Community-level climate change vulnerability research: trends, progress, and future directions

NASA Astrophysics Data System (ADS)

McDowell, Graham; Ford, James; Jones, Julie

2016-03-01

This study systematically identifies, characterizes, and critically evaluates community-level climate change vulnerability assessments published over the last 25 years (n = 274). We find that while the field has advanced considerably in terms of conceptual framing and methodological approaches, key shortcomings remain in how vulnerability is being studied at the community-level. We argue that vulnerability research needs to more critically engage with the following: methods for evaluating future vulnerability, the relevance of vulnerability research for decision-making, interdependencies between social and ecological systems, attention to researcher / subject power dynamics, critical interpretation of key terms, and consideration of the potentially positive opportunities presented by a changing climate. Addressing these research needs is necessary for generating knowledge that supports climate-affected communities in navigating the challenges and opportunities ahead.

Communicative Language Testing: Current Issues and Future Research

ERIC Educational Resources Information Center

Harding, Luke

2014-01-01

This article discusses a range of current issues and future research possibilities in Communicative Language Testing (CLT) using, as its departure point, the key questions which emerged during the CLT symposium at the 2010 Language Testing Forum. The article begins with a summary of the 2010 symposium discussion in which three main issues related…

A Review of Research on Metacognition in Science Education: Current and Future Directions

ERIC Educational Resources Information Center

Zohar, Anat; Barzilai, Sarit

2013-01-01

The goal of this study is to map the current state of research in the field of metacognition in science education, to identify key trends, and to discern areas and questions for future research. We conducted a systematic analysis of 178 studies published in peer-reviewed journals in the years 2000-2012 and indexed in the ERIC database. The…

Analysis of the EPSRC Principles of Robotics in regard to key research topics

NASA Astrophysics Data System (ADS)

Gning, A.; Davis, D. N.; Cheng, Y.; Robinson, P.

2017-07-01

In this paper, we review the five rules published in EPSRC Principles of Robotics with a specific focus on future robotics research topics. It is demonstrated through a pictorial representation of the five rules that these rules are questionably not sufficient, overlapping and not explicitly reflecting the true challenges of robotics ethics in relation to the future of robotics research.

Principles for research on ethnicity and health: the Leeds Consensus Statement.

PubMed

Mir, Ghazala; Salway, Sarah; Kai, Joe; Karlsen, Saffron; Bhopal, Raj; Ellison, George Th; Sheikh, Aziz

2013-06-01

There is substantial evidence that health and health-care experiences vary along ethnic lines and the need to understand and tackle ethnic health inequalities has repeatedly been highlighted. Research into ethnicity and health raises ethical, theoretical and methodological issues and, as the volume of research in this area grows, so too do concerns regarding its scientific rigour and reporting, and its contribution to reducing inequalities. Guidance may be helpful in encouraging researchers to adopt standard practices in the design, conduct and reporting of research. However, past efforts at introducing such guidance have had limited impact on research practice, and the diversity of disciplinary perspectives on the key challenges and solutions may undermine attempts to derive and promote guiding principles. A consensus building Delphi exercise--the first of its kind in this area of research practice--was undertaken with leading academics, practitioners and policymakers from a broad range of disciplinary backgrounds to assess whether consensus on key principles could be achieved. Ten key principles for conducting research on ethnicity and health emerged, covering: the aims of research in this field; how such research should be framed and focused; key design-related considerations; and the direction of future research. Despite some areas of dispute, participants were united by a common concern that the generation and application of research evidence should contribute to better health-care experiences and health outcomes for minority ethnic people. The principles provide a strong foundation to guide future ethnicity-related research and build a broader international consensus.

MycoKey round table discussions of future directions in research on chemical detection methods, genetics and biodiversity of mycotoxins

USDA-ARS?s Scientific Manuscript database

MycoKey, an EU-funded Horizon 2020 project, includes a series of “Roundtable Discussions” to gather information on trending research areas in the field of mycotoxicology. This presentation includes summaries of the Roundtable Discussions on the role of Genetics and Biodiversity in mycotoxin product...

Flight demonstrator concept for key technologies enabling future reusable launch vehicles

NASA Astrophysics Data System (ADS)

Ishimoto, Shinji; Fujii, Kenji; Mori, Takeshi

2005-07-01

A research center in JAXA has recently started research on reusable launch vehicles according to its plan placing emphasis on advanced launch technology. It is planned to demonstrate key technologies using a rocket-powered winged vehicle, and concept studies on the flight demonstrator have been conducted. This paper describes the present research plan and introduces the most compact vehicle concept among some versions under consideration.

A systematic literature review of engineering identity: definitions, factors, and interventions affecting development, and means of measurement

NASA Astrophysics Data System (ADS)

Morelock, John R.

2017-11-01

Studies exploring what it means to be an engineer professionally have been conducted for decades, but have boomed in recent years. This systematic literature review aims to organise extant studies on engineering identity by coding around four key variables: (a) definitions of engineering identity, (b) factors affecting engineering identity development, (c) interventions affecting engineering identity development, and (d) means of measuring identity. In doing so, this review provides strategies for future research and educational interventions to advance work related to engineering identity. Publications were selected for inclusion by screening and appraising results obtained from databases and keywords refined through a scoping study. Derived from key findings, suggestions for future research include bridging disparate strands of engineering identity literature and incorporating more varied methodological approaches. Also from key findings, suggestions for future practice involve better connecting existing definitions of engineering identity and factors known to affect identity development with identity-related interventions.

Baseline Bone Mineral Density Measurements Key to Future Testing Intervals

MedlinePlus

... Roundtable Focuses on Psoriatic Arthritis Research (scroll to fourth item) Spotlight on Research | April 7, 2017 Socially ... 2017 NIAMS Hosts Fellows for Symposium (scroll to fourth item) Spotlight on Research | March 24, 2017 Sex- ...

Video Feedback in Key Word Signing Training for Preservice Direct Support Staff

ERIC Educational Resources Information Center

Rombouts, Ellen; Meuris, Kristien; Maes, Bea; De Meyer, Anne-Marie; Zink, Inge

2016-01-01

Purpose: Research has demonstrated that formal training is essential for professionals to learn key word signing. Yet, the particular didactic strategies have not been studied. Therefore, this study compared the effectiveness of verbal and video feedback in a key word signing training for future direct support staff. Method: Forty-nine future…

Wildland fire research: Future Search conference notes

Treesearch

Jim Saveland; Dave Thomas

1998-01-01

This conference provided an arena for identifying common key issues that are shaping wildland fire research. Commonly identified desired outcomes include: research, integrated across disciplines, and management form partnerships; communication between management and research is effective and continuous; responsive and proactive research balances long-term scientific...

Participation under the Spotlight: Defining Future Directions. Key Players Workshop, November 2007. Report and Action Plan

ERIC Educational Resources Information Center

Cleaver, Elizabeth; Kerr, David

2007-01-01

There is an increasing emphasis on seeking and using the views of children and young people in research, evaluation and consultation. This question was at the centre of a day-long event of presentations and workshops organized by the National Foundation for Education Research in November 2007. Key objectives for the workshop included. (1) Review…

GOALS AND CURRENT RESEARCH OF EPA'S STREAM RESTORATION RESEARCH PROGRAM

EPA Science Inventory

The US EPA is involved in ongoing research on stream and riparian restoration. This presentation is designed to discuss current EPA research efforts, identify key issues in the science and practice of stream restoration, and to help frame a future National Research Council study...

The Blue Dot Workshop: Spectroscopic Search for Life on Extrasolar Planets

NASA Technical Reports Server (NTRS)

Des Marais, David J. (Editor)

1997-01-01

This workshop explored the key questions and challenges associated with detecting life on an extrasolar planet. The final product will be a NASA Conference Publication which includes the abstracts from 21 talks, summaries of key findings, and recommendations for future research. The workshop included sessions on three related topics: the biogeochemistry of biogenic gases in the atmosphere, the chemistry and spectroscopy of planetary atmospheres, and the remote sensing of planetary atmospheres and surfaces. With the observation that planetary formation is probably a common phenomenon, together with the advent of the technical capability to locate and describe extrasolar planets, this research area indeed has an exciting future.

Synthesis of discipline-based education research in physics

NASA Astrophysics Data System (ADS)

Docktor, Jennifer L.; Mestre, José P.

2014-12-01

This paper presents a comprehensive synthesis of physics education research at the undergraduate level. It is based on work originally commissioned by the National Academies. Six topical areas are covered: (1) conceptual understanding, (2) problem solving, (3) curriculum and instruction, (4) assessment, (5) cognitive psychology, and (6) attitudes and beliefs about teaching and learning. Each topical section includes sample research questions, theoretical frameworks, common research methodologies, a summary of key findings, strengths and limitations of the research, and areas for future study. Supplemental material proposes promising future directions in physics education research.

Monitoring the Future National Survey Results on Drug Use, 1975-2014: Overview, Key Findings on Adolescent Drug Use

ERIC Educational Resources Information Center

Johnston, Lloyd D.; O'Malley, Patrick M.; Miech, Richard A.; Bachman, Jerald G.; Schulenberg, John E.

2015-01-01

Monitoring the Future (MTF) is a long-term study of American adolescents, college students, and adult high school graduates through age 55. It has been conducted annually by the University of Michigan's Institute for Social Research since its inception in 1975 and is supported under a series of investigator-initiated, competing research grants…

Monitoring the Future National Survey Results on Drug Use, 1975-2015: Overview, Key Findings on Adolescent Drug Use

ERIC Educational Resources Information Center

Johnston, Lloyd D.; O'Malley, Patrick M.; Miech, Richard A.; Bachman, Jerald G.; Schulenberg, John E.

2016-01-01

Monitoring the Future (MTF) is a long-term study of American adolescents, college students, and adult high school graduates through age 55. It has been conducted annually by the University of Michigan's Institute for Social Research since its inception in 1975 and is supported under a series of investigator-initiated, competitive research grants…

Monitoring the Future National Survey Results on Drug Use, 1975-2016: Overview, Key Findings on Adolescent Drug Use

ERIC Educational Resources Information Center

Johnston, Lloyd D.; O'Malley, Patrick M.; Miech, Richard A.; Bachman, Jerald G.; Schulenberg, John E.

2017-01-01

Monitoring the Future (MTF) is a long-term study of American adolescents, college students, and adult high school graduates through age 55. It has been conducted annually by the University of Michigan's Institute for Social Research since its inception in 1975 and is supported under a series of investigator-initiated, competitive research grants…

Monitoring the Future National Survey Results on Drug Use, 1975-2013: Overview, Key Findings on Adolescent Drug Use

ERIC Educational Resources Information Center

Johnston, Lloyd D.; O'Malley, Patrick M.; Miech, Richard A.; Bachman, Jerald G.; Schulenberg, John E.

2014-01-01

Monitoring the Future (MTF) is a long-term study of American adolescents, college students, and adults through age 55. It has been conducted annually by the University of Michigan's Institute for Social Research since its inception in 1975 and is supported under a series of investigator-initiated, competing research grants from the National…

Capacity Building for School Development: Current Problems and Future Challenges

ERIC Educational Resources Information Center

Ho, Dora; Lee, Moosung

2016-01-01

This article offers a theoretical discussion on the current problems and future challenges of school capacity building in early childhood education (ECE), aiming to highlight some key areas for future research. In recent years, there has been a notable policy shift from monitoring quality through inspection to improving quality through school…

Human factors measurement for future air traffic control systems.

PubMed

Langan-Fox, Janice; Sankey, Michael J; Canty, James M

2009-10-01

This article provides a critical review of research pertaining to the measurement of human factors (HF) issues in current and future air traffic control (ATC). Growing worldwide air traffic demands call for a radical departure from current ATC systems. Future systems will have a fundamental impact on the roles and responsibilities of ATC officers (ATCOs). Valid and reliable methods of assessing HF issues associated with these changes, such as a potential increase (or decrease) in workload, are of utmost importance for advancing theory and for designing systems, procedures, and training. We outline major aviation changes and how these relate to five key HF issues in ATC. Measures are outlined, compared, and evaluated and are followed by guidelines for assessing these issues in the ATC domain. Recommendations for future research are presented. A review of the literature suggests that situational awareness and workload have been widely researched and assessed using a variety of measures, but researchers have neglected the areas of trust, stress, and boredom. We make recommendations for use of particular measures and the construction of new measures. It is predicted that, given the changing role of ATCOs and profound future airspace requirements and configurations, issues of stress, trust, and boredom will become more significant. Researchers should develop and/or refine existing measures of all five key HF issues to assess their impact on ATCO performance. Furthermore, these issues should be considered in a holistic manner. The current article provides an evaluation of research and measures used in HF research on ATC that will aid research and ATC measurement.

Vocational Psychology: An Analysis and Directions for the Future.

ERIC Educational Resources Information Center

Russell, Joyce E. A.

2001-01-01

Key areas of future research in vocational psychology include changing organizational structures, changing career attitudes, diversity of career development opportunities, international focus, increasing diversity, changing nature of technology, evolving educational systems, increased entrepreneurship, work and family issues, and career-leisure…

Critical Measurement Issues in Translational Research

ERIC Educational Resources Information Center

Glasgow, Russell E.

2009-01-01

This article summarizes critical evaluation needs, challenges, and lessons learned in translational research. Evaluation can play a key role in enhancing successful application of research-based programs and tools as well as informing program refinement and future research. Discussion centers on what is unique about evaluating programs and…

Guidelines on CV networking information flow optimization for Texas.

DOT National Transportation Integrated Search

2017-03-01

Recognizing the fundamental role of information flow in future transportation applications, the research team investigated the quality and security of information flow in the connected vehicle (CV) environment. The research team identified key challe...

Video Feedback in Key Word Signing Training for Preservice Direct Support Staff.

PubMed

Rombouts, Ellen; Meuris, Kristien; Maes, Bea; De Meyer, Anne-Marie; Zink, Inge

2016-04-01

Research has demonstrated that formal training is essential for professionals to learn key word signing. Yet, the particular didactic strategies have not been studied. Therefore, this study compared the effectiveness of verbal and video feedback in a key word signing training for future direct support staff. Forty-nine future direct support staff were randomly assigned to 1 of 3 key word signing training programs: modeling and verbal feedback (classical method [CM]), additional video feedback (+ViF), and additional video feedback and photo reminder (+ViF/R). Signing accuracy and training acceptability were measured 1 week after and 7 months after training. Participants from the +ViF/R program achieved significantly higher signing accuracy compared with the CM group. Acceptability ratings did not differ between any of the groups. Results suggest that at an equal time investment, the programs containing more training components were more effective. Research on the effect of rehearsal on signing maintenance is warranted.

Monitoring the Future: National Results on Adolescent Drug Use. Overview of Key Findings, 2009. NIH Publication No. 10-7583

ERIC Educational Resources Information Center

Johnston, Lloyd D.; O'Malley, Patrick M.; Bachman, Jerald G.; Schulenberg, John E.

2010-01-01

Monitoring the Future (MTF) is a long-term study of American adolescents, college students, and adults through age 50. It has been conducted annually by the University of Michigan's Institute for Social Research since its inception in 1975. It is supported under a series of investigator-initiated, competing research grants from the National…

Monitoring the Future. National Results on Adolescent Drug Use: Overview of Key Findings, 2009. NIH Publication Number 10-7583

ERIC Educational Resources Information Center

Johnston, Lloyd D.; O'Malley, Patrick M.; Bachman, Jerald G.; Schulenberg, John E.

2010-01-01

Monitoring the Future (MTF) is a long-term study of American adolescents, college students, and adults through age 50. It has been conducted annually by the University of Michigan's Institute for Social Research since its inception in 1975. It is supported under a series of investigator-initiated, competing research grants from the National…

Autism and Pervasive Developmental Disorders

ERIC Educational Resources Information Center

Volkmar, Fred R.; Lord, Catherine; Bailey, Anthony; Schultz, Robert T.; Klin, Ami

2004-01-01

The quantity and quality of research into autism and related conditions have increased dramatically in recent years. Consequently we selectively review key accomplishments and highlight directions for future research. More consistent approaches to diagnosis and more rigorous assessment methods have significantly advanced research, although the…

A survey of life support system automation and control

NASA Technical Reports Server (NTRS)

Finn, Cory K.

1993-01-01

The level of automation and control necessary to support advanced life support systems for use in the manned space program is steadily increasing. As the length and complexity of manned missions increase, life support systems must be able to meet new space challenges. Longer, more complex missions create new demands for increased automation, improved sensors, and improved control systems. It is imperative that research in these key areas keep pace with current and future developments in regenerative life support technology. This paper provides an overview of past and present research in the areas of sensor development, automation, and control of life support systems for the manned space program, and it discusses the impact continued research in several key areas will have on the feasibility, operation, and design of future life support systems.

Using scenarios of North Slope energy and resource development to assess research and monitoring needs

NASA Astrophysics Data System (ADS)

Payne, J. F.

2016-12-01

Significant Arctic environmental and socio-economic change has been observed on the North Slope of Alaska, presenting challenges for resident communities and management agencies that need to adapt to future changes that are difficult to model or predict. Continued climate change coupled with new or modified energy development could substantially alter the landscape and ecosystem in the future. The North Slope Science Initiative (NSSI) recognized the value of using a participatory scenarios process to consider plausible future energy and resource development scenarios through the year 2040 to help identify and prioritize research and monitoring needs on the North Slope. The scenarios process engaged diverse stakeholders, including subject matter experts and local knowledge holders. Through identification and ranking of key drivers and uncertainties relevant to the focus of the study, a series of spatially explicit scenarios was developed, analyzed in terms of low, medium and high development activities. Climate change and economic factors were key drivers affecting plausible energy development scenarios. The implications from each of the scenarios were then used to identify important research and monitoring activities and their relevant spatial scales. The scenarios project identified over 40 research and monitoring needs. The top five research needs addressed data gaps and key concerns related to how the scenarios could affect: hunting and trapping on land, health and community well-being, permafrost and hydrology, marine mammal subsistence and potential marine oil spills. The use of a participatory scenarios process was essential for identifying a range of plausible energy and resource development scenarios using a framework that involved a systematic assessment of complex interacting drivers of change, consideration of key uncertainties, and transparency throughout the project.

UTM Data Working Group Demonstration 1: Final Report

NASA Technical Reports Server (NTRS)

Rios, Joseph L.; Mulfinger, Daniel G.; Smith, Irene S.; Venkatesan, Priya; Smith, David R.; Baskaran, Vijayakumar; Wang, Leo

2017-01-01

This document summarizes activities defining and executing the first demonstration of the NASA-FAA Research Transition Team (RTT) Data Exchange and Information Architecture (DEIA) working group (DWG). The demonstration focused on testing the interactions between two key components in the future UAS Traffic Management (UTM) System through a collaborative and distributed simulation of key scenarios. The summary incorporates written feedback from each of the participants in the demonstration. In addition to reporting the activities, this report also provides some insight into future steps of this working group.

Air Reserve Component: Key to the Air Force’s Future

DTIC Science & Technology

2013-03-01

REPORT TYPE STRATEGY RESEARCH PROJECT .33 3. DATES COVERED (From - To) 4. TITLE AND SUBTITLE Air Reserve Component: Key to the Air Force’s...b. ABSTRACT UU c. THIS PAGE UU 19b. TELEPHONE NUMBER (Include area code) USAWC STRATEGY RESEARCH PROJECT...RAND Corporation, Prepared for the Office of Secretary of Defense, 2008), XV. 64 T.X. Hammes, "Offshore Control: A Proposed Strategy ," Infinity

On recent advances and future research directions for computational fluid dynamics

NASA Technical Reports Server (NTRS)

Baker, A. J.; Soliman, M. O.; Manhardt, P. D.

1986-01-01

This paper highlights some recent accomplishments regarding CFD numerical algorithm constructions for generation of discrete approximate solutions to classes of Reynolds-averaged Navier-Stokes equations. Following an overview of turbulent closure modeling, and development of appropriate conservation law systems, a Taylor weak-statement semi-discrete approximate solution algorithm is developed. Various forms for completion to the final linear algebra statement are cited, as are a range of candidate numerical linear algebra solution procedures. This development sequence emphasizes the key building blocks of a CFD RNS algorithm, including solution trial and test spaces, integration procedure and added numerical stability mechanisms. A range of numerical results are discussed focusing on key topics guiding future research directions.

The Future Growth of Degree Apprenticeships

ERIC Educational Resources Information Center

Universities UK, 2016

2016-01-01

Degree apprenticeships provide an exciting development in vocational higher education and a new opportunity for universities. Universities UK (UUK) commissioned CFE Research to identify lessons and key challenges from universities involved to date and make recommendations to help ensure the future successful development of degree apprenticeships.…

Review of Studies on Pedestrian and Bicyclist Safety, 1991-2007

DOT National Transportation Integrated Search

2012-06-01

This report reviews the pedestrian and bicyclist safety research literature in print as of 2007. It summarizes and synthesizes the key studies, evaluates existing knowledge and identifies research gaps and provides recommendations for future directio...

The Vaccination Model in Psychoneuroimmunology Research: A Review.

PubMed

Whittaker, Anna C

2018-01-01

This chapter explores the reasoning behind using the vaccination model to examine the influence of psychosocial factors on immunity. It then briefly discusses the mechanics of the vaccination response and the protocols used in psychoneuroimmunology vaccine research, before giving examples from the research literature of the studies examining relationships such as the association between stress and vaccination response. It also explores the ways the vaccination model can be used to answer key questions in psychoneuroimmunology, such as the following: "Does it matter when stressful life events occur relative to when the vaccine is received?" "What are the effects of prior exposure to the antigen?" "Do other psychosocial factors influence vaccine response besides stress?" Finally, it briefly considers the mechanisms underlying psychosocial factors and vaccination response associations and the future research needed to understand these better, and indeed to use current and future knowledge to improve and enhance vaccine responses in key at-risk populations.

Enhancing the Quantitative Representation of Socioeconomic Conditions in the Shared Socio-economic Pathways (SSPs) using the International Futures Model

NASA Astrophysics Data System (ADS)

Rothman, D. S.; Siraj, A.; Hughes, B.

2013-12-01

The international research community is currently in the process of developing new scenarios for climate change research. One component of these scenarios are the Shared Socio-economic Pathways (SSPs), which describe a set of possible future socioeconomic conditions. These are presented in narrative storylines with associated quantitative drivers. The core quantitative drivers include total population, average GDP per capita, educational attainment, and urbanization at the global, regional, and national levels. At the same time there have been calls, particularly by the IAV community, for the SSPs to include additional quantitative information on other key social factors, such as income inequality, governance, health, and access to key infrastructures, which are discussed in the narratives. The International Futures system (IFs), based at the Pardee Center at the University of Denver, is able to provide forecasts of many of these indicators. IFs cannot use the SSP drivers as exogenous inputs, but we are able to create development pathways that closely reproduce the core quantitative drivers defined by the different SSPs, as well as incorporating assumptions on other key driving factors described in the qualitative narratives. In this paper, we present forecasts for additional quantitative indicators based upon the implementation of the SSP development pathways in IFs. These results will be of value to many researchers.

The Future of Clinical Education: Opportunities and Challenges from Allied Health Deans' Perspective.

PubMed

Romig, Barbara D; Tucker, Ann W; Hewitt, Anne M; O'Sullivan Maillet, Julie

2017-01-01

There is limited information and consensus on the future of clinical education and the key factors impacting allied health (AH) clinical training. AH deans identified both opportunities and challenges impacting clinical education based on a proposed educational model. From July 2013 to March 2014, 61 deans whose institutions were 2013 members of the Association of Schools of Allied Health Professions (ASAHP) participated in a three-round Delphi survey. Agreement on the relative importance of and the ability to impact the key factors was analyzed. Impact was evaluated for three groups: individual, collective, and both individual and collective deans. AH deans' responses were summarized and refined; individual items were accepted or rerated until agreement was achieved or study conclusion. Based on the deans' ratings of importance and impact, 159 key factors within 13 clinical education categories emerged as important for the future of clinical education. Agreement was achieved on 107 opportunities and 52 challenges. The Delphi technique generated new information where little existed specific to AH deans' perspectives on AH clinical education. This research supports the Key Factors Impacting Allied Health Clinical Education conceptual model proposed earlier and provides a foundation for AH deans to evaluate opportunities and challenges impacting AH clinical education and to design action plans based on this research.

Large-Eddy Simulation: Current Capabilities, Recommended Practices, and Future Research

NASA Technical Reports Server (NTRS)

Georgiadis, Nicholas J.; Rizzetta, Donald P.; Fureby, Christer

2009-01-01

This paper presents the results of an activity by the Large Eddy Simulation (LES) Working Group of the AIAA Fluid Dynamics Technical Committee to (1) address the current capabilities of LES, (2) outline recommended practices and key considerations for using LES, and (3) identify future research needs to advance the capabilities and reliability of LES for analysis of turbulent flows. To address the current capabilities and future needs, a survey comprised of eleven questions was posed to LES Working Group members to assemble a broad range of perspectives on important topics related to LES. The responses to these survey questions are summarized with the intent not to be a comprehensive dictate on LES, but rather the perspective of one group on some important issues. A list of recommended practices is also provided, which does not treat all aspects of a LES, but provides guidance on some of the key areas that should be considered.

NASA. Lewis Research Center materials research and technology: An overview

NASA Technical Reports Server (NTRS)

Grisaffe, Salvatore J.

1990-01-01

The Materials Division at the Lewis Research Center has a long record of contributions to both materials and process technology as well as to the understanding of key high-temperature phenomena. This paper overviews the division staff, facilities, past history, recent progress, and future interests.

Where are the future transit maintenance technicians coming from?

DOT National Transportation Integrated Search

2001-01-01

This report identifies and addresses many of the key factors that affect the transit maintenance technicians of today and the issues that affect their employment. Researchers assigned to this project used information and research from census data and...

An overview of NASA research on positive displacement general-aviation engines

NASA Technical Reports Server (NTRS)

Kempke, E. E., Jr.

1980-01-01

The research and technology program related to improved and advanced general aviation engines is described. Current research is directed at the near-term improvement of conventional air-cooled spark-ignition piston engines and at future alternative engine systems based on all-new spark-ignition piston engines, lightweight diesels, and rotary combustion engines that show potential for meeting program goals in the midterm and long-term future. The conventional piston engine activities involve efforts on applying existing technology to improve fuel economy, investigation of key processes to permit leaner operation and reduce drag, and the development of cost effective technology to permit flight at high-altitudes where fuel economy and safety are improved. The advanced engine concepts activities include engine conceptual design studies and enabling technology efforts on the critical or key technology items.

Luquillo Experimental Forest: Research History and Opportunities

Treesearch

Nancy L. Harris; Ariel E. Lugo; Sandra Brown; Tamara Heartsill-Scalley

2012-01-01

The goals of this Luquillo Experimental Forest: Research History and Opportunities are to synthesize the new research that has emerged from the LEF since the publication of Brown et al. (1983) into a concise summary of key research findings and to highlight opportunities for future research that will contribute to a greater understanding of the structure and function...

Present and future of astronomy in Thailand

NASA Astrophysics Data System (ADS)

Soonthornthum, Boonrucksar

2018-05-01

Investments in national astronomical facilities and human resources through the National Astronomical Research Institute of Thailand have led to the rapid growth of astronomy in Thailand. Ongoing activities in key research areas, education and outreach will lead to further sustainable development.

Priorities for Cardiovascular Outcomes Research: A Report of the National Heart, Lung, and Blood Institute's Centers for Cardiovascular Outcomes Research Working Group.

PubMed

Khazanie, Prateeti; Krumholz, Harlan M; Kiefe, Catarina I; Kressin, Nancy R; Wells, Barbara; Wang, Tracy Y; Peterson, Eric D

2017-07-01

The Centers for Cardiovascular Outcomes Research (CCORs) held a meeting to review how cardiovascular outcomes research had evolved in the decade since the National Heart, Lung, and Blood Institute 2004 working group report and to consider future directions. The conference involved representatives from governmental agencies, outcomes research thought leaders, and public and private healthcare partners. The main purposes of this meeting were to (1) advance collaborative high-yield, high-impact outcomes research; (2) identify priorities and barriers to important cardiovascular outcomes research; and (3) define future needs for the field. This report highlights the key topics covered during the meeting, including an examination of the recent history of outcomes research, an evaluation of the current academic climate, and a vision for the future of cardiovascular outcomes research. © 2017 American Heart Association, Inc.

Devising and Implementing a Suitable Graduate Education Platform for Dublin's Institute of Technology (DIT)

ERIC Educational Resources Information Center

Carton, Janet; Jerrams, Steve

2008-01-01

Graduate education platforms have received general acclaim as key components in the future structural development of third-level and fourth-level education in Europe. In Ireland the Higher Education Authority (HEA) has endorsed the restructuring of postgraduate education to incorporate the training of research students in key generic and…

America's Children and Their Families: Key Facts.

ERIC Educational Resources Information Center

Simons, Janet M.; Eng, Mary

For advocates, parents, educators, researchers, and speechmakers, this book brings together key facts and statistical data about the American family, now and in the near future. The first section provides an overview of population and demographic trends extending through the first decade of the 21st century. This overview is followed by sections…

Rhinology Future Debates, an EUFOREA Report.

PubMed

Fokkens, W J; Bachert, C; Bernal-Sprekelsen, M; Bousquet, J; Djandji, M; Dorenbaum, A; Hakimi-Mehr, D; Hendry, S; Hopkins, C; Leunig, A; Mannent, L; Mucha, D; Onerci, M; Pugin, B; Toppila-Salmi, S; Rowe, P; Seys, S F; Stimson, S; Strzembosz, A; Hellings, P W

2017-12-01

The first Rhinology Future Debates was held in Brussels in December 2016, organized by EUFOREA (European Forum for Research and Education in Allergy and Airways diseases). The purpose of these debates is to bring novel developments in the field of Rhinology to the attention of the medical, paramedical and patient community, in a highly credible and balanced context. For the first time in Rhinology, a peer to peer scientific exchange with key experts in the field of rhinology and key medical colleagues from leading industries let to a brainstorming and discussion event on a number of hot issues in Rhinology. Novel developments are presented by key experts from industry and/or key thought leaders in Rhinology, and then followed by a lively debate on the potential positioning of new developments in care pathways, the strengths and weaknesses of the novel development(s), and comparisons with existing and/or competing products, devices, and/or molecules. As all debates are recorded and distributed on-line with limited editing (www.rhinology-future.com), EUFOREA aims at maximizing the education of the target groups on novel developments, allowing a critical appraisal of the future and a more rapid implementation of promising novel tools, techniques and/or molecules in clinical practise in Europe. The next Rhinology Future debate will be held in Brussels in December 2017.

The Triad Research University or a Post 20th Century Research University Model

ERIC Educational Resources Information Center

Tadmor, Zehev

2006-01-01

In this paper, a model for the future research university is proposed, which answers some of the key challenges facing universities. It consists of three independent yet closely knitted entities: a research institute, a university teaching college and a business unit creating a "triad" structure. The possible inevitability, the advantages and…

Exploration-Related Research on ISS: Connecting Science Results to Future Missions

NASA Technical Reports Server (NTRS)

Rhatigan, Jennifer L.; Robinson, Julie A.; Sawin, Charles F.

2005-01-01

In January, 2004, the U.S. President announced The Vision for Space Exploration, and charged the National Aeronautics and Space Administration (NASA) with using the International Space Station (ISS) for research and technology targeted at supporting U.S. space exploration goals. This paper describes: What we have learned from the first four years of research on ISS relative to the exploration mission; The on-going research being conducted in this regard; and Our current understanding of the major exploration mission risks that the ISS can be used to address. Specifically, we discuss research carried out on the ISS to determine the mechanisms by which human health is affected on long-duration missions, and to develop countermeasures to protect humans from the space environment. These bioastronautics experiments are key enablers of future long duration human exploration missions. We also discuss how targeted technological developments can enable mission design trade studies. We discuss the relationship between the ultimate number of human test subjects available on the ISS to the quality and quantity of scientific insight that can be used to reduce health risks to future explorers. We discuss the results of NASA's efforts over the past year to realign the ISS research programs to support a product-driven portfolio that is directed towards reducing the major risks of exploration missions. The fundamental challenge to science on ISS is completing experiments that answer key questions in time to shape design decisions for future exploration. In this context, exploration relevant research must do more than be conceptually connected to design decisions - it must become a part of the mission design process.

A Draft Conceptual Framework of Relevant Theories to Inform Future Rigorous Research on Student Service-Learning Outcomes

ERIC Educational Resources Information Center

Whitley, Meredith A.

2014-01-01

While the quality and quantity of research on service-learning has increased considerably over the past 20 years, researchers as well as governmental and funding agencies have called for more rigor in service-learning research. One key variable in improving rigor is using relevant existing theories to improve the research. The purpose of this…

Ethics in Evaluating a Sociotechnical Intervention With Socially Isolated Older Adults.

PubMed

Waycott, Jenny; Morgans, Amee; Pedell, Sonja; Ozanne, Elizabeth; Vetere, Frank; Kulik, Lars; Davis, Hilary

2015-11-01

The purpose of this article is to consider how ethical principles can inform the effective design and implementation of technology-based interventions that aim to promote the well-being of socially isolated older adults. We evaluated a new iPad application with small groups of older adults. In this article, we reflect on the ethical issues encountered at each stage of the research process. Drawing on the ethical principles of beneficence, research merit and integrity, justice, and respect, we identify key issues to consider in the future design and implementation of social isolation interventions that use new technologies. Key issues include (a) providing sufficient support to facilitate ongoing social interactions, (b) managing older adults' expectations, (c) providing encouragement without coercion, and (d) responding to individual needs. We conclude that it is important to report on ethical challenges incurred when evaluating social isolation interventions to inform future research in this important area. © The Author(s) 2015.

Community health nursing vision for 2020: shaping the future.

PubMed

Schofield, Ruth; Ganann, Rebecca; Brooks, Sandy; McGugan, Jennifer; Dalla Bona, Kim; Betker, Claire; Dilworth, Katie; Parton, Laurie; Reid-Haughian, Cheryl; Slepkov, Marlene; Watson, Cori

2011-12-01

As health care is shifting from hospital to community, community health nurses (CHNs) are directly affected. This descriptive qualitative study sought to understand priority issues currently facing CHNs, explore development of a national vision for community health nursing, and develop recommendations to shape the future of the profession moving toward the year 2020. Focus groups and key informant interviews were conducted across Canada. Five key themes were identified: community health nursing in crisis now, a flawed health care system, responding to the public, vision for the future, and CHNs as solution makers. Key recommendations include developing a common definition and vision of community health nursing, collaborating on an aggressive plan to shift to a primary health care system, developing a comprehensive social marketing strategy, refocusing basic baccalaureate education, enhancing the capacity of community health researchers and knowledge in community health nursing, and establishing a community health nursing center of excellence.

Factors that influence career progression among postdoctoral clinical academics: a scoping review of the literature

PubMed Central

Ranieri, Veronica; Barratt, Helen; Fulop, Naomi; Rees, Geraint

2016-01-01

Background The future of academic medicine is uncertain. Concerns regarding the future availability of qualified and willing trainee clinical academics have been raised worldwide. Of significant concern is our failure to retain postdoctoral trainee clinical academics, who are likely to be our next generation of leaders in scientific discovery. Objectives To review the literature about factors that may influence postdoctoral career progression in early career clinical academics. Design This study employed a scoping review method. Three reviewers separately assessed whether the articles found fit the inclusion criteria. Data sources PubMed, Scopus, Web of Science and Google Scholar (1991–2015). Article selection The review encompassed a broad search of English language studies published anytime up to November 2015. All articles were eligible for inclusion, including research papers employing either quantitative or qualitative methods, as well as editorials and other summary articles. Data extraction Data extracted from included publications were charted according to author(s), sample population, study design, key findings, country of origin and year of publication. Results Our review identified 6 key influences: intrinsic motivation, work–life balance, inclusiveness, work environment, mentorship and availability of funding. It also detected significant gaps within the literature about these influences. Conclusions Three key steps are proposed to help support postdoctoral trainee clinical academics. These focus on ensuring that researchers feel encouraged in their workplace, involved in collaborative dialogue with key stakeholders and able to access reliable information regarding their chosen career pathway. Finally, we highlight recommendations for future research. PMID:27798036

The Future of Australian Apprenticeships: Report of the Stakeholder Forum. Summary Report

ERIC Educational Resources Information Center

Couldrey, Margo; Loveder, Phil

2017-01-01

"The future of Australian Apprenticeships" stakeholder forum was hosted by the National Centre for Vocational Education Research (NCVER) in conjunction with the Australian Government Department of Education and Training in Canberra on 25 October, 2016. The forum was attended by over 60 key stakeholders from across the vocational…

Show Me the Way: Future Faculty Prefer Directive Feedback When Trying Active Learning Approaches

ERIC Educational Resources Information Center

Stephens, Jessica D.; Battle, David C.; Gormally, Cara L.; Brickman, Peggy

2017-01-01

Early training opportunities for future faculty, namely graduate students and postdoctoral researchers, can better prepare them to use active learning approaches. We know that instructional feedback supports sustained change and motivates instructors to improve teaching practices. Here, we incorporate feedback as a key component of a pedagogical…

Flexible Pedagogies: Technology-Enhanced Learning. Flexible Pedagogies: Preparing for the Future Series

ERIC Educational Resources Information Center

Gordon, Neil

2014-01-01

This publication is part of our five-strand research project "Flexible Pedagogies: preparing for the future". It focuses on a better understanding of technology-enhanced learning (TEL) and: (1) identifies key international drivers in the move towards technology-enhanced learning; (2) highlights some of the challenges and opportunities…

Developing Future Leaders: The Role of Reflection in the Classroom

ERIC Educational Resources Information Center

Roberts, Cynthia

2008-01-01

Leadership development continues to be a topic of conversation, education, and research. Reflection has been named as one of the key competencies needed for effective leaders particularly as the workplace grows more complex and multicultural. But how does one develop reflective skill in college students, the leaders of the future? This paper…

Research on Self-Determination in Physical Education: Key Findings and Proposals for Future Research

ERIC Educational Resources Information Center

Van den Berghe, Lynn; Vansteenkiste, Maarten; Cardon, Greet; Kirk, David; Haerens, Leen

2014-01-01

Background: During the last 30 years, several theories of motivation have generated insights into the motives underlying learners' behavior in physical education. Self-determination theory (SDT), a general theory on social development and motivation, has enjoyed increasing popularity in physical education research during the past decade. SDT…

Research Universities and the Future of America

ERIC Educational Resources Information Center

Duderstadt, James J.

2012-01-01

The crucial importance of the research university as a key asset in achieving economic prosperity and security is widely understood, as evidenced by the efforts that nations around the globe are making to create and sustain institutions of world-class quality. Yet, while America's research universities remain the strongest in the world, they are…

Canadian patient played key role in uncovering secrets about early-onset Alzheimer's disease.

PubMed Central

Lyttle, J

1996-01-01

Last June, the University of Toronto announced that Canadian scientists and a team of international researchers had discovered the gene responsible for most cases of early-onset Alzheimer's disease. One of the key players in that discovery had died just 3 months earlier. Frances Hodge, who participated in a battery of tests for the 20 years she lived with the disease, helped lead researchers to gene S182--and an ember of hope for future generations. Images p906-a PMID:8634971

Composites research at NASA Lewis Research Center

NASA Technical Reports Server (NTRS)

Levine, Stanley R.; Duffy, Stephen; Vary, Alex; Nathal, Michael V.; Miner, Robert V.; Arnold, Steven M.; Castelli, Michael G.; Hopkins, Dale A.; Meador, Michael A.

1994-01-01

Composites research at NASA Lewis is focused on their applications in aircraft propulsion, space propulsion, and space power, with the first being predominant. Research on polymer-, metal-, and ceramic-matrix composites is being carried out from an integrated materials and structures viewpoint. This paper outlines some of the topics being pursued from the standpoint of key technical issues, current status, and future directions.

Research Strategy 2002-5. Influencing the Future: Informing Policy and Improving Practice through Research.

ERIC Educational Resources Information Center

Dewsbury, Angela, Ed.

England's Learning and Skills Research Centre (LSRC) is working to build a strong body of evidence from rigorous research that is focused on critical and innovative thinking and models and solutions for the long-term development of post-16 learning. In 2002-2005, the LSRC will focus on the following activities and goals: identify key priorities;…

Focus on the future

NASA Technical Reports Server (NTRS)

Hanner, Martha S.

1988-01-01

An assessment is made of what was learned from Halley and recommendations are made for future directions for infrared studies of comets and supporting lab investigations. The following issues are addressed: (1) What steps can be taken to achieve consistent interpretation of Halley infrared data; (2) How successful has the Halley Watch been for infrared studies; (3) What supporting lab research is needed; (4) What are the key infrared observations needed for future comets; and (5) How do current and future NASA programs relate to comet studies.

Key Stakeholders' Perceptions of Motivators for Research Participation Among Individuals Who Are Incarcerated.

PubMed

Hanson, Bridget L; Faulkner, Sherilyn A; Brems, Christiane; Corey, Staci L; Eldridge, Gloria D; Johnson, Mark E

2015-10-01

Understanding motivations of research participants is crucial for developing ethical research protocols, especially for research with vulnerable populations. Through interviews with 92 institutional review board members, prison administrators, research ethicists, and researchers, we explored key stakeholders' perceptions of what motivates incarcerated individuals to participate in research. Primary motivators identified were a desire to contribute to society, gaining knowledge and health care, acquiring incentives, and obtaining social support. The potential for undue influence or coercion were also identified as motivators. These results highlight the need for careful analysis of what motivates incarcerated individuals to participate in research as part of developing or reviewing ethically permissible and responsible research protocols. Future research should expand this line of inquiry to directly include perspectives of incarcerated individuals. © The Author(s) 2015.

Lewis materials research and technology: An overview

NASA Technical Reports Server (NTRS)

Grisaffe, Salvatore J.

1987-01-01

The Materials Division at the Lewis Research Center has a long record of contributions to both materials and process technology as well as to the understanding of key high-temperature phenomena. An overview of the division staff, facilities, past history, recent progress, and future interests is presented.

Intergenerational Programmes: Public Policy and Research Implications--An International Perspective.

ERIC Educational Resources Information Center

Hatton-Yeo, Alan, Ed.; Ohsako, Toshio, Ed.

This document consists of 12 papers that, together, summarize the key issues underpinning future research and policy development related to intergenerational programs (IPs). "Introduction" (Alan Hatton-Yeo) discusses the project out of which the papers developed. "A General Assessment of IP Initiatives in the Countries…

Key success factors of health research centers: A mixed method study.

PubMed

Tofighi, Shahram; Teymourzadeh, Ehsan; Heydari, Majid

2017-08-01

In order to achieve success in future goals and activities, health research centers are required to identify their key success factors. This study aimed to extract and rank the factors affecting the success of research centers at one of the medical universities in Iran. This study is a mixed method (qualitative-quantitative) study, which was conducted between May to October in 2016. The study setting was 22 health research centers. In qualitative phase, we extracted the factors affecting the success in research centers through purposeful interviews with 10 experts of centers, and classified them into themes and sub-themes. In the quantitative phase, we prepared a questionnaire and scored and ranked the factors recognized by 54 of the study samples by Friedman test. Nine themes and 42 sub-themes were identified. Themes included: strategic orientation, management, human capital, support, projects, infrastructure, communications and collaboration, paradigm and innovation and they were rated respectively as components of success in research centers. Among the 42 identified factors, 10 factors were ranked respectively as the key factors of success, and included: science and technology road map, strategic plan, evaluation indexes, committed human resources, scientific evaluation of members and centers, innovation in research and implementation, financial support, capable researchers, equipment infrastructure and teamwork. According to the results, the strategic orientation was the most important component in the success of research centers. Therefore, managers and authorities of research centers should pay more attention to strategic areas in future planning, including the science and technology road map and strategic plan.

Key success factors of health research centers: A mixed method study

PubMed Central

Tofighi, Shahram; Teymourzadeh, Ehsan; Heydari, Majid

2017-01-01

Background In order to achieve success in future goals and activities, health research centers are required to identify their key success factors. Objective This study aimed to extract and rank the factors affecting the success of research centers at one of the medical universities in Iran. Methods This study is a mixed method (qualitative-quantitative) study, which was conducted between May to October in 2016. The study setting was 22 health research centers. In qualitative phase, we extracted the factors affecting the success in research centers through purposeful interviews with 10 experts of centers, and classified them into themes and sub-themes. In the quantitative phase, we prepared a questionnaire and scored and ranked the factors recognized by 54 of the study samples by Friedman test. Results Nine themes and 42 sub-themes were identified. Themes included: strategic orientation, management, human capital, support, projects, infrastructure, communications and collaboration, paradigm and innovation and they were rated respectively as components of success in research centers. Among the 42 identified factors, 10 factors were ranked respectively as the key factors of success, and included: science and technology road map, strategic plan, evaluation indexes, committed human resources, scientific evaluation of members and centers, innovation in research and implementation, financial support, capable researchers, equipment infrastructure and teamwork. Conclusion According to the results, the strategic orientation was the most important component in the success of research centers. Therefore, managers and authorities of research centers should pay more attention to strategic areas in future planning, including the science and technology road map and strategic plan. PMID:28979733

Written Corrective Feedback from Sociocultural Theoretical Perspectives: A Research Agenda

ERIC Educational Resources Information Center

Storch, Neomy

2018-01-01

Using key constructs from sociocultural theory and activity theory, this paper outlines three broad areas of future research on written corrective feedback (WCF) that may be of interest to second language (L2) researchers and practitioners. The first area uses the constructs of the Zone of Proximal Development (ZPD) and scaffolding to assess the…

A Survey of Research Progress and Development Tendency of Attribute-Based Encryption

PubMed Central

Pang, Liaojun; Yang, Jie; Jiang, Zhengtao

2014-01-01

With the development of cryptography, the attribute-based encryption (ABE) draws widespread attention of the researchers in recent years. The ABE scheme, which belongs to the public key encryption mechanism, takes attributes as public key and associates them with the ciphertext or the user's secret key. It is an efficient way to solve open problems in access control scenarios, for example, how to provide data confidentiality and expressive access control at the same time. In this paper, we survey the basic ABE scheme and its two variants: the key-policy ABE (KP-ABE) scheme and the ciphertext-policy ABE (CP-ABE) scheme. We also pay attention to other researches relating to the ABE schemes, including multiauthority, user/attribute revocation, accountability, and proxy reencryption, with an extensive comparison of their functionality and performance. Finally, possible future works and some conclusions are pointed out. PMID:25101313

Pathogenesis of Burkholderia pseudomallei and Burkholderia mallei.

PubMed

Larsen, Joseph C; Johnson, Nathan H

2009-06-01

Burkholderia pseudomallei and mallei are biological agents of military significance. There has been significant research in recent years to develop medical countermeasures for these organisms. This review summarizes work which details aspects of the pathogenesis of B. pseudomallei and mallei and discusses key scientific questions and directions for future research.

Navigating the Bio-Politics of Childhood

ERIC Educational Resources Information Center

Lee, Nick; Motzkau, Johanna

2011-01-01

Childhood research has long shared a bio-political terrain with state agencies in which children figure primarily as "human futures". In the 20th century bio-social dualism helped to make that terrain navigable by researchers, but, as life processes increasingly become key sites of bio-political action, bio-social dualism is becoming…

Day-by-Day: Higher Education in Afghanistan

ERIC Educational Resources Information Center

Roof, David J.

2015-01-01

This paper examines higher education in Afghanistan. Based on qualitative research, including interviews with key policymakers and stakeholders, the paper examines the primary issues, challenges, progress, and future vision for higher education in the country. The research reveals that one of the most significant issues in the country in the…

Epigenetics of Addiction: Current Knowledge, Challenges, and Future Directions.

PubMed

Cecil, Charlotte A M; Walton, Esther; Viding, Essi

2016-09-01

Addiction to psychoactive substances is a debilitating condition underpinned by the interplay of genetic and environmental factors. At present, a key challenge for research is to delineate how, at a molecular level, these influences become "biologically embedded," contributing to the onset and persistence of addictive behaviors. Recently, epigenetic processes that regulate gene expression have emerged as a potential mechanism of interest. In this commentary, we discuss the relevance of epigenetics to addiction research, starting with the current state of knowledge, what challenges we have yet to overcome, and what the future may hold in terms of research methodology and translational potential.

Community treatment orders: towards a new research agenda.

PubMed

Brophy, Lisa; Edan, Vrinda; Gooding, Piers; McSherry, Bernadette; Burkett, Tatum; Carey, Sue; Carroll, Andrew; Callaghan, Sascha; Finch, Anne; Hansford, Margaret; Hanson, Sarah; Kisely, Steven; Lawn, Sharon; Light, Edwina; Maher, Sean; Patel, Gunvant; Ryan, Christopher James; Saltmarsh, Keir; Stratford, Anthony; Tellez, Juan Jose; Toko, Maggie; Weller, Penelope

2018-02-01

The aim of this study was to report on a half-day multi-stakeholder symposium on community treatment orders (CTOs) hosted by the Melbourne Social Equity Institute (MSEI), which identified research gaps and opportunities, and produced an agreed agenda for future CTO research. The MSEI convened a symposium for 22 experts in CTO research to discuss research priorities in this field in Australasia. An independent moderator elicited views and recommendations and produced a report detailing possible research projects. Research on CTOs is contentious and there is a need to gather and examine information regarding both their use and utility. Due to the complexities involved, it was agreed that research should be undertaken in partnership with persons with had lived experience of mental health problems, clinicians, policymakers and other interdisciplinary stakeholders. Five key areas for future investigation were identified. The issues and recommendations arising from the symposium should shape the scope, nature and conduct of future research directions in the field.

Retail food environments research: Promising future with more work to be done.

PubMed

Fuller, Daniel; Engler-Stringer, Rachel; Muhajarine, Nazeem

2016-06-09

As members of the scientific committee for the Food Environments in Canada conference, we reflect on the current state of food environments research in Canada. We are very encouraged that the field is growing and there have been many collaborative efforts to link researchers in Canada, including the 2015 Food Environments in Canada Symposium and Workshop. We believe there are 5 key challenges the field will need to collectively address: theory and causality; replication and extension; consideration of rural, northern and vulnerable populations; policy analysis; and intervention research. In addressing the challenges, we look forward to working together to conduct more sophisticated, complex and community-driven food environments research in the future.

Development of a strategic plan for food security and safety in the Inuvialuit Settlement Region, Canada.

PubMed

Fillion, Myriam; Laird, Brian; Douglas, Vasiliki; Van Pelt, Linda; Archie, Diane; Chan, Hing Man

2014-01-01

Current social and environmental changes in the Arctic challenge the health and well-being of its residents. Developing evidence-informed adaptive measures in response to these changes is a priority for communities, governments and researchers. To develop strategic planning to promote food security and food safety in the Inuvialuit Settlement Region (ISR), Northwest Territories (NWT), Canada. A qualitative study using group discussions during a workshop. A regional workshop gathered Inuit organizations and community representatives, university-based researchers from the Inuit Health Survey (IHS) and NWT governmental organizations. Discussions were structured around the findings from the IHS. For each key area, programs and activities were identified and prioritized by group discussion and voting. The working group developed a vision for future research and intervention, which is to empower communities to promote health, well-being and environmental sustainability in the ISR. The group elaborated missions for the region that address the following issues: (a) capacity building within communities; (b) promotion of the use of traditional foods to address food security; (c) research to better understand the linkages between diseases and contaminants in traditional foods, market foods and lifestyle choices; (d) and promotion of affordable housing. Five programs to address each key area were developed as follows: harvest support and traditional food sharing; education and promotion; governance and policy; research; and housing. Concrete activities were identified to guide future research and intervention projects. The results of the planning workshop provide a blueprint for future research and intervention projects.

