and solar energy; financing and money supply constraints; technical constraints to energy supply increase; planning for the future - the crisis that drones on. Two papers have been abstracted separately.« less

  19. Views of HR Specialists on Formal Mentoring: Current Situation and Prospects for the Future

    ERIC Educational Resources Information Center

    Laiho, Maarit; Brandt, Tiina

    2012-01-01

    Purpose: The article aims to report the findings of quantitative and qualitative analysis of the benefits, drawbacks and future prospects of formal mentoring in medium-sized and large organisations. Design/methodology/approach: The empirical data for the study were collected via an online survey, and consist of responses from 152 human resource…

  20. Prospect of future housing and risk of psychological distress at 1 year after an earthquake disaster.

    PubMed

    Nakaya, Naoki; Nakamura, Tomohiro; Tsuchiya, Naho; Narita, Akira; Tsuji, Ichiro; Hozawa, Atsushi; Tomita, Hiroaki

    2016-04-01

    Since the Great East Japan Earthquake in 2011, many of the affected have been forced to live in temporary housing or at a relative's house. Special attention needs to be paid to the negative health impacts resulting from such changes in living conditions. This study examined the association between future housing prospects and the risk of psychological distress 1 year after the earthquake. In 2012, a questionnaire was completed by a cross-sectional study of people aged 20 years or older living in Shichigahama Town, Miyagi, northeastern Japan, an area that had been severely inundated by the tsunami. Future housing prospects post-earthquake were classified into four categories: already settled in permanent housing, moving to new housing, under consideration, or unable to make any plans. Psychological distress was evaluated using the Kessler 6 scale, defined as ≥5 points out of 24. We performed multiple logistic regression analyses adjusted for potential confounding factors. Of the 3614 individuals studied, subjects whose future housing was under consideration (odds ratio [OR] = 2.1, 95% confidence interval [CI] = 1.6-2.7, P < 0.01) and those who were unable to make any future housing plans (OR = 1.9, 95%CI = 1.4-2.5, P < 0.01) exhibited a significantly higher risk of psychological distress compared with subjects who had already settled in permanent housing. In this study, subjects whose future housing prospects were under consideration and those who were unable to make any future housing plans were at a higher risk of psychological distress 1 year after the earthquake disaster. © 2015 The Authors. Psychiatry and Clinical Neurosciences © 2015 Japanese Society of Psychiatry and Neurology.

  1. Does Involuntary Mental Time Travel Make Sense in Prospective Teachers' Feelings and Behaviors during Lessons?

    ERIC Educational Resources Information Center

    Eren, Altay; Yesilbursa, Amanda

    2013-01-01

    This study examined the effects of involuntary mental time travel into the past and into the future on prospective teachers' feelings and behaviors during the period of a class hour. A total of 110 prospective teachers participated voluntarily in the study. The results of the present study showed that (a) the involuntary mental time travel into…

  2. A taxonomy of prospection: Introducing an organizational framework for future-oriented cognition

    PubMed Central

    Szpunar, Karl K.; Spreng, R. Nathan; Schacter, Daniel L.

    2014-01-01

    Prospection—the ability to represent what might happen in the future—is a broad concept that has been used to characterize a wide variety of future-oriented cognitions, including affective forecasting, prospective memory, temporal discounting, episodic simulation, and autobiographical planning. In this article, we propose a taxonomy of prospection to initiate the important and necessary process of teasing apart the various forms of future thinking that constitute the landscape of prospective cognition. The organizational framework that we propose delineates episodic and semantic forms of four modes of future thinking: simulation, prediction, intention, and planning. We show how this framework can be used to draw attention to the ways in which various modes of future thinking interact with one another, generate new questions about prospective cognition, and illuminate our understanding of disorders of future thinking. We conclude by considering basic cognitive processes that give rise to prospective cognitions, cognitive operations and emotional/motivational states relevant to future-oriented cognition, and the possible role of procedural or motor systems in future-oriented behavior. PMID:25416592

  3. Health priorities and public preferences: the relative importance of past health experience and future health prospects.

    PubMed

    Dolan, Paul; Tsuchiya, Aki

    2005-07-01

    We explore people's choices where the preference for those with worse future health prospects and the preference for the young over the old conflict. The empirical study used scenarios with four attributes: past years, past health, future years without treatment, and future health without treatment. One hundred respondents ranked various patient groups described in these terms. The results suggest a strong effect of past years: younger groups (40-year-olds) were always chosen over older ones (60-year-olds). Past health was significant in one question but not the other and future health and years without treatment were both non-significant.

  4. Escaping the impulse to immediate gratification: the prospect concept promotes a future-oriented mindset, prompting an inclination towards delayed gratification.

    PubMed

    Cheng, Ying-Yao; Shein, Paichi Pat; Chiou, Wen-Bin

    2012-02-01

    People's willingness to postpone receiving an immediate reward in order to gain additional benefits in the future, that is, a tendency to shallow delay discounting, is closely related to one's health, wealth, and happiness. We conducted two experiments investigating how the prospect concept can induce a future-oriented mindset and induce people to behave accordingly. We found that engaging in prospective imagery led the participants to focus on delayed utility over immediate utility in financial decisions (Experiment 1). Participants who received the prospect prime via a scrambled-sentence task decreased their desire to pursue hedonic activities for instant gratification (Experiment 2). Moreover, a state of future orientation mediated the effect of the prospect prime on measures of delayed gratification (Experiments 1 and 2). Thus, reminders of prospect may activate a mindset for future orientation by which delayed gratification is strengthened. ©2011 The British Psychological Society.

  5. Prospective content in the friendship conversations of young adults.

    PubMed

    Young, Richard A; Marshall, Sheila K; Murray, John

    2017-01-01

    Prospection is cognitive processes that involve constructing, encoding, and remembering the future. Less is known about the how these processes are evident in the prospective content of conversations. This study sought to identify and describe evidence of the prospective content in the conversations of friends as they transition to adulthood. The present secondary content analysis of the videotaped conversations of 15 young adult friendship dyads (n = 30, 16 females, 14 males, mean age = 21.3 years) in Canada examined these conversations based the following characteristics of prospection: simulation, reasoning about counterfactuals, constructing multiple possible futures, and episodic memory of the past. Four categories of prospective content were evident in these conversations, these processes were used sparingly in all but one conversation, and relatively few of them were collaborative in that dyad partners did not appear to serve to augment, clarify, or disconfirm prospective content. Copyright © 2016 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

  6. Improving prospective memory performance with future event simulation in traumatic brain injury patients.

    PubMed

    Mioni, Giovanna; Bertucci, Erica; Rosato, Antonella; Terrett, Gill; Rendell, Peter G; Zamuner, Massimo; Stablum, Franca

    2017-06-01

    Previous studies have shown that traumatic brain injury (TBI) patients have difficulties with prospective memory (PM). Considering that PM is closely linked to independent living it is of primary interest to develop strategies that can improve PM performance in TBI patients. This study employed Virtual Week task as a measure of PM, and we included future event simulation to boost PM performance. Study 1 evaluated the efficacy of the strategy and investigated possible practice effects. Twenty-four healthy participants performed Virtual Week in a no strategy condition, and 24 healthy participants performed it in a mixed condition (no strategy - future event simulation). In Study 2, 18 TBI patients completed the mixed condition of Virtual Week and were compared with the 24 healthy controls who undertook the mixed condition of Virtual Week in Study 1. All participants also completed a neuropsychological evaluation to characterize the groups on level of cognitive functioning. Study 1 showed that participants in the future event simulation condition outperformed participants in the no strategy condition, and these results were not attributable to practice effects. Results of Study 2 showed that TBI patients performed PM tasks less accurately than controls, but that future event simulation can substantially reduce TBI-related deficits in PM performance. The future event simulation strategy also improved the controls' PM performance. These studies showed the value of future event simulation strategy in improving PM performance in healthy participants as well as in TBI patients. TBI patients performed PM tasks less accurately than controls, confirming prospective memory impairment in these patients. Participants in the future event simulation condition out-performed participants in the no strategy condition. Future event simulation can substantially reduce TBI-related deficits in PM performance. Future event simulation strategy also improved the controls' PM performance. © 2017 The British Psychological Society.

  7. From memory to prospection: what are the overlapping and the distinct components between remembering and imagining?

    PubMed Central

    Zheng, Huimin; Luo, Jiayi; Yu, Rongjun

    2014-01-01

    Reflecting on past events and reflecting on future events are two fundamentally different processes, each traveling in the opposite direction of the other through conceptual time. But what we are able to imagine seems to be constrained by what we have previously experienced, suggesting a close link between memory and prospection. Recent theories suggest that recalling the past lies at the core of imagining and planning for the future. The existence of this link is supported by evidence gathered from neuroimaging, lesion, and developmental studies. Yet it is not clear exactly how the novel episodes people construct in their sense of the future develop out of their historical memories. There must be intermediary processes that utilize memory as a basis on which to generate future oriented thinking. Here, we review studies on goal-directed processing, associative learning, cognitive control, and creativity and link them with research on prospection. We suggest that memory cooperates with additional functions like goal-directed learning to construct and simulate novel events, especially self-referential events. The coupling between memory-related hippocampus and other brain regions may underlie such memory-based prospection. Abnormalities in this constructive process may contribute to mental disorders such as schizophrenia. PMID:25147532

  8. Student Teachers' Conceptions of Teaching Biology

    ERIC Educational Resources Information Center

    Subramaniam, Karthigeyan

    2014-01-01

    The purpose of this qualitative study was to investigate prospective biology teachers' conceptions of teaching biology and identify how these conceptions revealed their strategies for helping their future students' learning of biology. The study utilized drawings, narratives and interviews to investigate the nature of the prospective biology…

  9. Children's planning performance in the Zoo Map task (BADS-C): Is it driven by general cognitive ability, executive functioning, or prospection?

    PubMed

    Ballhausen, Nicola; Mahy, Caitlin E V; Hering, Alexandra; Voigt, Babett; Schnitzspahn, Katharina M; Lagner, Prune; Ihle, Andreas; Kliegel, Matthias

    2017-01-01

    A minimal amount of research has examined the cognitive predictors of children's performance in naturalistic, errand-type planning tasks such as the Zoo Map task of the Behavioral Assessment of the Dysexecutive Syndrome for Children (BADS-C). Thus, the current study examined prospection (i.e., the ability to remember to carry out a future intention), executive functioning, and intelligence markers as predictors of performance in this widely used naturalistic planning task in 56 children aged 7- to 12-years-old. Measures of planning, prospection, inhibition, crystallized intelligence, and fluid intelligence were collected in an individual differences study. Regression analyses showed that prospection (rather than traditional measures of intelligence or inhibition) predicted planning, suggesting that naturalistic planning tasks such as the Zoo Map task may rely on future-oriented cognitive processes rather than executive problem solving or general knowledge.

  10. Back to the future: autobiographical planning and the functionality of mind-wandering.

    PubMed

    Baird, Benjamin; Smallwood, Jonathan; Schooler, Jonathan W

    2011-12-01

    Given that as much as half of human thought arises in a stimulus independent fashion, it would seem unlikely that such thoughts would play no functional role in our lives. However, evidence linking the mind-wandering state to performance decrement has led to the notion that mind-wandering primarily represents a form of cognitive failure. Based on previous work showing a prospective bias to mind-wandering, the current study explores the hypothesis that one potential function of spontaneous thought is to plan and anticipate personally relevant future goals, a process referred to as autobiographical planning. The results confirm that the content of mind-wandering is predominantly future-focused, demonstrate that individuals with high working memory capacity are more likely to engage in prospective mind-wandering, and show that prospective mind-wandering frequently involves autobiographical planning. Together this evidence suggests that mind-wandering can enable prospective cognitive operations that are likely to be useful to the individual as they navigate through their daily lives. Copyright © 2011 Elsevier Inc. All rights reserved.

  11. Prospective Memory in a Language-Trained Chimpanzee ("Pan Troglodytes")

    ERIC Educational Resources Information Center

    Beran, Michael J.; Perdue, Bonnie M.; Bramlett, Jessica L.; Menzel, Charles R.; Evans, Theodore A.

    2012-01-01

    Prospective memory involves the encoding, retention, and implementation of an intended future action. Although humans show many forms of prospective memory, less is known about the future oriented processes of nonhuman animals, or their ability to use prospective memory. In this experiment, a chimpanzee named Panzee, who had learned to associate…

  12. Effects of emotion on prospection during decision-making.

    PubMed

    Worthy, Darrell A; Byrne, Kaileigh A; Fields, Sherecce

    2014-01-01

    In two experiments we examined the role of emotion, specifically worry, anxiety, and mood, on prospection during decision-making. Worry is a particularly relevant emotion to study in the context of prospection because high levels of worry may make individuals more aversive toward the uncertainty associated with the prospect of obtaining future improvements in rewards or states. Thus, high levels of worry might lead to reduced prospection during decision-making and enhance preference for immediate over delayed rewards. In Experiment 1 participants performed a two-choice dynamic decision-making task where they were required to choose between one option (the decreasing option) which provided larger immediate rewards but declines in future states, and another option (the increasing option) which provided smaller immediate rewards but improvements in future states, making it the optimal choice. High levels of worry were associated with poorer performance in the task. Additionally, fits of a sophisticated reinforcement-learning model that incorporated both reward-based and state-based information suggested that individuals reporting high levels of worry gave greater weight to the immediate rewards they would receive on each trial than to the degree to which each action would lead to improvements in their future state. In Experiment 2 we found that high levels of worry were associated with greater delay discounting using a standard delay discounting task. Combined, the results suggest that high levels of worry are associated with reduced prospection during decision-making. We attribute these results to high worriers' aversion toward the greater uncertainty associated with attempting to improve future rewards than to maximize immediate reward. These results have implications for researchers interested in the effects of emotion on cognition, and suggest that emotion strongly affects the focus on temporal outcomes during decision-making.

  13. Self-reflection and the temporal focus of the wandering mind.

    PubMed

    Smallwood, Jonathan; Schooler, Jonathan W; Turk, David J; Cunningham, Sheila J; Burns, Phebe; Macrae, C Neil

    2011-12-01

    Current accounts suggest that self-referential thought serves a pivotal function in the human ability to simulate the future during mind-wandering. Using experience sampling, this hypothesis was tested in two studies that explored the extent to which self-reflection impacts both retrospection and prospection during mind-wandering. Study 1 demonstrated that a brief period of self-reflection yielded a prospective bias during mind-wandering such that participants' engaged more frequently in spontaneous future than past thought. In Study 2, individual differences in the strength of self-referential thought - as indexed by the memorial advantage for self rather than other-encoded items - was shown to vary with future thinking during mind-wandering. Together these results confirm that self-reflection is a core component of future thinking during mind-wandering and provide novel evidence that a key function of the autobiographical memory system may be to mentally simulate events in the future. Copyright © 2011 Elsevier Inc. All rights reserved.

  14. SOFRA and RPA: two views of the future of southern timber supply.

    Treesearch

    Darius Adams; John Mills; Ralph Alig; Richard Haynes

    2005-01-01

    Two recent studies provide alternative views of the current state and future prospects of southern forests and timber supply: the Southern Forest Resource Assessment (SOFRA) and the Fifth Resources Planning Act Timber Assessment (RPA). Using apparently comparable data but different models and methods, the studies portray futures that in some aspects are quite similar...

  15. When remembering the past suppresses memory for future actions.

    PubMed

    Utsumi, Kenta; Saito, Satoru

    2016-01-01

    Remembering planned actions at the correct time in the future is an integral component of prospective cognition. Recent studies on future remembering have led to suggestions that prospective cognition might be based on past experience. To test this hypothesis, we focused on retrieval-induced forgetting (RIF), which usually indicates that remembering past events suppresses memory for related but different past events. The current study assessed RIF in two kinds of event-based prospective memory (PM) tasks using either focal or non-focal cues for ongoing tasks. Participants studied six members from each of eight taxonomic categories and then practiced recalling three of the six members from four of the eight categories using category-stem cues. This retrieval practice suppressed the detection of non-practiced members of the practiced categories during the PM task with non-focal cues (Experiment 1) but not with focal cues (Experiment 2). The results suggest that recall of certain items inhibits the function of the others as PM cues, but only if the PM task does not largely share its processing with the ongoing task.

  16. Prospective memory: A comparative perspective

    PubMed Central

    Crystal, Jonathon D.; Wilson, A. George

    2014-01-01

    Prospective memory consists of forming a representation of a future action, temporarily storing that representation in memory, and retrieving it at a future time point. Here we review the recent development of animal models of prospective memory. We review experiments using rats that focus on the development of time-based and event-based prospective memory. Next, we review a number of prospective-memory approaches that have been used with a variety of non-human primates. Finally, we review selected approaches from the human literature on prospective memory to identify targets for development of animal models of prospective memory. PMID:25101562

  17. (Some) Computer Futures: Mainframes.

    ERIC Educational Resources Information Center

    Joseph, Earl C.

    Possible futures for the world of mainframe computers can be forecast through studies identifying forces of change and their impact on current trends. Some new prospects for the future have been generated by advances in information technology; for example, recent United States successes in applied artificial intelligence (AI) have created new…

  18. Losing sight of the future: Impaired semantic prospection following medial temporal lobe lesions

    PubMed Central

    Race, Elizabeth; Keane, Margaret M.; Verfaellie, Mieke

    2012-01-01

    The ability to imagine the future (prospection) relies on many of the same brain regions that support memory for the past. To date, scientific research has primarily focused on the neural substrates of episodic forms of prospection (mental simulation of spatiotemporally specific future events) whereas little is known about the neural substrates of semantic prospection (mental simulation of future nonpersonal facts). Of particular interest is the role of the medial temporal lobes, and specifically the hippocampus. While the hippocampus has been proposed to play a key role in episodic prospection, recent evidence suggests that it may not play a similar role in semantic prospection. To examine this possibility, amnesic patients with medial temporal lobe (MTL) lesions were asked to imagine future issues occurring in the public domain. The results showed that patients could list general semantic facts about the future, but when probed to elaborate, patients produced impoverished descriptions that lacked semantic detail. This impairment occurred despite intact performance on standard neuropsychological tests of semantic processing, and did not simply reflect deficits in narrative construction. The performance of a patient with damage limited to the hippocampus was similar to that of the remaining MTL patients and amnesic patients’ impaired elaboration of the semantic future correlated with their impaired elaboration of the semantic past. Together, these results provide novel evidence from MTL amnesia that memory and prospection are linked in the semantic domain and reveal that the medial temporal lobes play a critical role in the construction of detailed, multi-element semantic simulations. PMID:23197413

  19. Effects of cue frequency and repetition on prospective memory: an ERP investigation.

    PubMed

    Wilson, Jennifer; Cutmore, Tim R H; Wang, Ya; Chan, Raymond C K; Shum, David H K

    2013-11-01

    Prospective memory involves the formation and completion of delayed intentions and is essential for independent living. In this study (n = 33), event-related potentials (ERPs) were used to systematically evaluate the effects of PM cue frequency (10% versus 30%) and PM cue repetition (high versus low) on ERP modulations. PM cues elicited prospective positivity and frontal positivity but not N300, perhaps due to the semantic nature of the task. Results of this study revealed an interesting interaction between PM cue frequency and PM cue repetition for prospective positivity and frontal positivity, highlighting the importance of taking both factors into account when designing future studies. © 2013.

  20. Perceived future career prospects in general practice: quantitative results from questionnaire surveys of UK doctors

    PubMed Central

    Lambert, Trevor W; Smith, Fay; Goldacre, Michael J

    2016-01-01

    Background There are more studies of current job satisfaction among GPs than of their views about their future career prospects, although both are relevant to commitment to careers in general practice. Aim To report on the views of GPs compared with clinicians in other specialties about their future career prospects. Design and setting Questionnaire surveys were sent to UK medical doctors who graduated in selected years between 1974 and 2008. Method Questionnaires were sent to the doctors at different times after graduation, ranging from 3 to 24 years. Results Based on the latest survey of each graduation year of the 20 940 responders, 66.2% of GPs and 74.2% of hospital doctors were positive about their prospects and 9.7% and 8.3%, respectively, were negative. However, with increasing time since graduation and increasing levels of seniority, GPs became less positive about their prospects; by contrast, over time, surgeons became more positive. Three to 5 years after graduation, 86.3% of those training in general practice were positive about their prospects compared with 52.9% of surgical trainees: in surveys conducted 12–24 years after graduation, 60.2% of GPs and 76.6% of surgeons were positive about their prospects. Conclusion GPs held broadly positive views of their career prospects, as did other doctors. However, there was an increase in negativity with increasing time since graduation that was not seen in hospital doctors. Research into the causes of this negativity and policy measures to ameliorate it would contribute to the continued commitment of GPs and may help to reduce attrition. PMID:27578813

  1. Predictors of self-rated health: a 12-month prospective study of IT and media workers.

    PubMed

    Hasson, Dan; Arnetz, Bengt B; Theorell, Töres; Anderberg, Ulla Maria

    2006-07-31

    The aim of the present study was to determine health-related risk and salutogenic factors and to use these to construct prediction models for future self-rated health (SRH), i.e. find possible characteristics predicting individuals improving or worsening in SRH over time (0-12 months). A prospective study was conducted with measurements (physiological markers and self-ratings) at 0, 6 and 12 months, involving 303 employees (187 men and 116 women, age 23-64) from four information technology and two media companies. There were a multitude of statistically significant cross-sectional correlations (Spearman's Rho) between SRH and other self-ratings as well as physiological markers. Predictors of future SRH were baseline ratings of SRH, self-esteem and social support (logistic regression), and SRH, sleep quality and sense of coherence (linear regression). The results of the present study indicate that baseline SRH and other self-ratings are predictive of future SRH. It is cautiously implied that SRH, self-esteem, social support, sleep quality and sense of coherence might be predictors of future SRH and therefore possibly also of various future health outcomes.

  2. Prospective Primary Teachers' Beliefs about Mathematics

    ERIC Educational Resources Information Center

    Maasepp, Brooke; Bobis, Janette

    2015-01-01

    Concerns about the negative mathematical beliefs of prospective primary teachers have arisen from evidence that such beliefs detrimentally impact future teaching practices. The aim of this study was to explore factors contributing to the effectiveness of a mathematics content-focused intervention designed to nurture positive mathematical beliefs.…

  3. The influence of emotional cues on prospective memory: a systematic review with meta-analyses.

    PubMed

    Hostler, Thomas J; Wood, Chantelle; Armitage, Christopher J

    2018-01-10

    Remembering to perform a behaviour in the future, prospective memory, is essential to ensuring that people fulfil their intentions. Prospective memory involves committing to memory a cue to action (encoding), and later recognising and acting upon the cue in the environment (retrieval). Prospective memory performance is believed to be influenced by the emotionality of the cues, however the literature is fragmented and inconsistent. We conducted a systematic search to synthesise research on the influence of emotion on prospective memory. Sixty-seven effect sizes were extracted from 17 articles and hypothesised effects tested using three meta-analyses. Overall, prospective memory was enhanced when positively-valenced rather than neutral cues were presented (d = 0.32). In contrast, negatively-valenced cues did not enhance prospective memory overall (d = 0.07), but this effect was moderated by the timing of the emotional manipulation. Prospective memory performance was improved when negatively-valenced cues were presented during both encoding and retrieval (d = 0.40), but undermined when presented only during encoding (d = -0.25). Moderating effects were also found for cue-focality and whether studies controlled for the arousal level of the cues. The principal finding is that positively-valenced cues improve prospective memory performance and that timing of the manipulation can moderate emotional effects on prospective memory. We offer a new agenda for future empirical work and theorising in this area.

  4. [Prospective memory - concepts, methods of assessment, neuroanatomical bases and its deficits in mental disorders].

    PubMed

    Wiłkość, Monika; Izdebski, Paweł; Zajac-Lamparska, Ludmiła

    2013-01-01

    In the last two decades of the last century there has been a shift in the studies on memory. In psychology of memory the criticism of the laboratory approach resulted in development of the ecological approach. One of the effects of this change was to initiate researches on memory that includes plans for the future, which has resulted in the distinction of the concept of prospective memory. Prospective memory is used in many aspects of everyday life. It deals with remembering intentions and plans, it is connected with remembering about specific task or activity in the future. There are three types of PM: event-based prospective memory, time-based prospective memory and activity-based prospective memory. Current research in this field have already established its own paradigm and tools measuring PM and there is still increasing scientific interest in this issue. Prospective memory assessment may be carried out in various ways. Among them, the most frequently used are: a) questionnaires, b) psychological tests, c) experimental procedures. Within the latter, the additional distinction can be introduced for: the experiments conducted under natural conditions and the laboratory procedures. In Polish literature, there are only a few articles on PM. The aim of this work is to review studies on assessment methods of PM. Its neuroanatomical bases and its functioning in different mental disorders are analyzed. The work is aimed to focus clinicians attention on prospective memory as an area which is important for complex diagnosis of cognitive processes.

  5. A Prospective Test of Cognitive Vulnerability Models of Depression with Adolescent Girls

    ERIC Educational Resources Information Center

    Bohon, Cara; Stice, Eric; Burton, Emily; Fudell, Molly; Nolen-Hoeksema, Susan

    2008-01-01

    This study sought to provide a more rigorous prospective test of two cognitive vulnerability models of depression with longitudinal data from 496 adolescent girls. Results supported the cognitive vulnerability model in that stressors predicted future increases in depressive symptoms and onset of clinically significant major depression for…

  6. Prospective Primary Teachers' Self-Efficacy and Emotions in Science Teaching

    ERIC Educational Resources Information Center

    Brigido, Maria; Borrachero, Ana Belen; Bermejo, Maria Luisa; Mellado, Vicente

    2013-01-01

    The self-efficacy of prospective primary teachers was studied, considering in particular the relationship of that construct with the emotions they expect to experience as future science teachers, differentiating between when they will be teaching the content of the "nature sciences" (biology and geology) and that of the "hard…

  7. Psychological and Behavioral Risk Factors for Obesity Onset in Adolescent Girls: A Prospective Study

    ERIC Educational Resources Information Center

    Stice, Eric; Presnell, Katherine; Shaw, Heather; Rohde, Paul

    2005-01-01

    Because little is known about risk factors for obesity, the authors tested whether certain psychological and behavioral variables predicted future onset of obesity. The authors used data from a prospective study of 496 adolescent girls who completed a baseline assessment at age 11-15 years and 4 annual follow-ups. Self-reported dietary restraint,…

  8. Freshman Year Alcohol and Marijuana Use Prospectively Predict Time to College Graduation and Subsequent Adult Roles and Independence

    ERIC Educational Resources Information Center

    Wilhite, Emily R.; Ashenhurst, James R.; Marino, Elise N.; Fromme, Kim

    2017-01-01

    Objective: This study examined how freshman year substance use prospectively predicted time to college graduation, and whether delayed graduation predicted postponed adoption of adult roles and future substance use. Participants: Participants were part of a longitudinal study that began in 2004. The first analyses focused on freshman year (N =…

  9. Future prospects of nuclear reactions induced by gamma-ray beams at ELI-NP

    NASA Astrophysics Data System (ADS)

    Filipescu, D.; Balabanski, D. L.; Camera, F.; Gheorghe, I.; Ghita, D.; Glodariu, T.; Kaur, J.; Ur, C. A.; Utsunomiya, H.; Varlamov, V. V.

    2017-01-01

    The future prospects of photonuclear reactions studies at the new Extreme Light Infrastructure—Nuclear Physics (ELI-NP) facility are discussed in view of the pursuit of investigating the electromagnetic response of nuclei using γ-ray beams of unprecedented energy resolution and intensity characteristics. We present here the features of the γ-ray beam source, the emerging ELI-NP experimental program involving photonuclear reactions cross section measurements and spectroscopy and angular measurements of γ-rays and neutrons along with the detection arrays currently under implementation.

  10. Infants Prospectively Control Reaching Based on the Difficulty of Future Actions: To What Extent Can Infants' Multiple-Step Actions Be Explained by Fitts' Law?

    ERIC Educational Resources Information Center

    Gottwald, Janna M.; De Bortoli Vizioli, Aurora; Lindskog, Marcus; Nyström, Pär; L. Ekberg, Therese; von Hofsten, Claes; Gredebäck, Gustaf

    2017-01-01

    Prospective motor control, a key element of action planning, is the ability to adjust one's actions with respect to task demands and action goals in an anticipatory manner. The current study investigates whether 14-month-olds can prospectively control their reaching actions based on the difficulty of the subsequent action. We used a reach-to-place…

  11. Time-Based and Event-Based Prospective Memory in Autism Spectrum Disorder: The Roles of Executive Function and Theory of Mind, and Time-Estimation

    ERIC Educational Resources Information Center

    Williams, David; Boucher, Jill; Lind, Sophie; Jarrold, Christopher

    2013-01-01

    Prospective memory (remembering to carry out an action in the future) has been studied relatively little in ASD. We explored time-based (carry out an action at a pre-specified time) and event-based (carry out an action upon the occurrence of a pre-specified event) prospective memory, as well as possible cognitive correlates, among 21…

  12. Predicting Ecstasy Use among Young People at Risk: A Prospective Study of Initially Ecstasy-Naive Subjects

    ERIC Educational Resources Information Center

    Vervaeke, Hylke K.E.; Benschop, Annemieke; Van Den Brink, Wim; Korf, Dirk J.

    2008-01-01

    Our aim is to identify predictors of first-time ecstasy use in a prospective study among young people at risk. As part of the multidisciplinary Netherlands XTC Toxicity Study (NeXT), we monitored 188 subjects aged up to 18 years who were ecstasy-naive at baseline but seemed likely to start taking ecstasy in the near future. After an 11- to…

  13. Associations between vertebral fractures, increased thoracic kyphosis, a flexed posture and falls in older adults: a prospective cohort study.

    PubMed

    van der Jagt-Willems, Hanna C; de Groot, Maartje H; van Campen, Jos P C M; Lamoth, Claudine J C; Lems, Willem F

    2015-03-28

    Vertebral fractures, an increased thoracic kyphosis and a flexed posture are associated with falls. However, this was not confirmed in prospective studies. We performed a prospective cohort study to investigate the association between vertebral fractures, increased thoracic kyphosis and/or flexed posture with future fall incidents in older adults within the next year. Patients were recruited at a geriatric outpatient clinic. Vertebral fractures were evaluated on lateral radiographs of the spine with the semi-quantitative method of Genant; the degree of thoracic kyphosis was assessed with the Cobb angle. The occiput-to-wall distance was used to determine a flexed posture. Self-reported falls were prospectively registered by monthly phone contact for the duration of 12 months. Fifty-one older adults were included; mean age was 79 years (SD = 4.8). An increased thoracic kyphosis was independently associated with future falls (OR 2.13; 95% CI 1.10-4.51). Prevalent vertebral fractures had a trend towards significancy (OR 3.67; 95% CI 0.85-15.9). A flexed posture was not significantly associated with future falls. Older adults with an increased thoracic kyphosis are more likely to fall within the next year. We suggest clinical attention for underlying causes. Because patients with increased thoracic curvature of the spine might have underlying osteoporotic vertebral fractures, clinicians should be aware of the risk of a new fracture.

  14. A process-model based approach to prospective memory impairment in Parkinson's disease.

    PubMed

    Kliegel, Matthias; Altgassen, Mareike; Hering, Alexandra; Rose, Nathan S

    2011-07-01

    The present review discusses the current state of research on the clinical neuropsychology of prospective memory in Parkinson's disease. To do so the paper is divided in two sections. In the first section, we briefly outline key features of the (partly implicit) rationale underlying the available literature on the clinical neuropsychology of prospective memory. Here, we present a conceptual model that guides our approach to the clinical neuropsychology of prospective memory in general and to the effects of Parkinson's disease on prospective memory in particular. In the second section, we use this model to guide our review of the available literature and suggest some open issues and future directions motivated by previous findings and the proposed conceptual model. The review suggests that certain phases of the prospective memory process (intention formation und initiation) are particularly impaired by Parkinson's disease. In addition, it is argued that prospective memory may be preserved when tasks involve specific features (e.g., focal cues) that reduce the need for strategic monitoring processes. In terms of suggestions for future directions, it is noted that intervention studies are needed which target the specific phases of the prospective memory process that are impaired in Parkinson's disease, such as planning interventions. Moreover, it is proposed that prospective memory deficits in Parkinson's disease should be explored in the context of a general impairment in the ability to form an intention and plan or coordinate an appropriate series of actions. Copyright © 2011 Elsevier Ltd. All rights reserved.

  15. Impact of episodic thinking on altruism

    PubMed Central

    Yi, Richard; Pickover, Alison; Stuppy-Sullivan, Allison M.; Baker, Sydney; Landes, Reid D.

    2016-01-01

    Episodic future thinking, which refers to the use of prospective imagery to concretely imagine oneself in future scenarios, has been shown to reduce delay discounting (enhance self-control). A parallel approach, in which prospective imagery is used to concretely imagine other’s scenarios, may similarly reduce social discounting (i.e., enhance altruism). In study 1, participants engaged in episodic thinking about the self or others, in a repeated-measures design, while completing a social discounting task. Reductions in social discounting were observed as a function of episodic thinking about others, though an interaction with order was also observed. Using an independent-measures design in study 2, the effect of episodic thinking about others was replicated. Study 3 addressed a limitation of studies 1 and 2, the possibility that simply thinking about others decreased social discounting. Capitalizing on Construal Level Theory, which specifies that social distance and time in the future are both dimensions of a common psychological distance, we hypothesized that episodic future thinking should also decrease social discounting. Participants engaged in episodic future thinking or episodic present thinking, in a repeated-measures design, while completing a social discounting task. The pattern of results was similar to study 1, providing support for the notion that episodic thinking about psychologically distant outcomes (for others or in the future) reduces social discounting. Application of similar episodic thinking approaches may enhance altruism. PMID:27821875

  16. The Influence of Instrumentality Beliefs on Intrinsic Motivation: A Study of High-Achieving Adolescents

    ERIC Educational Resources Information Center

    Kover, David J.; Worrell, Frank C.

    2010-01-01

    For many students, school is a forward-looking endeavor, with implications for future educational opportunity, job prospects, and financial success. How does believing that school is linked to a desired future outcome--known as an instrumentality belief--influence motivation? A number of studies have indicated that rewards, or other concerns that…

  17. The Public Community College in America: Its History, Present Condition, and Future Outlook with Special Reference to Finance.

    ERIC Educational Resources Information Center

    Edwards, Nancy Joan

    The development, current status, and future prospects of community colleges are examined in this study with special emphasis on finance and funding concerns. Introductory material outlines study objectives, methodology, and purposes; defines key terms; and emphasizes the importance of college planning. Chapter 1 presents a history of the community…

  18. Towards an Understanding of Anticipatory Pleasure Deficits in Schizophrenia: Memory, Prospection, and Emotion Experience

    PubMed Central

    Painter, Janelle M.; Kring, Ann M.

    2016-01-01

    Anticipatory pleasure deficits have been observed in people with schizophrenia. Less is known about the extent to which interrelated processes that comprise anticipatory pleasure, including memory, prospection and emotion experience are disrupted. We asked people with (n=32) and without (n=29) schizophrenia or schizoaffective disorder to provide memory and prospection narratives in response to specific cues. Half of the prospections followed a memory task, and half followed a control task. People with schizophrenia generated memories similar in content and experience as controls even as they described them less clearly. However, people with schizophrenia were less likely to explicitly reference the past in their prospections, and their prospections were less detailed and richly experienced than controls, regardless of the task completed before prospection. People with schizophrenia reported similar levels of positive emotion (current and predicted) in positive prospections that followed the memory task, but less positive emotion than controls in positive prospections that followed the control task. Taken together, these results suggest that people with schizophrenia experience difficulties drawing from past experiences and generating detailed prospections. However, asking people with schizophrenia to recall and describe memories prior to prospection may increase the likelihood of drawing from the past in prospections and may help boost current and predicted pleasure. General Scientific Summary People with schizophrenia experience difficulty anticipating future pleasure. This study supports the notion that the “feeling” part of anticipatory pleasure is intact when people with schizophrenia are first asked to generate memories. Thus, recalling and describing positive memories before thinking about the future may help people with schizophrenia to experience greater anticipatory pleasure. PMID:26950753

  19. Prospective memory in schizophrenia: relationship to medication management skills, neurocognition, and symptoms in individuals with schizophrenia.

    PubMed

    Raskin, Sarah A; Maye, Jacqueline; Rogers, Alexandra; Correll, David; Zamroziewicz, Marta; Kurtz, Matthew

    2014-05-01

    Impaired adherence to medication regimens is a serious concern for individuals with schizophrenia linked to relapse and poorer outcomes. One possible reason for poor adherence to medication is poor ability to remember future intentions, labeled prospective memory skills. It has been demonstrated in several studies that individuals with schizophrenia have impairments in prospective memory that are linked to everyday life skills. However, there have been no studies, to our knowledge, examining the relationship of a clinical measure of prospective memory to medication management skills, a key element of successful adherence. In this Study 41 individuals with schizophrenia and 25 healthy adults were administered a standardized test battery that included measures of prospective memory, medication management skills, neurocognition, and symptoms. Individuals with schizophrenia demonstrated impairments in prospective memory (both time and event-based) relative to healthy controls. Performance on the test of prospective memory was correlated with the standardized measure of medication management in individuals with schizophrenia. Moreover, the test of prospective memory predicted skills in medication adherence even after measures of neurocognition were accounted for. This suggests that prospective memory may play a key role in medication management skills and thus should be a target of cognitive remediation programs.

  20. Prospective time-resolved LCA of fully electric supercap vehicles in Germany.

    PubMed

    Zimmermann, Benedikt M; Dura, Hanna; Baumann, Manuel J; Weil, Marcel R

    2015-07-01

    The ongoing transition of the German electricity supply toward a higher share of renewable and sustainable energy sources, called Energiewende in German, has led to dynamic changes in the environmental impact of electricity over the last few years. Prominent scenario studies predict that comparable dynamics will continue in the coming decades, which will further improve the environmental performance of Germany's electricity supply. Life cycle assessment (LCA) is the methodology commonly used to evaluate environmental performance. Previous LCA studies on electric vehicles have shown that the electricity supply for the vehicles' operation is responsible for the major part of their environmental impact. The core question of this study is how the prospective dynamic development of the German electricity mix will affect the impact of electric vehicles operated in Germany and how LCA can be adapted to analyze this impact in a more robust manner. The previously suggested approach of time-resolved LCA, which is located between static and dynamic LCA, is used in this study and compared with several static approaches. Furthermore, the uncertainty issue associated with scenario studies is addressed in general and in relation to time-resolved LCA. Two scenario studies relevant to policy making have been selected, but a moderate number of modifications have been necessary to adapt the data to the requirements of a life cycle inventory. A potential, fully electric vehicle powered by a supercapacitor energy storage system is used as a generic example. The results show that substantial improvements in the environmental repercussions of the electricity supply and, consequentially, of electric vehicles will be achieved between 2020 and 2031 on the basis of the energy mixes predicted in both studies. This study concludes that although scenarios might not be able to predict the future, they should nonetheless be used as data sources in prospective LCA studies, because in many cases historic data appears to be unsuitable for providing realistic information on the future. The time-resolved LCA approach improves the assessment's robustness substantially, especially when nonlinear developments are foreseen in the future scenarios. This allows for a reduction of bias in LCA-based decision making. However, a deeper integration of time-resolved data in the life cycle inventory and the implementation of a more suitable software framework are desirable. The study describes how life cycle assessment's (LCA) robustness can be improved by respecting prospective fluctuations, like the transition of the German electricity mix, in the modeling of the life cycle inventory. It presents a feasible and rather simple process to add time-resolved data to LCA. The study selects 2 different future scenarios from important German studies and processes their data systematically to make them compatible with the requirements of a life cycle inventory. The use of external scenarios as basis for future-oriented LCA is reflected critically. A case study on electric mobility is presented and used to compare historic, prospective static, and prospective time-resolved electricity mix modeling approaches. The case study emphasizes the benefits of time-resolved LCA in direct comparison with the currently used approaches. © 2015 SETAC.

  1. Short-term prospective memory deficits in chronic back pain patients.

    PubMed

    Ling, Jonathan; Campbell, Carol; Heffernan, Thomas M; Greenough, Charles G

    2007-01-01

    Chronic pain, particularly low back pain, is widespread. Although a great deal is known about the impact that this has on quality of life and physical activity, relatively little has been established regarding the more cognitive effects of pain. This study aims to find out whether individuals with chronic pain experience memory deficits in prospective memory (PM), the process of remembering to do things at some future point in time. Examples of PM include remembering to keep an appointment, such as a visit to a clinic, or to perform a particular task, such as paying a bill on time. The PM of 50 participants with chronic pain was compared with 50 pain-free participants. Each participant completed the Prospective Memory Questionnaire, which assesses three aspects of prospective memory (short-term habitual, long-term episodic, and internally cued), and records the use of strategies to aid remembering. In comparison to those not in pain, participants with chronic pain had significantly impaired short-term prospective memory, an effect which was evident even after co-varying use of analgesics and other drugs. These findings provide new insights into prospective memory dysfunction in people with chronic pain. Possible mechanisms for this dysfunction are discussed and suggestions for future research given.

  2. Risk factors for lower extremity injury: a review of the literature

    PubMed Central

    Murphy, D; Connolly, D; Beynnon, B

    2003-01-01

    Prospective studies on risk factors for lower extremity injury are reviewed. Many intrinsic and extrinsic risk factors have been implicated; however, there is little agreement with respect to the findings. Future prospective studies are needed using sufficient sample sizes of males and females, including collection of exposure data, and using established methods for identifying and classifying injury severity to conclusively determine addtional risk factors for lower extremity injury. PMID:12547739

  3. Future Space Transportation Technology: Prospects and Priorities

    NASA Technical Reports Server (NTRS)

    Billie, Matt; Reed, Lisa; Harris, David

    2003-01-01

    The Transportation Working Group (TWG) was chartered by the NASA Exploration Team (NEXT) to conceptualize, define, and advocate within NASA the space transportation architectures and technologies required to enable the human and robotic exploration and development of space envisioned by the NEXT. In 2002, the NEXT tasked the TWG to assess exploration space transportation requirements versus current and prospective Earth-to-Orbit (ETO) and in-space transportation systems, technologies, and research, in order to identify investment gaps and recommend priorities. The result was a study now being incorporated into future planning by the NASA Space Architect and supporting organizations. This paper documents the process used to identify exploration space transportation investment gaps, as well as the group's recommendations for closing these gaps and prioritizing areas of future investment for NASA work on advanced propulsion systems.

  4. Prospective Trends in the Socio-Economic Context of Education in European Market Economy Countries.

    ERIC Educational Resources Information Center

    Weiss, M.; And Others

    The purpose of this study was to project and analyze the prospective long-term trends in the socioeconomic context of the educational systems of European market economies and to outline in global terms the probable implication for education and training in the future. Composed of three chapters, the chapter 1 focuses on projected long-term…

  5. Distance Probes of Dark Energy

    DOE PAGES

    Kim, A. G.; Padmanabhan, N.; Aldering, G.; ...

    2015-03-15

    We present the results from the Distances subgroup of the Cosmic Frontier Community Planning Study (Snowmass 2013). This document summarizes the current state of the field as well as future prospects and challenges. In addition to the established probes using Type Ia supernovae and baryon acoustic oscillations, we also consider prospective methods based on clusters, active galactic nuclei, gravitational wave sirens and strong lensing time delays.

  6. Hopes for the Future: Demographic and Personal Resources Associated with Self-Perceived Employability and Actual Employment among Senior Year Students

    ERIC Educational Resources Information Center

    Kasler, Jonathan; Zysberg, Leehu; Harel, Nofar

    2017-01-01

    Undergraduates approaching completion of their studies may embrace the prospect of entry into the world of work as a challenge or conversely, may view it with trepidation. This study explores three major personal resources that may be associated with how young undergraduates view their future employability: perceived hope, grit and emotional…

  7. Using Drawings to Bridge the Transition from Student to Future Teacher of Mathematics

    ERIC Educational Resources Information Center

    Lee, Ji-Eun; Zeppelin, Mary

    2014-01-01

    This study examines a group of prospective teachers' reflections upon the way they were taught (Set 1) and the way they want to teach (Set 2) through drawings which respectively describe their past learning experiences as students and their future plans as teachers. The purpose of this study is to identify: (a) the emerging themes that appear in…

  8. Does children's screen time predict requests for advertised products? Cross-sectional and prospective analyses.

    PubMed

    Chamberlain, Lisa J; Wang, Yun; Robinson, Thomas N

    2006-04-01

    To examine children's screen media exposure and requests for advertised toys and food/drinks. Prospective cohort study. Twelve elementary schools in northern California. Eight hundred twenty-seven third grade children participated at baseline; 386 students in 6 schools were followed up for 20 months. None. Child self-reported requests for advertised toys and foods/drinks. At baseline, children's screen media time was significantly associated with concurrent requests for advertised toys (Spearman r = 0.15 [TV viewing] and r = 0.20 [total screen time]; both P<.001) and foods/drinks (Spearman r = 0.16 [TV viewing] and r = 0.18 [total screen time]; both P<.001). In prospective analysis, children's screen media time at baseline was significantly associated with their mean number of toy requests 7 to 20 months later (Spearman r = 0.21 [TV viewing] and r = 0.24 [total screen time]; both P<.001) and foods/drinks requests (Spearman r = 0.14 [TV viewing] and r = 0.16 [total screen time]; both P<.01). After adjusting for baseline requests and sociodemographic variables, the relationship between screen media exposure and future requests for advertised foods/drinks remained significant for total TV viewing and total screen media exposure. The relationship with future requests for toys remained significant for total screen media exposure. Screen media exposure is a prospective risk factor for children's requests for advertised products. Future experimental studies on children's health- and consumer-related outcomes are warranted.

  9. The Future Is Bright and Predictable: The Development of Prospective Life Stories across Childhood and Adolescence

    ERIC Educational Resources Information Center

    Bohn, Annette; Berntsen, Dorthe

    2013-01-01

    When do children develop the ability to imagine their future lives in terms of a coherent prospective life story? We investigated whether this ability develops in parallel with the ability to construct a life story for the past and narratives about single autobiographical events in the past and future. Four groups of school children aged 9 to 15…

  10. Navigating Into the Future or Driven by the Past.

    PubMed

    Seligman, Martin E P; Railton, Peter; Baumeister, Roy F; Sripada, Chandra

    2013-03-01

    Prospection (Gilbert & Wilson, 2007), the representation of possible futures, is a ubiquitous feature of the human mind. Much psychological theory and practice, in contrast, has understood human action as determined by the past and viewed any such teleology (selection of action in light of goals) as a violation of natural law because the future cannot act on the present. Prospection involves no backward causation; rather, it is guidance not by the future itself but by present, evaluative representations of possible future states. These representations can be understood minimally as "If X, then Y" conditionals, and the process of prospection can be understood as the generation and evaluation of these conditionals. We review the history of the attempt to cast teleology out of science, culminating in the failures of behaviorism and psychoanalysis to account adequately for action without teleology. A wide range of evidence suggests that prospection is a central organizing feature of perception, cognition, affect, memory, motivation, and action. The authors speculate that prospection casts new light on why subjectivity is part of consciousness, what is "free" and "willing" in "free will," and on mental disorders and their treatment. Viewing behavior as driven by the past was a powerful framework that helped create scientific psychology, but accumulating evidence in a wide range of areas of research suggests a shift in framework, in which navigation into the future is seen as a core organizing principle of animal and human behavior. © The Author(s) 2013.

  11. Singlet-catalyzed electroweak phase transitions in the 100 TeV frontier

    NASA Astrophysics Data System (ADS)

    Kotwal, Ashutosh V.; Ramsey-Musolf, Michael J.; No, Jose Miguel; Winslow, Peter

    2016-08-01

    We study the prospects for probing a gauge singlet scalar-driven strong first-order electroweak phase transition with a future proton-proton collider in the 100 TeV range. Singlet-Higgs mixing enables resonantly enhanced di-Higgs production, potentially aiding discovery prospects. We perform Monte Carlo scans of the parameter space to identify regions associated with a strong first-order electroweak phase transition, analyze the corresponding di-Higgs signal, and select a set of benchmark points that span the range of di-Higgs signal strengths. For the b b ¯γ γ and 4 τ final states, we investigate discovery prospects for each benchmark point for the high-luminosity phase of the Large Hadron Collider and for a future p p collider with √{s }=50 , 100, or 200 TeV. We find that any of these future collider scenarios could significantly extend the reach beyond that of the high-luminosity LHC, and that with √{s }=100 TeV (200 TeV) and 30 ab-1 , the full region of parameter space favorable to strong first-order electroweak phase transitions is almost fully (fully) discoverable.

  12. Seeing light at the end of the tunnel: Positive prospective mental imagery and optimism in depression.

    PubMed

    Ji, Julie L; Holmes, Emily A; Blackwell, Simon E

    2017-01-01

    Optimism is associated with positive outcomes across many health domains, from cardiovascular disease to depression. However, we know little about cognitive processes underlying optimism in psychopathology. The present study tested whether the ability to vividly imagine positive events in one's future was associated with dispositional optimism in a sample of depressed adults. Cross-sectional and longitudinal analyses were conducted, using baseline (all participants, N=150) and follow-up data (participants in the control condition only, N=63) from a clinical trial (Blackwell et al., 2015). Vividness of positive prospective imagery, assessed on a laboratory-administered task at baseline, was significantly associated with both current optimism levels at baseline and future (seven months later) optimism levels, including when controlling for potential confounds. Even when depressed, those individuals able to envision a brighter future were more optimistic, and regained optimism more quickly over time, than those less able to do so at baseline. Strategies to increase the vividness of positive prospective imagery may aid development of mental health interventions to boost optimism. Copyright © 2016 The Authors. Published by Elsevier Ireland Ltd.. All rights reserved.

  13. Negative Prospective Memory in Alzheimer's Disease: "Do Not Perform That Action".

    PubMed

    El Haj, Mohamad; Coello, Yann; Kapogiannis, Dimitrios; Gallouj, Karim; Antoine, Pascal

    2018-01-01

    Relatively to "standard" prospective memory, i.e., remembering to perform a future action, little is known about negative prospective memory, i.e., remembering not to perform a future action. This study investigated the latter ability in Alzheimer's disease (AD). AD participants and healthy older adults were asked to click on the keyboard or not to click on it when a cue word was encountered. Results showed more omissions (i.e., forgetting to click the keyboard when the instruction was to do so) in AD participants than in healthy older adults, suggesting a prospective memory deficit. Interestingly, more commissions (i.e., clicking the keyboard when the instruction was not to do so) were also observed in AD participants than in healthy older adults. Similar levels of commissions and omissions were observed in AD participants and in healthy older adults. Also, commissions and omissions were correlated with performance on an inhibition assessment task. Our findings reveal that AD is characterized by not only difficulty in the retrieval of recent information, but also difficulty to inhibit no-longer appropriate stimulus-response associations previously learned, suggesting a specific deficit of negative prospective memory in AD.

  14. The impact of Eysenck's extraversion-introversion personality dimension on prospective memory.

    PubMed

    Heffernan, T M; Ling, J

    2001-09-01

    Prospective memory (PM) is memory for future events. PM is a developing area of research (e.g., Brandimonte, Einstein & McDaniel, 1996) with recent work linking personality types and their utilisation of PM (Goschke & Kuhl, 1996; Searleman, 1996). The present study compared 28 extraverts and 28 introverts on their short- and long-term prospective memory using the Prospective Memory Scale developed by Hannon, Adams, Harrington, Fries-Dias & Gibson (1995). The main finding was that extraverts reported significantly fewer errors on short- and long-term PM than introverts, and this difference could not be explained in terms of the number of strategies used to support prospective remembering. These findings are discussed in relation to differences between the personality types.

  15. Gilbert W. Beebe Symposium on 30 Years after the Chernobyl Accident: Current and Future Studies on Radiation Health Effects.

    PubMed

    Samet, Jonathan M; de González, Amy Berrington; Dauer, Lawrence T; Hatch, Maureen; Kosti, Ourania; Mettler, Fred A; Satyamitra, Merriline M

    2018-01-01

    This commentary summarizes the presentations and discussions from the 2016 Gilbert W. Beebe symposium "30 years after the Chernobyl accident: Current and future studies on radiation health effects." The symposium was hosted by the National Academies of Sciences, Engineering, and Medicine (the National Academies). The symposium focused on the health consequences of the Chernobyl accident, looking retrospectively at what has been learned and prospectively at potential future discoveries using emerging 21st Century research methodologies.

  16. Selective effects of acute alcohol intake on the prospective and retrospective components of a prospective-memory task with emotional targets.

    PubMed

    Walter, Nora T; Bayen, Ute J

    2016-01-01

    Prospective memory involves remembering to do something in the future and has a prospective component (remembering that something must be done) and a retrospective component (remembering what must be done and when it must be done). Initial studies reported an impairment in prospective-memory performance due to acute alcohol consumption. Retrospective-memory studies demonstrated that alcohol effects vary depending on the emotionality of the information that needs to be learned. The aim of the present study was to investigate possible differential effects of a mild acute alcohol dose (0.4 g/kg) on the prospective and retrospective components of prospective memory depending on cue valence. Seventy-five participants were allocated to an alcohol or placebo group and performed a prospective-memory task in which prospective-memory cue valence was manipulated (negative, neutral, positive). The multinomial model of event-based prospective memory (Smith and Bayen 2004) was used to measure alcohol and valence effects on the two prospective-memory components separately. Overall, no main effect of alcohol or valence on prospective-memory performance occurred. However, model-based analyses demonstrated a significantly higher retrospective component for positive compared with negative cues in the placebo group. In the alcohol group, the prospective component was weaker for negative than for neutral cues and the retrospective component was stronger for positive than for neutral cues. Group comparisons showed that the alcohol group had a significantly lower prospective component for negative cues and a lower retrospective component for neutral cues. This is the first study to demonstrate selective alcohol effects on prospective-memory components depending on prospective-memory cue valence.

  17. Prospective memory impairment in "ecstasy" (MDMA) users.

    PubMed

    Rendell, Peter G; Gray, Timothy J; Henry, Julie D; Tolan, Anne

    2007-11-01

    Considerable research indicates that "ecstasy" users perceive their memory for future intentions (prospective memory) to be impaired. However, only one empirical study to date has directly tested how this capacity is affected by ecstasy use, and this study provided relatively limited information regarding the extent, scope, or implications of problems experienced. The present study assessed prospective performance on a laboratory measure of prospective memory that closely represents the types of prospective memory tasks that actually occur in everyday life and provides an opportunity to investigate the different sorts of prospective memory failures that occur ("Virtual Week"). Ecstasy user group (27 current users and 34 nonusers) was between participants, and prospective memory task (regular, irregular, time-check) was within participants. A measure sensitive to specific aspects of psychopathology was also administered. Ecstasy users were significantly impaired on Virtual Week, and these deficits were of a comparable magnitude irrespective of the specific prospective memory task demands. The pattern of results was unchanged after controlling for marijuana use, level of psychopathology, and sleep quality. Further, prospective memory was shown to be significantly impaired for both relatively infrequent and relatively frequent ecstasy users, although for the latter group the magnitude of this deficit was greater. Prospective memory performance is sensitive to regular and even moderate ecstasy use. Importantly, ecstasy users experience generalized difficulties with prospective memory, suggesting that these deficits are likely to have important implications for day-to-day functioning.

  18. Episodic Future Thinking: Mechanisms and Functions.

    PubMed

    Schacter, Daniel L; Benoit, Roland G; Szpunar, Karl K

    2017-10-01

    Episodic future thinking refers to the capacity to imagine or simulate experiences that might occur in one's personal future. Cognitive, neuropsychological, and neuroimaging research concerning episodic future thinking has accelerated during recent years. This article discusses research that has delineated cognitive and neural mechanisms that support episodic future thinking as well as the functions that episodic future thinking serves. Studies focused on mechanisms have identified a core brain network that underlies episodic future thinking and have begun to tease apart the relative contributions of particular regions in this network, and the specific cognitive processes that they support. Studies concerned with functions have identified several domains in which episodic future thinking produces performance benefits, including decision making, emotion regulation, prospective memory, and spatial navigation.

  19. Prospective associations between prosocial behavior and social dominance in early childhood: are sharers the best leaders?

    PubMed

    Ostrov, Jamie M; Guzzo, Jamie L

    2015-01-01

    A short-term longitudinal study during early childhood (N = 96; M = 42.80; SD = 7.57) investigated the concurrent and prospective association between prosocial behavior and social dominance. Time-intensive school-based focal child sampling with continuous recording observations of prosocial behavior to peers were conducted and teacher-reports of social dominance were collected. The study documents significant prospective links between prosocial behavior to peers and increases in social dominance over time. Social dominance was not associated with changes in prosocial behavior. The findings extend past empirical work in early childhood and future directions are discussed.

  20. Predictors of Future Expectations of Inner-City Children: A 9-Month Prospective Study.

    ERIC Educational Resources Information Center

    Dubow, Eric F.; Arnett, Mitzi; Smith, Katherine; Ippolito, Maria F.

    2001-01-01

    Assessed contributions of internal resources, supportive family and peer relations, peer negative influences, and behavioral adjustment to positive expectations for the future for inner-city school children. Found that higher levels of positive expectation related to lower levels of problem behavior and to higher levels of school involvement,…

  1. Prospective memory in schizophrenia: Relationship to medication management skills, neurocognition and symptoms in individuals with schizophrenia

    PubMed Central

    Raskin, S.; Maye, J.; Rogers, A.; Correll, D.; Zamroziewicz, M.; Kurtz, M.