Factors that influence career progression among postdoctoral clinical academics: a scoping review of the literature.

PubMed

Ranieri, Veronica; Barratt, Helen; Fulop, Naomi; Rees, Geraint

2016-10-21

The future of academic medicine is uncertain. Concerns regarding the future availability of qualified and willing trainee clinical academics have been raised worldwide. Of significant concern is our failure to retain postdoctoral trainee clinical academics, who are likely to be our next generation of leaders in scientific discovery. To review the literature about factors that may influence postdoctoral career progression in early career clinical academics. This study employed a scoping review method. Three reviewers separately assessed whether the articles found fit the inclusion criteria. PubMed, Scopus, Web of Science and Google Scholar (1991-2015). The review encompassed a broad search of English language studies published anytime up to November 2015. All articles were eligible for inclusion, including research papers employing either quantitative or qualitative methods, as well as editorials and other summary articles. Data extracted from included publications were charted according to author(s), sample population, study design, key findings, country of origin and year of publication. Our review identified 6 key influences: intrinsic motivation, work-life balance, inclusiveness, work environment, mentorship and availability of funding. It also detected significant gaps within the literature about these influences. Three key steps are proposed to help support postdoctoral trainee clinical academics. These focus on ensuring that researchers feel encouraged in their workplace, involved in collaborative dialogue with key stakeholders and able to access reliable information regarding their chosen career pathway. Finally, we highlight recommendations for future research. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

The Status of Education and Its Consequences for Educational Research: An Anthropological Exploration

ERIC Educational Resources Information Center

Scott, Catherine

2010-01-01

Education as an institution fulfils the key social functions of promulgation of knowledge and the development of future citizens. Rather than these key functions earning it respect, education and its practitioners are the targets of criticism and what Labaree calls "scorn". This article seeks to progress the work done by Labaree on the origins of…

Modulation of telomere binding proteins: a future area of research for skin protection and anti-aging target.

PubMed

Imbert, Isabelle; Botto, Jean-Marie; Farra, Claude D; Domloge, Nouha

2012-06-01

Telomere shortening is considered as one of the main characteristics of cellular aging by limiting cellular division. Besides the fundamental advances through the discoveries of telomere and telomerase, which were recognized by a Nobel Prize, telomere protection remains an essential area of research. Recently, it was evidenced that studying the cross-talks between the proteins associated with telomere should provide a better understanding of the mechanistic basis for telomere-associated aging phenotypes. In this review, we discuss the current knowledge on telomere shortening, telomerase activity, and the essential role of telomere binding proteins in telomere stabilization and telomere-end protection. This review highlights the capacity of telomere binding proteins to limit cellular senescence and to maintain skin tissue homeostasis, which is of key importance to reduce accelerated tissue aging. Future studies addressing telomere protection and limitation of DNA damage response in human skin should include investigations on telomere binding proteins. As little is known about the expression of telomere binding proteins in human skin and modulation of their expression with aging, it remains an interesting field of skin research and a key area for future skin protection and anti-aging developments. © 2012 Wiley Periodicals, Inc.

How to shine at interviews.

PubMed

Watkins, Julie

2017-04-12

An interview's success depends on careful preparation and practice. A key aspect of this is researching your future employer and becoming familiar with the values of the trust or organisation where you want to work.

Research of Trust Chain of Operating System

NASA Astrophysics Data System (ADS)

Li, Hongjiao; Tian, Xiuxia

Trust chain is one of the key technologies in designing secure operating system based on TC technology. Constructions of trust chain and trust models are analyzed. Future works in these directions are discussed.

Research activities to improve the utilization of antibiotics in Africa.

PubMed

Massele, Amos; Tiroyakgosi, Celda; Matome, Matshediso; Desta, Abayneh; Muller, Arno; Paramadhas, Bene D Anand; Malone, Brighid; Kurusa, Gobuiwang; Didimalang, Thatayaone; Moyo, Mosana; Godman, Brian

2017-02-01

There is a need to improve the rational use of antibiotics across continents including Africa. This has resulted in initiatives in Botswana including treatment guidelines and the instigation of Antibiotic Stewardship Programs (ASPs). The next steps involve a greater understanding of current antibiotic utilization and resistance patterns (AMR). This resulted in a 2-day meeting involving key stakeholders principally from Botswana to discuss key issues including AMR rates as well as ASPs in both the public and private sectors. Following this, the findings will be used to plan future studies across Africa including point prevalence studies. The findings will be presented in July 2016 at the next Medicines Utilization Research in Africa meeting will ideally serve as a basis for planning future pertinent interventional studies to enhance the rational use of antibiotics in Botswana and wider.

The future of future-oriented cognition in non-humans: theory and the empirical case of the great apes.

PubMed

Osvath, Mathias; Martin-Ordas, Gema

2014-11-05

One of the most contested areas in the field of animal cognition is non-human future-oriented cognition. We critically examine key underlying assumptions in the debate, which is mainly preoccupied with certain dichotomous positions, the most prevalent being whether or not 'real' future orientation is uniquely human. We argue that future orientation is a theoretical construct threatening to lead research astray. Cognitive operations occur in the present moment and can be influenced only by prior causation and the environment, at the same time that most appear directed towards future outcomes. Regarding the current debate, future orientation becomes a question of where on various continua cognition becomes 'truly' future-oriented. We question both the assumption that episodic cognition is the most important process in future-oriented cognition and the assumption that future-oriented cognition is uniquely human. We review the studies on future-oriented cognition in the great apes to find little doubt that our closest relatives possess such ability. We conclude by urging that future-oriented cognition not be viewed as expression of some select set of skills. Instead, research into future-oriented cognition should be approached more like research into social and physical cognition. © 2014 The Author(s) Published by the Royal Society. All rights reserved.

The future of future-oriented cognition in non-humans: theory and the empirical case of the great apes

PubMed Central

Osvath, Mathias; Martin-Ordas, Gema

2014-01-01

One of the most contested areas in the field of animal cognition is non-human future-oriented cognition. We critically examine key underlying assumptions in the debate, which is mainly preoccupied with certain dichotomous positions, the most prevalent being whether or not ‘real’ future orientation is uniquely human. We argue that future orientation is a theoretical construct threatening to lead research astray. Cognitive operations occur in the present moment and can be influenced only by prior causation and the environment, at the same time that most appear directed towards future outcomes. Regarding the current debate, future orientation becomes a question of where on various continua cognition becomes ‘truly’ future-oriented. We question both the assumption that episodic cognition is the most important process in future-oriented cognition and the assumption that future-oriented cognition is uniquely human. We review the studies on future-oriented cognition in the great apes to find little doubt that our closest relatives possess such ability. We conclude by urging that future-oriented cognition not be viewed as expression of some select set of skills. Instead, research into future-oriented cognition should be approached more like research into social and physical cognition. PMID:25267827

Key factors of clinical research network capacity building.

PubMed

Li, Guowei; Wu, Qianyu; Jin, Yanling; Vanniyasingam, Thuva; Thabane, Lehana

2018-01-01

In general, clinical research network capacity building refers to programs aimed at enhancing networks of researchers to conduct clinical research. Although in the literature there is a large body of research on how to develop and build capacity in clinical research networks, the conceptualizations and implementations remain controversial and challenging. Moreover, the experiences learnt from the past accomplishments and failures can assist in the future capacity building efforts to be more practical, effective and efficient. In this paper, we aim to provide an overview of capacity building in clinical research network by (1) identifying the key barriers to clinical research network capacity building, (2) providing insights into how to overcome those obstacles, and (3) sharing our experiences in collaborating with national and international partners to build capacity in clinical research networks. In conclusion, we have provided some insight into how to address the key factors of clinical research network capacity building and shared some empirical experiences. A successful capacity building practice requires a joint endeavor to procure sufficient resources and support from the relevant stakeholders, to ensure its efficiency, cost-effectiveness, and sustainability.

Evaluation of the need for a large primate research facility in space

NASA Technical Reports Server (NTRS)

Sulzman, F. M.

1986-01-01

In the summer of 1983, an advisory committee was organized that would be able to evaluate NASA's current and future capabilities for nonhuman primate research in space. Individuals were chosen who had experience in four key research areas: cardiovascular physiology, vestibular neurophysiology, musculo-skeletal physiology, and fluid and electrolyte balance. Recommendations of the committee to NASA are discussed.

Prevalence of Complementary and Alternative Medicine Use among U.S. College Students: A Systematic Review

ERIC Educational Resources Information Center

Nowak, Amy L. Versnik; Hale, Heidi M.

2012-01-01

Research shows that Americans are using increasing amounts of complementary and alternative medicine (CAM) and that education is a significant predictor of CAM use. The purpose of this systematic review is to summarize key research findings on CAM use rates among U.S. college students and recommend future actions for researchers and health…

Neurotransmitter release mechanisms studied in Caenorhabditis elegans.

PubMed

Barclay, Jeff W; Morgan, Alan; Burgoyne, Robert D

2012-01-01

The process of regulated exocytosis has received considerable interest as a key component of synaptic transmission. Fusion of presynaptic vesicles and the subsequent release of their neurotransmitter contents is driven by a series of interactions between evolutionarily conserved proteins. Key insights into the molecular mechanisms of vesicle fusion have come from research using genetic model systems such as the nematode worm Caenorhabditis elegans. We review here the current knowledge regarding regulated exocytosis at the C. elegans synapse and future research directions involving this model organism. Copyright © 2012 Elsevier Ltd. All rights reserved.

Exploring the Present and Projecting the Future: People with Severe Mental Illness Speaking for Themselves

ERIC Educational Resources Information Center

Vilà, Montserrat; Pallisera, Maria; Fullana, Judit

2016-01-01

The participation of people with mental illness in research is key to their empowerment and provides them with a highly meaningful experience. The aim of this article was to explore the perspectives, views and experiences of people with severe mental illness (SMI) regarding their present life and projection of the future (desires, expectations…

What are the priorities for future success in critical care research in the UK? Report from a national stakeholder meeting.

PubMed

Walsh, Tim; Brett, Stephen J

2015-11-01

Critical care in the United Kingdom is now well-established in terms of professional status, standards of clinical practice and training, and national audit through professional bodies and government representation. Research is fundamental to the further development and maturation of the specialty, to develop new therapies and technologies, more efficient and effective service organisation, and to improve patient and family experience and outcomes. Critical care research has expanded rapidly in the UK, and now has established organisations and infrastructure to share and develop ideas, through the UK Critical Care Research Forum and similar meetings. In September 2014, the Intensive Care Foundation and Critical Care Leadership Forum hosted a research colloquium to reflect, in part, on achievements, but more importantly plan for the future. With an invited list of participants the meeting explored firstly - the practical delivery of clinical research and secondly - the future financing landscape, from both academic funders' and commercial developers' perspectives. The following article summarises the important 'take home' messages from this meeting and suggests key issues for future strategy.

Dissemination and implementation of evidence based, mental health interventions in post conflict, low resource settings

PubMed Central

Tol, Wietse; Jordans, Mark; Zangana, Goran Sabir; Amin, Ahmed Mohammed; Bolton, Paul; Bass, Judith; Bonilla-Escobar, Fransisco Javier; Thornicroft, Graham

2014-01-01

The burden of mental health problems in (post)conflict low- and middle-income countries (LMIC) is substantial. Despite growing evidence for the effectiveness of selected mental health programs in conflict-affected LMIC and growing policy support, actual uptake and implementation have been slow. A key direction for future research, and a new frontier within science and practice, is Dissemination and Implementation (DI) which directly addresses the movement of evidence-based, effective health care approaches from experimental settings into routine use. This paper outlines some key implementation challenges, and strategies to address these, while implementing evidence-based treatments in conflict-affected LMIC based on the authors’ collective experiences. Dissemination and implementation evaluation and research in conflict settings is an essential new research direction. Future DI work in LMIC should include: 1) defining concepts and developing measurement tools, 2) the measurement of DI outcomes for all programming, and 3) the systematic evaluation of specific implementation strategies. PMID:28316559

Assessment of Creativity in Education

ERIC Educational Resources Information Center

Alenizi, Mogbel

2008-01-01

This article reports themes emerging from a small-scale literature review on creativity in education. The purpose of the review was to identify key themes and approaches to inform future research. The research questions are; what is creativity? Which theory of creativity is most relevant and useful? Can creativity be assessed and if so, how? The…

Creativity and Innovation: Theory, Research, and Practice

ERIC Educational Resources Information Center

Plucker, Jonathan A., Ed.

2016-01-01

Creativity and innovation are frequently mentioned as key 21st-century skills for career and life success. Indeed, recent research provides evidence that the jobs of the future will increasingly require the ability to bring creative solutions to complex problems. And creativity is often the spice of life, that little extra something that makes the…

Key Authors in Business and Management Education Research: Productivity, Topics, and Future Directions

ERIC Educational Resources Information Center

Arbaugh, J. B.; Asarta, Carlos J.; Hwang, Alvin; Fornaciari, Charles J.; Bento, Regina F.; Dean, Kathy Lund

2017-01-01

Previous studies of author productivity in business and management education (BME) research have focused on single disciplinary areas, and even single journals. This study is the first to examine the productivity of BME scholars across multiple disciplinary areas (i.e., accounting, economics, finance, information systems, management, marketing,…

Lightweight Materials for Vehicles: Needs, Goals, and Future Technologies

DTIC Science & Technology

2010-08-01

during heating, cooling, and deformation - Developing an improved understanding of the kinetics and mechanisms for tranisition Friction Stir Welding ...technology worthiness - Identify new gaps and opportunities Pre- competitive Research Solicitations and Demonstrations - Identify technology gaps...or processing . Key Technology Gaps Active Research . Gap: Microstructural damage during welding limits potential usefulness - Many

Development of the Long-Term Agro-ecosystem Research (LTAR) Network: Current status and future trends

USDA-ARS?s Scientific Manuscript database

Long-term research conducted at multiple scales is critical to assessing the effects of key long term drivers (e.g., global population growth; land-use change; increased competition for natural resources; climate variability and change) on our ability to sustain or enhance agricultural production to...

The Social Stress Model of Substance Abuse among Childbearing-Age Women: A Review of the Literature.

ERIC Educational Resources Information Center

Lindenberg, Cathy Strachan; And Others

1994-01-01

This article synthesizes current empirical evidence for the interaction between stress level, stress modification, and drug abuse. The authors analyze 13 research studies of women; and they profile consistencies and inconsistencies in the findings, provide critiques of key methodological issues, and examine implications for future research,…

A Study of Factors Affecting University Professors' Research Output: Perspectives of Taiwanese Professors

ERIC Educational Resources Information Center

Yang, Jason Cheng-Cheng

2017-01-01

Higher education in Taiwan is facing competition and challenges from the macro environment of globalization. Taiwan's key policy direction is enhancing university quality in order to respond to these future trends. Universities' international competitiveness relies on not only faculty members' teaching quality, but also their research performance.…

Research on the Efficacy of Sensory Integration Therapy: Past, Present and Future

ERIC Educational Resources Information Center

Leong, Han M.; Carter, Mark

2008-01-01

Research on the efficacy of sensory integration therapy (SIT) is addressed in this article. Initially, past key reviews of intervention studies until 1994 are considered. Subsequently, more recent studies from 1994 until 2007 are examined. Consistent with numerous previous reviews, no robust evidence supporting the efficacy of SIT was found.…

Service Learning Inputs and Outcomes in a Personal Selling Course

ERIC Educational Resources Information Center

Hagenbuch, David J.

2006-01-01

To improve the use of service learning in the marketing curriculum, Petkus (2000) recommended that future research focus on empirical studies of service learning in specific marketing courses. Personal selling represents a key component of marketing that is quite amenable to service learning, yet very little research has examined the use of…

Community-Based Review of Research Across Diverse Community Contexts: Key Characteristics, Critical Issues, and Future Directions

PubMed Central

Ford, Angela; Wat, Eric; Brayboy, Missy; Isaacs, Mei-Ling; Park, Alice; Strelnick, Hal; Seifer, Sarena D.

2015-01-01

A growing number of community-based organizations and community–academic partnerships are implementing processes to determine whether and how health research is conducted in their communities. These community-based research review processes (CRPs) can provide individual and community-level ethics protections, enhance the cultural relevance of study designs and competence of researchers, build community and academic research capacity, and shape research agendas that benefit diverse communities. To better understand how they are organized and function, representatives of 9 CRPs from across the United States convened in 2012 for a working meeting. In this article, we articulated and analyzed the models presented, offered guidance to communities that seek to establish a CRP, and made recommendations for future research, practice, and policy. PMID:25973834

Structural Framework for Flight: NASA's Role in Development of Advanced Composite Materials for Aircraft and Space Structures

NASA Technical Reports Server (NTRS)

Tenney, Darrel R.; Davis, John G., Jr.; Johnston, Norman J.; Pipes, R. Byron; McGuire, Jack F.

2011-01-01

This serves as a source of collated information on Composite Research over the past four decades at NASA Langley Research Center, and is a key reference for readers wishing to grasp the underlying principles and challenges associated with developing and applying advanced composite materials to new aerospace vehicle concepts. Second, it identifies the major obstacles encountered in developing and applying composites on advanced flight vehicles, as well as lessons learned in overcoming these obstacles. Third, it points out current barriers and challenges to further application of composites on future vehicles. This is extremely valuable for steering research in the future, when new breakthroughs in materials or processing science may eliminate/minimize some of the barriers that have traditionally blocked the expanded application of composite to new structural or revolutionary vehicle concepts. Finally, a review of past work and identification of future challenges will hopefully inspire new research opportunities and development of revolutionary materials and structural concepts to revolutionize future flight vehicles.

Medical student perceptions of research and research-orientated careers: An international questionnaire study.

PubMed

Funston, Garth; Piper, Rory J; Connell, Claire; Foden, Philip; Young, Adam M H; O'Neill, Paul

2016-10-01

Engaging and inspiring the next generation of physician-scientists at an early stage is recognised as key to ensure the future of medical research. However, little is known about medical student perceptions of research. We attempted to ascertain perceptions of research and research-orientated careers from medical students studying in different countries. An online questionnaire was developed, piloted, and promoted to medical students in various countries. 1625 responses were collected from 38 countries. Analysis was restricted to data collected from countries with >100 responses (n = 890). Less than half the respondents felt their medical school provided adequate research training. Key perceived barriers to research participation as a student included lack of time and difficulty finding mentors or projects. A significant gender disparity existed in research ambitions of students with females desiring less research involvement. The importance of barriers and satisfaction with research training differed significantly between countries. Students perceive a number of key barriers to research involvement and pursuit of research-orientated careers. Programmes designed to engage students with research should focus on overcoming identified barriers. Greater effort is needed to engage female students who report more significant barriers and less desire to follow research-orientated careers.

A systematic review of stakeholder engagement in comparative effectiveness and patient-centered outcomes research.

PubMed

Concannon, Thomas W; Fuster, Melissa; Saunders, Tully; Patel, Kamal; Wong, John B; Leslie, Laurel K; Lau, Joseph

2014-12-01

We conducted a review of the peer-reviewed literature since 2003 to catalogue reported methods of stakeholder engagement in comparative effectiveness research and patient-centered outcomes research. We worked with stakeholders before, during and after the review was conducted to: define the primary and key research questions; conduct the literature search; screen titles, abstracts and articles; abstract data from the articles; and analyze the data. The literature search yielded 2,062 abstracts. The review was conducted on 70 articles that reported on stakeholder engagement in individual research projects or programs. Reports of stakeholder engagement are highly variable in content and quality. We found frequent engagement with patients, modestly frequent engagement with clinicians, and infrequent engagement with stakeholders in other key decision-making groups across the healthcare system. Stakeholder engagement was more common in earlier (prioritization) than in later (implementation and dissemination) stages of research. The roles and activities of stakeholders were highly variable across research and program reports. To improve on the quality and content of reporting, we developed a 7-Item Stakeholder Engagement Reporting Questionnaire. We recommend three directions for future research: 1) descriptive research on stakeholder-engagement in research; 2) evaluative research on the impact of stakeholder engagement on the relevance, transparency and adoption of research; and 3) development and validation of tools that can be used to support stakeholder engagement in future work.

Future Challenges and Opportunities in Online Prescription Drug Promotion Research

PubMed Central

Southwell, Brian G.; Rupert, Douglas J.

2016-01-01

Despite increased availability of online promotional tools for prescription drug marketers, evidence on online prescription drug promotion is far from settled or conclusive. We highlight ways in which online prescription drug promotion is similar to conventional broadcast and print advertising and ways in which it differs. We also highlight five key areas for future research: branded drug website influence on consumer knowledge and behavior, interactive features on branded drug websites, mobile viewing of branded websites and mobile advertisements, online promotion and non-US audiences, and social media and medication decisions. PMID:26927597

Regenerative nanotechnology in oral and maxillofacial surgery.

PubMed

Shakib, Kaveh; Tan, Aaron; Soskic, Vukic; Seifalian, Alexander M

2014-12-01

Regenerative nanotechnology is at the forefront of medical research, and translational medicine is a challenge to both scientists and clinicians. Although there has been an exponential rise in the volume of research generated about it for both medical and surgical uses, key questions remain about its actual benefits. Nevertheless, some people think that therapeutics based on its principles may form the core of applied research for the future. Here we give an account of its current use in oral and maxillofacial surgery, and implications and challenges for the future. Copyright © 2014 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

Beyond 2013 - The Future of European Scientific Drilling Research - An introduction.

NASA Astrophysics Data System (ADS)

Camoin, G.; Stein, R.

2009-04-01

The Integrated Ocean Drilling Program (IODP) is funded for the period 2003-2013, and is now starting to plan the future of ocean drilling beyond 2013, including the development of new technologies, new emerging research fields as and the societal relevance of this programme. In this context an interdisciplinary and multinational (USA, Europe, Japan, Asian and Oceanian countries), key conference - INVEST IODP New Ventures in Exploring Scientific Targets - addressing all international IODP partners is therefore planned for September 23rd-25th 2009 in Bremen, Germany (more information at http://www.iodp.org and http://marum.de/iodp-invest.html) to discuss future directions of ocean drilling research and related aspects such as ventures with related programmes or with industry. The first critical step of INVEST is to define the scientific research goals of the second phase of the Integrated Ocean Drilling Program (IODP), which is expected to begin in late 2013. INVEST will be open to all interested scientists and students and will be the principal opportunity for the international science community to help shape the future of scientific ocean drilling. The outcome of the conference will be the base to draft a science plan in 2010 and to define new goals and strategies to effectively meet the challenges of society and future ocean drilling. The current EGU Session and the related two days workshop which will be held at the University of Vienna will specifically address the future of European scientific drilling research. The major objectives of those two events are to sharpen the European interests in the future IODP and to prepare the INVEST Conference and are therefore of prime importance to give weight to the European propositions in the program renewal processes, both on science, technology and management, and to provide the participants with information about the status/process of ongoing discussions and negotiations regarding program structure, and provide them with the expected framework (available drilling platforms and anticipated funding levels). The key items that should be addressed during the EGU Session and the workshop will especially include : (1) The future of ECORD (science, technology, management). (2) New research initiatives and emerging fields in scientific drilling (3) Relationships between IODP and other programs (e.g. ICDP, IMAGES etc). (4) Collaboration between academia and industry. (5) New technologies and the Mission Specific Platform approach.

Synthesis of qualitative research and evidence-based nursing.

PubMed

Flemming, Kate

Evidence-based nursing is central to nursing practice. Systematic reviews have played a key part in providing evidence for decision making in nursing. Traditionally, these have consisted of syntheses of randomised controlled trials. New approaches to combining research include the synthesis of qualitative research. This article discusses the development of research synthesis as a method for creating evidence of effectiveness identified in quantitative research; more effective use of primary data; enhancing the generalizability of qualitative research; the identification of future nursing research topics.

Institutional Research: Coming of Age. General Session Presentations [at the] Annual Forum [of the] Association for Institutional Research (30th, Louisville, Kentucky, May 13-16, 1990).

ERIC Educational Resources Information Center

Endo, Jean J., Ed.

Synopses of six conference presentations are provided in this pamphlet, dealing with the theme of leadership and professional standards in university settings and the influence of social and technological challenges. In "Leadership and Team Building: Key Ingredients to the Institutional Research Role of the Future," Robert L. Taylor…

Still Far from Personal Learning: Key Aspects and Emergent Topics about How Future Professionals' PLEs Are

ERIC Educational Resources Information Center

Prendes Espinosa, María Paz; Castañeda, Linda; Gutierrez, Isabel; Román, Mª del Mar

2016-01-01

The CAPPLE project is an exploratory research project that aims to analyse the PLEs of future Spanish professionals. An ad-hoc survey about their habits for learning was conducted using a sample of 2054 university students from the last year of a degree. After data collection, two main processes were carried out: (1) the analysis of some of the…

Development of a strategic plan for food security and safety in the Inuvialuit Settlement Region, Canada

PubMed Central

Fillion, Myriam; Laird, Brian; Douglas, Vasiliki; Van Pelt, Linda; Archie, Diane; Chan, Hing Man

2014-01-01

Background Current social and environmental changes in the Arctic challenge the health and well-being of its residents. Developing evidence-informed adaptive measures in response to these changes is a priority for communities, governments and researchers. Objectives To develop strategic planning to promote food security and food safety in the Inuvialuit Settlement Region (ISR), Northwest Territories (NWT), Canada. Design A qualitative study using group discussions during a workshop. Methods A regional workshop gathered Inuit organizations and community representatives, university-based researchers from the Inuit Health Survey (IHS) and NWT governmental organizations. Discussions were structured around the findings from the IHS. For each key area, programs and activities were identified and prioritized by group discussion and voting. Results The working group developed a vision for future research and intervention, which is to empower communities to promote health, well-being and environmental sustainability in the ISR. The group elaborated missions for the region that address the following issues: (a) capacity building within communities; (b) promotion of the use of traditional foods to address food security; (c) research to better understand the linkages between diseases and contaminants in traditional foods, market foods and lifestyle choices; (d) and promotion of affordable housing. Five programs to address each key area were developed as follows: harvest support and traditional food sharing; education and promotion; governance and policy; research; and housing. Concrete activities were identified to guide future research and intervention projects. Conclusions The results of the planning workshop provide a blueprint for future research and intervention projects. PMID:25147772

The Sanford Underground Research Facility at Homestake (SURF)

DOE PAGES

Lesko, K. T.

2015-03-24

The former Homestake gold mine in Lead, South Dakota is being transformed into a dedicated laboratory to pursue underground research in rare-process physics, as well as offering research opportunities in other disciplines. A key component of the Sanford Underground Research Facility (SURF) is the Davis Campus, which is in operation at the 4850-foot level (4300 m.w.e) and currently hosts three projects: the LUX dark matter experiment, the Majorana Demonstrator neutrinoless double-beta decay experiment and the Berkeley and CUBED low-background counters. Plans for possible future experiments at SURF are well underway and include long baseline neutrino oscillation experiments, future dark mattermore » experiments as well as nuclear astrophysics accelerators. Facility upgrades to accommodate some of these future projects have already started. SURF is a dedicated facility with significant expansion capability. These plans include a Generation-2 Dark Matter experiment and the US flagship neutrino experiment, LBNE.« less

Transformation of Adolescent Peer Relations in the Social Media Context: Part 2-Application to Peer Group Processes and Future Directions for Research.

PubMed

Nesi, Jacqueline; Choukas-Bradley, Sophia; Prinstein, Mitchell J

2018-04-07

As social media use becomes increasingly widespread among adolescents, research in this area has accumulated rapidly. Researchers have shown a growing interest in the impact of social media on adolescents' peer experiences, including the ways that the social media context shapes a variety of peer relations constructs. This paper represents Part 2 of a two-part theoretical review. In this review, we offer a new model for understanding the transformative role of social media in adolescents' peer experiences, with the goal of stimulating future empirical work that is grounded in theory. The transformation framework suggests that the features of the social media context transform adolescents' peer experiences by changing their frequency or immediacy, amplifying demands, altering their qualitative nature, and/or offering new opportunities for compensatory or novel behaviors. In the current paper, we consider the ways that social media may transform peer relations constructs that often occur at the group level. Our review focuses on three key constructs: peer victimization, peer status, and peer influence. We selectively review and highlight existing evidence for the transformation of these domains through social media. In addition, we discuss methodological considerations and key conceptual principles for future work. The current framework offers a new theoretical perspective through which peer relations researchers may consider adolescent social media use.

Review of the Scientific Evidence of Using Population Normative Values for Post-Concussive Computerized Neurocognitive Assessments

DTIC Science & Technology

2016-02-10

from clinical, sports , and combat concussions. Rehabilitation Research and Practice. 2012:371970. 61. Fazio VC, Lovell MR, Pardini JE, Collins MW...study conducted by Van Kampen et al in 2006 investigated the role of neurocognitive testing in athletes following sports -related mTBI. The researchers ...learned from clinical, sports , and combat concussions. Rehabilitation Research and Practice. 2012. 87. Iverson G. Key Areas for Future Research . In

Cooperative Vehicular Networking: A Survey

PubMed Central

Ahmed, Ejaz

2018-01-01

With the remarkable progress of cooperative communication technology in recent years, its transformation to vehicular networking is gaining momentum. Such a transformation has brought a new research challenge in facing the realization of cooperative vehicular networking (CVN). This paper presents a comprehensive survey of recent advances in the field of CVN. We cover important aspects of CVN research, including physical, medium access control, and routing protocols, as well as link scheduling and security. We also classify these research efforts in a taxonomy of cooperative vehicular networks. A set of key requirements for realizing the vision of cooperative vehicular networks is then identified and discussed. We also discuss open research challenges in enabling CVN. Lastly, the paper concludes by highlighting key points of research and future directions in the domain of CVN. PMID:29881331

Pathogenesis and treatment of psoriasis: exploiting pathophysiological pathways for precision medicine.

PubMed

Alwan, Wisam; Nestle, Frank O

2015-01-01

Psoriasis is a common, chronic inflammatory skin disease associated with multi-system manifestations including arthritis and obesity. Our knowledge of the aetiology of the condition, including the key genomic, immune and environmental factors, has led to the development of targeted, precision therapies that alleviate patient morbidity. This article reviews the key pathophysiological pathways and therapeutic targets and highlights future areas of interest in psoriasis research.

Deployment Family Stress: Child Neglect and Maltreatment in U.S. Army Families

DTIC Science & Technology

2009-10-01

in u.s. Army Families." The rationale for the study was based on scientific reports indicating a possible connection between the increase in rates of...greater ease of use in the future. Key Research Accomplishments a. Scientific poster presentations ("Deployment Family Stress: Child Neglect and...Community Resources Questionnaire Appendix D: Example copy of Neglect Poster Presentation 4 Appendix A KEY INFORMANT COMMUNITY RESOURCES QUESTIONNAIRE

Transportation and Aging: A Research Agenda for Advancing Safe Mobility

ERIC Educational Resources Information Center

Dickerson, Anne E.; Molnar, Lisa J.; Eby, David W.; Adler, Geri; Bedard, Michel; Berg-Weger, Marla; Classen, Sherrilene; Foley, Daniel; Horowitz, Amy; Kerschner, Helen; Page, Oliver; Silverstein, Nina M.; Staplin, Loren; Trujillo, Leonard

2007-01-01

Purpose: We review what we currently know about older driver safety and mobility, and we highlight important research needs in a number of key areas that hold promise for achieving the safety and mobility goals for the aging baby boomers and future generations of older drivers. Design and Methods: Through the use of a framework for transportation…

Research Data Management: A Library Practitioner's Perspective

ERIC Educational Resources Information Center

Yu, Siu Hong

2017-01-01

The Future Voices in Public Services column is a forum for students in graduate library and information science programs to discuss key issues they see in academic library public services, to envision what they feel librarians in public service have to offer to academia, to relate their visions for the profession, or to describe research that is…

Cardiac stem cell biology: glimpse of the past, present, and future.

PubMed

Matsa, Elena; Sallam, Karim; Wu, Joseph C

2014-01-03

Cardiac regeneration strategies and de novo generation of cardiomyocytes have long been significant areas of research interest in cardiovascular medicine. In this review, we outline a variety of common cell sources and methods used to regenerate cardiomyocytes and highlight the important role that key Circulation Research articles have played in this flourishing field.

Competencies of Front-Line Managers in Supported Accommodation: Issues for Practice and Future Research

ERIC Educational Resources Information Center

Clement, Tim; Bigby, Christine

2012-01-01

Background: Front-line managers of supported accommodation for people with intellectual disability are assumed to have a key role in the realisation of outcomes for service users. Yet, their job has been little researched. A job analysis from Minnesota that identified 142 competencies required of effective front-line managers was used to examine…

Behavioral Response Research Evaluation Workshop (BRREW)

DTIC Science & Technology

2015-09-30

future research directions, focusing on controlled exposure experiments ( captive and free-ranging animals) and observational studies. OBJECTIVES...in key areas including controlled exposure experiments ( captive and free-ranging animals) and observational studies on real Navy exercises; 2...include response to simulated sources of Navy sonar (BRS and captive studies), response to real Navy sources (BRS studies, M3R), incidental response

Marketing Education National Research Conference Report. Marketing Practices: Implications for Developing a Future Workforce. (Key West, Florida, April 15-17, 1994).

ERIC Educational Resources Information Center

Norwood, Marcella M., Ed.

This conference provided a forum for presenting research findings to educators and other audiences interested in marketing education. The following papers were presented: "Application and Utilization of the Marketing Education Baccalaureate Degree in the Public School--Training and Development Arenas" (Wyant, Prey); "The Impact of…

Clinical Research with Transcranial Direct Current Stimulation (tDCS): Challenges and Future Directions

PubMed Central

Brunoni, Andre Russowsky; Nitsche, Michael A.; Bolognini, Nadia; Bikson, Marom; Wagner, Tim; Merabet, Lotfi; Edwards, Dylan J.; Valero-Cabre, Antoni; Rotenberg, Alexander; Pascual-Leone, Alvaro; Ferrucci, Roberta; Priori, Alberto; Boggio, Paulo; Fregni, Felipe

2011-01-01

Background Transcranial direct current stimulation (tDCS) is a neuromodulatory technique that delivers low-intensity, direct current to cortical areas facilitating or inhibiting spontaneous neuronal activity. In the past ten years, tDCS physiological mechanisms of action have been intensively investigated giving support for the investigation of its applications in clinical neuropsychiatry and rehabilitation. However, new methodological, ethical, and regulatory issues emerge when translating the findings of preclinical and phase I studies into phase II and III clinical studies. The aim of this comprehensive review is to discuss the key challenges of this process and possible methods to address them. Methods We convened a workgroup of researchers in the field to review, discuss and provide updates and key challenges of neuromodulation use for clinical research. Main Findings/Discussion We reviewed several basic and clinical studies in the field and identified potential limitations, taking into account the particularities of the technique. We review and discuss the findings into four topics: (i) mechanisms of action of tDCS, parameters of use and computer-based human brain modeling investigating electric current fields and magnitude induced by tDCS; (ii) methodological aspects related to the clinical research of tDCS as divided according to study phase (i.e., preclinical, phase I, phase II and phase III studies); (iii) ethical and regulatory concerns; (iv) future directions regarding novel approaches, novel devices, and future studies involving tDCS. Finally, we propose some alternative methods to facilitate clinical research on tDCS. PMID:22037126

Abrupt Climate Change: the View from the Past, the Present and the Future

NASA Astrophysics Data System (ADS)

White, J. W. C.

2014-12-01

Climate is changing as humans put more and more greenhouse gases into the atmosphere. With CO2 levels today around 400ppm, we are clearly committed to far more climate change, both in the near term, and well beyond our children's future. A key question is how that change will occur. Abrupt climate changes are those that exceed our expectations, preparedness, and ability to adapt. Such changes challenge us economically, physically, and socially. This talk will draw upon results from ice core research over the past twenty years, as well as a new NRC report on abrupt climate change in order to address abrupt change, as seen in the past in ice cores, as seen today in key environmental systems upon which humans depend, and what is may be coming in the future.

On the Predictability of Future Impact in Science

PubMed Central

Penner, Orion; Pan, Raj K.; Petersen, Alexander M.; Kaski, Kimmo; Fortunato, Santo

2013-01-01

Correctly assessing a scientist's past research impact and potential for future impact is key in recruitment decisions and other evaluation processes. While a candidate's future impact is the main concern for these decisions, most measures only quantify the impact of previous work. Recently, it has been argued that linear regression models are capable of predicting a scientist's future impact. By applying that future impact model to 762 careers drawn from three disciplines: physics, biology, and mathematics, we identify a number of subtle, but critical, flaws in current models. Specifically, cumulative non-decreasing measures like the h-index contain intrinsic autocorrelation, resulting in significant overestimation of their “predictive power”. Moreover, the predictive power of these models depend heavily upon scientists' career age, producing least accurate estimates for young researchers. Our results place in doubt the suitability of such models, and indicate further investigation is required before they can be used in recruiting decisions. PMID:24165898

The future of pediatric dentistry education and curricula: a Chilean perspective.

PubMed

Mariño, Rodrigo; Ramos-Gómez, Francisco; Manton, David John; Onetto, Juan Eduardo; Hugo, Fernando; Feldens, Carlos Alberto; Bedi, Raman; Uribe, Sergio; Zillmann, Gisela

2016-07-18

A meeting was organised to consolidate a network of researchers and academics from Australia, Brazil, Chile, the UK and the USA, relating to Early Childhood Caries (ECC) and Dental Trauma (DT). As part of this meeting, a dedicated session was held on the future of paediatric dental education and curricula. Twenty-four paediatric dentistry (PD) academics, representing eight Chilean dental schools, and three international specialists (from Brazil and Latvia) participated in group discussions facilitated by five members of the ECC/DT International Collaborative Network. Data were collected from group discussions which followed themes developed as guides to identify key issues associated with paediatric dentistry education, training and research. Participants discussed current PD dental curricula in Chile, experiences in educating new cohorts of oral health care providers, and the outcomes of existing efforts in education and research in PD. They also, identified challenges, opportunities and areas in need of further development. This paper provides an introspective analysis of the education and training of PD in Chile; describes the input provided by participants into pediatric dentistry education and curricula; and sets out some key priorities for action with suggested directions to best prepare the future dental workforce to maximise oral health outcomes for children. Immediate priorities for action in paediatric dentistry in Chile were proposed.

Needs and Requirements for Future Research Reactors (ORNL Perspectives)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ilas, Germina; Bryan, Chris; Gehin, Jess C.

2016-02-10

The High Flux Isotope Reactor (HFIR) is a vital national and international resource for neutron science research, production of radioisotopes, and materials irradiation. While HFIR is expected to continue operation for the foreseeable future, interest is growing in understanding future research reactors features, needs, and requirements. To clarify, discuss, and compile these needs from the perspective of Oak Ridge National Laboratory (ORNL) research and development (R&D) missions, a workshop, titled “Needs and Requirements for Future Research Reactors”, was held at ORNL on May 12, 2015. The workshop engaged ORNL staff that is directly involved in research using HFIR to collectmore » valuable input on the reactor’s current and future missions. The workshop provided an interactive forum for a fruitful exchange of opinions, and included a mix of short presentations and open discussions. ORNL staff members made 15 technical presentations based on their experience and areas of expertise, and discussed those capabilities of the HFIR and future research reactors that are essential for their current and future R&D needs. The workshop was attended by approximately 60 participants from three ORNL directorates. The agenda is included in Appendix A. This document summarizes the feedback provided by workshop contributors and participants. It also includes information and insights addressing key points that originated from the dialogue started at the workshop. A general overview is provided on the design features and capabilities of high performance research reactors currently in use or under construction worldwide. Recent and ongoing design efforts in the US and internationally are briefly summarized, followed by conclusions and recommendations.« less

Career Interests of Canadian Psychiatry Residents: What Makes Residents Choose a Research Career?

PubMed Central

Laliberté, Vincent; Rapoport, Mark J.; Andrew, Melissa; Davidson, Marla

2016-01-01

Objectives: Training future clinician-researchers remains a challenge faced by Canadian psychiatry departments. Our objectives were to determine the prevalence of residents interested in pursuing research and other career options as part of their practice, and to identify the factors associated with interest in research. Method: Data from a national online survey of 207 Canadian psychiatry residents from a total of 853 (24.3% response rate) were examined. The main outcome was interest in research as part of residents’ future psychiatrist practice. Bivariate and multivariate analyses were performed to identify demographic and vocational variables associated with research interest. Results: Interest in research decreases by 76% between the first and fifth year of psychiatry residency (OR 0.76 per year, 95% CI 0.60 to 0.97). Training in a department with a residency research track did not correlate with increased research interest (χ2 = 0.007, df = 1, P = 0.93). Conclusions: Exposing and engaging psychiatry residents in research as early as possible in residency training appears key to promoting future research interest. Psychiatry residency programs and research tracks could consider emphasizing research training initiatives and protected research time early in residency. PMID:27253699

Career Interests of Canadian Psychiatry Residents: What Makes Residents Choose a Research Career?

PubMed

Laliberté, Vincent; Rapoport, Mark J; Andrew, Melissa; Davidson, Marla; Rej, Soham

2016-02-01

Training future clinician-researchers remains a challenge faced by Canadian psychiatry departments. Our objectives were to determine the prevalence of residents interested in pursuing research and other career options as part of their practice, and to identify the factors associated with interest in research. Data from a national online survey of 207 Canadian psychiatry residents from a total of 853 (24.3% response rate) were examined. The main outcome was interest in research as part of residents' future psychiatrist practice. Bivariate and multivariate analyses were performed to identify demographic and vocational variables associated with research interest. Interest in research decreases by 76% between the first and fifth year of psychiatry residency (OR 0.76 per year, 95% CI 0.60 to 0.97). Training in a department with a residency research track did not correlate with increased research interest (χ2 = 0.007, df = 1, P = 0.93). Exposing and engaging psychiatry residents in research as early as possible in residency training appears key to promoting future research interest. Psychiatry residency programs and research tracks could consider emphasizing research training initiatives and protected research time early in residency. © The Author(s) 2015.

Review of Research Status and Development Trends of Wireless Passive LC Resonant Sensors for Harsh Environments.

PubMed

Li, Chen; Tan, Qiulin; Jia, Pinggang; Zhang, Wendong; Liu, Jun; Xue, Chenyang; Xiong, Jijun

2015-06-04

Measurement technology for various key parameters in harsh environments (e.g., high-temperature and biomedical applications) continues to be limited. Wireless passive LC resonant sensors offer long service life and can be suitable for harsh environments because they can transmit signals without battery power or wired connections. Consequently, these devices have become the focus of many current research studies. This paper addresses recent research, key technologies, and practical applications relative to passive LC sensors used to monitor temperature, pressure, humidity, and harmful gases in harsh environments. The advantages and disadvantages of various sensor types are discussed, and prospects and challenges for future development of these sensors are presented.

Review of Research Status and Development Trends of Wireless Passive LC Resonant Sensors for Harsh Environments

PubMed Central

Li, Chen; Tan, Qiulin; Jia, Pinggang; Zhang, Wendong; Liu, Jun; Xue, Chenyang; Xiong, Jijun

2015-01-01

Measurement technology for various key parameters in harsh environments (e.g., high-temperature and biomedical applications) continues to be limited. Wireless passive LC resonant sensors offer long service life and can be suitable for harsh environments because they can transmit signals without battery power or wired connections. Consequently, these devices have become the focus of many current research studies. This paper addresses recent research, key technologies, and practical applications relative to passive LC sensors used to monitor temperature, pressure, humidity, and harmful gases in harsh environments. The advantages and disadvantages of various sensor types are discussed, and prospects and challenges for future development of these sensors are presented. PMID:26053753

In science communication, why does the idea of the public deficit always return? Exploring key influences.

PubMed

Suldovsky, Brianne

2016-05-01

Despite mounting criticism, the deficit model remains an integral part of science communication research and practice. In this article, I advance three key factors that contribute to the idea of the public deficit in science communication, including the purpose of science communication, how communication processes and outcomes are conceptualized, and how science and scientific knowledge are defined. Affording science absolute epistemic privilege, I argue, is the most compelling factor contributing to the continued use of the deficit model. In addition, I contend that the deficit model plays a necessary, though not sufficient, role in science communication research and practice. Areas for future research are discussed. © The Author(s) 2016.

A team approach to recruitment in hospice research: engaging patients, close people and health professionals.

PubMed

L Campbell, Cathy; Bailey, Cara; Armour, Kathy; Perry, Rachel; Orlando, Rosanna; Kinghorn, Philip; Jones, Louise; Coast, Joanna

2016-07-02

Research is vital to the future development of hospice care. However, research in hospice settings is very challenging. This paper describes a case study of a successful multidisciplinary research team approach (MDRT) to the recruitment of participants (hospice patients, family members and health professionals) for a study in a hospice setting on the economic evaluation of end-of-life care. A successful recruitment plan includes three key strategies: identifying key members of the MDRT early in the research process; having a clear and constant communication stream; and creating an environment where all team members have a shared commitment to the research, all voices are heard and valued, and everyone contributes to the research aims. An MDRT approach will be helpful to guide the development of successful recruitment plans for academic-community research partnerships in the hospice setting.

Transparent Conducting Oxides: Status and Opportunities in Basic Research

DOE Office of Scientific and Technical Information (OSTI.GOV)

Coutts, T. J.; Perkins, J. D.; Ginley, D.S.

1999-08-01

In this paper, we begin by discussing the historical background of transparent conducting oxides and then make some general remarks about their typical properties. This is followed by a short discussion of the desired properties for future applications (particularly photovoltaic devices). These are ambitious objectives but they provide targets for future basic research and development. Although it may be possible to obtain these properties in the laboratory, it is vital to ensure that account is taken of industrial perceptions to the development of the next generation of materials. Hence, we spend some time discussing industrial criteria. Next, we discuss keymore » physical properties that determine the macroscopic physical properties that, in turn, affect the performance of devices. Finally, we select several key topics that ought to be included in future basic research programs.« less

Security in the Cache and Forward Architecture for the Next Generation Internet

NASA Astrophysics Data System (ADS)

Hadjichristofi, G. C.; Hadjicostis, C. N.; Raychaudhuri, D.

The future Internet architecture will be comprised predominately of wireless devices. It is evident at this stage that the TCP/IP protocol that was developed decades ago will not properly support the required network functionalities since contemporary communication profiles tend to be data-driven rather than host-based. To address this paradigm shift in data propagation, a next generation architecture has been proposed, the Cache and Forward (CNF) architecture. This research investigates security aspects of this new Internet architecture. More specifically, we discuss content privacy, secure routing, key management and trust management. We identify security weaknesses of this architecture that need to be addressed and we derive security requirements that should guide future research directions. Aspects of the research can be adopted as a step-stone as we build the future Internet.

Future Generation Network Architecture (New Arch)

DTIC Science & Technology

2004-06-01

Laboratory/IFKF, Rome NY. Other, unfunded, participants in the project included the UC Berkeley ICSI Center for Internet Research (Mark Handley), and an...developed in the late 1970s under DARPA’s Internet research program. The global technical principles, or architecture, of the Internet design represented a...wide range of key aspects of the basic architecture, in search of unifying principles. The success of the original DARPA Internet research program

Recruitment of multiple stakeholders to health services research: lessons from the front lines.

PubMed

Kho, Michelle E; Rawski, Ellen; Makarski, Julie; Brouwers, Melissa C

2010-05-13

Self-administered surveys are an essential methodological tool for health services and knowledge translation research, and engaging end-users of the research is critical. However, few documented accounts of the efforts invested in recruitment of multiple different stakeholders to one health services research study exist. Here, we highlight the challenges of recruiting key stakeholders (policy-makers, clinicians, guideline developers) to a Canadian Institutes of Health Research (CIHR) funded health services research (HSR) study aimed to develop an updated and refined version of a guideline appraisal tool, the AGREE. Using evidence-based methods of recruitment, our goal was to recruit 192 individuals: 80 international guideline developers, 80 Canadian clinicians and 32 Canadian policy/decision-makers. We calculated the participation rate and the recruitment efficiency. We mailed 873 invitation letters. Of 838 approached, our participation rate was 29%(240) and recruitment efficiency, 19%(156). One policy-maker manager did not allow policy staff to participate in the study. Based on the results from this study, we suggest that future studies aiming to engage similar stakeholders in HSR over sample by at least 5 times to achieve their target sample size and allow for participant withdrawals. We need continued efforts to communicate the value of research between researchers and end-users of research (policy-makers, clinicians, and other researchers), integration of participatory research strategies, and promotion of the value of end-user involvement in research. Future research to understand methods of improving recruitment efficiency and engaging key stakeholders in HSR is warranted.

Gene therapy in the post-Gelsinger era.

PubMed

Smith, Lynn; Byers, Jacqueline Fowler

2002-12-01

As gene therapy research races to a first cure of a genetic-based disease, the research community has struggled with the aftermath of the well-publicized death of Jesse Gelsinger from complications of an experimental treatment. In a wrongful death lawsuit against the University of Pennsylvania and its researchers, Jesse Gelsinger's family alleged violations of federal regulations and research ethics. This article reviews gene therapy research, examines the role of the key players in this tragedy, and provides suggestions for preventing future misfortunes.

Evidence base and future research directions in the management of low back pain.

PubMed

Abbott, Allan

2016-03-18

Low back pain (LBP) is a prevalent and costly condition. Awareness of valid and reliable patient history taking, physical examination and clinical testing is important for diagnostic accuracy. Stratified care which targets treatment to patient subgroups based on key characteristics is reliant upon accurate diagnostics. Models of stratified care that can potentially improve treatment effects include prognostic risk profiling for persistent LBP, likely response to specific treatment based on clinical prediction models or suspected underlying causal mechanisms. The focus of this editorial is to highlight current research status and future directions for LBP diagnostics and stratified care.

Role of oral pre-exposure prophylaxis (PrEP) in current and future HIV prevention strategies.

PubMed

Burns, David N; Grossman, Cynthia; Turpin, Jim; Elharrar, Vanessa; Veronese, Fulvia

2014-12-01

Treatment as prevention is expected to have a major role in reducing HIV incidence, but other prevention interventions will also be required to bring the epidemic under control, particularly among key populations. One or more forms of pre-exposure prophylaxis (PrEP) will likely play a critical role. Oral PrEP with emtricitabine-tenofovir (Truvada®) is currently available in the US and some other countries, but uptake has been slow. We review the concerns that have contributed to this slow uptake and discuss current and future research in this critical area of HIV prevention research.

Training and career development in palliative care and end-of-life research: opportunities for development in the U.S.

PubMed

Aziz, Noreen M; Grady, Patricia A; Curtis, J Randall

2013-12-01

There has been a dramatic increase in attention to the field of palliative care and end-of-life (PCEOL) research over the past 20 years. This increase is particularly notable in the development of palliative care clinical and educational programs. However, there remain important shortcomings in the evidence base to ensure access to and delivery of effective palliative care for patients with life-limiting illness and their families. Development of this evidence base will require that we train the next generation of researchers to focus on issues in PCEOL. The purpose of this article was to explore the current status of the recruitment, training, and retention of future investigators in PCEOL research in the U.S. and propose recommendations to move us forward. Some key contextual issues for developing and supporting this research workforce are articulated, along with timely and important research areas that will need to be addressed during research training and career development. We provide targeted key recommendations to facilitate the nurturing and support of the future research workforce that is needed to ensure the development and implementation of the science necessary for providing high-quality, evidence-based palliative care to all who need and desire it. Copyright © 2013 U.S. Cancer Pain Relief Committee. Published by Elsevier Inc. All rights reserved.

[Landscape classification: research progress and development trend].

PubMed

Liang, Fa-Chao; Liu, Li-Ming

2011-06-01

Landscape classification is the basis of the researches on landscape structure, process, and function, and also, the prerequisite for landscape evaluation, planning, protection, and management, directly affecting the precision and practicability of landscape research. This paper reviewed the research progress on the landscape classification system, theory, and methodology, and summarized the key problems and deficiencies of current researches. Some major landscape classification systems, e. g. , LANMAP and MUFIC, were introduced and discussed. It was suggested that a qualitative and quantitative comprehensive classification based on the ideology of functional structure shape and on the integral consideration of landscape classification utility, landscape function, landscape structure, physiogeographical factors, and human disturbance intensity should be the major research directions in the future. The integration of mapping, 3S technology, quantitative mathematics modeling, computer artificial intelligence, and professional knowledge to enhance the precision of landscape classification would be the key issues and the development trend in the researches of landscape classification.

Making Computers Smarter: A Look At the Controversial Field of Artificial Intelligence.

ERIC Educational Resources Information Center

Green, John O.

1984-01-01

Defines artificial intelligence (AI) and discusses its history; the current state of the art, research, experimentation, and practical applications; and probable future developments. Key dates in the history of AI and eight references are provided. (MBR)

Attachment theory: progress and future directions.

PubMed

Fearon, R M Pasco; Roisman, Glenn I

2017-06-01

Attachment is a key subfield in the area of parenting and parent-child relationships research. In this brief overview, we summarise what we consider to be the state-of-the-art of attachment research, focusing primarily on the nature and significance of attachment in infancy and early childhood. We review 4 major topics that are central issues in the scientific literature on attachment: (1) the role of the environment in the development of attachment, (2) the intergenerational transmission of patterns of attachment, (3) the stability of attachment patterns through early adulthood, and (4) the role of attachment in adjustment and maladjustment. We conclude by highlighting several critical unresolved issues and priorities for future research. Copyright © 2017. Published by Elsevier Ltd.

Computational chemistry in pharmaceutical research: at the crossroads.

PubMed

Bajorath, Jürgen

2012-01-01

Computational approaches are an integral part of pharmaceutical research. However, there are many of unsolved key questions that limit the scientific progress in the still evolving computational field and its impact on drug discovery. Importantly, a number of these questions are not new but date back many years. Hence, it might be difficult to conclusively answer them in the foreseeable future. Moreover, the computational field as a whole is characterized by a high degree of heterogeneity and so is, unfortunately, the quality of its scientific output. In light of this situation, it is proposed that changes in scientific standards and culture should be seriously considered now in order to lay a foundation for future progress in computational research.

Transcendental Political Systems and the Gravity Model

NASA Technical Reports Server (NTRS)

Lock, Connor

2012-01-01

This summer I have been working on an Army Deep Futures Model project named Themis. Themis is a JPL based modeling framework that anticipates possible future states for the world within the next 25 years. The goal of this framework is to determine the likelihood that the US Army will need to intervene on behalf of the US strategic interests. Key elements that are modeled within this tool include the world structure and major decisions that are made by key actors. Each actor makes decisions based on their goals and within the constraints of the structure of the system in which they are located. In my research I have focused primarily on the effects of structures upon the decision-making processes of the actors within them. This research is a natural extension of my major program at Georgetown University, where I am studying the International Political Economy and the structures that make it up. My basic goal for this summer project was to be a helpful asset to the Themis modeling team, with any research done or processes learned constituting a bonus.

Surface acoustic wave devices for sensor applications

NASA Astrophysics Data System (ADS)

Bo, Liu; Xiao, Chen; Hualin, Cai; Mohammad, Mohammad Ali; Xiangguang, Tian; Luqi, Tao; Yi, Yang; Tianling, Ren

2016-02-01

Surface acoustic wave (SAW) devices have been widely used in different fields and will continue to be of great importance in the foreseeable future. These devices are compact, cost efficient, easy to fabricate, and have a high performance, among other advantages. SAW devices can work as filters, signal processing units, sensors and actuators. They can even work without batteries and operate under harsh environments. In this review, the operating principles of SAW sensors, including temperature sensors, pressure sensors, humidity sensors and biosensors, will be discussed. Several examples and related issues will be presented. Technological trends and future developments will also be discussed. Project supported by the National Natural Science Foundation of China (Nos. 60936002, 61025021, 61434001, 61574083), the State Key Development Program for Basic Research of China (No. 2015CB352100), the National Key Project of Science and Technology (No. 2011ZX02403-002) and the Special Fund for Agroscientific Research in the Public Interest of China (No. 201303107). M.A.M is additionally supported by the Postdoctoral Fellowship (PDF) program of the Natural Sciences and Engineering Research Council (NSERC) of Canada and the China Postdoctoral Science Foundation (CPSF).

The Convoy Model: Explaining Social Relations From a Multidisciplinary Perspective

PubMed Central

Antonucci, Toni C.

2014-01-01

Purpose of the Study: Social relations are a key aspect of aging and the life course. In this paper, we trace the scientific origins of the study of social relations, focusing in particular on research grounded in the convoy model. Design and Methods: We first briefly review and critique influential historical studies to illustrate how the scientific study of social relations developed. Next, we highlight early and current findings grounded in the convoy model that have provided key insights into theory, method, policy, and practice in the study of aging. Results: Early social relations research, while influential, lacked the combined approach of theoretical grounding and methodological rigor. Nevertheless, previous research findings, especially from anthropology, suggested the importance of social relations in the achievement of positive outcomes. Considering both life span and life course perspectives and grounded in a multidisciplinary perspective, the convoy model was developed to unify and consolidate scattered evidence while at the same time directing future empirical and applied research. Early findings are summarized, current evidence presented, and future directions projected. Implications: The convoy model has provided a useful framework in the study of aging, especially for understanding predictors and consequences of social relations across the life course. PMID:24142914

Greenshell™ Mussels: A Review of Veterinary Trials and Future Research Directions.

PubMed

Eason, Charles T; Adams, Serean L; Puddick, Jonathan; Romanazzi, Donato; Miller, Matthew R; King, Nick; Johns, Sarah; Forbes-Blom, Elizabeth; Hessian, Paul A; Stamp, Lisa K; Packer, Michael A

2018-03-27

The therapeutic benefits of Greenshell™ mussel (GSM; Perna canaliculus ) preparations have been studied using in vitro test systems, animal models, and human clinical trials focusing mainly on anti-inflammatory and anti-arthritic effects. Activity is thought to be linked to key active ingredients that include omega-3 polyunsaturated fatty acids, a variety of carotenoids and other bioactive compounds. In this paper, we review the studies that have been undertaken in dogs, cats, and horses, and outline new research directions in shellfish breeding and high-value nutrition research programmes targeted at enhancing the efficacy of mussel and algal extracts. The addition of GSM to animal diets has alleviated feline degenerative joint disease and arthritis symptoms, and chronic orthopaedic pain in dogs. In horses, GSM extracts decreased the severity of lameness and joint pain and provided improved joint flexion in limbs with lameness attributed to osteoarthritis. Future research in this area should focus on elucidating the key active ingredients in order to link concentrations of these active ingredients with their pharmacokinetics and therapeutic effects. This would enable consistent and improved efficacy from GSM-based products for the purpose of improved animal health.

Governing the quality and safety of healthcare: A conceptual framework.

PubMed

Brown, Alison; Dickinson, Helen; Kelaher, Margaret

2018-04-01

Recent research has advanced understanding of corporate governance of healthcare quality, highlighting the need for future empirical work to develop beyond a focus on board composition to a more detailed exploration of the internal workings of governance that influence board engagement and activities. This paper proposes a conceptual framework to guide empirical research examining the work of board and senior management in governing healthcare quality. To generate this framework, existing conceptual approaches and key constructs influencing effectiveness are identified in the governance literature. Commonalities between governance and team effectiveness literature are mapped and suggest a number of key constructs in the team effectiveness literature are applicable to, but not yet fully explored, within the governance literature. From these we develop a healthcare governance conceptual framework encompassing both literatures, that outlines input and mediating factors influencing governance. The mapping process highlights gaps in research related to board dynamics and external influences that require further investigation. Organizing the multiple complex factors that influence governance of healthcare quality in a conceptual framework brings a new perspective to structuring theory-led research and informing future policy initiatives. Copyright © 2018 Elsevier Ltd. All rights reserved.

Integration and Development in Schizotypy Research: An Introduction to the Special Supplement

PubMed Central

Debbané, Martin; Mohr, Christine

2015-01-01

In its fifth decade of existence, the construct of schizotypy is recapturing the early scientific interest it attracted when Paul E. Meehl (1920–2003), who coined the term, pioneered the field of schizotypy research. The International Lemanic Workshop on Schizotypy, hosted at the University of Geneva in December 2013, recently offered an opportunity to address some of the fundamental questions in contemporary schizotypy research and situate the construct in the greater scheme of future scientific projects on schizophrenia and psychological health research. What kind of knowledge has schizotypy research provided in furthering our understanding of schizophrenia? What types of questions can schizotypy research tackle, and which are the conceptual and methodological frameworks to address them? How will schizotypy research contribute to future scientific endeavors? The International Lemanic Workshop brought together leading experts in the field around the tasks of articulating the essential findings in schizotypy research, as well as providing some key insights and guidance to face scientific challenges of the future. The current supplement contains 8 position articles, 4 research articles, and 1 invited commentary that outline the state of the art in schizotypy research today. PMID:25810053

Cognitive Attachment Model of Voices: Evidence Base and Future Implications

PubMed Central

Berry, Katherine; Varese, Filippo; Bucci, Sandra

2017-01-01

There is a robust association between hearing voices and exposure to traumatic events. Identifying mediating mechanisms for this relationship is key to theories of voice hearing and the development of therapies for distressing voices. This paper outlines the Cognitive Attachment model of Voices (CAV), a theoretical model to understand the relationship between earlier interpersonal trauma and distressing voice hearing. The model builds on attachment theory and well-established cognitive models of voices and argues that attachment and dissociative processes are key psychological mechanisms that explain how trauma influences voice hearing. Following the presentation of the model, the paper will review the current state of evidence regarding the proposed mechanisms of vulnerability to voice hearing and maintenance of voice-related distress. This review will include evidence from studies supporting associations between dissociation and voices, followed by details of our own research supporting the role of dissociation in mediating the relationship between trauma and voices and evidence supporting the role of adult attachment in influencing beliefs and relationships that voice hearers can develop with voices. The paper concludes by outlining the key questions that future research needs to address to fully test the model and the clinical implications that arise from the work. PMID:28713292

Recent Trends in Robotics Research

NASA Astrophysics Data System (ADS)

Ejiri, Masakazu

My views on recent trends in the strategy and practice of Japan's robotics research are briefly introduced. To meet ever-increasing public expectations, robotics researchers and engineers have to be more seriously concerned about robots' intrinsic weaknesses. Examples of these are power-related and reliability issues. Resolving these issues will increase the feasibility of creating successful new industry, and the likelihood of robotics becoming a key technology for providing a safe and stress-free society in the future.

Developing a Research Agenda to Optimize Diagnostic Imaging in the Emergency Department: An Executive Summary of the 2015 Academic Emergency Medicine Consensus Conference.

PubMed

Marin, Jennifer R; Mills, Angela M

2015-12-01

The 2015 Academic Emergency Medicine consensus conference, "Diagnostic Imaging in the Emergency Department: A Research Agenda to Optimize Utilization" was held on May 12, 2015, with the goal of developing a high-priority research agenda on which to base future research. The specific aims of the conference were to (1) understand the current state of evidence regarding emergency department (ED) diagnostic imaging use and identify key opportunities, limitations, and gaps in knowledge; (2) develop a consensus-driven research agenda emphasizing priorities and opportunities for research in ED diagnostic imaging; and (3) explore specific funding mechanisms available to facilitate research in ED diagnostic imaging. Over a 2-year period, the executive committee and other experts in the field convened regularly to identify specific areas in need of future research. Six content areas within emergency diagnostic imaging were identified before the conference and served as the breakout groups on which consensus was achieved: clinical decision rules; use of administrative data; patient-centered outcomes research; training, education, and competency; knowledge translation and barriers to imaging optimization; and comparative effectiveness research in alternatives to traditional computed tomography use. The executive committee invited key stakeholders to assist with the planning and to participate in the consensus conference to generate a multidisciplinary agenda. There were a total of 164 individuals involved in the conference and spanned various specialties, including general emergency medicine, pediatric emergency medicine, radiology, surgery, medical physics, and the decision sciences.

Belowground Ecology of Scarabs Feeding on Grass Roots: Current Knowledge and Future Directions for Management in Australasia

PubMed Central

Frew, Adam; Barnett, Kirk; Nielsen, Uffe N.; Riegler, Markus; Johnson, Scott N.

2016-01-01

Many scarab beetles spend the majority of their lives belowground as larvae, feeding on grass roots. Many of these larvae are significant pests, causing damage to crops and grasslands. Damage by larvae of the greyback cane beetle (Dermolepida albohirtum), for example, can cause financial losses of up to AU$40 million annually to the Australian sugarcane industry. We review the ecology of some scarab larvae in Australasia, focusing on three subfamilies; Dynastinae, Rutelinae, and Melolonthinae, containing key pest species. Although considerable research on the control of some scarab pests has been carried out in Australasia, for some species, the basic biology and ecology remains largely unexplored. We synthesize what is known about these scarab larvae and outline key knowledge gaps to highlight future research directions with a view to improve pest management. We do this by presenting an overview of the scarab larval host plants and feeding behavior; the impacts of abiotic (temperature, moisture, and fertilization) and biotic (pathogens, natural enemies, and microbial symbionts) factors on scarab larvae and conclude with how abiotic and biotic factors can be applied in agriculture for improved pest management, suggesting future research directions. Several host plant microbial symbionts, such as arbuscular mycorrhizal fungi and endophytes, can improve plant tolerance to scarabs and reduce larval performance, which have shown promise for use in pest management. In addition to this, several microbial scarab pathogens have been isolated for commercial use in pest management with particularly promising results. The entomopathogenic fungus Metarhizium anisopliae caused a 50% reduction in cane beetle larvae while natural enemies such as entomopathogenic nematodes have also shown potential as a biocontrol. Key abiotic factors, such as soil water, play an important role in affecting both scarab larvae and these control agents and should therefore feature in future multi-factorial experiments. Continued research should focus on filling knowledge gaps including host plant preferences, attractive trap crops, and naturally occurring pathogens that are locally adapted, to achieve high efficacy in the field. PMID:27047506

Psychological Therapies for Auditory Hallucinations (Voices): Current Status and Key Directions for Future Research

PubMed Central

Thomas, Neil; Hayward, Mark; Peters, Emmanuelle; van der Gaag, Mark; Bentall, Richard P.; Jenner, Jack; Strauss, Clara; Sommer, Iris E.; Johns, Louise C.; Varese, Filippo; García-Montes, José Manuel; Waters, Flavie; Dodgson, Guy; McCarthy-Jones, Simon

2014-01-01

This report from the International Consortium on Hallucinations Research considers the current status and future directions in research on psychological therapies targeting auditory hallucinations (hearing voices). Therapy approaches have evolved from behavioral and coping-focused interventions, through formulation-driven interventions using methods from cognitive therapy, to a number of contemporary developments. Recent developments include the application of acceptance- and mindfulness-based approaches, and consolidation of methods for working with connections between voices and views of self, others, relationships and personal history. In this article, we discuss the development of therapies for voices and review the empirical findings. This review shows that psychological therapies are broadly effective for people with positive symptoms, but that more research is required to understand the specific application of therapies to voices. Six key research directions are identified: (1) moving beyond the focus on overall efficacy to understand specific therapeutic processes targeting voices, (2) better targeting psychological processes associated with voices such as trauma, cognitive mechanisms, and personal recovery, (3) more focused measurement of the intended outcomes of therapy, (4) understanding individual differences among voice hearers, (5) extending beyond a focus on voices and schizophrenia into other populations and sensory modalities, and (6) shaping interventions for service implementation. PMID:24936081

NHLBI state of the science symposium in therapeutic apheresis: Knowledge gaps and research opportunities in the area of hematology-oncology.

PubMed

Karafin, Matthew S; Sachais, Bruce S; Connelly-Smith, Laura; Field, Joshua J; Linenberger, Michael L; Padmanabhan, Anand

2016-02-01

The National Heart Lung and Blood Institute (NHLBI) hosted a two-day state of the science symposium on therapeutic apheresis in Bethesda, MD on November 28th-29th, 2012. The purpose of the symposium was multifaceted, and included the following aims: (a) To discuss this state of research and key scientific questions in apheresis medicine; (b) To identify gaps in knowledge for relevant cardiovascular diseases, hematological and oncological diseases, infectious diseases and sepsis, renal diseases, and neurological diseases where there may be strong therapeutic rationale for the application of apheresis treatments; (c) To explore ways of coordinating therapeutic apheresis with other medical disciplines and treatment modalities; (d) To identify and prioritize the most important research questions to be answered in apheresis medicine; and (e) To offer NHLBI suggestions on how a structured research approach can be applied to the therapeutic apheresis research agenda in future years. The following document summarizes three such key proposals presented at the meeting for evaluating apheresis therapy for the treatment of pain in sickle cell disease, heparin induced thrombocytopenia, and leukostasis from acute myeloid leukemia. The challenges and limitations regarding apheresis therapy for each disease are discussed, and avenues for future investigation for each disease are outlined. © 2015 Wiley Periodicals, Inc.

Children's Interstitial and Diffuse Lung Disease. Progress and Future Horizons.

PubMed

Deterding, Robin R

2015-10-01

Children's interstitial and diffuse lung disease (chILD) is a term that encompasses a large and diverse group of rare pediatric diseases and disorders. Significant progress has been made over the last 2 decades in classification, clinical care, research, and organizational structure to enhance the care of children with these high-morbidity and -mortality diseases. New diseases have been defined clinically and genetically, classification systems developed and applied, organizations formed such as the chILD Research Network (chILDRN) and chILD Foundation, and basic and translational science expanded to focus on chILD diseases. Multidisciplinary collaborations and efforts to advance understanding and treatment of chILD have been extended worldwide. The future horizon holds great promise to expand scientific discoveries, collaborate more broadly, and bring new treatment to these children. An overview of key historical past developments, major clinical and research updates, and opportunities for the future in chILD is reviewed in this Perspective.

Summary: The natural history and immunobiology of Chlamydia trachomatis genital infection and implications for Chlamydia control.

PubMed

Gottlieb, Sami L; Martin, David H; Xu, Fujie; Byrne, Gerald I; Brunham, Robert C

2010-06-15

In 2008, the US Centers for Disease Control and Prevention held the Chlamydia Immunology and Control Expert Advisory Meeting to foster a dialogue among basic scientists, clinical researchers, and epidemiologists studying genital Chlamydia trachomatis infection. The objectives of the meeting were to determine key questions related to C. trachomatis natural history and immunobiology, with implications for control programs;to review existing data on these key questions; and to delineate research needs to address remaining gaps in knowledge. The 9 articles in this supplement to The Journal of Infectious Diseases describe salient findings presented at the 2008 meeting, and this commentary summarizes and synthesizes these articles and discusses implications for chlamydia control efforts and future research priorities.

Securing Wireless Communications of the Internet of Things from the Physical Layer, An Overview

NASA Astrophysics Data System (ADS)

Zhang, Junqing; Duong, Trung; Woods, Roger; Marshall, Alan

2017-08-01

The security of the Internet of Things (IoT) is receiving considerable interest as the low power constraints and complexity features of many IoT devices are limiting the use of conventional cryptographic techniques. This article provides an overview of recent research efforts on alternative approaches for securing IoT wireless communications at the physical layer, specifically the key topics of key generation and physical layer encryption. These schemes can be implemented and are lightweight, and thus offer practical solutions for providing effective IoT wireless security. Future research to make IoT-based physical layer security more robust and pervasive is also covered.

Toward a Fast-Response Active Turbine Tip Clearance Control

NASA Technical Reports Server (NTRS)

Melcher, Kevin J.; Kypuros, Javier A.

2003-01-01

This paper describes active tip clearance control research being conducted by NASA to improve turbine engine systems. The target application for this effort is commercial aircraft engines. However, technologies developed for clearance control can benefit a broad spectrum of current and future turbomachinery. The first portion of the paper addresses the research from a programmatic viewpoint. Recent studies that provide motivation for the work, identification of key technologies, and NASA's plan for addressing deficiencies in the technologies are discussed. The later portion of the paper drills down into one of the key technologies by presenting equations and results for a preliminary dynamic model of the tip clearance phenomena.

Getting to zero the biomedical way in Africa: outcomes of deliberation at the 2013 Biomedical HIV Prevention Forum in Abuja, Nigeria

PubMed Central

2014-01-01

Background Over the last few decades, biomedical HIV prevention research had engaged multiple African stakeholders. There have however been few platforms to enable regional stakeholders to engage with one another. In partnership with the World AIDS Campaign International, the Institute of Public Health of Obafemi Awolowo University, and the National Agency for the Control of AIDS in Nigeria, the New HIV Vaccine and Microbicide Advocacy Society hosted a forum on biomedical HIV prevention research in Africa. Stakeholders’ present explored evidences related to biomedical HIV prevention research and development in Africa, and made recommendations to inform policy, guidelines and future research agenda. Discussion The BHPF hosted 342 participants. Topics discussed included the use of antiretrovirals for HIV prevention, considerations for biomedical HIV prevention among key populations; HIV vaccine development; HIV cure; community and civil society engagement; and ethical considerations in implementation of biomedical HIV prevention research. Participants identified challenges for implementation of proven efficacious interventions and discovery of other new prevention options for Africa. Concerns raised included limited funding by African governments, lack of cohesive advocacy and policy agenda for biomedical HIV prevention research and development by Africa, varied ethical practices, and limited support to communities’ capacity to actively engaged with clinical trial conducts. Participants recommended that the African Government implement the Abuja +12 declaration; the civil society build stronger partnerships with diverse stakeholders, and develop a coherent advocacy agenda that also enhances community research literacy; and researchers and sponsors of trials on the African continent establish a process for determining appropriate standards for trial conduct on the continent. Conclusion By highlighting key considerations for biomedical HIV prevention research and development in Africa, the forum has helped identify key advocacy issues that Civil Society can expend efforts on so as to strengthen support for future biomedical HIV prevention research on the continent. PMID:26636825

Getting to zero the biomedical way in Africa: outcomes of deliberation at the 2013 Biomedical HIV Prevention Forum in Abuja, Nigeria.

PubMed

Folayan, Morenike Oluwatoyin; Gottemoeller, Megan; Mburu, Rosemary; Brown, Brandon

2014-01-01

Over the last few decades, biomedical HIV prevention research had engaged multiple African stakeholders. There have however been few platforms to enable regional stakeholders to engage with one another. In partnership with the World AIDS Campaign International, the Institute of Public Health of Obafemi Awolowo University, and the National Agency for the Control of AIDS in Nigeria, the New HIV Vaccine and Microbicide Advocacy Society hosted a forum on biomedical HIV prevention research in Africa. Stakeholders' present explored evidences related to biomedical HIV prevention research and development in Africa, and made recommendations to inform policy, guidelines and future research agenda. The BHPF hosted 342 participants. Topics discussed included the use of antiretrovirals for HIV prevention, considerations for biomedical HIV prevention among key populations; HIV vaccine development; HIV cure; community and civil society engagement; and ethical considerations in implementation of biomedical HIV prevention research. Participants identified challenges for implementation of proven efficacious interventions and discovery of other new prevention options for Africa. Concerns raised included limited funding by African governments, lack of cohesive advocacy and policy agenda for biomedical HIV prevention research and development by Africa, varied ethical practices, and limited support to communities' capacity to actively engaged with clinical trial conducts. Participants recommended that the African Government implement the Abuja +12 declaration; the civil society build stronger partnerships with diverse stakeholders, and develop a coherent advocacy agenda that also enhances community research literacy; and researchers and sponsors of trials on the African continent establish a process for determining appropriate standards for trial conduct on the continent. By highlighting key considerations for biomedical HIV prevention research and development in Africa, the forum has helped identify key advocacy issues that Civil Society can expend efforts on so as to strengthen support for future biomedical HIV prevention research on the continent.

Future research needs associated with the assessment of potential human health risks from exposure to toxic ambient air pollutants.

PubMed Central

Möller, L; Schuetzle, D; Autrup, H

1994-01-01

This paper presents key conclusions and future research needs from a Workshop on the Risk Assessment of Urban Air, Emissions, Exposure, Risk Identification, and Quantification, which was held in Stockholm during June 1992 by 41 participants from 13 countries. Research is recommended in the areas of identification and quantification of toxics in source emissions and ambient air, atmospheric transport and chemistry, exposure level assessment, the development of improved in vitro bioassays, biomarker development, the development of more accurate epidemiological methodologies, and risk quantification techniques. Studies are described that will be necessary to assess and reduce the level of uncertainties associated with each step of the risk assessment process. International collaborative research efforts between industry and government organizations are recommended as the most effective way to carry out this research. PMID:7529703

Physician Acceptance of Gateway to Care at Irwin Army Community Hospital

DTIC Science & Technology

1992-07-27

frontier cavalry post once commanded by General George Armstrong Custer. Today it is the home of almost 20,000 soldiers of the Big Red One, First Infantry...especially important for the future. Physicians, as key "players" in healthcare organizations, are also key to the success of Gateway to Care. Kotler and...research (3rd ed.). New York: Holt. Physician Acceptance 32 Kotler , P., & Clarke, R. (1987). Marketing for health care organizations. Englewood Cliffs

The Five Key Questions of Human Performance Modeling.

PubMed

Wu, Changxu

2018-01-01

Via building computational (typically mathematical and computer simulation) models, human performance modeling (HPM) quantifies, predicts, and maximizes human performance, human-machine system productivity and safety. This paper describes and summarizes the five key questions of human performance modeling: 1) Why we build models of human performance; 2) What the expectations of a good human performance model are; 3) What the procedures and requirements in building and verifying a human performance model are; 4) How we integrate a human performance model with system design; and 5) What the possible future directions of human performance modeling research are. Recent and classic HPM findings are addressed in the five questions to provide new thinking in HPM's motivations, expectations, procedures, system integration and future directions.

Subsonic Aircraft Safety Icing Study

NASA Technical Reports Server (NTRS)

Jones, Sharon Monica; Reveley, Mary S.; Evans, Joni K.; Barrientos, Francesca A.

2008-01-01

NASA's Integrated Resilient Aircraft Control (IRAC) Project is one of four projects within the agency s Aviation Safety Program (AvSafe) in the Aeronautics Research Mission Directorate (ARMD). The IRAC Project, which was redesigned in the first half of 2007, conducts research to advance the state of the art in aircraft control design tools and techniques. A "Key Decision Point" was established for fiscal year 2007 with the following expected outcomes: document the most currently available statistical/prognostic data associated with icing for subsonic transport, summarize reports by subject matter experts in icing research on current knowledge of icing effects on control parameters and establish future requirements for icing research for subsonic transports including the appropriate alignment. This study contains: (1) statistical analyses of accident and incident data conducted by NASA researchers for this "Key Decision Point", (2) an examination of icing in other recent statistically based studies, (3) a summary of aviation safety priority lists that have been developed by various subject-matter experts, including the significance of aircraft icing research in these lists and (4) suggested future requirements for NASA icing research. The review of several studies by subject-matter experts was summarized into four high-priority icing research areas. Based on the Integrated Resilient Aircraft Control (IRAC) Project goals and objectives, the IRAC project was encouraged to conduct work in all of the high-priority icing research areas that were identified, with the exception of the developing of methods to sense and document actual icing conditions.

Application of the new scenario framework for climate change research: Future social vulnerability in large urban areas

NASA Astrophysics Data System (ADS)

Rohat, Guillaume; Flacke, Johannes; Dao, Hy

2016-04-01

It is by now widely acknowledged that future social vulnerability to climate change depends on both future climate state and future socio-economic conditions. Nevertheless, while most of the vulnerability assessments are using climate projections, the integration of socio-economic projections into the assessment of vulnerabilities has been very limited. Up to now, the vast majority of vulnerability assessments has been using current socio-economic conditions, hence has failed to consider the influence of socio-economic developments in the construction of vulnerability. To enhance the use of socio-economic projections into climate change impacts, adaptation and vulnerability assessments, the climate change research community has been recently involved in the development of a new model for creating scenarios that integrate future changes in climate as well as in society, known under the name of the new scenario framework for climate change research. This theoretical framework is made of a set of alternative futures of socio-economic developments (known as shared socio-economic pathways - SSPs), a set of hypothesis about future climate policies (known as shared policy assumptions - SPAs) and a set of greenhouse gas concentration trajectories (known as representative concentration pathways - RCPs), which are all combined into a scenario matrix architecture (SMA) whose aim is to facilitate the use of this framework. Despite calls by the climate change research community for the use of this conceptual framework in impacts, adaptation and vulnerability research, its use and its assessment has been very limited. Focusing on case-studies (i.e. specific cities as well as specific climate impacts and their associated human exposures and vulnerabilities), the study presented here will attempt to operationalize this theoretical framework for the assessment of future social vulnerability in large urban areas. A particular attention will be paid to less advanced and more vulnerable countries in the global south. We will discuss how this framework can be implemented for large urban agglomerations. To do so, we will examine: (i) by what means globally-developed SSPs can be extended into sector-specific and location-specific socio-economic development scenarios, (ii) in what manner the quantification of key socio-economic indicators (in accordance with the different SSPs), coupled with regional climate projections under different RCPs, can lead to a quantitative and reliable assessment of the evolution of future social vulnerability, and (iii) to which extent the SMA, i.e. the combination of extended SSPs, regional climate projections (under different RCPs) and various locally-developed SPAs, can answer some of the key questions regarding climate change adaptation policies, from a vulnerability perspective.

Recent trends for practical rehabilitation robotics, current challenges and the future.

PubMed

Yakub, Fitri; Md Khudzari, Ahmad Zahran; Mori, Yasuchika

2014-03-01

This paper presents and studies various selected literature primarily from conference proceedings, journals and clinical tests of the robotic, mechatronics, neurology and biomedical engineering of rehabilitation robotic systems. The present paper focuses of three main categories: types of rehabilitation robots, key technologies with current issues and future challenges. Literature on fundamental research with some examples from commercialized robots and new robot development projects related to rehabilitation are introduced. Most of the commercialized robots presented in this paper are well known especially to robotics engineers and scholars in the robotic field, but are less known to humanities scholars. The field of rehabilitation robot research is expanding; in light of this, some of the current issues and future challenges in rehabilitation robot engineering are recalled, examined and clarified with future directions. This paper is concluded with some recommendations with respect to rehabilitation robots.

The Future of Memory: Remembering, Imagining, and the Brain

PubMed Central

Schacter, Daniel L.; Addis, Donna Rose; Hassabis, Demis; Martin, Victoria C.; Spreng, R. Nathan; Szpunar, Karl K.

2013-01-01

During the past few years, there has been a dramatic increase in research examining the role of memory in imagination and future thinking. This work has revealed striking similarities between remembering the past and imagining or simulating the future, including the finding that a common brain network underlies both memory and imagination. Here we discuss a number of key points that have emerged during recent years, focusing in particular on the importance of distinguishing between temporal and non-temporal factors in analyses of memory and imagination, the nature of differences between remembering the past and imagining the future, the identification of component processes that comprise the default network supporting memory-based simulations, and the finding that this network can couple flexibly with other networks to support complex goal-directed simulations. This growing area of research has broadened our conception of memory by highlighting the many ways in which memory supports adaptive functioning. PMID:23177955

Culture, Globalisation and the Study of Giftedness: Reflections on Persson's Analysis and Recommendations for Future Research

ERIC Educational Resources Information Center

Foreman, Jennifer; Renzulli, Joseph

2012-01-01

Dr. Persson's (2012a) target article addresses a number of key points that will greatly impact the study of giftedness, gifted education, and talent development in the "flat" world of the 21st century and beyond. Research in these areas needs to continually reflect upon changes in the social world outside its narrow purview to validate its…

Etiology and sequelae of root resorption.

PubMed

Vlaskalic, V; Boyd, R L; Baumrind, S

1998-06-01

This article reviews the current status of investigation into apical root resorption within the context of orthodontic treatment. Treatment and patient factors that have traditionally been investigated are discussed, along with the results of current research in this area. The need for rethinking traditional research strategies in the quest for identifying both control and causative mechanisms is explored. Finally, proposals for key areas of future interest are highlighted.

School Psychology Research and Practice in East Asia: Perspectives on the Past, Present, and Future Directions of the Field

ERIC Educational Resources Information Center

Brown, Jacqueline A.; Watanabe, Yayoi; Lee, Dong Hun; McIntosh, Kent

2016-01-01

To engage in a comparison of school psychology research and practice in eastern and western countries, the current study sought to identify key themes that have influenced the field of school psychology in East Asian countries. Forty-six leading school psychology professionals in Japan, Hong Kong, South Korea, Thailand, and Taiwan provided their…

Financial Sustainability and Efficiency in Full Economic Costing of Research in UK Higher Education Institutions

ERIC Educational Resources Information Center

Universities UK, 2010

2010-01-01

A Task Group was created to consider the financial sustainability of research undertaken in universities and other institutions of higher education in the United Kingdom. The UK has a very successful Higher Education sector across all key areas of activity, but it is vital that the sector reinvests for the future and is transparent in the use of…

Procuring a Sustainable Future: An Action Learning Approach to the Development and Modelling of Ethical and Sustainable Procurement Practices

ERIC Educational Resources Information Center

Boak, George; Watt, Peter; Gold, Jeff; Devins, David; Garvey, Robert

2016-01-01

This paper contributes to an understanding of the processes by which organisational actors learn how to affect positive and sustainable social change in their local region through action learning, action research and appreciative inquiry. The paper is based on a critically reflective account of key findings from an ongoing action research project,…

Wildlife disease and environmental health in Alaska

USGS Publications Warehouse

Van Hemert, Caroline; Pearce, John; Oakley, Karen; Whalen, Mary

2013-01-01

Environmental health is defined by connections between the physical environment, ecological health, and human health. Current research within the U.S. Geological Survey (USGS) recognizes the importance of this integrated research philosophy, which includes study of disease and pollutants as they pertain to wildlife and humans. Due to its key geographic location and significant wildlife resources, Alaska is a critical area for future study of environmental health.

Holo-analysis.

PubMed

Rosen, G D

2006-06-01

Meta-analysis is a vague descriptor used to encompass very diverse methods of data collection analysis, ranging from simple averages to more complex statistical methods. Holo-analysis is a fully comprehensive statistical analysis of all available data and all available variables in a specified topic, with results expressed in a holistic factual empirical model. The objectives and applications of holo-analysis include software production for prediction of responses with confidence limits, translation of research conditions to praxis (field) circumstances, exposure of key missing variables, discovery of theoretically unpredictable variables and interactions, and planning future research. Holo-analyses are cited as examples of the effects on broiler feed intake and live weight gain of exogenous phytases, which account for 70% of variation in responses in terms of 20 highly significant chronological, dietary, environmental, genetic, managemental, and nutrient variables. Even better future accountancy of variation will be facilitated if and when authors of papers routinely provide key data for currently neglected variables, such as temperatures, complete feed formulations, and mortalities.

Children's nursing research: toward development, drudgery or demise?

PubMed

Long, Tony

This paper, based on a presentation to the UK Association of Chief Children's Nurses, is the author's personal reflection on the nature and future of children's nursing research. Key constitutive elements of this concept are considered to arrive at the conclusion that children's nursing research is research undertaken by children's nurses into questions of relevance to children's nursing practice and services, or wider issues in which children's nursing has a vital role. Three possible futures are presented, of which only the last is positive and desirable: development in line with the reality of practice and population needs. An integrated approach is necessary, with responsibilities both for those in positions of authority in the service and for researchers themselves. In particular, this partnership is essential for children's nursing to evidence the impact of research and for children and young people to reap the greatest benefit from evidence-based practice.

Using Visual Scene Displays as Communication Support Options for People with Chronic, Severe Aphasia: A Summary of AAC Research and Future Research Directions.

PubMed

Beukelman, David R; Hux, Karen; Dietz, Aimee; McKelvey, Miechelle; Weissling, Kristy

2015-01-01

Research about the effectiveness of communicative supports and advances in photographic technology has prompted changes in the way speech-language pathologists design and implement interventions for people with aphasia. The purpose of this paper is to describe the use of photographic images as a basis for developing communication supports for people with chronic aphasia secondary to sudden-onset events due to cerebrovascular accidents (strokes). Topics include the evolution of AAC-based supports as they relate to people with aphasia, the development and key features of visual scene displays (VSDs), and future directions concerning the incorporation of photographs into communication supports for people with chronic and severe aphasia.

The F-18 systems research aircraft facility

NASA Technical Reports Server (NTRS)

Sitz, Joel R.

1992-01-01

To help ensure that new aerospace initiatives rapidly transition to competitive U.S. technologies, NASA Dryden Flight Research Facility has dedicated a systems research aircraft facility. The primary goal is to accelerate the transition of new aerospace technologies to commercial, military, and space vehicles. Key technologies include more-electric aircraft concepts, fly-by-light systems, flush airdata systems, and advanced computer architectures. Future aircraft that will benefit are the high-speed civil transport and the National AeroSpace Plane. This paper describes the systems research aircraft flight research vehicle and outlines near-term programs.

What tourist business managers must learn from disaster research.

PubMed

Drabek, Thomas E

2016-01-01

Death and social disruption caused by disasters of varying forms will continue to increase in the future. So too will the impacts on tourism, now one of the fastest growing and largest sectors of the worldwide economy. Tourist business managers must implement evidence-based preparedness activities to enhance the survival potential and future profitability of their firms. Drawing upon recent research studies of the tourist industry during times of crisis and the broad social science knowledge base regarding human responses to disaster, seven key lessons are described. Emergency managers must facilitate the incorporation of these lessons into the culture of tourist business managers.

Evidence base and future research directions in the management of low back pain

PubMed Central

Abbott, Allan

2016-01-01

Low back pain (LBP) is a prevalent and costly condition. Awareness of valid and reliable patient history taking, physical examination and clinical testing is important for diagnostic accuracy. Stratified care which targets treatment to patient subgroups based on key characteristics is reliant upon accurate diagnostics. Models of stratified care that can potentially improve treatment effects include prognostic risk profiling for persistent LBP, likely response to specific treatment based on clinical prediction models or suspected underlying causal mechanisms. The focus of this editorial is to highlight current research status and future directions for LBP diagnostics and stratified care. PMID:27004162

What New Knowledge Would Help Policymakers Better Balance Investments for Optimal Health Outcomes?

PubMed Central

Kindig, David; Day, Patricia; Fox, Daniel M; Gibson, Mark; Knickman, James; Lomas, Jonathan; Stoddart, Gregory

2003-01-01

Objective Review the limitations in cross-sectoral health outcomes research and suggest a future research agenda. Data Sources, Study Design, Data Collection Literature review and workshop discussion. Principal Findings The research evidence that would aid public and private policy makers in answering the question the title poses is quite limited. Conclusions Much more evidence from diverse disciplines is needed, and key areas are suggested. Criteria for progress by 2010 are proposed. PMID:14727804

Psychological therapies for auditory hallucinations (voices): current status and key directions for future research.

PubMed

Thomas, Neil; Hayward, Mark; Peters, Emmanuelle; van der Gaag, Mark; Bentall, Richard P; Jenner, Jack; Strauss, Clara; Sommer, Iris E; Johns, Louise C; Varese, Filippo; García-Montes, José Manuel; Waters, Flavie; Dodgson, Guy; McCarthy-Jones, Simon

2014-07-01

This report from the International Consortium on Hallucinations Research considers the current status and future directions in research on psychological therapies targeting auditory hallucinations (hearing voices). Therapy approaches have evolved from behavioral and coping-focused interventions, through formulation-driven interventions using methods from cognitive therapy, to a number of contemporary developments. Recent developments include the application of acceptance- and mindfulness-based approaches, and consolidation of methods for working with connections between voices and views of self, others, relationships and personal history. In this article, we discuss the development of therapies for voices and review the empirical findings. This review shows that psychological therapies are broadly effective for people with positive symptoms, but that more research is required to understand the specific application of therapies to voices. Six key research directions are identified: (1) moving beyond the focus on overall efficacy to understand specific therapeutic processes targeting voices, (2) better targeting psychological processes associated with voices such as trauma, cognitive mechanisms, and personal recovery, (3) more focused measurement of the intended outcomes of therapy, (4) understanding individual differences among voice hearers, (5) extending beyond a focus on voices and schizophrenia into other populations and sensory modalities, and (6) shaping interventions for service implementation. © The Author 2014. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center.

The face, the future, and dental practice: how research in craniofacial biology will influence patient care.

PubMed

Townsend, G C; Brook, A H

2014-06-01

It has been a privilege to assemble a group of Australian and international researchers to produce a special issue of the Australian Dental Journal that reflects the cutting edge of research in different aspects of craniofacial biology, and also considers how these advances will influence future education and practice within dentistry. The aim of this special issue is to provide a collection of concept papers and critical reviews on key topics that cover both fundamental and applied research in craniofacial biology and to consider the clinical implications. To do this, four questions have been addressed that lead to the four sections of this issue. These are: How have we come to the present exciting position in craniofacial biology with breakthroughs over the past 50 years? What are current fundamental research topics that are helping us to understand more about craniofacial and general development, possibly leading to future clinical developments? What are the current applied research topics that will influence future clinical practice? Looking forward, what new developments in craniofacial biology may come about that will change the face of dental education and practice? The refereed papers in this special issue are grouped into the four sections that seek to respond to these demanding questions. © 2014 Australian Dental Association.

Holocene key coral species in the Northwest Pacific: indicators of reef formation and reef ecosystem responses to global climate change and anthropogenic stresses in the near future

NASA Astrophysics Data System (ADS)

Hongo, Chuki

2012-03-01

The geological record of key coral species that contribute to reef formation and maintenance of reef ecosystems is important for understanding the ecosystem response to global-scale climate change and anthropogenic stresses in the near future. Future responses can be predicted from accumulated data on Holocene reef species identified in drillcore and from data on raised reef terraces. The present study analyzes a dataset based on 27 drillcores, raised reef terraces, and 134 radiocarbon and U-Th ages from reefs of the Northwest Pacific, with the aim of examining the role of key coral species in reef growth and maintenance for reef ecosystem during Holocene sea-level change. The results indicate a latitudinal change in key coral species: arborescent Acropora (Acropora intermedia and Acropora muricata) was the dominant reef builder at reef crests in the tropics, whereas Porites (Porites australiensis, Porites lutea, and Porites lobata) was the dominant contributor to reef growth in the subtropics between 10,000 and 7000 cal. years BP (when the rate of sea-level rise was 10 m/ka). Acropora digitifera, Acropora hyacinthus, Acropora robusta/A. abrotanoides, Isopora palifera, Favia stelligera, and Goniastrea retiformis from the corymbose and tabular Acropora facies were the main key coral species at reef crests between 7000 and 5000 cal. years BP (when the rate of sea-level rise was 5 m/ka) and during the following period of stable sea-level. Massive Porites (P. australiensis, P. lutea, and P. lobata) contributed to reef growth in shallow lagoons during the period of stable sea level. Key coral species from the corymbose and tabular Acropora facies have the potential to build reefs and maintain ecosystems in the near future under a global sea-level rise of 2-6 m/ka, as do key coral species from the arborescent Acropora facies and massive Porites facies, which show vigorous growth and are tolerant to relatively deep-water, low-energy environments. However, these species are likely to experience severe mortality in upcoming decades due to natural and anthropogenic stresses. Consequently, this damage will lead to a collapse in reef formation and the maintenance of reef ecosystems in the near future. This study emphasizes the need for research into the conservation of key coral species.

Electricity Market Games: How Agent-Based Modeling Can Help under High Penetrations of Variable Generation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gallo, Giulia

Integrating increasingly high levels of variable generation in U.S. electricity markets requires addressing not only power system and grid modeling challenges but also an understanding of how market participants react and adapt to them. Key elements of current and future wholesale power markets can be modeled using an agent-based approach, which may prove to be a useful paradigm for researchers studying and planning for power systems of the future.

Defense Science Board Task Force on The Manufacturing Technology Program: A Key to Affordably Equipping the Future Force

DTIC Science & Technology

2006-02-01

technology for cost and risk reduction of products, software, and processes; long-term, multi-Service needs; and disruptive technologies , both...initiatives and for disruptive technologies , the Office of the Secretary of Defense (OSD) can better promote the importance and value of the program...multi- Service programs, research in “ disruptive ” technologies , and SBIR programs. Balance current, near term, and future needs as well as small and

Making Professional Decisions in Research: Measurement and Key Predictors

PubMed Central

Antes, Alison L.; Chibnall, John T.; Baldwin, Kari A.; Tait, Raymond C.; Vander Wal, Jillon S.; DuBois, James M.

2016-01-01

The professional decision-making in research (PDR) measure was administered to 400 NIH-funded and industry-funded investigators, along with measures of cynicism, moral disengagement, compliance disengagement, impulsivity, work stressors, knowledge of responsible conduct of research (RCR), and socially desirable response tendencies. Negative associations were found for the PDR and measures of cynicism, moral disengagement, and compliance disengagement, while positive associations were found for the PDR and RCR knowledge and positive urgency, an impulsivity subscale. PDR scores were not related to socially desirable responding, or to measures of work stressors and the remaining impulsivity subscales. In a multivariate logistic regression analysis, lower moral disengagement scores, higher RCR knowledge, and identifying the United States as one’s nation of origin emerged as key predictors of stronger performance on the PDR. The implications of these findings for understanding the measurement of decision-making in research and future directions for research and RCR education are discussed. PMID:27093003

Satellite Communications for Aeronautical Applications: Recent research and Development Results

NASA Technical Reports Server (NTRS)

Kerczewski, Robert J.

2001-01-01

Communications systems have always been a critical element in aviation. Until recently, nearly all communications between the ground and aircraft have been based on analog voice technology. But the future of global aviation requires a more sophisticated "information infrastructure" which not only provides more and better communications, but integrates the key information functions (communications, navigation, and surveillance) into a modern, network-based infrastructure. Satellite communications will play an increasing role in providing information infrastructure solutions for aviation. Developing and adapting satellite communications technologies for aviation use is now receiving increased attention as the urgency to develop information infrastructure solutions grows. The NASA Glenn Research Center is actively involved in research and development activities for aeronautical satellite communications, with a key emphasis on air traffic management communications needs. This paper describes the recent results and status of NASA Glenn's research program.

Progress, opportunities, and key fields for groundwater quality research under the impacts of human activities in China with a special focus on western China.

PubMed

Li, Peiyue; Tian, Rui; Xue, Chenyang; Wu, Jianhua

2017-05-01

Groundwater quality research is extremely important for supporting the safety of the water supply and human health in arid and semi-arid areas of China. This review article was constructed to report the latest research progress of groundwater quality in western China where groundwater quality is undergoing fast deterioration because of fast economic development and extensive anthropogenic activities. The opportunities brought by increasing public awareness of groundwater quality protection were also highlighted and discussed. To guide and promote further development of groundwater quality research in China, especially in western China, ten key groundwater quality research fields were proposed. The review shows that the intensification of human activities and the associated impacts on groundwater quality in China, especially in western China, has made groundwater quality research increasingly important, and has caught the attention of local, national, and international agencies and scholars. China has achieved some progress in groundwater quality research in terms of national and regional laws, regulations, and financial supports. The future of groundwater quality research in China, especially in western China, is promising reflected by the opportunities highlighted. The key research fields proposed in this article may also inform groundwater quality protection and management at the national and international level.

THE PACIFIC COAST ESTUARINE INFORMATION SYSTEM: CREATING A BASELINE FOR THE FUTURE

EPA Science Inventory

Coastal researchers and managers have a growing need for ready access to a diversity of
data types, including estuarine-specific lists of native and nonindigenous species and estuarine/landscape characteristics. These data are key components in ecological risk assessments in g...

Transnational Higher Education and Sustainable Development: Current Initiatives and Future Prospects

ERIC Educational Resources Information Center

Koehn, Peter H.

2012-01-01

Tertiary educational institutions increasingly are relied upon for sustainable development initiatives. This policy research note analyzes newly available data regarding seven key dimensions of 295 transnational sustainable development projects involving US universities. Comparative regional analysis of the projects profiled in the APLU/AAU…

2014 Section on Pediatrics Knowledge translation Lecture: Clinicians and researchers on the same path toward facilitating family goals for mobility & participation

PubMed Central

Damiano, Diane L.; Leonard, Rebecca

2015-01-01

BACKGROUND The Knowledge Translation (KT) Lecture at CSM 2014 was a personal perspective from a researcher who had been a therapist and a longtime clinician, now a Ph.D. candidate. OBJECTIVE To better integrate research and clinical care, so KT is a seamless rather than separate process. KEY POINTS KT can be enhanced by improved receptivity to evidence, and increasing use of research designs that encourage and even require clinician involvement, from single-subject designs to large-scale pragmatic trials. Clinical practice databases and hiring therapists to provide intervention in research efforts also serve to integrate research and clinical care. Limitations of applying mean group research results to an individual patient were also discussed and suggest an important unanswered topic for future research. CONCLUSION We all need to assume responsibility for the researcher-clinician partnership, making our jobs more joyful and fulfilling, and hopefully the biggest beneficiaries will be our current and future patients. PMID:25822350

International consultation on long-term global health research priorities, research capacity and research uptake in developing countries.

PubMed

Conalogue, David Mc; Kinn, Sue; Mulligan, Jo-Ann; McNeil, Malcolm

2017-03-21

In recognition of the need for long-term planning for global health research, and to inform future global health research priorities, the United Kingdom Department for International Development (DfID) carried out a public consultation between May and June 2015. The consultation aimed to elicit views on the (1) the long-term future global health research priorities; (2) areas likely to be less important over time; (3) how to improve research uptake in low-income countries; and (4) how to build research capacity in low-income countries. An online consultation was used to survey a wide range of participants on global health research priorities. The qualitative data was analysed using a thematic analysis, with frequency of codes in responses tabulated to approximate relative importance of themes and sub-themes. The public consultation yielded 421 responses. The survey responses confirmed the growing importance of non-communicable disease as a global health research priority, being placed above infectious diseases. Participants felt that the key area for reducing funding prioritisation was infectious diseases. The involvement of policymakers and other key stakeholders was seen as critical to drive research uptake, as was collaboration and partnership. Several methods to build research capacity in low-income countries were described, including capacity building educational programmes, mentorship programmes and research institution collaboration and partnership. The outcomes from this consultation survey provide valuable insights into how DfID stakeholders prioritise research. The outcomes from this survey were reviewed alongside other elements of a wider DfID consultation process to help inform long-term research prioritisation of global health research. There are limitations in this approach; the opportunistic nature of the survey's dissemination means the findings presented may not be representative of the full range of stakeholders or views.

Modeling a space-based quantum link that includes an adaptive optics system

NASA Astrophysics Data System (ADS)

Duchane, Alexander W.; Hodson, Douglas D.; Mailloux, Logan O.