    2014-01-01

    Objective Impaired adherence to medication regimens is a serious concern for individuals with schizophrenia linked to relapse and poorer outcomes. One possible reason for poor adherence to medication is poor ability to remember future intentions, labeled prospective memory skills. It has been demonstrated in several studies that individuals with schizophrenia have impairments in prospective memory that are linked to everyday life skills. However, there have been no studies, to our knowledge, examining the relationship of a clinical measure of prospective memory to medication management skills, a key element of successful adherence. Methods In this study 41 individuals with schizophrenia and 25 healthy adults were administered a standardized test battery that included measures of prospective memory, medication management skills, neurocognition and symptoms. Results Individuals with schizophrenia demonstrated impairments in prospective memory (both time and event-based) relative to healthy controls. Performance on the test of prospective memory was correlated with the standardized measure of medication management in individuals with schizophrenia. Moreover, the test of prospective memory predicted skills in medication adherence even after measures of neurocognition were accounted for. Conclusions This suggests that prospective memory may play a key role in medication management skills and thus should be a target of cognitive remediation programs. PMID:24188118

  2. Potential and prospective implementation of carbon nanotubes on next generation aircraft and space vehicles: A review of current and expected applications in aerospace sciences

    NASA Astrophysics Data System (ADS)

    Gohardani, Omid; Elola, Maialen Chapartegui; Elizetxea, Cristina

    2014-10-01

    Carbon nanotubes have instigated the interest of many different scientific fields since their authenticated introduction, more than two decades ago. Particularly in aerospace applications, the potential implementations of these advanced materials have been predicted to have a large impact on future aircraft and space vehicles, mainly due to their distinct features, which include superior mechanical, thermal and electrical properties. This article provides the very first consolidated review of the imminent prospects of utilizing carbon nanotubes and nanoparticles in aerospace sciences, based on their recent implementations and predicted future applications. Explicitly, expected carbon nanotube employment in aeronautics and astronautics are identified for commercial aircraft, military aircraft, rotorcraft, unmanned aerial vehicles, satellites, and space launch vehicles. Attention is devoted to future utilization of carbon nanotubes, which may comprise hydrogen storage encapsulation, composite material implementation, lightning protection for aircraft, aircraft icing mitigation, reduced weight of airframes/satellites, and alleviation of challenges related to future space launch. This study further sheds light onto recent actualized implementations of carbon nanotubes in aerospace applications, as well as current and prospective challenges related to their usage in aerospace sciences, encompassing health and safety hazards, large scale manufacturing, achievement of optimum properties, recycling, and environmental impacts.

  3. The Relationship between Learning Approaches of Prospective Teachers and Their Academic Achievement

    ERIC Educational Resources Information Center

    Gurlen, Eda; Turan, Sevgi; Senemoglu, Nuray

    2013-01-01

    To prepare for future professional challenges, prospective teachers should acquire the capabilities for independent learning. Prospective teachers should know how to learn effectively. In this article, prospective teachers' learning approaches, learning preference and the relationship between learning preference, learning approaches with…

  4. Full-Time Non-Tenure-Track Faculty: Current Status, Future Prospects, Remaining Research Questions. ASHE Annual Meeting Paper.

    ERIC Educational Resources Information Center

    Chronister, Jay L.; And Others

    This study used available data to develop an initial profile of non-tenure-track (NTT) faculty in comparison to their non-tenured but tenure track (TT) counterparts and to develop questions to guide future study of this group. Using data from a 1989 survey of the professorate conducted by the Carnegie Foundation for the Advancement of Teaching,…

  5. Prospective Reciprocal Relations between Physical Activity and Depression in Female Adolescents

    ERIC Educational Resources Information Center

    Jerstad, Sarah J.; Boutelle, Kerri N.; Ness, Kirsten K.; Stice, Eric

    2010-01-01

    Objective: Although an inverse correlation between physical activity and depression among adolescents has been found in research, this relation has seldom been examined prospectively. Thus, we tested whether physical activity reduces risk for future escalations in depression and whether depression decreases likelihood of future change in physical…

  6. The Electronic Age and Libraries: Present Problems and Future Prospects.

    ERIC Educational Resources Information Center

    Igwe, P. O. E.

    1986-01-01

    Summarizes impact of the electronic age and role of the library focusing on the situation in Nigeria and concern for the new age; problems of Nigerian libraries and librarians (developing economy, responsibility for development, political situation, technological problems, lack of personnel); future prospects; and suggestions for present.…

  7. The UAE healthy future study: a pilot for a prospective cohort study of 20,000 United Arab Emirates nationals.

    PubMed

    Abdulle, Abdishakur; Alnaeemi, Abdullah; Aljunaibi, Abdullah; Al Ali, Abdulrahman; Al Saedi, Khaled; Al Zaabi, Eiman; Oumeziane, Naima; Al Bastaki, Marina; Al-Houqani, Mohammed; Al Maskari, Fatma; Al Dhaheri, Ayesha; Shah, Syed M; Loney, Tom; El-Sadig, Mohamed; Oulhaj, Abderrahim; Wareth, Leila Abdel; Al Mahmeed, Wael; Alsafar, Habiba; Hirsch, Benjamin; Al Anouti, Fatme; Yaaqoub, Jamila; Inman, Claire K; Al Hamiz, Aisha; Al Hosani, Ayesha; Haji, Muna; Alsharid, Teeb; Al Zaabi, Thekra; Al Maisary, Fatima; Galani, Divya; Sprosen, Tim; El Shahawy, Omar; Ahn, Jiyoung; Kirchhoff, Tomas; Ramasamy, Ravichandran; Schmidt, Ann Marie; Hayes, Richard; Sherman, Scott; Ali, Raghib

    2018-01-05

    The United Arab Emirates (UAE) is faced with a rapidly increasing burden of non-communicable diseases including obesity, diabetes, and cardiovascular disease. The UAE Healthy Future study is a prospective cohort designed to identify associations between risk factors and these diseases amongst Emiratis. The study will enroll 20,000 UAE nationals aged ≥18 years. Environmental and genetic risk factors will be characterized and participants will be followed for future disease events. As this was the first time a prospective cohort study was being planned in the UAE, a pilot study was conducted in 2015 with the primary aim of establishing the feasibility of conducting the study. Other objectives were to evaluate the implementation of the main study protocols, and to build adequate capacity to conduct advanced clinical laboratory analyses. Seven hundred sixty nine UAE nationals aged ≥18 years were invited to participate voluntarily in the pilot study. Participants signed an informed consent, completed a detailed questionnaire, provided random blood, urine, and mouthwash samples and were assessed for a series of clinical measures. All specimens were transported to the New York University Abu Dhabi laboratories where samples were processed and analyzed for routine chemistry and hematology. Plasma, serum, and a small whole blood sample for DNA extraction were aliquoted and stored at -80 °C for future analyses. Overall, 517 Emirati men and women agreed to participate (68% response rate). Of the total participants, 495 (95.0%), 430 (82.2%), and 492 (94.4%), completed the questionnaire, physical measurements, and provided biological samples, respectively. The pilot study demonstrated the feasibility of recruitment and completion of the study protocols for the first large-scale cohort study designed to identify emerging risk factors for the major non-communicable diseases in the region.

  8. Time-based and event-based prospective memory in autism spectrum disorder: the roles of executive function and theory of mind, and time-estimation.

    PubMed

    Williams, David; Boucher, Jill; Lind, Sophie; Jarrold, Christopher

    2013-07-01

    Prospective memory (remembering to carry out an action in the future) has been studied relatively little in ASD. We explored time-based (carry out an action at a pre-specified time) and event-based (carry out an action upon the occurrence of a pre-specified event) prospective memory, as well as possible cognitive correlates, among 21 intellectually high-functioning children with ASD, and 21 age- and IQ-matched neurotypical comparison children. We found impaired time-based, but undiminished event-based, prospective memory among children with ASD. In the ASD group, time-based prospective memory performance was associated significantly with diminished theory of mind, but not with diminished cognitive flexibility. There was no evidence that time-estimation ability contributed to time-based prospective memory impairment in ASD.

  9. Sleep Improves Prospective Remembering by Facilitating Spontaneous-Associative Retrieval Processes

    PubMed Central

    Diekelmann, Susanne; Wilhelm, Ines; Wagner, Ullrich; Born, Jan

    2013-01-01

    Memories are of the past but for the future, enabling individuals to implement intended plans and actions at the appropriate time. Prospective memory is the specific ability to remember and execute an intended behavior at some designated point in the future. Although sleep is well-known to benefit the consolidation of memories for past events, its role for prospective memory is still not well understood. Here, we show that sleep as compared to wakefulness after prospective memory instruction enhanced the successful execution of prospective memories two days later. We further show that sleep benefited both components of prospective memory, i.e. to remember that something has to be done (prospective component) and to remember what has to be done (retrospective component). Finally, sleep enhanced prospective remembering particularly when attentional resources were reduced during task execution, suggesting that subjects after sleep were able to recruit additional spontaneous-associative retrieval processes to remember intentions successfully. Our findings indicate that sleep supports the maintenance of prospective memory over time by strengthening intentional memory representations, thus favoring the spontaneous retrieval of the intended action at the appropriate time. PMID:24143246

  10. A critical evaluation of the validity of episodic future thinking: A clinical neuropsychology perspective.

    PubMed

    Ward, Amanda M

    2016-11-01

    Episodic future thinking is defined as the ability to mentally simulate a future event. Although episodic future thinking has been studied extensively in neuroscience, this construct has not been explored in depth from the perspective of clinical neuropsychology. The aim of this critical narrative review is to assess the validity and clinical implications of episodic future thinking. A systematic review of episodic future thinking literature was conducted. PubMed and PsycInfo were searched through July 2015 for review and empirical articles with the following search terms: "episodic future thinking," "future mental simulation," "imagining the future," "imagining new experiences," "future mental time travel," "future autobiographical experience," and "prospection." The review discusses evidence that episodic future thinking is important for adaptive functioning, which has implications for neurological populations. To determine the validity of episodic future thinking, the construct is evaluated with respect to related constructs, such as imagination, episodic memory, autobiographical memory, prospective memory, narrative construction, and working memory. Although it has been minimally investigated, there is evidence of convergent and discriminant validity for episodic future thinking. Research has not addressed the incremental validity of episodic future thinking. Practical considerations of episodic future thinking tasks and related constructs in a clinical neuropsychological setting are considered. The utility of episodic future thinking is currently unknown due to the lack of research investigating the validity of episodic future thinking. Future work is discussed, which could determine whether episodic future thinking is an important missing piece in standard clinical neuropsychological assessment. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  11. The physics of proton antiproton collisions

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shochet, M.

    1991-12-03

    This paper contains information information on: accelerator and detector; QCD studies; studies of the electroweak force; The search for the top quark; {beta} physics at hadron colliders; and the search for exotic objects and prospects for the future.

  12. What are the health benefits of active travel? A systematic review of trials and cohort studies.

    PubMed

    Saunders, Lucinda E; Green, Judith M; Petticrew, Mark P; Steinbach, Rebecca; Roberts, Helen

    2013-01-01

    Increasing active travel (primarily walking and cycling) has been widely advocated for reducing obesity levels and achieving other population health benefits. However, the strength of evidence underpinning this strategy is unclear. This study aimed to assess the evidence that active travel has significant health benefits. The study design was a systematic review of (i) non-randomised and randomised controlled trials, and (ii) prospective observational studies examining either (a) the effects of interventions to promote active travel or (b) the association between active travel and health outcomes. Reports of studies were identified by searching 11 electronic databases, websites, reference lists and papers identified by experts in the field. Prospective observational and intervention studies measuring any health outcome of active travel in the general population were included. Studies of patient groups were excluded. Twenty-four studies from 12 countries were included, of which six were studies conducted with children. Five studies evaluated active travel interventions. Nineteen were prospective cohort studies which did not evaluate the impact of a specific intervention. No studies were identified with obesity as an outcome in adults; one of five prospective cohort studies in children found an association between obesity and active travel. Small positive effects on other health outcomes were found in five intervention studies, but these were all at risk of selection bias. Modest benefits for other health outcomes were identified in five prospective studies. There is suggestive evidence that active travel may have a positive effect on diabetes prevention, which may be an important area for future research. Active travel may have positive effects on health outcomes, but there is little robust evidence to date of the effectiveness of active transport interventions for reducing obesity. Future evaluations of such interventions should include an assessment of their impacts on obesity and other health outcomes.

  13. What Are the Health Benefits of Active Travel? A Systematic Review of Trials and Cohort Studies

    PubMed Central

    Saunders, Lucinda E.; Green, Judith M.; Petticrew, Mark P.; Steinbach, Rebecca; Roberts, Helen

    2013-01-01

    Background Increasing active travel (primarily walking and cycling) has been widely advocated for reducing obesity levels and achieving other population health benefits. However, the strength of evidence underpinning this strategy is unclear. This study aimed to assess the evidence that active travel has significant health benefits. Methods The study design was a systematic review of (i) non-randomised and randomised controlled trials, and (ii) prospective observational studies examining either (a) the effects of interventions to promote active travel or (b) the association between active travel and health outcomes. Reports of studies were identified by searching 11 electronic databases, websites, reference lists and papers identified by experts in the field. Prospective observational and intervention studies measuring any health outcome of active travel in the general population were included. Studies of patient groups were excluded. Results Twenty-four studies from 12 countries were included, of which six were studies conducted with children. Five studies evaluated active travel interventions. Nineteen were prospective cohort studies which did not evaluate the impact of a specific intervention. No studies were identified with obesity as an outcome in adults; one of five prospective cohort studies in children found an association between obesity and active travel. Small positive effects on other health outcomes were found in five intervention studies, but these were all at risk of selection bias. Modest benefits for other health outcomes were identified in five prospective studies. There is suggestive evidence that active travel may have a positive effect on diabetes prevention, which may be an important area for future research. Conclusions Active travel may have positive effects on health outcomes, but there is little robust evidence to date of the effectiveness of active transport interventions for reducing obesity. Future evaluations of such interventions should include an assessment of their impacts on obesity and other health outcomes. PMID:23967064

  14. An extended PROSPECT: Advance in the leaf optical properties model separating total chlorophylls into chlorophyll a and b.

    PubMed

    Zhang, Yao; Huang, Jingfeng; Wang, Fumin; Blackburn, George Alan; Zhang, Hankui K; Wang, Xiuzhen; Wei, Chuanwen; Zhang, Kangyu; Wei, Chen

    2017-07-25

    The PROSPECT leaf optical model has, to date, well-separated the effects of total chlorophyll and carotenoids on leaf reflectance and transmittance in the 400-800 nm. Considering variations in chlorophyll a:b ratio with leaf age and physiological stress, a further separation of total plant-based chlorophylls into chlorophyll a and chlorophyll b is necessary for advanced monitoring of plant growth. In this study, we present an extended version of PROSPECT model (hereafter referred to as PROSPECT-MP) that can combine the effects of chlorophyll a, chlorophyll b and carotenoids on leaf directional hemispherical reflectance and transmittance (DHR and DHT) in the 400-800 nm. The LOPEX93 dataset was used to evaluate the capabilities of PROSPECT-MP for spectra modelling and pigment retrieval. The results show that PROSPECT-MP can both simultaneously retrieve leaf chlorophyll a and b, and also performs better than PROSPECT-5 in retrieving carotenoids concentrations. As for the simulation of DHR and DHT, the performances of PROSPECT-MP are similar to that of PROSPECT-5. This study demonstrates the potential of PROSPECT-MP for improving capabilities of remote sensing of leaf photosynthetic pigments (chlorophyll a, chlorophyll b and carotenoids) and for providing a framework for future refinements in the modelling of leaf optical properties.

  15. Neutrino Phenomenology: Highlights of Oscillation Results and Future Prospects

    NASA Astrophysics Data System (ADS)

    Goswami, Srubabati

    2016-04-01

    In this talk the current status of neutrino oscillation parameters are presented. The prospects of determination of neutrino mass hierarchy, octant of θ23 and the CP phase δCP in future long-baseline and atmospheric experiments are reviewed. The impact of precision measurement of oscillation parameters on neutrino mass models are also discussed.

  16. The Life and Professional Prospects of Future Specialists of Agricultural Production

    ERIC Educational Resources Information Center

    Khovalyg, N.; Kendivan, O.

    2006-01-01

    This article reports the findings of a survey examining the social and psychological characteristics of future specialists of agriculture who were enrolled as students in Tuva State University. The study was carried out by the Tuva State Institute for Cadre Retraining and Upgrading of Qualifications under the Government of the Republic of Tuva.…

  17. Health psychology in Ghana: A review of the multidisciplinary origins of a young sub-field and its future prospects.

    PubMed

    de-Graft Aikins, Ama

    2018-03-01

    This article presents a historical overview of psychology applied to health and health psychology in Ghana. A brief history of health, illness and healthcare in Ghana is introduced. Then, the history of psychology in Ghana is presented, with signposts of the major turns in the field in relation to psychology and other disciplines applied to health and the emergence of health psychology as a sub-field. Selected health psychology studies are reviewed to highlight ideological trends in the field. Finally, future prospects are considered in terms of how the sub-field can transition into an established critical field with unique contributions to make to global health psychology.

  18. A Meta-Analysis and Critical Review of Prospective Memory in Autism Spectrum Disorder

    ERIC Educational Resources Information Center

    Landsiedel, Julia; Williams, David M.; Abbot-Smith, Kirsten

    2017-01-01

    Prospective memory (PM) is the ability to remember to carry out a planned intention at an appropriate moment in the future. Research on PM in ASD has produced mixed results. We aimed to establish the extent to which two types of PM (event-based/time-based) are impaired in ASD. In part 1, a meta-analysis of all existing studies indicates a large…

  19. When Antimicrobial Stewardship Isn′t Watching: The Educational Impact of Critical Care Prospective Audit and Feedback

    PubMed Central

    Fleming, Dimitra; Ali, Karim F.; Matelski, John; D'Sa, Ryan; Powis, Jeff

    2016-01-01

    Prospective audit and feedback (PAF) is an effective strategy to optimize antimicrobial use in the critical care setting, yet whether skills gained during PAF influence future antimicrobial prescribing is uncertain. This multisite study demonstrates that knowledge learned during PAF is translated and incorporated into the practice of critical care physicians even when not supported by an antimicrobial stewardship program. PMID:27382599

  20. The Future Orientation of Past Memory: The Role of BA 10 in Prospective and Retrospective Retrieval Modes.

    PubMed

    Underwood, Adam G; Guynn, Melissa J; Cohen, Anna-Lisa

    2015-01-01

    Klein made the provocative suggestion that the purpose of human episodic memory is to enable individuals to plan and prepare for the future. In other words, although episodic (retrospective) memory is about the past, it is not actually for the past; it is for the future. Within this focus, a natural subject for investigation is prospective memory, or memory to do things in the future. An important theoretical construct in the fields of both retrospective memory and prospective memory is that of a retrieval mode, or a neurocognitive set or readiness to treat environmental stimuli as potential retrieval cues. This construct was originally introduced in a theory of episodic (retrospective) memory and has more recently been invoked in a theory of how some prospective memory tasks are accomplished. To our knowledge, this construct has not been explicitly compared between the two literatures, and thus this is the purpose of the present article. Although we address the behavioral evidence for each construct, our primary goal is to assess the extent to which each retrieval mode appears to rely on a common neural region. Our review highlights the fact that a particular area of prefrontal cortex (BA 10) appears to play an important role in both retrospective and prospective retrieval modes. We suggest, based on this evidence and these ideas, that prospective memory research could profit from more active exploration of the relevance of theoretical constructs from the retrospective memory literature.

  1. The Future Orientation of Past Memory: The Role of BA 10 in Prospective and Retrospective Retrieval Modes

    PubMed Central

    Underwood, Adam G.; Guynn, Melissa J.; Cohen, Anna-Lisa

    2015-01-01

    Klein made the provocative suggestion that the purpose of human episodic memory is to enable individuals to plan and prepare for the future. In other words, although episodic (retrospective) memory is about the past, it is not actually for the past; it is for the future. Within this focus, a natural subject for investigation is prospective memory, or memory to do things in the future. An important theoretical construct in the fields of both retrospective memory and prospective memory is that of a retrieval mode, or a neurocognitive set or readiness to treat environmental stimuli as potential retrieval cues. This construct was originally introduced in a theory of episodic (retrospective) memory and has more recently been invoked in a theory of how some prospective memory tasks are accomplished. To our knowledge, this construct has not been explicitly compared between the two literatures, and thus this is the purpose of the present article. Although we address the behavioral evidence for each construct, our primary goal is to assess the extent to which each retrieval mode appears to rely on a common neural region. Our review highlights the fact that a particular area of prefrontal cortex (BA 10) appears to play an important role in both retrospective and prospective retrieval modes. We suggest, based on this evidence and these ideas, that prospective memory research could profit from more active exploration of the relevance of theoretical constructs from the retrospective memory literature. PMID:26733844

  2. Singlet-catalyzed electroweak phase transitions in the 100 TeV frontier

    DOE PAGES

    Kotwal, Ashutosh V.; Ramsey-Musolf, Michael J.; No, Jose Miguel; ...

    2016-08-23

    We study the prospects for probing a gauge singlet scalar-driven strong first-order electroweak phase transition with a future proton-proton collider in the 100 TeV range. Singlet-Higgs mixing enables resonantly enhanced di-Higgs production, potentially aiding discovery prospects. We perform Monte Carlo scans of the parameter space to identify regions associated with a strong first-order electroweak phase transition, analyze the corresponding di-Higgs signal, and select a set of benchmark points that span the range of di-Higgs signal strengths. For the bmore » $$\\bar{b}$$γγ and 4τ final states, we investigate discovery prospects for each benchmark point for the high-luminosity phase of the Large Hadron Collider and for a future pp collider with s=50, 100, or 200 TeV. We find that any of these future collider scenarios could significantly extend the reach beyond that of the high-luminosity LHC, and that with s=100 TeV (200 TeV) and 30 ab -1, the full region of parameter space favorable to strong first-order electroweak phase transitions is almost fully (fully) discoverable.« less

  3. A Multinomial Model of Event-Based Prospective Memory

    ERIC Educational Resources Information Center

    Smith, Rebekah E.; Bayen, Ute J.

    2004-01-01

    Prospective memory is remembering to perform an action in the future. The authors introduce the 1st formal model of event-based prospective memory, namely, a multinomial model that includes 2 separate parameters related to prospective memory processes. The 1st measures preparatory attentional processes, and the 2nd measures retrospective memory…

  4. Supporting global health goals with information and communications technology

    PubMed Central

    Boman, Magnus; Kruse, Erik

    2017-01-01

    ABSTRACT The objective of this study is to critically assess the possible roles of information and communications technology (ICT) in supporting global health goals. This is done by considering privilege and connectibility. In short, ICT can contribute by providing health information via four different kinds of access, each with its own history and prospective future. All four are analyzed here, in two perspectives: business-as-usual and disruptive. Health data analytics is difficult since the digital representation of past, current, and future health information is lacking. The flow of analytics that may prove beneficial to the individual and not just meet abstract population-level goals or ambitions is analyzed in detail. Sensemaking is also needed, to meet the minimum requirement of making prospective future services understandable to policymakers. Drivers as well as barriers for areas in which policy decisions have the potential to drive positive developments for meeting the Sustainable Development Goals are identified. PMID:28838300

  5. Supporting global health goals with information and communications technology.

    PubMed

    Boman, Magnus; Kruse, Erik

    2017-06-01

    The objective of this study is to critically assess the possible roles of information and communications technology (ICT) in supporting global health goals. This is done by considering privilege and connectibility. In short, ICT can contribute by providing health information via four different kinds of access, each with its own history and prospective future. All four are analyzed here, in two perspectives: business-as-usual and disruptive. Health data analytics is difficult since the digital representation of past, current, and future health information is lacking. The flow of analytics that may prove beneficial to the individual and not just meet abstract population-level goals or ambitions is analyzed in detail. Sensemaking is also needed, to meet the minimum requirement of making prospective future services understandable to policymakers. Drivers as well as barriers for areas in which policy decisions have the potential to drive positive developments for meeting the Sustainable Development Goals are identified.

  6. A Curriculum for the New Dental Practitioner: Preparing Dentists for a Prospective Oral Health Care Environment

    PubMed Central

    Polverini, Peter J.

    2012-01-01

    The emerging concept of prospective health care would shift the focus of health care from disease management to disease prevention and health management. Dentistry has a unique opportunity to embrace this model of prospective and collaborative care and focus on the management of oral health. Academic dentistry must better prepare future dentists to succeed in this new health care environment by providing them with the scientific and technical knowledge required to understand and assess risk and practice disease prevention. Dental schools must consider creating career pathways for enabling future graduates to assume important leadership roles that will advance a prospective oral health care system. PMID:22390456

  7. Prospective Teachers' Ideas about Teacher Recruitment and Their Professional Future

    ERIC Educational Resources Information Center

    Sahin, Idris

    2011-01-01

    This research aimed to reveal how prospective teachers viewed their professional future and to discern how their lives would be affected in case they were not recruited as teachers. The research was conducted on senior students at Buca Faculty of Education. The sample of the research consisted of 149 senior students, including 82 girls and 67…

  8. The Effect of the Time of Injection of Intrathecal Analgesia on the Length of Early and Advanced Labor

    DTIC Science & Technology

    2000-01-03

    drug combinations. Intrathecal Analgesia 36 Future Studies Recommendations for future studies include a prospective randomized clinical trial to examine...second stages of labor because of the variations in client population and in clinical practice. Friedman (1978) Intrathecal Analgesia 7 however, does...that the administration of morphine into the subarchnoid space of rats produced potent analgesia (Wang, 1977). These effects were then clinically applied

  9. Imagining a brighter future: the effect of positive imagery training on mood, prospective mental imagery and emotional bias in older adults.

    PubMed

    Murphy, Susannah E; Clare O'Donoghue, M; Drazich, Erin H S; Blackwell, Simon E; Christina Nobre, Anna; Holmes, Emily A

    2015-11-30

    Positive affect and optimism play an important role in healthy ageing and are associated with improved physical and cognitive health outcomes. This study investigated whether it is possible to boost positive affect and associated positive biases in this age group using cognitive training. The effect of computerised imagery-based cognitive bias modification on positive affect, vividness of positive prospective imagery and interpretation biases in older adults was measured. 77 older adults received 4 weeks (12 sessions) of imagery cognitive bias modification or a control condition. They were assessed at baseline, post-training and at a one-month follow-up. Both groups reported decreased negative affect and trait anxiety, and increased optimism across the three assessments. Imagery cognitive bias modification significantly increased the vividness of positive prospective imagery post-training, compared with the control training. Contrary to our hypothesis, there was no difference between the training groups in negative interpretation bias. This is a useful demonstration that it is possible to successfully engage older adults in computer-based cognitive training and to enhance the vividness of positive imagery about the future in this group. Future studies are needed to assess the longer-term consequences of such training and the impact on affect and wellbeing in more vulnerable groups. Copyright © 2015 The Authors. Published by Elsevier Ireland Ltd.. All rights reserved.

  10. Exploring prospective secondary science teachers' understandings of scientific inquiry and Mendelian genetics concepts using computer simulation

    NASA Astrophysics Data System (ADS)

    Cakir, Mustafa

    The primary objective of this case study was to examine prospective secondary science teachers' developing understanding of scientific inquiry and Mendelian genetics. A computer simulation of basic Mendelian inheritance processes (Catlab) was used in combination with small-group discussions and other instructional scaffolds to enhance prospective science teachers' understandings. The theoretical background for this research is derived from a social constructivist perspective. Structuring scientific inquiry as investigation to develop explanations presents meaningful context for the enhancement of inquiry abilities and understanding of the science content. The context of the study was a teaching and learning course focused on inquiry and technology. Twelve prospective science teachers participated in this study. Multiple data sources included pre- and post-module questionnaires of participants' view of scientific inquiry, pre-posttests of understandings of Mendelian concepts, inquiry project reports, class presentations, process videotapes of participants interacting with the simulation, and semi-structured interviews. Seven selected prospective science teachers participated in in-depth interviews. Findings suggest that while studying important concepts in science, carefully designed inquiry experiences can help prospective science teachers to develop an understanding about the types of questions scientists in that field ask, the methodological and epistemological issues that constrain their pursuit of answers to those questions, and the ways in which they construct and share their explanations. Key findings included prospective teachers' initial limited abilities to create evidence-based arguments, their hesitancy to include inquiry in their future teaching, and the impact of collaboration on thinking. Prior to this experience the prospective teachers held uninformed views of scientific inquiry. After the module, participants demonstrated extended expertise in their understandings of following aspects of scientific inquiry: (a) the iterative nature of scientific inquiry; (b) the tentativeness of specific knowledge claims; (c) the degree to which scientists rely on empirical data, as well as broader conceptual and metaphysical commitments, to assess models and to direct future inquiries; (d) the need for conceptual consistency; (e) multiple methods of investigations and multiple interpretations of data; and (f) social and cultural aspects of scientific inquiry. This research provided evidence that hypothesis testing can support the integrated acquisition of conceptual and procedural knowledge in science. Participants' conceptual elaborations of Mendelian inheritance were enhanced. There were qualitative changes in the nature of the participants' explanations. Moreover, the average percentage of correct responses improved from 39% on the pretest to 67% on the posttest. Findings also suggest those prospective science teachers' experiences as learners of science in their methods course served as a powerful tool for thinking about the role of inquiry in teaching and learning science. They had mixed views about enacting inquiry in their teaching in the future. All of them stated some kind of general willingness to do so; yet, they also mentioned some reservations and practical considerations about inquiry-based teaching.

  11. Prediction of future falls in a community dwelling older adult population using instrumented balance and gait analysis.

    PubMed

    Bauer, C M; Gröger, I; Rupprecht, R; Marcar, V L; Gaßmann, K G

    2016-04-01

    The role of instrumented balance and gait assessment when screening for prospective fallers is currently a topic of controversial discussion. This study analyzed the association between variables derived from static posturography, instrumented gait analysis and clinical assessments with the occurrence of prospective falls in a sample of community dwelling older people. In this study 84 older people were analyzed. Based on a prospective occurrence of falls, participants were categorized into fallers and non-fallers. Variables derived from clinical assessments, static posturography and instrumented gait analysis were evaluated with respect to the association with the occurrence of prospective falls using a forward stepwise, binary, logistic regression procedure. Fallers displayed a significantly shorter single support time during walking while counting backwards, increased mediolateral to anteroposterior sway amplitude ratio, increased fast mediolateral oscillations and a larger coefficient (Coeff) of sway direction during various static posturography tests. Previous falls were insignificantly associated with the occurrence of prospective falls. Variables derived from posturography and instrumented gait analysis showed significant associations with the occurrence of prospective falls in a sample of community dwelling older adults.

  12. Electrophysiological evidence during episodic prospection implicates medial prefrontal and bilateral middle temporal gyrus.

    PubMed

    Hsu, Chia-Fen; Sonuga-Barke, Edmund J S

    2016-08-01

    fMRI studies have implicated the medial prefrontal cortex and medial temporal lobe, components of the default mode network (DMN), in episodic prospection. This study compared quantitative EEG localized to these DMN regions during prospection and during resting and while waiting for rewards. EEG was recorded in twenty-two adults while they were asked to (i) envision future monetary episodes; (ii) wait for rewards and (iii) rest. Activation sources were localized to core DMN regions. EEG power and phase coherence were compared across conditions. Prospection, compared to resting and waiting, was associated with reduced power in the medial prefrontal gyrus and increased power in the bilateral medial temporal gyrus across frequency bands as well as greater phase synchrony between these regions in the delta band. The current quantitative EEG analysis confirms prior fMRI research suggesting that medial prefrontal and medial temporal gyrus interactions are central to the capacity for episodic prospection. Copyright © 2016 Elsevier B.V. All rights reserved.

  13. Prospective associations between loneliness and emotional intelligence.

    PubMed

    Wols, A; Scholte, R H J; Qualter, P

    2015-02-01

    Loneliness has been linked cross-sectionally to emotional skill deficits (e.g., Zysberg, 2012), but missing from the literature is a longitudinal examination of these relationships. The present study fills that gap by examining the prospective relationships between loneliness and emotional functioning in young adolescents in England. One hundred and ninety-six adolescents aged 11-13 years (90 females) took part in the study and completed the youth version of the Mayer-Salovey-Caruso Emotional Intelligence Test (MSCEIT-YV) and the peer-related subscale of the Loneliness and Aloneness Scale for Children and Adolescents (LACA) at two time points, which were 10 months apart. Prospective associations were obtained for male and female adolescents separately using cross-lagged statistical techniques. Our results showed prospective links between understanding and managing emotions and loneliness for both females and males. Perceiving and using emotions were prospectively linked to loneliness in males only. Possible explanations and directions for future research are discussed. Copyright © 2014 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

  14. Been there before? Examining "familiarity" as a moderator for discriminating between true and false intentions.

    PubMed

    Knieps, Melanie; Granhag, Pär A; Vrij, Aldert

    2014-01-01

    Prospection is thinking about possible future states of the world. Commitment to perform a future action-commonly referred to as intention-is a specific type of prospection. This knowledge is relevant when trying to assess whether a stated intention is a lie or the truth. An important observation is that thinking of, and committing to, future actions often evoke vivid and detailed mental images. One factor that affects how specific a person experiences these simulations is location-familiarity. The purpose of this study was to examine to what extent location-familiarity moderates how liars and truth tellers describe a mental image in an investigative interview. Liars were instructed to plan a criminal act and truth tellers were instructed to plan a non-criminal act. Before they could carry out these acts, the participants were intercepted and interviewed about the mental images they may have had experienced in this planning phase. Truth tellers told the truth whereas liars used a cover story to mask their criminal intentions. As predicted, the results showed that the truth tellers reported a mental image significantly more often than the liars. If a mental image was reported, the content of the descriptions did not differ between liars and truth tellers. In a post interview questionnaire, the participants rated the vividness (i.e., content and clarity) of their mental images. The ratings revealed that the truth tellers had experienced their mental images more vividly during the planning phase than the liars. In conclusion, this study indicates that both prototypical and specific representations play a role in prospection. Although location-familiarity did not moderate how liars and truth tellers describe their mental images of the future, this study allows some interesting insights into human future thinking. How these findings can be helpful for distinguishing between true and false intentions will be discussed.

  15. Been there before? Examining “familiarity” as a moderator for discriminating between true and false intentions

    PubMed Central

    Knieps, Melanie; Granhag, Pär A.; Vrij, Aldert

    2014-01-01

    Prospection is thinking about possible future states of the world. Commitment to perform a future action—commonly referred to as intention—is a specific type of prospection. This knowledge is relevant when trying to assess whether a stated intention is a lie or the truth. An important observation is that thinking of, and committing to, future actions often evoke vivid and detailed mental images. One factor that affects how specific a person experiences these simulations is location-familiarity. The purpose of this study was to examine to what extent location-familiarity moderates how liars and truth tellers describe a mental image in an investigative interview. Liars were instructed to plan a criminal act and truth tellers were instructed to plan a non-criminal act. Before they could carry out these acts, the participants were intercepted and interviewed about the mental images they may have had experienced in this planning phase. Truth tellers told the truth whereas liars used a cover story to mask their criminal intentions. As predicted, the results showed that the truth tellers reported a mental image significantly more often than the liars. If a mental image was reported, the content of the descriptions did not differ between liars and truth tellers. In a post interview questionnaire, the participants rated the vividness (i.e., content and clarity) of their mental images. The ratings revealed that the truth tellers had experienced their mental images more vividly during the planning phase than the liars. In conclusion, this study indicates that both prototypical and specific representations play a role in prospection. Although location-familiarity did not moderate how liars and truth tellers describe their mental images of the future, this study allows some interesting insights into human future thinking. How these findings can be helpful for distinguishing between true and false intentions will be discussed. PMID:25071648

  16. The Source of Adult Age Differences in Event-Based Prospective Memory: A Multinomial Modeling Approach

    ERIC Educational Resources Information Center

    Smith, Rebekah E.; Bayen, Ute J.

    2006-01-01

    Event-based prospective memory involves remembering to perform an action in response to a particular future event. Normal younger and older adults performed event-based prospective memory tasks in 2 experiments. The authors applied a formal multinomial processing tree model of prospective memory (Smith & Bayen, 2004) to disentangle age differences…

  17. Virtual reality-based prospective memory training program for people with acquired brain injury.

    PubMed

    Yip, Ben C B; Man, David W K

    2013-01-01

    Acquired brain injuries (ABI) may display cognitive impairments and lead to long-term disabilities including prospective memory (PM) failure. Prospective memory serves to remember to execute an intended action in the future. PM problems would be a challenge to an ABI patient's successful community reintegration. While retrospective memory (RM) has been extensively studied, treatment programs for prospective memory are rarely reported. The development of a treatment program for PM, which is considered timely, can be cost-effective and appropriate to the patient's environment. A 12-session virtual reality (VR)-based cognitive rehabilitation program was developed using everyday PM activities as training content. 37 subjects were recruited to participate in a pretest-posttest control experimental study to evaluate its treatment effectiveness. Results suggest that significantly better changes were seen in both VR-based and real-life PM outcome measures, related cognitive attributes such as frontal lobe functions and semantic fluency. VR-based training may be well accepted by ABI patients as encouraging improvement has been shown. Large-scale studies of a virtual reality-based prospective memory (VRPM) training program are indicated.

  18. Rumination mediates the prospective effect of low self-esteem on depression: a five-wave longitudinal study.

    PubMed

    Kuster, Farah; Orth, Ulrich; Meier, Laurenz L

    2012-06-01

    Previous research supports the vulnerability model of low self-esteem and depression, which states that low self-esteem operates as a prospective risk factor for depression. However, it is unclear which processes mediate the effect of low self-esteem. To test for the mediating effect of rumination, the authors used longitudinal mediation models, which included exclusively prospective effects and controlled for autoregressive effects of the constructs. Data came from 663 individuals (aged 16 to 62 years), who were assessed 5 times over an 8-month period. The results indicated that low self-esteem predicted subsequent rumination, which in turn predicted subsequent depression, and that rumination partially mediated the prospective effect of low self-esteem on depression. These findings held for both men and women, and for both affective-cognitive and somatic symptoms of depression. Future studies should test for the mediating effects of additional intrapersonal and interpersonal processes.

  19. Amnesia and future thinking: Exploring the role of memory in the quantity and quality of episodic future thoughts.

    PubMed

    Cole, Scott N; Morrison, Catriona M; Barak, Ohr; Pauly-Takacs, Katalin; Conway, Martin A

    2016-06-01

    To examine the impact of memory accessibility on episodic future thinking. Single-case study of neurological patient HCM and an age-matched comparison group of neurologically Healthy Controls. We administered a full battery of tests assessing general intelligence, memory, and executive functioning. To assess autobiographical memory, the Autobiographical Memory Interview (Kopelman, Wilson, & Baddeley, 1990. The Autobiographical Memory Interview. Bury St. Edmunds, UK: Thames Valley Test Company) was administered. The Past Episodic and Future Episodic sections of Dalla Barba's Confabulation Battery (Dalla Barba, 1993, Cogn. Neuropsychol., 1, 1) and a specifically tailored Mental Time Travel Questionnaire were administered to assess future thinking in HCM and age-matched controls. HCM presented with a deficit in forming new memories (anterograde amnesia) and recalling events from before the onset of neurological impairment (retrograde amnesia). HCM's autobiographical memory impairments are characterized by a paucity of memories from Recent Life. In comparison with controls, two features of his future thoughts are apparent: Reduced episodic future thinking and outdated content of his episodic future thoughts. This article suggests neuropsychologists should look beyond popular conceptualizations of the past-future relation in amnesia via focussing on reduced future thinking. Investigating both the quantity and quality of future thoughts produced by amnesic patients may lead to developments in understanding the complex nature of future thinking disorders resulting from memory impairments. We highlight the clinical importance of examining the content of future thoughts in amnesic patients, rather than only its quantitative reduction. We propose an explanation of how quantitative and qualitative aspects of future thinking could be affected by amnesia. This could provide a useful approach to understand clinical cases of impaired prospection. Systematic group investigations are required to fully examine our hypothesis. Although the current study utilized typical future thinking measures, these may be limited and we highlight the need to develop clinically relevant measures of prospection. © 2015 The British Psychological Society.

  20. Parenting styles and body mass index: a systematic review of prospective studies among children.

    PubMed

    Sokol, R L; Qin, B; Poti, J M

    2017-03-01

    Parenting style may be an important determinant of an individual's future weight status. However, reviews that evaluate the relationship between parenting style and weight-related outcomes have not focused on prospective studies. We systematically searched PubMed, Embase and PsychInfo for studies published between 1995 and 2016 that evaluated the prospective relationship between parenting style experienced in childhood and subsequent weight outcomes. We identified 11 prospective cohort studies. Among the eight studies that categorized parenting style into distinct groups (i.e. authoritative, authoritarian, permissive and neglectful), five provided evidence that authoritative parenting was associated with lower body mass index gains. Among the six highest quality studies, four suggested a protective role of authoritative parenting style against adverse weight-related outcomes. However, only one study controlled for a comprehensive set of confounders, and the small number of studies conducted within certain age groups precluded our ability to ascertain critical periods when parenting style is most strongly related to child weight. The present literature supports the idea that authoritative parenting may be protective against later overweight and obesity, although findings are mixed. More prospective cohort studies of longer durations, with more sophisticated methods that examine age-varying relationships, and that control for a comprehensive set of confounders, are needed. © 2017 World Obesity Federation.

  1. Parenting styles and body mass index: A systematic review of prospective studies among children

    PubMed Central

    Sokol, Rebeccah L; Qin, Bo; Poti, Jennifer M

    2017-01-01

    Background Parenting style may be an important determinant of an individual's future weight status. However, reviews that evaluate the relationship between parenting style and weight-related outcomes have not focused on prospective studies. Methods We systematically searched PubMed, Embase, and PsychInfo for studies published between 1995-2016 that evaluated the prospective relationship between parenting style experienced in childhood and subsequent weight outcomes. Results We identified eleven prospective cohort studies. Among the eight studies that categorized parenting style into distinct groups (i.e. authoritative, authoritarian, permissive, and neglectful), five provided evidence that authoritative parenting was associated with lower body mass index gains. Among the six highest quality studies, four suggested a protective role of authoritative parenting style against adverse weight-related outcomes. However, only one study controlled for a comprehensive set of confounders, and the small number of studies conducted within certain age groups precluded our ability to ascertain critical periods when parenting style is most strongly related to child weight. Conclusions The present literature supports the idea that authoritative parenting may be protective against later overweight and obesity, although findings are mixed. More prospective cohort studies of longer durations, with more sophisticated methods that examine age-varying relationships, and that control for a comprehensive set of confounders, are needed. PMID:28086262

  2. Neural Substrates of Semantic Prospection – Evidence from the Dementias

    PubMed Central

    Irish, Muireann; Eyre, Nadine; Dermody, Nadene; O’Callaghan, Claire; Hodges, John R.; Hornberger, Michael; Piguet, Olivier

    2016-01-01

    The ability to envisage personally relevant events at a future time point represents an incredibly sophisticated cognitive endeavor and one that appears to be intimately linked to episodic memory integrity. Far less is known regarding the neurocognitive mechanisms underpinning the capacity to envisage non-personal future occurrences, known as semantic future thinking. Moreover the degree of overlap between the neural substrates supporting episodic and semantic forms of prospection remains unclear. To this end, we sought to investigate the capacity for episodic and semantic future thinking in Alzheimer’s disease (n = 15) and disease-matched behavioral-variant frontotemporal dementia (n = 15), neurodegenerative disorders characterized by significant medial temporal lobe (MTL) and frontal pathology. Participants completed an assessment of past and future thinking across personal (episodic) and non-personal (semantic) domains, as part of a larger neuropsychological battery investigating episodic and semantic processing, and their performance was contrasted with 20 age- and education-matched healthy older Controls. Participants underwent whole-brain T1-weighted structural imaging and voxel-based morphometry analysis was conducted to determine the relationship between gray matter integrity and episodic and semantic future thinking. Relative to Controls, both patient groups displayed marked future thinking impairments, extending across episodic and semantic domains. Analyses of covariance revealed that while episodic future thinking deficits could be explained solely in terms of episodic memory proficiency, semantic prospection deficits reflected the interplay between episodic and semantic processing. Distinct neural correlates emerged for each form of future simulation with differential involvement of prefrontal, lateral temporal, and medial temporal regions. Notably, the hippocampus was implicated irrespective of future thinking domain, with the suggestion of lateralization effects depending on the type of information being simulated. Whereas episodic future thinking related to right hippocampal integrity, semantic future thinking was found to relate to left hippocampal integrity. Our findings support previous observations of significant MTL involvement for semantic forms of prospection and point to distinct neurocognitive mechanisms which must be functional to support future-oriented forms of thought across personal and non-personal contexts. PMID:27252632

  3. Trends In High School Seniors' Views of the Military. Monitoring the Future Occasional Paper 12.

    ERIC Educational Resources Information Center

    Bachman, Jerald G.

    The paper provides an overview of high school seniors' views of the military as an institution, and also as a prospective work role. Data were obtained from the Monitoring the Future project, an ongoing study of high school seniors conducted by the Institute for Social Research. Surveys were mailed to a national sampling of high school senior…

  4. [Current recommendations for basic/advanced life support : Addressing unanswered questions and future prospects].

    PubMed

    Fink, K; Schmid, B; Busch, H-J

    2016-11-01

    The revised guidelines for cardiopulmonary resuscitation were implemented by the European Resuscitation Council (ERC) in October 2015. There were few changes concerning basic and advanced life support; however, some issues were clarified compared to the ERC recommendations from 2010. The present paper summarizes the procedures of basic and advanced life support according to the current guidelines and highlights the updates of 2015. Furthermore, the article depicts future prospects of cardiopulmonary resuscitation that may improve outcome of patients after cardiac arrest in the future.

  5. Development and Implementation of Science and Technology Ethics Education Program for Prospective Science Teachers

    NASA Astrophysics Data System (ADS)

    Rhee, Hyang-yon; Choi, Kyunghee

    2014-05-01

    The purposes of this study were (1) to develop a science and technology (ST) ethics education program for prospective science teachers, (2) to examine the effect of the program on the perceptions of the participants, in terms of their ethics and education concerns, and (3) to evaluate the impact of the program design. The program utilized problem-based learning (PBL) which was performed as an iterative process during two cycles. A total of 23 and 29 prospective teachers in each cycle performed team activities. A PBL-based ST ethics education program for the science classroom setting was effective in enhancing participants' perceptions of ethics and education in ST. These perceptions motivated prospective science teachers to develop and implement ST ethics education in their future classrooms. The change in the prospective teachers' perceptions of ethical issues and the need for ethics education was greater when the topic was controversial.

  6. Prognostic factors for work ability in women with chronic low back pain consulting primary health care: a 2-year prospective longitudinal cohort study.

    PubMed

    Nordeman, Lena; Gunnarsson, Ronny; Mannerkorpi, Kaisa

    2014-05-01

    To investigate prognostic factors for future work ability in women with chronic low back pain (CLBP) consulting primary health care. A 2-year prospective longitudinal cohort study of female patients with CLBP within the primary health care was conducted. Patients were assessed at the first assessment and after 2 years. Prognostic factors for work ability (yes/no) were analyzed by multivariate regression. A total of 130 patients were included at first assessment. After 2 years, 123 patients (95%) were followed up. The 6-minute walk test, depression, and earlier work ability predicted work ability at the 2-year follow-up. A nomogram was constructed to assess the probability of future work ability. The 6-minute walk test, work ability, and depression predicted work ability for women with CLBP after 2 years.

  7. Psychological Predictors of Mortality: Evidence from a 41-Year Prospective Study.

    ERIC Educational Resources Information Center

    Graves, Pirkko L.; And Others

    The Precursors Study, initiated in 1946, has focused on searching for links between psychological patterns and future disease and death. Gathering a broad spectrum of psychobiological characteristics from a large group of medical students, this study has continued year after year. This study examined the role of psychological factors on mortality,…

  8. Nonsuicidal self-injury in community adolescents: A systematic review of prospective predictors, mediators and moderators.

    PubMed

    Valencia-Agudo, Fatima; Burcher, Georgina Corbet; Ezpeleta, Lourdes; Kramer, Tami

    2018-06-01

    Nonsuicidal self-injury (NSSI) usually starts during adolescence and is associated with an array of psychological and psychiatric symptoms and future suicide attempts. The aim of this study is to determine prospective predictors, mediators and moderators of NSSI in adolescent community samples in order to target prevention and treatment strategies. Two team members searched online databases independently. Thirty-nine studies were included in the review. Several variables were seen to prospectively predict NSSI: female gender, family-related variables, peer victimisation, depression, previous NSSI and self-concept. Few studies analysed mediators and moderators. Low self-concept was highlighted as a relevant moderator in the relationship between intra/interpersonal variables and NSSI. Implications of these findings are discussed. The considerable heterogeneity between studies posed a limitation to determine robust predictors of NSSI. Further prospective studies using standardised measures of predictors and outcomes are needed to ascertain the most at risk individuals and develop prevention strategies. Copyright © 2018 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

  9. Real-time web-based assessment of total population risk of future emergency department utilization: statewide prospective active case finding study.

    PubMed

    Hu, Zhongkai; Jin, Bo; Shin, Andrew Y; Zhu, Chunqing; Zhao, Yifan; Hao, Shiying; Zheng, Le; Fu, Changlin; Wen, Qiaojun; Ji, Jun; Li, Zhen; Wang, Yong; Zheng, Xiaolin; Dai, Dorothy; Culver, Devore S; Alfreds, Shaun T; Rogow, Todd; Stearns, Frank; Sylvester, Karl G; Widen, Eric; Ling, Xuefeng B

    2015-01-13

    An easily accessible real-time Web-based utility to assess patient risks of future emergency department (ED) visits can help the health care provider guide the allocation of resources to better manage higher-risk patient populations and thereby reduce unnecessary use of EDs. Our main objective was to develop a Health Information Exchange-based, next 6-month ED risk surveillance system in the state of Maine. Data on electronic medical record (EMR) encounters integrated by HealthInfoNet (HIN), Maine's Health Information Exchange, were used to develop the Web-based surveillance system for a population ED future 6-month risk prediction. To model, a retrospective cohort of 829,641 patients with comprehensive clinical histories from January 1 to December 31, 2012 was used for training and then tested with a prospective cohort of 875,979 patients from July 1, 2012, to June 30, 2013. The multivariate statistical analysis identified 101 variables predictive of future defined 6-month risk of ED visit: 4 age groups, history of 8 different encounter types, history of 17 primary and 8 secondary diagnoses, 8 specific chronic diseases, 28 laboratory test results, history of 3 radiographic tests, and history of 25 outpatient prescription medications. The c-statistics for the retrospective and prospective cohorts were 0.739 and 0.732 respectively. Integration of our method into the HIN secure statewide data system in real time prospectively validated its performance. Cluster analysis in both the retrospective and prospective analyses revealed discrete subpopulations of high-risk patients, grouped around multiple "anchoring" demographics and chronic conditions. With the Web-based population risk-monitoring enterprise dashboards, the effectiveness of the active case finding algorithm has been validated by clinicians and caregivers in Maine. The active case finding model and associated real-time Web-based app were designed to track the evolving nature of total population risk, in a longitudinal manner, for ED visits across all payers, all diseases, and all age groups. Therefore, providers can implement targeted care management strategies to the patient subgroups with similar patterns of clinical histories, driving the delivery of more efficient and effective health care interventions. To the best of our knowledge, this prospectively validated EMR-based, Web-based tool is the first one to allow real-time total population risk assessment for statewide ED visits.

  10. System and prospects of China's intercity rail transit technology

    NASA Astrophysics Data System (ADS)

    Gong, Ming

    2018-06-01

    City clusters and metropolitan areas in China are flourishing in the midst of the deepening urbanization in the country, thereby resulting in the emergence of intercity rail transit. Intercity railways connect mainline and urban railways for an integrated regional transportation system that underpins and leads the development of city clusters and metropolitan areas. This study explores the development mode and service characteristics of intercity rail transit, as well as proposes overviews on this system and prospects of its future technology in China.

  11. Prospective Memory Impairments in Alzheimer's Disease and Behavioral Variant Frontotemporal Dementia: Clinical and Neural Correlates.

    PubMed

    Dermody, Nadene; Hornberger, Michael; Piguet, Olivier; Hodges, John R; Irish, Muireann

    2016-01-01

    Prospective memory (PM) refers to a future-oriented form of memory in which the individual must remember to execute an intended action either at a future point in time (Time-based) or in response to a specific event (Event-based). Lapses in PM are commonly exhibited in neurodegenerative disorders including Alzheimer's disease (AD) and frontotemporal dementia (FTD), however, the neurocognitive mechanisms driving these deficits remain unknown. To investigate the clinical and neural correlates of Time- and Event-based PM disruption in AD and the behavioral-variant FTD (bvFTD). Twelve AD, 12 bvFTD, and 12 healthy older Control participants completed a modified version of the Cambridge Prospective Memory test, which examines Time- and Event-based aspects of PM. All participants completed a standard neuropsychological assessment and underwent whole-brain structural MRI. AD and bvFTD patients displayed striking impairments across Time- and Event-based PM relative to Controls, however, Time-based PM was disproportionately affected in the AD group. Episodic memory dysfunction and hippocampal atrophy were found to correlate strongly with PM integrity in both patient groups, however, dissociable neural substrates were also evident for PM performance across dementia syndromes. Our study reveals the multifaceted nature of PM dysfunction in neurodegenerative disorders, and suggests common and dissociable neurocognitive mechanisms, which subtend these deficits in each patient group. Future studies of PM disturbance in dementia syndromes will be crucial for the development of successful interventions to improve functional independence in the patient's daily life.

  12. The future of dream science.

    PubMed

    Bulkeley, Kelly

    2017-10-01

    This article describes the future prospects of scientific dream research. Three frontiers of investigation hold special promise: neuroscientific studies of the brain-mind system's activities during sleep (such as during lucid dreaming); systematic analyses of large collections of dream reports from diverse populations of people; and psychotherapeutic explorations of the multiple dimensions of personal and collective meaning woven into the dream experiences of each individual. Several helpful books on the science of sleep and dreaming are mentioned for further study. © 2017 New York Academy of Sciences.

  13. Predictors of Dropout From Inpatient Substance Use Treatment: A Prospective Cohort Study.

    PubMed

    Andersson, Helle Wessel; Steinsbekk, Aslak; Walderhaug, Espen; Otterholt, Eli; Nordfjærn, Trond

    2018-01-01

    Dropout from inpatient treatment for substance use disorder (SUD) is an ongoing challenge. The aim of this study was to identify demographic, substance use, and psychological factors that predict dropout from postdetoxification inpatient SUD treatment. A total of 454 patients from 5 inpatient SUD centers in Central Norway were consecutively included in this naturalistic, prospective cohort study. A total of 132 patients (28%) did not complete the planned treatment stay (dropped out). Cox regression analysis showed that higher levels of intrinsic motivation for changing personal substance use reduced the dropout risk (adjusted hazard ratio [adjHR]: 0.62, 95% confidence interval [CI]: 0.48-0.79). Higher levels of mental distress were associated with an increased risk for dropout (adjHR: 1.48, 95% CI: 1.11-1.97). The role of mental health and motivation in reducing dropout risk from inpatient SUD treatment should be targeted in future prospective intervention studies.

  14. A Review on Current Status and Future Prospects of Winged Bean (Psophocarpus tetragonolobus) in Tropical Agriculture.

    PubMed

    Lepcha, Patrush; Egan, Ashley N; Doyle, Jeff J; Sathyanarayana, N

    2017-09-01

    Winged bean, Psophocarpus tetragonolobus (L.) DC., is analogous to soybean in yield and nutritional quality, proving a valuable alternative to soybean in tropical regions of the world. The presence of anti-nutritional factors and high costs associated with indeterminate plant habit have been major concerns in this crop. But occurrence of good genetic variability in germplasm collections offers precious resources for winged bean breeding. However, lack of germplasm characterization is hindering such efforts. From a genomic standpoint, winged bean has been little studied despite rapid advancement in legume genomics in the last decade. Exploiting modern genomics/breeding approaches for genetic resource characterization and the breeding of early maturing, high yielding, determinate varieties which are disease resistant and free of anti-nutritional factors along with developing consumer friendly value-added products of local significance are great challenges and opportunities in the future that would boost cultivation of winged bean in the tropics. We review past efforts and future prospects towards winged bean improvement.

  15. Prospective memory functioning: a new area of investigation in the clinical neuropsychology and rehabilitation of Parkinson's disease and mild cognitive impairment. Review of evidence.

    PubMed

    Costa, Alberto; Carlesimo, Giovanni Augusto; Caltagirone, Carlo

    2012-10-01

    The integrity of prospective memory (PM) is likely crucial for independent human behavior. PM refers to the ability to execute an intention after a certain delay. Its impaired functioning may significantly affect the correct execution of common daily activities, such as taking a pill at a certain time or complying with future plans. The results of recent studies indicate that PM is impaired pervasively and early in individuals with mild cognitive impairment (MCI) and Parkinson's disease (PD). In this study, we reviewed studies investigating the characteristics of PM disorders in these individuals and the potential for cognitive rehabilitation. The PM profiles of individuals with MCI and PD indicate that interventions aimed at enhancing the different cognitive processes underlying their PM disorders could be useful. At the current state of the art, however, no evidence-based protocols are available. Therefore, the discussion proposed here should be considered an attempt to identify some valuable perspectives for future research and interventions.

  16. The Carvedilol Prospective Randomized Cumulative Survival (COPERNICUS) trial.

    PubMed

    Eichhorn, Eric J; Bristow, Michael R

    2001-01-01

    Previous trials (Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure [MERIT-HF], Cardiac Insufficiency Bisoprolol Study [CIBIS] II) have demonstrated a mortality benefit of beta-adrenergic blockade in patients with mild to moderate heart failure. The recent Carvedilol Prospective Randomized Cumulative Survival (COPERNICUS) trial has extended these results to a more advanced patient population. This trial did not, however, include patients who could not reach compensation, patients with far advanced heart failure symptoms, or a significant number of black patients. Future studies of beta-blockade may focus on these patients or patients with asymptomatic left ventricular dysfunction.

  17. The Carvedilol Prospective Randomized Cumulative Survival (COPERNICUS) trial

    PubMed Central

    Eichhorn, Eric J; Bristow, Michael R

    2001-01-01

    Previous trials (Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure [MERIT-HF], Cardiac Insufficiency Bisoprolol Study [CIBIS] II) have demonstrated a mortality benefit of β-adrenergic blockade in patients with mild to moderate heart failure. The recent Carvedilol Prospective Randomized Cumulative Survival (COPERNICUS) trial has extended these results to a more advanced patient population. This trial did not, however, include patients who could not reach compensation, patients with far advanced heart failure symptoms, or a significant number of black patients. Future studies of β-blockade may focus on these patients or patients with asymptomatic left ventricular dysfunction. PMID:11806769

  18. Introduction: Deep-Sea Hot Springs and Cold Seeps.

    ERIC Educational Resources Information Center

    Gross, M. Grant

    1984-01-01

    Describes: (1) various research studies of the mid-ocean ridges; (2) how money and facilities are made available for these studies; and (3) the prospect for future ocean floor studies. Indicates that a presidential proclamation (Exclusive Economic Zone) has extended United States boundaries 200 nautical miles seaward, adding new exploration sites.…

  19. Changing Housing Patterns in Metropolitan Washington

    ERIC Educational Resources Information Center

    Grier, George; Grier, Eunice

    1975-01-01

    This testimony, before a public hearing of the New York City Commission on Human Rights in May 1974, summarizes extensive studies of changing minority residential patterns in metropolitan Washington and less extensive studies of other groups; the prospects for future desegregation and for using the growing economic potential of minority families…

  20. A Characterization of Individual Differences in Prospective Memory Monitoring Using the Complex Ongoing Serial Task

    ERIC Educational Resources Information Center

    Savine, Adam C.; McDaniel, Mark A.; Shelton, Jill Talley; Scullin, Michael K.

    2012-01-01

    Prospective memory--remembering to retrieve and execute future goals--is essential to daily life. Prospective remembering is often achieved through effortful monitoring; however, potential individual differences in monitoring patterns have not been characterized. We propose 3 candidate models to characterize the individual differences present in…

  1. Attitudes of Prospective High School Mathematics Teachers towards Integrating Information Technologies into Their Future Teaching.

    ERIC Educational Resources Information Center

    Hazzan, Orit

    This paper examines why the number of high school mathematics teachers who integrate computers into their math classes remains relatively low by analyzing the attitudes of prospective high school mathematics teachers. Data were gathered from written questionnaires and class discussions of four classes of prospective high school mathematics…

  2. Financing the Public Schools in the Great Lake States: Declining Revenues in the 1980s?

    ERIC Educational Resources Information Center

    Geske, Terry G.

    1984-01-01

    Analyzes data on the economic prospects of Illinois, Indiana, Michigan, Ohio, and Wisconsin--including demographic and economic trends, trends in taxation systems, school revenue and expenditure trends, and future revenue prospects--and offers prognoses for individual states. Generally, short-range revenue prospects are bleak, and long-range…

  3. Psychosocial Working Conditions and Cognitive Complaints among Swedish Employees

    PubMed Central

    Stenfors, Cecilia U. D.; Magnusson Hanson, Linda; Oxenstierna, Gabriel; Theorell, Töres; Nilsson, Lars-Göran

    2013-01-01

    Background Cognitive complaints involving problems with concentration, memory, decision-making and thinking are relatively common in the work force. The sensitivity of both subjective and objective cognitive functioning to common psychiatric conditions, stress levels and to cognitive load makes it plausible that psychosocial working conditions play a role in cognitive complaints. Thus, this study aimed to test the associations between psychosocial work factors and cognitive complaints in nationally representative samples of the Swedish work force. Cross-sectional (n = 9751) and prospective (n = 3644; two time points two years apart) sequential multiple regression analyses were run, adjusting for general confounders, depressive- and sleeping problems. Additional prospective analyses were run adjusting for baseline cognitive complaints. Cross-sectional results High quantitative demands, information and communication technology (ICT) demands, underqualification and conflicts were positively associated with cognitive complaints, while social support, good resources at work and overqualification were negatively associated with cognitive complaints in all models. Skill discretion and decision authority were weakly associated with cognitive complaints. Conflicts were more strongly associated with cognitive complaints in women than in men, after adjustment for general confounders. Prospective results Quantitative job demands, ICT demands and underqualification were positively associated with future cognitive complaints in all models, including when adjusted for baseline cognitive complaints. Decision authority was weakly positively associated with future cognitive complaints, only after adjustment for depressive- and sleeping problems respectively. Social support was negatively associated with future cognitive complaints after adjustment for general confounders and baseline cognitive complaints. Skill discretion and resources were negatively associated with future cognitive complaints after adjustment for general confounders. The associations between quantitative demands and future cognitive complaints were stronger in women. Discussion/Conclusions The findings indicate that psychosocial working conditions should be taken into account when considering cognitive complaints among employees. PMID:23560101

  4. Polysaccharides in Lentinus edodes: isolation, structure, immunomodulating activity and future prospective.

    PubMed

    Xu, Xiaofei; Yan, Huidan; Tang, Jian; Chen, Jian; Zhang, Xuewu

    2014-01-01

    Lentinus edodes has been valued as edible and medical resources. Polysaccharides have been known to be the most potent antitumor and immunomodulating substance in Lentinus edodes. In this review, we summarize the current knowledge of the polysaccharides isolated from Lentinus edodes, including extraction and purification methods, chemical structure and chain conformation, the effects on innate and adaptive immunity and their mechanism, relationship between structure and function, and the future prospects.

  5. 49 CFR 1018.62 - Reasons for terminating collection action.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... debtor's future financial prospects, and the exemptions available to the debtor under State and Federal... applicable statute of limitations has run, and the prospects of collecting by offset, notwithstanding the bar...

  6. 42 CFR 401.621 - Termination of collection action.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... available; (ii) The debtor's future financial prospects; and (iii) Exemptions available to the debtor under... statute of limitations has run; or (iii) The prospects of collecting by offset, whether or not an...

  7. An Historical Summary and Prospects for the Future of Spacecraft Batteries

    NASA Technical Reports Server (NTRS)

    Halpert, Gerald; Surampudi, S.

    1998-01-01

    Subjects covered in this report include a historical evolution of batteries in space, evolution and status of nickel-cadmium batteries and nickel-hydrogen batteries, present applications, future applications and advanced batteries for future missions.

  8. Large-scale educational telecommunications systems for the US: An analysis of educational needs and technological opportunities

    NASA Technical Reports Server (NTRS)

    Morgan, R. P.; Singh, J. P.; Rothenberg, D.; Robinson, B. E.

    1975-01-01

    The needs to be served, the subsectors in which the system might be used, the technology employed, and the prospects for future utilization of an educational telecommunications delivery system are described and analyzed. Educational subsectors are analyzed with emphasis on the current status and trends within each subsector. Issues which affect future development, and prospects for future use of media, technology, and large-scale electronic delivery within each subsector are included. Information on technology utilization is presented. Educational telecommunications services are identified and grouped into categories: public television and radio, instructional television, computer aided instruction, computer resource sharing, and information resource sharing. Technology based services, their current utilization, and factors which affect future development are stressed. The role of communications satellites in providing these services is discussed. Efforts to analyze and estimate future utilization of large-scale educational telecommunications are summarized. Factors which affect future utilization are identified. Conclusions are presented.

  9. Reflective action assessment with a prospective clinical problem solving tool in the context of rehabilitation medicine: an illustrative case study.

    PubMed

    Kellett, David; Mpofu, Elias; Madden, Richard

    2013-06-01

    This study describes a case formulation approach applying a prospective ICF derived clinical tool to assess rehabilitation needs for a community dwelling stroke survivor with care from an outpatient rehabilitation medicine clinic. Case history data on the person were assessed for rehabilitation management planning using a prospective tool to interlink current with projected future functional status in everyday settings. Implicit assessment with reflective action informed decision points at each stage of the rehabilitation process. As a result of reflective action using the prospective tool, rehabilitation management led to significant changes in client participation after limitations to mobility and self care were mapped to the living conditions of the stroke survivor. The context sensitive rehabilitative plan resulted in higher subjective health-related quality of life in the stroke survivor and significant other and enhanced their capacity for participation. Reflective action informed assessment applying ICF concepts to clinical problem solving resulted in positive gains in health-related quality of life in a stroke survivor.

  10. Motivation, study habits, and expectations of medical students in Singapore.

    PubMed

    Amin, Zubair; Tani, Massimiliano; Eng, Khoo Hoon; Samarasekara, Dujeepa D; Huak, Chan Yiong

    2009-12-01

    To determine the motivation and incentives in education, learning experience and teaching techniques, and expectations about future careers among medical students from a multi-ethnic Asian country. Pre-validated questionnaire-based survey with stratified random sampling among medical students. The questionnaire combined qualitative responses with semi-quantitative measures of available alternatives. The response rate was 83.1%. The most important factor for pursuing university study was 'prospect of finding an interesting challenging job' (rank 1-75%). Family made a significant contribution in decision making. Given the chance, a majority (67.2%) of respondents would prefer to study overseas. The main deterring factors were cost (67.7%), distance from home (28%), and local opportunity for post-graduation (23.4%). Despite their inclination of study overseas, the majority (73.9%) of the respondents indicated they were either very satisfied or satisfied with their current choice of university study. Only 20% of students were comfortable in asking questions in classroom as asking questions was deemed 'too risky' and 'unnecessary to get better grades'. Students adopted strategies related to assessment and competition to monitor their study. Senior students reported university education as less relevant to their future careers as compared to junior students (p = 0.002). Students' learning behaviour is determined by complex factors such as educational incentives, learning support, assessment and competition. Among several external factors, family, job prospects and expectations about the future play a critical role in education.

  11. Organisational justice and mental health: a systematic review of prospective studies.

    PubMed

    Ndjaboué, Ruth; Brisson, Chantal; Vézina, Michel

    2012-10-01

    The models most commonly used, to study the effects of psychosocial work factors on workers' health, are the demand-control-support (DCS) model and Effort-Reward Imbalance (ERI) model. An emerging body of research has identified Organisational Justice as another model that can help to explain deleterious health effects. This review aimed: (1) to identify prospective studies of the associations between organisational justice and mental health in industrialised countries from 1990 to 2010; (2) to evaluate the extent to which organisational justice has an effect on mental health independently of the DCS and ERI models; and (3) to discuss theoretical and empirical overlap and differences with previous models. The studies had to present associations between organisational justice and a mental health outcome, be prospective, and be entirely available in English or in French. Duplicated papers were excluded. Eleven prospective studies were selected for this review. They provide evidence that procedural justice and relational justice are associated with mental health. These associations remained significant even after controlling for the DCS and ERI models. There is a lack of prospective studies on distributive and informational justice. In conclusion, procedural and relational justice can be considered a different and complementary model to the DCS and ERI models. Future studies should evaluate the effect of change in exposure to organisational justice on employees' mental health over time.

  12. Deliberative democracy in health care: current challenges and future prospects.

    PubMed

    Safaei, Jalil

    2015-01-01

    There is a vast body of literature on deliberative, participative, or engaged democracy. In the area of health care there is a rapidly expanding literature on deliberative democracy as embodied in various notions of public engagement, shared decision-making (SDM), patient-centered care, and patient/care provider autonomy over the past few decades. It is useful to review such literature to get a sense of the challenges and prospects of introducing deliberative democracy in health care. This paper reviews the key literature on deliberative democracy and SDM in health care settings with a focus on identifying the main challenges of promoting this approach in health care, and recognizing its progress so far for mapping out its future prospects in the context of advanced countries. Several databases were searched to identify the literature pertinent to the subject of this study. A total of 56 key studies in English were identified and reviewed carefully for indications and evidence of challenges and/or promising avenues of promoting deliberative democracy in health care. Time pressure, lack of financial motivation, entrenched professional interests, informational imbalance, practical feasibility, cost, diversity of decisions, and contextual factors are noted as the main challenges. As for the prospects, greater clarity on conception of public engagement and policy objectives, real commitment of the authorities to public input, documenting evidence of the effectiveness of public involvement, development of patient decision supports, training of health professionals in SDM, and use of multiple and flexible methods of engagement leadership suited to specific contexts are the main findings in the reviewed literature. Seeking deliberative democracy in health care is both challenging and rewarding. The challenges have been more or less identified. However, its prospects are potentially significant. Such prospects are more likely to materialize if deliberative democracy is pursued more systematically in the broader sociopolitical domains.

  13. Deliberative democracy in health care: current challenges and future prospects

    PubMed Central

    Safaei, Jalil

    2015-01-01

    Background There is a vast body of literature on deliberative, participative, or engaged democracy. In the area of health care there is a rapidly expanding literature on deliberative democracy as embodied in various notions of public engagement, shared decision-making (SDM), patient-centered care, and patient/care provider autonomy over the past few decades. It is useful to review such literature to get a sense of the challenges and prospects of introducing deliberative democracy in health care. Objective This paper reviews the key literature on deliberative democracy and SDM in health care settings with a focus on identifying the main challenges of promoting this approach in health care, and recognizing its progress so far for mapping out its future prospects in the context of advanced countries. Method Several databases were searched to identify the literature pertinent to the subject of this study. A total of 56 key studies in English were identified and reviewed carefully for indications and evidence of challenges and/or promising avenues of promoting deliberative democracy in health care. Results Time pressure, lack of financial motivation, entrenched professional interests, informational imbalance, practical feasibility, cost, diversity of decisions, and contextual factors are noted as the main challenges. As for the prospects, greater clarity on conception of public engagement and policy objectives, real commitment of the authorities to public input, documenting evidence of the effectiveness of public involvement, development of patient decision supports, training of health professionals in SDM, and use of multiple and flexible methods of engagement leadership suited to specific contexts are the main findings in the reviewed literature. Conclusion Seeking deliberative democracy in health care is both challenging and rewarding. The challenges have been more or less identified. However, its prospects are potentially significant. Such prospects are more likely to materialize if deliberative democracy is pursued more systematically in the broader sociopolitical domains. PMID:29355181

  14. On the Representational Systems Underlying Prospection: Evidence from the Event-Cueing Paradigm

    ERIC Educational Resources Information Center

    D'Argembeau, Arnaud; Demblon, Julie

    2012-01-01

    The ability to think about the future--prospection--is central to many aspects of human cognition and behavior, from planning and decision making, to self-control and the construction of a sense of identity. Yet, the exact nature of the representational systems underlying prospection is not fully understood. Recent findings point to the critical…

  15. Internalizing versus Externalizing Control: Different Ways to Perform a Time-Based Prospective Memory Task

    ERIC Educational Resources Information Center

    Huang, Tracy; Loft, Shayne; Humphreys, Michael S.

    2014-01-01

    "Time-based prospective memory" (PM) refers to performing intended actions at a future time. Participants with time-based PM tasks can be slower to perform ongoing tasks (costs) than participants without PM tasks because internal control is required to maintain the PM intention or to make prospective-timing estimates. However, external…

  16. A Prospective Test of Cognitive Vulnerability Models of Depression With Adolescent Girls

    PubMed Central

    Bohon, Cara; Stice, Eric; Burton, Emily; Fudell, Molly; Nolen-Hoeksema, Susan

    2009-01-01

    This study sought to provide a more rigorous prospective test of two cognitive vulnerability models of depression with longitudinal data from 496 adolescent girls. Results supported the cognitive vulnerability model in that stressors predicted future increases in depressive symptoms and onset of clinically significant major depression for individuals with a negative attributional style, but not for those with a positive attributional style, although these effects were small. This model appeared to be specific to depression, in that it did not predict future increases in bulimia nervosa or substance abuse symptoms. In contrast, results did not support the integrated cognitive vulnerability self-esteem model that asserts stressors should only predict increased depression for individuals with a confluence of negative attributional style and low self-esteem, and this model did not appear to be specific to depression. PMID:18328873

  17. Sociology of Low Expectations: Recalibration as Innovation Work in Biomedicine.

    PubMed

    Gardner, John; Samuel, Gabrielle; Williams, Clare

    2015-11-01

    Social scientists have drawn attention to the role of hype and optimistic visions of the future in providing momentum to biomedical innovation projects by encouraging innovation alliances. In this article, we show how less optimistic, uncertain, and modest visions of the future can also provide innovation projects with momentum. Scholars have highlighted the need for clinicians to carefully manage the expectations of their prospective patients. Using the example of a pioneering clinical team providing deep brain stimulation to children and young people with movement disorders, we show how clinicians confront this requirement by drawing on their professional knowledge and clinical expertise to construct visions of the future with their prospective patients; visions which are personalized, modest, and tainted with uncertainty. We refer to this vision-constructing work as recalibration, and we argue that recalibration enables clinicians to manage the tension between the highly optimistic and hyped visions of the future that surround novel biomedical interventions, and the exigencies of delivering those interventions in a clinical setting. Drawing on work from science and technology studies, we suggest that recalibration enrolls patients in an innovation alliance by creating a shared understanding of how the "effectiveness" of an innovation shall be judged.

  18. Prospective thinking and decision making in primary school age children.

    PubMed

    Lombardi, Elisabetta; Di Dio, Cinzia; Castelli, Ilaria; Massaro, Davide; Marchetti, Antonella

    2017-06-01

    In this study, we seek to widen our understanding of the developmental processes underlying bargaining behaviour in children addressing the concept of prospective thinking. We argue that the emergence of the capacity to think prospectively about future outcomes or behaviours in response to current actions is a required precedent to strategic decision making. To test this idea, we compared 6, 8 and 10 years old children's performance on three tasks: the ultimatum game assessing fairness/inequality aversion, the marshmallow task, an intertemporal choice task evaluating the ability to delay gratification, and the dictator game assessing altruism. The children's socio-demographic and cognitive variables were also evaluated. We hypothesized that development of strategic thinking in the ultimatum game is related to an increased ability to delay gratification - given that both tasks require looking at prospective benefits - and, crucially, not to altruism, which benefits from immediate selfless reward. Our results confirmed our hypothesis suggesting that increased strategic planning with age would also stem from the development of competencies like prospective thinking.

  19. A prospective study of mandibular trabecular bone to predict fracture incidence in women: a low-cost screening tool in the dental clinic.

    PubMed

    Jonasson, Grethe; Sundh, Valter; Ahlqwist, Margareta; Hakeberg, Magnus; Björkelund, Cecilia; Lissner, Lauren

    2011-10-01

    Bone structure is the key to the understanding of fracture risk. The hypothesis tested in this prospective study is that dense mandibular trabeculation predicts low fracture risk, whereas sparse trabeculation is predictive of high fracture risk. Out of 731 women from the Prospective Population Study of Women in Gothenburg with dental examinations at baseline 1968, 222 had their first fracture in the follow-up period until 2006. Mandibular trabeculation was defined as dense, mixed dense plus sparse, and sparse based on panoramic radiographs from 1968 and/or 1980. Time to fracture was ascertained and used as the dependent variable in three Cox proportional hazards regression analyses. The first analysis covered 12 years of follow-up with self-reported endpoints; the second covered 26 years of follow-up with hospital verified endpoints; and the third combined the two follow-up periods, totaling 38 years. Mandibular trabeculation was the main independent variable predicting incident fractures, with age, physical activity, alcohol consumption and body mass index as covariates. The Kaplan-Meier curve indicated a graded association between trabecular density and fracture risk. During the whole period covered, the hazard ratio of future fracture for sparse trabeculation compared to mixed trabeculation was 2.9 (95% CI: 2.2-3.8, p<0.0001), and for dense versus mixed trabeculation was 0.21 (95% CI: 0.1-0.4, p<0.0001). The trabecular pattern was a highly significant predictor of future fracture risk. Our findings imply that dentists, using ordinary dental radiographs, can identify women at high risk for future fractures at 38-54 years of age, often long before the first fracture occurs. Copyright © 2011 Elsevier Inc. All rights reserved.

  20. Understandings of Current Environmental Issues: Turkish Case Study in Six Teacher Education Colleges

    ERIC Educational Resources Information Center

    Cakir, Mustafa; Irez, Serhat; Dogan, Ozgur Kivilcan

    2010-01-01

    The purpose of this study is to profile future science teachers' understandings of current environmental issues in the context of an education reform in Turkey. Knowledge base and understandings of elementary and secondary prospective science teachers about biodiversity, carbon cycle, global warming and ozone layer depletion were targeted in the…

  1. Career Repertoires of IT Students: A Group Counselling Case Study in Higher Education

    ERIC Educational Resources Information Center

    Penttinen, Leena; Vesisenaho, Mikko

    2013-01-01

    Uncertainty about future career prospects has increased enormously for students enrolled in higher education Information Technology (IT) programs. However, many computer science programmes pay little attention to career counselling. This article reports the results of a pilot study intended to develop group counselling for IT students to promote…

  2. Instant World; A Report on Telecommunications in Canada.

    ERIC Educational Resources Information Center

    Information Canada, Ottawa (Ontario).

    Telecommission, the study of the present state and future prospects of telecommunications in Canada, began in 1969. This general report focuses attention on the main issues and problems disclosed by the 40 individual Telecommission studies and presents options for consideration. Part one of the report sets out the complex background of problems…

  3. Research Leads: Current Practice, Future Prospects

    ERIC Educational Resources Information Center

    Riggall, Anna; Singer, Rachel

    2015-01-01

    This report was conceived as one of three publications that collectively provide a commentary on research awareness and research use within schools in England. This third report in the series presents findings from a small-scale, detailed study of teachers who are operating as their school's Research Lead. The small scale of the study is…

  4. Acute pancreatitis patient registry to examine novel therapies in clinical experience (APPRENTICE): an international, multicenter consortium for the study of acute pancreatitis.

    PubMed

    Papachristou, Georgios I; Machicado, Jorge D; Stevens, Tyler; Goenka, Mahesh Kumar; Ferreira, Miguel; Gutierrez, Silvia C; Singh, Vikesh K; Kamal, Ayesha; Gonzalez-Gonzalez, Jose A; Pelaez-Luna, Mario; Gulla, Aiste; Zarnescu, Narcis O; Triantafyllou, Konstantinos; Barbu, Sorin T; Easler, Jeffrey; Ocampo, Carlos; Capurso, Gabriele; Archibugi, Livia; Cote, Gregory A; Lambiase, Louis; Kochhar, Rakesh; Chua, Tiffany; Tiwari, Subhash Ch; Nawaz, Haq; Park, Walter G; de-Madaria, Enrique; Lee, Peter J; Wu, Bechien U; Greer, Phil J; Dugum, Mohannad; Koutroumpakis, Efstratios; Akshintala, Venkata; Gougol, Amir

    2017-01-01

    We have established a multicenter international consortium to better understand the natural history of acute pancreatitis (AP) worldwide and to develop a platform for future randomized clinical trials. The AP patient registry to examine novel therapies in clinical experience (APPRENTICE) was formed in July 2014. Detailed web-based questionnaires were then developed to prospectively capture information on demographics, etiology, pancreatitis history, comorbidities, risk factors, severity biomarkers, severity indices, health-care utilization, management strategies, and outcomes of AP patients. Between November 2015 and September 2016, a total of 20 sites (8 in the United States, 5 in Europe, 3 in South America, 2 in Mexico and 2 in India) prospectively enrolled 509 AP patients. All data were entered into the REDCap (Research Electronic Data Capture) database by participating centers and systematically reviewed by the coordinating site (University of Pittsburgh). The approaches and methodology are described in detail, along with an interim report on the demographic results. APPRENTICE, an international collaboration of tertiary AP centers throughout the world, has demonstrated the feasibility of building a large, prospective, multicenter patient registry to study AP. Analysis of the collected data may provide a greater understanding of AP and APPRENTICE will serve as a future platform for randomized clinical trials.

  5. Primary Immune Deficiency Treatment Consortium (PIDTC) report.

    PubMed

    Griffith, Linda M; Cowan, Morton J; Notarangelo, Luigi D; Kohn, Donald B; Puck, Jennifer M; Pai, Sung-Yun; Ballard, Barbara; Bauer, Sarah C; Bleesing, Jack J H; Boyle, Marcia; Brower, Amy; Buckley, Rebecca H; van der Burg, Mirjam; Burroughs, Lauri M; Candotti, Fabio; Cant, Andrew J; Chatila, Talal; Cunningham-Rundles, Charlotte; Dinauer, Mary C; Dvorak, Christopher C; Filipovich, Alexandra H; Fleisher, Thomas A; Bobby Gaspar, Hubert; Gungor, Tayfun; Haddad, Elie; Hovermale, Emily; Huang, Faith; Hurley, Alan; Hurley, Mary; Iyengar, Sumathi; Kang, Elizabeth M; Logan, Brent R; Long-Boyle, Janel R; Malech, Harry L; McGhee, Sean A; Modell, Fred; Modell, Vicki; Ochs, Hans D; O'Reilly, Richard J; Parkman, Robertson; Rawlings, David J; Routes, John M; Shearer, William T; Small, Trudy N; Smith, Heather; Sullivan, Kathleen E; Szabolcs, Paul; Thrasher, Adrian; Torgerson, Troy R; Veys, Paul; Weinberg, Kenneth; Zuniga-Pflucker, Juan Carlos

    2014-02-01

    The Primary Immune Deficiency Treatment Consortium (PIDTC) is a network of 33 centers in North America that study the treatment of rare and severe primary immunodeficiency diseases. Current protocols address the natural history of patients treated for severe combined immunodeficiency (SCID), Wiskott-Aldrich syndrome, and chronic granulomatous disease through retrospective, prospective, and cross-sectional studies. The PIDTC additionally seeks to encourage training of junior investigators, establish partnerships with European and other International colleagues, work with patient advocacy groups to promote community awareness, and conduct pilot demonstration projects. Future goals include the conduct of prospective treatment studies to determine optimal therapies for primary immunodeficiency diseases. To date, the PIDTC has funded 2 pilot projects: newborn screening for SCID in Navajo Native Americans and B-cell reconstitution in patients with SCID after hematopoietic stem cell transplantation. Ten junior investigators have received grant awards. The PIDTC Annual Scientific Workshop has brought together consortium members, outside speakers, patient advocacy groups, and young investigators and trainees to report progress of the protocols and discuss common interests and goals, including new scientific developments and future directions of clinical research. Here we report the progress of the PIDTC to date, highlights of the first 2 PIDTC workshops, and consideration of future consortium objectives. Published by Mosby, Inc.

  6. Preliminary study of fusion reactor: Solution of Grad Shapranov equation

    NASA Astrophysics Data System (ADS)

    Setiawan, Y.; Fermi, N.; Su'ud, Z.

    2012-06-01

    Nuclear fussion is prospective energy sources for the future due to the abundance of the fuel and can be categorized and clean energy sources. The problem is how to contain very hot plasma of temperature few hundreed million degrees safety and reliably. Tokamax type fussion reactors is considered as the most prospective concept. To analyze the plasma confining process and its movement Grad-Shavranov equation must be solved. This paper discuss about solution of Grad-Shavranov equation using Whittaker function. The formulation is then applied to the ITER design and example.

  7. Progress and Prospects for Genetic Modification of Nonhuman Primate Models in Biomedical Research

    PubMed Central

    Chan, Anthony W. S.

    2013-01-01

    The growing interest of modeling human diseases using genetically modified (transgenic) nonhuman primates (NHPs) is a direct result of NHPs (rhesus macaque, etc.) close relation to humans. NHPs share similar developmental paths with humans in their anatomy, physiology, genetics, and neural functions; and in their cognition, emotion, and social behavior. The NHP model within biomedical research has played an important role in the development of vaccines, assisted reproductive technologies, and new therapies for many diseases. Biomedical research has not been the primary role of NHPs. They have mainly been used for safety evaluation and pharmacokinetics studies, rather than determining therapeutic efficacy. The development of the first transgenic rhesus macaque (2001) revolutionized the role of NHP models in biomedicine. Development of the transgenic NHP model of Huntington's disease (2008), with distinctive clinical features, further suggested the uniqueness of the model system; and the potential role of the NHP model for human genetic disorders. Modeling human genetic diseases using NHPs will continue to thrive because of the latest advances in molecular, genetic, and embryo technologies. NHPs rising role in biomedical research, specifically pre-clinical studies, is foreseeable. The path toward the development of transgenic NHPs and the prospect of transgenic NHPs in their new role in future biomedicine needs to be reviewed. This article will focus on the advancement of transgenic NHPs in the past decade, including transgenic technologies and disease modeling. It will outline new technologies that may have significant impact in future NHP modeling and will conclude with a discussion of the future prospects of the transgenic NHP model. PMID:24174443

  8. Recent and future liquid metal experiments on homogeneous dynamo action and magnetic instabilities

    NASA Astrophysics Data System (ADS)

    Stefani, Frank; Gerbeth, Gunter; Giesecke, Andre; Gundrum, Thomas; Kirillov, Oleg; Seilmayer, Martin; Gellert, Marcus; Rüdiger, Günther; Gailitis, Agris

    2011-10-01

    The present status of the Riga dynamo experiment is summarized and the prospects for its future exploitation are evaluated. We further discuss the plans for a large-scale precession driven dynamo experiment to be set-up in the framework of the new installation DRESDYN (DREsden Sodium facility for dynamo and thermohydraulic studies) at Helmholtz-Zentrum Dresden-Rossendorf. We report recent investigations of the magnetorotational instability and the Tayler instability and sketch the plans for another large-scale liquid sodium facility devoted to the combined study of both effects.

  9. Lacking evidence for performance of implants used for proximal femoral fractures - A systematic review.

    PubMed

    Nyholm, Anne Marie; Palm, Henrik; Malchau, Henrik; Troelsen, Anders; Gromov, Kirill

    2016-03-01

    Evaluation of the long-term performance of implants used in trauma surgery relies on post-marked clinical studies since no registry based implant assessment exists. The purpose of this study was to evaluate the evidence of performance of implants currently used for treating proximal femoral fractures (PFF) in Denmark. PubMed was searched for clinical studies on primary PFF with follow-up ≥12 months, reporting implant-related failure and evaluating one of following: DHS, CHS, HipLoc, Gamma3, IMHS, InterTan, PFN, PFNA or PTN. English language and publication date after 1st of January 1990. All studies were evidence level II or III. 30 publications for SHS were found: 13 of CHS, 15 of DHS and 2 of HipLoc. In total CHS was evaluated in 1110 patients (900 prospectively), DHS in 2486 (567 prospectively) and HipLoc in 251 (all prospectively). Fifty-four publications for nails were found: 13 of Gamma3, 7 of IMHS, 5 of InterTan, 10 of PFN, 24 of PFNA and 0 of PTN. In total Gamma3 was evaluated in 1088 patients (829 prospectively), IMHS in 1543 (210 prospectively), InterTan in 595 (585 prospectively), PFN in 716 (557 prospectively), PFNA in 1762 (1018 prospectively) and PTN in 0. The clinical evidence behind the current implants used for proximal femoral fractures is weak considering the number of implants used worldwide. Sporadic evaluation is not sufficient to identify long term problems. A systematic post market surveillance of implants used for fracture treatment, preferable by a national register, is necessary in the future. Copyright © 2016 Elsevier Ltd. All rights reserved.

  10. JenaValve.

    PubMed

    Treede, Hendrik; Rastan, Ardawan; Ferrari, Markus; Ensminger, Stephan; Figulla, Hans-Reiner; Mohr, Friedrich-Wilhelm

    2012-09-01

    The JenaValve is a next-generation TAVI device which consists of a well-proven porcine root valve mounted on a low-profile nitinol stent. Feeler guided positioning and clip fixation on the diseased leaflets allow for anatomically correct implantation of the device without rapid pacing. Safety and efficacy of transapical aortic valve implantation using the JenaValve were evaluated in a multicentre prospective study that showed good short and midterm results. The valve was CE-mark released in Europe in September 2011. A post-market registry ensures on-going and prospective data collection in "real-world" patients. The transfemoral JenaValve delivery system will be evaluated in a first-in-man study in the near future.

  11. Advances in low-level jet research and future prospects

    NASA Astrophysics Data System (ADS)

    Liu, Hongbo; He, Mingyang; Wang, Bin; Zhang, Qinghong

    2014-02-01

    The low-level jet (LLJ) is closely related to severe rainfall events, air pollution, wind energy utilization, aviation safety, sandstorms, forest fire, and other weather and climate phenomena. Therefore, it has attracted considerable attention since its discovery. Scientists have carried out many studies on LLJs and made significant achievements during the past five or six decades. This article summarizes and assesses the current knowledge on this subject, and focuses in particular on three aspects: 1) LLJ classification, definition, distribution, and structure; 2) LLJ formation and evolutionary mechanisms; and 3) relationships between LLJ and rainfall, as well as other interdisciplinary fields. After comparing the status of LLJ research at home (China) and abroad, we then discuss the shortcomings of LLJ research in China. We suggest that this includes: coarse definitions of the LLJ, lack of observations and inadequate quality control, few thorough explorations of LLJ characteristics and formation mechanisms, and limited studies in interdisciplinary fields. The future prospects for several LLJ research avenues are also speculated.

  12. Temporal distance and discrimination: an audit study in academia.

    PubMed

    Milkman, Katherine L; Akinola, Modupe; Chugh, Dolly

    2012-07-01

    Through a field experiment set in academia (with a sample of 6,548 professors), we found that decisions about distant-future events were more likely to generate discrimination against women and minorities (relative to Caucasian males) than were decisions about near-future events. In our study, faculty members received e-mails from fictional prospective doctoral students seeking to schedule a meeting either that day or in 1 week; students' names signaled their race (Caucasian, African American, Hispanic, Indian, or Chinese) and gender. When the requests were to meet in 1 week, Caucasian males were granted access to faculty members 26% more often than were women and minorities; also, compared with women and minorities, Caucasian males received more and faster responses. However, these patterns were essentially eliminated when prospective students requested a meeting that same day. Our identification of a temporal discrimination effect is consistent with the predictions of construal-level theory and implies that subtle contextual shifts can alter patterns of race- and gender-based discrimination.

  13. History, problems, and prospects of Islamic insurance (Takaful) in Bangladesh.

    PubMed

    Khan, Issa; Rahman, Noor Naemah Binti Abdul; Yusoff, Mohd Yakub Zulkifli Bin Mohd; Nor, Mohd Roslan Bin Mohd

    2016-01-01

    This study explains the history, current problems, and future possibilities of Islamic insurance (takaful) in Bangladesh. To articulate these issues, the researcher has adopted the qualitative method, and data has been collected through secondary sources i.e. articles, books, and online resources. The study reveals that Islamic insurance in Bangladesh is regulated by the Insurance Act 2010 which is contradictory with Islamic insurance causing numerous problems for Islamic insurance. This study also points out that Islamic insurance is a fast growing industry with huge prospects in Bangladesh. The government should introduce separate regulations for both Islamic and conventional insurance. The research concludes with suggestions for the further development of Islamic insurance in Bangladesh.

  14. Prospective Teachers' Perspectives on Mathematics Teaching and Learning: Lens for Interpreting Experiences in a Standards-Based Mathematics Course

    ERIC Educational Resources Information Center

    Chamberlin, Michelle T.

    2013-01-01

    In a mathematics course for prospective elementary teachers, we strove to model standards-based pedagogy. However, an end-of-class reflection revealed the prospective teachers were considering incorporating standards-based strategies in their future classrooms in ways different from our intent. Thus, we drew upon the framework presented by Simon,…

  15. Coding of Stimuli by Animals: Retrospection, Prospection, Episodic Memory and Future Planning

    ERIC Educational Resources Information Center

    Zentall, Thomas R.

    2010-01-01

    When animals code stimuli for later retrieval they can either code them in terms of the stimulus presented (as a retrospective memory) or in terms of the response or outcome anticipated (as a prospective memory). Although retrospective memory is typically assumed (as in the form of a memory trace), evidence of prospective coding has been found…

  16. The Royal Road to Time: How Understanding of the Evolution of Time in the Brain Addresses Memory, Dreaming, Flow, and Other Psychological Phenomena.

    PubMed

    Hancock, Peter A

    2015-01-01

    It has been claimed that dreams are the royal road to the unconscious mind. The present work argues that dreams and associated brain states such as memory, attention, flow, and perhaps even consciousness itself arise from diverse conflicts over control of time in the brain. Dreams are the brain's offline efforts to distill projections of the future, while memory represents the vestiges of the past successes and survived failures of those and other conscious projections. Memory thus acts to inform and improve the prediction of possible future states through the use of conscious prospects (planning) and unconscious prospective memory (dreams). When successful, these prospects result in states of flow for conscious planning and déjà vu for its unconscious comparator. In consequence, and contrary to normal expectation, memory is overwhelmingly oriented to deal with the future. Consciousness is the comparable process operating in the present moment. Thus past, present, and future are homeomorphic with the parts of memory (episodic and autobiographical) that recall a personal past, consciousness, and the differing dimensions of prospective memory to plan for future circumstances, respectively. Dreaming (i.e., unconscious prospective memory), has the luxury to run multiple "what if" simulations of many possible futures, essentially offline. I explicate these propositions and their relations to allied constructs such as déjà vu and flow. More generally, I propose that what appear to us as a range of normal psychological experiences are actually manifestations of an ongoing pathological battle for control within the brain. The landscape of this conflict is time. I suggest that there are at least 3 general systems bidding for this control, and in the process of evolution, each system has individually conferred a sequentially increasing survival advantage, but only at the expense of a still incomplete functional integration. Through juxtaposition of these respective brain systems, I endeavor to resolve some fundamental paradoxes and conundrums expressed in the basic psychological and behavioral processes of sleep, consciousness, and memory. The implication of this conceptual framework for the overall conception of time is then briefly adumbrated.

  17. Comparisons of Patient Demographics in Prospective Sports, Shoulder, and National Database Initiatives.

    PubMed

    Saltzman, Bryan M; Cvetanovich, Gregory L; Bohl, Daniel D; Cole, Brian J; Bach, Bernard R; Romeo, Anthony A

    2016-09-01

    There has been increased emphasis in orthopaedics on high-quality prospective research to provide evidence-based treatment guidelines, particularly in sports medicine/shoulder surgery. The external validity of these studies has not been established, and the generalizability of the results to clinical practice in the United States is unknown. Comparison of patient demographics in major prospective studies of arthroscopic sports and shoulder surgeries to patients undergoing the same procedures in the National Surgical Quality Improvement Program (NSQIP) database will show substantial differences to question the generalizability and external validity of those studies. Cross-sectional study; Level of evidence, 3. This study utilized patients undergoing arthroscopic anterior cruciate ligament reconstruction (ACLR), meniscectomy (MX), rotator cuff repair (RCR), and shoulder stabilization (SS) from the NSQIP database (2005-2013). Two prospective studies (either randomized controlled trials or, in 1 case, a major cohort study) were identified for each of the 4 procedures for comparison. Demographic variables available for comparison in both the identified prospective studies and the NSQIP included age, sex, and body mass index (BMI). From the NSQIP database, 5576 ACLR patients, 18,882 MX patients, 7282 RCR patients, and 993 SS patients were identified. The comparison clinical studies included cohort sizes as follows: ACLR, n = 121 and 2683; MX, n = 146 and 330; RCR, n = 90 and 103; SS, n = 88 and 196. Age differed significantly between the NSQIP and the patients in 6 of the 8 prospective clinical studies. Sex differed significantly between the NSQIP and the patients in 7 of the 8 prospective clinical studies. BMI differed significantly between the NSQIP and the patients of all 4 of the prospective clinical studies that reported this demographic variable. Significant differences exist for patient age, sex, and BMI between patients included in major sports medicine/shoulder prospective studies and corresponding patients undergoing the same procedures in a nationwide database of academic and community centers in the United States. Future work is needed to understand whether major prospective clinical studies-frequently performed in high-volume, specialized practices-are truly indicative of the types of patients treated and expected results in the general orthopaedic practice. This study additionally argues for the importance of initiating a national registry dedicated to patients undergoing orthopaedic procedures in the United States.

  18. The universality and the future prospects of physiological energetics: Reply to comments on "Physics of metabolic organization".

    PubMed

    Jusup, Marko; Sousa, Tânia; Domingos, Tiago; Labinac, Velimir; Marn, Nina; Wang, Zhen; Klanjšček, Tin

    2017-03-01

    In response to the comments on review "Physics of metabolic organization", we discuss the universality and the future prospects of physiological energetics. The topics range from the role of entropy in modeling living organisms to the apparent ubiquity of the von Bertalanffy curve, and the potential applications of the theory in yet unexplored domains. Tradeoffs in outreach to non-specialists are also briefly considered. Copyright © 2017 Elsevier B.V. All rights reserved.

  19. The future orientation of constructive memory: an evolutionary perspective on therapeutic hypnosis and brief psychotherapy.

    PubMed

    Rossi, Ernest; Erickson-Klein, Roxanna; Rossi, Kathryn

    2008-04-01

    We explore a new distinction between the future, prospective memory system being investigated in current neuroscience and the past, retrospective memory system, which was the original theoretical foundation of therapeutic hypnosis, classical psychoanalysis, and psychotherapy. We then generalize a current evolutionary theory of sleep and dreaming, which focuses on the future, prospective memory system, to conceptualize a new evolutionary perspective on therapeutic hypnosis and brief psychotherapy. The implication of current neuroscience research is that activity-dependent gene expression and brain plasticity are the psychobiological basis of adaptive behavior, consciousness, and creativity in everyday life as well as psychotherapy. We summarize a case illustrating how this evolutionary perspective can be used to quickly resolve problems with past obstructive procrastination in school to facilitate current and future academic success.

  20. Predictors of Dropout From Inpatient Substance Use Treatment: A Prospective Cohort Study

    PubMed Central

    Andersson, Helle Wessel; Steinsbekk, Aslak; Walderhaug, Espen; Otterholt, Eli; Nordfjærn, Trond

    2018-01-01

    Introduction: Dropout from inpatient treatment for substance use disorder (SUD) is an ongoing challenge. The aim of this study was to identify demographic, substance use, and psychological factors that predict dropout from postdetoxification inpatient SUD treatment. Materials and methods: A total of 454 patients from 5 inpatient SUD centers in Central Norway were consecutively included in this naturalistic, prospective cohort study. Results: A total of 132 patients (28%) did not complete the planned treatment stay (dropped out). Cox regression analysis showed that higher levels of intrinsic motivation for changing personal substance use reduced the dropout risk (adjusted hazard ratio [adjHR]: 0.62, 95% confidence interval [CI]: 0.48-0.79). Higher levels of mental distress were associated with an increased risk for dropout (adjHR: 1.48, 95% CI: 1.11-1.97). Conclusions: The role of mental health and motivation in reducing dropout risk from inpatient SUD treatment should be targeted in future prospective intervention studies. PMID:29531472

  1. Weight Loss and Malnutrition in Patients with Parkinson's Disease: Current Knowledge and Future Prospects

    PubMed Central

    Ma, Kai; Xiong, Nian; Shen, Yan; Han, Chao; Liu, Ling; Zhang, Guoxin; Wang, Luxi; Guo, Shiyi; Guo, Xingfang; Xia, Yun; Wan, Fang; Huang, Jinsha; Lin, Zhicheng; Wang, Tao

    2018-01-01

    Parkinson's Disease (PD) is currently considered a systemic neurodegenerative disease manifested with not only motor but also non-motor symptoms. In particular, weight loss and malnutrition, a set of frequently neglected non-motor symptoms, are indeed negatively associated with the life quality of PD patients. Moreover, comorbidity of weight loss and malnutrition may impact disease progression, giving rise to dyskinesia, cognitive decline and orthostatic hypotension, and even resulting in disability and mortality. Nevertheless, the underlying mechanism of weight loss and malnutrition in PD remains obscure and possibly involving multitudinous, exogenous or endogenous, factors. What is more, there still does not exist any weight loss and malnutrition appraision standards and management strategies. Given this, here in this review, we elaborate the weight loss and malnutrition study status in PD and summarize potential determinants and mechanisms as well. In conclusion, we present current knowledge and future prospects of weight loss and malnutrition in the context of PD, aiming to appeal clinicians and researchers to pay a closer attention to this phenomena and enable better management and therapeutic strategies in future clinical practice. PMID:29403371

  2. Three decades of Cognition & Emotion: A brief review of past highlights and future prospects.

    PubMed

    Rothermund, Klaus; Koole, Sander L

    2018-02-01

    Over the past three decades, Cognition & Emotion has been one of the world's leading outlets for emotion research. In this article, we review past highlights of and future prospects for the journal. Our tour of history covers three periods: The first period, from 1987 to 1999, was a pioneering era in which cognitive theories began to be applied to the scientific analysis of emotion. The second period, from 2000 to 2007, was characterised by a sharp increase in the number of empirical research papers, a lot of which were concerned with automatic processing biases and their implications for clinical psychology. During the third period, from 2008 to 2017, a new focus emerged on self-regulatory processes and their implications for emotion. We then turn to the present profile of Cognition & Emotion and introduce our new editorial team. Finally, we consider how the journal's future success can be continued and increased by a) providing authors with fast and high-quality feedback; b) offering attractive publication formats, including the newly introduced Registered Reports for pre-registered studies; and c) consolidating key methodological paradigms with reproducible findings.

  3. Iron Isotopes in Spherical Hematite and Goethite Concretions from the Navajo Sandstone (Utah, USA): A Prospective Study for "Martian Blueberries"

    NASA Astrophysics Data System (ADS)

    Busigny, V.; Dauphas, N.

    2006-03-01

    Iron isotopes of terrestrial hematite and goethite concretions provide clues on fluid transport, reservoir sizes, redox variations and biotic versus abiotic processes. This opens several avenues of research for future work on Martian blueberries.

  4. Lattice Studies of Hyperon Spectroscopy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Richards, David G.

    2016-04-01

    I describe recent progress at studying the spectrum of hadrons containing the strange quark through lattice QCD calculations. I emphasise in particular the richness of the spectrum revealed by lattice studies, with a spectrum of states at least as rich as that of the quark model. I conclude by prospects for future calculations, including in particular the determination of the decay amplitudes for the excited states.

  5. The Relationship between Doctoral Completion Time, Gender, and Future Salary Prospects for Physical Scientists

    NASA Astrophysics Data System (ADS)

    Potvin, Geoff; Tai, Robert H.

    2012-03-01

    Drawing from a national survey of Ph.D.-holding physical scientists, we present evidence that doctoral completion time is a strong predictor of future salary prospects: each additional year in graduate school corresponds to a substantially lower average salary. This is true even while controlling for typical measures of scientific merit (grant funding and publication rates) and several other structural and career factors expected to influence salaries. Extending this picture to include gender effects, we show that women earn significantly less than men overall and experience no effect of doctoral completion time on their salaries, while men see a significant gain in salary stemming from earlier completion times. Doctoral completion time is shown to be largely unconnected to measures of prior academic success, research independence, and scientific merit suggesting that doctoral completion time is, to a great extent, out of the control of individual graduate students. Nonetheless, it can be influential on an individual's future career prospects, as can gender-related effects.

  6. Metal hydride hydrogen compression: recent advances and future prospects

    NASA Astrophysics Data System (ADS)

    Yartys, Volodymyr A.; Lototskyy, Mykhaylo; Linkov, Vladimir; Grant, David; Stuart, Alastair; Eriksen, Jon; Denys, Roman; Bowman, Robert C.

    2016-04-01

    Metal hydride (MH) thermal sorption compression is one of the more important applications of the MHs. The present paper reviews recent advances in the field based on the analysis of the fundamental principles of this technology. The performances when boosting hydrogen pressure, along with two- and three-step compression units, are analyzed. The paper includes also a theoretical modelling of a two-stage compressor aimed at describing the performance of the experimentally studied systems, their optimization and design of more advanced MH compressors. Business developments in the field are reviewed for the Norwegian company HYSTORSYS AS and the South African Institute for Advanced Materials Chemistry. Finally, future prospects are outlined presenting the role of the MH compression in the overall development of the hydrogen-driven energy systems. The work is based on the analysis of the development of the technology in Europe, USA and South Africa.

  7. Metal hydride hydrogen compression: Recent advances and future prospects

    DOE PAGES

    Bowman, Jr., Robert C.; Yartys, Volodymyr A.; Lototskyy, Mykhaylo V.; ...

    2016-03-17

    Metal hydride (MH) thermal sorption compression is one of the more important applications of the metal hydrides. The present paper reviews recent advances in the field based on the analysis of the fundamental principles of this technology. The performances when boosting hydrogen pressure, along with two- and three-step compression units are analyzed. The paper includes also a theoretical modeling of a two-stage compressor aimed at both describing the performance of the experimentally studied systems, but, also, on their optimization and design of more advanced MH compressors. Business developments in the field are reviewed for the Norwegian company HYSTORSYS AS andmore » the South African Institute for Advanced Materials Chemistry. Finally, future prospects are outlined presenting the role of the metal hydride compression in the overall development of the hydrogen driven energy systems. Lastly, the work is based on the analysis of the development of the technology in Europe, USA and South Africa.« less

  8. 3D and 4D Bioprinting of the Myocardium: Current Approaches, Challenges, and Future Prospects

    PubMed Central

    Ong, Chin Siang; Nam, Lucy; Ong, Kingsfield; Krishnan, Aravind; Huang, Chen Yu; Fukunishi, Takuma

    2018-01-01

    3D and 4D bioprinting of the heart are exciting notions in the modern era. However, myocardial bioprinting has proven to be challenging. This review outlines the methods, materials, cell types, issues, challenges, and future prospects in myocardial bioprinting. Advances in 3D bioprinting technology have significantly improved the manufacturing process. While scaffolds have traditionally been utilized, 3D bioprinters, which do not require scaffolds, are increasingly being employed. Improved understanding of the cardiac cellular composition and multiple strategies to tackle the issues of vascularization and viability had led to progress in this field. In vivo studies utilizing small animal models have been promising. 4D bioprinting is a new concept that has potential to advance the field of 3D bioprinting further by incorporating the fourth dimension of time. Clinical translation will require multidisciplinary collaboration to tackle the pertinent issues facing this field. PMID:29850546

  9. Modern plant metabolomics: Advanced natural product gene discoveries, improved technologies, and future prospects

    DOE PAGES

    Sumner, Lloyd W.; Lei, Zhentian; Nikolau, Basil J.; ...

    2014-10-24

    Plant metabolomics has matured and modern plant metabolomics has accelerated gene discoveries and the elucidation of a variety of plant natural product biosynthetic pathways. This study highlights specific examples of the discovery and characterization of novel genes and enzymes associated with the biosynthesis of natural products such as flavonoids, glucosinolates, terpenoids, and alkaloids. Additional examples of the integration of metabolomics with genome-based functional characterizations of plant natural products that are important to modern pharmaceutical technology are also reviewed. This article also provides a substantial review of recent technical advances in mass spectrometry imaging, nuclear magnetic resonance imaging, integrated LC-MS-SPE-NMR formore » metabolite identifications, and x-ray crystallography of microgram quantities for structural determinations. The review closes with a discussion on the future prospects of metabolomics related to crop species and herbal medicine.« less

  10. Effectiveness of a Constructivist Approach to Science Instruction for Prospective Elementary Teachers

    NASA Astrophysics Data System (ADS)

    Liang, Ling L.; Gabel, Dorothy L.

    2005-08-01

    This study examines the effectiveness of a new constructivist curriculum model (Powerful Ideas in Physical Science) in improving prospective teachers’ understanding of science concepts, in fostering a learning environment supporting conceptual understanding, and in promoting positive attitudes toward learning and teaching science and chemistry in particular. A non-equivalent pretest post-test control-group design was employed. Analysis of covariance and repeated-measures analyses of variance were performed to analyze the scores on concept tests and attitude surveys. Data from videotaped observations of laboratory sessions and interviews of prospective teachers were analyzed by employing a naturalistic inquiry method to provide insights into the process of science learning and teaching for the teacher trainees. The interpretations were made based on the findings that could be corroborated by both methodologies. Conclusions and limitations of the present study as well as recommendations for future implementation of constructivist science curriculum in general are also included.

  11. THE STATE OF AUDIOVISUAL TECHNOLOGY--1961-1966, MONOGRAPH NO. 3.

    ERIC Educational Resources Information Center

    GODFREY, ELEANOR P.

    THE USE OF AUDIOVISUAL TECHNOLOGY OVER A SIX YEAR PERIOD WAS STUDIED. FROM A BASE OF 2,927 SCHOOL DISTRICTS, 238 DISTRICTS WERE STUDIED TO DETERMINE THE RESOURCES AVAILABLE, THE EXTENT OF USE OF THESE RESOURCES, FACTORS WHICH ENCOURAGE OR INHIBIT USE, AND PROSPECTS FOR THE FUTURE. ESTIMATES OF AMOUNTS OF ELEVEN ITEMS OF EQUIPMENT AND FIVE…

  12. What Criteria Should Policymakers Use for Assisting Households with Educational Expenditure? The Case of Urban Bangladesh

    ERIC Educational Resources Information Center

    Shafiq, M. Najeeb

    2010-01-01

    Low household expenditure on education compromises the learning and future labor market prospects of children. This study provides an empirical framework for determining the criteria that South Asian policymakers can use for assisting households with educational expenditure. A case study of urban Bangladesh using tobit and hurdle regression…

  13. Higher Education as a Field of Study: Some Future Prospects. ASHE 1986 Annual Meeting Paper.

    ERIC Educational Resources Information Center

    Cooper, Jack H.

    Problems and perspectives about the college professoriate are discussed. Attention is directed to: organization and location of graduate programs; enrollment declines and fluctuation; scholarly activities of professors; consulting and field work; and teaching. One of the recent developments of higher education as a field of study has been that…

  14. Problems with Coursebooks in EFL Classrooms: Prospective Teachers' Opinions

    ERIC Educational Resources Information Center

    Arikan, Arda

    2009-01-01

    In today's classrooms, coursebooks remain as the major instructional instrument and resource and effectiveness and quality of coursebooks must be studied in their actual classroom use. In this study, opinions of future teachers of English are collected and analyzed to shed light on what happens in Turkish EFL classrooms in regards to the use of…

  15. Telecommunication Policies in Seventeen Countries: Propects for Future Competitive Access.

    ERIC Educational Resources Information Center

    Eward, Ronald S.

    This document is a review and study of current and prospective telecommunication policies in 17 countries with regard to the competitive market access those policies foster or promise. It explores the policies of each country toward information flow that will also have an impact on international competition. The aim of the study is to identify the…

  16. Review of the origin of sulphur in DN-1 discharge and its implication for future development, Dauin prospect, central Philippines

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bayrante, L.F.; Hermoso, D.Z.; Candelaria, M.R.

    1997-12-31

    Well DN-1, the first exploratory well of the Dauin geothermal prospect discharged in 1983 substantial quantities of sulphur with a near-neutral pH fluid (pH 6.4 to 7.2) containing maximum chloride levels of 3,300 mg/kg, SO{sub 4} of 300 mg/kg; and high CO{sub 2} and H{sub 2}S relative to the production wells in Palinpinon Field to the north. The chemistry of DN-1 discharge-fluid and the origin of sulphur have been the cause of apprehension for any future development due to concerns on the presence of a possible acid resource southeast of Cuernos de Negros. A reinterpretation of the previous and newmore » surface data was undertaken in 1992 and 1996, including the origin of sulphur, to evaluate the potential of Dauin for development. The results indicate that the sulphur in DN-1 is formed from partial oxidation of hydrogen sulphide derived from the neutralised-acid fluids formed by sulphur hydrolysis at shallow levels but distant from DN-1. The study argues for the presence of near neutral exploitable resource in the prospect area.« less

  17. Remote sensing and disease control in China: past, present and future

    PubMed Central

    2013-01-01

    Satellite measurements have distinct advantages over conventional ground measurements because they can collect the information repeatedly and automatically. Since 1970 globally and 1985 in China, the availability of remote sensing (RS) techniques has steadily grown and they are becoming increasingly important to improve our understanding of human health. This paper gives the first detailed overview on the developments of RS applications for disease control in China. The problems, challenges and future directions are also discussed with an aim of guiding prospective studies. PMID:23311958

  18. Green space propulsion: Opportunities and prospects

    NASA Astrophysics Data System (ADS)

    Gohardani, Amir S.; Stanojev, Johann; Demairé, Alain; Anflo, Kjell; Persson, Mathias; Wingborg, Niklas; Nilsson, Christer

    2014-11-01

    Currently, toxic and carcinogenic hydrazine propellants are commonly used in spacecraft propulsion. These propellants impose distinctive environmental challenges and consequential hazardous conditions. With an increasing level of future space activities and applications, the significance of greener space propulsion becomes even more pronounced. In this article, a selected number of promising green space propellants are reviewed and investigated for various space missions. In-depth system studies in relation to the aforementioned propulsion architectures further unveil possible approaches for advanced green propulsion systems of the future.