2017-10-01

Quantum Key Distribution uses optical pulses to generate shared random bit strings between two locations. If a high percentage of the optical pulses are comprised of single photons, then the statistical nature of light and information theory can be used to generate secure shared random bit strings which can then be converted to keys for encryption systems. When these keys are incorporated along with symmetric encryption techniques such as a one-time pad, then this method of key generation and encryption is resistant to future advances in quantum computing which will significantly degrade the effectiveness of current asymmetric key sharing techniques. This research first reviews the transition of Quantum Key Distribution free-space experiments from the laboratory environment to field experiments, and finally, ongoing space experiments. Next, a propagation model for an optical pulse from low-earth orbit to ground and the effects of turbulence on the transmitted optical pulse is described. An Adaptive Optics system is modeled to correct for the aberrations caused by the atmosphere. The long-term point spread function of the completed low-earth orbit to ground optical system is explored in the results section. Finally, the impact of this optical system and its point spread function on an overall quantum key distribution system as well as the future work necessary to show this impact is described.

It is getting hotter in here: determining and projecting the impacts of global environmental change on drylands

PubMed Central

Maestre, Fernando T.; Salguero-Gómez, Roberto; Quero, José L.

2012-01-01

Drylands occupy large portions of the Earth, and are a key terrestrial biome from the socio-ecological point of view. In spite of their extent and importance, the impacts of global environmental change on them remain poorly understood. In this introduction, we review some of the main expected impacts of global change in drylands, quantify research efforts on the topic, and highlight how the articles included in this theme issue contribute to fill current gaps in our knowledge. Our literature analyses identify key under-studied areas that need more research (e.g. countries such as Mauritania, Mali, Burkina Faso, Chad and Somalia, and deserts such as the Thar, Kavir and Taklamakan), and indicate that most global change research carried out to date in drylands has been done on a unidisciplinary basis. The contributions included here use a wide array of organisms (from micro-organisms to humans), spatial scales (from local to global) and topics (from plant demography to poverty alleviation) to examine key issues to the socio-ecological impacts of global change in drylands. These papers highlight the complexities and difficulties associated with the prediction of such impacts. They also identify the increased use of long-term experiments and multidisciplinary approaches as priority areas for future dryland research. Major advances in our ability to predict and understand global change impacts on drylands can be achieved by explicitly considering how the responses of individuals, populations and communities will in turn affect ecosystem services. Future research should explore linkages between these responses and their effects on water and climate, as well as the provisioning of services for human development and well-being. PMID:23045705

It is getting hotter in here: determining and projecting the impacts of global environmental change on drylands.

PubMed

Maestre, Fernando T; Salguero-Gómez, Roberto; Quero, José L

2012-11-19

Drylands occupy large portions of the Earth, and are a key terrestrial biome from the socio-ecological point of view. In spite of their extent and importance, the impacts of global environmental change on them remain poorly understood. In this introduction, we review some of the main expected impacts of global change in drylands, quantify research efforts on the topic, and highlight how the articles included in this theme issue contribute to fill current gaps in our knowledge. Our literature analyses identify key under-studied areas that need more research (e.g. countries such as Mauritania, Mali, Burkina Faso, Chad and Somalia, and deserts such as the Thar, Kavir and Taklamakan), and indicate that most global change research carried out to date in drylands has been done on a unidisciplinary basis. The contributions included here use a wide array of organisms (from micro-organisms to humans), spatial scales (from local to global) and topics (from plant demography to poverty alleviation) to examine key issues to the socio-ecological impacts of global change in drylands. These papers highlight the complexities and difficulties associated with the prediction of such impacts. They also identify the increased use of long-term experiments and multidisciplinary approaches as priority areas for future dryland research. Major advances in our ability to predict and understand global change impacts on drylands can be achieved by explicitly considering how the responses of individuals, populations and communities will in turn affect ecosystem services. Future research should explore linkages between these responses and their effects on water and climate, as well as the provisioning of services for human development and well-being.

Arctic Freshwater Synthesis: Summary of key emerging issues

NASA Astrophysics Data System (ADS)

Prowse, T.; Bring, A.; Mârd, J.; Carmack, E.; Holland, M.; Instanes, A.; Vihma, T.; Wrona, F. J.

2015-10-01

In response to a joint request from the World Climate Research Program's Climate and Cryosphere Project, the International Arctic Science Committee, and the Arctic Council's Arctic Monitoring and Assessment Program an updated scientific assessment has been conducted of the Arctic Freshwater System (AFS), entitled the Arctic Freshwater Synthesis (AFSΣ). The major reason behind the joint request was an increasing concern that changes to the AFS have produced, and could produce even greater, changes to biogeophysical and socioeconomic systems of special importance to northern residents and also produce extra-Arctic climatic effects that will have global consequences. The AFSΣ was structured around six key thematic areas: atmosphere, oceans, terrestrial hydrology, terrestrial ecology, resources, and modeling, the review of each coauthored by an international group of scientists and published as separate manuscripts in this special issue of Journal of Geophysical Research-Biogeosciences. This AFSΣ summary manuscript reviews key issues that emerged during the conduct of the synthesis, especially those that are cross-thematic in nature, and identifies future research required to address such issues.

Satellite remote sensing, biodiversity research and conservation of the future

PubMed Central

Pettorelli, Nathalie; Safi, Kamran; Turner, Woody

2014-01-01

Assessing and predicting ecosystem responses to global environmental change and its impacts on human well-being are high priority targets for the scientific community. The potential for synergies between remote sensing science and ecology, especially satellite remote sensing and conservation biology, has been highlighted by many in the past. Yet, the two research communities have only recently begun to coordinate their agendas. Such synchronization is the key to improving the potential for satellite data effectively to support future environmental management decision-making processes. With this themed issue, we aim to illustrate how integrating remote sensing into ecological research promotes a better understanding of the mechanisms shaping current changes in biodiversity patterns and improves conservation efforts. Added benefits include fostering innovation, generating new research directions in both disciplines and the development of new satellite remote sensing products. PMID:24733945

The future of poultry science research: things I think I think.

PubMed

Taylor, R L

2009-06-01

Much poultry research progress has occurred over the first century of the Poultry Science Association. During that time, specific problems have been solved and much basic biological knowledge has been gained. Scientific discovery has exceeded its integration into foundation concepts. Researchers need to be involved in the public's development of critical thinking skills to enable discernment of fact versus fiction. Academic, government, and private institutions need to hire the best people. Issues of insufficient research funding will be remedied by a combination of strategies rather than by a single cure. Scientific advocacy for poultry-related issues is critical to success. Two other keys to the future are funding for higher-risk projects, whose outcome is truly unknown, and specific allocations for new investigators. Diligent, ongoing efforts by poultry scientists will enable progress beyond the challenges.

Enhancing international collaboration among early career researchers.

PubMed

Carroll, Jennifer K; Albada, Akke; Farahani, Mansoureh; Lithner, Maria; Neumann, Melanie; Sandhu, Harbinder; Shepherd, Heather L

2010-09-01

The European Association of Communication in Healthcare (EACH) Early Career Researchers Network (ECRN) aims are to (1) promote international collaboration among young investigators and (2) provide a support network for future innovative communication research projects. In October 2009, Miami, USA at a workshop facilitated by the ECRN at the International Conference on Communication in Healthcare (ICCH) hosted by the American Academy of Communication in Healthcare we explored common facilitators and challenges faced by early career researchers in health communication research. Attendees introduced themselves, their research area(s) of interest, and listed one facilitator and one barrier for their career development. EACH ECRN members then led a discussion of facilitators and challenges encountered in communication research projects and career development. We discussed potential collaboration opportunities, future goals, and activities. Having supportive collegial relationships, institutional support, job security, and funding are critical facilitators for early career investigators. Key challenges include difficulty with time management and prioritizing, limited resources, and contacts. International collaboration among early career researchers is a feasible and effective means to address important challenges, by increasing opportunities for professional support and networking, problem-solving, discussion of data, and ultimately publishing. Future AACH-EACH Early Career Researcher Networks should continue to build collaborations by developing shared research projects, papers, and other scholarly products. Copyright (c) 2010. Published by Elsevier Ireland Ltd.

Enhancing international collaboration among early-career researchers

PubMed Central

Carroll, Jennifer K; Albada, Akke; Farahani, Mansoureh; Lithner, Maria; Neumann, Melanie; Sandhu, Harbinder; Shepherd, Heather L

2010-01-01

Objective The European Association of Communication in Healthcare (EACH) Early Career Researchers Network (ECRN) aims are to (1) promote international collaboration among young investigators and (2) provide a support network for future innovative communication research projects. In October 2009, Miami, USA at a workshop facilitated by the ECRN at the International Conference on Communication in Healthcare (ICCH) hosted by the American Academy of Communication in Healthcare we explored common facilitators and challenges faced by early career researchers in health communication research. Methods Attendees introduced themselves, their research area(s) of interest, and listed one facilitator and one barrier for their career development. EACH ECRN members then led a discussion of facilitators and challenges encountered in communication research projects and career development. We discussed potential collaboration opportunities, future goals, and activities. Results Having supportive collegial relationships, institutional support, job security, and funding are critical facilitators for early career investigators. Key challenges include difficulty with time management and prioritizing, limited resources, and contacts. Conclusion International collaboration among early career researchers is a feasible and effective means to address important challenges, by increasing opportunities for professional support and networking, problem-solving, discussion of data, and ultimately publishing. Practice Implications Future AACH-EACH Early Career Researcher Networks should continue to build collaborations by developing shared research projects, papers, and other scholarly products. PMID:20663630

A comparison of trends in research into home care services in Japan and Korea

PubMed Central

2013-01-01

Background The purpose of this study is to compare of the research trends for home care services in Japan and the Republic of Korea (Korea). In particular, it was compared as the research design, the method of data collection, and key words by literature review. Methods Original articles on home care services were selected from Japanese and Korean journals published from the year of 2004 to 2008. The articles were classified, and compared in terms of the number of articles per year. Results The research design was quite different. Quantitative research design was dominantly conducted in Korea, qualitative research design was used same level of design in Japan. In particular, outcome study was shown in Korean. Conclusions It is suggested that future collaboration be undertaken to improve the variety of research design and method especially in both countries under the aged society. In addition, it provides information concerning research concepts, which can be applied to optimize future home care services. PMID:23870373

Affirming our commitment to research: the Medical Library Association's research policy statement: the process and findings.

PubMed

Grefsheim, Suzanne F; Rankin, Jocelyn A; Perry, Gerald J; McKibbon, K Ann

2008-04-01

Building on its 1995 research policy statement, the Medical Library Association (MLA) has issued a new research policy, The Research Imperative. This paper shares the background research that informed the new policy. Semi-structured interviews were conducted with fifty-one key informants representing various library types, functions, geographic locations, ages, and ethnicities. The grounded theory approach was used to analyze the resulting textual database. Additionally, to gather input from the membership as a whole, two open forums were held at MLA annual meetings. Key informant data indicated that the policy should provide roles for MLA in leadership, advocacy, collaboration, services, education, publishing, and development of a research agenda. Evidence-based library and information practice was emphasized. Six themes emerged to center the new policy: creation of a research culture, challenges, domains of research, research skills set, roles of stakeholders, and measurement of progress. Reflecting the interests and beliefs of the membership, The Research Imperative challenges MLA members to build a supportive culture that values and contributes to a research base that is recognized as an essential tool for future practice.

Outcomes in mothers with rheumatic diseases and their offspring workshop

PubMed Central

Neville, Autumn; Bernatsky, Sasha; Kuriya, Bindee; Bujold, Emmanuel; Chakravarty, Eliza; Platt, Robert W; Bérard, Anick; Vinet, Évelyne

2017-01-01

This conference report describes six presentations that were given during a Canadian Institutes for Health Research-funded workshop. The goal of the workshop was to discuss key knowledge gaps in the study of outcomes in mothers with rheumatic diseases and their offspring. Presentations focused on epidemiological and methodological issues associated with the reproductive and perinatal health of women with rheumatic diseases. Discussions of relevant recent research allowed for discovery of potential data sources that could facilitate interdisciplinary research and created the opportunity for future collaborations.

Research needs to better understand Lake Ontario ecosystem function: A workshop summary

USGS Publications Warehouse

Stewart, Thomas J.; Rudstam, Lars G.; Watkins, James M.; Johnson, Timothy B.; Weidel, Brian C.; Koops, Marten A.

2016-01-01

Lake Ontario investigators discussed and interpreted published and unpublished information during two workshops to assess our current understanding of Lake Ontario ecosystem function and to identify research needs to guide future research and monitoring activities. The purpose of this commentary is to summarize key investigative themes and hypotheses that emerged from the workshops. The outcomes of the workshop discussions are organized under four themes: spatial linkages and interactions, drivers of primary production, trophic transfer, and human interactions.

Research colloquium on occupational respiratory diseases: a conference in Cuba (1984)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rosenstock, L.; Orris, P.

At an international conference in Havana, Cuba, March 19-21, 1984, health professional from the US, Canada, and Cuba participated in a research colloquium on occupational lung diseases. Participants and speakers discussed the state of the art of knowledge, research, and management of key occupational lung diseases, and suggested directions for future efforts. Differences among the three countries in terms of the medical, economic, and social aspects of defining, treating, and compensating occupational diseases were also considered.

1995 Laboratory-Directed Research and Development Annual report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cauffman, D.P.; Shoaf, D.L.; Hill, D.A.

1995-12-31

The Laboratory-Directed Research and Development Program (LDRD) is a key component of the discretionary research conducted by Lockheed Idaho Technologies Company (Lockheed Idaho) at the Idaho National Engineering Laboratory (INEL). The threefold purpose and goal of the LDRD program is to maintain the scientific and technical vitality of the INEL, respond to and support new technical opportunities, and enhance the agility and flexibility of the national laboratory and Lockheed Idaho to address the current and future missions of the Department of Energy.

"We're Changing Our Ways": Women's Coping Strategies for Obesity Risk-reducing Behaviors in American Indian Households.

PubMed

Gadhoke, Preety; Christiansen, Karina; Pardilla, Marla; Frick, Kevin; Gittelsohn, Joel

2015-01-01

This article reveals women caregivers' perceptions and coping strategies to improve households' food and physical activity habits. Results emerged from the pre-intervention formative research phase of a multi-site, multi-level obesity prevention pilot intervention on American Indian (AI) reservations. Using purposive sampling, 250 adults and children participated in qualitative research. Results reveal that having local institutional support was a key structural facilitator. 'Family connectedness' emerged as a key relational facilitator. Hegemony of systems, food deserts, transportation, and weather were key structural barriers; Childcare needs and time constraints were key relational barriers. Women's coping strategies included planning ahead, maximizing, apportioning, tempting healthy, and social support. Findings informed the development and implementation of a novel obesity prevention pilot intervention tailored for each participating AI community addressing culturally relevant messages, institutional policies, and programs. We conclude with future consideration for comparative, ethnicity-based, class-based, and gender-specific studies on women's coping strategies for household health behaviors.

Constructive Parenting.

ERIC Educational Resources Information Center

Goldberg, Sally

This book turns important research and theory into essential, easy-to-follow guidelines for new parents and child care providers to help them focus on the critical first 3 years of life to build a strong foundation for the future. All the key areas of child development are covered, including self-esteem, and cognitive, motor and social…

Emergence of the global research alliance on agricultural greenhouse gases

USDA-ARS?s Scientific Manuscript database

Increasing human population pressure on the Earth is of great concern and a key reason why agricultural and natural resource sciences must be fully engaged to develop solutions for a sustainable future. Increasing population puts pressure on the demand for food, clean water, healthy soil, and a sta...

Preservice Mathematics Teachers' Conceptions of and Approaches to Learning: A Phenomenographic Study

ERIC Educational Resources Information Center

Erdogan, Ahmet

2012-01-01

Knowing the preservice mathematics teachers' conceptions of learning is one of the key factors of taking significant educational measures regarding the future. The purpose of this study was to investigate preservice mathematics teachers' conceptions of and approaches to learning. The phenomenographic qualitative research method was used to…

Embracing the Future: Embedding Digital Repositories in Higher Education Institutions. Research Brief

ERIC Educational Resources Information Center

Hoorens, Stijn; van Dijk, Lidia Villalba; van Stolk, Christian

2009-01-01

This briefing paper captures the key findings and recommendations of a study commissioned by the Joint Information Systems Committee on aspects of the strategic commitment of institutions to repository sustainability. This project, labelled EMBRACE (EMBedding Repositories And Consortial Enhancement), is aimed at enhancing the functionality,…

2016 Annual Report - Argonne Leadership Computing Facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Collins, Jim; Papka, Michael E.; Cerny, Beth A.

The Argonne Leadership Computing Facility (ALCF) helps researchers solve some of the world’s largest and most complex problems, while also advancing the nation’s efforts to develop future exascale computing systems. This report presents some of the ALCF’s notable achievements in key strategic areas over the past year.

Creativity in the Workplace: People, Problems, and Structures.

ERIC Educational Resources Information Center

Mumford, Michael D.; Simonton, Dean Keith

1997-01-01

This introductory article argues that creativity and innovation are key requirements for the growth and adaptation of organizations. Articles focusing on how creativity and innovation can be encouraged in the workplace are reviewed. Useful directions for future research are discussed along with the methodological issues likely to arise. (Author/CR)

Characteristics of Future Ready Leadership: A Research Synthesis

ERIC Educational Resources Information Center

Office of Educational Technology, US Department of Education, 2017

2017-01-01

Strong leadership is essential to systemic, sustainable change in education. Superintendents and their leadership teams, with the support of state and local leaders, are key to leading the transition to digital learning in their districts. Superintendents throughout the country have expressed the desire for evidence-based approaches they can rely…

Finding Environmental Knowledge in SCUBA-Based Textual Materials

ERIC Educational Resources Information Center

Gündogdu, Cemal; Aygün, Yalin; Ilkim, Mehmet

2018-01-01

As marine environments within the adventure domain are future key-settings for recreational SCUBA diving experience, SCUBA-based textual materials should provide insight into environmental knowledge that is well connected to the novice divers' behaviour and attitude. This research is concerned with a major recreational SCUBA diver manual for…

Lavandula angustifolia Miller: English lavender.

PubMed

Denner, Sallie Stoltz

2009-01-01

Folk and traditional therapeutic use of the essential oil of English lavender for pain, infection, relaxation, and sedation dates back centuries. Current research focusing on the inherent synergism of Lavandula angustifolia Miller demonstrates great potential for future applications. Today's investigations may provide the key to eradicating degenerative inflammatory disease, infectious disease, and carcinogenesis.

The New Literacies of Online Reading Comprehension: Future Directions

ERIC Educational Resources Information Center

Coiro, Julie

2012-01-01

Research in four areas has the potential to dramatically improve how practitioners address the challenges of integrating digital texts and tasks into their literacy curriculum. Advances in defining and measuring key components of online reading comprehension are rapidly emerging. In addition, instructional models, such as Internet reciprocal…

Technology and Adolescents: Perspectives on the Things to Come

ERIC Educational Resources Information Center

Katz, Raul L.; Felix, Max; Gubernick, Madlen

2014-01-01

Assuming that, given the processes of technology diffusion, adolescent behavior forecasts future consumption of digital information, it would seem pertinent to study the characteristics of teenager technology use. This research asks: What are the key patterns regarding the use of technology platforms by teenagers? Is technology usage among…

Gene therapy: charting a future course--summary of a National Institutes of Health Workshop, April 12, 2013.

PubMed

O'Reilly, Marina; Federoff, Howard J; Fong, Yuman; Kohn, Donald B; Patterson, Amy P; Ahmed, Nabil; Asokan, Aravind; Boye, Shannon E; Crystal, Ronald G; De Oliveira, Satiro; Gargiulo, Linda; Harper, Scott Q; Ikeda, Yasuhiro; Jambou, Robert; Montgomery, Maureen; Prograis, Lawrence; Rosenthal, Eugene; Sterman, Daniel H; Vandenberghe, Luk H; Zoloth, Laurie; Abedi, Mehrdad; Adair, Jennifer; Adusumilli, Prasad S; Goins, William F; Gray, Jhanelle; Monahan, Paul; Popplewell, Leslie; Sena-Esteves, Miguel; Tannous, Bakhos; Weber, Thomas; Wierda, William; Gopal-Srivastava, Rashmi; McDonald, Cheryl L; Rosenblum, Daniel; Corrigan-Curay, Jacqueline

2014-06-01

Recently, the gene therapy field has begun to experience clinical successes in a number of different diseases using various approaches and vectors. The workshop Gene Therapy: Charting a Future Course, sponsored by the National Institutes of Health (NIH) Office of Biotechnology Activities, brought together early and mid-career researchers to discuss the key scientific challenges and opportunities, ethical and communication issues, and NIH and foundation resources available to facilitate further clinical advances.

Gene Therapy: Charting a Future Course—Summary of a National Institutes of Health Workshop, April 12, 2013

PubMed Central

O'Reilly, Marina; Federoff, Howard J.; Fong, Yuman; Kohn, Donald B.; Patterson, Amy P.; Ahmed, Nabil; Asokan, Aravind; Boye, Shannon E.; Crystal, Ronald G.; De Oliveira, Satiro; Gargiulo, Linda; Harper, Scott Q.; Ikeda, Yasuhiro; Jambou, Robert; Montgomery, Maureen; Prograis, Lawrence; Rosenthal, Eugene; Sterman, Daniel H.; Vandenberghe, Luk H.; Zoloth, Laurie; Abedi, Mehrdad; Adair, Jennifer; Adusumilli, Prasad S.; Goins, William F.; Gray, Jhanelle; Monahan, Paul; Popplewell, Leslie; Sena-Esteves, Miguel; Tannous, Bakhos; Weber, Thomas; Wierda, William; Gopal-Srivastava, Rashmi; McDonald, Cheryl L.; Rosenblum, Daniel

2014-01-01

Abstract Recently, the gene therapy field has begun to experience clinical successes in a number of different diseases using various approaches and vectors. The workshop Gene Therapy: Charting a Future Course, sponsored by the National Institutes of Health (NIH) Office of Biotechnology Activities, brought together early and mid-career researchers to discuss the key scientific challenges and opportunities, ethical and communication issues, and NIH and foundation resources available to facilitate further clinical advances. PMID:24773122

Sensor Webs to Constellations

NASA Astrophysics Data System (ADS)

Cole, M.

2017-12-01

Advanced technology plays a key role in enabling future Earth-observing missions needed for global monitoring and climate research. Rapid progress over the past decade and anticipated for the coming decades have diminished the size of some satellites while increasing the amount of data and required pace of integration and analysis. Sensor web developments provide correlations to constellations of smallsats. Reviewing current advances in sensor webs and requirements for constellations will improve planning, operations, and data management for future architectures of multiple satellites with a common mission goal.

Space Technology 5 - A Successful Micro-Satellite Constellation Mission

NASA Technical Reports Server (NTRS)

Carlisle, Candace; Webb, Evan H.

2007-01-01

The Space Technology 5 (ST5) constellation of three micro-satellites was launched March 22, 2006. During the three-month flight demonstration phase, the ST5 team validated key technologies that will make future low-cost micro-sat constellations possible, demonstrated operability concepts for future micro-sat science constellation missions, and demonstrated the utility of a micro-satellite constellation to perform research-quality science. The ST5 mission was successfully completed in June 2006, demonstrating high-quality science and technology validation results.

Unnatural selection: talent identification and development in sport.

PubMed

Abbott, Angela; Button, Chris; Pepping, Gert-Jan; Collins, Dave

2005-01-01

The early identification of talented individuals has become increasingly important across many performance domains. Current talent identification (TI) schemes in sport typically select on the basis of discrete, unidimensional measures at unstable periods in the athlete's development. In this article, the concept of talent is revised as a complex, dynamical system in which future behaviors emerge from an interaction of key performance determinants such as psychological behaviors, motor abilities, and physical characteristics. Key nonlinear dynamics concepts are related to TI approaches such as sensitivity to initial conditions, transitions, and exponential behavioral distributions. It is concluded that many TI models place an overemphasis on early identification rather than the development of potentially talented performers. A generic model of talent identification and development is proposed that addresses these issues and provides direction for future research.

Management of Nasopharyngeal Carcinoma: Current Practice and Future Perspective.

PubMed

Lee, Anne W M; Ma, Brigette B Y; Ng, Wai Tong; Chan, Anthony T C

2015-10-10

Nasopharyngeal carcinoma of the undifferentiated subtype is endemic to southern China, and patient prognosis has improved significantly over the past three decades because of advances in disease management, diagnostic imaging, radiotherapy technology, and broader application of systemic therapy. Despite the excellent local control with modern radiotherapy, distant failure remains a key challenge. Advances in molecular technology have helped to decipher the molecular pathogenesis of nasopharyngeal carcinoma as well as its etiologic association with the Epstein-Barr virus. This in turn has led to the discovery of novel biomarkers and drug targets, rendering this cancer site a current focus for new drug development. This article reviews and appraises the key literature on the current management of nasopharyngeal carcinoma and future directions in clinical research. © 2015 by American Society of Clinical Oncology.

Preparing for the future: challenges and opportunities for management and leadership skills.

PubMed

Morison, S; McMullan, C

2013-01-01

The aim of the study was to explore dental leaders' perceptions of the current position of leadership in the dental profession. A qualitative, key informant, exploratory research study was used with semi-structured interviews as the means of data collection. Participants were invited based on their role in dental services in the UK and their ability to act as a key informant. Thirteen participants were secured and interviewed either at their workplace or in a University setting. Each interview lasted between 45 and 60 minutes. The findings show that while recognising that a lack of focus on leadership skills has caused problems in the past, current dental leaders are prepared to lead the profession forward. The participants viewed education at all levels as vital to this process and education for leadership at undergraduate level was perceived as an important way forward. The development of effective leaders is essential for all healthcare professions and increasingly is becoming a key focus for the UK dental profession. There is comparatively little research about dental leadership in a UK context and this paper should begin to help to redress the balance and to highlight areas for future consideration. Three broad emergent themes are described and discussed - characteristics and behaviours of dental leaders; challenges for dental leaders; education and training for dental leadership.

INFORMAS (International Network for Food and Obesity/non-communicable diseases Research, Monitoring and Action Support): summary and future directions.

PubMed

Kumanyika, S

2013-10-01

This supplement presents the foundational elements for INFORMAS (International Network for Food and Obesity/non-communicable diseases Research, Monitoring and Action Support). As explained in the overview article by Swinburn and colleagues, INFORMAS has a compelling rationale and has set forth clear objectives, outcomes, principles and frameworks for monitoring and benchmarking key aspects of food environments and the policies and actions that influence the healthiness of food environments. This summary highlights the proposed monitoring approaches for the 10 interrelated INFORMAS modules: public and private sector policies and actions; key aspects of food environments (food composition, labelling, promotion, provision, retail, prices, and trade and investment) and population outcomes (diet quality). This ambitious effort should be feasible when approached in a step-wise manner, taking into account existing monitoring efforts, data sources, country contexts and capacity, and when adequately resourced. After protocol development and pilot testing of the modules, INFORMAS aims to be a sustainable, low-cost monitoring framework. Future directions relate to institutionalization, implementation and, ultimately, to leveraging INFORMAS data in ways that will bring key drivers of food environments into alignment with public health goals. © 2013 The Authors. Obesity Reviews published by John Wiley & Sons Ltd on behalf of the International Association for the Study of Obesity.

Medical research at the Albert Schweitzer Hospital.

PubMed

Issifou, Saadou; Adegnika, Ayola A; Lell, Bertrand

2010-03-01

Built in 1981, the Medical Research Unit is located at the campus of the Albert Schweitzer Hospital. The main scientific activities of this research unit lie on clinical research focusing on antimalarial drugs and vaccines, and basic studies on pathogenesis of infectious diseases. Since 2002 the Medical Research Unit has experience in organising and hosting high quality training in clinical research in collaboration with the Vienna School of Clinical Research and other partners. For the future, this unit is involved as a key partner in the Central African Network on Tuberculosis, HIV/AIDS and Malaria (CANTAM) consortium playing a central role for the excellence in clinical research in Central Africa.

Is the Scoutreach Initiative of Boy Scouts of America Linked to Character Development among Socioeconomically, Racially, and Ethnically Diverse Youth?: Initial Explorations.

PubMed

Wang, Jun; Champine, Robey B; Ferris, Kaitlyn A; Hershberg, Rachel M; Warren, Daniel J; Burkhard, Brian M; Su, Shaobing; Lerner, Richard M

2017-10-01

Youth development programs represent key tools in the work of youth-serving practitioners and researchers who strive to promote character development and other attributes of youth thriving, particularly among youth who may confront structural and social challenges related to their racial, ethnic, and/or economic backgrounds. This article conducts secondary analyses of two previously reported studies of a relatively recent innovation in Boy Scouts of America (BSA) developed for youth from low-income communities, Scoutreach. Our goal is to provide descriptive and admittedly preliminary exploratory information about whether these data sets-one involving a sample of 266 youth of color from socioeconomically impoverished communities in Philadelphia (M age  = 10.54 years, SD = 1.58 years) and the other involving a pilot investigation of 32 youth of color from similar socioeconomic backgrounds in Boston (M age  = 9.97 years, SD = 2.46 years)-provide evidence for a link between program participation and a key indicator of positive development; that is, character development. Across the two data sets, quantitative and qualitative evidence suggested the presence of character development among Scoutreach participants. Limitations of both studies are discussed and implications for future longitudinal research are presented. We suggest that future longitudinal research should test the hypothesis that emotional engagement is key to creating the conditions wherein Scoutreach participation is linked to character development.

Extreme Events and Disaster Risk Reduction - a Future Earth KAN initiative

NASA Astrophysics Data System (ADS)

Frank, Dorothea; Reichstein, Markus

2017-04-01

The topic of Extreme Events in the context of global environmental change is both a scientifically challenging and exciting topic, and of very high societal relevance. The Future Earth Cluster initiative E3S organized in 2016 a cross-community/co-design workshop on Extreme Events and Environments from Climate to Society (http://www.e3s-future-earth.eu/index.php/ConferencesEvents/ConferencesAmpEvents). Based on the results, co-design research strategies and established network of the workshop, and previous activities, E3S is thriving to establish the basis for a longer-term research effort under the umbrella of Future Earth. These led to an initiative for a Future Earth Knowledge Action Network on Extreme Events and Disaster Risk Reduction. Example initial key question in this context include: What are meaningful indices to describe and quantify impact-relevant (e.g. climate) extremes? Which system properties yield resistance and resilience to extreme conditions? What are the key interactions between global urbanization processes, extreme events, and social and infrastructure vulnerability and resilience? The long-term goal of this KAN is to contribute to enhancing the resistance, resilience, and adaptive capacity of socio-ecological systems across spatial, temporal and institutional scales, in particular in the light of hazards affected by ongoing environmental change (e.g. climate change, global urbanization and land use/land cover change). This can be achieved by enhanced understanding, prediction, improved and open data and knowledge bases for detection and early warning decision making, and by new insights on natural and societal conditions and governance for resilience and adaptive capacity.

Preferences and beliefs in ingroup favoritism.

PubMed

Everett, Jim A C; Faber, Nadira S; Crockett, Molly

2015-01-01

Ingroup favoritism-the tendency to favor members of one's own group over those in other groups-is well documented, but the mechanisms driving this behavior are not well understood. In particular, it is unclear to what extent ingroup favoritism is driven by preferences concerning the welfare of ingroup over outgroup members, vs. beliefs about the behavior of ingroup and outgroup members. In this review we analyze research on ingroup favoritism in economic games, identifying key gaps in the literature and providing suggestions on how future work can incorporate these insights to shed further light on when, why, and how ingroup favoritism occurs. In doing so, we demonstrate how social psychological theory and research can be integrated with findings from behavioral economics, providing new theoretical and methodological directions for future research.

Preferences and beliefs in ingroup favoritism

PubMed Central

Everett, Jim A. C.; Faber, Nadira S.; Crockett, Molly

2015-01-01

Ingroup favoritism—the tendency to favor members of one’s own group over those in other groups—is well documented, but the mechanisms driving this behavior are not well understood. In particular, it is unclear to what extent ingroup favoritism is driven by preferences concerning the welfare of ingroup over outgroup members, vs. beliefs about the behavior of ingroup and outgroup members. In this review we analyze research on ingroup favoritism in economic games, identifying key gaps in the literature and providing suggestions on how future work can incorporate these insights to shed further light on when, why, and how ingroup favoritism occurs. In doing so, we demonstrate how social psychological theory and research can be integrated with findings from behavioral economics, providing new theoretical and methodological directions for future research. PMID:25762906

Enhancing diversity in the public health research workforce: the research and mentorship program for future HIV vaccine scientists.

PubMed

Sopher, Carrie J; Adamson, Blythe Jane S; Andrasik, Michele P; Flood, Danna M; Wakefield, Steven F; Stoff, David M; Cook, Ryan S; Kublin, James G; Fuchs, Jonathan D

2015-04-01

We developed and evaluated a novel National Institutes of Health-sponsored Research and Mentorship Program for African American and Hispanic medical students embedded within the international, multisite HIV Vaccine Trials Network, and explored its impact on scientific knowledge, acquired skills, and future career plans. Scholars conducted social, behavioral, clinical, or laboratory-based research projects with HIV Vaccine Trials Network investigators over 8 to 16 weeks (track 1) or 9 to 12 months (track 2). We conducted an in-depth, mixed-methods evaluation of the first 2 cohorts (2011-2013) to identify program strengths, areas for improvement, and influence on professional development. A pre-post program assessment demonstrated increases in self-reported knowledge, professional skills, and interest in future HIV vaccine research. During in-depth interviews, scholars reported that a supportive, centrally administered program; available funding; and highly involved mentors and staff were keys to the program's early success. A multicomponent, mentored research experience that engages medical students from underrepresented communities and is organized within a clinical trials network may expand the pool of diverse public health scientists. Efforts to sustain scholar interest over time and track career trajectories are warranted.

Key future research questions on mediators and moderators of behaviour change processes for substance abuse.

PubMed

Rehm, Jürgen

2008-06-01

In summarizing the key themes and results of the second meeting of the German Addiction Research Network 'Understanding Addiction: Mediators and Moderators of Behaviour Change Process', the following concrete steps forward were laid out to improve knowledge. The steps included pleas to (1) redefine substance abuse disorders, especially redefine the concept of abuse and harmful use; (2) increase the use of longitudinal and life-course studies with more adequate statistical methods such as latent growth modelling; (3) empirically test more specific and theoretically derived common factors and mechanisms of behavioural change processes; (4) better exploit cross-regional and cross-cultural differences.Funding agencies are urged to support these developments by specifically supporting interdisciplinary research along the lines specified above. This may include improved forms of international funding of groups of researchers from different countries, where each national group conducts a specific part of an integrated proposal. 2008 John Wiley & Sons, Ltd

Depression and Social Identity: An Integrative Review.

PubMed

Cruwys, Tegan; Haslam, S Alexander; Dingle, Genevieve A; Haslam, Catherine; Jetten, Jolanda

2014-08-01

Social relationships play a key role in depression. This is apparent in its etiology, symptomatology, and effective treatment. However, there has been little consensus about the best way to conceptualize the link between depression and social relationships. Furthermore, the extensive social-psychological literature on the nature of social relationships, and in particular, research on social identity, has not been integrated with depression research. This review presents evidence that social connectedness is key to understanding the development and resolution of clinical depression. The social identity approach is then used as a basis for conceptualizing the role of social relationships in depression, operationalized in terms of six central hypotheses. Research relevant to these hypotheses is then reviewed. Finally, we present an agenda for future research to advance theoretical and empirical understanding of the link between social identity and depression, and to translate the insights of this approach into clinical practice. © 2014 by the Society for Personality and Social Psychology, Inc.

Systems approaches in osteoarthritis: Identifying routes to novel diagnostic and therapeutic strategies.

PubMed

Mueller, Alan J; Peffers, Mandy J; Proctor, Carole J; Clegg, Peter D

2017-08-01

Systems orientated research offers the possibility of identifying novel therapeutic targets and relevant diagnostic markers for complex diseases such as osteoarthritis. This review demonstrates that the osteoarthritis research community has been slow to incorporate systems orientated approaches into research studies, although a number of key studies reveal novel insights into the regulatory mechanisms that contribute both to joint tissue homeostasis and its dysfunction. The review introduces both top-down and bottom-up approaches employed in the study of osteoarthritis. A holistic and multiscale approach, where clinical measurements may predict dysregulation and progression of joint degeneration, should be a key objective in future research. The review concludes with suggestions for further research and emerging trends not least of which is the coupled development of diagnostic tests and therapeutics as part of a concerted effort by the osteoarthritis research community to meet clinical needs. © 2017 The Authors. Journal of Orthopaedic Research Published by Wiley Periodicals, Inc. on behalf of Orthopaedic Research Society. J Orthop Res 35:1573-1588, 2017. © 2017 The Authors. Journal of Orthopaedic Research Published by Wiley Periodicals, Inc. on behalf of Orthopaedic Research Society.

Future opportunities and trends for e-infrastructures and life sciences: going beyond the grid to enable life science data analysis

PubMed Central

Duarte, Afonso M. S.; Psomopoulos, Fotis E.; Blanchet, Christophe; Bonvin, Alexandre M. J. J.; Corpas, Manuel; Franc, Alain; Jimenez, Rafael C.; de Lucas, Jesus M.; Nyrönen, Tommi; Sipos, Gergely; Suhr, Stephanie B.

2015-01-01

With the increasingly rapid growth of data in life sciences we are witnessing a major transition in the way research is conducted, from hypothesis-driven studies to data-driven simulations of whole systems. Such approaches necessitate the use of large-scale computational resources and e-infrastructures, such as the European Grid Infrastructure (EGI). EGI, one of key the enablers of the digital European Research Area, is a federation of resource providers set up to deliver sustainable, integrated and secure computing services to European researchers and their international partners. Here we aim to provide the state of the art of Grid/Cloud computing in EU research as viewed from within the field of life sciences, focusing on key infrastructures and projects within the life sciences community. Rather than focusing purely on the technical aspects underlying the currently provided solutions, we outline the design aspects and key characteristics that can be identified across major research approaches. Overall, we aim to provide significant insights into the road ahead by establishing ever-strengthening connections between EGI as a whole and the life sciences community. PMID:26157454

Future opportunities and trends for e-infrastructures and life sciences: going beyond the grid to enable life science data analysis.

PubMed

Duarte, Afonso M S; Psomopoulos, Fotis E; Blanchet, Christophe; Bonvin, Alexandre M J J; Corpas, Manuel; Franc, Alain; Jimenez, Rafael C; de Lucas, Jesus M; Nyrönen, Tommi; Sipos, Gergely; Suhr, Stephanie B

2015-01-01

With the increasingly rapid growth of data in life sciences we are witnessing a major transition in the way research is conducted, from hypothesis-driven studies to data-driven simulations of whole systems. Such approaches necessitate the use of large-scale computational resources and e-infrastructures, such as the European Grid Infrastructure (EGI). EGI, one of key the enablers of the digital European Research Area, is a federation of resource providers set up to deliver sustainable, integrated and secure computing services to European researchers and their international partners. Here we aim to provide the state of the art of Grid/Cloud computing in EU research as viewed from within the field of life sciences, focusing on key infrastructures and projects within the life sciences community. Rather than focusing purely on the technical aspects underlying the currently provided solutions, we outline the design aspects and key characteristics that can be identified across major research approaches. Overall, we aim to provide significant insights into the road ahead by establishing ever-strengthening connections between EGI as a whole and the life sciences community.

Impact and cost-effectiveness of current and future tuberculosis diagnostics: the contribution of modelling

PubMed Central

Houben, R.; Cohen, T.; Pai, M.; Cobelens, F.; Vassall, A.; Menzies, N. A.; Gomez, G. B.; Langley, I.; Squire, S. B.; White, R.

2014-01-01

SUMMARY The landscape of diagnostic testing for tuberculosis (TB) is changing rapidly, and stakeholders need urgent guidance on how to develop, deploy and optimize TB diagnostics in a way that maximizes impact and makes best use of available resources. When decisions must be made with only incomplete or preliminary data available, modelling is a useful tool for providing such guidance. Following a meeting of modelers and other key stakeholders organized by the TB Modelling and Analysis Consortium, we propose a conceptual framework for positioning models of TB diagnostics. We use that framework to describe modelling priorities in four key areas: Xpert® MTB/RIF scale-up, target product profiles for novel assays, drug susceptibility testing to support new drug regimens, and the improvement of future TB diagnostic models. If we are to maximize the impact and cost-effectiveness of TB diagnostics, these modelling priorities should figure prominently as targets for future research. PMID:25189546

Biomarkers and patient selection for PI3K/Akt/mTOR targeted therapies: current status and future directions.

PubMed

Bartlett, John M S

2010-11-01

The phosphatidylinositol 3-kinase (PI3K)/Akt/ mammalian target of rapamycin (mTOR) pathway regulates a broad spectrum of physiologic and pathologic processes. In breast cancer mutation, amplification, deletion, methylation, and posttranslational modifications lead to significant dysregulation of this pathway leading to more aggressive and potentially drug-resistant disease. Multiple novel agents, targeting different nodes within the pathway are currently under development by both commercial and academic partners. The key to the successful validation of these markers is selection of the appropriate patient groups using biomarkers. This article reviews current progress in this area, highlighting the key molecular alterations described in genes within the PI3K/Akt/mTOR pathway that may have an effect on response to current and future therapeutic interventions. Herein, gaps in current knowledge are highlighted and suggestions for future research directions given that may facilitate biomarker development in partnership with current drug development.

nanoSTAIR: a new strategic proposal to impulse standardization in nanotechnology research

NASA Astrophysics Data System (ADS)

López de Ipiña, J. M.; Salvi, O.; Hazebrouck, B.; Jovanovic, A.; Carre, F.; Saamanen, A.; Brouwer, D.; Schmitt, M.; Martin, S.

2015-05-01

Nanotechnology is considered one of the key technologies of the 21st century within Europe and a Key-Enabling Technology (KET) by Horizon 2020. Standardization has been identified in H2020 as one of the innovation-support measures by bridging the gap between research and the market, and helping the fast and easy transfer of research results to the European and international market. The development of new and improved standards requires high quality technical information, creating a fundamental interdependency between the standardization and research communities. In the frame of project nanoSTAIR (GA 319092), the present paper describes the European scenario on research and standardization in nanotechnology and presents a proposal of a European strategy (nanoSTAIR) to impulse direct “pipelines” between research and standardization. In addition, strategic actions focused on integration of standardization in the R&D projects, from the early stages of the design of a future business (Project Proposal), are also described.

Nano-enabled drug delivery: a research profile.

PubMed

Zhou, Xiao; Porter, Alan L; Robinson, Douglas K R; Shim, Min Suk; Guo, Ying

2014-07-01

Nano-enabled drug delivery (NEDD) systems are rapidly emerging as a key area for nanotechnology application. Understanding the status and developmental prospects of this area around the world is important to determine research priorities, and to evaluate and direct progress. Global research publication and patent databases provide a reservoir of information that can be tapped to provide intelligence for such needs. Here, we present a process to allow for extraction of NEDD-related information from these databases by involving topical experts. This process incorporates in-depth analysis of NEDD literature review papers to identify key subsystems and major topics. We then use these to structure global analysis of NEDD research topical trends and collaborative patterns, inform future innovation directions. This paper describes the process of how to derive nano-enabled drug delivery-related information from global research and patent databases in an effort to perform comprehensive global analysis of research trends and directions, along with collaborative patterns. Copyright © 2014 Elsevier Inc. All rights reserved.

Geoengineering with stratospheric aerosols: What do we not know after a decade of research?: GEOENGINEERING: WHAT DO WE NOT KNOW?

DOE PAGES

MacMartin, Douglas G.; Kravitz, Ben; Long, Jane C. S.; ...

2016-11-17

Any well-informed future decision on whether and how to deploy solar geoengineering requires balancing the impacts (both intended and unintended) of intervening in the climate against the impacts of not doing so. In spite of the tremendous progress in the last decade, the current state of knowledge remains insufficient to support an assessment of this balance, even for stratospheric aerosol geoengineering (SAG), arguably the best understood (practical) geoengineering method. We then articulate key unknowns associated with SAG, including both climate-science and design questions, as an essential step toward developing a future strategic research program that could address outstanding uncertainties.

Future Challenges and Opportunities in Online Prescription Drug Promotion Research Comment on "Trouble Spots in Online Direct-to-Consumer Prescription Drug Promotion: A Content Analysis of FDA Warning Letters".

PubMed

Southwell, Brian G; Rupert, Douglas J

2016-01-16

Despite increased availability of online promotional tools for prescription drug marketers, evidence on online prescription drug promotion is far from settled or conclusive. We highlight ways in which online prescription drug promotion is similar to conventional broadcast and print advertising and ways in which it differs. We also highlight five key areas for future research: branded drug website influence on consumer knowledge and behavior, interactive features on branded drug websites, mobile viewing of branded websites and mobile advertisements, online promotion and non-US audiences, and social media and medication decisions. © 2016 by Kerman University of Medical Sciences.

Utilizing NASA Earth Observations to investigate habitat suitability of the Cape Vulture in the Western Cape Province of South Africa

NASA Astrophysics Data System (ADS)

Gray, D.; Estes, M. G., Jr.; Griffin, R.; Estes, S. M.

2017-12-01

As the global urban population rapidly increases, many wild species lose habitat to human development. The Western Cape of South Africa contains one of Earth's 35 biodiversity hotspots, with remarkably high levels of species richness and endemism. Understanding the relationship between anthropogenic changes and key species in this region is crucial for conservation of its threatened ecosystems. The objective of this research was to investigate the effect that climate change and urbanization each have on habitat suitability of the Cape Vulture. This research utilized NASA satellite data and crowdsourced species sightings to model past, current, and future habitat suitability for this key species in the Western Cape. Data used from NASA Earth Observations included: Landsat 8- derived Land Cover, Modis Land Surface Temperature, Digital Elevation Models from the Shuttle Radar Topography Mission, and precipitation data which integrated in-situ stations with Infrared data. Species observations were sourced from the Global Biodiversity Information Facility online database. A geospatial modelling framework was used to generate maps of present, past and future suitable habitats for analysis and comparison. Changes in precipitation and temperature may be a factor in the extreme loss of habitat since 1995, and predict even more drastic loss in the future. This research provides insights on anthropogenic effects on a species' range which may be used to inform discussions of conservation as an element of environmentally sustainable development.

[Centennial retrospective on the evolution and development of nursing research in Taiwan].

PubMed

Tzeng, Wen-Chii; Lu, Meei-Shiow

2014-08-01

Nursing is a distinct branch of science. Nursing research is not only key to developing professional knowledge and but also to promoting nursing as an independent discipline. This paper describes the development and outcomes of nursing research over the past 100 years and then explores the factors that have influenced the focus of nursing research in the past. Findings may be applied to future efforts to promote nursing research. The authors hope that nurses integrate the best research evidence, the best clinical judgment, and the expectations of patients in order to provide the best quality of nursing care through reflection and praxis in nursing research.

Exploring evidence-policy linkages in health research plans: A case study from six countries

PubMed Central

Syed, Shamsuzzoha B; Hyder, Adnan A; Bloom, Gerald; Sundaram, Sandhya; Bhuiya, Abbas; Zhenzhong, Zhang; Kanjilal, Barun; Oladepo, Oladimeji; Pariyo, George; Peters, David H

2008-01-01

The complex evidence-policy interface in low and middle income country settings is receiving increasing attention. Future Health Systems (FHS): Innovations for Equity, is a research consortium conducting health systems explorations in six Asian and African countries: Bangladesh, India, China, Afghanistan, Uganda, and Nigeria. The cross-country research consortium provides a unique opportunity to explore the research-policy interface. Three key activities were undertaken during the initial phase of this five-year project. First, key considerations in strengthening evidence-policy linkages in health system research were developed by FHS researchers through workshops and electronic communications. Four key considerations in strengthening evidence-policy linkages are postulated: development context; research characteristics; decision-making processes; and stakeholder engagement. Second, these four considerations were applied to research proposals in each of the six countries to highlight features in the research plans that potentially strengthen the research-policy interface and opportunities for improvement. Finally, the utility of the approach for setting research priorities in health policy and systems research was reflected upon. These three activities yielded interesting findings. First, developmental consideration with four dimensions – poverty, vulnerabilities, capabilities, and health shocks – provides an entry point in examining research-policy interfaces in the six settings. Second, research plans focused upon on the ground realities in specific countries strengthens the interface. Third, focusing on research prioritized by decision-makers, within a politicized health arena, enhances chances of research influencing action. Lastly, early and continued engagement of multiple stakeholders, from local to national levels, is conducive to enhanced communication at the interface. The approach described has four main utilities: first, systematic analyses of research proposals using key considerations ensure such issues are incorporated into research proposals; second, the exact meaning, significance, and inter-relatedness of these considerations can be explored within the research itself; third, cross-country learning can be enhanced; and finally, translation of evidence into action may be facilitated. Health systems research proposals in low and middle income countries should include reflection on transferring research findings into policy. Such deliberations may be informed by employing the four key considerations suggested in this paper in analyzing research proposals. PMID:18331651

Quality and Diversity in VET [Vocational Education and Training] Research. Proceedings of the National Conference of the Australian Vocational Education and Training Research Association (AVETRA) (2nd, Melbourne, Australia, February 11-12, 1999).

ERIC Educational Resources Information Center

Australian Vocational Education and Training Research Association, Alexandria.

These proceedings consist of 43 presentations clustered into these key areas: position, strategy, contribution, and future issues; diversity of participation and contexts; issues in the workplace and learning settings; question of practitioners work; and questions of knowledge and methodology--all related to the themes of quality and diversity.…

The A, C, G, and T of Genome Assembly.

PubMed

Wajid, Bilal; Sohail, Muhammad U; Ekti, Ali R; Serpedin, Erchin

2016-01-01

Genome assembly in its two decades of history has produced significant research, in terms of both biotechnology and computational biology. This contribution delineates sequencing platforms and their characteristics, examines key steps involved in filtering and processing raw data, explains assembly frameworks, and discusses quality statistics for the assessment of the assembled sequence. Furthermore, the paper explores recent Ubuntu-based software environments oriented towards genome assembly as well as some avenues for future research.

The prospect of using large eddy and detached eddy simulations in engineering design, and the research required to get there

PubMed Central

Larsson, Johan; Wang, Qiqi

2014-01-01

In this paper, we try to look into the future to envision how large eddy and detached eddy simulations will be used in the engineering design process about 20–30 years from now. Some key challenges specific to the engineering design process are identified, and some of the critical outstanding problems and promising research directions are discussed. PMID:25024421

Reinforcement: Food Signals the Time and Location of Future Food

PubMed Central

Cowie, Sarah; Davison, Michael; Elliffe, Douglas

2011-01-01

It has long been understood that food deliveries may act as signals of future food location, and not only as strengtheners of prefood responding as the law of effect suggests. Recent research has taken this idea further—the main effect of food deliveries, or other “reinforcers”, may be signaling rather than strengthening. The present experiment investigated the ability of food deliveries to signal food contingencies across time after food. In Phase 1, the next food delivery was always equally likely to be arranged for a left- or a right-key response. Conditions were arranged such that the next food delivery was likely to occur either sooner on the left (or right) key, or sooner on the just-productive (or not-just-productive) key. In Phase 2, similar contingencies were arranged, but the last-food location was signaled by a red keylight. Preference, measured in 2-s bins across interfood intervals, was jointly controlled by the likely time and location of the next food delivery. In Phase 1, when any food delivery signaled a likely sooner next food delivery on a particular key, postfood preference was strongly toward that key, and moved toward the other key across the interreinforcer interval. In other conditions in which food delivery on the two keys signaled different subsequent contingencies, postfood preference was less extreme, and quickly moved toward indifference. In Phase 2, in all three conditions, initial preference was strongly toward the likely-sooner food key, and moved to the other key across the interfood interval. In both phases, at a more extended level of analysis, sequences of same-key food deliveries caused a small increase in preference for the just-productive key, suggesting the presence of a “reinforcement effect”, albeit one that was very small. PMID:21765546

Developing a Research Agenda to Optimize Diagnostic Imaging in the Emergency Department: An Executive Summary of the 2015 Academic Emergency Medicine Consensus Conference.