  19. Psoriasis increases risk of new-onset atrial fibrillation: a systematic review and meta-analysis of prospective observational studies.

    PubMed

    Upala, Sikarin; Shahnawaz, Afeefa; Sanguankeo, Anawin

    2017-08-01

    Psoriasis is a common chronic immune-mediated dermatological disease that increases the risk of cardiovascular disease. We conducted a systematic review and meta-analysis to evaluate the association between psoriasis and atrial fibrillation from prospective observational studies. A comprehensive search of the databases of the MEDLINE and EMBASE was performed from inception through November 2015. The inclusion criterion was the prospective observational study that assessed the risk of new-onset atrial fibrillation in adults with psoriasis. Outcome was the adjusted hazard ratio (HR) of atrial fibrillation comparison between patients with psoriasis and controls. Pooled HR and 95% confidence intervals (CI) were calculated using a random-effects model. The initial search yielded 176 articles. Fifteen articles underwent full-length review and data were extracted from 4 observational studies. Incidence of atrial fibrillation was ascertained by cardiologist-reviewed electrocardiograms. There was a significant increased risk of new-onset atrial fibrillation in patients with psoriasis compared to controls with a pooled HR 1.42 (95%CI 1.22-1.65). Our meta-analysis of prospective studies demonstrated that patients with psoriasis have increased risk of new-onset atrial fibrillation. Future interventional studies addressing the impact of psoriasis treatment and prevention of atrial fibrillation should be performed.

  20. Prospective Industrial Linkage at Aqaba University College, Jordan

    ERIC Educational Resources Information Center

    Abu-Hamatteh, Zeid; Al-Amyan, Mozfi; Al-Azzam, Farouq

    2008-01-01

    The present study intends to examine the overall situation and the environment of Aqaba University College (AUC) in relation to industrial-educational interaction, and to discuss existing and possible future industrial linkage strategies. This article presents observations from AUC, as well as suggestions for action on industrial linkage. The…

  1. Genetics of Attention Deficit Hyperactivity Disorder: A Current Review and Future Prospects

    ERIC Educational Resources Information Center

    Levy, Florence; Hay, David A.; Bennett, Kellie S.

    2006-01-01

    While there have been significant advances in both the behaviour genetics and molecular genetics of Attention Deficit Hyperactivity Disorder (ADHD), researchers are now beginning to develop hypotheses about relationships between phenotypes and genetic mechanisms. Twin studies are able to model genetic, shared environmental and non-shared…

  2. What Does NCATE Have to Say to Future History Teachers?

    ERIC Educational Resources Information Center

    Wineburg, Sam

    2005-01-01

    According to current NCATE standards, social studies teachers must be well versed in economics, history, sociology, political science, psychology, anthropology, science and technology, and the arts. In short, they must know everything. In this article, the author dismisses these standards as totally unrealistic and argues that prospective social…

  3. Potential for forest products in interior Alaska.

    Treesearch

    George R. Sampson; Willem W.S. van Hees; Theodore S. Setzer; Richard C. Smith

    1988-01-01

    Future opportunities for producing Alaska forest products were examined from the perspective of timber supply as reported in timber inventory reports and past studies of forest products industry potential. The best prospects for increasing industrial production of forest products in interior Alaska are for softwood lumber. Current softwood lumber production in the...

  4. Heavy flavor results at RHIC - A comparative overview

    DOE PAGES

    Dong, Xin

    2012-01-01

    I review the latest heavy flavor measurements at RHIC experiments. Measurements from RHIC together with preliminary results from LHC offer us an opportunity to systematically study the sQGP medium properties. In the end, I will outlook a prospective future on precision heavy flavor measurements with detector upgrades at RHIC.

  5. Intraorganizational Career Advancement and Voluntary Turnover in a Multinational Bank in Taiwan

    ERIC Educational Resources Information Center

    Zhao, Wei; Zhou, Xueguang

    2008-01-01

    Purpose: This study aims to investigate how various aspects of intraorganizational career advancement--current career attainments, recent pace of upward mobility, and future prospect of career advancement--affect voluntary turnover, drawing empirical evidence from a multinational corporation (MNC) in Taiwan's cultural and labor market environment.…

  6. Reflections and Future Prospects for Evaluation in Human Resource Development

    ERIC Educational Resources Information Center

    Han, Heeyoung; Boulay, David

    2013-01-01

    Human resource development (HRD) evaluation has often been criticized for its limited function in organizational decision making. This article reviews evaluation studies to uncover the current status of HRD evaluation literature. The authors further discuss general evaluation theories in terms of value, use, and evaluator role to extend the…

  7. The Competitive Status of the U.S. Electronics Industry.

    ERIC Educational Resources Information Center

    National Academy of Engineering, Washington, DC. Committee on Technology and International Economic and Trade Issues.

    This eight-chapter report is one of seven industry-specific studies conducted to identify global shifts of industrial technological capacity on a sector-by-sector basis, to relate those shifts in international competitive industrial advantage to technological and other factors, and to assess future prospects for further technological change and…

  8. Prospective memory failures in aviation: effects of cue salience, workload, and individual differences.

    PubMed

    Van Benthem, Kathleen D; Herdman, Chris M; Tolton, Rani G; LeFevre, Jo-Anne

    2015-04-01

    Prospective memory allows people to complete intended tasks in the future. Prospective memory failures, such as pilots forgetting to inform pattern traffic of their locations, can have fatal consequences. The present research examined the impact of system factors (memory cue salience and workload) and individual differences (pilot age, cognitive health, and expertise) on prospective memory for communication tasks in the cockpit. Pilots (N = 101) flew a Cessna 172 simulator at a non-towered aerodrome while maintaining communication with traffic and attending to flight parameters. Memory cue salience (the prominence of cues that signal an intended action) and workload were manipulated. Prospective memory was measured as radio call completion rates. Pilots' prospective memory was adversely affected by low-salience cues and high workload. An interaction of cue salience, pilots' age, and cognitive health reflected the effects of system and individual difference factors on prospective memory failures. For example, younger pilots with low levels of cognitive health completed 78% of the radio calls associated with low-salience memory cues, whereas older pilots with low cognitive health scores completed just 61% of similar radio calls. Our findings suggest that technologies designed to signal intended future tasks should target those tasks with inherently low-salience memory cues. In addition, increasing the salience of memory cues is most likely to benefit pilots with lower levels of cognitive health in high-workload conditions.

  9. [Health education in Quebec: developments over the past decade and current prospects].

    PubMed

    Gagnon, Hélène; Valentini, Hélène

    2013-01-01

    This study examines the views of five university professors in the province of Quebec on recent trends and developments in health education, the relative importance of health education as a health promotion strategy, and future prospects. Interviews were conducted and the participants were asked to validate the findings. Despite minor differences, the participants were found to have similar views on health education. The interviews also pointed to a significant emphasis on recent developments in our understanding of the factors influencing health behaviors and the theoretical foundations underlying processes of change. However, much remains to be done to put this knowledge into practice. In Quebec, the field of health education has involved an increasingly diverse range of actors in recent years, although nurses continue to play an important role. Some feel that the emphasis on creating supportive environments for health and public policies has had a negative impact on the development of health education in Quebec. For others, we are witnessing the emergence of a more integrated system combining different health promotion strategies. In terms of future prospects, some remain pessimistic, emphasizing the potential effects of the current economic climate or the potential negative impact of the rise of therapeutic education, which may be at the expense of a more systemic approach. Others are more optimistic, arguing that the future of health education will be a matter of political will and that it will depend on the efforts of stakeholders to promote consistent and complementary measures.

  10. Psychological Factors Associated with Development of TMD: the OPPERA Prospective Cohort Study

    PubMed Central

    Fillingim, Roger B.; Ohrbach, Richard; Greenspan, Joel D.; Knott, Charles; Diatchenko, Luda; Dubner, Ronald; Bair, Eric; Baraian, Cristina; Mack, Nicole; Slade, Gary D.; Maixner, William

    2013-01-01

    Case-control studies have consistently associated psychological factors with chronic pain in general and with temporomandibular disorders (TMD) specifically. However, only a handful of prospective studies has explored whether pre-existing psychological characteristics represent risk factors for first-onset TMD. The current findings derive from the prospective cohort study of the Orofacial Pain Prospective Evaluation and Risk Assessment (OPPERA) cooperative agreement. For this study, 3,263 TMD-free participants completed a battery of psychological instruments assessing general psychological adjustment and personality, affective distress, psychosocial stress, somatic symptoms, and pain coping and catastrophizing. Study participants were then followed prospectively for an average of 2.8 years to ascertain cases of first-onset of TMD, and 2,737 provided follow-up data and were considered in the analyses of TMD onset. In bivariate and demographically-adjusted analyses, several psychological variables predicted increased risk of first-onset TMD, including reported somatic symptoms, psychosocial stress, and affective distress. Principal component analysis of 26 psychological scores was used to identify latent constructs, revealing four components: stress and negative affectivity, global psychological and somatic symptoms, passive pain coping, and active pain coping. In multivariable analyses, global psychological and somatic symptoms emerged as the most robust risk factor for incident TMD. These findings provide evidence that measures of psychological functioning can predict first-onset of TMD. Future analyses in the OPPERA cohort will determine whether these psychological factors interact with other variables to increase risk for TMD onset and persistence. PMID:24275225

  11. Stress Generation, Avoidance Coping, and Depressive Symptoms: A 10-Year Model

    PubMed Central

    Holahan, Charles J.; Moos, Rudolf H.; Holahan, Carole K.; Brennan, Penny L.; Schutte, Kathleen K.

    2011-01-01

    This study examined (a) the role of avoidance coping in prospectively generating both chronic and acute life stressors and (b) the stress-generating role of avoidance coping as a prospective link to future depressive symptoms. Participants were 1,211 late-middle-aged individuals (500 women and 711 men) assessed 3 times over a 10-year period. As predicted, baseline avoidance coping was prospectively associated with both more chronic and more acute life stressors 4 years later. Furthermore, as predicted, these intervening life stressors linked baseline avoidance coping and depressive symptoms 10 years later, controlling for the influence of initial depressive symptoms. These findings broaden knowledge about the stress-generation process and elucidate a key mechanism through which avoidance coping is linked to depressive symptoms. PMID:16173853

  12. The Reciprocal Relationship Between Sexual Victimization and Sexual Assertiveness

    PubMed Central

    Livingston, Jennifer A.; Testa, Maria; VanZile-Tamsen, Carol

    2007-01-01

    Low sexual assertiveness has been proposed as a possible mechanism through which sexual revictimization occurs, yet evidence for this has been mixed. In this study, prospective path analysis was used to examine the relationship between sexual refusal assertiveness and sexual victimization over time among a community sample of women. Results provide support for a reciprocal relationship, with historical victimization predicting low sexual assertiveness and low sexual assertiveness predicting subsequent victimization. The effect of recent sexual victimization on subsequent sexual assertiveness also was replicated prospectively. These findings suggest that strengthening sexual assertiveness may help reduce vulnerability to future victimization. PMID:17322273

  13. The reciprocal relationship between sexual victimization and sexual assertiveness.

    PubMed

    Livingston, Jennifer A; Testa, Maria; VanZile-Tamsen, Carol

    2007-03-01

    Low sexual assertiveness has been proposed as a possible mechanism through which sexual revictimization occurs, yet evidence for this has been mixed. In this study, prospective path analysis was used to examine the relationship between sexual refusal assertiveness and sexual victimization over time among a community sample of women. Results provide support for a reciprocal relationship, with historical victimization predicting low sexual assertiveness and low sexual assertiveness predicting subsequent victimization. The effect of recent sexual victimization on subsequent sexual assertiveness also was replicated prospectively. These findings suggest that strengthening sexual assertiveness may help reduce vulnerability to future victimization.

  14. Hip Strength as a Predictor of Ankle Sprains in Male Soccer Players: A Prospective Study.

    PubMed

    Powers, Christopher M; Ghoddosi, Navid; Straub, Rachel K; Khayambashi, Khalil

    2017-11-01

      Diminished hip-abductor strength has been suggested to increase the risk of noncontact lateral ankle sprains.   To determine prospectively whether baseline hip-abductor strength predicts future noncontact lateral ankle sprains in competitive male soccer players.   Prospective cohort study.   Athletic training facilities and various athletic fields.   Two hundred ten competitive male soccer players.   Before the start of the sport season, isometric hip-abductor strength was measured bilaterally using a handheld dynamometer. Any previous history of ankle sprain, body mass index, age, height, and weight were documented. During the sport season (30 weeks), ankle injury status was recorded by team medical providers. Injured athletes were further classified based on the mechanism of injury. Only data from injured athletes who sustained noncontact lateral ankle sprains were used for analysis. Postseason, logistic regression was used to determine whether baseline hip strength predicted future noncontact lateral ankle sprains. A receiver operating characteristic curve was constructed for hip strength to determine the cutoff value for distinguishing between high-risk and low-risk outcomes.   A total of 25 noncontact lateral ankle sprains were confirmed, for an overall annual incidence of 11.9%. Baseline hip-abductor strength was lower in injured players than in uninjured players ( P = .008). Logistic regression indicated that impaired hip-abductor strength increased the future injury risk (odds ratio = 1.10 [95% confidence interval = 1.02, 1.18], P = .010). The strength cutoff to define high risk was ≤33.8% body weight, as determined by receiver operating characteristic curve analysis. For athletes classified as high risk, the probability of injury increased from 11.9% to 26.7%.   Reduced isometric hip-abductor strength predisposed competitive male soccer players to noncontact lateral ankle sprains.

  15. Recent studies on the antimicrobial peptides lactoferricin and lactoferrampin.

    PubMed

    Yin, C; Wong, J H; Ng, T B

    2014-01-01

    Lactoferricin and lactoferrampin, peptides derived from the whey protein lactoferrin, are antimicrobial agents with a promising prospect and are currently one of the research focuses. In this review, a basic introduction including location and solution structures of these two peptides is given. Their biological activities encompassing antiviral, antibacterial, antifungal and anti-inflammatory activities with possible mechanisms are mentioned. In terms of modification studies, research about identification of their active derivatives and crucial amino acid residues is also discussed. Various attempts at modification of lactoferricin and lactoferrampin such as introducing big hydrophobic side-chains; employing special amino acids for synthesis; N-acetylization, amidation, cyclization and peptide chimera are summarized. The studies on lactoferricin-lactoferrampin chimera are discussed in detail. Future prospects of lactoferricin and lactoferrampin are covered.

  16. Lifetime measurements using the recoil distance method—achievements and perspectives

    NASA Astrophysics Data System (ADS)

    Krücken, R.

    2001-07-01

    The recoil distance method (RDM) for measuring pico-second nuclear level lifetimes and its use in nuclear structure studies is reviewed and perspectives for the future are presented. High precision measurements in the mass-130 region, studies of multi-phonon states in rare earth nuclei, the investigation of shape coexistence and the recently discovered phenomenon of "magnetic rotation" are reviewed. Prospects for lifetime measurements in exotic regions of nuclei such as the measurement of lifetimes in neutron rich nuclei populated via spontaneous and heavy-ion induced fission are discussed. Other prospects include the use of the RDM technique in conjunction with recoil separators. The relevance of these techniques for experiments with radioactive ion beams will be discussed.

  17. The level of leisure time physical activity is associated with work ability-a cross sectional and prospective study of health care workers.

    PubMed

    Arvidson, Elin; Börjesson, Mats; Ahlborg, Gunnar; Lindegård, Agneta; Jonsdottir, Ingibjörg H

    2013-09-17

    With increasing age, physical capacity decreases, while the need and time for recovery increases. At the same time, the demands of work usually do not change with age. In the near future, an aging and physically changing workforce risks reduced work ability. Therefore, the impact of different factors, such as physical activity, on work ability is of interest. Thus, the aim of this study was to evaluate the association between physical activity and work ability using both cross sectional and prospective analyses. This study was based on an extensive questionnaire survey. The number of participants included in the analysis at baseline in 2004 was 2.783, of whom 2.597 were also included in the follow-up in 2006. The primary outcome measure was the Work Ability Index (WAI), and the level of physical activity was measured using a single-item question. In the cross-sectional analysis we calculated the level of physical activity and the prevalence of poor or moderate work ability as reported by the participants. In the prospective analysis we calculated different levels of physical activity and the prevalence of positive changes in WAI-category from baseline to follow-up. In both the cross sectional and the prospective analyses the prevalence ratio was calculated using Generalized Linear Models. The cross-sectional analysis showed that with an increased level of physical activity, the reporting of poor or moderate work ability decreased. In the prospective analysis, participants reporting a higher level of physical activity were more likely to have made an improvement in WAI from 2004 to 2006. The level of physical activity seems to be related to work ability. Assessment of physical activity may also be useful as a predictive tool, potentially making it possible to prevent poor work ability and improve future work ability. For employers, the main implications of this study are the importance of promoting and facilitating the employees' engagement in physical activity, and the importance of the employees' maintaining a physically active lifestyle.

  18. The Army and Space: Historic Perspectives on Future Prospects.

    DTIC Science & Technology

    1986-06-06

    of the U.S. Army Command and General Staff College In partial fulfillment of the requirements for the dsgrecy MASTER OF MILITARY ART AND SCIENCE by...By__________ DDistribution/_ tAAvailnb’ility codes jAvail anId/oIr jDist Ispocial ýý 6R-tW rM.,W-MMM HO E ý- M WMM-7 MASTER OF MILITARY ART AND SCIENCE...PACU: HISTORICAL. PERSPECTIVES ON FUTURE PROSPECTS: An arialy .iy.s ,t thi. Ar ry’s early involvement in space to tind historical lessons to help guide

  19. Educational Technology in Australia: Origins, Status, Prospects.

    ERIC Educational Resources Information Center

    Wilson, Brian N.

    1989-01-01

    Discusses the field of educational technology and describes the evolution of the field in Australia. Definitions of educational technology are offered, the influence of computers is discussed, student attitudes toward educational technology in Australia are described, and prospects for the future are suggested. (10 references) (LRW)

  20. Prospective Payment and Baccalaureate Nursing Education: Projections for the Future.

    ERIC Educational Resources Information Center

    Van Ort, Suzanne; And Others

    1989-01-01

    Changes in the health care delivery system and projected changes in baccalaureate nursing education anticipated in the wake of implementation of the prospective payment system for health care services are examined. The discussion is based on the results of a national survey. (MSE)

  1. Characterization of the decision-making deficit of patients with ventromedial prefrontal cortex lesions.

    PubMed

    Bechara, A; Tranel, D; Damasio, H

    2000-11-01

    On a gambling task that models real-life decisions, patients with bilateral lesions of the ventromedial prefrontal cortex (VM) opt for choices that yield high immediate gains in spite of higher future losses. In this study, we addressed three possibilities that may account for this behaviour: (i) hypersensitivity to reward; (ii) insensitivity to punishment; and (iii) insensitivity to future consequences, such that behaviour is always guided by immediate prospects. For this purpose, we designed a variant of the original gambling task in which the advantageous decks yielded high immediate punishment but even higher future reward. The disadvantageous decks yielded low immediate punishment but even lower future reward. We measured the skin conductance responses (SCRs) of subjects after they had received a reward or punishment. Patients with VM lesions opted for the disadvantageous decks in both the original and variant versions of the gambling task. The SCRs of VM lesion patients after they had received a reward or punishment were not significantly different from those of controls. In a second experiment, we investigated whether increasing the delayed punishment in the disadvantageous decks of the original task or decreasing the delayed reward in the disadvantageous decks of the variant task would shift the behaviour of VM lesion patients towards an advantageous strategy. Both manipulations failed to shift the behaviour of VM lesion patients away from the disadvantageous decks. These results suggest that patients with VM lesions are insensitive to future consequences, positive or negative, and are primarily guided by immediate prospects. This 'myopia for the future' in VM lesion patients persists in the face of severe adverse consequences, i.e. rising future punishment or declining future reward.

  2. Children's mental time travel during mind wandering.

    PubMed

    Ye, Qun; Song, Xiaolan; Zhang, Yi; Wang, Qinqin

    2014-01-01

    The prospective bias is a salient feature of mind wandering in healthy adults, yet little is known about the temporal focus of children's mind wandering. In the present study, (I) we developed the temporal focus of mind wandering questionnaire for school-age children (TFMWQ-C), a 12-item scale with good test-retest reliability and construct validity. (II) The criterion validity was tested by thought sampling in both choice reaction time task and working memory task. A positive correlation was found between the temporal focus measured by the questionnaire and the one adopted during task-unrelated thoughts (TUTs) by thought sampling probes, especially in the trait level of future-oriented mind wandering. At the same time, children who experienced more TUTs tended to show worse behavioral performance during tasks. (III) The children in both tasks experienced more future-oriented TUTs than past-oriented ones, which was congruent with the results observed in adults; however, in contrast with previous research on adults, the prospective bias was not influenced by task demands. Together these results indicate that the prospective bias of mind wandering has emerged since the school-age (9∼13 years old), and that the relationship between mental time travel (MTT) during mind wandering and the use of cognitive resources differs between children and adults. Our study provides new insights into how this interesting feature of mind wandering may adaptively contribute to the development of children's MTT.

  3. Acute pancreatitis patient registry to examine novel therapies in clinical experience (APPRENTICE): an international, multicenter consortium for the study of acute pancreatitis

    PubMed Central

    Papachristou, Georgios I.; Machicado, Jorge D.; Stevens, Tyler; Goenka, Mahesh Kumar; Ferreira, Miguel; Gutierrez, Silvia C.; Singh, Vikesh K.; Kamal, Ayesha; Gonzalez-Gonzalez, Jose A.; Pelaez-Luna, Mario; Gulla, Aiste; Zarnescu, Narcis O.; Triantafyllou, Konstantinos; Barbu, Sorin T.; Easler, Jeffrey; Ocampo, Carlos; Capurso, Gabriele; Archibugi, Livia; Cote, Gregory A.; Lambiase, Louis; Kochhar, Rakesh; Chua, Tiffany; Tiwari, Subhash Ch.; Nawaz, Haq; Park, Walter G.; de-Madaria, Enrique; Lee, Peter J.; Wu, Bechien U.; Greer, Phil J.; Dugum, Mohannad; Koutroumpakis, Efstratios; Akshintala, Venkata; Gougol, Amir

    2017-01-01

    Background We have established a multicenter international consortium to better understand the natural history of acute pancreatitis (AP) worldwide and to develop a platform for future randomized clinical trials. Methods The AP patient registry to examine novel therapies in clinical experience (APPRENTICE) was formed in July 2014. Detailed web-based questionnaires were then developed to prospectively capture information on demographics, etiology, pancreatitis history, comorbidities, risk factors, severity biomarkers, severity indices, health-care utilization, management strategies, and outcomes of AP patients. Results Between November 2015 and September 2016, a total of 20 sites (8 in the United States, 5 in Europe, 3 in South America, 2 in Mexico and 2 in India) prospectively enrolled 509 AP patients. All data were entered into the REDCap (Research Electronic Data Capture) database by participating centers and systematically reviewed by the coordinating site (University of Pittsburgh). The approaches and methodology are described in detail, along with an interim report on the demographic results. Conclusion APPRENTICE, an international collaboration of tertiary AP centers throughout the world, has demonstrated the feasibility of building a large, prospective, multicenter patient registry to study AP. Analysis of the collected data may provide a greater understanding of AP and APPRENTICE will serve as a future platform for randomized clinical trials. PMID:28042246

  4. Academic Futures: Prospects for Post-Secondary Education.

    ERIC Educational Resources Information Center

    Shere, Waris, Ed.; Duhamel, Ronald, Ed.

    Present trends and future directions in postsecondary education in Canada and the United States are addressed in 15 essays and an introduction by Ron Duhamel. Authors and titles are as follows: "Traditional Values in the Contemporary University" (Robin H. Farquhar); "Facing the Future" (R. J. Duhamel); "Challenges to the…

  5. Future riverine nitrogen export to US coastal regions: Prospects for improving water quality amid population growth.

    EPA Science Inventory

    Excess nitrogen (N) in the environment degrades ecosystems and adversely affects human health. Here we examine predictions of contemporary (2000) and future (2030) coastal N loading in the continental US by the Nutrient Export from WaterSheds (NEWS) model. Future scenarios were b...

  6. Coordination and management of multicenter clinical studies in trauma: Experience from the PRospective Observational Multicenter Major Trauma Transfusion (PROMMTT) Study.

    PubMed

    Rahbar, Mohammad H; Fox, Erin E; del Junco, Deborah J; Cotton, Bryan A; Podbielski, Jeanette M; Matijevic, Nena; Cohen, Mitchell J; Schreiber, Martin A; Zhang, Jiajie; Mirhaji, Parsa; Duran, Sarah J; Reynolds, Robert J; Benjamin-Garner, Ruby; Holcomb, John B

    2012-04-01

    Early death due to hemorrhage is a major consequence of traumatic injury. Transfusion practices differ among hospitals and it is unknown which transfusion practices improve survival. This report describes the experience of the PRospective Observational Multicenter Major Trauma Transfusion (PROMMTT) Study Data Coordination Center in designing and coordinating a study to examine transfusion practices at ten Level 1 trauma centers in the US. PROMMTT was a multisite prospective observational study of severely injured transfused trauma patients. The clinical sites collected real-time information on the timing and amounts of blood product infusions as well as colloids and crystalloids, vital signs, initial diagnostic and clinical laboratory tests, life saving interventions and other clinical care data. Between July 2009 and October 2010, PROMMTT screened 12,561 trauma admissions and enrolled 1245 patients who received one or more blood transfusions within 6h of Emergency Department (ED) admission. A total of 297 massive transfusions were observed over the course of the study at a combined rate of 5.0 massive transfusion patients/week. PROMMTT is the first multisite study to collect real-time prospective data on trauma patients requiring transfusion. Support from the Department of Defense and collaborative expertise from the ten participating centers helped to demonstrate the feasibility of prospective trauma transfusion studies. The observational data collected from this study will be an invaluable resource for research in trauma surgery and it will guide the design and conduct of future randomized trials. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  7. Coordination and management of multicenter clinical studies in trauma: Experience from the PRospective Observational Multicenter Major Trauma Transfusion (PROMMTT) Study

    PubMed Central

    Rahbar, Mohammad H.; Fox, Erin E.; del Junco, Deborah J.; Cotton, Bryan A.; Podbielski, Jeanette M.; Matijevic, Nena; Cohen, Mitchell J.; Schreiber, Martin A.; Zhang, Jiajie; Mirhaji, Parsa; Duran, Sarah; Reynolds, Robert J.; Benjamin-Garner, Ruby; Holcomb, John B.

    2011-01-01

    Aim Early death due to hemorrhage is a major consequence of traumatic injury. Transfusion practices differ among hospitals and it is unknown which transfusion practices improve survival. This report describes the experience of the PRospective Observational Multicenter Major Trauma Transfusion (PROMMTT) Study Data Coordination Center in designing and coordinating a study to examine transfusion practices at ten Level 1 trauma centers in the U.S. Methods PROMMTT was a multisite prospective observational study of severely injured transfused trauma patients. The clinical sites collected real-time information on the timing and amounts of blood product infusions as well as colloids and crystalloids, vital signs, initial diagnostic and clinical laboratory tests, life saving interventions and other clinical care data. Results Between July 2009 and October 2010, PROMMTT screened 12,561 trauma admissions and enrolled 1,245 patients who received one or more blood transfusions within 6 hours of ED admission. A total of 297 massive transfusions were observed over the course of the study at a combined rate of 5.0 massive transfusion patients/week. Conclusion PROMMTT is the first multisite study to collect real-time prospective data on trauma patients requiring transfusion. Support from the Department of Defense and collaborative expertise from the ten participating centers helped to demonstrate the feasibility of prospective trauma transfusion studies. The observational data collected from this study will be an invaluable resource for research in trauma surgery and it will guide the design and conduct of future randomized trials. PMID:22001613

  8. The Impact of an Intensive Experience on Prospective Teachers' Perception of the Uses of Digital, Interactive Text among K-12 Students

    ERIC Educational Resources Information Center

    Stonier, Francis W.

    2012-01-01

    The purpose of this study was to measure pre-service teacher perception, awareness, and potential use of digital literacies, media, and digital interactive text in their future classrooms. The study grew from the theoretical rationales of new literacies, technological pedagogical content knowledge, and constructivism. New literacies are…

  9. Teaching Future K-8 Teachers the Language of Newton: A Case Study of Collaboration and Change in University Physics Teaching

    ERIC Educational Resources Information Center

    Briscoe, Carol; Prayaga, Chandra S.

    2004-01-01

    This interpretive case study describes a collaborative project involving a physics professor and a science educator. We report what was learned about factors that influenced the professor's development of teaching strategies, alternative to lecture, that were intended to promote prospective teachers' meaningful learning and their use of canonical…

  10. On Teaching the Scientific Complexity of Germination: A Study with Prospective Elementary Teachers

    ERIC Educational Resources Information Center

    Vidal, Manuel; Membiela, Pedro

    2014-01-01

    This study reveals and discusses the problems of future elementary teachers after they have completed a practical on germination, including the fact that such practice is conceptually more complex than is usually considered, at least when the aim is to experiment with the determinant factors for germination. In this case there seemed to be some…

  11. Prospective Associations between Youth Assets, Neighborhood Characteristics and No-Tobacco Use among Youth: Differences by Gender

    ERIC Educational Resources Information Center

    Tolma, Eleni L.; Oman, Roy F.; Vesely, Sara K.; Aspy, Cheryl B.; Boeckman, Lindsay

    2013-01-01

    The purpose of this study is to assess the relationship between youth assets and neighborhood environmental variables and future no-tobacco use among youth; examining differences by gender. Five waves of annual data were collected from 1,111 youth randomly selected to participate in the Youth Asset Study (YAS). A marginal logistic regression model…

  12. Change in reciprocity as a predictor of depressive symptoms: a prospective cohort study of Finnish women and men.

    PubMed

    Väänänen, Ari; Buunk, Abraham P; Kivimäki, Mika; Vahtera, Jussi; Koskenvuo, Markku

    2008-12-01

    The purpose of the study was to examine gender differences in the association between changes in the balance of give and take in close relationships and depressive symptoms. Data from a 5-year prospective cohort study in Finland (HeSSup Study) (N=18,445) were analyzed. After adjustment for demographic characteristics, recent negative life events, baseline depressive symptoms, hostility, and the supportiveness of social network, a shift of balance toward support receiving was a significant risk factor for future depressive symptoms among women. In contrast, men whose balance of give and take had moved toward support giving had a higher risk of future depressive symptoms than other men. When the analyses were replicated in a sub-cohort of initially non-depressed participants who lived in reciprocal relationships and had no recent life events, the results became even more pronounced among women, although not among men. We conclude that, for women, a shift in their close relationships toward support receiving may lead to increased risk of depressive symptoms, whereas for men a shift toward giving may have a parallel though less evident impact.

  13. Pharmacogenetics and pharmacogenomics in psoriasis treatment: current challenges and future prospects.

    PubMed

    Sutherland, Alison; Power, Rebecca J; Rahman, Proton; O'Rielly, Darren D

    2016-08-01

    Topical, systemic, oral disease modifying, and biologic agents are part of the armamentarium to manage psoriatic disease. The choice of therapy depends upon disease severity, relevant co-morbidities and patient preference. There is great variability in patient response with these agents, and there is still no clear method of selecting the preferred therapeutic agent for efficacy or lack of adverse events. This article will review the pharmacogenetic and pharmacogenomic targets that are currently known with respect to psoriasis vulgaris, and the most frequent co-morbidity of psoriasis, psoriatic arthritis. Presently, no clinically actionable biomarker exists for any therapeutic agent used to treat psoriasis or psoriatic arthritis. The lack of validated outcome measures and conflicting results of open-label studies conducted may be attributed to a multitude of issues that confound discovery. Consequently, studies have been underpowered to identify genes or genetic variants worth translating to clinical practice. In order to achieve a pharmacogenetic/pharmacogenomic signature, improvements in study design of future investigations are required, including carefully designed prospective studies. It is imperative to combine known clinical, serological, and molecular markers with consistent outcomes and an adequate health economic evaluation before they can be adopted widely in clinical practice.

  14. Adolescents' thoughts about parents' jobs and their importance for adolescents' future orientation.

    PubMed

    Neblett, Nicole Gardner; Cortina, Kai Schnabel

    2006-10-01

    The current study examined the relation between adolescents' perceptions of their parents' jobs and their future orientation, and tested the role of parental support. Four hundred and fifteen ninth through twelfth graders were surveyed about their parents' job rewards, self-direction, and stressors, as well as their expectations for employment and education prospects. Results indicate that perceptions of parents' rewards, self-direction, and stress predict how positively or negatively adolescents perceive the future to be. Results also suggest that higher levels of parental support may weaken the association between perceptions and future orientation when adolescents perceive their parents experience unfavorable conditions at work. These results suggest that adolescents' perceptions of parents' jobs have implications for their preparation for adulthood.

  15. Prospective study of symptom control in 133 cases of palliative care inpatients in Shatin Hospital.

    PubMed

    Lo, R S; Ding, A; Chung, T K; Woo, J

    1999-07-01

    We report a prospective study assessing the prevalence and severity of physical and nonphysical symptoms, and the benefits from treatment and intervention, in advanced cancer patients presenting to a local palliative care unit in Hong Kong. Patients were assessed by a modified version of the support team assessment schedule (STAS). The study highlighted some symptoms which needed better control, and also reinforced the team morale by demonstrating aspects where there was definite improvement. In general, the STAS was found to be practicable and acceptable by our patients and staff. The most important benefit gained from the study was the successful dissemination of the concept of audit and quality assurance throughout the unit, which is essential for continuous improvement in the future.

  16. An international prospective cohort study of mobile phone users and health (Cosmos): design considerations and enrolment.

    PubMed

    Schüz, Joachim; Elliott, Paul; Auvinen, Anssi; Kromhout, Hans; Poulsen, Aslak Harbo; Johansen, Christoffer; Olsen, Jørgen H; Hillert, Lena; Feychting, Maria; Fremling, Karin; Toledano, Mireille; Heinävaara, Sirpa; Slottje, Pauline; Vermeulen, Roel; Ahlbom, Anders

    2011-02-01

    There is continuing public and scientific interest in the possibility that exposure to radiofrequency (RF) electromagnetic fields (EMF) from mobile telephones or other wireless devices and applications might increase the risk of certain cancers or other diseases. The interest is amplified by the rapid world-wide penetration of such technologies. The evidence from epidemiological studies published to date have not been consistent and, in particular, further studies are required to identify whether longer term (well beyond 10 years) RF exposure might pose some health risk. The "Cosmos" study described here is a large prospective cohort study of mobile telephone users (ongoing recruitment of 250,000 men and women aged 18+ years in five European countries - Denmark, Finland, Sweden, The Netherlands, UK) who will be followed up for 25+ years. Information on mobile telephone use is collected prospectively through questionnaires and objective traffic data from network operators. Associations with disease risks will be studied by linking cohort members to existing disease registries, while changes in symptoms such as headache and sleep quality and of general well-being are assessed by baseline and follow-up questionnaires. A prospective cohort study conducted with appropriate diligence and a sufficient sample size, overcomes many of the shortcomings of previous studies. Its major advantages are exposure assessment prior to the diagnosis of disease, the prospective collection of objective exposure information, long-term follow-up of multiple health outcomes, and the flexibility to investigate future changes in technologies or new research questions. Copyright © 2010 Elsevier Ltd. All rights reserved.

  17. The Development of Interactive Distance Learning in Taiwan: Challenges and Prospects.

    ERIC Educational Resources Information Center

    Chu, Clarence T.

    1999-01-01

    Describes three types of interactive distance-education systems under development in Taiwan: real-time multicast systems; virtual-classroom systems; and curriculum-on-demand systems. Discusses the use of telecommunications and computer technology in higher education, problems and challenges, and future prospects. (Author/LRW)

  18. The Mathematical Preparation of Prospective Elementary Teachers: Reflections from Solving an "Interesting Problem"

    ERIC Educational Resources Information Center

    Ellis, Mark W.; Contreras, Jose; Martinez-Cruz, Armando M.

    2009-01-01

    Problem solving tasks offer valuable opportunities to strengthen prospective elementary teachers' knowledge of and disposition toward mathematics, providing them with new experiences doing mathematics. Mathematics educators can influence future instruction by modeling effective pedagogical strategies that engage students in making sense of…

  19. Can Perceptuo-Motor Skills Assessment Outcomes in Young Table Tennis Players (7-11 years) Predict Future Competition Participation and Performance? An Observational Prospective Study.

    PubMed

    Faber, Irene R; Elferink-Gemser, Marije T; Faber, Niels R; Oosterveld, Frits G J; Nijhuis-Van der Sanden, Maria W G

    2016-01-01

    Forecasting future performance in youth table tennis players based on current performance is complex due to, among other things, differences between youth players in growth, development, maturity, context and table tennis experience. Talent development programmes might benefit from an assessment of underlying perceptuo-motor skills for table tennis, which is hypothesized to determine the players' potential concerning the perceptuo-motor domain. The Dutch perceptuo-motor skills assessment intends to measure the perceptuo-motor potential for table tennis in youth players by assessing the underlying skills crucial for developing technical and tactical qualities. Untrained perceptuo-motor tasks are used as these are suggested to represent a player's future potential better than specific sport skills themselves as the latter depend on exposure to the sport itself. This study evaluated the value of the perceptuo-motor skills assessment for a talent developmental programme by evaluating its predictive validity for competition participation and performance in 48 young table tennis players (7-11 years). Players were tested on their perceptuo-motor skills once during a regional talent day, and the subsequent competition results were recorded half-yearly over a period of 2.5 years. Logistic regression analysis showed that test scores did not predict future competition participation (p >0.05). Yet, the Generalized Estimating Equations analysis, including the test items 'aiming at target', 'throwing a ball', and 'eye-hand coordination' in the best fitting model, revealed that the outcomes of the perceptuo-motor skills assessment were significant predictors for future competition results (R2 = 51%). Since the test age influences the perceptuo-motor skills assessment's outcome, another multivariable model was proposed including test age as a covariate (R2 = 53%). This evaluation demonstrates promising prospects for the perceptuo-motor skills assessment to be included in a talent development programme. Future studies are needed to clarify the predictive value in a larger sample of youth competition players over a longer period in time.

  20. The role of job strain in understanding midlife common mental disorder: a national birth cohort study.

    PubMed

    Harvey, Samuel B; Sellahewa, Dilan A; Wang, Min-Jung; Milligan-Saville, Josie; Bryan, Bridget T; Henderson, Max; Hatch, Stephani L; Mykletun, Arnstein

    2018-06-01

    Long-standing concerns exist about reverse causation and residual confounding in the prospective association between job strain and risk of future common mental disorders. We aimed to address these concerns through analysis of data collected in the UK National Child Development Study, a large British cohort study. Data from the National Child Development Study (n=6870) were analysed by use of multivariate logistic regression to investigate the prospective association between job strain variables at age 45 years and risk of future common mental disorders at age 50 years, controlling for lifetime psychiatric history and a range of other possible confounding variables across the lifecourse. Population attributable fractions were calculated to estimate the public health effect of job strain on midlife mental health. In the final model, adjusted for all measured confounders, high job demands (odds ratio 1·70, 95% CI 1·25-2·32; p=0·0008), low job control (1·89, 1·29-2·77; p=0·0010), and high job strain (2·22, 1·59-3·09; p<0·0001) remained significant independent predictors of future onset of common mental disorder. If causality is assumed, our findings suggest that 14% of new cases of common mental disorder could have been prevented through elimination of high job strain (population attributable fraction 0·14, 0·06-0·20). High job strain appears to independently affect the risk of future common mental disorders in midlife. These findings suggest that modifiable work-related risk factors might be an important target in efforts to reduce the prevalence of common mental disorders. iCare Foundation and Mental Health Branch, NSW Health. Copyright © 2018 Elsevier Ltd. All rights reserved.

  1. Depression and anxiety predict health-related quality of life in chronic obstructive pulmonary disease: systematic review and meta-analysis.

    PubMed

    Blakemore, Amy; Dickens, Chris; Guthrie, Else; Bower, Peter; Kontopantelis, Evangelos; Afzal, Cara; Coventry, Peter A

    2014-01-01

    The causal association between depression, anxiety, and health-related quality of life (HRQoL) in chronic obstructive pulmonary disease (COPD) is unclear. We therefore conducted a systematic review of prospective cohort studies that measured depression, anxiety, and HRQoL in COPD. Electronic databases (Medline, Embase, Cumulative Index to Nursing and Allied Health Literature [CINAHL], British Nursing Index and Archive, PsycINFO and Cochrane database) were searched from inception to June 18, 2013. Studies were eligible for inclusion if they: used a nonexperimental prospective cohort design; included patients with a diagnosis of COPD confirmed by spirometry; and used validated measures of depression, anxiety, and HRQoL. Data were extracted and pooled using random effects models. Six studies were included in the systematic review; of these, three were included in the meta-analysis for depression and two were included for the meta-analysis for anxiety. Depression was significantly correlated with HRQoL at 1-year follow-up (pooled r=0.48, 95% confidence interval 0.37-0.57, P<0.001). Anxiety was also significantly correlated with HRQoL at 1-year follow-up (pooled r=0.36, 95% confidence interval 0.23-0.48, P<0.001). Anxiety and depression predict HRQoL in COPD. However, this longitudinal analysis does not show cause and effect relationships between depression and anxiety and future HRQoL. Future studies should identify psychological predictors of poor HRQoL in well designed prospective cohorts with a view to isolating the mediating role played by anxiety disorder and depression.

  2. Career Satisfaction of Postdoctoral Researchers in Relation to Their Expectations for the Future

    ERIC Educational Resources Information Center

    van der Weijden, Inge; Teelken, Christine; de Boer, Moniek; Drost, Mariske

    2016-01-01

    While postdoctoral researchers (postdocs) are an increasingly important and productive group of employees in academia, they lack further career prospects and embeddedness within their organizations. This paper provides a rare glimpse into this relatively unexplored but important group. A comparative study of two Dutch universities included a…

  3. A Theoretical Assessment of Regional Development Effects on the Demand for General Education

    ERIC Educational Resources Information Center

    Iwahashi, Roki

    2007-01-01

    This study addresses a prospective aspect of general education: through general education, people obtain information about returns to their future specific education, thereby enabling them to choose fields in which they excel. According to that property of education, this paper presents a theoretical framework as a basis for understanding effects…

  4. Impact of Technological and Structural Change on Employment: Prospective Analysis 2020. Background Report.

    ERIC Educational Resources Information Center

    Christidis, Panayotis, Ed.; Hernandez, Hector, Ed.; Lievonen, Jorma, Ed.

    A study examined the role of technology in the European Union's (EU's) economy and its impacts on employment. Starting point was Technology and Employment Maps of the FUTURES project that identified main emerging technological developments (TDs) and their implications for employment. Technologies' potential impact on productivity growth and…

  5. Evaluating the Predictive Validity of Suicidal Intent and Medical Lethality in Youth

    ERIC Educational Resources Information Center

    Sapyta, Jeffrey; Goldston, David B.; Erkanli, Alaattin; Daniel, Stephanie S.; Heilbron, Nicole; Mayfield, Andrew; Treadway, S. Lyn

    2012-01-01

    Objectives: To examine whether suicidal intent and medical lethality of past suicide attempts are predictive of future attempts, the association between intent and lethality, and the consistency of these characteristics across repeated attempts among youth. Method: Suicide attempts in a 15-year prospective study of 180 formerly psychiatrically…

  6. Identifying Children at High Risk for a Child Maltreatment Report

    ERIC Educational Resources Information Center

    Dubowitz, Howard; Kim, Jeongeun; Black, Maureen M.; Weisbart, Cindy; Semiatin, Joshua; Magder, Laurence S.

    2011-01-01

    Objective: To help professionals identify factors that place families at risk for future child maltreatment, to facilitate necessary services and to potentially help prevent abuse and neglect. Method: The data are from a prospective, longitudinal study of 332 low-income families recruited from urban pediatric primary care clinics, followed for…

  7. [Results of the thoracic radiography profile of 247 candidates at the recruiting office of a land-transport society in Abidjan, Cote d'Ivoire].

    PubMed

    N'Goan-Domoua, A M; Konan, A N; Kouame, N; N'Gbesso, R D

    2008-01-01

    The purpose of this prospective study done from May to July 2007 was to show the interest of systematic chest X-Ray of future bus conductors. The main abnormalities were big heart, parenchymal lesion and pleural effusion.

  8. Efficacy Study of a Pre-Algebra Supplemental Program in Rural Mississippi: Preliminary Findings

    ERIC Educational Resources Information Center

    Clark, Tedra F.; Arens, Sheila A.; Stewart, Joshua

    2015-01-01

    Mastering mathematics is important for all students, not only because such success increases college and career options and prospects for future income, but also because mathematics literacy helps citizens and policy leaders to make sound judgments (NMAP, 2008). Research suggests that the rural achievement gap can be addressed with modifiable…

  9. ALOHA System Technical Reports 16, 19, 24, 28, and 30, 1974.

    ERIC Educational Resources Information Center

    Hawaii Univ., Honolulu. ALOHA System.

    A series of technical reports based on the Aloha System for educational computer programs provide a background on how various countries in the Pacific region developed computer capabilities and describe their current operations, as well as prospects for future expansion. Included are studies on the Japan-Hawaii TELEX and Satellite; computers at…

  10. Reflections on the Future Development of Education.

    ERIC Educational Resources Information Center

    United Nations Educational, Scientific, and Cultural Organization, Paris (France).

    Designed to explore the prospects for the development of education throughout the 1980s and 1990s, this study looked at general trends in education in the course of the 1970s, socio-economic evolution in the world, and foreseeable advances in science and technology, in order to outline the priorities for international cooperation. Within the…

  11. Association between telomere length and the risk of colorectal cancer: a meta-analysis of observational studies.

    PubMed

    Naing, Cho; Aung, Kyan; Lai, Pei Kuan; Mak, Joon Wah

    2017-01-05

    Human chromosomes are capped and stabilized by telomeres. Telomere length regulates a 'cellular mitotic clock' that defines the number of cell divisions and hence, cellular life span. This study aimed to synthesize the evidence on the association between peripheral blood leucocytes (PBL) telomere length and the risk of colorectal cancer (CRC). We searched relevant studies in electronic databases. When two or more observational studies reported the same outcome measures, we performed pooled analysis. All the analyses were performed on PBL using PCR. The odds ratio (OR) and its 95% confidence interval (CI) were used to assess the strength of association. Seven studies (with 8 datasets) were included in this meta-analysis; 3 prospective studies, 3 retrospective studies and 1 study with a separate prospective and retrospective designs. The pooled analysis of 4 prospective studies (summary OR 1.01, 95% CI: 0.77-1.34, I 2 :30%) and 4 retrospective studies (summary OR 1.65, 95% CI: 0.96-2.83, I 2 :96%) showed no relationship between PBL telomere length and the CRC risk. A subgroup analysis of 2 prospective studies exclusively on females also showed no association between PBL telomere length and the CRC risk (summary OR, 1.17, 95% CI:0.72-1.91, I 2 :57%). The current analysis is insufficient to provide evidence on the relationship between PBL telomere length and the risk of CRC. Findings suggest that there may be a complex relationship between PBL telomere length and the CRC risk or discrepancy between genetics, age of patients and clinical studies. Future well powered, large prospective studies on the relationship between telomere length and the risk of CRC, and the investigations of the biologic mechanisms are recommended.

  12. The prevention of injuries in contact flag football.

    PubMed

    Kaplan, Yonatan; Myklebust, Grethe; Nyska, Meir; Palmanovich, Ezequiel; Victor, Jan; Witvrouw, Erik

    2014-01-01

    American flag football is a non-tackle, contact sport with many moderate to severe contact-type injuries reported. A previous prospective injury surveillance study by the authors revealed a high incidence of injuries to the fingers, face, knee, shoulder and ankle. The objectives of the study were to conduct a pilot-prospective injury prevention study in an attempt to significantly reduce the incidence and the severity of injuries as compared to a historical cohort, as well as to provide recommendations for a future prospective injury prevention study. A prospective injury prevention study was conducted involving 724 amateur male (mean age: 20.0 ± 3.1 years) and 114 female (mean age: 21.2 ± 7.2 years) players. Four prevention measures were implemented: the no-pocket rule, self-fitting mouth guards, ankle braces (for those players with recurrent ankle sprains) and an injury treatment information brochure. An injury surveillance questionnaire was administered to record all time-loss injuries sustained in game sessions. There was a statistically significant reduction in the number of injured players, the number of finger/hand injuries, the incidence rate and the incidence proportion between the two cohorts (p < 0.05). This one-season pilot prevention study has provided preliminary evidence that finger/hand injuries can be significantly reduced in flag football. Prevention strategies for a longer, prospective, randomised-controlled injury prevention study should include the strict enforcement of the no-pocket rule, appropriate head gear, the use of comfortable-fitting ankle braces and mouth guards, and changing the blocking rules of the game.

  13. Fluorescence detection, enumeration and characterization of single circulating cells in vivo: technology, applications and future prospects

    NASA Astrophysics Data System (ADS)

    Hartmann, Carolin; Patil, Roshani; Lin, Charles P.; Niedre, Mark

    2018-01-01

    There are many diseases and biological processes that involve circulating cells in the bloodstream, such as cancer metastasis, immunology, reproductive medicine, and stem cell therapies. This has driven significant interest in new technologies for the study of circulating cells in small animal research models and clinically. Most currently used methods require drawing and enriching blood samples from the body, but these suffer from a number of limitations. In contrast, ‘in vivo flow cytometry’ (IVFC) refers to set of technologies that allow study of cells directly in the bloodstream of the organism in vivo. In recent years the IVFC field has grown significantly and new techniques have been developed, including fluorescence microscopy, multi-photon, photo-acoustic, and diffuse fluorescence IVFC. In this paper we review recent technical advances in IVFC, with emphasis on instrumentation, contrast mechanisms, and detection sensitivity. We also describe key applications in biomedical research, including cancer research and immunology. Last, we discuss future directions for IVFC, as well as prospects for broader adoption by the biomedical research community and translation to humans clinically.

  14. Fluorescence detection, enumeration and characterization of single circulating cells in vivo: technology, applications and future prospects.

    PubMed

    Hartmann, Carolin; Patil, Roshani; Lin, Charles P; Niedre, Mark

    2017-12-14

    There are many diseases and biological processes that involve circulating cells in the bloodstream, such as cancer metastasis, immunology, reproductive medicine, and stem cell therapies. This has driven significant interest in new technologies for the study of circulating cells in small animal research models and clinically. Most currently used methods require drawing and enriching blood samples from the body, but these suffer from a number of limitations. In contrast, 'in vivo flow cytometry' (IVFC) refers to set of technologies that allow study of cells directly in the bloodstream of the organism in vivo. In recent years the IVFC field has grown significantly and new techniques have been developed, including fluorescence microscopy, multi-photon, photo-acoustic, and diffuse fluorescence IVFC. In this paper we review recent technical advances in IVFC, with emphasis on instrumentation, contrast mechanisms, and detection sensitivity. We also describe key applications in biomedical research, including cancer research and immunology. Last, we discuss future directions for IVFC, as well as prospects for broader adoption by the biomedical research community and translation to humans clinically.

  15. Translating Stem Cell Research to Cardiac Disease Therapies: Pitfalls and Prospects for Improvement

    PubMed Central

    Rosen, Michael R.; Myerburg, Robert J.; Francis, Darrel P.; Cole, Graham D.; Marbán, Eduardo

    2014-01-01

    Over the past 2 decades, there have been numerous stem cell studies focused on cardiac diseases, ranging from proof-of-concept to phase 2 trials. This series of articles focuses on the legacy of these studies and the outlook for future treatment of cardiac diseases with stem cell therapies. The first section by Rosen and Myerburg is an independent review that analyzes the basic science and translational strategies supporting the rapid advance of stem cell technology to the clinic, the philosophies behind them, trial designs, and means for going forward that may impact favorably on progress. The second and third sections were collected in response to the initial section of this review. The commentary by Francis and Cole discusses the Rosen and Myerburg review and details how trial outcomes can be affected by noise, poor trial design (particularly the absence of blinding), and normal human tendencies toward optimism and denial. The final, independent article by Marbán takes a different perspective concerning the potential for positive impact of stem cell research applied to heart disease and future prospects for its clinical application. PMID:25169179

  16. Tolerating Uncertainty: Perceptions of the Future for Ageing Parent Carers and Their Adult Children with Intellectual Disabilities.

    PubMed

    Pryce, Laura; Tweed, Alison; Hilton, Amanda; Priest, Helena M

    2017-01-01

    Improved life expectancy means that more adults with intellectual disabilities are now living with ageing parents. This study explored older families' perceptions of the future. Semi-structured interviews were conducted with nine older parents and three adults with intellectual disabilities and analysed to produce an explanatory thematic framework. 'Tolerating uncertainty' was the major theme in participants' attempts to manage anxieties about the future, encompassing sub-themes of 'accepting the parenting role', 'facing challenges', 'being supported/isolated', 'positive meaning making', 're-evaluating as time moves on' and 'managing future thinking'. Some participants expressed preferences for their future which were in contrast to their parents' views, and provide a unique perspective that has often been neglected in prior research. This research has found commonalities in how families tolerate the uncertainty of the future, but also unique differences that require tailored interventions and prospective action by services. © 2015 John Wiley & Sons Ltd.

  17. The Association between Past and Future Oriented Thinking: Evidence from Autism Spectrum Disorder

    ERIC Educational Resources Information Center

    Lind, Sophie E.; Williams, David M.

    2012-01-01

    A number of recently developed theories (e.g., the constructive episodic simulation, self-projection, and scene construction hypotheses) propose that the ability to simulate possible future events (sometimes referred to as episodic future thinking, prospection, or foresight) depends on the same neurocognitive system that is implicated in the…

  18. Communications and the Future: Prospects, Promises, and Problems.

    ERIC Educational Resources Information Center

    Didsbury, Howard F., Jr., Ed.

    The 45 papers that comprise this book view the current telecommunications revolution and its developments and effects from a wide range of perspectives. Specific topics discussed in the papers include the following: (1) the future of literature; (2) Brazil and the information societies of the next century; (3) the future of language; (4)…

  19. Future riverine nitrogen export to US coastal regions: Prospects for improving water quality considering population growth

    EPA Science Inventory

    Excess nitrogen (N) in the environment degrades ecosystems and adversely affects human health. Here we examine predictions of contemporary (2000) and future (2030) coastal N loading in the continental US by the Nutrient Export from WaterSheds (NEWS) model. Future output is from s...

  20. Mathematics Courses for the Prospective Teacher.

    ERIC Educational Resources Information Center

    Kistler, Barbara C.

    This paper suggests that faculty at two-year institutions need to become partners with colleges of education and K-12 teachers of mathematics in preparing future mathematics teachers. The paper presents the following: a summary of recommendations on programs for prospective teachers; a summary of recommendations about mathematics courses for…

  1. Review and Prospects of Educational Planning and Management in the Arab States.

    ERIC Educational Resources Information Center

    Gennaoui, Antoine M.

    1991-01-01

    Discusses educational planning and administration in the Arab countries during the last decade. Outlines future prospects as they appeared before the Gulf War. Includes structure, practice, mechanisms, and relations between planning structures and administrative authorities. Divides area by geographical contiguity, socio-cultural similarities,…

  2. Research Training--Present & Future.

    ERIC Educational Resources Information Center

    Organisation for Economic Cooperation and Development, Paris (France).

    In 10 papers by independent experts, this volume explores the trends in and prospects for research training in member nations of the Organization for Economic Cooperation and Development. "Problems and Prospects of Research Training in the 1990s" (Stuart Blume) looks at trends in national policy toward research training and issues of…

  3. Multicenter cohort study on association of genotypes with prospective sports concussion: methods, lessons learned, and recommendations.

    PubMed

    Terrell, Thomas R; Bostick, Roberd; Barth, Jeffrey; Sloane, Richard; Cantu, Robert C; Bennett, Ellen; Galloway, Leslie; Laskowitz, Daniel; Erlanger, Dave; McKeag, Doug; Valentine, Verle; Nichols, Gregory

    2017-01-01

    Approximately 3.8 million sports related TBIs occur per year. Genetic variation may affect both TBI risk and post-TBI clinical outcome. Limited research has focused on genetic risk for concussion among athletes. We describe the design, methods, and baseline characteristics of this prospective cohort study designed to investigate a potential association between genetic polymorphisms of apolipoprotein E gene, APOE promoter G-219T, and Tau gene exon 6 polymorphisms (Ser53 Pro and Hist47Tyr) with: 1) the risk of prospective concussion; 2) concussion severity; and 3) postconcussion neurocognitive recovery. The prospective cohort study included a final population of 2947 college, high school, and professional athletes. Baseline data collection included a concussion/medical history questionnaire, neuropsychological (NP) testing, and genetic sampling for the genetic polymorphisms. Data collection on new concussions experienced utilized post-concussion history/mental status form, Lovell post-concussion symptom score, Standardized Assessment of Concussion (SAC) and/or the Sports Concussion Assessment Tool (SCAT)-1/SCAT-2, and post-concussion NP testing. This paper is focused on discussing the important methodological considerations, organizational challenges and lessons learned in the completion of a multi-center prospective cohort study. A total of 3740 subjects enrolled, with a total of 335 concussions experienced. Of critical importance to the success of a study of this type is to successfully recruit committed institutions with qualified local study personnel, obtain "buy-in" from study sites, and cultivate strong working relationships with study sites. The use of approved incentives may improve study site recruitment, enhance retention, and enhance compliance with study protocols. Future publications will detail the specific findings of this study. Collaborative research is very likely needed given the nature of this study population.

  4. Measuring childhood maltreatment to predict early-adult psychopathology: Comparison of prospective informant-reports and retrospective self-reports.

    PubMed

    Newbury, Joanne B; Arseneault, Louise; Moffitt, Terrie E; Caspi, Avshalom; Danese, Andrea; Baldwin, Jessie R; Fisher, Helen L

    2018-01-01

    Both prospective informant-reports and retrospective self-reports may be used to measure childhood maltreatment, though both methods entail potential limitations such as underestimation and memory biases. The validity and utility of standard measures of childhood maltreatment requires clarification in order to inform the design of future studies investigating the mental health consequences of maltreatment. The present study assessed agreement between prospective informant-reports and retrospective self-reports of childhood maltreatment, as well as the comparative utility of both reports for predicting a range of psychiatric problems at age 18. Data were obtained from the Environmental Risk (E-Risk) Longitudinal Twin Study, a nationally-representative birth cohort of 2232 children followed to 18 years of age (with 93% retention). Childhood maltreatment was assessed in two ways: (i) prospective informant-reports from caregivers, researchers, and clinicians when children were aged 5, 7, 10 and 12; and (ii) retrospective self-reports of maltreatment experiences occurring up to age 12, obtained at age 18 using the Childhood Trauma Questionnaire. Participants were privately interviewed at age 18 concerning several psychiatric problems including depression, anxiety, self-injury, alcohol/cannabis dependence, and conduct disorder. There was only slight to fair agreement between prospective and retrospective reports of childhood maltreatment (all Kappa's ≤ 0.31). Both prospective and retrospective reports of maltreatment were associated with age-18 psychiatric problems, though the strongest associations were found when maltreatment was retrospectively self-reported. These findings indicate that prospective and retrospective reports of childhood maltreatment capture largely non-overlapping groups of individuals. Young adults who recall being maltreated have a particularly elevated risk for psychopathology. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  5. Progress and Prospect: A Study of the Kansas City Metropolitan Junior College District; Report to the Board of Trustees.

    ERIC Educational Resources Information Center

    Little (Arthur D.), Inc., Cambridge, MA.

    The Board of Trustees of the Kansas City Metropolitan Junior College District sponsored a long range planning study for the future development of the district. Under the direction of Dr. Raymond J. Young, this study was designed to update an earlier one completed in 1968 by the staff in the light of changed conditions and trends. Information was…

  6. Maternal coping with the prospect of liver transplant among their school-age children.

    PubMed

    Hiratsuka, Katsuhiro; Nakamura, Nobue; Sato, Naho

    2017-06-01

    The purpose of the current study was to describe the following: maternal coping with the prospect of becoming the living-donor liver transplant for their child; the daily lives of school-age children surviving biliary atresia with their native liver; and to explore the relationship between these individuals. Semistructured interviews were conducted with 6 school-age children surviving biliary atresia with their native liver and their mothers. The interviews were conducted from June to August 2014, and a qualitative content analysis was used. Results showed that mothers realized a possible need for transplantation in the future, which contributes to emotional and practical uncertainties. The mothers coexisted with this uncertainty and preferred to use a buffering strategy. In contrast, the children did not consider their illness and future and did not adhere to a therapeutic regimen. It is suggested that living with uncertainty about the health and survival of their children is advantageous for mothers. However, problems related to the psychosocial aspect and child's adherence may occur in the future. In addition, problem-solving coping strategies for mothers and the independence of chronically ill children with liver disease should be promoted. © 2017 John Wiley & Sons Australia, Ltd.

  7. Effects of Obstructive Sleep Apnea and Obesity on Cardiac Remodeling: The Wisconsin Sleep Cohort Study.

    PubMed

    Korcarz, Claudia E; Peppard, Paul E; Young, Terry B; Chapman, Carrie B; Hla, K Mae; Barnet, Jodi H; Hagen, Erika; Stein, James H

    2016-06-01

    To characterize the prospective associations of obstructive sleep apnea (OSA) with future echocardiographic measures of adverse cardiac remodeling. This was a prospective long-term observational study. Participants had overnight polysomnography followed by transthoracic echocardiography a mean (standard deviation) of 18.0 (3.7) y later. OSA was characterized by the apnea-hypopnea index (AHI, events/hour). Echocardiography was used to assess left ventricular (LV) systolic and diastolic function and mass, left atrial volume and pressure, cardiac output, systemic vascular resistance, and right ventricular (RV) systolic function, size, and hemodynamics. Multivariate regression models estimated associations between log10(AHI+1) and future echocardiographic findings. A secondary analysis looked at oxygen desaturation indices and future echocardiographic findings. At entry, the 601 participants were mean (standard deviation) 47 (8) y old (47% female). After adjustment for age, sex, and body mass index, baseline log10(AHI+1) was associated significantly with future reduced LV ejection fraction and tricuspid annular plane systolic excursion (TAPSE) ≤ 15 mm. After further adjustment for cardiovascular risk factors, participants with higher baseline log10(AHI+1) had lower future LV ejection fraction (β = -1.35 [standard error = 0.6]/log10(AHI+1), P = 0.03) and higher odds of TAPSE ≤ 15 mm (odds ratio = 6.3/log10(AHI+1), 95% confidence interval = 1.3-30.5, P = 0.02). SaO2 desaturation indices were associated independently with LV mass, LV wall thickness, and RV area (all P < 0.03). OSA is associated independently with decreasing LV systolic function and with reduced RV function. Echocardiographic measures of adverse cardiac remodeling are strongly associated with OSA but are confounded by obesity. Hypoxia may be a stimulus for hypertrophy in individuals with OSA. © 2016 Associated Professional Sleep Societies, LLC.

  8. The EO-1 autonomous sciencecraft and prospects for future autonomous space exploration

    NASA Technical Reports Server (NTRS)

    Chien, Steve A.

    2005-01-01

    This paper describes the revolutionary new science enabled by onboard autonomy as well as impact on extended missions such as the Mars Exploration Rovers and Mars Odyssey as well as future missions in development.

  9. Nigerian University Libraries: What Future?

    ERIC Educational Resources Information Center

    Aguolu, I. E.

    1996-01-01

    Nigerian university libraries are threatened by underfunding and inadequate collections and facilities. This article examines factors influencing the future prospects of Nigerian university libraries. Discusses Nigeria's mineral oil resources; political instability and stratification of ethnic groups; and the National Universities Commission, the…

  10. New results from RENO & prospects with RENO-50

    NASA Astrophysics Data System (ADS)

    Joo, K. K.

    2017-09-01

    This paper briefly describes recent progress of RENO and next generation future prospect of the reactor neutrino oscillation experiment, RENO-50. Recently the RENO experiment has updated its latest value on sin22θ 13 and provided new results on 5 MeV excess, Δm2 ee, θ 13 with n-H analysis, absolute antineutrino flux measurement, and sterile neutrino search. It gives rich programs of neutrino properties, detector development, nuclear monitoring and application. Using reactor neutrinos, the future RENO-50 experiment will search for more precise measurement of θ 12, Δm 2 12 and mass hierarchy.

  11. [Molecular imaging; current status and future prospects in USA].

    PubMed

    Kobayashi, Hisataka

    2007-02-01

    The goal of this review is to introduce the definition, current status, and future prospects of the molecular imaging, which has recently been a hot topic in medicine and the biological science in USA. In vivo imaging methods to visualize the molecular events and functions in organs or animals/humans are overviewed and discussed especially in combinations of imaging modalities (machines) and contrast agents(chemicals) used in the molecular imaging. Next, the close relationship between the molecular imaging and the nanotechnology, an important part of nanomedicine, is stressed from the aspect of united multidisciplinary sciences such as physics, chemistry, biology, and medicine.

  12. Molecular engineering of industrial enzymes: recent advances and future prospects.

    PubMed

    Yang, Haiquan; Li, Jianghua; Shin, Hyun-Dong; Du, Guocheng; Liu, Long; Chen, Jian

    2014-01-01

    Many enzymes are efficiently produced by microbes. However, the use of natural enzymes as biocatalysts has limitations such as low catalytic efficiency, low activity, and low stability, especially under industrial conditions. Many protein engineering technologies have been developed to modify natural enzymes and eliminate these limitations. Commonly used protein engineering strategies include directed evolution, site-directed mutagenesis, truncation, and terminal fusion. This review summarizes recent advances in the molecular engineering of industrial enzymes and discusses future prospects in this field. We expect this review to increase interest in and advance the molecular engineering of industrial enzymes.

  13. Eating disorders: Insights from imaging and behavioral approaches to treatment.

    PubMed

    Stice, Eric; Shaw, Heather

    2017-11-01

    Understanding factors that contribute to eating disorders, which affect 13% of females, is critical to developing effective prevention and treatment programs. In this paper, we summarize results from prospective studies that identified factors predicting onset and persistence of eating disorders and core symptom dimensions. Next, implications for intervention targets for prevention, and treatment interventions from the risk- and maintenance-factor findings are discussed. Third, given that evidence suggests eating disorders are highly heritable, implying biological risk and maintenance factors for eating disorders, we offer working hypotheses about biological factors that might contribute to eating disorders, based on extant risk factor findings, theory, and cross-sectional studies. Finally, potentially fruitful directions for future research are presented. We suggest that it would be useful for experimental therapeutics trials to evaluate the effects of reducing the risk factors on future onset of eating pathology and on reducing maintenance factors on the risk for persistence of eating pathology, and encourage researchers to utilize prospective high-risk studies so that knowledge regarding potential intervention targets for prevention and treatment interventions for eating disorders can be advanced. Using the most rigorous research designs should help improve the efficacy of prevention and treatment interventions for eating disorders.

  14. Does Problem Behavior Elicit Poor Parenting?: A Prospective Study of Adolescent Girls

    PubMed Central

    Huh, David; Tristan, Jennifer; Wade, Emily; Stice, Eric

    2006-01-01

    This study tested the hypothesis that perceived parenting would show reciprocal relations with adolescents' problem behavior using longitudinal data from 496 adolescent girls. Results provided support for the assertion that female problem behavior has an adverse effect on parenting; elevated externalizing symptoms and substance abuse symptoms predicted future decreases in perceived parental support and control. There was less support for the assertion that parenting deficits foster adolescent problem behaviors; initially low parental control predicted future increases in substance abuse, but not externalizing symptoms, and low parental support did not predict future increases in externalizing or substance abuse symptoms. Results suggest that problem behavior is a more consistent predictor of parenting than parenting is of problem behavior, at least for girls during middle adolescence. PMID:16528407

  15. Alcohol-induced blackouts, subjective intoxication, and motivation to decrease drinking: Prospective examination of the transition out of college.

    PubMed

    Marino, Elise N; Fromme, Kim

    2018-05-01

    We prospectively examined whether subjective intoxication serves as a risk factor for experiencing alcohol-induced blackouts. We then examined whether subjective intoxication and/or blackouts predicted motivation to decrease their drinking, and whether this motivation to change would promote future changes in drinking behavior. Participants (N=1854, 62.1% female, 53.2% Caucasian, M age =21.8) were recruited the summer prior to matriculating into a large, public university to complete a 6-year longitudinal study. Self-reported motivation to decrease their drinking behavior, their frequency of blackouts, quantity of alcohol consumption, and subjective intoxication (i.e., feeling drunk) were assessed annually during the transition out of college (Years 4-6). In a cross-lagged model, subjective intoxication (i.e., feeling drunk) prospectively predicted experiencing blackouts (p<0.001). Controlling for both objective (e.g., quantity) and subjective intoxication, blackouts at Year 4 predicted greater motivation to decrease drinking behavior at Year 5 (p<0.01), but this motivation did not predict less quantity of alcohol use by Year 6 (p=0.076). Subjective intoxication is a robust predictor of blackouts across time. Additionally, blackouts are modest, developmentally-limited predictors of motivation to change drinking behavior, but blackouts do not predict future behavior change. Copyright © 2018 Elsevier Ltd. All rights reserved.

  16. A Retrospective Analysis of the Benefits and Impacts of U.S. Renewable Portfolio Standards

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wiser, Ryan; Barbose, Galen; Heeter, Jenny

    This is the second in a series of reports exploring the costs, benefits, and other impacts of state renewable portfolio standards (RPS), both retrospectively and prospectively. This report focuses on the benefits and impacts of all state RPS programs, in aggregate, for the year 2013 (the most-recent year for which the requisite data were available). Relying on a well-vetted set of methods, the study evaluates a number of important benefits and impacts in both physical and monetary terms, where possible, and characterizes key uncertainties. The prior study in this series focused on historical RPS compliance costs, and future work willmore » evaluate costs, benefits, and other impacts of RPS policies prospectively.« less

  17. At the precipice: a prospective exploration of medical students' expectations of the pre-clerkship to clerkship transition.

    PubMed

    Soo, Jason; Brett-MacLean, Pamela; Cave, Marie-Therese; Oswald, Anna

    2016-03-01

    Medical learners face many challenging transitions. We prospectively explored students' perceptions of their upcoming transition to clerkship and their future professional selves. In 2013, 160/165 end-of-second-year medical students wrote narrative reflections and 79/165 completed a questionnaire on their perceptions of their upcoming transition to clerkship. Narratives were separately analyzed by four authors and then discussed to identify a final thematic framework using parsimonious category construction. We identified two overarching themes: (1) "Looking back": experiences which had helped students feel prepared for clerkship with subthemes focused on of patient care, shadowing, classroom teaching and the pre-clerkship years as foundational knowledge, (2) "Looking forward": anticipating the clerkship experience and the journey of becoming a physician with subthemes focused on death and dying, hierarchy, work-life balance, interactions with patients, concerns about competency and career choice. Questionnaire data revealed incongruities around expectations of minimal exposure to death and dying, little need for independent study and limited direct patient responsibility. We confirmed that internal transformations are happening in contemplative time even before clerkship. By prospectively exploring pre-clerkship students' perceptions of the transition to clerkship training we identified expectations and misconceptions that could be addressed with future curricular interventions. While students are aware of and anticipating their learning needs it is not as clear that they realise how much their future learning will depend on their own inner resources. We suggest that more attention be paid to professional identity formation and the development of the physician as a person during these critical transitions.

  18. Database documentation of marine mammal stranding and mortality: current status review and future prospects.

    PubMed

    Chan, Derek K P; Tsui, Henry C L; Kot, Brian C W

    2017-11-21

    Databases are systematic tools to archive and manage information related to marine mammal stranding and mortality events. Stranding response networks, governmental authorities and non-governmental organizations have established regional or national stranding networks and have developed unique standard stranding response and necropsy protocols to document and track stranded marine mammal demographics, signalment and health data. The objectives of this study were to (1) describe and review the current status of marine mammal stranding and mortality databases worldwide, including the year established, types of database and their goals; and (2) summarize the geographic range included in the database, the number of cases recorded, accessibility, filter and display methods. Peer-reviewed literature was searched, focussing on published databases of live and dead marine mammal strandings and mortality and information released from stranding response organizations (i.e. online updates, journal articles and annual stranding reports). Databases that were not published in the primary literature or recognized by government agencies were excluded. Based on these criteria, 10 marine mammal stranding and mortality databases were identified, and strandings and necropsy data found in these databases were evaluated. We discuss the results, limitations and future prospects of database development. Future prospects include the development and application of virtopsy, a new necropsy investigation tool. A centralized web-accessed database of all available postmortem multimedia from stranded marine mammals may eventually support marine conservation and policy decisions, which will allow the use of marine animals as sentinels of ecosystem health, working towards a 'One Ocean-One Health' ideal.

  19. Aptamer-siRNA Chimeras: Discovery, Progress, and Future Prospects

    PubMed Central

    Kruspe, Sven; Giangrande, Paloma H.

    2017-01-01

    Synthetic nucleic acid ligands (aptamers) have emerged as effective delivery tools for many therapeutic oligonucleotide-based drugs, including small interfering RNAs (siRNAs). In this review, we summarize recent progress in the aptamer selection technology that has made possible the identification of cell-specific, cell-internalizing aptamers for the cell-targeted delivery of therapeutic oligonucleotides. In addition, we review the original, proof-of-concept aptamer-siRNA delivery studies and discuss recent advances in aptamer-siRNA conjugate designs for applications ranging from cancer therapy to the development of targeted antivirals. Challenges and prospects of aptamer-targeted siRNA drugs for clinical development are further highlighted. PMID:28792479

  20. Summary and Prospect.

    PubMed

    Wei, Zhengde; Chen, Xueli; Zhang, Xiaochu

    2017-01-01

    In this chapter, the main content is to summarize the similarities and differences between substance and non-substance addictions in several aspects, involving definition, mechanisms, diagnosis and treatment. We try to display the complete picture of addictions in a brief but comprehensive way. Mechanism includes molecule and neural circuit, genetics, neuroimaging and cognitive psychology; diagnosis includes diagnostic criterion, diagnostic scales, biochemical diagnosis and new diagnostic techniques; treatment includes drug therapy, physical therapy, traditional Chinese medical therapy, nutrition support therapy, psychotherapy and cognitive-behavioral therapy. This chapter also covers some prospect which will induct future studies on addiction. We aim at providing the researchers and graduate students with better understanding of substance and non-substance addictions.

  1. Future prospects in dermatologic applications of lasers, nanotechnology, and other new technologies.

    PubMed

    Boixeda, P; Feltes, F; Santiago, J L; Paoli, J

    2015-04-01

    We review novel technologies with diagnostic and therapeutic applications in dermatology. Among the diagnostic techniques that promise to become part of dermatologic practice in the future are optical coherence tomography, multiphoton laser scanning microscopy, Raman spectroscopy, thermography, and 7-T magnetic resonance imaging. Advances in therapy include novel light-based treatments, such as those applying lasers to new targets and in new wavelengths. Devices for home therapy are also appearing. We comment on the therapeutic uses of plasma, ultrasound, radiofrequency energy, total reflection amplification of spontaneous emission of radiation, light stimulation, and transepidermal drug delivery. Finally, we mention some basic developments in nanotechnology with prospects for future application in dermatology. Copyright © 2014 Elsevier España, S.L.U. and AEDV. All rights reserved.

  2. Investigating and analyzing prospective teacher's reflective thinking in solving mathematical problem: A case study of female-field dependent (FD) prospective teacher

    NASA Astrophysics Data System (ADS)

    Agustan, S.; Juniati, Dwi; Siswono, Tatag Yuli Eko

    2017-05-01

    In the last few years, reflective thinking becomes very popular term in the world of education, especially in professional education of teachers. One of goals of the educational personnel and teacher institutions create responsible prospective teachers and they are able reflective thinking. Reflective thinking is a future competence that should be taught to students to face the challenges and to respond of demands of the 21st century. Reflective thinking can be applied in mathematics becauseby reflective thinking, students can improve theircuriosity to solve mathematical problem. In solving mathematical problem is assumed that cognitive style has an impact on prospective teacher's mental activity. As a consequence, reflective thinking and cognitive style are important things in solving mathematical problem. The subject, in this research paper, isa female-prospective teacher who has fielddependent cognitive style. The purpose of this research paperis to investigate the ability of prospective teachers' reflective thinking in solving mathematical problem. This research paper is a descriptive by using qualitativeapproach. To analyze the data related to prospectiveteacher's reflective thinking in solving contextual mathematicalproblem, the researchers focus in four main categories which describe prospective teacher's activities in using reflective thinking, namely; (a) formulation and synthesis of experience, (b) orderliness of experience, (c) evaluating the experience and (d) testing the selected solution based on the experience.

  3. Exclusive muon neutrino charged current pion-less topologies. ArgoNeuT results and future prospects in LAr TPC detectors

    DOE PAGES

    Palamara, Ornella

    2016-12-29

    Results from the analysis of charged current pion-less (CC 0-pion) muon neutrino events in argon collected by the ArgoNeuT experiment on the NuMI beam at Fermilab are presented and compared with predictions from Monte Carlo simulations. A novel analysis method, based on the reconstruction of exclusive topologies, fully exploiting the Liquid argon Time Projection Chamber (LAr TPC) technique capabilities, is used to analyze the events, characterized by the presence at the vertex of a leading muon track eventually accompanied by one or more highly ionizing tracks, and study nuclear effects in neutrino interactions on argon nuclei. Multiple protons accompanying themore » leading muon are visible in the ArgoNeuT events, and measured with a proton reconstruction threshold of 21 MeV kinetic energy. As a result, measurements of (anti-)neutrino CC 0-pion inclusive and exclusive cross sections on argon nuclei are reported. Prospects for future, larger mass LAr TPC detectors are discussed.« less

  4. The delay period as an opportunity to think about future intentions: Effects of delay length and delay task difficulty on young adult's prospective memory performance.

    PubMed

    Mahy, Caitlin E V; Schnitzspahn, Katharina; Hering, Alexandra; Pagobo, Jacqueline; Kliegel, Matthias

    2018-05-01

    The current study examined the impact of length and difficulty of the delay task on young adult's event-based prospective memory (PM). Participants engaged in either a short (2.5 min) or a long (15 min) delay that was filled with either a simple item categorization task or a difficult cognitive task. They also completed a questionnaire on whether they thought about the PM intention during the delay period and how often they thought about it. Results revealed that participants' PM was better after a difficult delay task compared to an easy delay task. Participants thought about the PM intention more often during the difficult delay task than during the easy delay task. PM performance was positively related to participants' reports of how many times they thought about their intentions. The important role of delay task difficulty in allowing or preventing individuals from refreshing their future intentions is discussed.

  5. Self-projection in younger and older adults: a study of episodic memory, prospection, and theory of mind.

    PubMed

    Jarvis, Shoshana N; Miller, Jeremy K

    2017-07-01

    Self-projection is the ability to orient the self in different places in time and space. Episodic memory, prospection, and theory of mind (ToM) are all cognitive abilities that share an element of self-projection. Previous research has posited that each of these abilities stems from the same neural network. The current study compared performance of cognitively healthy older adults and younger adults on several self-projection tasks to examine the relatedness of these constructs behaviorally. Episodic memory and prospection were measured using an episodic interview task where the participants were asked to remember or imagine events that either had happened in the past or could happen in the future and then gave ratings describing the extent to which they were mentally experiencing the event and from what perspective they viewed it. ToM was measured by asking participants to make judgments regarding the intentions of characters described in stories that involved cognitive, affective, or ironic components. Our results demonstrate that aging influences episodic memory, prospection, and ToM similarly: older adult participants showed declines on each of these measures compared to younger adults. Further, we observed correlations between performance on the measures of episodic memory and prospection as well as between episodic memory and ToM, although no correlation between prospection and ToM was observed after controlling for chronological age. We discuss these results in the light of theories suggesting that each of these abilities is governed by a common brain system.

  6. Orientation towards the Future by Liberian Schoolchildren. A Contribution to the Understanding of Young West Africans.

    ERIC Educational Resources Information Center

    Fricke, R.

    1979-01-01

    African children's time perspective and orientation towards the future were analyzed in compositions entitled "Future Prospects in my Life," written by 754 boys and 306 girls in 11 schools, grades 5-12, in Liberia, West Africa. Content analysis indicated that both sexes were most interested in "education and profession" and…

  7. The University of the Future: Problems and Prospects.

    ERIC Educational Resources Information Center

    Bjornson, Richard, Ed.; Waldman, Marilyn R., Ed.

    Most of the 15 papers presented here were originally presented at a May, 1987 colloquium held in Columbus, Ohio, on "The Educated Citizen and the University of the Future." Papers and their authors are as follows: "Thinking About the University of the Future" (Richard Bjornson and Marilyn R. Waldman); "The Old and the New: The University of Today…

  8. Computational Fluid Dynamics: Past, Present, And Future

    NASA Technical Reports Server (NTRS)

    Kutler, Paul

    1988-01-01

    Paper reviews development of computational fluid dynamics and explores future prospects of technology. Report covers such topics as computer technology, turbulence, development of solution methodology, developemnt of algorithms, definition of flow geometries, generation of computational grids, and pre- and post-data processing.

  9. Training Preschoolers' Prospective Abilities through Conversation about the Extended Self

    ERIC Educational Resources Information Center

    Chernyak, Nadia; Leech, Kathryn A.; Rowe, Meredith L.

    2017-01-01

    The ability to act on behalf of one's future self is related to uniquely human abilities such as planning, delay of gratification, and goal attainment. Although prospection develops rapidly during early childhood, little is known about the mechanisms that support its development. Here we explored whether encouraging children to talk about their…

  10. Prospective Teachers' Opinions Concerning Children's Rights

    ERIC Educational Resources Information Center

    Faiz, Melike; Kamer, Selman Tunay

    2017-01-01

    Consideration of the child as a social being and his/her not having the power of self-protection have propounded the significance of children's rights. Teachers are important to educate the individual. Prospective teachers who will be teachers of the future will have a considerable amount of presidency. Thus, the main objective of this research is…

  11. Effect of emotional cues on prospective memory performance in patients with schizophrenia and major depressive disorder.

    PubMed

    Yang, Tian-Xiao; Cui, Xi-Long; Wang, Ya; Huang, Jing; Lui, Simon S Y; Zhang, Rui-Ting; Cheung, Eric F C; Chan, Raymond C K

    2018-05-24

    Prospective memory (PM) is the ability to remember to carry out future intentions when prompted by a cue, and previous studies have suggested that emotional PM cues may enhance PM performance. This study examined the influence of emotional cues on PM performance in patients with schizophrenia and major depressive disorder. All participants were required to respond to emotional or neutral PM cues while completing a working memory task. Healthy participants showed improved PM performance with positive and negative cues. Patients with major depressive disorder were not impaired in PM performance and showed significant improvement in PM performance when cued by negative but not positive cues. Patients with schizophrenia had impaired PM performance irrespective of cue emotionality. In addition, the majority of patients with schizophrenia failed to show an emotional enhancement effect, and only those who had normal arousal ratings for negative PM cues showed emotional enhancement effect. These findings show for the first time that patients with schizophrenia exhibit PM impairments even with emotional cues, and suggest that arousal may be a critical factor for schizophrenia patients to utilize emotional cues to facilitate execution of future actions. In patients with major depressive disorder, our findings suggest that the negative bias in attention and retrospective memory may also extend to memory for future actions. These novel findings have both theoretical and clinical implications. Copyright © 2018. Published by Elsevier B.V.

  12. Predicting Noninsulin Antidiabetic Drug Adherence Using a Theoretical Framework Based on the Theory of Planned Behavior in Adults With Type 2 Diabetes

    PubMed Central

    Zomahoun, Hervé Tchala Vignon; Moisan, Jocelyne; Lauzier, Sophie; Guillaumie, Laurence; Grégoire, Jean-Pierre; Guénette, Line

    2016-01-01

    Abstract Understanding the process behind noninsulin antidiabetic drug (NIAD) nonadherence is necessary for designing effective interventions to resolve this problem. This study aimed to explore the ability of the theory of planned behavior (TPB), which is known as a good predictor of behaviors, to predict the future NIAD adherence in adults with type 2 diabetes. We conducted a prospective study of adults with type 2 diabetes. They completed a questionnaire on TPB variables and external variables. Linear regression was used to explore the TPB's ability to predict future NIAD adherence, which was prospectively measured as the proportion of days covered by at least 1 NIAD using pharmacy claims data. The interaction between past NIAD adherence and intention was tested. The sample included 340 people. There was an interaction between past NIAD adherence and intention to adhere to the NIAD (P = 0.032). Intention did not predict future NIAD adherence in the past adherers and nonadherers groups, but its association measure was high among past nonadherers (β = 5.686, 95% confidence interval [CI] −10.174, 21.546). In contrast, intention was mainly predicted by perceived behavioral control both in the past adherers (β = 0.900, 95% CI 0.796, 1.004) and nonadherers groups (β = 0.760, 95% CI 0.555, 0.966). The present study suggests that TPB is a good tool to predict intention to adhere and future NIAD adherence. However, there was a gap between intention to adhere and actual adherence to the NIAD, which is partly explained by the past adherence level in adults with type 2 diabetes. PMID:27082543

  13. The Value of Serum CA125 in the Diagnosis of Borderline Tumors of the Ovary: A Subanalysis of the Prospective Multicenter ROBOT Study.

    PubMed

    Fotopoulou, Christina; Sehouli, Jalid; Ewald-Riegler, Nina; de Gregorio, Nikolaus; Reuss, Alexander; Richter, Rolf; Mahner, Sven; Kommoss, Friedrich; Schmalfeldt, Barbara; Fehm, Tanja; Hanker, Lars; Wimberger, Pauline; Canzler, Ulrich; Pfisterer, Jacobus; Kommoss, Stefan; Hauptmann, Steffen; du Bois, Andreas

    2015-09-01

    The value of the serum tumor marker CA125 in borderline tumors of the ovary (BOTs) is not well defined, with unclear benefit in both diagnosis and follow-up. The aim of the present project was to identify the predictive value of CA125 for stage and relapse. CA125 data were extracted from the ROBOT multicenter study of patients with BOT treated between 1998 and 2008 in 24 German centers. While patients' data were retrieved retrospectively from hospital records and clinical tumor registries, follow-up and independent central pathology review were performed prospectively. We identified 127 patients from the ROBOT database fulfilling the eligibility criterion of available CA125 at initial diagnosis. Eighty-three (65.3%) patients had increased CA125 levels (>35 U/L). Of the patients, 85.0% presented with serous and 13.4% with mucinous BOT histology, whereas 29.9% had stage I disease. Fifteen (11.8%) patients experienced a relapse. Multivariate analysis identified raised CA125, young age, and serous histology as independent predictors of peritoneal implants of any type at initial presentation. Raised CA125 at initial diagnosis was, however, not an independent predictor of future relapse. Elevated CA125 seems to be associated with the presence of peritoneal implants of any type at initial diagnosis of serous BOT, but failed to have any independent predictive value on future relapse. Prospective multicenter studies are warranted to evaluate CA125 measurements in the follow-up management of BOT.

  14. Keeping on Track: Performance Profiles of Low Performers in Academic Educational Tracks

    ERIC Educational Resources Information Center

    Reed, Helen C.; van Wesel, Floryt; Ouwehand, Carolijn; Jolles, Jelle

    2015-01-01

    In countries with high differentiation between academic and vocational education, an individual's future prospects are strongly determined by the educational track to which he or she is assigned. This large-scale, cross-sectional study focuses on low-performing students in academic tracks who face being moved to a vocational track. If more is…

  15. Status and future prospects of using numerical methods to study complex flows at High Reynolds numbers

    NASA Technical Reports Server (NTRS)

    Maccormack, R. W.

    1978-01-01

    The calculation of flow fields past aircraft configuration at flight Reynolds numbers is considered. Progress in devising accurate and efficient numerical methods, in understanding and modeling the physics of turbulence, and in developing reliable and powerful computer hardware is discussed. Emphasis is placed on efficient solutions to the Navier-Stokes equations.

  16. Accreditation in the USA: Origins, Developments and Future Prospects. Improving the Managerial Effectiveness of Higher Education.

    ERIC Educational Resources Information Center

    El-Khawas, Elaine

    This study analyzes the accreditation experience in the United States with special emphasis on the issues and decisions that surrounded the development of evaluation procedures and standards. Attention is given to the relationship between accrediting agencies and governmental agencies, the effect of accrediting requirements on the way that…

  17. Enlargement Project: Insight into ICT Professional Skills and Jobs in the Candidate Countries. Enlargement Futures Series.

    ERIC Educational Resources Information Center

    Gourova, Elissaveta

    A study examined information and communication technologies (ICT) job trends and the prospects for preservation and supply of high skilled professionals in the medium and longer term in candidate countries (CCs), for admission into the European Union, focusing on Bulgaria, Estonia, Hungary, and Poland. Rapidly changing technology and growth of…

  18. Does Higher Education Curriculum Contribute to Prospective Teachers' Attitudes, Self-Efficacy and Motivation?

    ERIC Educational Resources Information Center

    Koludrovic, Morana; Ercegovac, Ina Reic

    2017-01-01

    In Croatia, another comprehensive reform of the education system is being implemented. Although it proposes a number of reforms to the school system, we think that providing better training to future teachers during their studies would further contribute to the quality of education. The initial education of elementary and high school teachers is…

  19. Independent Education in Western Europe, Second Edition. ISIS Document No. 34.

    ERIC Educational Resources Information Center

    Mason, Peter

    In 1992, a study described the legal status, aims, organization, resources, role, and future prospects of the independent educational sector of the 17 countries of Western Europe and the context in which that sector operated. In the six years since the compilation, the European Economic Community has become the European Union. It has increased its…

  20. State Arts Policy: Trends and Future Prospects

    ERIC Educational Resources Information Center

    Lowell, Julia F.

    2008-01-01

    State arts agencies (SAAs)--key players within the U.S. system of public support for the arts--face growing economic, political, and demographic challenges to the roles and missions they adopted when founded in the mid-1960s. This report, the fourth and final in a multiyear study, looks at state arts agencies' efforts to rethink their roles and…

  1. Current State and Future Prospects of Education for Sustainable Development (ESD) in Japan

    ERIC Educational Resources Information Center

    Tanaka, Haruhiko

    2017-01-01

    The UN Decade of Education for Sustainable Development (ESD) ran from 2005 to 2014. This study concerns the concepts of Sustainable Development (SD) and ESD. The term "sustainable development" was coined by the Brundtland Commission in 1987 as the key word in integrating environment and development. SD achieved international consensus at…

  2. Psychosocial Stress Predicts Future Symptom Severities in Children and Adolescents with Tourette Syndrome and/or Obsessive-Compulsive Disorder

    ERIC Educational Resources Information Center

    Lin, Haiqun; Katsovich, Liliya; Ghebremichael, Musie; Findley, Diane B.; Grantz, Heidi; Lombroso, Paul J.; King, Robert A.; Zhang, Heping; Leckman, James F.

    2007-01-01

    Background: The goals of this prospective longitudinal study were to monitor levels of psychosocial stress in children and adolescents with Tourette syndrome (TS) and/or obsessive-compulsive disorder (OCD) compared to healthy control subjects and to examine the relationship between measures of psychosocial stress and fluctuations in tic,…

  3. Prospective Elementary Teachers' Views on Their Teachers and Their Effectiveness

    ERIC Educational Resources Information Center

    Karakas, Mehmet

    2013-01-01

    In this paper future elementary teachers reflect on their past experiences and talk about their teachers and the way they were taught, and portray the characteristics of effective and not so effective teachers. The study also highlights Turkish teachers` way of instruction and the strategies they use. Participants were 41 sophomore and 62 junior…

  4. Data storage: Retrospective and prospective

    NASA Technical Reports Server (NTRS)

    Speliotis, Dennis E.

    1993-01-01

    We study history to learn from its lessons so we don't repeat the mistakes. Ironically, however, sometimes it seems that the lessons we learn from history is how to repeat the mistakes more precisely. A brief discussion about the history of magnetic recording is presented, and the lessons of the past are used to look into the future.

  5. Ending on a High Note: Adding a Better End to Effortful Study

    ERIC Educational Resources Information Center

    Finn, Bridgid

    2010-01-01

    Remembered utility is the retrospective evaluation about the pleasure and pain associated with a past experience. It has been shown to influence prospective choices about whether to repeat or to avoid similar situations in the future (D. Kahneman 2000; D. Kahneman, D. L. Fredrickson, C. A. Schreiber, & D. A. Redelmeier, 1993). Evaluations…

  6. Children’s mental time travel during mind wandering

    PubMed Central

    Ye, Qun; Song, Xiaolan; Zhang, Yi; Wang, Qinqin

    2014-01-01

    The prospective bias is a salient feature of mind wandering in healthy adults, yet little is known about the temporal focus of children’s mind wandering. In the present study, (I) we developed the temporal focus of mind wandering questionnaire for school-age children (TFMWQ-C), a 12-item scale with good test–retest reliability and construct validity. (II) The criterion validity was tested by thought sampling in both choice reaction time task and working memory task. A positive correlation was found between the temporal focus measured by the questionnaire and the one adopted during task-unrelated thoughts (TUTs) by thought sampling probes, especially in the trait level of future-oriented mind wandering. At the same time, children who experienced more TUTs tended to show worse behavioral performance during tasks. (III) The children in both tasks experienced more future-oriented TUTs than past-oriented ones, which was congruent with the results observed in adults; however, in contrast with previous research on adults, the prospective bias was not influenced by task demands. Together these results indicate that the prospective bias of mind wandering has emerged since the school-age (9∼13 years old), and that the relationship between mental time travel (MTT) during mind wandering and the use of cognitive resources differs between children and adults. Our study provides new insights into how this interesting feature of mind wandering may adaptively contribute to the development of children’s MTT. PMID:25191301

  7. The value of foresight: how prospection affects decision-making.

    PubMed

    Pezzulo, Giovanni; Rigoli, Francesco

    2011-01-01

    Traditional theories of decision-making assume that utilities are based on the intrinsic value of outcomes; in turn, these values depend on associations between expected outcomes and the current motivational state of the decision-maker. This view disregards the fact that humans (and possibly other animals) have prospection abilities, which permit anticipating future mental processes and motivational and emotional states. For instance, we can evaluate future outcomes in light of the motivational state we expect to have when the outcome is collected, not (only) when we make a decision. Consequently, we can plan for the future and choose to store food to be consumed when we expect to be hungry, not immediately. Furthermore, similarly to any expected outcome, we can assign a value to our anticipated mental processes and emotions. It has been reported that (in some circumstances) human subjects prefer to receive an unavoidable punishment immediately, probably because they are anticipating the dread associated with the time spent waiting for the punishment. This article offers a formal framework to guide neuroeconomic research on how prospection affects decision-making. The model has two characteristics. First, it uses model-based Bayesian inference to describe anticipation of cognitive and motivational processes. Second, the utility-maximization process considers these anticipations in two ways: to evaluate outcomes (e.g., the pleasure of eating a pie is evaluated differently at the beginning of a dinner, when one is hungry, and at the end of the dinner, when one is satiated), and as outcomes having a value themselves (e.g., the case of dread as a cost of waiting for punishment). By explicitly accounting for the relationship between prospection and value, our model provides a framework to reconcile the utility-maximization approach with psychological phenomena such as planning for the future and dread.

  8. The Value of Foresight: How Prospection Affects Decision-Making

    PubMed Central

    Pezzulo, Giovanni; Rigoli, Francesco

    2011-01-01

    Traditional theories of decision-making assume that utilities are based on the intrinsic value of outcomes; in turn, these values depend on associations between expected outcomes and the current motivational state of the decision-maker. This view disregards the fact that humans (and possibly other animals) have prospection abilities, which permit anticipating future mental processes and motivational and emotional states. For instance, we can evaluate future outcomes in light of the motivational state we expect to have when the outcome is collected, not (only) when we make a decision. Consequently, we can plan for the future and choose to store food to be consumed when we expect to be hungry, not immediately. Furthermore, similarly to any expected outcome, we can assign a value to our anticipated mental processes and emotions. It has been reported that (in some circumstances) human subjects prefer to receive an unavoidable punishment immediately, probably because they are anticipating the dread associated with the time spent waiting for the punishment. This article offers a formal framework to guide neuroeconomic research on how prospection affects decision-making. The model has two characteristics. First, it uses model-based Bayesian inference to describe anticipation of cognitive and motivational processes. Second, the utility-maximization process considers these anticipations in two ways: to evaluate outcomes (e.g., the pleasure of eating a pie is evaluated differently at the beginning of a dinner, when one is hungry, and at the end of the dinner, when one is satiated), and as outcomes having a value themselves (e.g., the case of dread as a cost of waiting for punishment). By explicitly accounting for the relationship between prospection and value, our model provides a framework to reconcile the utility-maximization approach with psychological phenomena such as planning for the future and dread. PMID:21747755

  9. Current Situation and Future Prospects for Global Beef Production: Overview of Special Issue.

    PubMed

    Smith, Stephen B; Gotoh, Takafumi; Greenwood, Paul L

    2018-05-31

    The demand for beef as a protein source is increasing worldwide, although in most countries beef accounts for considerably less than half of total meat consumption. Beef also provides a highly desirable eating experience in developed countries and, increasingly, in developing countries. The sustainability of beef production has different meanings in the various geographical and socio-economic regions of the world. Natural resources including land mass and uses, rainfall and access to livestock feed, and the robustness of the economy are major determinants of the perception of beef sustainability. In this overview of the 2016 International Symposium on "Future Beef in Asia" and this subsequent Special Edition of the Asian-Australasian Journal of Animal Sciences on "Current Situation and Future Prospects for Global Beef Production", the contributions have been grouped into the following categories: Countries in Southeast Asia; Europe; and Countries producing highly marbled beef for export and/or domestic consumption. They also include reference to Special Topics including marbled beef production, and use of "omics" technologies to enhance beef quality assurance. Among these broad categories, notable differences exist across countries in the production and marketing of beef. These reflect differences in factors including natural resource availability and climate, population size, traditional culture and degree of economic development including industrial and technological developments. We trust that the International Symposium and this Special Edition on Current Situation and Future Prospects for Global Beef Production, the contents of which that are briefly summarized in this paper, will serve as a valuable resource for the livestock industries, researchers and students with an interest in enhancing the prospects for sustainable, efficient beef production that satisfies the growing size and complexity of consumer demands and markets for beef.

  10. Environmental analysis of geopressured-geothermal prospect areas, De Witt and Colorado counties, Texas. Final report, March 1 - August 31, 1979

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gustavson, T.C.; Reeder, F.S.; Badger, E.A.

    Information collected and analyzed for a preliminary environmental analysis of geopressured geothermal prospect areas in Colorado and DeWitt Counties, Texas is presented. Specific environmental concerns for each geopressured geothermal prospect area are identified and discussed. Approximately 218 km/sup 2/(85 mi/sup 2/) were studied in the vicinity of each prospect area to: (1) conduct an environmental analysis to identify more and less suited areas for geopressured test wells; and (2) provide an environmental data base for future development of geopressured geothermal energy resources. A series of maps and tables are included to illustrate environmental characteristics including: geology, water resources, soils, currentmore » land use, vegetation, wildlife, and meteorological characteristics, and additional relevant information on cultural resources, power- and pipelines, and regulatory agencies. A series of transparent overlays at the scale of the original mapping has also been produced for the purposes of identifying and ranking areas of potential conflict between geopressured geothermal development and environmental characteristics. The methodology for ranking suitability of areas within the two prospect areas is discussed in the appendix. (MHR)« less

  11. Does Goal Relevant Episodic Future Thinking Amplify the Effect on Delay Discounting?

    PubMed Central

    O’Donnell, Sara; Daniel, Tinuke Oluyomi; Epstein, Leonard H.

    2017-01-01

    Delay discounting (DD) is the preference for smaller immediate rewards over larger delayed rewards. Research shows episodic future thinking (EFT), or mentally simulating future experiences, reframes the choice between small immediate and larger delayed rewards, and can reduce DD. Only general EFT has been studied, whereby people reframe decisions in terms of non-goal related future events. Since future thinking is often goal-oriented and leads to greater activation of brain regions involved in prospection, goal-oriented EFT may be associated with greater reductions in DD than general goal-unrelated EFT. The present study (n = 104, Mage = 22.25, SD = 3.42; 50% Female) used a between-subjects 2×2 factorial design with type of episodic thinking (Goal, General) and temporal perspective (Episodic future versus recent thinking; EFT vs ERT) as between factors. Results showed a significant reduction in DD for EFT groups (p < 0.001, Cohen’s d effect size = 0.89), and goal-EFT was more effective than general-EFT on reducing DD (p = 0.03, d = 0.64). PMID:28282631

  12. Does goal relevant episodic future thinking amplify the effect on delay discounting?

    PubMed

    O'Donnell, Sara; Oluyomi Daniel, Tinuke; Epstein, Leonard H

    2017-05-01

    Delay discounting (DD) is the preference for smaller immediate rewards over larger delayed rewards. Research shows episodic future thinking (EFT), or mentally simulating future experiences, reframes the choice between small immediate and larger delayed rewards, and can reduce DD. Only general EFT has been studied, whereby people reframe decisions in terms of non-goal related future events. Since future thinking is often goal-oriented and leads to greater activation of brain regions involved in prospection, goal-oriented EFT may be associated with greater reductions in DD than general goal-unrelated EFT. The present study (n=104, M age =22.25, SD=3.42; 50% Female) used a between-subjects 2×2 factorial design with type of episodic thinking (Goal, General) and temporal perspective (Episodic future versus recent thinking; EFT vs ERT) as between factors. Results showed a significant reduction in DD for EFT groups (p<0.001, Cohen's d effect size=0.89), and goal-EFT was more effective than general-EFT on reducing DD (p=0.03, d=0.64). Copyright © 2017 Elsevier Inc. All rights reserved.

  13. Are predictors of future suicide attempts and the transition from suicidal ideation to suicide attempts shared or distinct: a 12-month prospective study among patients with depressive disorders.

    PubMed

    Chan, Lai Fong; Shamsul, Azhar Shah; Maniam, Thambu

    2014-12-30

    Our study aimed to examine the interplay between clinical and social predictors of future suicide attempt and the transition from suicidal ideation to suicide attempt in depressive disorders. Sixty-six Malaysian inpatients with a depressive disorder were assessed at index admission and within 1 year for suicide attempt, suicidal ideation, depression severity, life event changes, treatment history and relevant clinical and socio-demographic factors. One-fifth of suicidal ideators transitioned to a future suicide attempt. All future attempters (12/66) had prior ideation and 83% of attempters had a prior attempt. The highest risk for transitioning from ideation to attempt was 5 months post-discharge. Single predictor models showed that previous psychiatric hospitalization and ideation severity were shared predictors of future attempt and ideation to attempt transition. Substance use disorders (especially alcohol) predicted future attempt and approached significance for the transition process. Low socio-economic status predicted the transition process while major personal injury/illness predicted future suicide attempt. Past suicide attempt, subjective depression severity and medication compliance predicted only future suicide attempt. The absence of prior suicide attempt did not eliminate the risk of future attempt. Given the limited sample, future larger studies on mechanisms underlying the interactions of such predictors are needed. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  14. Long-term Recall of Time to Pregnancy.

    PubMed

    Jukic, Anne Marie Z; McConnaughey, D Robert; Weinberg, Clarice R; Wilcox, Allen J; Baird, Donna D

    2016-09-01

    Despite the widespread use of retrospectively reported time to pregnancy to evaluate fertility either as an outcome or as a risk factor for chronic disease, only two small studies have directly compared prospective data with later recall. The North Carolina Early Pregnancy Study (1982-1986) collected prospective time-to-pregnancy data from the beginning of participants' pregnancy attempt. In 2010, (24-28 years later) women were sent a questionnaire including lifetime reproductive history that asked about all prior times to pregnancy. Of the 202 women with prospective time-to-pregnancy data, 76% provided recalled time to pregnancy. A lower proportion of women with times to pregnancy ≥3 cycles provided a recalled time to pregnancy than women with times to pregnancy <3 cycles. Also, high gravidity or parity was associated with a lower likelihood of providing a recalled time to pregnancy. Women with very short or very long times to pregnancy (1 cycle or ≥13 cycles) had good recall of time to pregnancy. Positive predictive values of 1 or ≥13 cycles were 73% and 68%, respectively, while positive predictive values for other categories of time to pregnancy ranged from 38% to 58%. The weighted kappa statistic for recalled versus prospective time to pregnancy was 0.72 (95% confidence interval: 0.65, 0.79). Recalled time to pregnancy showed good agreement with prospective time to pregnancy. Informative missingness must be considered when imputing recalled time to pregnancy. Associations observed in future studies can be corrected for misclassification.

  15. Statistics of petroleum exploration in the Caribbean, Latin America, Western Europe, the Middle East, Africa, non-communist Asia, and the southwestern Pacific

    USGS Publications Warehouse

    Attanasi, E.D.; Root, David H.

    1993-01-01

    This circular presents a summary of the geographic location, amount, and results of petroleum exploration, including an atlas showing explored and delineated prospective areas through 1990. The data show that wildcat well drilling has continued through the last decade to expand the prospective area by about 40,000 to 50,000 square miles per year. However, the area delineated by 1970, which represents only about one-third of the prospective area delineated to date, contains about 80 percent of the oil discovered to date. This discovery distribution suggests that, from an overall prospective, the industry was successful in delineating the most productive areas early. The price increases of the 1970's and 1980's allowed the commercial exploration and development of fields in high-cost areas, such as the North Sea and Campos Basin, Brazil. Data on natural-gas discoveries also indicate that gas will be supplying an increasing share of the worldwide energy market. The size distribution of petroleum provinces is highly skewed. The skewed distribution and the stability in province size orderings suggest that intense exploration in identified provinces will not change the distribution of oil within the study area. Although evidence of the field-growth phenomenon outside the United States and Canada is presented, the data are not yet reliable enough for projecting future growth. The field-growth phenomenon implies not only that recent discoveries are substantially understated, but that field growth could become the dominant source of additions to proved reserves in the future.

  16. First results with charmless two-body B-decays at LHCb, and future prospects

    ScienceCinema

    Vagnoni, Vincenzo

    2018-04-27

    LHCb is an experiment which is designed to perform flavour physics measurements at the LHC. Charged two-body charmless B decays (e.g. B^0 -> Kpi, pipi, B_s->KK, etc) receive significant contributions from loop diagrams and are thus sensitive probes of New Physics. Study of these modes is therefore an important physics goal of LHCb. First results will be presented, using around 37 pb^{-1} of data collected at \\sqrt{s}=7 TeV in 2010. These results illustrate the power of the LHCb trigger system and particle identification capabilities of the RICH detectors in isolating clean samples of each final state, and include preliminary measurements of direct CP-violation in certain key modes. The prospects for these measurements in the coming run will be presented. A brief survey will also be given of results and prospect in other areas of the LHCb physics programme.

  17. Intracranial Pressure and Its Relationship to Glaucoma: Current Understanding and Future Directions

    PubMed Central

    ROY CHOWDHURY, Uttio; FAUTSCH, Michael P.

    2015-01-01

    Retrospective and prospective studies looking at the role of cerebrospinal fluid pressure (CSFP)/intracranial pressure (ICP) have stimulated new theories and hypotheses regarding the underlying causal events for glaucoma. Most recently, studies supporting a low CSFP/ICP as a risk factor for glaucoma have been published. This review summarizes the current understanding of CSFP/ICP and its potential role in the pathogenicity of the disease. PMID:27350948

  18. Active choice but not too active: Public perspectives on biobank consent models

    PubMed Central

    Simon, Christian M.; L’Heureux, Jamie; Murray, Jeffrey C.; Winokur, Patricia; Weiner, George; Newbury, Elizabeth; Shinkunas, Laura; Zimmerman, Bridget

    2013-01-01

    Purpose Despite important recent work, US public attitudes toward specific biobank consent models are not well understood. Public opinion data can help shape efforts to develop ethically sound and publicly trusted mechanisms for informing and consenting prospective biobank donors. The purpose of this study was to explore public perspectives toward a range of consent models currently being used or considered for use among comprehensive US biobanks. Methods The study used an exploratory mixed-methods design, using focus groups and telephone surveys. Eligible participants were English-speaking residents in the catchment area of a comprehensive biobank being developed at the University of Iowa. Results Forty-eight participants in seven focus groups and 751 survey participants were recruited. Biobanks were unfamiliar to almost all study participants but were seen as valuable resources. Most focus group (63%) and survey (67%) participants preferred a prospective opt-in over an opt-out consent approach. Broad, research-unspecific consent was preferred over categorical and study-specific consent models for purposes of approving future research use. Conclusion Many individuals may want to make an active and informed choice at the point of being approached for biobank participation but are prepared to consent broadly to future research use and to forego additional choices as a result. PMID:21555942

  19. Prospective faculty developing understanding of teaching and learning processes in science

    NASA Astrophysics Data System (ADS)

    Pareja, Jose I.

    Historically, teaching has been considered a burden by many academics at institutions of higher education, particularly research scientists. Furthermore, university faculty and prospective faculty often have limited exposure to issues associated with effective teaching and learning. As a result, a series of ineffective teaching and learning strategies are pervasive in university classrooms. This exploratory case study focuses on four biology graduate teaching fellows (BGF) who participated in a National Science Foundation (NSF) GK-12 Program. Such programs were introduced by NSF to enhance the preparation of prospective faculty for their future professional responsibilities. In this particular program, BGF were paired with high school biology teachers (pedagogical mentors) for at least one year. During this yearlong partnership, BGF were involved in a series of activities related to teaching and learning ranging from classroom teaching, tutoring, lesson planning, grading, to participating in professional development conferences and reflecting upon their practices. The purpose of this study was to examine the changes in BGF understanding of teaching and learning processes in science as a function of their pedagogical content knowledge (PCK). In addition, the potential transfer of this knowledge between high school and higher education contexts was investigated. The findings of this study suggest that understanding of teaching and learning processes in science by the BGF changed. Specific aspects of the BGF involvement in the program (such as classroom observations, practice teaching, communicating with mentors, and reflecting upon one's practice) contributed to PCK development. In fact, there is evidence to suggest that constant reflection is critical in the process of change. Concurrently, BGFs enhanced understanding of science teaching and learning processes may be transferable from the high school context to the university context. Future research studies should be designed to explore explicitly this transfer phenomenon.

  20. DNA methylation of loci within ABCG1 and PHOSPHO1 in blood DNA is associated with future type 2 diabetes risk.

    PubMed

    Dayeh, Tasnim; Tuomi, Tiinamaija; Almgren, Peter; Perfilyev, Alexander; Jansson, Per-Anders; de Mello, Vanessa D; Pihlajamäki, Jussi; Vaag, Allan; Groop, Leif; Nilsson, Emma; Ling, Charlotte

    2016-07-02

    Identification of subjects with a high risk of developing type 2 diabetes (T2D) is fundamental for prevention of the disease. Consequently, it is essential to search for new biomarkers that can improve the prediction of T2D. The aim of this study was to examine whether 5 DNA methylation loci in blood DNA (ABCG1, PHOSPHO1, SOCS3, SREBF1, and TXNIP), recently reported to be associated with T2D, might predict future T2D in subjects from the Botnia prospective study. We also tested if these CpG sites exhibit altered DNA methylation in human pancreatic islets, liver, adipose tissue, and skeletal muscle from diabetic vs. non-diabetic subjects. DNA methylation at the ABCG1 locus cg06500161 in blood DNA was associated with an increased risk for future T2D (OR = 1.09, 95% CI = 1.02-1.16, P-value = 0.007, Q-value = 0.018), while DNA methylation at the PHOSPHO1 locus cg02650017 in blood DNA was associated with a decreased risk for future T2D (OR = 0.85, 95% CI = 0.75-0.95, P-value = 0.006, Q-value = 0.018) after adjustment for age, gender, fasting glucose, and family relation. Furthermore, the level of DNA methylation at the ABCG1 locus cg06500161 in blood DNA correlated positively with BMI, HbA1c, fasting insulin, and triglyceride levels, and was increased in adipose tissue and blood from the diabetic twin among monozygotic twin pairs discordant for T2D. DNA methylation at the PHOSPHO1 locus cg02650017 in blood correlated positively with HDL levels, and was decreased in skeletal muscle from diabetic vs. non-diabetic monozygotic twins. DNA methylation of cg18181703 (SOCS3), cg11024682 (SREBF1), and cg19693031 (TXNIP) was not associated with future T2D risk in subjects from the Botnia prospective study.

  1. Nitro drugs for the treatment of trypanosomatid diseases: past, present, and future prospects

    PubMed Central

    Patterson, Stephen; Wyllie, Susan

    2014-01-01

    There is an urgent need for new, safer, and effective treatments for the diseases caused by the protozoan parasites Trypanosoma brucei, Trypanosoma cruzi, and Leishmania spp. In the search for more effective drugs to treat these ‘neglected diseases’ researchers have chosen to reassess the therapeutic value of nitroaromatic compounds. Previously avoided in drug discovery programs owing to potential toxicity issues, a nitro drug is now being used successfully as part of a combination therapy for human African trypanosomiasis. We describe here the rehabilitation of nitro drugs for the treatment of trypanosomatid diseases and discuss the future prospects for this compound class. PMID:24776300

  2. Future prospects for measurements of mass hierarchy and CP violation

    NASA Astrophysics Data System (ADS)

    Lang, Karol

    2015-03-01

    We present a brief overview of current plans to pursue two challenging goals, resolution of the neutrino mass hierarchy and determination of the CP phase of the PMNS neutrino mixing matrix. Future prospects include large atmospheric experiments, PINGU, ORCA, and INO-ICAL, medium baseline reactor experiments, JUNO and RENO- 50, and long baseline accelerator experiments, LBNE, LBNO, and Hyper-Kamiokande. There are also new initiatives emerging, ESSνSB at the European Spallation Source, and CHIPS in the NuMI neutrino beam. This is a multifaceted, vigorous, and technically difficult world-wide program. It will likely take more than a decade to start reaping its benefits.