PubMed

Marin, Jennifer R; Mills, Angela M

2015-12-01

The 2015 Academic Emergency Medicine (AEM) consensus conference, "Diagnostic Imaging in the Emergency Department: A Research Agenda to Optimize Utilization," was held on May 12, 2015, with the goal of developing a high-priority research agenda on which to base future research. The specific aims of the conference were to: 1) understand the current state of evidence regarding emergency department (ED) diagnostic imaging utilization and identify key opportunities, limitations, and gaps in knowledge; 2) develop a consensus-driven research agenda emphasizing priorities and opportunities for research in ED diagnostic imaging; and 3) explore specific funding mechanisms available to facilitate research in ED diagnostic imaging. Over a 2-year period, the executive committee and other experts in the field convened regularly to identify specific areas in need of future research. Six content areas within emergency diagnostic imaging were identified prior to the conference and served as the breakout groups on which consensus was achieved: clinical decision rules; use of administrative data; patient-centered outcomes research; training, education, and competency; knowledge translation and barriers to imaging optimization; and comparative effectiveness research in alternatives to traditional computed tomography use. The executive committee invited key stakeholders to assist with planning and to participate in the consensus conference to generate a multidisciplinary agenda. There were 164 individuals involved in the conference spanning various specialties, including emergency medicine (EM), radiology, surgery, medical physics, and the decision sciences. This issue of AEM is dedicated to the proceedings of the 16th annual AEM consensus conference as well as original research related to emergency diagnostic imaging. © 2015 by the Society for Academic Emergency Medicine.

Projecting biodiversity and wood production in future forest landscapes: 15 key modeling considerations.

PubMed

Felton, Adam; Ranius, Thomas; Roberge, Jean-Michel; Öhman, Karin; Lämås, Tomas; Hynynen, Jari; Juutinen, Artti; Mönkkönen, Mikko; Nilsson, Urban; Lundmark, Tomas; Nordin, Annika

2017-07-15

A variety of modeling approaches can be used to project the future development of forest systems, and help to assess the implications of different management alternatives for biodiversity and ecosystem services. This diversity of approaches does however present both an opportunity and an obstacle for those trying to decide which modeling technique to apply, and interpreting the management implications of model output. Furthermore, the breadth of issues relevant to addressing key questions related to forest ecology, conservation biology, silviculture, economics, requires insights stemming from a number of distinct scientific disciplines. As forest planners, conservation ecologists, ecological economists and silviculturalists, experienced with modeling trade-offs and synergies between biodiversity and wood biomass production, we identified fifteen key considerations relevant to assessing the pros and cons of alternative modeling approaches. Specifically we identified key considerations linked to study question formulation, modeling forest dynamics, forest processes, study landscapes, spatial and temporal aspects, and the key response metrics - biodiversity and wood biomass production, as well as dealing with trade-offs and uncertainties. We also provide illustrative examples from the modeling literature stemming from the key considerations assessed. We use our findings to reiterate the need for explicitly addressing and conveying the limitations and uncertainties of any modeling approach taken, and the need for interdisciplinary research efforts when addressing the conservation of biodiversity and sustainable use of environmental resources. Copyright © 2017 Elsevier Ltd. All rights reserved.

Opportunities for research to improve employment for people with spinal cord injuries.

PubMed

Frieden, L; Winnegar, A J

2012-05-01

This paper reviews the literature pertaining to the employment of people who experience spinal cord injury (SCI) in the United States and recommending future research. The literature was reviewed with search terms such as SCI, employment, working from home and telework using databases in EBSCO, including Academic Search Complete and the American Psychological Association’s databases. Literature and findings on key factors related to employment illustrate the multiple dimensions of work environments, and health demands, that effect employment outcomes for people with SCI. Employment is important for people with SCI and valued in society. The literature reviewed indicates that researchers understand the work demands for people with SCI and may help to identify suitable supports, training and job opportunities. There remains a need for research focus on understanding future employment demands, necessary work skills, differing work environments and methods for increasing and preserving employment.

EURADOS strategic research agenda: vision for dosimetry of ionising radiation

PubMed Central

Rühm, W.; Fantuzzi, E.; Harrison, R.; Schuhmacher, H.; Vanhavere, F.; Alves, J.; Bottollier Depois, J. F.; Fattibene, P.; Knežević, Ž.; Lopez, M. A.; Mayer, S.; Miljanić, S.; Neumaier, S.; Olko, P.; Stadtmann, H.; Tanner, R.; Woda, C.

2016-01-01

Since autumn 2012, the European Radiation Dosimetry Group (EURADOS) has been developing its Strategic Research Agenda (SRA), which is intended to contribute to the identification of future research needs in radiation dosimetry in Europe. The present article summarises—based on input from EURADOS Working Groups (WGs) and Voting Members—five visions in dosimetry and defines key issues in dosimetry research that are considered important for the next decades. The five visions include scientific developments required towards (a) updated fundamental dose concepts and quantities, (b) improved radiation risk estimates deduced from epidemiological cohorts, (c) efficient dose assessment for radiological emergencies, (d) integrated personalised dosimetry in medical applications and (e) improved radiation protection of workers and the public. The SRA of EURADOS will be used as a guideline for future activities of the EURADOS WGs. A detailed version of the SRA can be downloaded as a EURADOS report from the EURADOS website (www.eurados.org). PMID:25752758

Intervention among Suicidal Men: Future Directions for Telephone Crisis Support Research.

PubMed

Hunt, Tara; Wilson, Coralie J; Woodward, Alan; Caputi, Peter; Wilson, Ian

2018-01-01

Telephone crisis support is a confidential, accessible, and immediate service that is uniquely set up to reduce male suicide deaths through crisis intervention. However, research focusing on telephone crisis support with suicidal men is currently limited. To highlight the need to address service delivery for men experiencing suicidal crisis, this perspective article identifies key challenges facing current telephone crisis support research and proposes that understanding of the role of telephone crisis helplines in supporting suicidal men may be strengthened by careful examination of the context of telephone crisis support, together with the impact this has on help-provision for male suicidal callers. In particular, the impact of the time- and information-poor context of telephone crisis support on crisis-line staff's identification of, and response to, male callers with thoughts of suicide is examined. Future directions for research in the provision of telephone crisis support for suicidal men are discussed.

Intervention among Suicidal Men: Future Directions for Telephone Crisis Support Research

PubMed Central

Hunt, Tara; Wilson, Coralie J.; Woodward, Alan; Caputi, Peter; Wilson, Ian

2018-01-01

Telephone crisis support is a confidential, accessible, and immediate service that is uniquely set up to reduce male suicide deaths through crisis intervention. However, research focusing on telephone crisis support with suicidal men is currently limited. To highlight the need to address service delivery for men experiencing suicidal crisis, this perspective article identifies key challenges facing current telephone crisis support research and proposes that understanding of the role of telephone crisis helplines in supporting suicidal men may be strengthened by careful examination of the context of telephone crisis support, together with the impact this has on help-provision for male suicidal callers. In particular, the impact of the time- and information-poor context of telephone crisis support on crisis-line staff’s identification of, and response to, male callers with thoughts of suicide is examined. Future directions for research in the provision of telephone crisis support for suicidal men are discussed. PMID:29404319

Trichuris muris research revisited: a journey through time.

PubMed

Hurst, Rebecca J M; Else, Kathryn J

2013-09-01

The mouse whipworm Trichuris muris has long been used as a tractable model of human Trichuriasis. Here we look back at the history of T. muris research; from the definition of the species and determination of its life cycle, through to the complex immune responses that we study today. We highlight the key research papers that have developed our understanding of immune responses to this parasite, and reflect on how original concepts have been transformed, as our knowledge of immunology has grown. Although we have a good understanding of host–parasite interactions in the context of the underlying cellular immunology, there are still many aspects of the biology of the Trichuris parasite that remain undefined. We predict that advances in parasite biology will be key in the future development of new and improved treatments for Trichuriasis.

Smart textiles: Challenges and opportunities

NASA Astrophysics Data System (ADS)

Cherenack, Kunigunde; van Pieterson, Liesbeth

2012-11-01

Smart textiles research represents a new model for generating creative and novel solutions for integrating electronics into unusual environments and will result in new discoveries that push the boundaries of science forward. A key driver for smart textiles research is the fact that both textile and electronics fabrication processes are capable of functionalizing large-area surfaces at very high speeds. In this article we review the history of smart textiles development, introducing the main trends and technological challenges faced in this field. Then, we identify key challenges that are the focus of ongoing research. We then proceed to discuss fundamentals of smart textiles: textile fabrication methods and textile interconnect lines, textile sensor, and output device components and integration of commercial components into textile architectures. Next we discuss representative smart textile systems and finally provide our outlook over the field and a prediction for the future.

Implementation science approaches for integrating eHealth research into practice and policy.

PubMed

Glasgow, Russell E; Phillips, Siobhan M; Sanchez, Michael A

2014-07-01

To summarize key issues in the eHealth field from an implementation science perspective and to highlight illustrative processes, examples and key directions to help more rapidly integrate research, policy and practice. We present background on implementation science models and emerging principles; discuss implications for eHealth research; provide examples of practical designs, measures and exemplar studies that address key implementation science issues; and make recommendations for ways to more rapidly develop and test eHealth interventions as well as future research, policy and practice. The pace of eHealth research has generally not kept up with technological advances, and many of our designs, methods and funding mechanisms are incapable of providing the types of rapid and relevant information needed. Although there has been substantial eHealth research conducted with positive short-term results, several key implementation and dissemination issues such as representativeness, cost, unintended consequences, impact on health inequities, and sustainability have not been addressed or reported. Examples of studies in several of these areas are summarized to demonstrate this is possible. eHealth research that is intended to translate into policy and practice should be more contextual, report more on setting factors, employ more responsive and pragmatic designs and report results more transparently on issues important to potential adopting patients, clinicians and organizational decision makers. We outline an alternative development and assessment model, summarize implementation science findings that can help focus attention, and call for different types of more rapid and relevant research and funding mechanisms. Published by Elsevier Ireland Ltd.

Determining Competencies for Frontline Sales Managers in For-Profit Organizations

ERIC Educational Resources Information Center

Busch, Tina Killough

2012-01-01

Practice in the sales profession and current competency research indicate salesperson competence is key to organizational competitive advantage. With models of selling evolving to respond to the marketplace, there are changes in the competency requirements and roles people must play for future success, resulting in the emergence of new kinds of…

Teaching for Present "and Future" Competency: A Productive Focus for Professional Learning

ERIC Educational Resources Information Center

Hipkins, Rosemary; McDowall, Sue

2013-01-01

The key competencies are a potentially transformative feature of the New Zealand Curriculum. However, the way in which they have been understood and implemented in schools points to tensions and challenges that may prevent them from acting as agents of curriculum change. One recent researcher/practitioner partnership developed materials that show…

Social Competencies Identification for Realization of Successful Engineering Practice

ERIC Educational Resources Information Center

Ivanova, Malinka

2012-01-01

Purpose: The aim of this paper is to identify the main social competencies that future engineers need to become recognized professionals. In the paper the key competencies for contemporary engineers are examined and the focus is given on the importance of social competencies for professional development. A competency research model is developed…

Enhancing Student Employability through Ethics-Based Outreach Activities and Open Educational Resources

ERIC Educational Resources Information Center

Lewis, David I.

2011-01-01

This paper reports on how science communication final year undergraduate research projects and educational internships can be utilised to provide opportunities for students to develop and utilise key employability skills. In the current difficult economic climate, the report "Working towards your future: Making the most of your time in higher…

Education and the Economy.

ERIC Educational Resources Information Center

Hollenbeck, Kevin M.

2001-01-01

The relationship between education and the United States (U.S.) economy was explored to identify research needed to inform employment policy in the future. Special attention was paid to the following topics: the state of education in the U.S.; key problems in grades K-12 that must be addressed; student achievement; inequity; costs of special…

A Review of Parent Education Programs for Parents of Children with Autism Spectrum Disorders

ERIC Educational Resources Information Center

Schultz, Tia R.; Schmidt, Carla T.; Stichter, Janine P.

2011-01-01

Benefits of parent education have been demonstrated for decades. However, there exists a lack of formative evaluation of parent education for parents of children with autism spectrum disorders (ASD), limiting the interpretation of ongoing and future research. To understand the current status, key characteristics, and evaluation methods of parent…

Innovation: Key to the future

NASA Technical Reports Server (NTRS)

1992-01-01

The NASA Marshall Space Flight Center Annual Report is presented. A description of research and development projects is included. Topics covered include: space science; space systems; transportation systems; astronomy and astrophysics; earth sciences; solar terrestrial physics; microgravity science; diagnostic and inspection system; information, electronic, and optical systems; materials and manufacturing; propulsion; and structures and dynamics.

Ocean science research is key for a sustainable future.

PubMed

Visbeck, Martin

2018-02-15

Human activity has already affected all parts of the ocean, with pollution increasing and fish-stocks plummeting. The UN's recent announcement of a Decade of Ocean Science provides a glimmer of hope, but scientists will need to work closely with decision-makers and society at large to get the ocean back on track.

Being Mindful about the Use of Mindfulness in Clinical Contexts

ERIC Educational Resources Information Center

Dimidjian, Sona; Kleiber, Blair

2013-01-01

Over the last 10 years, interest in the use and investigation of mindfulness-based interventions in clinical settings has expanded greatly. This commentary addresses key questions facing clinicians and researchers in order to undertake future work with rigor and care. We consider, in particular, questions regarding the definition of mindfulness,…

"We Think That's the Future": Curriculum Reform Initiatives in Higher Education

ERIC Educational Resources Information Center

Pegg, Ann

2014-01-01

This international research considered two key questions: (1) What self-scrutiny, strategies, planning and processes do universities with a successfully reformed curriculum undertake?; and (2) How do these universities measure and evaluate the impact of whole curriculum reform in relation to learning and teaching and the student experience?…

Developing Students' Understanding of Industrially Relevant Economic and Life Cycle Assessments

ERIC Educational Resources Information Center

Bode, Claudia J.; Chapman, Clint; Pennybaker, Atherly; Subramaniam, Bala

2017-01-01

Training future leaders to understand life cycle assessment data is critical for effective research, business, and sociopolitical decision-making. However, the technical nature of these life cycle reports often makes them challenging for students and other nonexperts to comprehend. Therefore, we outline here the key takeaways from recent economic…

Measuring Future Worker Productivity via Business Email Message Creation: Implications for Education

ERIC Educational Resources Information Center

Hagler, Barbara E.; Erthal, Margaret; Walzer, Dona; Anderson, Marcia A.

2009-01-01

Objective: This research was conducted to determine if relationships exist among college students' business email message productivity score and (a) email message quality score, (b) text keying method used to create email message, and (c) self-reported college English grade. Background: Email is increasingly the communication channel preferred for…

Mapping human dimensions of climate change research in the Canadian Arctic.

PubMed

Ford, James D; Bolton, Kenyon; Shirley, Jamal; Pearce, Tristan; Tremblay, Martin; Westlake, Michael

2012-12-01

This study maps current understanding and research trends on the human dimensions of climate change (HDCC) in the eastern and central Canadian Arctic. Developing a systematic literature review methodology, 117 peer reviewed articles are identified and examined using quantitative and qualitative methods. The research highlights the rapid expansion of HDCC studies over the last decade. Early scholarship was dominated by work documenting Inuit observations of climate change, with research employing vulnerability concepts and terminology now common. Adaptation studies which seek to identify and evaluate opportunities to reduce vulnerability to climate change and take advantage of new opportunities remain in their infancy. Over the last 5 years there has been an increase social science-led research, with many studies employing key principles of community-based research. We currently have baseline understanding of climate change impacts, adaptation, and vulnerability in the region, but key gaps are evident. Future research needs to target significant geographic disparities in understanding, consider risks and opportunities posed by climate change outside of the subsistence hunting sector, complement case study research with regional analyses, and focus on identifying and characterizing sustainable and feasible adaptation interventions.

Systems approaches in osteoarthritis: Identifying routes to novel diagnostic and therapeutic strategies

PubMed Central

Mueller, Alan J.; Peffers, Mandy J.; Proctor, Carole J.

2017-01-01

ABSTRACT Systems orientated research offers the possibility of identifying novel therapeutic targets and relevant diagnostic markers for complex diseases such as osteoarthritis. This review demonstrates that the osteoarthritis research community has been slow to incorporate systems orientated approaches into research studies, although a number of key studies reveal novel insights into the regulatory mechanisms that contribute both to joint tissue homeostasis and its dysfunction. The review introduces both top‐down and bottom‐up approaches employed in the study of osteoarthritis. A holistic and multiscale approach, where clinical measurements may predict dysregulation and progression of joint degeneration, should be a key objective in future research. The review concludes with suggestions for further research and emerging trends not least of which is the coupled development of diagnostic tests and therapeutics as part of a concerted effort by the osteoarthritis research community to meet clinical needs. © 2017 The Authors. Journal of Orthopaedic Research Published by Wiley Periodicals, Inc. on behalf of Orthopaedic Research Society. J Orthop Res 35:1573–1588, 2017. PMID:28318047

Progress in Aluminum Electrolysis Control and Future Direction for Smart Aluminum Electrolysis Plant

NASA Astrophysics Data System (ADS)

Zhang, Hongliang; Li, Tianshuang; Li, Jie; Yang, Shuai; Zou, Zhong

2017-02-01

The industrial aluminum reduction cell is an electrochemistry reactor that operates under high temperatures and highly corrosive conditions. However, these conditions have restricted the measurement of key control parameters, making the control of aluminum reduction cells a difficult problem in the industry. Because aluminum electrolysis control systems have a significant economic influence, substantial research has been conducted on control algorithms, control systems and information systems for aluminum reduction cells. This article first summarizes the development of control systems and then focuses on the progress made since 2000, including alumina concentration control, temperature control and electrolyte molecular ratio control, fault diagnosis, cell condition prediction and control system expansion. Based on these studies, the concept of a smart aluminum electrolysis plant is proposed. The frame construction, key problems and current progress are introduced. Finally, several future directions are discussed.

Highly Efficient Proteolysis Accelerated by Electromagnetic Waves for Peptide Mapping

PubMed Central

Chen, Qiwen; Liu, Ting; Chen, Gang

2011-01-01

Proteomics will contribute greatly to the understanding of gene functions in the post-genomic era. In proteome research, protein digestion is a key procedure prior to mass spectrometry identification. During the past decade, a variety of electromagnetic waves have been employed to accelerate proteolysis. This review focuses on the recent advances and the key strategies of these novel proteolysis approaches for digesting and identifying proteins. The subjects covered include microwave-accelerated protein digestion, infrared-assisted proteolysis, ultraviolet-enhanced protein digestion, laser-assisted proteolysis, and future prospects. It is expected that these novel proteolysis strategies accelerated by various electromagnetic waves will become powerful tools in proteome research and will find wide applications in high throughput protein digestion and identification. PMID:22379392

The four key characteristics of interpersonal emotion regulation.

PubMed

Niven, Karen

2017-10-01

Emotion researchers are increasingly interested in processes by which people influence others' feelings. Although one such process, interpersonal emotion regulation, has received particular attention in recent years, there remains confusion about exactly how to define this process. The present article aims to distinguish interpersonal emotion regulation from other, related processes by outlining its four key characteristics. Specifically, interpersonal emotion regulation is presented as a process of (i) regulation, that (ii) has an affective target, (iii) is deliberate, and (iv) has a social target. Considering these characteristics raises questions for future research concerning factors that may influence the process of interpersonal emotion regulation, why interpersonal emotion regulation sometimes fails, and whether interventions can improve people's use of interpersonal emotion regulation. Copyright © 2017 Elsevier Ltd. All rights reserved.

Discovering new variable stars at Key Stage 3

NASA Astrophysics Data System (ADS)

Chubb, Katy; Hood, Rosie; Wilson, Thomas; Holdship, Jonathan; Hutton, Sarah

2017-05-01

Details of the London pilot of the ‘Discovery Project’ are presented, where university-based astronomers were given the chance to pass on some real and applied knowledge of astronomy to a group of selected secondary school pupils. It was aimed at students in Key Stage 3 of their education, allowing them to be involved in real astronomical research at an early stage of their education, the chance to become the official discoverer of a new variable star, and to be listed in the International Variable Star Index database (The International Variable Star Index, Version 1.1, American Association of Variable Star Observers (AAVSO), 2016, http://aavso.org/vsx), all while learning and practising research-level skills. Future plans are discussed.

FutureTox III: Bridges for Translation | Science Inventory | US ...

EPA Pesticide Factsheets

The present document describes key discussion points and outcomes of a Society of Toxicology (SOT) Contemporary Concepts in Toxicology (CCT) Workshop, entitled FutureTox III1,2 that was held in Crystal City, Virginia, November 19-20, 2015. The workshop built on the many lessons learned from the first 10 years of TT21 and the first two workshops in the FutureTox series (for summary of FutureTox II see (Knudsen et al., 2015); for summary of FutureTox I see (Rowlands et al., 2014)). FutureTox III was attended in person and via webcast by more than 300 scientists from government research and regulatory agencies, research institutes, academia, and the chemical and pharmaceutical industries in Europe, Canada, and the United States. The meeting materials for FutureTox III, currently available to meeting registrants at http://www.toxicology.org/events/shm/cct/meetings.asp#upcoming-pnl-open, will be open to the public on November 29, 2016. At this workshop, participants reviewed and discussed the state of the science in toxicology and human risk and exposure assessment with a focus on moving TT21 science into the arena of regulatory decision-making. This manuscript describes the outcome of the FutureTox III 'contemporary concepts in toxicology' conference of the Society Toxicology, held November 2015 in Crystal City VA.

Challenges of integrating evidence into health policy and planning: linking multiple disciplinary approaches.

PubMed

Huckel Schneider, Carmen; Blyth, Fiona

2017-04-27

To explore the challenges that arise through the multidisciplinary nature of evidence informed policy making (EIPM). Type of program or service: Education and practice for EIPM. This article summarises and compares four disciplinary approaches to EIPM with highly contrasting starting points: behavioural science, policy science, critical theory and intervention research. Key insights and theories are highlighted to provide a gateway into each, and to complement what is already known about the evidence needs of policy makers in terms of high-quality, timely and well-communicated research evidence. The extension of the evidence based medicine approach to EIPM has created interest in the processes of use of evidence in health policy and planning. Research in this field has spanned multiple disciplines; however, the disciplines use very different research methods and begin with different basic assumptions. Thus, despite the multidisciplinary nature of EIPM, true interdisciplinary research and action remain a challenge. We conclude with a set of key questions that can be used as a gateway to interdisciplinary EIPM in the future.

Key strategies to improve systems for managing patient complaints within health facilities - what can we learn from the existing literature?

PubMed

Mirzoev, Tolib; Kane, Sumit

2018-01-01

Information from patient complaints - a widely accepted measure of patient satisfaction with services - can inform improvements in service quality, and contribute towards overall health systems performance. While analyses of data from patient complaints received much emphasis, there is limited published literature on key interventions to improve complaint management systems. The objectives are two-fold: first, to synthesise existing evidence and provide practical options to inform future policy and practice and, second, to identify key outstanding gaps in the existing literature to inform agenda for future research. We report results of review of the existing literature. Peer-reviewed published literature was searched in OVID Medline, OVID Global Health and PubMed. In addition, relevant citations from the reviewed articles were followed up, and we also report grey literature from the UK and the Netherlands. Effective interventions can improve collection of complaints (e.g. establishing easy-to-use channels and raising patients' awareness of these), analysis of complaint data (e.g. creating structures and spaces for analysis and learning from complaints data), and subsequent action (e.g. timely feedback to complainants and integrating learning from complaints into service quality improvement). No one single measure can be sufficient, and any intervention to improve patient complaint management system must include different components, which need to be feasible, effective, scalable, and sustainable within local context. Effective interventions to strengthen patient complaints systems need to be: comprehensive, integrated within existing systems, context-specific and cognizant of the information asymmetry and the unequal power relations between the key actors. Four gaps in the published literature represent an agenda for future research: limited understanding of contexts of effective interventions, absence of system-wide approaches, lack of evidence from low- and middle-income countries and absence of focused empirical assessments of behaviour of staff who manage patient complaints.

A systematic review of cost-effectiveness modeling of pharmaceutical therapies in neuropathic pain: variation in practice, key challenges, and recommendations for the future.

PubMed

Critchlow, Simone; Hirst, Matthew; Akehurst, Ron; Phillips, Ceri; Philips, Zoe; Sullivan, Will; Dunlop, Will C N

2017-02-01

Complexities in the neuropathic-pain care pathway make the condition difficult to manage and difficult to capture in cost-effectiveness models. The aim of this study is to understand, through a systematic review of previous cost-effectiveness studies, some of the key strengths and limitations in data and modeling practices in neuropathic pain. Thus, the aim is to guide future research and practice to improve resource allocation decisions and encourage continued investment to find novel and effective treatments for patients with neuropathic pain. The search strategy was designed to identify peer-reviewed cost-effectiveness evaluations of non-surgical, pharmaceutical therapies for neuropathic pain published since January 2000, accessing five key databases. All identified publications were reviewed and screened according to pre-defined eligibility criteria. Data extraction was designed to reflect key data challenges and approaches to modeling in neuropathic pain and based on published guidelines. The search strategy identified 20 cost-effectiveness analyses meeting the inclusion criteria, of which 14 had original model structures. Cost-effectiveness modeling in neuropathic pain is established and increasing across multiple jurisdictions; however, amongst these studies, there is substantial variation in modeling approach, and there are common limitations. Capturing the effect of treatments upon health outcomes, particularly health-related quality-of-life, is challenging, and the health effects of multiple lines of ineffective treatment, common for patients with neuropathic pain, have not been consistently or robustly modeled. To improve future economic modeling in neuropathic pain, further research is suggested into the effect of multiple lines of treatment and treatment failure upon patient outcomes and subsequent treatment effectiveness; the impact of treatment-emergent adverse events upon patient outcomes; and consistent and appropriate pain measures to inform models. The authors further encourage transparent reporting of inputs used to inform cost-effectiveness models, with robust, comprehensive and clear uncertainty analysis and, where feasible, open-source modeling is encouraged.

Key strategies to improve systems for managing patient complaints within health facilities – what can we learn from the existing literature?

PubMed Central

2018-01-01

ABSTRACT Background: Information from patient complaints – a widely accepted measure of patient satisfaction with services – can inform improvements in service quality, and contribute towards overall health systems performance. While analyses of data from patient complaints received much emphasis, there is limited published literature on key interventions to improve complaint management systems. Objectives: The objectives are two-fold: first, to synthesise existing evidence and provide practical options to inform future policy and practice and, second, to identify key outstanding gaps in the existing literature to inform agenda for future research. Methods: We report results of review of the existing literature. Peer-reviewed published literature was searched in OVID Medline, OVID Global Health and PubMed. In addition, relevant citations from the reviewed articles were followed up, and we also report grey literature from the UK and the Netherlands. Results: Effective interventions can improve collection of complaints (e.g. establishing easy-to-use channels and raising patients’ awareness of these), analysis of complaint data (e.g. creating structures and spaces for analysis and learning from complaints data), and subsequent action (e.g. timely feedback to complainants and integrating learning from complaints into service quality improvement). No one single measure can be sufficient, and any intervention to improve patient complaint management system must include different components, which need to be feasible, effective, scalable, and sustainable within local context. Conclusions: Effective interventions to strengthen patient complaints systems need to be: comprehensive, integrated within existing systems, context-specific and cognizant of the information asymmetry and the unequal power relations between the key actors. Four gaps in the published literature represent an agenda for future research: limited understanding of contexts of effective interventions, absence of system-wide approaches, lack of evidence from low- and middle-income countries and absence of focused empirical assessments of behaviour of staff who manage patient complaints. PMID:29658393

Analyzing the impacts of global trade and investment on non-communicable diseases and risk factors: a critical review of methodological approaches used in quantitative analyses.

PubMed

Cowling, Krycia; Thow, Anne Marie; Pollack Porter, Keshia

2018-05-24

A key mechanism through which globalization has impacted health is the liberalization of trade and investment, yet relatively few studies to date have used quantitative methods to investigate the impacts of global trade and investment policies on non-communicable diseases and risk factors. Recent reviews of this literature have found heterogeneity in results and a range of quality across studies, which may be in part attributable to a lack of conceptual clarity and methodological inconsistencies. This study is a critical review of methodological approaches used in the quantitative literature on global trade and investment and diet, tobacco, alcohol, and related health outcomes, with the objective of developing recommendations and providing resources to guide future robust, policy relevant research. A review of reviews, expert review, and reference tracing were employed to identify relevant studies, which were evaluated using a novel quality assessment tool designed for this research. Eight review articles and 34 quantitative studies were identified for inclusion. Important ways to improve this literature were identified and discussed: clearly defining exposures of interest and not conflating trade and investment; exploring mechanisms of broader relationships; increasing the use of individual-level data; ensuring consensus and consistency in key confounding variables; utilizing more sector-specific versus economy-wide trade and investment indicators; testing and adequately adjusting for autocorrelation and endogeneity when using longitudinal data; and presenting results from alternative statistical models and sensitivity analyses. To guide the development of future analyses, recommendations for international data sources for selected trade and investment indicators, as well as key gaps in the literature, are presented. More methodologically rigorous and consistent approaches in future quantitative studies on the impacts of global trade and investment policies on non-communicable diseases and risk factors can help to resolve inconsistencies of existing research and generate useful information to guide policy decisions.

The role of organizational structure in readiness for change: A conceptual integration.

PubMed

Benzer, Justin K; Charns, Martin P; Hamdan, Sami; Afable, Melissa

2017-02-01

The purpose of this review is to extend extant conceptualizations of readiness for change as an individual-level phenomenon. This review-of-reviews focuses on existing conceptual frameworks from the dissemination, implementation, quality improvement, and organizational transformation literatures in order to integrate theoretical rationales for how organization structure, a key dimension of the organizational context, may impact readiness for change. We propose that the organization structure dimensions of differentiation and integration impact readiness for change at the individual level of analysis by influencing four key concepts of relevance, legitimacy, perceived need for change, and resource allocation. We identify future research directions that focus on these four key concepts.

An overview of computer-based natural language processing

NASA Technical Reports Server (NTRS)

Gevarter, W. B.

1983-01-01

Computer based Natural Language Processing (NLP) is the key to enabling humans and their computer based creations to interact with machines in natural language (like English, Japanese, German, etc., in contrast to formal computer languages). The doors that such an achievement can open have made this a major research area in Artificial Intelligence and Computational Linguistics. Commercial natural language interfaces to computers have recently entered the market and future looks bright for other applications as well. This report reviews the basic approaches to such systems, the techniques utilized, applications, the state of the art of the technology, issues and research requirements, the major participants and finally, future trends and expectations. It is anticipated that this report will prove useful to engineering and research managers, potential users, and others who will be affected by this field as it unfolds.

Controls, Displays, and Information Transfer for General Aviation IFR Operations

NASA Technical Reports Server (NTRS)

Bergeron, H. P. (Editor); Shaughnessy, J. D. (Editor)

1983-01-01

The purpose of the workshop was to review and evaluate the work performed under the NASA Single Pilot IFR (SPIFR) program, to highlight and disseminate major research findings, and to provide a forum for industry, universities, and government to interact and discuss the future thrust of research in the SPIFR program. The presentations selected represent key elements of the SPIFR program. These elements are classified into five disciplinary areas: program definition, controls, displays, information transfer, and research simulation facilities. Emphasis is also placed on aircraft accident investigation.

Melanoma central nervous system metastases: current approaches, challenges, and opportunities

PubMed Central

Cohen, Justine V.; Tawbi, Hussain; Margolin, Kim A.; Amravadi, Ravi; Bosenberg, Marcus; Brastianos, Priscilla K.; Chiang, Veronica L.; de Groot, John; Glitza, Isabella C.; Herlyn, Meenhard; Holmen, Sheri L.; Jilaveanu, Lucia B.; Lassman, Andrew; Moschos, Stergios; Postow, Michael A.; Thomas, Reena; Tsiouris, John A.; Wen, Patrick; White, Richard M.; Turnham, Timothy; Davies, Michael A.; Kluger, Harriet M.

2017-01-01

Summary Melanoma central nervous system metastases are increasing, and the challenges presented by this patient population remain complex. In December 2015, the Melanoma Research Foundation and the Wistar Institute hosted the First Summit on Melanoma Central Nervous System (CNS) Metastases in Philadelphia, Pennsylvania. Here, we provide a review of the current status of the field of melanoma brain metastasis research; identify key challenges and opportunities for improving the outcomes in patients with melanoma brain metastases; and set a framework to optimize future research in this critical area. PMID:27615400

Indoor chemistry: research opportunities and challenges.

PubMed

Nazaroff, W W; Goldstein, A H

2015-08-01

In this editorial, we have highlighted key research opportunities and challenges in four topical themes for indoor chemistry: human occupants as agents influencing indoor chemistry; oxidative chemistry; surface phenomena; and semivolatile organic compounds. In each case, enough prior work has been done to demonstrate the importance of the theme and to create a foundation for future studies. Extensive achievements and ongoing progress in (outdoor) atmospheric chemistry—both in the analytical methods developed and in the scientific knowledge created—also contribute to a strong foundation from which to achieve rapid research progress in this exciting new domain.

[The present state and progress of researches on gait recognition].

PubMed

Xue, Zhaojun; Jin, Jingna; Ming, Dong; Wan, Baikun

2008-10-01

Recognition by gait is a new field for the biometric recognition technology. Its aim is to recognize people and detect physiological, pathological and mental characters by their walk style. The use of gait as a biometric for human identification is promising. The technique of gait recognition, as an attractive research area of biomedical information detection, attracts more and more attention. In this paper is introduced a survey of the basic theory, existing gait recognition methods and potential prospects. The latest progress and key factors of research difficulties are analyzed, and future researches are envisaged.

The A, C, G, and T of Genome Assembly

PubMed Central

Wajid, Bilal; Sohail, Muhammad U.; Ekti, Ali R.; Serpedin, Erchin

2016-01-01

Genome assembly in its two decades of history has produced significant research, in terms of both biotechnology and computational biology. This contribution delineates sequencing platforms and their characteristics, examines key steps involved in filtering and processing raw data, explains assembly frameworks, and discusses quality statistics for the assessment of the assembled sequence. Furthermore, the paper explores recent Ubuntu-based software environments oriented towards genome assembly as well as some avenues for future research. PMID:27247941

Literature Survey of Induced Traffic Due to Transport Cost Savings.

DTIC Science & Technology

1985-06-01

19. KEY WORDS (Continue on reveres aide If necessary and identify by block number) Induced traffic, benefit -cost analysis,discriminant analysis...currently " al"ilable t’ induced movement benefit . The reviewer focused on coal and grain . ’.rade. A jide range of sources were consulted and read...in order to find any research that had been done on induced movement benefit . Findings are sum- marized, and future research topics on feasible models

American Grand Strategy and the Future of U.S. Landpower

DTIC Science & Technology

2014-12-01

partners, a posting abroad with key allies, or attending graduate school and serv- ing on West Point’s faculty, which offer an opportunity to study in...of my job here is to ensure we resource faculty so they can continually deepen their studies and conduct important research so that we can...Interna- tional Studies , Gaoyue Fan, a senior research fellow at the PLA Military Science Academy said that, “If the U.S. military develops Air-Sea

Reflections on 'medical tourism' from the 2016 Global Healthcare Policy and Management Forum.

PubMed

Crooks, Valorie A; Ormond, Meghann; Jin, Ki Nam

2017-01-01

In October 2016, the Global Healthcare Policy and Management Forum was held at Yonsei University, Seoul, South Korea. The goal of the forum was to discuss the role of the state in regulating and supporting the development of medical tourism. Forum attendees came from 10 countries. In this short report article, we identify key lessons from the forum that can inform the direction of future scholarly engagement with medical tourism. In so doing, we reference on-going scholarly debates about this global health services practice that have appeared in multiple venues, including this very journal. Key questions for future research emerging from the forum include: who should be meaningfully involved in identifying and defining categories of those travelling across borders for health services and what risks exist if certain voices are underrepresented in such a process; who does and does not 'count' as a medical tourist and what are the implications of such quantitative assessments; why have researchers not been able to address pressing knowledge gaps regarding the health equity impacts of medical tourism; and how do national-level polices and initiatives shape the ways in which medical tourism is unfolding in specific local centres and clinics? This short report as an important time capsule that summarises the current state of medical tourism research knowledge as articulated by the thought leaders in attendance at the forum while also pushing for research growth.

A Hybrid Satellite-Terrestrial Approach to Aeronautical Communication Networks

NASA Technical Reports Server (NTRS)

Kerczewski, Robert J.; Chomos, Gerald J.; Griner, James H.; Mainger, Steven W.; Martzaklis, Konstantinos S.; Kachmar, Brian A.

2000-01-01

Rapid growth in air travel has been projected to continue for the foreseeable future. To maintain a safe and efficient national and global aviation system, significant advances in communications systems supporting aviation are required. Satellites will increasingly play a critical role in the aeronautical communications network. At the same time, current ground-based communications links, primarily very high frequency (VHF), will continue to be employed due to cost advantages and legacy issues. Hence a hybrid satellite-terrestrial network, or group of networks, will emerge. The increased complexity of future aeronautical communications networks dictates that system-level modeling be employed to obtain an optimal system fulfilling a majority of user needs. The NASA Glenn Research Center is investigating the current and potential future state of aeronautical communications, and is developing a simulation and modeling program to research future communications architectures for national and global aeronautical needs. This paper describes the primary requirements, the current infrastructure, and emerging trends of aeronautical communications, including a growing role for satellite communications. The need for a hybrid communications system architecture approach including both satellite and ground-based communications links is explained. Future aeronautical communication network topologies and key issues in simulation and modeling of future aeronautical communications systems are described.

A Flexible Socioeconomic Scenarios Framework for the Study of Plausible Arctic Futures

NASA Astrophysics Data System (ADS)

Reissell, A. K.; Peters, G. P.; Riahi, K.; Kroglund, M.; Lovecraft, A. L.; Nilsson, A. E.; Preston, B. L.; van Ruijven, B. J.

2016-12-01

Future developments of the Arctic region are associated with different drivers of change - climate, environmental, and socio-economic - and their interactions, and are highly uncertain. The uncertainty poses challenges for decision-making, calling for development of new analytical frameworks. Scenarios - coherent narratives describing potential futures, pathways to futures, and drivers of change along the way - can be used to explore the consequences of the key uncertainties, particularly in the long-term. In a participatory scenarios workshop, we used both top-down and bottom-up approaches for the development of a flexible socioeconomic scenarios framework. The top-down approach was linked to the global Integrated Assessment Modeling framework and its Shared Socio-Economic Pathways (SSPs), developing an Arctic extension of the set of five storylines on the main socioeconomic uncertainties in global climate change research. The bottom-up approach included participatory development of narratives originating from within the Arctic region. For extension of global SSPs to the regional level, we compared the key elements in the global SSPs (Population, Human Development, Economy & Lifestyle, Policies & Institutions, Technology, and Environment & Natural Resources) and key elements in the Arctic. Additional key elements for the Arctic scenarios include, for example, seasonal migration, the large role of traditional knowledge and culture, mixed economy, nested governance structure, human and environmental security, quality of infrastructure. The bottom-up derived results suggested that the scenarios developed independent of the SSPs could be mapped back to the SSPs to demonstrate consistency with respect to representing similar boundary conditions. The two approaches are complimentary, as the top-down approach can be used to set the global socio-economic and climate boundary conditions, and the bottom-up approach providing the regional context. One key uncertainty and driving force is the demand for resources (global or regional) that was mapped against the role of governance as well as adaptive and transformative capacity among actors within the Arctic. Resources demand has significant influence on the society, culture, economy and environment of the Arctic.

A new vision for the study of benign prostate disease: the NIDDK Prostate Research Strategic Plan.

PubMed

Mullins, Chris; Kaplan, Steven A

2009-03-01

The American population continues to enjoy a steady increase in life expectancy. A major goal for this population is to maintain and improve quality of life as it ages. For men a major source of age related health burden is benign disorders of the prostate which, despite much research, remain poorly defined and require greater advancement in prevention and treatment. Thus, there is a substantial need to develop a long-range vision to focus and promote efforts to better understand and manage benign prostate disease. In response the National Institute of Diabetes and Digestive and Kidney Diseases convened a panel of key opinion leaders including basic researchers, translational scientists, epidemiologists, and clinicians and clinical researchers to develop a comprehensive strategic plan to advance research in benign prostate disease. The overall mission statement of this effort is "To discuss, evaluate, and propose research needs and a long-range research agenda (ie a strategic plan) for NIDDK grant portfolios related to research into benign prostate disease." Implementation and practical application of this strategic plan will require a partnership of the scientific community, the Federal Government, and other public and private organizations and institutions. This focused group of research and thought leaders identified 4 major areas of key significance for future investigation: basic science, epidemiology/population based studies, translational opportunities and clinical sciences. Great opportunities are identified within these 4 areas to develop new insights, and translate findings for benign prostate diseases and related syndromes between the research laboratory and the clinical setting. The product of these efforts, the National Institute of Diabetes and Digestive and Kidney Diseases Prostate Research Strategic Plan, represents a blueprint that researchers and Federal Government can use to review where the field has been, define where the field is and, most importantly, identify where and how future research efforts should be directed. To accomplish this goal many priorities must be addressed, including the need to create more effective lines of communication among scientific disciplines to improve translation of research findings and ultimately advance patient treatment. The overall goals and missions of the National Institute of Diabetes and Digestive and Kidney Diseases Prostate Research Strategic Plan, along with key scientific recommendations and priorities for the major areas of focus, are summarized.

Rational Design of Tunnel Supports: An Interactive Graphics Based Analysis of the Support Requirements of Excavations in Jointed Rock Masses.

DTIC Science & Technology

1979-09-01

joint orientetion and joint slippage than to failure of the intact rock mass. Dixon (1971) noted the importance of including the confining influence of...dedicated computer. The area of research not covered by this investigation which holds promise for a future study is a detailed comparison of the results of...block data, type key "W". The program writes this data on Linc tapes for future retripval. This feature can be used to store the consolidated block

Satellite Networks: Architectures, Applications, and Technologies

NASA Technical Reports Server (NTRS)

Bhasin, Kul (Compiler)

1998-01-01

Since global satellite networks are moving to the forefront in enhancing the national and global information infrastructures due to communication satellites' unique networking characteristics, a workshop was organized to assess the progress made to date and chart the future. This workshop provided the forum to assess the current state-of-the-art, identify key issues, and highlight the emerging trends in the next-generation architectures, data protocol development, communication interoperability, and applications. Presentations on overview, state-of-the-art in research, development, deployment and applications and future trends on satellite networks are assembled.

DOE Office of Scientific and Technical Information (OSTI.GOV)

MacMartin, Douglas G.; Kravitz, Ben; Long, Jane C. S.

Any well-informed future decision on whether and how to deploy solar geoengineering requires balancing the impacts (both intended and unintended) of intervening in the climate against the impacts of not doing so. In spite of the tremendous progress in the last decade, the current state of knowledge remains insufficient to support an assessment of this balance, even for stratospheric aerosol geoengineering (SAG), arguably the best understood (practical) geoengineering method. We then articulate key unknowns associated with SAG, including both climate-science and design questions, as an essential step toward developing a future strategic research program that could address outstanding uncertainties.

Three-phase flow measurement in the petroleum industry

NASA Astrophysics Data System (ADS)

Thorn, R.; Johansen, G. A.; Hjertaker, B. T.

2013-01-01

The problem of how to accurately measure the flowrate of oil-gas-water mixtures in a pipeline remains one of the key challenges in the petroleum industry. This paper discusses why three-phase flow measurement is still important and why it remains a difficult problem to solve. The measurement strategies and principal base technologies currently used by commercial manufacturers are described, and research developments that could influence future flowmeter design are considered. Finally, future issues, which will need to be addressed by manufacturers and users of three-phase flowmeters, are discussed.

Co-Optimization of Fuels & Engines: Fuel Blendstocks with the Potential to Optimize Future Gasoline Engine Performance; Identification of Five Chemical Families for Detailed Evaluation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Farrell, John T; Holladay, John; Wagner, Robert

The U.S. Department of Energy's (DOE's) Co-Optimization of Fuels & Engines (Co-Optima) initiative is conducting the early-stage research needed to accelerate the market introduction of advanced fuel and engine technologies. The research includes both spark-ignition (SI) and compression-ignition (CI) combustion approaches, targeting applications that impact the entire on-road fleet (light-, medium-, and heavy-duty vehicles). The initiative's major goals include significant improvements in vehicle fuel economy, lower-cost pathways to reduce emissions, and leveraging diverse U.S. fuel resources. A key objective of Co-Optima's research is to identify new blendstocks that enhance current petroleum blending components, increase blendstock diversity, and provide refiners withmore » increased flexibility to blend fuels with the key properties required to optimize advanced internal combustion engines. This report identifies eight representative blendstocks from five chemical families that have demonstrated the potential to increase boosted SI engine efficiency, meet key fuel quality requirements, and be viable for production at commercial scale by 2025-2030.« less

NSF-Sponsored Summit on the Future of Undergraduate Geoscience Education: outcomes

NASA Astrophysics Data System (ADS)

Mosher, S.

2014-12-01

The NSF-sponsored Summit on the Future of Undergraduate Geoscience Education made major progress toward developing a collective community vision for the geosciences. A broad spectrum of the geoscience education community, ~200 educators from research universities/four and two year colleges, focused on preparation of undergraduates for graduate school and future geoscience careers, pedagogy, use of technology, broadening participation/retention of underrepresented groups, and preparation of K-12 science teachers. Participants agreed that key concepts, competencies and skills learned throughout the curriculum were more important than specific courses. Concepts included understanding Earth as complex, dynamic system, deep time, evolution of life, natural resources, energy, hazards, hydrogeology, surface processes, Earth materials and structure, and climate change. Skills/competencies included ability to think spatially and temporally, reason inductively and deductively, make and use indirect observations, engage in complex open, coupled systems thinking, and work with uncertainty, non-uniqueness, and incompleteness, as well as critical thinking, problem solving, communication, and ability to think like a scientist and continue to learn. Successful ways of developing these include collaborative, integrative projects involving teams, interdisciplinary projects, fieldwork and research experiences, as well as flipped classrooms and integration and interactive use of technology, including visualization, simulation, modeling and analysis of real data. Wider adoption of proven, effective best practices is our communities' main pedagogical challenge, and we focused on identifying implementation barriers. Preparation of future teachers in introductory and general geoscience courses by incorporating Next Generation Science Standards and using other sciences/math to solve real world geoscience problems should help increase diversity and number of future geoscientists and geoscience literacy. We also identified key elements of successful programs that attract and retain underrepresented groups, including providing financial support, reaching out to students in their communities, involving community members, incorporating role models, and mentoring.

Food for thought: food systems, livestock futures and animal health.

PubMed

Wilkinson, Angela

2013-12-01

Global food security, livestock production and animal health are inextricably bound. However, our focus on the future tends to disaggregate food and health into largely separate domains. Indeed, much foresight work is either food systems or health-based with little overlap in terms of predictions or narratives. Work on animal health is no exception. Part of the problem is the fundamental misunderstanding of the role, nature and impact of the modern futures tool kit. Here, I outline three key issues in futures research ranging from methodological confusion over the application of scenarios to the failure to effectively integrate multiple methodologies to the gap between the need for more evidence and power and control over futures processes. At its core, however, a better understanding of the narrative and worldview framing much of the futures work in animal health is required to enhance the value and impact of such exercises.

Implementation Science: Why it matters for the future of social work.

PubMed

Cabassa, Leopoldo J

2016-01-01

Bridging the gap between research and practice is a critical frontier for the future of social work. Integrating implementation science into social work can advance our profession's effort to bring research and practice closer together. Implementation science examines the factors, processes, and strategies that influence the uptake, use, and sustainability of empirically-supported interventions, practice innovations, and social policies in routine practice settings. The aims of this paper are to describe the key characteristics of implementation science, illustrate how implementation science matters to social work by describing several contributions this field can make to reducing racial and ethnic disparities in mental health care, and outline a training agenda to help integrate implementation science in graduate-level social work programs.

Implementation Science: Why it matters for the future of social work

PubMed Central

Cabassa, Leopoldo J.

2016-01-01

Bridging the gap between research and practice is a critical frontier for the future of social work. Integrating implementation science into social work can advance our profession’s effort to bring research and practice closer together. Implementation science examines the factors, processes, and strategies that influence the uptake, use, and sustainability of empirically-supported interventions, practice innovations, and social policies in routine practice settings. The aims of this paper are to describe the key characteristics of implementation science, illustrate how implementation science matters to social work by describing several contributions this field can make to reducing racial and ethnic disparities in mental health care, and outline a training agenda to help integrate implementation science in graduate-level social work programs. PMID:28216992

Preparing future faculty and professionals for public health careers.

PubMed

Koblinsky, Sally A; Hrapczynski, Katie M; Clark, Jane E

2015-03-01

Recent years have brought rapid growth in schools of public health and an increasing demand for public health practitioners. These trends highlight the need for innovative approaches to prepare doctoral graduates for academic and high-level practice positions. The University of Maryland's School of Public Health developed a "Preparing Future Faculty and Professionals" program to enrich the graduate education and professional development of its doctoral students. We describe the program's key elements, including foundational seminars to enhance students' knowledge and skills related to teaching, research, and service; activities designed to foster career exploration and increase competitiveness in the job market; and independent, faculty-mentored teaching and research experiences. We present a model for replicating the program and share student outcomes of participation.

Impact of space-based instruments on magnetic star research: past and future

NASA Astrophysics Data System (ADS)

Weiss, WW.; Neiner, C.; Wade, G. A.

2018-01-01

Magnetic stars are observed at a large variety of spectral ranges, frequently with photometric and spectroscopic techniques and on time scales ranging from a 'snap shot' to years, sometimes using data sets which are continuous over many months. The outcome of such observations has been discussed during this conference and many examples have been presented, demonstrating the high scientific significance and gains in our knowledge that result from these observations. A key question that should be addressed is, what are the advantages and requirements of space based research of magnetic stars, particularly in relation to ground based observations? And what are the drawbacks? What are the hopes for the future? In the following, we intend to present an overview that addresses these questions.