  3. [Current advances and future prospects of genome editing technology in the field of biomedicine.

    PubMed

    Sakuma, Tetsushi

    Genome editing technology can alter the genomic sequence at will, contributing the creation of cellular and animal models of human diseases including hereditary disorders and cancers, and the generation of the mutation-corrected human induced pluripotent stem cells for ex vivo regenerative medicine. In addition, novel approaches such as drug development using genome-wide CRISPR screening and cancer suppression using epigenome editing technology, which can change the epigenetic modifications in a site-specific manner, have also been conducted. In this article, I summarize the current advances and future prospects of genome editing technology in the field of biomedicine.

  4. Polymeric Nanocomposite Membranes for Next Generation Pervaporation Process: Strategies, Challenges and Future Prospects.

    PubMed

    Roy, Sagar; Singha, Nayan Ranjan

    2017-09-08

    Pervaporation (PV) has been considered as one of the most active and promising areas in membrane technologies in separating close boiling or azeotropic liquid mixtures, heat sensitive biomaterials, water or organics from its mixtures that are indispensable constituents for various important chemical and bio-separations. In the PV process, the membrane plays the most pivotal role and is of paramount importance in governing the overall efficiency. This article evaluates and collaborates the current research towards the development of next generation nanomaterials (NMs) and embedded polymeric membranes with regard to its synthesis, fabrication and application strategies, challenges and future prospects.

  5. Polymeric Nanocomposite Membranes for Next Generation Pervaporation Process: Strategies, Challenges and Future Prospects

    PubMed Central

    Singha, Nayan Ranjan

    2017-01-01

    Pervaporation (PV) has been considered as one of the most active and promising areas in membrane technologies in separating close boiling or azeotropic liquid mixtures, heat sensitive biomaterials, water or organics from its mixtures that are indispensable constituents for various important chemical and bio-separations. In the PV process, the membrane plays the most pivotal role and is of paramount importance in governing the overall efficiency. This article evaluates and collaborates the current research towards the development of next generation nanomaterials (NMs) and embedded polymeric membranes with regard to its synthesis, fabrication and application strategies, challenges and future prospects. PMID:28885591

  6. Prospective Optimization with Limited Resources

    PubMed Central

    Snider, Joseph; Lee, Dongpyo; Poizner, Howard; Gepshtein, Sergei

    2015-01-01

    The future is uncertain because some forthcoming events are unpredictable and also because our ability to foresee the myriad consequences of our own actions is limited. Here we studied how humans select actions under such extrinsic and intrinsic uncertainty, in view of an exponentially expanding number of prospects on a branching multivalued visual stimulus. A triangular grid of disks of different sizes scrolled down a touchscreen at a variable speed. The larger disks represented larger rewards. The task was to maximize the cumulative reward by touching one disk at a time in a rapid sequence, forming an upward path across the grid, while every step along the path constrained the part of the grid accessible in the future. This task captured some of the complexity of natural behavior in the risky and dynamic world, where ongoing decisions alter the landscape of future rewards. By comparing human behavior with behavior of ideal actors, we identified the strategies used by humans in terms of how far into the future they looked (their “depth of computation”) and how often they attempted to incorporate new information about the future rewards (their “recalculation period”). We found that, for a given task difficulty, humans traded off their depth of computation for the recalculation period. The form of this tradeoff was consistent with a complete, brute-force exploration of all possible paths up to a resource-limited finite depth. A step-by-step analysis of the human behavior revealed that participants took into account very fine distinctions between the future rewards and that they abstained from some simple heuristics in assessment of the alternative paths, such as seeking only the largest disks or avoiding the smaller disks. The participants preferred to reduce their depth of computation or increase the recalculation period rather than sacrifice the precision of computation. PMID:26367309

  7. Prospective Optimization with Limited Resources.

    PubMed

    Snider, Joseph; Lee, Dongpyo; Poizner, Howard; Gepshtein, Sergei

    2015-09-01

    The future is uncertain because some forthcoming events are unpredictable and also because our ability to foresee the myriad consequences of our own actions is limited. Here we studied how humans select actions under such extrinsic and intrinsic uncertainty, in view of an exponentially expanding number of prospects on a branching multivalued visual stimulus. A triangular grid of disks of different sizes scrolled down a touchscreen at a variable speed. The larger disks represented larger rewards. The task was to maximize the cumulative reward by touching one disk at a time in a rapid sequence, forming an upward path across the grid, while every step along the path constrained the part of the grid accessible in the future. This task captured some of the complexity of natural behavior in the risky and dynamic world, where ongoing decisions alter the landscape of future rewards. By comparing human behavior with behavior of ideal actors, we identified the strategies used by humans in terms of how far into the future they looked (their "depth of computation") and how often they attempted to incorporate new information about the future rewards (their "recalculation period"). We found that, for a given task difficulty, humans traded off their depth of computation for the recalculation period. The form of this tradeoff was consistent with a complete, brute-force exploration of all possible paths up to a resource-limited finite depth. A step-by-step analysis of the human behavior revealed that participants took into account very fine distinctions between the future rewards and that they abstained from some simple heuristics in assessment of the alternative paths, such as seeking only the largest disks or avoiding the smaller disks. The participants preferred to reduce their depth of computation or increase the recalculation period rather than sacrifice the precision of computation.

  8. Mammographic density and breast cancer risk: current understanding and future prospects

    PubMed Central

    2011-01-01

    Variations in percent mammographic density (PMD) reflect variations in the amounts of collagen and number of epithelial and non-epithelial cells in the breast. Extensive PMD is associated with a markedly increased risk of invasive breast cancer. The PMD phenotype is important in the context of breast cancer prevention because extensive PMD is common in the population, is strongly associated with risk of the disease, and, unlike most breast cancer risk factors, can be changed. Work now in progress makes it likely that measurement of PMD will be improved in the near future and that understanding of the genetics and biological basis of the association of PMD with breast cancer risk will also improve. Future prospects for the application of PMD include mammographic screening, risk prediction in individuals, breast cancer prevention research, and clinical decision making. PMID:22114898

  9. The Neurocognitive Development of Episodic Prospection and Its Implications for Academic Achievement

    ERIC Educational Resources Information Center

    Prabhakar, Janani; Coughlin, Christine; Ghetti, Simona

    2016-01-01

    Episodic prospection is the ability to mentally simulate personal future events that are rich in contextual detail and plausible for the individual. It therefore incorporates episodic information (who, what, where, and when of a particular event), as well as details about one's self (e.g., knowledge, goals, motivations and desires). The ability to…

  10. Current Status and Future Prospects of Upper-Secondary Vocational Education in Taiwan.

    ERIC Educational Resources Information Center

    Lee, Lung-Sheng Steven

    The current status and prospects of upper secondary vocational education (USVE) in Taiwan were reviewed. The following were among the key findings: (1) in Taiwan, USVE is offered in all vocational high schools (VHS), the occupational programs in all comprehensive high schools (CHS), and some senior high schools (SHS); (2) students in VHS…

  11. At the Precipice: A Prospective Exploration of Medical Students' Expectations of the Pre-Clerkship to Clerkship Transition

    ERIC Educational Resources Information Center

    Soo, Jason; Brett-MacLean, Pamela; Cave, Marie-Therese; Oswald, Anna

    2016-01-01

    Medical learners face many challenging transitions. We prospectively explored students' perceptions of their upcoming transition to clerkship and their future professional selves. In 2013, 160/165 end-of-second-year medical students wrote narrative reflections and 79/165 completed a questionnaire on their perceptions of their upcoming transition…

  12. [Application of ecosystem service value in land use change research: Bottlenecks and prospects].

    PubMed

    Zhang, Zhou; Wu, Ci-Fang; Tan, Rong

    2013-02-01

    In recent years, the application of ecosystem service value in land use change research is a hot topic in many famous international journals. However, policy makers are seldom taking into account the achievements of the related studies in practice. This paper summarized the three main bottlenecks in applying ecosystem service value in land management practices, i. e., the difficulty in measuring the service values, the complexity of driving factors, and the bias of evaluation criteria. Some solutions on the bottlenecks were provided, and the future research directions in China were prospected. It was suggested that in the studies of land use change based on ecosystem service value, it would be more appropriate to adopt comparative analysis method in small scale case studies, especially focusing on the natural ecological resources and the excessive loss of their values.

  13. Prospective Cohort Study of Work Functioning Impairment and Subsequent Absenteeism Among Japanese Workers.

    PubMed

    Fujino, Yoshihisa; Shazuki, Shuichiro; Izumi, Hiroyuki; Uehara, Masamichi; Muramatsu, Keiji; Kubo, Tatsuhiko; Oyama, Ichiro; Matsuda, Shinya

    2016-07-01

    This study examined the association of work functioning impairment as measured by work functioning impairment scale (WFun) and subsequent sick leave. A prospective cohort study was conducted at a manufacturer in Japan, and 1263 employees participated. Information on sick leave was gathered during an 18-month follow-up period. The hazard ratios (HRs) of long-term sick leave were substantially increased for those with a WFun score greater than 25 (HR = 3.99, P = 0.003). The incidence rate ratios (IRRs) of days of short-term absence gradually increased as scores of WFun increased (IRR = 1.18, P < 0.001 in the subjects with WFun of over 25 comparing with those with WFun of 14 or less). Assessing work functioning impairment is a useful way of classifying risk for future sick leave among employees.

  14. Characteristics of future air cargo demand and impact on aircraft development: A report on the Cargo/Logistic Airlift Systems Study (CLASS) project

    NASA Technical Reports Server (NTRS)

    Whitehead, A. H., Jr.

    1978-01-01

    Current domestic and international air cargo operations are studied and the characteristics of 1990 air cargo demand are postulated from surveys conducted at airports and with shippers, consignees, and freight forwarders as well as air, land, and ocean carriers. Simulation and route optimization programs are exercised to evaluate advanced aircraft concepts. The results show that proposed changes in the infrastructure and improved cargo loading efficiencies are as important enhancing the prospects of air cargo growth as is the advent of advanced freighter aircraft. Potential reductions in aircraft direct operating costs are estimated and related to future total revenue. Service and cost elasticities are established and utilized to estimate future potential tariff reductions that may be realized through direct and indirect operating cost reductions and economies of scale.

  15. Comment: On the World's Energy Situation.

    ERIC Educational Resources Information Center

    Kouzminow, V. A.

    1979-01-01

    Reviewed, in this editorial, are the present world energy situation and estimates of the prospects of supplying mankind with the amount of energy necessary for future socioeconomic development. Stressed is the role of different energy sources in the present and future energy balance of the world. (BT)

  16. U.S. Population Growth: Prospects and Policy.

    ERIC Educational Resources Information Center

    McFalls, Joseph A., Jr.; And Others

    1984-01-01

    The Commission on Population Growth and the American Future concluded that zero population growth (ZPG) is in the best interest of the United States. To achieve ZPG in the future, the United States must keep fertility and net immigration relatively low. Practical problems are discussed. (RM)

  17. Trade Publishing: A Report from the Front.

    ERIC Educational Resources Information Center

    Fister, Barbara

    2001-01-01

    Reports on the current condition of trade publishing and its future prospects based on interviews with editors, publishers, agents, and others. Discusses academic libraries and the future of trade publishing, including questions relating to electronic books, intellectual property, and social and economic benefits of sharing information…

  18. High-energy Neutrino Emission from Short Gamma-Ray Bursts: Prospects for Coincident Detection with Gravitational Waves

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kimura, Shigeo S.; Murase, Kohta; Mészáros, Peter

    We investigate current and future prospects for coincident detection of high-energy neutrinos and gravitational waves (GWs). Short gamma-ray bursts (SGRBs) are believed to originate from mergers of compact star binaries involving neutron stars. We estimate high-energy neutrino fluences from prompt emission, extended emission (EE), X-ray flares, and plateau emission, and we show that neutrino signals associated with the EE are the most promising. Assuming that the cosmic-ray loading factor is ∼10 and the Lorentz factor distribution is lognormal, we calculate the probability of neutrino detection from EE by current and future neutrino detectors, and we find that the quasi-simultaneous detectionmore » of high-energy neutrinos, gamma-rays, and GWs is possible with future instruments or even with current instruments for nearby SGRBs having EE. We also discuss stacking analyses that will also be useful with future experiments such as IceCube-Gen2.« less

  19. Energy: the impact of availability and prices on future business prospects. [Collection of 12 papers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Peelle, D.M.

    1975-01-01

    This collection includes twelve papers, all but one being presented at an August 1974 seminar. These are entitled Energy: Policy, Availability and Prices, Harry R. Hall; Public Policy and the Energy Crisis, Edward J. Mitchell; How Federal Price and Allocation Controls on Oil Have Worsened the Energy Crisis, William A. Johnson; Energy Availability in the Near and Long-Range Future, R.R. Wright; Consideration of Natural Gas Supply for Michigan, Donald L. Katz; The Outlook for Coal, Robert V. Price; Electricity: Future Availability and Cost, G. L. Heins; Solar Energy Research and Development, F. Tom Sparrow; Energy in the Automobile, Doron K.more » Samples; Energy and Future Business Prospects: Implication for Feedstocks-Using Industries, William H. Shaker; Energy Conservation in the Processing Industries, Alfred F. Waterland; and Energy Management: Guidelines and Case Histories, G. N. Tiberio. Letter from OPEC is a dissertation by Joseph Kraft on a visit to OPEC headquarters in Vienna. (MCW)« less

  20. C P -violation in the two Higgs doublet model: From the LHC to EDMs

    NASA Astrophysics Data System (ADS)

    Chen, Chien-Yi; Li, Hao-Lin; Ramsey-Musolf, Michael

    2018-01-01

    We study the prospective sensitivity to C P -violating two Higgs doublet models from the 14 TeV LHC and future electric dipole moment (EDM) experiments. We concentrate on the search for a resonant heavy Higgs that decays to a Z boson and a SM-like Higgs h , leading to the Z (ℓℓ)h (b b ¯ ) final state. The prospective LHC reach is analyzed using the Boosted Decision Tree method. We illustrate the complementarity between the LHC and low energy EDM measurements and study the dependence of the physics reach on the degree of deviation from the alignment limit. In all cases, we find that there exists a large part of parameter space that is sensitive to both EDMs and LHC searches.

  1. Orthodontics as a prospective career choice among undergraduate dental students: A prospective study.

    PubMed

    Sam, George

    2015-01-01

    The purposes of this study were to investigate the factors influencing the career choice of dental students and to identify the future life plans of the students at Prince Sattam Bin Abdulaziz University Dental College who had chosen orthodontics as their future specialty. An epidemiological descriptive survey was conducted using a set of questionnaire among the second year to fourth year students at Prince Sattam Bin Abdulaziz University, Al Kharj, Saudi Arabia. Data were categorized by demographic variables and were analyzed with statistical methods using descriptive statistical analysis. The most important factor influencing the decision to pursue specialty in orthodontics was considering that "orthodontics is intellectually challenging" (23%), followed by "previous positive experience" (15%). The decision to become an orthodontist was made by 3.7% of the respondents in the first year of their course, 44.4% in the second year of their study, 11.1% during the third year of their study, 25.9% during the fourth year of their study, while none of them had made their decision during the final year of their dental school studies. Only one student (3.7) said he planned to work in a private college in an academic setting, five students (18.5%) had plans to do private practice, two students indicated that they would work for the Ministry of Health, while most students (40.7%) reported that they were planning to try a combination of all of the above. Six students (22.2%) remained undecided. Majority of the students who had chosen orthodontics as their future specialty of choice at Sattam Bin Abdulaziz University Dental College, Saudi Arabia had taken up this specialty as they felt that orthodontics was intellectually challenging.

  2. Eccentric Knee Flexor Strength and Risk of Hamstring Injuries in Rugby Union: A Prospective Study.

    PubMed

    Bourne, Matthew N; Opar, David A; Williams, Morgan D; Shield, Anthony J

    2015-11-01

    Hamstring strain injuries (HSIs) represent the most common cause of lost playing time in rugby union. Eccentric knee flexor weakness and between-limb imbalance in eccentric knee flexor strength are associated with a heightened risk of HSIs in other sports; however, these variables have not been explored in rugby union. To determine if lower levels of eccentric knee flexor strength or greater between-limb imbalance in this parameter during the Nordic hamstring exercise are risk factors for HSIs in rugby union. Cohort study; Level of evidence, 2. This prospective study was conducted over the 2014 Super Rugby and Queensland Rugby Union seasons. In total, 178 rugby union players (mean age, 22.6 ± 3.8 years; mean height, 185.0 ± 6.8 cm; mean weight, 96.5 ± 13.1 kg) had their eccentric knee flexor strength assessed using a custom-made device during the preseason. Reports of previous hamstring, quadriceps, groin, calf, and anterior cruciate ligament injuries were also obtained. The main outcome measure was the prospective occurrence of HSIs. Twenty players suffered at least 1 HSI during the study period. Players with a history of HSIs had a 4.1-fold (95% CI, 1.9-8.9; P = .001) greater risk of subsequent HSIs than players without such a history. Between-limb imbalance in eccentric knee flexor strength of ≥15% and ≥20% increased the risk of HSIs by 2.4-fold (95% CI, 1.1-5.5; P = .033) and 3.4-fold (95% CI, 1.5-7.6; P = .003), respectively. Lower eccentric knee flexor strength and other prior injuries were not associated with an increased risk of future HSIs. Multivariate logistic regression revealed that the risk of reinjuries was augmented in players with strength imbalances. Previous HSIs and between-limb imbalance in eccentric knee flexor strength were associated with an increased risk of future HSIs in rugby union. These results support the rationale for reducing imbalance, particularly in players who have suffered a prior HSI, to mitigate the risk of future injuries. © 2015 The Author(s).

  3. Adapting nurse competence to future patient needs using Checkland's Soft Systems Methodology.

    PubMed

    Železnik, Danica; Kokol, Peter; Blažun Vošner, Helena

    2017-01-01

    New emerging technologies, health globalization, demographic change, new healthcare paradigms, advances in healthcare delivery and social networking will change the needs of patients in the future and consequently will require that new knowledge, competence and skill sets be acquired by nurses. Checkland's Soft Systems Methodology, focusing on the enriched CATWOE and PQR elements of the root definitions, combined with our own developed "Too much - Too little constraint" approach was used to devise impending knowledge, competence and skill sets. The analysis revealed ten needs among patients of the future, 63 constraints and 18 knowledge, competence and skill sets for the future nurse. The completed study showed that SSM is an appropriate tool for high level structuring of a "messy" real-world problem situation to meet prospective nursing challenges. Copyright © 2016 Elsevier Ltd. All rights reserved.

  4. US nonfuel mineral exploration: Selected findings for 1995-2009 from the USGS

    USGS Publications Warehouse

    Wilburn, David R.; Bleiwas, Donald I.

    2012-01-01

    The U.S. Geological Survey (USGS) has been systematically monitoring global nonfuel mineral exploration activities to anticipate the location and quantity of future nonfuel minerals supply for about 100 commodities, with an emphasis on precious and base metals. Since 1995, the USGS has developed an annual list of 100 noteworthy prospects that were considered to have a high level of potential for near-term development based on such criteria as intensity of drilling, level of capital investment, and size of resource. This study reviews the status of the U.S. sites included on these lists as of July 2011 and addresses domestic prospects not included on the lists that have come into production since 1995.

  5. Gallium arsenide solar cells-status and prospects for use in space

    NASA Technical Reports Server (NTRS)

    Brandhorst, H. W.; Flood, D.; Weinberg, I.

    1981-01-01

    Gallium Arsenide solar cells now equal or surpass the ubiquitous silicon solar cells in efficiency, radiation resistance, annealability, and in the capability for producing usable power output at elevated temperatures. NASA has developed a long-range research and development program to capitalize on these manifold advantages. In this paper we review the current state and future prospects for R&D in this promising solar cell material, and indicate the progress being made toward development of GaAs cells suitable for a variety of space missions. Results are presented from studies which demonstrate conclusively that GaAs cells can provide a net mission cost and weight savings for certain important mission classes.

  6. Resource Prospector: An Update on the Lunar Volatiles Prospecting and ISRU Demonstration Mission

    NASA Technical Reports Server (NTRS)

    Colaprete, A.; Elphic, R.; Andrews, D.; Trimble, J.; Bluethmann, B.; Quinn, J.; Chavers, G.

    2016-01-01

    Over the last two decades a wealth of new observations of the moon have demonstrated a lunar water system dramatically more complex and rich than was deduced following the Apollo era. Lunar water, and other volatiles, have the potential to be a valuable or enabling resource for future exploration. The NASA Human Exploration and Operations Mission Directorate (HEOMD) have selected a lunar volatiles prospecting mission for a concept study and potential flight in CY2021. The mission includes a rover-borne payload that (1) can locate surface and near-subsurface volatiles, (2) excavate and analyze samples of the volatile-bearing regolith, and (3) demonstrate the form, extractability and usefulness of the materials.

  7. Resource Prospector: An Update on the Lunar Volatiles Prospecting and ISRU Demonstration Mission

    NASA Technical Reports Server (NTRS)

    Colaprete, A.; Elphic, R.; Andrews, D.; Trimble, J.; Bluethmann, B.; Quinn, J.; Chavers, G.

    2017-01-01

    Over the last two decades a wealth of new observations of the moon have demonstrated a lunar water system dramatically more complex and rich than was deduced following the Apollo era. Lunar water, and other volatiles, have the potential to be a valuable or enabling resource for future exploration. The NASA Human Exploration and Operations Mission Directorate (HEOMD) have selected a lunar volatiles prospecting mission for a concept study and potential flight in CY2021. The mission includes a rover-borne payload that (1) can locate surface and near-subsurface volatiles, (2) excavate and analyze samples of the volatile- bearing regolith, and (3) demonstrate the form, extractability and usefulness of the materials.

  8. International Schools: Current Issues and Future Prospects. Oxford Studies in Comparative Education

    ERIC Educational Resources Information Center

    Hayden, Mary, Ed.; Thompson, Jeff, Ed.

    2016-01-01

    The foundation of the first international schools of the modern era well over a century ago, and their burgeoning growth over recent years, provides the context in this book for a series of personal perspectives written by some of those who have been involved centrally in their development. As the schools themselves have increased not only in…

  9. Prospects for the Faculty Labor Market in the 1990s: A Clemson University Perspective.

    ERIC Educational Resources Information Center

    Ulbrich, Holley

    Through a faculty retirement survey and a review of the literature, Clemson University, South Carolina, studied the future labor market for college faculty. The survey was administered to 1,250 faculty at the university in Fall, 1991. Fifty-six responded with data indicating that the College of Sciences, and the College of Agricultural Sciences…

  10. New sensor technologies in quality evaluation of Chinese materia medica: 2010-2015.

    PubMed

    Miao, Xiaosu; Cui, Qingyu; Wu, Honghui; Qiao, Yanjiang; Zheng, Yanfei; Wu, Zhisheng

    2017-03-01

    New sensor technologies play an important role in quality evaluation of Chinese materia medica (CMM) and include near-infrared spectroscopy, chemical imaging, electronic nose and electronic tongue. This review on quality evaluation of CMM and the application of the new sensors in this assessment is based on studies from 2010 to 2015, with prospects and opportunities for future research.

  11. The Current Status and Future Prospects of Corporate e-Learning in Korea

    ERIC Educational Resources Information Center

    Lim, Cheolil

    2007-01-01

    Corporate e-Learning in Korea has grown rapidly over the previous six years (2000-2005). This study argues that the main cause of this heightened interest in corporate e-Learning in Korea was not that companies needed to provide high-quality training programs through the Internet, but rather that the government took initiative to transform the…

  12. The Status and Future Prospects Educational Development: A Historical Treatment. Center Technical Paper No. 13.

    ERIC Educational Resources Information Center

    Wasik, John L.

    This study focuses on the nature of educational development in the United States as determined by an analysis of the available literature. There is general agreement that educational development has not achieved the status now accorded to the general avocation of research by educators. This appears to be the result of a relatively short history…

  13. Workforce 2000, Silver Bullet or Dud?: Job Structure Changes and Economic Prospects for Black Males in the 1990s.

    ERIC Educational Resources Information Center

    Mincy, Ronald B.

    1991-01-01

    Considers the report "Workforce 2000," a study supported by the U.S. Department of Labor, and assesses criticisms of the predictions it makes of a skills mismatch with no void for educated African-American males to fill. Implications of future labor supply and demand and potential interventions are discussed. (SLD)

  14. Reconstructing the phylogeny of Scolytinae and close allies: Major obstacles and prospects for a solution

    Treesearch

    Bjarte H. Jordal

    2007-01-01

    To enable the resolution of deep phylogenetic divergence in Scolytinae and closely related weevils, several new molecular markers were screened for their phylogenetic potential. The nuclear protein encoding genes, CAD and Arginine Kinase, were particularly promising and will be added to future phylogenetic studies in combination with 28S, COI, and Elongation Factor 1...

  15. Randomized Trial of Treatment for Children with Sexual Behavior Problems: Ten-Year Follow-Up

    ERIC Educational Resources Information Center

    Carpentier, Melissa Y.; Silovsky, Jane F.; Chaffin, Mark

    2006-01-01

    This study prospectively follows 135 children 5-12 years of age with sexual behavior problems from a randomized trial comparing a 12-session group cognitive-behavioral therapy (CBT) with group play therapy and follows 156 general clinic children with nonsexual behavior problems. Ten-year follow-up data on future juvenile and adult arrests and…

  16. Retirement financial planning and the RN: an integrative literature review.

    PubMed

    Keele, Shanna; Alpert, Patricia T

    2013-11-01

    This integrative literature review examined the current research on RN retirement. The review identified 3 critical gaps in knowledge: (a) minimal knowledge regarding the economic impact on RN retirement, (b) incomplete information regarding the demographics of RN retirement, and (c) a scarcity of prospective longitudinal RN workforce studies. Future research must address these gaps to better address RN workforce sustainability.

  17. Retirement Financial Planning and the RN: An Integrative Literature Review.

    PubMed

    Keele, Shanna; Alpert, Patricia T

    2015-10-01

    This integrative literature review examined the current research on RN retirement. The review identified 3 critical gaps in knowledge: (a) minimal knowledge regarding the economic impact on RN retirement, (b) incomplete information regarding the demographics of RN retirement, and (c) a scarcity of prospective longitudinal RN workforce studies. Future research must address these gaps to better address RN workforce sustainability.

  18. An Examination of Accounting Majors' Ethical Decisions before and after an Ethics Course Requirement

    ERIC Educational Resources Information Center

    Rogers, Violet; Smith, Aileen

    2008-01-01

    The increased focus on ethical decision making in the accounting profession has resulted in greater attention being paid to the education of future accountants. Texas is one of the states that requires a State Board approved university course in Accounting Ethics to be on the transcript of prospective CPA candidates. This study reports on research…

  19. Can We Remember Future Actions yet Forget the Last Two Minutes? Study in Transient Global Amnesia

    ERIC Educational Resources Information Center

    Hainselin, Mathieu; Quinette, Peggy; Desgranges, Beatrice; Martinaud, Olivier; Hannequin, Didier; de La Sayette, Vincent; Viader, Fausto; Eustache, Francis

    2011-01-01

    Transient global amnesia (TGA) is a clinical syndrome characterized by the abrupt onset of a massive episodic memory deficit that spares other cognitive functions. If the anterograde dimension is known to be impaired in TGA, researchers have yet to investigate prospective memory (PM)--which involves remembering to perform an intended action at…

  20. Flares in childhood eczema.

    PubMed

    Langan, S M

    2009-01-01

    Eczema is a major public health problem affecting children worldwide. Few studies have directly assessed triggers for disease flares. This paper presents evidence from a published systematic review and a prospective cohort study looking at flare factors in eczema. This systematic review suggested that foodstuffs in selected groups, dust exposure, unfamiliar pets, seasonal variation, stress, and irritants may be important in eczema flares. We performed a prospective cohort study that focused on environmental factors and identified associations between exposure to nylon clothing, dust, unfamiliar pets, sweating, shampoo, and eczema flares. Results from this study also demonstrated some new key findings. First, the effect of shampoo was found to increase in cold weather, and second, combinations of environmental factors were associated with disease exacerbation, supporting a multiple component disease model. This information is likely to be useful to families and may lead to the ability to reduce disease flares in the future.

  1. Fluorescence detection, enumeration and characterization of single circulating cells in vivo: technology, applications and future prospects.

    PubMed

    Hartmann, Carolin; Patil, Roshani; Lin, Charles P; Niedre, Mark J

    2017-11-08

    There are many diseases and biological processes that involve circulating cells in the bloodstream, such as cancer metastasis, immune reaction/inflammation, reproductive medicine, and stem cell therapies. This has driven significant interest in new technologies for the study of circulating cells in small animal research models and clinically. Most currently used methods require drawing and enriching blood samples from the body, but these suffer from a number of limitations. In contrast, "in vivo flow cytometry" (IVFC) refers to set of technologies that allow study of cells directly in the bloodstream of the organism in vivo. In recent years the IVFC field has grown significantly and new techniques have been developed, including fluorescence microscopy, multi-photon, photo-acoustic, and diffuse fluorescence IVFC. In this paper we review recent technical advances in IVFC, with emphasis on instrumentation, contrast mechanisms, and detection sensitivity. We also describe key applications in biomedical research, including cancer research and immunology. Last, we discuss future directions for IVFC, as well as prospects for broader adoption by the biomedical research community and translation to humans clinically. © 2017 Institute of Physics and Engineering in Medicine.

  2. Associations Among Quadriceps Strength and Rate of Torque Development 6 Weeks Post Anterior Cruciate Ligament Reconstruction and Future Hop and Vertical Jump Performance: A Prospective Cohort Study.

    PubMed

    Pua, Yong-Hao; Mentiplay, Benjamin F; Clark, Ross A; Ho, Jia-Ying

    2017-11-01

    Study Design Prospective cohort. Background Quadriceps strength is associated with hop distance and jump height in persons who have undergone anterior cruciate ligament (ACL) reconstruction. However, it is unknown whether the ability to rapidly generate quadriceps torque in the early phase of recovery is associated with future hopping and jumping performance in this population. Objective To evaluate the prospective associations among quadriceps strength and rate of torque development (RTD) and single-leg hop for distance, vertical jump height, vertical ground reaction force (vGRF), and vertical force loading rate during a landing task in persons who have undergone ACL reconstruction. Methods Seventy patients with unilateral ACL reconstruction participated. At 6 weeks post ACL reconstruction, isometric quadriceps strength and RTD were measured using a dynamometer. At 6 months following ACL reconstruction, patients performed the single-leg hop for distance test. Patients also performed the single-leg vertical jump test on a force plate that measured maximum jump height, vGRF, and average loading rate during landing. Results Both quadriceps strength and RTD at 6 weeks post ACL reconstruction were associated with all hopping and jumping measures at 6 months post ACL reconstruction (P≤.04). Single-leg hop distance was associated more closely with quadriceps strength than with quadriceps RTD (P = .05), and vertical jump height and vGRF measures were associated more closely with quadriceps RTD than with quadriceps strength (P = .05 and P<.01, respectively). Both quadriceps measures were associated with loading rate. Conclusion Quadriceps strength and RTD are complementary but distinct predictors of future hopping and jumping performance in persons who have undergone ACL reconstruction. These findings may contribute to improved rehabilitation of patients who are at risk for poor jumping/hopping performance and abnormal knee loading. J Orthop Sports Phys Ther 2017;47(11):845-852. Epub 13 Oct 2017. doi:10.2519/jospt.2017.7133.

  3. Future prospects for space life sciences from a NASA perspective

    NASA Technical Reports Server (NTRS)

    White, Ronald J.; Lujan, Barbara F.

    1989-01-01

    Plans for future NASA research programs in the life sciences are reviewed. Consideration is given to international cooperation in space life science research, the NASA approach to funding life science research, and research opportunities using the Space Shuttle, the Space Station, and Biological Satellites. Several specific programs are described, including the Centrifuge Project to provide a controlled acceleration environment for microgravity studies, the Rhesus Project to conduct biomedical research using rhesus monkeys, and the LifeSat international biosatellite project. Also, the Space Biology Initiative to design and develop life sciences laboratory facilities for the Space Shuttle and the Space Station and the Extended Duration Crew Operations program to study crew adaptation needs are discussed.

  4. Planning for sustainable tourism in southern Pulau Banggi: an assessment of biophysical conditions and their implications for future tourism development.

    PubMed

    Teh, Lydia; Cabanban, Annadel S

    2007-12-01

    A priori assessments of a site's biophysical and socio-economic capacity for accommodating tourism are less common than tourism impact studies. A priori evaluations can provide a contextual understanding of ecological, economic and socio-cultural forces, which shape the prospects for sustainable tourism development at the host destination, and can avert adverse impacts of tourism. We conduct an a priori assessment of the biophysical environment of Pulau Banggi, in the Malaysian state of Sabah for sustainable tourism development. We characterise baseline conditions of the island's marine biodiversity, seasonality, and infrastructure. We then evaluate how existing biophysical conditions will influence options for sustainable tourism development. In particular, we suggest conditions, if there are any, which constitute a limit to future tourism development in terms of compatibility for recreation and resilience to visitor impacts. We find that the biggest constraint is the lack of adequate water and sanitation infrastructure. Blast fishing, although occurring less than once per hour, can potentially destroy the major attraction for tourists. We conclude that while Pulau Banggi possesses natural qualities that are attractive for ecotourism, financial and institutional support must be made available to provide facilities and services that will enable local participation in environmental protection and enhance prospects for future sustainable tourism.

  5. MEDIAL TEMPORAL LOBE CONTRIBUTIONS TO FUTURE THINKING: EVIDENCE FROM NEUROIMAGING AND AMNESIA.

    PubMed

    Verfaellie, Mieke; Race, Elizabeth; Keane, Margaret M

    2012-09-01

    Following early amnesic case reports, there is now considerable evidence suggesting a link between remembering the past and envisioning the future. This link is evident in the overlap in neural substrates as well as cognitive processes involved in both kinds of tasks. While constructing a future narrative requires multiple processes, neuroimaging and lesion data converge on a critical role for the medial temporal lobes (MTL) in retrieving and recombining details from memory in the service of novel simulations. Deficient detail retrieval and recombination may lead to impairments not only in episodic, but also in semantic prospection. MTL contributions to scene construction and mental time travel may further compound impairments in amnesia on tasks that pose additional demands on these processes, but are unlikely to form the core deficit underlying amnesics' cross-domain future thinking impairment. Future studies exploring the role of episodic memory in other forms of self-projection or future-oriented behaviour may elucidate further the adaptive role of memory.

  6. MEDIAL TEMPORAL LOBE CONTRIBUTIONS TO FUTURE THINKING: EVIDENCE FROM NEUROIMAGING AND AMNESIA

    PubMed Central

    Verfaellie, Mieke; Race, Elizabeth; Keane, Margaret M.

    2013-01-01

    Following early amnesic case reports, there is now considerable evidence suggesting a link between remembering the past and envisioning the future. This link is evident in the overlap in neural substrates as well as cognitive processes involved in both kinds of tasks. While constructing a future narrative requires multiple processes, neuroimaging and lesion data converge on a critical role for the medial temporal lobes (MTL) in retrieving and recombining details from memory in the service of novel simulations. Deficient detail retrieval and recombination may lead to impairments not only in episodic, but also in semantic prospection. MTL contributions to scene construction and mental time travel may further compound impairments in amnesia on tasks that pose additional demands on these processes, but are unlikely to form the core deficit underlying amnesics’ cross-domain future thinking impairment. Future studies exploring the role of episodic memory in other forms of self-projection or future-oriented behaviour may elucidate further the adaptive role of memory. PMID:23447709

  7. Evaluating Long-term Outcomes of NHS Stop Smoking Services (ELONS): a prospective cohort study.

    PubMed

    Dobbie, Fiona; Hiscock, Rosemary; Leonardi-Bee, Jo; Murray, Susan; Shahab, Lion; Aveyard, Paul; Coleman, Tim; McEwen, Andy; McRobbie, Hayden; Purves, Richard; Bauld, Linda

    2015-11-01

    NHS Stop Smoking Services (SSSs) provide free at the point of use treatment for smokers who would like to stop. Since their inception in 1999 they have evolved to offer a variety of support options. Given the changes that have happened in the provision of services and the ongoing need for evidence on effectiveness, the Evaluating Long-term Outcomes for NHS Stop Smoking Services (ELONS) study was commissioned. The main aim of the study was to explore the factors that determine longer-term abstinence from smoking following intervention by SSSs. There were also a number of additional objectives. The ELONS study was an observational study with two main stages: secondary analysis of routine data collected by SSSs and a prospective cohort study of service clients. The prospective study had additional elements on client satisfaction, well-being and longer-term nicotine replacement therapy (NRT) use. The setting for the study was SSSs in England. For the secondary analysis, routine data from 49 services were obtained. For the prospective study and its added elements, nine services were involved. The target population was clients of these services. There were 202,804 cases included in secondary analysis and 3075 in the prospective study. A combination of behavioural support and stop smoking medication delivered by SSS practitioners. Abstinence from smoking at 4 and 52 weeks after setting a quit date, validated by a carbon monoxide (CO) breath test. Just over 4 in 10 smokers (41%) recruited to the prospective study were biochemically validated as abstinent from smoking at 4 weeks (which was broadly comparable with findings from the secondary analysis of routine service data, where self-reported 4-week quit rates were 48%, falling to 34% when biochemical validation had occurred). At the 1-year follow-up, 8% of prospective study clients were CO validated as abstinent from smoking. Clients who received specialist one-to-one behavioural support were twice as likely to have remained abstinent than those who were seen by a general practitioner (GP) practice and pharmacy providers [odds ratio (OR) 2.3, 95% confidence interval (CI) 1.2 to 4.6]. Clients who received group behavioural support (either closed or rolling groups) were three times more likely to stop smoking than those who were seen by a GP practice or pharmacy providers (OR 3.4, 95% CI 1.7 to 6.7). Satisfaction with services was high and well-being at baseline was found to be a predictor of abstinence from smoking at longer-term follow-up. Continued use of NRT at 1 year was rare, but no evidence of harm from longer-term use was identified from the data collected. Stop Smoking Services in England are effective in helping smokers to move away from tobacco use. Using the 52-week CO-validated quit rate of 8% found in this study, we estimate that in the year 2012-13 the services supported 36,249 clients to become non-smokers for the remainder of their lives. This is a substantial figure and provides one indicator of the ongoing value of the treatment that the services provide. The study raises a number of issues for future research including (1) examining the role of electronic cigarettes (e-cigarettes) in smoking cessation for service clients [this study did not look at e-cigarette use (except briefly in the longer-term NRT study) but this is a priority for future studies]; (2) more detailed comparisons of rolling groups with other forms of behavioural support; (3) further exploration of the role of practitioner knowledge, skills and use of effective behaviour change techniques in supporting service clients to stop smoking; (4) surveillance of the impact of structural and funding changes on the future development and sustainability of SSSs; and (5) more detailed analysis of well-being over time between those who successfully stop smoking and those who relapse. Further research on longer-term use of non-combustible nicotine products that measures a wider array of biomarkers of smoking-related harm such as lung function tests or carcinogen metabolites. The National Institute for Health Research Health Technology Assessment programme. The UK Centre for Tobacco and Alcohol Studies provided funding for the longer-term NRT study.

  8. 48 CFR 1852.209-71 - Limitation of future contracting.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... that this acquisition may give rise to a potential organizational conflict of interest. Accordingly, the attention of prospective offerors is invited to FAR Subpart 9.5—Organizational Conflicts of Interest. (b) The nature of this conflict is [describe the conflict]. (c) The restrictions upon future...

  9. Conclusions, Reflections, and Prospects for Future Research, Policy, and Programming

    ERIC Educational Resources Information Center

    Clark-Kazak, Christina

    2012-01-01

    This concluding chapter draws together some of the key themes from the contributions and proposes some recommended areas for future research, policy, and programming. It highlights the artificiality of categorization processes related to both migration and childhood that independent child migrants encounter, and problematizes the…

  10. Long-term prospects for developments in space: A scenario approach

    NASA Technical Reports Server (NTRS)

    Brown, W. M.; Kahn, H. D.

    1977-01-01

    Long-term plans for future NASA programs are reported, and some of the following topics are discussed in detail: (1) systematic formulation of space scenarios; (2) the basic international context; (3) potential 21st century space developments; (4) space vehicle developments; and (5) future exploration.

  11. A Differential Deficit in Time- versus Event-based Prospective Memory in Parkinson's Disease

    PubMed Central

    Raskin, Sarah A.; Woods, Steven Paul; Poquette, Amelia J.; McTaggart, April B.; Sethna, Jim; Williams, Rebecca C.; Tröster, Alexander I.

    2010-01-01

    Objective The aim of the current study was to clarify the nature and extent of impairment in time- versus event-based prospective memory in Parkinson's disease (PD). Prospective memory is thought to involve cognitive processes that are mediated by prefrontal systems and are executive in nature. Given that individuals with PD frequently show executive dysfunction, it is important to determine whether these individuals may have deficits in prospective memory that could impact daily functions, such as taking medications. Although it has been reported that individuals with PD evidence impairment in prospective memory, it is still unclear whether they show a greater deficit for time- versus event-based cues. Method Fifty-four individuals with PD and 34 demographically similar healthy adults were administered a standardized measure of prospective memory that allows for a direct comparison of time-based and event-based cues. In addition, participants were administered a series of standardized measures of retrospective memory and executive functions. Results Individuals with PD demonstrated impaired prospective memory performance compared to the healthy adults, with a greater impairment demonstrated for the time-based tasks. Time-based prospective memory performance was moderately correlated with measures of executive functioning, but only the Stroop Neuropsychological Screening Test emerged as a unique predictor in a linear regression. Conclusions Findings are interpreted within the context of McDaniel and Einstein's (2000) multi-process theory to suggest that individuals with PD experience particular difficulty executing a future intention when the cue to execute the prescribed intention requires higher levels of executive control. PMID:21090895

  12. A prospective study of Trichomonas vaginalis and prostate cancer risk among African American men.

    PubMed

    Fowke, Jay H; Han, Xijing; Alderete, J F; Moses, Kelvin A; Signorello, Lisa B; Blot, William J

    2016-04-18

    African Americans (AA) have a higher prevalence of Trichomonas vaginalis (Tv) infection and a higher prostate (PC) risk. Past studies suggest an association between Tv seropositivity and PC, and therefore we prospectively investigated this association among AA men. Incident PC cases were individually matched to controls in a nested case-control study within the Southern Community Cohort Study (SCCS). Primary analysis included 296 PC cases and 497 race-matched controls. Levels of Tv antibody response were measured by ELISA in serum collected at baseline. Tv antibody response did not significantly differ between cases and controls overall or within AA participants (253 AA cases). There were no significant associations or trends between levels of Tv response and PC risk or the diagnosis of aggressive PC. We found no evidence of a prospective association between baseline Tv infection and PC risk in AA men. Tv infection in men may have substantial health implications in HIV transmission and reproductive outcomes, but may not impact future PC risk in AA men at high-risk for PC. Further efforts need to define past vs. present Tv infection and to separate pathophysiology from PC detection.

  13. Remembrance of Things Future: Prospective Memory in Laboratory, Workplace, and Everyday Settings

    NASA Technical Reports Server (NTRS)

    Dismukes, R. Key

    2010-01-01

    In this review, oriented to the human factors community, I will summarize and provide a perspective on recent research and theory on prospective memory. This will not be an exhaustive review of literature, which is already available in two excellent recent books that provide a wealth of detail on the current state of experimental research (Kliegel, McCaniel, & Einstein, 2008; McDaniel & Einstein, 2007; also see Brandimonte, Einstein, & McDaniel, 1996, for a still relevant overview of the field as it was emerging). Rather, I will explore the limits of existing experimental paradigms and theory, Vvilich, in my opinion, fail to capture some critical aspects of performance outside the laboratory. I will also review the relatively few studies in workplace and everyday settings and will discuss several studies that attempt to bridge between the bulk of experimental studies and these few naturalistic studies. Finally, I will describe countermeasures that can reduce vulnerability to forgetting to perform intended tasks, and I will propose a research agenda that would extend existing experimental and theoretical approaches and would support human factors practitioners by generating information on a wide range of issues relevant to prospective memory performance in natural settings.

  14. Are lower levels of cardiorespiratory fitness associated with incident depression? A systematic review of prospective cohort studies.

    PubMed

    Schuch, Felipe B; Vancampfort, Davy; Sui, Xuemei; Rosenbaum, Simon; Firth, Joseph; Richards, Justin; Ward, Philip B; Stubbs, Brendon

    2016-12-01

    Physical activity (PA) is protective from future depression, however, the potential impact of cardiorespiratory fitness (CRF) on the development of depression is less clear. We aimed to investigate if lower levels of CRF are associated with a higher risk for depression onset. Major electronic databases were searched, from inception to January 2016 for prospective cohort studies evaluating the association between CRF and incident depression. Pooled hazard ratio (HR) with 95% confidence intervals (CIs) were calculated. Methodological quality was evaluated using the Newcastle-Ottawa scale (NOS). Three prospective studies were identified and data from two studies were pooled. Our data provide preliminary evidence found that people with low CRF and medium CRF were at increased risk of developing depression (n=1,128,290, HR=1.76, 95% CI 1.61-1.91, p<0.001, I 2 =11.88, and HR=1.23, 95% CI 1.20-1.38, p<0.001, I 2 =0, respectively). Considered alongside the wider benefits of higher levels of CRF, these findings further support the rationale for interventions specifically targeting fitness, in order to reduce the significant burden associated with depression. Copyright © 2016 Elsevier Inc. All rights reserved.

  15. Hopelessness and future thinking in parasuicide: the role of perfectionism.

    PubMed

    Hunter, Elizabeth C; O'Connor, Rory C

    2003-11-01

    This study had three aims: (1) to independently replicate the future thinking effect, that parasuicides, when compared with controls, show a deficit in positive future thinking but no increase in negative future thinking; (2) to determine whether positive future thinking and socially prescribed perfectionism discriminate general hospital parasuicides from controls beyond measures of affect and; (3) to explore the relationship between future thinking and perfectionism. A cross-sectional design was employed. Three groups of participants took part: hospital parasuicide patients (N=22), hospital controls (N=22) and community controls (N=21). Parasuicide patients admitted, via accident and emergency, to a general hospital were matched with hospital and community controls and assessed on measures of hopelessness, depression, anxiety, perfectionism, and future thinking. There was evidence to support the future thinking effect. A discriminant function analysis revealed that social perfectionism and positive future thinking did indeed discriminate parasuicides from controls beyond the effects of hopelessness, depression, and anxiety. Exploratory relationships between perfectionism and positive future thinking were also reported. The results reinforce the importance of future thinking in parasuicide. Moreover, the role of social perfectionism in the suicidal process was elucidated and ought to be replicated within a prospective design.

  16. Can Perceptuo-Motor Skills Assessment Outcomes in Young Table Tennis Players (7–11 years) Predict Future Competition Participation and Performance? An Observational Prospective Study

    PubMed Central

    2016-01-01

    Forecasting future performance in youth table tennis players based on current performance is complex due to, among other things, differences between youth players in growth, development, maturity, context and table tennis experience. Talent development programmes might benefit from an assessment of underlying perceptuo-motor skills for table tennis, which is hypothesized to determine the players’ potential concerning the perceptuo-motor domain. The Dutch perceptuo-motor skills assessment intends to measure the perceptuo-motor potential for table tennis in youth players by assessing the underlying skills crucial for developing technical and tactical qualities. Untrained perceptuo-motor tasks are used as these are suggested to represent a player’s future potential better than specific sport skills themselves as the latter depend on exposure to the sport itself. This study evaluated the value of the perceptuo-motor skills assessment for a talent developmental programme by evaluating its predictive validity for competition participation and performance in 48 young table tennis players (7–11 years). Players were tested on their perceptuo-motor skills once during a regional talent day, and the subsequent competition results were recorded half-yearly over a period of 2.5 years. Logistic regression analysis showed that test scores did not predict future competition participation (p >0.05). Yet, the Generalized Estimating Equations analysis, including the test items ‘aiming at target’, ‘throwing a ball’, and ‘eye-hand coordination’ in the best fitting model, revealed that the outcomes of the perceptuo-motor skills assessment were significant predictors for future competition results (R2 = 51%). Since the test age influences the perceptuo-motor skills assessment’s outcome, another multivariable model was proposed including test age as a covariate (R2 = 53%). This evaluation demonstrates promising prospects for the perceptuo-motor skills assessment to be included in a talent development programme. Future studies are needed to clarify the predictive value in a larger sample of youth competition players over a longer period in time. PMID:26863212

  17. How important is importance for prospective memory? A review

    PubMed Central

    Walter, Stefan; Meier, Beat

    2014-01-01

    Forgetting to carry out an intention as planned can have serious consequences in everyday life. People sometimes even forget intentions that they consider as very important. Here, we review the literature on the impact of importance on prospective memory performance. We highlight different methods used to manipulate the importance of a prospective memory task such as providing rewards, importance relative to other ongoing activities, absolute importance, and providing social motives. Moreover, we address the relationship between importance and other factors known to affect prospective memory and ongoing task performance such as type of prospective memory task (time-, event-, or activity-based), cognitive loads, and processing overlaps. Finally, we provide a connection to motivation, we summarize the effects of task importance and we identify important venues for future research. PMID:25018743

  18. The future(s) of open science.

    PubMed

    Mirowski, Philip

    2018-04-01

    Almost everyone is enthusiastic that 'open science' is the wave of the future. Yet when one looks seriously at the flaws in modern science that the movement proposes to remedy, the prospect for improvement in at least four areas are unimpressive. This suggests that the agenda is effectively to re-engineer science along the lines of platform capitalism, under the misleading banner of opening up science to the masses.

  19. An examination of the prospective impact of bulimic symptoms and dietary restraint on life hassles and social support.

    PubMed

    Kwan, Mun Yee; Gordon, Kathryn H

    2016-02-01

    The stress generation hypothesis posits that individuals with psychopathology engage in maladaptive behaviors that create stress. Although extensively researched in the depression literature, few studies have investigated whether the stress generation hypothesis applies to eating disorders. This study examined whether bulimic symptoms and dietary restraint predict future life hassles and low social support among undergraduate students. Three hundred seventy-four undergraduate students participated in this two-part prospective study through a secure online system. They completed questionnaires assessing depressive symptoms, bulimic symptoms, dietary restraint, life hassles, and social support. Regression analyses revealed that baseline bulimic symptoms predicted greater life hassles but not lower social support one month later, after statistically controlling for baseline measures. Baseline dietary restraint did not predict future life hassles or social support. Limitations include use of self-report measures, suboptimal response rates at the follow-up assessment, and use of a non-clinical sample with primarily White participants. These results provide preliminary support for the stress generation hypothesis in relation to bulimic symptoms. Individuals with bulimic symptoms may generate stressors similar to those experiencing depressive symptoms. Our findings suggest that emphasizing stress management in the treatment of individuals with bulimic symptoms could potentially improve treatment outcomes. Copyright © 2015 Elsevier B.V. All rights reserved.

  20. Idiopathic intracranial hypertension: ongoing clinical challenges and future prospects

    PubMed Central

    Julayanont, Parunyou; Karukote, Amputch; Ruthirago, Doungporn; Panikkath, Deepa; Panikkath, Ragesh

    2016-01-01

    Idiopathic intracranial hypertension (IIH) is an uncommon disorder characterized by increased intracranial pressure without radiological or laboratory evidence of intracranial pathology except empty sella turcica, optic nerve sheath with filled out cerebrospinal fluid spaces, and smooth-walled nonflow-related venous sinus stenosis or collapse. This condition typically affects obese women. The incidence of IIH is increasing with the rising prevalence of obesity. Persistent headache is the most common symptom. Visual impairment is a serious complication that may not be recognized by the patients. This paper reviews clinical manifestations, diagnostic challenges, and current treatments of IIH in adults. Various imaging modalities have been studied on their validity for detection of IIH and papilledema. This review also includes new studies on medical, surgical, and interventional management of this condition. Acetazolamide and topiramate are the only two medications that have been studied in randomized controlled trials about their efficacy in treatment of IIH. In patients who have severe visual impairment or progressive visual deterioration despite medical management, surgical or interventional treatment may be considered. The efficacy and complications of cerebrospinal fluid diversion, optic nerve sheath fenestration, and endovascular venous stenting reported in the last 3 decades have been summarized in this review. Finally, the prospective aspects of biomarkers and treatments are proposed for future research. PMID:26929666

  1. Prospective study of risk factors for suicidal behavior in individuals with anxiety disorders.

    PubMed

    Uebelacker, L A; Weisberg, R; Millman, M; Yen, S; Keller, M

    2013-07-01

    Anxiety disorders are very common and increase risk for suicide attempts. Little is known about predictors of increased risk specifically among individuals with anxiety disorders. The purpose of this study was to investigate whether specific anxiety disorders and other co-morbid psychiatric disorders, physical health, or work or social functioning increased the future likelihood of a suicide attempts among individuals with anxiety disorders. Method In this prospective study, 676 individuals with an anxiety disorder were followed for an average of 12 years. As hypothesized, we found that post-traumatic stress disorder, major depressive disorder (MDD), intermittent depressive disorder (IDD), epilepsy, pain, and poor work and social functioning all predicted a shorter time to a suicide attempt in univariate analyses. In multivariate analyses, baseline MDD and IDD were independent predictors of time to suicide attempt, even when controlling for a past history of suicide attempt. No specific anxiety disorder was an independent predictor of time to attempt in this anxiety-disordered sample. Adding baseline physical health variables and social functioning did not improve the ability of the model to predict time to suicide attempt. Mood disorders and past history of suicide attempts are the most powerful predictors of a future suicide attempt in this sample of individuals, all of whom have an anxiety disorder.

  2. Everolimus as first line therapy for pancreatic neuroendocrine tumours: current knowledge and future perspectives.

    PubMed

    Gallo, Marco; Malandrino, Pasqualino; Fanciulli, Giuseppe; Rota, Francesca; Faggiano, Antongiulio; Colao, Annamaria

    2017-07-01

    Everolimus has been shown to be effective for advanced pancreatic neuroendocrine tumours (pNETs), but its positioning in the therapeutic algorithm for pNETs is matter of debate. With the aim to shed light on this point, we performed an up-to-date critical review taking into account the results of both retrospective and prospective published studies, and the recommendations of international guidelines. In addition, we performed an extensive search on the Clinical Trial Registries databases worldwide, to gather information on the ongoing clinical trials related to this specific topic. We identified eight retrospective published studies, two prospective published studies, and five registered clinical trials. Moreover, we analyzed the content of four widespread international guidelines. Our critical review confirms the lack of high-quality data to recommend everolimus as the first line therapy for pNETs. The ongoing clinical trials reported in this review will hopefully help clinicians, in the near future, to better evaluate the role of everolimus as the first line therapy for pNETs. However, at the moment, there is already enough evidence to recommend everolimus as the first line therapy for patients with symptomatic malignant unresectable insulin-secreting pNETs, to control the endocrine syndrome regardless of tumour growth.

  3. Future risk of labour market marginalization in young suicide attempters--a population-based prospective cohort study.

    PubMed

    Niederkrotenthaler, Thomas; Tinghög, Petter; Alexanderson, Kristina; Dahlin, Marie; Wang, Mo; Beckman, Karin; Gould, Madeleine; Mittendorfer-Rutz, Ellenor

    2014-10-01

    Research on future labour market marginalization following suicide attempt at young age is scarce. We investigated the effects of suicide attempts on three labour market outcomes: unemployment, sickness absence and disability pension. We conducted a prospective cohort study based on register linkage of 1,613,816 individuals who in 1994 were 16-30 years old and lived in Sweden. Suicide attempters treated in inpatient care during the 3 years preceding study entry, i.e. 1992-94 (N=5649) were compared with the general population of the same age without suicide attempt between 1973 and 2010 (n=1,608,167). Hazard ratios (HRs) for long-term unemployment (>180 days), sickness absence (>90 days) and disability pension in 1995-2010 were calculated by Cox regression models, adjusted for a number of parental and individual risk markers, and stratified for previous psychiatric inpatient care not due to suicide attempt. The risks for unemployment [HR 1.58; 95% confidence interval (CI) 1.52-1.64], sickness absence (HR 2.16; 2.08-2.24) and disability pension (HR 4.57; 4.34-4.81) were considerably increased among suicide attempters. There was a dose-response relationship between number of suicide attempts and the risk of disability pension, for individuals both with or without previous psychiatric hospitalizations not due to suicide attempts. No such relationship was present with regard to unemployment. This study highlights the strong association of suicide attempts with future marginalization from the labour market, particularly for outcomes that are based on a medical assessment. Studies that focus only on unemployment may largely underestimate the true detrimental impact of suicide attempt on labour market marginalization. © The Author 2014; all rights reserved. Published by Oxford University Press on behalf of the International Epidemiological Association.

  4. Dealing with Prospective Memory Demands While Performing an Ongoing Task: Shared Processing, Increased On-Task Focus, or Both?

    ERIC Educational Resources Information Center

    Rummel, Jan; Smeekens, Bridget A.; Kane, Michael J.