Tracking zebrafish larvae in group – Status and perspectives☆

PubMed Central

Martineau, Pierre R.; Mourrain, Philippe

2013-01-01

Video processing is increasingly becoming a standard procedure in zebrafish behavior investigations as it enables higher research throughput and new or better measures. This trend, fostered by the ever increasing performance-to-price ratio of the required recording and processing equipment, should be expected to continue in the foreseeable future, with video-processing based methods permeating more and more experiments and, as a result, expanding the very role of behavioral studies in zebrafish research. To assess whether the routine video tracking of zebrafish larvae directly in the Petri dish is a capability that can be expected in the near future, the key processing concepts are discussed and illustrated on published zebrafish studies when available or other animals when not. PMID:23707495

Moving the boundaries of international collaboration on clinical trials and QoL: experiences in oncology and legislation within the European Parliament.

PubMed

Bottomley, Andrew; Kirby, Tony; Bean, John; Walker, Julie

2013-02-01

The European Organisation for Research and Treatment of Cancer undertook another successful event with their third annual conference addressing quality of life matters in cancer clinical trials. More than 40 presentations were made over a 3-day period hosted at the European Parliament on 17-20 October 2012, in Brussels. The conference managed to get speakers and policy makers together to debate all the key issues in cancer clinical trials, design and reporting, including future policy and regulatory concerns. This meeting set the stage for future research and policy meetings to give greater visibility to quality of life as an outcome in clinical trials within the world of EU legislators.

The Paraná-Etendeka Continental Flood Basalt Province: A historical perspective of current knowledge and future research trends

NASA Astrophysics Data System (ADS)

Cañón-Tapia, Edgardo

2018-04-01

The development of ideas concerning Continental Flood Basalt Provinces is not new, and many studies were completed on specific provinces before the advent of plate tectonics. The Paraná-Etendeka Province is not an exception, and actually is an example of a province that has been thoroughly studied for > 100 years. In this work, I present a brief summary of various aspects of this province from a rather general point of view, including many references of difficult access to a reader not versed on the Portuguese language. Key features include the presence of alkaline volcanism along the edges of the main basin, before and after a markedly tholeiitic event, the uneven spatial distribution of eruptive products relative to the location of continental rupture, the apparent lack of a pattern of temporal activity across the whole province and the close relationship between the structure of the underlying sedimentary basin and the distribution of volcanic rocks. By bringing together information relevant to all of those key features, an evolutionary model emphasizing the role played by the changing local structure is outlined. This model is an example of how key observations (many of which were overlooked for > 50 years) provide the required impetus for the completion of future research that has the potential to substantially change the form in which this province has been visualized for at least the past 30 years.

Improving care and wellness in bipolar disorder: origins, evolution and future directions of a collaborative knowledge exchange network

PubMed Central

2012-01-01

The Collaborative RESearch team to study psychosocial factors in bipolar disorder (CREST.BD) is a multidisciplinary, cross-sectoral network dedicated to both fundamental research and knowledge exchange on bipolar disorder (BD). The core mission of the network is to advance the science and understanding of psychological and social issues associated with BD, improve the care and wellness of people living with BD, and strengthen services and supports for these individuals. CREST.BD bridges traditional and newer research approaches, particularly embracing community-based participatory research (CBPR) methods. Membership of CREST is broad, including academic researchers, people with BD, their family members and supports, and a variety of health care providers. Here, we describe the origins, evolution, approach to planning and evaluation and future vision for our network within the landscape of CBPR and integrated knowledge translation (KT), and explore the keys and challenges to success we have encountered working within this framework. PMID:22963889

DOE Office of Scientific and Technical Information (OSTI.GOV)

No, author

This report summarizes the outcome of U.S. Department of Energy (DOE) contract DE-OE0000543, requesting the design of a Cryptographic Key Management System (CKMS) for the secure management of cryptographic keys for the energy sector infrastructure. Prime contractor Sypris Electronics, in collaboration with Oak Ridge National Laboratories (ORNL), Electric Power Research Institute (EPRI), Valicore Technologies, and Purdue University's Center for Education and Research in Information Assurance and Security (CERIAS) and Smart Meter Integration Laboratory (SMIL), has designed, developed and evaluated the CKMS solution. We provide an overview of the project in Section 3, review the core contributions of all contractors inmore » Section 4, and discuss bene ts to the DOE in Section 5. In Section 6 we describe the technical construction of the CKMS solution, and review its key contributions in Section 6.9. Section 7 describes the evaluation and demonstration of the CKMS solution in different environments. We summarize the key project objectives in Section 8, list publications resulting from the project in Section 9, and conclude with a discussion on commercialization in Section 10 and future work in Section 11.« less

Provider competition and health care quality: challenges and opportunities for research.

PubMed

Wong, Herbert S; McNamara, Peggy; Greenberg, Warren

2004-06-01

On May 28, 2003, the Agency for Healthcare Research and Quality and the Federal Trade Commission co-sponsored an invitational conference entitled, "Provider Competition and Quality: Latest Findings and Implications for the Next Generation of Research." The main objectives of this conference were to share and discuss the latest findings on provider competition and quality, to identify implications for antitrust policy, and to develop an agenda for further research in this area. While it is impossible to completely capture the rich exchange of ideas and perspectives that transpired at the conference, we highlight several key themes that emerged and present a research agenda to guide future investigations.

Advancing Translational Research through Facility Design in Non-AMC Hospitals.

PubMed

Pati, Debajyoti; Pietrzak, Michael P; Harvey, Thomas E; Armstrong, Walter B; Clarke, Robert; Weissman, Neil J; Rapp, Paul E; Smith, Mark S; Fairbanks, Rollin J; Collins, Jeffreyg M

2013-01-01

This article aims to explore the future of translational research and its physical design implications for community hospitals and hospitals not attached to large centralized research platforms. With a shift in medical services delivery focus to community wellness, continuum of care, and comparative effectiveness research, healthcare research will witness increasing pressure to include community-based practitioners. The roundtable discussion group, comprising 14 invited experts from 10 institutions representing the fields of biomedical research, research administration, facility planning and design, facility management, finance, and environmental design research, examined the issue in a structured manner. The discussion was conducted at the Washington Hospital Center, MedStar Health, Washington, D.C. Institutions outside the AMCs will be increasingly targeted for future research. Three factors are crucial for successful research in non-AMC hospitals: operational culture, financial culture, and information culture. An operating culture geared towards creation, preservation, and protection of spaces needed for research; creative management of spaces for financial accountability; and a flexible information infrastructure at the system level that enables complete link of key programmatic areas to academic IT research infrastructure are critical to success of research endeavors. Hospital, interdisciplinary, leadership, planning, work environment.

Creating the Workforce of the Future: The STEM Interest and Proficiency Challenge. BHEF Research Brief

ERIC Educational Resources Information Center

Business-Higher Education Forum (NJ1), 2011

2011-01-01

A strong economy requires a highly educated workforce, especially in science, technology, engineering, and math (STEM) fields. In the United States, STEM degree production has stagnated, despite employment projections forecasting a 17% growth in the field over the next decade. Two key criteria influence progression through the STEM education…

E-Assessment: Challenges to the Legitimacy of VET Practitioners and Auditors

ERIC Educational Resources Information Center

Callan, Victor J.; Johnston, Margaret A.; Clayton, Berwyn; Poulsen, Alison L.

2016-01-01

This research examines what practitioners in vocational education and training (VET) organisations and external auditors judge to be the key issues in the current and future use of e-assessment. Applying the framework of legitimacy theory, the study examined the tensions around the use and growth of e-assessment in training organisations, and…

An Associational Research on Turkish Children's Environmentally Responsible Behaviors, Nature Relatedness, and Motive Concerns

ERIC Educational Resources Information Center

Bahar, Fatma; Sahin, Elvan

2017-01-01

Science education has changed in recent decades with respect to key issues faced in this century. These issues such as renewable energy, waste management, air quality, and biodiversity require dealing with the transition toward a sustainable future. Thus, to contribute to the reconceptualization of science education in a developing country, the…

Structuring Serendipity: Mentoring as a Component of Leadership Development Programs in Higher Education

ERIC Educational Resources Information Center

Bonebright, Denise A.

2014-01-01

The need to develop a pool of well-qualified future leaders is a key concern for human resource development scholars and practitioners in higher education. Research indicates that formal leadership development programs are most effective when they are based on experiential models. Mentoring is one experiential component that can enhance such…

Education and Development: The Issues and the Evidence. Education Research. Serial No. 6.

ERIC Educational Resources Information Center

Lewin, Keith M.

This literature review is divided into two main sections. The first part identifies key dimensions of the policy debate that will condition future patterns of investment in education. The themes chosen are the impact of recession, the effects of debt and structural adjustment programs on the resources available for education; the implications of…

Moving towards Optimising Demand-Led Learning: The 2005-2007 ECUANET Leonardo Da Vinci Project

ERIC Educational Resources Information Center

Dealtry, Richard; Howard, Keith

2008-01-01

Purpose: The purpose of this paper is to present the key project learning points and outcomes as a guideline for the future quality management of demand-led learning and development. Design/methodology/approach: The research methodology was based upon a corporate university blueprint architecture and browser toolkit developed by a member of the…

Global warming and extinctions of endemic species from biodiversity hotspots.

Treesearch

Jay R. Malcolm; Canran Liu; Ronald P. Neilson; Lara Hansen; Lee Hannah

2006-01-01

Global warming is a key threat to biodiversity, but few researchers have assessed the magnitude of this threat at the global scale. We used major vegetation types (biomes) as proxies for natural habitats and, based on projected future biome distributions under doubled-C02 climates, calculated changes in habitat areas and associated extinctions of...

Devolution and Higher Education: Impact and Future Trends. Research Report

ERIC Educational Resources Information Center

Trench, Alan

2008-01-01

Devolution to Scotland, Wales and (intermittently) Northern Ireland was one of the major constitutional reforms initiated by the new Labour Government when it took office in 1997. This was largely a political project, and one of devolution's key successes was largely to halt, at least for a while, political debates about the position of Scotland…

Nonmarket economic values of forest insect pests: An updated literature review

Treesearch

Randall S. Rosenberger; Lauren A. Bell; Patricia A. Champ; Eric. L. Smith

2012-01-01

This report updates the literature review and synthesis of economic valuation studies on the impacts of forest insect pests by Rosenberger and Smith (1997). A conceptual framework is presented to establish context for the studies. This report also discusses the concept of ecosystem services; identifies key elements of each study; examines areas of future research; and...

Influence of Instructional Practices on Secondary School Students' Achievement in Mathematics

ERIC Educational Resources Information Center

Nandwa, Odhiambo Marble; Wasike, Duncan Wekesa; Wanjala, Toili William

2015-01-01

Mathematics is a key subject which students cannot avoid if they have to lead a bright future. Despite the introduction and implementation of different teaching methods and strategies suggested by researchers the achievement of students in mathematics at school level has persistently been poor, hence the need to explore the influence of different…

Technology for America's Economic Growth, a New Direction To Build Economic Strength.

ERIC Educational Resources Information Center

Clinton, William J.; Gore, Albert, Jr.

Investing in technology is investing in America's future. U.S. technology must move in a new direction to build economic strength and spur economic growth. The traditional roles of support of basic science and mission-oriented technological research must be expanded, so that the federal government plays a key role in helping private firms develop…

Is Mobile Learning the Future of 21st Century Education? Educational Considerations from Various Perspectives

ERIC Educational Resources Information Center

Lahiri, Minakshi; Moseley, James L.

2012-01-01

One of the key trends currently affecting the practices of teaching, learning, and creative inquiry, as mentioned in "The 2011 Horizon Report," is that learners prefer flexibility and mobility. Mobile learning is gaining popularity as an emerging trend facilitating the process of teaching and learning in the 21st Century. Research indicates…

A New System for K-12 Education in Qatar. Research Brief

ERIC Educational Resources Information Center

Brewer, Dominic J.; Augustine, Catherine H.; Zellman, Gail L.; Ryan, Gery; Goldman, Charles A.; Stasz, Cathleen; Constant, Louay

2007-01-01

The leadership of the Arabian Gulf nation of Qatar, like that of many other countries, views education as the key to future economic, political, and social progress. Many have concluded that a country's ability to compete in the global economy and enable its citizens to take full advantage of technological advances relies on upgrading the quality…

75 FR 80853 - Designing a Digital Future: Federally Funded Research and Development in Networking and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-23

... general public. Such information includes, but is not limited to: A person's Social Security number; date... innovation is key to strengthening our economy and forming policy that works for the American people. PCAST... challenges are common across all of these sectors? c. What emerging innovations in these or other sectors...

Cui Bono? On the Relative Merits of Technology-Enhanced Learning and Teaching in Higher Education

ERIC Educational Resources Information Center

Mykhnenko, Vlad

2016-01-01

This article provides evidence from a 4-year longitudinal study on the comparative use of illustrative video podcasts during Economic Geography lectures vis-à-vis traditional educational methods in order to guide pedagogic practice and future research on the relative merits of technology-enhanced learning in higher education. Key benefits derived…

Understanding Dilemmas Faced by VET Teachers and Their Implications for International Students, Teachers and VET Institutions

ERIC Educational Resources Information Center

Nakar, Sonal

2016-01-01

This paper focuses on the voices and experiences of teachers, who are key stakeholders in the sustainability and future growth of vocational education and training (VET). It presents implications arising from qualitative research on the dilemmas that VET teachers face in teaching international students. In-depth interviewing with 15 VET teachers…

Marketing Your Educational Leadership Skills: How to Land the Job You Want. Second Edition

ERIC Educational Resources Information Center

Daresh, John C.; Schulte, Don

2011-01-01

In recent years, research that has identified instructional leadership as a key ingredient in effective schools has meant that attention has been directed increasingly at the ways in which future school administrators are being prepared. As a consequence, many universities have worked to develop administrator preparation programs that will enable…

Destinations and accommodations--how linked are they from a customer's perspective?

Treesearch

Mi Ran Kim; Christine Vogt; Annette Rummel

2008-01-01

Success in the hotel and tourism industry depends on understanding the key factors of customer satisfaction. Customer satisfaction leads to purchase repetition, intention to revisit, and potential increased future patronage of the hotel. The purpose of this research is to better understand (1) the factors that influence overnight accommodation decisions; (2) how these...

[Ecosystem services evaluation based on geographic information system and remote sensing technology: a review].

PubMed

Li, Wen-Jie; Zhang, Shi-Huang; Wang, Hui-Min

2011-12-01

Ecosystem services evaluation is a hot topic in current ecosystem management, and has a close link with human beings welfare. This paper summarized the research progress on the evaluation of ecosystem services based on geographic information system (GIS) and remote sensing (RS) technology, which could be reduced to the following three characters, i. e., ecological economics theory is widely applied as a key method in quantifying ecosystem services, GIS and RS technology play a key role in multi-source data acquisition, spatiotemporal analysis, and integrated platform, and ecosystem mechanism model becomes a powerful tool for understanding the relationships between natural phenomena and human activities. Aiming at the present research status and its inadequacies, this paper put forward an "Assembly Line" framework, which was a distributed one with scalable characteristics, and discussed the future development trend of the integration research on ecosystem services evaluation based on GIS and RS technologies.

A future perspective on technological obsolescenceat NASA, Langley Research Center

NASA Technical Reports Server (NTRS)

Mcintyre, Robert M.

1990-01-01

The present research effort was the first phase of a study to forecast whether technological obsolescence will be a problem for the engineers, scientists, and technicians at NASA Langley Research Center (LaRC). There were four goals of the research: to review the literature on technological obsolescence; to determine through interviews of division chiefs and branch heads Langley's perspective on future technological obsolescence; to begin making contacts with outside industries to find out how they view the possibility of technological obsolescence; and to make preliminary recommendations for dealing with the problem. A complete description of the findings of this research can be reviewed in a technical report in preparation. The following are a small subset of the key findings of the study: NASA's centers and divisions vary in their missions and because of this, in their capability to control obsolescence; research-oriented organizations within NASA are believed by respondents to keep up to date more than the project-oriented organizations; asked what are the signs of a professional's technological obsolescence, respondents had a variety of responses; top performing scientists were viewed as continuous learners, keeping up to date by a variety of means; when asked what incentives were available to aerospace technologists for keeping up to data, respondents specified a number of ideas; respondents identified many obstacles to professionals' keeping up to date in the future; and most respondents expressed some concern for the future of the professionals at NASA vis a vis the issue of professional obsolescence.

Advancing Evidence-Based Assessment in School Mental Health: Key Priorities for an Applied Research Agenda.

PubMed

Arora, Prerna G; Connors, Elizabeth H; George, Melissa W; Lyon, Aaron R; Wolk, Courtney B; Weist, Mark D

2016-12-01

Evidence-based assessment (EBA) is a critically important aspect of delivering high-quality, school-based mental health care for youth. However, research in this area is limited and additional applied research on how best to support the implementation of EBA in school mental health (SMH) is needed. Accordingly, this manuscript seeks to facilitate the advancement of research on EBA in SMH by reviewing relevant literature on EBA implementation in schools and providing recommendations for key research priorities. Given the limited number of published studies available, findings from child and adolescent mental health and implementation science research are also included to inform a robust and comprehensive research agenda on this topic. Based on this literature review, five priorities for research on EBA in SMH are outlined: (1) effective identification of assessment targets, (2) appropriate selection of assessment measures, (3) investigation of organizational readiness for EBA, (4) study of implementation support for EBA, and (5) promotion of EBA data integration and use. Each priority area includes recommended directions for future research. A comprehensive and robust research agenda is warranted to build the science and practice of implementing EBA in SMH. Specific directions for this agenda are offered.

Past, Present, and Future: A Science Program for the Arctic Ocean Linking Ancient and Contemporary Observations of Change Through Modeling

NASA Astrophysics Data System (ADS)

Coakley, Bernard; Edmonds, Henrietta N.; Frey, Karen; Gascard, Jean-Claude; Grebmeier, Jacqueline M.; Kassens, Heidemarie; Thiede, Jörn; Wegner, Carolyn

2007-07-01

A follow-up to the 2nd International Conference on Arctic Research Planning, 19-21 November 2007, Potsdam, Germany The Arctic Ocean is the missing piece for any global model. Records of processes at both long and short timescales will be necessary to predict the future evolution of the Arctic Ocean through what appears to be a period of rapid climate change. Ocean monitoring is impoverished without the long-timescale records available from paleoceanography and the boundary conditions that can be obtained from marine geology and geophysics. The past and the present are the key to our ability to predict the future.

Initial Investigation of Operational Concept Elements for NASA's NextGen-Airportal Project Research

NASA Technical Reports Server (NTRS)

Lohr, Gary; Lee, Jonathan; Poage, James L.; Tobias, Leonard

2009-01-01

The NextGen-Airportal Project is organized into three research focus areas: Safe and Efficient Surface Operations, Coordinated Arrival/Departure Operations Management, and Airportal Transition and Integration Management. The content in this document was derived from an examination of constraints and problems at airports for accommodating future increases in air traffic, and from an examination of capabilities envisioned for NextGen. The concepts are organized around categories of constraints and problems and therefore do not precisely match, but generally reflect, the research focus areas. The concepts provide a framework for defining and coordinating research activities that are, and will be, conducted by the NextGen-Airportal Project. The concepts will help the research activities function as an integrated set focused on future needs for airport operations and will aid aligning the research activities with NextGen key capabilities. The concepts are presented as concept elements with more detailed sub-elements under each concept element. For each concept element, the following topics are discussed: constraints and problems being addressed, benefit descriptions, required technology and infrastructure, and an initial list of potential research topics. Concept content will be updated and more detail added as the research progresses. The concepts are focused on enhancing airportal capacity and efficiency in a timeframe 20 to 25 years in the future, which is similar to NextGen's timeframe.

NAS Decadal Review Town Hall

NASA Astrophysics Data System (ADS)

The National Academies of Sciences, Engineering and Medicine is seeking community input for a study on the future of materials research (MR). Frontiers of Materials Research: A Decadal Survey will look at defining the frontiers of materials research ranging from traditional materials science and engineering to condensed matter physics. Please join members of the study committee for a town hall to discuss future directions for materials research in the United States in the context of worldwide efforts. In particular, input on the following topics will be of great value: progress, achievements, and principal changes in the R&D landscape over the past decade; identification of key MR areas that have major scientific gaps or offer promising investment opportunities from 2020-2030; and the challenges that MR may face over the next decade and how those challenges might be addressed. This study was requested by the Department of Energy and the National Science Foundation. The National Academies will issue a report in 2018 that will offer guidance to federal agencies that support materials research, science policymakers, and researchers in materials research and other adjoining fields. Learn more about the study at http://nas.edu/materials.

Lung Cancer Screening Participation: Developing a Conceptual Model to Guide Research

PubMed Central

Carter-Harris, Lisa; Davis, Lorie L.; Rawl, Susan M.

2017-01-01

Purpose To describe the development of a conceptual model to guide research focused on lung cancer screening participation from the perspective of the individual in the decision-making process. Methods Based on a comprehensive review of empirical and theoretical literature, a conceptual model was developed linking key psychological variables (stigma, medical mistrust, fatalism, worry, and fear) to the health belief model and precaution adoption process model. Results Proposed model concepts have been examined in prior research of either lung or other cancer screening behavior. To date, a few studies have explored a limited number of variables that influence screening behavior in lung cancer specifically. Therefore, relationships among concepts in the model have been proposed and future research directions presented. Conclusion This proposed model is an initial step to support theoretically based research. As lung cancer screening becomes more widely implemented, it is critical to theoretically guide research to understand variables that may be associated with lung cancer screening participation. Findings from future research guided by the proposed conceptual model can be used to refine the model and inform tailored intervention development. PMID:28304262

Lung Cancer Screening Participation: Developing a Conceptual Model to Guide Research.

PubMed

Carter-Harris, Lisa; Davis, Lorie L; Rawl, Susan M

2016-11-01

To describe the development of a conceptual model to guide research focused on lung cancer screening participation from the perspective of the individual in the decision-making process. Based on a comprehensive review of empirical and theoretical literature, a conceptual model was developed linking key psychological variables (stigma, medical mistrust, fatalism, worry, and fear) to the health belief model and precaution adoption process model. Proposed model concepts have been examined in prior research of either lung or other cancer screening behavior. To date, a few studies have explored a limited number of variables that influence screening behavior in lung cancer specifically. Therefore, relationships among concepts in the model have been proposed and future research directions presented. This proposed model is an initial step to support theoretically based research. As lung cancer screening becomes more widely implemented, it is critical to theoretically guide research to understand variables that may be associated with lung cancer screening participation. Findings from future research guided by the proposed conceptual model can be used to refine the model and inform tailored intervention development.

Climate Change, Permafrost and Infrastructure: Task Force Report of the U.S. Arctic Research Commission

NASA Astrophysics Data System (ADS)

Brigham, L. W.; Nelson, F. E.

2003-12-01

During 2002 the U.S. Arctic Research Commission chartered a task force on climate change, permafrost and infrastructure impacts. The task force was asked to identify key issues and research needs to foster a greater understanding of global change impacts on permafrost in the Arctic and their importance to natural and human systems. Permafrost was found to play three key roles in the context of climatic change: as a record keeper by functioning as a temperature archive; as a translator of climate change through subsidence and related impacts; and, as a facilitator of further change through its impacts on the global carbon cycle. Evidence of widespread warming of permafrost and observations of thawing have serious implications for Alaska's transportation network, for the trans-Alaska pipeline, and for nearly 100,000 Alaskans living in areas of permafrost. These impacts resulting from changing permafrost must be met by a timely, well-informed, and coordinated response by a host of federal and state organizations. Key task force findings include: requirements for a dedicated U.S. federal permafrost research program; data management needs; baseline permafrost mapping in Alaska; basic permafrost research focusing on process studies and modeling; and, applied permafrost research on design criteria and contaminants in permafrost environments. This report to the Commissioners makes specific recommendations to seven federal agencies, the State of Alaska, and the National Research Council. These recommendations will be incorporated in future Arctic research planning documents of the U.S. Arctic Research Commission.

Future Scenarios as a Research Tool: Investigating Climate Change Impacts, Adaptation Options and Outcomes for the Great Barrier Reef, Australia.

PubMed

Evans, Louisa S; Hicks, Christina C; Fidelman, Pedro; Tobin, Renae C; Perry, Allison L

2013-01-01

Climate change is a significant future driver of change in coastal social-ecological systems. Our knowledge of impacts, adaptation options, and possible outcomes for marine environments and coastal industries is expanding, but remains limited and uncertain. Alternative scenarios are a way to explore potential futures under a range of conditions. We developed four alternative future scenarios for the Great Barrier Reef and its fishing and tourism industries positing moderate and more extreme (2-3 °C above pre-industrial temperatures) warming for 2050 and contrasting 'limited' and 'ideal' ecological and social adaptation. We presented these scenarios to representatives of key stakeholder groups to assess the perceived viability of different social adaptation options to deliver desirable outcomes under varied contexts.

Guidance, Navigation, and Control Technology Assessment for Future Planetary Science Missions

NASA Technical Reports Server (NTRS)

Beauchamp, Pat; Cutts, James; Quadrelli, Marco B.; Wood, Lincoln J.; Riedel, Joseph E.; McHenry, Mike; Aung, MiMi; Cangahuala, Laureano A.; Volpe, Rich

2013-01-01

Future planetary explorations envisioned by the National Research Council's (NRC's) report titled Vision and Voyages for Planetary Science in the Decade 2013-2022, developed for NASA Science Mission Directorate (SMD) Planetary Science Division (PSD), seek to reach targets of broad scientific interest across the solar system. This goal requires new capabilities such as innovative interplanetary trajectories, precision landing, operation in close proximity to targets, precision pointing, multiple collaborating spacecraft, multiple target tours, and advanced robotic surface exploration. Advancements in Guidance, Navigation, and Control (GN&C) and Mission Design in the areas of software, algorithm development and sensors will be necessary to accomplish these future missions. This paper summarizes the key GN&C and mission design capabilities and technologies needed for future missions pursuing SMD PSD's scientific goals.

Retail food environments research in Canada: A scoping review.

PubMed

Minaker, Leia M; Shuh, Alanna; Olstad, Dana L; Engler-Stringer, Rachel; Black, Jennifer L; Mah, Catherine L

2016-06-09

The field of retail food environments research is relatively new in Canada. The objective of this scoping review is to provide an overview of retail food environments research conducted before July 2015 in Canada. Specifically, this review describes research foci and key findings, identifies knowledge gaps and suggests future directions for research. A search of published literature concerning Canadian investigations of retail food environment settings (food stores, restaurants) was conducted in July 2015 using PubMed, Web of Science, Scopus, PsychInfo and ERIC. Studies published in English that reported qualitative or quantitative data on any aspect of the retail food environment were included, as were conceptual papers and commentaries. Eighty-eight studies were included in this review and suggest that the field of retail food environments research is rapidly expanding in Canada. While only 1 paper was published before 2005, 66 papers were published between 2010 and 2015. Canadian food environments research typically assessed either the socio-economic patterning of food environments (n = 28) or associations between retail food environments and diet, anthropometric or health outcomes (n = 33). Other papers profiled methodological research, qualitative studies, intervention research and critical commentaries (n = 27). Key gaps in the current literature include measurement inconsistency among studies and a lack of longitudinal and intervention studies. Retail food environments are a growing topic of research, policy and program development in Canada. Consistent methods (where appropriate), longitudinal and intervention research, and close partnerships between researchers and key stakeholders would greatly advance the field of retail food environments research in Canada.

[Research progress of multi-model medical image fusion and recognition].

PubMed

Zhou, Tao; Lu, Huiling; Chen, Zhiqiang; Ma, Jingxian

2013-10-01

Medical image fusion and recognition has a wide range of applications, such as focal location, cancer staging and treatment effect assessment. Multi-model medical image fusion and recognition are analyzed and summarized in this paper. Firstly, the question of multi-model medical image fusion and recognition is discussed, and its advantage and key steps are discussed. Secondly, three fusion strategies are reviewed from the point of algorithm, and four fusion recognition structures are discussed. Thirdly, difficulties, challenges and possible future research direction are discussed.

Elicitation of State and Local User Needs for Future Moderate Resolution Earth Observations: The AmericaView Contribution

NASA Astrophysics Data System (ADS)

French, N. H. F.; Lawrence, R. L.

2017-12-01

AmericaView is a nationwide partnership of remote sensing scientists who support the use of Landsat and other public domain remotely sensed data through applied remote sensing research, K-12 and higher STEM education, workforce development, and technology transfer. The national AmericaView program currently has active university-lead members in 39 states, each of which has a "stateview" consortium consisting of some combination of university, agency, non-profit, and other members. This "consortium of consortia" has resulted in a strong and unique nationwide network of remote sensing practitioners. AmericaView has used this network to contribute to the USGS Requirements Capabilities & Analysis for Earth Observations. Participating states have conducted interviews of key remote sensing end users across the country to provide key input at the state and local level for the design and implementation of future U.S. moderate resolution Earth observations.

Prehospital Trauma Care in Singapore.

PubMed

Ho, Andrew Fu Wah; Chew, David; Wong, Ting Hway; Ng, Yih Yng; Pek, Pin Pin; Lim, Swee Han; Anantharaman, Venkataraman; Hock Ong, Marcus Eng

2015-01-01

Prehospital emergency care in Singapore has taken shape over almost a century. What began as a hospital-based ambulance service intended to ferry medical cases was later complemented by an ambulance service under the Singapore Fire Brigade to transport trauma cases. The two ambulance services would later combine and come under the Singapore Civil Defence Force. The development of prehospital care systems in island city-state Singapore faces unique challenges as a result of its land area and population density. This article defines aspects of prehospital trauma care in Singapore. It outlines key historical milestones and current initiatives in service, training, and research. It makes propositions for the future direction of trauma care in Singapore. The progress Singapore has made given her circumstances may serve as lessons for the future development of prehospital trauma systems in similar environments. Key words: Singapore; trauma; prehospital emergency care; emergency medical services.

Parasites as drivers of key processes in aquatic ecosystems: Facts and future directions.

PubMed

Sures, B; Nachev, M; Pahl, M; Grabner, D; Selbach, C

2017-09-01

Despite the advances in our understanding of the ecological importance of parasites that we have made in recent years, we are still far away from having a complete picture of the ecological implications connected to parasitism. In the present paper we highlight key issues that illustrate (1) important contributions of parasites to biodiversity, (2) their integral role in ecosystems, (3) as well as their ecological effects as keystone species (4) and in biological invasion processes. By using selected examples from aquatic ecosystems we want to provide an insight and generate interest into the topic, and want to show directions for future research in the field of ecological parasitology. This may help to convince more parasitologists and ecologists contributing and advancing our understanding of the complex and fascinating interplay of parasites, hosts and ecosystems. Copyright © 2017 Elsevier Inc. All rights reserved.

The future challenge for aeropropulsion

NASA Technical Reports Server (NTRS)

Rosen, Robert; Bowditch, David N.

1992-01-01

NASA's research in aeropropulsion is focused on improving the efficiency, capability, and environmental compatibility for all classes of future aircraft. The development of innovative concepts, and theoretical, experimental, and computational tools provide the knowledge base for continued propulsion system advances. Key enabling technologies include advances in internal fluid mechanics, structures, light-weight high-strength composite materials, and advanced sensors and controls. Recent emphasis has been on the development of advanced computational tools in internal fluid mechanics, structural mechanics, reacting flows, and computational chemistry. For subsonic transport applications, very high bypass ratio turbofans with increased engine pressure ratio are being investigated to increase fuel efficiency and reduce airport noise levels. In a joint supersonic cruise propulsion program with industry, the critical environmental concerns of emissions and community noise are being addressed. NASA is also providing key technologies for the National Aerospaceplane, and is studying propulsion systems that provide the capability for aircraft to accelerate to and cruise in the Mach 4-6 speed range. The combination of fundamental, component, and focused technology development underway at NASA will make possible dramatic advances in aeropropulsion efficiency and environmental compatibility for future aeronautical vehicles.

Animal health aspects of adaptation to climate change: beating the heat and parasites in a warming Europe.

PubMed

Skuce, P J; Morgan, E R; van Dijk, J; Mitchell, M

2013-06-01

Weather patterns in northern European regions have changed noticeably over the past several decades, featuring warmer, wetter weather with more extreme events. The climate is projected to continue on this trajectory for the foreseeable future, even under the most modest warming scenarios. Such changes will have a significant impact on livestock farming, both directly through effects on the animals themselves, and indirectly through changing exposure to pests and pathogens. Adaptation options aimed at taking advantage of new opportunities and/or minimising the risks of negative impacts will, in themselves, have implications for animal health and welfare. In this review, we consider the potential consequences of future intensification of animal production, challenges associated with indoor and outdoor rearing of animals and aspects of animal transportation as key examples. We investigate the direct and indirect effects of climate change on the epidemiology of important livestock pathogens, with a particular focus on parasitic infections, and the likely animal health consequences associated with selected adaptation options. Finally, we attempt to identify key gaps in our knowledge and suggest future research priorities.

Designing augmentative and alternative communication applications: the results of focus groups with speech-language pathologists and parents of children with autism spectrum disorder.

PubMed

Boster, Jamie B; McCarthy, John W

2018-05-01

The purpose of this study was to gain insight from speech-language pathologists (SLPs) and parents of children with autism spectrum disorder (ASD) regarding appealing features of augmentative and alternative communication (AAC) applications. Two separate 1-hour focus groups were conducted with 8 SLPs and 5 parents of children with ASD to identify appealing design features of AAC Apps, their benefits and potential concerns. Participants were shown novel interface designs for communication mode, play mode and incentive systems. Participants responded to poll questions and provided benefits and drawbacks of the features as part of structured discussion. SLPs and parents identified a range of appealing features in communication mode (customization, animation and colour-coding) as well as in play mode (games and videos). SLPs preferred interfaces that supported motor planning and instruction while parents preferred those features such as character assistants that would appeal to their child. Overall SLPs and parents agreed on features for future AAC Apps. SLPs and parents have valuable input in regards to future AAC app design informed by their experiences with children with ASD. Both groups are key stakeholders in the design process and should be included in future design and research endeavors. Implications for Rehabilitation AAC applications for the iPad are often designed based on previous devices without consideration of new features. Ensuring the design of new interfaces are appealing and beneficial for children with ASD can potentially further support their communication. This study demonstrates how key stakeholders in AAC including speech language pathologists and parents can provide information to support the development of future AAC interface designs. Key stakeholders may be an untapped resource in the development of future AAC interfaces for children with ASD.

Female arsonists: key features, psychopathologies, and treatment needs.

PubMed

Gannon, Theresa A

2010-01-01

Female-perpetrated arson is a topic that has received relatively little research attention from either psychiatrists or psychologists. In this review, available research regarding the characteristics, psychopathologies, and current treatment efforts with female arsonists is reviewed. Evaluation of current research with female arsonists suggests that very few researchers have compared female arsonists either to suitable female offender control groups or male arsons. Consequently, clinical knowledge and practice regarding female-perpetrated arson is underdeveloped relative to both other areas of forensic-clinical psychiatry and to knowledge of male arsonists. Suggestions are made for translating current research into arson interventions with female arsonists. Core arenas for future treatment and research provision are also highlighted.

What is big data? A consensual definition and a review of key research topics

NASA Astrophysics Data System (ADS)

De Mauro, Andrea; Greco, Marco; Grimaldi, Michele

2015-02-01

Although Big Data is a trending buzzword in both academia and the industry, its meaning is still shrouded by much conceptual vagueness. The term is used to describe a wide range of concepts: from the technological ability to store, aggregate, and process data, to the cultural shift that is pervasively invading business and society, both drowning in information overload. The lack of a formal definition has led research to evolve into multiple and inconsistent paths. Furthermore, the existing ambiguity among researchers and practitioners undermines an efficient development of the subject. In this paper we have reviewed the existing literature on Big Data and analyzed its previous definitions in order to pursue two results: first, to provide a summary of the key research areas related to the phenomenon, identifying emerging trends and suggesting opportunities for future development; second, to provide a consensual definition for Big Data, by synthesizing common themes of existing works and patterns in previous definitions.

Modeling Pathways of Character Development across the First Three Decades of Life: An Application of Integrative Data Analysis Techniques to Understanding the Development of Hopeful Future Expectations.

PubMed

Callina, Kristina Schmid; Johnson, Sara K; Tirrell, Jonathan M; Batanova, Milena; Weiner, Michelle B; Lerner, Richard M

2017-06-01

There were two purposes of the present research: first, to add to scholarship about a key character virtue, hopeful future expectations; and second, to demonstrate a recent innovation in longitudinal methodology that may be especially useful in enhancing the understanding of the developmental course of hopeful future expectations and other character virtues that have been the focus of recent scholarship in youth development. Burgeoning interest in character development has led to a proliferation of short-term, longitudinal studies on character. These data sets are sometimes limited in their ability to model character development trajectories due to low power or relatively brief time spans assessed. However, the integrative data analysis approach allows researchers to pool raw data across studies in order to fit one model to an aggregated data set. The purpose of this article is to demonstrate the promises and challenges of this new tool for modeling character development. We used data from four studies evaluating youth character strengths in different settings to fit latent growth curve models of hopeful future expectations from participants aged 7 through 26 years. We describe the analytic strategy for pooling the data and modeling the growth curves. Implications for future research are discussed in regard to the advantages of integrative data analysis. Finally, we discuss issues researchers should consider when applying these techniques in their own work.

Treating Insomnia: A Review of Patient Perceptions Toward Treatment.

PubMed

Cheung, Janet M Y; Bartlett, Delwyn J; Armour, Carol L; Saini, Bandana

2016-01-01

Patient views about their treatment for insomnia often dictate outcome. This review explores the literature relating to the patients' global perceptions toward treatment for insomnia. A strategic literature search was conducted using five databases (PubMed, CINAHL, Medline, PsycINFO, and Embase). The 57 research articles included for this review were mapped out chronologically across three key stages of treatment-seeking (pretreatment appraisal, actual treatment experiences, and posttreatment evaluation). Patient perceptions played an important role across these three key stages and influenced subsequent health behaviors such as the initiation of help-seeking, treatment uptake, treatment adherence, and treatment adjustment. Patients' perceptions toward treatment were heavily grounded by their psychosocial contexts. Clinical implications and future directions for including patient-centered metrics in mainstream practice and research are discussed.

Inhibitors of Protein Methyltransferases and Demethylases

PubMed Central

2017-01-01

Post-translational modifications of histones by protein methyltransferases (PMTs) and histone demethylases (KDMs) play an important role in the regulation of gene expression and transcription and are implicated in cancer and many other diseases. Many of these enzymes also target various nonhistone proteins impacting numerous crucial biological pathways. Given their key biological functions and implications in human diseases, there has been a growing interest in assessing these enzymes as potential therapeutic targets. Consequently, discovering and developing inhibitors of these enzymes has become a very active and fast-growing research area over the past decade. In this review, we cover the discovery, characterization, and biological application of inhibitors of PMTs and KDMs with emphasis on key advancements in the field. We also discuss challenges, opportunities, and future directions in this emerging, exciting research field. PMID:28338320

Metabolic engineering of Saccharomyces cerevisiae for production of fatty acid-derived hydrocarbons.

PubMed

Zhang, Yiming; Nielsen, Jens; Liu, Zihe

2018-06-05

Fatty acid-derived hydrocarbons attract increasing attention as biofuels due to their immiscibility with water, high-energy content, low freezing point, and high compatibility with existing refineries and end-user infrastructures. Yeast Saccharomyces cerevisiae has advantages for production of fatty acid-derived hydrocarbons as its native routes toward fatty acid synthesis involve only a few reactions that allow more efficient conversion of carbon substrates. Here we describe major biosynthetic pathways of fatty acid-derived hydrocarbons in yeast, and summarize key metabolic engineering strategies, including enhancing precursor supply, eliminating competing pathways, and expressing heterologous pathways. With recent advances in yeast production of fatty acid-derived hydrocarbons, our review identifies key research challenges and opportunities for future optimization, and concludes with perspectives and outlooks for further research directions. © 2018 Wiley Periodicals, Inc.

Facilitating comparative effectiveness research in cancer genomics: evaluating stakeholder perceptions of the engagement process.

PubMed

Deverka, Patricia A; Lavallee, Danielle C; Desai, Priyanka J; Armstrong, Joanne; Gorman, Mark; Hole-Curry, Leah; O'Leary, James; Ruffner, B W; Watkins, John; Veenstra, David L; Baker, Laurence H; Unger, Joseph M; Ramsey, Scott D

2012-07-01

The Center for Comparative Effectiveness Research in Cancer Genomics completed a 2-year stakeholder-guided process for the prioritization of genomic tests for comparative effectiveness research studies. We sought to evaluate the effectiveness of engagement procedures in achieving project goals and to identify opportunities for future improvements. The evaluation included an online questionnaire, one-on-one telephone interviews and facilitated discussion. Responses to the online questionnaire were tabulated for descriptive purposes, while transcripts from key informant interviews were analyzed using a directed content analysis approach. A total of 11 out of 13 stakeholders completed both the online questionnaire and interview process, while nine participated in the facilitated discussion. Eighty-nine percent of questionnaire items received overall ratings of agree or strongly agree; 11% of responses were rated as neutral with the exception of a single rating of disagreement with an item regarding the clarity of how stakeholder input was incorporated into project decisions. Recommendations for future improvement included developing standard recruitment practices, role descriptions and processes for improved communication with clinical and comparative effectiveness research investigators. Evaluation of the stakeholder engagement process provided constructive feedback for future improvements and should be routinely conducted to ensure maximal effectiveness of stakeholder involvement.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Heise, J.

The former Homestake gold mine in Lead, South Dakota, has been transformed into a dedicated facility to pursue underground research in rare-process physics, as well as offering research opportunities in other disciplines such as biology, geology and engineering. A key component of the Sanford Underground Research Facility (SURF) is the Davis Campus, which is in operation at the 4850-foot level (4300 m.w.e.) and currently hosts two main physics projects: the LUX dark matter experiment and the MAJORANA DEMONSTRATOR neutrinoless double-beta decay experiment. In addition, two low-background counters currently operate at the Davis Campus in support of current and future experiments. Expansionmore » of the underground laboratory space is underway at the 4850L Ross Campus in order to maintain and enhance low-background assay capabilities as well as to host a unique nuclear astrophysics accelerator facility. Plans to accommodate other future experiments at SURF are also underway and include the next generation of direct-search dark matter experiments and the Fermilab-led international long-baseline neutrino program. Planning to understand the infrastructure developments necessary to accommodate these future projects is well advanced and in some cases have already started. SURF is a dedicated research facility with significant expansion capability.« less

Peer volunteer perspectives following a complex social cognitive intervention: a qualitative investigation.

PubMed

McHugh, J E; Lee, O; Aspell, N; Connolly, L; Lawlor, B A; Brennan, S

2016-09-01

Peer volunteers can be key to delivering effective social cognitive interventions due to increased potential for social modeling. We consulted peer volunteers who had just taken part in an 8-week social and nutritional mealtime intervention with older adults living alone, to seek their evaluation of the intervention. Semi-structured focus groups were used with a total of 21 volunteers (17 female) and two facilitators. Thematic analysis was used to interrogate the data. Six themes (16 sub-themes) are discussed. Peer volunteers described the importance of the socializing aspect of the intervention, of pairing considerations and compatibility in peer interventions, of considering the needs of the participant, of benefits to the volunteers, and of the practical considerations of conducting an intervention. Volunteers also discussed considerations for future research and services for older adults living alone. Volunteers found their involvement in the intervention to be personally beneficial, and revealed some valuable considerations for the researchers to take forward to future research. Results are pertinent to intervention design and could inform future social cognitive and other peer-oriented interventions for older adults living alone.

Coding of DNA samples and data in the pharmaceutical industry: current practices and future directions--perspective of the I-PWG.

PubMed

Franc, M A; Cohen, N; Warner, A W; Shaw, P M; Groenen, P; Snapir, A

2011-04-01

DNA samples collected in clinical trials and stored for future research are valuable to pharmaceutical drug development. Given the perceived higher risk associated with genetic research, industry has implemented complex coding methods for DNA. Following years of experience with these methods and with addressing questions from institutional review boards (IRBs), ethics committees (ECs) and health authorities, the industry has started reexamining the extent of the added value offered by these methods. With the goal of harmonization, the Industry Pharmacogenomics Working Group (I-PWG) conducted a survey to gain an understanding of company practices for DNA coding and to solicit opinions on their effectiveness at protecting privacy. The results of the survey and the limitations of the coding methods are described. The I-PWG recommends dialogue with key stakeholders regarding coding practices such that equal standards are applied to DNA and non-DNA samples. The I-PWG believes that industry standards for privacy protection should provide adequate safeguards for DNA and non-DNA samples/data and suggests a need for more universal standards for samples stored for future research.

Development of Droplet Microfluidics Enabling High-Throughput Single-Cell Analysis.

PubMed

Wen, Na; Zhao, Zhan; Fan, Beiyuan; Chen, Deyong; Men, Dong; Wang, Junbo; Chen, Jian

2016-07-05

This article reviews recent developments in droplet microfluidics enabling high-throughput single-cell analysis. Five key aspects in this field are included in this review: (1) prototype demonstration of single-cell encapsulation in microfluidic droplets; (2) technical improvements of single-cell encapsulation in microfluidic droplets; (3) microfluidic droplets enabling single-cell proteomic analysis; (4) microfluidic droplets enabling single-cell genomic analysis; and (5) integrated microfluidic droplet systems enabling single-cell screening. We examine the advantages and limitations of each technique and discuss future research opportunities by focusing on key performances of throughput, multifunctionality, and absolute quantification.

Montessori education: a review of the evidence base

NASA Astrophysics Data System (ADS)

Marshall, Chloë

2017-10-01

The Montessori educational method has existed for over 100 years, but evaluations of its effectiveness are scarce. This review paper has three aims, namely to (1) identify some key elements of the method, (2) review existing evaluations of Montessori education, and (3) review studies that do not explicitly evaluate Montessori education but which evaluate the key elements identified in (1). The goal of the paper is therefore to provide a review of the evidence base for Montessori education, with the dual aspirations of stimulating future research and helping teachers to better understand whether and why Montessori education might be effective.

Systematic review and overview of health economic evaluation models in obesity prevention and therapy.

PubMed

Schwander, Bjoern; Hiligsmann, Mickaël; Nuijten, Mark; Evers, Silvia

2016-10-01

Given the increasing clinical and economic burden of obesity, it is of major importance to identify cost-effective approaches for obesity management. Areas covered: This study aims to systematically review and compile an overview of published decision models for health economic assessments (HEA) in obesity, in order to summarize and compare their key characteristics as well as to identify, inform and guide future research. Of the 4,293 abstracts identified, 87 papers met our inclusion criteria. A wide range of different methodological approaches have been identified. Of the 87 papers, 69 (79%) applied unique /distinctive modelling approaches. Expert commentary: This wide range of approaches suggests the need to develop recommendations /minimal requirements for model-based HEA of obesity. In order to reach this long-term goal, further research is required. Valuable future research steps would be to investigate the predictiveness, validity and quality of the identified modelling approaches.

Positive versus negative perfectionism in psychopathology: a comment on Slade and Owens's dual process model.

PubMed

Flett, Gordon L; Hewitt, Paul L

2006-07-01

This article reviews the concepts of positive and negative perfectionism and the dual process model of perfectionism outlined by Slade and Owens (1998). The authors acknowledge that the dual process model represents a conceptual advance in the study of perfectionism and that Slade and Owens should be commended for identifying testable hypotheses and future research directions. However, the authors take issue with the notion that there are two types of perfectionism, with one type of perfectionism representing a "normal" or "healthy" form of perfectionism. They suggest that positive perfectionism is motivated, at least in part, by an avoidance orientation and fear of failure, and recent attempts to define and conceptualize positive perfectionism may have blurred the distinction between perfectionism and conscientiousness. Research findings that question the adaptiveness of positive forms of perfectionism are highlighted, and key issues for future research are identified.

Materials Science Experiments Under Microgravity - A Review of History, Facilities, and Future Opportunities

NASA Technical Reports Server (NTRS)

Stenzel, Ch.

2012-01-01

Materials science experiments have been a key issue already since the early days of research under microgravity conditions. A microgravity environment facilitates processing of metallic and semiconductor melts without buoyancy driven convection and sedimentation. Hence, crystal growth of semiconductors, solidification of metallic alloys, and the measurement of thermo-physical parameters are the major applications in the field of materials science making use of these dedicated conditions in space. In the last three decades a large number of successful experiments have been performed, mainly in international collaborations. In parallel, the development of high-performance research facilities and the technological upgrade of diagnostic and stimuli elements have also contributed to providing optimum conditions to perform such experiments. A review of the history of materials science experiments in space focussing on the development of research facilities is given. Furthermore, current opportunities to perform such experiments onboard ISS are described and potential future options are outlined.

Special report: workshop on 4D-treatment planning in actively scanned particle therapy--recommendations, technical challenges, and future research directions.

PubMed

Knopf, Antje; Bert, Christoph; Heath, Emily; Nill, Simeon; Kraus, Kim; Richter, Daniel; Hug, Eugen; Pedroni, Eros; Safai, Sairos; Albertini, Francesca; Zenklusen, Silvan; Boye, Dirk; Söhn, Matthias; Soukup, Martin; Sobotta, Benjamin; Lomax, Antony

2010-09-01

This article reports on a 4D-treatment planning workshop (4DTPW), held on 7-8 December 2009 at the Paul Scherrer Institut (PSI) in Villigen, Switzerland. The participants were all members of institutions actively involved in particle therapy delivery and research. The purpose of the 4DTPW was to discuss current approaches, challenges, and future research directions in 4D-treatment planning in the context of actively scanned particle radiotherapy. Key aspects were addressed in plenary sessions, in which leaders of the field summarized the state-of-the-art. Each plenary session was followed by an extensive discussion. As a result, this article presents a summary of recommendations for the treatment of mobile targets (intrafractional changes) with actively scanned particles and a list of requirements to elaborate and apply these guidelines clinically.

Review: An urgent need for research on factors impacting adherence to and retention in care among HIV-positive youth and adolescents from key populations

PubMed Central

Lall, Priya; Lim, Sin How; Khairuddin, Norliana; Kamarulzaman, Adeeba

2015-01-01

Introduction The 50% increase in HIV-related deaths in youth and adolescents (aged 10–24) from 2005 to 2012 highlights the need to improve HIV treatment and care in this population, including treatment adherence and retention. Youth and adolescents from key populations or young key populations (YKP) in particular are highly stigmatized and may face additional barrier(s) in adhering to HIV treatment and services. We reviewed the current knowledge on treatment adherence and retention in HIV care among YKP to identify gaps in the literature and suggest future directions to improve HIV care for YKP. Methods We conducted a comprehensive literature search for YKP and their adherence to antiretroviral therapy (ART) and retention in HIV care on PsycInfo (Ovid), PubMed and Google Scholar using combinations of the keywords HIV/AIDS, ART, adolescents, young adults, adherence (or compliance), retention, men who have sex with men, transgender, injection drug users, people who inject drugs and prisoners. We included empirical studies on key populations defined by WHO; included the terms youth and adolescents and/or aged between 10 and 24; examined adherence to or retention in HIV care; and published in English-language journals. All articles were coded using NVivo. Results and discussion The systematic search yielded 10 articles on YKP and 16 articles on behaviourally infected youth and adolescents from 1999 to 2014. We found no studies reporting on youth and adolescents identified as sex workers, transgender people and prisoners. From existing literature, adherence to ART was reported to be influenced by age, access to healthcare, the burden of multiple vulnerabilities, policy involving risk behaviours and mental health. A combination of two or more of these factors negatively impacted adherence to ART among YKP. Collectively, these studies demonstrated that future programmes need to be tailored specifically to YKP to ensure adherence. Conclusions There is an urgent need for more systematic research in YKP. Current limited evidence suggests that healthcare delivery should be tailored to the unique needs of YKP. Thus, research on YKP could be used to inform future interventions to improve access to treatment and management of co-morbidities related to HIV, to ease the transition from paediatric to adult care and to increase uptake of secondary prevention methods. PMID:25724503

Addressing weight bias and discrimination: moving beyond raising awareness to creating change.