    2017-01-01

    Prospective memory (PM) is the cognitive ability to remember to fulfill intended action plans at the appropriate future moment. Current theories assume that PM fulfillment draws on attentional processes. Accordingly, pending PM intentions interfere with other ongoing tasks to the extent to which both tasks rely on the same processes. How do people…

  5. Seymour Sarason in Memorial: Prospects for Community and Social Change

    ERIC Educational Resources Information Center

    Maton, Kenneth I.

    2012-01-01

    Seymour Sarason passed away on January 10, 2010 at the age of 91. He was the author of more than 40 books, including The Culture of the School and the Problem of Change (1971), The Creation of Settings and the Future Societies (1972), and The Psychological Sense of Community: Prospects for a Community Psychology (1974). His groundbreaking ideas…

  6. Prospective Memory in an Air Traffic Control Simulation: External Aids that Signal when to Act

    ERIC Educational Resources Information Center

    Loft, Shayne; Smith, Rebekah E.; Bhaskara, Adella

    2011-01-01

    At work and in our personal life we often need to remember to perform intended actions at some point in the future, referred to as Prospective Memory. Individuals sometimes forget to perform intentions in safety-critical work contexts. Holding intentions can also interfere with ongoing tasks. We applied theories and methods from the experimental…

  7. Species Distribution 2.0: An Accurate Time- and Cost-Effective Method of Prospection Using Street View Imagery

    PubMed Central

    Schwoertzig, Eugénie; Millon, Alexandre

    2016-01-01

    Species occurrence data provide crucial information for biodiversity studies in the current context of global environmental changes. Such studies often rely on a limited number of occurrence data collected in the field and on pseudo-absences arbitrarily chosen within the study area, which reduces the value of these studies. To overcome this issue, we propose an alternative method of prospection using geo-located street view imagery (SVI). Following a standardised protocol of virtual prospection using both vertical (aerial photographs) and horizontal (SVI) perceptions, we have surveyed 1097 randomly selected cells across Spain (0.1x0.1 degree, i.e. 20% of Spain) for the presence of Arundo donax L. (Poaceae). In total we have detected A. donax in 345 cells, thus substantially expanding beyond the now two-centuries-old field-derived record, which described A. donax only 216 cells. Among the field occurrence cells, 81.1% were confirmed by SVI prospection to be consistent with species presence. In addition, we recorded, by SVI prospection, 752 absences, i.e. cells where A. donax was considered absent. We have also compared the outcomes of climatic niche modeling based on SVI data against those based on field data. Using generalized linear models fitted with bioclimatic predictors, we have found SVI data to provide far more compelling results in terms of niche modeling than does field data as classically used in SDM. This original, cost- and time-effective method provides the means to accurately locate highly visible taxa, reinforce absence data, and predict species distribution without long and expensive in situ prospection. At this time, the majority of available SVI data is restricted to human-disturbed environments that have road networks. However, SVI is becoming increasingly available in natural areas, which means the technique has considerable potential to become an important factor in future biodiversity studies. PMID:26751565

  8. 48 CFR 3052.209-73 - Limitation of future contracting.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... determined that this acquisition may give rise to a potential organizational conflict of interest. Accordingly, the attention of prospective offerors is invited to FAR Subpart 9.5—Organizational Conflicts of Interest. (b) The nature of this conflict is [describe the conflict]. (c) The restrictions upon future...

  9. Are Learning Organizations Pragmatic?

    ERIC Educational Resources Information Center

    Cavaleri, Steven A.

    2008-01-01

    Purpose: The purpose of this paper is to evaluate the future prospects of the popular concept known as the learning organization; to trace the influence of philosophical pragmatism on the learning organization and to consider its potential impact on the future; and to emphasize how pragmatic theories have shaped the development of Deming's total…

  10. Industry technology assessment of graphite-polymide composite materials. [conferences

    NASA Technical Reports Server (NTRS)

    1975-01-01

    An assessment of the current state of the art and the future prospects for graphite polyimide composite material technology is presented. Presentations and discussions given at a minisymposium of major issues on the present and future use, availability, processing, manufacturing, and testing of graphite polyimide composite materials are summarized.

  11. Achievements in Training of Future Technology Teachers: European Experience

    ERIC Educational Resources Information Center

    Sheludko, Inna

    2015-01-01

    The article discusses the possibilities and prospects of using the experience of training future technology teachers in European countries. Its structure and content in accordance with national traditions and European standards led to the success of the educational components of the European Higher Pedagogical School. This fact encourages local…

  12. U.S. Natural Gas Markets: Mid-Term Prospects for Natural Gas Supply

    EIA Publications

    2001-01-01

    This service report describes the recent behavior of natural gas markets with respect to natural gas prices, their potential future behavior, the potential future supply contribution of liquefied natural gas and increased access to federally restricted resources, and the need for improved natural gas data.

  13. Financial Management of Libraries: Past Trends and Future Prospects.

    ERIC Educational Resources Information Center

    Roberts, Stephen A.

    2003-01-01

    The financial environment within library and information services is reviewed and a structure for financial management is presented based on funding source and level of commercial activity. Objectives for financial management of library and information services is developed and reviewed in light of future trends and stakeholder perspectives.…

  14. Corporate Philanthropy: Philosophy, Management, Trends, Future, Background.

    ERIC Educational Resources Information Center

    Council on Foundations, Inc., Washington, DC.

    Major policy considerations and the management of corporate philanthropy, along with new directions and future prospects of corporate philanthropy, are addressed in 40 articles written by chief executive officers, lawyers, economists, and other leading analysts. In addition, a list of resource materials, a glossary, and a list of organizations…

  15. Post-thrombotic syndrome in children: a systematic review of frequency of occurrence, validity of outcome measures, and prognostic factors

    PubMed Central

    Goldenberg, Neil A.; Donadini, Marco P.; Kahn, Susan R.; Crowther, Mark; Kenet, Gili; Nowak-Göttl, Ulrike; Manco-Johnson, Marilyn J.

    2010-01-01

    Background Post-thrombotic syndrome is a manifestation of chronic venous insufficiency following deep venous thrombosis. This systematic review was conducted to critically evaluate pediatric evidence on frequency of occurrence, validity of outcome measures, and prognostic indicators of post-thrombotic syndrome. Design and Methods A comprehensive literature search of original reports revealed 19 eligible studies, totaling 977 patients with upper/lower extremity deep venous thrombosis. Calculated weighted mean frequency of post-thrombotic syndrome was 26% (95% confidence interval: 23–28%) overall, and differed significantly by prospective/non-prospective analysis and use/non-use of a standardized outcome measure. Results Standardized post-thrombotic syndrome outcome measures included an adaptation of the Villalta scale, the Clinical-Etiologic-Anatomic-Pathologic classification, and the Manco-Johnson instrument. Data on validity were reported only for the Manco-Johnson instrument. No publications on post-thrombotic syndrome-related quality of life outcomes were identified. Candidate prognostic factors for post-thrombotic syndrome in prospective studies included use/non-use of thrombolysis and plasma levels of factor VIII activity and D-dimer. Conclusions Given that affected children must endure chronic sequelae for many decades, it is imperative that future collaborative pediatric prospective cohort studies and trials assess as key objectives and outcomes the incidence, severity, prognostic indicators, and health impact of post-thrombotic syndrome, using validated measures. PMID:20595095

  16. Christodoulou Memory of GW150914 - Prospects of Detection in LIGO and Future Detectors

    NASA Astrophysics Data System (ADS)

    Johnson, Aaron; Kapadia, Shasvath; Kennefick, Daniel

    2017-01-01

    The event GW150914 produced strains of the order 10-21 in the two instruments comprising the Laser Interferometric Gravitational Wave Observatory (LIGO). The event has been interpreted as originating in a coalescing black hole binary, with individual components of about 30 solar masses each. A striking aspect of the coalescence deduced from the signal is the emission of 3 solar masses of energy in the oscillating gravitational wave. Theory predicts a DC component of the gravitational signal associated with the emission of such large amounts of gravitational wave energy known as the Christodoulou memory. The memory, as a non-linear component of the signal, is expected to be an order of magnitude smaller than the amplitude of the primary AC component of the gravitational waves. We discuss the prospects of detecting the Christodoulou memory in similar future signals, both with LIGO and with other detectors, including future space-based instruments.

  17. Time perspective and weight management behaviors in newly diagnosed Type 2 diabetes: a mediational analysis.

    PubMed

    Hall, Peter A; Fong, Geoffrey T; Cheng, Alice Y

    2012-12-01

    The primary objective of the current study was to examine the extent to which domain-specific time perspective predicts weight management behaviors (dietary behavior and physical activity) among those newly diagnosed with Type 2 diabetes. A secondary objective was to test potential mediators of the hypothesized effect (behavioral intention, self-efficacy and control beliefs). A total of 204 adults newly diagnosed (≤6 months) with Type 2 diabetes participated in the study, which included a baseline assessment of domain-general and domain-specific time perspective, as well as strength of intention to perform two weight-management behaviors (dietary choice and physical activity); both weight-management behaviors were assessed again at 6 month follow-up. Hierarchical multiple regression analyses revealed a prospective association between domain-specific time perspective and uptake of weight management behaviors. Individuals with newly diagnosed T2DM possessing a future-oriented time perspective reported making less frequent fatty food choices and greater increases in physical activity over the 6-month follow-up interval. These effects were selectively mediated by intention strength, and not competing social cognitive variables. For both behaviors, the total effects and meditational models were robust to adjustments for demographics, body composition and disease variables. A future-oriented time perspective is prospectively associated with superior uptake of weight management behaviors among those with newly diagnosed Type 2 diabetes. The facilitating effect of future-oriented thinking appears to occur via enhanced strength of intentions to perform weight management behaviors.

  18. Stress, cortisol, and other appetite-related hormones: Prospective prediction of 6-month changes in food cravings and weight.

    PubMed

    Chao, Ariana M; Jastreboff, Ania M; White, Marney A; Grilo, Carlos M; Sinha, Rajita

    2017-04-01

    To examine whether baseline chronic stress, morning cortisol, and other appetite-related hormones (leptin, ghrelin, and insulin) predict future weight gain and food cravings in a naturalistic, longitudinal, 6-month follow-up study. A prospective community cohort of 339 adults (age 29.1 ± 9.0 years; BMI = 26.7 ± 5.4 kg/m 2 ; 56.9% female; 70.2% white) completed assessments at baseline and 6-month follow-up. Fasting blood draws were used to assess cortisol and other appetite-related hormone levels at baseline. At baseline and follow-up, body weight was measured, and the Cumulative Adversity Interview and Food Craving Inventory were administered. Data were analyzed using linear mixed models adjusting for demographic and clinical covariates. Over the 6-month period, 49.9% of the sample gained weight. Food cravings and chronic stress decreased over 6 months (Ps < 0.05). However, after adjusting for covariates, individuals with higher baseline total ghrelin had significantly higher food cravings at 6 months (P = 0.04). Furthermore, higher cortisol, insulin, and chronic stress were each predictive of greater future weight gain (Ps < 0.05). These results suggest that ghrelin plays a role in increased food cravings and reward-driven eating behaviors. Studies are needed that examine the utility of stress reduction methods for normalizing disrupted cortisol responses and preventing future weight gain. © 2017 The Obesity Society.

  19. Stress, cortisol, and other appetite-related hormones: Prospective prediction of 6-month changes in food cravings and weight

    PubMed Central

    Chao, Ariana M.; Jastreboff, Ania M.; White, Marney A.; Grilo, Carlos M.; Sinha, Rajita

    2017-01-01

    Objective To examine whether baseline chronic stress, morning cortisol, and other appetite-related hormones (leptin, ghrelin, and insulin) predict future weight gain and food cravings in a naturalistic longitudinal 6-month follow-up study. Methods A prospective community cohort of three hundred and thirty-nine adults (age=29.1± 9.0 years; BMI=26.7±5.4 kg/m2; 56.9% female; 70.2% White) completed assessments at baseline and 6-month follow-up. Fasting blood draws were used to assess cortisol and other appetite-related hormones levels at baseline. At baseline and follow-up, body weight was measured and the Cumulative Adversity Interview and Food Craving Inventory were administered. Data were analyzed using linear mixed models adjusting for demographic and clinical covariates. Results Over the 6-month period, 49.9% of the sample gained weight. Food cravings and chronic stress decreased over 6 months (ps<0.05). However, after adjusting for covariates, individuals with higher baseline total ghrelin had significantly higher food cravings at 6 months (p=0.04). Furthermore, higher cortisol, insulin, and chronic stress were each predictive of greater future weight gain (ps<0.05). Conclusions These results suggest that ghrelin plays a role in increased food cravings and reward-driven eating behaviors. Studies are needed that examine the utility of stress reduction methods for normalizing disrupted cortisol responses and preventing future weight gain. PMID:28349668

  20. The benefits associated with volunteering among seniors: a critical review and recommendations for future research.

    PubMed

    Anderson, Nicole D; Damianakis, Thecla; Kröger, Edeltraut; Wagner, Laura M; Dawson, Deirdre R; Binns, Malcolm A; Bernstein, Syrelle; Caspi, Eilon; Cook, Suzanne L

    2014-11-01

    There is an urgent need to identify lifestyle activities that reduce functional decline and dementia associated with population aging. The goals of this article are to review critically the evidence on the benefits associated with formal volunteering among older adults, propose a theoretical model of how volunteering may reduce functional limitations and dementia risk, and offer recommendations for future research. Database searches identified 113 papers on volunteering benefits in older adults, of which 73 were included. Data from descriptive, cross-sectional, and prospective cohort studies, along with 1 randomized controlled trial, most consistently reveal that volunteering is associated with reduced symptoms of depression, better self-reported health, fewer functional limitations, and lower mortality. The extant evidence provides the basis for a model proposing that volunteering increases social, physical, and cognitive activity (to varying degrees depending on characteristics of the volunteer placement) which, through biological and psychological mechanisms, leads to improved functioning; we further propose that these volunteering-related functional improvements should be associated with reduced dementia risk. Recommendations for future research are that studies (a) include more objective measures of psychosocial, physical, and cognitive functioning; (b) integrate qualitative and quantitative methods in prospective study designs; (c) explore further individual differences in the benefits associated with volunteering; (d) include occupational analyses of volunteers' specific jobs in order to identify their social, physical, and cognitive complexity; (e) investigate the independent versus interactive health benefits associated with volunteering relative to engagement in other forms of activity; and (f) examine the relationship between volunteering and dementia risk. (PsycINFO Database Record (c) 2014 APA, all rights reserved).

  1. Head Trauma with or without Mild Brain Injury Increases the Risk of Future Traumatic Death: A Controlled Prospective 15-Year Follow-Up Study.

    PubMed

    Vaaramo, Kalle; Puljula, Jussi; Tetri, Sami; Juvela, Seppo; Hillbom, Matti

    2015-10-15

    Patients who have recovered from traumatic brain injury (TBI) show an increased risk of premature death. To investigate long-term mortality rates in a population admitted to the hospital for head injury (HI), we conducted a population-based prospective case-control, record-linkage study, All subjects who were living in Northern Ostrobothnia, and who were admitted to Oulu University Hospital in 1999 because of HI (n=737), and 2196 controls matched by age, gender, and residence randomly drawn from the population of Northern Ostrobothnia were included. Death rate and causes of death in HI subjects during 15 years of follow-up was compared with the general population controls. The crude mortality rates were 56.9, 18.6, and 23.8% for subjects having moderate-to-severe traumatic brain injury (TBI), mild TBI, and head injury without TBI, respectively. The corresponding approximate annual mortality rates were 6.7%, 1.4%, and 1.9%. All types of index HI predicted a significant risk of traumatic death in the future. Subjects who had HI without TBI had an increased risk of both death from all causes (hazard ratio 2.00; 95% confidence interval 1.57-2.55) and intentional or unintentional traumatic death (4.01, 2.20-7.30), compared with controls. The main founding was that even HI without TBI carries an increased risk of future traumatic death. The reason for this remains unknown and further studies are needed. To prevent such premature deaths, post-traumatic therapy should include an interview focusing on lifestyle factors.

  2. Comparison of the Fullerton Advanced Balance Scale, Mini-BESTest, and Berg Balance Scale to Predict Falls in Parkinson Disease.

    PubMed

    Schlenstedt, Christian; Brombacher, Stephanie; Hartwigsen, Gesa; Weisser, Burkhard; Möller, Bettina; Deuschl, Günther

    2016-04-01

    The correct identification of patients with Parkinson disease (PD) at risk for falling is important to initiate appropriate treatment early. This study compared the Fullerton Advanced Balance (FAB) scale with the Mini-Balance Evaluation Systems Test (Mini-BESTest) and Berg Balance Scale (BBS) to identify individuals with PD at risk for falls and to analyze which of the items of the scales best predict future falls. This was a prospective study to assess predictive criterion-related validity. The study was conducted at a university hospital in an urban community. Eighty-five patients with idiopathic PD (Hoehn and Yahr stages: 1-4) participated in the study. Measures were number of falls (assessed prospectively over 6 months), FAB scale, Mini-BESTest, BBS, and Unified Parkinson's Disease Rating Scale. The FAB scale, Mini-BESTest, and BBS showed similar accuracy to predict future falls, with values for area under the curve (AUC) of the receiver operating characteristic (ROC) curve of 0.68, 0.65, and 0.69, respectively. A model combining the items "tandem stance," "rise to toes," "one-leg stance," "compensatory stepping backward," "turning," and "placing alternate foot on stool" had an AUC of 0.84 of the ROC curve. There was a dropout rate of 19/85 participants. The FAB scale, Mini-BESTest, and BBS provide moderate capacity to predict "fallers" (people with one or more falls) from "nonfallers." Only some items of the 3 scales contribute to the detection of future falls. Clinicians should particularly focus on the item "tandem stance" along with the items "one-leg stance," "rise to toes," "compensatory stepping backward," "turning 360°," and "placing foot on stool" when analyzing postural control deficits related to fall risk. Future research should analyze whether balance training including the aforementioned items is effective in reducing fall risk. © 2016 American Physical Therapy Association.

  3. The Danish Testicular Cancer database.

    PubMed

    Daugaard, Gedske; Kier, Maria Gry Gundgaard; Bandak, Mikkel; Mortensen, Mette Saksø; Larsson, Heidi; Søgaard, Mette; Toft, Birgitte Groenkaer; Engvad, Birte; Agerbæk, Mads; Holm, Niels Vilstrup; Lauritsen, Jakob

    2016-01-01

    The nationwide Danish Testicular Cancer database consists of a retrospective research database (DaTeCa database) and a prospective clinical database (Danish Multidisciplinary Cancer Group [DMCG] DaTeCa database). The aim is to improve the quality of care for patients with testicular cancer (TC) in Denmark, that is, by identifying risk factors for relapse, toxicity related to treatment, and focusing on late effects. All Danish male patients with a histologically verified germ cell cancer diagnosis in the Danish Pathology Registry are included in the DaTeCa databases. Data collection has been performed from 1984 to 2007 and from 2013 onward, respectively. The retrospective DaTeCa database contains detailed information with more than 300 variables related to histology, stage, treatment, relapses, pathology, tumor markers, kidney function, lung function, etc. A questionnaire related to late effects has been conducted, which includes questions regarding social relationships, life situation, general health status, family background, diseases, symptoms, use of medication, marital status, psychosocial issues, fertility, and sexuality. TC survivors alive on October 2014 were invited to fill in this questionnaire including 160 validated questions. Collection of questionnaires is still ongoing. A biobank including blood/sputum samples for future genetic analyses has been established. Both samples related to DaTeCa and DMCG DaTeCa database are included. The prospective DMCG DaTeCa database includes variables regarding histology, stage, prognostic group, and treatment. The DMCG DaTeCa database has existed since 2013 and is a young clinical database. It is necessary to extend the data collection in the prospective database in order to answer quality-related questions. Data from the retrospective database will be added to the prospective data. This will result in a large and very comprehensive database for future studies on TC patients.

  4. From Present Surveying to Future Prospecting of the Asteroid Belt

    NASA Technical Reports Server (NTRS)

    Clark, P. E.; Curtis, S. A.; Rilee, M.; Cheung, C.

    2004-01-01

    We have applied a future mission architecture, the Autonomous Nano-Technology Swarm (ANTS), to a proposed mission for in situ survey, or prospecting, of the asteroid belt, the Prospecting Asteroid Mission (PAM) as part of a NASA 2003 Revolutionary Aerospace Concept (RASC) study. ANTS architecture builds on and advances recent trends in robotics, artificial intelligence, and materials processing to minimize costs and maximize effectiveness of space operations. PAM and other applications have been proposed for the survey of inaccessible, high surface area populations of great interest from the standpoint of resources and/or solar system origin. The ANTS architecture is inspired by the success of social insect colonies, a success based on the division of labor within the colonies in two key ways: 1) within their specialties, individual specialists generally outperform generalists, and 2) with sufficiently efficient social interaction and coordination, the group of specialists generally outperforms the group of generalists. Thus systems designed as ANTS are built from potentially very large numbers of highly autonomous, yet socially interactive, elements. The architecture is self-similar in that elements and sub-elements of the system may also be recursively structured as ANTS on scales ranging from microscopic to interplanetary distances. Here, we analyze requirements for the mission application at the low gravity target end of the spectrum, the Prospecting Asteroid Mission (PAM), and for specialized autonomous operations which would support this mission. ANTS as applied to PAM involves the activities of hundreds of individual specialist 'sciencecraft'. Most of them, called Workers, carry and operate eight to nine different scientific instruments, as listed in the table, including spectrometers, ranging and radio science devices, and imagers. The remaining specialists, Messenger/Rulers, provide communication and coordination functions among specialists operating autonomously as individuals, team members, and subswarms.

  5. Potential Psychosocial Risk Factors for Chronic TMD: Descriptive Data and Empirically Identified Domains from the OPPERA Case-Control Study

    PubMed Central

    Fillingim, Roger B.; Ohrbach, Richard; Greenspan, Joel D.; Knott, Charles; Dubner, Ronald; Bair, Eric; Baraian, Cristina; Slade, Gary D.; Maixner, William

    2011-01-01

    Case-control studies have consistently associated psychosocial factors with chronic pain in general, and with temporomandibular disorders (TMD) specifically. Moreover, a handful of prospective studies suggest that pre-existing psychosocial characteristics represent risk factors for new onset TMD. The current study presents psychosocial findings from the baseline case-control study of the Orofacial Pain Prospective Evaluation and Risk Assessment (OPPERA) cooperative agreement. For this study, 1,633 TMD-free controls and 185 TMD cases completed a battery of psychosocial instruments assessing general psychosocial adjustment and personality, affective distress, psychosocial stress, somatic awareness, and pain coping and catastrophizing. In bivariate and demographically-adjusted analyses, odds of TMD were associated with higher levels of psychosocial symptoms, affective distress, somatic awareness, and pain catastrophizing. Among controls, significant gender and ethnic group differences in psychosocial measures were observed, consistent with previous findings. Principal component analysis was undertaken to identify latent constructs revealing four components: stress and negative affectivity, global psychosocial symptoms, passive pain coping, and active pain coping. These findings provide further evidence of associations between psychosocial factors and TMD. Future prospective analyses in the OPPERA cohort will determine if the premorbid presence of these psychosocial factors predicts increased risk for developing new-onset TMD. PMID:22074752

  6. Concurrent and prospective associations between facial affect recognition accuracy and childhood antisocial behavior.

    PubMed

    Bowen, Erica; Dixon, Louise

    2010-01-01

    This study examined the concurrent and prospective associations between children's ability to accurately recognize facial affect at age 8.5 and antisocial behavior at age 8.5 and 10.5 years in a sub sample of the Avon Longitudinal Study of Parents and Children cohort (5,396 children; 2,644, 49% males). All observed effects were small. It was found that at age 8.5 years, in contrast to nonantisocial children; antisocial children were less accurate at decoding happy and sad expressions when presented at low intensity. In addition, concurrent antisocial behavior was associated with misidentifying expressions of fear as expressions of sadness. In longitudinal analyses, children who misidentified fear as anger exhibited a decreased risk of antisocial behavior 2 years later. The study suggests that concurrent rather than future antisocial behavior is associated with facial affect recognition accuracy. (c) 2010 Wiley-Liss, Inc.

  7. Cultural psychiatry: research strategies and future directions.

    PubMed

    Kirmayer, Laurence J; Ban, Lauren

    2013-01-01

    This chapter reviews some key aspects of current research in cultural psychiatry and explores future prospects. The first section discusses the multiple meanings of culture in the contemporary world and their relevance for understanding mental health and illness. The next section considers methodological strategies for unpacking the concept of culture and studying the impact of cultural variables, processes and contexts. Multiple methods are needed to address the many different components or dimensions of cultural identity and experience that constitute local worlds, ways of life or systems of knowledge. Quantitative and observational methods of clinical epidemiology and experimental science as well as qualitative ethnographic methods are needed to capture crucial aspects of culture as systems of meaning and practice. Emerging issues in cultural psychiatric research include: cultural variations in illness experience and expression; the situated nature of cognition and emotion; cultural configurations of self and personhood; concepts of mental disorder and mental health literacy; and the prospect of ecosocial models of health and culturally based interventions. The conclusion considers the implications of the emerging perspectives from cultural neuroscience for psychiatric theory and practice. Copyright © 2013 S. Karger AG, Basel.

  8. Current status and future prospects of hyperthermic intraoperative intraperitoneal chemotherapy (HIPEC) clinical trials in ovarian cancer.

    PubMed

    Cowan, Renee A; O'Cearbhaill, Roisin E; Zivanovic, Oliver; Chi, Dennis S

    2017-08-01

    The natural history of advanced-stage epithelial ovarian cancer is one of clinical remission after surgery and platinum/taxane-based intravenous (IV) and/or intraperitoneal (IP) chemotherapy followed by early or late recurrence in the majority of patients. Prevention of progression and recurrence remains a major hurdle in the management of ovarian cancer. Recently, many investigators have evaluated the use of normothermic and hyperthermic intraoperative IP drug delivery as a management strategy. This is a narrative review of the current status of clinical trials of hyperthermic intraoperative intraperitoneal chemotherapy (HIPEC) in ovarian cancer and the future directions for this treatment strategy. The existing studies on HIPEC in patients with epithelial ovarian cancer are mostly retrospective in nature, are heterogeneous with regards to combined inclusion of primary and recurrent disease and lack unbiased data. Until data are available from evidence-based trials, it is reasonable to conclude that surgical cytoreduction and HIPEC is a rational and interesting, though still investigative, approach in the management of epithelial ovarian cancer, whose use should be employed within prospective clinical trials.

  9. Present and future prospects of accelerator mass spectrometry

    NASA Astrophysics Data System (ADS)

    Kutschera, Walter

    1988-05-01

    Accelerator mass spectrometry (AMS) has become a powerful technique for measuring extremely low abundances (10 -10 to 10 -15 relative to stable isotopes) of long-lived radioisotopes with half-lives in the range from 10 2 to 10 8 years. With a few exceptions, tandem accelerators turned out to be the most useful instruments for AMS measurements. Both natural (mostly cosmogenic) and manmade (anthropogenic) radioisotopes are studied with this technique. In some cases very low concentrations of stable isotopes are also measured. Applications of AMS cover a large variety of fields including anthropology, archaeology, oceanography, hydrology, climatology, volcanology, mineral exploration, cosmochemistry, meteoritics, glaciology, sedimentary processes, geochronology, environmental physics, astrophysics, nuclear and particle physics. Present and future prospects of AMS will be discussed as an interplay between the continuous development of new techniques and the investigation of problems in the above mentioned fields. Depending on the specific problem to be investigated, different aspects of an AMS system are of importance. Typical factors to be considered are energy range and type of accelerator, and the possibilities of dedicated versus partial use of new or existing accelerators.

  10. Ultrasonic High-Temperature Sensors: Past Experiments and Prospects for Future Use

    NASA Astrophysics Data System (ADS)

    Laurie, M.; Magallon, D.; Rempe, J.; Wilkins, C.; Pierre, J.; Marquié, C.; Eymery, S.; Morice, R.

    2010-09-01

    Ultrasonic thermometry sensors (UTS) have been intensively studied in the past to measure temperatures from 2080 K to 3380 K. This sensor, which uses the temperature dependence of the acoustic velocity in materials, was developed for experiments in extreme environments. Its major advantages, which are (a) capability of measuring a temperature profile from multiple sensors on a single probe and (b) measurement near the sensor material melting point, can be of great interest when dealing with on-line monitoring of high-temperature safety tests. Ultrasonic techniques were successfully applied in several severe accident related experiments. With new developments of alternative materials, this instrument may be used in a wide range of experimental areas where robustness and compactness are required. Long-term irradiation experiments of nuclear fuel to extremely high burn-ups could benefit from this previous experience. After an overview of UTS technology, this article summarizes experimental work performed to improve the reliability of these sensors. The various designs, advantages, and drawbacks are outlined and future prospects for long-term high-temperature irradiation experiments are discussed.

  11. Teaching and Learning Tibetan: The Role of the Tibetan Language in Tibet's Future. Roundtable before the Congressional-Executive Commission on China. One Hundred Eighth Congress, First Session (April 7, 2003).

    ERIC Educational Resources Information Center

    2003

    This roundtable focused on issues related to the role of the Tibetan language in Tibet's future. A statement by Nicolas Tournadre, Associate Professor of Linguistics, the University of Paris, France, addresses "The Dynamics of Tibetan-Chinese Bilingualism: The Current Situation and Future Prospects" (e.g., the first regulation protecting…

  12. Prospective Assessment of Neurocognition in Future Gulf-deployed and Gulf-nondeployed Military Personnel: A Pilot Study

    DTIC Science & Technology

    2007-02-01

    increased emotional distress but with advantaged simple reactiontime. Unit cohesion buffers the adverse effects of early life events on PTSD prior to...motor speed), and emotional (e.g., mood) behaviors thought to reflect neural integrity. Unresolved issues include whether subjective...including neurobehavioral and emotional functioning, (b) examine the impact of deployment-related stress and environmental exposures on

  13. Life on ice, Antarctica and Mars

    NASA Technical Reports Server (NTRS)

    Anderson, D. T.; Mckay, C. P.; Wharton, Robert A., Jr.; Sagan, C.; Squyres, S. W.; Simmons, G. M.

    1991-01-01

    The study of the origin of life and the prospects for human exploration of Mars are two themes developed in a new 57-minute film, Life on Ice, Antarctica, and Mars, produced by the InnerSpace Foundation and WHRO Television for broadcast by the Public Broadcasting System (PBS). A brief explanation of the film and how it relates to the future human exploration of space is presented.

  14. Training Implications of Technological Change in Manufacturing in New Industrial Countries: The Case of Yugoslavia. Training Policies Discussion Paper No. 15.

    ERIC Educational Resources Information Center

    Matejic, Vlastimir; Kamhi, Meri

    This report is a study of the training implications of technological change in manufacturing in Yugoslavia. Part 1 analyzes the general technological and educational infrastructure in Yugoslavia. The sources of technology as well as the present state and future prospects of technological research are described. Education is discussed in terms of…

  15. Educational Technology Program for Nova Scotia: Initial Phase. A Report on the Federal-Provincial Study of Educational Technology in Nova Scotia.

    ERIC Educational Resources Information Center

    deVille, Barry, Ed.

    This is a preliminary examination of the present status and future prospects of educational technology in Nova Scotian schools. It is aimed at developing a plan to enhance the quality of educational technology by concentrating on systems which will be conducive to realizing educational goals at a reasonable cost. An overview of the institutional…

  16. Technological advances in radiotherapy of rectal cancer: opportunities and challenges.

    PubMed

    Appelt, Ane L; Sebag-Montefiore, David

    2016-07-01

    This review summarizes the available evidence for the use of modern radiotherapy techniques for chemoradiotherapy for rectal cancer, with specific focus on intensity-modulated radiotherapy (IMRT) and volumetric arc therapy (VMAT) techniques. The dosimetric benefits of IMRT and VMAT are well established, but prospective clinical studies are limited, with phase I-II studies only. Recent years have seen the publication of a few larger prospective patient series as well as some retrospective cohorts, several of which include much needed late toxicity data. Overall results are encouraging, as toxicity levels - although varying across reports - appear lower than for 3D conformal radiotherapy. Innovative treatment techniques and strategies which may be facilitated by the use of IMRT/VMAT include simultaneously integrated tumour boost, adaptive treatment, selective sparing of specific organs to enable chemotherapy escalation, and nonsurgical management. Few prospective studies of IMRT and VMAT exist, which causes uncertainty not just in regards to the clinical benefit of these technologies but also in the optimal use. The priority for future research should be subgroups of patients who might receive relatively greater benefit from innovative treatment techniques, such as patients receiving chemoradiotherapy with definitive intent and patients treated with dose escalation.

  17. Present Status and Future Prospects in Bulk Processing of HIGH-Tc Superconductors

    NASA Astrophysics Data System (ADS)

    Jin, S.; Chu, C. W.

    The following sections are included: * INTRODUCTION * HIGH SUPERCONDUCTING TRANSITION TEMPERATURE * HIGH CRITICAL CURRENT DENSITY * Grain Boundary Weak Links * Nature of Weak Links * Possible Processing Approaches for Weak Link Problem * Processing Techniques for Texture Formation * Flux Creep in HTSC * Desirable Pinning Defects * Processing for Flux Pinning Enhancement * PROSPECTS FOR BULK APPLICATIONS * Magnetic Field Gener * Energy Storage * Magnetic Shielding * Other Applications * CONCLUDING REMARKS * ACKNOWLEDGMENT * REFERENCES

  18. Adaptive Automation and Cue Invocation: The Effect of Cue Timing on Operator Error

    DTIC Science & Technology

    2013-05-01

    129. 5. Parasuraman, R. (2000). Designing automation for human use: Empirical studies and quantitative models. Ergonomics , 43, 931-951. 6...Prospective memory errors involve memory for intended actions that are planned to be performed at some designated point in the future [20]. In the DMOO...RESCHU) [21] was used in this study. A Navy pilot who is familiar with supervisory control tasks designed the RESCHU task and the task has been

  19. Sleep duration and cardiometabolic risk: a review of the epidemiologic evidence.

    PubMed

    Knutson, Kristen L

    2010-10-01

    Laboratory studies have found that short-term sleep restriction is associated with impairments in glucose metabolism, appetite regulation and blood pressure regulation. This chapter reviews the epidemiologic evidence for an association between habitual sleep duration and quality and risk of cardiometabolic diseases including obesity, diabetes and hypertension. Multiple studies observed a cross-sectional association between short sleep duration (generally <6 h per night) and increased body mass index or obesity, prevalent diabetes and prevalent hypertension. Many studies also reported an association between self-reported long sleep duration (generally >8 h per night) and cardiometabolic disease. There have been a few prospective studies and several, but not all, have found an association between short sleep and incident diabetes, hypertension and markers of cardiovascular disease. Future prospective epidemiologic studies need to include objective measures of sleep, and intervention studies are needed in order to establish a causal link between impaired or insufficient sleep and cardiometabolic disease risk. Copyright © 2010 Elsevier Ltd. All rights reserved.

  20. Prospective associations between adolescent mental health problems and positive mental wellbeing in early old age.

    PubMed

    Nishida, Atsushi; Richards, Marcus; Stafford, Mai

    2016-01-01

    Mental health problems in adolescence are predictive of future mental distress and psychopathology; however, few studies investigated adolescent mental health problems in relation to future mental wellbeing and none with follow-up to older age. To test prospective associations between adolescent mental health problems and mental wellbeing and life satisfaction in early old age. A total of 1561 men and women were drawn from the Medical Research Council National Survey of Health and Development (the British 1946 birth cohort). Teachers had previously completed rating scales to assess emotional adjustment and behaviours, which allowed us to extract factors of mental health problems measuring self-organisation, behavioural problems, and emotional problems during adolescence. Between the ages of 60-64 years, mental wellbeing was assessed using the Warwick-Edinburgh Mental Well-being Scale (WEMWBS) and life satisfaction was self-reported using the Satisfaction with Life Scale (SWLS). After controlling for gender, social class of origin, childhood cognitive ability, and educational attainment, adolescent emotional problems were independently inversely associated with mental wellbeing and with life satisfaction. Symptoms of anxiety/depression at 60-64 years explained the association with life satisfaction but not with mental wellbeing. Associations between adolescent self-organisation and conduct problems and mental wellbeing and life satisfaction were of negligible magnitude, but higher childhood cognitive ability significantly predicted poor life satisfaction in early old age. Adolescent self-organisation and conduct problems may not be predictive of future mental wellbeing and life satisfaction. Adolescent emotional problems may be inversely associated with future wellbeing, and may be associated with lower levels of future life satisfaction through symptoms of anxiety/depression in early old age. Initiatives to prevent and treat emotional problems in adolescence may have long-term benefits which extend into older age.

  1. Evidence for prospective associations among depression and obesity in population-based studies.

    PubMed

    Faith, M S; Butryn, M; Wadden, T A; Fabricatore, A; Nguyen, A M; Heymsfield, S B

    2011-05-01

    Obesity may lead to depression or be one of its consequences. We reviewed population-based studies in order to, first, identify the most commonly used research methods, and, second, to evaluate the strength of evidence for prospective associations among obesity and depression. We examined 25 studies, of which 10 tested 'obesity-to-depression' pathways, and 15 tested 'depression-to-obesity' pathways. Descriptive statistics summarized the frequency with which various measurements, designs and data analytic strategies were used. We tallied the number of studies that reported any vs. no statistically significant associations, and report on effect sizes, identified moderating variables within reports, and sought common findings across studies. Results indicated considerable methodological heterogeneity in the literature. Depression was assessed by clinical interview in 44% of studies, weight and height were directly measured in 32%, and only 12% used both. In total, 80% of the studies reported significant obesity-to-depression associations, with odds ratios generally in the range of 1.0 to 2.0, while only 53% of the studies reported significant depression-to-obesity associations. Sex was a common moderating variable. Thus, there was good evidence that obesity is prospectively associated with increased depression, with less consistent evidence that depression leads to obesity. Recommendations for future research regarding study samples, measurement and data analysis are provided. © 2011 The Authors. obesity reviews © 2011 International Association for the Study of Obesity.

  2. A Review of Clinical Trials in Spinal Cord Injury including Biomarkers.

    PubMed

    Badhiwala, Jetan H; Wilson, Jefferson R; Kwon, Brian K; Casha, Steve; Fehlings, Michael G

    2018-06-11

    Acute traumatic spinal cord injury (SCI) entered the arena of prospective randomized clinical trials almost 40 years ago, with the undertaking of the National Acute Spinal Cord Study (NASCIS) I trial. Since then, a number of clinical trials have been conducted in the field, spurred by the devastating physical, social, and economic consequences of acute SCI for patients, families, and society at large. Many of these have been controversial and attracted criticism. The current review provides a critical summary of select past and current clinical trials in SCI, focusing in particular on the findings of prospective randomized controlled trials (RCTs), the challenges and barriers encountered, and the valuable lessons learned that can be applied to future trials.

  3. Pharmacotherapy for childhood obesity: present and future prospects

    PubMed Central

    Sherafat-Kazemzadeh, Roya; Yanovski, Susan Z.; Yanovski, Jack A.

    2012-01-01

    Pediatric obesity is a serious medical condition associated with significant comorbidities during childhood and adulthood. Lifestyle modifications are essential for treating children with obesity, yet many have insufficient response to improve health with behavioral approaches alone. This review summarizes the relatively sparse data on pharmacotherapy for pediatric obesity and presents information on obesity medications in development. Most previously studied medications demonstrated, at best, modest effects on body weight and obesity-related conditions. It is to be hoped that the future will bring new drugs targeting specific obesity phenotypes that will allow clinicians to use etiology-specific, and therefore more effective, anti-obesity therapies. PMID:22929210

  4. Analysis of Fluctuating Friction Version in Sheet Metallic Designing

    NASA Astrophysics Data System (ADS)

    Ambarayil Joy, Jithin; Jung, Dong Won

    2018-02-01

    Conservative Coulomb method indicates steady constant of rub in thin metal panel making that appears or feels close to the real thing. It contributes to describing attainable future event too high shear pressure in making ahead in the position of high R-value steel (AHRS). The study is conducted by pretend the making and spring back of a specific panel to understand the characteristic of the stamping procedure. Corresponding of the describe probable future results with (i) physical force-dependent changeable rub method, (ii) perpetual rub method, and the conclusion of exploratory facts point out a significant upgrading of spring back forecast with the prospective method.

  5. King’s College London, a cardiac centre of excellence: will it only be possible to deliver the best cardiovascular medicine in 'capital cities' in the future?

    PubMed

    2011-09-01

    New developments at King's College, London, suggest that the complexity of modern cardiovascular medicine, and the enormous prospects for future advances, means that smaller cities will find it hard to compete, reports Barry Shurlock, MA, PhD.

  6. Business Education in Asia and Australasia: Recent Trends and Future Prospects

    ERIC Educational Resources Information Center

    Kearney, Colm

    2013-01-01

    The globalization of business education is leading to convergence in the traditionally more diverse business curriculum. This can be seen by examining the mission and vision statements of Asia and Australasia's leading business schools, which emphasize the provision of quality learning and scholarship; educating future leaders; and contributing to…

  7. Their Future Is Now... Today Is for Children.

    ERIC Educational Resources Information Center

    Dittmann, Laura L., Ed.; Ramsey, Marjorie E., Ed.

    Six very different articles focusing on the prospects of today's youth upon reaching adulthood have been assembled in this booklet. The introductory chapter surveys the articles, with special attention given to technology's effects on life and education both now and in the future. The first article points out changes, good and bad, that will…

  8. Special Education Policy: A Retrospective and Future Prospective--A View from Saskatchewan.

    ERIC Educational Resources Information Center

    Dahl, Harry; Sanche, Robert

    This paper reviews the history of special education in Saskatchewan (Canada) since the 1960s and proposes policy initiatives for future changes. Emphasis in the discussion is on trends and Canadian reports that led to Saskatchewan's 1971 passing of legislation mandating an "appropriate" free public education with procedural due process,…

  9. Assessing present and future capital expense levels under PPS.

    PubMed

    Cleverley, W O

    1986-09-01

    The expected shift in the method of payment for capital costs will affect the way decisions are made by hospital executives. The capital expense ratio model is one way executives can better assess their present and future capital expense levels as payments begin to be made under a prospective payment system.

  10. 24 CFR 17.74 - Standards for suspension or termination of collection action.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... termination of collection action. 17.74 Section 17.74 Housing and Urban Development Office of the Secretary... payment on the Department's claim or effect a compromise, but his future prospects justify retention of... or started anew or (2) future collection can be effected by offset notwithstanding the statute of...

  11. Embracing the Future: What Can Accounting Graduates Expect?

    ERIC Educational Resources Information Center

    Corkern, Sheree M.; Parks, Sandra B.; Morgan, Mark I.

    2013-01-01

    This article informs accounting educators and graduates about key issues in the accounting profession of today, which has entered a new age, and accounting educators and advisors, old and new, must be informed about future prospects for students and make students aware of what they can expect as accounting graduates. Passing this knowledge to…

  12. Which Factors Affect Entrepreneurial Intention of University Students?

    ERIC Educational Resources Information Center

    Turker, Duygu; Selcuk, Senem Sonmez

    2009-01-01

    Purpose: Fostering entrepreneurship needs a twofold policy that should focus on both the current situation and future prospect of entrepreneurship. Although many scholars and policy makers devote their attention to the first foci of issue, it is equally important to map out the future context of entrepreneurship. The purpose of this paper is to…

  13. Exposing the dark sector with future Z factories

    NASA Astrophysics Data System (ADS)

    Liu, Jia; Wang, Lian-Tao; Wang, Xiao-Ping; Xue, Wei

    2018-05-01

    We investigate the prospects of searching dark sector models via exotic Z -boson decay at future e+e- colliders with Giga Z and Tera Z options. Four general categories of dark sector models, Higgs portal dark matter, vector-portal dark matter, inelastic dark matter, and axionlike particles, are considered. Focusing on channels motivated by the dark sector models, we carry out a model-independent study of the sensitivities of Z factories in probing exotic decays. The limits on branching ratios of the exotic Z decay are typically O (10-6- 10-8.5) for the Giga Z and O (10-7.5- 10-11) for the Tera Z , and they are compared with the projection for the high luminosity LHC. We demonstrate that future Z factories can provide its unique and leading sensitivity and highlight the complementarity with other experiments, including the indirect and direct dark matter search limits and the existing collider limits. Future Z factories will play a leading role in uncovering the hidden sector of the Universe in the future.

  14. Projecting Electricity Demand in 2050

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hostick, Donna J.; Belzer, David B.; Hadley, Stanton W.

    2014-07-01

    This paper describes the development of end-use electricity projections and load curves that were developed for the Renewable Electricity (RE) Futures Study (hereafter RE Futures), which explored the prospect of higher percentages (30% - 90%) of total electricity generation that could be supplied by renewable sources in the United States. As input to RE Futures, two projections of electricity demand were produced representing reasonable upper and lower bounds of electricity demand out to 2050. The electric sector models used in RE Futures required underlying load profiles, so RE Futures also produced load profile data in two formats: 8760 hourly datamore » for the year 2050 for the GridView model, and in 2-year increments for 17 time slices as input to the Regional Energy Deployment System (ReEDS) model. The process for developing demand projections and load profiles involved three steps: discussion regarding the scenario approach and general assumptions, literature reviews to determine readily available data, and development of the demand curves and load profiles.« less

  15. Prospective memory in an air traffic control simulation: External aids that signal when to act

    PubMed Central

    Loft, Shayne; Smith, Rebekah E.; Bhaskara, Adella

    2011-01-01

    At work and in our personal life we often need to remember to perform intended actions at some point in the future, referred to as Prospective Memory. Individuals sometimes forget to perform intentions in safety-critical work contexts. Holding intentions can also interfere with ongoing tasks. We applied theories and methods from the experimental literature to test the effectiveness of external aids in reducing prospective memory error and costs to ongoing tasks in an air traffic control simulation. Participants were trained to accept and hand-off aircraft, and to detect aircraft conflicts. For the prospective memory task participants were required to substitute alternative actions for routine actions when accepting target aircraft. Across two experiments, external display aids were provided that presented the details of target aircraft and associated intended actions. We predicted that aids would only be effective if they provided information that was diagnostic of target occurrence and in this study we examined the utility of aids that directly cued participants when to allocate attention to the prospective memory task. When aids were set to flash when the prospective memory target aircraft needed to be accepted, prospective memory error and costs to ongoing tasks of aircraft acceptance and conflict detection were reduced. In contrast, aids that did not alert participants specifically when the target aircraft were present provided no advantage compared to when no aids we used. These findings have practical implications for the potential relative utility of automated external aids for occupations where individuals monitor multi-item dynamic displays. PMID:21443381

  16. Prospective memory in an air traffic control simulation: external aids that signal when to act.

    PubMed

    Loft, Shayne; Smith, Rebekah E; Bhaskara, Adella

    2011-03-01

    At work and in our personal life we often need to remember to perform intended actions at some point in the future, referred to as Prospective Memory. Individuals sometimes forget to perform intentions in safety-critical work contexts. Holding intentions can also interfere with ongoing tasks. We applied theories and methods from the experimental literature to test the effectiveness of external aids in reducing prospective memory error and costs to ongoing tasks in an air traffic control simulation. Participants were trained to accept and hand-off aircraft and to detect aircraft conflicts. For the prospective memory task, participants were required to substitute alternative actions for routine actions when accepting target aircraft. Across two experiments, external display aids were provided that presented the details of target aircraft and associated intended actions. We predicted that aids would only be effective if they provided information that was diagnostic of target occurrence, and in this study, we examined the utility of aids that directly cued participants when to allocate attention to the prospective memory task. When aids were set to flash when the prospective memory target aircraft needed to be accepted, prospective memory error and costs to ongoing tasks of aircraft acceptance and conflict detection were reduced. In contrast, aids that did not alert participants specifically when the target aircraft were present provided no advantage compared to when no aids were used. These findings have practical implications for the potential relative utility of automated external aids for occupations where individuals monitor multi-item dynamic displays.

  17. Optimism and well-being: a prospective multi-method and multi-dimensional examination of optimism as a resilience factor following the occurrence of stressful life events.

    PubMed

    Kleiman, Evan M; Chiara, Alexandra M; Liu, Richard T; Jager-Hyman, Shari G; Choi, Jimmy Y; Alloy, Lauren B

    2017-02-01

    Optimism has been conceptualised variously as positive expectations (PE) for the future , optimistic attributions , illusion of control , and self-enhancing biases. Relatively little research has examined these multiple dimensions of optimism in relation to psychological and physical health. The current study assessed the multi-dimensional nature of optimism within a prospective vulnerability-stress framework. Initial principal component analyses revealed the following dimensions: PEs, Inferential Style (IS), Sense of Invulnerability (SI), and Overconfidence (O). Prospective follow-up analyses demonstrated that PE was associated with fewer depressive episodes and moderated the effect of stressful life events on depressive symptoms. SI also moderated the effect of life stress on anxiety symptoms. Generally, our findings indicated that optimism is a multifaceted construct and not all forms of optimism have the same effects on well-being. Specifically, our findings indicted that PE may be the most relevant to depression, whereas SI may be the most relevant to anxiety.

  18. InternationaL cross-sectIonAl and longItudinal assessment on aSthma cONtrol in European adult patients - the LIAISON study protocol

    PubMed Central

    2013-01-01

    Background According to international guidelines, the goal of asthma management is to achieve and maintain control of the disease, which can be assessed using composite measures. Prospective studies are required to determine how these measures are associated with asthma outcomes and/or future risk. The ‘InternationaL cross-sectIonAl and longItudinal assessment on aSthma cONtrol (LIAISON)’ observational study has been designed to evaluate asthma control and its determinants, including components of asthma management. Methods/design The LIAISON study will be conducted in 12 European countries and comprises a cross-sectional phase and a 12-month prospective phase. Both phases will aim at assessing asthma control (six-item Asthma Control Questionnaire, ACQ), asthma-related quality of life (Mini Asthma Quality of Life Questionnaire, Mini-AQLQ), risk of non-adherence to treatment (four-item Morisky Medication Adherence Scale, MMAS-4), potential reasons for poor control, treatment strategies and associated healthcare costs. The cross-sectional phase will recruit > 8,000 adult patients diagnosed with asthma for at least 6 months and receiving the same asthma treatment in the 4 weeks before enrolment. The prospective phase will include all patients with uncontrolled/poorly controlled asthma at the initial visit to assess the proportion reaching control during follow-up and to examine predictors of future risk. Visits will take place after 3, 6 and 12 months. Discussion The LIAISON study will provide important information on the prevalence of asthma control and on the quality of life in a broad spectrum of real-life patient populations from different European countries and will also contribute to evaluate differences in management strategies and their impact on healthcare costs over 12 months of observation. Trial registration ClinicalTrials.gov identifier, NCT01567280. PMID:23530817

  19. The early growth and development study: a prospective adoption design.

    PubMed

    Leve, Leslie D; Neiderhiser, Jenae M; Ge, Xiaojia; Scaramella, Laura V; Conger, Rand D; Reid, John B; Shaw, Daniel S; Reiss, David

    2007-02-01

    The Early Growth and Development Study is a prospective adoption study of birth parents, adoptive parents, and adopted children (N=359 triads) that was initiated in 2003. The primary study aims are to examine how family processes mediate or moderate the expression of genetic influences in order to aid in the identification of specific family processes that could serve as malleable targets for intervention. Participants in the study are recruited through adoption agencies located throughout the United States, following the birth of a child. Assessments occur at 6-month intervals until the child reaches 3 years of age. Data collection includes the following primary constructs: infant and toddler temperament, social behavior, and health; birth and adoptive parent personality characteristics, psychopathology, competence, stress, and substance use; adoptive parenting and marital relations; and prenatal exposure to drugs and maternal stress. Preliminary analyses suggest the representativeness of the sample and minimal confounding effects of current trends in adoption practices, including openness and selective placement. Future plans are described.

  20. The Early Growth and Development Study: A Prospective Adoption Design

    PubMed Central

    Leve, Leslie D.; Neiderhiser, Jenae M.; Ge, Xiaojia; Scaramella, Laura V.; Conger, Rand D.; Reid, John B.; Shaw, Daniel S.; Reiss, David

    2014-01-01

    The Early Growth and Development Study is a prospective adoption study of birth parents, adoptive parents, and adopted children (N = 350 triads) that was initiated in 2003. The primary study aims are to examine how family processes mediate or moderate the expression of genetic influences in order to aid in the identification of specific family processes that could serve as malleable targets for intervention. Participants in the study were recruited following the birth of the child through adoption agencies located throughout the United States. Assessments occur at 6-month intervals until child age 3 years. Data collection includes the following primary constructs: infant/toddler temperament, social behavior, and health; birth and adoptive parent personality characteristics, psychopathology, competence, stress, and substance use; adoptive parenting and marital relations; and prenatal exposure to drugs and maternal stress. Preliminary analyses suggest the representativeness of the sample and minimal confounding effects of current trends in adoption practices, including openness and selective placement. Future plans are described. PMID:17539368

  1. Mixture effects of 30 environmental contaminants on incident metabolic syndrome-A prospective study.

    PubMed

    Lind, Lars; Salihovic, Samira; Lampa, Erik; Lind, P Monica

    2017-10-01

    Several cross-sectional studies have linked different environmental contaminants to the metabolic syndrome (MetS). However, mixture effects have not been investigated and no prospective studies exist regarding environmental contaminants and the MetS. To study mixture effects of contaminants on the risk of incident MetS in a prospective fashion. Our sample consisted of 452 subjects from the Prospective Study of the Vasculature in Uppsala Seniors (PIVUS) study (50% women, all aged 70years) free from the MetS at baseline, being followed for 10years. At baseline, 30 different environmental contaminants were measured; 6 polychlorinated biphenyls (PCBs), 3 organochlorine (OC) pesticides, one dioxin, one polybrominated diphenyl ether (all in plasma), 8 perfluoroalkyl substances (in plasma) and 11 metals (in whole blood). The MetS was defined by the ATPIII/NCEP criteria. Gradient boosted Classification and Regression Trees (CARTs) was used to evaluate potential synergistic and additive mixture effects on incident MetS. During 10-year follow-up, 92 incident cases of the MetS occurred. PCB126, PCB170, hexachlorobenzene (HCB) and PCB118 levels were all associated with incident MetS in an additive fashion (OR 1.73 for a change from 10th to 90th percentile (95%CI 1.24-3.04) for PCB126, OR 0.63 (0.42-0.78) for PCB170, OR 1.44 (1.09-2.20) for HCB and OR 1.46 (1.13-2.43) for PCB118). No synergistic effects were found. A mixture of environmental contaminants, with PCB126, PCB170, HCB and PCB118 being the most important, showed associations with future development of the MetS in an additive fashion in this prospective study. Thus, mixture effects of environmental contaminants could contribute to the development of cardio-metabolic derangements. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  2. Hydrogen production by Cyanobacteria.

    PubMed

    Dutta, Debajyoti; De, Debojyoti; Chaudhuri, Surabhi; Bhattacharya, Sanjoy K

    2005-12-21

    The limited fossil fuel prompts the prospecting of various unconventional energy sources to take over the traditional fossil fuel energy source. In this respect the use of hydrogen gas is an attractive alternate source. Attributed by its numerous advantages including those of environmentally clean, efficiency and renew ability, hydrogen gas is considered to be one of the most desired alternate. Cyanobacteria are highly promising microorganism for hydrogen production. In comparison to the traditional ways of hydrogen production (chemical, photoelectrical), Cyanobacterial hydrogen production is commercially viable. This review highlights the basic biology of cynobacterial hydrogen production, strains involved, large-scale hydrogen production and its future prospects. While integrating the existing knowledge and technology, much future improvement and progress is to be done before hydrogen is accepted as a commercial primary energy source.

  3. A global overview of biotech (GM) crops: adoption, impact and future prospects.

    PubMed

    James, Clive

    2010-01-01

    In the early 1990s, some were skeptical that genetically modified (GM) crops, now referred to as biotech crops, could deliver improved products and make an impact at the farm level. There was even more skepticism that developing countries would adopt biotech crops. The adoption of and commercialization of biotech crops in 2008 is reviewed. The impact of biotech crops are summarized including their contribution to: global food, feed and fiber security; a safer environment; a more sustainable agriculture; and the alleviation of poverty, and hunger in the developing countries of the world. Future prospects are discussed. Notably, Egypt planted Bt maize for the first time in 2008 thereby becoming the first country in the Arab world to commercialize biotech crops.

  4. A behavioural and neural evaluation of prospective decision-making under risk

    PubMed Central

    Symmonds, Mkael; Bossaerts, Peter; Dolan, Raymond J.