PubMed

Ramos Salas, X; Alberga, A S; Cameron, E; Estey, L; Forhan, M; Kirk, S F L; Russell-Mayhew, S; Sharma, A M

2017-11-01

Weight discrimination is the unjust treatment of individuals because of their weight. There have been very few interventions to address weight discrimination, due in part to the lack of consensus on key messages and strategies. The objective of the third Canadian Weight Bias Summit was to review current evidence and move towards consensus on key weight bias and obesity discrimination reduction messages and strategies. Using a modified brokered dialogue approach, participants, including researchers, health professionals, policy makers and people living with obesity, reviewed the evidence and moved towards consensus on key messages and strategies for future interventions. Participants agreed to these key messages: (1) Weight bias and obesity discrimination should not be tolerated in education, health care and public policy sectors; (2) obesity should be recognized and treated as a chronic disease in health care and policy sectors; and (3) in the education sector, weight and health need to be decoupled. Consensus on future strategies included (1) creating resources to support policy makers, (2) using personal narratives from people living with obesity to engage audiences and communicate anti-discrimination messages and (3) developing a better clinical definition for obesity. Messages and strategies should be implemented and evaluated using consistent theoretical frameworks and methodologies. © 2017 World Obesity Federation.

Perovskite Solar Cells and Devices at EPFL Valais Wallis.

PubMed

Nazeeruddin, Mohammad Khaja

2016-09-22

Stability required! Perovskite solar cells have emerged as one of the most exciting fields of research, owing to their impressive rise in power conversion efficiency surpassing 22% in six short years of research. Current research is focused on ways to improve stability of perovskite-based devices, a key characteristic required to bring this technology from the lab into the market. In this Editorial, guest editor Prof. Mohammad Khaja Nazeeruddin describes the context of this Special Issue, and summarizes the work being performed in his research group toward this low-cost near-future photovoltaic technology. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

ICI-RS 2015-Is a better understanding of sleep the key in managing nocturia?

PubMed

Denys, Marie-Astrid; Cherian, Jerald; Rahnama'i, Mohammad S; O'Connell, Kathleen A; Singer, Jonathan; Wein, Alan J; Dhondt, Karlien; Everaert, Karel; Weiss, Jeffrey P

2016-09-21

Nocturia, or waking up at night to void, is a highly prevalent and bothersome lower urinary tract symptom. However, the applied treatment modalities do not improve symptoms in about half of the patients. The aim of this report is to generate new ideas for future nocturia research, with special emphasis on the role of sleep physiology and sleep disorders. The following is a report of the presentations and subsequent discussion of the Nocturia Think Tank session at the annual meeting of the International Consultation on Incontinence Research Society (ICI-RS), which took place in September 2015 in Bristol. General information about the organization of the ICI-RS meeting can be found on the website "www.ici-rs.org." An overview of challenges within the existing evidence, future research ideas, and results of research with regard to nocturia and sleep were presented. In order to optimize the management of nocturia and nocturnal polyuria (NP), future research has to focus on the development of unambiguous terminology regarding nocturia and NP, the role of renal function profiles and simplified frequency volume charts as guidance of individualized therapy and the role of sleep disorders such as periodic limb movements during sleep and habitual voiding as a response to awakening. Neurourol. Urodynam. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

Oral manifestations of HIV/AIDS in Asia: Systematic review and future research guidelines.

PubMed

Sharma, Gaurav; Oberoi, Sukhvinder-Singh; Vohra, Puneeta; Nagpal, Archna

2015-07-01

The authors have conducted a systematic review of oral manifestations of HIV from studies conducted in Asia to establish the characteristics and prevalence of individual oral manifestations in Asia, and to assess the direction of future research studies on oral manifestations of HIV in Asia. The electronic retrieval systems and databases searched for relevant articles were PubMed [MEDLINE], EBSCO, and EMBASE. The search was for limited articles published in English or with an English abstract and articles published during the period January 1995 to August 2014. The authors reached a final overall sample of 39 studies that were conducted in Asia. The median population size among all studies was 312.7 patients. Oral candidiasis [OC] was the most common oral manifestation [37.7%] in studies conducted in Asia. The overall prevalence of oral hairy leukoplakia and melanotic hyperpigmentation was computed to be 10.1% and 22.8% respectively. Thailand and India are primarily countries with maximum research on oral manifestations. The research on oral manifestations of HIV in Asia has to upgrade to more interventional and therapeutic studies rather than the contemporary cross- sectional epidemiological descriptive studies. The authors have given suggestions and future directions for the implementation of clinical research of oral manifestations in HIV patients. Key words:Oral manifestations, HIV/AIDS, Asia, Systematic review.

Towards a Pedagogy of Philoxenia (Hospitality): Negotiating Policy Priorities for Immigrant Students in Greek Public Schools

ERIC Educational Resources Information Center

Macris, Vicki

2012-01-01

This paper reflects and supports the focus of my doctoral research that aims to identify, underscore and examine some of the key challenges and policy barriers that are shaped or hindered by socio-political, ethno-cultural and economic factors that subsequently impede immigrant students' transition and future academic and social success in their…

Enhancing the Professional Mindset of Future Sales Professionals: Key Insights from a Master in Sales Transformation

ERIC Educational Resources Information Center

Marcos-Cuevas, Javier; Critten, Peter; Squire, Phil; Speakman, James I. F.

2014-01-01

Sales education has grown in importance, particularly throughout the last decade, with an increasing number of university sales centers offering programs to prepare new generations of sales professionals. In this article, we describe how work-based learning, action research, and reflective practice used in a sales master program can be used in…

Revitalizing Traditional Information Literacy Instruction: Exploring Games in Academic Libraries

ERIC Educational Resources Information Center

Margino, Megan

2013-01-01

The Future Voices in Public Services column is a forum for students in graduate library and information science programs to discuss key issues they see in academic library public services, to envision what they feel librarians in public service have to offer to academia, to tell of their visions for the profession, or to tell of research that is…

Creating Sustainable Relationships Using the Strengths, Opportunities, Aspirations and Results Framework, Trust, and Environmentalism: A Research-Based Case Study

ERIC Educational Resources Information Center

Sprangel, Joseph; Stavros, Jacqueline; Cole, Matthew

2011-01-01

New forms of organization development are moving from a classical diagnostic perspective to a dialogic perspective. This move includes a focus on exploring positive states of organizing, shared aspirations, and the design of preferred futures as key outcomes of a strategic change process. Training and development that applies the elements of the…

Lest the World Forget: Sri Lanka's Educational Needs after the 2004 Tsunami

ERIC Educational Resources Information Center

Cashman, Timothy G.; Asing-Cashman, Joyce G.

2006-01-01

This qualitative study strives to provide a greater understanding of the past, current, and future state of education in Sri Lanka after the 2004 tsunami. The researchers' key objectives are to provide additional insight to educators of the far-reaching impact of the tsunami via a website they created. Rather than concentrate on the same sort of…

School Leadership for the Future: Heroic or Distributed? Translating International Discourses in Norwegian Policy Documents

ERIC Educational Resources Information Center

Abrahamsen, Hedvig; Aas, Marit

2016-01-01

School leadership as a key for school reforms has become a dominant theme in education, as demonstrated by a growing body of research during the last 15 years. Still, little attention has been paid to how changing international discourses on school leadership are translated into national public policy documents during the last decade. As such,…

Clinical ethics revisited

PubMed Central

Singer, Peter A; Pellegrino, Edmund D; Siegler, Mark

2001-01-01

A decade ago, we reviewed the field of clinical ethics; assessed its progress in research, education, and ethics committees and consultation; and made predictions about the future of the field. In this article, we revisit clinical ethics to examine our earlier observations, highlight key developments, and discuss remaining challenges for clinical ethics, including the need to develop a global perspective on clinical ethics problems. PMID:11346456

Social Media in Academic Libraries: Engaging in 140 Characters or Less

ERIC Educational Resources Information Center

Levesque, Lisa

2016-01-01

The Future Voices in Public Services column is a forum for students in graduate library and information science programs to discuss key issues they see in academic library public services, to envision what they feel librarians in public service have to offer to academia, to tell of their visions for the profession, or to tell of research that is…

Documenting 15 Years (2000-2015) of SOPHE Achievements: Recent Developments and Future Directions

ERIC Educational Resources Information Center

Alber, Julia M.; Bernhardt, Jay M.; Stellefson, Michael; Paige, Samantha R.

2017-01-01

For over six decades, the Society for Public Health Education (SOPHE) has been a leading professional organization for the field of health education (HE). This historical research extends the work of Cissell and Bloom by investigating the recent history of SOPHE. The aims of this historical study were to (1) identify key SOPHE and HE events from…

Best Practice Irrigation Management and Extension in Peri-Urban Landscapes--Experiences and Insights from the Hawkesbury-Nepean Catchment, Australia

ERIC Educational Resources Information Center

Maheshwari, B. L.; Plunkett, M.

2015-01-01

Purpose: The aim of this article to examine key irrigation management issues and their implications for future research and extension developments. Design/Methodology/Approach: Peri-urban landscapes are important as they supply fresh fruit, vegetables, turf, ornamental plants and other farm products to the cities. In this study, the…

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shiltsev, Vladimir

The 2014 P5 report indicated the accelerator-based neutrino and rare decay physics research as a centerpiece of the US domestic HEP program. Operation, upgrade and development of the accelerators for the near-term and longer-term particle physics program at the Intensity Frontier face formidable challenges. Here we discuss key elements of the accelerator physics and technology R&D program toward future multi-MW proton accelerators.

Professionals' Perceptions about the Use of Research in Educational Practice

ERIC Educational Resources Information Center

Ion, Georgeta; Iucu, Romita

2014-01-01

The Lisbon strategy adopted in 2000 by the European Council considers knowledge to be the key element in ensuring future European Union economic growth and in promoting social cohesion. With this aim in mind, a solid base is needed so that knowledge can not only be produced and but also be used to good effect. For any undertaking based on the…

100 years of Drosophila research and its impact on vertebrate neuroscience: a history lesson for the future.

PubMed

Bellen, Hugo J; Tong, Chao; Tsuda, Hiroshi

2010-07-01

Discoveries in fruit flies have greatly contributed to our understanding of neuroscience. The use of an unparalleled wealth of tools, many of which originated between 1910–1960, has enabled milestone discoveries in nervous system development and function. Such findings have triggered and guided many research efforts in vertebrate neuroscience. After 100 years, fruit flies continue to be the choice model system for many neuroscientists. The combinational use of powerful research tools will ensure that this model organism will continue to lead to key discoveries that will impact vertebrate neuroscience.

HIV vaccine development: past, present and future.

PubMed

Robb, Merlin L

2010-12-01

The search for an HIV vaccine began following the discovery of the virus more than 25 years ago. Despite important progress, an effective vaccine remains an elusive goal that will likely require many more years of R&D to achieve. Following recent advances in research, however, there has been increased optimism that a prophylactic HIV vaccine is feasible. A consensus is forming among researchers to support a larger role for proof-of-concept efficacy clinical trials, conducted in parallel with invigorated basic research efforts and testing in animal models, to accelerate the discovery of key principles that will guide rational vaccine development.

Multilayered Functional Insulation System (MFIS) for AC Power Transmission in High Voltage Hybrid Electrical Propulsion

NASA Technical Reports Server (NTRS)

Lizcano, Maricela

2017-01-01

High voltage hybrid electric propulsion systems are now pushing new technology development efforts for air transportation. A key challenge in hybrid electric aircraft is safe high voltage distribution and transmission of megawatts of power (>20 MW). For the past two years, a multidisciplinary materials research team at NASA Glenn Research Center has investigated the feasibility of distributing high voltage power on future hybrid electric aircraft. This presentation describes the team's approach to addressing this challenge, significant technical findings, and next steps in GRC's materials research effort for MW power distribution on aircraft.

100 years of Drosophila research and its impact on vertebrate neuroscience: a history lesson for the future

PubMed Central

Bellen, Hugo J; Tong, Chao; Tsuda, Hiroshi

2014-01-01

Discoveries in fruit flies have greatly contributed to our understanding of neuroscience. The use of an unparalleled wealth of tools, many of which originated between 1910–1960, has enabled milestone discoveries in nervous system development and function. Such findings have triggered and guided many research efforts in vertebrate neuroscience. After 100 years, fruit flies continue to be the choice model system for many neuroscientists. The combinational use of powerful research tools will ensure that this model organism will continue to lead to key discoveries that will impact vertebrate neuroscience. PMID:20383202

Materials Research With Neutrons at NIST

PubMed Central

Cappelletti, R. L.; Glinka, C. J.; Krueger, S.; Lindstrom, R. A.; Lynn, J. W.; Prask, H. J.; Prince, E.; Rush, J. J.; Rowe, J. M.; Satija, S. K.; Toby, B. H.; Tsai, A.; Udovic, T. J.

2001-01-01

The NIST Materials Science and Engineering Laboratory works with industry, standards bodies, universities, and other government laboratories to improve the nation’s measurements and standards infrastructure for materials. An increasingly important component of this effort is carried out at the NIST Center for Neutron Research (NCNR), at present the most productive center of its kind in the United States. This article gives a brief historical account of the growth and activities of the Center with examples of its work in major materials research areas and describes the key role the Center can expect to play in future developments. PMID:27500021

Accounting for Sitting and Moving: An Analysis of Sedentary Behavior in Mass Media Campaigns.

PubMed

Knox, Emily; Biddle, Stuart; Esliger, Dale W; Piggin, Joe; Sherar, Lauren

2015-09-01

Mass media campaigns are an important tool for promoting health-related physical activity. The relevance of sedentary behavior to public health has propelled it to feature prominently in health campaigns across the world. This study explored the use of messages regarding sedentary behavior in health campaigns within the context of current debates surrounding the association between sedentary behavior and health, and messaging strategies to promote moderate-to-vigorous physical activity (MVPA). A web-based search of major campaigns in the United Kingdom, United States, Canada, and Australia was performed to identify the main campaign from each country. A directed content analysis was then conducted to analyze the inclusion of messages regarding sedentary behavior in health campaigns and to elucidate key themes. Important areas for future research were illustrated. Four key themes from the campaigns emerged: clinging to sedentary behavior guidelines, advocating reducing sedentary behavior as a first step on the activity continuum and the importance of light activity, confusing the promotion of MVPA, and the demonization of sedentary behavior. Strategies for managing sedentary behavior as an additional complicating factor in health promotion are urgently required. Lessons learned from previous health communication campaigns should stimulate research to inform future messaging strategies.

CO2 studies remain key to understanding a future world.

PubMed

Becklin, Katie M; Walker, S Michael; Way, Danielle A; Ward, Joy K

2017-04-01

Contents 34 I. 34 II. 36 III. 37 IV. 37 V. 38 38 References 38 SUMMARY: Characterizing plant responses to past, present and future changes in atmospheric carbon dioxide concentration ([CO 2 ]) is critical for understanding and predicting the consequences of global change over evolutionary and ecological timescales. Previous CO 2 studies have provided great insights into the effects of rising [CO 2 ] on leaf-level gas exchange, carbohydrate dynamics and plant growth. However, scaling CO 2 effects across biological levels, especially in field settings, has proved challenging. Moreover, many questions remain about the fundamental molecular mechanisms driving plant responses to [CO 2 ] and other global change factors. Here we discuss three examples of topics in which significant questions in CO 2 research remain unresolved: (1) mechanisms of CO 2 effects on plant developmental transitions; (2) implications of rising [CO 2 ] for integrated plant-water dynamics and drought tolerance; and (3) CO 2 effects on symbiotic interactions and eco-evolutionary feedbacks. Addressing these and other key questions in CO 2 research will require collaborations across scientific disciplines and new approaches that link molecular mechanisms to complex physiological and ecological interactions across spatiotemporal scales. © 2016 The Authors. New Phytologist © 2016 New Phytologist Trust.

Teamwork situated in multiteam systems: Key lessons learned and future opportunities.

PubMed

Shuffler, Marissa L; Carter, Dorothy R

2018-01-01

Many important contexts requiring teamwork, including health care, space exploration, national defense, and scientific discovery, present important challenges that cannot be addressed by a single team working independently. Instead, the complex goals these contexts present often require effectively coordinated efforts of multiple specialized teams working together as a multiteam system (MTS). For almost 2 decades, researchers have endeavored to understand the novelties and nuances for teamwork and collaboration that ensue when teams operate together as "component teams" in these interdependent systems. In this special issue on the settings of teamwork, we aim to synthesize what is known thus far regarding teamwork situated in MTS contexts and offer new directions and considerations for developing, maintaining, and sustaining effective collaboration in MTSs. Our review of extant research on MTSs reveals 7 key lessons learned regarding teamwork situated in MTSs, but also reveals that much is left to learn about the science and practice of ensuring effective multiteam functioning. We elaborate these lessons and delineate 4 major opportunities for advancing the science of MTSs as a critical embedding context for collaboration and teamwork, now and in the future. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

White water: Fifty years of snow research in WRR and the outlook for the future

NASA Astrophysics Data System (ADS)

Sturm, Matthew

2015-07-01

Over the past 50 years, 239 papers related to snow have been published in Water Resources Research (WRR). Seminal papers on virtually every facet of snow physics and snow water resources have appeared in the journal. These include papers on drifting snow, the snow surface energy balance, the effect of grain size on albedo, chemical elution, water movement through snow, and canopy interception. In particular, papers in WRR have explored the distribution of snow across different landscapes, providing data, process knowledge, and the basis for virtually all of the distributed snow models in use today. In this paper, I review these key contributions and provide some personal thoughts on what is likely to be the focus and nature of papers published in the next few decades, a period that is likely to see an increasing ability to map snow cover in detail, which should serve as a basis for the further development and improvement of snow models. It will also be an uncertain future, with profound changes in snow climatology predicted. I expect WRR will continue to play a key role in documenting and understanding these important cryospheric changes.

Directions for social research to underpin improved groundwater management

NASA Astrophysics Data System (ADS)

Mitchell, Michael; Curtis, Allan; Sharp, Emily; Mendham, Emily

2012-07-01

SummaryImprovements in groundwater management require strategies to change human behaviour, yet there has been limited social research in the broad arena of groundwater management. This paper provides a critical review of the small but expanding literature on that topic to identify future directions for social researchers. Comprehensive search methods identified almost three hundred potentially relevant publications, which were sorted thematically and assessed in terms of their theoretical underpinning and the evidence used to support key findings. This process enabled the authors to identify a small number of high quality publications and to identify future research opportunities. The latter includes analysing how concepts of risk and sustainable yield are constructed differently by stakeholders, especially related to divisive issues concerning coal seam gas developments and reforms that reduce irrigation allocations; how governance arrangements can be improved to achieve more effective collaborative management of groundwater, especially if managed aquifer recharge is to be more widely implemented in rural agricultural contexts; and the role that trust and social norms can play in changing groundwater use practices.

Taking stock of two relational aspects of organizational life: Tracing the history and shaping the future of socialization and mentoring research.

PubMed

Allen, Tammy D; Eby, Lillian T; Chao, Georgia T; Bauer, Talya N

2017-03-01

As part of the centennial celebration for the Journal of Applied Psychology , this article reviews the literature on organizational socialization and mentoring. Our review includes a comparison of organizational socialization and mentoring as processes for employee adjustment and development, the historical context that fueled the emergence of these two areas of study, and a chronological mapping of key foundations, trends, themes that emerged across time, and major milestones. Along the way, a special emphasis is placed on research published in the Journal of Applied Psychology and high impact work is highlighted. We conclude with a discussion of five areas for future research. Specifically, we outline ideas for bridging the socialization and mentoring literatures, better understanding and capturing dynamic processes across time, the development of multilevel theories and models, addressing causality, and considering the implications for organizational socialization and mentoring research based on how technology is changing the way we work. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

EURADOS strategic research agenda: vision for dosimetry of ionising radiation.

PubMed

Rühm, W; Fantuzzi, E; Harrison, R; Schuhmacher, H; Vanhavere, F; Alves, J; Bottollier Depois, J F; Fattibene, P; Knežević, Ž; Lopez, M A; Mayer, S; Miljanić, S; Neumaier, S; Olko, P; Stadtmann, H; Tanner, R; Woda, C

2016-02-01

Since autumn 2012, the European Radiation Dosimetry Group (EURADOS) has been developing its Strategic Research Agenda (SRA), which is intended to contribute to the identification of future research needs in radiation dosimetry in Europe. The present article summarises-based on input from EURADOS Working Groups (WGs) and Voting Members-five visions in dosimetry and defines key issues in dosimetry research that are considered important for the next decades. The five visions include scientific developments required towards (a) updated fundamental dose concepts and quantities, (b) improved radiation risk estimates deduced from epidemiological cohorts, (c) efficient dose assessment for radiological emergencies, (d) integrated personalised dosimetry in medical applications and (e) improved radiation protection of workers and the public. The SRA of EURADOS will be used as a guideline for future activities of the EURADOS WGs. A detailed version of the SRA can be downloaded as a EURADOS report from the EURADOS website (www.eurados.org). © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Updates and future horizons on the understanding, diagnosis, and treatment of Sturge-Weber syndrome brain involvement.

PubMed

Lo, Warren; Marchuk, Douglas A; Ball, Karen L; Juhász, Csaba; Jordan, Lori C; Ewen, Joshua B; Comi, Anne

2012-03-01

To review recent developments in the understanding, diagnosis, and treatment of Sturge-Weber syndrome (SWS). Members of the Brain Vascular Malformation Consortium Sturge-Weber Syndrome National Workgroup contributed their expertise to review the literature and present promising directions for research. The increasing number of reports dealing with SWS over the last decade reflects progress in the diagnosis and understanding of the neurological involvement. The proliferation of centers and advocacy groups to care for patients with SWS and to stimulate research has aided the development of new insights into the clinical manifestations and the pathophysiology of neurological progression, and the development of novel hypotheses to direct future research. Many key questions remain, but the tools and networks to answer them are being developed. This review summarizes important new knowledge and presents new research directions that are likely to provide further insights, earlier diagnosis, improved treatments, and possibly, prevention of this syndrome. © The Authors. Developmental Medicine & Child Neurology © 2011 Mac Keith Press.

Blueprint for Action: Visioning Summit on the Future of the Workforce in Pediatrics.

PubMed

Sectish, Theodore C; Hay, William W; Mahan, John D; Mendoza, Fernando S; Spector, Nancy D; Stanton, Bonita; Szilagyi, Peter G; Turner, Teri L; Walker, Leslie R; Slaw, Kenneth

2015-07-01

The Federation of Pediatric Organizations engaged members of the pediatric community in an 18-month process to envision the future of the workforce in pediatrics, culminating in a Visioning Summit on the Future of the Workforce in Pediatrics. This article documents the planning process and methods used. Four working groups were based on the 4 domains that are likely to affect the future workforce: Child Health Research and Training, Diversity and Inclusion, Gender and Generations, and Pediatric Training Along the Continuum. These groups identified the issues and trends and prioritized their recommendations. Before the summit, 5 key megatrends cutting across all domains were identified:1. Aligning Education to the Emerging Health Needs of Children and Families 2. Promoting Future Support for Research Training and for Child Health Research 3. Striving Toward Mastery Within the Profession 4. Aligning and Optimizing Pediatric Practice in a Changing Health Care Delivery System 5. Taking Advantage of the Changing Demographics and Expertise of the Pediatric Workforce At the Visioning Summit, we assembled members of each of the working groups, the Federation of Pediatric Organizations Board of Directors, and several invited guests to discuss the 5 megatrends and develop the vision, solutions, and actions for each megatrend. Based on this discussion, we offer 10 recommendations for the field of pediatrics and its leading organizations to consider taking action. Copyright © 2015 by the American Academy of Pediatrics.

The yin and yang of yeast: biodiversity research and systems biology as complementary forces driving innovation in biotechnology.

PubMed

Roberts, Ian N; Oliver, Stephen G

2011-03-01

The aim of this article is to review how yeast has contributed to contemporary biotechnology and to seek underlying principles relevant to its future exploitation for human benefit. Recent advances in systems biology combined with new knowledge of genome diversity promise to make yeast the eukaryotic workhorse of choice for production of everything from probiotics and pharmaceuticals to fuels and chemicals. The ability to engineer new capabilities through introduction of controlled diversity based on a complete understanding of genome complexity and metabolic flux is key. Here, we briefly summarise the history that has led to these apparently simple organisms being employed in such a broad range of commercial applications. Subsequently, we discuss the likely consequences of current yeast research for the future of biotechnological innovation.

Software architecture and engineering for patient records: current and future.

PubMed

Weng, Chunhua; Levine, Betty A; Mun, Seong K

2009-05-01

During the "The National Forum on the Future of the Defense Health Information System," a track focusing on "Systems Architecture and Software Engineering" included eight presenters. These presenters identified three key areas of interest in this field, which include the need for open enterprise architecture and a federated database design, net centrality based on service-oriented architecture, and the need for focus on software usability and reusability. The eight panelists provided recommendations related to the suitability of service-oriented architecture and the enabling technologies of grid computing and Web 2.0 for building health services research centers and federated data warehouses to facilitate large-scale collaborative health care and research. Finally, they discussed the need to leverage industry best practices for software engineering to facilitate rapid software development, testing, and deployment.

Preparing Future Faculty and Professionals for Public Health Careers

PubMed Central

Hrapczynski, Katie M.; Clark, Jane E.

2015-01-01

Recent years have brought rapid growth in schools of public health and an increasing demand for public health practitioners. These trends highlight the need for innovative approaches to prepare doctoral graduates for academic and high-level practice positions. The University of Maryland’s School of Public Health developed a “Preparing Future Faculty and Professionals” program to enrich the graduate education and professional development of its doctoral students. We describe the program’s key elements, including foundational seminars to enhance students’ knowledge and skills related to teaching, research, and service; activities designed to foster career exploration and increase competitiveness in the job market; and independent, faculty-mentored teaching and research experiences. We present a model for replicating the program and share student outcomes of participation. PMID:25706007

Future HIV Mentoring Programs to Enhance Diversity.

PubMed

Stoff, David M; Cargill, Victoria A

2016-09-01

This paper proposes a general template to guide future mentoring program development addressing: (i) considerations to ensure an adequate research workforce; (ii) key guidelines and principles of mentoring; and (iii) use of a logic model to develop program milestones, outcomes and evaluation. We focus on these areas to guide and inform the most effective mentoring program components, which we find to be more helpful than identifying specific features and ingredients. Although the focus is on the development of a new generation of investigators from diverse backgrounds, this template may also apply to mentoring programs for other investigators and for disciplines beyond HIV.

Childhood Hemorrhagic Stroke: An Important but Understudied Problem

PubMed Central

Lo, Warren

2013-01-01

Hemorrhagic stroke in children occurs more frequently than is commonly appreciated. There are important differences in the factors associated with hemorrhagic stroke in children when compared with adults. These differences likely play a role in the different outcomes, which tend to worsen with age. In this review, we describe the estimated frequency, clinical presentation, acute management of hemorrhagic stroke, and an overview of rehabilitation techniques. We identify key topics for future basic and clinical research. Findings from future studies will help improve our ability to optimize treatment for and long-term rehabilitation of these patients. PMID:21633104

Aeropropulsion 1987. Session 6: High-Speed Propulsion Technology

NASA Technical Reports Server (NTRS)

1987-01-01

NASA is conducting aeronautical research over a broad range of Mach numbers. In addition to the advanced CTOL propulsion research described in a separate session, the Lewis Research Center has intensified its efforts towards propulsion technology for selected high-speed flight applications. In a companion program, the Langley Research Center has also accomplished excellent research in Supersonic Combustion Ramjet (SCRAM) propulsion. What is presented in this session is an unclassified review of some of the propulsion research results that are applicable for supersonic to hypersonic vehicles. Not only is a review provided for several key work areas, it also presents a viewpoint on future research directions by calling attention to cycles, components, and facilities involved in this rapidly expanding field of work.

Key Challenges and New Trends in Battery Research (2011 EFRC Forum)

ScienceCinema

Tarascon, Jean Marie

2018-02-13

Jean-Marie Tarascon, Professor at the University de Picardie Jules Verne, France, was the fourth speaker in the May 26, 2011 EFRC Forum session, "Global Perspectives on Frontiers in Energy Research." In his presentation, Professor Tarascon recounted European basic research activates in electrical energy storage. The 2011 EFRC Summit and Forum brought together the EFRC community and science and policy leaders from universities, national laboratories, industry and government to discuss "Science for our Nation's Energy Future." In August 2009, the Office of Science established 46 Energy Frontier Research Centers. The EFRCs are collaborative research efforts intended to accelerate high-risk, high-reward fundamental research, the scientific basis for transformative energy technologies of the future. These Centers involve universities, national laboratories, nonprofit organizations, and for-profit firms, singly or in partnerships, selected by scientific peer review. They are funded at $2 to $5 million per year for a total planned DOE commitment of $777 million over the initial five-year award period, pending Congressional appropriations. These integrated, multi-investigator Centers are conducting fundamental research focusing on one or more of several “grand challenges” and use-inspired “basic research needs” recently identified in major strategic planning efforts by the scientific community. The purpose of the EFRCs is to integrate the talents and expertise of leading scientists in a setting designed to accelerate research that transforms the future of energy and the environment.

High Efficiency Centrifugal Compressor for Rotorcraft Applications

NASA Technical Reports Server (NTRS)

Medic, Gorazd; Sharma, Om P.; Jongwook, Joo; Hardin, Larry W.; McCormick, Duane C.; Cousins, William T.; Lurie, Elizabeth A.; Shabbir, Aamir; Holley, Brian M.; Van Slooten, Paul R.

2017-01-01

A centrifugal compressor research effort conducted by United Technologies Research Center under NASA Research Announcement NNC08CB03C is documented. The objectives were to identify key technical barriers to advancing the aerodynamic performance of high-efficiency, high work factor, compact centrifugal compressor aft-stages for turboshaft engines; to acquire measurements needed to overcome the technical barriers and inform future designs; to design, fabricate, and test a new research compressor in which to acquire the requisite flow field data. A new High-Efficiency Centrifugal Compressor stage -- splittered impeller, splittered diffuser, 90 degree bend, and exit guide vanes -- with aerodynamically aggressive performance and configuration (compactness) goals were designed, fabricated, and subquently tested at the NASA Glenn Research Center.

The first Research Consensus Summit of the Society for Simulation in Healthcare: conduction and a synthesis of the results.

PubMed

Dieckmann, Peter; Phero, James C; Issenberg, S Barry; Kardong-Edgren, Suzie; Ostergaard, Doris; Ringsted, Charlotte

2011-08-01

In this article, we describe the preparation and execution of the first Research Consensus Summit (Summit) of the Society for Simulation in Healthcare (SSH) held in January 2011 in New Orleans, Louisiana. The goals of the Summit were to provide guidance for better simulation-related research, to broaden the scope of topics investigated, and to highlight the importance of simulation-related research. An international Core Group (the authors of this article) worked with the SSH Research Committee to identify 10 topic areas relevant for future research that would be examined by the 10 Topic Groups composed of Topic Chairs and Topic Group Members. Each Topic Group prepared a monograph and slide presentation on their topic which was presented at the 2-day Summit. The audience provided feedback on each presentation. Based on this feedback, the Topic Groups revised their presentations and monographs for publication in this supplement to Simulation in Healthcare. The Core Group has synthesized an overview of the key Summit themes in this article. In some groups, the agreement was that there is currently no consensus about the state of the science in certain topic aspects. Some key themes emerged from the Topic Groups. The conceptual and theoretical bases of simulation-related research, as well as the methods used and their methodological foundations, need to be more explicitly described in future publications. Although no single method is inherently better, the mix of research methods chosen should match the goal of each study. The impact of simulation, whether direct or indirect, needs to be assessed across different levels of training, and larger, more complex contexts need to be taken into account. When interpreting simulation-related research, the ecological validity of the results needs to be taken into consideration. The scope of simulation-related research can be widened from having simulation as the focus of research (research about simulation), to using simulation to investigate other research questions (research with simulation). Simulation-related research can benefit from an improved understanding of structural differences and similarities with other domains. The development of simulation equipment and concepts will benefit from applying known and available science-based design frameworks. Overall, the context of simulation-related research needs to be better understood. The progress of research depends on building overarching and sustainable research programs that relate individual studies with each other. The Summit was successful in taking a snapshot of the state of the science. Future summits might explore these topics further, monitor progress, and address new topics.

Developing, implementing and disseminating a core outcome set for neonatal medicine.

PubMed

Webbe, James; Brunton, Ginny; Ali, Shohaib; Duffy, James Mn; Modi, Neena; Gale, Chris

2017-01-01

In high resource settings, 1 in 10 newborn babies require admission to a neonatal unit. Research evaluating neonatal care involves recording and reporting many different outcomes and outcome measures. Such variation limits the usefulness of research as studies cannot be compared or combined. To address these limitations, we aim to develop, disseminate and implement a core outcome set for neonatal medicine. A steering group that includes parents and former patients, healthcare professionals and researchers has been formed to guide the development of the core outcome set. We will review neonatal trials systematically to identify previously reported outcomes. Additionally, we will specifically identify outcomes of importance to parents, former patients and healthcare professionals through a systematic review of qualitative studies. Outcomes identified will be entered into an international, multi-perspective eDelphi survey. All key stakeholders will be invited to participate. The Delphi method will encourage individual and group stakeholder consensus to identify a core outcome set. The core outcome set will be mapped to existing, routinely recorded data where these exist. Use of a core set will ensure outcomes of importance to key stakeholders, including former patients and parents, are recorded and reported in a standard fashion in future research. Embedding the core outcome set within future clinical studies will extend the usefulness of research to inform practice, enhance patient care and ultimately improve outcomes. Using routinely recorded electronic data will facilitate implementation with minimal addition burden. Core Outcome Measures in Effectiveness Trials (COMET) database: 842 (www.comet-initiative.org/studies/details/842).

Quantum key distribution in a multi-user network at gigahertz clock rates

NASA Astrophysics Data System (ADS)

Fernandez, Veronica; Gordon, Karen J.; Collins, Robert J.; Townsend, Paul D.; Cova, Sergio D.; Rech, Ivan; Buller, Gerald S.

2005-07-01

In recent years quantum information research has lead to the discovery of a number of remarkable new paradigms for information processing and communication. These developments include quantum cryptography schemes that offer unconditionally secure information transport guaranteed by quantum-mechanical laws. Such potentially disruptive security technologies could be of high strategic and economic value in the future. Two major issues confronting researchers in this field are the transmission range (typically <100km) and the key exchange rate, which can be as low as a few bits per second at long optical fiber distances. This paper describes further research of an approach to significantly enhance the key exchange rate in an optical fiber system at distances in the range of 1-20km. We will present results on a number of application scenarios, including point-to-point links and multi-user networks. Quantum key distribution systems have been developed, which use standard telecommunications optical fiber, and which are capable of operating at clock rates of up to 2GHz. They implement a polarization-encoded version of the B92 protocol and employ vertical-cavity surface-emitting lasers with emission wavelengths of 850 nm as weak coherent light sources, as well as silicon single-photon avalanche diodes as the single photon detectors. The point-to-point quantum key distribution system exhibited a quantum bit error rate of 1.4%, and an estimated net bit rate greater than 100,000 bits-1 for a 4.2 km transmission range.

Shaping the professional landscape through research, advocacy and education - an Australian perspective.

PubMed

Siemensma, Gemma; Ritchie, Ann; Lewis, Suzanne

2017-06-01

This article is the first in a new series in this regular feature. The intention of the series is to look at important global developments in health science libraries. Librarians will be invited to share with HILJ readers key initiatives in their country or region. These articles should serve as a road map, describing the key changes in the field and exploring factors driving these changes. We initiate this series with an article by three Australian librarians who use research findings to depict the evolving professional landscape in their country. The starting point of their analysis is a report completed in 2011 which looked into likely future workforce and education requirements for health library professionals. The authors trace the achievements since then, most notably in the areas of research, advocacy and education. Clearly, a great deal has been achieved leading to a greater return on investment. The authors maintain that the key to shaping the profession and enhancing the status of librarians is ongoing professional development. To this end, Australia is promoting a systematic, competency based health specialist certification. Finally, they identify trends impacting on health librarianship, such as the growing importance of research data management and consumer health literacy. JM. © 2017 Health Libraries Group.

Multisociety Task Force for Critical Care Research: key issues and recommendations.

PubMed

Deutschman, Clifford S; Ahrens, Tom; Cairns, Charles B; Sessler, Curtis N; Parsons, Polly E

2012-01-01

Research in critical care extends from the bench to the bedside, involving multiple departments, specialties, and funding organizations. Because of this diversity, it has been difficult for all stakeholders to collectively identify challenges and establish priorities. To define a comprehensive agenda for critical care research using input from a broad range of stakeholders to serve as a blueprint for future initiatives. The Critical Care Societies Collaborative (CCSC), consisting of the leadership of the American Association of Critical-Care Nurses (AACN), the American College of Chest Physicians (ACCP), the American Thoracic Society (ATS), and the Society of Critical Care Medicine (SCCM), joined the US Critical Illness and Injury Trials Group (USCIITG) in forming a task force to define a comprehensive critical care research agenda. This group of 25 identified experts was divided into subgroups to address basic, translational, clinical, implementation, and educational research. The subgroups met via conference calls, and the entire task force met in person for a 2-day session. The result was a detailed discussion of the research priorities that served as the basis for this report. The task force identified challenges, specific priority areas, and recommendations for process improvements to support critical care research. Additionally, four overarching themes emerged: 1) the traditional "silo-ed" approach to critical care research is counterproductive and should be modified; 2) an approach that more effectively links areas of research (i.e., basic and translational research, or clinical research and implementation) should be embraced; 3) future approaches to human research should account for disease complexity and patient heterogeneity; and 4) an enhanced infrastructure for critical care research is essential for future success. This document contains the themes/recommendations developed by a large, multiprofessional cross section of critical care scientists, clinicians, and educators. It provides a unique framework for future research in critical care medicine.

Multisociety task force for critical care research: key issues and recommendations.

PubMed

Deutschman, Clifford S; Ahrens, Tom; Cairns, Charles B; Sessler, Curtis N; Parsons, Polly E

2012-01-01

Research in critical care extends from the bench to the bedside, involving multiple departments, specialties, and funding organizations. Because of this diversity, it has been difficult for all stakeholders to collectively identify challenges and establish priorities. To define a comprehensive agenda for critical care research using input from a broad range of stakeholders to serve as a blueprint for future initiatives. The Critical Care Societies Collaborative (CCSC), consisting of the leadership of the American Association of Critical-Care Nurses (AACN), the American College of Chest Physicians (ACCP), the American Thoracic Society (ATS), and the Society of Critical Care Medicine (SCCM), joined the U.S. Critical Illness and Injury Trials Group (USCIITG) in forming a task force to define a comprehensive critical care research agenda. This group of 25 identified experts was divided into subgroups to address basic, translational, clinical, implementation, and educational research. The subgroups met via conference calls, and the entire task force met in person for a 2-day session. The result was a detailed discussion of the research priorities that served as the basis for this report. The task force identified challenges, specific priority areas, and recommendations for process improvements to support critical care research. Additionally, four overarching themes emerged: (1) the traditional "silo-ed" approach to critical care research is counterproductive and should be modified; (2) an approach that more effectively links areas of research (i.e., basic and translational research, or clinical research and implementation) should be embraced; (3) future approaches to human research should account for disease complexity and patient heterogeneity; and (4) an enhanced infrastructure for critical care research is essential for future success. This document contains the themes/recommendations developed by a large, multiprofessional cross-section of critical care scientists, clinicians, and educators. It provides a unique framework for future research in critical care medicine.

Multisociety task force for critical care research: key issues and recommendations.

PubMed

Deutschman, Clifford S; Ahrens, Tom; Cairns, Charles B; Sessler, Curtis N; Parsons, Polly E

2012-01-01

Research in critical care extends from the bench to the bedside, involving multiple departments, specialties, and funding organizations. Because of this diversity, it has been difficult for all stakeholders to collectively identify challenges and establish priorities. To define a comprehensive agenda for critical care research using input from a broad range of stakeholders to serve as a blueprint for future initiatives. The Critical Care Societies Collaborative (CCSC), consisting of the leadership of the American Association of Critical-Care Nurses (AACN), the American College of Chest Physicians (ACCP), the American Thoracic Society (ATS), and the Society of Critical Care Medicine (SCCM), joined the US Critical Illness and Injury Trials Group (USCIITG) in forming a task force to define a comprehensive critical care research agenda. This group of 25 identified experts was divided into subgroups to address basic, translational, clinical, implementation, and educational research. The subgroups met via conference calls, and the entire task force met in person for a 2-day session. The result was a detailed discussion of the research priorities that served as the basis for this report. The task force identified challenges, specific priority areas, and recommendations for process improvements to support critical care research. Additionally, four overarching themes emerged: 1) the traditional "silo-ed" approach to critical care research is counterproductive and should be modified; 2) an approach that more effectively links areas of research (ie, basic and translational research, or clinical research and implementation) should be embraced; 3) future approaches to human research should account for disease complexity and patient heterogeneity; and 4) an enhanced infrastructure for critical care research is essential for future success. This document contains the themes/recommendations developed by a large, multiprofessional cross section of critical care scientists, clinicians, and educators. It provides a unique framework for future research in critical care medicine.

Multisociety Task Force for Critical Care Research: Key Issues and Recommendations

PubMed Central

Deutschman, Clifford S.; Ahrens, Tom; Cairns, Charles B.; Sessler, Curtis N.; Parsons, Polly E.

2012-01-01

Background: Research in critical care extends from the bench to the bedside, involving multiple departments, specialties, and funding organizations. Because of this diversity, it has been difficult for all stakeholders to collectively identify challenges and establish priorities. Objective: To define a comprehensive agenda for critical care research using input from a broad range of stakeholders to serve as a blueprint for future initiatives. Methods: The Critical Care Societies Collaborative (CCSC), consisting of the leadership of the American Association of Critical-Care Nurses (AACN), the American College of Chest Physicians (ACCP), the American Thoracic Society (ATS), and the Society of Critical Care Medicine (SCCM), joined the U.S. Critical Illness and Injury Trials Group (USCIITG) in forming a task force to define a comprehensive critical care research agenda. This group of 25 identified experts was divided into subgroups to address basic, translational, clinical, implementation, and educational research. The subgroups met via conference calls, and the entire task force met in person for a 2-day session. The result was a detailed discussion of the research priorities that served as the basis for this report. Results: The task force identified challenges, specific priority areas, and recommendations for process improvements to support critical care research. Additionally, four overarching themes emerged: (1) the traditional “silo-ed” approach to critical care research is counterproductive and should be modified; (2) an approach that more effectively links areas of research (i.e., basic and translational research, or clinical research and implementation) should be embraced; (3) future approaches to human research should account for disease complexity and patient heterogeneity; and (4) an enhanced infrastructure for critical care research is essential for future success. Conclusions: This document contains the themes/recommendations developed by a large, multiprofessional cross-section of critical care scientists, clinicians, and educators. It provides a unique framework for future research in critical care medicine. PMID:22210788

University of Kansas Medical center Cancer Research Equipment Award Type: Construction Grant

DOE Office of Scientific and Technical Information (OSTI.GOV)

Caldwell, Jamie

A major mechanism to strengthen the overall cancer focus of KUCC and expand specific research programs is through targeted recruitment of additional cancer researchers to increase the national and international status of the Cancer Center, enhance the number of NCI/cancer-related grants, fill critical research needs, and enable new collaborative projects. Over the last five years KUCC has demonstrated the ability to recruit nationally recognized basic, translational and clinical scientists to fill key leadership positions and strengthen our research programs. These researchers require new and renovated research facilities require state-of-the-art laboratory equipment. This includes standard equipment for the renovated laboratories andmore » more specialized equipment as part of new investigator start-up packages. This funding is used to support recruitment, facilities, equipment, shared resources, administration, and patient care services. KUCC is committed to recruiting additional cancer researchers to increase the national and international status of the Cancer Center, enhance the number of NCI/cancer-related grants, fill critical research positions and build the four cancer research programs. Each purposeful hire aims to further the scientific vision, mission, and goals of the Cancer Center research programs. The funds requested will be used to supplement the recruitment packages of future cancer center recruits primarily through purchase of key equipment items.« less

Developing technology for surgery in the UK: a multidisciplinary meeting of engineers and surgeons.

PubMed

Taylor, G W

2007-03-01

There is an increasing necessity for surgeons and engineers to work together in order to target future technological developments at clinical need and cost-effectiveness. This is a report of two linked meetings with these objectives, held at the Institute of Mechanical Engineers, London, UK. The two meetings were organized by the same faculty members and held on consecutive days. Delegates included surgeons, academic mechanical engineers, researchers and industrial representatives. The programme was made up of varied presentations by surgeons and engineers as well as open discussion of the topics covered. Delegates were updated on the current state of surgical robotics in the UK in four surgical specialties; urology, neurosurgery, orthopaedics and ENT. This included clinical and experimental evidence, together with discussion of future advances. Minimally invasive surgery, real-time imaging and the development of more compact and cost effective surgical robots were identified as key areas for future research. Copyright 2006 John Wiley & Sons, Ltd.

The state of the art and future opportunities for using longitudinal n-of-1 methods in health behaviour research: a systematic literature overview.

PubMed

McDonald, Suzanne; Quinn, Francis; Vieira, Rute; O'Brien, Nicola; White, Martin; Johnston, Derek W; Sniehotta, Falko F

2017-12-01

n-of-1 studies test hypotheses within individuals based on repeated measurement of variables within the individual over time. Intra-individual effects may differ from those found in between-participant studies. Using examples from a systematic review of n-of-1 studies in health behaviour research, this article provides a state of the art overview of the use of n-of-1 methods, organised according to key methodological considerations related to n-of-1 design and analysis, and describes future challenges and opportunities. A comprehensive search strategy (PROSPERO:CRD42014007258) was used to identify articles published between 2000 and 2016, reporting observational or interventional n-of-1 studies with health behaviour outcomes. Thirty-nine articles were identified which reported on n-of-1 observational designs and a range of n-of-1 interventional designs, including AB, ABA, ABABA, alternating treatments, n-of-1 randomised controlled trial, multiple baseline and changing criterion designs. Behaviours measured included treatment adherence, physical activity, drug/alcohol use, sleep, smoking and eating behaviour. Descriptive, visual or statistical analyses were used. We identify scope and opportunities for using n-of-1 methods to answer key questions in health behaviour research. n-of-1 methods provide the tools needed to help advance theoretical knowledge and personalise/tailor health behaviour interventions to individuals.

Perspectives of key stakeholders and experts in infant feeding on the implementation of the Australian National Breastfeeding Strategy 2010-2015.

PubMed

Hull, Naomi S; Schubert, Lisa C; Smith, Julie P

2017-03-01

Breastfeeding is widely accepted as an important public health issue for babies and their mothers. Yet, despite this, Australia continues to struggle with reaching global targets for breastfeeding indicators. In 2007, the Best Start Parliamentary Inquiry Report was released and set the stage for the Australian National Breastfeeding Strategy [2010-2015), which was announced in November 2009, with the vision to increase Australia's breastfeeding rates of infants at 6 months of age and beyond. The aim of this research project was to explore the perspectives of key stakeholders in the field of infant feeding in Australia on the implementation of the strategy, barriers and enablers to its successful implementation and actions that were still needed. Using qualitative research methods of in-depth, semi-structured interviews and thematic analysis, this study identifies main themes of these perceptions about the strategy implementation and some recommendations for future strategies and further research. The main themes identified were initial opinions of the strategy as a blueprint for action, the strategy as a driver for action, lessons learned and recommendations for the future. For success in improving implementation of national breastfeeding strategies, it is recommended that Australia establish an independent breastfeeding/infant feeding committee, increase the political prioritisation of issues surrounding infant feeding and strengthen the regulation of the marketing of breastmilk substitutes.

Classic fungal natural products in the genomic age: the molecular legacy of Harold Raistrick.

PubMed

Schor, Raissa; Cox, Russell

2018-03-01

Covering: 1893 to 2017Harold Raistrick was involved in the discovery of many of the most important classes of fungal metabolites during the 20th century. This review focusses on how these discoveries led to developments in isotopic labelling, biomimetic chemistry and the discovery, analysis and exploitation of biosynthetic gene clusters for major classes of fungal metabolites including: alternariol; geodin and metabolites of the emodin pathway; maleidrides; citrinin and the azaphilones; dehydrocurvularin; mycophenolic acid; and the tropolones. Key recent advances in the molecular understanding of these important pathways, including the discovery of biosynthetic gene clusters, the investigation of the molecular and chemical aspects of key biosynthetic steps, and the reengineering of key components of the pathways are reviewed and compared. Finally, discussion of key relationships between metabolites and pathways and the most important recent advances and opportunities for future research directions are given.

Health-Enabling and Ambient Assistive Technologies: Past, Present, Future.

PubMed

Haux, R; Koch, S; Lovell, N H; Marschollek, M; Nakashima, N; Wolf, K-H

2016-06-30

During the last decades, health-enabling and ambient assistive technologies became of considerable relevance for new informatics-based forms of diagnosis, prevention, and therapy. To describe the state of the art of health-enabling and ambient assistive technologies in 1992 and today, and its evolution over the last 25 years as well as to project where the field is expected to be in the next 25 years. In the context of this review, we define health-enabling and ambient assistive technologies as ambiently used sensor-based information and communication technologies, aiming at contributing to a person's health and health care as well as to her or his quality of life. Systematic review of all original articles with research focus in all volumes of the IMIA Yearbook of Medical Informatics. Surveying authors independently on key projects and visions as well as on their lessons learned in the context of health-enabling and ambient assistive technologies and summarizing their answers. Surveying authors independently on their expectations for the future and summarizing their answers. IMIA Yearbook papers containing statements on health-enabling and ambient assistive technologies appear first in 2002. These papers form a minor part of published research articles in medical informatics. However, during recent years the number of articles published has increased significantly. Key projects were identified. There was a clear progress on the use of technologies. However proof of diagnostic relevance and therapeutic efficacy remains still limited. Reforming health care processes and focussing more on patient needs are required. Health-enabling and ambient assistive technologies remain an important field for future health care and for interdisciplinary research. More and more publications assume that a person's home and their interaction therein, are becoming important components in health care provision, assessment, and management.