    2010-01-01

    Making the best choice when faced with a chain of decisions requires a person to judge both anticipated outcomes and future actions. Although economic decision-making models account for both risk and reward in single choice contexts there is a dearth of similar knowledge about sequential choice. Classical utility-based models assume that decision-makers select and follow an optimal pre-determined strategy, irrespective of the particular order in which options are presented. An alternative model involves continuously re-evaluating decision utilities, without prescribing a specific future set of choices. Here, using behavioral and functional magnetic resonance imaging (fMRI) data, we studied human subjects in a sequential choice task and use these data to compare alternative decision models of valuation and strategy selection. We provide evidence that subjects adopt a model of re-evaluating decision utilities, where available strategies are continuously updated and combined in assessing action values. We validate this model by using simultaneously-acquired fMRI data to show that sequential choice evokes a pattern of neural response consistent with a tracking of anticipated distribution of future reward, as expected in such a model. Thus, brain activity evoked at each decision point reflects the expected mean, variance and skewness of possible payoffs, consistent with the idea that sequential choice evokes a prospective evaluation of both available strategies and possible outcomes. PMID:20980595

  5. A behavioral and neural evaluation of prospective decision-making under risk.

    PubMed

    Symmonds, Mkael; Bossaerts, Peter; Dolan, Raymond J

    2010-10-27

    Making the best choice when faced with a chain of decisions requires a person to judge both anticipated outcomes and future actions. Although economic decision-making models account for both risk and reward in single-choice contexts, there is a dearth of similar knowledge about sequential choice. Classical utility-based models assume that decision-makers select and follow an optimal predetermined strategy, regardless of the particular order in which options are presented. An alternative model involves continuously reevaluating decision utilities, without prescribing a specific future set of choices. Here, using behavioral and functional magnetic resonance imaging (fMRI) data, we studied human subjects in a sequential choice task and use these data to compare alternative decision models of valuation and strategy selection. We provide evidence that subjects adopt a model of reevaluating decision utilities, in which available strategies are continuously updated and combined in assessing action values. We validate this model by using simultaneously acquired fMRI data to show that sequential choice evokes a pattern of neural response consistent with a tracking of anticipated distribution of future reward, as expected in such a model. Thus, brain activity evoked at each decision point reflects the expected mean, variance, and skewness of possible payoffs, consistent with the idea that sequential choice evokes a prospective evaluation of both available strategies and possible outcomes.

  6. Model-based choices involve prospective neural activity

    PubMed Central

    Doll, Bradley B.; Duncan, Katherine D.; Simon, Dylan A.; Shohamy, Daphna; Daw, Nathaniel D.

    2015-01-01

    Decisions may arise via “model-free” repetition of previously reinforced actions, or by “model-based” evaluation, which is widely thought to follow from prospective anticipation of action consequences using a learned map or model. While choices and neural correlates of decision variables sometimes reflect knowledge of their consequences, it remains unclear whether this actually arises from prospective evaluation. Using functional MRI and a sequential reward-learning task in which paths contained decodable object categories, we found that humans’ model-based choices were associated with neural signatures of future paths observed at decision time, suggesting a prospective mechanism for choice. Prospection also covaried with the degree of model-based influences on neural correlates of decision variables, and was inversely related to prediction error signals thought to underlie model-free learning. These results dissociate separate mechanisms underlying model-based and model-free evaluation and support the hypothesis that model-based influences on choices and neural decision variables result from prospection. PMID:25799041

  7. Solar paint: From synthesis to printing

    DOE PAGES

    Zhou, Xiaojing; Belcher, Warwick; Dastoor, Paul

    2014-11-13

    Water-based polymer nanoparticle dispersions (solar paint) offer the prospect of addressing two of the main challenges associated with printing large area organic photovoltaic devices; namely, how to control the nanoscale architecture of the active layer and eliminate the need for hazardous organic solvents during device fabrication. We review progress in the field of nanoparticulate organic photovoltaic (NPOPV) devices and future prospects for large-scale manufacturing of solar cells based on this technology.

  8. Solar paint: From synthesis to printing

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhou, Xiaojing; Belcher, Warwick; Dastoor, Paul

    Water-based polymer nanoparticle dispersions (solar paint) offer the prospect of addressing two of the main challenges associated with printing large area organic photovoltaic devices; namely, how to control the nanoscale architecture of the active layer and eliminate the need for hazardous organic solvents during device fabrication. We review progress in the field of nanoparticulate organic photovoltaic (NPOPV) devices and future prospects for large-scale manufacturing of solar cells based on this technology.

  9. Human pursuance of equality hinges on mental processes of projecting oneself into the perspectives of others and into future situations.

    PubMed

    Takesue, Hirofumi; Miyauchi, Carlos Makoto; Sakaiya, Shiro; Fan, Hongwei; Matsuda, Tetsuya; Kato, Junko

    2017-07-19

    In the pursuance of equality, behavioural scientists disagree about distinct motivators, that is, consideration of others and prospective calculation for oneself. However, accumulating data suggest that these motivators may share a common process in the brain whereby perspectives and events that did not arise in the immediate environment are conceived. To examine this, we devised a game imitating a real decision-making situation regarding redistribution among income classes in a welfare state. The neural correlates of redistributive decisions were examined under contrasting conditions, with and without uncertainty, which affects support for equality in society. The dorsal anterior cingulate cortex (dACC) and the caudate nucleus were activated by equality decisions with uncertainty but by selfless decisions without uncertainty. Activation was also correlated with subjective values. Activation in both the dACC and the caudate nucleus was associated with the attitude to prefer accordance with others, whereas activation in the caudate nucleus reflected that the expected reward involved the prospective calculation of relative income. The neural correlates suggest that consideration of others and prospective calculation for oneself may underlie the support for equality. Projecting oneself into the perspective of others and into prospective future situations may underpin the pursuance of equality.

  10. Quality of life and anxiety in women with breast cancer before and after treatment

    PubMed Central

    Villar, Raquel Rey; Fernández, Salvador Pita; Garea, Carmen Cereijo; Pillado, Mª Teresa Seoane; Barreiro, Vanesa Balboa; Martín, Cristina González

    2017-01-01

    ABSTRACT Objectives: to determine the quality of life and anxiety in patients with breast cancer and the changes they experience after treatments. Method: prospective study. Breast cancer statistics (n=339, confidence=95%, accuracy= ± 5.32%). The quality of life questionnaires (QLQ) used were QLQ C-30 and QLQ Br23, and the State-Trait Anxiety Inventory (STAI) was used for anxiety. A multivariate analysis was performed to identify variables associated with baseline quality of life and anxiety as well as pre- and post-treatment differences. Authorization was obtained from the Ethics Committee, and informed consent was provided by all patients. Results: the baseline quality of life dimensions with the lowest score were future prospects (46.0/100) and sexual enjoyment (55.7/100). The dimensions with the highest score were body image (94.2/100) and role (93.3/100). The most disturbing symptoms were insomnia, fatigue and concern about hair loss. After treatment, the dimensions of physical function, role, body image, financial concerns and symptomatology worsened, whereas emotional function and future prospects improved. Severe anxiety presented as a state (48.6%) and as a trait (18.2%). The highest baseline state anxiety was associated with married-widowed status and anxiolytic medication. The greatest trait anxiety was associated with an inactive work situation, anxiolytic medication, breast swelling and advanced stage at diagnosis. After treatment, anxiety significantly decreased. Conclusions: After treatment, the quality of life score was positively modified, while state and trait anxiety decreased. PMID:29267541

  11. Quality of life and anxiety in women with breast cancer before and after treatment.

    PubMed

    Villar, Raquel Rey; Fernández, Salvador Pita; Garea, Carmen Cereijo; Pillado, Mª Teresa Seoane; Barreiro, Vanesa Balboa; Martín, Cristina González

    2017-12-21

    to determine the quality of life and anxiety in patients with breast cancer and the changes they experience after treatments. prospective study. Breast cancer statistics (n=339, confidence=95%, accuracy= ± 5.32%). The quality of life questionnaires (QLQ) used were QLQ C-30 and QLQ Br23, and the State-Trait Anxiety Inventory (STAI) was used for anxiety. A multivariate analysis was performed to identify variables associated with baseline quality of life and anxiety as well as pre- and post-treatment differences. Authorization was obtained from the Ethics Committee, and informed consent was provided by all patients. the baseline quality of life dimensions with the lowest score were future prospects (46.0/100) and sexual enjoyment (55.7/100). The dimensions with the highest score were body image (94.2/100) and role (93.3/100). The most disturbing symptoms were insomnia, fatigue and concern about hair loss. After treatment, the dimensions of physical function, role, body image, financial concerns and symptomatology worsened, whereas emotional function and future prospects improved. Severe anxiety presented as a state (48.6%) and as a trait (18.2%). The highest baseline state anxiety was associated with married-widowed status and anxiolytic medication. The greatest trait anxiety was associated with an inactive work situation, anxiolytic medication, breast swelling and advanced stage at diagnosis. After treatment, anxiety significantly decreased. After treatment, the quality of life score was positively modified, while state and trait anxiety decreased.

  12. Forward-Thinking Teens: The Effects of College Costs on Adolescent Risky Behavior

    PubMed Central

    Cowan, Benjamin W.

    2011-01-01

    This paper analyzes the effect of college costs on teenagers’ engagement in risky behaviors before they are old enough to attend college. Individuals with brighter prospects for future schooling attainment may engage in less drug and alcohol use and risky sexual activity because they have more to lose if such behaviors have harmful effects in their lives. If teens correctly predict that higher college costs make future college enrollment less likely, then adolescents facing different expected costs may choose different levels of risky behavior. I find that lower college costs in teenagers’ states of residence raise their subjective expectations regarding college attendance and deter teenage substance use and sexual partnership. Specifically, a $1,000 reduction in tuition and fees at two-year colleges in a youth’s state of residence (roughly a 50% difference at the mean) is associated with a decline in the number of sexual partners the youth had in the past year (by 26%), the number of days in the past month the youth smoked (by 14%), and the number of days in the past month the youth used marijuana (by 23%). These findings suggest that the often-studied correlation between schooling and health habits emerges in adolescence because teenagers with brighter college prospects curb their risky behavior in accordance with their expectations. The results also imply that policies that improve teenagers’ educational prospects may be effective tools for reducing youthful involvement in such behaviors. PMID:21886942

  13. Galaxies in the X-Ray Band

    NASA Technical Reports Server (NTRS)

    Hornschemeier, Ann

    2008-01-01

    This talk will provide a brief review of progress an X-ray emission from normal (non-AGN) galaxy populations, including important constraints on the evolution of accreting binary populations over important cosmological timescales. We will also look to the future, anticipating constraints from near-term imaging hard X-ray missions such as NuSTAR, Simbol-X and NeXT and then the longer-term prospects for studying galaxies with the Generation-X mission,

  14. Galaxies in the X-ray Band

    NASA Technical Reports Server (NTRS)

    Hornschemeier, Ann

    2008-01-01

    This talk will provide a brief review of progress on X-ray emission from normal (non-AGN) galaxy populations, including important constraints on the evolution of accreting binary populations over important cosmological timescales. We will also look to the future, anticipating constraints from near-term imaging hard X-ray missions such as NuSTAR, Simbol-X and NeXT and then the longer-term prospects for studying galaxies with the Generation-X mission.

  15. Penetrating missile injuries during asymmetric warfare in the 2003 Gulf conflict.

    PubMed

    Hinsley, D E; Rosell, P A E; Rowlands, T K; Clasper, J C

    2005-05-01

    War wounds produce a significant burden on medical facilities in wartime. Workload from the recent conflict was documented in order to guide future medical needs. All data on war injuries were collected prospectively. This information was supplemented with a review of all patients admitted during the study period. During the first 2 weeks of the conflict, the sole British field hospital in the region received 482 casualties. One hundred and four were battle injuries of which nine were burns. Seventy-nine casualties had their initial surgery performed by British military surgeons and form the study group. Twenty-nine casualties (37 per cent) sustained gunshot wounds, 49 (62 per cent) suffered wounds from fragmentation weapons and one casualty detonated an antipersonnel mine. These 79 patients had a total of 123 wounds that were scored prospectively using the Red Cross Wound Classification. Twenty-seven (34 per cent) of the wounded were non-combatants; eight of these were children. Four patients (5 per cent) died. War is changing; modern conflicts appear likely to be fought in urban or remote environments, producing different wounding patterns and placing non-combatants in the line of fire. Military medical skills training and available resources must reflect these fundamental changes in preparation for future conflicts.

  16. Rope Hadronization and Strange Particle Production

    NASA Astrophysics Data System (ADS)

    Bierlich, Christian

    2018-02-01

    Rope Hadronization is a model extending the Lund string hadronization model to describe environments with many overlapping strings, such as high multiplicity pp collisions or AA collisions. Including effects of Rope Hadronization drastically improves description of strange/non-strange hadron ratios as function of event multiplicity in all systems from e+e- to AA. Implementation of Rope Hadronization in the MC event generators Dipsy and PYTHIA8 is discussed, as well as future prospects for jet studies and studies of small systems.

  17. Prospective Safety Analysis and the Complex Aviation System

    NASA Technical Reports Server (NTRS)

    Smith, Brian E.

    2013-01-01

    Fatal accident rates in commercial passenger aviation are at historic lows yet have plateaued and are not showing evidence of further safety advances. Modern aircraft accidents reflect both historic causal factors and new unexpected "Black Swan" events. The ever-increasing complexity of the aviation system, along with its associated technology and organizational relationships, provides fertile ground for fresh problems. It is important to take a proactive approach to aviation safety by working to identify novel causation mechanisms for future aviation accidents before they happen. Progress has been made in using of historic data to identify the telltale signals preceding aviation accidents and incidents, using the large repositories of discrete and continuous data on aircraft and air traffic control performance and information reported by front-line personnel. Nevertheless, the aviation community is increasingly embracing predictive approaches to aviation safety. The "prospective workshop" early assessment tool described in this paper represents an approach toward this prospective mindset-one that attempts to identify the future vectors of aviation and asks the question: "What haven't we considered in our current safety assessments?" New causation mechanisms threatening aviation safety will arise in the future because new (or revised) systems and procedures will have to be used under future contextual conditions that have not been properly anticipated. Many simulation models exist for demonstrating the safety cases of new operational concepts and technologies. However the results from such models can only be as valid as the accuracy and completeness of assumptions made about the future context in which the new operational concepts and/or technologies will be immersed. Of course that future has not happened yet. What is needed is a reasonably high-confidence description of the future operational context, capturing critical contextual characteristics that modulate both the likelihood of occurrence of hazards, and the likelihood that those hazards will lead to negative safety events. Heuristics extracted from scenarios, questionnaires, and observed trends from scanning the aviation horizon may be helpful in capturing those future changes in a way conducive to safety assessment. What is also needed is a checklist of potential sources of emerging risk that arise from organizational features that are frequently overlooked. The ultimate goal is to develop a pragmatic, workable method for using descriptions of the future aviation context, to generate valid predictions of safety risks.

  18. Two Energy Futures: A National Choice for the 80s.

    ERIC Educational Resources Information Center

    American Petroleum Inst., Washington, DC.

    In 1980, the American Petroleum Institute published the first edition of "Two Energy Futures." It described the U.S. energy experience of the 1970s and prospects for the 1980s, concluding that the nation could drastically reduce its dependence on uncertain sources of imported oil if the right choices were made by individuals and the…

  19. Lifelong Learning through the SkillsFuture Movement in Singapore: Challenges and Prospects

    ERIC Educational Resources Information Center

    Tan, Charlene

    2017-01-01

    This article examines the promotion of lifelong learning (LLL) in Singapore through a new national initiative known as the SkillsFuture movement. It is argued that the attainment of LLL is confronted with three key challenges, the first being the sociocultural preference for academic rather than vocational education in Singapore. Secondly, there…

  20. Overview of radar intra-pulse modulation recognition

    NASA Astrophysics Data System (ADS)

    Zang, Hanlin; Li, Yanling

    2018-05-01

    This paper introduces the current radar intra-pulse modulation method, describes the status quo and development direction of the intentional modulation and unintentional modulation in the pulse, and summarizes the existing problems and prospects for the future. Looking forward to the future, and providing a reference direction for the research on radar signal recognition in the next step.

  1. Penny Wise, Pound Foolish?: Don't Sacrifice Our Nation's Future

    ERIC Educational Resources Information Center

    Murguia, Janet; Arroyo, Liany Elba, Ed.; Miranda, Leticia, Ed.

    2011-01-01

    The United States has provided generations of its residents with the prospect of advancing themselves through education and hard work, and U.S. leaders have the opportunity to make sure this continues for generations to come. To do so, they must handle the national deficit in a decisive, thoughtful manner, ensuring a prosperous future for the…

  2. Organizational Learning and the Learning Organization: Reviewing Evolution for Prospecting the Future

    ERIC Educational Resources Information Center

    Rebelo, Teresa Manuela; Gomes, Adelino Duarte

    2008-01-01

    Purpose: The purpose of this article is to analyse the evolution of the concepts of organizational learning and the learning organization and propose guidelines for the future. Design/methodology/approach: The evolution of organizational learning and the learning organization is analysed in the light of the three-stage model of the evolution of…

  3. The Roles of Artificial Intelligence in Education: Current Progress and Future Prospects

    ERIC Educational Resources Information Center

    McArthur, David; Lewis, Matthew; Bishary, Miriam

    2005-01-01

    This report begins by summarizing current applications of ideas from artificial intelligence (Al) to education. It then uses that summary to project various future applications of Al--and advanced technology in general--to education, as well as highlighting problems that will confront the wide­ scale implementation of these technologies in the…

  4. Impaired cue identification and intention retrieval underlie prospective memory deficits in patients with first-episode schizophrenia.

    PubMed

    Liu, Dengtang; Ji, Chengfeng; Zhuo, Kaiming; Song, Zhenhua; Wang, Yingchan; Mei, Li; Zhu, Dianming; Xiang, Qiong; Chen, Tianyi; Yang, Zhilei; Zhu, Guang; Wang, Ya; Cheung, Eric Fc; Xiang, Yu-Tao; Fan, Xiaoduo; Chan, Raymond Ck; Xu, Yifeng; Jiang, Kaida

    2017-03-01

    Schizophrenia is associated with impairment in prospective memory, the ability to remember to carry out an intended action in the future. It has been established that cue identification (detection of the cue event signaling that an intended action should be performed) and intention retrieval (retrieval of an intention from long-term memory following the recognition of a prospective cue) are two important processes underlying prospective memory. The purpose of this study was to examine prospective memory deficit and underlying cognitive processes in patients with first-episode schizophrenia. This study examined cue identification and intention retrieval components of event-based prospective memory using a dual-task paradigm in 30 patients with first-episode schizophrenia and 30 healthy controls. All participants were also administered a set of tests assessing working memory and retrospective memory. Both cue identification and intention retrieval were impaired in patients with first-episode schizophrenia compared with healthy controls ( ps < 0.05), with a large effect size for cue identification (Cohen's d = 0.98) and a medium effect size for intention retrieval (Cohen's d = 0.62). After controlling for working memory and retrospective memory, the difference in cue identification between patients and healthy controls remained significant. However, the difference in intention retrieval between the two groups was no longer significant. In addition, there was a significant inverse relationship between cue identification and negative symptoms ( r = -0.446, p = 0.013) in the patient group. These findings suggest that both cue identification and intention retrieval in event-based prospective memory are impaired in patients with first-episode schizophrenia. Cue identification and intention retrieval could be potentially used as biomarkers for early detection and treatment prognosis of schizophrenia. In addition, addressing cue identification deficit through cognitive enhancement training may potentially improve negative symptoms as well.

  5. Effects of work ability and health promoting interventions for women with musculoskeletal symptoms: A 9-month prospective study

    PubMed Central

    Larsson, Agneta; Karlqvist, Lena; Gard, Gunvor

    2008-01-01

    Background Women working in the public human service sector in 'overstrained' situations run the risk of musculoskeletal symptoms and long-term sick leave. In order to maintain the level of health and work ability and strengthen the potential resources for health, it is important that employees gain greater control over decisions and actions affecting their health – a process associated with the concept of self-efficacy. The aim of this study was to describe the effects of a self-efficacy intervention and an ergonomic education intervention for women with musculoskeletal symptoms, employed in the public sector. Methods The design of the study was a 9-month prospective study describing the effects of two interventions, a comprehensive self-efficacy intervention (n = 21) and an ergonomic education intervention (n = 21). Data were obtained by a self-report questionnaire on health- and work ability-related factors at baseline, and at ten weeks and nine months follow-up. Within-group differences over time were analysed. Results Over the time period studied there were small magnitudes of improvements within each group. Within the self-efficacy intervention group positive effects in perceived work ability were shown. The ergonomic education group showed increased positive beliefs about future work ability and a more frequent use of pain coping strategies. Conclusion Both interventions showed positive effects on women with musculoskeletal symptoms, but in different ways. Future research in this area should tailor interventions to participants' motivation and readiness to change. PMID:18644154

  6. Ion cyclotron emission studies: Retrospects and prospects

    DOE PAGES

    Gorelenkov, N. N.

    2016-06-05

    Ion cyclotron emission (ICE) studies emerged in part from the papers by A.B. Mikhailovskii published in the 1970s. Among the discussed subjects were electromagnetic compressional Alfv,nic cyclotron instabilities with the linear growth rate similar ~ √(n α/n e) driven by fusion products, -particles which draw a lot of attention to energetic particle physics. The theory of ICE excited by energetic particles was significantly advanced at the end of the 20th century motivated by first DT experiments on TFTR and subsequent JET experimental studies which we highlight. Recently ICE theory was advanced by detailed theoretical and experimental studies on spherical torusmore » (ST) fusion devices where the instability signals previously indistinguishable in high aspect ratio tokamaks due to high toroidal magnetic field became the subjects of experiments. Finally, we discuss prospects of ICE theory applications for future burning plasma (BP) experiments such as those to be conducted in ITER device in France, where neutron and gamma rays escaping the plasma create extremely challenging conditions fusion alpha particle diagnostics.« less

  7. Ion cyclotron emission studies: Retrospects and prospects

    NASA Astrophysics Data System (ADS)

    Gorelenkov, N. N.

    2016-05-01

    Ion cyclotron emission (ICE) studies emerged in part from the papers by A.B. Mikhailovskii published in the 1970s. Among the discussed subjects were electromagnetic compressional Alfvénic cyclotron instabilities with the linear growth rate √ {n_α /n_e } driven by fusion products, -particles which draw a lot of attention to energetic particle physics. The theory of ICE excited by energetic particles was significantly advanced at the end of the 20th century motivated by first DT experiments on TFTR and subsequent JET experimental studies which we highlight. More recently ICE theory was advanced by detailed theoretical and experimental studies on spherical torus (ST) fusion devices where the instability signals previously indistinguishable in high aspect ratio tokamaks due to high toroidal magnetic field became the subjects of experiments. We discuss further prospects of ICE theory applications for future burning plasma (BP) experiments such as those to be conducted in ITER device in France, where neutron and gamma rays escaping the plasma create extremely challenging conditions fusion alpha particle diagnostics.

  8. Evaluating the Predictive Impact of an Emergent Literacy Model on Dyslexia in Italian Children: A Four-Year Prospective Cohort Study.

    PubMed

    Bigozzi, Lucia; Tarchi, Christian; Pezzica, Sara; Pinto, Giuliana

    2016-01-01

    The strong differences in manifestation, prevalence, and incidence in dyslexia across languages invite studies in specific writing systems. In particular, the question of the role played by emergent literacy in opaque and transparent writing systems remains a fraught one. This research project tested, through a 4-year prospective cohort study, an emergent literacy model for the analysis of the characteristics of future dyslexic children and normally reading peers in Italian, a transparent writing system. A cohort of 450 children was followed from the last year of kindergarten to the third grade in their reading acquisition process. Dyslexic children were individuated (Grade 3), and their performances in kindergarten in textual competence, phonological awareness, and conceptual knowledge of the writing system were compared with a matched group of normally reading peers. Results showed the predictive relevance of the conceptual knowledge of the writing system. The study's implications are discussed. © Hammill Institute on Disabilities 2014.

  9. Earth Rotation Dynamics: Review and Prospects

    NASA Technical Reports Server (NTRS)

    Chao, Benjamin F.

    2004-01-01

    Modem space geodetic measurement of Earth rotation variations, particularly by means of the VLBI technique, has over the years allowed studies of Earth rotation dynamics to advance in ever-increasing precision, accuracy, and temporal resolution. A review will be presented on our understanding of the geophysical and climatic causes, or "excitations", for length-of-day change, polar motion, and nutations. These excitations sources come from mass transports that constantly take place in the Earth system comprised of the atmosphere, hydrosphere, cryosphere, lithosphere, mantle, and the cores. In this sense, together with other space geodetic measurements of time-variable gravity and geocenter motion, Earth rotation variations become a remote-sensing tool for the integral of all mass transports, providing valuable information about the latter on a wide range of spatial and temporal scales. Future prospects with respect to geophysical studies with even higher accuracy and resolution will be discussed.

  10. The Potential and Limitations of Cross-Context Comparative Research on Migration

    PubMed Central

    Riosmena, Fernando

    2017-01-01

    This article is an overview of household survey approaches for the comparative study of international migration dynamics. Focusing on differences in the drivers of international mobility at different times and places, I highlight the problems of obtaining data with adequate representation across time periods and geographies, and discuss a broad constellation of prospective and retrospective approaches, paying particular attention to the migration ethnosurvey. I place this methodology within a broader constellation of prospective and retrospective data collection techniques, briefly describing the advantages and disadvantages of each and summarizing the commonalities and differences of ethnosurvey approaches adopted around the world. In particular, I discuss the potential and limitations of cross-context research and suggest post hoc case selection and other adjustments to ameliorate problems. I conclude with ideas about how case and sample selection can help to bolster migration studies in the future. PMID:29093598

  11. A Prospective Programmatic Cost Analysis of Fuel Your Life: A Worksite Translation of DPP.

    PubMed

    Ingels, Justin B; Walcott, Rebecca L; Wilson, Mark G; Corso, Phaedra S; Padilla, Heather M; Zuercher, Heather; DeJoy, David M; Vandenberg, Robert J

    2016-11-01

    An accounting of the resources necessary for implementation of efficacious programs is important for economic evaluations and dissemination. A programmatic costs analysis was conducted prospectively in conjunction with an efficacy trial of Fuel Your Life (FYL), a worksite translation of the Diabetes Prevention Program. FYL was implemented through three different modalities, Group, Phone, and Self-study, using a micro-costing approach from both the employer and societal perspectives. The Phone modality was the most costly at $354.6 per participant, compared with $154.6 and $75.5 for the Group and Self-study modalities, respectively. With the inclusion of participant-related costs, the Phone modality was still more expensive than the Group modality but with a smaller incremental difference ($461.4 vs $368.1). This level of cost-related detail for a preventive intervention is rare, and our analysis can aid in the transparency of future economic evaluations.

  12. Is the Use of Protective Behavioral Strategies Associated With College Sexual Assault Victimization? A Prospective Examination

    PubMed Central

    Gilmore, Amanda K.; Maples-Keller, Jessica L.; Pinsky, Hanna T.; Shepard, Molly E.; Lewis, Melissa A.; George, William H.

    2016-01-01

    Sexual assault protective behavioral strategies (PBS) may be negatively associated with sexual assault victimization. However, no studies to date have prospectively examined whether the use of sexual assault PBS is negatively associated with subsequent sexual assault experiences. The current study examined the association between the use of sexual assault PBS and subsequent sexual assault victimization severity. College women who reported engaging in heavy episodic drinking (n = 77) were assessed online for their use of sexual assault PBS and history of sexual assault victimization. In addition, a 3-month follow-up survey was given assessing sexual assault victimization severity in the past 3 months. The use of sexual assault PBS was negatively associated with sexual assault severity in the 3-month follow-up period. Future research should further examine these PBS to create more college-specific PBS and to determine whether they are useful as risk-reduction strategies. PMID:26856359

  13. Future and outlook: Where are we, and where will the spatial information management in wildlife ecology be in 50 years from now? [Chapter 24

    Treesearch

    Samuel A. Cushman; Falk Huettmann

    2010-01-01

    In this final chapter we briefly look back over what we have attempted in this book, and then look toward the future to discuss the outlook for overcoming the challenges we face within our fields of ecological science and in the greater application of this knowledge to enhance the prospect for a sustainable future for the biosphere. Looking back, we have tried...

  14. Successful Fiber Sensing Technologies and Hot Topics for the Near Future

    NASA Astrophysics Data System (ADS)

    López-Higuera, J. M.; Cobo, A.; Conde, Olga; Lomer, M.; Madruga, F.; Quintela, M. A.; Quintela, A.; Mirapeix, J.

    2008-10-01

    Inside the Photonics field Optical Fiber Sensors (OFS) are currently being used and will still be used in the future in a wide number of applications because its properties present technical advantages over traditional techniques or, sometimes, is practically the only feasible solution. In this paper, the more successful techniques will be reviewed. Then a prospective for the near future of the market and hot topics in which invest research resources will be suggested.

  15. Rib fractures predict incident limb fractures: results from the European prospective osteoporosis study.

    PubMed

    Ismail, A A; Silman, A J; Reeve, J; Kaptoge, S; O'Neill, T W

    2006-01-01

    Population studies suggest that rib fractures are associated with a reduction in bone mass. While much is known about the predictive risk of hip, spine and distal forearm fracture on the risk of future fracture, little is known about the impact of rib fracture. The aim of this study was to determine whether a recalled history of rib fracture was associated with an increased risk of future limb fracture. Men and women aged 50 years and over were recruited from population registers in 31 European centres for participation in a screening survey of osteoporosis (European Prospective Osteoporosis Study). Subjects were invited to complete an interviewer-administered questionnaire that included questions about previous fractures including rib fracture, the age of their first fracture and also the level of trauma. Lateral spine radiographs were performed and the presence of vertebral deformity was determined morphometrically. Following the baseline survey, subjects were followed prospectively by annual postal questionnaire to determine the occurrence of clinical fractures. The subjects included 6,344 men, with a mean age of 64.2 years, and 6,788 women, with a mean age of 63.6 years, who were followed for a median of 3 years (range 0.4-5.9 years), of whom 135 men (2.3%) and 101 women (1.6%) reported a previous low trauma rib fracture. In total, 138 men and 391 women sustained a limb fracture during follow-up. In women, after age adjustment, those with a recalled history of low trauma rib fracture had an increased risk of sustaining 'any' limb fracture [relative hazard (RH)=2.3; 95% CI 1.3, 4.0]. When stratified by fracture type the predictive risk was more marked for hip (RH=7.7; 95% CI 2.3, 25.9) and humerus fracture (RH=4.5; 95% CI 1.4, 14.6) than other sites (RH=1.6; 95% CI 0.6, 4.3). Additional adjustment for prevalent vertebral deformity and previous (non-rib) low trauma fractures at other sites slightly reduced the strength of the association between rib fracture and subsequent limb fracture. In men, after age adjustment, there was a small though non-significant association between recalled history of rib fracture and future limb fracture. Our data highlight the importance of rib fracture as a marker of bone fragility in women.

  16. Psychosis prediction and clinical utility in familial high-risk studies: Selective review, synthesis, and implications for early detection and intervention

    PubMed Central

    Shah, Jai L.; Tandon, Neeraj; Keshavan, Matcheri S.

    2016-01-01

    Aim Accurate prediction of which individuals will go on to develop psychosis would assist early intervention and prevention paradigms. We sought to review investigations of prospective psychosis prediction based on markers and variables examined in longitudinal familial high-risk (FHR) studies. Methods We performed literature searches in MedLine, PubMed and PsycINFO for articles assessing performance characteristics of predictive clinical tests in FHR studies of psychosis. Studies were included if they reported one or more predictive variables in subjects at FHR for psychosis. We complemented this search strategy with references drawn from articles, reviews, book chapters and monographs. Results Across generations of familial high-risk projects, predictive studies have investigated behavioral, cognitive, psychometric, clinical, neuroimaging, and other markers. Recent analyses have incorporated multivariate and multi-domain approaches to risk ascertainment, although with still generally modest results. Conclusions While a broad range of risk factors has been identified, no individual marker or combination of markers can at this time enable accurate prospective prediction of emerging psychosis for individuals at FHR. We outline the complex and multi-level nature of psychotic illness, the myriad of factors influencing its development, and methodological hurdles to accurate and reliable prediction. Prospects and challenges for future generations of FHR studies are discussed in the context of early detection and intervention strategies. PMID:23693118

  17. Analysis of Science and Technology Trend Based on Word Usage in Digitized Books

    NASA Astrophysics Data System (ADS)

    Yun, Jinhyuk; Kim, Pan-Jun; Jeong, Hawoong

    2013-03-01

    Throughout mankind's history, forecasting and predicting future has been a long-lasting interest to our society. Many fortune-tellers have tried to forecast the future by ``divine'' items. Sci-fi writers have also imagined what the future would look like. However most of them have been illogical and unscientific. Meanwhile, scientists have also attempted to discover future trend of science. Many researchers have used quantitative models to study how new ideas are used and spread. Besides the modeling works, in the early 21st century, the rise of data science has provided another prospect of forecasting future. However many studies have focused on very limited set of period or age, due to the limitations of dataset. Hence, many questions still remained unanswered. Fortunately, Google released a new dataset named ``Google N-Gram Dataset.'' This dataset provides us with 5 million words worth of literature dating from 1520 to 2008, and this is nearly 4% of publications ever printed. With this new time-varying dataset, we studied the spread and development of technologies by searching ``Science and Technology'' related words from 1800 to 2000. By statistical analysis, some general scaling laws were discovered. And finally, we determined factors that strongly affect the lifecycle of a word.

  18. Prediagnostic serum levels of inflammatory biomarkers are correlated with future development of lung and esophageal cancer

    PubMed Central

    Keeley, Brieze R; Islami, Farhad; Pourshams, Akram; Poustchi, Hossein; Pak, Jamie S; Brennan, Paul; Khademi, Hooman; Genden, Eric M; Abnet, Christian C; Dawsey, Sanford M; Boffetta, Paolo; Malekzadeh, Reza; Sikora, Andrew G

    2014-01-01

    This study tests the hypothesis that prediagnostic serum levels of 20 cancer-associated inflammatory biomarkers correlate directly with future development of head and neck, esophageal, and lung cancers in a high-risk prospective cohort. This is a nested case–control pilot study of subjects enrolled in the Golestan Cohort Study, an ongoing epidemiologic project assessing cancer trends in Golestan, Iran. We measured a panel of 20 21cytokines, chemokines, and inflammatory molecules using Luminex technology in serum samples collected 2 or more years before cancer diagnosis in 78 aerodigestive cancer cases and 81 controls. Data was analyzed using Wilcoxon rank sum test, odds ratios, receiver operating characteristic areas of discrimination, and multivariate analysis. Biomarkers were profoundly and globally elevated in future esophageal and lung cancer patients compared to controls. Odds ratios were significant for association between several biomarkers and future development of esophageal cancer, including interleukin-1Rα (IL-1Ra; 35.9), interferon α2 (IFN-a2; 34.0), fibroblast growth factor-2 (FGF-2; 17.4), and granulocyte/macrophage colony-stimulating factor (GM-CSF; 17.4). The same pattern was observed among future lung cancer cases for G-CSF (27.7), GM-CSF (13.3), and tumor necrosis factor-α (TNF-a; 8.6). By contrast, the majority of biomarkers studied showed no significant correlation with future head and neck cancer development. This study provides the first direct evidence that multiple inflammatory biomarkers are coordinately elevated in future lung and esophageal cancer patients 2 or more years before cancer diagnosis. PMID:25040886

  19. Consolidation of Prospective Memory: Effects of Sleep on Completed and Reinstated Intentions

    PubMed Central

    Barner, Christine; Seibold, Mitja; Born, Jan; Diekelmann, Susanne

    2017-01-01

    Sleep has been shown to facilitate the consolidation of prospective memory, which is the ability to execute intended actions at the appropriate time in the future. In a previous study, the sleep benefit for prospective memory was mainly expressed as a preservation of prospective memory performance under divided attention as compared to full attention. Based on evidence that intentions are only remembered as long as they have not been executed yet (cf. ‘Zeigarnik effect’), here we asked whether the enhancement of prospective memory by sleep vanishes if the intention is completed before sleep and whether completed intentions can be reinstated to benefit from sleep again. In Experiment 1, subjects learned cue-associate word pairs in the evening and were prospectively instructed to detect the cue words and to type in the associates in a lexical decision task (serving as ongoing task) 2 h later before a night of sleep or wakefulness. At a second surprise test 2 days later, sleep and wake subjects did not differ in prospective memory performance. Specifically, both sleep and wake groups detected fewer cue words under divided compared to full attention, indicating that sleep does not facilitate the consolidation of completed intentions. Unexpectedly, in Experiment 2, reinstating the intention, by instructing subjects about the second test after completion of the first test, was not sufficient to restore the sleep benefit. However, in Experiment 3, where subjects were instructed about both test sessions immediately after learning, sleep facilitated prospective memory performance at the second test after 2 days, evidenced by comparable cue word detection under divided attention and full attention in sleep participants, whereas wake participants detected fewer cue words under divided relative to full attention. Together, these findings show that for prospective memory to benefit from sleep, (i) the intention has to be active across the sleep period, and (ii) the intention should be induced in temporal proximity to the initial learning session. PMID:28111558

  20. PREFACE: Prospects in Neutrino Physics 2013 - NuPhys2013

    NASA Astrophysics Data System (ADS)

    2015-04-01

    The first "Prospects in Neutrino Physics 2013 - NuPhys2013" conference was held at the Institute of Physics, IoP, London, 19-20 December 2013 and was attended by about 130 delegates from institutions worldwide. Lunch and coffee breaks allowed discussions among delegates and speakers to take place in an informal setting. This conference is unique in discussing the worldwide strategy to address unresolved issues in neutrino physics, and shape the future directions of particle physics. We discussed the current status and focussed especially on the prospects of future experiments, their performance and physics reach. It is particularly timely due to the recent measurements in neutrino physics and planned worldwide experiments. The following topics were addressed: • Theory and Phenomenology Perspectives • Future Long and Short Baseline Neutrino Oscillation Experiments • Reactor neutrino and flux • Neutrinoless double beta decays • Solar, atmospheric, supernova neutrinos • Neutrino cosmology in which both the phenomenological and experimental aspects were equally addressed. World-leading experts in the different neutrino areas were invited to give review talks. To encourage and facilitate the participation of early-career researchers and PhD students, a poster session formed a key aspect of this meeting. The conference was organized by Francesca Di Lodovico and Silvia Pascoli. It was sponsored by the IoP through their Topic Research Meeting Grant, and also supported by Durham IPPP, ERC-207282, FP7 invisibles project, Queen Mary University of London.

  1. Mineral resource potential map of the Bighorn Mountains Wilderness Study Area (CDCA-217), San Bernardino County, California

    USGS Publications Warehouse

    Matti, Jonathan C.; Cox, Brett F.; Rodriguez, Eduardo A.; Obi, Curtis M.; Powell, Robert E.; Hinkle, Margaret E.; Griscom, Andrew; Sabine, Charles; Cwick, Gary J.

    1982-01-01

    Geological, geochemical, and geophysical evidence, together with a review of historical mining and prospecting activities, suggests that most of the Bighorn Mountains Wilderness Study Area has low potential for the discovery of all types of mineral and energy resources-including precious and base metals, building stone and aggregate, fossil fuels, radioactive-mineral resources, and geothermal resources. Low-grade mineralization has been documented in one small area near Rattlesnake Canyon, and this area has low to moderate potential for future small-scale exploration and development of precious and base metals. Thorium and uranium enrichment have been documented in two small areas in the eastern part of the wilderness study area; these two areas have low to moderate potential for future small-scale exploration and development of radioactive-mineral resources.

  2. Measuring hot flash phenomenonology using ambulatory prospective digital diaries.

    PubMed

    Fisher, William I; Thurston, Rebecca C

    2016-11-01

    This study provides the description, protocol, and results from a novel prospective ambulatory digital hot flash phenomenon diary. This study included 152 midlife women with daily hot flashes who completed an ambulatory electronic hot flash diary continuously for the waking hours of three consecutive days. In this diary, women recorded their hot flashes and accompanying characteristics and associations as the hot flashes occurred. Self-reported hot flash severity on the digital diaries indicated that the majority of hot flashes were rated as mild (41.3%) or moderate (43.7%). Severe (13.1%) and very severe (1.8%) hot flashes were less common. Hot flash bother ratings were rated as mild (43%), or moderate (33.5%), with fewer hot flashes reported bothersome (17.5%) or very bothersome (6%). The majority of hot flashes were reported as occurring on the face (78.9%), neck (74.7%), and chest (61.3%). Of all reported hot flashes, 32% occurred concurrently with prickly skin, 7% with anxiety, and 5% with nausea. A novel finding from the study was that 38% of hot flashes were accompanied by a premonitory aura. A prospective electronic digital hot flash diary allows for a more precise quantitation of hot flashes while overcoming many of the limitations of commonly used retrospective questionnaires and paper diaries. Unique insights into the phenomenology, loci, and associated characteristics of hot flashes were obtained using this device. The digital hot flash phenomenology diary is recommended for future ambulatory studies of hot flashes as a prospective measure of the hot flash experience.

  3. Reply to Comments.

    PubMed

    Sripada, Chandra; Railton, Peter; Baumeister, Roy F; Seligman, Martin E P

    2013-03-01

    Evidence of prospective processes is increasingly common in psychological research, which suggests the fruitfulness of a theoretical framework for mind and brain built around future orientation. No metaphysics of determinism or indeterminism is presupposed by this framework, nor do considerations of scientific method require determinism-successful scientific theories in the natural sciences all involve probabilistic elements. We speculate that expressive behavior and moral decision making use prospective processes parallel to those used in nonmoral decisions. © The Author(s) 2013.

  4. Superconducting RF, the History, Challenges and Promise

    ScienceCinema

    Padamsee, Hasan

    2018-01-01

    After a short survey of on-going accelerator applications, I will discuss future applications prospects for this enabling technology, both near term and long term. A selection of technology highlights will serve as an introduction to outstanding issues for all types of applications, from pulsed high gradient to CW medium gradient. Finally I will touch upon the limits of niobium and the prospects of new materials. The talk will be targeted at a general audience.

  5. Present state of HDTV coding in Japan and future prospect

    NASA Astrophysics Data System (ADS)

    Murakami, Hitomi

    The development status of HDTV digital codecs in Japan is evaluated; several bit rate-reduction codecs have been developed for 1125 lines/60-field HDTV, and performance trials have been conducted through satellite and optical fiber links. Prospective development efforts will attempt to achieve more efficient coding schemes able to reduce the bit rate to as little as 45 Mbps, as well as to apply coding schemes to automated teller machine networks.

  6. White-tailed deer in the Midwest.

    Treesearch

    USDA FS

    1970-01-01

    Discusses the present status and future prospects of the nonyarding white-tailed deer population in the Midwestern United States. Range appraisal, habitat, harvest regulation, and population control are included.

  7. Laser-Driven Fusion.

    ERIC Educational Resources Information Center

    Gibson, A. F.

    1980-01-01

    Discusses the present status and future prospects of laser-driven fusion. Current research (which is classified under three main headings: laser-matter interaction processes, compression, and laser development) is also presented. (HM)

  8. Effects of child interview tactics on prospective jurors' decisions.

    PubMed

    Johnson, Jonni L; Shelley, Alexandra E

    2014-01-01

    Although decisions in child sexual abuse (CSA) cases are influenced by many factors (e.g., child age, juror gender), case and trial characteristics (e.g., interview quality) can strongly influence legal outcomes. In the present study, 319 prospective jurors read about a CSA investigation in which the alleged victim was interviewed at a child advocacy center (CAC) or traditional police setting. The prospective jurors then provided legally relevant ratings (e.g., child credibility, interview quality, defendant guilt). Structural equation modeling techniques revealed that child credibility predicted greater confidence in guilt decisions and also mediated all associations with such decisions. Having fewer negative prior opinions and rating the interview as of better quality were associated with higher child credibility ratings. Mitigating factors (e.g., interview quality), as opposed to proxy indicators (e.g., participant gender), better predicted CSA case outcomes. Similar associations across groups (e.g., CAC interviews did not make child victims more or less credible) permit a tentative conclusion that CACs do not positively or negatively affect decisions made in hypothetical CSA cases. Ideas for future studies examining factors influencing decisions in CSA cases are discussed. Copyright © 2014 John Wiley & Sons, Ltd.

  9. Biotransformation of carbon dioxide in bioelectrochemical systems: State of the art and future prospects

    NASA Astrophysics Data System (ADS)

    Bajracharya, Suman; Srikanth, Sandipam; Mohanakrishna, Gunda; Zacharia, Renju; Strik, David PBTB; Pant, Deepak

    2017-07-01

    Carbon dioxide (CO2) utilization/recycling for the production of chemicals and gaseous/liquid energy-carriers is a way to moderate the rising CO2 in the atmosphere. One of the possible solutions for the CO2 sequestration is the electrochemical reduction of this stable molecule to useful fuel/products. Nevertheless, the surface chemistry of CO2 reduction is a challenge due to the presence of large energy barriers, requiring noticeable catalysis. The recent approach of microbial electrocatalysis of CO2 reduction has promising prospects to reduce the carbon level sustainably, taking full advantage of CO2-derived chemical commodities. We review the currently investigated bioelectrochemical approaches that could possibly be implemented to enable the handling of CO2 emissions. This review covers the most recent advances in the bioelectrochemical approaches of CO2 transformations in terms of biocatalysts development and process design. Furthermore, the extensive research on carbon fixation and conversion to different value added chemicals is reviewed. The review concludes by detailing the key challenges and future prospects that could enable economically feasible microbial electrosynthesis technology.

  10. Prospective and retrospective episodic metamemory in posttraumatic stress disorder.

    PubMed

    Sacher, Mathilde; Tudorache, Andrei-Cristian; Clarys, David; Boudjarane, Mohamed; Landré, Lionel; El-Hage, Wissam

    2018-03-14

    Posttraumatic stress disorder (PTSD) has been consistently associated with episodic memory deficits. To some extent, these deficits could be related to an impairment of metamemory in individuals with PTSD. This research consequently aims at investigating prospective (feeling-of-knowing, FOK) and retrospective (confidence) metamemory judgments for episodic information in PTSD. Twenty participants with PTSD and without depression were compared to 30 healthy comparison participants on metamemory judgments during an episodic memory task. The concordance between metamemory judgments and recognition performance was then assessed by gamma correlations. The results confirmed that PTSD is associated with episodic memory impairment. Regarding metamemory, gamma correlations indicated that participants with PTSD failed to accurately predict their future memory performance as compared to the comparison group (mean FOK gamma correlations: .23 vs. .42, respectively). Furthermore, participants with PTSD made less accurate confidence judgments than comparison participants (mean confidence gamma correlations: .62 vs. .74, respectively). Our results demonstrate an alteration of both prospective and retrospective metamemory processes in PTSD, which could be of particular relevance to future therapeutic interventions focusing on metacognitive strategies.

  11. Thorium: Issues and prospects in Malaysia

    NASA Astrophysics Data System (ADS)

    AL-Areqi, Wadeeah M.; Majid, Amran Ab.; Sarmani, Sukiman; Bahri, Che Nor Aniza Che Zainul

    2015-04-01

    In Malaysia, thorium exists in minerals and rare earth elements production residue. The average range of thorium content in Malaysian monazite and xenotime minerals was found about 70,000 and 15,000 ppm respectively. About 2,636 tonnes of Malaysian monazite was produced for a period of 5 years (2006-2010) and based on the above data, it can be estimated that Malaysian monazite contains about 184.5 tonnes of thorium. Although thorium can become a major radiological problem to our environment, but with the significant deposit of thorium in Malaysian monazite, it has a prospect as a future alternative fuel in nuclear technology. This paper will discuss the thorium issues in Malaysia especially its long term radiological risks to public health and environment at storage and disposal stages, the prospect of exploring and producing high purity thorium from our rare earth elements minerals for future thorium based reactor. This paper also highlights the holistic approach in thorium recovery from Malaysian rare earth element production residue to reduce its radioactivity and extraction of thorium and rare earth elements from the minerals with minimum radiological impact to health and environment.

  12. Current progress and future prospect of microalgal biomass harvest using various flocculation technologies.

    PubMed

    Wan, Chun; Alam, Md Asraful; Zhao, Xin-Qing; Zhang, Xiao-Yue; Guo, Suo-Lian; Ho, Shih-Hsin; Chang, Jo-Shu; Bai, Feng-Wu

    2015-05-01

    Microalgae have been extensively studied for the production of various valuable products. Application of microalgae for the production of renewable energy has also received increasing attention in recent years. However, high cost of microalgal biomass harvesting is one of the bottlenecks for commercialization of microalgae-based industrial processes. Considering harvesting efficiency, operation economics and technological feasibility, flocculation is a superior method to harvest microalgae from mass culture. In this article, the latest progress of various microalgal cell harvesting methods via flocculation is reviewed with the emphasis on the current progress and prospect in environmentally friendly bio-based flocculation. Harvesting microalgae through bio-based flocculation is a promising component of the low-cost microalgal biomass production technology. Copyright © 2014 Elsevier Ltd. All rights reserved.

  13. Polycystic ovary syndrome and adverse pregnancy outcomes: Current state of knowledge, challenges and potential implications for practice.

    PubMed

    Bahri Khomami, Mahnaz; Boyle, Jacqueline A; Tay, Chau T; Vanky, Eszter; Teede, Helena J; Joham, Anju E; Moran, Lisa J

    2018-06-01

    Although there is a growing body of literature reporting that pregnancies in women with polycystic ovary syndrome (PCOS) are associated with greater complications than those without PCOS, methodological differences across studies make these results difficult to consolidate. This narrative review outlines potential mechanisms involved in adverse pregnancy outcomes in PCOS and the nature of the complications. It covers limitations of current evidence and future research directions. Future research should include prospective studies with phenotypic stratification of PCOS and matching or consideration of specific PCOS manifestations and risk factors specific to each pregnancy complication. This review also emphasizes the importance of following a healthy lifestyle for women with PCOS and of individualized care according to overall risk factors for pregnancy complications. © 2018 John Wiley & Sons Ltd.

  14. Deaf clubs today: do they still have a role to play? The cases of Cyprus and Greece.

    PubMed

    Hadjikakou, Kika; Nikolaraizi, Magda

    2011-01-01

    The present study investigated the current functions of Deaf clubs in Cyprus and in Greece. The researchers conducted in-depth semistructured interviews with 24 Cypriot and 22 Greek deaf individuals ages 19-54 years. The researchers found that the Deaf clubs in both countries provide a gathering place for deaf people, organize social and sport activities, and promote their demands through legislation. In addition, Deaf clubs maintain and transmit Deaf culture and history to future generations, offer Deaf role models to young deaf children and their families, and provide Deaf awareness to hearing people (e.g., through sign languages classes). The study participants also stressed the role of Deaf clubs in deaf people's lives, unity, and prospects for future progress.

  15. Heart Failure in Minority Populations - Impediments to Optimal Treatment in Australian Aborigines

    PubMed Central

    Iyngkaran, Pupalan; Kangaharan, Nadarajan; Zimmet, Hendrik; Arstall, Margaret; Minson, Rob; Thomas, Merlin C.; Bergin, Peter; Atherton, John; MacDonald, Peter; Hare, David L.; Horowitz, John D.; Ilton, Marcus

    2016-01-01

    Chronic heart failure (CHF) among Aboriginal/Indigenous Australians is endemic. There are also grave concerns for outcomes once acquired. This point is compounded by a lack of prospective and objective studies to plan care. To capture the essence of the presented topic it is essential to broadly understand Indigenous health. Key words such as ‘worsening’, ‘gaps’, ‘need to do more’, ‘poorly studied’, or ‘future studies should inform’ occur frequently in contrast to CHF research for almost all other groups. This narrative styled opinion piece attempts to discuss future directions for CHF care for Indigenous Australians. We provide a synopsis of the problem, highlight the treatment gaps, and define the impediments that present hurdles in optimising CHF care for Indigenous Australians. PMID:27280307

  16. Burnout during nursing education predicts lower occupational preparedness and future clinical performance: a longitudinal study.

    PubMed

    Rudman, Ann; Gustavsson, J Petter

    2012-08-01

    Early-career burnout among nurses can influence health and professional development, as well as quality of care. However, the prospective occupational consequences of study burnout have not previously been investigated in a national sample using a longitudinal design. To prospectively monitor study burnout for a national sample of nursing students during their years in higher education and at follow-up 1 year post graduation. Further, to relate the possible development of study burnout to prospective health and life outcomes, as well as student and occupational outcomes. A longitudinal cohort of Swedish nursing students (within the population-based LANE (Longitudinal Analysis of Nursing Education/Entry) study) from all sites of education in Sweden was surveyed annually. Data were collected at four points in time over 4 years: three times during higher education and 1 year post graduation. : A longitudinal sample of 1702 respondents was prospectively followed from late autumn 2002 to spring 2006. Mean level changes of study burnout (as measured by the Oldenburg Burnout Inventory, i.e. the Exhaustion and Disengagement subscales) across time, as well as prospective effects of baseline study burnout and changes in study burnout levels, were estimated using Latent Growth Curve Modeling. An increase in study burnout (from 30% to 41%) across 3 years in higher education was found, and levels of both Exhaustion and Disengagement increased significantly across the years in education (p<0.001). Baseline levels, as well as development of study burnout, predicted lower levels of in-class learner engagement and occupational preparedness in the final year. At follow-up 1 year post graduation, earlier development of study burnout was related to lower mastery of occupational tasks, less research utilization in everyday clinical practice and higher turnover intentions. The results suggest that study burnout may have interfered with learning and psychological well-being. Aspects related to work skills and intention to leave the profession were also affected. Thus, burnout development during higher education may be an important concern, and effective preventive measures to counteract burnout development may be necessary already at the outset of nursing education. Copyright © 2012 Elsevier Ltd. All rights reserved.

  17. Mechanism and active variety of allelochemicals

    USGS Publications Warehouse

    Peng, S.-L.; Wen, J.; Guo, Q.-F.

    2004-01-01

    This article summarizes allelochemicals' active variety, its potential causes and function mechanisms. Allelochemicals' activity varies with temperature, photoperiod, water and soils during natural processes, with its initial concentration, compound structure and mixed degree during functional processes, with plant accessions, tissues and maturity within-species, and with research techniques and operation processes. The prospective developmental aspects of allelopathy studies in the future are discussed. Future research should focus on: (1) to identify and purify allelochemicals more effectively, especially for agriculture, (2) the functions of allelopathy at the molecular structure level, (3) using allelopathy to explain plant species interactions, (4) allelopathy as a driving force of succession, and (5) the significance of allelopathy in the evolutionary processes.

  18. Association between background exposure to organochlorine pesticides and the risk of cognitive impairment: A prospective study that accounts for weight change.

    PubMed

    Lee, Duk-Hee; Lind, P Monica; Jacobs, David R; Salihovic, Samira; van Bavel, Bert; Lind, Lars

    2016-01-01

    Background exposure to organochlorine (OC) pesticides was recently linked to cognitive impairment and dementia in cross-sectional and case-control studies. This prospective study was performed to evaluate if OC pesticides at baseline are associated with the future risk of cognitive impairment in elderly, with particular focus on weight change. Plasma concentrations of 3 OC pesticides (p,p'-DDE, trans-nonachlor, and hexachlorobenzene) were measured among 989 men and women aged 70years in the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS). Cognitive impairment was validated by reviewing medical records. During the ten year follow-up, cognitive impairment was developed in 75 subjects. When weight change from age 70 to 75 was considered in analyses, elderly with incident cases before age 75 were excluded to keep the prospective perspective, leaving 795 study subjects and 44 incident cases. The summary measure of 3 OC pesticides predicted the development of cognitive impairment after adjusting for covariates, including weight change. Compared to subjects with OC pesticides <25th percentile, adjusted hazard ratios (HRs) in those with 25th-<75th and ≥75th percentiles were 3.5 (95% confidence interval: 1.5-8.5) and 3.2 (1.1-7.6), respectively (Ptrend=0.04). Among 506 subjects who maintained or gained body weight, adjusted HRs were 6.9 and 11.6 (1.4-92.6) among the elderly in the 25th-<75th and ≥75th percentiles compared to <25th percentile (Ptrend<0.01). This prospective study demonstrates that background exposure to OC pesticides are linked to the risk of developing cognitive impairment in elderly. The role of the chronic exposure to low dose OC pesticides in the development of dementia should be further evaluated in other populations. Copyright © 2016 Elsevier Ltd. All rights reserved.

  19. Superconductivity up to 114 K in the Bi-Al-Ca-Sr-Cu-O compound system without rare-earth elements

    NASA Technical Reports Server (NTRS)

    Chu, C. W.; Bechtold, J.; Gao, L.; Hor, P. H.; Huang, Z. J.

    1988-01-01

    Stable superconductivity up to 114 K has been reproducibly detected in Bi-Al-Ca-Sr-Cu-O multiphase systems without any rare-earth elements. Pressure has only a slight positive effect on T(c). These observations provide an extra material base for the study of the mechanism of high-temperature superconductivity and also the prospect of reduced material cost for future applications of superconductivity.

  20. Chlorine dioxide water disinfection: a prospective epidemiology study

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Michael, G.E.; Miday, R.K.; Bercz, J.P.

    An epidemiologic study of 198 persons exposed for 3 months to drinking water disinfected with chlorine dioxide was conducted in a rural village. A control population of 118 nonexposed persons was also studied. Pre-exposure hematologic and serum chemical parameters were compared with test results after 115 days of exposure. Chlorite ion levels in the water averaged approximately 5 ppM during the study period. Statistical analysis (ANOVA) of the data failed to identify any significant exposure-related effects. This study suggests that future evaluations of chlorine dioxide disinfection should be directed toward populations with potentially increased sensitivity to hemolytic agents.

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