Health-Enabling and Ambient Assistive Technologies: Past, Present, Future

PubMed Central

2016-01-01

Summary Background During the last decades, health-enabling and ambient assistive technologies became of considerable relevance for new informatics-based forms of diagnosis, prevention, and therapy. Objectives To describe the state of the art of health-enabling and ambient assistive technologies in 1992 and today, and its evolution over the last 25 years as well as to project where the field is expected to be in the next 25 years. In the context of this review, we define health-enabling and ambient assistive technologies as ambiently used sensor-based information and communication technologies, aiming at contributing to a person’s health and health care as well as to her or his quality of life. Methods Systematic review of all original articles with research focus in all volumes of the IMIA Yearbook of Medical Informatics. Surveying authors independently on key projects and visions as well as on their lessons learned in the context of health-enabling and ambient assistive technologies and summarizing their answers. Surveying authors independently on their expectations for the future and summarizing their answers. Results IMIA Yearbook papers containing statements on health-enabling and ambient assistive technologies appear first in 2002. These papers form a minor part of published research articles in medical informatics. However, during recent years the number of articles published has increased significantly. Key projects were identified. There was a clear progress on the use of technologies. However proof of diagnostic relevance and therapeutic efficacy remains still limited. Reforming health care processes and focussing more on patient needs are required. Conclusions Health-enabling and ambient assistive technologies remain an important field for future health care and for interdisciplinary research. More and more publications assume that a person‘s home and their interaction therein, are becoming important components in health care provision, assessment, and management. PMID:27362588

The life cycle of a genome project: perspectives and guidelines inspired by insect genome projects

PubMed Central

Papanicolaou, Alexie

2016-01-01

Many research programs on non-model species biology have been empowered by genomics. In turn, genomics is underpinned by a reference sequence and ancillary information created by so-called “genome projects”. The most reliable genome projects are the ones created as part of an active research program and designed to address specific questions but their life extends past publication. In this opinion paper I outline four key insights that have facilitated maintaining genomic communities: the key role of computational capability, the iterative process of building genomic resources, the value of community participation and the importance of manual curation. Taken together, these ideas can and do ensure the longevity of genome projects and the growing non-model species community can use them to focus a discussion with regards to its future genomic infrastructure. PMID:27006757

[Social marketing and public policies for health: campaign to promote smoke-free spaces in Mexico].

PubMed

Villalobos, Víctor; Ramírez, Olivia Ortiz; Thrasher, James F; Santillán, Edna Arillo; Hernández, Rosaura Pérez; Cedillo, Claudia; González, Wendy

2010-01-01

"Porque todos respiramos lo mismo" is a mass media campaign to promote smoke-free places (SFP). The development stages were: strategic planning; formative research; message development; media plan; and impact evaluation. Development involved formation of a coalition of key actors in various sectors. The target population was smokers and nonsmokers, with the aim of changing social norms around SFP. Nonsmokers were targeted because they comprised the majority and were most likely to appreciate the benefits of SFPs. Campaign materials were aired on television, radio, print and on billboards. One key limitation was the lack of evidence for previous campaigns, which increased the importance of formative research and of including a rigorous evaluation for this one. The campaign evaluation indicates a significant impact, which suggests that future campaigns use similar strategies in their development.

The life cycle of a genome project: perspectives and guidelines inspired by insect genome projects.

PubMed

Papanicolaou, Alexie

2016-01-01

Many research programs on non-model species biology have been empowered by genomics. In turn, genomics is underpinned by a reference sequence and ancillary information created by so-called "genome projects". The most reliable genome projects are the ones created as part of an active research program and designed to address specific questions but their life extends past publication. In this opinion paper I outline four key insights that have facilitated maintaining genomic communities: the key role of computational capability, the iterative process of building genomic resources, the value of community participation and the importance of manual curation. Taken together, these ideas can and do ensure the longevity of genome projects and the growing non-model species community can use them to focus a discussion with regards to its future genomic infrastructure.

SO x /NO x Removal from Flue Gas Streams by Solid Adsorbents: A Review of Current Challenges and Future Directions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rezaei, Fateme; Rownaghi, Ali A.; Monjezi, Saman

One of the main challenges in the power and chemical industries is to remove generated toxic or environmentally harmful gases before atmospheric emission. To comply with stringent environmental and pollutant emissions control regulations, coal-fired power plants must be equipped with new technologies that are efficient and less energy-intensive than status quo technologies for flue gas cleanup. While conventional sulfur oxide (SOx) and nitrogen oxide (NOx) removal technologies benefit from their large-scale implementation and maturity, they are quite energy-intensive. In view of this, the development of lower-cost, less energy-intensive technologies could offer an advantage. Significant energy and cost savings can potentiallymore » be realized by using advanced adsorbent materials. One of the major barriers to the development of such technologies remains the development of materials that are efficient and productive in removing flue gas contaminants. In this review, adsorption-based removal of SOx/NOx impurities from flue gas is discussed, with a focus on important attributes of the solid adsorbent materials as well as implementation of the materials in conventional and emerging acid gas removal technologies. The requirements for effective adsorbents are noted with respect to their performance, key limitations, and suggested future research directions. The final section includes some key areas for future research and provides a possible roadmap for the development of technologies for the removal of flue gas impurities that are more efficient and cost-effective than status quo approaches.« less

USDA Biochar Research: Land Application Advances to Reap Its Multifunctional Abilities

NASA Astrophysics Data System (ADS)

Ippolito, J.; Spokas, K.; Novak, J.; Lentz, R. D.; Stromberger, M.; Ducey, T.; Johnson, M.

2014-12-01

Biochar is the solid byproduct from the pyrolysis of agricultural crop residues, manures, green wastes and wood-based materials. Pyrolyzing biomass causes inorganic and organic compounds to be concentrated within the carbonized remains of the original lignin and cellulose structure. It is through this complex mixture of organic aromatic structures and inorganic elements that potentially imparts biochars with special multi-functional capabilities. Our current research has focused on developing biochar to simultaneously sequester soil carbon and remediate degraded soils. This is accomplished by directly improving soil nutrient and moisture contents, sorbing pollutants, as well as altering microbial signaling. Maintaining these improvements needs to account for biochar physical degradation, which may be overcome by biochar-mineral associations. Additional research is focused on biochar use that minimizes soil microorganism population shifts in order to maintain current ecosystem services. Future USDA research involves more evaluations to understand the multifunctional role of biochar in the agricultural and environmental sectors (e.g., USEPA superfund locations). This presentation will provide highlights of current and future coordinated biochar research efforts from several key laboratory locations across the US.

Plasmodium vivax Biology: Insights Provided by Genomics, Transcriptomics and Proteomics

PubMed Central

Bourgard, Catarina; Albrecht, Letusa; Kayano, Ana C. A. V.; Sunnerhagen, Per; Costa, Fabio T. M.

2018-01-01

During the last decade, the vast omics field has revolutionized biological research, especially the genomics, transcriptomics and proteomics branches, as technological tools become available to the field researcher and allow difficult question-driven studies to be addressed. Parasitology has greatly benefited from next generation sequencing (NGS) projects, which have resulted in a broadened comprehension of basic parasite molecular biology, ecology and epidemiology. Malariology is one example where application of this technology has greatly contributed to a better understanding of Plasmodium spp. biology and host-parasite interactions. Among the several parasite species that cause human malaria, the neglected Plasmodium vivax presents great research challenges, as in vitro culturing is not yet feasible and functional assays are heavily limited. Therefore, there are gaps in our P. vivax biology knowledge that affect decisions for control policies aiming to eradicate vivax malaria in the near future. In this review, we provide a snapshot of key discoveries already achieved in P. vivax sequencing projects, focusing on developments, hurdles, and limitations currently faced by the research community, as well as perspectives on future vivax malaria research. PMID:29473024

Research on biomass energy and environment from the past to the future: A bibliometric analysis.

PubMed

Mao, Guozhu; Huang, Ning; Chen, Lu; Wang, Hongmei

2018-09-01

The development and utilization of biomass energy can help to change the ways of energy production and consumption and establish a sustainable energy system that can effectively promote the development of the national economy and strengthen the protection of the environment. Here,we perform a bibliometric analysis of 9514 literature reports in the Web of Science Core Collection searched with the key words "Biomass energy" and "Environment*" date from 1998 to 2017; hot topics in the research and development of biomass energy utilization, as well as the status and development trends of biomass energy utilization and the environment, were analyzed based on content analysis and bibliometrics. The interaction between biomass energy and the environment began to become a major concern as the research progressively deepened. This work is of great significance for the development and utilization of biomass energy to put forward specific suggestions and strategies based on the analysis and demonstration of relationships and interactions between biomass energy utilization and environment. It is also useful to researchers for selecting the future research topics. Copyright © 2018 Elsevier B.V. All rights reserved.

Using Theories of Change to inform implementation of health systems research and innovation: experiences of Future Health Systems consortium partners in Bangladesh, India and Uganda.

PubMed

Paina, Ligia; Wilkinson, Annie; Tetui, Moses; Ekirapa-Kiracho, Elizabeth; Barman, Debjani; Ahmed, Tanvir; Mahmood, Shehrin Shaila; Bloom, Gerry; Knezovich, Jeff; George, Asha; Bennett, Sara

2017-12-28

The Theory of Change (ToC) is a management and evaluation tool supporting critical thinking in the design, implementation and evaluation of development programmes. We document the experience of Future Health Systems (FHS) Consortium research teams in Bangladesh, India and Uganda with using ToC. We seek to understand how and why ToCs were applied and to clarify how they facilitate the implementation of iterative intervention designs and stakeholder engagement in health systems research and strengthening. This paper combines literature on ToC, with a summary of reflections by FHS research members on the motivation, development, revision and use of the ToC, as well as on the benefits and challenges of the process. We describe three FHS teams' experiences along four potential uses of ToCs, namely planning, communication, learning and accountability. The three teams developed ToCs for planning and evaluation purposes as required for their initial plans for FHS in 2011 and revised them half-way through the project, based on assumptions informed by and adjusted through the teams' experiences during the previous 2 years of implementation. All teams found that the revised ToCs and their accompanying narratives recognised greater feedback among intervention components and among key stakeholders. The ToC development and revision fostered channels for both internal and external communication, among research team members and with key stakeholders, respectively. The process of revising the ToCs challenged the teams' initial assumptions based on new evidence and experience. In contrast, the ToCs were only minimally used for accountability purposes. The ToC development and revision process helped FHS research teams, and occasionally key local stakeholders, to reflect on and make their assumptions and mental models about their respective interventions explicit. Other projects using the ToC should allow time for revising and reflecting upon the ToCs, to recognise and document the adaptive nature of health systems, and to foster the time, space and flexibility that health systems strengthening programmes must have to learn from implementation and stakeholder engagement.

Adult sibling experience, roles, relationships and future concerns - a review of the literature in learning disabilities.

PubMed

Davys, Deborah; Mitchell, Duncan; Haigh, Carol

2011-10-01

This paper provides a review of the literature related to adult siblings of learning-disabled people. Siblings of learning-disabled people are often looked upon as next of kin when older parents die; however, there is little research regarding sibling views and wishes. A literature review of published peer-reviewed empirical research was undertaken. Electronic databases and citation tracking were used to collate data using key terms such as adult siblings and learning disability. Relevant articles were analysed, compared and contrasted. Six key themes emerged suggesting a varied impact of learning disability upon sibling lives in areas that include life choices, relationships, identity and future plans. Some siblings report a positive impact upon life, others state their lives are comparable with other adults who do not have a learning-disabled sibling and others still report a negative impact. Sibling roles and relationships are varied. Evidence suggests that sibling roles, relationships and experience are affected by life stage. Parents often have a primary care role for the disabled person, whilst siblings perform a more distant role; however, sibling involvement often rises when parents are no longer able to provide previous levels of support. Many factors appear to affect the sibling experience and uptake of roles including gender, life stage and circumstances, level of disability, health status and relationships between family members. Siblings are concerned about the future, particularly when parents are no longer able to provide support, and many appear to have expectations of future responsibilities regarding their disabled sibling. As siblings of people who have a learning disability are often expected by society to provide support, it is important that health and social care practitioners are aware of issues that may impact on this relationship. © 2011 Blackwell Publishing Ltd.

Communication that heals: mindful communication practices from palliative care leaders.

PubMed

Omilion-Hodges, Leah M; Swords, Nathan M

2016-01-01

Though research has begun to highlight the centrality of communication in palliative care, studies have yet to focus on the use of mindful communication. Mindful communication is associated with increases in patient care and decreases in physician burnout. Through in-depth, semi-structured interviews the authors sought mindful communication practices from palliative care leaders in American Hospital Association Circle of Life® award-wining units. Four key mindful communication practices emerged: Know your audience, ask questions, discard scripts, and recognize your role. The discussion articulates how key mindful communication practices may be used as a stage model, where key practices may be used individually or in concert, by sole practitioners or within interdisciplinary teams and by new and seasoned clinicians. Theoretical contributions and areas for future inquiry are also discussed.

Physical Activity and Pregnancy: Past and Present Evidence and Future Recommendations

PubMed Central

Downs, Danielle Symons; Chasan-Taber, Lisa; Evenson, Kelly R.; Leiferman, Jenn; Yeo, SeonAe

2012-01-01

Purpose This review provides researchers and practitioners with an overview of the physical activity and pregnancy literature to promote prenatal physical activity, improve measurement, further elucidate the role of activity in reducing maternal health complications, and inform future research. Methods We examined past and present physical activity and pregnancy studies and highlight key papers with a particular focus on maternal health outcomes to best inform physical activity promotion efforts. Results This review discusses: (a) historical overview of prenatal physical activity with a specific focus on the physical activity guidelines, how they have changed over time, and how evidence of the effect of prenatal activity on maternal/fetal health outcomes has impacted clinical recommendations; (b) existing tools and challenges associated with measuring prenatal physical activity; (c) empirical evidence on the multi-level determinants of prenatal activity to help guide future intervention work; (d) empirical evidence of prenatal activity on adverse maternal outcomes (gestational diabetes mellitus, preeclampsia, excessive gestational weight gain) from observational and intervention studies; and (e) summary/recommendations for future research and practice. Conclusions The physical activity and pregnancy literature has evolved over the past 50 years and there is currently sufficient empirical evidence to support the promotion of moderate to vigorous prenatal physical activity for maternal health benefits. Future studies and interventions should be carefully-designed, theoretically driven, and include validated and reliable measures of activity. Researchers and practitioners should also consider the multifaceted determinants and outcomes of prenatal physical activity and intervening to promote physical activity before, during, and after pregnancy. PMID:23367811

Nanoscience Research for Energy Needs

DTIC Science & Technology

2005-06-01

demonstrated using highly defective nanoscale inorganic materials in battery chemistry (e.g., Li-ion insertion into V2O5 aerogels at unprecedented Li-to...devices. One future path of nanoscale design and synthesis of disordered high-performance energy materials may be to mimic glass science; however, to...stabilize a technically important but unstable glass composition, another ingredient may be necessary. Computational chemistry will be key in selecting

The Impact of Supply and Demand on Doctorates in Physical Education Teacher Education: The Future of the Profession

ERIC Educational Resources Information Center

Boyce, Barbara Ann; Lund, Jackie; O'Neil, Kason

2016-01-01

Quality preparation of doctoral students is a key to the survival of physical education teacher education. Past research has revealed a shortage of students graduating with a doctoral degree in physical education and a general reluctance of teachers to leave their jobs to pursue an advanced degree. As the number of universities preparing new…

Building a collaborative network to understand regional forest dynamics and advance forestry initiatives in the Caribbean

Treesearch

Grizelle Gonzalez; Tamara Heartsill Scalley

2016-01-01

Herein we provide concluding remarks drawn from and inspired by the discussions of the 5 working groups of the 16th Caribbean Foresters Meeting (CFM) about the needs, challenges, and recommendations to advance forestry in the Caribbean region. We also list key considerations and potential future research directions as presented in the various manuscripts contained in...

The New Forgotten Half and Research Directions to Support Them. Summary and Key Findings. A William T. Grant Foundation Inequality Paper

ERIC Educational Resources Information Center

Rosenbaum, James; Ahearn, Caitlin; Becker, Kelly; Rosenbaum, Janet

2015-01-01

In 1988, the William T. Grant Foundation issued "The Forgotten Half," the final report of the Foundation's Commission on Youth and America's Future. Focusing on inequality in American society, specifically among non-college-bound 16-24 year olds, the report explored the challenges facing young people and the institutions that serve them.…

Measuring Learning Outcomes in Higher Education Using the Measure of Academic Proficiency and Progress (MAPP). Research Report. ETS RR-08-47

ERIC Educational Resources Information Center

Liu, Ou Lydia

2008-01-01

The Secretary of Education's Commission on the Future of Higher Education emphasizes accountability in higher education as one of the key areas of interest. The Voluntary System of Accountability (VSA) was developed to evaluate the effectiveness of general public college education. This study examines how student progress in college, indicated by…

Teachers' and Students' Music Preferences for Secondary School Music Lessons: Reasons and Implications

ERIC Educational Resources Information Center

McQueen, Hilary; Hallam, Susan; Creech, Andrea

2018-01-01

This paper is based on the data collected from a longitudinal study of seven maintained, secondary schools in England that have adopted Musical Futures as an approach to teaching music. The research had a particular focus on key stage 3 (11-14). For the purposes of this paper, data gained from 18 music staff and 325 student interview…

Piecing Together the Puzzle of Graduate Employment: Factors that Shape the Graduate Work Expectations of Human Resource Management Students

ERIC Educational Resources Information Center

Parris, Melissa A.; Saville, Kerrie

2011-01-01

Providing graduates with a set of skills and attributes relevant to their future employment remains a key topic in both higher education policy and research. This paper reports findings from a pilot study of human resource management (HRM) students' perceptions of the graduate work experience. Specifically, it focuses on how these perceptions are…

Demonstration of Self-Training Autonomous Neural Networks in Space Vehicle Docking Simulations

NASA Technical Reports Server (NTRS)

Patrick, M. Clinton; Thaler, Stephen L.; Stevenson-Chavis, Katherine

2006-01-01

Neural Networks have been under examination for decades in many areas of research, with varying degrees of success and acceptance. Key goals of computer learning, rapid problem solution, and automatic adaptation have been elusive at best. This paper summarizes efforts at NASA's Marshall Space Flight Center harnessing such technology to autonomous space vehicle docking for the purpose of evaluating applicability to future missions.

H5N1 influenza viruses: facts, not fear.

PubMed

Palese, Peter; Wang, Taia T

2012-02-14

The ongoing controversy over publication of two studies involving the transmission in ferrets of H5N1 (H5) subtype influenza viruses and the recommendations of the National Science Advisory Board for Biosecurity to redact key details in the manuscripts call for an examination of relevant scientific facts. In addition, there are calls in the media to destroy the viruses, curtail future research in this area, and protect the public from such "frightening" research efforts. Fear needs to be put to rest with solid science and not speculation.

Performance Factors Related to the Different Tennis Backhand Groundstrokes: A Review

PubMed Central

Genevois, Cyril; Reid, Machar; Rogowski, Isabelle; Crespo, Miguel

2015-01-01

The backhand is one of the two basic groundstrokes in tennis and can be played both with one or two hands, with topspin or backspin. Despite its variety of derivatives, the scientific literature describing the backhand groundstroke production has not been reviewed as extensively as with the serve and the forehand. The purpose of this article is to review the research describing the mechanics of one and two-handed backhands, with a critical focus on its application to clinicians and coaches. One hundred and thirty four articles satisfied a key word search (tennis, backhand) in relevant databases and manual search, with only 61 of those articles considered directly relevant to our review. The consensus of this research supports major differences between both the one- and two-handed strokes, chiefly about their respective contributions of trunk rotation and the role of the non-dominant upper extremity. Two-handed backhand strokes rely more on trunk rotation for the generation of racquet velocity, while the one-handed backhands utilize segmental rotations of the upper limb to develop comparable racquet speeds. There remains considerable scope for future research to examine expertise, age and/or gender-related kinematic differences to strengthen the practitioner’s understanding of the key mechanical considerations that may shape the development of proficient backhand strokes. Key points One-and two-handed backhands require different motor coordination Two-handed backhand strokes rely more on trunk rotation for racquet velocity generation, whereas one-handed backhand strokes rely more on segmental rotations of the upper limb Players using a two-handed backhand should learn early a slice one-handed backhand because of the different co-ordination pattern involved Equipment scaling is a great tool for coaches to learn early proper one-handed backhand strokes Future research related to the interaction between backhand technique, gender and skill level is needed PMID:25729308

A report on the Academic Emergency Medicine 2015 consensus conference "Diagnostic imaging in the emergency department: a research agenda to optimize utilization".

PubMed

Gunn, Martin L; Marin, Jennifer R; Mills, Angela M; Chong, Suzanne T; Froemming, Adam T; Johnson, Jamlik O; Kumaravel, Manickam; Sodickson, Aaron D

2016-08-01

In May 2015, the Academic Emergency Medicine consensus conference "Diagnostic imaging in the emergency department: a research agenda to optimize utilization" was held. The goal of the conference was to develop a high-priority research agenda regarding emergency diagnostic imaging on which to base future research. In addition to representatives from the Society of Academic Emergency Medicine, the multidisciplinary conference included members of several radiology organizations: American Society for Emergency Radiology, Radiological Society of North America, the American College of Radiology, and the American Association of Physicists in Medicine. The specific aims of the conference were to (1) understand the current state of evidence regarding emergency department (ED) diagnostic imaging utilization and identify key opportunities, limitations, and gaps in knowledge; (2) develop a consensus-driven research agenda emphasizing priorities and opportunities for research in ED diagnostic imaging; and (3) explore specific funding mechanisms available to facilitate research in ED diagnostic imaging. Through a multistep consensus process, participants developed targeted research questions for future research in six content areas within emergency diagnostic imaging: clinical decision rules; use of administrative data; patient-centered outcomes research; training, education, and competency; knowledge translation and barriers to imaging optimization; and comparative effectiveness research in alternatives to traditional computed tomography use.

The Human Microbiome and Understanding the 16S rRNA Gene in Translational Nursing Science.

PubMed

Ames, Nancy J; Ranucci, Alexandra; Moriyama, Brad; Wallen, Gwenyth R

As more is understood regarding the human microbiome, it is increasingly important for nurse scientists and healthcare practitioners to analyze these microbial communities and their role in health and disease. 16S rRNA sequencing is a key methodology in identifying these bacterial populations that has recently transitioned from use primarily in research to having increased utility in clinical settings. The objectives of this review are to (a) describe 16S rRNA sequencing and its role in answering research questions important to nursing science; (b) provide an overview of the oral, lung, and gut microbiomes and relevant research; and (c) identify future implications for microbiome research and 16S sequencing in translational nursing science. Sequencing using the 16S rRNA gene has revolutionized research and allowed scientists to easily and reliably characterize complex bacterial communities. This type of research has recently entered the clinical setting, one of the best examples involving the use of 16S sequencing to identify resistant pathogens, thereby improving the accuracy of bacterial identification in infection control. Clinical microbiota research and related requisite methods are of particular relevance to nurse scientists-individuals uniquely positioned to utilize these techniques in future studies in clinical settings.

A review of electrostatic monitoring technology: The state of the art and future research directions

NASA Astrophysics Data System (ADS)

Wen, Zhenhua; Hou, Junxing; Atkin, Jason

2017-10-01

Electrostatic monitoring technology is a useful tool for monitoring and detecting component faults and degradation, which is necessary for system health management. It encompasses three key research areas: sensor technology; signal detection, processing and feature extraction; and verification experimentation. It has received considerable recent attention for condition monitoring due to its ability to provide warning information and non-obstructive measurements on-line. A number of papers in recent years have covered specific aspects of the technology, including sensor design optimization, sensor characteristic analysis, signal de-noising and practical applications of the technology. This paper provides a review of the recent research and of the development of electrostatic monitoring technology, with a primary emphasis on its application for the aero-engine gas path. The paper also presents a summary of some of the current applications of electrostatic monitoring technology in other industries, before concluding with a brief discussion of the current research situation and possible future challenges and research gaps in this field. The aim of this paper is to promote further research into this promising technology by increasing awareness of both the potential benefits of the technology and the current research gaps.

A flexible continuous-variable QKD system using off-the-shelf components

NASA Astrophysics Data System (ADS)

Comandar, Lucian C.; Brunner, Hans H.; Bettelli, Stefano; Fung, Fred; Karinou, Fotini; Hillerkuss, David; Mikroulis, Spiros; Wang, Dawei; Kuschnerov, Maxim; Xie, Changsong; Poppe, Andreas; Peev, Momtchil

2017-10-01

We present the development of a robust and versatile CV-QKD architecture based on commercially available optical and electronic components. The system uses a pilot tone for phase synchronization with a local oscillator, as well as local feedback loops to mitigate frequency and polarization drifts. Transmit and receive-side digital signal processing is performed fully in software, allowing for rapid protocol reconfiguration. The quantum link is complemented with a software stack for secure-key processing, key storage and encrypted communication. All these features allow for the system to be at the same time a prototype for a future commercial product and a research platform.

Goal commitment and the goal-setting process: conceptual clarification and empirical synthesis.

PubMed

Klein, H J; Wesson, M J; Hollenbeck, J R; Alge, B J

1999-12-01

Goals are central to current treatments of work motivation, and goal commitment is a critical construct in understanding the relationship between goals and task performance. Despite this importance, there is confusion about the role of goal commitment and only recently has this key construct received the empirical attention it warrants. This meta-analysis, based on 83 independent samples, updates the goal commitment literature by summarizing the accumulated evidence on the antecedents and consequences of goal commitment. Using this aggregate empirical evidence, the role of goal commitment in the goal-setting process is clarified and key areas for future research are identified.

The study of direct-to-consumer advertising for prescription drugs.

PubMed

Schommer, Jon C; Hansen, Richard A

2005-06-01

The objectives of this article are to (1) identify key methodological issues related to investigating the effects of direct-to-consumer advertising (DTCA) for prescription drugs, (2) highlight opportunities and challenges that these issues pose, and (3) provide suggestions to address these challenges and opportunities from a social and administrative pharmacy perspective. Through a review of existing literature and consultation with research colleagues, we identified 3 broad issues regarding the study of DTCA for prescription drugs: (1) the importance of problem formulation, (2) the role of health behavior and decision-making perspectives, and (3) data collection and data analysis challenges and opportunities. Based upon our findings, we developed recommendations for future research in this area. Clear problem formulation will be instructive for prioritizing research needs and for determining the role that health behavior and decision-making perspectives can serve in DTCA research. In addition, it appears that cluster bias, nonlinear relationships, mediating/moderating effects, time effects, acquiescent response, and case mix are particularly salient challenges for the DTCA research domain. We suggest that problem formulation, selection of sound theories upon which to base research, and data collection and data analysis challenges are key methodological issues related to investigating the effects of DTCA for prescription drugs.

Peer relations, adolescent behavior, and public health research and practice.

PubMed

Crosnoe, Robert; McNeely, Clea

2008-01-01

Peer relations are central to adolescent life and, therefore, are crucial to understanding adolescents' engagement in various behaviors. In recent years, public health research has increasingly devoted attention to the implications of peer relations for the kinds of adolescent behaviors that have a direct impact on health. This article advocates for a continuation of this trend. With this aim, we highlight key themes in the rich literature on the general developmental significance of adolescent-peer relations, provide an overview of how these themes have been incorporated into public health research and practice, and suggest future avenues for peer-focused public health research that can inform adolescent health promotion in the United States.

Technologies and combination therapies for enhancing movement training for people with a disability

PubMed Central

2012-01-01

There has been a dramatic increase over the last decade in research on technologies for enhancing movement training and exercise for people with a disability. This paper reviews some of the recent developments in this area, using examples from a National Science Foundation initiated study of mobility research projects in Europe to illustrate important themes and key directions for future research. This paper also reviews several recent studies aimed at combining movement training with plasticity or regeneration therapies, again drawing in part from European research examples. Such combination therapies will likely involve complex interactions with motor training that must be understood in order to achieve the goal of eliminating severe motor impairment. PMID:22463132

Toward a cognitive-affective model of goal-setting in rehabilitation: is self-regulation theory a key step?

PubMed

Siegert, Richard J; McPherson, Kathryn M; Taylor, William J

2004-10-21

The aim of this article is to argue that self-regulation theory might offer a useful model for clinical practice, theory-building and empirical research on goal-setting in rehabilitation. Relevant literature on goal-setting and motivation in rehabilitation is considered and some problematic issues for current practice and future research are highlighted. Carver and Scheier's self-regulation theory and its application to rehabilitation research is examined. It is argued that self-regulation theory offers a robust theoretical framework for goal-setting and one in which the salient concepts of motivation and emotion are prominent. Self-regulation theory offers a potentially useful heuristic framework for rehabilitation research.

Promoting sustainable research partnerships: a mixed-method evaluation of a United Kingdom-Africa capacity strengthening award scheme.

PubMed

Dean, Laura; Njelesani, Janet; Smith, Helen; Bates, Imelda

2015-12-23

Research partnerships between high-income countries (HICs) and low- or middle-income countries (LMICs) are a leading model in research capacity strengthening activities. Although numerous frameworks and guiding principles for effective research partnerships exist, few include the perspective of the LMIC partner. This paper draws out lessons for establishing and maintaining successful research collaborations, based on partnership dynamics, from the perspectives of both HIC and LMIC stakeholders through the evaluation of a research capacity strengthening partnership award scheme. A mixed-method retrospective evaluation approach was used. Initially, a cross-sectional survey was administered to all award holders, which focused on partnership outputs and continuation. Fifty individuals were purposively selected to participate in interviews or focus group discussions from 12 different institutions in HICs and LMICs; the sample included the research investigators, research assistants, laboratory scientists and post-doctoral students. The evaluation collected data on critical elements of research partnership dynamics such as research outputs, nature of the partnership, future plans and research capacity. Quantitative data were analysed descriptively and qualitative data were analysed using an iterative framework approach. The majority of United Kingdom and African award holders stated they would like to pursue future collaborations together. Key aspects within partnerships that appeared to influence this were; the perceived benefits of the partnership at the individual and institutional level such as publication of papers or collaborative grants; ability to influence 'research culture' and instigate critical thinking among mid-career researchers; previous working relationships, for example supervisor-student relationships; and equity within partnerships linked to partnership formation and experience of United Kingdom partners within LMICs. Factors which may hinder development of long term partnerships were also identified such as financial control or differing expectations of partners. This paper provides evidence of what encourages international research partnerships for capacity strengthening to continue past award tenure, from the perspective of researchers in high and LMICs. Although every partnership is unique and individual experiences subjective, this paper provides extension and support of key principles and mechanisms that can contribute to successful research partnerships between researchers.

Facilitating comparative effectiveness research in cancer genomics: evaluating stakeholder perceptions of the engagement process

PubMed Central

Deverka, Patricia A; Lavallee, Danielle C; Desai, Priyanka J; Armstrong, Joanne; Gorman, Mark; Hole-Curry, Leah; O’Leary, James; Ruffner, BW; Watkins, John; Veenstra, David L; Baker, Laurence H; Unger, Joseph M; Ramsey, Scott D

2013-01-01

Aims The Center for Comparative Effectiveness Research in Cancer Genomics completed a 2-year stakeholder-guided process for the prioritization of genomic tests for comparative effectiveness research studies. We sought to evaluate the effectiveness of engagement procedures in achieving project goals and to identify opportunities for future improvements. Materials & methods The evaluation included an online questionnaire, one-on-one telephone interviews and facilitated discussion. Responses to the online questionnaire were tabulated for descriptive purposes, while transcripts from key informant interviews were analyzed using a directed content analysis approach. Results A total of 11 out of 13 stakeholders completed both the online questionnaire and interview process, while nine participated in the facilitated discussion. Eighty-nine percent of questionnaire items received overall ratings of agree or strongly agree; 11% of responses were rated as neutral with the exception of a single rating of disagreement with an item regarding the clarity of how stakeholder input was incorporated into project decisions. Recommendations for future improvement included developing standard recruitment practices, role descriptions and processes for improved communication with clinical and comparative effectiveness research investigators. Conclusions Evaluation of the stakeholder engagement process provided constructive feedback for future improvements and should be routinely conducted to ensure maximal effectiveness of stakeholder involvement. PMID:23459832

Aeronautical Communications Research and Development Needs for Future Air Traffic Management Applications

NASA Technical Reports Server (NTRS)

Kerczewski, Robert J.

2002-01-01

Continuing growth in regional and global air travel has resulted in increasing traffic congestion in the air and on the ground. In spite of occasional temporary downturns due to economic recessions and catastrophic events, average growth rates of air travel have remained high since the 1960s. The resulting congestion, which constrains expansion of the air transportation industry, inflicts schedule delays and decreases overall system efficiency, creating a pressing need to develop more efficient methods of air traffic management (ATM). New ATM techniques, procedures, air space automation methods, and decision support tools are being researched and developed for deployment in time frames stretching from the next few years to the year 2020 and beyond. As these methods become more advanced and increase in complexity, the requirements for information generation, sharing and transfer among the relevant entities in the ATM system increase dramatically. However, current aeronautical communications systems will be inadequate to meet the future information transfer demands created by these advanced ATM systems. Therefore, the NASA Glenn Research Center is undertaking research programs to develop communication, methods and key technologies that can meet these future requirements. As part of this process, studies, workshops, testing and experimentation, and research and analysis have established a number of research and technology development needs. The purpose of this paper is to outline the critical research and technology needs that have been identified in these activities, and explain how these needs have been determined.

Biomimetic materials in the utility industry: A program plan for research opportunities, volume 2. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Richman, R.H.; McNaughton, W.P.

1996-09-01

This report is the second of a two-volume set addressing the state-of-the-art and outlook for the application of biomimetic materials. The first volume examined achievements in mimicking novel aspects of biological systems in five broad categories: (1) Mimicking of Natural Material Designs, (2) Biomimetic Materials Processing, (3) Artificial Photosynthesis, (4) Biomimetic Molecular Electronics, and (5) Biomimetic Catalysis. Each topic was examined as to current activities and approaches, key aspects, unresolved issues, and implications for the power industry. Key researchers, their organizations, the main thrusts of investigation, achievements, and funding agencies were also summarized. This volume highlights opportunities for future researchmore » activities in biomimetics that could be valuable to the U.S. utility industry. Nineteen specific research projects have been identified. These opportunities are outlined in four classes: (1) technology awareness, (2) modeling and experimental studies, (3) state-of-the-art and outlook studies: developing experimental plans, and (4) concept feasibility studies.« less

A Review of Current Neuromorphic Approaches for Vision, Auditory, and Olfactory Sensors.

PubMed

Vanarse, Anup; Osseiran, Adam; Rassau, Alexander

2016-01-01

Conventional vision, auditory, and olfactory sensors generate large volumes of redundant data and as a result tend to consume excessive power. To address these shortcomings, neuromorphic sensors have been developed. These sensors mimic the neuro-biological architecture of sensory organs using aVLSI (analog Very Large Scale Integration) and generate asynchronous spiking output that represents sensing information in ways that are similar to neural signals. This allows for much lower power consumption due to an ability to extract useful sensory information from sparse captured data. The foundation for research in neuromorphic sensors was laid more than two decades ago, but recent developments in understanding of biological sensing and advanced electronics, have stimulated research on sophisticated neuromorphic sensors that provide numerous advantages over conventional sensors. In this paper, we review the current state-of-the-art in neuromorphic implementation of vision, auditory, and olfactory sensors and identify key contributions across these fields. Bringing together these key contributions we suggest a future research direction for further development of the neuromorphic sensing field.

Workshop report: Malaria vaccine development in Europe--preparing for the future.

PubMed

Viebig, Nicola K; D'Alessio, Flavia; Draper, Simon J; Sim, B Kim Lee; Mordmüller, Benjamin; Bowyer, Paul W; Luty, Adrian J F; Jungbluth, Stefan; Chitnis, Chetan E; Hill, Adrian V S; Kremsner, Peter; Craig, Alister G; Kocken, Clemens H M; Leroy, Odile

2015-11-17

The deployment of a safe and effective malaria vaccine will be an important tool for the control of malaria and the reduction in malaria deaths. With the launch of the 2030 Malaria Vaccine Technology Roadmap, the malaria community has updated the goals and priorities for the development of such a vaccine and is now paving the way for a second phase of malaria vaccine development. During a workshop in Brussels in November 2014, hosted by the European Vaccine Initiative, key players from the European, North American and African malaria vaccine community discussed European strategies for future malaria vaccine development in the global context. The recommendations of the European malaria community should guide researchers, policy makers and funders of global health research and development in fulfilling the ambitious goals set in the updated Malaria Vaccine Technology Roadmap. Copyright © 2015.

Exploration-Related Research on the International Space Station: Connecting Science Results to the Design of Future Missions

NASA Technical Reports Server (NTRS)

Rhatigan, Jennifer L.; Robinson, Julie A.; Sawin, Charles F.; Ahlf, Peter R.

2005-01-01

In January, 2004, the US President announced a vision for space exploration, and charged NASA with utilizing the International Space Station (ISS) for research and technology targeted at supporting the US space exploration goals. This paper describes: 1) what we have learned from the first four years of research on ISS relative to the exploration mission, 2) the on-going research being conducted in this regard, 3) our current understanding of the major exploration mission risks that the ISS can be used to address, and 4) current progress in realigning NASA s research portfolio for ISS to support exploration missions. Specifically, we discuss the focus of research on solving the perplexing problems of maintaining human health on long-duration missions, and the development of countermeasures to protect humans from the space environment, enabling long duration exploration missions. The interchange between mission design and research needs is dynamic, where design decisions influence the type of research needed, and results of research influence design decisions. The fundamental challenge to science on ISS is completing experiments that answer key questions in time to shape design decisions for future exploration. In this context, exploration-relevant research must do more than be conceptually connected to design decisions-it must become a part of the mission design process.

Creating an improvement culture for enhanced patient safety: service improvement learning in pre-registration education.

PubMed

Christiansen, Angela; Robson, Linda; Griffith-Evans, Christine

2010-10-01

The present study reports a descriptive survey of nursing students' experience of service improvement learning in the university and practice setting. Opportunities to develop service improvement capabilities were embedded into pre-registration programmes at a university in the Northwest of England to ensure future nurses have key skills for the workplace. A cross-sectional survey designed to capture key aspects of students' experience was completed by nursing students (n = 148) who had undertaken a service improvement project in the practice setting. Work organizations in which a service improvement project was undertaken were receptive to students' efforts. Students reported increased confidence to undertake service improvement and service improvement capabilities were perceived to be important to future career development and employment prospects. Service improvement learning in pre-registration education appears to be acceptable, effective and valued by students. Further research to identify the impact upon future professional practice and patient outcomes would enhance understanding of this developing area. Nurse Managers can play an active role in creating a service culture in which innovation and improvement can flourish to enhance patient outcomes, experience and safety. © 2010 The Authors. Journal compilation © 2010 Blackwell Publishing Ltd.

Strategic management of technostress. The chaining of Prometheus.

PubMed

Caro, D H; Sethi, A S

1985-12-01

The article proposes the concept of technostress and makes a strong recommendation for conducting research based on key researchable hypotheses. A conceptual framework of technostress is suggested to provide some focus to future research. A number of technostress management strategies are put forward, including strategic technological planning, organization culture development, technostress monitoring systems, and technouser self-development programs. The management of technostress is compared to the chaining of Prometheus, which, left uncontrolled, can create havoc in an organization. The authors believe that organizations have a responsibility to introduce, diffuse, and manage computer technology in such a way that it is congruent with the principles of sound, supportive, and humanistic management.

Crew behavior and performance in space analog environments

NASA Technical Reports Server (NTRS)

Kanki, Barbara G.

1992-01-01

The objectives and the current status of the Crew Factors research program conducted at NASA-Ames Research Center are reviewed. The principal objectives of the program are to determine the effects of a broad class of input variables on crew performance and to provide guidance with respect to the design and management of crews assigned to future space missions. A wide range of research environments are utilized, including controlled experimental settings, high fidelity full mission simulator facilities, and fully operational field environments. Key group processes are identified, and preliminary data are presented on the effect of crew size, type, and structure on team performance.

Research and technology

NASA Technical Reports Server (NTRS)

1988-01-01

As the NASA Center responsible for assembly, checkout, servicing, launch, recovery and operational support of Space Transportation System elements and payloads, Kennedy Space Center is placing emphasis on its research and technology program. In addition to strengthening those areas of engineering and operations technology that contribute to safer, more efficient, and more economical execution of our current mission, we are developing the technological tools needed to execute the Center's mission relative to future programs. The Engineering Development Directorate encompasses most of the laboratories and other Center resources that are key elements of research and technology program implementation, and is responsible for implementation of the majority of the projects in this Kennedy Space Center 1988 Annual Report.

Using Community-Based Participatory Research and Human-Centered Design to Address Violence-Related Health Disparities Among Latino/a Youth.

PubMed

Kia-Keating, Maryam; Santacrose, Diana E; Liu, Sabrina R; Adams, Jessica

High rates of exposure to violence and other adversities among Latino/a youth contribute to health disparities. The current article addresses the ways in which community-based participatory research (CBPR) and human-centered design (HCD) can help engage communities in dialogue and action. We present a project exemplifying how community forums, with researchers, practitioners, and key stakeholders, including youths and parents, integrated HCD strategies with a CBPR approach. Given the potential for power inequities among these groups, CBPR + HCD acted as a catalyst for reciprocal dialogue and generated potential opportunity areas for health promotion and change. Future directions are described.

Identification of Crew-Systems Interactions and Decision Related Trends

NASA Technical Reports Server (NTRS)

Jones, Sharon Monica; Evans, Joni K.; Reveley, Mary S.; Withrow, Colleen A.; Ancel, Ersin; Barr, Lawrence

2013-01-01

NASA Vehicle System Safety Technology (VSST) project management uses systems analysis to identify key issues and maintain a portfolio of research leading to potential solutions to its three identified technical challenges. Statistical data and published safety priority lists from academic, industry and other government agencies were reviewed and analyzed by NASA Aviation Safety Program (AvSP) systems analysis personnel to identify issues and future research needs related to one of VSST's technical challenges, Crew Decision Making (CDM). The data examined in the study were obtained from the National Transportation Safety Board (NTSB) Aviation Accident and Incident Data System, Federal Aviation Administration (FAA) Accident/Incident Data System and the NASA Aviation Safety Reporting System (ASRS). In addition, this report contains the results of a review of safety priority lists, information databases and other documented references pertaining to aviation crew systems issues and future research needs. The specific sources examined were: Commercial Aviation Safety Team (CAST) Safety Enhancements Reserved for Future Implementation (SERFIs), Flight Deck Automation Issues (FDAI) and NTSB Most Wanted List and Open Recommendations. Various automation issues taxonomies and priority lists pertaining to human factors, automation and flight design were combined to create a list of automation issues related to CDM.

Promoting Ethical Research With American Indian and Alaska Native People Living in Urban Areas

PubMed Central

Bartgis, Jami; Demers, Deirdre

2014-01-01

Most health research with American Indian and Alaska Native (AI/AN) people has focused on tribal communities on reservation lands. Few studies have been conducted with AI/AN people living in urban settings despite their documented health disparities compared with other urban populations. There are unique considerations for working with this population. Engaging key stakeholders, including urban Indian health organization leaders, tribal leaders, research scientists and administrators, and policymakers, is critical to promoting ethical research and enhancing capacity of urban AI/AN communities. Recommendations for their involvement may facilitate an open dialogue and promote the development of implementation strategies. Future collaborations are also necessary for establishing research policies aimed at improving the health of the urban AI/AN population. PMID:25211730

A review of adolescent high-intensity interval training.

PubMed

Logan, Greig R M; Harris, Nigel; Duncan, Scott; Schofield, Grant

2014-08-01

Despite the promising evidence supporting positive effects of high-intensity interval training (HIIT) on the metabolic profile in adults, there is limited research targeting adolescents. Given the rising burden of chronic disease, it is essential to implement strategies to improve the cardiometabolic health in adolescence, as this is a key stage in the development of healthy lifestyle behaviours. This narrative review summarises evidence of the relative efficacy of HIIT regarding the metabolic health of adolescents. Methodological inconsistencies confound our ability to draw conclusions; however, there is meaningful evidence supporting HIIT as a potentially efficacious exercise modality for use in the adolescent cohort. Future research must examine the effects of various HIIT protocols to determine the optimum strategy to deliver cardiometabolic health benefits. Researchers should explicitly show between-group differences for HIIT intervention and steady-state exercise or control groups, as the magnitude of difference between HIIT and other exercise modalities is of key interest to public health. There is scope for research to examine the palatability of HIIT as an exercise modality for adolescents through investigating perceived enjoyment during and after HIIT, and consequent long-term exercise adherence.

The Future of Endothelin Research: Scientific Mentoring and Beyond

PubMed Central

Barton, Matthias; Pollock, David M.

2013-01-01

Endothelium-dependent regulation of vascular tone was one of the key discoveries in physiology in the 1980s, including the characterization of endothelium-derived vasoactive factors such as endothelin. Young investigators, often while starting research as part of their PhD degree, have been instrumental in carrying out the work that led some of the most important discoveries in the endothelin field. This article reviews the importance of mentoring for research in general and for endothelin research in particular, including examples of outstanding young investigators that have been instrumental in some of the key discoveries in the endothelin field. Recognizing scientific excellence among young investigators has a long tradition in the history of the International Conferences on Endothelin. Winners of “Young Investigator Awards” of the past five endothelin conferences (ET-8, ET-9, ET-10, ET-11, and ET-12) are presented, as well as recipients of the “ET-12 Best Presentation Awards” established on the occasion of the Twelfth International Conference on Endothelin ET-12 in Cambridge in September 2011. PMID:22796368

The evolution and future of diversity at work.

PubMed

Roberson, Quinetta; Ryan, Ann Marie; Ragins, Belle Rose

2017-03-01

This article examines the evolution of diversity in the Journal of Applied Psychology. To begin, we explore foundations of the concept of diversity, including its appearance in both applied contexts and the scholarly literature. We then review the literature on diversity, including the development of its conceptualization and operationalizations over time, in the Journal and in the field of applied psychological science at large. We also examine the processes underlying the effects of diversity, and specific outcomes of diversity in organizations. To conclude, we offer a future research agenda that highlights diversity-related topics and issues important for advancing an understanding of diversity and moving the field forward, especially within the Journal. This work makes several contributions to research on diversity in organizations. First, we provide a lens for examining change in the study of diversity over time as well as a critical examination of the benefits and challenges associated with these changes. Second, we review the underlying mechanisms and key contextual influences on diversity effects in organizations. Third, our review examines the explanatory power of current diversity research and then uses this to develop a research agenda. By organizing the broad body of literature that exists on diversity, our article offers a sharp picture of what gaps in knowledge exist and where future research should focus. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Changes in glaciers in the Swiss Alps and impact on basin hydrology: current state of the art and future research.

PubMed

Pellicciotti, F; Carenzo, M; Bordoy, R; Stoffel, M

2014-09-15

Switzerland is one of the countries with some of the longest and best glaciological data sets. Its glaciers and their changes in response to climate have been extensively investigated, and the number and quality of related studies are notable. However, a comprehensive review of glacier changes and their impact on the hydrology of glacierised catchments for Switzerland is missing and we use the opportunity provided by the EU-FP7 ACQWA project to review the current state of knowledge about past changes and future projections. We examine the type of models that have been applied to infer glacier evolution and identify knowledge gaps that should be addressed in future research in addition to those indicated in previous publications. Common characteristics in long-term series of projected future glacier runoff are an initial peak followed by a decline, associated with shifts in seasonality, earlier melt onset and reduced summer runoff. However, the quantitative predictions are difficult to compare, as studies differ in terms of model structure, calibration strategies, input data, temporal and spatial resolution as well as future scenarios used for impact studies. We identify two sources of uncertainties among those emerging from recent research, and use simulations over four glaciers to: i) quantify the importance of the correct extrapolation of air temperature, and ii) point at the key role played by debris cover in modulating glacier response. Copyright © 2014 Elsevier B.V. All rights reserved.

The Future of Cardiac Imaging: Report of a Think Tank Convened by the American College of Cardiology.

PubMed

Douglas, Pamela S; Cerqueira, Manuel D; Berman, Daniel S; Chinnaiyan, Kavitha; Cohen, Meryl S; Lundbye, Justin B; Patel, Rajan A G; Sengupta, Partho P; Soman, Prem; Weissman, Neil J; Wong, Timothy C

2016-10-01

The American College of Cardiology's Executive Committee and Cardiovascular Imaging Section Leadership Council convened a discussion regarding the future of cardiac imaging among thought leaders in the field during a 2 day Think Tank. Participants were charged with thinking broadly about the future of imaging and developing a roadmap to address critical challenges. Key areas of discussion included: 1) how can cardiac imaging services thrive in our new world of value-based health care? 2) Who is the cardiac imager of the future and what is the role of the multimodality imager? 3) How can we nurture innovation and research in imaging? And 4) how can we maximize imaging information and optimize outcomes? This document describes the proceedings of this Think Tank. Copyright © 2016 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

Conclusions, synthesis, and future directions: understanding sources of population change

USGS Publications Warehouse

Esler, Daniel N.; Flint, Paul L.; Derksen, Dirk V.; Savard, Jean-Pierre L.; Eadie, John M.

2015-01-01

The material in this volume reflects the burgeoning interest in sea ducks, both as study species with compelling and unique ecological attributes and as taxa of conservation concern. In this review, we provide perspective on the current state of sea duck knowledge by highlighting key findings in the preceding chapters that are of particular value for understanding or influencing population change. We also introduce a conceptual model that characterizes links among topics covered by individual chapters and places them in the context of demographic responses. Finally, we offer recommendations for areas of future research that we suggest will have importance for understanding and managing sea duck population dynamics.

Cost Analysis of Renewable Energy-Based Microgrids

DOE Office of Scientific and Technical Information (OSTI.GOV)

Giraldez Miner, Julieta I; Singh, Shruti; Gao, David Wenzhong

This paper analyzes the cost composition of microgrid construction as well as the influencing key factors. The Microgrid Cost Study aims at identifying the average cost of a typical microgrid project. The project is limited to the vicinity of U.S. and hence takes into account of only existing microgrid projects in U.S. The project's objective is to find cost of microgrid and its individual components for next 5 years. This will help in R&D for future microgrid projects as well as help investors/developers/researchers get an idea about the cost of their projects that they might want to start in nearmore » future.« less

Surface chemistry: Key to control and advance myriad technologies

PubMed Central

Yates, John T.; Campbell, Charles T.

2011-01-01

This special issue on surface chemistry is introduced with a brief history of the field, a summary of the importance of surface chemistry in technological applications, a brief overview of some of the most important recent developments in this field, and a look forward to some of its most exciting future directions. This collection of invited articles is intended to provide a snapshot of current developments in the field, exemplify the state of the art in fundamental research in surface chemistry, and highlight some possibilities in the future. Here, we show how those articles fit together in the bigger picture of this field. PMID:21245359

The Evolution of Exercise Hardware on ISS: Past, Present, and Future

NASA Technical Reports Server (NTRS)

Buxton, R. E.; Kalogera, K. L.; Hanson, A. M.

2017-01-01

During 16 years in low-Earth orbit, the suite of exercise hardware aboard the International Space Station (ISS) has matured significantly. Today, the countermeasure system supports an array of physical-training protocols and serves as an extensive research platform. Future hardware designs are required to have smaller operational envelopes and must also mitigate known physiologic issues observed in long-duration spaceflight. Taking lessons learned from the long history of space exercise will be important to successful development and implementation of future, compact exercise hardware. The evolution of exercise hardware as deployed on the ISS has implications for future exercise hardware and operations. Key lessons learned from the early days of ISS have helped to: 1. Enhance hardware performance (increased speed and loads). 2. Mature software interfaces. 3. Compare inflight exercise workloads to pre-, in-, and post-flight musculoskeletal and aerobic conditions. 4. Improve exercise comfort. 5. Develop complimentary hardware for research and operations. Current ISS exercise hardware includes both custom and commercial-off-the-shelf (COTS) hardware. Benefits and challenges to this approach have prepared engineering teams to take a hybrid approach when designing and implementing future exercise hardware. Significant effort has gone into consideration of hardware instrumentation and wearable devices that provide important data to monitor crew health and performance.